CandActCFTR Seed Compounds


The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.



ID: 1001

chemical graph of compound 1001



InChIKey: ITRJWOMZKQRYTA-RFZYENFJSA-N
SMILES: CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5745
synonyms found at PubChem are:
CORTISONE ACETATE, Cortisone 21-acetate, 50-04-4, Cortone acetate, Incortin, Biocort acetate, Artriona, Cortadren, Scheroson, Cortisyl, Adreson, Irisone acetate, Cortelan, Cortistab, Ricortex, Corlin, Cortogen acetate, Compound E acetate, Cortisone monoacetate, Cortisone, 21-acetate, NSC 49420, Cortisone (acetate), Cortilen, UNII-883WKN7W8X, 11-Dehydro-17-hydroxycorticosterone-21-acetate, Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, CCRIS 3661, 11-Dehydro-17-hydroxycorticosterone acetate, EINECS 200-006-5, 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate, 883WKN7W8X, CHEBI:3897, Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate, ITRJWOMZKQRYTA-RFZYENFJSA-N, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione, 21-Acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4, 21-Acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione, NCGC00021191-07, 4-Pregnene-17,alpha,21-diol-3,11,20-trione 21-acetate, DSSTox_CID_2858, DSSTox_RID_76761, DSSTox_GSID_22858, 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate, 21-Acetoxy-4-pregnen-17alpha-ol-3,11,20-trione, 17,21-Dihydroxypregn-4-ene-3,11,20-trione-21-acetate, 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate, CAS-50-04-4, [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate, [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate, 2-((1S,10S,11S,15S,2R,14R)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0 .0<2,7>.0<11,15>]heptadec-6-en-14-yl)-2-oxoethyl acetate, 2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate, SMR000059124, Cortisone acetate (Cortone), Cortisone acetate [USP:JAN], cortison acetate, Cortisone acetate [USAN:JAN], Acetate cortisone, Cortisyl artriona, component of Neosone, Neosone (Salt/Mix), Cortisone-21-acetate, Cortone acetate (TN), D0X4RS, AC1L1L1N, AC1Q62MF, SCHEMBL4501, CHEMBL1650, Lopac0_000271, MLS000069478, MLS002207136, MLS002548859, ARONIS24358, Cortisone acetate (JP17/USP), DTXSID0022858, CTK8D6790, Cortisone 21-acetate, >=99%, MolPort-002-507-122, HMS2235D24, HMS3259N19, HMS3260H04, BCP08487, NSC49420, ZINC3875334, Tox21_113482, Tox21_500271, BDBM50455157, HY-17461A, LMST02030120, MFCD00003609, NSC-49420, SBB080776, AKOS005267225, Tox21_113482_1, AC-6827, AN-9606, CCG-204366, CS-1742, DB01380, LP00271, MCULE-8390750975, NC00677, NCGC00021191-03, NCGC00021191-06, NCGC00021191-08, NCGC00021191-09, NCGC00260956-01, AK163492, AS-13692, CC-25981, LS-55003, ST075179, AB2000655, EU-0100271, FT-0665176, S2559, ST24046370, C 3130, C08173, D00973, J10115, AB00384283-08, AB00384283_09, 003C609, C-21758, W-105993, BRD-K86161929-001-13-3, Pregn-4-ene-3,20-trione, 21-(acetyloxy)-17-hydroxy-, 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate #, 21-Acetoxy-17.alpha.-hydroxy-3,11,20-triketopregnene-4, 21-Acetoxy-17.alpha.-hydroxypregn-4-ene-3,11,20-trione, 4-Pregnen-17.alpha.,21-diol-3,11,20-trione 21-acetate, 4-Pregnene-17alpha,21-diol-3,11,20-trione 21-acetate, Pregn-4-ene-3,20-trione, 17,21-dihydroxy-, 21-acetate, 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 4-Pregnene-17.alpha.,21-diol-3,11,20-trione 21-acetate, Cortisone acetate, European Pharmacopoeia (EP) Reference Standard, Cortisone acetate, United States Pharmacopeia (USP) Reference Standard, 29253-51-8


