previous compound ID: 3 next compound
InChIKey: FJNFVCAHHFNREI-UHFFFAOYSA-N
SMILES: CC(C1=NC2=CC=CC=C2C(=N1)OC3CCCCC3)N4CCN(CC4)S(=O)(=O)C5=CC=C(C=C5)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

ReferenceID: 15
"DM Clarke" "MC Bartlett" "Y Wang" "TW Loo"
ReferenceID: 73
"N Pedemonte" "V Tomati" "LJ Galietta" "E Caci" "E Sondo" "U Pfeffer" "AI Esposito"
ReferenceID: 72
"JP Clancy" "PA Sloane" "B Woodworth" "LC Pyle" "Y Li" "J Fortenberry" "J Fulton" "L Fan" "SM Rowe" "J Collawn" "A Jurkevante" "M Mazur" "EJ Sorscher" "K Varga"
ReferenceID: 57
"P Kim Chiaw" "L Wellhauser" "M Ramjeesingh" "LJ Huan" "CE Bear"
ReferenceID: 42
"P Lesimple" "BJ Scholte" "J Liao" "DY Thomas" "HR de Jonge" "D Rotin" "M Wilke" "N Liu" "H Balghi" "R Robert" "JW Hanrahan" "B Kus" "GW Carlile"
ReferenceID: 53
"D Rotin" "SD Macknight" "R Robert" "JW Hanrahan" "B Kus" "J Liao" "J Goepp" "E Matthes" "GW Carlile" "DY Thomas"
ReferenceID: 82
"D Waller" "R Phillipe" "P Lesimple" "F Dantzer" "J Liao" "DY Thomas" "F Ciciriello" "HM Sampson" "DL Zhang" "H Balghi" "R Robert" "JW Hanrahan" "SM Anjos" "P Ferraro" "J Goepp" "GW Carlile"
ReferenceID: 80
"J Rader" "D Cao" "T Neuberger" "KS Straley" "A Hazlewood" "V Panchenko" "T Knapp" "M Miller" "P Negulescu" "S Hadida" "E Olson" "JH Stack" "LR Makings" "J González" "J Joubran" "A Singh" "R Tung" "F Van Goor" "PD Grootenhuis"
ReferenceID: 84
"L Yan" "RA Keyzers" "CA Gray" "J Liao" "DE Williams" "D Zhang" "DY Thomas" "HM Sampson" "R Robert" "JW Hanrahan" "SM Anjos" "RG Linington" "RM Centko" "GW Carlile" "RJ Andersen" "KA Teske"


CID is 11957831
synonyms found at PubChem are:
815592-21-3, 4-(cyclohexyloxy)-2-(1-(4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl)ethyl)quinazoline, CFcor-325, VRT-325, 4-(Cyclohexyloxy)-2-(1-(4-(4-methoxyphenylsulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl}ethyl)quinazoline, ACMC-20p1e2, GTPL4340, SCHEMBL3822809, VRT325, CHEMBL1257047, CTK9A5799, DTXSID00474707, VRT 325, MolPort-006-415-015, KS-000000GF, AKOS030228615, 4-cyclohexyloxy-2-[1-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethyl]quinazoline, KB-01359, KB-34900, A1-01884, 4-(Cyclohexyloxy)-2-(1-(4-((4-methoxyphenyl)sulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl}ethyl)quinazoline