CandActCFTR Seed Compounds


The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.



ID: 1501

chemical graph of compound 1501



InChIKey: NOFOAYPPHIUXJR-APNQCZIXSA-N
SMILES: C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 457964
synonyms found at PubChem are:
aphidicolin, 38966-21-1, ICI 69653, NSC 234714, NSC-234714, UNII-192TJ6PP19, CCRIS 1783, NSC234714, BRN 4689958, CHEMBL29711, MLS000069677, CHEBI:2766, 192TJ6PP19, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol, 9,15-Cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3alpha,4alpha,5alpha,17alpha)-, SMR000058538, (+)-Aphidicolin, NSC-351140, 8,11a-Methano-11aH-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R-(3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta,11a-beta,11b-beta))-, (+/-)-Aphidicolin, Aphidicolin, (+/-)-, aphidicholin, aphidocolin, bis(hydroxymethyl)-dimethyl-[?]diol, ICI-69653, AC1L9XIU, Opera_ID_1321, CBiol_001873, BSPBio_001438, KBioGR_000158, KBioSS_000158, SCHEMBL183956, cid_457964, MEGxm0_000277, Aphidicolin, analytical standard, DTXSID5036711, ACon0_000080, ACon1_000511, BCBcMAP01_000163, KBio2_000158, KBio2_002726, KBio2_005294, KBio3_000315, KBio3_000316, BIA4316, MolPort-001-739-525, ZX-AFC000241, Bio1_000159, Bio1_000648, Bio1_001137, Bio2_000158, Bio2_000638, HMS1361H20, HMS1791H20, HMS1989H20, HMS3402H20, ZINC3789195, Aphidicolin from Nigrospora sphaerica, BDBM50090910, MFCD00083214, AKOS027470273, CCG-208640, MCULE-1655552736, IDI1_033908, SMP1_000025, NCGC00023142-03, NCGC00023142-04, NCGC00023142-05, NCGC00023142-06, 69926-98-3, 8,11a-Methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-rel-, LS-90736, 3alpha,16,17,18-tetrahydroxyaphidicolone, 966A211, C-55158, UNII-6B3F8QW8TU component NOFOAYPPHIUXJR-APNQCZIXSA-N, 4B15B386-8738-48FE-80DB-5BA3406098DD, Aphidicolin from Nigrospora sphaerica, >=98% (HPLC), powder, (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-Bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.0[1,10].0[2,7]]hexadecane-5,13-diol, (3alpha,4alpha,5alpha,17alpha)-3,17-dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, 2ZE, 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol, 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R,10S,12R,13R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol (Aphidicolin), 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R,10S,12R,13R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol(Aphidicolin), 8,11a-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3S,4R,4aR,6aS,8R,9R,11aS,11bS)-


ID: 1502

chemical graph of compound 1502



InChIKey: NOIIUHRQUVNIDD-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CNC(=O)CCNNC(=O)C2=CC=NC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4472
synonyms found at PubChem are:
Nialamide, Nialamid, Niamidal, Niaquitil, Niamid, Niazin, Psicodisten, Novazid, Nuredal, Nyazin, Surgex, Mygal, 51-12-7, Delmoneurina, Isalizina, Espril, BEIH, Delmoneurinaesprilisalizina, Nialamida, Nialamidum, Nialamidum [INN-Latin], Nialamida [INN-Spanish], Nyezin, UNII-T2Q0RYM725, N-(2-(Benzylcarbamyl)ethylamino)isonicotinamide, P 1133, NSC 124514, CCRIS 3512, 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid, 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid, N-Isonicotinyl hydrazide, EINECS 200-079-3, Lopac-N-1392, N-Benzyl-3-(2-isonicotinoylhydrazino)propanamide, N-Benzyl-beta-(isonicotinoylhydrazine)propionamide, BRN 0492941, 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine, MLS000069474, Isonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazide, N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine, T2Q0RYM725, NOIIUHRQUVNIDD-UHFFFAOYSA-N, 4-Pyridinecarboxylic acid, 2-[3-oxo-3-[(phenylmethyl)amino]propyl]hydrazide, NSC124514, 1-[2-(Benzylcarbamoyl)ethyl]-2-isonicotinoylhydrazine, Isonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazide, CAS-51-12-7, Isonicotinic acid, 2-[2-(benzylcarbamoyl)ethyl]hydrazide, NCGC00015726-06, SMR000059131, N(sup1)-beta-Benzylcarbamoylethyl-N(sup2)-isonicotinoylhydrazine, N(sup 1)-beta-Benzylcarbamoylethyl-N(sup 2)-isonicotinoylhydrazine, DSSTox_CID_3362, 4-Pyridinecarboxylic acid 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide, 4-Pyridinecarboxylic acid, 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide, DSSTox_RID_76991, DSSTox_GSID_23362, N-Benzyl-.beta.-(isonicotinylhydrazino)propionamide, N-Benzyl-.beta.-(isonicotinoylhydrazine)propionamide, 2-[2-(Benzylcarbamoyl)ethyl]hydrazide isonicotinic acid, Isonicitinic acid 2-[(2-benzylcarbamoyl)ethyl]hydrazide, Isonicotinic acid, 2-[2-(benzylcarbamoylethyl]hydrazide, N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazinyl]propanamide, N-Isonicotinoyl-N'-(.beta.-N-benzylcarboxamidoethyl)hydrazine, 4-Pyridinecarboxylic acid 2-[3-oxo-3-[(phenylmethyl)amino]propyl]hydrazide, Nialamide [INN:BAN], SR-01000000028, Nialamide [INN:BAN:NF], HSDB 7698, Nialamide (INN), Nialamide, 95%, Niamid (TN), nialamide (substance), NF-XIII, Opera_ID_1336, Prestwick0_001099, Prestwick1_001099, Prestwick2_001099, Prestwick3_001099, CBChromo1_000220, AC1L1I8S, AC1Q5HC8, Nucleic Acid Electrophoresis, Lopac0_000865, SCHEMBL49430, BSPBio_001178, 5-22-02-00251 (Beilstein Handbook Reference), MLS001076132, MLS001424258, SPBio_003059, WLN: T6NJ DVMM2VM1R, BPBio1_001296, CHEMBL1256841, DTXSID1023362, CHEBI:94510, CTK8G1845, MolPort-001-783-584, BDBM163693, HMS1571K20, HMS2052O21, HMS2089M13, HMS2093L10, HMS2098K20, HMS2233A06, HMS3262N11, HMS3372J15, HMS3394O21, HMS3715K20, Pharmakon1600-01505986, ACM51127, HY-B1199, ZINC1713761, Tox21_110208, Tox21_500865, 2586AH, NSC759298, AKOS003390166, Tox21_110208_1, CCG-101150, CS-4827, DB04820, LP00865, MCULE-7326088210, NC00400, NSC-124514, NSC-759298, NCGC00015726-01, NCGC00015726-02, NCGC00015726-03, NCGC00015726-04, NCGC00015726-05, NCGC00015726-07, NCGC00015726-08, NCGC00015726-09, NCGC00015726-11, NCGC00022832-03, NCGC00022832-04, NCGC00261550-01, CPD000059131, LS-84849, SAM001246861, SBI-0050840.P002, AB00384282, EU-0100865, FT-0631220, ST45022574, D07337, N 1392, AB00384282-14, AB00384282_15, AB00384282_16, C-18665, N-benzyl-3-(2-isonicotinoylhydrazinyl)propanamide, N-Benzyl- beta-[isonicotinyl-hydrazine] propionamide, N-Benzyl-3-(2-isonicotinoylhydrazino)propanamide #, N-Benzyl-beta-[isonicotinyl-hydrazine] propionamide, SR-01000000028-2, SR-01000000028-5, SR-01000000028-7, SR-01000000028-8, BRD-K12102668-001-04-0, N-benzyl-3-[(4-pyridylcarbonylamino)amino]propanamide, 2-(2-(Benzylcarbamoyl)ethyl)hydrazide, isonicotinic acid, N1-.beta.-Benzylcarbamoylethyl-N2-isonicotinoylhydrazine, Isonicotinic acid, {2-[2-(benzylcarbamoyl)ethyl]hydrazide}, Isonicotinic acid, {2-[2-(benzylcarbamoylethyl]hydrazide}, Isonicotinic acid, 2-[2- (benzylcarbamoyl)ethyl]hydrazide, N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide, Pyridine-4-carboxylic 2-[2-(benzylcarbamoyl)ethyl]hydrazide, 3-[[oxo(pyridin-4-yl)methyl]hydrazo]-N-(phenylmethyl)propanamide, Hydrazine, N-isonicotinoyl-N'-[beta-(N-benzylcarboxamido)ethyl]-, n(sup1)-.beta.-Benzylcarbamoylethyl-n(sup2)isonicotinoylhydrazine, N-(phenylmethyl)-3-[2-(pyridin-4-ylcarbonyl)hydrazino]propanamide, N-Benzyl-3-[N'-(1-pyridin-4-yl-methanoyl)-hydrazino]-propionamide, N-isonicotinoyl-N [ beta-(N-benzyl-carboxamido) ethyl] hydrazine, N-isonicotinoyl-N' [ beta-(N-benzyl-carboxamido) ethyl] hydrazine, 4-Pyridinecarboxylic acid, 2-(3-oxo-3-((phenylmethyl)amino)propyl)hydrazide (9CI)


ID: 1503

chemical graph of compound 1503



InChIKey: NOJMTMIRQRDZMT-GSPXQYRGSA-N
SMILES: CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 31100
synonyms found at PubChem are:
BROMOCRIPTINE MESYLATE, Bromocriptine mesilate, Bromocryptine mesylate, Pravidel, Bagren, 22260-51-1, Bromergon, CB-154 mesylate, UNII-FFP983J3OD, 2-Bromo-alpha-ergocryptine mesylate, Bromocriptine methanesulfonate, Bromocryptine methanesulfonate, CB 154, Bromocriptine (mesylate), EINECS 244-881-1, FFP983J3OD, 2-Bromo-alpha-ergocryptine methanesulfonate, CHEBI:3182, 2-Bromine-alpha-ergocryptine methanesulfonate, 2-Bromo-alpha-ergokryptine-mesilate [German], CB-154, 2-Bromoergocryptine monomethanesulfonate (salt), Parlodel (TN), 2-Bromoergocryptine, alpha-Ergocryptine, 2-bromo-, methanesulfonate, 2-Bromo-12'-hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate, (+)-Bromocriptine methanesulfonate, Cycloset, oline-9-carboxamide methanesulfonate, Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, monomethanesulfonate (salt), (5'alpha)-, NSC169774, 2-Bromoergocryptine Mesylate, SR-01000597796, Bromocriptine mesylate [USAN], SR-01000075356, C32H40BrN5O5.CH4O3S, Bromocriptine mesylate [USAN:USP], (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman methanesulfonate (salt), (6aR,9R)-5-Bromo-N-[(2R,5S,10aS,10bS)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quin, 2-Bromo-alpha-ergokryptine-mesilate, Prestwick_771, CAS-22260-51-1, AC1L1KXP, DSSTox_CID_197, DSSTox_RID_75426, DSSTox_GSID_20197, SCHEMBL40559, Bromocriptine mesylate (USP), Bromocriptine mesilate (JP17), CHEMBL1200503, DTXSID6020197, CB 154 methanesulfonate (salt), 2-Bromo |A-Ergocryptine Mesylate, MolPort-006-123-738, NOJMTMIRQRDZMT-GSPXQYRGSA-N, HMS1568I04, HMS3260D03, HMS3712I04, 25614-03-3 (Parent), 2-Bromo alpha-Ergocryptine Mesylate, Tox21_303597, Tox21_500171, HY-12705A, .alpha.-Ergocryptine, methanesulfonate, AKOS015896276, CCG-220121, CCG-221475, CS-6048, LP00171, LS-7234, NSC-169774, NCGC00257268-01, NCGC00260856-01, AN-17214, 2-Bromo-a-ergocryptine methanesulfonate salt, B6298, EU-0100171, B 2134, D00780, 2-Bromo-.alpha.-ergocryptine monomethanesulfonate, 93201-EP2272825A2, 93201-EP2305633A1, I06-2158, SR-01000075356-1, SR-01000597796-1, SR-01000597796-2, (5 inverted exclamation mark |A)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione Methanesulfonate, (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate, (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman methanesulfonate, (5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman methanesulfonate, (5xi,5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxoergotaman methanesulfonate (salt), (5xi,5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman methanesulfonate (salt)


ID: 1504

chemical graph of compound 1504



InChIKey: NOXMJZCFMAEDRF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C#CCN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957674
synonyms found at PubChem are:
30011-36-0, 3-Phenyl-2-propyn-1-amine hydrochloride, 3-phenylprop-2-yn-1-amine hydrochloride, 3-Phenylpropargylamine hydrochloride, 2-Propyn-1-amine, 3-phenyl-, hydrochloride, ACMC-20amyy, EU-0101016, 3-Phenylpropargylamine HCl, AC1Q3D3E, SCHEMBL1321859, CHEMBL1255940, CTK8C5930, DTXSID80474700, MolPort-003-959-146, GEO-02128, AKOS025146872, NE11082, NCGC00094308-01, AN-25056, DB-068195, TC-169441, FT-0733875, P-106, EN300-26681, 3-Phenyl-2-propyn-1-amine hydrochloride, 97%, SR-01000075637, SR-01000075637-1, W-200290


ID: 1505

chemical graph of compound 1505



InChIKey: NPBNRBWMDNZEBN-YTEKVJICSA-N
SMILES: CC([C@H]1CCC2[C@@]1(CCC3C2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6728949
synonyms found at PubChem are:
3beta-hydroxy-23,24-bisnorchol-5-enic acid, AC1O9AUF, Spectrum2_001949, SPECTRUM270043, SPBio_002017, CCG-39467, SR-05000002607, SR-05000002607-1, 2-[(3S,10R,13S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoic acid


ID: 1506

chemical graph of compound 1506



InChIKey: NPJIOCBFOAHEDO-AVWFULIKSA-N
SMILES: C[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1C)CC2=CC=CC=C2)C(C)C)CCCCN)CC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5311430
synonyms found at PubChem are:
seglitide, 81377-02-8, UNII-5P57R7IR6J, MK 678, MK-678, 5P57R7IR6J, CHEMBL311695, L-363586, Seglitidum, Seglitida, AC1NSKMC, Seglitide < Rec INN >, D09JXL, Lopac0_001105, SCHEMBL151244, GTPL2051, 99248-33-6 (monoacetate), NPJIOCBFOAHEDO-AVWFULIKSA-N, MK678, BDBM50051568, ZINC85537084, AKOS024456805, CCG-205181, Cyclo(D-Trp-Lys-Val-Phe-N-Me-Ala-Tyr), Cyclic (N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe), EU-0101105, Cyclic(N-methyl-Ala-Tyr-D-Trp-Lys-Val-Phe), S 1316, C-23539, SR-01000076118, SR-01000076118-2, (3S,6S,9S,12R,15S,18S)-12-((1H-indol-3-yl)methyl)-9-(4-aminobutyl)-3-benzyl-15-(4-hydroxybenzyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8,11,14,17-hexaone, (3S,6S,9S,12R,15S,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hydroxy-benzyl)-12-(1H-indol-3-ylmethyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16hexaaza-cyclooctadecane-2,5,8,11,14,17-hexaone, (3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-1,18-dimethyl-3-(phenylmethyl)-6-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadecane-2,5,8,11,14,17-hexone, (3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3-benzyl-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-1,18-dimethyl-6-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadecane-2,5,8,11,14,17-hexone


ID: 1507

chemical graph of compound 1507



InChIKey: NPJWANZASAIMBS-HNNXBMFYSA-N
SMILES: C[C@]12CCC(=O)C=C1CCC3=C2C=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708578
synonyms found at PubChem are:
12-HYDROXY-4,4-BISNOR-4,8,11,13-PODOCARPATETRAEN-3-ONE, SPBio_000495, Spectrum_000703, SpecPlus_000162, Spectrum2_000368, Spectrum3_000128, Spectrum4_001406, Spectrum5_000172, AC1O8FE5, BSPBio_001776, KBioGR_001792, KBioSS_001183, SPECTRUM100620, DivK1c_006258, CHEMBL1358735, KBio1_001202, KBio2_001183, KBio2_003751, KBio2_006319, KBio3_000936, CCG-39855, NCGC00095820-01, NCGC00095820-02, (4aS)-6-hydroxy-4a-methyl-3,4,9,10-tetrahydrophenanthren-2-one


ID: 1508

chemical graph of compound 1508



InChIKey: NPLHSMBWWIIWAQ-UHFFFAOYSA-N
SMILES: CN(C)CCCCSC(=N)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957708
synonyms found at PubChem are:
SKF 91488 dihydrochloride, NPLHSMBWWIIWAQ-UHFFFAOYSA-N, 68643-23-2, 68941-21-9, 4-(N,N-Dimethylamino)butylisothiourea dihydrochloride, 4-[N,N-Dimethylamino]butylisothiourea dihydrochloride, SR-01000075291, EU-0101172, SCHEMBL7367775, CHEMBL1398213, MolPort-003-983-684, BN0490, AKOS024458505, NCGC00094429-01, SK & F 91488, SR-01000075291-1, SR-01000075291-3, S-[4-(dimethylamino)butyl]-isothiourea dihydrochloride, S-[4-(dimethylamino)butyl]isothiourea dihydrochloride, [4-(carbamimidoylsulfanyl)butyl]dimethylamine dihydrochloride


ID: 1509

chemical graph of compound 1509



InChIKey: NPRJSFWNFTXXQC-QFWQFVLDSA-N
SMILES: CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5702613
synonyms found at PubChem are:
C6 ceramide, C6-ceramide, N-hexanoylsphingosine, C(6)-ceramide, C6-Cer, C6-l-Erythro-ceramide, UNII-038753E78J, N-(hexanoyl)sphing-4-enine, D-erythro-N-hexanoylsphingosine, CHEBI:63867, Cer(d18:1/6:0), NPRJSFWNFTXXQC-QFWQFVLDSA-N, 124753-97-5, D-erythro-Sphingosine, N-Hexanoyl-, N-hexanoyl-D-erythro-sphingosine, 038753E78J, Caproyl ceramide, Ceramid 6, N-caproylsphingosine, N-Hexanoyl-D-sphingosine, SR-05000002364, N-(2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl)hexanamide, N-((E,2s,3r)-1,3-Dihydroxyoctadec-4-En-2-Yl)hexanamide, N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide, N-Hexanoyl-D-eythro-spingosine, C-6 Ceramide, N-Hexanoylspingosine, NSC 655091, N-Hexanoy-D-sphingosine, AC1NWBN0, (2S,3R,4E)-Ceramide, CHEMBL224877, SCHEMBL13587660, 6-hexanoyl-d-erythro-sphingosine, C24H47NO3, MolPort-003-845-709, HMS3649E07, C6 Ceramide (d18:1/6:0), 1649AH, HSCI1_000109, ZINC16051948, CCG-208164, SMP2_000293, NCGC00163521-01, N-Hexanoyl-D-sphingosine, >=98% (TLC), synthetic, SR-05000002364-2, SR-05000002364-3, 6-Hexanoyl-D-erythro-sphingosine, 99+%, synthetical, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexanamide, 6CM


ID: 1510

chemical graph of compound 1510



InChIKey: NPYOKEDYJXYSTA-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C3C(=CC(=C2O1)OC)C(=O)C(=CO3)C4=CC5=C(C=C4OC)OCO5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3428129
synonyms found at PubChem are:
Ichthynone, 24340-62-3, KBio1_001675, Spectrum_000753, SpecPlus_000635, Spectrum2_000758, Spectrum3_000142, Spectrum4_001421, Spectrum5_000242, AC1MP1K4, BSPBio_001844, KBioGR_001862, KBioSS_001233, DivK1c_006731, SPBio_000776, SCHEMBL9924621, CHEMBL3039125, ACon1_001745, CHEBI:92492, KBio2_001233, KBio2_003801, KBio2_006369, KBio3_001044, DTXSID50392386, CCG-39041, LMPK12050122, SDCCGMLS-0066457.P001, NCGC00178961-01, NCGC00178961-02, BRD-K28167849-001-02-1, 6-methoxy-3-(6-methoxy-1,3-benzodioxol-5-yl)-8,8-dimethylpyrano[2,3-h]chromen-4-one


ID: 1511

chemical graph of compound 1511



InChIKey: NQWRSILGEXNJIT-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957553
synonyms found at PubChem are:
GBR 12935 dihydrochloride, 67469-81-2, GBR-12935 dihydrochloride, GBR 12935 (dihydrochloride), 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride, 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE, GBR 12935 HCl, CHEBI:64091, MFCD00083175, NQWRSILGEXNJIT-UHFFFAOYSA-N, 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride, 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-piperazine dihydrochloride, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazinediium dichloride, SR-01000075429, 1-(2-(Benzhydryloxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride, 76778-22-8, EU-0100560, GBR12935 dihydrochloride, GBR12935(dihydrochloride), C28H34N2O.2ClH, SCHEMBL339982, GBR-12935 2HCl, CHEMBL1330764, DTXSID6042573, CTK8G0008, KS-00001CWV, AOB2532, EX-A451, MolPort-003-983-577, BCP09762, Tox21_500560, 3692AH, BN0221, AKOS024458512, AN-3496, CCG-221864, CS-3130, LP00560, NCGC00093945-01, NCGC00261245-01, 4CA-0553, HY-12242, 67469-81-2 (HCl), KB-310867, LS-111942, FT-0726457, G 9659, C-55147, SR-01000075429-1, SR-01000075429-3, GBR 12935 dihydrochloride, >=98% (TLC), powder, 1-(2-benzhydryloxyethyl)-4-(3-phenylpropyl)piperazine dihydrochloride, 1-(2-benzhydryloxyethyl)-4-(3-phenylpropyl)piperazine;dihydrochloride, 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE 2HCL, Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2)


ID: 1512

chemical graph of compound 1512



InChIKey: NRDWUPPIGBHWAS-ZJUUUORDSA-N
SMILES: CCC[C@H]1CC2=C(C[C@H](CC3=C1C(=O)OC3=O)CC)C(=O)OC2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 164723
synonyms found at PubChem are:
Byssochlamic acid, 743-51-1, (+)-Byssoclamic acid, Spectrum_000288, SpecPlus_000589, Spectrum2_001829, Spectrum3_001705, Spectrum4_001852, Spectrum5_000384, AC1L4VC7, BSPBio_003290, KBioGR_002285, KBioSS_000768, DivK1c_006685, SPBio_001877, CHEMBL3039421, CHEBI:92764, CTK5D9759, KBio1_001629, KBio2_000768, KBio2_003336, KBio2_005904, KBio3_002510, DTXSID80225315, CCG-38459, SDCCGMLS-0066921.P001, NCGC00178159-01, BRD-K43468059-001-02-9, 1H-Cyclonona(1,2-c:5,6-c')difuran-1,3,6,8(4H)-tetrone, 10-ethyl-5,9,10,11-tetrahydro-4-propyl-, (4S-(4R*,10S*))-, 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6,8(4H)-tetrone,10-ethyl-5,9,10,11-tetrahydro-4-propyl-, (4S,10R)-


ID: 1513

chemical graph of compound 1513



InChIKey: NRHUDETYKUBQJT-BTQNPOSSSA-N
SMILES: CCCN1CCC[C@H](C1)C2=CC(=CC=C2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957669
synonyms found at PubChem are:
PRECLAMOL HYDROCHLORIDE, UNII-Q8W2T87WWW, S(-)-3PPP hydrochloride, 88768-67-6, Q8W2T87WWW, R-3-PPP hydrochloride, (S)-(-)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, S-(-)-3-PPP, S(-)-3-PPP HCl, NCGC00094285-01, DSSTox_CID_25796, DSSTox_RID_81136, DSSTox_GSID_45796, MLS002153168, SCHEMBL3692396, CHEMBL1255842, DTXSID1045796, Tox21_111264, Tox21_500996, MFCD00069366, AKOS024418759, CCG-222300, LP00996, NCGC00261681-01, SMR000326863, CAS-85976-54-1, EU-0100996, P-103, 85976-54-1, Phenol, 3-(1-propyl-3-piperidinyl)-, hydrochloride, (S)-, (S)-()-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, (S)-(-)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, >=98% (HPLC), solid


ID: 1514

chemical graph of compound 1514



InChIKey: NRHUDETYKUBQJT-ZOWNYOTGSA-N
SMILES: CCCN1CCC[C@@H](C1)C2=CC(=CC=C2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 202477
synonyms found at PubChem are:
R(+)-3PPP hydrochloride, UNII-S695806J1A, R(+)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, R(+)-3-PPP hydrochloride, 89874-80-6, S695806J1A, R-3-PPP hydrochloride, SR-01000075393, Preclamol hydrochloride, (R)-, R-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, C14H21NO, NCGC00094285-01, AC1L48LS, MLS002153291, SCHEMBL7202473, CHEMBL1255841, Tox21_500986, MFCD00055194, CCG-222290, LP00986, NCGC00261671-01, SMR000326829, LS-105092, EU-0100986, P-102, (R)-(+)-3-(3-Hydroxy-phenyl)-N-propylpiperidine, SR-01000075393-1, SR-01000075393-2, 3-[(3R)-1-propylpiperidin-3-yl]phenol hydrochloride, n-N-propyl-3-(3-hydroxyphenyl)piperidine, R-(+)-isomer, R(+)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride, solid


ID: 1515

chemical graph of compound 1515



InChIKey: NSFHBVDUKHPTKG-ATVHPVEESA-N
SMILES: CC(C)C/C(=N\NC1=NC(=CS1)C2=CC=CC=C2)/C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"O Zegarra-Moran" "GL Lukacs" "AS Verkman" "E Caci" "N Pedemonte" "K Du" "LJ Galietta"


CID is 5776947
synonyms found at PubChem are:
AC1NXCUP, SCHEMBL838235, AKOS001588113, AKOS024374137, ST51013503, 2-((2Z)-3,5-dimethyl-1,2-diazahex-2-enylidene)-4-phenyl-1,3-thiazoline, N-[(Z)-4-methylpentan-2-ylideneamino]-4-phenyl-1,3-thiazol-2-amine


ID: 1516

chemical graph of compound 1516



InChIKey: NSRJSISNDPOJOP-BBRMVZONSA-N
SMILES: COC1=CC2=C(C=C1)[C@@H]3COC4=C([C@@H]3O2)C=CC(=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 336327
synonyms found at PubChem are:
Medicarpin, (-)-Medicarpin, Demethylhomopterocarpin, 32383-76-9, Medicarpin, (-)-, (l)-De-o-methylhomopterocarpan, l-3-Hydroxy-9-methoxypterocarpan, UNII-6TX086I6IG, (-) Medicarpin, (-)-3-Hydroxy-9-methoxypterocarpan, NSC350085, NSC 350085, (-)-Demethylhomopterocarpin, 3-Hydroxy-9-methoxypterocarpan, CHEBI:100, 6TX086I6IG, (6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol, 6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, cis-, AC1L7JEM, (6aR,11aR)-medicarpin, SCHEMBL72476, MLS000697611, CHEMBL238845, MEGxp0_001319, ACon1_001568, ZINC11544, MolPort-001-741-647, NSRJSISNDPOJOP-BBRMVZONSA-N, HMS2270J20, 6a,11a-Dihydro-9-methoxy-6H-benzofuro(3,2-c)(1)benzopyran-3-ol, LMPK12070028, 3-Hydroxy-9-methoxypterocarpan, (-), AKOS032948389, MCULE-2988094761, NSC-350085, 6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, (6aR-cis)-, NCGC00180373-01, NCI60_003118, SMR000470945, C10503, 6H-Benzofuro[3, 6a,11a-dihydro-9-methoxy-, cis-, BRD-K20359375-001-01-6, 6H-Benzofuro[3, 6a,11a-dihydro-9-methoxy-, (6aR-cis)-, (6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-3-ol, 9-Methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol, cis-, 6H-Benzofuro(3,2-c)(1)benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, cis- (8CI), 6H-Benzofuro[3, 2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, (6aR-cis)-, 6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, cis-(-)-, NCGC00180373-02!(6aR,11aR)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol


ID: 1517

chemical graph of compound 1517



InChIKey: NSYSSMYQPLSPOD-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=O)O1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 54675757
synonyms found at PubChem are:
4-Hydroxy-6-methyl-2-pyrone, 675-10-5, 2-Hydroxy-6-methyl-4H-pyran-4-one, 4-Hydroxy-6-methyl-2H-pyran-2-one, 70254-61-4, Triacetate lactone, Triacetic acid lactone, 4-hydroxy-6-methylpyran-2-one, 2H-PYRAN-2-ONE, 4-HYDROXY-6-METHYL-, 6-Methyl-4-hydroxypyron-(2), UNII-S1S883S4EE, NSC 34625, 6-methyl-4-hydroxy-2-pyrone, CCRIS 3600, 4-Hydroxy-6-methylpyran-4-one, EINECS 211-619-2, BRN 0113815, CHEMBL54907, S1S883S4EE, CHEBI:16458, NSYSSMYQPLSPOD-UHFFFAOYSA-N, PubChem9569, Spectrum_001904, SpecPlus_000816, Spectrum2_001978, Spectrum3_001720, Spectrum4_001907, Spectrum5_000594, 4-hydroxy-6-methylpyrone, 6-methyl-4-hydroxypyrone, ACMC-1BI0S, 4-hydroxy-6-methyl-pyrone, 4-hydroxy-6-methylpyranone, 4-hydroxy-6-methyl pyranone, BSPBio_003340, KBioGR_002500, KBioSS_002438, 4-hydoxy-6-methyl-2-pyrone, KSC356A1J, DivK1c_006912, SCHEMBL320025, SCHEMBL918518, SPECTRUM1600759, SPBio_002135, 4- hydoxy-6-methyl-2-pyrone, 2-hydroxy-6-methylpyran-4-one, 4-hydroxy- 6-methyl-2-pyrone, 4-hydroxy-6 -methyl-2-pyrone, 4-hydroxy-6-methyl pyr-2-one, 4-Hydroxy-6-Methyl-a-pyrone;, 6-Methyl-4-hydroxypyran-2-one, DTXSID1060974, CTK2F6014, CTK8C2277, KBio1_001856, KBio2_002432, KBio2_005000, KBio2_007568, KBio3_002560, KS-00000QID, 2-hydroxy-6-methyl-pyran-4-one, 4-hydroxy-6-methyl-pyran-2-one, 6-methyl-4-hydroxy pyran-2-one, MolPort-000-156-355, MolPort-004-803-931, OOKCZXGEYPSNIM-UHFFFAOYSA-N, 3,5-Dihydroxysorbic acid d-lactone, AC1L2030, ALBB-021321, NSC34625, ZERO/001810, ZINC4273393, 0884AC, ANW-35356, ANW-68127, BBL008420, BDBM50405204, CCG-39516, NSC-34625, SBB001910, STK772128, 4-Hydroxy-6-methyl-2-oxo-2H-pyran, 4-Hydroxy-6-methyl-2-pyrone, 98%, AKOS000119605, AKOS016007260, ZINC100045433, 3,5-Dihydroxysorbic acid delta-lactone, CS-W020045, LS40924, MCULE-4178961944, RP19667, RTR-022673, SDCCGMLS-0066925.P001, TRA0068312, VZ35471, 4-HYDROXY-6-METHYL-2-PYRONONE, 4H-Pyran-4-one, 2-hydroxy-6-methyl-, NCGC00095976-01, NCGC00095976-02, NCGC00178130-01, AC-27196, AJ-50035, AN-47181, BC678859, BR-44057, DA-17115, H349, KB-72555, SC-53888, AB0013001, DB-055039, KB-230914, LS-127456, ST4083834, TC-156872, TL8004760, TR-022673, FT-0618665, FT-0715301, ST24023568, 75H105, 7H-939, C02752, M-6213, 4H-Pyran-4-one, 2-hydroxy-6-methyl- (9CI), 102190-EP2281817A1, 102190-EP2301922A1, SR-05000002374, I14-9760, SR-05000002374-1, W-104713, BRD-K77202630-001-02-9, BRD-K77202630-001-03-7, F0001-1779, Z1250100716, 3,5-Dihydroxysorbic acid |A-lactone;4-Hydroxy-6-Methyl-2-Pyrone, InChI=1/C6H6O3/c1-4-2-5(7)3-6(8)9-4/h2-3,7H,1H


ID: 1518

chemical graph of compound 1518



InChIKey: NTAHJPYHXKMYBL-UHFFFAOYSA-N
SMILES: CCOC1=CC=C(C=C1)C(=O)C2=C(C(=C(C=C2)OC)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6728940
synonyms found at PubChem are:
2,3-DIHYDROXY-4-METHOXY-4'-ETHOXYBENZOPHENONE, SPBio_000200, AC1O9ATO, Spectrum2_000290, SPECTRUM200425, SCHEMBL4007549, CHEMBL1371413, CCG-39848, SDCCGMLS-0066436.P001, NCGC00095475-01, SR-05000002547, SR-05000002547-1, (2,3-dihydroxy-4-methoxyphenyl)-(4-ethoxyphenyl)methanone


ID: 1519

chemical graph of compound 1519



InChIKey: NTHXOOBQLCIOLC-UHFFFAOYSA-N
SMILES: CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3730
synonyms found at PubChem are:
iohexol, 66108-95-0, Nycodenz, Omnipaque, Exypaque, Iohexolum, Omnipaque 240, Histodenz, Iohexolum [INN-Latin], EINECS 266-164-2, WIN 39424, BRN 2406632, N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide, CHEBI:31709, NTHXOOBQLCIOLC-UHFFFAOYSA-N, NCGC00166000-01, DSSTox_CID_3157, 5-(N-2,3-Dihydroxypropylacetamido)-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide, DSSTox_RID_76895, DSSTox_GSID_23157, 1,3-Benzenedicarboxamide, 5-(acetyl(2,3-dihydroxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-, Omnipaque 70, 5-(N-2-3-DIHYDROXYPROPYL-ACETMIDO)-2,4,6-TRIIODO-N,N'-bis-(2,3-DIHYDROXYPROPYL)-ISOPHTHALAMIDE, 5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, 5-[N-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide, SMR000857075, Omnipaque 180, Omnipaque 210, Imaginil, Oxilan iohexol, Histodenz&trade;, Iohexol [USAN:BAN:INN:JAN], C19H26I3N3O9, Omnipaque (TN), 1,3-benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-, n,n'-bis(2,3-dihydroxypropyl)-5-[n-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide, Prestwick_802, Imagenil 300, Imagenil 350, CAS-66108-95-0, Iohexol [USAN:USP:INN:BAN:JAN], Histodenz|||Nycodenz, AC1L1GKZ, Prestwick0_000512, Prestwick1_000512, Prestwick2_000512, Prestwick3_000512, D02BLO, EC 266-164-2, Iohexol injection (JP17), Iohexol, analytical standard, SCHEMBL26501, BSPBio_000463, MLS001332585, MLS001332586, MLS002153854, Iohexol (JP17/USP/INN), SPBio_002384, BPBio1_000511, CHEMBL1200455, DTXSID6023157, BCBcMAP01_000051, CTK8G0334, MolPort-003-931-371, HMS1569H05, HMS2096H05, HMS2235D07, HMS3369O04, HMS3713H05, ALBB-028959, EBD45459, HY-B0594, KS-00001F7T, ZX-AN079772, Tox21_112286, WIN-39424, AKOS015895399, Tox21_112286_1, AC-1934, API0003012, CCG-220512, CS-2811, DB01362, SMP1_000152, NCGC00166000-02, NCGC00166000-04, AN-14471, AS-12699, BC209326, CC-29572, LS-29715, SC-17734, AB0012347, FT-0627276, I0903, D01817, Histodenz(TM), nonionic density gradient medium, 108I950, A835339, C-23546, SR-01000838892, I06-0659, SR-01000838892-2, Iohexol, European Pharmacopoeia (EP) Reference Standard, Iohexol, United States Pharmacopeia (USP) Reference Standard, 5-(N-dhp-acetamido)-2,4,6-triiodo-N,N'-B is-dhp-isophthalami, Iohexol for peak identification, European Pharmacopoeia (EP) Reference Standard, 1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-, 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide, 5-(N-2,3-Dihydroxypropylacetamido)-2,4,6-triiodo-N,N inverted exclamation marka-bis(2,3-dihydroxypropyl)isophthalamide, 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-benzene-1,3-dicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, 5-[n-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamidesolution, IOX, N1,N3-bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide, N1,N3-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide, N1,N3-bis[2,3-bis(oxidanyl)propyl]-5-[2,3-bis(oxidanyl)propyl-ethanoyl-amino]-2,4,6-tris(iodanyl)benzene-1,3-dicarboxamide


ID: 1520

chemical graph of compound 1520



InChIKey: NUHPODZZKHQQET-UHFFFAOYSA-N
SMILES: CC1CC(=O)NN=C1C2=CC=C(C=C2)NC(=NC)NC#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 72124
synonyms found at PubChem are:
Siguazodan, 115344-47-3, SKF 94836, SKF-94836, SkF94836, C14H16N6O, SK&F 94836, NCGC00015947-02, DSSTox_CID_25202, DSSTox_RID_80746, DSSTox_GSID_45202, 2-Cyano-1-methyl-3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)guanidine, N-Cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine, Guanidine,N-cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-, CAS-115344-47-3, Siguazodan [BAN:INN], Siguazodan [INN:BAN], SR-01000075284, ACMC-20bv5x, AC1L2HGM, AC1Q6LMW, D0Q7VI, Lopac0_000997, BSPBio_001354, KBioGR_000074, KBioSS_000074, SCHEMBL149133, CHEMBL1256712, DTXSID0045202, SCHEMBL12648714, SCHEMBL18522869, CHEBI:91791, CTK4A9290, KBio2_000074, KBio2_002642, KBio2_005210, KBio3_000147, KBio3_000148, MolPort-003-959-538, NUHPODZZKHQQET-UHFFFAOYSA-N, Bio2_000074, Bio2_000554, HMS1361D16, HMS1791D16, HMS1989D16, HMS2090J18, HMS3267B05, HMS3402D16, Tox21_110264, AKOS024456417, Tox21_110264_1, CCG-205077, SK&F-94836, 1-cyano-3-methyl-2-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]guanidine, IDI1_033824, SMP2_000276, NCGC00015947-03, NCGC00015947-04, NCGC00015947-05, NCGC00015947-06, NCGC00015947-07, NCGC00015947-08, NCGC00025032-02, NCGC00025032-03, NCGC00025032-04, NCGC00025032-05, NCGC00025032-06, LS-172289, RT-015699, EU-0100997, FT-0631077, S 3317, AB01275530-01, C-17907, J-003284, SR-01000075284-1, SR-01000075284-3, BRD-A62071884-001-03-8, BRD-A91992993-001-01-2, 1-cyano-2-methyl-3-[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]guanidine, 2-cyano-1-methyl-3-(4-(methyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-yl)phenyl)guanidine, 6-[4-(N3 -Methyl-N2 -cyanoguanidino)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone, N-Cyano-N inverted exclamation marka-methyl-N inverted exclamation marka-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine, N-Cyano-N'-methyl-N''-[4-[(1,4,5,6-tetrahydro-4-methyl-6-oxopyridazin)-3alpha-yl]phenyl]guanidine


ID: 1521

chemical graph of compound 1521



InChIKey: NUKYPUAOHBNCPY-UHFFFAOYSA-N
SMILES: C1=CN=CC=C1N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 1727
synonyms found at PubChem are:
4-aminopyridine, 504-24-5, pyridin-4-amine, 4-Pyridinamine, Fampridine, Dalfampridine, 4-Pyridylamine, Avitrol, p-Aminopyridine, 4-AP, Ampyra, gamma-Aminopyridine, Pyridine, 4-amino-, Amino-4 pyridine, Avitrol 200, Pimadin (free base), Compound 1861, Phillips 1861, Fampridine-SR, FAMPYRA, Amaya, 4 Aminopyridine, Prc 1237, VMI 10-3, Caswell No. 038, Neurelan, VMI-103, 4-amino-pyridine, UNII-BH3B64OKL9, 4- Aminopyridine, pyridin-4-ylamine, Amino-4-Pyridine, Mi-W-3, EL-970, NSC 15041, Ampyra (TN), .gamma.-Aminopyridine, 4(1H)-Pyridinimine, HSDB 6037, 4-AMINOPYRDINE, EINECS 207-987-9, RCRA waste no. P008, EPA Pesticide Chemical Code 069201, BRN 0105782, BH3B64OKL9, AI3-52547, MLS000069400, C5H6N2, CHEMBL284348, CHEBI:34385, N07XX07, NUKYPUAOHBNCPY-UHFFFAOYSA-N, NCGC00015009-08, A106, SMR000058211, DSSTox_CID_3870, DSSTox_RID_77212, DSSTox_GSID_23870, Pymadine, 29212-32-6, CAS-504-24-5, VMI 103, SR-01000075299, 4AP, Fampridine [USAN:INN], Dalfampridine [USAN:INN], fampridina, fampridinum, Frampridine, Ampydin, BIIB041, Pymadin, BIIB 041, Fampridine-PR, Dalfampridine-ER, 4-pyridyl amine, 4-amino pyridine, pyridine-4-amine, 3rxf, Neurelan (TN), pyridine-4-ylamine, Fampridine [INN], Fampyra (TN), pyridin-4-yl-amine, 4-Aminopyridine 10, PubChem1281, Philips 1861, Dalfampridine (USAN), Spectrum_000155, Tocris-0940, Fampridine (JAN/INN), 4-Aminopyridine, 98%, PYRIDINE,4-AMINO, Opera_ID_1768, Spectrum2_001413, Spectrum3_000914, Spectrum4_001013, Spectrum5_001501, Lopac-A-0152, D08YIN, UPCMLD-DP125, WLN: T6NJ DZ, 4-Pyridinamine; Fampridine, AC1L1C3R, AC1Q52BM, 4-Aminopyridine, >=99%, Lopac0_000032, BSPBio_001562, KBioGR_000282, KBioGR_001505, KBioSS_000282, KBioSS_000635, 4-imino-1,4-dihydropyridine, 5-22-09-00106 (Beilstein Handbook Reference), ARONIS25052, DivK1c_000572, SPECTRUM1501130, SPBio_001486, 4 AP, BIIB-041, GTPL2416, 4-Pyridinamine, 4-Pyridylamine, 4-Aminopyridine, 98% 50g, CL-COB-III-274-1, DTXSID0023870, UPCMLD-DP125:001, AMPD00207, BDBM10458, CTK0J1462, HMS501M14, KBio1_000572, KBio2_000282, KBio2_000635, KBio2_002850, KBio2_003203, KBio2_005418, KBio2_005771, KBio3_000563, KBio3_000564, KBio3_001888, MolPort-000-146-022, NINDS_000572, Bio1_000353, Bio1_000842, Bio1_001331, Bio2_000282, Bio2_000762, HMS1361O04, HMS1791O04, HMS1921H15, HMS1989O04, HMS2092F05, HMS2234N24, HMS3260G05, HMS3267E21, HMS3370J03, HMS3402O04, KUC111877N, Pharmakon1600-01501130, ZINC599985, ACT05167, HY-B0604, KS-000046YS, NSC15041, VMI-10-3, Tox21_110065, Tox21_200793, Tox21_500032, ANW-75388, BBL009925, CCG-39031, HTS004685, MFCD00006439, NSC-15041, NSC757845, RB8003, RW2023, SBB004393, STK298717, AKOS000119896, p-Aminopyridine [UN2671] [Poison], Tox21_110065_1, BS-3729, CS-2822, DB06637, LP00032, LS20499, MCULE-6604546217, NSC-757845, QC-4324, RP18049, SDCCGMLS-0066228.P001, VP10051, IDI1_000572, IDI1_034032, KS-0000057B, p-Aminopyridine [UN2671] [Poison], NCGC00015009-01, NCGC00015009-02, NCGC00015009-03, NCGC00015009-04, NCGC00015009-05, NCGC00015009-06, NCGC00015009-07, NCGC00015009-09, NCGC00015009-10, NCGC00015009-11, NCGC00015009-12, NCGC00015009-13, NCGC00015009-14, NCGC00015009-16, NCGC00024890-01, NCGC00024890-02, NCGC00024890-03, NCGC00024890-04, NCGC00024890-05, NCGC00024890-06, NCGC00024890-07, NCGC00024890-08, NCGC00024890-09, NCGC00024890-10, NCGC00258347-01, NCGC00260717-01, AN-45400, BC227053, BP-21343, HC150041, KB-36586, SC-04870, SBI-0050021.P003, AB1004971, DB-028705, LS-130202, TC-063856, TC-164133, TL8003344, A0414, AM20061261, B3530, EU-0100032, FT-0083754, FT-0617606, ST45053817, AZ0001-0464, A 0152, C13728, D04127, M-6065, 68146-EP2269990A1, 68146-EP2284157A1, 68146-EP2289894A2, 68146-EP2298731A1, 68146-EP2308874A1, 68146-EP2380872A1, 79676-EP2305695A2, 79676-EP2305696A2, 79676-EP2305697A2, 79676-EP2305698A2, AB00052209_12, [J.Pharmacol.Exp.Ther. 275:864 (1995)], 4-Aminopyridine, PESTANAL(R), analytical standard, Q-200436, SR-01000075299-1, SR-01000075299-3, SR-01000075299-5, F2190-0487, Z955123498, Dalfampridine, United States Pharmacopeia (USP) Reference Standard, InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7


ID: 1522

chemical graph of compound 1522



InChIKey: NUZWLKWWNNJHPT-UHFFFAOYSA-N
SMILES: C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=CC=C3O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2202
synonyms found at PubChem are:
anthralin, Dithranol, 1143-38-0, 1,8-Dihydroxyanthrone, 1,8-Dihydroxy-9-anthrone, Chrysodermol, Cigthranol, Cignolin, 1,8-Dihydroxyanthracen-9(10H)-one, Batridol, Psoriacid-Stift, 9(10H)-Anthracenone, 1,8-dihydroxy-, Anthra-Derm, Drithoscalp, DrithoCreme, Anthrone, 1,8-dihydroxy-, NSC 43970, 1,8-dihydroxy-10H-anthracen-9-one, 1,8-DIHYDROXY-9(10H)-ANTHRACENONE, Anthraline, NSC 629313, UNII-U8CJK0JH5M, Dithranolum [INN-Latin], Anthralin [USP], CCRIS 628, CHEBI:37510, 1,8 Dihydroxyanthrone, EINECS 214-538-0, U8CJK0JH5M, BRN 2054360, CHEMBL46469, NUZWLKWWNNJHPT-UHFFFAOYSA-N, Anthralin (USP), Dithranol (INN), Dithranol [INN], NSC629313, NCGC00091330-01, DSSTox_CID_4538, 1,8-Dihydroxy-9(10H)-anthracenone;Anthralin, DSSTox_RID_77448, DSSTox_GSID_24538, W-108602, Dithranolum, Zithranol-RR, CAS-1143-38-0, SR-05000002011, Psodadrate, Prestwick_528, Anthralin, Dithranol, Dithranol ,(S), Anthralin (Dithranol), Anthrone,8-dihydroxy-, Spectrum_000056, ANTHRADERM (TN), Spectrum2_000111, Spectrum3_000304, Spectrum4_000151, Spectrum5_000820, Epitope ID:114081, 1,8-dihydroxy-9-anthrane, AC1L1D5I, cid_2202, SCHEMBL3197, BSPBio_001868, KBioGR_000622, KBioSS_000436, MLS001332632, MLS002415712, DivK1c_000021, SPECTRUM1500127, SPBio_000122, AC1Q794G, ZINC1322, Dithranol, >=90% (HPLC), DTXSID7024538, CTK8A0163, HMS500B03, KBio1_000021, KBio2_000436, KBio2_003004, KBio2_005572, KBio3_001368, NUZWLKWWNNJHPT-UHFFFAOYSA-, MolPort-001-792-502, NINDS_000021, HMS1920E07, HMS2091K07, HMS2271B09, HMS3715H19, Pharmakon1600-01500127, HY-B0738, NSC43970, 9(10H)-Anthracenone,8-dihydroxy-, Tox21_111115, Tox21_201851, Tox21_300290, BDBM50041802, CCG-38920, LS-570, MFCD00053409, NSC-43970, NSC755873, 1,8-dihydroxy-9-(10H)anthracenone, AKOS015914122, Tox21_111115_1, API0002431, CS-2980, DB11157, KS-5183, MCULE-8492759735, NSC-629313, NSC-755873, 1,8-dihydroxy-10-hydroanthracen-9-one, IDI1_000021, 1,8-Dihydroxy-9(10H)-anthracenone #, NCGC00091330-02, NCGC00091330-03, NCGC00091330-04, NCGC00091330-05, NCGC00091330-07, NCGC00253941-01, NCGC00259400-01, AC-14842, AJ-08003, AK481321, AN-20615, CJ-00043, NCI60_004019, SC-19051, SBI-0051286.P003, AB0105711, FT-0625372, ST50825759, C06831, D00233, K-1044, 9(10H)-Anthracenone, 1,8-dihydroxy- (9CI), AB00051916_07, SR-05000002011-1, SR-05000002011-2, I14-44798, Dithranol, European Pharmacopoeia (EP) Reference Standard, Anthralin, United States Pharmacopeia (USP) Reference Standard, Anthralin (Dithranol), Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2


ID: 1523

chemical graph of compound 1523



InChIKey: NVEQFIOZRFFVFW-RGCMKSIDSA-N
SMILES: C[C@@]12CC[C@@H]3[C@H](CC3(C)C)C(=C)CC[C@H]1O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 1742210
synonyms found at PubChem are:
Caryophyllene oxide, 1139-30-6, (-)-Caryophyllene oxide, beta-Caryophyllene epoxide, beta-Caryophyllene oxide, (-)-Epoxycaryophyllene, UNII-S2XU9K448U, (-)Carophyllene oxide, Caryophyllene epoxide, CHEMBL508894, S2XU9K448U, Epoxycaryophyllene, CHEBI:67818, trans-caryophyllene oxide, HSDB 5466, EINECS 214-519-7, (1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.04,6]dodecane, 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-Trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane, (1R,4R,6R,10S)-, 5-Oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-, ()-Caryophyllene oxide, trimethyl(methylene)[?], AC1LX0JS, DSSTox_CID_30138, DSSTox_GSID_51586, SCHEMBL127077, DTXSID4051586, (-)-Caryophyllene oxide, 95%, CTK8F1397, MolPort-003-927-963, (1R-(1R*,4R*,6R*,10S*))-4,12,12-Trimethyl-9-methylene-5-oxatricyclo(8.2.0.04,6)dodecane, 5-Oxatricyclo(8.2.0.0(sup 4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-, ZINC2083320, Tox21_303807, BDBM50241720, MFCD00134216, AKOS030241571, CCG-208462, NCGC00357089-01, CAS-1139-30-6, W2222, C16908, SR-05000002236, SR-05000002236-2, W-108611, (-)-Caryophyllene oxide, analytical reference material, (1R,4R,5R,9S)-4,5-epoxycaryophyllan-8(13)-ene, (-)-Caryophyllene oxide, >=99.0% (sum of enantiomers, GC), Caryophyllene Oxide Solution, 1000 mg/L, 1 ml (RM, ISO GUIDE 34), (1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.0(4,6])dodecane, 5-Oxatricyclo[8.2.0.04,6]dodecane,4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-, 105120-46-5, 11023-55-5, 32095-03-7, 52209-95-7


ID: 1524

chemical graph of compound 1524



InChIKey: NVGOUBIJVPSVSL-UHFFFAOYSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)C2=C(N(C(=O)C3=C2C=CC(=C3)OCC4=CC=CC=N4)C5=CC=C(C=C5)N)C(=O)OC.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 9874535
synonyms found at PubChem are:
t-1032, CHEMBL77971, UNII-H68FTS7316, H68FTS7316, SCHEMBL1148164, NCGC00094482-01, LS-85432, EU-0101241, T 7692, SR-01000076176, SR-01000076176-1, 212500-03-3, 3-Isoquinolinecarboxylic acid, 2-(4-aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-, methyl ester, sulfate (1:1), Methyl (2-(4-aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinoline carboxylate sulfate


ID: 1525

chemical graph of compound 1525



InChIKey: NVMIBYLXLVBCEV-UHFFFAOYSA-N
SMILES: CC1=NC(=NC2=C1C=CC(=C2)OC)NC3=NC(=O)C=C(N3)C4=CC=CC=C4

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"O Zegarra-Moran" "GL Lukacs" "AS Verkman" "E Caci" "N Pedemonte" "K Du" "LJ Galietta"


CID is 1002841
synonyms found at PubChem are:
MLS000777862, SMR000414248, 2-[(7-methoxy-4-methylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol, 2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-6-phenyl-pyrimidin-4-ol, 2-[(7-methoxy-4-methylquinazolin-2-yl)amino]-6-phenyl-1H-pyrimidin-4-one, ChemDiv1_003480, AC1LJM74, Oprea1_047289, Oprea1_372553, SCHEMBL837873, CHEMBL1565526, BDBM54369, cid_1002841, HMS596O04, MolPort-000-400-930, MolPort-000-783-773, NVMIBYLXLVBCEV-UHFFFAOYSA-N, HMS2756K04, STK087243, STL436005, ZINC18117526, AKOS001711415, AKOS002821881, CCG-121222, MCULE-9742179113, AB00132382-08, SR-01000431115, SR-01000431115-1, 2-(7-Methoxy-4-methylquinazolin-2-ylamino)-6-phenylpyrimidin-4-ol, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-6-phenyl-1H-pyrimidin-4-one, 2-[(7-methoxy-4-methyl-quinazolin-2-yl)amino]-6-phenyl-1H-pyrimidin-4-one


ID: 1526

chemical graph of compound 1526



InChIKey: NVUGEQAEQJTCIX-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CNC2=CC=CC=C21

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 70547
synonyms found at PubChem are:
N-Acetyltryptamine, 1016-47-3, N-(2-(1H-indol-3-yl)ethyl)acetamide, N-[2-(1H-Indol-3-yl)ethyl]acetamide, 3-(2-N-Acetylaminoethyl)indole, Acetamide, N-[2-(1H-indol-3-yl)ethyl]-, CHEMBL33171, CHEBI:55515, NVUGEQAEQJTCIX-UHFFFAOYSA-N, N-[2-(1H-Indol-3-yl)-ethyl]-acetamide, Acetamide, N-(2-(1H-indol-3-yl)ethyl)-, SMR000686036, SR-01000075685, Acetotryptamide, Acetamide, N-(2-indol-3-ylethyl)-, Tocris-0357, AC1L2EBK, Lopac-A-7342, N-Acetyltryptamine, powder, AC1Q1L6A, 3-(2-Acetamidoethyl)indole, Lopac0_000101, MLS001250169, MLS002153204, SCHEMBL468850, AC1Q5P72, ISUPSL100255, ACon1_000465, CTK8G1571, N-(2-indol-3-ylethyl)acetamide, DTXSID30144042, MolPort-001-739-474, HMS2270O21, HMS3260E04, HMS3266I05, ZINC174849, KS-000017TN, Tox21_500101, 0428AA, BDBM50282758, MFCD00209910, PDSP1_001815, PDSP2_001798, STL352108, AKOS000639631, API0008397, CCG-204196, LP00101, MCULE-3484861085, NCGC00015088-01, NCGC00015088-02, NCGC00015088-03, NCGC00015088-04, NCGC00015088-05, NCGC00015088-06, NCGC00015088-07, NCGC00015088-08, NCGC00015088-09, NCGC00024552-01, NCGC00024552-02, NCGC00024552-03, NCGC00024552-04, NCGC00024552-05, NCGC00024552-06, NCGC00260786-01, AJ-17612, ZB009323, N-[2-(1H-Indol-3-yl)ethyl]acetamide #, AX8143076, KB-103425, B6274, EU-0033445, EU-0100101, ST50409166, A 7342, EN300-189721, Acetamide, N-(2-indol-3-ylethyl)- (7CI,8CI), Acetotryptamide N-Acetyl-2-(indol-3-yl)ethylamine, Acetamide, N-[2-(1H-indol-3-yl)ethyl]- (9CI), J-000457, SR-01000075685-1, SR-01000075685-2, SR-01000075685-4, BRD-K73700643-001-04-7, BRD-K73700643-001-10-4, NCGC00015088-09_C12H14N2O_N-[2-(1H-Indol-3-yl)ethyl]acetamide, 374572-55-1, 7AN


ID: 1527

chemical graph of compound 1527



InChIKey: NWBJYWHLCVSVIJ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 62389
synonyms found at PubChem are:
6-Benzylaminopurine, 1214-39-7, Benzyladenine, N6-Benzyladenine, N-Benzyl-9H-purin-6-amine, N-Benzyladenine, 6-Benzyladenine, 6-(Benzylamino)purine, Cytokinin B, Adenine, N-benzyl-, 6-BAP, N(6)-Benzylaminopurine, N-benzyl-7H-purin-6-amine, Aminopurine, 6-benzyl, BA (Growth stimulant), Pro-Shear, BAP (growth stimulant), N(sup 6)-Benzyladenine, 6-Benzyl adenine, Benzyl(purin-6-yl)amine, 6-(N-Benzylamino)purine, N-6-Benzyladenine, Verdan senescence inhibitor, 1H-PURIN-6-AMINE, N-(PHENYLMETHYL)-, N-(Phenylmethyl)-1H-purin-6-amine, 6-BA, N(sup 6)-(Benzylamino)purine, Caswell No. 081EE, N(6)-(benzylamino)purine, UNII-KXG6A989PS, Adenine, N(sup 6)-benzyl-, SD 4901, SQ 4609, CCRIS 4351, benzylpurin-6-ylamine, 6-(n-benzyl)aminopurine, ABG 3034, 6-[(phenylmethyl)amino]-9H-purine, EINECS 214-927-5, NSC 40818, EPA Pesticide Chemical Code 116901, 6-(Benzylamino)-9H-purine, KXG6A989PS, N-benzyl-1H-purin-6-amine, MLS000532693, CHEMBL228862, benzyl-(7h-purin-6-yl)-amine, CHEBI:29022, NWBJYWHLCVSVIJ-UHFFFAOYSA-N, n(6)-benzyladenine, n6-benzylaminopurine, 9H-Purin-6-amine, N-(phenylmethyl)-, benzylaminopurine, 6-, SMR000140130, CAS-1214-39-7, 6-benzyladenine 6-benzylaminopurine, Benzyl adenine, HSDB 7667, N-Benzyl-adenine, Benzyl Aminopurine, BAP (cytokinin), N6 -Benzyladenine, ((2r,3s,4r,5r)-5-(4-amino-2-oxopyrimidin-1(2h)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyltriphosph, Prestwick_414, 6-benzylamino purine, PubChem9266, Adenine, N6-benzyl-, 6-Benzylaminopurine;BA, N-Benzyladenine, 8CI, N(Sup6)-Benzyladenine, BA (growth stimulator), ACMC-1CACB, Opera_ID_868, Prestwick0_000189, Prestwick1_000189, Prestwick2_000189, Prestwick3_000189, N(Sup 6)-benzyl-Adenine, CBKinase1_000521, CBKinase1_012921, AC1Q28ZG, Cambridge id 5131951, TimTec1_001722, DSSTox_CID_12630, DSSTox_RID_79014, DSSTox_GSID_32630, Oprea1_747691, Oprea1_785203, Oprea1_830563, SCHEMBL35562, BSPBio_000117, CBDivE_001815, MLS001074298, 6-Benzyladenine, 99% 1g, N6-benzyl-9H-purin-6-amine, SPBio_002038, 6-Benzylaminopurine, 99.0%, AC1L1X11, AC1Q290J, BPBio1_000129, DTXSID7032630, CTK4D1317, CTK5J6355, NWBJYWHLCVSVIJ-UHFFFAOYSA-, ZINC43479, MolPort-000-159-363, MolPort-001-813-199, HMS1538O06, HMS1568F19, HMS1667I06, HMS2095F19, HMS2234B24, HMS3374C09, HMS3712F19, HY-B0941, NSC40818, STR06184, 6-Benzylaminopurine; Benzyl Kinetin, N-(phenylmethyl)-7H-purin-6-amine, Tox21_301307, ANW-17632, BDBM50205363, CCG-55533, GEO-00296, MFCD00005572, N-(Phenylmethyl)-9H-Purin-6-amine, NSC-40818, s4511, STK858495, AKOS002304241, AKOS005257767, AKOS028109211, 7H-purin-6-amine, N-(phenylmethyl)-, AC-5488, AM84356, CCG-220189, KS-5285, LS40236, MCULE-1256228871, PS-3425, RP17542, TRA0001883, 6-Benzylaminopurine, analytical standard, KS-00000A54, N-benzyl-9H-purin-6-amine, AldrichCPR, NCGC00016571-01, NCGC00016571-02, NCGC00016571-03, NCGC00016571-04, NCGC00016571-05, NCGC00255357-01, AJ-09003, AN-10971, BR-47425, KB-82016, LS-15063, SC-00593, ST020598, SY014632, ZB001335, 6-Benzylaminopurine, >=99.0% (HPLC), KB-199069, KB-199071, TC-106377, TL8000571, B1088, FT-0620956, ST24033089, EN300-40176, 14B397, 6-Benzylaminopurine, plant cell culture tested, B-1000, C11263, M-4965, SR-01000644553, 6-Benzylaminopurine, Vetec(TM) reagent grade, 98%, I01-0020, SR-01000644553-1, SR-01000644553-2, BA ; N6-Benzyladenine ; N6-Benzyladenine ; BA, BRD-K62929068-001-05-8, BRD-K62929068-001-15-7, I14-15079, 6-Benzylaminopurine, ReagentPlus(R), >=99.0% (HPLC), F0578-0089, 2B76FFBD-3C3A-4349-9047-E5B8945B54A7, 9H-Purin-6-amine,N-(phenylmethyl)-, hydrochloride (1:1), 6-Benzylaminopurine solution, 1 mg/mL, plant cell culture tested, 124786-41-0, 3458-19-3, InChI=1/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)