ID: 1002

chemical graph of compound 1002



InChIKey: ITTLFOBZASCCRH-UHFFFAOYSA-N
SMILES: CC1=C(OC2=CC=CC=C2C1=O)C3=CC=C(C=C3)Br

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 11847486
synonyms found at PubChem are:
CHEMBL2235764


ID: 1003

chemical graph of compound 1003



InChIKey: IUEDHIHMVPHMPR-UHFFFAOYSA-M
SMILES: C1=CC=C(C=C1)C2=CC=[N+](C=C2)C3=CC=CC=C3CO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 10494271


ID: 1004

chemical graph of compound 1004



InChIKey: IUIHYYSAVUBPQO-UHFFFAOYSA-N
SMILES: CC1=CCC2=C(C=C3C(=C2O)C(=O)C=C(O3)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3646533
synonyms found at PubChem are:
PTAEROXYLIN, 14729-11-4, Pteroxylin, KBio2_001574, AC1MUTUT, Spectrum_001094, SpecPlus_000014, Spectrum2_000283, Spectrum3_000092, Spectrum4_000933, Spectrum5_001677, BSPBio_001644, KBioGR_001486, KBioSS_001574, SPECTRUM100513, DivK1c_006110, SCHEMBL801404, SPBio_000186, CHEMBL1527943, KBio1_001054, KBio2_004142, KBio2_006710, KBio3_000744, CHEBI:108592, CCG-39841, SDCCGMLS-0066325.P001, NCGC00095423-01, NCGC00095423-02, NCGC00179124-01, SR-05000002509, SR-05000002509-1, 5-hydroxy-2,8-dimethyl-6,9-dihydro-4H-oxepino[3,2-g]chromen-4-one, 5-hydroxy-2,8-dimethyl-6,9-dihydropyrano[3,2-h][1]benzoxepin-4-one


ID: 1005

chemical graph of compound 1005



InChIKey: IUMQXQJZIHWLIN-HSZRJFAPSA-N
SMILES: COC(=O)[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6604858
synonyms found at PubChem are:
SB 218795, 174635-53-1, SB-218795, Sb218795, CHEMBL9843, methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate, Methyl (2R)-phenyl{[(2-phenyl-4-quinolinyl)carbonyl]amino}acetate, SB 218795R, Tocris-1376, NK-3 antagonists, SB, AC1O7GYW, NK-2 antagonists, GSK, D02CCA, Lopac0_000624, MLS000862187, GTPL5764, SCHEMBL4459316, CHEBI:93066, CTK8E8576, IUMQXQJZIHWLIN-HSZRJFAPSA-N, MolPort-003-959-628, HMS2231I18, HMS3261N10, HMS3267B22, NK-3 antagonists, GlaxoSmithKline, ZINC601874, Tox21_500624, BDBM50051289, AKOS024456559, API0007579, CCG-204712, LP00624, SB 218795 R, NCGC00025131-01, NCGC00025131-02, NCGC00025131-03, NCGC00025131-04, NCGC00261309-01, SMR000326950, KB-297292, RT-015641, SB-244487, SK-797230, EU-0100624, S 8817, SR-01000075910, SR-01000597578, J-011022, SR-01000075910-1, SR-01000597578-1, BRD-K61097567-001-03-6, (-)-(R)-N-(|A-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide, (-)-(R)-N-(alpha-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide, (R)-[[2-Phenyl-4-quinolinyl)carbonyl]amino]-methyl ester benzeneacetic acid, (R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester, Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphaR)-


ID: 1006

chemical graph of compound 1006



InChIKey: IUWVALYLNVXWKX-UHFFFAOYSA-N
SMILES: CCCCOC(=O)C1=CC=C(C=C1)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2482
synonyms found at PubChem are:
Butyl 4-aminobenzoate, butamben, 94-25-7, Butesin, Butylcaine, Butyl aminobenzoate, Butesine, Butoform, Planoform, Scuroform, Scuroforme, Butyl keloform, BUTYL P-AMINOBENZOATE, 4-(Butoxycarbonyl)aniline, N-Butyl p-aminobenzoate, Benzoic acid, 4-amino-, butyl ester, 4-Aminobenzoic Acid n-Butyl Ester, n-Butyl-p-aminobenzoate, 4-Aminobenzoic acid butyl ester, Benzoic acid, p-amino-, butyl ester, p-Aminobenzoic acid butyl ester, Butsein, Butyl PABA, NSC 128464, UNII-EFW857872Q, CCRIS 5891, 4-amino butylbenzoate, p-Aminobenzoic acid, butyl ester, HSDB 4245, Butylester kyseliny p-aminobenzoove, EINECS 202-317-1, 4-Aminobenzoic acid butyl, BRN 1211465, AI3-02284, Butylester kyseliny p-aminobenzoove [Czech], MLS000028721, CHEBI:3231, IUWVALYLNVXWKX-UHFFFAOYSA-N, EFW857872Q, NSC128464, CAS-94-25-7, NCGC00016353-03, SMR000059139, DSSTox_CID_2417, DSSTox_RID_76583, DSSTox_GSID_22417, butanylcaine, zyljectin, butamben(usp), Butamben [USAN], Butamben [USAN:USP], SR-01000721933, butambene, Butamben (USP), Prestwick_994, Butesin (TN), Butyl4-aminobenzoate, butyl -4-aminobenzoate, Spectrum_000025, n-butyl 4-aminobenzoate, Opera_ID_633, SpecPlus_000829, Prestwick0_000761, Prestwick1_000761, Prestwick2_000761, Prestwick3_000761, Spectrum2_000850, Spectrum3_001848, Spectrum4_000832, Spectrum5_001496, ACMC-209rr0, WLN: ZR DVO4, 4-amino-benzoicacibutylester, AC1L1DS2, AC1Q2X8Y, AC1Q2X8Z, AC1Q66VZ, SCHEMBL81735, BSPBio_000802, BSPBio_003236, KBioGR_001403, KBioSS_000385, KSC486O9H, MLS002303044, BIDD:ER0674, DivK1c_000838, DivK1c_006925, SPECTRUM1500767, SPBio_000839, SPBio_002741, BPBio1_000884, CHEMBL127516, DTXSID7022417, CTK3I6793, HMS502J20, KBio1_000838, KBio1_001869, KBio2_000385, KBio2_002953, KBio2_005521, KBio3_002736, KS-00000IIO, MolPort-001-790-585, NINDS_000838, p-Aminobenzoic acid n-butyl ester, HMS1570I04, HMS1921G20, HMS2092K06, HMS2097I04, HMS2234M07, HMS3372C17, HMS3714I04, Pharmakon1600-01500767, HY-B1430, ZINC1530937, Tox21_110392, Tox21_200378, ANW-40234, CCG-40317, MFCD00017112, NSC757433, s4583, SBB007542, STL169355, AKOS000119787, Tox21_110392_1, CS-4822, DB11148, LS-1960, MCULE-6283966699, NE10776, NSC-128464, NSC-757433, RP25248, RTR-030885, TRA0052007, IDI1_000838, NCGC00016353-01, NCGC00016353-02, NCGC00016353-04, NCGC00016353-05, NCGC00016353-06, NCGC00016353-08, NCGC00091154-01, NCGC00091154-02, NCGC00091154-03, NCGC00091154-04, NCGC00257932-01, AC-13349, AJ-26712, AN-42682, BC206116, CJ-05219, CJ-24059, DS-13802, PARA-AMINOBENZOIC ACID BUTYL ESTER, ST059627, SBI-0051887.P002, DB-029553, KB-189278, TR-030885, 4CH-023767, A0270, AB00052407, FT-0617559, ST24046262, C07875, D00730, AB00052407_12, AE-641/05573061, I01-6155, Q-200433, SR-01000721933-2, SR-01000721933-3, BRD-K27217864-001-04-1, BRD-K27217864-001-05-8, BRD-K27217864-001-15-7, Z57126994, F2190-0449, Butamben, United States Pharmacopeia (USP) Reference Standard, degrees +/-+/-(1/2) paragraph sign inverted exclamation marko yen