ID: 1528

chemical graph of compound 1528



InChIKey: NWCRHCHMUBHHPO-UDWIEESQSA-N
SMILES: Cc1ccc(s1)c2cc(n[nH]2)C(=O)N/N=C(\C)/c3ccc(c(c3)OC)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Park" "AS Verkman" "W Namkung" "Y Seo"


CID is 5445606
synonyms found at PubChem are:
AC1NU4WY, MolPort-000-715-177, MolPort-001-805-079, STL024943, ZINC12462536, AKOS005641880, AKOS027282597, N'-(1-(3,4-DI-MEO-PH)ETHYLIDENE)-3-(5-ME-2-THIENYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE, 1299325-63-5, N'-[(1E)-1-(3,4-dimethoxyphenyl)ethylidene]-3-(5-methylthiophen-2-yl)-1H-pyrazole-5-carbohydrazide, N-[(E)-1-(3,4-dimethoxyphenyl)ethylideneamino]-5-(5-methylthiophen-2-yl)-1H-pyrazole-3-carboxamide


ID: 1529

chemical graph of compound 1529



InChIKey: NWIBSHFKIJFRCO-WUDYKRTCSA-N
SMILES: CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5746
synonyms found at PubChem are:
mitomycin C, Mitomycin, 50-07-7, Ametycine, Mutamycin, Mitocin-C, Ametycin, Mitomycin-C, Mitomycinum, Mytomycin, Mytozytrex, Mitozytrex, Mitomycinum C, Mitocin C, Mitomycins, Mitamycin, MMC, Mitosol, 7-Amino-9alpha-methoxymitosane, Mitomycyna C, NSC-26980, Mitomycyna C [Polish], Mito-C, Mit-C, Mitomicina, Mitomycine, Mitomycin (TN), Mitomycine [INN-French], Mitomycinum [INN-Latin], Mitomicina [INN-Spanish], Muamycin, NCI-C04706, RCRA waste number U010, NSC26980, NSC 26980, Muamycin (TN), CCRIS 414, Mitomycin [USAN:INN:BAN], UNII-50SG953SK6, HSDB 3239, C15H18N4O5, Mitomycin (USP/INN), EINECS 200-008-6, Mitomycin C, Streptomyces caespitosus, RCRA waste no. U010, AI3-26199, CHEBI:27504, 50SG953SK6, Mitomycin C, Streptomyces caespitosus, Carrier-Free, Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-, Mitomycin C from Streptomyces caespitosus, Mitomycin C (JP15), DSSTox_CID_898, DSSTox_RID_75853, DSSTox_GSID_20898, 6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione carbamate (ester), Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-, CAS-50-07-7, ((1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate, [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methyl-, carbamate (ester), Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-, Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aS-(1aalpha,8beta,8aalpha,8balpha)]-, MLS002702984, (amino-methoxy-methyl-dioxo-[?]yl)methyl carbamate, 7-Amino-9.alpha.-methoxymitosane, Mitomycin [USAN:USP:INN:BAN], NCGC00095258-01, [(1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2'',3'':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, 7-Amino-9&alpha, Mitomycin C (JP17), CHEMBL105, D0NZ1U, D0Y0GH, AC1L1L1Q, SCHEMBL3760, CBiol_001927, BSPBio_001267, KBioGR_000607, KBioSS_000607, 1404-00-8, MLS001332654, Mitozytrex (TN) (Supergene), AMETYCIN pound notmitomycin C, GTPL7089, DTXSID2020898, KBio2_000607, KBio2_003175, KBio2_005743, KBio3_001073, KBio3_001074, EX-A501, MolPort-003-938-644, NWIBSHFKIJFRCO-WUDYKRTCSA-N, ZX-AFC000411, BCPP000410, Bio1_000213, Bio1_000702, Bio1_001191, Bio2_000464, Bio2_000944, HMS1362O09, HMS1792O09, HMS1990O09, HMS2089F16, HMS3403O09, Tox21_111493, BDBM50428658, GR-311, LS-136, MFCD00078109, s8146, ZINC30726187, AKOS015895703, Tox21_111493_1, ACN-038344, BCP9000285, CCG-208564, CS-0564, DB00305, KS-5148, IDI1_002219, SMP1_000307, NCGC00163468-02, NCGC00163468-03, NCGC00163468-05, NCGC00163468-06, AN-15420, Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))- (9CI), BC208285, CC-30970, HY-13316, SC-17000, SMR000058401, BCP0726000181, KB-145809, LS-173087, M2320, C06681, D00208, W-5071, AB00918689-03, AB00918689-04, 078M109, C-20147, Mitomycin C, Antibiotic for Culture Media Use Only, Q-201410, BRD-K59670716-001-02-6, BRD-K59670716-001-06-7, UNII-V03E10691T component NWIBSHFKIJFRCO-WUDYKRTCSA-N, WLN: T D3 B556 BN EM JV MVTTT&J GO1 H1OVZ KZ L1, Mitomycin C from Streptomyces caespitosus, >=970 mug/mg (USP XXIV), Mitomycin C from Streptomyces caespitosus, powder, BioReagent, suitable for cell culture, Mitomycin C from Streptomyces caespitosus, powder, contains NaCl as solubilizer, (1ar)-6-amino-8-(((aminoc arbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, (1ar)-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0;{2,7}.0;{4,6}]trideca-1(9),11-dien-8-yl]methyl carbamate, [1aR-(1aalpha,8beta,8aalpha,8balpha)]-6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-alpha]indole-4,7-dione, [1aS-(1a?,8?,8a?,8b?)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, [1aS-(1aalpha,8beta,8aalpha,8balpha)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 144085-53-0, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino[2',3':3, 4]pyrrolo[1,2-a]indole-4,7-dione, carbamate (ester), 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, carbamate (ester), 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl, [1aS-(1aalpha,8beta,8aalpha,8balpha)]-azirino[2',3':3,4]pyrrol o[1,2a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl, [1aS-(1aalpha,8beta,8aalpha,8balpha)]-azirino[2',3':3,4]pyrrolo[1,2a]indole-4,7-dione, 74349-48-7, 7481-68-7, Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl -, [1aS-(1aalpha,8beta,8aalpha,8balpha)]-, Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-5-methyl-, carbamate (ester), Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methyl-, [1aR-(1a.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-, Mitomycin C from Streptomyces caespitosus, >=98% (HPLC), potency: >=970 mug per mg (USP XXIV), gamma-irradiated, suitable for cell culture


ID: 1530

chemical graph of compound 1530



InChIKey: NWNVDSJZGYDVQW-UHFFFAOYSA-N
SMILES: CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 22543
synonyms found at PubChem are:
PROTOPINE HYDROCHLORIDE, 6164-47-2, Protopine HCl, UNII-96481YJ70G, HSDB 3556, EINECS 228-196-5, NSC 11440, C20H19NO5.HCl, NSC11440, 96481YJ70G, Fumarine hydrochloride, 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride, Bis(1,3)benzodioxolo(4,5-C:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride, Protopine, hydrochloride, AC1L2KKT, ARGEMONINE (PROTOPINE, SCHEMBL4456077, 130-86-9 (Parent), CHEMBL2165579, CTK8G2642, DTXSID70210654, MolPort-004-824-728, 8223AH, MFCD00236406, NSC-11440, Protopine hydrochloride, >=98%, solid, LS-125891, 7, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride, 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-, hydrochloride (8CI), Bis[1,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride, Bis(1,3)benzodioxolo(4,5-c:5',6'-g)azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-, hydrochloride (9CI), 7-methyl-6,8,9,16-tetrahydrobis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one hydrochloride, bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-15(7H)-one, 6,8,9,16-tetrahydro-7-methyl-, hydrochloride


ID: 1531

chemical graph of compound 1531



InChIKey: NWPRCRWQMGIBOT-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 1892
synonyms found at PubChem are:
ETOFYLLINE, 519-37-9, 7-(2-Hydroxyethyl)theophylline, Aethophyllinum, Cordalin, Oxyphylline, Ascorphylline, Dilaphyllin, Oxytheonyl, Oxyethyltheophylline, Frekaphyllin, Sklerodormal, Soluphylline, Bio-phylline, Phyllocormin N, Corophyllin-N, Oxphylline (amido), 1,3-Dimethyl-7-(2-hydroxyethyl)xanthine, Oxyetophyllinum, 7-Theophyllineethanol, 7-(Hydroxyethyl)theophylline, Hydroxyethyl theophylline, Theophylline, 7-(2-hydroxyethyl)-, 7-hydroxyethyltheophylline, Oxyaethyltheophyllin, Etofillina [DCIT], etophylline, Hydroxyethyltheophylline, Oxphylline, Etofylline [INN:BAN], Etofilina [INN-Spanish], Etofyllinum [INN-Latin], 7-(2-Hydroxyethyl)-1,3-dimethylxanthine, beta-hydroxyethyltheophylline, Oxyaethyltheophyllin [German], NSC 113373, UNII-L164909TBI, C9H12N4O3, BETA-HYDROXYETHYL THEOPHYLLINE, EINECS 208-269-8, 7-(2-Hydroxyethyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, CHEMBL699, 7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione, BRN 0251760, 7-(2-hydroxyethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, MLS000115542, 7-(2'-Hydroxyethyl)theophylline, NWPRCRWQMGIBOT-UHFFFAOYSA-N, L164909TBI, 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-, 7-(.beta.-Hydroxyethyl)theophylline, NCGC00016479-06, 7-(beta-HYDROXYETHYL)-THEOPHYLLINE, CAS-519-37-9, SMR000058179, 3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione, 7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, DSSTox_CID_3031, DSSTox_RID_76839, DSSTox_GSID_23031, Etofillina, Etofyllinum, Etofilina, etophyllin, oxyethophylline, Oxyphyllin, 7-(2-hydroxyethyl)-1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, Oxyphyllin (TN), Etofylline (INN), Prestwick_210, Spectrum_000319, ACMC-209kws, Opera_ID_628, AC1L1CGR, Prestwick0_000172, Prestwick1_000172, Prestwick2_000172, Prestwick3_000172, Spectrum2_001819, Spectrum3_001711, Spectrum4_000179, Spectrum5_001332, ChemDiv2_005108, D0PB2W, AC1Q3ZH5, AC1Q3ZH6, AC1Q6LF3, Cambridge id 6649214, BSPBio_000063, BSPBio_003322, KBioGR_000697, KBioSS_000799, 5-26-14-00038 (Beilstein Handbook Reference), MLS000069731, BIDD:GT0586, DivK1c_000052, SCHEMBL149271, SPECTRUM2300357, SPBio_001837, SPBio_001984, BPBio1_000071, DTXSID5023031, BCBcMAP01_000126, CHEBI:94764, CTK8B1810, HMS500C14, KBio1_000052, KBio2_000799, KBio2_003367, KBio2_005935, KBio3_002542, KS-00000WEU, ZINC57358, 7-(beta-Hydroxyethyl)theophylline, MolPort-001-793-760, NINDS_000052, HMS1383I04, HMS1568D05, HMS2095D05, HMS2235K09, HMS3370P21, HMS3712D05, Etofylline 1.0 mg/ml in Methanol, HY-B1209, Tox21_110447, ANW-31370, BDBM50025585, CCG-39731, MFCD00055055, NSC113373, SBB057458, STK970528, AKOS000121416, Tox21_110447_1, CS-4837, GS-6113, MCULE-9071053702, NE11081, NSC-113373, IDI1_000052, IDI1_003823, SMP1_000162, 7-(beta-Hydroxyethyl)theophylline, solid, NCGC00016479-01, NCGC00016479-02, NCGC00016479-03, NCGC00016479-04, NCGC00016479-05, NCGC00016479-07, NCGC00016479-08, NCGC00016479-09, NCGC00016479-11, NCGC00022341-03, NCGC00022341-04, NCGC00178140-01, NCGC00178140-02, AJ-09675, ZB002088, LS-149582, AB00052458, FT-0668429, ST50409022, V0304, WLN: T56 BN DN FNVNVJ B2Q F1 H1, 1,3-Dimethyl-7-( beta-hydroxyethyl-xanthine, 1,3-Dimethyl-7-( beta-hydroxyethyl- xanthine, D07933, 110298-EP2292621A1, 110298-EP2298305A1, A828855, SR-01000000166, 7-(2-hydroxyethyl)-1,3-dimethyl-purine-2,6-dione, SR-01000000166-3, W-109548, BRD-K83064458-001-05-7, Z112207554, Etofylline, European Pharmacopoeia (EP) Reference Standard, 1H-Purine-2, 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-, 7-(2-Hydroxy-ethyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione, 3,7-dihydro-7-(2-hydroxyethyl)- 1,3-dimethyl-1H-purine-2,6-dione, 3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione (9CI), 7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione #, 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl- (9CI), Theophylline Related Compound F, United States Pharmacopeia (USP) Reference Standard


ID: 1532

chemical graph of compound 1532



InChIKey: NXFQHRVNIOXGAQ-YCRREMRBSA-N
SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6604200
synonyms found at PubChem are:
nitrofurantoin, 67-20-9, Macrodantin, 5-Nitrofurantoin, Furadantin, Furadonine, Nitrofurantoine, Furadantine, Furadantoin, Furadoine, Furadontin, Furantoin, Nifurantin, Nitrofuradantin, Nitrofurantoina, Berkfurin, Chemiofuran, Furachel, Furadonin, Furatoin, Furobactina, Macrobid, Novofuran, Orafuran, Parfuran, Trantoin, Urantoin, Urofurin, Welfurin, Zoofurin, Cyantin, Cystit, Furalan, Furina, Ituran, Nitoin, Urizept, Urodin, Urolong, Nitrofurantoinum, Furadantine mc, Uro-Tablinen, Fur-ren, Furadoninum, Macrofuran, Benkfuran, Dantafur, Furaloid, Nierofu, Macpac, Nitrex, Fua Med, N-Toin, Macrodantina, Berkfuran, Cistofuran, Gerofuran, Macrofurin, Nifuretten, Phenurin, Siraliden, Uerineks, Urofuran, Alfuran, Ceduran, Furabid, Furedan, PiyEloseptyl, Urolisa, Usaf ea-2, Furadantina MC, Furadantine-MC, Furophen T, Nitrofur-C, Ro-Antoin, Furadantin Retard, Uro-Selz, 1-(5-Nitro-2-furfurylideneamino)hydantoin, N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-Nitrofurfurylidene)amino)hydantoin, 1-[(5-Nitrofurfurylidene)amino]hydantoin, 1-(5-Nitro-2-furfurylidenamino)hydantoin, Nitrofurantoina [DCIT], NITROFURANTOIN, MACROCRYSTALLINE, N-(5-Nitro-2-furfurylidene)-1-aminohydantoin, Nitrofurantoine [INN-French], Nitrofurantoinum [INN-Latin], furophen, urodil, Furodantin, uro-tablineu, fua-med, NCI-C55196, NSC 2107, Furadantin (TN), NITROFURANTOIN MACROCRYSTALLINE, NSC 44150, N-(5-Nitro-2-furfurylideno)-1-aminohydantoina, NITROFURANTION, CCRIS 1192, UNII-927AH8112L, HSDB 3135, EINECS 200-646-5, Nitrofurantoin [USAN:INN:BAN:JAN], Fuamed, N-(5-Nitro-2-furfurylideno)-1-aminohydantoina [Polish], AI3-26388, MLS000028500, Nitrofurantoin (JAN/USP/INN), CHEBI:71415, Hydantoin, 1-((5-nitrofurfurylidene)amino)-, 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione, 1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, Ivadantin, C8H6N4O5, 927AH8112L, ND-3320, ND-7248, SMR000058271, 1-[(5-:nitrofurfurylidene)amino]hydantoin, 1-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione, N-(5-nitro-2-furfurylidene)-1-aminohyda ntoin, Furantoina, Furadoin, Furophen T-Caps, 2,4-Imidazolidinedione, 1-(((5-nitro-2-furanyl)methylene)amino)-, 1-(((5-nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione, 1-(((5-Nitrofuran-2-yl)methylene)-amino)imidazolidine-2,4-dione, 1-[(E)-(5-nitro-2-furyl)methyleneamino]imidazolidine-2,4-dione, 1-{[(1E)-(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione, 1-{[(E)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione, 2,4-Imidazolidenedione, 1-(((5-nitro-2-furanyl)methylene)amino)-, 1-(((5-Nitrofuran-2-yl)methylene)amino)imidazolidine-2,4-dione, 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene]amino]-, Hydantoin, 1-[(5-nitrofurfurylidene)amino]-, N-[5-Nitro-2-furfurylidene]-1-aminohydantoin, SR-05000001681, NSC2107, Furadoxyl, Uvamin, NSC-2107, NSC44150, Macrodantin (TN), NCGC00091505-01, NCGC00091505-07, Macrobid (TN), Urantoin (TN), Prestwick_358, Nitrofurantoin Macro, 5-Nitrofurantoindorn, J01XE01, Nitrofurantoin [USP:INN:BAN:JAN], Nitro Macro (TN), PubChem6954, Nitrofurantoin, 97%, Io>>uss>>a<<IxOo, Nitrofurantoin anhydrous, AC1O7GAU, Nitrofurantoinum anhydrous, Prestwick2_000168, Prestwick3_000168, Spectrum5_001367, Nitrofurantoin macrocrystal, Nitrofurantoin, crystalline, CHEMBL572, D0R0BX, ss>>a<<I(1)a currency, Nitrofurantoin Macrocrystals, cid_4509, Nitrofurantoin, macrocrystals, SCHEMBL29470, SCHEMBL29472, BSPBio_000035, BSPBio_002073, 1-{[(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione, ARONIS27199, BIDD:GT0181, SPECTRUM1500433, 1-[[(5-nitrofuran-2-yl)methylene]amino]imidazolidine-2,4-dione, BPBio1_000039, BDBM57045, CHEBI:95222, HMS500L06, 54-87-5 (hydrochloride salt), MolPort-001-018-217, MolPort-035-394-835, NXFQHRVNIOXGAQ-YCRREMRBSA-N, HMS1568B17, HMS1920P21, HMS2091H16, HMS2095B17, HMS3712B17, Pharmakon1600-01500433, 17140-81-7 (mono-hydrate), HY-A0090, ZINC7997568, CCG-40108, MFCD00003224, NSC757243, s4536, SBB056985, STK009471, STL454163, AKOS001678301, DB00698, LS-1560, NSC-757243, RTR-022602, IDI1_000224, NCGC00091505-03, NCGC00091505-04, NCGC00091505-05, NCGC00091505-06, NCGC00091505-08, NCGC00091505-09, NCGC00091505-10, AN-41883, CPD000058271, SAM002554913, SC-06194, 1-((5-nitrofurfurylidene)amino)-hydantoin, SBI-0051457.P003, KB-212253, TR-022602, AB00513815, N0883, ST24031483, C07268, D00439, J10193, Z-1941, AB00052052_03, A835659, Hydantoin, n-(5-nitro-2-furfurylidene)-1-amino-, Nitrofurantoin, VETRANAL(TM), analytical standard, I07-0015, Q-201479, SR-05000001681-1, SR-05000001681-2, SR-05000001681-3, SR-05000001681-4, BRD-K76927775-001-05-0, Nitrofurantoin, Antibiotic for Culture Media Use Only, Hydantoin, 1-[(5-nitrofurfurylidene)amino]- (7CI,8CI), 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione, (E)-1-[(5-nitro-2-furyl)methylideneamino]imidazolidine-2,4-dione, 1-([(5-Nitro-2-furyl)methylidene]amino)-2,4-imidazolidinedione #, 1-[(E)-(5-nitro-2-furanyl)methylideneamino]imidazolidine-2,4-dione, 1-{[(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione, Nitrofurantoin, United States Pharmacopeia (USP) Reference Standard, 1-[(1E)-2-(5-nitro(2-furyl))-1-azavinyl]-1,3-diazolidine-2,4-dione, N-(5-Io>>u-2-ss>>a<<NC(1/4)x>>u)-1- degrees +/->>u masculine poundOo, 1-{[(E)-1-(5-nitro-2-furyl)methylidene]amino}-1H-imidazole-2,4(3H,5H)-dione, 4-hydroxy-1-{[(E)-(5-nitrofuran-2-yl)methylidene]amino}-1,5-dihydro-2H-imidazol-2-one, N-(5-Nitro-2-furfurylidine)-1-aminohydantoin; N-(5-Nitrofurfurylidene)-1aminohydantoin, Nitrofurantoin, Pharmaceutical Secondary Standard; Certified Reference Material


ID: 1533

chemical graph of compound 1533



InChIKey: NXJCRELRQHZBQA-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C=CC(=O)OC2=C1)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2775
synonyms found at PubChem are:
5,7-Dimethoxycoumarin, citropten, 487-06-9, Limettin, Citroptene, Citraptene, Limetin, 5,7-Dimethoxy-2H-chromen-2-one, 5,7-dimethoxychromen-2-one, 5,7-Dimethoxy-2-benzopyrone, 2H-1-Benzopyran-2-one, 5,7-dimethoxy-, COUMARIN, 5,7-DIMETHOXY-, UNII-JWE1QQ247N, NSC 102793, 5,7-Dimethoxy-chromen-2-one, CCRIS 3595, 5,7-dimethoxy-coumarin, EINECS 207-646-4, BRN 0187066, JWE1QQ247N, AI3-36094, MLS002703744, NSC102793, Coumarin,7-dimethoxy-, 2H-1-Benzopyran-2-one,5,7-dimethoxy-, 5,7-Dimethoxy-2H-1-benzo-pyran-2-one, 5,7-Dimethyloxy-2H-1-benzopyran-2-one, 2H-1-Benzopyran-2-one,7-dimethoxy-, SMR000112321, 5,7-Dimethoxy-2H-1-benzopyran-2-one, Spectrum_000243, 5, 7-Dimethoxycoumarin, Coumarin derivative, 2a, AC1L1EFT, Spectrum2_000814, Spectrum3_001398, Spectrum4_000781, Spectrum5_001348, ACMC-1AM7E, DSSTox_CID_21421, DSSTox_RID_79725, DSSTox_GSID_41421, BSPBio_003016, KBioGR_001222, KBioSS_000723, 5-18-03-00199 (Beilstein Handbook Reference), MLS002207304, MLS002472928, Citropten, analytical standard, DivK1c_000391, SCHEMBL516577, SPECTRUM1500707, SPBio_000707, 5,7-Dimethoxycoumarin, 98%, CHEMBL481049, DTXSID1041421, BDBM93217, CTK4J0961, HMS501D13, KBio1_000391, KBio2_000723, KBio2_003291, KBio2_005859, KBio3_002236, NXJCRELRQHZBQA-UHFFFAOYSA-, ZINC57754, CHEBI:113528, MolPort-003-665-736, NINDS_000391, NXJCRELRQHZBQA-UHFFFAOYSA-N, HMS1921E18, HMS2268I06, 5,7-dimethoxy-1-benzopyran-2-one, Tox21_300942, 9155AF, CCG-40277, NSC217987, STL193281, AKOS015915990, MCULE-8767481325, NSC-102793, NSC-217987, SDCCGMLS-0066597.P001, IDI1_000391, NCGC00094841-01, NCGC00094841-02, NCGC00094841-03, NCGC00094841-04, NCGC00178344-01, NCGC00254844-01, AC-20780, AK167951, AN-45243, CAS-487-06-9, CC-20975, KB-73158, LS-55181, OR345352, ZB002255, DB-051575, TC-168439, FT-0619848, ST50319835, 487D069, A827593, AQ-358/43417403, C-10266, SR-05000002446, SR-05000002446-1, BRD-K78612426-001-02-6, BRD-K78612426-001-05-9, I14-52904, InChI=1/C11H10O4/c1-13-7-5-9(14-2)8-3-4-11(12)15-10(8)6-7/h3-6H,1-2H3


ID: 1534

chemical graph of compound 1534



InChIKey: NYIZXMGNIUSNKL-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=CC(=C1OC(=O)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 68093
synonyms found at PubChem are:
Dipyrocetyl, Movirene, Pyrocat, Tosiben, Dipyrocetylum, 2,3-Bis(acetyloxy)benzoic acid, 486-79-3, Dipyrocetyl [INN:DCF], 2,3-Diacetoxybenzoic acid, UNII-EF5UVE254C, Dipyrocetylum [INN-Latin], Dipirocetilo [INN-Spanish], Benzoic acid, 2,3-bis(acetyloxy)-, EINECS 207-641-7, 2,3-diacetyloxybenzoic acid, U.C.B. 5080, EF5UVE254C, 2,3-Dihydroxybenzoic acid diacetate, NCGC00095316-01, o-Pyrocatechuic acid, diacetate (6CI,8CI), Dipirocetilo, artromialgina, UCB 5080, Dipyrocetyl (INN), Spectrum_001753, SpecPlus_000837, Spectrum2_000417, Spectrum3_001754, Spectrum4_000218, Spectrum5_001049, AC1Q61GV, DIACETYLSALICYLIC ACID, DSSTox_CID_25976, DSSTox_RID_81267, DSSTox_GSID_45976, SCHEMBL26164, BSPBio_003488, KBioGR_000855, KBioSS_002233, DivK1c_006933, SPBio_000374, AC1L290M, ZINC1316, CHEMBL1451173, DTXSID9045976, KBio1_001877, KBio2_002233, KBio2_004801, KBio2_007369, KBio3_002708, CHEBI:107635, NYIZXMGNIUSNKL-UHFFFAOYSA-N, Pharmakon1600-01503032, HY-B1179, Tox21_111504, ACM486793, CCG-39955, NSC758212, AKOS022660241, CS-4788, NSC-758212, NCGC00095316-02, CAS-486-79-3, LS-36142, D07290, AB00052432_02, SR-01000872730, SR-01000872730-1, BRD-K47608922-001-02-1


ID: 1535

chemical graph of compound 1535



InChIKey: NYMXYZMHOZAPHQ-SEPHDYHBSA-N
SMILES: C(CN)C#N.C(CN)C#N.C(=C/C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5462653
synonyms found at PubChem are:
3-Aminopropanenitrile hemifumarate, 3-Aminopropionitrile, fumarate, beta-Aminopropionitrile, fumarate, Di-beta-aminopropionitrile fumarate, UNII-1O0893POYK, Propanenitrile, 3-amino-, (2E)-2-butenedioate (2:1), 1O0893POYK, EINECS 218-208-7, Bis(3-aminopropiononitrile) fumarate, NCGC00093569-01, Propionitrile, 3-amino-, fumarate (2:1), 3-Aminopropionitrile fumarate salt, Propionitrile, 3-amino-, fumarate, AC1NUWHZ, DSSTox_CID_25751, DSSTox_RID_81095, DSSTox_GSID_45751, 2-cyanoethylamine hemifumarate, CHEMBL1315165, DTXSID0045751, CHEBI:91084, MolPort-004-963-405, Bis(3-aminopropionitrile) fumarate, HMS3260K11, beta-aminopropionitrile hemifumarate, Tox21_111209, Tox21_500055, AKOS004910334, CCG-204150, LP00055, NCGC00260740-01, AK163705, CAS-2079-89-2, AX8084550, LS-124899, A0796, butenedioic acid; bis(|A aminopropionitrile), EU-0100055, 3-Aminopropionitrile fumarate salt, metabolite, A 3134, SR-01000076248, bis(2-cyanoethan-1-aminium) (2E)-but-2-enedioate, J-013637, SR-01000076248-1, 1202867-06-8, 1218900-68-5


ID: 1536

chemical graph of compound 1536



InChIKey: NZASCBIBXNPDMH-UHFFFAOYSA-N
SMILES: CCC1(C(=O)C=CNC1=O)CC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4994
synonyms found at PubChem are:
pyrithyldione, Pyrithyldion, Persedon, Presidon, Didropyridine, Dihydroprylone, Benedorm, Persidon, Prezidon, Pyridion, Pyridione, Tetridin, Tetridine, 77-04-3, 3,3-Diethyl-1H-pyridine-2,4-dione, Pyrithyldione [INN], NU 903, 3,3-Diethyl-2,4-pyridinedione, 3,3-Diethyl-2,4(1H,3H)-pyridinedione, Pyrithyldionum [INN-Latin], 2,4(1H,3H)-Pyridinedione, 3,3-diethyl-, NSC 89733, Pyrithyldiona [INN-Spanish], UNII-8AB20823CK, 3,3-Diethyl-2,4-dioxotetrahydropyridine, 3,3-Diethylpyridine-2,4(1H,3H)-dione, EINECS 201-000-5, BRN 0131564, 3,3-Diethyl-2,4[1H,3H]pyridinedione, MLS002154008, MLS002694954, NZASCBIBXNPDMH-UHFFFAOYSA-N, 8AB20823CK, Pyrithyldione (INN), CAS-77-04-3, NCGC00016315-02, DSSTox_CID_25262, DSSTox_RID_80777, DSSTox_GSID_45262, Pyrithyldiona, Pyrithyldionum, SMR001233336, 3,3-diethyl-1,3-dihydropyridine-2,4-dione, SR-01000633270, Prestwick_141, Spectrum_001352, 3,3-diethyl-2,4-(1h,3h)pyridinedione, AC1L1JDL, Prestwick0_000803, Prestwick1_000803, Prestwick2_000803, Prestwick3_000803, Spectrum2_001520, Spectrum3_001555, Spectrum4_000763, Spectrum5_001018, 3,4-dioxotetrahydropyridine, AC1Q2SP3, AC1Q2SP4, 3,4(1H,3H)-dione, BSPBio_000665, BSPBio_003030, KBioGR_001146, KBioSS_001832, 5-21-10-00086 (Beilstein Handbook Reference), 3,4(1H,3H)-pyridinedione, ARONIS24414, DivK1c_000161, DivK1c_000593, SCHEMBL893677, SPECTRUM1503085, SPBio_001599, SPBio_002586, BPBio1_000733, CHEMBL1722501, DTXSID4045262, CHEBI:94590, CTK6D0162, HMS500I03, HMS501N15, KBio1_000161, KBio1_000593, KBio2_001832, KBio2_004400, KBio2_006968, KBio3_002530, MolPort-001-783-607, NINDS_000161, NINDS_000593, HMS1570B07, HMS1922E03, HMS2097B07, HMS2230E07, HMS3369G22, HMS3714B07, Pharmakon1600-01503085, NSC89733, ZINC3861492, ZX-AS004779, Tox21_110368, BBL023649, CCG-39176, FCH917594, NSC-89733, NSC758237, SBB057262, STL356010, 2,3H)-Pyridinedione, 3,3-diethyl-, AKOS005267151, Tox21_110368_1, MCULE-7842760182, NSC-758237, IDI1_000161, IDI1_000593, 2,4-Dioxo-3,3-diethyltetrahydropyridine, NCGC00016315-01, NCGC00016315-03, NCGC00016315-06, NCGC00095001-01, NCGC00095001-02, SBI-0051768.P002, LS-131509, ST50308305, T8171, 3,3-DIETHYLTETRAHYDROPYRIDIN-2,4-DIONE, D07329, AB00052313_06, SR-01000633270-1, SR-01000633270-3, SR-01000633270-4, 3,3-diethyl-1,2,3,4-tetrahydro-2,4-pyridinedione, 3,3-diethyl-1,2,3,4-tetrahydropyridine-2,4-dione, BRD-K36116267-001-05-4, BRD-K36116267-001-08-8, Benedorm, Didropyridine, Dihydroprylone, Persedon, Presidon, Pyridion, Pyridione, Pyrithyldion, Pyrithyldione, Tetridin, Tetridine, InChI=1/C9H13NO2/c1-3-9(4-2)7(11)5-6-10-8(9)12/h5-6H,3-4H2,1-2H3,(H,10,12


ID: 1537

chemical graph of compound 1537



InChIKey: NZDMFGKECODQRY-UHFFFAOYSA-N
SMILES: CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 71478
synonyms found at PubChem are:
Maprotiline hydrochloride, 10347-81-6, Maprotiline Hcl, Ludiomil, Psymion, Deprilept, Maprotilline HCl, Ciba 34276 Ba, UNII-7C8J54PVFI, Maprotiline (hydrochloride), 9-(gamma-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene hydrochloride, EINECS 233-758-8, 7C8J54PVFI, BA 34276, MLS000069552, MLS000557000, N-Methyl-9,10-ethanoanthracene-9(10H)-propanamine hydrochloride, 9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-, hydrochloride, CPD000148117, SMR000058834, SMR000148117, Ludiomil (TN), N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine hydrochloride, 1-(3-Methylaminopropyl)dibenzo(b,e)bicyclo(2.2.2)octadiene hydrochloride, 9,10-Ethanoanthracene-9(10H)-propylamine, N-methyl-, hydrochloride, 1-(3-MethylaMinopropyl)dibenzo[b,e]bicyclo[2.2.2]octadienehydrochloride;1-(3-MethylaMinopropyl)dibenzo[b,e]bicyclo[2.2.2]octadienehydrochloride, 10262-69-8 (Parent), SR-01000076016, CAS-10347-81-6, MaprotilineHCl, Ludiomil HCl, 1-(3-methylaminopropyl)dibenzo[b,e]bicyclo[2.2.2]octadiene hydrochloride, Prestwick_749, Maprotiline hydrochloride [USP:JAN], Maprotiline hydrochloride [USAN:JAN], Opera_ID_513, Opera_ID_1466, Maprotiline(hydrochloride), Deprilept;Ludiomil;Psymion, AC1L2G8I, AC1Q38UP, C20H23N.HCl, DSSTox_CID_24507, DSSTox_RID_80277, DSSTox_GSID_44507, MLS000758284, MLS001148189, MLS001423998, SCHEMBL121014, SPECTRUM1500373, REGID_for_CID_71478, CHEBI:6691, CHEMBL1237135, DTXSID2044507, CTK8G0746, MolPort-000-826-653, MolPort-006-069-325, HMS1569E13, HMS1920J13, KUC112481C, Pharmakon1600-01500373, Maprotiline, Ludiomil Hydrochloride, BCP23366, HY-B0444, KS-00001F7N, Tox21_300992, Tox21_500812, CCG-38957, MFCD00079464, NSC757085, s2517, AKOS015961872, AKOS015994755, Maprotiline hydrochloride (JP17/USP), AC-8249, AN-8185, BCP9000894, CCG-220346, CS-2553, KS-5095, LP00812, NC00056, NSC-757085, NCGC00094145-01, NCGC00094145-02, NCGC00094145-03, NCGC00094145-04, NCGC00254894-01, NCGC00261497-01, KSC-315-031-, LS-66339, SAM001246989, SC-26760, BCP0726000234, AB0012620, AB2000619, EU-0100812, FT-0659758, M2527, D00818, M 9651, Maprotiline hydrochloride, >99% (HPLC), powder, 347M816, C-54992, SR-01000000134, J-000980, SR-01000000134-3, SR-01000076016-1, SR-01000076016-3, Maprotiline Hydrochloride 1.0 mg/ml in Methanol (as free base), 3-(9,10-ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine hydrochloride, Maprotiline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Maprotiline hydrochloride, United States Pharmacopeia (USP) Reference Standard, methyl(3-{tetracyclo[6.6.2.0(2),.0,(1)]hexadeca-2,4,6,9,11,13-hexaen-1-yl}propyl)amine hydrochloride, methyl(3-{tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaen-1-yl}propyl)amine hydrochloride, AC1LCW7I, SCHEMBL14973468, AKOS015896333, I06-2036


ID: 1538

chemical graph of compound 1538



InChIKey: NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES: CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 66062
synonyms found at PubChem are:
Thioridazine hydrochloride, 130-61-0, Thioridazine Hcl, Sonapax hydrochloride, Thioridazine chloride, Mellaril hydrochloride, Thioridazine.HCl, USAF SZ-B, Melleril (tablet), USAF SZ-3, Thioridazine (hydrochloride), Aldazine, EINECS 204-992-8, NSC 186060, MLS000028408, CHEBI:48566, Ridazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine hydrochloride, 10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride, 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride, SMR000058380, Mellaril (TN), 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylthiophenothiazine hydrochloride, 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine monohydrochloride, 10H-Phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-, monohydrochloride, Melzine, 10-[2-(1-Methyl-2-piperidyl)-ethyl]-2-[methylthiol]-phenothiazine, 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine hydrochloride, 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine hydrochloride, Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-, monohydrochloride, 1257-76-7, NSC186060, SR-01000000063, 10-[2-(1-Methyl-2-piperidyl)ethyl]-2-methylthiophenothiazine hydrochloride, Thioridazine hydrochloride [JAN], 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride, 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine;hydrochloride, Thioridazine hydrochloride intensol, Prestwick_437, Thioridazine hydrochloride [USP:JAN], Opera_ID_1713, CAS-130-61-0, AC1L24JE, AC1Q3C6I, DSSTox_CID_29360, DSSTox_RID_83476, DSSTox_GSID_49401, SCHEMBL41430, labotest-bb lt00451961, C21H27ClN2S2, MLS001148599, MLS002222212, C21H26N2S2.HCl, SPECTRUM1500575, CHEMBL1200916, DTXSID9049401, CTK8G3443, AOB5375, MolPort-001-727-928, HMS1568O17, HMS1921E11, Pharmakon1600-01500575, BCP19941, HY-B0965, Thioridazine hydrochloride, >=99%, Tox21_202801, Tox21_501252, CCG-39270, MFCD00012655, NSC757349, SBB057665, AKOS015994763, API0024685, CS-4450, KS-5108, LP01252, MCULE-1090059754, NC00594, NSC-186060, NSC-757349, OR20007, Thioridazine hydrochloride (JP17/USP), NCGC00094492-01, NCGC00094492-02, NCGC00094492-03, NCGC00094492-04, NCGC00094492-05, NCGC00260347-01, NCGC00261937-01, AN-23047, CPD000058380, I584, SAM002564240, AB0013772, LS-105607, EU-0101252, FT-0631759, ST50412003, KS-00001859, D00798, T 9025, 22857-EP2295421A1, 22857-EP2315502A1, 22857-EP2371810A1, 22857-EP2371812A1, A806110, SR-01000000063-2, SR-01000000063-7, W-108347, WLN: T C666 BN ISJ ES1 B2-BT6NTJ A1 & GH, Z2784093622, Thioridazine Hydrochloride 1.0 mg/ml in Methanol (as free base), 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazinmono, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride, 10-[2-(1-methyl(2-piperidyl))ethyl]-2-methylthiophenothiazine, chloride, Thioridazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)phenothiazine hydrochloride, 10-[2-(1-methyl-2-piperidyl)-ethyl]-2-[methylthiol]-phenothiazine hydrochloride, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine hydrochloride, 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanyl-phenothiazine hydrochloride, 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine hydrochloride, 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid, Thioridazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 107388-89-6, AC1LCW70, AKOS015904302, I14-16541, 10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine HCl, hydron; 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine; chloride


ID: 1539

chemical graph of compound 1539



InChIKey: NZHGWWWHIYHZNX-CSKARUKUSA-N
SMILES: COC1=C(C=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5282230
synonyms found at PubChem are:
tranilast, 53902-12-8, Rizaben, trans-Tranilast, Tranilastum, 70806-55-2, MK 341, N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Tranilastum [INN-Latin], Tranilast [USAN:INN:JAN], Tranpro, UNII-HVF50SMY6E, Tranilast trans-, SB-252218, MK-341, Rizaben (TN), Tranilast (SB 252218), Tranilast (trans-), 3,4-DAA, n-(3',4'-dimethoxycinnamoyl) anthranilic acid, HVF50SMY6E, MLS000028468, C18H17NO5, CHEBI:77572, Anthranilic acid, N-(3,4-dimethoxycinnamoyl)-, NZHGWWWHIYHZNX-CSKARUKUSA-N, 2-((3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl)amino)benzoic acid, MFCD00864787, Tranilast sodium, (E)-2-(3-(3,4-dimethoxyphenyl)acrylamido)benzoic acid, NU-3450, NCGC00018185-05, SMR000058373, 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid, 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic Acid, T 0318, 53902-17-3, N-(3&prime;,4&prime;-Dimethoxycinnamoyl)anthranilic Acid, 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid, 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino] benzoic acid, 2-{[(2e)-3-(3,4-Dimethoxyphenyl)prop-2-Enoyl]amino}benzoic Acid, tranilast hydrate, 2-({(2E)-3-[3,4-bis(methyloxy)phenyl]prop-2-enoyl}amino)benzoic acid, SR-01000003092, BENZOIC ACID, 2-((3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL)AMINO)-, Molecule 20, N-(3&prime, AC1NQZP4, Opera_ID_1657, DSSTox_CID_3693, D00PVQ, D0E6OC, 2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid, DSSTox_RID_77152, DSSTox_GSID_23693, Lopac0_001193, SCHEMBL29875, BSPBio_003561, ZINC797, MLS000759509, MLS001065902, MLS001077269, MLS001424045, MLS002207030, MLS006010043, Tranilast (JAN/USAN/INN), SPECTRUM1505333, CHEMBL415324, GTPL6326, Tranilast (JP17/USAN/INN), 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic Acid, DTXSID7023693, BDBM21613, CHEBI:92320, AOB5086, MolPort-000-375-102, HMS2051F05, HMS2089L07, HMS2094I21, HMS2230F18, HMS3263P07, HMS3648A16, HMS3713J04, Pharmakon1600-01505333, BCP06359, BCP15888, HY-B0195, Tox21_110836, Tox21_501193, AC-940, CCG-39992, HSCI1_000076, NSC758970, SBB052710, AKOS002841076, Tranilast, >=98% (HPLC), powder, AN-6736, CS-2092, DB07615, KS-1193, LP01193, NC00171, NSC-758970, NCGC00018185-04, NCGC00018185-06, NCGC00018185-08, NCGC00018185-09, NCGC00018185-10, NCGC00018185-20, NCGC00021458-04, NCGC00021458-05, NCGC00021458-07, NCGC00261878-01, Rizaben;MK 341;Tranpro;SB 252218, BC204132, CPD000058373, I586, LS-37150, N 5', SAM001246737, SB252218, SC-12181, SBI-0051160.P003, AB0013774, AB2000109, CAS-53902-12-8, KB-226710, SB 252218, EU-0101193, KB-3357058, S1439, N-(3 ,4 -dimethoxycinnamoyl)anthranilic acid, D02027, AB00382987-18, AB00382987-19, AB00382987_21, 53902-12-8,104931-56-8(sodiumsalt), 902T173, Q-201849, SR-01000003092-2, SR-01000003092-4, SR-01000003092-9, BRD-K17849083-001-02-2, BRD-K17849083-001-03-0, BRD-K19533706-001-01-9, Rizaben, SB 252218, MK 341, Tranpro ,Tranilast, SR-01000003092-16, 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid, (E)-2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid, 2-?[[3-?(3-?methoxy-?4-?propoxyphenyl)?-?1-?oxo-?2-?propen-?1-?yl]?amino]?-Benzoic acid, D27


ID: 1540

chemical graph of compound 1540



InChIKey: NZVQLVGOZRELTG-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(O1)C=C3C(=C2OC)C=CO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6716
synonyms found at PubChem are:
Visnagin, Desmethoxykhellin, 82-57-5, Visnagidin, Visnagine, 5-Methoxy-2-methylfuranochromone, 4-Methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one, UNII-P64438MLBW, C13H10O4, EINECS 201-430-3, 4-Methoxy-7-methyl-furo[3,2-g]chromen-5-one, NSC 100593, BRN 0234955, CHEMBL45176, P64438MLBW, CHEBI:10002, NZVQLVGOZRELTG-UHFFFAOYSA-N, 4-Methoxy-7-methyl-5H-furo(3,2-g)(1)-benzopyran-5-one, 5H-Furo[3,2-g][1]benzopyran-5-one, 4-methoxy-7-methyl-, 5H-FURO(3,2-g)(1)BENZOPYRAN-5-ONE, 4-METHOXY-7-METHYL-, 4-Methoxy-7-methylfuro(3,2-g)chromen-5-one, 4-methoxy-7-methylfuro[3,2-g]chromen-5-one, 5H-Furo[3,2-g][1]benzopyran-5-one,4-methoxy-7-methyl-, 5-methoxy-2-methylfurano[3,2-g]chromen-4-one, SR-01000765669, Spectrum_001227, SpecPlus_000453, Spectrum2_001796, Spectrum3_001340, Spectrum4_001766, Spectrum5_000351, D0MH4R, Oprea1_854963, BSPBio_003099, GTPL433, KBioGR_002251, KBioSS_001707, SPECTRUM310041, 5-19-06-00030 (Beilstein Handbook Reference), MLS000697721, DivK1c_006549, SCHEMBL498450, SPBio_001751, AC1L1N57, MEGxp0_000332, CTK5E9834, KBio1_001493, KBio2_001707, KBio2_004275, KBio2_006843, KBio3_002319, NZVQLVGOZRELTG-UHFFFAOYSA-, DTXSID50231509, FUK-724, MolPort-001-740-507, 5-Methoxy-2-methyl-furanochromone, HMS2268P15, ZINC120179, 5H-Furo[3, 4-methoxy-7-methyl-, BBL027492, BDBM50051349, CCG-38444, LMPK13110003, NSC100593, SBB057568, STL372894, AKOS015955735, MCULE-6909437128, NSC-100593, SDCCGMLS-0066603.P001, NCGC00095626-01, NCGC00095626-02, NCGC00178297-01, 4CN-1210, CC-35616, LS-70733, SMR000112234, ZB004072, TR-025804, FT-0603293, ST50307139, W2039, C09049, C-13326, L000822, 4-methoxy-7-methylpyrano[3,2-f][1]benzoxol-5-one, SR-01000765669-3, SR-01000765669-4, 4-Methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one #, BRD-K68995359-001-02-8, BRD-K68995359-001-06-9, I14-100522, 4-Methoxy-7-methyl-5H-furo[3,2-g]-1-benzopyran-5-one, 4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one, 97%, InChI=1/C13H10O4/c1-7-5-9(14)12-11(17-7)6-10-8(3-4-16-10)13(12)15-2/h3-6H,1-2H3


ID: 1541

chemical graph of compound 1541



InChIKey: NZZIMKJIVMHWJC-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)CC(=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 8433
synonyms found at PubChem are:
Dibenzoylmethane, 120-46-7, 1,3-Diphenylpropane-1,3-dione, 1,3-DIPHENYL-1,3-PROPANEDIONE, 1,3-Propanedione, 1,3-diphenyl-, 2-Benzoylacetophenone, Phenyl phenacyl ketone, Rhodiastab 83, omega-Benzoylacetophenone, Dibenzoyl-methane, Karenzu DK2, UNII-ANS7ME8OKC, NSC 6266, ANS7ME8OKC, EINECS 204-398-9, .omega.-Benzoylacetophenone, BRN 0514910, AI3-19022, CHEBI:75417, NZZIMKJIVMHWJC-UHFFFAOYSA-N, 1,3-Diphenyl-propane-1,3-dione, dibenzoyl methane, phenacyl phenyl ketone, Dibenzoylmethan, CCRIS 8445, Karenzu DK 2, 1, 1,3-diphenyl-, AC1L1QZP, AC1Q5GTX, Spectrum2_000038, Spectrum3_001950, ACMC-209a7j, D02BDL, EC 204-398-9, AC1Q1HE2, DSSTox_CID_21247, DSSTox_RID_79661, DSSTox_GSID_41247, SCHEMBL39582, BSPBio_003550, KSC174Q7F, MLS002695996, SPECTRUM1505311, SPBio_000135, CHEMBL371523, 1,3-diphenyl-1,3-propandione, 1,3-diphenyl-1,3-propanedion, DTXSID3041247, BDBM22727, CTK0H4872, KBio3_002841, NSC6266, 1,3-Diphenyl-Propan-1,3-Dion, MolPort-001-759-976, HMS3091A20, KS-00000C2Z, NSC-6266, STR01439, ZINC4530702, 1,3-Diphenylpropanedione (Related), Tox21_300686, ANW-17501, CCG-40047, MFCD00003085, STK372683, AKOS000119639, CS-W010447, MCULE-6320643310, NE10265, RP27517, RTR-003386, TRA0010805, 1,3-Diphenyl-1,3-propanedione, 98%, UPCMLD0ENAT5883819:001, NCGC00095298-01, NCGC00095298-02, NCGC00095298-03, NCGC00095298-04, NCGC00254594-01, AC-11379, AJ-51565, AN-22822, CAS-120-46-7, CJ-12137, KB-76490, M261, SC-19029, SMR001253722, DB-041558, LS-120771, TR-003386, AM20020283, D0910, FT-0624640, ST24026765, ST50319429, I14-6007, W-108476, BRD-K01555864-001-02-8, Dibenzoylmethane (chronic inflammatory disease/cancer), F0001-0329, Z256709078


ID: 1542

chemical graph of compound 1542



InChIKey: OAPVUSSHCBRCOL-KBHRXELFSA-N
SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 54686764
synonyms found at PubChem are:
DEMECLOCYCLINE HYDROCHLORIDE, 64-73-3, Demeclocycline HCL, Detravis, Clortetrin, Declomycin, Ledermicina, Ledermycine, Veraciclina, Demeplus, Detracin, 7-Chloro-6-demethyltetracycline hydrochloride, Declomycin hydrochloride, Elkamicina, Ledermycin, Demethylchlortetracycline hydrochloride, 6-Demethyl-7-chlorotetracycline hydrochloride, UNII-29O079NTYT, demeclocycline, Demethylchlorotetracycline hydrochloride, Ledermycin hydrochloride, Demeclocycline (hydrochloride), EINECS 200-592-2, Demeclocycline hydrochloride (internal use), MLS000028422, 29O079NTYT, CHEBI:59725, SMR000058439, DSSTox_CID_25252, DSSTox_RID_80775, DSSTox_GSID_45252, 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride, 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-, 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-, Declomycin (TN), SR-01000075825, Demetraciclina, Meciclin, (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride, Prestwick_235, Demeclocycline hydrochloride [USP:BAN], AC1NQXVY, Demeclocycline hydrochloride [USAN:BAN], Opera_ID_242, AC1O7EUI, CAS-64-73-3, NCGC00016290-01, EC 200-592-2, C21H21ClN2O8.HCl, Demethylchlortetracycline HCl, SCHEMBL41286, MLS001076091, MLS001333687, Demethylchlortetracycline HCl;, SPECTRUM1500226, 127-33-3 (Parent), CHEMBL1200474, DTXSID0045252, MolPort-003-666-156, HMS1570G08, HMS1920C20, Pharmakon1600-01500226, Demeclocycline hydrochloride (USP), EBD31499, REGID_for_CID_54686764, Tox21_110354, Tox21_500421, MFCD00082371, NSC756708, s4279, AKOS015965080, Tox21_110354_1, CCG-212562, CS-3073, LP00421, NSC-756708, KS-00000Q36, NCGC00162149-07, NCGC00261106-01, AK110703, BC219571, CC-26332, HY-17560, LS-93856, EU-0100421, FT-0603113, ST24046427, Demethylchlortetracycline hydrochloride (JP17), D 6140, D00290, 064D733, C-22948, SR-01000075825-1, SR-01000075825-5, W-109265, Demeclocycline hydrochloride, >=90% (HPLC), powder, Demeclocycline hydrochloride, Antibiotic for Culture Media Use Only, Demeclocycline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Demeclocycline for system suitability, EuropePharmacopoeia (EP) Reference Standard, Demeclocycline HCl, Pharmaceutical Secondary Standard; Certified Reference Material, Demeclocycline hydrochloride, United States Pharmacopeia (USP) Reference Standard, (2E,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride, (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride, [4S-(4|A,4a|A,5a|A,6|A,12a|A)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride, [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide hydrochloride, 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-, monohydrochloride, SCHEMBL1649184


ID: 1543

chemical graph of compound 1543



InChIKey: OAQFLNPTAZZENS-UHFFFAOYSA-N
SMILES: COC1=C(C2=C(C=C1)C(=O)C3=CC(=C(C=C3CC(=O)CO2)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4309557
synonyms found at PubChem are:
HAEMATOXYLONE, TETRAMETHYL-, SPBio_000117, Spectrum_000683, SpecPlus_000105, Spectrum2_000189, Spectrum3_000202, Spectrum4_001518, Spectrum5_000315, AC1N7X0N, BSPBio_001783, KBioGR_002215, KBioSS_001163, DivK1c_006201, CHEMBL3039170, CHEBI:93413, KBio1_001145, KBio2_001163, KBio2_003731, KBio2_006299, KBio3_001283, CCG-40003, BRD-K80307267-001-01-3


ID: 1544

chemical graph of compound 1544



InChIKey: OBKXEAXTFZPCHS-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to an interaction partner of CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4775
synonyms found at PubChem are:
4-PHENYLBUTYRIC ACID, 4-Phenylbutanoic acid, 1821-12-1, Benzenebutanoic acid, Benzenebutyric acid, Phenylbutyrate, gamma-Phenylbutyric acid, omega-Phenylbutanoic acid, Phenylbutyric acid, 4-phenylbutyrate, Butyric acid, 4-phenyl-, 4-Phenyl-n-butyric acid, 1-Phenylbutyric acid, 4-PHENYL-BUTANOIC ACID, 4-phenylbutans, 4-Phenyl-butyric acid, omega-phenylbutyric acid, GAMMA-PHENYL-BUTYRIC ACID, UNII-7WY7YBI87E, gamma-Phenyl-n-butyric acid, CHEBI:41500, 4-Phenyl butyric acid, NSC 295, gamma-Phenylbutanoic acid, EINECS 217-341-8, HDInhib_000004, .gamma.-Phenylbutyric acid, .omega.-Phenylbutanoic acid, 7WY7YBI87E, AI3-12065, MLS000069408, OBKXEAXTFZPCHS-UHFFFAOYSA-N, 2-methyl-1-phenyl-propan-2-amine, FR-2080, SMR000059104, NCGC00018113-03, Benzenebutyrate, Pheburane, Benzenebutanoate, g-Phenylbutyrate, g-Phenylbutanoate, w-Phenylbutanoate, g-phenyl-Butyrate, 4-phenyl-Butyrate, gamma-Phenylbutyrate, 4-PhenylbutyricAcid, 4-Phenybutytic acid, g-Phenylbutyric acid, gamma-Phenylbutanoate, omega-Phenylbutanoate, 4-Phenyl-n-butyrate, g-Phenylbutanoic acid, gamma-phenyl-Butyrate, w-Phenylbutanoic acid, g-phenyl-Butyric acid, Spectrum_001331, 2ay7, 3tz2, ACMC-209eip, Opera_ID_387, SpecPlus_000814, AC1L1IXE, Spectrum2_001798, Spectrum3_000782, Spectrum4_000092, Spectrum5_001003, PHENYLBUTANOIC ACID, bmse000701, D0B7CH, Epitope ID:167707, EC 217-341-8, AC1Q5W0X, AC1Q75DT, AC1Q75DU, SCHEMBL1716, CHEMBL1469, 3-phenylpropylcarboxylic acid, 4-Phenolsulfonic acid sodium, 4-Phenylbutyric acid, 99%, BSPBio_002484, KBioGR_000384, KBioSS_001811, KSC174M0L, MLS001076482, DivK1c_006910, SPBio_001755, .gamma.-Phenyl-n-butyric acid, GTPL8480, NSC295, DTXSID2037631, 1716-12-7 (hydrochloride), Butyric acid, 4-phenyl-(8CI), CTK0H4605, KBio1_001854, KBio2_001811, KBio2_004379, KBio2_006947, KBio3_001704, KS-00000CFT, OBKXEAXTFZPCHS-UHFFFAOYSA-, ZINC56568, NSC-295, MolPort-000-871-587, HMS2234G14, HMS3259M07, BCP10715, CS-D1686, HY-A0281, STR05306, 4-Phenylbutyric acid, 99% 25g, ANW-23087, CCG-39733, CX1106, HTS001426, MFCD00004403, SBB008452, STL164372, AKOS000154540, AC-3254, AM84635, DB06819, LS10686, MCULE-6322732346, NC00469, PS-4322, RP22720, RTC-069503, TRA0064777, NCGC00018113-01, NCGC00018113-02, NCGC00018113-04, AJ-09313, AN-13143, BC678065, CPD000059104, H331, KB-72857, NCI60_002455, NCI60_020145, SAM002264634, SC-22740, SY004771, AB1001924, LS-173716, TC-069503, TL8001458, FT-0082934, FT-0619401, P0643, ST24029204, ST50209061, EN300-35719, C21793, Z-3857, I01-3326, Q-200507, BRD-K67102207-001-02-6, BRD-K67102207-236-01-0, F2190-0002, InChI=1/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)


ID: 1545

chemical graph of compound 1545



InChIKey: OBMLHUPNRURLOK-XGRAFVIBSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC[C@@H]4[C@@]3(C[C@@H]5[C@H](C4)S5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 443935
synonyms found at PubChem are:
epitiostanol, Thiodrol, epithiostanol, 2363-58-8, UNII-YE7586973L, NSC 194684, YE7586973L, Epitiostanol [INN:JAN], Epitiostanolum [INN-Latin], Epitiostano, 2,3-Epithioandrostan-17-ol, C19H30OS, 10275S, Epitiostanolum, 10275-S, 2alpha,3alpha-Epithio-5alpha-androstan-17beta-o1, 2-alpha,3-alpha-Epithio-5-alpha-androstan-17-beta-ol, NCGC00016609-01, CAS-2363-58-8, 2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol, AC1L9FFI, Epitiostanol (JAN/INN), Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)-, SCHEMBL8995, DSSTox_CID_25367, DSSTox_RID_80830, DSSTox_GSID_45367, CHEMBL2106161, DTXSID2045367, CHEBI:31546, ZINC4215820, Tox21_110520, AKOS030573839, API0011345, CCG-221006, I142, 2|A,3|A-Epithio-5|A-androstan-17|A-ol, C12694, D01265, 2alpha,3alpha-epithio-5alpha-androstane-17beta-ol, (2|A,3|A,5|A,17|A)-2,3-Epithioandrostan-17-ol, 5alpha-Androstan-17beta-ol, 2alpha,3alpha-epithio- (8CI), Androstan-17-ol, 2,3-epithio-, (2alpha,3alpha,5alpha,17beta)- (9CI)


ID: 1546

chemical graph of compound 1546



InChIKey: OBZFLUDUSNCZKL-UHFFFAOYSA-N
SMILES: C1C(C=CC=C1C(=O)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 198382
synonyms found at PubChem are:
Gabaculine hydrochloride, 59556-17-1, 3-Amino-2,3-dihydrobenzoic acid hydrochloride, Gabaculine HCl, d,l-Gabaculine hydrochloride, EINECS 261-802-6, D,L-Gabaculine, Hydrochloride, (+-)-5-Amino-1,3-cyclohexadiene-1-carboxylic acid hydrochloride, 1,3-Cyclohexadiene-1-carboxylic acid, 5-amino-, hydrochloride, (+-)-, (1)-5-Aminocyclohexa-1,3-diene-1-carboxylic acid hydrochloride, 1,3-Cyclohexadiene-1-carboxylicacid, 5-amino-, hydrochloride (1:1), MLS000859989, SCHEMBL667842, (+-)-Gabaculine hydrochloride, AC1L558Q, CHEMBL1256019, CTK1H1887, Tox21_500006, MFCD00036983, AKOS027380321, gabaculine hydrochloride, (+-)-isomer, CCG-221310, LP00006, NCGC00093532-01, NCGC00260691-01, LS-56252, SMR000326848, EU-0100006, FT-0668919, n degrees I inverted question markaAO NIEaNI, A 3539, (+/-)-3-AMINO-2,3-DIHYDROBENZOIC ACID, SR-01000075664, SR-01000075664-1, 3-Amino-2,3-dihydrobenzoic acid hydrochloride, >=98%, 5-Amino-1,3-cyclohexadiene-1-carboxylic acid hydrochloride, 5-aminocyclohexa-1,3-diene-1-carboxylic acid hydrochloride, 5- degrees +/->>u-1,3->>.(1/4) masculine paragraph signthornI(c)-1-oEEa NIEaNI


ID: 1547

chemical graph of compound 1547



InChIKey: OCAPBUJLXMYKEJ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2378
synonyms found at PubChem are:
bifonazole, 60628-96-8, Mycospor, Trifonazole, Bifonazol, Bifonazolum, Amycor, BAY H 4502, Azolmen, Bifonazol [INN-Spanish], Bifonazolum [INN-Latin], 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole, 1-(alpha-(4-Biphenylyl)benzyl)imidazole, 1-[phenyl-(4-phenylphenyl)methyl]imidazole, (+-)-1-(p,alpha-Diphenylbenzyl)imidazole, Mycosporan, 1-(p,alpha-Diphenylbenzyl)imidazole, Bay-h-4502, 1-[4,alpha-Diphenylbenzyl]-imidazole, 1H-Imidazole, 1-([1,1'-biphenyl]-4-ylphenylmethyl)-, Mycospor (TN), Bay H-4502, (+/-)-Bifonazole, Bifonazole [USAN:BAN:INN:JAN], EINECS 262-336-6, BRN 0618427, 1-([1,1'-Biphenyl]-4-yl(phenyl)methyl)-1H-imidazole, MLS000028576, CHEMBL277535, CHEBI:78692, 1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole, OCAPBUJLXMYKEJ-UHFFFAOYSA-N, C22H18N2, 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-, (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole, NCGC00018254-03, CPD000058970, SMR000058970, 1-(ALPHA,4-DIPHENYLBENZYL)IMIDAZOLE, Imidazole, 1-(alpha-(4-biphenylyl)benzyl)-, 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole, 1-[phenyl(4-phenylphenyl)methyl]-1H-imidazole, DSSTox_CID_25631, DSSTox_RID_81013, DSSTox_GSID_45631, 1-(BIPHENYL-4-YL(PHENYL)METHYL)-1H-IMIDAZOLE, Bifokey, Bifomyk, Moldina, Bifon, 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-, (+-)-, CAS-60628-96-8, SR-01000003136, bifazol, Bedriol, Bifonazole,(S), Bifonazole [USAN:INN:BAN:JAN], Canespor (TN), Canesten Extra Bifonazol, AC1L1DJN, 1-(PHENYL-(4-PHENYLPHENYL)-METHYL)IMIDAZOLE, Bayer brand of bifonazole, Opera_ID_1656, Spectrum2_000035, Spectrum3_001970, (.+/-.)-Bifonazole, Bifonazole, 99% 1g, D0AA2D, Bioglan brand of bifonazole, Inkeysa brand of bifonazole, cid_2378, Canesten brand of bifonazole, Juventus brand of bifonazole, SCHEMBL36803, BSPBio_003570, 5-23-04-00292 (Beilstein Handbook Reference), MLS000759537, MLS001074074, MLS001424050, Dermapharm brand of bifonazole, SPECTRUM1505309, SPBio_000129, IMI028, Bifonazole (JP15/USAN/INN), Bifonazole (JP17/USAN/INN), Bifonazole, >=98% (HPLC), DTXSID9045631, CTK8F8126, KBio3_002922, KS-00000XNE, MolPort-003-666-632, HMS1922B18, HMS2051F04, HMS2090K13, HMS2093B09, HMS2232J24, HMS3374H02, HMS3393F04, HMS3651G21, HMS3715L21, Pharmakon1600-01505309, BCP22297, HY-B0301, Tox21_110850, BDBM50128548, CCG-39996, DL-338, KM0422, MFCD00865567, NSC758954, s1854, STK618771, Merck Lipha Sante brand of bifonazole, AKOS005553008, Tox21_110850_1, AB07497, BCP9000410, CCG-100993, CS-2335, DB04794, KS-5111, MCULE-1275076931, NC00243, NSC-758954, [phenyl(4-phenylphenyl)methyl]imidazole, MRF-0000274, NCGC00018254-02, NCGC00018254-04, NCGC00018254-05, NCGC00018254-08, NCGC00089815-02, NCGC00089815-03, NCGC00089815-04, 1-[biphenyl-4-yl(phenyl)methyl]imidazole, AC-15414, AN-39438, BC209083, LS-78073, SAM001246775, SC-77631, SBI-0206755.P001, 1-(.alpha.-(4-Biphenylyl)benzyl)imidazole, 1-[alpha-(4-biphenylyl)-benzyl]-imidazole, AB0011811, AB2000334, ST2403297, TL8003842, (Biphenyl-4-yl)-imidazol-1-yl-phenylmethane, B4173, FT-0652733, ST50993921, VU0239694-7, 28B968, D01775, Imidazole, 1-(.alpha.-(4-biphenylyl)benzyl)-, AB00383029-16, AB00383029_17, AB00383029_18, (.+/-.)-1-(p,.alpha.-Diphenylbenzyl)imidazole, A832816, 1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole, I01-2098, Q-200717, SR-01000003136-4, SR-01000003136-6, BRD-A94543220-001-02-3, BRD-A94543220-001-12-2, (+-)-1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole, 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole), 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole), 1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole), 1-[[1,1'-Biphenyl]-4-yl(phenyl)methyl]-1H-imidazole #, Bifonazole, European Pharmacopoeia (EP) Reference Standard, 1H-Imidazole, 1-([1,1'-biphenyl]-4-ylphenylmethyl)-, (.+/-.)-, Bifonazole, Pharmaceutical Secondary Standard; Certified Reference Material, Bifonazole for system suitability, European Pharmacopoeia (EP) Reference Standard


ID: 1548

chemical graph of compound 1548



InChIKey: OCDGBSUVYYVKQZ-UHFFFAOYSA-N
SMILES: CN(C)CC1=CNC2=CC=CC=C21

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6890
synonyms found at PubChem are:
Gramine, 87-52-5, 3-(Dimethylaminomethyl)indole, Donaxine, Donaxin, Gramin, 1H-Indole-3-methanamine, N,N-dimethyl-, beta-Dimethylaminomethylindole, 1-(1H-indol-3-yl)-N,N-dimethylmethanamine, Indol-3-ylmethyldimethylamine, (1H-indol-3-ylmethyl)dimethylamine, NSC 16892, (1H-Indol-3-ylmethyl)-dimethyl-amine, (Indol-3-ylmethyl)dimethylamine, 3-[(Dimethylamino)methyl]indole, Donaxine;Gramine, UNII-FGQ8A78L14, Indolalkylamine der., 3-(N,N-Dimethylaminomethyl)indole, EINECS 201-749-8, Indole, 3-[(dimethylamino)methyl]-, N,N-Dimethyl-1H-indole-3-methanamine, AI3-52146, FGQ8A78L14, .beta.-Dimethylaminomethylindole, 1-(1H-indol-3-yl)-N,N-dimethyl-methanamine, OCDGBSUVYYVKQZ-UHFFFAOYSA-N, N,N-Dimethyl-1H-indole-3-methylamine, INDOLE, 3-((DIMETHYLAMINO)METHYL)-, 3-((N,N-Dimethylamino)methyl)indole (Gramine), 3-[Dimethylaminomethyl]indole, 3-((Dimethylamino)methyl)-Indole, 3-[(Dimethylamino)methyl]-Indole, Prestwick_245, PubChem8121, Gramine, 99%, Enamine_005691, AC1L1NIY, Prestwick0_000629, Prestwick1_000629, Prestwick2_000629, Prestwick3_000629, Oprea1_150946, SCHEMBL63578, b-(Dimethylaminomethyl)indole, BSPBio_000598, MLS002153919, beta -dimethylaminomethylindole, SCHEMBL445889, SPBio_002817, BPBio1_000658, CHEMBL254348, beta-(Dimethylaminomethyl)indole, DTXSID3058955, CHEBI:28948, CTK8B5338, KS-00000DHR, ZINC73686, MolPort-001-759-339, HMS1410C15, HMS1569N20, HMS2096N20, HMS2268O03, HMS3651E18, 3-Dimethylaminomethylindol (gramin), ACT05054, NSC16892, TNP00029, WLN: T56 BMJ D1N1&1, ANW-48354, CCG-46378, MFCD00005629, NSC-16892, s2304, SBB003799, STL146344, (1H-Indol-3-ylmethyl)-dimethylamine, AKOS001055234, MCULE-3643815953, RTR-027517, 1H-Indol-3-yl-N,N-dimethylmethanamine, CAS-87-52-5, IDI1_007926, NCGC00016343-01, NCGC00016343-02, NCGC00016343-03, NCGC00016343-04, NCGC00016343-05, NCGC00142364-01, NCGC00142364-02, NCGC00142364-03, (1H-indol-3-yl)-N,N-dimethylmethanamine, AC-15584, AJ-10294, AN-42384, AS-11847, BC209294, BR-30161, KB-87702, LS-82953, SC-07104, SMR000112262, ST023280, 1H-Indol-3-yl-N,N-dimethylmethanamine #, AB0007640, AB1000351, TR-027517, 4CH-009343, D0653, FT-0603302, N,N-Dimethyl-1H-indole-3-methanamine, 9CI, N-(1H-indol-3-ylmethyl)-N,N-dimethylamine, N2337, ST24028337, C08304, S-5694, SR-01000636080, SR-01000636080-1, SR-01000636080-4, BRD-K26005076-001-03-7, BRD-K26005076-001-06-0, InChI=1/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H


ID: 1549

chemical graph of compound 1549



InChIKey: OCHPVPSALUKLOM-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C3(C(CO2)OC4=C(C3=O)C=CC(=C4C(=O)O)O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4646739
synonyms found at PubChem are:
12a-HYDROXY-9-DEMETHYLMUNDUSERONE-8-CARBOXYLIC ACID, KBio2_003841, Spectrum_000793, SpecPlus_000250, Spectrum2_000393, Spectrum3_000696, Spectrum4_001431, Spectrum5_000282, AC1NER77, BSPBio_002451, KBioGR_001902, KBioSS_001273, SPECTRUM200004, DivK1c_006346, SPBio_000605, CHEMBL1411329, KBio1_001290, KBio2_001273, KBio2_006409, KBio3_001671, CCG-38664, SDCCGMLS-0066427.P001, NCGC00095459-01, NCGC00095459-02, SR-05000002634, SR-05000002634-1, 9,12a-dihydroxy-2,3-dimethoxy-12-oxo-6,6a-dihydrochromeno[3,4-b]chromene-8-carboxylic acid


ID: 1550

chemical graph of compound 1550



InChIKey: OCJBOOLMMGQPQU-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4685
synonyms found at PubChem are:
1,4-DICHLOROBENZENE, p-Dichlorobenzene, 106-46-7, paradichlorobenzene, Paracide, Paramoth, para-Dichlorobenzene, Dichlorobenzene, Paranuggets, Santochlor, Paradow, Evola, Persia-perazol, p-Dichlorobenzol, p-Chlorophenyl chloride, Globol, p-Dichlorbenzol, Para crystals, Benzene, 1,4-dichloro-, Dichlorocide, Paradi, Di-chloricide, Paradichlorbenzol, PARA, PDCB, p-Diclorobenzene, 1,4-Dichloorbenzeen, p-Dichloorbenzeen, Paradichlorobenzol, 1,4-Dichlor-benzol, 1,4-Diclorobenzene, Benzene, p-dichloro-, dichloricide, Parazene, RCRA waste number U070, RCRA waste number U071, RCRA waste number U072, 1,4-dichloro-benzene, Para-zene, 4-Dichlorobenzene, NCI-C54955, p-DCB, Caswell No. 632, Kaydox, p-Dichlorbenzene, p-Dichlorbenzol [German], p-Dichloorbenzeen [Dutch], Paradichlorbenzol [German], UNII-D149TYB5MK, p-Diclorobenzene [Italian], PDB, NSC 36935, 1,4-chlorobenzene, CCRIS 307, 1,4-Dichloorbenzeen [Dutch], 1,4-Dichlor-benzol [German], 1,4-Diclorobenzene [Italian], Dichlorobenzene, para, HSDB 523, EINECS 203-400-5, RCRA waste no. D027, RCRA waste no. U072, EPA Pesticide Chemical Code 061501, D149TYB5MK, AI3-0050, AI3-00050, CHEMBL190982, CHEBI:28618, OCJBOOLMMGQPQU-UHFFFAOYSA-N, NCGC00094540-01, 1,3-Cyclohexadien-5-yne,1,4-dichloro-, DSSTox_CID_431, DSSTox_RID_75582, DSSTox_GSID_20431, 73513-56-1, C6H4Cl2, 1,4-dichlorbenzol, CAS-106-46-7, Dichlorobenzene, p-, 1,4 dichlorobenzene, Dichlorobenzene, 1,4-, diclorobenzene, p-dichlorobenzen, Moth Nuggets, p-dichloro-benzene, Benzene,4-dichloro-, 96384-17-7, Dichlorobenzene, solid, 1, 4-Dichlorobenzene, Spectrum_001891, ACMC-1BDGR, SpecPlus_000512, 1,3-Cyclohexadien-5-yne, 1,4-dichloro-, AC1Q3OEE, Benzene, 1,4-dichloro-, radical ion(1-), Spectrum2_001869, Spectrum3_000846, Spectrum4_000686, Spectrum5_002008, p-Dichlorbenzol(GERMAN), p-Dichloorbenzeen(DUTCH), Para-Dichlorobenzene,(S), WLN: GR DG, 1,4-Dichlorobenzene paste, EC 203-400-5, p-Diclorobenzene(ITALIAN), AC1L1IQ1, Dichlorobenzene, p-, solid, SCHEMBL5191, BSPBio_002431, KBioGR_001151, KBioSS_002421, SPECTRUM330055, KSC176S3J, BIDD:ER0278, DivK1c_006608, SPBio_001718, 1, 4-Dichloorbenzeen(DUTCH), 1,4-Dichlor-benzol(GERMAN), 1,4-Diclorobenzene(ITALIAN), DTXSID1020431, 1,4-Dichlorobenzene, >=99%, CTK0H6934, KBio1_001552, KBio2_002415, KBio2_004983, KBio2_007551, KBio3_001931, KS-00000VTW, MolPort-001-770-272, LS-58, ZINC388507, NSC36935, Tox21_111293, Tox21_200399, Tox21_300018, 1,4-Dichlorobenzene-UL-14C, neat, ANW-42346, BDBM50159263, c0593, CCG-39407, MFCD00000604, NSC-36935, STL445582, AKOS000120016, AS06944, MCULE-2384194593, NE10041, RL00286, RTR-032501, TRA0038301, UN 1592, 1,4-Dichlorobenzene (ACD/Name 4.0), 1,4-Dichlorobenzene (p-dichlorobenzene), NCGC00094540-02, NCGC00094540-03, NCGC00094540-04, NCGC00094540-05, NCGC00253934-01, NCGC00257953-01, 55232-43-4, CJ-03279, S679, SC-79050, ZB011558, Benzene,1-chloro-4-(chloro-38cl)-(9ci), KB-309476, TR-032501, D0687, FT-0606862, S0666, 1,4-Dichlorobenzene 10 microg/mL in Isooctane, C07092, 1,4-Dichlorobenzene 100 microg/mL in Methanol, 1,4-Dichlorobenzene 1000 ng/microl in Methanol, 1,4-Dichlorobenzene, SAJ first grade, >=99.0%, 177753-EP2272510A1, I01-6761, J-503986, 1,4-Dichlorobenzene, PESTANAL(R), analytical standard, F0001-0123, InChI=1/C6H4Cl2/c7-5-1-2-6(8)4-3-5/h1-4, UNII-F56X88UAJQ component OCJBOOLMMGQPQU-UHFFFAOYSA-N, Adipic acid, 1,3-butylene glycol copolymer, di(C14-C18) alkylcarboxylate, Hexanedioic acid, polymer with 1,3-butanediol, diesters with C14-18 fatty acids, 1,4-DICHLOROBENZENE (P-DICHLOROBENZENE) (SEE ALSO: 1,2-DICHLOROBENZENE (95-50-1)& 1,3-DICHLOROBENZENE (541-73-1)), 68890-93-7


ID: 1551

chemical graph of compound 1551



InChIKey: OCLOVRSVPZPWHE-CNIOFZSVSA-N
SMILES: C/C/1=C\C[C@@H]2[C@H](CC2(C)C)C(=C)CCC1OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 16667747
synonyms found at PubChem are:
caryophyllenyl acetate, Spectrum5_000107, BSPBio_003019, SPECTRUM300148, SCHEMBL12998374, OCLOVRSVPZPWHE-CNIOFZSVSA-N, CCG-38427


ID: 1552

chemical graph of compound 1552



InChIKey: OCOKWVBYZHBHLU-UHFFFAOYSA-N
SMILES: CC(C)COC(=O)OCN1C(=O)CN(CC1=O)CCN2CC(=O)N(C(=O)C2)COC(=O)OCC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5233
synonyms found at PubChem are:
sobuzoxane, Perazolin, 98631-95-9, MST-16, Sobuzoxane [INN:JAN], Sobuzoxanum [INN-Latin], Sobuzoxano [INN-Spanish], UNII-R1308VH37P, MST 16, BRN 6031322, R1308VH37P, NCGC00015954-02, 1,2-Bis(4-isobutoxycarbonyloxymethyl-3,5-dioxo-piperazin-1-yl)ethane, 4,4'-Ethylenebis(1-(hydroxymethyl)-2,6-piperazinedione) bis(isobutyl carbonate) (ester), Sobuzoxano, Sobuzoxanum, 4,4'-(1,2-Ethanediyl)bis(1-iso-butoxycarbonyloxmethyl-2,6-piperazinedione), Carbonic acid, 1,2-ethanediylbis((2,6-dioxo-4,1-piperazinediyl)methylene)bis(2-methylpropyl) ester, Perazolin (TN), Sobuzoxane (JAN), Lopac-S-4692, AC1L1JW6, AC1Q6KZ2, DSSTox_CID_25203, DSSTox_RID_80747, DSSTox_GSID_45203, Lopac0_001094, SCHEMBL18416, MLS002153414, CHEMBL1256871, DTXSID5045203, CHEBI:32136, CTK8G3131, HMS2230C04, HMS3263K10, HMS3369L07, Tox21_110265, Tox21_501094, ZINC22032147, Sobuzoxane, >=99% (HPLC), solid, AN-5343, API0008426, CCG-205171, LP01094, NCGC00015954-01, NCGC00015954-03, NCGC00015954-04, NCGC00094367-01, NCGC00094367-02, NCGC00261779-01, LS-52027, SMR001230790, CAS-98631-95-9, EU-0101094, D01404, S 4692, 33985-EP2272827A1, 33985-EP2275420A1, 33985-EP2295055A2, 33985-EP2295416A2, 33985-EP2295426A1, 33985-EP2295427A1, 33985-EP2298748A2, 33985-EP2298764A1, 33985-EP2298765A1, 33985-EP2298768A1, 33985-EP2305642A2, 33985-EP2311453A1, 33985-EP2311808A1, 33985-EP2311829A1, 631S959, A839107, SR-01000075401, SR-01000075401-2, 4,4'-(1,2-Ethanediyl)bis(1-isobutoxycarbonyloxymethyl-2,6-piperazinedione), (4,4'-(ethane-1,2-diyl)bis(2,6-dioxopiperazine-4,1-diyl))bis(methylene) isobutyl dicarbonate, [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,5-bis(oxidanylidene)piperazin-1-yl]ethyl]-2,6-bis(oxidanylidene)piperazin-1-yl]methyl 2-methylpropyl carbonate, [4-[2-[4-(2-Methylpropoxycarbonyloxymethyl)-3,5-dioxo-piperazin-1-yl]ethyl]-2,6-dioxo-piperazin-1-yl]methyl 2-methylpropyl carbonate, [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl 2-methylpropyl carbonate, [4-[2-[4-(isobutoxycarbonyloxymethyl)-3,5-dioxo-piperazin-1-yl]ethyl]-2,6-dioxo-piperazin-1-yl]methyl isobutyl carbonate, 4,4 inverted exclamation marka-(1,2-Ethanediyl)bis(1-iso-butoxycarbonylox-methyl-2,6-piperazinedione), carbonic acid [4-[2-[4-[[2-methylpropoxy(oxo)methoxy]methyl]-3,5-dioxo-1-piperazinyl]ethyl]-2,6-dioxo-1-piperazinyl]methyl 2-methylpropyl ester


ID: 1553

chemical graph of compound 1553



InChIKey: OCXSDHJRMYFTMA-KMFBOIRUSA-M
SMILES: CCOC1=C(C2=CC=CC=C2C=C1)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5282391
synonyms found at PubChem are:
Nafcillin sodium salt monohydrate, 7177-50-6, Nafcillin sodium monohydrate, Nafcil, NAFCILLIN SODIUM, Nafcillin sodium hydrate, UNII-49G3001BCK, Nafcillin (sodium monohydrate), Wy 3277, CHEBI:51919, 49G3001BCK, WY-3277, NCGC00017070-01, CAS-7177-50-6, DSSTox_CID_25570, DSSTox_RID_80967, DSSTox_GSID_45570, Nafcillin natrium-1-wasser, SMR000653476, Nafcillin sodium (USP), Naphthicillin, Nafcillin sodium [USAN:USP], sodium;(2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate, Unipen (TN), Monosodium (2S,5R,6R)-6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrate, Sodium Nafcillin Monohydrate, SCHEMBL65687, MLS001077264, MLS002222166, 985-16-0 (anhydrous), 147-52-4 (free acid), Nafcillin sodium salt monohydrat, CHEMBL1568276, DTXSID7045570, HY-B0555A, C21H21N2O5S.Na.H2O, MolPort-028-744-657, HMS1570J07, HMS2097J07, HMS2233C12, HMS3714J07, BCP17430, Tox21_110767, 3907AH, CN-466, MFCD01941128, s4042, AKOS025402388, Tox21_110767_1, AC-8800, CCG-220843, CS-2665, NCGC00273482-01, FT-0700019, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S-(2alpha,5alpha,6beta)), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S-(2alpha,5alpha,6beta))-, D00928, 6-(2-Ethoxy-1-naphthamido)penicillin monohydrate, nafcillin sodium pound Nafcillin sodium monohydrate pound(c), monohydrate of sodium salt of 6-(2-ethoxy-1-naphthamido)penicillanic acid, sodium 6beta-[(2-ethoxy-1-naphthoyl)amino]-2,2-dimethylpenam-3alpha-carboxylate hydrate, (2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt, sodium (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate, Sodium(2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatehydrate


ID: 1554

chemical graph of compound 1554



InChIKey: OCYSGIYOVXAGKQ-FVGYRXGTSA-N
SMILES: CNC[C@@H](C1=CC(=CC=C1)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 441279
synonyms found at PubChem are:
AC1L9AVO, [(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methylazanium chloride, Mydfrin, CHEBI:8094, AC1LCW6U, hydron; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol; chloride, PHENYLEPHRINE HYDROCHLORIDE, 61-76-7, Phenylephrine HCl, L-PHENYLEPHRINE HYDROCHLORIDE, (R)-Phenylephrine hydrochloride, Metaoxedrine chloride, Neosympatol, Synethenate, Almefrin, Consdrin, Emagrin, Fenilfar, Histabid, Idrianol, Lexatol, Oftalfrine, Phenistan, Pyristan, Stanephrin, Sucraphen, Synasal, Fenox, Alcon-efrin, meta-Sympatol, OP-Isophrin, Phenylephrine.HCl, Neo-Synesin 1, Neooxedrine chloride, Adrianol, Biomydrin, Neophryn, Prefrin, Rhinall, Consdrin hydrochloride, Isophrin hydrochloride, Vasosulf, Relief, Metaoxedrine hydrochloride, Neosynephrine hydrochloride, UNII-04JA59TNSJ, Op-Isophrin-Z, meta-Synephrine hydrochloride, Efricel, CCRIS 219, Levophenylephrine hydrochloride, Phenylephrine hydrochloride, l-, (-)-Phenylephrine hydrochloride, NCI-C55641, R-(-)-m-Synephrine hydrochloride, D-(-)-Phenylephrine hydrochloride, (R)-(-)-Phenylephrine hydrochloride, EINECS 200-517-3, m-Methylaminoethanolphenol hydrochloride, (R)-(-)-Phenylephrine (hydrochloride), 04JA59TNSJ, MLS000069696, Benzedrex Nasal Spray, Regular, (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride, l-1-(m-Hydroxyphenyl)-2-methyl-aminoethanol hydrochloride, NCGC00024257-04, 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol hydrochloride, SMR000058497, 1-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride, (-)-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride, (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol hydrochloride, DSSTox_CID_1142, (-)-alpha-Hydroxy-beta-(methylamino)ethyl-alpha-(3-hydroxybenzene) hydrochloride, Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride, (-)-, C9H13NO2.HCl, DSSTox_RID_75972, DSSTox_GSID_21142, Q-201561, Vazculep, (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride (R)-, Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, hydrochloride, (-)-, Sudafed PE, Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride, (alphaR)-, CAS-61-76-7, L(-)-Phenylephrine hydrochloride, Incostop, 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride, SR-01000075286, Phenylephrine hydrochloride [USP:JAN], Vicks Sinex Vapospray, Neo-Synephrine (TN), Phenylephrine hydrochloride [USAN:JAN], PubChem23988, Vicks Sinex Nasal Spray, AC1NR4GJ, Opera_ID_1786, neosynephrine hydrocholride, Afrin 4 Hour Nasal Spray, D0D7QO, EC 200-517-3, SCHEMBL24654, MLS006012005, 59-42-7 (Parent), SPECTRUM1500483, L-Pheny lephrine Hydrochloride, Phenylephrine hydrochloride gel, Phenylephrine hydrochloride,(S), CHEMBL1200339, DTXSID3021142, VEN-308, MolPort-003-666-260, OCYSGIYOVXAGKQ-FVGYRXGTSA-N, HMS1920H08, Pharmakon1600-01500483, BCP23410, HY-B0471, Tox21_110897, Tox21_201261, Tox21_302846, Tox21_500920, CCG-39113, GL9617, MFCD00012605, NSC757273, s2569, AKOS022190146, Tox21_110897_1, CS-2585, LP00920, LS-1454, NSC-757273, Phenylephrine hydrochloride (JP17/USP), NCGC00024257-08, NCGC00094231-01, NCGC00256496-01, NCGC00258813-01, NCGC00261605-01, BCP0726000237, AB2000665, (R)-(-)-Phenylephrine hydrochloride, powder, EU-0100920, P0398, ST24035423, VU0239753-6, D00511, P 6126, 10% phenylephrine HCl cream, Solvay/SLA Pharma, 20% phenylephrine HCl cream, Solvay/SLA Pharma, Phenylephrine hydrochloride gel (fecal incontinence), SR-01000075286-1, (R)-(-)-Phenylephrine hydrochloride, analytical standard, UNII-O2VT86KV7E component OCYSGIYOVXAGKQ-FVGYRXGTSA-N, 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride, (R)-(-)-Phenylephrine hydrochloride, tested according to Ph.Eur., (R)-3-hydroxy-a-[(methylamino)methyl]-benzenemethanol hydrochloride, (-)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol, hydroc hloride, (-)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol, hydrochloride, (R)-(-)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride, Benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, hydrochloride,(aR)-, Phenylephrine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride (1:1), (alphaR)-, Phenylephrine hydrochloride gel (fecal incontinence), SLA Pharma/Ventrus Biosciences, Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Phenylephrine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 50741-76-9, 644-22-4, 827-62-3, Phenylephrine hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard


ID: 1555

chemical graph of compound 1555



InChIKey: ODBRNZZJSYPIDI-VJXVFPJBSA-N
SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(C(=C(C=C3O2)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 114776
synonyms found at PubChem are:
Isoorientin, Homoorientin, 4261-42-1, Luteolin-6-C-glucoside, UNII-A37342TIX1, Luteolin 6-C-glucoside, Luteolin-6-C-beta-D-glucoside, CHEBI:17965, A37342TIX1, 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one, (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-6-yl]-D-glucitol, Homoori-entin, AC1L3FXW, AC1Q6BBI, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one, SCHEMBL23761, MLS002473101, Luteolin 6-C-|A-D-glucoside, CHEMBL239559, Luteolin 6-C-beta-D-glucoside, Isoorientin, analytical standard, Isoorientin, >=98% (HPLC), luteolin-6-C-B-D-glucopyranoside, MolPort-006-823-901, ODBRNZZJSYPIDI-VJXVFPJBSA-N, HMS2225D20, HY-N0767, ZINC4349262, Isoorientin, >=98.0% (HPLC), MFCD00017433, AKOS015896766, CCG-208392, CS-7515, 2-(3,4-dihydroxyphenyl)-6-b-d-glucopyranosyl-5,7-dihydroxy-4h-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-, NCGC00163566-01, CC-29387, SC-65304, SMR001397203, LS-193057, FT-0603655, X1168, A18799, C01821, 261H421, C-22458, I07-0228, Q-100474, Isoorientin, primary pharmaceutical reference standard, 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-6-b-D-glucopyranosyl-5,7-dihydroxy-, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one


ID: 1556

chemical graph of compound 1556



InChIKey: ODCWYMIRDDJXKW-UHFFFAOYSA-N
SMILES: CCNC1=NC(=NC(=N1)Cl)NCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5216
synonyms found at PubChem are:
simazine, 122-34-9, Gesatop, Princep, Simanex, Aquazine, Batazina, Herbazin, Symazine, Tafazine, Taphazine, Amizine, Bitemol, Gesapun, Herbex, Herboxy, Printop, Radocon, Radokor, Simadex, Zeapur, Herbazin 50, Primatol S, Aktinit S, Hungazin DT, Gesaran, Premazine, Simazin, Simazine 80W, Gesatop 50, Tafazine 50-W, Cekuzina-S, Primatel S, CAT (herbicide), 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine, Yrodazin, Azotop, Simatsin-neste, Herbatoxol S, Triazine A 384, Geigy 27,692, 6-Chloro-N,N'-diethyl-1,3,5-triazine-2,4-diamine, 2,4-Bis(ethylamino)-6-chloro-s-triazine, 2-Chloro-4,6-bis(ethylamino)-s-triazine, Bitemol S 50, Cekusima, Batazine FLO, 1,3,5-Triazine-2,4-diamine, 6-chloro-N,N'-diethyl-, Herbex (pesticide), Tafazine (VAN), 2-Chloro-4,6-bis(ethylamino)-1,3,5-triazine, Caswell No. 740, Framed, A 2079, H 1803, W 6658, 2,4-Bis(ethylamino)-6-chloro-1,3,5-triazine, G 27692, UNII-SG0C34SMY3, Simazine [ANSI:BSI:ISO], Bitemol S-50, CCRIS 1469, HSDB 1765, s-Triazine, 2-chloro-4,6-bis(ethylamino)-, EINECS 204-535-2, NSC 25999, 1-Chloro-3,5-bis(ethylamino)-2,4,6-triazine, G-27692, EPA Pesticide Chemical Code 080807, BRN 0010895, SG0C34SMY3, AI3-51142, CHEBI:27496, ODCWYMIRDDJXKW-UHFFFAOYSA-N, 6-Chloro-N,N'-diethyl-[1,3,5]triazin-2,4-diamine, 2,4-Bis(aethylamino)-6-chlor-1,3,5-triazin [German], 1,3,5-Triazine-2,4-diamine, 6-chloro-N2,N4-diethyl-, NCGC00094524-01, DSSTox_CID_1268, DSSTox_RID_76048, DSSTox_GSID_21268, Herbazin-50, 6-chloro-2-N,4-N-diethyl-1,3,5-triazine-2,4-diamine, [6-chloro-4-(ethylamino)(1,3,5-triazin-2-yl)]ethylamine, 6-chloro-N(2),N(4)-diethyl-1,3,5-triazine-2,4-diamine, 39291-64-0, CAS-122-34-9, cekuzinas, permazine, Herboxydiene, Printrex, Simatox, Simazat, Cekusan Gesatop, Princep 4G, Princep 4L, Simazine 50, Aquazine 90WDG, Caliber 90, Gesatop-50, Princep 80W, Triazine A384, Sim-Trol 4L, Princep Caliber 90, Spectrum_001809, SpecPlus_000400, Enamine_005673, AC1L1JUU, Spectrum2_001879, Spectrum3_000820, Spectrum4_000660, Spectrum5_001950, 2,4-Bis(aethylamino)-6-chlor-1,3,5-triazin, Oprea1_871264, SCHEMBL37774, 1-Chloro-3,4,6-triazine, BSPBio_002319, KBioGR_001039, KBioSS_002302, Simazine, analytical standard, SPECTRUM330028, BIDD:ER0337, DivK1c_006496, SPBio_001758, AC1Q31I4, AC1Q31I5, s-Triazine,6-bis(ethylamino)-, CHEMBL1605837, DTXSID4021268, CTK8E3500, KBio1_001440, KBio2_002300, KBio2_004868, KBio2_007436, KBio3_001819, MolPort-001-793-790, ZINC121575, NSC25999, Tox21_111291, Tox21_202378, Tox21_300748, BBL001812, CCG-39417, LS-664, NSC-25999, SBB056728, STK386441, 2-Chloro-4,6-di(ethylamino)triazine, 2-Chloro-4,6-bis(ethylamino)triazine, 4,6-Bis(ethylamino)-2-chlorotriazine, AKOS003629500, AKOS003630617, Tox21_111291_1, KS-5070, MCULE-8279853852, Simazine 10 microg/mL in Acetonitrile, Simazine 10 microg/mL in Ethylacetate, WLN: T6N CN ENJ BM2 DM2 FG, IDI1_007908, Simazine 100 microg/mL in Acetonitrile, NCGC00094524-02, NCGC00094524-03, NCGC00094524-04, NCGC00094524-05, NCGC00094524-06, NCGC00094524-07, NCGC00094524-09, NCGC00254653-01, NCGC00259927-01, AC-12676, AJ-11768, AN-43430, O396, QC-11277, SC-14192, ST011993, ZB004179, TR-003586, 6-Chloro-N,N'-diethyl-2,4-diaminetriazine, FT-0603326, s-Triazine, 2,4-bis(ethylamino)-6-chloro-, Simazine, PESTANAL(R), analytical standard, T7353, 1-Chloro-3,5-Bisethylamino-2,4,6-Triazine, 2,4-Di(ethylamino)-6-chloro-1,3,5-triazine, 2-chloro-4,6-bis-ethylamino-1,3,5-triazine, 3584-EP2289891A2, C11172, 30497-EP2272847A1, 30497-EP2284170A1, 30497-EP2292088A1, 30497-EP2305642A2, 30497-EP2311835A1, 33280-EP2274983A1, 33280-EP2305655A2, 33280-EP2305658A1, 33280-EP2305662A1, 33280-EP2311815A1, 33280-EP2371823A1, Chloro-4,6-bis( ethylamino)-s-triazine, 124900-EP2295426A1, 124900-EP2295427A1, J-004790, 1,5-Triazine-2,4-diamine, 6-chloro-N,N'-diethyl-, 2,4-Diamine-6-chloro-N,N'-diethyl-1,3,5-triazine, BRD-K01416914-001-02-3, N,N'-diethyl-6-chloro-[1,3,5]triazine-2,4-diamine, 2-CHLORO-4,6-BIS(ETHYLAMINO)-sym-TRIAZINE, 80%, 6-Chloro-N,N'-diethyl-1,3,5-triazine-2,4-diyldiamine, [4-chloro-6-(ethylamino)(1,3,5-triazin-2-yl)]ethylamine, Simazine solution, 100 mug/mL in methanol, PESTANAL(R), analytical standard, 11141-20-1, 119603-94-0, 12764-71-5


ID: 1557

chemical graph of compound 1557



InChIKey: ODFJOVXVLFUVNQ-UHFFFAOYSA-N
SMILES: CC(=O)NC1=C(C=CC(=C1)[As](=O)(O)O)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"
"KA Teske" "R Robert" "Y Luo" "JW Hanrahan" "GW Carlile" "DY Thomas" "D Zhang"


CID is 1985
synonyms found at PubChem are:
acetarsol, Acetarsone, Acetphenarsine, Amoebal, Arsaphen, Dynarsan, Stovarsol, Mexyl, 97-44-9, Arsonine, Disparicida, Ginarsol, Gynoplix, Kharophen, Kubarsol, Limarsol, Malagride, Monargan, Osarsole, Osvarsan, Osvarson, Pallicid, Spirocid, Spirozid, Stovarsal, Stovarsolan, Vagisept, Vagoflor, Amarsan, Devegan, Nilacid, Oralcid, Orarsan, Osarsal, Osarsol, Paroxyl, Goyl, Fourneau 190, Acetarsolum, Acetarsolo, Chrlich 594, Ehrlich 594, Osarsolum, Sanogyl, N-Acetyl-4-hydroxy-m-arsanilic acid, Acetarsolo [DCIT], Acetarsol [INN:BAN], 3-Acetamido-4-hydroxybenzenearsonic acid, 3-Acetylamino-4-hydroxyphenylarsonic acid, Acetarsolum [INN-Latin], C8H10AsNO5, 3-Acetamido-4-hydroxy-phenylarsonic acid, UNII-806529YU1N, Acetamino-hydroxyphenyl-arsonsaeure, 190 F, F 190, m-ARSANILIC ACID, N-ACETYL-4-HYDROXY-, EINECS 202-582-3, NSC 13160, 3-Acetamido-4-hydroxyphenylarsonsaeure, BRN 2941984, AI3-16141, MLS000028389, MLS000736495, NSC13160, 806529YU1N, SVC, 3-Acetamido-4-hydroxyphenylarsonic acid, NCGC00094812-01, SMR000058626, (3-acetamido-4-hydroxyphenyl)arsonic acid, DSSTox_CID_25847, DSSTox_RID_81169, DSSTox_GSID_45847, Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)-, Arsonic acid, [3-(acetylamino)-4-hydroxyphenyl]-, S.V.C., WLN: Q-AS-QO&R DQ CMV1, WLN: Q-AS-QO & R DQ CMV1, CAS-97-44-9, [3-(Acetylamino)-4-hydroxyphenyl]arsonic acid, Acetarsone [INN:NF], Acetarsol (INN), Acetarsol (Acetarsone), Spectrum_000588, Acetarsone, >=99%, Opera_ID_176, Spectrum2_000104, Spectrum3_000595, Spectrum4_000384, Spectrum5_000640, AC1L1CO2, BSPBio_002070, KBioGR_000907, KBioSS_001068, 3-16-00-01132 (Beilstein Handbook Reference), MLS001148100, DivK1c_000002, SCHEMBL156373, SPECTRUM1500616, SPBio_000088, AC1Q5A60, CHEMBL1330792, DTXSID9045847, HMS500A04, KBio1_000002, KBio2_001068, KBio2_003636, KBio2_006204, KBio3_001570, NSC3247, CHEBI:135135, MolPort-003-665-580, NINDS_000002, HMS1921K13, HMS2092E06, HMS2235C23, HMS3371H07, Pharmakon1600-01500616, 64046-96-4 (calcium salt), NSC-3247, Tox21_111336, 7891AF, CCG-39708, NSC-13160, NSC757386, AKOS015894435, Tox21_111336_1, KS-1320, NSC-757386, IDI1_000002, 2-ACETAMINOPHENOL-4-ARSONIC ACID, 5892-48-8 (mono-hydrochloride salt), NCGC00094812-02, NCGC00094812-03, NCGC00094812-05, LS-21674, NCI60_002818, 64046-96-4 (unspecified calcium salt), SBI-0051558.P002, (3-acetamido-4-hydroxy-phenyl)arsonic acid, FT-0621732, 55588-51-7 (unspecified hydrochloride salt), D07110, 33425-EP2274983A1, 33425-EP2305655A2, 33425-EP2311815A1, 33425-EP2371823A1, AB00052127_12, AB00052127_13, SR-01000695452, I04-9258, SR-01000695452-3, W-204159, Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)- (9CI)


ID: 1558

chemical graph of compound 1558



InChIKey: ODHSWYNEXJIJEI-ZHVFSVHYSA-N
SMILES: CC(=O)OC1[C@@]2(C=C3C(CC[C@@]4(C3CC(=O)O[C@H]4C5=COC=C5)C)[C@@](C2=O)([C@H](C1(C)C)CC(=O)OC)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708546
synonyms found at PubChem are:
HUMILIN A, KBio2_001056, Spectrum_000576, SpecPlus_000089, Spectrum2_000245, Spectrum3_000026, Spectrum4_001308, Spectrum5_000095, BSPBio_001691, KBioGR_001715, KBioSS_001056, DivK1c_006185, SPBio_000030, CHEMBL3039257, KBio1_001129, KBio2_003624, KBio2_006192, KBio3_000811, NCGC00179083-01


ID: 1559

chemical graph of compound 1559



InChIKey: ODJLBQGVINUMMR-HZXDTFASSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@]1(CC[C@@H]2C4=CC(=O)OC4)O)CC[C@]5([C@@]3(CC[C@@H](C5)O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6185
synonyms found at PubChem are:
strophanthidin, Convallatoxigenin, Strophanthidine, Corchsularin, Corchorgenin, Corchoside A aglycon, Erysimupicrone, Corchorin, k-Strophanthidin, Strophanthidin K, 66-28-4, Apocynamarin, Erysimupikron, Cymarigenin, k-Strophanthidine, Cyanotoxin, 5beta-Hydroxy-19-oxodigitoxigenin, Antibiotic XS-89, NSC-86078, 3beta,5,14-Trihydroxy-19-oxo-5beta-card-20(22)-enolide, UNII-W5O632DN33, XS-89, 5-beta-Hydroxy-19-oxodigitoxigenin, NSC86078, EINECS 200-626-6, NSC 86078, BRN 0097859, CHEBI:38178, W5O632DN33, 3,5,14-Trihydroxy-19-oxocard-20(22)-enolide, 3-beta,5,14-Trioxy-19-oxo-carden-(20:22)-olid [German], 3-beta,5,14-Trioxy-19-oxo-digen-(20:22)-olid [German], (3beta,5beta)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide, 19-Oxo-cardogenen-(20:22)-triol-(3-beta,5,14) [German], 3-beta,5,14-Trihydroxy-19-oxo-5-beta-card-20(22)-enolide, Cymarigenen, Strophantidine, Apocymarin, Cynotoxin, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,5,14-TRIHYDROXY-19-OXO-, (1S,2S,5S,7S,11S,10R,14R,15R)-5,7,11-trihydroxy-15-methyl-14-(5-oxo(3-2-hydrof uryl))tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadecane-2-carbaldehyde, (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, 5.beta.-Hydroxy-19-oxodigitoxigenin, Prestwick_117, kappa-Strophanthidine, Corchoside A, aglycon, Prestwick0_000710, Prestwick1_000710, Prestwick2_000710, Prestwick3_000710, AC1L1LZ3, BSPBio_000899, 5-18-05-00126 (Beilstein Handbook Reference), MLS002153969, SCHEMBL240582, 3-beta,5,14-Trioxy-19-oxo-carden-(20:22)-olid, 3-beta,5,14-Trioxy-19-oxo-digen-(20:22)-olid, SPBio_002820, BPBio1_000989, CHEMBL111743, 19-OXO-CARDOGENEN-(20:22)-TRIOL-(3-beta,5,14), MolPort-002-526-048, ODJLBQGVINUMMR-HZXDTFASSA-N, HMS1570M21, HMS2097M21, HMS2233O14, ZINC3875425, LMST01120005, MFCD00046266, AKOS024280415, NCGC00142399-02, 1397-98-4, LS-52516, NCI60_041903, SMR001233308, ST032738, C19988, C-49284, SR-01000838893, SR-01000838893-2, BRD-K84595254-001-03-0, BRD-K84595254-001-10-5, 3beta,5,14-Trihydroxy-19-oxo-5beta,20(22)-cardenolide, 5.beta.-Card-20(22)-enolide,5,14-trihydroxy-19-oxo-, UNII-O6I3I9267L component ODJLBQGVINUMMR-HZXDTFASSA-N, WLN: L E5 B666TJ AVH E1 IQ MQ OQ F- DT5OV EHJ, 3.beta.,14-Trihydroxy-19-oxo-5.beta.-card-20(22)-enolide, 5beta-Card-20(22)-enolide, 3beta,5,14-trihydroxy-19-oxo-, (3.beta.,5.beta.)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide, 5beta-Card-20(22)-enolide, 3beta,5,14-trihydroxy-19-oxo- (8CI), Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3-beta,5-beta)-, Card-20(22)-enolide,5,14-trihydroxy-19-oxo-, (3.beta.,5.beta.)-, Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3-beta,5-beta)- (9CI), 11023-66-8, 1398-86-3


ID: 1560

chemical graph of compound 1560



InChIKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5790
synonyms found at PubChem are:
floxuridine, 50-91-9, 2'-Deoxy-5-fluorouridine, 5-Fluorodeoxyuridine, Fluorodeoxyuridine, Floxuridin, FUDR, Deoxyfluorouridine, Fluoruridine deoxyribose, 5-Fluoro-2'-deoxyuridine, FdUrd, Floxiridina, Floxuridinum, 5FdU, 5 Fluorodeoxyuridine, 5-fluoro-1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1h,3h)-dione, 5-Fluoro-2-desoxyuridine, Floxuridinum [INN-Latin], FDUR, Floxiridina [INN-Spanish], 5-Fluoro-2-deoxyuridine, beta-5-Fluoro-2'-deoxyuridine, 5-FdUrd, 5-Fluorouracil deoxyriboside, 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil, Uridine, 2'-deoxy-5-fluoro-, 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil, UNII-039LU44I5M, 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione, CHEBI:60761, HSDB 3227, 5-Fluorouracil 2'-deoxyriboside, 5-FUDR, EINECS 200-072-5, (+)-5-fluorodeoxyuridine, CHEMBL917, FUDR (TN), BRN 0090221, AI3-50691, MLS000069439, (+)-5-fluoro-2'-deoxyuridine, 039LU44I5M, Uridine, 2'-deoxy-5'-fluoro-, NCGC00023722-05, SMR000059051, NSC 27640, NSC-27640, DSSTox_CID_3057, 5-Fluor-1-(beta-2'-deoxyribofuranosyl)pyrimidin-2,4(1H,3H)-dion [Czech], Ro 5-0360, DSSTox_RID_76855, DSSTox_GSID_23057, Uridine, 2'-deoxy-5-fluoro, (+)-5-Fluoro-2 -deoxyuridine, CAS-50-91-9, 1-[(4S,2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,3-dihydropyri midine-2,4-dione, 5-Fluoro-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione, FdU, Floxuridine [USAN:INN], 5-Fluoro-2'-deoxy-beta-uridine, floxidine, Fluoxuridine, NSC27640, Floxuridine [USAN:USP:INN], 5-floxuridine, Floxuridine,(S), 5-Fluoro-dUrd, Sterile fudr (TN), Floxuridine (Fludara), PubChem21054, Floxuridine (USP/INN), Opera_ID_1559, Floxuridine/5-fluorouracil, 2-deoxy-5'-fluorouridine, 2;-Deoxy-5-fluorouridine, D06EGK, D0TS1Z, Epitope ID:138108, AC1Q77TE, SCHEMBL4424, 2''-deoxy-5-fluorouridine, 2'-deoxy-5-fluoro uridine, 5-fluoro-2''-deoxyuridine, 5-24-06-00291 (Beilstein Handbook Reference), KSC593G8F, MLS002695934, MLS006011768, 5-fluoro-2''-Deoxy-uridine, 2'-deoxy-5-fluoro-d-uridine, AC1L1L58, GTPL4801, DTXSID3023057, CTK4J3382, MolPort-002-507-300, ODKNJVUHOIMIIZ-RRKCRQDMSA-N, HMS2090I12, HMS2230N22, HMS3715A11, BCP02871, HY-B0097, KS-000002EU, ZINC3813010, Tox21_110892, 5-Fluor-1-(beta-2'-deoxyribofuranosyl)pyrimidin-2,4(1H,3H)-dion, ANW-31161, BBL033765, BDBM50340678, CF-072, MFCD00006530, s1299, STK801909, AKOS005622662, Tox21_110892_1, BCP9000691, CCG-220965, CS-1827, DB00322, MCULE-4890053166, PS-7520, RP28738, SRI-9246-15, SRI-9246_18, uridine, 2-18O-2'-deoxy-5-fluoro-, uridine, 3-15N-2'-deoxy-5-fluoro-, NCGC00023722-03, NCGC00023722-06, NCGC00023722-08, uridine, 5'-18O-2'-deoxy-5-fluoro-, AC-16391, AJ-45692, BR-24802, CJ-10772, CPD000059051, SAM002548946, SC-18561, ST056942, BCP0726000269, AB0069044, DB-020996, LS-160820, TL8003380, D2235, uridine, 2,5'-18O2-2'-deoxy-5-fluoro-, EN300-52649, C11736, D04197, J10098, S-2808, 15184-EP2272827A1, 15184-EP2275420A1, 15184-EP2295055A2, 15184-EP2295416A2, 15184-EP2295426A1, 15184-EP2295427A1, 15184-EP2298748A2, 15184-EP2298764A1, 15184-EP2298765A1, 15184-EP2298768A1, 15184-EP2305642A2, 15184-EP2311453A1, 15184-EP2311808A1, 15184-EP2311829A1, 15184-EP2311840A1, 15184-EP2311842A2, 15184-EP2316832A1, 15184-EP2316833A1, 006F530, 124816-EP2295426A1, 124816-EP2295427A1, SR-01000000001, J-700034, SR-01000000001-2, BRD-K47832606-001-26-9, BRD-K47832606-001-30-1, 5-Fluoro-2'-deoxyuridine, thymidylate synthase inhibitor, Z802671482, 1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil, Floxuridine, United States Pharmacopeia (USP) Reference Standard, 5-Fluoro-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione, 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 136353-77-0, 136353-81-6, 136353-85-0, 396726-50-4, 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, 5-FUdR|||5-Fluorodeoxyuridine|||5-Fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione


ID: 1561

chemical graph of compound 1561



InChIKey: ODKSFYDXXFIFQN-BYPYZUCNSA-N
SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6322
synonyms found at PubChem are:
L-arginine, arginine, 74-79-3, L-(+)-Arginine, L-Arg, L(+)-Arginine, H-Arg-OH, (S)-2-Amino-5-guanidinopentanoic acid, (L)-Arginine, Arginina, ARGININE, L-, L-Arginin, Arginine (VAN), Polyarginine, Argivene, Detoxargin, Levargin, Minophagen A, Argininum [INN-Latin], Arginina [INN-Spanish], L-Ornithine, N5-(aminoiminomethyl)-, Poly(L-arginine), Argamine, L-alpha-Amino-delta-guanidinovaleric acid, 1-Amino-4-guanidovaleric acid, CCRIS 3609, L-Arginine, homopolymer, NSC 206269, arg, Arginine [USAN:INN], HSDB 1429, AI3-24165, UNII-94ZLA3W45F, (S)-2-Amino-5-guanidinovaleric acid, BRN 1725413, CHEBI:16467, (S)-2-Amino-5-((aminoiminomethyl)amino)pentanoic acid, L-Norvaline, 5-((aminoiminomethyl)amino)-, (S)-(+)-arginine, EINECS 200-811-1, 2-amino-5-guanidinovaleric acid, CHEMBL1485, (2S)-2-amino-5-guanidinopentanoic acid, (S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid, 94ZLA3W45F, (2S)-2-amino-5-carbamimidamidopentanoic acid, Pentanoic acid, 2-amino-5-((aminoiminomethyl)amino)-, (S)-, L-a-Amino-d-guanidinovaleric acid, ODKSFYDXXFIFQN-BYPYZUCNSA-N, (2S)-2-amino-5-(carbamimidamido)pentanoic acid, L-Arginine, monohydrochloride, (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid, Arginine HCl, Arginine (L-Arginine), (2S)-2-amino-5-guanidino-pentanoic acid, L-Norvaline, 5-[(aminoiminomethyl)amino]-, DSSTox_CID_21056, DSSTox_RID_79618, DSSTox_GSID_41056, R-gene 10, C6H14N4O2, Argininum, Pentanoic acid, 2-amino-5-[(aminoiminomethyl)amino]-, (S)-, CAS-74-79-3, Arginine [USP:INN], 2-Amino-5-Guanidnovaleric Acid, NSC203450, 3h-l-arginine, L-Arginine, labeled with tritium, 1laf, NCGC00015064-02, (S)-Arginine, L(+) arginine, L-Aryginine,(S), H-Arg, L-(+) arginine, L(+)-Arginine;, PubChem7933, L-Arginine (9CI), Arginine (USP/INN), Tocris-0663, L-Arginine (JP17), Lopac-A-5006, Arginine, L- (8CI), bmse000029, bmse000899, bmse000919, D0F5DO, D0O3VV, Epitope ID:140084, EC 200-811-1, AC1L1M9R, AC1Q4U8L, AC1Q4U8M, AC1Q4U8N, SCHEMBL1791, 2-amino-5-guanidinovalerate, Lopac0_000077, Arginine hydrochloride(USAN), GTPL721, 4-04-00-02648 (Beilstein Handbook Reference), L-a-Amino-d-guanidinovalerate, L-Amino-4-guanidovaleric acid, US9138393, L-Arginine, US9144538, L-Arginine, 1-Amino-4-guanidovalerlic acid, DTXSID6041056, BDBM21959, CTK7D2126, R-Gene 10 (Pharmacia Corp.), L-Arginine, 99%, FCC, FG, MolPort-000-000-568, MolPort-006-109-239, 26982-20-7 (hydrochloride), BDBM181132, HMS3260O15, N5-(aminoiminomethyl)-L-Ornithine, HY-N0455, ZINC1532525, L-Arginine, Vetec(TM), 98.5%, Tox21_113046, Tox21_500077, AC-083, ANW-36527, L-alpha-Amino-delta-guanidinovalerate, L-Arginine, reagent grade, >=98%, MFCD00002635, AKOS006239069, AKOS015854096, Tox21_113046_1, AM81500, CCG-204172, DB00125, LP00077, MCULE-5108123240, RP23641, RTR-032432, L-Arginine, 99%, natural, FCC, FG, (s)-2-amino-5-guanidino-pentanoic acid, 5-[(aminoiminomethyl)amino]-L-Norvaline, NCGC00015064-01, NCGC00024715-01, NCGC00024715-02, NCGC00024715-03, NCGC00024715-04, NCGC00024715-05, NCGC00260762-01, 25212-18-4, 4455-52-1, AJ-26775, AN-16154, AN-20586, AS-14190, BC204045, K277, KB-53124, LS-21576, SC-06613, L-Arginine, BioUltra, >=99.5% (NT), SBI-0207062.P001, AB0014136, AB1002666, LS-170346, LS-185750, ST2414597, TR-032432, A0526, A7079, EU-0100077, FT-0627695, L-Arginine, SAJ special grade, >=98.0%, A 5006, A50124, C00062, D02982, L-Arginine, Vetec(TM) reagent grade, >=98%, M02981, Y-8965, 14932-EP2316830A2, AB00374192_03, L-Arginine-L-Glutamate 2-Amino-Pentanedoic Acid, Norvaline, 5-[(aminoiminomethyl)amino]-, (L)-, 002A635, A837397, SR-01000075479, SR-01000597671, (S)-2-amino-5-[(aminoiminomethyl)amino]-Pentanoate, (S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate, SR-01000075479-1, SR-01000597671-1, W-104410, (S)-2-amino-5-[(aminoiminomethyl)amino]-Pentanoic acid, Arginine, European Pharmacopoeia (EP) Reference Standard, (2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid, 7F15B0C7-356D-45D7-AC33-03AEE4394A0E, S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid, UNII-FL26NTK3EP component ODKSFYDXXFIFQN-BYPYZUCNSA-N, (2S)-2-azanyl-5-[bis(azanyl)methylideneamino]pentanoic acid, L-Arginine, United States Pharmacopeia (USP) Reference Standard, L-Arginine, Pharmaceutical Secondary Standard; Certified Reference Material, 104352-01-4, 1332377-47-5, 142-49-4, 154605-63-7, 154605-67-1, 667422-95-9, InChI=1/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s, L-, L-Arginine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%, L-Arginine, PharmaGrade, Ajinomoto, EP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture, CPSS, Protonated arginine, ARGININE, CONJUGATE MONOACID, L-, AC1L1G1Y, 17806-42-7, LS-21587, (2S)-2-amino-5-(diaminomethylideneazaniumyl)pentanoate


ID: 1562

chemical graph of compound 1562



InChIKey: ODNDMTWHRYECKX-XFULWGLBSA-N
SMILES: CCCN(CCC)[C@@H]1CCC2=C(C1)C=C(C=C2)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957554
synonyms found at PubChem are:
R-(+)-7-Hydroxy-DPAT hydrobromide, EU-0100569, CHEMBL1256389, MolPort-042-665-587, Tox21_500569, CCG-221873, LP00569, (R)-(+)-7-Hydroxy-DPAT hydrobromide, NCGC00093953-01, NCGC00261254-01, H-168, R(+)-7-Hydroxy-dipropylaminotetralin hydrobromide, SR-01000075926, SR-01000075926-1