ID: 1007

chemical graph of compound 1007



InChIKey: IVOMOUWHDPKRLL-HMEJCUHCSA-N
SMILES: C1[C@@H]2[C@@H](C([C@@H](O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6714006
synonyms found at PubChem are:
Prestwick0_001092, Prestwick1_001092, Prestwick2_001092, AC1O8Q0A, SPBio_003052, SCHEMBL14575138, HMS1571K06, AKOS015964989, (-)-Adenosine 3',5'-cyclic monophosphate, (4aR,6R,7aR)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol


ID: 1008

chemical graph of compound 1008



InChIKey: IVVNZDGDKPTYHK-UHFFFAOYSA-N
SMILES: CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4826
synonyms found at PubChem are:
pinacidil, (R,S)-Pinacidil, 60560-33-0, (+-)-Pinacidil, Pinacidilum, 85371-64-8, Pinacidilum [INN-Latin], Pinacidil anhydrous, P 1134, (+/-)-Pinacidil, Pinacidil (anhydrous), EINECS 262-294-9, S 1230, S-1230, N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine, CHEMBL1159, MLS000069377, 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine, 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine, Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, SMR000058360, P-154, 2-Cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)guanidine monohydrate, Guanidine, 2-cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)-, monohydrate, Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, monohydrate, Pinacidil [INN], SR-01000075340, SR-05000001757, NCGC00025188-04, 1-cyano-3-(4-pyridyl)-2-(1,2,2-trimethylpropyl)guanidine, Prestwick_396, ACMC-20mijl, Spectrum_000387, SpecPlus_000759, AC1Q4SLP, Opera_ID_1844, Prestwick0_000246, Prestwick1_000246, Prestwick2_000246, Prestwick3_000246, Spectrum2_001739, Spectrum5_001372, D02KMO, AC1L1J1H, CBiol_001878, Lopac0_001037, SCHEMBL65787, BSPBio_000032, BSPBio_001461, BSPBio_002360, KBioGR_000181, KBioSS_000181, KBioSS_000867, MLS002154248, DivK1c_006855, SPECTRUM2300270, SPBio_001818, SPBio_002251, BPBio1_000036, GTPL2412, SCHEMBL9260276, DTXSID7048249, Guanidine, N-cyano-N'-4-pyridinyl-N''-[(1R)-1,2,2-trimethylpropyl]-, BCBcMAP01_000050, BDBM86245, CHEBI:91706, CTK5F4813, KBio1_001799, KBio2_000181, KBio2_000867, KBio2_002749, KBio2_003435, KBio2_005317, KBio2_006003, KBio3_000361, KBio3_000362, IVVNZDGDKPTYHK-UHFFFAOYSA-N, Bio1_000164, Bio1_000653, Bio1_001142, Bio2_000181, Bio2_000661, HMS1361J03, HMS1568B14, HMS1791J03, HMS1922L10, HMS1989J03, HMS2089C19, HMS2094G21, HMS2095B14, HMS2234F10, HMS3263O15, HMS3267P10, HMS3371H14, HMS3402J03, HMS3712B14, Pharmakon1600-02300270, 113563-71-6, 85371-64-8 (Parent), NSC_4826, Tox21_501037, 2657AH, BDBM50103517, BDBM50240750, CCG-39493, NSC759588, AKOS001637331, AKOS025394868, API0008270, CCG-205115, CCG-222341, LP01037, MCULE-2402591602, NSC-759588, IDI1_033931, NCGC00015787-02, NCGC00015787-03, NCGC00015787-04, NCGC00015787-05, NCGC00015787-06, NCGC00025188-02, NCGC00025188-03, NCGC00025188-05, NCGC00025188-06, NCGC00025188-07, NCGC00025188-08, NCGC00095199-01, NCGC00095199-02, NCGC00095199-03, NCGC00095199-04, NCGC00188958-01, NCGC00247667-01, NCGC00261722-01, AN-35700, BC202316, KB-79743, LS-73486, SBI-0051008.P004, CAS_85371-64-8, RT-004885, EU-0101037, FT-0630932, AB00052442-04, AB00052442_05, AB00052442_06, 371P648, 560P330, SR-01000075340-1, SR-01000075340-3, SR-05000001757-1, SR-05000001757-2, BRD-A43882281-001-06-4, BRD-A43882281-001-11-4, BRD-A58207013-001-01-2, 3-cyano-2-(3,3-dimethylbutan-2-yl)-1-pyridin-4-ylguanidine, N-cyano-N'-(4-pyridyl)-N''-(1,2,2-trimethylpropyl)guanidine, (+/-)-N-Cyano-N'-4-pyridinyl-N"-(1,2,2-trimethylpropyl)guanidine, 2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine, N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine, ()-N-Cyano-N''-4-pyridinyl-N''''-(1,2,2-trimethylpropyl)guanidine, (Z)-2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine, 4N-cyanoimino(1,2,2-trimethylpropylamino)methyl-4-pyridinamine(Pinacidil), 4N-cyanoimino[1,2,2-trimethyl-(1R)-propylamino]methyl-4-pyridinamine, 4N-cyanoimino[1,2,2-trimethyl-(1S)-propylamino]methyl-4-pyridinamine, N''''-cyano-N-pyridin-4-yl-N''-[(1R)-1,2,2-trimethylpropyl]guanidine, N''''-cyano-N-pyridin-4-yl-N''-[(1S)-1,2,2-trimethylpropyl]guanidine, N-Pyridin-4-yl-N''-(1,2,2-trimethyl-propyl)-cyanoguanidine (pinacidil), ( inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine, (inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine, Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, hydrate (1:1), N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine ((+)-pinacidil), N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine (Pinacidil), 113563-69-2