ID: 1563

chemical graph of compound 1563



InChIKey: ODUOJXZPIYUATO-UHFFFAOYSA-N
SMILES: CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 107751
synonyms found at PubChem are:
Racecadotril, 81110-73-8, Acetorphan, Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate, CADOTRIL, REDOTIL, Tiorfan, Racecadotril [INN], ZEDOTT, Racecadotril (Acetorphan), (+/-)-ACETORPHAN, Racecadotril (INN), CPD000449320, (+-)-N-(2-((Acetylthio)methyl)-1-oxo-3-phenylpropyl)glycine phenylmethyl ester, Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, Glycine, N-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-,phenylmethyl ester [CAS], C21H23NO4S, (RS)-BENZYL N-[3-(ACETYLTHIO)-2-BENZYLPROPANOYL]GLYCINATE, benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate, (+-)-N-(alpha-(Mercaptomethyl)hydrocinnamoyl)glycine, benzyl ester, acetate (ester), 2-[[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]amino]acetic acid (phenylmethyl) ester, Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, (+-)-, SMR000449320, SR-01000759384, Racecadotril [INN:BAN], Hidrasec (TN), Prestwick_926, Tiorfan (TN), PubChem18214, Prestwick0_000626, Prestwick1_000626, Prestwick2_000626, Prestwick3_000626, AC1L32OP, AC1Q68VE, BSPBio_000592, MLS000758279, MLS001423958, MLS006010032, SCHEMBL373243, SPBio_002811, BPBio1_000652, benzyl n-[3-(acetylsulfanyl)-2-benzylpropanoyl]glycinate, CHEMBL2103772, CHEBI:91508, CTK8B4403, Racecadotril, >=98% (HPLC), MolPort-005-935-306, ODUOJXZPIYUATO-UHFFFAOYSA-N, HMS1569N14, HMS2051K05, HMS2090L07, HMS2096N14, HMS2232F17, HMS3370B22, HMS3393K05, HMS3656C10, HMS3713N14, Pharmakon1600-01502331, BCP22637, KS-00000H0Z, ANW-44918, MFCD00865520, NSC759828, s2503, AKOS015894948, AB07493, AC-1133, AN-6545, CCG-100764, CCG-213824, CS-1127, DB11696, HS-0029, NC00014, NSC-759828, NCGC00179511-01, NCGC00179511-04, AK-72817, BC208829, BR-72817, CC-34204, HY-17399, LS-72246, SAM001247060, SC-46074, AB0007509, AB2000608, AX8150197, TR-025540, FT-0602523, R0103, ST24031603, D08464, W-5137, 110R738, A840045, C-21435, benzyl (3-(acetylthio)-2-benzylpropanoyl)glycinate, I06-0039, SR-01000759384-4, SR-01000759384-5, Benzyl N-[3-(Acetylthio)-2-benzylpropionyl]glycinate, BRD-A08187463-001-03-8, N-[3-Acetylthio-2-benzylpropanoyl]glycine benzyl ester, N-(3-acetylmercapto-2-benzylpropanoyl)glycine benzyl ester, N-[3-(Acetylthio)-2-benzylpropionyl]glycine Benzyl Ester, Racecadotril, European Pharmacopoeia (EP) Reference Standard, benzyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate, benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenyl-propanoyl]amino]acetate, (2-ACETYLSULFANYLMETHYL-3-PHENYL-PROPIONYLAMINO)-ACETIC ACID BENZYL ESTER, (phenylmethyl) 2-[[2-(ethanoylsulfanylmethyl)-3-phenyl-propanoyl]amino]ethanoate, Racecadotril for peak identification, European Pharmacopoeia (EP) Reference Standard, 81110-60-3


ID: 1564

chemical graph of compound 1564



InChIKey: ODZBBRURCPAEIQ-PIXDULNESA-N
SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C=C/Br)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 446727
synonyms found at PubChem are:
Brivudine, 69304-47-8, BVDU, Brivudin, Helpin, (E)-5-(2-Bromovinyl)-2'-deoxyuridine, Bromovinyldeoxyuridine, Zostex, Brivudine [INN], Brivudinum [INN-Latin], Brivudina [INN-Spanish], C11H13BrN2O5, 5-BROMOVINYLDEOXYURIDINE, CCRIS 2831, UNII-2M3055079H, 5-(2-bromovinyl)-2'-deoxyuridine, (E)-5-(2-Bromovinyl)-deoxyuridine, Uridine, 5-(2-bromoethenyl)-2'-deoxy-, (E)-, NSC 633770, trans-5-(2-Bromovinyl)-2'-deoxyuridine, Uridine, 5-[(1E)-2-bromoethenyl]-2'-deoxy-, Brivudine (INN), (E)-5-(2-Bromovinyl)-2-deoxyuridine, NCGC00093656-01, 2M3055079H, Uridine, 5-(2-bromovinyl)-2'-deoxy-, (E)-, Brivudinum, Brivudina, (Z)-5-(2-bromovinyl)-2'-deoxyuridine, 5-[(E)-2-bromovinyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, BVD, uridine, 5-[(1E)-2-bromoethenyl)-2'-deoxy-, 5-BVDU, E-5-(2-bromovinyl)-dUrd, Z-5-(2-bromovinyl)-dUrd, Bridic, Brivox, Zerpex, BrVdUrd, NSC633770, 5-(E)-(2-bromovinyl)-2'-deoxyuridine, BV-dUrd, 5-(2-bromoethenyl)-2'-deoxyuridine, Zostex (TN), D0D3WJ, D0Z9LP, DSSTox_CID_25755, DSSTox_RID_81098, DSSTox_GSID_45755, Lopac0_000175, SCHEMBL99350, CHEMBL31634, SCHEMBL141408, AC1L9K12, (E)-5-(2-Bromovinyl)-dUrd, DTXSID0045755, MolPort-019-879-419, MolPort-023-220-842, ODZBBRURCPAEIQ-PIXDULNESA-N, RP101, ZINC3653378, Tox21_111213, BDBM50366681, MFCD00058585, RP-101, UA-618, e-5-(2-bromovinyl)-2'-deoxyuridine, AKOS015833980, AN-8286, CCG-204270, CS-6292, DB03312, LP00175, RL04648, NCGC00093656-02, AS-35234, HY-13578, CAS-69304-47-8, LS-160809, A-176, EU-0100175, X7276, B 9647, D07249, Z-3305, SR-01000075726, J-700153, SR-01000075726-1, 5-((E)-2-bromovinyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione


ID: 1565

chemical graph of compound 1565



InChIKey: OEBRKCOSUFCWJD-UHFFFAOYSA-N
SMILES: COP(=O)(OC)OC=C(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3039
synonyms found at PubChem are:
dichlorvos, DDVP, 62-73-7, Dichlorophos, Divipan, Vapona, Chlorvinphos, Brevinyl, Canogard, Dichlorphos, Equigard, Krecalvin, Lindanmafu, 2,2-Dichloroethenyl dimethyl phosphate, Bibesol, Equigel, Fecama, Herkal, Herkol, Nerkol, Phosvit, Unifos, Nogos, Nuvan, 2,2-Dichlorovinyl dimethyl phosphate, Dichlorman, Dichlorovos, Estrosel, Szklarniak, Vaponite, Vinylofos, Vinylophos, Winylophos, Atgard, Dedevap, Fekama, Marvex, Mopari, Novotox, Tenac, Task, Atgard C, Atgard V, Nogos G, Vapona Insecticide, Dichloorvo, Astrobot, Cekusan, Dichlofos, Panaplate, Tetravos, Apavap, Benfos, Cypona, DDVP (insecticide), Insectigas D, Nogos 50, Dimethyl 2,2-dichlorovinyl phosphate, Unifos (pesticide), Derribante, Dichlorfos, Diclorvos, Equiguard, Estrosol, Nefrafos, Deriban, Devikol, TAP 9VP, Fly fighter, Mafu strip, No-pest strip, Fly-die, No-pest, Vapora II, Dimethyldichlorovinyl phosphate, Phosphoric acid, 2,2-dichloroethenyl dimethyl ester, Nuvan 7, O,O-Dimethyl dichlorovinyl phosphate, OMS 14, XLP 30, Dichlorovas, Denkavepon, Duravos, Equigand, Uniphos, Verdican, Verdipor, Verdisol, Algard, Dimethyl 2,2-dichloroethenyl phosphate, Unifos 50 EC, NCI-C00113, Nogos 50 EC, Nuvan 100EC, Task tabs, Des (phosphate), BAY-19149, Dimethyl dichlorovinyl phosphate, Bayer 19149, Brevinyl E50, SD-1750, Dichloorvo [Dutch], Brevinyl E-50, Dichlorfos [Polish], DDVF, Phosphoric acid, 2,2-dichlorovinyl dimethyl ester, Caswell No. 328, Delevap, Derriban, Mafu, Nuva, SD 1750, Diclorvos [INN-Spanish], Dichlorvosum [INN-Latin], C4H7Cl2O4P, NSC 6738, NSC-6738, Ethenol, 2,2-dichloro-, dimethyl phosphate, (2,2-Dichloro-vinil)dimetil-fosfato, CCRIS 230, Brevinyl E 50, Dichlorvos [USAN:INN:BAN], UNII-7U370BPS14, (2,2-Dichlor-vinyl)-dimethyl-phosphat, Atgard (TN), Phosphate de dimethyle et de 2,2-dichlorovinyle, UDVF, HSDB 319, Phosphoric acid 2,2-dichloroethenyl dimethyl ester, Vinyl alcohol, 2,2-dichloro-, dimethyl phosphate, BAY-b 4986, O,O-Dimethyl 2,2-dichlorovinyl phosphate, Nuvan 100 EC, Dichlorvos [BSI:ISO], EINECS 200-547-7, Dimethyl-2,2-dichlorovinyl phosphate, ENT 20738, ENT-20738, Phosphoric acid 2,2-dichlorovinyl dimethyl ester, Phosphate, 2-2-dichlorovinyl dimethyl, EPA Pesticide Chemical Code 084001, 2,2-Dichloroethenyl phosphoric acid dimethyl ester, (2,2-Dichloor-vinyl)-dimethyl-fosfaat, BRN 1709141, AI3-20738, CHEMBL167911, O,O-Dimethyl O-2,2-dichlorovinyl phosphate, CHEBI:34690, Dichloroethenyl dimethyl phosphate, O,O-Dimethyl-O-(2,2-dichlor-vinyl)-phosphat, NSC6738, (2,2-Dichloor-vinyl)-dimethyl-fosfaat [Dutch], (2,2-Dichloro-vinil)dimetil-fosfato [Italian], (2,2-Dichlor-vinyl)-dimethyl-phosphat [German], 7U370BPS14, O,O-Dwumetylo-O-dwuchlorowinylofosforan [Polish], 2,2-Dimethyldichlorovinyl phosphate, O-(2,2-Dichlorvinyl)-O,O-dimethylphosphat [German], 2,2-dichloroethenol dimethyl phosphate, O,O-Dimethyl-O-(2,2-dichlor-vinyl)-phosphat [German], OKO, Phosphate de dimethyle et de 2,2-dichlorovinyle [French], NCGC00090997-02, 2,2-Dichlorovinyl-O,O-dimethyl phosphate, DSSTox_CID_449, 2,2-dichlorovinyl alcohol dimethyl phosphate, O-(2,2-Dichlorvinyl)-O,O-dimethylphosphate, 2,2-dichlorovinyl dimethyl phosphoric acid ester, DSSTox_RID_75598, DSSTox_GSID_20449, Dichlorvosum, CAS-62-73-7, Dichlorvos (DDVP), (2,2-Dichloor-vinyl)-dimethyl-fosfaat (Dutch), Dichlorovinphos, Aquaguard, Nuvos, insectigas d, De devap, Prima U, Dichlorvos; DDVP, Dichlorvos (Vapona), Dichlorfos(POLISH), O,O-Dwumetylo-O-dwuchlorowinylofosforan, Spectrum_001779, Dimethyl O,2-phosphate, SpecPlus_000360, Dichlorvos (USAN/INN), o-(2,2-Dichlorvinyl)-O,O-dimethylphosphat, o-(2,O-dimethylphosphat, Spectrum2_001227, Spectrum3_000810, Spectrum4_000650, Spectrum5_001930, AC1L1F1B, 0,2-dichlorovinyl phosphate, SCHEMBL25067, BSPBio_002279, KBioGR_000999, KBioSS_002260, O,2-dichlor-vinyl)-phosphat, MLS002222471, ARONIS23875, BIDD:ER0583, DivK1c_006456, SPBio_001074, WLN: GYGU1OPO&O1&O1, DTXSID5020449, CTK2F3140, KBio1_001400, KBio2_002259, KBio2_004827, KBio2_007395, KBio3_001779, OEBRKCOSUFCWJD-UHFFFAOYSA-, MolPort-003-665-436, OEBRKCOSUFCWJD-UHFFFAOYSA-N, HMS2091C21, dimethyl 2,2-dichlorovinylphosphate, ZINC1853865, ZX-AS004377, Tox21_111052, Tox21_201617, Tox21_300840, BDBM50286926, CCG-39147, LS-271, P5D635, SBB060965, Dichlorvos 100 microg/mL in Acetone, O,O-di methyl dichlorovinyl phosphate, (2, 2-Dichloro-vinil)dimetil-fosfato, (2,2-Dichlorovinyl)-dimethyl-fosfate, AKOS005111045, Tox21_111052_1, FCH1321886, MCULE-3173230917, Dichlorvos 10 microg/mL in Cyclohexane, Ethenol,2-dichloro-, dimethyl phosphate, (2, 2-Dichlor-vinyl)-dimethyl-phosphat, Dichlorvos 100 microg/mL in Cyclohexane, NCGC00090997-01, NCGC00090997-03, NCGC00090997-04, NCGC00090997-05, NCGC00090997-06, NCGC00090997-07, NCGC00090997-08, NCGC00090997-09, NCGC00090997-11, NCGC00254743-01, NCGC00259166-01, AN-23728, CC-26554, CJ-30602, Dimethyl O,O-dichlorovinyl-2,2-phosphate, P598, SMR000777927, SBI-0052506.P003, 2,2-Dichlorovinyl dimethyl phosphate, 8CI, 2,2-Dichlorovinyl-O,O- dimethyl phosphate, DB-054265, Dimethyl O, O-dichlorovinyl-2,2-phosphate, TR-021579, 2,2-bis(chloranyl)ethenyl dimethyl phosphate, FT-0603079, o-(2, 2-Dichlorvinyl)-O,O-dimethylphosphat, O-O-Dimethyl-O(2,2-dichlorovinyl)phosphate, ST51047050, Dichlorvos, PESTANAL(R), analytical standard, Ethenol, 2, 2-dichloro-, dimethyl phosphate, Phosphoric acid,2-dichlorovinyl dimethyl ester, Vinyl alcohol,2-dichloro-, dimethyl phosphate, 0, 0-Dimethyl 0-2,2-dichlorovinyl phosphate, C14430, D03791, 26857-EP2274983A1, 26857-EP2275422A1, 26857-EP2280009A1, 26857-EP2292608A1, 26857-EP2305662A1, 26857-EP2308857A1, 26857-EP2308858A1, 26857-EP2311816A1, 26857-EP2311817A1, 26857-EP2314583A1, 48039-EP2275422A1, 48039-EP2311810A1, AB00053012_02, O,O-Dimethyl-O-(2, 2-dichlor-vinyl)-phosphat, Phosphoric acid,2-dichloroethenyl dimethyl ester, A833962, C-12231, SR-05000001548, DICHLO RVOS [DIMETHYL DICHLORVINYL PHOSPHATE], DICHLORVOS [DIMETHYL DICHLORVINYL PHOSPHATE], I14-2663, O,O-DIMETHYL-O(2,2-DICHLOROVINYL)-PHOSPHATE, Pho sphoric acid 2,2-dichloroethenyl dimethyl ester, SR-05000001548-1, O-(2,2-Dichloroethenyl) O,O-dimethyl phosphate, 9CI, Dichlorvos, United States Pharmacopeia (USP) Reference Standard, InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3, 11095-17-3, 11096-21-2, 11111-31-2, 11126-72-0, 116788-91-1, 12772-40-6, 55819-32-4, 62139-95-1, 62655-59-8, 8023-22-1, 8072-21-7, 8072-39-7, 8076-16-2, 95828-55-0


ID: 1566

chemical graph of compound 1566



InChIKey: OEJNXTAZZBRGDN-UHFFFAOYSA-N
SMILES: C=C1C(C2(C(C(C1(C2(Cl)Cl)Cl)Cl)Cl)Cl)(CCl)CCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5284469
synonyms found at PubChem are:
toxaphene, 8001-35-2, NCGC00091881-01, DSSTox_CID_1368, DSSTox_RID_76114, DSSTox_GSID_21368, CAS-8001-35-2, D0X6OV, AC1NR4I7, GTPL2830, SCHEMBL5933656, CHEMBL1566504, DTXSID90858936, Tox21_111173, Tox21_200912, NCGC00091881-02, NCGC00091881-03, NCGC00258466-01, 1,2,3,4,7,7-hexachloro-6,6-bis(chloromethyl)-5-methylidenebicyclo[2.2.1]heptane, 1,4,5,6,7,7-hexachloro-2,2-bis(chloromethyl)-3-methylidenebicyclo[2.2.1]heptane, 1,4,5,6,7,7-hexachloro-3,3-bis(chloromethyl)-2-methylidenebicyclo[2.2.1]heptane, 1852481-29-8


ID: 1567

chemical graph of compound 1567



InChIKey: OELFLUMRDSZNSF-OFLPRAFFSA-N
SMILES: CC(C)C1CCC(CC1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5311309
synonyms found at PubChem are:
nateglinide, 105816-04-4, Starlix, Fastic, Starsis, senaglinide, Trazec, AY-4166, SDZ-DJN-608, A-4166, DJN-608, DJN 608, Nateglinide [INN], UNII-41X3PWK4O2, AY 4166, CHEMBL783, A 4166, SDZ DJN 608, 41X3PWK4O2, CHEBI:31897, SDZ-DJN 608, AY4166, IPCCPA, YM-026, 105816-06-6, N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine, (-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine, N-{[trans-4-(propan-2-yl)cyclohexyl]carbonyl}-D-phenylalanine, (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid, DSSTox_CID_20687, DSSTox_RID_79543, DSSTox_GSID_40687, N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine, nate-glinide, trans-N-((4-(1-Methylethyl)cyclohexyl)carbonyl)-D-phenylalanine, D-phenylalanine, N-((trans-4-(1-methylethyl)cyclohexyl)carbonyl)-, D-Phenylalanine, N-[[trans-4-(1-methylethyl)cyclohexyl]carbonyl]-, (2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid, SMR000466372, CAS-105816-04-4, N-((4-isopropylcyclohexyl)carbonyl)phenylalanine, glinate, glunate, nateglinida, nateglinidum, natelide, nateglinide, (D-Phe)-isomer, D-Nateglinide, trans-N-{[4-(1-methylethyl)cyclohexyl]carbonyl}-D-phenylalanine, nateglinide, (cis,D-Phe)-isomer, NCGC00095121-01, Nateglinide [USAN:USP:INN:BAN], Starlix (TN), Starsis (TN), Nateglinide, Starlix, Nateglinide (Starlix), AC1NSKEK, Nateglinide cis Impurity, n-{[4-(propan-2-yl)cyclohexyl]carbonyl}phenylalanine, D06PSS, SCHEMBL22088, Novartis brand of nateglinide, MLS000759500, MLS001424043, MLS003915639, MLS006011429, BIDD:GT0257, SCHEMBL303827, 3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid, Nateglinide Related CoMpound C, GTPL6833, SCHEMBL7880361, SCHEMBL9232138, ZINC9689, CHEMBL2114389, D-Phenylalanine, N-((4-(1-methylethyl)cyclohexyl)carbonyl)-, trans-, DTXSID9040687, SCHEMBL13753829, CHEBI:94617, Nateglinide (JP17/USAN/INN), MolPort-003-986-201, OELFLUMRDSZNSF-BRWVUGGUSA-N, HMS2051G20, HMS2089A10, HMS2235O08, HMS3715F12, BCP28400, carboxamido)-3-phenylpropanoic acid, EBD10749, HY-B0422, n-[[trans-4-(1-methylethyl)cyclohexyl]carbonyl]-d-phenylalanine, Tox21_111432, BBL033469, BDBM50344967, MFCD00875706, s2489, STK647123, AKOS005577723, AKOS015841612, AKOS015960899, AKOS027446512, Nateglinide, >=98% (HPLC), solid, Tox21_111432_1, ZINC100015346, ZINC101489663, AC-1690, CCG-100898, CS-2528, DB00731, KS-5143, MCULE-4748076858, NC00148, NCGC00178741-03, NCGC00271534-03, BC204579, CPD000466372, SAM001246721, (R)-2-((1r,4R)-4-isopropylcyclohexane, AB0011153, AB2000594, TL8000218, FT-0631035, N0912, C12508, D01111, K-0514, AB00639979-06, AB00639979-08, AB00639979-09, AB00639979-11, AB00639979_12, 816N044, A-4166;, A801324, A1-02996, Q-201449, N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine, n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine, (trans-4-isopropylcyclohexane-1-carbonyl)-D-phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-D-phenylalanine, Nateglinide, European Pharmacopoeia (EP) Reference Standard, ((1r,4R)-4-isopropylcyclohexane-1-carbonyl)-D-phenylalanine, 2-[(4-Isopropyl-cyclohexanecarbonyl)-amino]-3-phenyl-propionic acid, N-(4alpha-Isopropylcyclohexane-1alpha-yl)carbonyl-D-phenylalanine, Nateglinide, United States Pharmacopeia (USP) Reference Standard, (2R)-2-[(4-isopropylcyclohexanecarbonyl)amino]-3-phenyl-propanoic acid, (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexyl)carbonylamino]propanoic acid, (r)-2-((1r,4r)-4-isopropylcyclohexanecarboxamido)-3-phenylpropanoic acid, (2R)-2-[[oxo-(4-propan-2-ylcyclohexyl)methyl]amino]-3-phenylpropanoic acid, N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine (Nateglinide Impurity), 105746-37-0


ID: 1568

chemical graph of compound 1568



InChIKey: OENYLOITAIRUMV-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC=CC=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 16725071
synonyms found at PubChem are:
5-Hydroxy-7-methoxyisoflavone, 7-Methoxy-5-hydroxyisoflavone, SCHEMBL6142401, CHEMBL3039045, CCG-39771, LMPK12050158, 5-hydroxy-7-methoxy-3-phenyl-4H-chromen-4-one


ID: 1569

chemical graph of compound 1569



InChIKey: OEQHKNWFXHBJIT-UHFFFAOYSA-N
SMILES: CCNC(=O)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 73334
synonyms found at PubChem are:
Amperozide hydrochloride, Amperozide HCl, UNII-8V2171U69N, 75529-73-6, 8V2171U69N, 86725-37-3, NCGC00093556-01, DSSTox_CID_25750, DSSTox_RID_81094, DSSTox_GSID_45750, Hogpax, 4-[4,4-bis(4-Fluorophenyl)butyl]-N-ethyl-1-piperazinecarboxamide hydrochloride, CAS-75529-73-6, Amperozide hydrochloride [MI], Amperozide hydrochloride [WHO-DD], 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide hydrochloride, AC1L2JOD, MLS002153519, SCHEMBL1321270, CHEMBL1257106, DTXSID5045750, CTK8F7757, AOB5283, MolPort-003-983-867, 75558-90-6 (Parent), Tox21_111208, Tox21_500040, AKOS024457273, Tox21_111208_1, API0007812, LP00040, NCGC00015081-04, NCGC00260725-01, AS-16836, SMR001230851, EU-0100040, A 6976, SR-01000076207, SR-01000076207-1, 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxa, 1-Piperazinecarboxamide, 4-(4,4-bis(4-fluorophenyl)butyl)-N-ethyl-, hydrochloride (1:?), 4-(4,4-Bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide hydrochloride, AC1Q1SWE, SCHEMBL17360644


ID: 1570

chemical graph of compound 1570



InChIKey: OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES: CN(C)C(=N)N=C(N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 14219
synonyms found at PubChem are:
Metformin hydrochloride, 1115-70-4, 1,1-Dimethylbiguanide hydrochloride, Metformin HCL, Glucophage, Riomet, Diabefagos, Meguan, Metformin monohydrochloride, Benofomin, Denkaform, Diaberit, Diabesin, Diabetex, Diabetmin, Diaformin, Diaphage, Diformin, Fornidd, Glibomet, Glucofago, Glucoform, Glucoliz, Glucomet, Glucomine, Gluconil, Gluformin, Glupermin, Glyciphage, Glycoran, Glyformin, Meglucon, Mescorit, Metforal, Metolmin, Metomin, Risidon, Siamformet, Thiabet, Walaphage, Biocos, Dextin, Diamin, Geamet, Metbay, N1,N1-Dimethylbiguanide hydrochloride, Dabex, Islotin retard, Diformin Retard, Glucophage-Mite, Apo-Metformin, Novo-Metformin, Glucophage Forte, Glucophage XR, Dimethylbiguanide hydrochloride, Glucophage Retard, DMGG hydrochloride, Glucophage 850, Diabetosan, Fortamet, Metiguanide monohydrochloride, N,N-Dimethylbiguanide hydrochloride, Haurymellin hydrochloride, Metformin (hydrochloride), N,N-dimethylimidodicarbonimidic diamide hydrochloride, LA 6023, HSDB 7080, UNII-786Z46389E, EINECS 214-230-6, Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride, NSC 91485, D 15095, 1,1-Dimethylbiguanide monohydrochloride, AI3-51264, CHEBI:6802, 1,1-Dimethylbiguanide, Hydrochloride, N,N-Dimethylimidodicarbonimidic diamine, 15537-72-1, Glucophage (TN), 786Z46389E, C4H12ClN5, BIGUANIDE, 1,1-DIMETHYL-, HYDROCHLORIDE, DSSTox_CID_17246, DSSTox_RID_79314, DSSTox_GSID_37246, Q-201360, Cidophage, MLS000028493, Metformin HCl ER, NCGC00016564-01, 3-carbamimidoyl-1,1-dimethylguanidine;hydrochloride, SMR000058277, CAS-1115-70-4, D.B.I., Metformin hydrochloride [USAN], Metformin, HCl, DMBG hydrochloride, Prestwick_519, Metformin hydrochloride [USAN:USP:JAN], ACMC-20ap7s, Biguanide, 1,1-dimethyl-, monohydrochloride, Metformin HCl(Glucophage), EC 214-230-6, C4H11N5.HCl, CHEMBL1703, D.B.I, Metformin Hydrochloride,(S), SCHEMBL22977, KSC926E2T, MLS002222221, SPECTRUM1505814, AC1L23D5, Jsp000870, 1-dimethylbiguanide hydrochloride, DTXSID9037246, SCHEMBL10325580, SCHEMBL20140191, CTK8C6229, MolPort-000-771-764, MolPort-039-227-817, OETHQSJEHLVLGH-UHFFFAOYSA-N, HMS1568A09, HMS1922H14, Pharmakon1600-01505814, BCP03594, NSC91485, Metformin hydrochloride (Glucophage), Tox21_110498, BG0401, GP2747, HY-17471A, Metformin hydrochloride (JP17/USP), MFCD00012582, NSC-91485, NSC759262, s1950, N',N'-dimethylbiguanide hydrochloride, AKOS015894259, Tox21_110498_1, AC-2075, AN-8747, API0003318, CCG-208004, CS-1851, KS-1272, LA 6063, MCULE-9784059944, NSC-759262, RP22848, RTR-002281, TRA0069243, KS-000006B5, Biguanide,1-dimethyl-, monohydrochloride, NCGC00016564-06, NCGC00095185-01, NCGC00095185-02, AK163172, BC206669, BP-12830, I506, LS-43900, OR322044, SC-17468, SY001217, 1,1-Dimethylbiguanide hydrochloride, 97%, AB0004717, AB1009370, AX8041182, DB-018697, TL8000340, TR-002281, 1115-70-4 (HCL), FT-0628265, M2009, ST24048701, D00944, J10020, J10377, M-2922, Biguanide, 1,1-dimethyl-, monohydrochloride (8CI), I05-0228, I14-7880, SR-05000001764-2, (E)-2-carbamimidoyl-1,1-dimethylguanidine hydrochloride, F2173-0894, Z2244578658, 3-(diaminomethylene)-1,1-dimethyl-guanidine hydrochloride, 3-(diaminomethylidene)-1,1-dimethylguanidine hydrochloride, Imidodicarbonimidic diamide,N-dimethyl-, monohydrochloride, N-[amino(dimethylamino)methylidene]guanidine hydrochloride, Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base), Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI), Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard, Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard, Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard, Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Metformin hydrochloride, pharmaceutical secondary standard; traceable to USP and PhEur, 144377-16-2, 56258-19-6, amino[(dimethylamino)iminomethyl]carboxamidine, chloride, SBB056982, AKOS024362789, ST50993881, AKOS026749936, 1,1-Dimethylbiguanide hydrochloride, 97% 5g, 177024-EP2275427A1


ID: 1571

chemical graph of compound 1571



InChIKey: OFAYBXSZQCUARK-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C(CO2)CC3=CC(=C(C=C3)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 16667741
synonyms found at PubChem are:
SPECTRUM200848, CHEMBL1356623, SCHEMBL16647710, CCG-214389, NCGC00096027-01, SR-05000002573, SR-05000002573-1, BRD-A92542880-001-01-0


ID: 1572

chemical graph of compound 1572



InChIKey: OFBIFZUFASYYRE-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3373
synonyms found at PubChem are:
flumazenil, 78755-81-4, Anexate, Flumazepil, Romazicon, Lanexat, Mazicon, Ro 15-1788, Flumazenilum, Flumazenilo, Flumazenilum [Latin], Flumazenilo [Spanish], Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate, [11C]flumazenil, Ro 151788, Flumazenil (Ro 15-1788), Ro-15-1788, UNII-40P7XK9392, C15H14FN3O3, CHEMBL407, Ro15-1788, BRN 4763661, MLS000028850, CHEBI:5103, [11C]flumazenil (PET ligand), OFBIFZUFASYYRE-UHFFFAOYSA-N, ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate, Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate, 40P7XK9392, 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester, NCGC00015439-06, SMR000058450, RO-151788, DSSTox_CID_3064, DSSTox_RID_76860, Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate, Ethyl 8-fluoro-5-methyl-5,6-dihydro-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate, DSSTox_GSID_23064, fumazenil, Flumazil, [3H]Ro15-1788, ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate, Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate, CAS-78755-81-4, SR-01000075879, Flumenazil, Flumazenil [USAN:BAN:INN], Roma, Flumazenil [USAN:USP:INN:BAN], Romazicon (TN), 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester, Flumazenil authentic, FlumUP TD, FYP, Tocris-1328, AC1L1FSE, Opera_ID_1516, Lopac-F-6300, Biomol-NT_000285, D02MTS, D0D5GD, UPCMLD-DP137, AC1Q33UE, Lopac0_000506, SCHEMBL79030, Flumazenil (JAN/USP/INN), MLS000759529, MLS001076354, MLS001424108, BIDD:GT0766, BPBio1_001190, GTPL4192, GTPL4367, IMI061, ZINC1464, DTXSID2023064, UPCMLD-DP137:001, BDBM26263, CTK8F9785, KS-00000XSM, AOB5595, MolPort-003-666-855, HMS2051D17, HMS2089B15, HMS2234F06, HMS3261F13, HMS3267P09, HMS3374E10, HMS3393D17, HMS3657K11, Pharmakon1600-01505701, AFC-3002, BCP07573, HY-B0009, Flumazenil, >99% (HPLC), solid, Tox21_110148, Tox21_500506, MFCD00242764, NSC759193, PDSP1_001778, PDSP2_001761, s1332, AKOS015888159, Tox21_110148_1, AC-6846, AN-6313, CCG-100968, CS-0629, DB01205, LP00506, MCULE-2830706565, NC00218, NSC-759193, NCGC00015439-01, NCGC00015439-02, NCGC00015439-03, NCGC00015439-04, NCGC00015439-05, NCGC00015439-07, NCGC00015439-08, NCGC00015439-09, NCGC00015439-11, NCGC00025116-01, NCGC00025116-02, NCGC00025116-03, NCGC00025116-04, NCGC00025116-05, NCGC00261191-01, AJ-08034, AS-13923, CPD000058450, Flumazenil (transdermal patch formulation), K393, LS-77778, SAM001246763, SC-15263, ZB000344, SBI-0050490.P002, AB0014201, AB2000052, Ro-151788000, TL8005362, EU-0100506, F0958, FT-0630863, ST24047162, Ro 15-1788/000, Ro-15-1788/000, C07825, D00697, F 6300, W-5096, AB00572626-12, AB00572626-13, AB00572626_14, AB00572626_15, 755F814, A839484, I01-0379, Q-201122, SR-01000075879-1, SR-01000075879-3, SR-01000075879-7, BRD-K98769987-001-01-3, BRD-K98769987-001-12-0, Flumazenil (transdermal patch formulation), Coeruleus, Flumazepil;Ro 15-1788;Anexate;Lanexat;Mazicon;Roma, Z1551429735, Flumazenil, United States Pharmacopeia (USP) Reference Standard, 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8- fluoro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester, 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester, 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester, 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester, ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0(2),]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate, ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0;{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate, ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate, ethyl 8-fluoranyl-5-methyl-6-oxidanylidene-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate, Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a] [1,4]benzodiazepine-3-carboxylate, ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine-3-carboxylate, Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-3-carboxylate, Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate #


ID: 1573

chemical graph of compound 1573



InChIKey: OFCNXPDARWKPPY-UHFFFAOYSA-N
SMILES: C1=C2C(=NC=NC2=O)NN1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2094
synonyms found at PubChem are:
allopurinol, 315-30-0, 1H-Pyrazolo[3,4-d]pyrimidin-4-ol, Zyloprim, Zyloric, Lopurin, Atisuril, Bleminol, Caplenal, Uripurinol, Embarin, Foligan, Milurit, Progout, Urosin, Anoprolin, Cellidrin, Epidropal, Suspendol, Ailural, Allopur, Allural, Alositol, Bloxanth, Cosuric, Hamarin, Ledopur, Lysuron, Uricemil, Uriprim, Xanturat, Aloral, Anzief, Apurin, Apurol, Geapur, Gotax, Remid, Urbol, Urolit, Urtias, Ketobun-A, Apulonga, Dabrosin, Dabroson, Ketanrift, Miniplanor, Nektrohan, Takanarumin, Urobenyl, Adenock, Allozym, Aluline, Gichtex, Monarch, Riball, Hexanuret, Epuric, 4-Hydroxypyrazolo[3,4-d]pyrimidine, 1H-Pyrazolo[3,4-d]pyrimidin-4(5H)-one, Allo-Puren, 4-HPP, Allopurinol(I), Dura Al, Allopurinolum, Alopurinol, Aloprim, 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine, Urtias 100, 4-Hydroxypyrazolopyrimidine, 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxy-3,4-pyrazolopyrimidine, 4-Hydroxypyrazolo(3,4-d)pyrimidine, Alopurinol [INN-Spanish], Allopurinolum [INN-Latin], 4-Hydroxypyrazolyl(3,4-d)pyrimidine, 4H-Pyrazolo(3,4-d)pyrimidin-4-one, Allohexal, Milurite, Purinol, Sigapurol, Uritas, 4'-Hydroxypyrazolol(3,4-d)pyrimidine, NSC-1390, AL-100, Zyloprim (TN), 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, BW 56-158, Ailurial, B. W. 56-158, Apo-Allopurinol, 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one, BW-56-158, UNII-63CZ7GJN5I, 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-, NSC 1390, 180749-08-0, CCRIS 626, NSC 101655, MLS000069453, 180749-06-8, 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-, CHEBI:40279, 1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one, HSDB 3004, 1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one, EINECS 206-250-9, 2H-Pyrazolo[3,4-d]pyrimidin-4-ol, 73334-58-4, 916980-04-6, 63CZ7GJN5I, BW-56158, SMR000059083, ALLOPURINOL SODIUM, NSC1390, OFCNXPDARWKPPY-UHFFFAOYSA-N, 4H-Pyrazolo[3,4-d]pyrimidin-4-one,1,2-dihydro-, NSC101655, 180749-07-9, 180749-09-1, 184789-03-5, 4-Hydroxypyrazolo-[3,4-d]-pyrimidine, NCGC00015094-02, NCGC00094580-04, 4-Hydroxy-1H-pyrazolo[3,4-d]pyrimidine, BW 56158, 1H-pyrazolo[3,4-d]pyrimidin-4(2H)-one, 1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one, 1,5-Dihydropyrazolo[3,4-d]pyrimidin-4-one, 1H,2H,4H-pyrazolo[3,4-d]pyrimidin-4-one, 1H,4H,7H-pyrazolo[3,4-d]pyrimidin-4-one, DSSTox_CID_2573, A 8003, DSSTox_RID_76636, DSSTox_GSID_22573, pyrazolo[5,4-d]pyrimidin-4-ol, 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,7-dihydro- (9CI), 4H-Pyrazolo[3, 1,5-dihydro-, Jenapurinol, Rimapurinol, Allohexan, Alloprin, Allopurin, Allorin, Allpargin, Capurate, Novopurol, Pureduct, Tipuric, Uribenz, Uridocid, WLN: T56 BMN GN INJ FQ, Xanthomax, Xanturic, Roucol, Zygout, 4-Hydroxypyrazolyl[3,4-d]pyrimidine, Pan Quimica, 4'-Hydroxypyrazolol[3,4-d]pyrimidine, CAS-315-30-0, SR-05000001983, 291279-53-3, Hexanurat, Uricto, ATH008, Quimica, Pan, Lopurin, Zyloprim, Allohexal (TN), Allopurinol [USAN:INN:BAN:JAN], Prestwick_511, Xanthomax-100, Xanthomax-300, Allosig (TN), Progout (TN), Puricos (TN), Zyloric (TN), ALLO, Aluline 100, Aluline 300, Hamarin 100, Hamarin 300, Zyloric-300, Allopurinol [USAN:USP:INN:BAN:JAN], Allopurinol (Zyloprim), PubChem13052, Spectrum_000026, AC1L1CWL, AC1Q6FWV, Opera_ID_1680, Spectrum2_000098, Spectrum3_000289, Spectrum4_000135, Spectrum5_000768, Lopac-A-8003, 1,4-d]pyrimidin-4-one, D04KYY, AC1Q6GP7, cid_2094, SCHEMBL4627, CHEMBL1467, NCIOpen2_001825, Lopac0_000102, BSPBio_001798, KBioGR_000550, KBioSS_000386, KSC171E0R, MLS001148183, US9138393, Allopurinol, US9144538, Allopurinol, DivK1c_000685, SPECTRUM1500108, SPBio_000056, GTPL6795, SCHEMBL1128219, Allopurinol (JP17/USP/INN), Jsp005881, DTXSID4022573, BDBM35440, CTK0H1208, CTK0H1209, CTK5D7801, CTK8H3286, HMS502C07, KBio1_000685, KBio2_000386, KBio2_002954, KBio2_005522, KBio3_001298, MolPort-000-141-383, MolPort-000-870-337, MolPort-003-844-438, MolPort-004-758-643, NINDS_000685, BDBM181133, HMS1920A15, HMS2091G15, HMS2234M09, HMS3259K13, HMS3260E06, HMS3371I11, HMS3651O13, HMS3714L22, Pharmakon1600-01500108, 4-Hydroxypyrazol[3,4-D]pyrimidine, ACT02732, BCP26973, H-Pyrazolo(3,4-d)pyrimidin-4-ol, HY-B0219, STR05189, Tox21_110082, Tox21_200922, Tox21_500102, 2204AH, 4-Hydroxy-pyrazolo[3,4-d]pyrimidin, AC-019, BBL002902, BBL009959, BDBM50016784, BDBM50140241, CCG-38916, CH-782, MFCD00599413, NSC755858, s1630, SBB004202, SC1118, SC2251, STK378584, STK711106, ZINC13298313, AKOS000267490, AKOS000269759, AKOS009031129, AKOS024255717, AKOS030537567, Tox21_110082_1, Allopurinol, xanthine oxidase inhibitor, CCG-204197, CCG-221406, CS-2166, DB00437, LP00102, LS-1180, MCULE-5186178136, NC00492, NSC-101655, NSC-755858, RP01074, RP08415, RTC-063550, TRA0028733, IDI1_000685, NCGC00015094-01, NCGC00015094-03, NCGC00015094-04, NCGC00015094-05, NCGC00015094-06, NCGC00015094-07, NCGC00091134-01, NCGC00091134-02, NCGC00091134-03, NCGC00094580-01, NCGC00094580-02, NCGC00094580-05, NCGC00188948-01, NCGC00258476-01, NCGC00260787-01, AJ-63598, AN-16214, BC202911, BR-49674, CPD000059083, EN000932, KB-65326, SAM002554884, SC-16544, TS-00028, 2h-pyrazolo[3,4-d]pyrimidin-4(5h)-one, 2H-pyrazolo[3,4-d]pyrimidin-4(7H)-one, SBI-0050090.P004, AB0006119, AB0011633, AB0088254, AB1001755, DB-065332, KB-172537, KB-192347, KB-192357, KB-192358, KB-192361, 1H-Pyrazolo[3,4-d]pyrimidin-4-ol (9CI), A0907, EU-0100102, FT-0602537, FT-0685730, FT-0764079, ST45179105, 1,5-dihydropyrazolo[3,4-d]-pyrimidin-4-one, VU0611037-1, BIM-0061756.0001, D00224, L-1944, Q-1018, 32298-EP2272832A1, 32298-EP2281815A1, 32298-EP2292227A2, 32298-EP2292630A1, 32298-EP2295426A1, 32298-EP2295427A1, 32298-EP2301933A1, 32298-EP2305219A1, 32298-EP2305640A2, 32298-EP2311825A1, 32298-EP2311827A1, AB00173448-03, AB00173448-04, AB00173448_05, AB01274719-01, AB01274719_02, 4h-pyrazolo[3,4-d]pyrimidin-4-one,1,7-dihydro-, 4h-pyrazolo[3,4-d]pyrimidin-4-one,2,5-dihydro-, 4h-pyrazolo[3,4-d]pyrimidin-4-one,2,7-dihydro-, AB-323/25048497, Allopurinol (4-Hydroxypyrazolo[3,4-d]pyrimidine), SR-01000075595, 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro-, 4H-pyrazolo[3,4-d]pyrimidin-4-one, 1,7-dihydro-, I03-0052, J-504736, SR-01000075595-1, SR-05000001983-1, SR-05000001983-2, W-106892, 1,7-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE, 1,2-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE, 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one (9CI), F2173-0394, F3329-0375, Z228474686, 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 2,5-dihydro- (9CI), 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 2,7-dihydro- (9CI), Allopurinol, British Pharmacopoeia (BP) Reference Standard, Allopurinol, European Pharmacopoeia (EP) Reference Standard, Allopurinol, United States Pharmacopeia (USP) Reference Standard, 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-, labeled with deuterium, Allopurinol, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10, 184856-42-6, 22767-92-6, 39464-14-7, tautomeric mixture of 1H-pyrazolo[3,4-d]pyrimidin-4-ol and 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one


ID: 1574

chemical graph of compound 1574



InChIKey: OFKNGVGNKBZNOR-QGOVLLJGSA-N
SMILES: CC1(O[C@@H]2C[C@](C[C@H]([C@@H]2O1)O)(C(=O)N)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708787
synonyms found at PubChem are:
KBio2_003432, Spectrum_000384, SpecPlus_000821, Spectrum2_000422, Spectrum3_000261, Spectrum4_001554, Spectrum5_000148, AC1O8FP2, BSPBio_001702, KBioGR_002048, KBioSS_000864, SPECTRUM210837, DivK1c_006917, QUINAMIDE ISOPROPYLIDENE, SPBio_000404, KBio1_001861, KBio2_000864, KBio2_006000, KBio3_001202, CCG-38682, SDCCGMLS-0066514.P001, NCGC00179073-01, SR-05000002476, SR-05000002476-1, (3aR,5R,7R,7aS)-5,7-dihydroxy-2,2-dimethyl-4,6,7,7a-tetrahydro-3aH-1,3-benzodioxole-5-carboxamide


ID: 1575

chemical graph of compound 1575



InChIKey: OFMXGFHWLZPCFL-SVRPQWSVSA-N
SMILES: C[C@H]1C(=O)CC[C@@H]2[C@@]1(CC[C@H]3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C)C)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 91472
synonyms found at PubChem are:
Friedelin, Friedeline, 559-74-0, D:A-Friedooleanan-3-one, Friedelan-3-one, UNII-AK21264UAD, (-)-Friedelin, AK21264UAD, CHEBI:5171, CHEMBL485998, (4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a-octamethylicosahydropicen-3(2H)-one, 3-friedelanone, (4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1H-picen-3-one, SR-05000002227, EINECS 209-205-1, NSC 55141, DA-friedooleanan-3-one, Friedelin, technical grade, AC1Q6P5F, Friedelin, analytical standard, SCHEMBL193053, AC1L3M57, MolPort-003-873-398, ZINC4097720, BDBM50241943, AKOS015897124, API0008506, CCG-208470, AN-45933, CC-28852, W2470, C08626, D:A-Friedooleanan-3-one (VAN) (8CI)(9CI), 559F740, C-22187, I07-0276, SR-05000002227-2, SR-05000002227-3


ID: 1576

chemical graph of compound 1576



InChIKey: OFPMGRPQOZABPO-GZJHNZOKSA-N
SMILES: COC1=CC=CC2=C1[C@@H]3CN(C[C@@H]3CO2)CCCCN4C(=O)C5=C(C6=NC(=CN=C6S5)C7=CC=CC=C7)NC4=O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 172306
synonyms found at PubChem are:
Fiduxosin hydrochloride, Fiduxosin HCl, UNII-UYV23L1N89, UYV23L1N89, 208992-74-9, A-185980.1, Fiduxosin hydrochloride (USAN), Fiduxosin hydrochloride [USAN], MLS002153379, NCGC00162178-02, SMR001230768, AC1L58WW, DSSTox_CID_28939, DSSTox_RID_83205, DSSTox_GSID_49013, SCHEMBL1321348, CHEMBL1256028, DTXSID1049013, CTK8E8988, Tox21_113517, Tox21_500525, CCG-221829, LP00525, NCGC00093918-01, NCGC00261210-01, CAS-208993-54-8, EU-0100525, D04184, F 4303, Fiduxosin hydrochloride, >98% (HPLC), solid, SR-01000076209, J-013707, SR-01000076209-1, (3-[4-((3alphaR,9betaR)-cis-9-methoxy-1,2,3,3a,4,9b-hexahydro-[1]-benzopyrano[3,4-c]pyrrol-2-yl)butyl]-8-phenyl-pyrazino-[2',3':4,5]thi-eno [3,2-d]pyrimidine-2,4(1H,3H)-dione) hydrochloride, (3-[4-((3aR,9bR)-cis-9-methoxy-1,2,3,3a,4,9b-hexahydro-[1]-benzopyrano[3,4-c]Pyrrol-2-yl)butyl]-8-phenyl-pyrazino-[2 inverted exclamation marka,3 inverted exclamation marka:4,5]thieno [3,2-d]pyrimidine-2,4(1H,3H)-dione) hydrochloride, 8-Phenyl-3-(4-((3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy(1)benzopyrano(3,4-c)pyrrol-2(3H)-yl)butyl)pyrazino(2',3':4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione monohydrochloride, Pyrazino(2',3':4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione, 8-phenyl-3-(4-((3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy(1)benzopyran-o(3,4-c)pyrrol-2(3H)-yl)butyl)-,monohydrochloride, Pyrazino(2',3':4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione, 8-phenyl-3-(4-((3aR,9bR)-1,3a,4,9b-tetrahydro-9-methoxy(1)benzopyrano(3,4-c)pyrrol-2(3H)-yl)butyl)-, monohydrochloride


ID: 1577

chemical graph of compound 1577



InChIKey: OFPXSFXSNFPTHF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4614
synonyms found at PubChem are:
oxaprozin, 21256-18-8, Daypro, Alvo, Oxaprozine, 3-(4,5-Diphenyloxazol-2-yl)propanoic acid, 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid, Oxaprozinum, Deflam, Oxaprozina, Voir, Oxaprozine [INN-French], Oxaprozinum [INN-Latin], Oxaprozina [INN-Spanish], Danoprox, Dayrun, WY-21743, WY-21,743, 4,5-Diphenyl-2-oxazolepropionic acid, 4,5-Diphenyl-2-oxazolepropanoic acid, Actirin, Xopane, 2-Oxazolepropanoic acid, 4,5-diphenyl-, WY 21743, NSC310839, Daypro (TN), 3-(4,5-Diphenyl-2-oxazolyl)propenoic acid, beta-(4,5-Diphenyloxazol-2-yl)propionic acid, UNII-MHJ80W9LRB, MHJ80W9LRB, NSC 310839, CHEMBL1071, CHEBI:7822, 3-(diphenyl-1,3-oxazol-2-yl)propanoic acid, C18H15NO3, 2-OXAZOLEPROPIONIC ACID, 4,5-DIPHENYL-, OFPXSFXSNFPTHF-UHFFFAOYSA-N, Oxaprozin [USAN:BAN:INN:JAN], .beta.-(4,5-Diphenyloxazol-2-yl)propionic acid, EINECS 244-296-1, NCI310839, NSC-310839, 4, 5-Diphenyl-2-oxazolepropionic acid, BRN 1083168, 3-(4,5-Diphenyl-2-oxazolyl)propanoic acid, CAS-21256-18-8, O 9637, DSSTox_CID_25118, DSSTox_RID_80684, DSSTox_GSID_45118, Apo-Oxaprozin, Rhoxal-oxaprozin, SMR000058286, SR-01000076053, oxaprosin, Durapro, Duraprost, Oxaprozi, Oxapro, Walix, Oxaprozin, solid, lyl)propenoic acid, Oxaprozin,(S), Duraprox (TN), CSC brand of oxaprozin, TRB brand of oxaprozin, Apotex brand of oxaprozin, Maybridge1_008800, Pfizer brand of oxaprozin, Prestwick0_001060, Prestwick1_001060, Prestwick2_001060, Prestwick3_001060, Spectrum2_001696, Spectrum3_001078, Spectrum4_001231, Lopac-O-9637, D0M9DC, AC1L1IK7, SCHEMBL3286, NCIStruc1_000799, NCIStruc2_000787, BIDD:PXR0149, Lopac0_000944, Oprea1_509470, BSPBio_001020, BSPBio_002696, KBioGR_001722, MLS000759535, MLS001424072, BIDD:GT0438, SPECTRUM1505267, SPBio_001652, SPBio_002940, Rhoxalpharma brand of oxaprozin, AC1Q759J, AC1Q759K, BPBio1_001122, GTPL7252, 3-(4, 5-Diphenyl-2-oxazo, Oxaprozin (JP15/USAN/INN), Oxaprozin (JP17/USAN/INN), DTXSID1045118, CTK7J3117, HMS566H22, HSDB 7586, KBio3_001916, KS-00000ULR, MolPort-000-146-829, HMS1571C22, HMS1922P17, HMS2051L15, HMS2093O08, HMS2098C22, HMS3262N10, HMS3393L15, HMS3652H17, HMS3715C22, Pharmakon1600-01505267, BCP28431, HY-B0808, Tox21_110059, Tox21_500944, 2-Oxazolepropanoic acid,5-diphenyl-, 2-Oxazolepropionic acid,5-diphenyl-, ANW-63377, BDBM50002861, CCG-36508, MFCD00215977, NCGC00014711, NSC758949, s4230, SBB053166, ZINC49643479, 4,5-diphenyloxazole-2-propanoic acid, AKOS000206807, Oxaprozin [USAN:USP:INN:BAN:JAN], Tox21_110059_1, CS-7975, DB00991, KS-5196, LP00944, MCULE-7099031811, NC00214, NSC-758949, NCGC00014711-01, NCGC00014711-02, NCGC00014711-03, NCGC00014711-04, NCGC00014711-05, NCGC00014711-06, NCGC00014711-07, NCGC00014711-08, NCGC00014711-09, NCGC00014711-10, NCGC00014711-11, NCGC00014711-14, NCGC00014711-15, NCGC00094249-01, NCGC00094249-02, NCGC00094249-03, NCGC00094249-04, NCGC00094249-05, NCGC00094249-06, NCGC00094249-07, NCGC00261629-01, AC-26512, AJ-08102, CPD000058286, KB-59357, NCI60_002681, SAM001246770, SC-13926, SBI-0050918.P002, AB0011812, LS-100216, TC-152122, 3-(4,5-Diphenyl-2-oxazolyl)propionic acid, AB00514024, B1804, EU-0100944, FT-0638104, O0377, ST50949623, 3-(4, 5-Diphenyl-2-oxazolyl)propenoic acid, EN300-25629, 3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid, 4.5-Diphenyl-2-oxazolepropanoic acid|||Daypro, C07356, D00463, J10396, K-6109, AB00514024_08, AB00514024_09, 256O188, A815225, I14-8703, J-013955, SR-01000076053-1, SR-01000076053-3, SR-01000076053-7, SR-01000076053-9, 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid #, BRD-K25394294-001-05-7, BRD-K25394294-001-08-1, Z217102860, Oxaprozin, United States Pharmacopeia (USP) Reference Standard


ID: 1578

chemical graph of compound 1578



InChIKey: OFSAJYZMIPNPHE-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CC(=C(C=C1)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 100526
synonyms found at PubChem are:
N-Acetyldopamine, 2494-12-4, N-Acetyldopamine monohydrate, NSC 314644, n-[2-(3,4-dihydroxyphenyl)ethyl]acetamide, CHEMBL137743, BRN 2806306, Acetamide, N-(3,4-dihydroxyphenethyl)-, Acetamide,N-[2-(3,4-dihydroxyphenyl)ethyl]-, Acetamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-, Acetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-, Acetamide, N-(3,4-dihydroxyphenethyl)- (7CI,8CI), N-acetyl-dopamine, 7DP, AC1L2OXA, Lopac-A-8762, Lopac0_000093, SCHEMBL328568, AC1Q5P51, Acetamide,4-dihydroxyphenethyl)-, CTK4F4676, DTXSID70179656, CHEBI:125678, ZINC402700, Acetamide,4-dihydroxyphenyl)ethyl]-, BDBM50035608, N-(3,4-Dihydroxyphenethyl)acetamide, NSC314644, AKOS003589558, N-(3,4-Dihydroxyphenethyl)-Acetamide, CCG-204188, LS-9248, NSC-314644, VZ33103, NCGC00015101-01, NCGC00015101-02, NCGC00015101-03, NCGC00093595-01, NCGC00093595-02, EU-0100093, A 8762, {N-[2-(3,} 4-dihydroxyphenyl)ethyl]-Acetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]ethanimidic acid, SR-01000075692, SR-01000075692-1, BRD-K95847244-001-01-9, N-(2-(3,4-Dihydroxyphenyl)ethyl)acetamide (ACD/Name 4.0)


ID: 1579

chemical graph of compound 1579



InChIKey: OFZCIYFFPZCNJE-UHFFFAOYSA-N
SMILES: CCCC(C)(COC(=O)N)COC(=O)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2576
synonyms found at PubChem are:
carisoprodol, 78-44-4, Carisoprodate, Isomeprobamate, Carisoprodatum, Carisoma, Isobamate, Isoprotane, Isoprothane, Sanoma, Isopropyl meprobamate, SOMA, Atonalyt, Flexartal, Mioartrina, Miolisodal, Mioratrina, Skutamil, Somalgit, Apesan, Arusal, Flexal, Mioril, Nospasm, Relasom, Somanil, Carisoprodolum, Carlsoprol, Brianil, Calenfa, Caprodat, Carisol, Carlsodol, Carlsoma, Carsodal, Diolene, Domarax, Isoprotan, Izoprotan, Mediquil, Mioriodol, Somadril, Stialgin, Caridolin, Carsodol, Chinchen, Fibrosona, Flexagilt, Flexagit, Flexidon, Listaflex, Meprodat, Artifar, Muslax, Neotica, RELA, Scutamil-C, Carisoprodolum [INN-Latin], Tonolyt isopropyl meprobamate, Isopropylmeprobamate, NCI-C56235, SCH 7307, Carisoprodolo [DCIT], Miolisodol, Flexartel, CB 8019, CCRIS 4764, 2-Methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate, HSDB 3021, EINECS 201-118-7, NSC 172124, BRN 1791537, (1-Methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester, Isopropylcarbamic acid, ester with 2-(hydroxymethyl)-2-methylpentyl carbamate, MLS000028401, CHEBI:3419, OFZCIYFFPZCNJE-UHFFFAOYSA-N, C12H24N2O4, Carbamic acid, ester with 2-methyl-2-propyl-1,3-propanediol isopropylcarbamate, Carbamic acid, (1-methylethyl)-, 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester, Carbamic acid, (1-methylethyl)-, 2-[[(aminocarbonyl)oxy]methyl]-2-methylpentyl ester, Carbamic acid, isopropyl-, 2-(hydroxymethyl)-2-methylpentyl ester carbamate (ester), N-Isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate, NCGC00015278-09, SMR000058433, [2-(carbamoyloxymethyl)-2-methylpentyl] N-propan-2-ylcarbamate, (+-)-2-Methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate, DSSTox_CID_4733, 1,3-Propanediol, 2-methyl-2-propyl-, carbamate isopropylcarbamate (ester), Carbamic acid, ester with 2-(hydroxymethyl)-2-methylpentyl isopropylcarbamate, DSSTox_RID_77514, DSSTox_GSID_24733, W-104280, Carisoprodolo, Prazolamine, Soprodol, Carbamic acid, ester with 2-(hydroxymethyl)-2-methylpentylisopropyl carbamate, SR-01000000076, Someprobamate, Carisoprodol [USP:INN:BAN], 2-{[(aminocarbonyl)oxy]methyl}-2-methylpentyl isopropylcarbamate, Carisoprodol [USAN:INN:BAN], CAS-78-44-4, Prestwick_50, Soma (TN), PubChem14803, Spectrum_000102, AC1L1DZK, AC1Q2UIV, Opera_ID_1100, Prestwick0_000423, Prestwick1_000423, Prestwick2_000423, Prestwick3_000423, Spectrum2_001153, Spectrum3_000328, Spectrum4_000265, Spectrum5_000661, D05PLH, CHEMBL1233, Lopac0_000319, SCHEMBL33286, BSPBio_000406, BSPBio_001935, KBioGR_000730, KBioSS_000542, MLS001148409, MLS002454391, DivK1c_000816, SPECTRUM1500162, Carisoprodol (JAN/USP/INN), SPBio_001105, SPBio_002345, BPBio1_000448, GTPL7610, DEA No. 8192, DTXSID8024733, CTK8E7588, HMS502I18, KBio1_000816, KBio2_000542, KBio2_003110, KBio2_005678, KBio3_001155, NINDS_000816, HMS1569E08, HMS1920K03, HMS2091A06, HMS2096E08, HMS2234F13, HMS3259O15, HMS3372H19, HMS3713E08, Pharmakon1600-01500162, HY-B1380, Carisoprodol 1.0 mg/ml in Methanol, Tox21_110122, Tox21_200623, AC-212, CCG-40092, MFCD00057661, NSC172124, NSC756671, AKOS015842914, Tox21_110122_1, WLN: ZVO1X3&1&1OVMY1&1, CS-4819, DB00395, LP00319, LS-1748, MCULE-3695657564, NC00502, NSC-172124, NSC-756671, TRA0083578, IDI1_000816, NCGC00015278-03, NCGC00015278-04, NCGC00015278-05, NCGC00015278-06, NCGC00015278-07, NCGC00015278-08, NCGC00015278-11, NCGC00015278-12, NCGC00015278-14, NCGC00015278-15, NCGC00089734-02, NCGC00089734-03, NCGC00089734-04, NCGC00089734-05, NCGC00089734-06, NCGC00089734-07, NCGC00258177-01, AK167644, AN-16075, BC215420, CPD000058433, SAM002554889, SC-18218, SBI-0050307.P004, AB0073030, AB2000453, TC-063806, AB00051932, EU-0100319, FT-0601536, FT-0656125, ST51037205, Carbamic acid,3-propanediol isopropylcarbamate, C 8759, D00768, EN300-122373, N-Isopropyl-2-methyl-2-propyl-1, dicarbamate, AB00051932_15, 057C661, I06-0388, I14-2709, SR-01000000076-2, SR-01000000076-4, SR-01000000076-6, 1, 2-methyl-2-propyl-, carbamate isopropylcarbamate, Z1565440360, 2-((Carbamoyloxy)methyl)-2-methylpentyl isopropylcarbamate, 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate, N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, N-Isopropyl 2-methyl-2-propyl-1,3-propanediol dicarbamate, N-Isopropyl-2-methyl-2-propyl-1,3-propanediol, dicarbamate, [2-(carbamoyloxymethyl)-2-methyl-pentyl] N-isopropylcarbamate, 2-[(carbamoyloxy)methyl]-2-methylpentyl propan-2-ylcarbamate, Carisoprodol, European Pharmacopoeia (EP) Reference Standard, 1,3-Propanediol, 2-methyl-2-propyl-, carbamate isopropylcarbamate, 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate, 2-methyl-2-({[(propan-2-yl)carbamoyl]oxy}methyl)pentyl carbamate, 2-methyl-2-{[N-(methylethyl)carbamoyloxy]methyl}pentyl aminooate, Carbamic acid 2-isopropylcarbamoyloxymethyl-2-methyl-pentyl ester, Carisoprodol, United States Pharmacopeia (USP) Reference Standard, (RS)-2-{[(aminocarbonyl)oxy]methyl}-2-methylpentyl isopropylcarbamate, Carbamic acid, isopropyl-, 2-(hydroxymethyl)-2-methylpentyl ester carbamate, Isopropylcarbamic acid ester with 2-(hydroxymethyl)-2-methylpentyl carbamate, 1-Methylethyl)carbamic acid 2-[[(aminocarbonyl)oxy]-methyl]-2- methylpentyl ester, 1-Methylethyl)carbamic acid 2-[[(aminocarbonyl)oxy]-methyl]-2-methylpentyl ester, Carbamic acid, isopropyl-, 2-(hydroxymethyl)-2-methylpentyl ester, carbamate, 8053-63-2


ID: 1580

chemical graph of compound 1580



InChIKey: OGBUMNBNEWYMNJ-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCCCOCC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3681
synonyms found at PubChem are:
BATYL ALCOHOL, 544-62-7, Batilol, 1-O-Octadecylglycerol, Stearyl monoglyceride, Batilolum, 3-(octadecyloxy)propane-1,2-diol, 3-(Octadecyloxy)-1,2-propanediol, Glycerine 1-monostearyl ether, 3-octadecoxypropane-1,2-diol, Monooctadecyl ether of glycerol, 3-octadecyloxypropane-1,2-diol, Batylalcohol, Glycerol 1-octadecyl ether, Glyceryl-1-octadecyl ether, 1,2-Propanediol, 3-(octadecyloxy)-, Glycerol monooctadecyl ether, C18:0 Glyceryl 1-ether, Batilol [INN], Batylol, Glycerol octadecyl ether, 1-(Octadecyloxy)-2,3-dihydroxypropane, Batilolum [INN-Latin], (+)-Batylalcohol, NSC 284200, (+)-Batyl alcohol, Batyl alcohol;Batilol, alpha-Octadecylether of glycerol, EINECS 208-874-7, NSC284200, C18:0 Glyceryl 1-ethe, 1-O-Octadecyl-rac-glycerol, BRN 1725677, AI3-18451, CHEBI:34117, OGBUMNBNEWYMNJ-UHFFFAOYSA-N, .alpha.-Octadecylether of glycerol, C21H44O3, NCGC00095748-01, 1, 3-(octadecyloxy)-, DSSTox_CID_8956, DSSTox_RID_82552, DSSTox_GSID_47799, 68990-53-4, Glycerides, C14-22 mono-, WLN: Q1YQ1O18, W-105620, CAS-544-62-7, Bathyl alcohol, Batil alcohol, DL-Batylalcohol, dl-Batyl alcohol, Batyl alcohol, 99%, Spectrum_001658, monoglycerides C18-04, Spectrum2_001609, Spectrum3_000738, Spectrum4_001778, Spectrum5_000395, 4-Oxadocosane-1,2-diol, AC1L1GH5, BSPBio_002296, KBioGR_002296, KBioSS_002138, 4-01-00-02758 (Beilstein Handbook Reference), DivK1c_001035, SCHEMBL117051, SPECTRUM1503983, SPBio_001617, AC1Q2W53, 3-Octadecyloxy-1,2-propanediol, CHEMBL1482516, DTXSID0047799, Glycerol alpha-Monostearyl Ether, rac- 1-O-N-Octadecyl glycerol, CTK1G9769, HMS503O11, KBio1_001035, KBio2_002138, KBio2_004706, KBio2_007274, KBio3_001516, OGBUMNBNEWYMNJ-UHFFFAOYSA-, NSC8716, MolPort-001-783-399, NINDS_001035, KS-000015HL, NSC-8716, 01503944_BATYL, Tox21_111515, ANW-42128, CCG-38893, rac-1-E(R) degrees EIe>>u EOIAN, AKOS015901733, Tox21_111515_1, NSC-284200, SDCCGMLS-0066743.P001, TRA0031734, 1-O-E(R) degrees EIe>>u-rac- EOI, IDI1_001035, NCGC00095748-02, NCGC00095748-04, AN-45798, AS-13696, CC-15804, NCI60_002329, SC-76034, U585, DB-052579, KB-183850, LS-120693, B1202, FT-0632359, C13858, J10123, C-20458, SR-05000002606, I14-1464, SR-05000002606-1, DL-3-E(R) degrees EIeNo>>u-1,2-+/-u paragraph signthorn (1/4), 10438-95-6, InChI=1/C21H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-20-21(23)19-22/h21-23H,2-20H2,1H3


ID: 1581

chemical graph of compound 1581



InChIKey: OGGXGZAMXPVRFZ-UHFFFAOYSA-N
SMILES: C[As](=O)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2513
synonyms found at PubChem are:
cacodylic acid, Dimethylarsinic acid, 75-60-5, Hydroxydimethylarsine oxide, Chexmate, Silvisar, Phytar, Arsan, Erase, DIMETHYLARSENIC ACID, Cacodylate, Arsinic acid, dimethyl-, Silvisar 510, Phytar 560, Ansar 138, Sylvicor, Moncide, Dilic, Rad-e-cate 35, Agent Blue, Acide cacodylique, Alkargen, Phytar 138, Acide dimethylarsinique, Cotton aide HC, Kyselina kakodylova, RCRA waste number U136, Phytar 600, Caswell No. 133, Arsine oxide, hydroxydimethyl-, Ansar, UNII-AJ2HL7EU8K, Acide cacodylique [French], Kyselina kakodylova [Czech], NSC 103115, Arsine oxide, dimethylhydroxy-, Arsinic acid, As,As-dimethyl-, Cacodylate Ion, CCRIS 5893, HSDB 360, Acide dimethylarsenique [French], Acide dimethylarsinique [French], Dimethylarsonic Acid, EINECS 200-883-4, UN1572, AJ2HL7EU8K, RCRA waste no. U136, EPA Pesticide Chemical Code 012501, BRN 1736965, cacodylic-acid, AI3-25369, CHEBI:48765, Bolate, Bolls, UN 1572, Lithium cacodylate, rad-e-cat 25, dimethylarsinos, Lithium, [(dimethyloxoarsenio)oxy]-, Acide dimethylarsenique, C2H7AsO2, Arsecodild, Kakodylsaeure, Silvisad, Ansad, Spectrum_001957, Bolls-eye (Salt/Mix), Phytar 560, DMAd, AC1L1DUK, Me2As(=O)OH, 917-76-0, CAC, DSSTox_CID_508, Spectrum2_001170, Spectrum4_000235, Spectrum5_001683, Hydroxydimethylarsine oxidd, ACMC-1BL1E, Dimethylhydroxyarsine Oxide, Arsine oxide, lithium salt, Arsinic acid, lithium salt, arsinohydroxydimethyl-1-one, bmse000786, bmse000822, Cacodylic acid, >=98%, D06YEV, D09TVP, Dimethylarsinic acid (9CI), DSSTox_RID_75630, NCIOpen2_000362, NCIOpen2_000410, NCIOpen2_001868, DSSTox_GSID_20508, SCHEMBL15351, KBioGR_000929, KBioSS_002511, 4-04-00-03681 (Beilstein Handbook Reference), MLS002207238, ARONIS24203, Arsinic acid,As,As-dimethyl-, Cacodylic acid, >=99.0%, DivK1c_000708, SPECTRUM1503947, SPBio_001159, [As(CH3)2O(OH)], AC1Q296G, AC1Q5A43, CHEMBL1231644, DTXSID7020508, WLN: Q-AS-O&1&1, Cacodylic acid, SAJ first grade, CTK5E1746, HMS502D10, KBio1_000708, KBio2_002503, KBio2_005071, KBio2_007639, OGGXGZAMXPVRFZ-UHFFFAOYSA-, MolPort-003-666-517, NINDS_000708, OGGXGZAMXPVRFZ-UHFFFAOYSA-N, HMS1922O04, Cacodylic acid, analytical standard, NSC71159, Tox21_300767, 6874AF, ANW-36638, CCG-39551, MFCD00002095, NSC-71159, NSC103115, SBB080683, Cacodylic acid [UN1572] [Poison], AKOS005267136, Arsine oxide, hydroxydimethyl- (8CI), Cacodylic acid [UN1572] [Poison], DB02994, LS-1671, NSC-103115, TRA0053425, CAS-75-60-5, IDI1_000708, Dimethylarsinic acid, analytical standard, NCGC00094558-01, NCGC00094558-02, NCGC00094558-03, NCGC00094558-04, NCGC00094558-05, NCGC00094558-06, NCGC00094558-07, NCGC00254671-01, AN-42001, DIMETHYLARSINIC ACID, LITHIUM SALT, NCI60_000084, NCI60_001594, SMR000777886, TR-024299, FT-0623360, C07308, I14-19660, InChI=1/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5), 11126-73-1, 58114-73-1, 8073-10-7


ID: 1582

chemical graph of compound 1582



InChIKey: OGJPXUAPXNRGGI-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4539
synonyms found at PubChem are:
norfloxacin, 70458-96-7, Norfloxacine, Noroxin, Chibroxin, Baccidal, Sebercim, MK-366, Norfloxacinum, Norfloxacino, Barazan, Fulgram, AM-715, Lexinor, NFLX, Zoroxin, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, Norfloxacine [INN-French], Norfloxacinum [INN-Latin], Norfloxacino [INN-Spanish], AM 715, Norflo, MK 0366, UNII-N0F8P22L1P, Noroxin (TN), MK-0366, 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, CCRIS 6302, C16H18FN3O3, CHEMBL9, CHEBI:100246, MK366, 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure, 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, Norfloxacin [USAN:BAN:INN:JAN], EINECS 274-614-4, MK0366, AM-0715, BRN 0567897, MLS000069650, N0F8P22L1P, OGJPXUAPXNRGGI-UHFFFAOYSA-N, NCGC00016916-01, NCGC00016916-09, SMR000058200, CAS-70458-96-7, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, N-8650, 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, DSSTox_CID_17680, DSSTox_RID_79353, DSSTox_GSID_37680, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-piperazinylhydroquinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline-carboxylic acid, SR-01000000222, norphloxacine, Chibroxine, Chibroxol, Gonorcin, Nolicin, Noracin, Noraxin, Norocin, Noroxine, Norxacin, Uroxacin, norfloxacine;, Utinor, Noflo, HSDB 8029, Chibroxin (TN), Norfloxacine,(S), Norflohexal (TN), Insensye (TN), Norfocin (TN), Nufloxib (TN), Prestwick_633, AM0715, Apo-Norflox (TN), MK 366, Utinor (TN), Norfloxacin(Norxacin), Roxin (TN), AM 0715, Norfloxacin [USAN:USP:INN:BAN:JAN], Utin (TN), Norfloxacin (Norxacin), Norfloxacin - Norxacin, Norfloxacin Merck Brand, Spectrum_001017, Opera_ID_1423, Prestwick0_000221, Prestwick1_000221, Prestwick2_000221, Prestwick3_000221, Spectrum2_001017, Spectrum3_000524, Spectrum4_000453, Spectrum5_001154, D0Q2PE, Epitope ID:119068, Merck Brand of Norfloxacin, AC1L1IE1, SCHEMBL3473, Oprea1_375152, BSPBio_000261, BSPBio_002107, KBioGR_000866, KBioSS_001497, MLS006011446, ARONIS24170, BIDD:GT0725, DivK1c_000084, SPECTRUM1500440, SPBio_001173, SPBio_002182, BPBio1_000289, ZINC3742, Norfloxacin (JP15/USP/INN), Norfloxacin (JP17/USP/INN), DTXSID7037680, BCBcMAP01_000218, CTK8B3280, HMS500E06, KBio1_000084, KBio2_001497, KBio2_004065, KBio2_006633, KBio3_001607, BBC/317, MolPort-001-738-625, NINDS_000084, HMS1568N03, HMS1920B16, HMS2090F03, HMS2091J16, HMS2095N03, HMS2235G03, HMS3712N03, Pharmakon1600-01500440, ACT02630, ALBB-015911, BCP27734, EBD35051, HY-B0132, KS-00000GU8, RKL10074, ZX-AN014618, ZX-AS004530, Tox21_110682, Tox21_113441, ANW-42194, BBL005569, BDBM50045000, CCG-40235, GA8833, MFCD00079532, NSC757250, s1509, SBB012542, STK177250, AKOS000417391, Tox21_110682_1, AC-6855, AN-9582, API0003630, BCP9000993, CS-1906, DB01059, KS-5007, MCULE-1115657359, NSC-757250, IDI1_000084, SMP1_000216, NCGC00016916-02, NCGC00016916-03, NCGC00016916-04, NCGC00016916-05, NCGC00016916-06, NCGC00016916-07, NCGC00016916-08, NCGC00016916-11, NCGC00016916-12, NCGC00021725-03, NCGC00021725-04, BC204346, CC-33076, CPD000058200, SAM002264625, SC-16553, ST072202, SBI-0051464.P002, AB0012429, AB1009430, LS-141592, TR-023331, FT-0630800, N0817, C06687, D00210, J10487, Z-0833, AB00052059-18, AB00052059-19, AB00052059_20, AB00052059_21, Norfloxacin, analytical standard, >=98% (TLC), Norfloxacin, VETRANAL(TM), analytical standard, 458N967, C-19611, Norfloxacin, Antibiotic for Culture Media Use Only, I14-0947, SR-01000000222-2, SR-01000000222-3, BRD-K11196887-001-05-5, BRD-K11196887-001-15-4, Z56926638, Norfloxacin, European Pharmacopoeia (EP) Reference Standard, Chibroxin, MK-366, Baccidal, Sebercim, Zoroxin, Norfloxacin, 1-Ethyl-3-carboxy-6-fluoro-7-(piperazinyl-1)-quinolin-4(1H)-one, Norfloxacin, United States Pharmacopeia (USP) Reference Standard, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid, Norfloxacin, Pharmaceutical Secondary Standard; Certified Reference Material, (NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-6-fluoro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid, 1-ethyl-4-oxo-6-fluoro-7-(piperazinyl)-1,4-dihydro-quinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylicAcid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline- carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid #, 1-ethyl-6-fluoro-4-oxo-7-piperazinyl-1,4-dihydro-quinoline-3-carboxylic acid, 1-ethyl-6-fluoro-7-(1-piperazinyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, 1-ethyl-6-fluoro-7-(1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 7-(1-Piperazinyl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Norfloxacin for peak identification, European Pharmacopoeia (EP) Reference Standard, Norfloxacin for system suitability, European Pharmacopoeia (EP) Reference Standard, (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4,4a,8a-tetrahydro-quinoline-3-carboxylic acid (norfloxacin), 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid (Norfloxacin), 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(1-norfloxacin), 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(Norfloxacin), AC1OCG7X, ZB000544, 1-ethyl-6-fluoro-4-oxo-7-piperazin-4-ium-1-ylquinoline-3-carboxylate


ID: 1583

chemical graph of compound 1583



InChIKey: OGMADIBCHLQMIP-UHFFFAOYSA-N
SMILES: C(CS)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 9082
synonyms found at PubChem are:
Cysteamine hydrochloride, 156-57-0, 2-Aminoethanethiol hydrochloride, Cysteamine HCl, Cysteaminium chloride, 2-Mercaptoethylamine hydrochloride, 2-Mercaptoethylamine HCl, Bekaptan, Mercaptamine hydrochloride, Cysteamine (Hydrochloride), Merkamin hydrochloride, 2-Thioethylamine hydrochloride, Mercamine hydrochloride, ETHANETHIOL, 2-AMINO-, HYDROCHLORIDE, Cysteamine chlorohydrate, Mercaptoethylamine hydrochloride, UNII-IF1B771SVB, USAF EE-3, 2-aminoethane-1-thiol hydrochloride, Cysteaminhydrochlorid [German], CCRIS 3926, 2-Mercaptoethylammonium chloride, Cysteamine hydrochloride [USAN], cysteamine, hydrochloride, eta-Mercaptoethylamine hydrochloride, 1-Aminoethane-2-thiol hydrochloride, EINECS 205-858-1, NSC 21116, 1-Amino-2-mercaptoethane hydrochloride, CI 9148, Ethylamine, 2-mercapto-, hydrochloride, IF1B771SVB, AI3-26089, beta-Mercaptoaethylamin chlorhydrat [German], A-889, 2-Aminoethylmercaptan hydrochloride, beta-Mercaptoethylamine hydrochloride, CI-9148, NCGC00094090-01, Ethanethiol, 2-amino-, hydrochloride (1:1), DSSTox_CID_25779, DSSTox_RID_81121, DSSTox_GSID_45779, 16904-32-8, Cysteamine hydrochloride (USAN), 60-23-1 (Parent), CAS-156-57-0, Cysteaminhydrochlorid, cysteamine-hcl, CCRIS 3619, beta-Mercaptoaethylamin chlorhydrat, Cym-H.HCl, cysteamine hydrochoride, 2-aminoethanethiol hcl, 2-aminoethanethiol-hcl, C2H8ClNS, 2-mercaptoethylamine-hcl, C2H7NS.HCl, AC1Q3FCF, Spectrum2_001667, Spectrum3_000992, Spectrum4_001120, Spectrum5_001422, (beta)-MEA Hydrochloride, ACMC-209de3, EC 205-858-1, AC1L1S9Y, SCHEMBL51598, thioethanolamine hydrochloride, KBioGR_001600, KSC491O4D, MLS000028734, SPECTRUM1504226, 2-aminoethanthiol hydrochloride, SPBio_001853, Decarboxy-cysteine hydrochloride, Mercaptamine; MEA hydrochloride, Jsp003081, Thio-ethanol-amine hydrochloride, CHEMBL1256137, DTXSID8045779, 2-amino-ethanethiol hydrochloride, 2-aminoethanethiol, hydrochloride, b-mercaptoethylamine hydrochloride, CTK3J1741, KBio3_001903, 2-mercaptoethanamine hydrochloride, Cysteamine hydrochloride, BioXtra, MolPort-000-145-902, OGMADIBCHLQMIP-UHFFFAOYSA-N, 2-Amino-ethane-thiol hydrochloride, HMS1922H05, Pharmakon1600-01504226, 2-aminoethyl mercaptan hydrochloride, BCP15033, EBD54699, KS-000002LF, 2-Mercapto-ethyl-amine hydrochloride, Hydrochloric acid 2-aminoethanethiol, Tox21_111245, Tox21_500749, AC-301, AN-651, ANW-21625, CCG-39094, MFCD00012904, NSC758692, s4206, AKOS007929948, Tox21_111245_1, CS-2800, LP00749, NE10718, NSC-758692, RTR-006564, 2-Aminoethanethiol hydrochloride (1:1), TRA-0177261, NCGC00015691-06, NCGC00094090-02, NCGC00094090-03, NCGC00094090-04, NCGC00261434-01, AS-12111, BC214793, HY-77591, KB-76368, LS-65766, SMR000059101, Cysteamine hydrochloride, >=97.0% (RT), AB0011291, AB1002034, DB-043323, TR-006564, A0296, Cysteamine hydrochloride, analytical standard, EU-0100749, FT-0611242, ST24040001, AZ0001-0476, Cysteamine hydrochloride, >=98% (titration), C-9520, D03635, M 6500, I14-2638, SR-01000075546-1, Cysteamine hydrochloride, Vetec(TM) reagent grade, 98%, F2191-0299, 116962-86-8, 2-Aminoethanethiol hydrochloride; 2-Aminoethane-1-thiol hydrochloride; Mercaptamine hydrochloride; 2-Mercaptoethylamine hydrochloride; Mercaptoethylammonium chloride, Cysteamine hydrochloride, PharmaGrade, Manufactured under appropriate controls for use as raw material in pharma or biopharmaceutical production., Cysteamine hydrochloride, PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, MCULE-6407472407


ID: 1584

chemical graph of compound 1584



InChIKey: OGMGXKJQIOUTTB-RGMNGODLSA-N
SMILES: C[C@H]1C2=CC(=C(C=C2CCN1)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6419979
synonyms found at PubChem are:
Salsolinol hydrobromide, 38221-21-5, 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-methyl-, hydrobromide, (S)-, (1S)-1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide, Prestwick_563, AC1O4WHC, MLS002153918, CHEMBL553751, 1,2,3,4-TETRAHYDRO-1-METHYL-6,7-ISOQUINOLINEDIOLHYDROBROMIDE, CTK1C5032, DTXSID60191600, HMS1569N18, AKOS030567272, API0008869, CCG-208333, AN-24827, SMR001233265, FT-0639440


ID: 1585

chemical graph of compound 1585



InChIKey: OGQDIIKRQRZXJH-UHFFFAOYSA-N
SMILES: CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 14667
synonyms found at PubChem are:
Concordin, Maximed, Triptyl, Triptil (VAN), Triptil hydrochloride, MK-240, Normethyl EX4442, CHEBI:8598, MK-240 (VAN), EINECS 214-956-3, NSC 169912, 5-(3-Methylaminopropyl)-5H-dibenzo(a,d)cycloheptene hydrochloride, 5H-Dibenzo(a,d)cycloheptene-5-propanamine, N-methyl-, hydrochloride, AC1L24BC, Protriptyline hydrochloride [USAN], LS-60855, 5H-Dibenzo(a,d)cycloheptene-5-propylamine, N-methyl-, hydrochloride, 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-aminium chloride, 5H-DIBENZO(a,d)CYCLOHEPTEN-5-PROPYLAMINE, N-METHYL-, HYDROCHLORIDE, AC1LCWGJ, AKOS026749825, Protriptyline hydrochloride, 1225-55-4, Protriptyline HCl, Protriptyline (hydrochloride), UNII-44665V00O8, MLS000069697, SMR000058503, Vivactil (TN), 44665V00O8, DSSTox_CID_26951, DSSTox_RID_82027, DSSTox_GSID_46951, N-Methyl-5H-dibenzo(a,d)cycloheptene-5-propylamine hydrochloride, NSC169912, SR-01000000208, NCGC00015851-02, CAS-1225-55-4, N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine hydrochloride, 3-(11H-dibenzo[2,1-b:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine;hydrochloride, Protriptyline hydrochloride [USAN:USP], Opera_ID_812, MLS001074210, MLS002222305, SCHEMBL119341, 438-60-8 (Parent), CHEMBL1200332, DTXSID8046951, MolPort-003-959-364, OGQDIIKRQRZXJH-UHFFFAOYSA-N, Protriptyline hydrochloride (USP), REGID_for_CID_6603149, HMS1570J22, Pharmakon1600-01505984, HY-B0949, Tox21_110244, Tox21_500974, MFCD00072057, NSC759297, AKOS024374984, Tox21_110244_1, API0008571, CCG-213590, LP00974, MCULE-3161866738, NSC-169912, NSC-759297, WLN: L C676 BHJ B3M1 &GH, 5H-Dibenzo[a, N-methyl-, hydrochloride, NCGC00015851-10, NCGC00094274-01, NCGC00094274-02, NCGC00261659-01, EU-0100974, ST51015111, D00484, P 8813, 225P554, J-004824, Protriptyline hydrochloride, >=99% (TLC), powder, SR-01000000208-2, SR-01000000208-7, d)cyclohepten-5-propylamine,n-methyl-5h-dibenzo(hydrochloride, n-methyl-5h-dibenzo(a,d)cycloheptene-5-propylaminehydrochloride, 5-(3-methylaminopropyl)-5h-dibenzo(a,d)cycloheptenehydrochloride, 5-[3-(Methylamino)propyl]-5H-dibenzo[a,d]cycloheptene hydrochloride, Protriptyline Hydrochloride 1.0 mg/ml in Methanol (as free base), (3-(5-hydrodibenzo[b,f][7]annulen-5-yl)propyl)methylamine, chloride, 5H-Dibenzo(a,d)cycloheptene-5-propylamine, N-methyl-, hydrochloride (8CI), Protriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard, Protriptyline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material


ID: 1586

chemical graph of compound 1586



InChIKey: OHAPBZNQODVZQM-UHFFFAOYSA-M
SMILES: C1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 10634386


ID: 1587

chemical graph of compound 1587



InChIKey: OHHDIOKRWWOXMT-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 62935
synonyms found at PubChem are:
Trazodone hydrochloride, 25332-39-2, Trazodone Hcl, Desyrel, Bimaran, Molipaxin, Devidon, Pragmazone, Thombran, Tombran, Tritico, Triticum, Azona, Apo-Trazodone, Trazodone (hydrochloride), UNII-6E8ZO8LRNM, Oleptro, EINECS 246-855-5, KB-831, 6E8ZO8LRNM, NSC 292811, AF 1161, AF-1161, MLS000069698, CHEBI:9655, Trazodone hydrochloride (Desyrel), 2-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2H)-one monohydrochloride, HSDB 7048, SMR000058520, Desyrel (TN), DSSTox_CID_24626, DSSTox_RID_80361, DSSTox_GSID_44626, 1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride, 19666-36-5, 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride, 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride, C19H23Cl2N5O, 2-(3-(4-(3-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2H)-one HCl, 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-,hydrochloride (1:1), 2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo(4,3-a)pyridine-3(2H)-one hydrochloride, s-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride, SR-01000000190, NCGC00016035-02, CAS-25332-39-2, Trazodone, HCl, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one hydrochloride, 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one;hydrochloride, 2-[3-[4-(m-Chlorophenyl)-1-piperazinyl]propyl]-s-triazolo[4,3-a]pyridin-3(2H)-one monohydrochloride, Prestwick_478, EINECS 243-216-2, Trazodone hydrochloride [USAN:JAN], PubChem15888, Trazodone hydrochloride [USAN:USP:JAN], Opera_ID_850, AC1Q3BFE, C19H22ClN5O.HCl, AC1L1Y2P, SCHEMBL61754, MLS000758230, MLS001148260, MLS001424009, SPECTRUM1503121, Jsp005028, CHEMBL1200798, DTXSID8044626, CTK4F5497, KS-00000ZWU, MolPort-001-684-664, HMS1568L06, HMS1922G09, Pharmakon1600-01503121, Trazodone hydrochloride (JAN/USP), BCP04922, HY-B0478, Tox21_110286, Tox21_302685, Tox21_501159, CCG-40299, CT0209, MFCD00079603, NSC292811, NSC758393, AKOS015897762, Tox21_110286_1, AC-6779, AN-9680, CS-2592, KS-5100, LP01159, MCULE-3098459714, NC00046, NSC-292811, NSC-758393, VA11904, NCGC00016035-13, NCGC00094420-01, NCGC00094420-02, NCGC00094420-03, NCGC00094420-04, NCGC00256807-01, NCGC00261844-01, 2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2H)-one hydrochloride, 4CA-1276, BC215367, CPD000058520, SAM001247045, SC-16187, AB2000676, LS-156736, ST2407780, EU-0101159, FT-0659024, S2582, ST51015149, D00820, J10153, K-6661, T 6154, Trazodone hydrochloride, >=99% (HPLC), powder, 332T392, A813950, A817789, I13-027, 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-, J-015941, SR-01000000190-2, SR-01000000190-8, WLN: T56 ANVNNJ C3- AT6N DNTJ DR CG &GH, 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, Z1550675462, Trazodone Hydrochloride 1.0 mg/ml in Methanol (as free base), Trazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard, S-Triazolo[4, 2-[3-[4-(m-chlorophenyl)-1-piperazinyl]propyl]-, monohydrochloride, S-Trizolo[4, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, hydrochloride, 1,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, monohydrochloride, 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, 2-{3-[4-(3-chlorophenyl)piperazinyl]propyl}-4-hydro-1,2,4-triazolino[4,3-a]pyr idin-3-one, chloride, s-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-,monohydrochloride, AC1LCWES, AKOS026750159, 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one; hydron; chloride


ID: 1588

chemical graph of compound 1588



InChIKey: OHLQBKZXSJYBMK-UHFFFAOYSA-N
SMILES: C#CCCCCCCCCCCCC(CC(CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3015189
synonyms found at PubChem are:
AVOCADYNE, heptadec-16-yne-1,2,4-triol, 16-Heptadecyne-1,2,4-triol, 24607-05-4, KBio2_006118, Heptadecane-16-yne-1,2,4-triol, Spectrum_000502, AC1MI0RL, Spectrum2_000528, Spectrum3_001136, Spectrum4_001983, Spectrum5_000238, Spectrum5_001722, BSPBio_002631, KBioGR_002512, KBioSS_000982, SPECTRUM1505234, SPBio_000515, CHEMBL443127, SCHEMBL1970908, CTK1A2188, KBio2_000982, KBio2_003550, KBio3_002131, MolPort-003-665-935, HMS1923M03, 1,2,4-trihydroxyheptadec-16-yne, CCG-38718, LMFA05000643, MCULE-6580235411, NCGC00095269-01, NCGC00095269-02, NCGC00095269-03, SR-05000002544, SR-05000002544-1


ID: 1589

chemical graph of compound 1589



InChIKey: OHXPGWPVLFPUSM-KLRNGDHRSA-N
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(C(=O)C[C@H]3[C@H]2C(=O)C[C@H]4[C@@]3(CCC(=O)C4)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6674
synonyms found at PubChem are:
dehydrocholic acid, Decholin, 81-23-2, Dehystolin, Felacrinos, Sanocholen, Oxycholin, Ketocholanic acid, Bilidren, Bilostat, Cholagon, Cholimed, Chologon, Dehychol, Didrocolo, Drenobyl, Novocolin, Procholon, Acolen, Dehycon, Didocol, Dilabil, Erebile, Hykolex, Deidrocolico Vita, dehydrocholate, Biochol, Dehycol, Ketochol, Khologon, Triketocholanic acid, Doxycholpotassium, Cholan DH, Cholic acid, dehydro-, Dee-Co, 3,7,12-Trioxocholanic acid, Dehydrocholsaeure, 3,7,12-Triketocholanic acid, 3,7,12-Trioxo-5beta-cholanic acid, Acide dehydrocholique, 3,7,12-Trioxo-5beta-cholan-24-oic acid, Cholepatin, Hydrochol, 3,7,12-Triketo-5beta-cholanoic acid, Dehydrocholsaeure [German], Acido deidrocolico [DCIT], Acido dehidrocolico [Spanish], Acide dehydrocholique [French], Acidum dehydrocholicum [Latin], UNII-NH5000009I, Acido dehidrocolico [INN-Spanish], Acide dehydrocholique [INN-French], Acidum dehydrocholicum [INN-Latin], NSC 8796, EINECS 201-335-7, BRN 3226734, 5beta-Cholanic acid, 3,7,12-trioxo-, MLS000069501, (5beta)-3,7,12-trioxocholan-24-oic acid, 3,7,12-Trioxo-5-beta-cholan-24-oic acid, CHEBI:31459, OHXPGWPVLFPUSM-KLRNGDHRSA-N, C24H34O5, Cholan-24-oic acid, 3,7,12-trioxo-, (5beta)-, 5beta-Cholanic acid-3,5,12-trione, Cholan-24-oic acid, 3,7,12-trioxo-, (5-beta)-, NH5000009I, (4R)-4-[(5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7,12-trioxo-1,2,4,5,6,8,9,11,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid, SMR000058603, DSSTox_CID_2888, 5-beta-Cholan-24-oic acid, 3,7,12-trioxo-, DSSTox_RID_76775, Cholan-24-oic acid, 3,7,12-trioxo-, (5b)-, DSSTox_GSID_22888, 3,7,12-triketo-5b-cholanic acid, Cholan-24-oic acid, 3,7,12-trioxo-, (5.beta.)-, Acido deidrocolico, Acido dehidrocolico, 4-((1S,2S,7S,11S,10R,14R,15R)-2,15-dimethyl-5,9,16-trioxotetracyclo[8.7.0.0<2, 7>.0<11,15>]heptadec-14-yl)pentanoic acid, Acidum dehydrocholicum, dehydrocholic, Atrocholin, Trioxocholate, Decholine, Dilahil, dehydocholic acid, NCGC00095777-01, Decholin (TN), Dehydrocholic acid [INN:BAN:JAN], Prestwick_498, Dehydrocholic acid [USP:INN:BAN:JAN], 94107-86-5, Opera_ID_1391, Prestwick3_000123, 3,12-Trioxocholanic acid, 3,12-Triketocholanic acid, SCHEMBL26391, BSPBio_000166, 4-10-00-03478 (Beilstein Handbook Reference), MLS001076501, MLS001424181, AC1L1N21, BPBio1_000184, CHEMBL514446, DTXSID2022888, CTK5H5009, BIC0609, NSC8796, MolPort-003-929-721, 3,7,12-trioxo-5-cholanic acid, 7786-84-7 (magnesium salt), HMS2052A11, HMS2095I08, HMS2235J07, HMS3712I08, 145-41-5 (hydrochloride salt), 94107-86-5 (lithium salt), HY-B1393, NSC-8796, ZINC3860869, 3,7,12-Trioxo-24-cholanic acid, Purified dehydrocholic acid (JP17), Tox21_111519, LMST04010106, MFCD00066410, PDSP2_000076, s4562, 3,12-Trioxo-5.beta.-cholanic acid, Dehydrocholic acid (JP17/USP/INN), Dehydrocholic acid, >=99.0% (T), 3,12-Triketo-5.beta.-cholanic acid, AKOS024284359, Tox21_111519_1, 3,12-Triketo-5.beta.-cholanoic acid, 5.beta.-Cholanic acid,7,12-trioxo-, API0002239, CCG-101103, CS-4902, DB11622, NC00353, 3,7,12-Trioxo-5.beta.-cholanic acid, 3,7,12-Trioxocholan-24-oic acid #, 3,7,12-Triketo-5.beta.-cholanic acid, NCGC00024025-03, NCGC00024025-05, 3,7,12-Triketo-5.beta.-cholanoic acid, AJ-46071, AK-78702, AN-24040, CPD000058603, LS-53056, SAM001246857, ST075165, 5.beta.-Cholanic acid, 3,7,12-trioxo-, 3,12-Trioxo-5.beta.-cholan-24-oic acid, AX8083115, KB-277238, 5.beta.-Cholan-24-oic acid,7,12-trioxo-, D0042, ST24046425, 3,7,12-Trioxo-5.beta.-cholan-24-oic acid, 5beta-Cholan-24-oic acid, 3,7,12-trioxo-, C13154, D01693, 3,7,12-Tri-keto-5.beta.-Cholan-24-oic acid, 5.beta.-Cholan-24-oic acid, 3,7,12-trioxo-, Cholan-24-oic acid,7,12-trioxo-, (5.beta.)-, SR-01000003022, SR-01000003022-3, W-104212, 5beta-Cholan-24-oic acid, 3,7,12-trioxo- (8CI), BRD-K90976994-001-02-1, Dehydrocholic acid, United States Pharmacopeia (USP) Reference Standard, (R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7,12-trioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid


ID: 1590

chemical graph of compound 1590



InChIKey: OIGNJSKKLXVSLS-VWUMJDOOSA-N
SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5755
synonyms found at PubChem are:
prednisolone, 50-24-8, Metacortandralone, Hydroretrocortine, Predonine, Deltacortril, Meticortelone, Deltahydrocortisone, Prenolone, Hydroretrocortin, Delta-Cortef, PRDL, Deltacortenol, Hydrodeltalone, Hydrodeltisone, Codelcortone, Cortalone, Cotogesic, Decaprednil, Delcortol, Deltisilone, Dicortol, Donisolone, Dydeltrone, Erbacort, Erbasona, Estilsona, Fernisolone, Hydeltra, Hydeltrone, Lentosone, Paracortol, Paracotol, Precortancyl, Precortilon, Precortisyl, Prednelan, Prednicen, Predniliderm, Predonin, Rolisone, Scherisolon, Sterolone, Cordrol, Prednis, Prelone, Steran, Sterane, Ulacort, Fernisolone P, Hostacortin H, Ultracorten H, Ultracortene-H, Delta-stab, Predne-Dome, Decortin H, CO-Hydeltra, Eazolin D, Meti-Derm, Di-adreson F, Delta F, Derpo PD, 1-Dehydrohydrocortisone, Solone, Delta-Ef-Cortelan, Predniretard, Prednisolona, Prednisolonum, delta(1)-Hydrocortisone, Pediapred, Orapred, delta(1)-Dehydrocortisol, Fernisolone-P, Dexa-Cortidelt hostacortin H, 1,2-Dehydrohydrocortisone, Cotolone, Prednisolonum [INN-Latin], Prednisolona [INN-Spanish], delta(1)-Cortisol, Ultracortene-hydrogen, 1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione, Deltasolone, Klismacort, Panafcortelone, delta(sup 1)-Cortisol, UNII-9PHQ9Y1OLM, (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, 1-Dehydrocortisol, delta(sup 1)-Hydrocortisone, 1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol, 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione, CCRIS 980, delta(sup 1)-Dehydrocortisol, K 1557, 3,20-Dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene, Delta(1)-dehydrohydrocortisone, Prednisolone [INN:BAN:JAN], .DELTA.1-Cortisol, HSDB 3385, delta(sup 1)-Dehydrohydrocortisone, NSC 9120, EINECS 200-021-7, .DELTA.1-Hydrocortisone, 9PHQ9Y1OLM, .DELTA.1-Dehydrocortisol, CHEMBL131, Predisolone Sodium Phosphate, BRN 1354103, CHEBI:8378, .DELTA.1-Dehydrohydrocortisone, Poly-Pred, .delta.-Cortef, Neo-Delta-Cortef, OIGNJSKKLXVSLS-VWUMJDOOSA-N, .delta.-Stab, Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one, 11-beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione, component of Ataraxoid, 1,4-Pregnadien-11-beta,17-alpha,21-triol-3,20-dione, 1,4-Pregnadiene-11-beta,17-alpha,21-triol-3,20-dione, 1,4-Pregnadiene-3,20-dione-11-beta,17-alpha,21-triol, Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, DSSTox_CID_1184, component of K-Predne-Dome, DSSTox_RID_75996, DSSTox_GSID_21184, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, Predate, Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11b)-, Bubbli-Pred, Di-Adreson-F, SMR000718761, MLS002638110, Pregna-1,20-dione, 11.beta.,17,21-trihydroxy-, Precortalon, Supercortisol, Flamasone, Nanocort, Preflam, Pregna-1,20-dione, 11,17,21-trihydroxy-, (11.beta.)-, Ultracortene H, Ophtho-Tate, Predate Tba, Predcor-Tba, Predni-Dome, Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-, Ultra Pred, Lite Pred, Predair A, Key-Pred, Ocu-Pred, Ocu-Pred Forte, Ak-Pred, Articulose-50, CAS-50-24-8, I-Pred, NCGC00094764-01, delta-hydrocortisone, Predate-50, Predcor-25, Predcor-50, Prestwick_404, delta-dehydrocortisol, Deltacortril Enteric, DELTA.1-Cortisol, Delta-Cortef (TN), Nor-Pred T.B.A., T-Pred (Salt/Mix), Prednisolone (anhydrous), Prednisolone, >=99%, Prestwick0_000274, Prestwick1_000274, Prestwick2_000274, Prestwick3_000274, delta-dehydrohydrocortisone, D0D1SG, EC 200-021-7, AC1L1L2E, SCHEMBL3233, K-Predne-Dome (Salt/Mix), 11beta,17alpha,21-Trihydroxypregna-1,4-diene-3,20-dione, .DELTA.(sup 1)-Cortisol, BSPBio_000148, 4-08-00-03467 (Beilstein Handbook Reference), MLS001304083, MLS002154250, MLS002207037, MLS002548883, SPBio_002367, BPBio1_000164, GTPL2866, DTXSID9021184, .DELTA.(sup 1)-Hydrocortisone, BDBM19190, CTK8A1104, Prednisolone (JP17/USP/INN), NSC9120, NSC9900, .DELTA.(sup 1)-Dehydrocortisol, MolPort-002-507-147, OIGNJSKKLXVSLS-UHFFFAOYSA-N, HMS1568H10, HMS2090J05, HMS2095H10, HMS2230P10, HMS3259E09, HMS3712H10, BCP09053, NSC-9120, NSC-9900, ZINC3833821, Tox21_111327, Tox21_201673, Tox21_302987, CP0099, LMST02030179, MFCD00003649, s1737, .DELTA.(sup 1)-Dehydrohydrocortisone, AKOS015894935, Tox21_111327_1, AC-1773, CCG-220274, CS-2249, DB00860, LS-7669, NC00473, RL03844, NCGC00179649-01, NCGC00179649-02, NCGC00179649-03, NCGC00179649-04, NCGC00179649-06, NCGC00256577-01, NCGC00259222-01, 11,17-Dihydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one, AJ-45803, AN-14635, AS-13665, BC678521, CJ-10795, HY-17463, P0637, ST24049031, EN300-53017, 5948-EP0930075A1, 5948-EP2272832A1, 5948-EP2277565A2, 5948-EP2277566A2, 5948-EP2277567A1, 5948-EP2277568A2, 5948-EP2277569A2, 5948-EP2277570A2, 5948-EP2277861A1, 5948-EP2277865A1, 5948-EP2281815A1, 5948-EP2292280A1, 5948-EP2295426A1, 5948-EP2295427A1, 5948-EP2298778A1, 5948-EP2301933A1, 5948-EP2305219A1, 5948-EP2305248A1, 5948-EP2305663A1, 5948-EP2308562A2, 5948-EP2308880A1, 5948-EP2311827A1, 5948-EP2314585A1, 5948-EP2314590A1, 5948-EP2316832A1, 5948-EP2316833A1, 5948-EP2371811A2, C07369, D00472, J10078, Prednisolone, VETRANAL(TM), analytical standard, 003P649, 1,4-Pregnadiene-11b,17a,21-triol-3,20-dione, SR-01000837502, Q-201616, SR-01000837502-2, 11b,17,21-Trihydroxypregna-1,4-diene-3,20-dione, BRD-K98039984-001-03-0, BRD-K98039984-001-06-3, 11beta,17,21-trihydroxy-1,4-pregnadiene-3,20-dione, Z1245633279, 11-.beta.,17,21-Trihydroxypregna-1,4-diene-3,20-dione, 11beta,17alpha,21-Trihydroxy-1,4-pregnadiene-3,20-dione, 1,4-Pregnadien-11-.beta.,17-.alpha.,21-triol-3,20-dione, 1,4-Pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione, 1,4-Pregnadiene-3,20-dione-11-.beta.,17-.alpha.,21-triol, 11beta, 17alpha, 21-Trihydroxypregna-1,4-diene-3,20-dione, Prednisolone, European Pharmacopoeia (EP) Reference Standard, Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, Pregna-1,4-diene-3,20-dione, 11.beta.,17,21-trihydroxy-, 11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, (11.beta.)-, 11-.beta.,17-.alpha.,21-Trihydroxy-1,4-pregnadiene-3,20-dione, 11-.beta.,17-.alpha.,21-Trihydroxypregna-1,4-diene-3,20-dione, 11.beta.,17.alpha.,21-Trihydroxypregna-1,4-diene-3,20-dione, Prednisolone (injectable liposome formulation, rheumatoid arthritis), Prednisolone, United States Pharmacopeia (USP) Reference Standard, Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy- (8CI), Prednisolone (injectable liposome formulation, rheumatoid arthritis), Enceladus, Prednisolone (injectable liposome formulation, rheumatoid arthritis), Galapagos, Prednisolone for peak identification, European Pharmacopoeia (EP) Reference Standard, Prednisolone for system suitability, European Pharmacopoeia (EP) Reference Standard, Prednisolone, Pharmaceutical Secondary Standard; Certified Reference Material, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-3,6-dien-5-one, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-5-one, 58201-11-9, 8056-11-9, Prednisolone solution, 100 mug/mL in acetonitrile, ampule of 1 mL, certified reference material


ID: 1591

chemical graph of compound 1591



InChIKey: OIPILFWXSMYKGL-UHFFFAOYSA-N
SMILES: CC(=O)OCC[N+](C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 187
synonyms found at PubChem are:
acetylcholine, Choline acetate, O-Acetylcholine, Acetyl choline ion, Acetylcholinum, 51-84-3, (2-Acetoxyethyl)trimethylammonium, Acetyl choline cation, Choline acetate (ester), Ach, 2-(Acetyloxy)-N,N,N-trimethylethanaminium, Azetylcholin, ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, UNII-N9YNS0M02X, [3H]acetylcholine, BRN 1764436, CHEBI:15355, Bromoacetylcholine, EINECS 200-128-9, CHEMBL667, N9YNS0M02X, 2-acetyloxyethyl(trimethyl)azanium, [2-(acetyloxy)ethyl]trimethylazanium, Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl- (9CI), 2-acetyloxyethyl-trimethylazanium, NCGC00018123-05, C7H16NO2, 2rin, 3rqw, Acetylcholine cation, (14C)Acetylcholine, (14C)-Acetylcholine, Spectrum_000022, 2ha4, 2xz5, Spectrum2_001258, Spectrum3_000286, Spectrum4_000136, Spectrum5_000762, D04GON, D0Q9HF, Epitope ID:176773, ACETYLCH0LINE IODIDE, cid_6060, SCHEMBL3216, 60-31-1 (chloride), 66-23-9 (bromide), BSPBio_001792, GTPL294, KBioGR_000552, KBioSS_000382, 4-04-00-01446 (Beilstein Handbook Reference), DivK1c_000686, 927-86-6 (perchlorate), SPBio_001196, Acetylcholinium: acetyl-Choline, AC1L18O9, GTPL8593, DTXSID8075334, 2260-50-6 (iodide), BDBM10759, CTK4B9009, KBio1_000686, KBio2_000382, KBio2_002950, KBio2_005518, KBio3_001292, NINDS_000686, OIPILFWXSMYKGL-UHFFFAOYSA-N, HMS2089A14, ZINC3079336, DB03128, MCULE-7765616505, 2-acetyloxy-N,N,N-trimethylethanaminium, IDI1_000686, 2-acetoxyethyl(trimethyl)ammonium;bromide, NCGC00018123-01, NCGC00018123-02, NCGC00018123-03, NCGC00018123-04, NCGC00021161-03, NCGC00021161-04, NCGC00163215-01, AJ-44413, LS-53168, SBI-0051271.P003, 2-acetoxyethyl(trimethyl)ammonium;perchlorate, FT-0689161, ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl, 4774-EP2269989A1, 4774-EP2272537A2, 4774-EP2275420A1, 4774-EP2280006A1, 4774-EP2280010A2, 4774-EP2281813A1, 4774-EP2281824A1, 4774-EP2284171A1, 4774-EP2287163A1, 4774-EP2295437A1, 4774-EP2298734A2, 4774-EP2298758A1, 4774-EP2298759A1, 4774-EP2298772A1, 4774-EP2298775A1, 4774-EP2305644A1, 4774-EP2305664A1, 4774-EP2305675A1, 4774-EP2305678A1, 4774-EP2308839A1, 4774-EP2308873A1, 4774-EP2308875A1, 4774-EP2308876A1, 4774-EP2311823A1, 4774-EP2311828A1, 4774-EP2311831A1, 4774-EP2314571A2, 4774-EP2316836A1, C01996, 21686-EP2272972A1, 21686-EP2272973A1, 21686-EP2277872A1, 21686-EP2314571A2, 21686-EP2371803A1, 21686-EP2377843A1, AB00053790-25, AB00053790_26, AB00053790_27, L000783, 2-(Acetyloxy)-N,N,N-trimethylethanaminium labeled with carbon-14, InChI=1/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+, Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, labeled with carbon-14 (9CI), 14047-05-3


ID: 1592

chemical graph of compound 1592



InChIKey: OIRFJRBSRORBCM-UHFFFAOYSA-N
SMILES: CCC(CC1=C(C(=C(C=C1I)I)N)I)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3735
synonyms found at PubChem are:
IOPANOIC ACID, Iodopanoic acid, 96-83-3, Telepaque, Cholevid, Iopagnost, Polognost, Iopanoicum, Jopanoic acid, Bilijodon, Choladine, Cistobil, Colepax, Copanoic, Jopagnost, iopanic acid, 2-(3-Amino-2,4,6-triiodobenzyl)butyric acid, Teletrast, Iodopanic acid, 2-(3-Amino-2,4,6-triiodobenzyl)butanoic acid, Acidum iopanoicum, NSC 41706, Acide iopanoique [French], Acide iopanoique [INN-French], Acido iopanoico [INN-Spanish], Acidum iopanoicum [INN-Latin], Acido iopanoico [Latin,Spanish], HSDB 3345, WIN 2011, EINECS 202-539-9, BRN 2220381, 3-Amino-alpha-ethyl-2,4,6-triiodohydrocinnamic acid, 2-Ethyl-3-(3-amino-2,4,6-triiodophenyl)propionic acid, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid, 3-Amino-alpha-ethyl-2,4,6-triiodobenzenepropanoic acid, CHEBI:5951, Benzenepropanoic acid, 3-amino-alpha-ethyl-2,4,6-triiodo-, OIRFJRBSRORBCM-UHFFFAOYSA-N, 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]butanoic acid, 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid, Hydrocinnamic acid, 3-amino-alpha-ethyl-2,4,6-triiodo-, Benzenepropanoic acid, 3-amino-.alpha.-ethyl-2,4,6-triiodo-, beta-(3-Amino-2,4,6-triiodophenyl)-alpha-ethylpropionic acid, DSSTox_CID_3159, DSSTox_RID_76897, DSSTox_GSID_23159, W-100130, (pm)-3-Amino-alpha-ethyl-2,4,6-triiodohydrocinnamic acid, Acido iopanoico, Acide iopanoique, Benzenepropanoic acid, 3-amino-alpha-ethyl-2,4,6-triiodo-, (+-)-, SR-05000001877, 3-[3-Amino-2,4,6-triiodophenyl]-2-ethylpropanoic acid, Iopanoic acid [INN:BAN:JAN], C11H12I3NO2, CAS-96-83-3, Telepaque (TN), NCGC00016357-01, Iopanoic acid [USP:INN:BAN:JAN], Spectrum_001576, AC1L1GLE, AC1Q4PCA, Prestwick0_001052, Prestwick1_001052, Prestwick2_001052, Prestwick3_001052, Spectrum2_001206, Spectrum4_000879, Spectrum5_001681, CHEMBL867, D0A5JP, (.+/-.)-Iopanoic acid, SCHEMBL38976, BSPBio_001004, KBioGR_001577, KBioSS_002056, MLS002154127, DivK1c_000902, SPECTRUM1503923, SPBio_000992, SPBio_002932, BPBio1_001106, Iopanoic acid (JAN/USP/INN), DTXSID6023159, CTK3J2080, HMS502N04, KBio1_000902, KBio2_002056, KBio2_004624, KBio2_007192, OIRFJRBSRORBCM-UHFFFAOYSA-, Hydrocinnamic acid,4,6-triiodo-, MolPort-003-666-506, NINDS_000902, HMS1571C06, HMS1922K20, HMS2093M03, HMS2098C06, HMS2231G12, HMS3369D07, HMS3715C06, Iopanoic acid, analytical standard, Pharmakon1600-01503923, Benzenepropanoic acid,4,6-triiodo-, HY-B1664, NSC41706, Tox21_110394, Tox21_303477, 6786AC, ANW-42001, CCG-39139, NSC-41706, NSC758646, AKOS015854598, Tox21_110394_1, API0024292, CS-8125, DB08946, NSC-758646, RTR-030833, VZ32411, IDI1_000902, WLN: ZR BI DI FI C1Y2 & VQ, NCGC00095082-01, NCGC00095082-02, NCGC00095082-03, NCGC00095082-06, NCGC00257386-01, AK116030, AN-42817, CC-29568, LS-77131, SMR001233434, SBI-0051863.P002, 2-(2-carbamimidoylsulfanylethyl)isothiourea, AX8013077, KB-221546, TR-030833, 2-(3-Amino-2,6-triiodobenzyl)butyric acid, AB00052387, FT-0631496, I0300, C08217, D01014, AB00052387_07, 2-(3-Amino-2,4,6-triiodobenzyl)butanoic acid #, C-23252, I04-0133, SR-05000001877-1, SR-05000001877-3, 2-Ethyl-3-(3-amino-2,6-triiodophenyl)propionic acid, 3-(3-Amino-2,6-triiodophenyl)-2-ethylpropanoic acid, 3-Amino-.alpha.-ethyl-2,6-triiodohydrocinnamic acid, BRD-A42628519-001-04-1, BRD-A42628519-001-07-4, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropionic Acid, 3-Amino-.alpha.-ethyl-2,4,6-triiodohydrocinnamic acid, 3-Amino-.alpha.-ethyl-2,4,6-triiodobenzenepropanoic acid, Hydrocinnamic acid, 3-amino-.alpha.-ethyl-2,4,6-triiodo-, Iopanoic acid, European Pharmacopoeia (EP) Reference Standard, .alpha.-Ethyl-.beta.-(3-amino-2,4,6-triiodophenyl)propionic acid, .beta.-(3-Amino-2,4,6-triiodophenyl)-.alpha.-ethylpropionic acid, .beta.-(3-Amino-2,6-triiodophenyl)-.alpha.-ethylpropionic acid, Benzenepropanoic acid, 3-amino-.alpha.-ethyl-2,4,6-triiodo-, (.+/-.)-, InChI=1/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)


ID: 1593

chemical graph of compound 1593



InChIKey: OIUBYZLTFSLSBY-HMGRVEAOSA-N
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5320844
synonyms found at PubChem are:
Spiraeoside, Spiraein, 20229-56-5, Spiraeosid, Spiraein (Acacia), Quercetin 4'-O-glucoside, Quercetin 4'-glucoside, Quercetin-4'-glucoside, UNII-K2B74751XI, EINECS 243-614-6, CHEMBL402947, CHEBI:75839, K2B74751XI, quercetin 4'-O-beta-D-glucopyranoside, 2-(4-(beta-D-Glucopyranosyloxy)-3-hydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)-3-hydroxyphenyl)-3,5,7-trihydroxy-, Spireoside, AC1NSZXI, Quercetin 4'-b-D-glucoside, Spireoside (6CI,7CI,8CI), SCHEMBL1155660, Spiraeoside, analytical standard, CTK8G3187, DTXSID00174078, MolPort-006-069-272, OIUBYZLTFSLSBY-HMGRVEAOSA-N, Quercetin 4'-O-beta-D-glucoside, ZINC4349687, BDBM50362884, AKOS025146959, API0004223, MCULE-3523271321, NCGC00163625-01, LS-39680, SC-88040, FT-0645061, Quercetin 4 inverted exclamation marka-glucoside, 229S565, J-013135, Quercetin 4 inverted exclamation marka-O-|A-D-glucopyranoside, 2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl beta-D-glucopyranoside, 3,3 inverted exclamation marka,4 inverted exclamation marka,5,7-Pentahydroxyflavone 4 inverted exclamation marka-glucoside, 3,5,7-trihydroxy-2-(3-hydroxy-4-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-4H-chromen-4-one, 3,5,7-trihydroxy-2-[3-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one, 4H-1-Benzopyran-4-one, 2-[4-(.beta.-D-glucopyranosyloxy)-3-hydroxyphenyl]-3,5,7-trihydroxy-


ID: 1594

chemical graph of compound 1594



InChIKey: OJENKXNXJPNEPU-HNCPQSOCSA-M
SMILES: C[C@H](C(=O)[O-])OC1=CC=C(C=C1)OC2=CN=C3C=CC(=CC3=N2)Cl.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957724
synonyms found at PubChem are:
XK469, UNII-4YM76775EY, 4YM76775EY, R-(+)-XK-469, XK-469, (R)-, CHEMBL1433897, CCG-205312, Propanoic acid, 2-(4-((7-chloro-2-quinoxalinyl)oxy)phenoxy)-, sodium salt (1:1), (2R)-, NCGC00094480-01, NCGC00094480-02, NCGC00094480-03, 157542-89-7, EU-0101238, X 3628, 2-(4-((7-Chloro-2-quinoxalinyl)oxy)phenoxy)propionic acid, UNII-G6S5600O0D component OJENKXNXJPNEPU-HNCPQSOCSA-M, (R)-2-[4-[(7-Chloroquinoxaline-2-yl)oxy]phenoxy]propanoic acid sodium salt


ID: 1595

chemical graph of compound 1595



InChIKey: OJGDCBLYJGHCIH-UHFFFAOYSA-N
SMILES: CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"KA Teske" "R Robert" "Y Luo" "JW Hanrahan" "GW Carlile" "DY Thomas" "D Zhang"


CID is 2442
synonyms found at PubChem are:
bromhexine, 3572-43-8, Bromhexinum, Bromhexina, Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, Bromexine, Bromhexine [INN:BAN], Bromhexinum [INN-Latin], Bromhexina [INN-Spanish], Bromhexine Monohydrochloride, UNII-Q1J152VB1P, 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline, C14H20Br2N2, EINECS 222-684-1, Q1J152VB1P, CHEBI:77032, OJGDCBLYJGHCIH-UHFFFAOYSA-N, N-Cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amin, 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline, 3,5-Dibromo-Nalpha-cyclohexyl-Nalpha-methyltoluene-alpha-2-diamine, NA 274, NA-274, Toluene-.alpha.,2-diamine, 3,5-dibromo-N.alpha.-cyclohexyl-N.alpha.-methyl-, [(2-amino-3,5-dibromophenyl)methyl]cyclohexylmethylamine, 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline, Flegamin, SMR001826324, Tauglicolo, Bromexina, Fluibron, Fluibron (TN), Bromhexine (INN), Spectrum_001392, AC1L1DOQ, Spectrum2_001526, Spectrum3_001152, Spectrum4_000758, Spectrum5_001054, Oprea1_147116, SCHEMBL19059, BSPBio_002703, KBioGR_001116, KBioSS_001872, MLS004774079, MLS006011815, DivK1c_000455, SPBio_001312, CHEMBL253376, DTXSID6022686, CTK5I6419, KBio1_000455, KBio2_001872, KBio2_004440, KBio2_007008, KBio3_002203, OJGDCBLYJGHCIH-UHFFFAOYSA-, MolPort-000-887-467, NINDS_000455, HMS2090K17, ZINC608220, 611-75-6 (mono-hydrochloride), BBL022746, MFCD00436295, SBB021209, STK177356, AKOS000305902, ACM3572438, API0007117, DB09019, MCULE-1869883185, IDI1_000455, NCGC00178520-01, NCGC00178520-02, NCGC00178520-05, AJ-23700, AK129825, Q563, ST024771, SBI-0051773.P002, AX8118823, KB-225470, LS-174556, D07542, EN300-228940, AB00053644-02, AB00053644_03, AB00053644_04, BRD-K47631482-003-02-1, BRD-K47631482-003-03-9, F2173-0412, N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 2,4-Dibromo-6-([cyclohexyl(methyl)amino]methyl)aniline #, 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemathanamine, N-2-AMINO-3,5-DIBROMOBENZYL-N-CYCLOHEXYLMETHYLAMINE, 2,4-Dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline (HCl), 2-Amino-3,5-dibromo-N-cyclohexyl-N-methyl benzenemethanamine, N-(2-AMINO-3,5-DIBROMOBENZYL)-N-CYCLOHEXYL-N-METHYLAMINE, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine, InChI=1/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17/h7-8,12H,2-6,9,17H2,1H3