ID: 1009

chemical graph of compound 1009



InChIKey: IVYPNXXAYMYVSP-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3712
synonyms found at PubChem are:
Indole-3-carbinol, 700-06-1, 3-Indolemethanol, (1H-Indol-3-yl)methanol, INDOLE-3-METHANOL, 1H-indol-3-ylmethanol, 1H-Indole-3-methanol, 3-Hydroxymethylindole, 3-Indolylcarbinol, Indinol, 3-Indole methanol, Indole 3 carbinol, 3-(Hydroxymethyl)indole, (1H-Indol-3-yl)-methanol, CCRIS 3261, I3C, UNII-C11E72455F, EINECS 211-836-2, 1H-Indol-3-Yl-Methanol, C9H9NO, NSC 525801, BRN 0121323, AI3-60090, CHEBI:24814, IVYPNXXAYMYVSP-UHFFFAOYSA-N, Prevention 4 (indole-3-carbinol), IN1455, C11E72455F, NCGC00090701-06, indol-3-ylmethan-1-ol, I0496, SMR000385784, I3C cpd, 3-Indolecarbinol, 3-Indolylmethanol, indole-3-carbinole, Indole-3-carbinol;3-Indole methanol, zlchem 356, 3-Hydroxymethylindoll, PubChem7265, 3-hydroxymethyl indole, AC1L1GJH, Spectrum2_001710, Spectrum3_001973, ACMC-209oc7, AC1Q7C3V, DSSTox_CID_11458, DSSTox_RID_78876, DSSTox_GSID_31458, BSPBio_003573, MLS001333161, MLS001333162, SCHEMBL195520, SPECTRUM1505320, SPBio_001700, 3-Indolemethanol, 97% 1g, CHEMBL155625, 1H-Indole-3-methanol (9CI), DTXSID7031458, CTK5D1676, GTPL10047, KBio3_002949, ZLC0198, MolPort-000-139-921, HMS1789O22, HMS2235E10, HMS3369B02, HMS3651I18, ZINC158743, ACN-S002804, ACT03591, BCP00087, HY-N0170, INDOLE-3-CARBINOL (I3C), KS-000008ZG, Tox21_400055, 9344AF, AM1155, ANW-35813, CCG-38786, HSCI1_000097, MFCD00005632, NSC525801, s2313, SBB004095, AKOS001075120, AC-7583, AN-8864, CS-7780, DB12881, GS-0916, LS-2173, LS20980, MCULE-6344603304, NSC-525801, RP01522, RTC-020178, SDCCGMLS-0065970.P001, SDCCGMLS-0065970.P002, VI30396, Indole-3-methanol (Indole-3-carbinol), SMP2_000172, TRA-0190502, NCGC00090701-01, NCGC00090701-02, NCGC00090701-03, NCGC00090701-04, NCGC00090701-05, NCGC00090701-07, AJ-15333, BC226969, BR-53373, CAS-700-06-1, CJ-01822, KB-52660, SC-06380, SY015976, ZB007051, AB0008317, AB1009801, KB-143577, KB-183011, KB-202551, ST2402099, TL8004925, 4CH-018038, A9256, FT-0615875, ST50308202, 00I061, I-2100, M-3233, A836732, SR-01000838318, I10-0077, SR-01000838318-3, BRD-K01815685-001-02-3, BRD-K01815685-001-07-2, Z85923165