ID: 1596

chemical graph of compound 1596



InChIKey: OJOBTAOGJIWAGB-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC(=C(C(=C1)OC)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 17198
synonyms found at PubChem are:
Acetosyringone, 2478-38-8, 3',5'-Dimethoxy-4'-hydroxyacetophenone, 1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone, 4'-HYDROXY-3',5'-DIMETHOXYACETOPHENONE, 3,5-Dimethoxy-4-hydroxyacetophenone, Acetosyringon, Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)-, Acetosyringenin, 1-(4-hydroxy-3,5-dimethoxyphenyl)ethan-1-one, Acetophenone, 4'-hydroxy-3',5'-dimethoxy-, CCRIS 7286, UNII-866P45Y84S, 4-hydroxy-3,5-dimethoxyacetophenone, EINECS 219-610-5, 4-Hydroksy-3',5'-dwumetoksyacetofenon, BRN 1966119, Acetophenone, 3,5-dimethoxy-4-hydroxy-, CHEBI:2404, OJOBTAOGJIWAGB-UHFFFAOYSA-N, 4-Hydroksy-3',5'-dwumetoksyacetofenon [Polish], 866P45Y84S, 1-(4-Hydroxy-3,5-dimethoxy-phenyl)-ethanone, 1-acetyl-4-hydroxy-3,5-dimethoxybenzene, 4-acetylsyringol, Spectrum_001915, ACMC-209gen, SpecPlus_000955, AC1Q5DJC, Spectrum2_000429, Spectrum3_001115, Spectrum4_001953, Spectrum5_000695, bmse000576, bmse010032, AC1L29IZ, AC1Q47JK, AC1Q47JL, SCHEMBL15511, BSPBio_002850, KBioGR_002389, KBioSS_002457, SPECTRUM300610, KSC496O9N, MLS002207209, DivK1c_007051, 4-acetyl-2,6-dimethoxyphenol, SPBio_000418, CHEMBL224146, Jsp004937, DTXSID2062454, CTK3J6796, KBio1_001995, KBio2_002450, KBio2_005018, KBio2_007586, KBio3_002070, MolPort-001-759-184, Phenol, 4-acetyl-2,6-dimethoxy, ZINC156899, KS-00000ZW1, ANW-25533, CCG-39967, MFCD00008748, SBB071453, AKOS005258861, 3',5-Dimethoxy-4'-hydroxyacetophenone, CS-W010600, MCULE-7881518363, RTR-011399, SDCCGMLS-0066948.P001, NCGC00095819-01, NCGC00095819-02, 3', 5'-dimethoxy-4'-hydroxyacetophenone, AJ-13905, AN-50981, CJ-01556, KB-28748, L910, LS-13513, SMR000112388, ST093688, ZB006467, AB0014955, AB1004202, DB-022069, TR-011399, 1-(4-hydroxy-3,5-dimethoxy-phenyl)ethanone, A5075, D2666, FT-0634308, 1-(3,5-dimethoxy-4-oxidanyl-phenyl)ethanone, 3',5'-Dimethoxy-4'-hydroxyacetophenone, 97%, C10664, K-6581, 478D388, A817490, SR-05000002436, A1-00327, Acetophenone, 4'-hydroxy-3',5'-dimethoxy- (8CI), I01-8777, SR-05000002436-1, W-107282, BRD-K66643401-001-02-4, BRD-K66643401-001-04-0, Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)- (9CI), Z2418193700, 4 inverted exclamation marka-Hydroxy-3 inverted exclamation marka,5 inverted exclamation marka-dimethoxyacetophenone; Acetosyringone, InChI=1/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H


ID: 1597

chemical graph of compound 1597



InChIKey: OKBNMQXBQLZQEM-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(O1)C=C3C(=C2OC)C(=O)C(=CO3)C4=CC5=C(C=C4)OCO5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 3473650
synonyms found at PubChem are:
METHYL ROBUSTONE, Robustone methyl ether, KBio2_006984, AC1MRTBY, Spectrum_001368, SpecPlus_000487, Spectrum2_000826, Spectrum3_001775, Spectrum4_001835, Spectrum5_000629, BSPBio_003269, KBioGR_002536, KBioSS_001848, DivK1c_006583, SPECTRUM1401401, SPBio_000751, CHEMBL1403041, KBio1_001527, KBio2_001848, KBio2_004416, KBio3_002770, CHEBI:109548, CCG-39544, LMPK12050345, SDCCGMLS-0066877.P001, NCGC00095746-01, NCGC00095746-02, NCGC00178176-01, SR-05000002631, SR-05000002631-1, BRD-K25811799-001-02-7, BRD-K25811799-001-03-5, 7-(1,3-benzodioxol-5-yl)-5-methoxy-2,2-dimethylpyrano[3,2-g]chromen-6-one


ID: 1598

chemical graph of compound 1598



InChIKey: OKBVVJOGVLARMR-QSWIMTSFSA-N
SMILES: C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5362065
synonyms found at PubChem are:
CEFIXIME, 79350-37-1, Cefixima, Cefiximum, Cefspan, Cephoral, Cefixoral, Cefixim, Cefiximum [Latin], FK-027, Suprax, Necopen, Denvar, Tricef, UNII-XZ7BG04GJX, FR-17027, CL-284635, Unixime, Suprax (TN), CFIX, Cefixima [Spanish], XZ7BG04GJX, (-)-Cefixim, MLS002222332, Cefixime Anhydrous, CHEBI:472657, SMR001307271, (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, BRN 6025058, (6r,7r)-7-[-2-(2-amino-thiazol-4-yl)-2-carboxymethoxyimino-acetylamino]-8-oxo-3-vinyl-5-thia-1-aza-b, (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethyloxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(carboxymethyl)oxy]imino}acetyl]amino}-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid, cefiximine, (6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-(carboxymethyl)oxime) trihydrate, Cefixime [USAN:USP:INN:BAN:JAN], Ofex (TN), AC1NSFNI, PubChem13762, Prestwick3_000462, D06OVY, Cefixime (JAN/USP/INN), CHEMBL1541, SCHEMBL24945, BSPBio_000564, Cefixime (JP15/USP/INN), BPBio1_000622, BDBM84007, cid_5362065, MolPort-003-845-687, HMS2096M06, HMS2234J21, HMS3713M06, (6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-(carboxymethyl)oxime)trihydrate, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)((carboxymethoxy)imino)acetyl)amino)-3-ethenyl-8-oxo-, trihydrate, (6R-(6alpha,7beta(Z)))-, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)((carboxymethoxy)imino)acetyl)amino)-3-ethenyl-8-oxo-, (6R,7R)-, HY-B1381, RS0002, s4596, ZINC12503147, AKOS015854940, AKOS015961135, AC-4350, AT-7061, CCG-220462, CS-4820, DB00671, NCGC00179521-01, BC205782, AB0073052, FR- 17027, LS-187248, TC-070894, AB00513842, Cefixime EP Impurity C (Cefixime 7-epimer), CL 284,635, 50C371, C06881, D00258, X-2622, Cefixime, Antibiotic for Culture Media Use Only, SR-01000760706, SR-01000760706-4, BRD-K71059170-001-02-5, BRD-K71059170-001-08-2, (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-[-2-(2-Amino-thiazol-4-yl)-2-carboxymethoxyimino-acetylamino]-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4. 2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (6R,7R)-7-[[(2z)-2-(2-amino-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]Oct-2-ene-2-carboxylic acid, 214265-67-5, C04, Cefixime(7-[[(2-amino-4-thiazolgl)(Carboxymethoxg)imino]acetyl]amino-3-vinyl -8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-Carboxylicacidtrihydrate)


ID: 1599

chemical graph of compound 1599



InChIKey: OKCRIUNHEQSXFD-UHFFFAOYSA-N
SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 119442
synonyms found at PubChem are:
GALLOPAMIL HYDROCHLORIDE, Procorum, 16662-46-7, Methoxyverapamil hydrochloride, Gallopamil HCl, EINECS 240-704-7, NSC 274966, D600, HCl, MLS000069359, (+/-)-Methoxyverapamil, Hydrochloride, 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride, SMR000058477, (+/-)-Methoxyverapamil hydrochloride, [3-cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl]-(5,6-dimethoxyphenethyl)methylammonium chloride, DSSTox_CID_27844, DSSTox_RID_82597, DSSTox_GSID_47858, Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4,5-trimethoxy-alpha-(1-methylethyl)-, monohydrochloride, (3-Cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl)-(5,6-dimethoxyphenethyl)methylammonium chloride, 56949-75-8, CAS-16662-46-7, D 600 Hydrochloride, NCGC00015686-05, gallopamil hydrochloride(jan), D600; Gallopamil, AC1L3OTK, Opera_ID_1611, AC1Q3CE7, (+/-)-Methoxyverapamil HCl, C28H40N2O5.HCl, SCHEMBL194931, Gallopamil hydrochloride (JAN), CHEMBL1256940, DTXSID2047858, CTK1H2932, KS-00002WUB, MolPort-009-194-164, (?)-Methoxyverapamil hydrochloride, (y)-Methoxyverapamil hydrochloride, Tox21_110196, Tox21_500778, NSC274966, AKOS015994622, Tox21_110196_1, CCG-222082, HS-0066, LP00778, NSC-274966, NCGC00015686-11, NCGC00094115-01, NCGC00261463-01, LS-29041, LU-30029, EU-0100778, FT-0727258, X3808, (+/-)-Methoxyverapamil hydrochloride, >=98%, D01969, M 5644, C-46073, SR-01000000018, J-010303, SR-01000000018-2, ( inverted question mark)-Methoxyverapamil hydrochloride, 5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride, 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride, AC1LCW8C, 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile; hydron; chloride


ID: 1600

chemical graph of compound 1600



InChIKey: OLBCVFGFOZPWHH-UHFFFAOYSA-N
SMILES: CC(C)C1=C(C(=CC=C1)C(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4943
synonyms found at PubChem are:
propofol, 2,6-DIISOPROPYLPHENOL, 2078-54-8, Diprivan, Disoprofol, Disoprivan, Diisopropylphenol, Fresofol, Ampofol, 2,6-Bis(1-methylethyl)phenol, Propofolum, Rapinovet, Recofol, Ivofol, Phenol, 2,6-bis(1-methylethyl)-, Propofol-Lipuro, Pofol, ICI 35868, Propofolum [Latin], Aquafol, Diprifusor, Diprofol, Propovan, Phenol, 2,6-diisopropyl-, 2,6-bis(propan-2-yl)phenol, 2,6-Diisopropyl phenol, Diprivan 10, Diprivan Injectable emulsion, 2,6-di(propan-2-yl)phenol, 2,6 Diisopropylphenol, Dipravan, UNII-YI7VU623SF, NSC 5105, Propofol IDD-D, ICI-35868, Diprivan (TN), Propofol [USAN:INN:BAN], CCRIS 9000, HSDB 7123, C12H18O, 2, 6-Diisopropylphenol, EINECS 218-206-6, 2,6-bis(Isopropyl)phenol, CHEMBL526, BRN 1866484, YI7VU623SF, Propofol (JAN/USAN/INN), DDS-04F, ghl.PD_Mitscher_leg0.558, AI3-26295, CHEBI:44915, NSC5105, OLBCVFGFOZPWHH-UHFFFAOYSA-N, ZD-0859, NCGC00015389-08, CAS-2078-54-8, DSSTox_CID_3523, DSSTox_RID_77063, DSSTox_GSID_23523, PFL, Propoven, Aquafo, Propofol Abbott, Propofol Rovi, Propofol MCT, Propofol Fresenius, SMR000059151, SR-01000075468, Propofol(2,6-Diisopropylphenol), Propofol [USAN:USP:INN:BAN], Propofol (Diprivan), ICI 35,868, ICI-35,868, Phenol,6-diisopropyl-, Pisa Brand of Propofol, Rovi Brand of Propofol, 2,6-diisopropyl-phenol, ACMC-1CPLW, Alpha Brand of Propofol, Astra Brand of Propofol, Braun Brand of Propofol, Juste Brand of Propofol, Abbott Brand of Propofol, AC1Q1OUI, Zeneca Brand of Propofol, Prestwick0_000931, Prestwick1_000931, Prestwick2_000931, Prestwick3_000931, 2,6-di isopropyl phenol, Curamed Brand of Propofol, Parnell Brand of Propofol, Biomol-NT_000248, D0A3HB, Lopac-D126608, Schering Brand of Propofol, Diisopropylphenol (Related), AC1L1J9Y, Fresenius Brand of Propofol, 2,6-bis(methylethyl)phenol, 2,6-Bis(Isopropyl)-phenol, Lopac0_000437, SCHEMBL36245, BSPBio_000862, 4-06-00-03435 (Beilstein Handbook Reference), AstraZeneca Brand of Propofol, KSC490K5P, MLS001066348, MLS001335999, MLS002454360, BIDD:GT0436, SPECTRUM1505022, SPBio_003031, 2,6-Diisopropylphenol, 97%, BPBio1_000950, BPBio1_000969, GTPL5464, Phenol,6-bis(1-methylethyl)-, Jsp004266, DTXSID6023523, 2,6-bis(1-methylethyl)-phenol, CTK3J0557, Fresenius Kabi Brand of Propofol, Propofol 1.0 mg/ml in Methanol, 2,6-Diisopropylphenol, >=97%, 3f33, 3p50, HMS1570L04, HMS2089O21, HMS2094E17, HMS2097L04, HMS2231E16, HMS3259E03, HMS3261G16, HMS3369I16, HMS3714L04, Pharmakon1600-01505022, ZINC968303, BCP02920, KS-00000MQ0, NSC-5105, Tox21_110134, Tox21_201371, Tox21_303225, Tox21_500437, AM-149, ANW-24224, BDBM50058046, CP0141, LS-996, MFCD00008885, NSC758909, Phenol, 2, 6-bis(1-methylethyl)-, AKOS009159417, Tox21_110134_1, AC-2038, AM90311, AN-3506, CCG-204529, CS-W020057, DB00818, LP00437, MCULE-1903292305, NC00449, NSC-758909, RP23984, RTR-009757, TRA0038441, VZ22957, MLS-0318084, NCGC00015389-01, NCGC00015389-02, NCGC00015389-03, NCGC00015389-04, NCGC00015389-05, NCGC00015389-06, NCGC00015389-07, NCGC00015389-09, NCGC00015389-10, NCGC00015389-11, NCGC00015389-14, NCGC00091538-01, NCGC00091538-02, NCGC00091538-03, NCGC00091538-04, NCGC00091538-05, NCGC00091538-06, NCGC00257228-01, NCGC00260670-01, NCGC00261122-01, AJ-24593, AS-13299, CJ-04649, CPD000059151, H835, SAM002264610, SC-18796, ZB015550, 2,6-Diisopropylphenol, analytical standard, BCP0726000298, MLS-0318084.P017, ST2415947, TR-009757, AB00513968, D0617, EU-0100437, FT-0610672, ST50405911, C07523, D00549, AB00513968-07, AB00513968_08, A814898, D126608, Q-201631, S01-0189, SR-01000075468-1, SR-01000075468-4, SR-01000075468-6, BRD-K82255054-001-03-5, BRD-K82255054-001-08-4, Propofol, British Pharmacopoeia (BP) Reference Standard, Propofol, European Pharmacopoeia (EP) Reference Standard, Z1245735300, Propofol, United States Pharmacopeia (USP) Reference Standard, Propofol, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H, Propofol for peak identification, European Pharmacopoeia (EP) Reference Standard, 28449-97-0, 50356-15-5


ID: 1601

chemical graph of compound 1601



InChIKey: OLBNOBQOQZRLMP-UHFFFAOYSA-N
SMILES: COC1=CC(=O)C=C(C1=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 68262
synonyms found at PubChem are:
2,6-Dimethoxy-1,4-benzoquinone, 530-55-2, 2,6-Dimethoxy-p-benzoquinone, 2,6-Dimethoxyquinone, 2,6-Dimethoxybenzoquinone, 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione, 2,6-Dimethoxy-p-quinone, 2,6-Dimethoxysemiquinone anions, 2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-, NSC 24500, DMBQ, UNII-1Z701W789S, p-Benzoquinone, 2,6-dimethoxy-, 2,6-Dimethoxybenzo-1,4-quinone, 2,6-Dimethoxysemiquinone radicals, NSC24500, EINECS 208-484-7, ghl.PD_Mitscher_leg0.4, MLS002207260, 2,6-Dimethoxy-2,5-cyclohexadiene-1,4-dione, OLBNOBQOQZRLMP-UHFFFAOYSA-N, NSC-56336, 1Z701W789S, SMR001306787, p-Benzoquinone,6-dimethoxy-, 2,4-dione, 2,6-dimethoxy-, DIMETHOXYBENZOQUINONE,6-, 2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy- (9CI), 2,6- dimethoxyquinone, Spectrum_000723, 2, 6-Dimethoxyquinone, Maybridge1_002628, Spectrum2_000781, Spectrum3_000177, Spectrum4_001608, Spectrum5_000335, ACMC-1AV4R, Quinone, 2,6-dimethoxy-, AC1L29DM, AC1Q6D2N, 2,6-Dimetoxy-p-benzoquinone, BSPBio_001673, KBioGR_001955, KBioSS_001203, SPECTRUM200413, cid_68262, DivK1c_001380, SCHEMBL570683, SPBio_000882, 2, 6-Dimethoxy-p-benzoquinone, 2,6-DMBQ, CHEMBL448515, BDBM80763, CTK4J6953, HMS548P10, KBio2_001203, KBio2_003771, KBio2_006339, KBio3_001173, OLBNOBQOQZRLMP-UHFFFAOYSA-, 2,6-dimethoxy[1,4]benzoquinone, 3,5-Dimethoxy-1,4-benzoquinone, MolPort-001-790-115, HMS1922P16, ZINC137119, 2, 6-Dimethoxy-1,4-benzoquinone, 2,6-dimethoxy-[1,4]benzoquinone, DIMETHOXYBENZOQUINONE,2,6-, NSC56336, ACM530552, ANW-31618, CCG-40159, NSC-24500, SBB057170, AKOS015851594, FCH1117576, MCULE-5661538939, SDCCGMLS-0066389.P001, VZ22964, ACM33070416, CDS1_000340, 2,6-Dimethoxy-1,4-benzoquinone, 97%, NCGC00095215-01, NCGC00095215-02, NCGC00095215-03, NCGC00095215-04, 26547-64-8, 4CN-0706, CC-08145, KB-18363, LS-40349, NCI60_001958, DB-020224, ST2415953, TR-018777, D2706, FT-0610674, ST50331798, W2131, 2,5-Cyclohexadiene-1,4-dione,2,6-dimethoxy-, C10331, A829370, C-05000, SR-05000002399, SR-05000002399-1, I01-17714, 2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-, radical ion(1-), InChI=1/C8H8O4/c1-11-6-3-5(9)4-7(12-2)8(6)10/h3-4H,1-2H3, KIA


ID: 1602

chemical graph of compound 1602



InChIKey: OLISZPLPWWXTJP-UUXCHQRJSA-N
SMILES: C[C@@]12CCC3C(=C)C1(CC(=O)O[C@H]2C4=COC=C4)OC5[C@]3([C@H]6CC(=O)O[C@@H](C5)C6(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 98042583
synonyms found at PubChem are:
DIHYDROANGOLENSIC LACTONE


ID: 1603

chemical graph of compound 1603



InChIKey: OLNTVTPDXPETLC-XPWALMASSA-N
SMILES: C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 150311
synonyms found at PubChem are:
Ezetimibe, 163222-33-1, Zetia, Ezetrol, Ezedoc, ezetimib, Sch 58235, SCH-58235, (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one, Zient, Ezetimibe [USAN:INN], UNII-EOR26LQQ24, SCH58235, (-)-Sch 58235, Ezetimibe (Zetia), Zetia (TN), EOR26LQQ24, Ezetimibe (JAN/USAN/INN), CHEBI:49040, 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, MK-0653, DSSTox_CID_24223, DSSTox_RID_80127, DSSTox_GSID_44223, (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one, (3R,4S)-1-(p-Fluorophenyl)-3-((3S)-3-(p-fluorophenyl)-3-hydroxypropyl)-4-(p-hydroxyphenyl)-2-azetidinone, 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-(4-hydroxyphenyl)-2-azetidione, (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, 2-Azetidinone, 1-(4-fluorophenyl)-3-((3S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-, (3R,4S)-, 2-Azetidinone, 1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-, (3R-(3alpha(S*),4beta))-, SMR000466334, CAS-163222-33-1, MSD brand of ezetimibe, Essex brand of ezetimibe, Merck brand of ezetimibe, ezentia, ezetimiba, ezetimibum, Ezetimibe [USAN:INN:BAN], Zetia ;Ezetrol, C24H21F2NO3, HSDB 7737, Schering-Plough brand of ezetimibe, NCGC00095134-01, 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-, Vytorin (TN), Inegy (TN), D09LWS, SCHEMBL2871, Zetia , Ezetrol, Ezetimibe, CHEMBL1138, MLS000759443, MLS001424125, MLS006011921, AC1L442L, GTPL6816, DTXSID1044223, Ezetimibe, >=98% (HPLC), EX-A795, MolPort-005-938-627, OLNTVTPDXPETLC-XPWALMASSA-N, HMS2051K16, HMS2236A04, HMS3715D06, ACT03511, AMX10142, ZINC3810860, Tox21_111443, ABP001091, BDBM50371521, s1655, STK640490, AKOS005572111, Tox21_111443_1, AC-1057, AM84560, AN-5188, CCG-100884, CS-1016, DB00973, KS-1170, MCULE-4417284526, NC00134, RL02093, NCGC00263575-01, NCGC00263575-07, (1-(4-fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone), BC216471, CPD000466334, HY-17376, SAM001246623, SC-17354, AB0011316, AB2000199, LS-181801, FT-0601590, D01966, K-5098, 28055-EP2272841A1, 28055-EP2280001A1, 28055-EP2287165A2, 28055-EP2287166A2, 28055-EP2292620A2, 28055-EP2294052A1, 28055-EP2295422A2, 28055-EP2298742A1, 28055-EP2298769A1, 28055-EP2298776A1, 28055-EP2301923A1, 28055-EP2301936A1, 28055-EP2308878A2, 28055-EP2314588A1, AB00639916-06, AB00639916-08, AB00639916_09, 222E331, 3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one, BRD-K42260897-001-09-2, Z1550648770, (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-, Ezetimibe, United States Pharmacopeia (USP) Reference Standard, Ezetimibe, Pharmaceutical Secondary Standard; Certified Reference Material, (3R,4S)-1-(4-fluorophenyl)-3-[(3 S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one, (3R,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-azetidin-2-one


ID: 1604

chemical graph of compound 1604



InChIKey: OLOCXIJVDIVAHH-FXRZFVDSSA-N
SMILES: CC1=C(SC=C1)/C=C/C2=NCCCN2C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5702276
synonyms found at PubChem are:
MORANTEL CITRATE, Morantel citrate salt, 69525-81-1, UNII-VC8Z4SS5QX, VC8Z4SS5QX, EINECS 274-028-9, Exhelm (TN), AC1NWAY4, MLS004712037, SPECTRUM1503931, SCHEMBL2777336, CHEMBL1330312, HMS502L08, DTXSID90219780, MolPort-003-666-511, HMS1922M08, HMS2093M11, Pharmakon1600-01503931, EX-A1463, CCG-39377, MFCD00079447, NSC758647, AKOS024255719, HS-0101, NSC-758647, NCGC00095083-01, NCGC00095083-02, (E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidinediylium hydrogen citrate, SMR003475008, D08231, SR-01000721901-2, (E)-1-methyl-2-(2-(3-methylthiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine 2-hydroxypropane-1,2,3-tricarboxylate, 2-hydroxypropane-1,2,3-tricarboxylic acid,1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine, 2-hydroxypropane-1,2,3-tricarboxylic acid; 1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine


ID: 1605

chemical graph of compound 1605



InChIKey: OLSYHLURTGEIBH-UHFFFAOYSA-N
SMILES: C1=CC(=O)C(=C2C(=C1)C=CC(=C2O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 822798
synonyms found at PubChem are:
64782-84-9, Spectrum_000350, SpecPlus_000313, AC1LGK8W, Spectrum2_000553, Spectrum3_000250, Spectrum4_001548, Spectrum5_000116, Oprea1_493780, BSPBio_001640, KBioGR_002016, KBioSS_000830, DivK1c_006409, SCHEMBL193772, SPBio_000625, CHEMBL3964783, CTK8J8496, KBio1_001353, KBio2_000830, KBio2_003398, KBio2_005966, KBio3_001140, ZINC340395, CCG-39557, AKOS022505976, 3,4,5-trihydroxybenzo[7]annulen-6-one, NCGC00179129-01, KB-286581, 3,4,6-Trihydroxy-5H-benzocycloheptene-5-one, 3,4,6-trihydroxy-5H-benzo[a]cyclohepten-5-one, 6H-Benzocyclohepten-6-one, 3,4,5-trihydroxy- (9CI)


ID: 1606

chemical graph of compound 1606



InChIKey: OLUNPKFOFGZHRT-YGCVIUNWSA-N
SMILES: CN(C/C=C/C1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5281098
synonyms found at PubChem are:
NAFTIFINE HYDROCHLORIDE, 65473-14-5, Naftifine HCl, Naftin, Exoderil, Naftifungin, Naftifine (hydrochloride), UNII-25UR9N9041, AW 105-843, AW 105843, SN 105843, CHEBI:7452, MFCD00059047, 25UR9N9041, (E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride, N-trans-Cinnamyl-N-methyl-(1-naphthylmethyl)amine Hydrochloride, AW-105-843, Naftin (TN), (E)-N-methyl-N-(1-naphthylmethyl)-3-phenyl-2-propen-1-amine- hydrochloride, (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride, DSSTox_CID_25496, DSSTox_RID_80915, DSSTox_GSID_45496, (E)-N-Methyl-N-(3-phenyl-2-propen-1-yl)-1-naphthalenemethanamine Hydrochloride, 1-Naphthalenemethanamine, N-methyl-N-(3-phenyl-2-propenyl)-, hydrochloride, (E)-, Suadian, Naftifine hydrochloride [USAN], Naftifine, HCl, Naftin hydrochloride, Naftifine hydrochloride [USAN:USP], AC1NQY0T, NCGC00016908-01, CAS-65473-14-5, SureCN1649698, SCHEMBL41356, MLS002154136, NAFTIFENE HYDROCHLORIDE, Naftifine Hydrochloride ,(S), Naftifine hydrochloride (USP), NAFT-600, SCHEMBL4932462, CHEMBL1200493, DTXSID2045496, HY-B0518A, MolPort-003-666-692, HMS1571E08, Pharmakon1600-01505446, naftifin hydrochloride, (E)-isomer, BCP07446, Tox21_110677, NSC760068, s3156, AKOS015895211, Tox21_110677_1, AB02353, AC-1120, API0000683, CCG-213447, CS-2730, H72N880, NSC-760068, NCGC00179332-03, AN-15212, AS-13296, BC679571, H827, SMR001233443, AB0013289, AW-105843, LS-176455, SN-105843, C1162, C08072, D00883, J10185, A835130, C-19785, SR-01000838853, I06-0253, SR-01000838853-2, (E)-N-Cinnamyl-N-methyl-1-naphthalenemethanamine Hydrochloride, (E)-N-CINNAMYL-N-METHYL(1-NAPHTHYLMETHYL)AMINE HYDROCHLORIDE, N-trans-Cinnamyl-N-methyl-(1-napphthylmethyl)amine hydrochloride, N-Methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride, Naftifine hydrochloride, United States Pharmacopeia (USP) Reference Standard, (E)-N-methyl-N-(1-naphthalenylmethyl)-3-phenyl-2-propen-1-amine hydrochloride, (E)-N-methyl-N-(1-naphthylmethyl)-3-phenyl-prop-2-en-1-amine hydrochloride, (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenyl-prop-2-en-1-amine hydrochloride, AKOS026750142


ID: 1607

chemical graph of compound 1607



InChIKey: OMCOKCNIYWULQH-UHFFFAOYSA-N
SMILES: CCOC(=O)NNC1=NN=CC2=CC=CC=C21.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 19604
synonyms found at PubChem are:
Todralazine hydrochloride, Ecarazine, 3778-76-5, Apirachol, Binazin, Binazine, Ecarazine hydrochloride, 621-BT hydrochloride, UNII-C59540FEXP, CCRIS 5090, C59540FEXP, Todralazine HCl, N1-Ethoxy carbonyl-N2-hydrazinophthalazine hydrochloride, DSSTox_CID_24664, DSSTox_RID_80385, DSSTox_GSID_44664, CARBAZIC ACID, 3-(1-PHTHALAZINYL)-, ETHYL ESTER, MONOHYDROCHLORIDE, SR-01000841205, NCGC00016640-03, CAS-3778-76-5, Todralazine hydrochloride [JAN], Prestwick_899, AC1L2EGT, C11H13ClN4O2, MLS002154190, SCHEMBL211261, SPECTRUM1501174, CHEMBL1318529, DTXSID4044664, CTK4H8818, MolPort-003-666-376, HMS1568O03, HMS1921N09, Pharmakon1600-01501174, Tox21_113562, Tox21_301437, 2-(1-Phthalazinyl)-hydrazinecarboxylic acid ethyl ester hydrochloride, CCG-40263, NSC757868, AKOS015963889, AKOS024375001, Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride, Tox21_113562_1, ACM3778765, API0013666, MCULE-7836122954, NSC-757868, NCGC00016640-06, NCGC00094919-01, NCGC00094919-02, NCGC00256213-01, AC-18055, LS-51663, O389, SMR001233481, FT-0714739, ST51015161, D01951, C-44334, SR-01000841205-2, SR-01000841205-3, ethyl N-(phthalazin-1-ylamino)carbamate hydrochloride, ethyl N-(phthalazin-1-ylamino)carbamate,hydrochloride, Ethyl 2-(phthalazin-1-yl)hydrazinecarboxylate hydrochloride, ethoxy-N-(2-hydrophthalazinylideneazamethyl)carboxamide, chloride, Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride (9CI), Hydrazinecarboxylicacid, 2-(1-phthalazinyl)-, ethyl ester, hydrochloride (1:1)


ID: 1608

chemical graph of compound 1608



InChIKey: OMFXVFTZEKFJBZ-HJTSIMOOSA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5753
synonyms found at PubChem are:
CORTICOSTERONE, 50-22-6, 17-Deoxycortisol, Reichstein's substance H, Kendall's compound B, Corticosteron, 11beta,21-Dihydroxyprogesterone, Compound B, Reichstein's B, 11-Hydroxycorticoaldosterone, (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione, 11beta,21-Dihydroxy-4-pregnene-3,20-dione, 4-Pregnene-11beta,21-diol-3,20-dione, 11,21-Dihydroxyprogesterone, 11Beta,21-dihydroxypregn-4-ene-3,20-dione, 11,12-Dihydroxyprogesterone, UNII-W980KJ009P, CCRIS 6753, 11-beta,21-Dihydroxypregn-3,20-dione, CHEBI:16827, NSC9705, 11-beta,21-Dihydroxyprogesterone, 4-Pregnene-11-beta,21-diol-3,20-dione, NSC 9705, Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11beta)-, EINECS 200-019-6, Pregn-4-ene-3,20-dione, 11beta,21-dihydroxy-, BRN 2339601, Pregn-4-ene-3,20-dione, 11-beta,21-dihydroxy-, (11-beta)-11,21-Dihydroxypregn-4-ene-3,20-dione, MLS000028536, CHEMBL110739, OMFXVFTZEKFJBZ-HJTSIMOOSA-N, W980KJ009P, 11.beta.,21-Dihydroxyprogesterone, NSC-9705, (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, NCGC00022472-05, SMR000058318, DSSTox_CID_2474, DSSTox_RID_76598, DSSTox_GSID_22474, Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11b)-, (11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE, C0R, Compound B nach Kendall, SR-01000075748, Substanz H nach Reichstein, Cortico, Compd B, CAS-50-22-6, Prestwick_672, Kendalls Compound B, 11Beta,21-dihydroxy-4-prenene-3,20-dione, Reichsteins Substance H, 21-dihydroxyprogesterone, Opera_ID_1519, Prestwick0_000432, Prestwick1_000432, Prestwick2_000432, Prestwick3_000432, Corticosterone, >=92%, 11-.beta.,20-dione, bmse000669, D01TDR, D03TNT, Epitope ID:152207, BIDD:PXR0063, Lopac0_000220, SCHEMBL22612, BSPBio_000444, 4-Pregnene-11 Corticosteron, MLS001074095, MLS001424305, Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11.beta.)-, BIDD:ER0495, SPBio_002383, AC1L1L28, BPBio1_000490, GTPL2869, DTXSID6022474, CTK8B4095, Corticosterone, BRN 2339601, 4-Pregnene-11.beta.,20-dione, MolPort-002-512-114, HMS1569G06, HMS2052G21, HMS2090A08, HMS2096G06, HMS2231F16, HMS3260L21, HMS3713G06, HY-B1618, Tox21_110879, Tox21_201366, Tox21_303642, Tox21_500220, 6866AB, ANW-43873, BDBM50170653, CMC_13412, HSCI1_000383, LMST02030186, MFCD00037715, s4752, ZINC13513592, Corticosterone, >=98.5% (HPLC), AKOS016008541, Tox21_110879_1, 11-b,21-Dihydroxypregn-3,20-dione, ACN-036935, CCG-101146, CS-5105, DB04652, LP00220, MCULE-1874567277, NC00396, SMP1_000079, NCGC00022472-06, NCGC00022472-07, NCGC00022472-08, NCGC00022472-10, NCGC00091029-01, NCGC00256539-01, NCGC00258918-01, NCGC00260905-01, 11|A, AJ-64002, LS-54984, SC-47259, 11,21-Dihydroxypregn-4-ene-3,20-dione, 11-.beta.,21-Dihydroxypregn-3,20-dione, 11b,21-Dihydroxy-4-pregnene-3,20-dione, Pregn-4-ene-3, 11.beta.,21-dihydroxy-, ST2412747, TR-017949, 4-Pregnen-11.beta.,21-diol-3,20-dione, 4-Pregnene-11.beta.,21-diol-3,20-dione, B7469, EU-0100220, 7061-EP2269977A2, 7061-EP2270008A1, 7061-EP2272835A1, 7061-EP2272844A1, 7061-EP2292228A1, 7061-EP2292617A1, 7061-EP2295411A1, 7061-EP2301931A1, 7061-EP2308851A1, C 2505, C02140, Preg-4-ene-3,20-dione,11-b,21-dihydroxy-, 11.beta.,21-dihydroxypregn-4-ene-3,20-dione, Corticosterone, VETRANAL(TM), analytical standard, SR-01000000082, (11?)-11,21-Dihydroxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 11.beta.,21-dihydroxy-, SR-01000000082-3, SR-01000075748-1, SR-01000075748-4, W-105977, WLN: L E5 B666 OV MUTJ A1 CQ E1 FV1Q, BRD-K73589401-001-04-6, Pregn-4-ene-3, 11,21-dihydroxy-, (11.beta.)-, (11.beta.)-11,21-Dihydroxypregn-4-ene-3,20-dione, 11,21-Dihydroxypregn-4-ene-3,20-dione, (11.beta.)- #, 4793EB71-D789-498E-B641-C5C1C377B9FF, Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11-beta)-, 17-Deoxycortisol;11|A,21-Dihydroxyprogesterone;Kendalls compound B, Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11-beta)- (9CI), Kendall's Compound B; 4-Pregnene-11beta,21-diol-3,20-dione; Reichstein's Substance H, Corticosterone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material


ID: 1609

chemical graph of compound 1609



InChIKey: OMICQBVLCVRFGN-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 77793
synonyms found at PubChem are:
4'-Methoxyflavone, 4143-74-2, 2-(4-methoxyphenyl)-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-, 2-(4-methoxyphenyl)chromen-4-one, 4-Methoxy Flavone, 2-(4-Methoxy-phenyl)-chromen-4-one, CHEMBL16312, OMICQBVLCVRFGN-UHFFFAOYSA-N, 2-(4-methoxyphenyl)-4h-benzopyran-4-one, F0400-0028, SR-01000471678, 4' methoxyflavone, 2-(4-Methoxyphenyl)-4-benzopyrone, 4''-methoxyflavone, EINECS 223-968-8, 4' - Methoxyflavone, Flavone, 4'-methoxy, Spectrum_000114, AC1L2TTZ, AC1Q6AJP, Spectrum2_000774, Spectrum3_001269, Spectrum4_001629, Spectrum5_000417, CBMicro_029575, ChemDiv2_004185, Cambridge id 5324654, CBiol_000291, Oprea1_031095, Oprea1_274709, BSPBio_002838, KBioGR_002037, KBioSS_000554, SPECTRUM240958, cid_77793, MLS000863607, BIDD:ER0472, SCHEMBL311931, SPBio_000848, MEGxp0_001873, DTXSID0063319, ACon1_002036, KBio2_000554, KBio2_003122, KBio2_005690, KBio3_002338, ZINC57689, 4l10, CHEBI:114194, MolPort-000-690-080, HMS1380O05, HMS2271I03, 2-(4-methoxyphenyl)-chromen-4-one, BDBM50310189, CCG-40164, ICCB2_000291, AKOS000603631, ACM4143742, MCULE-7737906545, SDCCGMLS-0066544.P001, IDI1_002900, NCGC00095556-01, NCGC00095556-02, NCGC00095556-03, NCGC00178443-01, NCGC00178443-02, 2-(4-methoxy-phenyl)-4H-chromen-4-one, BAS 01121722, SMR000440756, ST097422, ZB002220, BIM-0029447.P001, TR-017607, EU-0042497, FT-0733585, AD-310/30361023, C-57548, SR-01000471678-1, SR-01000471678-3, BRD-K76337122-001-02-9, BRD-K76337122-001-03-7, I14-21784, A63


ID: 1610

chemical graph of compound 1610



InChIKey: OMKDCTIYUUPVEG-UHFFFAOYSA-N
SMILES: C1C(N(CC2=CC=CC=C21)C(=O)C3=CC(=CC=C3)OC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"T Neuberger" "A Singh" "M Miller" "J González" "J Rader" "S Hadida" "KS Straley" "P Negulescu" "V Panchenko" "PD Grootenhuis" "F Van Goor" "J Joubran" "T Knapp" "LR Makings" "JH Stack" "D Cao" "E Olson" "R Tung" "A Hazlewood"


CID is 44399794
synonyms found at PubChem are:
CHEMBL190630, BDBM50164983, 2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-chloro-phenyl)-amide


ID: 1611

chemical graph of compound 1611



InChIKey: OMSFSNSSFZUDDH-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)F)C2=CC(=O)C3=C(O2)C=C(C=C3)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 52427444
synonyms found at PubChem are:
CHEMBL3781749, MolPort-019-855-664, ZINC57312309, AKOS016402901, MCULE-4205315747


ID: 1612

chemical graph of compound 1612



InChIKey: OMUDWXVBZSPFCW-UHFFFAOYSA-N
SMILES: C1=CSC(=C1)C2=NOC(=C2)CCO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 10703010
synonyms found at PubChem are:
3-(2-Thienyl)-5-isoxazoleethanol


ID: 1613

chemical graph of compound 1613



InChIKey: OMYIZCZQILAOGB-BYLXUVCXSA-N
SMILES: CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6420003
synonyms found at PubChem are:
Cefoperazone dihydrate, 113826-44-1, Prestwick_735, AC1O4WHQ, SCHEMBL3758644, CHEMBL1697715, DTXSID70423565, HMS1569A15, HMS2096A15, HMS3713A15, AKOS027326651, CCG-220327, Cefoperazone dihydrate, VETRANAL(TM), analytical standard, Cefoperazone dihydrate, European Pharmacopoeia (EP) Reference Standard, Cefoperazone dihydrate, United States Pharmacopeia (USP) Reference Standard, (6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate


ID: 1614

chemical graph of compound 1614



InChIKey: OMYMRCXOJJZYKE-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 1864
synonyms found at PubChem are:
6-HYDROXYMELATONIN, 2208-41-5, Lopac-H-0627, 6-OH-melatonin, 6-hydroxy melatonin, N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide, 3-(N-Acetylaminoethyl)-6-hydroxy-5-methoxyindole, 6-Hydroxy-N-acetyl-5-methoxytryptamine, 6-OH-MLT, CCRIS 3473, CHEBI:2198, UNII-TV437T5077, TV437T5077, BRN 0483231, ACETAMIDE, N-(2-(6-HYDROXY-5-METHOXYINDOL-3-YL)ETHYL)-, Acetamide, N-[2-(6-hydroxy-5-methoxyindol-3-yl)ethyl]-, N-(2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl)acetamide, Acetamide, N-(2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl)-, Acetamide, N-[2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]-, 6-Hydroxymelatonine, Melatonin,6-Hydroxy, melatonin, 6-Hydroxy, Melatonin, 6-hydroxy-, AC1L1CEL, D0S6SN, Lopac0_000612, MLS000860057, SCHEMBL674970, SCHEMBL674971, CHEMBL127421, GTPL1347, BDBM82509, CTK8F7147, ZINC57344, DTXSID00176577, OMYMRCXOJJZYKE-UHFFFAOYSA-N, HMS2231I10, HMS3261L06, HMS3370G03, Tox21_500612, MFCD00037971, PDSP1_001787, PDSP1_001812, PDSP2_001770, PDSP2_001795, AKOS022663797, CCG-204701, CS-W012672, HY-W011956, LP00612, LS-9709, NCGC00015495-01, NCGC00015495-02, NCGC00015495-03, NCGC00015495-04, NCGC00093987-01, NCGC00093987-02, NCGC00261297-01, SMR000326915, KB-178583, EU-0100612, FT-0669728, C05643, H 0627, H-6490, 5-22-12-00353 (Beilstein Handbook Reference), L024000, SR-01000075901, J-014482, SR-01000075901-1, 0733A77F-D227-41FD-853E-28134CB5AC46, N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide #, Acetamide, N-(2-(6-hydroxy-5-methoxy-1H-indol-3-yl)ethyl)- (9CI)


ID: 1615

chemical graph of compound 1615



InChIKey: ONKUMRGIYFNPJW-KIEAKMPYSA-N
SMILES: CC(=O)O[C@H]1CC[C@@H]2[C@H]3CC[C@]4([C@H]([C@@H]3CCC2=C1)CC[C@]4(C#C)OC(=O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 9270
synonyms found at PubChem are:
ETHYNODIOL DIACETATE, 297-76-7, Continuin, Femulen, Ethinodiol diacetate, Cervicundin, Metrodiol, Luto-metrodiol, Etynodiol Acetate, Metrodiol diacetate, Ovulen, Ovulen 50, Metrulen, Etynodiol di(acetate), Ethynodiol (diacetate), Luteonorm, 19-Nor-17alpha-pregn-4-en-20-yne-3beta,17-diol diacetate, Etynodiol diacetate, 17a-Ethynyl-4-estren-3b,17-diol diacetate, Ethynodiol diacetate [USAN], CCRIS 305, SC 11800, Ethynodiol diacetate [Progestins], UNII-62H10A1236, EINECS 206-044-9, 17-alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate, SC-11800, 3-beta, 17-beta-Diacetoxy-17-alpha-ethynyl-4-oestrene, 17-alpha-Ethynylestr-4-ene-3-beta,17-beta-diol acetate, (3beta,17beta)-17-ethynylestr-4-ene-3,17-diyl diacetate, 17-alpha-Ethynyl-4-estrene-3-beta,17-beta-diol diacetate, CHEBI:31580, Ethynodiol diacetate (JAN/USP), 3-beta,17-beta-Diacetoxy-19-nor-17-alpha-pregn-4-en-20-yne, (3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol diacetate, 17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol diacetate, 17alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate, 17alpha-Ethynylestr-4-ene-3beta,17beta-diol acetate, 3beta, 17beta-Diacetoxy-17alpha-ethynyl-4-oestrene, 17alpha-Ethynyl-4-estrene-3beta,17beta-diol diacetate, [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate, NCGC00166138-01, 3beta,17beta-Diacetoxy-19-nor-17alpha-pregn-4-en-20-yne, 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol diacetate, 17alpha-Ethynyl-19-norandrost-4-ene-3beta,17-beta-diol diacetate, 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3beta,17alpha)-, DSSTox_CID_614, 62H10A1236, DSSTox_RID_75690, DSSTox_GSID_20614, 17alpha-ethynylestr-4-ene-3beta,17beta-diyl diacetate, 19-norpregn-4-en-20-yn-3beta,17alpha-diol, diacetate, Ethynodiol acetate, 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol, diacetate, (3S,8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate, 8080 C. B., Ethynodiol diacetate [USAN:USP], NCGC00186466-01, CAS-297-76-7, AC1L1SPA, Prestwick0_000908, Prestwick1_000908, Prestwick2_000908, Prestwick3_000908, D0R2KY, SCHEMBL40888, BSPBio_000756, MLS000028661, SPBio_002955, BPBio1_000832, GTPL7072, CHEMBL1200624, DTXSID4020614, MolPort-003-941-317, ONKUMRGIYFNPJW-KIEAKMPYSA-N, HMS1570F18, HMS2097F18, HMS3714F18, BCP10923, HY-B1089, ZINC3876023, Tox21_112333, Tox21_112924, (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate, LMST02030124, s3160, AKOS015895252, Tox21_112333_1, CCG-220908, CS-4640, DB00823, EBD2209572, LS-7392, NCGC00166138-02, NCGC00166138-04, NCGC00166138-05, AJ-46479, AK129080, AN-44141, AS-13382, CC-28314, I036, SMR000058858, 8080 C. B, KB-217641, AB00513958, B1508, C12724, D01294, AB00513958_02, 297E767, 3beta,17beta-Diacetoxy-17alpha-ethynyl-4-estrene, A820050, C-21409, SR-01000872687, J-017631, SR-01000872687-1, (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diolDiacetate, Ethynodiol diacetate, United States Pharmacopeia (USP) Reference Standard, [(3S,8R,9S,10R,13S,14S,17R)-17-acetoxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate, [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ethanoate, acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester


ID: 1616

chemical graph of compound 1616



InChIKey: ONOJPUDFIOEGCX-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)O)CNN.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2724402
synonyms found at PubChem are:
3-Hydroxybenzylhydrazine dihydrochloride, 81012-99-9, 3-(hydrazinylmethyl)phenol dihydrochloride, 3-HYDROXYBENZYLHYDRAZINE 2HCL, alpha-Hydrazino-m-cresol dihydrochloride, m-hydroxybenzylhydrazine dihydrochloride, 3-(Hydrazinomethyl)phenol dihydrochloride, 3-hydroxybenzylhydrazine hydrochloride, Phenol, 3-(hydrazinomethyl)-, dihydrochloride, NSD-1015, 3-(hydrazinomethyl)phenol, chloride, chloride, alpha-Hydrazino-m-cresol HCl, EINECS 279-659-3, PubChem14770, alpha-Hydrazino-m-cresol, AC1MC4UT, KSC915G0P, 3-Hydroxybenzylhydrazine DiHCl, SCHEMBL1309761, CHEMBL1256625, CTK8B5307, DTXSID70230852, MolPort-002-498-991, ONOJPUDFIOEGCX-UHFFFAOYSA-N, 3-HYDROXYBENZYLHYDRAZINE HCl, KS-000011DM, ANW-48273, CH-235, MFCD00044695, SBB003436, AKOS015917359, AC-6614, AN-9853, AS06645, CCG-231659, CM14001, MCULE-6653417290, TRA0066053, 3-Hydrazinomethyl-phenol dihydrochloride, 3-Hydroxybenzy lhydrazine dihydrochloride, 3-hydroxybenzyl hydrazine dihydrochloride, NCGC00093975-01, AK-45523, AS-37889, BR-45523, CC-15313, KB-70853, SC-59091, AB0026818, AX8010048, ST2405098, TC-137018, EU-0100597, FT-0641801, ST50825601, W8565, H 9382, S-3136, 012H999, C-10953, SR-01000075407, NSD-1015; alpha-Hydrazino-m-cresol dihydrochloride, S01-0211, SR-01000075407-1, 3-Hydroxybenzylhydrazine dihydrochloride, >=98.0% (HPLC)


ID: 1617

chemical graph of compound 1617



InChIKey: ONWXNHPOAGOMTG-UHFFFAOYSA-N
SMILES: CCCCC1(C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)COC(=O)CCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5362
synonyms found at PubChem are:
suxibuzone, 27470-51-5, Calibene, Suxibuzona, Suxibuzonum, Solurol, Flogos, 4-Hydroxymethylbutazolidine hemisuccinate, Aflogan, Flamilon, Alfide, Suxibuzonum [INN-Latin], AE-17, Suxibuzona [INN-Spanish], UNII-86TDZ5WP2B, 4-Butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedione hydrogen succinate, CHEBI:32173, AE 17, C24H26N2O6, 4-[(4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy]-4-oxobutanoic acid, EINECS 248-477-6, BRN 0904563, 86TDZ5WP2B, 4-((4-Butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid, 4-Butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione hydrogen succinate (ester), Succinic acid, monoester with 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione, NCGC00016799-01, CAS-27470-51-5, DSSTox_CID_1296, 4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione, 3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester), 3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure, DSSTox_RID_76066, DSSTox_GSID_21296, 4-{[(4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methyl]oxy}-4-oxobutanoic acid, Butanedioic acid, mono[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester, SR-01000841241, Suxibuzone [INN:JAN], suxibutazone, Suxibuzon, Suxibuzone [INN:BAN:JAN], Butanedioic acid, mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl) ester, Prestwick_113, Spectrum_000321, Suxibuzone (JAN/INN), AC1Q5VSO, Prestwick0_000658, Prestwick1_000658, Prestwick2_000658, Prestwick3_000658, Spectrum2_000966, Spectrum3_000664, Spectrum4_000433, Spectrum5_001113, Epitope ID:124941, AC1L1K6N, SCHEMBL25810, BSPBio_000695, BSPBio_002327, KBioGR_000786, KBioSS_000801, MLS002153938, DivK1c_000171, SPECTRUM1501157, SPBio_000971, SPBio_002616, BPBio1_000765, CHEMBL1414320, DTXSID6021296, CTK4F9751, HMS500I13, KBio1_000171, KBio2_000801, KBio2_003369, KBio2_005937, KBio3_001547, BRD5826, MolPort-003-666-374, NINDS_000171, ONWXNHPOAGOMTG-UHFFFAOYSA-N, HMS1570C17, HMS1923I17, HMS2097C17, HMS2232E17, HMS3371A12, HMS3714C17, Pharmakon1600-01501157, BRD-5826, HY-B1079, ZINC3875039, Tox21_110615, Tox21_202352, Tox21_302778, CCG-40180, NSC757866, 1,2-Diphenyl-4-n-butyl-4-hydroxymethyl-3,5-dioxopyrazolidine Hemisuccinate, 4-butyl-4-(beta-carboxypropionyloxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione, AKOS024374988, Tox21_110615_1, API0008442, CS-4635, MCULE-6012520847, NSC-757866, ACM27470515, IDI1_000171, NCGC00016799-02, NCGC00016799-03, NCGC00016799-04, NCGC00016799-05, NCGC00016799-06, NCGC00016799-08, NCGC00095261-01, NCGC00095261-02, NCGC00095261-03, NCGC00095261-04, NCGC00256470-01, NCGC00259901-01, CC-34619, SMR001233279, SBI-0051667.P002, LS-147486, AB00052229, FT-0630533, ST51015119, X6836, D01289, AB00052229_08, AB00052229_09, 470S515, C-22340, J-016775, SR-01000841241-2, SR-01000841241-3, BRD-K78815826-001-05-4, BRD-K78815826-001-08-8, Suxibuzone, European Pharmacopoeia (EP) Reference Standard, 4-[(4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxy]-4-oxobutanoic acid, 4-Butyl-4-(.beta.-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione, Butanedioic acid,1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester, 3-{[(4-butyl-3,5-dioxo-1,2-diphenyl-1,2-diazolidin-4-yl)methyl]oxycarbonyl}pro panoic acid, Butanedioic acid, mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl) ester (9CI)


ID: 1618

chemical graph of compound 1618



InChIKey: ONYOTXAYIZRIPJ-UHFFFAOYSA-N
SMILES: C#CCCCCCCCCCCCC1=CC=CO1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6857797
synonyms found at PubChem are:
AVOCADYNOFURAN, SDCCGMLS-0066920.P001, 2-tridec-12-ynylfuran, AC1OAH7T, 2-(trideca-12-ynyl)furan, SPECTRUM1505808, SCHEMBL8158965, 2-(tridec-12-yn-1-yl)furan, CHEMBL1453347, CTK8H8103, CCG-214387, NCGC00095828-01, 24708-33-6


ID: 1619

chemical graph of compound 1619



InChIKey: OOEMZCZWZXHBKW-SCFUHWHPSA-N
SMILES: CC1=CC=CC=C1CNC2=NC=NC3=C2N=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 65710
synonyms found at PubChem are:
Metrifudil, UNII-7K4GKQ4XSE, 7K4GKQ4XSE, 23707-33-7, CHEMBL331382, Y-341, N-[(2-Methylphenyl)methyl]adenosine, TH-322, Metrifudilum, (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[(2-methylphenyl)methylamino]purin-9-yl]oxolane-3,4-diol, Metrifudil [INN], Metrifudilum [INN-Latin], Th 322, NCGC00015640-02, Adenosine analog, 16, Y 341, D0NQ5I, AC1L23SZ, DSSTox_CID_25168, DSSTox_RID_80718, DSSTox_GSID_45168, GTPL426, SCHEMBL472516, n6 -(2-methylbenzyl)adenosine, DTXSID1045168, OOEMZCZWZXHBKW-SCFUHWHPSA-N, ZINC4216929, Tox21_110187, BDBM50080390, CAS-23707-33-7, 6-(o-Methylbenzylamino)-9-beta-D-ribofuranosyl-9H-purine, (2R,3R,4S,5R)-2-(6-(2-methyl-benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol, (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-(2-methyl-benzylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol


ID: 1620

chemical graph of compound 1620



InChIKey: OOSYXMPLIGBCDA-UHFFFAOYSA-N
SMILES: C1CCC(C1)CCCCCCCCCCCCC(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)CCCCCCCCCCCCC4CCCC4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708773
synonyms found at PubChem are:
Chaulmosulfone, UNII-1S50W1WU8T, 1S50W1WU8T, NCGC00095201-01, 473-32-5, Chaulmosulfon, Chaulmosulfona, KBio2_004998, Spectrum_001903, SpecPlus_000773, Spectrum2_001919, Spectrum5_001830, Chaulmosulfone [INN:DCF], AC1O8FO8, DSSTox_CID_25959, DSSTox_RID_81255, DSSTox_GSID_45959, KBioSS_002436, DivK1c_006869, SPECTRUM1600654, SPBio_001918, SCHEMBL2111021, CHEMBL1360594, DTXSID6045959, KBio1_001813, KBio2_002430, KBio2_007566, HMS1922N06, Tox21_111485, CCG-39457, NCGC00095201-02, CAS-473-32-5, SBI-0207014.P001, 4',4'''-Sulfonylbis(cyclopentanetridecananilide), Bis(4-(13-cyclophentyltridecanamido)phenyl)sulfon, SR-01000872760, SR-01000872760-1, 4,4'''-Bis(13-cyclopentyltridecanamido)diphenylsulfon, 13-cyclopentyl-N-[4-[4-(13-cyclopentyltridecanoylamino)phenyl]sulfonylphenyl]tridecanamide


ID: 1621

chemical graph of compound 1621



InChIKey: OOVDEPZODSXAMU-UHFFFAOYSA-N
SMILES: CC(CC1=CC=C(C=C1)O)(C(=O)OC)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957616
synonyms found at PubChem are:
7361-31-1, alpha-Methyl-DL-tyrosine methyl ester hydrochloride, Methyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate hydrochloride, OOVDEPZODSXAMU-UHFFFAOYSA-N, 2-Methyl-4-hydroxy-DL-phenylalanine methyl ester hydrochloride, ACMC-209orj, EU-0100785, MLS002153439, SCHEMBL540244, CHEMBL1255664, CTK8B2253, KS-00000FME, MolPort-000-004-928, alpha-MT methyl ester hydrochloride, Tox21_500785, ANW-36365, MFCD00012606, NSC152035, AKOS015894415, CCG-222089, CS-W014123, LP00785, NSC-152035, DL-.alpha.-Methyltyrosine, hydrochloride, DL-Tyrosine, methyl ester, hydrochloride, NCGC00094122-01, NCGC00261470-01, WLN: QR D1XZ1&VO1 &GH, -R, DS-11406, Methyl DL-|A-methyltyrosine Hydrochloride, SC-21251, SMR001230806, DL-.alpha.-Methyltyrosine methyl ester HCl, TC-125110, Tyrosine, methyl ester, hydrochloride, DL-, FT-0636456, Methyl .alpha.-methyltyrosinate hydrochloride, METHYL ALPHA-METHYL-DL-TYROSINATE HCL, Methyl DL-.alpha.-methyltyrosine hydrochloride, M 3281, M67118, DL-alpha-METHYL-P-TYROSINE METHYLESTER HCL, DL-alpha-methyltyrosine methyl ester hydrochloride, SR-01000075991, DL-.alpha.-Methyltyrosine methyl ester hydrochloride, I04-8931, p-Tyrosine, methyl ester, hydrochloride, (.+-.)-, SR-01000075991-1, (+/-)-|A-Methyl-p-tyrosine Methyl Ester Hydrochloride, alpha-Methyl-D,L-p-tyrosine Methyl Ester Hydrochloride, d,l-.alpha.-Methyl-p-tyrosine methyl ester hydrochloride, DL-.alpha.-Methyl-p-tyrosine hydrochloride methyl ester, DL-.alpha.-Methyl-p-tyrosine methyl ester hydrochloride, DL-.alpha.-Methyl-p-tyrosine methyl ester, hydrochloride, (.+-.)-.alpha.-Methyl-p-tyrosine methyl ester hydrochloride, Methyl 2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionate HCl, Tyrosine, .alpha.-methyl-, methyl ester, hydrochloride (1:1), alpha-Methyl-DL-tyrosine methyl ester hydrochloride, >=98% (HPLC), alpha-Methyl-DL-tyrosine methyl ester hydrochloride, >=98.0% (TLC), MolPort-039-032-982


ID: 1622

chemical graph of compound 1622



InChIKey: OPAKSOWFKIUFNP-UHFFFAOYSA-N
SMILES: CC(C(=O)OC(C)(C)CC1=CC=C(C=C1)Cl)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957454
synonyms found at PubChem are:
Alaproclate hydrochloride, 60719-83-7, Alaproclate HCl, MLS002153522, SMR001230852, SR-01000075538, 1-(4-Chlorophenyl)-2-methylpropan-2-yl 2-aminopropanoate hydrochloride, EU-0100127, MLS002695885, SCHEMBL467429, CHEMBL1256359, CTK8F7629, 60719-82-6 (Parent), Tox21_500127, MFCD00153761, AKOS030573834, CCG-221431, LP00127, NCGC00093618-01, NCGC00260812-01, A-164, SR-01000075538-1, DL -Alanine 2-(4-chlorophenyl)-1,1-dimethylethyl ester, DL-Alanine 2-(4-chlorophenyl)-1,1-dimethylethyl ester, DL-Alanine 2-(4-chlorophenyl)-1,1-dimethylethyl ester hydrochloride, D,L-Alanine, 2-(4-chlorophenyl)-1,1-dimethylethyl ester hydrochloride


ID: 1623

chemical graph of compound 1623



InChIKey: OPUFDNZTKHPZHM-UHFFFAOYSA-N
SMILES: CC(=C)C1=CC2=CC(=C(C=C2O1)O)C(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 119039
synonyms found at PubChem are:
Euparin, 532-48-9, UNII-46YA021ENM, 46YA021ENM, CHEBI:67437, Ethanone, 1-[6-hydroxy-2-(1-methylethenyl)-5-benzofuranyl]-, Ethanone, 1-(6-hydroxy-2-(1-methylethenyl)-5-benzofuranyl)-, Spectrum_000622, SpecPlus_000146, 5-acetyl-6-hydroxy-2-isopropenylbenzofuran, AC1Q5GFC, Spectrum2_000306, Spectrum3_001229, Spectrum4_001441, Spectrum5_000021, AC1L3O3B, BSPBio_002678, KBioGR_001921, KBioSS_001102, SPECTRUM300007, DivK1c_006242, SPBio_000272, CHEMBL503938, SCHEMBL1675976, KBio1_001186, KBio2_001102, KBio2_003670, KBio2_006238, KBio3_002178, 1-(6-Hydroxy-2-(1-methylethenyl)-5-benzofuranyl)ethanone, DTXSID40201256, OPUFDNZTKHPZHM-UHFFFAOYSA-N, ZINC3197734, CCG-38583, AKOS028108491, NCGC00095568-01, NCGC00095568-02, NCGC00095568-03, NCGC00095568-04, SR-05000002456, SR-05000002456-1, BRD-K26383086-001-02-8, BRD-K26383086-001-03-6, 1-(6-Hydroxy-2-(prop-1-en-2-yl)benzofuran-5-yl)ethanone, 1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone, 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone


ID: 1624

chemical graph of compound 1624



InChIKey: OPUYQGBDVLHIPY-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 14791391
synonyms found at PubChem are:
CHEMBL167787, 7-Hydroxy-flavone, 5e, BDBM85570, BDBM50011427, ZINC13820380, 7-hydroxy-2-(4-nitrophenyl)chromen-4-one, 7-Hydroxy-2-(4-nitro-phenyl)-chromen-4-one, 7-Hydroxy-2-(4-nitrophenyl)-4H-4-chromenone, 7-hydroxy-2-(4-nitrophenyl)-4H-chromen-4-one, 7-Hydroxy-2-(4-nitrophenyl)-4H-1-benzopyran-4-one


ID: 1625

chemical graph of compound 1625



InChIKey: OPVPGKGADVGKTG-BQBZGAKWSA-N
SMILES: CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 188803
synonyms found at PubChem are:
Isospaglumic acid, spaglumic acid, NAAG, 3106-85-2, N-Acetyl-Asp-Glu, N-acetylaspartylglutamate, N-Acetyl-L-aspartyl-L-glutamic acid, UNII-1W8M12WXYL, N-Acetylaspartylglutamic acid, 1W8M12WXYL, CHEBI:73688, N-acetyl-L-alpha-aspartyl-L-glutamic acid, (S)-2-((S)-2-Acetamido-3-carboxypropanamido)pentanedioic acid, Isospaglumic acid [INN], N-Acetyl-1-aspartylglutamic acid, (2S)-2-[[(2S)-2-acetamido-4-hydroxy-4-oxobutanoyl]amino]pentanedioic acid, Acido isospaglumico, Acide isospaglumique, Acidum isospaglumicum, SR-01000597665, Ac-Asp-Glu, N-(N-Acetyl-L-alpha-aspartyl)-L-glutamic acid, Spectrum_000399, Tocris-0391, N-acetyl-L-Asp-L-Glu, Prestwick0_001091, Prestwick1_001091, Prestwick2_001091, Spectrum2_001571, Spectrum3_000759, Spectrum4_000873, Spectrum5_001840, D02FCY, [3H]NAAG, AC1L4NI6, BSPBio_002378, BSPBio_003230, KBioGR_001565, KBioSS_000879, DivK1c_000662, SCHEMBL288514, SPECTRUM1503630, SPBio_001502, SPBio_003051, 2-[(2-acetamido-4-hydroxy-4-oxobutanoyl)amino]pentanedioic acid, GTPL1405, CHEMBL1329032, DTXSID3091535, BDBM17658, HMS502B04, KBio1_000662, KBio2_000879, KBio2_003447, KBio2_006015, KBio3_001598, N-acetylaspartylglutamate (NAAG), MolPort-003-666-491, NINDS_000662, OPVPGKGADVGKTG-BQBZGAKWSA-N, HMS1571K04, Pharmakon1600-01503630, ZINC1532510, CCG-38888, MFCD00076652, NSC758468, 113701-65-8 (magnesium salt), AKOS024457865, NSC-758468, SDCCGMLS-0066696.P001, IDI1_000662, n-acetyl-l-|A-aspartyl-l-glutamic acid, NCGC00016651-01, NCGC00016651-02, NCGC00024569-01, NCGC00024569-02, SBI-0052840.P002, HY-100921, CS-0020591, FT-0774474, C12270, AB00053333_02, 106N852, C-18956, SR-01000597665-1, SR-01000597665-2, W-202283, (2S)-2-[(3S)-3-acetamido-3-formamidopropanoic acid]pentanedioic acid


ID: 1626

chemical graph of compound 1626



InChIKey: OPXKTCUYRHXSBK-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)Cl)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 30849
synonyms found at PubChem are:
Ventipulmin, Spiropent, Planipart hydrochloride, Clenbuterol clorhidrato [Spanish], NAB 365, EINECS 244-643-7, 4-Amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzyl alcoholmonohydrochloride, 4-Amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzylalkohol-hydrochlorid [German], Benzyl alcohol, 4-amino-alpha-((tert-butylamino)methyl)-3,5-dichloro-, monohydrochloride, AC1L1KDS, NAB 365Cl, C12H18Cl2N2O.HCl, AKOS024362791, MCULE-4948829381, LS-42628, ST50993889, [2-(4-amino-3,5-dichlorophenyl)-2-hydroxyethyl]-tert-butylazanium chloride, 1-(4-amino-3,5-dichlorophenyl)-2-[(tert-butyl)amino]ethan-1-ol, chloride, Clenbuterol hydrochloride, 21898-19-1, Clenbuterol HCl, Clenbuterol clorhidrato, Clenbuterol (hydrochloride), MLS000069838, CHEBI:31410, SMR000058854, 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol hydrochloride, 4-Amino-alpha-(t-butylaminomethyl)-3,5-dichlorobenzyl alcohol hydrochloride, Q-200872, 4-Amino-alpha-(tert-butylaminomethyl)-3,5-dichlorobenzyl Alcohol Hydrochloride, 4-Amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol hydrochloride, SR-01000721909, Contrasmina, Clenasma, Siropent, 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol;hydrochloride, Spiropent (TN), Prestwick_761, AC1NWAXY, Opera_ID_146, clenbuterol monohydrochloride, C12H19Cl3N2O, MLS001148242, MLS002222258, Clenbuterol Hydrochloride,(S), SCHEMBL123545, SPECTRUM1503917, (+-)-clenbuterol hydrochloride, CHEMBL1330729, CTK8E4829, REGID_for_CID_5702273, Clenbuterol hydrochloride, >=95%, HMS1569E11, Pharmakon1600-01503917, (+-)-clenbuterol monohydrochloride, BCP13609, HY-B1614, KS-00000KG8, AN-794, BG0145, CCG-39893, Clenbuterol hydrochloride (JAN/USP), Clenbuterol hydrochloride [USP:JAN], NSC758633, AKOS007930709, AM84776, API0002047, CS-6917, NSC-758633, OR70179, NCGC00095982-01, AC-11159, AS-12537, LS-30603, AB0012101, TL8001813, TR-010267, FT-0602363, VU0244438-4, D01360, W-2467, C-45682, SR-01000721909-4, SR-01000721909-5, 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino), 1-(4-amino-3,5-dichloro-phenyl)-2-(tert-butylamino)ethanol hydrochloride, 4-Amino-|A-(t-butylaminomethyl)-3,5-dichlorobenzyl alcohol hydrochloride, Clenbuterol Hydrochloride 1.0 mg/ml in Dimethyl Sulfoxide (as free base), Clenbuterol hydrochloride, European Pharmacopoeia (EP) Reference Standard, (|AR)-4-Amino-3,5-dichloro-|A-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol, 4-amino-3,5-dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol hydrochloride, 4-amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol monohydrochloride, 4-Amino-alpha-((tert-butylamino)methyl)-3,5-dichlorobenzylalkohol-hydrochlorid, Clenbuterol hydrochloride, United States Pharmacopeia (USP) Reference Standard, 4-amino-3,5-dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol monohydrochloride, 53144-57-3, AKOS015896187, I06-1572


ID: 1627

chemical graph of compound 1627



InChIKey: OPXLLQIJSORQAM-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4030
synonyms found at PubChem are:
mebendazole, 31431-39-7, Vermox, Telmin, Mebenvet, Pantelmin, Vermirax, Mebenoazole, Ovitelmin, Bantenol, Mebutar, Lomper, MBDZ, Besantin, Vermicidin, Verpanyl, Noverme, Mebendazol, Mebendazolum, Sufil, Versid, Methyl (5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate, Mebex, Equivurm Plus, Methyl 5-benzoyl-2-benzimidazolecarbamate, Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester, Methyl 5-benzoyl-2-benzimidazolylcarbamate, Mebendazol [INN-Spanish], Mebendazolum [INN-Latin], Vermox (TN), R 17635, Methyl 5-benzoyl benzimidazole-2-carbamate, (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester, 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, CCRIS 4479, methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate, R 17,635, Mebendazole(USAN), NSC 184849, UNII-81G6I5V05I, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate, HSDB 3232, 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester, Mebendazole [USAN:INN:BAN:JAN], Mebendazole (JAN/USP), EINECS 250-635-4, Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate, CHEMBL685, methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate, MEBENDAZOLE, 99%, N-2 (5-Benzoyl-benzimidazole) carbamate de methyle, N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle, Mebendazole (JAN/USP/INN), CHEBI:6704, Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester, N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French], N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French], Methyl 6-benzoyl-1H-benzimidazol-2-ylcarbamate, R17635, 81G6I5V05I, 5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester, NSC184849, methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate, NCGC00016806-01, (5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester, CPD000036734, 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI), CAS-31431-39-7, DSSTox_CID_20682, DSSTox_RID_79538, DSSTox_GSID_40682, R-17635, methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate, (5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester, Banworm, Madicure, Mebendan, Surfont, Vermicol, Vermidil, Wormkuur, Emverm, Sqworm, Vermin, Anti Worm, Anti-Worm, Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI), Pripsen Mebendazole, SMR000036734, SR-01000003109, Boots Threadworm Treatment, Mebatreat, Equivurmp Plus, Mebendazole,(S), Prestwick_310, Pripsen (TN), Antiox (TN), Mebendazole [USAN:USP:INN:BAN:JAN], Ovex (TN), Spectrum_001298, Prestwick0_000217, Prestwick1_000217, Prestwick2_000217, Prestwick3_000217, Spectrum2_001401, Spectrum3_001439, Spectrum4_000416, Spectrum5_001381, SSL Brand of Mebendazole, Diba Brand of Mebendazole, Boots Brand of Mebendazole, D0J1MI, Elfar Brand of Mebendazole, Probes1_000013, Probes2_000149, AC1Q44DR, Cambridge id 5250893, Esteve Brand of Mebendazole, Pfizer Brand of Mebendazole, TimTec1_000869, Janssen Brand of Mebendazole, Norgine Brand of Mebendazole, Streger Brand of Mebendazole, Oprea1_278237, Oprea1_768530, SCHEMBL15860, BSPBio_000233, BSPBio_003178, CBDivE_010559, KBioGR_000712, KBioSS_001778, MLS000028491, MLS006011879, BIDD:GT0087, Degort's Brand of Mebendazole, DivK1c_000751, SPECTRUM1501110, SPBio_001442, SPBio_002154, Taxandria Brand of Mebendazole, AC1L1H98, Ardeypharm Brand of Mebendazole, BPBio1_000257, Leidapharm Brand of Mebendazole, DTXSID4040682, CTK6J2930, CTK8B6803, HMS502F13, KBio1_000751, KBio2_001778, KBio2_004346, KBio2_006914, KBio3_002398, Tedec Meiji Brand of Mebendazole, Healthypharm Brand of Mebendazole, MolPort-000-765-625, MolPort-001-889-615, NINDS_000751, OPXLLQIJSORQAM-UHFFFAOYSA-N, HMS1536H11, HMS1568L15, HMS1921F03, HMS2090B03, HMS2092B15, HMS2095L15, HMS3259B11, HMS3604N11, HMS3712L15, N-(6-benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester, Pharmakon1600-01501110, ZINC121541, EBD12117, KS-00000F1I, Tox21_110620, Abello Farmacia Brand of Mebendazole, ANW-54402, BBL008298, BDBM50180753, CCG-39628, MFCD00057872, MMV003152, NSC757838, s4610, SBB057003, STK093862, AKOS000539066, AKOS015896232, Tox21_110620_1, CS-3974, DB00643, MCULE-4133611535, NC00639, NE41992, NSC-184849, NSC-757838, RTR-013370, IDI1_000751, NCGC00016806-02, NCGC00016806-03, NCGC00016806-04, NCGC00016806-05, NCGC00016806-06, NCGC00016806-07, NCGC00016806-08, NCGC00016806-09, NCGC00016806-10, NCGC00016806-12, NCGC00016806-13, NCGC00021698-03, NCGC00021698-04, NCGC00021698-05, NCGC00021698-06, NCGC00021698-07, AC-12064, AJ-11767, AS-12272, BAS 00341140, HY-17595, LS-48951, Methyl5-benzoyl benzimidazole-2-carbamate, SAM002548959, SAM002589942, ST011967, SBI-0051641.P002, AB1009303, TL8002405, TR-013370, AB00052203, FT-0628179, FT-0628180, M2273, ST24047541, EN300-50844, D00368, W-6804, AB00052203-09, AB00052203_10, Mebendazole, VETRANAL(TM), analytical standard, Methyl [5-(Benzoyl)benzimidazol-2-yl]carbamate, 431M397, A820852, AG-205/04588045, Mebendazole, analytical standard, >=98% (HPLC), Methyl (6-benzoyl-1H-benzimidazol-2-yl)carbamate, I06-2075, methyl 5-benzoyl-1H-benzo[d]imidazol-2-ylcarbamate, SR-01000003109-2, SR-01000003109-3, W-106901, BRD-K77987382-001-01-7, BRD-K77987382-001-06-6, BRD-K77987382-001-08-2, Methyl(5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate, methyl N-(5-benzoyl-1H-1,3-benzimidazol-2-yl)carbamate, Z234895185, 5-benzoyl-1H-benzimidazol-2-yl carbamic acid methyl ester, Mebendazole, European Pharmacopoeia (EP) Reference Standard, methoxy-N-[5-(phenylcarbonyl)benzimidazol-2-yl]carboxamide, methoxy-N-[6-(phenylcarbonyl)benzimidazol-2-yl]carboxamide, methyl N-[6-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate, (5-benzoyl-1(3)H-benzoimidazol-2-yl)-carbamic acid methyl ester;, Mebendazole, United States Pharmacopeia (USP) Reference Standard, Mebendazole for system suitability, European Pharmacopoeia (EP) Reference Standard, Mebendazole Polymorph C, United States Pharmacopeia (USP) Reference Standard, 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester; Mebendazol; Methyl N-(5-benzoyl-1Hbenzimidazol-2-yl)carbamate


ID: 1628

chemical graph of compound 1628



InChIKey: OPZOJWHOZRKYQX-UHFFFAOYSA-N
SMILES: C1=C(ONC1=O)CN.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 205536
synonyms found at PubChem are:
Muscimol hydrobromide, 18174-72-6, Agarin hydrobromide, 5-(Aminomethyl)-3(2H)-isoxazolone hydrobromide, 5-Aminomethyl-3-hydroxyisoxazole hydrobromide, 3(2H)-Isoxazolone, 5-(aminomethyl)-, monohydrobromide, 5-(Aminomethyl)-3-isoxazolol monohydrobromide, 5-Aminomethyl-3-isoxyzole hydrobromide, 5-(Aminomethyl)-3-isoxazolol hydrobromide, 3-Hydroxy-5-aminomethylisoxazole hydrobromide, SR-01000075619, AC1L4EVM, 3-Isoxazolol, 5-(aminomethyl)-, monohydrobromide, MLS002153422, SCHEMBL352714, 3-Isoxazolol, 5-(aminomethyl)-, monohydrobromide (8CI), CHEMBL1256363, SCHEMBL18983675, CTK8G1210, AOB5909, DTXSID40171182, BCP02327, Tox21_500591, MFCD00055184, NSC304080, 5-Aminomethyl-3-hydroxyisoazole, HBr, AKOS028109535, CCG-221895, LP00591, MB00477, NSC-304080, ACM18174726, NCGC00093970-01, NCGC00261276-01, LS-86778, SMR001230797, EU-0100591, FT-0672559, G-019, Muscimol hydrobromide, >=98% (HPLC), solid, 5-(aminomethyl)-1,2-oxazol-3-one hydrobromide, 5-(AMINOMETHYL)-3-ISOXAZOLE HYDROBROMIDE, 5-(AMINOMETHYL)ISOXAZOL-3-OL HYDROBROMIDE, J-011622, SR-01000075619-1, 3(2H)-Isoxazolone,5-(aminomethyl)-,hydrobromide(1:1)


ID: 1629

chemical graph of compound 1629



InChIKey: OQEBIHBLFRADNM-UOWFLXDJSA-N
SMILES: C1[C@H]([C@@H]([C@H](N1)CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 451991
synonyms found at PubChem are:
1,4-dideoxy-1,4-imino-d-arabinitol, imino-D-arabinitol, CHEMBL80254, 3,4-Pyrrolidinediol, 2-(hydroxymethyl-14C)-, (2R,3R,4R)-, 1,4-dideoxy-1,4-imino-D-arabinito, 259140-24-4, (2R,3R,4R)-2-(hydroxymethyl)pyrrolidine-3,4-diol, (2R,3R,4R)-2-Hydroxymethyl-pyrrolidine-3,4-diol, AC1L9PZY, 100937-52-8, D0GS0O, DAB-1, Lopac0_000366, MLS002153179, SCHEMBL143519, DTXSID10180589, OQEBIHBLFRADNM-UOWFLXDJSA-N, HMS2233K17, ZINC1492250, 1,4-Dideoxy-1,4-imino-arabinitol, BDBM50031485, AKOS006343749, CCG-204461, NCGC00162133-01, NCGC00162133-02, SMR001230671, W-200639, (2R,3R,4R)- 2-hydroxymethyl-pyrrolidine-3,4-diol, (2R,3R,4R)-2-(hydroxymethyl)-3,4-Pyrrolidinediol, (2R,3R,4R)-3,4-dihydroxy-2-hydroxymethylpyrrolidine, 1AB


ID: 1630

chemical graph of compound 1630



InChIKey: OQMUOVSEPOBWMK-BWLMZZBKSA-N
SMILES: C[C@@]12CC[C@@H]3[C@]4(C=CC(=O)C(C4=C(C(=O)[C@]3([C@@]15[C@H](O5)C[C@H]2C6=COC=C6)C)O)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 21596358
synonyms found at PubChem are:
Cedrelone, 1254-85-9, (1S,2aR,3aR,3bR,9aR,9bR,11aS)-1-(Furan-3-yl)-5-hydroxy-3b,6,6,9a,11a-pentamethyl-2,2a,6,9a,9b,10,11,11a-octahydronaphtho[1',2':6,7]indeno[1,7a-b]oxirene-4,7(1H,3bH)-dione, SCHEMBL887112, CHEMBL2269927, MolPort-003-804-142, ZINC19795890, 14,15:21,23-Diepoxy-6-hydroxy-4,4,8-trimethyl-24-norchola-1,5,20,22-tetraene-3,7-dione (13alpha,14beta,15beta,17beta)-, 24-Norchola-1,5,20,22-tetraene-3,7-dione, 14,15:21,23-diepoxy-6-hydroxy-4,4,8-trimethyl-, (13alpha,14beta,15beta,17beta)-, W2562


ID: 1631

chemical graph of compound 1631



InChIKey: OQZQSRICUOWBLW-UHFFFAOYSA-N
SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957589
synonyms found at PubChem are:
LY-294,002 hydrochloride, 934389-88-5, LY 294002 HYDROCHLORIDE, LY-294002 hydrochloride, 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride, SR-01000076245, EU-0100710, BIFK0049, SCHEMBL5078472, CHEMBL1398499, CTK8F0293, AOB4477, DTXSID50474691, MolPort-003-958-299, LY 294002, Hydrochloride Salt, BCP17476, EX-A1710, Tox21_500710, ABP000083, AKOS024456404, CCG-222014, LP00710, NCGC00094060-01, NCGC00094060-02, NCGC00261395-01, 2-Morpholin-4-yl-8-phenyl-chromen-4-one, RT-013621, KS-00001829, L 9908, 389L885, CU-00000000012-1, SR-01000076245-1, SR-01000076245-3, 2-morpholin-4-yl-8-phenylchromen-4-one,hydrochloride, 2-(4-Morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one hydrochloride


ID: 1632

chemical graph of compound 1632



InChIKey: ORDAZKGHSNRHTD-UXHICEINSA-N
SMILES: CC1(C=CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 107935
synonyms found at PubChem are:
Deguelin, 522-17-8, (-)-cis-deguelin, (-)-Deguelin, DEGUELIN(-), UNII-K5Z93K66IE, CHEBI:4357, K5Z93K66IE, (-)-Deguelin, Mundulea sericea, ORDAZKGHSNRHTD-UXHICEINSA-N, (7as,13as)-13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3h-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7ah)-one, SR-01000597503, CCRIS 8104, Deguelin/, 3H-Bis(1)benzopyrano, Spectrum_001044, Tocris-1770, AC1Q6KOR, Spectrum2_000298, Spectrum3_001122, Spectrum4_001965, Spectrum5_001852, 3H-Bis(1), SCHEMBL73183, BSPBio_002583, KBioGR_002434, KBioSS_001524, SPECTRUM201138, (7as,13as)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3h-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7ah)-on, MLS006010295, SPBio_000236, AC1L330K, CHEMBL393417, KBio2_001524, KBio2_004092, KBio2_006660, KBio3_002083, DTXSID10200231, MolPort-003-665-481, HMS1923A05, HMS3268E12, 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-, (7aS,13aS)-, 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-, (7aS-cis)-, ZINC3978987, 1702AH, ABP000411, CCG-39856, LMPK12060019, MFCD01740600, s8132, AKOS024456769, ACN-053693, BCP9000596, CS-1802, SDCCGMLS-0066380.P001, NCGC00025288-01, NCGC00025288-02, NCGC00025288-03, (-)-Deguelin, >98% (HPLC), powder, 4CN-1289, AN-16861, HY-13425, SMR004701363, (3,4-b:6',5'-e)pyran-7(7aH)-one, C10417, benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, SR-01000597503-1, SR-01000597503-3, SR-01000597503-4, BRD-K61401890-001-02-0, BRD-K61401890-001-03-8, BRD-K61401890-001-04-6, 13,13a-dihydro- 9,10-dimethoxy-3,3-dimethyl-, (7aS-cis)-, 13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-, (7aS,13aS)-, (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6 inverted exclamation marka,5 inverted exclamation marka-e]pyran-7(7aH)-one, (7aS,13aS)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one, 13,13aS-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-[1]benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aS)-one, 3H-[1]Benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aH)-one, 13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-, (7aS,13aS)-


ID: 1633

chemical graph of compound 1633



InChIKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N
SMILES: C1=CC(=CC2=C1C=CC(=O)O2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5281426
synonyms found at PubChem are:
7-hydroxycoumarin, Umbelliferone, 93-35-6, 7-Hydroxy-2H-chromen-2-one, Hydrangin, Skimmetin, 7-hydroxycoumarine, 7-Oxycoumarin, Hydrangine, Skimmetine, Umbelliferon, 2H-1-Benzopyran-2-one, 7-hydroxy-, 7-Hydroxy-2H-1-benzopyran-2-one, Coumarin, 7-hydroxy-, beta-Umbelliferone, 7-hydroxychromen-2-one, 7 HC, UNII-60Z60NTL4G, 7-hydroxy-coumarin, NSC 19790, CCRIS 3591, NSC19790, EINECS 202-240-3, 7H-1-Benzopyran-7-one, 2-hydroxy-, BRN 0127683, CHEMBL51628, AI3-38054, 60Z60NTL4G, 7-HC, 7-hydroxy-1-benzopyran-2-one, CHEBI:27510, ORHBXUUXSCNDEV-UHFFFAOYSA-N, 7-oxidanylchromen-2-one, 32922-68-2, 7-hydroxycumarin, hydranginn, skimmetinn, 7-hydroxycoumarin, 14C-labeled, 7-hydroxycournarin, P450 (CYP) metabolite|||Phase I metabolite of coumarin (CYP2A6), 7-hydroxy coumarin, beta -umbelliferone, 07L, .beta.-Umbelliferone, Umbelliferone, 99%, AC1NQYGB, PubChem10607, 7-Hydroxy-2-chromenone, Coumarin derivative, 3a, Spectrum2_001962, Spectrum3_000751, 7-hydroxy-chromen-2-one, 7-hydroxycoumarin sulphate, D02JEZ, D04QCJ, 7-Hydroxy Coumarin ,(S), BIDD:PXR0126, SCHEMBL22018, BSPBio_002362, SPECTRUM231084, 5-18-01-00386 (Beilstein Handbook Reference), KSC492S2J, MLS002207035, BIDD:ER0671, SPBio_002083, MEGxp0_000814, DTXSID5052626, ACon1_000219, CTK1B2071, CTK3J2924, KBio3_001582, KS-00000JRX, ZINC58111, 7-Hydroxy-2H-chromen-2-one #, 7-hydroxycoumarin (umbelliferone), 7-Hydroxycoumarin, 98% 25g, MolPort-000-718-609, Umbelliferone (7-Hydroxycoumarin), Umbelliferone, analytical standard, HMS1607M21, HMS2271N09, 2-Hydroxy-7H-1-benzopyran-7-one, ALBB-021296, CS-D1186, HY-N0573, STR04824, ANW-40027, BBL027620, BDBM50174558, CCG-39436, MFCD00006878, NSC-19790, STK331042, Umbelliferone (Hydrangin, Skimmetin), AKOS000120867, AKOS030559697, MCULE-5007617058, NSC-019790, RP22488, RTR-029236, SDCCGMLS-0066941.P001, TRA0061167, NCGC00095801-01, NCGC00095801-02, NCGC00095801-03, NCGC00178691-01, NCGC00178691-02, 4CN-0727, AC-18399, AJ-09810, AN-24261, BR-26455, CJ-00488, KB-74173, LS-55209, NCI60_001646, SC-16986, SMR000112324, ZB002318, AB0011194, AB1001268, DB-014673, TL8005916, TR-029236, BB 0218364, FT-0621430, N2282, ST24024530, ST50308216, Umbelliferone, Vetec(TM) reagent grade, 98%, 1957-EP2272832A1, C09315, M-2996, U-3000, 12293-EP2272972A1, 12293-EP2272973A1, 12293-EP2277872A1, 12293-EP2298312A1, 12293-EP2316974A1, 30511-EP2284170A1, 30511-EP2311835A1, A801734, A844525, I14-0013, BRD-K87991767-001-02-0, BRD-K87991767-001-03-8, Z57150899, F0722-0129, 7-Hydroxycoumarin; Umbelliferone; 7-Hydroxy-2H-1-benzopyran-2-one, Umbelliferone, suitable for fluorescence indicator, >=98.0% (HPLC), InChI=1/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10


ID: 1634

chemical graph of compound 1634



InChIKey: ORNBQBCIOKFOEO-QGVNFLHTSA-N
SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 8955
synonyms found at PubChem are:
pregnenolone, 145-13-1, 3beta-Hydroxypregn-5-en-20-one, Arthenolone, Skinostelon, Enelone, Pregnetan, Pregneton, Pregnolon, Prenolon, Regnosone, Bina-Skin, Natolone, 5-Pregnen-3beta-ol-20-one, delta5-Pregnenolone, 5-Pregnen-3-beta-ol-20-one, 5-Pregnenolone, Pregnenolone [INN:BAN], 3-beta-Hydroxypregn-5-en-20-one, NSC 1616, Pregnenolonum [INN-Latin], Pregnenolona [INN-Spanish], (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE, Prestwick_859, UNII-73R90F7MQ8, 3beta-Hydroxy-5-pregnen-20-one, Pregn-5-en-20-one, 3-hydroxy-, (3beta)-, Prestwick3_000546, EINECS 205-647-4, Pregnenolone (JAN/INN), Pregn-5-ene-3beta-ol-20-one, CHEBI:16581, ORNBQBCIOKFOEO-QGVNFLHTSA-N, Pregn-5-en-20-one, 3-hydroxy-, (3-beta)-, 73R90F7MQ8, Pregn-5-en-20-one, 3beta-hydroxy-, 1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone, Pregn-5-en-20-one, 3-beta-hydroxy-, Pregn-5-en-20-one, 3-hydroxy-, (3b)-, DSSTox_CID_16541, DSSTox_RID_79287, DSSTox_GSID_36541, 5-Pregnen-3beta;-ol-20-one, Pregnenolona, Pregnenolonum, PLO, SMR000112161, .DELTA.5-Pregnenolone, Pregnenolone (3beta-Hydroxypregn-5-en-20-one), SR-05000002128, 5-Pregnen-3.beta.-ol-20-one, delta5-Pregnen-3beta-ol-20-one, Pregnolone, 3.beta.-Hydroxypregn-5-en-20-one, NCGC00163125-02, Pregn-5-en-20-one, 3.beta.-hydroxy-, CAS-145-13-1, Prestwick0_000546, Prestwick1_000546, Prestwick2_000546, Spectrum5_002057, bmse000476, D0B4RU, AC1L1S0M, Pregnenolone (schizophrenia), BIDD:PXR0019, BSPBio_000591, MLS002153868, MLS002207138, SCHEMBL129572, SPBio_002512, 3b-Hydroxy-5-pregnen-20-one, BPBio1_000651, CHEMBL253363, GTPL2376, Pregn-5-en-3beta-ol-20-one, DTXSID1036541, MolPort-002-506-906, 3beta-Hydroxy-5-pregnene-20-one, 3beta-hydroxypregn-5-ene-20-one, HMS1569N13, HMS2090J15, HMS2096N13, HMS2268A04, HMS3713N13, Delta5-Pregnene-3beta-ol-20-one, 1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone, BCP23361, HY-B0151, ZINC3861150, Tox21_112011, Tox21_302141, BDBM50375319, CMC_13393, LMST02030088, MFCD00003628, Pregnenolone (progesterone precursor), s1914, 3beta-Hydroxy-delta5-pregnen-20-one, AKOS015841076, AKOS015895418, Tox21_112011_1, CCG-220546, CS-1970, DB02789, DS-7794, MCULE-4269813571, RL01819, Pregnenolone 0.1 mg/ml in Acetonitrile, .DELTA.5-Pregnen-3.beta.-ol-20-one, 5-Pregnen-3beta-ol-20-one, >=98%, NCGC00163125-03, NCGC00163125-04, NCGC00163125-06, NCGC00255436-01, AC-12806, AN-43964, BC205219, BCP0726000217, Neurosteroid (schizophrenia), Neuroscience, Pregn-5-n-20-ne, 3-ydroxy-, (3)-, Pregnenolone (schizophrenia), Neuroscience, LS-118759, 3-Hydroxypregn-5-en-20-one, (3.beta.)-, 3.beta.-Hydroxy-.DELTA.5-pregnen-20-one, P0786, ST24049035, 3BETA-3-HYDROXY-PREGN-5-EN-20-ONE, Pregn-5-en-20-one, 3beta-hydroxy- (8CI), C01953, D00143, 17beta-[1-Ketoethyl]-Delta5-androsten-3beta-ol, Pregn-5-en-20-one, 3-hydroxy-, (3.beta.)-, 145P131, J-008059, SR-05000002128-4, SR-05000002128-5, BRD-K43880410-001-14-4, 0F6367C4-E1FA-4AEC-9846-7BCC5ADA3417, 1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one, 1-[(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)]ethanone, 1-[(3S,8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-hydroxy-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone, 116907-59-6


ID: 1635

chemical graph of compound 1635



InChIKey: ORRZGUBHBVWWOP-UHFFFAOYSA-N
SMILES: CCC1(CC(=O)NC(=O)C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2310
synonyms found at PubChem are:
bemegride, 64-65-3, 3-Ethyl-3-methylglutarimide, Methetharimide, Megimide, 4-ethyl-4-methylpiperidine-2,6-dione, Bemegrid, Eukraton, Mikedimide, Zentraleptin, Megibal, Megimid, Agipnon, Ahypnon, Antibarbi, Malysol, 3-Methyl-3-ethylglutarimide, 2,6-Piperidinedione, 4-ethyl-4-methyl-, Bemigride, Benegrid, NP13, 2,6-Dioxo-4-methyl-4-ethylpiperidine, 4-Ethyl-4-methyl-2,6-dioxopiperidine, 4-Ethyl-4-methyl-2,6-piperidinedione, 4-Methyl-4-ethyl-2,6-dioxopiperidine, beta-Ethyl-beta-methylglutarimide, Bemegridum [INN-Latin], Glutarimide, 3-ethyl-3-methyl-, Bemegrida [INN-Spanish], UNII-57DQA39DO2, NSC 58187, beta-Methyl-beta-ethylglutarimide, EINECS 200-588-0, 3,3-Methylethylilotarimide, BRN 0116672, AI3-52526, 57DQA39DO2, NP 13, .beta.-Ethyl-.beta.-methylglutarimide, .beta.-Methyl-.beta.-ethylglutarimide, CAS-64-65-3, NCGC00016288-01, Bemegridum, Bemegrida, Ethylmethylglutarimide, Bemegride [INN:BAN:JAN], Bemegride [USP:INN:BAN:JAN], Megibal (TN), Bemegride (JAN/INN), ACMC-1CUJW, Prestwick0_000882, Prestwick1_000882, Prestwick2_000882, Prestwick3_000882, 2, 4-ethyl-4-methyl-, AC1L1DE3, DSSTox_CID_25250, DSSTox_RID_80774, DSSTox_GSID_45250, BSPBio_000664, SCHEMBL601065, SPBio_002883, BPBio1_000732, WLN: T6VMVTJ E2 E1, CHEMBL1214192, DTXSID0045250, CHEBI:92269, CTK8B2099, ORRZGUBHBVWWOP-UHFFFAOYSA-, MolPort-000-917-892, ORRZGUBHBVWWOP-UHFFFAOYSA-N, HMS1570B06, HMS2097B06, HMS3652P09, HMS3714B06, BCP18663, HY-B1326, KS-00000LZ5, NSC58187, ZINC1688939, Tox21_110352, ANW-34926, NSC-58187, s4197, AKOS001108082, CCG-220882, CS-4896, MCULE-7248838464, 3-ethyl-5-methyl-piperidine-2,6-dione, 4-ethyl-4-methyl-piperidine-2,6-dione, NCGC00016288-02, NCGC00179483-01, AJ-29963, CJ-27994, DS-16419, LS-72066, 4-ethyl-4-methylazaperhydroine-2,6-dione, DB-054709, KB-109847, TC-123671, AB00376458, E0284, FT-0631285, ST50308082, D01957, AB00376458_04, Methetharimide<br />|A,|A-methylethylglutarimide, A834846, SR-01000872683, SR-01000872683-1, BRD-K14993104-001-03-4, I14-19969, I14-49893, Z99599698, 3-OO>>u-3-(1/4)x>>uIi paragraph signthorno poundNC degrees ., InChI=1/C8H13NO2/c1-3-8(2)4-6(10)9-7(11)5-8/h3-5H2,1-2H3,(H,9,10,11)


ID: 1636

chemical graph of compound 1636



InChIKey: ORVBSFQTFRBNRP-UHFFFAOYSA-N
SMILES: CC(C)C1=C(C=CC2=C1CCC3C2(CCCC3(C)C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 623264
synonyms found at PubChem are:
Totarol acetate, AC1LDOU3, ORVBSFQTFRBNRP-UHFFFAOYSA-N, 14-Isopropylpodocarpa-8,11,13-trien-13-yl acetate #, Podocarpa-8,11,13-trien-13-ol, 14-isopropyl-, acetate, (4b,8,8-trimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-2-yl) acetate, 2-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, 2-acetate, (4bS,8aS)-, 2-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS)-, 2-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS-trans)-


ID: 1637

chemical graph of compound 1637



InChIKey: OSDLLIBGSJNGJE-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1Cl)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 2723
synonyms found at PubChem are:
4-Chloro-3,5-dimethylphenol, chloroxylenol, 88-04-0, Dettol, PCMX, 4-Chloro-3,5-xylenol, Benzytol, p-Chloro-m-xylenol, 2-Chloro-m-xylenol, 4-Chloro-m-xylenol, Ottasept, Desson, Espadol, Chloro-xylenol, Ottasept Extra, Husept Extra, p-Chloro-3,5-xylenol, Willenol V, 3,5-Dimethyl-4-chlorophenol, Phenol, 4-chloro-3,5-dimethyl-, parachlorometaxylenol, Septiderm-Hydrochloride, Chloroxylenolum, Chlorxylenolum, Cloroxilenol, 2-Chloro-5-hydroxy-m-xylene, Dettol, liquid antiseptic, Nipacide MX, Clorossilenolo, Parametaxylenol, RBA 777, 2-Chloro-5-hydroxy-1,3-dimethylbenzene, 4-Chloro-1-hydroxy-3,5-dimethylbenzene, 3,5-Xylenol, 4-chloro-, Caswell No. 218, Clorossilenolo [DCIT], C8H9ClO, NSC 4971, Cloroxilenol [INN-Spanish], Chloroxylenolum [INN-Latin], UNII-0F32U78V2Q, 4-chloro-3,5-dimethyl-phenol, HSDB 7427, EINECS 201-793-8, 4-Chloro-3, 5-xylenol, EPA Pesticide Chemical Code 086801, BRN 1862539, AI3-08632, CHEBI:34393, Camel, NSC4971, OSDLLIBGSJNGJE-UHFFFAOYSA-N, 0F32U78V2Q, Nipacide PX, NCGC00094614-03, DSSTox_CID_12316, DSSTox_RID_78913, DSSTox_GSID_32316, Vionexus, CAS-88-04-0, Camel (pesticide), Ayrtol, Chloroxylenol [USAN:INN:BAN], chloroxylenol sodium, Chloroxylenol(USAN, Chloroxylenol [USAN:USP:INN:BAN], PubChem19739, Spectrum_000138, 3, 4-chloro-, ACMC-209qqy, m-Xylenol, 4-chloro-, Para-chloro-meta-xylenol, AC1L1EBK, G00014-Watson-Int, Para Chloro Meta Xylenol, Spectrum2_000136, Spectrum3_000344, Spectrum4_000281, Spectrum5_000713, Chloroxylenol (USP/INN), AC1Q2J7T, AC1Q79VA, 4-chloro-3,5dimethylphenol, SCHEMBL34163, BSPBio_002007, KBioGR_000802, KBioSS_000598, p-Chloro-3,5-dimethylphenol, KSC490K5R, MLS000028592, BIDD:ER0218, DivK1c_000801, SPECTRUM1500182, SPBio_000212, WLN: QR DG C1 E1, 3,5-Dimethy-4-Chloro phenol, 3, 5-Dimethyl-4-chlorophenol, CHEMBL398440, ZINC1132, DTXSID0032316, CTK3J0558, HMS502I03, KBio1_000801, KBio2_000598, KBio2_003166, KBio2_005734, KBio3_001227, KS-00000JQO, MolPort-001-770-806, NINDS_000801, HMS1920K19, HMS2091C22, HMS2233N06, HMS3369I18, Para Chloro Meta Xylenol (PCMX), Pharmakon1600-01500182, HY-B1414, NSC-4971, 58962-45-1 (potassium salt), Name: 4-Chloro-3,5-dimethylphenol, Tox21_111305, Tox21_302047, AC-265, ANW-38936, CCG-38943, NSC756683, s4518, STL183324, 4-Chloro-3,5-dimethylphenol, 99%, 54983-54-9 (hydrochloride salt), AKOS009159132, Tox21_111305_1, CS-4912, DB11121, MCULE-8065730786, NE10171, NSC-756683, RP22067, RTR-033329, IDI1_000801, TRA-0206252, NCGC00094614-01, NCGC00094614-02, NCGC00094614-04, NCGC00094614-06, NCGC00255257-01, AJ-07969, AN-15990, BC215707, CJ-00032, H323, KB-72293, SC-22624, SMR000059157, ZB000257, 4-Chloro-3,5-xylenol;p-Chloro-m-xylenol, SBI-0051310.P003, DB-028803, LS-162628, TR-033329, FT-0618059, ST24023473, ST50824606, C14715, D03473, AB00051942_07, SR-01000778359, I01-6302, SR-01000778359-2, 4-Chloro-3,5-dimethylphenol, purum, >=98.0% (T), BRD-K17223896-001-02-7, BRD-K17223896-001-06-8, F0001-2183, Z1235963354, Chloroxylenol, United States Pharmacopeia (USP) Reference Standard, InChI=1/C8H9ClO/c1-5-3-7(10)4-6(2)8(5)9/h3-4,10H,1-2H, Chloroxylenol, Pharmaceutical Secondary Standard; Certified Reference Material


ID: 1638

chemical graph of compound 1638



InChIKey: OSHKWEFWXCCNJR-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 114771
synonyms found at PubChem are:
3',4'-Dichlorobenzamil, dichlorobenzamil, GNF-Pf-1778, 3,4-dichlorobenzamil, 1166-01-4, 3',4'-Dichlorobenzamil hydrochloride, L-594,881, AC1L3FXK, AC1Q3RWN, Lopac-D-8190, D05IGL, 3/',4/'-Dichlorobenzamil, Lopac0_000413, CHEMBL587714, GTPL4597, SCHEMBL10844588, CHEBI:125553, ZINC9226184, MFCD03839362, ACM1166014, CCG-204505, 3,5-diamino-6-chloro-n-[n'-(3,4-dichlorobenzyl)carbamimidoyl]pyrazine-2-carboxamide, NCGC00015373-01, NCGC00015373-02, NCGC00162146-01, BRD-K41049123-001-01-3, 3,5-Diamino-6-chloro-N-(((3,4-dichlorophenyl)amino)iminomethyl)pyrazinecarboxamide, Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-(((3,4-dichlorophenyl)amino)iminomethyl)-, 2-Pyrazinecarboxamide,3,5-diamino-6-chloro-N-[[[(3,4-dichlorophenyl)methyl]amino]iminomethyl]-, 3,5-diamino-6-chloro-N-[(E)-N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide, 3,5-diamino-6-chloro-N-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide


ID: 1639

chemical graph of compound 1639



InChIKey: OSRUSFPMRGDLAG-QMGYSKNISA-N
SMILES: CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6918132
synonyms found at PubChem are:
DORZOLAMIDE HYDROCHLORIDE, Dorzolamide HCl, 130693-82-2, Trusopt, Dorzolomide hydrochloride, Cosopt, Dorzolamide (hydrochloride), UNII-QZO5366EW7, QZO5366EW7, MK-507, DSSTox_CID_25530, DSSTox_RID_80933, DSSTox_GSID_45530, C10H16N2O4S3.HCl, CHEBI:4703, MK 0507, MK-0507, (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride, (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide hydrochloride, Dorzolamide impurity A, L 671152, L-671,152, SR-05000001449, (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide 7,7-dioxide, monohydrochloride, (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride, Dorzolamide HCl salt, Dorzolamide hydrochloride [USAN:USP], NCGC00016977-01, AC1OCF25, CAS-130693-82-2, SCHEMBL41152, MLS002154162, CHEMBL1201162, DTXSID1045530, CTK8E7974, HY-B0109A, KS-00000XJI, MolPort-005-935-141, OSRUSFPMRGDLAG-QMGYSKNISA-N, HMS1571O14, 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S-trans)-, 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 5,6-dihydro-4-(ethylamino)-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S)-, Tox21_110720, ABP001060, s1375, AKOS005146235, AKOS015895951, Dorzolamide hydrochloride (JP17/USP), Tox21_110720_1, AC-5244, API0007146, CCG-221116, CS-1858, KS-1348, RTC-070963, NCGC00179244-03, BC208520, CC-27373, KB-50425, SC-18010, SMR001233461, TC-070963, D4189, FT-0082547, FT-0631133, D00653, J10249, K-4065, 279D961, I06-1271, L-671152, SR-05000001449-3, Dorzolamide hydrochloride, European Pharmacopoeia (EP) Reference Standard, Dorzolamide for system suitability, European Pharmacopoeia (EP) Reference Standard, Dorzolamide hydrochloride, United States Pharmacopeia (USP) Reference Standard, (4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-4HH-thieno(2,3-b)thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride, (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride, (SS,6S)-N-ethyl-6-methyl-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-aminium 7,7-dioxide chloride


ID: 1640

chemical graph of compound 1640



InChIKey: OSVMTWJCGUFAOD-KZQROQTASA-N
SMILES: C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11273
synonyms found at PubChem are:
formestane, 566-48-3, 4-Hydroxyandrostenedione, 4-Hydroxyandrost-4-ene-3,17-dione, Lentaron, CGP-32349, Lentaron(R), 4-OH-A, B, Aromatase inhibitor, 4-Hydroxy-4-androstene-3,17-dione, NSC 282175, 17-dione, 4-OHA, CGP 32349, Formestane [INN:BAN], UNII-PUB9T8T355, CCRIS 7483, ANDROST-4-ENE-3,17-DIONE, 4-HYDROXY-, 4-Hydroxy-delta(sub 4)-androstenedione, BRN 1889793, MLS000028826, MLS002153359, PUB9T8T355, CHEBI:75172, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, SMR000058722, DSSTox_CID_14113, DSSTox_RID_79116, DSSTox_GSID_34113, CAS-566-48-3, 4-Androsten-4-ol-3,17-dione, formestano, formestanum, SaveCream, Lentaron Depot, 4-hydroxyandrostene-3,17-dione, Formestane, solid, NCGC00015070-04, NCGC00164380-02, Lentaron (TN), Formestane (INN), CGP 32 349, Opera_ID_865, AC1Q6OIC, 4-OHAD, D0B6PZ, SCHEMBL25717, MLS001148070, AC1L1X05, Androst-4-ene-3, 4-hydroxy-, DTXSID3034113, 4-hydroxy-Delta4-androstenedione, CTK7H2849, MolPort-003-847-484, OSVMTWJCGUFAOD-KZQROQTASA-N, BDBM225704, CS333, HMS2090I22, HMS2234J06, HMS3715G16, 4-hydroxy-Delta(4)-androstenedione, BCP03066, HY-B0697, ZINC3919580, Tox21_112111, Tox21_113509, Tox21_302286, MFCD00057814, NSC282175, s2208, AKOS015895451, Tox21_112111_1, CCG-221077, CS-2938, DB08905, NSC-282175, NCGC00164380-01, NCGC00255321-01, NCGC00344560-01, AJ-47434, AK115686, AN-15813, CC-28824, LS-19455, NCI60_002316, SC-12219, AB2000542, KB-242363, TR-019862, ST24043795, D07260, AB00572625-07, 566F483, A831133, C-18875, SR-01000721948, Lentaron(R);17-dione;CGP-32349;NSC 282175, SR-01000721948-2, (8R,9S,10R,13S,14S)-10,13-dimethyl-4-oxidanyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione, (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone, 127128-20-5


ID: 1641

chemical graph of compound 1641



InChIKey: OSZCTRWSGNWWBL-UHFFFAOYSA-N
SMILES: C1CN(CCN1)C2=CC(=CC=C2)Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957487
synonyms found at PubChem are:
1-(3-Chlorophenyl)piperazine dihydrochloride, 51639-49-7, UNII-MY02G3EAXQ, 1-(3-chlorophenyl)-piperazine dihydrochloride, MY02G3EAXQ, 1-(3-Chlorophenyl)piperazine HCl, Piperazine, 1-(3-chlorophenyl)-, dihydrochloride, 6640-24-0 (Parent), (3-chlorophenyl)piperazine, chloride, chloride, SR-01000075578, EINECS 257-333-1, m-CPP dihydrochloride, PubChem9402, EU-0100245, SCHEMBL1320253, CHEMBL1256029, CTK6H2718, KS-00000FWV, MolPort-001-770-777, OSZCTRWSGNWWBL-UHFFFAOYSA-N, 1-(3-Chlorophenyl)piperazine diHCl, AC-256, CC0043, MFCD00012764, SBB056106, AKOS015844905, MCULE-2228724572, RP29599, ACM51639497, NCGC00093707-01, AK-35424, AS-10784, BR-35424, CC-02083, SC-04977, AB0008234, DB-024579, KB-146972, LS-111266, TC-060892, 1-(3-chlorophenyl)piperazine;dihydrochloride, AM20060651, FT-0605617, ST24026874, ST50949453, 1-(3-Chlorophenyl)piperazine di hydrochloride, 1-(3-chlorophenyl)piperazine, dihydrochloride, N-(3-chlorophenyl) piperazine dihydrochloride, C 5554, M-1438, C-16938, 1-(M-CHLOROPHENYL)PIPERAZINE DIHYDROCHLORIDE, 1-(M-CHLOROPHENYL)PIPERAZINE-DIHYDROCHLORIDE, I01-2522, SR-01000075578-1, W-105875


ID: 1642

chemical graph of compound 1642



InChIKey: OTCCIMWXFLJLIA-UHFFFAOYSA-N
SMILES: CC(=O)NC(CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 97508
synonyms found at PubChem are:
2545-40-6, N-Acetyl-DL-aspartic acid, 2-Acetamidosuccinic acid, Ac-DL-Asp-OH, DL-Aspartic acid, N-acetyl-, Aspartic acid, N-acetyl (R,S), 2-acetamidosuccinate, 2-acetamidobutanedioic acid, W-107237, SMR000857232, D-Aspartic acid,N-acetyl-, Aspartic acid, N-acetyl-, DL-, Prestwick_712, EINECS 219-827-5, ACMC-20mswo, N-Acetylasparaginsaure, N-Acetyl-L-asparticacid, Aspartic acid,N-acetyl-, N-Acetylaspartic acid #, AC1L3YNL, AC1Q1KFW, AC1Q5KYA, Prestwick0_000415, Prestwick1_000415, Prestwick2_000415, Oprea1_041445, 2-(Acetylamino)succinic acid, MLS001333103, MLS001333104, SCHEMBL163861, SPBio_002309, 2-(acetylamino)butanedioic acid, CHEMBL1162493, CTK4F5791, MolPort-001-833-356, OTCCIMWXFLJLIA-UHFFFAOYSA-N, HMS1569C12, HMS2235G08, HMS3369A07, HMS3373F13, ANW-60646, NSC128610, NSC128611, NSC206260, STK370037, N-Acetyl-DL-aspartic acid, >=95%, AKOS001588124, AKOS016843108, ACM2545406, MCULE-8912395007, NSC-128610, NSC-128611, NSC-206260, VZ36492, MRF-0000765, NCGC00094595-01, AS-17418, BBV-38265551, SC-09375, AX8111984, TC-149391, ST45156778, 545A406, SR-01000390543, I04-8916, I14-2012, SR-01000390543-1


ID: 1643

chemical graph of compound 1643



InChIKey: OTFDPNXIVHBTKW-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC(=O)C1=C(C=CC(=C1)S(=O)(=O)C)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 39855
synonyms found at PubChem are:
EINECS 256-908-4, Tiapride HCl, UNII-25N106WEDO, 25N106WEDO, Benzamide, N-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-, monohydrochloride, N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulphonyl)benzamide monohydrochloride, N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide hydrochloride, diethyl-[2-[(2-methoxy-5-methylsulfonylbenzoyl)amino]ethyl]azanium chloride, AC1L22LR, Tiapride hydrochloride [JAN], 51012-32-9 (Parent), LS-26417, AC1LCWBG, AKOS026750077, N-(2-diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide; hydron; chloride, Tiapride hydrochloride, 51012-33-0, Tiapride (hydrochloride), MLS000069678, SMR000058514, N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-o-anisamide hydrochloride, DSSTox_CID_25210, DSSTox_RID_80753, DSSTox_GSID_45210, SR-01000000232, NCGC00015996-02, CAS-51012-33-0, Gramalil, N-(2-[Diethylamino]ethyl)-5-(methylsulfonyl)-o-anisamide hydrochloride, Gramalil (TN), Prestwick_580, N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide Hydrochloride, Opera_ID_408, AC1NWAV7, Tiapride Hydrochloride,(S), C15H25ClN2O4S, MLS001076118, SCHEMBL355315, SPECTRUM1503086, Tiapride hydrochloride (JP17), CHEMBL1256772, DTXSID4045210, CHEBI:32220, MolPort-003-666-439, OTFDPNXIVHBTKW-UHFFFAOYSA-N, HMS1568L13, HMS1922E05, Pharmakon1600-01503086, BCP13379, HY-B1196, Tox21_110276, Tox21_501124, CCG-39299, MFCD00133861, NSC758225, AKOS015891372, Tox21_110276_1, AB03720, API0004408, CS-4804, HS-0005, LP01124, NSC-758225, NCGC00015996-10, NCGC00094392-01, NCGC00094392-02, NCGC00094392-03, NCGC00094392-04, NCGC00094392-05, NCGC00261809-01, AN-41313, EU-0101124, FT-0630638, T3600, V0289, D01522, T 0410, I01-9655, SR-01000000232-2, SR-01000000232-6, N-(2-diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide hydrochloride, N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide,hydrochloride, N-(2-(DIETHYLAMINO)ETHYL)-2-METHOXY-5-(METHYLSULFONYL)-BENZAMIDE HYDROCHLORIDE, N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonyl-benzamide hydrochloride


ID: 1644

chemical graph of compound 1644



InChIKey: OTIOLMDUPDTDHA-DBHSDMCESA-N
SMILES: CC(C)C(=O)O[C@H]1[C@@H]2CC3=C4CC(=O)O[C@H]([C@@]4(CCC3[C@@](C2=O)([C@H](C1(C)C)CC(=O)OC)C)C)C5=COC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708735
synonyms found at PubChem are:
KBio1_001700, FISSINOLIDE C, SpecPlus_000660, DivK1c_006756


ID: 1645

chemical graph of compound 1645



InChIKey: OTKJDMGTUTTYMP-MSOLQXFVSA-N
SMILES: CCCCCCCCCCCCCCC[C@@H]([C@@H](CO)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6603822
synonyms found at PubChem are:
DL-erythro-Dihydrosphingosine, DL-Sphinganine, L-ERYTHRO-DIHYDROSPHINGOSINE, 3102-56-5, (2R,3S)-2-aminooctadecane-1,3-diol, 6036-76-6, NCGC00093867-01, DL-erythro-1,3-Dihydroxy-2-aminooctadecane, Lopac-D-6908, AC1O7G2I, Lopac0_000451, MLS002153314, SCHEMBL7106054, CHEMBL1487948, HMS3261K04, ZINC8034905, Tox21_500451, CCG-204543, LP00451, SPC-103980, NCGC00015362-01, NCGC00015362-02, NCGC00015362-04, NCGC00093867-02, NCGC00093867-03, NCGC00093867-04, NCGC00261136-01, SMR000326929, EU-0100451, D 6908, DL-erythro-Dihydrosphingosine, >=99%, synthetic, SR-01000075827, J-018226, SR-01000075827-1


ID: 1646

chemical graph of compound 1646



InChIKey: OTPSWLRZXRHDNX-UHFFFAOYSA-L
SMILES: C1=CC=[N+](C(=C1)[S-])[O-].C1=CC=[N+](C(=C1)[S-])[O-].[Zn+2]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 26041
synonyms found at PubChem are:
Mercaptopyridine-N-oxide, Zinc Pyrithione Powder, NCGC00091933-01, NCGC00183121-01, DSSTox_CID_6314, DSSTox_RID_78100, C10H8N2O2S2Zn, DSSTox_GSID_26314, Zincpolyanemine, 1-Hydroxypyridine-2-thione zinc, zinc bis(2-thioxopyridin-1(2H)-olate), CAS-13463-41-7, Sebulon Shampoo, Kopthione Powder, Zinci pyrithionum, Zinc pt, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, ZNP bar, Tomicide Z 50, Tomicide ZPT 50, Evafine P 50, Kopthione 50% fps, Caswell No. 923, Kopthione 40% FPS, bis(N-oxopyridine-2-thionato)zinc (II), BC-J, 2C5H4NOS.Zn, Zinc Pyrithione 40% FPD, Zinc 2-pyridinethiol-1-oxide, CCRIS 4894, oC>>ussAa currencyAoI feminine, Zinc pyridine-2-thiol 1-oxide, Zinc Pyrithione 48% suspension, (T-4)-bis(1-hydroxy-2(1H)- pyridinethionato-O,S)zinc, HSDB 4498, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, bis(1-oxidopyridin-2-ylthio)zinc, Bis(2-pyridinethiol-1-oxide)zinc, MolPort-023-220-327, Pyrithione zincique [INN-French], Pyrithionum zincicum [INN-Latin], Piritionato cincico [INN-Spanish], Pyrithione zinc [USAN:INN:BAN], FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, EINECS 236-671-3, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, LS-784, 2-Mercaptopyridine 1-oxide zinc salt, HEAD AND SHOULDERS CONDITIONER, Bis(2-pyridylthio)zinc 1,1'-dioxide, API0004646, DB06815, EPA Pesticide Chemical Code 088002, NSC 290409, NCGC00257089-01, NCGC00259729-01, I976, AI3-62421, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, J10432, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, Q-201649, Mercaptopyridine N-oxide Eth inverted question markNI, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, Zinc, bis(1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2)-, (T-4)-, 2-({[(1-oxidopyridin-1-ium-2-yl)sulfanyl]zincio}sulfanyl)pyridin-1-ium-1-olate, BCP13412, NSC68093


ID: 1647

chemical graph of compound 1647



InChIKey: OTQYGBJVDRBCHC-UHFFFAOYSA-N
SMILES: C1CN=C(N1)NC2=C(C=C(C=C2Cl)N)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 51763
synonyms found at PubChem are:
APRACLONIDINE HYDROCHLORIDE, 73218-79-8, p-Aminoclonidine hydrochloride, Apraclonidine HCl, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride, NC 14 hydrochloride, ALO-2145, Iopidine ophthalmic solution, UNII-D2VW67N38H, 2-(4-Amino-2,6-dichlorophenylimino)imidazolidine hydrochloride, 3,5-Dichloro-4-(2-imidazolidinylidenimino)aniline hydrochloride, Apraclonidine hydrochloride, 2-((4-Amino-2,6-dichlorophenyl)imino)imidazolidine monohydrochloride, CHEBI:2789, D2VW67N38H, NCGC00093552-01, 2,6-Dichloro-N(sup 1)-(2-imidazolidinylidene)-1,4-benzenediamine hydrochloride, 2,6-Dichloro-N(sup 1)-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine monohydrochloride, 2-(4-Amino-2,6-dichloroanilino)-2-imidazoline hydrochloride, 2,6-Dichloro-N(1)-(2-imidazolidinylidene)-1,4-benzenediamine hydrochloride, 1,4-Benzenediamine, 2,6-dichloro-N(sup 1)-2-imidazolidinylidene-, monohydrochloride, 2,6-Dichloro-N(1)-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine monohydrochloride, 1,4-Benzenediamine, 2,6-dichloro-N(sup 1)-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride, SMR000058965, Apraclonidinehydrochloride, AL-02145, Aplonidine HCl, Apraclonidine hydrochloride [USAN], Apraclonidine hydrochloride [USAN:USP], Aplonidine hydrochloride, AC1L1BOD, C9H10Cl2N4.HCl, DSSTox_CID_25749, DSSTox_RID_81093, DSSTox_GSID_45749, SCHEMBL41138, C9H11Cl3N4, MLS000028829, MLS006010230, CHEMBL1200379, DTXSID6045749, CTK8F7806, KS-00000MLM, p-Aminoclonidine Monohydrochloride, MolPort-006-069-427, OTQYGBJVDRBCHC-UHFFFAOYSA-N, Tox21_111207, Tox21_500033, BG0575, p-Aminoclonidine hydrochloride, solid, AKOS022175501, AKOS025401362, Apraclonidine hydrochloride (JAN/USP), AL02145, AN-6532, CCG-221337, DS-7631, LP00033, 2-yl)benzene-1,4-diamine hydrochloride, NCGC00260718-01, AC-12705, AK143283, AL 02145, CC-24163, LS-29586, S311, CAS-73218-79-8, ST2409192, 4CH-016312, EU-0100033, FT-0602878, 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-, A 0779, D01008, 218A798, A837749, C-17735, SR-01000075247, SR-01000075247-1, 2-[(2,6-dichloro-4-aminophenyl)imino]imidazolidine hydrochloride, 2,6-bis(chloranyl)-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride, 2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride, 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine Hydrochloride, 87913-86-8