ID: 1010

chemical graph of compound 1010



InChIKey: IWALGNIFYOBRKC-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 1330
synonyms found at PubChem are:
1,3-Dipropyl-8-p-sulfophenylxanthine, 89073-57-4, DPSPX, 1,3-Dipropyl-8-(4-sulfophenyl)xanthine, 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid, CHEMBL418333, Benzenesulfonic acid,4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-, PSPX, 4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)benzenesulfonic acid, 1,3-Dspx, 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-benzenesulfonic acid, ACMC-20ccmd, Lopac-A-022, AC1L1B8N, AC1Q6X0U, Lopac0_000145, MLS002153336, SCHEMBL1321892, CTK5G2512, DTXSID70237528, IWALGNIFYOBRKC-UHFFFAOYSA-N, HMS2231H19, HMS3260M12, HMS3374O06, ZINC9229228, Tox21_500145, BDBM50018162, AKOS027320584, CCG-204240, LP00145, VZ20604, 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)benzenesulfonic acid, 1,3-Dipropyl-8-(p-sulfophenyl)xanthine, NCGC00015001-01, NCGC00015001-02, NCGC00015001-03, NCGC00015001-04, NCGC00093635-01, NCGC00093635-02, NCGC00260830-01, SMR000326868, LS-191127, A-022, EU-0100145, FT-0606724, 1,3-Dipropyl-8-(p-sulfophenyl)xanthine, powder, C-21569, SR-01000075228, SR-01000075228-1, 4-(1,3-dipropyl-2,3,6,7-tetrahydro-2,6-dioxo-1H-purin-8-yl)benzenesulfonic acid, 4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid, Benzenesulfonic acid, 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-, 4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid:1/4 moles H2O


ID: 1011

chemical graph of compound 1011



InChIKey: IWAWCPZVTXCFKD-UHFFFAOYSA-N
SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 168993
synonyms found at PubChem are:
Pizotifen malate, Pizotyline malate, 5189-11-7, Pizotifen (malate), Sanomtgran, Mosegor, Litec malate, Pizotifen hydrogen malate, Sandomigran malate, Sandomygran malate, BC 105 malate, C19H21NS.C4H6O5, CHEBI:50213, EINECS 225-970-4, Pizotifen maleate, Sandomigran (TN), Q-201591, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxysuccinate, Malic acid, compound with 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine (1:1), Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, malate (1:1), SR-05000001896, litec; malic acid, Mosegor (TN), Sandomigran;pizotyline, AC1Q5VDI, Prestwick0_000992, Prestwick1_000992, Prestwick2_000992, Prestwick3_000992, AC1L52XC, BSPBio_001083, SCHEMBL365598, SPECTRUM1505003, SPBio_002974, BPBio1_001193, CHEMBL1592663, CTK1H0133, HY-B0115A, MolPort-002-507-853, HMS1571G05, HMS2093G20, HMS2098G05, HMS3651C11, HMS3715G05, Pharmakon1600-01505003, 2661AH, NSC758899, s1394, AKOS015907762, CCG-213329, CS-1871, NSC-758899, Sandomigran, pizotyline, 5189-11-7, NCGC00096062-01, NCGC00096062-02, AS-10171, AB2000084, LS-115014, D08397, 189P117, I14-2724, SR-05000001896-1, SR-05000001896-3, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxybutanedioate, 9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene malate (1:1), Butanedioicacid, 2-hydroxy-, compd. with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine(1:1), Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-,malate (1:1)