ID: 1648

chemical graph of compound 1648



InChIKey: OTVAEFIXJLOWRX-NXEZZACHSA-N
SMILES: CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 27200
synonyms found at PubChem are:
thiamphenicol, 15318-45-3, Thiophenicol, Thiamcol, (+)-Thiamphenicol, Raceophenidol, Thiocymetin, Dextrosulphenidol, Thiamphenicolum, D-Thiocymetin, D-Thiophenicol, Thiocymetin (TN), Armai (TN), Tiamfenicolo [DCIT], UNII-FLQ7571NPM, Tiamfenicol [INN-Spanish], Thiamphenicol (Thiophenicol), C12H15Cl2NO5S, Macphenicol, Descocin, Dexawin, Efnicol, Hyrazin, Igralin, Masatirin, Neomyson, Rincrol, Thiamphenicolum [INN-Latin], Urfamicina, Urfamycine, SW 5063, Unaseran-D, EINECS 239-355-3, Thiamphenicol [USAN:INN:BAN:JAN], RACEPHENICOL, NSC 522822, WIN-5063-2, FLQ7571NPM, MLS001332640, D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide, CHEBI:32215, Methylsulfonylchloramphenicol, 2,2-dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R-(R*,R*))-, SMR000857096, DSSTox_CID_1338, D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol, D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol, 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide, DSSTox_RID_76092, DSSTox_GSID_21338, Racefenicolo, Racefenicolum, Thiomycetin, Tiamfenicol, Tiamfenicolo, Vicemycetin, Dextrosulfenidol, 2,2-dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide, Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)-, D-threo-(+), 8065 C.B., Racefenicolo [DCIT], Racephenicol [USAN], SR-05000001829, Racefenicolum [INN-Latin], CCRIS 8588, Thiamphenicol DL-, NCGC00016714-01, Prestwick_885, Racefenicol [INN], CAS-15318-45-3, Spectrum_001428, AC1L1CPJ, Prestwick0_000025, Prestwick1_000025, Prestwick2_000025, Prestwick3_000025, Spectrum2_000856, Spectrum3_001562, Spectrum4_000733, Spectrum5_001617, D03YLZ, AC1Q3GZ9, SCHEMBL34635, BSPBio_000089, BSPBio_003064, KBioGR_001026, KBioSS_001908, cid_27200, MLS001332639, MLS002154177, DivK1c_000842, SPECTRUM1503136, SPBio_000871, SPBio_002010, BPBio1_000099, CHEMBL1236282, DTXSID5021338, Thiamphenicol (JAN/USAN/INN), BDBM58925, HMS502K04, KBio1_000842, KBio2_001908, KBio2_004476, KBio2_007044, KBio3_002564, MolPort-003-666-809, NINDS_000842, OTVAEFIXJLOWRX-NXEZZACHSA-N, Thiamphenicol, analytical standard, HMS1568E11, HMS1922G19, HMS2092L18, HMS2095E11, HMS2232E21, HMS3712E11, Pharmakon1600-01503136, ZINC538440, 3785-14-6, 90-91-5, HY-B0479, Tox21_110577, Tox21_200816, CCG-40309, MFCD00467983, NSC758396, s2583, WIN-50632, AKOS015951269, dl-threo-2-Dichloroacetamido-1-(4-methylsulfonyl-phenyl)-1,3-propanediol, Tox21_110577_1, CS-2593, DB08621, LS-8877, NSC-758396, IDI1_000842, SMP2_000125, NCGC00178319-01, NCGC00178319-02, NCGC00178319-03, NCGC00178319-06, NCGC00178319-07, NCGC00258370-01, (+-)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)-, threo-(+-)-, AS-12501, BC202509, CC-34967, KB-61580, SBI-0051779.P002, AB0012036, AB1009304, FT-0630426, C12853, D01407, J90001, AB00052321_10, AB00052321_11, 318T453, C-20774, SR-05000001829-1, SR-05000001829-3, BRD-K79711234-001-06-8, BRD-K79711234-001-11-8, Thiamphenicol, European Pharmacopoeia (EP) Reference Standard, UNII-283383NO13 component OTVAEFIXJLOWRX-NXEZZACHSA-N, 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-2-(4-mesylphenyl)-1-methylol-ethyl]acetamide, D-threo-2,2-Dichloro-N-(|A-hydroxy-|A-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide, 14786-51-7, 2,2-bis(chloranyl)-N-[(1R,2R)-1-(4-methylsulfonylphenyl)-1,3-bis(oxidanyl)propan-2-yl]ethanamide, 32430-04-9, Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, rel-, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R*,R*)-(+-)-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)-,D-threo-(+), Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, D-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide, TH8


ID: 1649

chemical graph of compound 1649



InChIKey: OUDSBRTVNLOZBN-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5503
synonyms found at PubChem are:
tolazamide, Tolinase, Norglycin, 1156-19-0, Tolanase, Diabewas, Tolazolamide, Tolazamida, Tolazamidum, 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea, N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea, 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide, NCI-C03327, 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea, Tolazamidum [INN-Latin], Tolazamida [INN-Spanish], U 17835, U-17835, CCRIS 591, NSC-70762, Tolamide, UNII-9LT1BRO48Q, Urea, 1-(hexahydroazepin-1-yl)-3-p-tolylsulfonyl-, EINECS 214-588-3, Tolinase (TN), Urea, 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)-, BRN 1323565, HSDB 3192, Tolazamide [USAN:INN:BAN:JAN], NSC 70762, 9LT1BRO48Q, AI3-50826, MLS000028534, CHEBI:9613, C14H21N3O3S, 1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea, N-(((Hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methylbenzenesulfonamide, NSC70762, N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide, Benzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methyl-, Benzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-, 1-(Hexahydro-1H-azepin-1-yl)-3-(p-toluenesulfonyl)urea, N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide, NCGC00016009-10, SMR000058290, CAS-1156-19-0, DSSTox_CID_1358, Benzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methyl-, T 2408, 3-azepan-1-yl-1-(4-methylphenyl)sulfonyl-urea, DSSTox_RID_76105, DSSTox_GSID_21358, 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea, W-109110, 1-(((((4-Methylphenyl)sulfonyl)amino)carbonyl)amino)azepane, N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methylbenzenesulfonamide, N-[[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methylbenzenesulfonamide, Benzenesulfonamide, {N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-}, SR-01000003105, Tolazamid, Ronase, (azaperhydroepinylamino)-N-[(4-methylphenyl)sulfonyl]carboxamide, N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide, Prestwick_865, Tolazamide [USAN:USP:INN:BAN:JAN], Spectrum_001269, AC1L1KHJ, Opera_ID_1740, Prestwick0_000554, Prestwick1_000554, Prestwick2_000554, Prestwick3_000554, Spectrum2_001449, Spectrum3_001473, Spectrum4_000240, Spectrum5_001204, Lopac-T-2408, CHEMBL817, D09FJB, NCIOpen2_008361, CBiol_001918, Lopac0_001195, Oprea1_061180, SCHEMBL34417, BSPBio_000627, BSPBio_001505, BSPBio_003025, KBioGR_000225, KBioGR_000939, KBioSS_000225, KBioSS_001749, 5-20-04-00062 (Beilstein Handbook Reference), MLS001076161, Pharmacia Brand of Tolazamide, DivK1c_000212, SPECTRUM1501201, SPBio_001317, SPBio_002548, BPBio1_000691, GTPL6847, Tolazamide (JP15/USP/INN), Tolazamide (JP17/USP/INN), WLN: T7NTJ AMVMSWR D1, DTXSID3021358, BCBcMAP01_000061, HMS500K14, KBio1_000212, KBio2_000225, KBio2_001749, KBio2_002793, KBio2_004317, KBio2_005361, KBio2_006885, KBio3_000449, KBio3_000450, KBio3_002525, ZINC57512, MolPort-001-826-273, NINDS_000212, OUDSBRTVNLOZBN-UHFFFAOYSA-N, Bio1_000204, Bio1_000693, Bio1_001182, Bio2_000225, Bio2_000705, HMS1361L07, HMS1569P09, HMS1791L07, HMS1921P19, HMS1989L07, HMS2089L10, HMS2092L09, HMS2096P09, HMS2232L21, HMS3259O18, HMS3263P11, HMS3369L04, HMS3402L07, HMS3713P09, Pharmakon1600-01501201, BCP23550, HY-B0920, Tox21_110281, Tox21_201507, Tox21_300416, Tox21_501195, 2761AH, CCG-39178, GP6227, LS-578, MFCD00083504, NSC758149, SBB058190, AKOS015913823, Tox21_110281_1, ACN-053046, API0004439, DB00839, KS-1438, LP01195, MCULE-9265102499, NC00590, NSC-758149, 4-(p-Tolylsulfonyl)-1,1-hexamethylene, IDI1_000212, IDI1_033975, NCGC00016009-01, NCGC00016009-02, NCGC00016009-03, NCGC00016009-04, NCGC00016009-05, NCGC00016009-06, NCGC00016009-07, NCGC00016009-08, NCGC00016009-09, NCGC00016009-11, NCGC00016009-12, NCGC00016009-13, NCGC00016009-14, NCGC00016009-15, NCGC00016009-16, NCGC00016009-17, NCGC00016009-19, NCGC00023701-03, NCGC00023701-04, NCGC00023701-05, NCGC00023701-06, NCGC00023701-07, NCGC00023701-08, NCGC00023701-09, NCGC00023701-10, NCGC00254501-01, NCGC00259058-01, NCGC00261880-01, CPD000058290, SAM002564236, 1-(azepan-1-yl)-3-(p-tolylsulfonyl)urea, SBI-0051162.P003, AB00052247, EU-0101195, FT-0675268, ST51015133, 59866P, D00379, AB00052247-15, AB00052247_16, AB00052247_17, C-55259, 1-(azepan-1-yl)-3-[(4-methylbenzene)sulfonyl]urea, SR-01000003105-2, SR-01000003105-4, SR-01000003105-5, SR-01000003105-8, BRD-K32164935-001-06-8, BRD-K32164935-001-17-5, BRD-K32164935-001-28-2, I14-44488, F2173-1137, 1-[(([(4-Methylphenyl)sulfonyl]amino)carbonyl)amino]azepane #, Tolazamide, United States Pharmacopeia (USP) Reference Standard, Benzenesulfonamide, N-[[(hexahydro-1-azepinyl)amino]carbonyl]-4-methyl-


ID: 1650

chemical graph of compound 1650



InChIKey: OVBPIULPVIDEAO-LBPRGKRZSA-N
SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6037
synonyms found at PubChem are:
folic acid, 59-30-3, Folate, Pteroylglutamic acid, Vitamin M, Folacin, Folacid, PteGlu, Vitamin B9, Folvite, Pteroyl-L-glutamic acid, Vitamin Bc, Acifolic, Cytofol, Incafolic, Folcidin, Folettes, Foliamin, Folicet, Folipac, Folsaure, Millafol, Folbal, Folsan, Folsav, Vitamin Be, Pteroyl-L-monoglutamic acid, Mittafol, Facid, Folan, Pteroylmonoglutamic acid, Antianemia factor, Factor U, Folico (Italy), Folina (Italy), Foldine [France], Acfol (Spain), Pteroylmonoglutamate, Foldine, Folcysteine, Vitamin B11, Folasic (Australia), Folaemin [Netherlands], Nifolin [Denmark], Folcidin (VAN), Kyselina listova [Czech], Mission prenatal, Novofolacid [Canada], Usaf cb-13, Acide folique [INN-French], Acido folico [INN-Spanish], Acidum folicum [INN-Latin], Liver Lactobacillus casei factor, Novofolacid, Folaemin, Folvron, Nifolin, PGA (VAN), Folico, Folina, Folic, Acidum folicum, Acido folico, Kyselina listova, Glutamic acid, pteroyl-, l-, Dosfolat B activ, NSC 3073, Folsaeure, Aspol, Apo-Folic, Pteroyglutamic acid, [3H]folic acid, Serum Folate Level, CCRIS 666, Folicet (TN), Pteroyl-L-glutamate, [3H]-folic acid, Folic acid [INN:BAN:JAN], UNII-935E97BOY8, AI3-26387, HSDB 2002, C19H19N7O6, EINECS 200-419-0, Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L, N-pteroyl-L-glutamic acid, PGA, 4-Pteridinol, 2-amino-6-((p-((1,3-dicarboxypropyl)carbamoyl)anilino)methyl)-, Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, l-, N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, Folic acid [BAN:INN:JAN], L-Glutamic acid, N-(4-((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, CHEBI:27470, OVBPIULPVIDEAO-LBPRGKRZSA-N, 935E97BOY8, (2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid, L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, CAS-59-30-3, PteGlu;Vitamin M;Pteroyl-L-glutamic acid, F0043, DSSTox_CID_2519, FOLATE SODIUM, DSSTox_RID_76606, L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-, N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid, DSSTox_GSID_22519, FOL, Megafol, Neocepri, Acide folique, N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid, N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid, (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid, SMR000471860, Folic acid (TN), 32108-06-8, Acidefolique, Folovit, Pteroylglutamate, YEASTFOLATEPOLYGLUTAMATE, Pteroyglutamicacid, (S)-2-(4-((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methylamino)benzamido)pentanedioic acid, L-Glutamic acid, N-(4-(((2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, N-[4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoyl]-l-glutamic acid, Folic acid [USP:INN:BAN:JAN], NCGC00142391-03, Prestwick_230, Folic Acid,(S), Folic Acid USP/BP, Pteroyl-L-monoglutamate, Spectrum_001381, 2d0k, Folic acid, USP grade, AC1L1LNX, Folic acid, >=97%, Prestwick3_000627, Spectrum2_001459, Spectrum3_000749, Spectrum4_001751, Spectrum5_000602, bmse000299, D08OTA, D09BGR, D0Z0DW, SCHEMBL3876, CHEMBL1622, BSPBio_000594, BSPBio_002338, Folic acid, 96% 25g, KBioGR_002222, KBioSS_001861, MLS001304016, MLS001335861, MLS002548873, BIDD:ER0563, BIDD:GT0641, DivK1c_000494, SPECTRUM1502020, LiverLactobacillus casei factor, SPBio_001357, ARONIS014410, BPBio1_000654, Folic acid, analytical standard, GTPL4562, GTPL4563, DTXSID0022519, Folic acid (JP15/USP/INN), Folic acid (JP17/USP/INN), CTK8G0378, HMS501I16, KBio1_000494, KBio2_001861, KBio2_004429, KBio2_006997, KBio3_001558, BIF0608, MolPort-003-665-625, MolPort-004-285-551, MolPort-008-266-632, MolPort-044-561-726, NINDS_000494, HMS1921D20, HMS2092N17, HMS2096N16, HMS2270L05, HMS3259A05, HMS3713N16, Pharmakon1600-01502020, KS-00000F2X, ZINC8577218, Tox21_111559, Tox21_300127, BDBM50367343, CCG-38869, MFCD00079305, NSC758158, s4605, AKOS000503224, AKOS015895671, AKOS016007919, Tox21_111559_1, DB00158, GS-6860, LS-2157, NC00455, NSC-758158, SDCCGMLS-0066738.P001, 36653-55-1 (mono-potassium salt), ACM32108068, IDI1_000494, SMP2_000137, 6484-89-5 (mono-hydrochloride salt), Folic acid, tested according to Ph.Eur., NCGC00016265-01, NCGC00016265-02, NCGC00016265-03, NCGC00016265-04, NCGC00016265-05, NCGC00016265-08, NCGC00142391-01, NCGC00254203-01, AC-11682, AJ-70570, BC203079, BP-13474, CPD000471860, HY-16637, SAM002264616, SC-20759, SY010866, SBI-0051701.P002, KB-299154, Folic acid, meets USP testing specifications, FT-0600598, FT-0626515, N2075, C00504, D00070, Folic acid, Vetec(TM) reagent grade, >=97%, J10084, Z-4094, 079F305, BRD-K18673820-001-07-2, Folic acid, European Pharmacopoeia (EP) Reference Standard, Folic acid, United States Pharmacopeia (USP) Reference Standard, Folic acid, Pharmaceutical Secondary Standard; Certified Reference Material, N-(4-{[(2-Amino-4-hydroxy-6-pteridinyl)methyl]amino}benzoyl)glutamic acid, N-{p-[(2-amino-4-hydroxypteridin-6-yl)methylamino]benzoyl}glutamic acid, L-glutamic acid, N-[4-[[(2-amino-4,8-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo-yl)-L-glutamic acid, (2S)-2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid, 11096-55-2, 112339-08-9, 33609-88-0, Folic acid, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=97%, InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s


ID: 1651

chemical graph of compound 1651



InChIKey: OVMSOCFBDVBLFW-VHLOTGQHSA-N
SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 65366
synonyms found at PubChem are:
Baccatin III, 27548-93-2, BACCATINE III, NSC 330753, UNII-40K5PZ0K67, CHEBI:32898, 40K5PZ0K67, C31H38O11, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 7,11-Methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha,11alpha,12alpha,12aalpha,12balpha))-, b(2aH)-diyl diacetate, AC1L234D, CHEMBL288043, SCHEMBL3118475, EX-A832, MolPort-003-940-535, OVMSOCFBDVBLFW-VHLOTGQHSA-N, Baccatin III, >=95% (HPLC), ZINC4102268, AKOS024462641, CCG-208344, AS-35071, AB0021839, LS-183707, ST24046003, W1317, C11900, 548B932, Q-100350, 13-O-De[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]paclitaxel (Baccatin III), (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate, [2aR-(2aalpha,4beta,4abeta,6beta,9alpha,11alpha,12alpha,12aalpha,12balpha)]-6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one, 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate


ID: 1652

chemical graph of compound 1652



InChIKey: OVSQVDMCBVZWGM-QSOFNFLRSA-N
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5280804
synonyms found at PubChem are:
Isoquercitrin, Isoquercetin, 482-35-9, Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside, Glucosyl 3-quercetin, Quercetin 3-glucoside, Quercetol 3-glucoside, Quercetin 3-D-glucoside, Quercetin 3-monoglucoside, Quercetol 3-monoglucoside, Isotrifoliin, Quercetin 3-beta-glucoside, Quercetin 3-O-glucoside, quercetin-3-glucoside, CONTIGOSIDE B, Quercetin 3-beta-O-glucoside, Quercetin-3-O-glucopyranoside, UNII-6HN2PC637T, quercetin-3-O-glucoside, quercetin 3-O-beta-D-glucopyranoside, NSC 115918, BRN 0100989, 6HN2PC637T, CHEMBL250450, CHEBI:68352, NSC-407304, Q 5, 3,3',4',5,7-Pentahydroxyflavone 3-beta-glucoside, 2-(3,4-Dihidroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl beta-D-glucopyranoside, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-, Quercetin-3-galactoside, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, SMR000466391, Quercetin 3-beta-D-glucoside, hydroside, CCRIS 9340, Isoquercitrin (6), ACACIA, AC1NQXMB, 3-glucoside isoquercitrin, Quercetin 3--D-glucoside, D04PBH, Quercetin 3-b-D-glucoside, 3-beta-D-Glucosylquercetin, Quercetin 3-glucopyranoside, Quercetin 3- -D-glucoside, Quercetin 3-|A-D-glucoside, 4-18-00-03493 (Beilstein Handbook Reference), MLS000759532, MLS001424096, SCHEMBL181306, BIDF1022, ACon1_002134, cid_5280804, cid_5378597, MolPort-001-740-247, OVSQVDMCBVZWGM-QSOFNFLRSA-N, quercetin 3-O--D-glucofuranoside, ZX-AFC000122, BDBM153265, HMS2051B17, ZINC4096845, BDBM50241354, MFCD00017746, PDSP1_001363, PDSP2_001347, AKOS015896729, Quercetin - 3 - O - glucopyranoside, API0004007, CCG-100967, DB12665, MCULE-2852848721, NC00217, Quercetin-3-O-beta-D-galactopyranoside, Quercetin 3-O-.beta.-D-glucopyranoside, quercetin -3-O-beta-D-galactopyranoside, AS-35335, CPD000466391, LS-39589, SAM001246767, Quercetin 3-glucoside, analytical standard, FT-0686644, V0296, C05623, AB00639942-06, Quercetin 3-beta-D-glucoside, >=90% (HPLC), 3,3',4',5,7-Pentahydroxyflavone 3- -glucoside, 3-Glucopyranosyloxy-3',4',5,7-tetrahydroxyflavone, I07-0180, Q-100268, BRD-K73991644-001-01-7, 3,3'',4'',5,7-pentahydroxyflavone-3-beta-O-glucoside, Isoquercitrin, primary pharmaceutical reference standard, 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one, 2-Hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl b-D-glucopyranoside, 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-, 1012316-11-8, 107438-55-1, 1246962-26-4, 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chromen-4-one, 2-(3,4-Dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one, 9CI, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one, 27215-07-2, 28454-82-2, 3,3 inverted exclamation marka,4 inverted exclamation marka,5,7-Pentahydroxyflavone 3-|A-glucoside, 355806-24-5, 478367-76-9, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxy-phenyl)-3-(.beta.-D-glucofuranosyloxy)-5,7-dihydroxy-, 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-, 61277-38-1, 888937-01-7


ID: 1653

chemical graph of compound 1653



InChIKey: OVTKCGJIOHGDAN-HMQLAQMASA-N
SMILES: CCC(C)C(=O)OC1[C@@H]2CC3=C4CC(=O)O[C@H]([C@@]4(CCC3[C@@](C2=O)([C@H](C1(C)C)CC(=O)OC)C)C)C5=COC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708530
synonyms found at PubChem are:
KHAYASIN, KBio2_006152, Spectrum_000536, SpecPlus_000055, Spectrum2_000395, Spectrum3_000695, Spectrum4_001298, Spectrum5_000055, BSPBio_002449, KBioGR_001675, KBioSS_001016, DivK1c_006151, SPBio_000609, CHEMBL3039236, KBio1_001095, KBio2_001016, KBio2_003584, KBio3_001669, NCGC00178648-01, SR-05000002750, SR-05000002750-1


ID: 1654

chemical graph of compound 1654



InChIKey: OWBBGEXHBDJSGX-UHFFFAOYSA-N
SMILES: CC(C1=NC(=O)C2=CC=CC=C2N1)N3CCN(CC3)S(=O)(=O)C4=CC=C(C=C4)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"CE Bear" "LJ Huan" "P Kim Chiaw" "M Ramjeesingh" "L Wellhauser"


CID is 23632286
synonyms found at PubChem are:
2-{1-[4-(4-Methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3H-quinazolin-4-one, SCHEMBL3821548, OWBBGEXHBDJSGX-UHFFFAOYSA-N, KB-13575, EC-000.0199, 2-(1-{4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl}ethyl)-4-quinazolinol, 4-quinazolinol, 2-[1-[4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl]ethyl]-, 815590-48-8


ID: 1655

chemical graph of compound 1655



InChIKey: OWEXQJSSKQXXSX-UHFFFAOYSA-M
SMILES: CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)[O-].O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6420028
synonyms found at PubChem are:
Nalidixic acid sodium salt hydrate, NALIDIXATE SODIUM, UNII-J17QL41ZAG, 15769-77-4, Nalidixate sodium [USAN], J17QL41ZAG, Nalidixate sodium (USAN), NALIDIXIC ACID, SODIUM SALT HYDRATE, Prestwick_827, Prestwick-03C08, Nalidixate sodium monohydrate, CHEMBL1741367, HMS1568F15, SBB057795, AKOS024307496, AKOS025116959, NCGC00017155-01, NCGC00017155-02, 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-, sodium salt, monohydrate, WIN 18,320-3, ST50319987, D05110, 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt, Sodium 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate monohydrate


ID: 1656

chemical graph of compound 1656



InChIKey: OWRADFDDJVNMGL-UHFFFAOYSA-N
SMILES: COC1=C(C(=CC=C1)OC)OCCNCC2CSC3=CC=CC=C3O2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 10386130
synonyms found at PubChem are:
Benoxathian hydrochloride, Benoxathian HCl, 92642-97-2, 2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride, EU-0100225, MLS000860037, CHEMBL544713, Benoxathian hydrochloride, solid, DTXSID80439112, Tox21_500225, MFCD00055188, API0008377, CCG-221529, LP00225, NCGC00093693-01, NCGC00260910-01, LS-41596, SMR000326895, B-016, SR-01000075253, SR-01000075253-1, BENOXATHIAN HYDROCHLORIDE SELECTIVE A1 A DRENORE, 2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxanthian hydrochloride


ID: 1657

chemical graph of compound 1657



InChIKey: OWULVAZDMWJBLB-UHFFFAOYSA-N
SMILES: C1CCN(CC1)CC(COC(=O)NC2=CC=CC=C2)OC(=O)NC3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 10830
synonyms found at PubChem are:
DIPERODON HYDROCHLORIDE, Diperocaine, 537-12-2, Proctodon, Diperodon (hydrochloride), Diothane hydrochloride, Diperdon hydrochloride, Diperodon HCl, EINECS 208-659-8, NSC 76069, 3-Piperidino-1,2-propanediol dicarbanilate hydrochloride, 3-(1-Piperidyl)-1,2-propanediol dicarbanilate hydrochloride, DSSTox_CID_25324, DSSTox_RID_80803, DSSTox_GSID_45324, 1,2-Propanediol, 3-piperidino-, dicarbanilate, hydrochloride, 101-08-6 (Parent), C22H27N3O4.ClH, Prestwick_673, NCGC00016500-01, CAS-537-12-2, AC1L1W1H, MLS002154257, SCHEMBL1169004, CHEMBL1456312, DTXSID1045324, MolPort-003-941-170, HMS1568L22, Pharmakon1600-01505780, HY-B1226, NSC76069, Tox21_110460, 2380AH, NSC-76069, NSC759247, AKOS024374933, Tox21_110460_1, API0016327, CCG-213549, CS-4874, MCULE-4175436719, NSC-759247, NCGC00166142-04, SMR001233518, Diperodon hydrochloride, analytical standard, LS-120720, LS-120721, LS-120722, LS-120723, FT-0737296, ST51014991, SR-01000841186, SR-01000841186-2, 1, 3-piperidino-, dicarbanilate (ester), monohydrochloride, 1, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), monohydrochloride, 1,2-Propanediol, 3-piperidino-, dicarbanilate (ester), monohydrochloride, 3-(piperidin-1-yl)propane-1,2-diyl bis(phenylcarbamate) hydrochloride, [2-(phenylcarbamoyloxy)-3-piperidin-1-ylpropyl] N-phenylcarbamate hydrochloride, 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), monohydrochloride, 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), monohydrochloride (9CI), 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamato) (ester), monohydrochloride, 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamato) (ester), monohydrochloride (9CI), 1,2-Propanediol, 3-piperidino-, dicarbanilate (ester), monohydrochloride (8CI), N-phenyl[2-(N-phenylcarbamoyloxy)-1-(piperidylmethyl)ethoxy]carboxamide, chlor ide, AKOS026749866


ID: 1658

chemical graph of compound 1658



InChIKey: OXGUCUVFOIWWQJ-HQBVPOQASA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5280459
synonyms found at PubChem are:
quercitrin, 522-12-3, Quercetrin, Quercetin 3-rhamnoside, Quercitroside, Quercimelin, Thujin, Quercetin 3-L-rhamnoside, Quercitronic acid, Quercetin 3-O-rhamnoside, UNII-2Y8906LC5P, CHEBI:17558, Quercetin 3-O-alpha-L-rhamnoside, Quercetin-3-L-rhamnoside, 3,3',4',5,7-Pentahydroxyflavone-3-L-rhamnoside, Quercetin-3-rhamnoside, NSC9221, Quercetin, 3-(6-deoxy-alpha-L-mannopyranoside), 2Y8906LC5P, Mannopyranoside, quercetin-3 6-deoxy-, alpha-L-, Quercetin 3-O-alpha-rhamnopyranoside, Usaf cf-2, Quercetrin-3-O-rham, Rhamnosyl-3-quercitin, Quercitin-3-rhamnoside, luteolin 6-deoxy-alpha-L-mannopyranoside, Rhamnoside, quercetin-3, Quercetin-3-O-rhamnoside, C.I. 75720, HSDB 4339, NCI-C60102, EINECS 208-322-5, Quercetin 3-O-alpha-L-rhamnopyranoside, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, BRN 0068135, CI 75720, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one, AI3-36095, Quercetin 3-O-L-rhamnoside, CHEMBL82242, Quercetin 3-O-rhamnopyranoside, Flavone, 3,3',4',5,7-pentahydroxy-, 3-rhamnoside, Flavone, 3,3',4',5,7-pentahydroxy-, 3-(6-deoxy-alpha-L-mannopyranoside), 4gue, Quercitroside,(S), 3-((6-Deoxy-alpha-L-mannopyranosyl)-oxy)-2-(3,4-dihydr oxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 3-((6-deoxy-.alpha.-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, 4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, 4H-1-Benzopyran-4-one, 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, QCT, 5,7-dihydroxy-3-, D07DJS, AC1NQX24, BIDD:PXR0076, 2-(3,4-dihydroxyphenyl)-, 5-18-05-00514 (Beilstein Handbook Reference), MLS002472998, SCHEMBL147092, MEGxp0_000185, ACon1_000189, BDBM84978, cid_5280459, 5-trihydroxy-6-methyltetrahydro-, DTXSID50200230, MolPort-000-882-121, OXGUCUVFOIWWQJ-HQBVPOQASA-N, HMS2219D24, QUERCETIN 3-A-L-RHAMNOSIDE, 3-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-benzopyran-4-one, HY-N0418, ZINC4175638, BDBM50056315, MFCD00016932, AKOS000278033, API0004008, CS-5408, MCULE-7562123660, SMP1_000253, AC-20295, AN-45535, BC216298, CC-34149, O981, SC-26573, SMR001397103, AB0016764, KB-180086, FT-0603445, N1840, C01750, ((2S,3R,4R,5R,6S)-3,4,, 522Q123, C-22454, I07-0264, Q-100588, Q-100945, Quercitrin, primary pharmaceutical reference standard, BRD-K98601533-001-01-7, Flavone, 3,3',4',5, 7-pentahydroxy-, 3-rhamnoside, 3-O-a-L-Rhamnopyranosyloxy-3',4',5,7-tetrahydroxyflavone, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-.alpha.-L-mannopyranoside, 3-((6-Deoxy-alpha-L-mannopyranosyl)-oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 3-[(6-deoxy-a-l-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4h-benzopyran-4-one, 4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- (9CI), 4H-1-Benzopyran-4-one,3-[(6-deoxy-a-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-


ID: 1659

chemical graph of compound 1659



InChIKey: OYCAEWMSOPMASE-XFULWGLBSA-N
SMILES: CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957535
synonyms found at PubChem are:
125941-87-9, SCH 23390 HYDROCHLORIDE, R(+)-SCH-23390 hydrochloride, SCH-23390 hydrochloride, UNII-4S8T3E2F4Z, (R)-(+)-Sch 23390 Hydrochloride, 4S8T3E2F4Z, SCH 23390 (hydrochloride), R(+)SCH23390 hydrochloride, (5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride, R(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride, (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride, SMR000326935, EU-0100456, SCH23390(hydrochloride), MLS000759024, MLS000860077, MLS001424251, SCHEMBL1774187, CHEMBL1256645, DTXSID9074484, CTK8E8451, KS-00001DFJ, (R)-Sch 23390 Hydrochloride, AOB5687, MolPort-003-940-909, R(+)-7-Chloro-8-hydroxy-3-, BCP20717, R(+)-SCH-23390 HCl, Tox21_500456, HY-19545A, AKOS024458699, CCG-101196, CS-6480, LP00456, NC00446, 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, hydrochloride, (5R)-, NCGC00261141-01, AS-16912, CPD000326935, LS-28021, SAM001247098, RT-015674, B6506, FT-0674536, SR-01000075380, SR-01000597829, J-005303, SR-01000075380-1, SR-01000597829-1, R(+)-SCH-23390 hydrochloride, >=98% (HPLC), solid, methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride


ID: 1660

chemical graph of compound 1660



InChIKey: OYHLRJGDELITAF-INIZCTEOSA-N
SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)CCl)NC(=O)OCC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 99625
synonyms found at PubChem are:
ZPCK, Z-L-Phe chloromethyl ketone, 26049-94-5, Z-Phe-chloromethylketone, L-Carbobenzyloxyphenylalanyl chloromethyl ketone, NSC 251810, CHEMBL303579, OYHLRJGDELITAF-INIZCTEOSA-N, N-Carbobenzoxy-L-phenylalanyl-chloromethyl ketone, Benzyl ((1S)-3-chloro-2-oxo-1-benzylpropyl)carbamate, (S)-Benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate, 1-BENZYLOXYCARBONYLAMINOPHENETHYL CHLOROMETHYL KETONE, Carbamic acid, [(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, Carbamic acid, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, Z-Phe-CMK, N-((Benzyloxy)carbonyl)-L-phenylalanine chloromethyl ketone, Carbamic acid, ((1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl)-, phenylmethyl ester, Carbamic acid, N-((1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl)-, phenylmethyl ester, EINECS 247-432-8, PubChem11552, N(.alpha.)-Benzyloxycarbonylphenylalanylchloromethane, Spectrum2_001493, Spectrum3_001809, Lopac-C-9511, N-(Benzyloxycarbonyl)-L-phenylalanine chloromethyl ketone, Lopac0_000290, N(alpha)-Benzyloxycarbonylphenylalanylchloromethane, BSPBio_003397, L-(.alpha.-(Chloroacetyl)phenethyl)carbamic acid, benzyl ester, MLS002153274, SPBio_001505, SCHEMBL4980616, KBio3_002900, MolPort-003-939-363, HMS2235O11, HMS3260J22, L-(alpha-(Chloroacetyl)phenethyl)carbamic acid, benzyl ester, AC1L4111, Z-L-Phe chloromethyl ketone, 98%, ZINC1583409, Tox21_500290, BDBM50085339, CCG-39201, AKOS015888878, LP00290, ACM26049945, Carbamic acid, [3-chloro-2-oxo-1-(phenylmethyl)propyl]-, phenylmethyl ester, (S)-, NCGC00015284-01, NCGC00093742-01, NCGC00093742-02, NCGC00093742-03, NCGC00093742-04, NCGC00260975-01, AK326229, AS-35328, SMR001230710, benzyloxycarbonyl-phenylalanyl chloromethane, EU-0100290, FT-0603934, Z5790, C 9511, K-6751, SR-01000075792, 1-benzyloxycarbonylaminophenethyl chloromethyl ketone, SR-01000075792-1, (S)-Benzyl (1-benzyl-3-chloro-2-oxopropyl)carbamate, [N-(benzyloxycarbonyl)-L-phenylalanyl]methyl chloride, I01-16727, (3S)-3-benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanone, benzyl N-[(1S)-1-benzyl-3-chloro-2-oxo-propyl]carbamate, N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone; ZPCK, benzyl N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]carbamate, ((S)-1-Benzyl-3-chloro-2-oxo-propyl)-carbamic acid benzyl ester, Carbamic acid, (.alpha.-(chloroacetyl)phenethyl)-, benzyl ester, L-, Carbamic acid, (3-chloro-2-oxo-1-(phenylmethyl)propyl)-, phenylmethyl ester, (S)- (9CI), CARBAMIC ACID,N-[(1S)-3-CHLORO-2-OXO-1-(PHENYLMETHYL)PROPYL]-, PHENYLMETHYL ESTER


ID: 1661

chemical graph of compound 1661



InChIKey: OYIFNHCXNCRBQI-BYPYZUCNSA-N
SMILES: C(C[C@@H](C(=O)O)N)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 92136
synonyms found at PubChem are:
L-2-Aminoadipic acid, 1118-90-7, (S)-2-aminohexanedioic acid, (2S)-2-aminohexanedioic acid, L-alpha-Aminoadipic acid, L-alpha-Aminoadipate, h-aad-oh, L-Homoglutamic acid, l-2-amino adipic acid, L-2-Aminoadipate, homoglutamic acid, UNII-88ZH74L7SR, l-a-aminoadipic acid, h-l-2-aad-oh, H-DL-Aad-OH, 2-Aminoadipic acid, L-, hexanedioic acid, 2-amino-, (2S)-, L-2-Aminohexanedioate, CHEMBL88804, 88ZH74L7SR, CHEBI:37023, Aminoadipate, L--Aminoadipic acid;(S)-2-Aminohexanedioic acid;H-Homoglu-OH, DL--Aminoadipic acid;(RS)-2-Aminohexanedioic acid;H-DL-Homoglu-OH, L-|A-aminoadipic acid, Adipic acid, 2-amino-, (S)-2-Aminoadipic acid, alpha-Aminoadipate, L-, alpha-Aminoadipic acid, DL-, L-alpha-Aminoadipatic acid, EINECS 210-960-4, UN1, Hexanedioic acid, 2-amino-, (S)-, h-2-aad-oh, l-a-aminohexanoic acid, (S)-Aminoadipic Acid, L-a- Aminoadipic acid, L-2-amino-adipic acid, AC1L3NHS, AC1Q5VUR, alpha-Aminoadipate, DL-, aminoadipic acid, l-2-, L -alpha-aminoadipic acid, (2S)-2-aminoadipic acid, (+-)-2-Aminoadipic acid, l-alpha-aminohexanedioic acid, Lopac0_000091, SCHEMBL97323, KSC493I2B, (S)-2-amino-hexanedioic acid, (2S)-2-Amino-hexanedioic Acid, CTK3J3420, MolPort-002-499-455, OYIFNHCXNCRBQI-BYPYZUCNSA-N, HMS3260C04, 626-71-1, KS-00000YV4, L-2-Aminoadipic acid, 98% 1g, ZINC1532798, Tox21_500091, ANW-43725, BDBM50052553, CA-971, MFCD00002636, AKOS015920301, API0003114, CCG-204186, LP00091, RTR-034063, L-2-Aminoadipic acid, >=98% (TLC), NCGC00093593-01, NCGC00093593-02, NCGC00093593-03, NCGC00260776-01, AJ-26813, AN-48557, AS-13597, BR-25294, I861, KB-04142, SC-10038, AB0013911, AX8002960, DB-011765, TR-034063, EU-0100091, FT-0627628, A 7275, C00956, M-3010, 118A907, SR-01000075684, J-002657, SR-01000075684-1, Aad; (S)-2-Aminohexanedioic acid; L-Homoglutamic acid, 9EF7020B-8995-4D0E-BE44-34D8F18766DF, UNII-1K7B1OED4N component OYIFNHCXNCRBQI-BYPYZUCNSA-N


ID: 1662

chemical graph of compound 1662



InChIKey: OZKTVDIYALBSMA-UHFFFAOYSA-N
SMILES: CN1C2CCC1CC(C2)OC(=O)C3=CC(=C(C=C3)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 443007
synonyms found at PubChem are:
Fillalbin, Phyllalbine, Prestwick_1029, AC1L9DUK, CHEBI:8176, 4540-25-4, Prestwick0_000691, Prestwick1_000691, Prestwick2_000691, C10863, SPBio_002762, CHEMBL2165592, CTK4I8780, DTXSID20332037, (8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL) 4-HYDROXY-3-METHOXY-BENZOATE, OZKTVDIYALBSMA-UHFFFAOYSA-N, HMS1570K03, ACM4540254, CCG-208355, (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-hydroxy-3-methoxy-benzoate, (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-hydroxy-3-methoxybenzoate


ID: 1663

chemical graph of compound 1663



InChIKey: OZMRLACVWBNMCP-UHFFFAOYSA-N
SMILES: C(C1=C(C)C=CS1)1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MT Mazzei" "M Giampieri" "M Mazzei" "M Zacchigna" "N Pedemonte" "P Fossa" "F Cateni" "LJ Galietta"


CID is 698099
synonyms found at PubChem are:
Dimethyl 2,6-dimethyl-4-(3-methylthiophen-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate, AC1LF5SF, Oprea1_032064, CHEMBL593173, MolPort-000-419-203, ZINC2480752, CCG-20387, STK809050, AKOS001669582, MCULE-9550272023, SR-01000492849, SR-01000492849-1, Z57464747, 3,5-dimethyl 2,6-dimethyl-4-(3-methylthiophen-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate, DIMETHYL 2,6-DIMETHYL-4-(3-ME-2-THIENYL)-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE, dimethyl 2,6-dimethyl-4-(3-methylthien-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate, 158778-13-3, 2,6-Dimethyl-4-(3-methyl-2-thienyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester


ID: 1664

chemical graph of compound 1664



InChIKey: PAZSYTCTHYSIAO-WVFSJLEKSA-N
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)OC4C5=CC=CC=C5C(=O)O4)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 71446
synonyms found at PubChem are:
talampicillin hydrochloride, Yamacillin, Talampicillin HCl, Talpen, 39878-70-1, BRL 8988, Talampicillin hydrochloride [USAN:JAN], (2S,5R,6R)-6-((R)-2-Amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ester with 3-hydroxyphthalide, monohydrochloride, CHEBI:34993, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, monohydrochloride, (2S-(2alpha,5alpha,6beta(S*)))-, PC 183, Aseocillin (TN), BRL 8988 Hydrocloride, AC1L2G6E, AC1Q62AJ, C24H23N3O6S.HCl, BRL-8988 HCl, MLS002154099, SCHEMBL193926, BRL 8988 HYDROCHLORIDE, CHEMBL1411731, HMS1571I21, AKOS030530552, API0016125, 3-oxo-1,3-dihydro-2-benzofuran-1-yl(2s,5r,6r)-6-{[(2r)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride(1:1), SMR001233407, Talampicillin hydrochloride (JP17/USAN), LS-149728, C13978, D02201, SR-01000838844, SR-01000838844-2, (3-oxo-1H-2-benzofuran-1-yl) (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, monohydrochloride,(2S-(2-alpha,5-alpha,6-beta-(S*)))-


ID: 1665

chemical graph of compound 1665



InChIKey: PBCBXDLSTLVGDE-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC3=C2OC(=CC3=O)C4=CC=CC=C4F

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 11415057
synonyms found at PubChem are:
CHEMBL361608, 2-(2-Fluoro-phenyl)-benzo[h]chromen-4-one, D03IQX, BDBM50159614, 2-(2-fluorophenyl)-4H-benzo[h]chromen-4-one, 133367-37-0


ID: 1666

chemical graph of compound 1666



InChIKey: PBCZLFBEBARBBI-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5319
synonyms found at PubChem are:
sulfabenzamide, 127-71-9, Sulfabenzide, Sulfabenzid, Sulfabenzoylamide, N-Sulfanilylbenzamide, N-Sulfamylbenzamide, N-Benzoylsulfanilamide, Sulfamylbenzamide, Sulfabenzamid, Sulfabenzamida, Sulfabenzamidum, N-(p-Aminobenzenesulfonyl)benzamide, Benzamide, N-[(4-aminophenyl)sulfonyl]-, N-[(4-Aminophenyl)sulfonyl]benzamide, Benzamide, N-sulfanilyl-, N-(4-aminophenyl)sulfonylbenzamide, N-(4-Aminobenzenesulfonyl)benzamide, N(sup1)-Benzoylsulfanilamide, N-((4-Aminophenyl)sulfonyl)benzamide, Sulfanilamide, N(sup1)-benzoyl-, UNII-G58F8OPL4I, NSC 74587, Sulfabenzamidum [INN-Latin], Sulfabenzamida [INN-Spanish], N(sup 1)-Benzoylsulfanilamide, C13H12N2O3S, N1-Benzoylsulfanilamide, Sulfanilamide, N(sup 1)-benzoyl-, EINECS 204-859-4, BRN 2139003, G58F8OPL4I, Benzamide, N-((4-aminophenyl)sulfonyl)-, AI3-08024, MLS000069716, PBCZLFBEBARBBI-UHFFFAOYSA-N, N-(4-aminophenylsulfonyl)benzamide, NSC74587, N-[p-Aminobenzene-sulfonyl]benzamide, NCGC00016385-01, CAS-127-71-9, SMR000058257, DSSTox_CID_25287, DSSTox_RID_80783, DSSTox_GSID_45287, n-((4-aminophenyl)sulfonyl)-benzamid, Sulfabenzamide(SB), SR-01000000178, Sulfabenzamide [USAN:INN], Sulphabenzamide, Prestwick_1019, Sulfabenzamide [USAN:USP:INN:BAN], Sulphabenzamide, USP, Spectrum_000982, Opera_ID_1271, Prestwick0_000711, Prestwick1_000711, Prestwick2_000711, Prestwick3_000711, Spectrum2_001317, Spectrum3_000569, Spectrum4_000341, Spectrum5_001066, Sulfabenzamide (USP/INN), Sulfanilamide, N1-benzoyl-, CHEMBL1243, SCHEMBL93841, BSPBio_000921, BSPBio_001958, KBioGR_000741, KBioSS_001462, 4-14-00-02664 (Beilstein Handbook Reference), DivK1c_000537, SPECTRUM1500544, SPBio_001413, SPBio_002842, AC1L1K38, BPBio1_001015, DTXSID7045287, CHEBI:94677, CTK8B3740, HMS501K19, KBio1_000537, KBio2_001462, KBio2_004030, KBio2_006598, KBio3_001458, MolPort-003-666-285, N-benzoyl4-aminobenzenesulfonamide, NINDS_000537, HMS1570O03, HMS1921A09, HMS2092I11, HMS2097O03, HMS2234F05, HMS3372C11, HMS3714O03, Pharmakon1600-01500544, 4-Amino-N-benzoylbenzenesulfonamide, N-benzoyl-4-aminobenzenesulfonamide, HY-B0960, KS-00000XU5, ZINC5421253, Tox21_110410, ACM127719, ANW-43070, BBL028006, CCG-39255, HTS000823, MFCD00044890, NSC-74587, NSC757322, s4576, SBB058185, STK985629, SULFABENZAMIDE (TRIPLE SULFA), 4-Amino-N-benzoylbenzenesulfonamide #, AKOS000482643, Tox21_110410_1, API0012870, BS-4997, CS-4442, MCULE-6208267608, N-[(4-aminophenyl)sulfonyl]-benzamide, NSC-757322, IDI1_000537, NCGC00016385-02, NCGC00016385-03, NCGC00016385-04, NCGC00016385-05, NCGC00016385-06, NCGC00016385-08, NCGC00022347-03, NCGC00022347-04, AC-24189, AN-23007, LS-27410, P880, SC-77435, SBI-0051518.P003, TR-003958, AB00052093, FT-0631744, H2426, S0582, ST50307136, D05946, AB00052093_15, 4-amino-N-(1-phenyl-methanoyl)-benzenesulfonamide, C-36583, Sulfabenzamide, VETRANAL(TM), analytical standard, J-005533, SR-01000000178-2, SR-01000000178-3, BRD-K59983611-001-05-2, BRD-K59983611-001-15-1, I14-44876, Sulfabenzamide, United States Pharmacopeia (USP) Reference Standard, BS4


ID: 1667

chemical graph of compound 1667



InChIKey: PBMSWVPMRUJMPE-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 4806
synonyms found at PubChem are:
phthalylsulfathiazole, 85-73-4, Sulfathalidine, Phthalazol, Phthalylsulphathiazole, Phthalazole, Phthalylsulfonazole, Cremothalidine, Sulphaphthalyl, Enteramida, Entexidina, Phtalazol, Phthalylnorsulfazole, Sulfaphthalazole, Intestiazol, Phthalidin, Sulfacetil, Thalistanin, Thalistatyl, Ultratiazol, Ftalazol, Ftalysept, Sulftalyl, Taleudron, Talidine, Taloudron, Thalazole, Thalinil, Entero-sulfina, Ftalil-Esteve, Ftalil-Septol, Phthaloylsulfathiazole, AFI-Ftalyl, Phthalazolum, Entexidin, Ftalylsulfathiazol, 4'-(2-Thiazolylsulfamyl)phthalanilic acid, Phtalylsulfathiazol, 4'-(2-Thiazolylsulfamoyl)phthalanilic acid, 2-(p-N-Phthalylsulfanilyl)aminothiazole, Phthalylsulfathiazolum, 2-(p-Phthalylaminobenzenesulfamido)thiazole, 2-(N4-Phthalylaminobenzenesulfonamide)thiazole, N4-Phthalylsulfathiazole, Ftalilsofatiazolo [DCIT], (o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole, Phthalylsulfathiazole(PST), Ftalylsulfathiazol [Czech], NSC 66454, NSC 683525, Ftalilsulfatiazol [INN-Spanish], 2-(N(sup4)-Phthalylsulfanilamido)thiazole, Phtalylsulfathiazol [INN-French], 2-(N(sup 4)-Phthalylsulfanilamido)thiazole, UNII-6875L5852V, Phthalylsulfathiazolum [INN-Latin], EINECS 201-627-4, Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)-, 2-((4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid, Phthalylsulfathiazole [INN], 2-(N(sup 4)-Phthalyaminobenzenesulfonamide)thiazole, 2-(N(sup 4)-Phthalyaminobenzenesulfonamido)thiazole, AI3-18632, MLS002693575, CHEBI:9336, Sulfanilamide, N(sup 4)-(o-carboxybenzoyl)-N'-2-thiazolyl-, Benzoic acid, 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-, NSC66454, 2-(N4-phthalylsulfanilamido)thiazole, NSC683525, CAS-85-73-4, NCGC00016337-02, 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid, 2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid, 2-{[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl}benzoic acid, 6875L5852V, 2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid, DSSTox_CID_3470, Benzoic acid, 2-(((4-((2-thiazolylamino)sulfonyl)phenyl)amino)carbonyl)-, Phthalylsulfathiazole (INN), DSSTox_RID_77039, DSSTox_GSID_23470, Ftalilsofatiazolo, Ftalilsulfatiazol, 2-[({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)carbonyl]benzoic acid, SMR001233366, SR-05000001793, 2-(((4-((2-Thiazolylamino)sulfonyl)phenyl)amino)carbonyl)-benzoic acid, 2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-benzoic acid, Sulfaphtalylthiazol, phthalylsulfathiazol, Prestwick_980, Phthalylsulfathiazole [USP:INN:BAN], Phthalylsulfhathiazole, Phthalylsulphathiozole, Spectrum_000047, AC1L1IZW, Prestwick0_000869, Prestwick1_000869, Prestwick2_000869, Prestwick3_000869, Spectrum3_001486, Spectrum4_000154, Spectrum5_001147, component of Sulfathalidine, phthalylsulfathiazole sodium, EC 201-627-4, Oprea1_620492, BSPBio_000917, BSPBio_003071, KBioGR_000628, KBioSS_000427, MLS002154042, DivK1c_001029, SCHEMBL152662, SPECTRUM1502021, SPBio_002838, AC1Q6W29, BPBio1_001009, CHEMBL1524273, DTXSID8023470, CTK5F5682, HMS503M19, KBio1_001029, KBio2_000427, KBio2_002995, KBio2_005563, KBio3_002571, MolPort-001-783-534, NINDS_001029, PBMSWVPMRUJMPE-UHFFFAOYSA-N, HMS1570N19, HMS1921D22, HMS2092N19, HMS2097N19, HMS2230G21, HMS3374A01, HMS3714N19, Pharmakon1600-01502021, AC1Q7245, AC1Q7246, HY-B1407, KS-000013AK, phthalylsulfathiazole monosodium salt, ZINC1530877, Tox21_110380, ANW-43278, NSC-66454, NSC758159, STK730435, WLN: T5N CSJ BMSWR DMVR BVQ, AKOS000745948, Tox21_110380_1, API0003838, CCG-212977, CS-4862, MCULE-8510277419, NSC-683525, NSC-758159, IDI1_001029, NCGC00016337-01, NCGC00016337-03, NCGC00016337-05, NCGC00094943-01, NCGC00094943-02, 63868-70-2 (mono-hydrochloride salt), AC-19044, AK163563, AN-42323, BAS 00316135, SC-77394, ST072020, SBI-0051702.P002, SBI-0051702.P003, AX8147944, KB-282201, LS-109105, 2-(N4-phthalyaminobenzenesulfonamide)thiazole, AB00052257, FT-0631402, ST24038977, 2-(N4-phthalylaminobenzenesulfonamido)thiazole, C07659, D02440, AB00052257_08, N4-(o-Carboxybenzoyl)-N'-2-thiazolyl-sulfanilamide, SR-05000001793-1, SR-05000001793-3, BRD-K64659768-001-04-5, N-[4-(Thiazol-2-ylsulfamoyl)-phenyl]-phthalamic acid, Sulfanilamide, N4-(o-carboxybenzoyl)-N'-2-thiazolyl-, 2-(4-(N-thiazol-2-ylsulfamoyl)phenylcarbamoyl)benzoic acid, N4-Phthalylsulfathiazole, VETRANAL(TM), analytical standard, 2-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid, 2-((4-[(1,3-Thiazol-2-ylamino)sulfonyl]anilino)carbonyl)benzoic acid #, 2-(N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}carbamoyl)benzoic acid, 2-[[[4-[(2-Thiazolylamino)sulfonyl]- phenyl]amino]-carbonyl]benzoic acid, 2-[[[4-[(2-Thiazolylamino)sulfonyl]-phenyl]amino]-carbonyl]benzoic acid, Benzoic acid,2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-, Phthalylsulfathiazole, European Pharmacopoeia (EP) Reference Standard


ID: 1668

chemical graph of compound 1668



InChIKey: PBPBIDMIRMWUCI-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4=CC=C(C=C4)I.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 11957651
synonyms found at PubChem are:
p-MPPI monohydrochloride, 220643-77-6, p-MPPI hydrochloride, p-Mppihydrochloride, P-Mppi HCl, EU-0100874, MLS002153331, SCHEMBL7041045, CHEMBL1256777, CTK8E8998, DTXSID10474697, AKOS027381092, LP00724, ACM220643776, SMR001230744, RT-014900, FT-0729574, M-204, SR-01000075562, J-014462, SR-01000075562-1, 4-Iodo-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-benzamide, 4-iodo-N-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-benzamide hydrochloride, 4-Iodo-N-[2-4-(methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-benzamide hydrochloride, 4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)benzamide hydrochloride, 4-Iodo-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-benzamide monohydrochloride, 4-Iodo-N-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)benzamide monohydrochloride, Benzamide, 4-iodo-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, monohydrochloride


ID: 1669

chemical graph of compound 1669



InChIKey: PBQDCZRVOQLMJN-UHFFFAOYSA-M
SMILES: CC(C)C(CO)[N+]1=CC=CC=C1.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Eda" "AS Verkman" "MJ Haddadin" "MF Springsteel" "EJ Niedzinski" "MJ Kurth" "MH Nantz" "K By" "LJ Galietta"


CID is 10655705


ID: 1670

chemical graph of compound 1670



InChIKey: PBWOIPCULUXTNY-LBKBYZTLSA-N
SMILES: CC[C@H](CC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OC(=O)C)C)C)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 5354503
synonyms found at PubChem are:
Sitosterol acetate, 915-05-9, Sitosteryl acetate, beta-Sitosterol acetate, UNII-TWI48DH01E, 3beta-Acetoxystigmast-5-ene, Stigmast-5-en-3beta-yl acetate, Acetyl-.beta.-sitosterol, NSC 11922, .beta.-Sitosteryl acetate, beta-Sitosteryl acetate, TWI48DH01E, .beta.-Sitosterol 3-acetate, 3.beta.-Acetoxystigmast-5-ene, .beta.-Sitosterol acetate, CHEBI:69433, PBWOIPCULUXTNY-LBKBYZTLSA-N, Stigmast-5-en-3.beta.-yl acetate, NSC11922, Stigmast-5-en-3.beta.-ol, acetate, Stigmast-5-en-3-ol, acetate, Acetyl-beta-sitosterol, beta-Sitosterol 3-acetate, beta-Sitosterol Acetate (contains Campesterol Acetate), SITOSTEROL,BETA, ACETATE, Stigmast-5-en-3-beta-yl acetate, Stigmast-5-en-3beta-ol, acetate, Sitosterol,.beta., acetate, Stigmast-5-en-3-yl acetate #, Stigmast-5-en-3-ol, acetate (8CI), EINECS 213-019-6, Stigmast-5-en-3-ol, acetate, (3beta)- (9CI), AC1NS5QL, SITOSTEROL, ACETATE, .beta.-Sitosterol, acetate, beta-sitosterol 3-O-acetate, BETA-SITOSTEROLACETATE, SCHEMBL168092, CHEMBL2298951, ZINC4428296, NSC-11922, S0221, C-55255, UNII-FQV3U5837K component PBWOIPCULUXTNY-LBKBYZTLSA-N, [(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate


ID: 1671

chemical graph of compound 1671



InChIKey: PBZRRADJWNBPNY-XDRMOJKASA-N
SMILES: C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)O)C)C.C(=C/C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 16219298
synonyms found at PubChem are:
(-)-Eseroline fumarate, 70310-73-5, MLS002695961, CHEMBL1256915, 104015-29-4, AOB33373, SMR001562119, RT-012426, J-001092, (-)-Eseroline fumarate salt, analytical standard, for drug analysis


ID: 1672

chemical graph of compound 1672



InChIKey: PCCZMNIBWCKFBC-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC4=C(C=C3)OCO4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 6708810
synonyms found at PubChem are:
Pseudobaptigenin methyl ether, 7-Methoxy-3',4'-methylenedioxyisoflavone, 7-methoxy-baptigenin, SMR000113183, SpecPlus_000924, AC1O8FQJ, MLS000438818, DivK1c_007020, CHEMBL583578, SCHEMBL4841617, KBio1_001964, CMLDBU00003757, HMS2224L24, HMS3327A10, CMLD3_000214, LMPK12050058, AKOS000276888, PSEUDO-BAPTIGENIN, METHYL ETHER, NCGC00160840-01, 3-(1,3-benzodioxol-5-yl)-7-methoxychromen-4-one, 3-(benzo[d][1,3]dioxol-5-yl)-7-methoxy-4H-chromen-4-one, 4253-04-7


ID: 1673

chemical graph of compound 1673



InChIKey: PCHPORCSPXIHLZ-UHFFFAOYSA-N
SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Matthes" "R Robert" "J Goepp" "JW Hanrahan" "B Kus" "SD Macknight" "D Rotin" "GW Carlile" "DY Thomas" "J Liao"


CID is 8980
synonyms found at PubChem are:
DIPHENHYDRAMINE HYDROCHLORIDE, 147-24-0, Dimedrol, Diphenhydramine HCl, Carphenamine, Bendylate, Carphenex, Cathejell, Denydryl, Diphamine, Eldadryl, Fenylhist, Noctomin, Paradryl, Restamin, Ambenyl, Felben, Prodryl, Allergival, Allergan, Benzhydramine hydrochloride, Dobacen hydrochloride, Bena, Sedopretten, Benzantin, Dimedrolum, Halbmond, Histacyl, Wehydryl, Dimedrol hydrochloride, Resmin, Vena, Benzantin hydrochloride, Sekundal-D, Diphenhydramine.HCl, Difenhydramine hydrochloride, 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, Vicks Formula 44, Diphenylhydramine hydrochloride, Caladryl, Benadryl Preservative Free, NCI-C56075, UNII-TC2D6JAD40, SK-Diphenhydramine, Sleep-Eze-3, Diphenhydramine (hydrochloride), Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride, CCRIS 2383, Diphenhydramine HCl (Benadryl), Benadryl hydrochloride, 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride, EINECS 205-687-2, NSC 33299, Tylenol PM Tablets/Caplets, TC2D6JAD40, 2-(Diphenylmethoxy)-N,N-dimethylethylamine hydrochloride, MLS000028428, Tylenol Cold Night Time Liquid, Bayer Select Night Time Pain Relief, beta-Dimethylaminoethyl benzhydryl ether hydrochloride, 2-(benzhydryloxy)-N,N-dimethylethanamine hydrochloride, Benzhydrol, beta-dimethylaminoethyl ether hydrochloride, CPD000058353, SMR000058353, Dimethylamine benzhydryl ester hydrochloride, Benadryl (TN), DSSTox_CID_537, alpha-Hydroxydiphenylmethane-beta-dimethylaminoethyl ether hydrochloride, N-[2-Diphenylmethoxyethyl]-N,N-dimethylamine, DSSTox_RID_75646, DSSTox_GSID_20537, [2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride, Dipjemhist, 2-[(diphenylmethyl)oxy]-N,N-dimethylethanamine hydrochloride, Asdrin, CHEBI:4637, 8052-21-9, SR-01000003069, NCGC00015335-09, 2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride, CAS-147-24-0, Benocten, Benzehist, Daedalon, Hydryllin, Rohydra, Valdrene, Se dopretten, [2-(diphenylmethoxy)ethyl]dimethylamine, chloride, Secundal-D, Benzhydramine HCl, 2-