ID: 1012

chemical graph of compound 1012



InChIKey: IWDBEHWZGDSFHR-BTJKTKAUSA-N
SMILES: CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5358812
synonyms found at PubChem are:
Methiothepin maleate, METITEPINE MALEATE, 19728-88-2, CHEBI:64202, NSC281816, 8-Methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate, 1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine maleate, MLS000756636, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine (2Z)-but-2-enedioate, 20229-30-5, SR-01000075560, Prestwick_739, LVP2XBC3GA, UNII-LVP2XBC3GA, AC1NSD6U, SPECTRUM1503637, SCHEMBL2048660, CHEMBL1358918, DTXSID8042630, HMS502N15, AOB6250, MolPort-003-666-493, HMS1569K11, HMS2096K11, HMS3713K11, Pharmakon1600-01503637, BG0375, CCG-39505, NSC759875, AKOS024458571, NSC-281816, NSC-759875, ACM19728882, NCGC00095921-01, AS-16941, SR-01000075560-7, SR-01000075560-8, 1-[10,11-Dihydro-8-(methylthio)dibenzo(Z)[b,f]thiepin-10-yl]-4-methylpiperazine maleate, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine maleate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine maleate, (.+-.)-Metitepine maleate,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (.+-.)-, (Z)-2-butenedioate (1:1), (Z)-but-2-enedioic acid; 1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium (2Z)-but-2-enedioate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine (2Z)-but-2-enedioate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium (2Z)-but-2-enedioate, Piperazine,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (+)-, (Z)-2-butenedioate (1:1)


ID: 1013

chemical graph of compound 1013



InChIKey: IWSWDOUXSCRCKW-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 44383
synonyms found at PubChem are:
Terazosin hydrochloride, 63074-08-8, Terazosin HCl, Hytrin, Vasocard, Abbott-45975, Zayasel, Terazosin hydrochloride anhydrous, (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochloride, MLS000040261, SMR000044015, DSSTox_CID_25493, DSSTox_RID_80913, DSSTox_GSID_45493, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride, 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride, CAS-63074-08-8, 63590-64-7 (Parent), SR-01000000197, Prestwick_146, terazosine hydrochloride, Tetrazosin hydrochloride, Opera_ID_398, AC1L2BPY, NCGC00016903-01, SCHEMBL41545, MLS001077301, MLS001305722, C19H25N5O4.HCl, CHEMBL1256665, DTXSID7045493, KS-00000JKM, IWSWDOUXSCRCKW-UHFFFAOYSA-N, MolPort-003-666-790, HMS1570G04, Pharmakon1600-01505576, BCP12795, Terazosin monohydrochloride anhydrous, Tox21_110674, NSC759168, s4679, AKOS007930686, Tox21_110674_1, AC-2074, CCG-220751, LP01138, NE45355, NSC-759168, TRA0127916, VA11840, TERAZOSIN HYDROCHLORIDE (anhydrous), NCGC00016026-10, NCGC00094404-01, NCGC00094404-02, AN-14324, DS-11401, AB1009460, AB2000463, DB-018541, LS-110235, TL8004930, TR-037527, EU-0101138, FT-0605647, V1531, T 4680, Terazosin hydrochloride, >=98% (TLC), powder, 074T088, I06-0651, SR-01000000197-2, SR-01000000197-4, SR-01000000197-12, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride, 2[4-(Tetrahydro-2-furoy1)piperazinyl]-4-amino-6,7-dimethoxyquinazoline hydrochloride, 4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride, [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone hydrochloride, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine Hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-,monohydrochloride, AC1LD8ZY, AKOS026749822, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone; hydron; chloride, MolPort-000-768-720, MCULE-4508839187


ID: 1014

chemical graph of compound 1014



InChIKey: IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES: C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 37542
synonyms found at PubChem are:
ribavirin, 36791-04-5, Tribavirin, Virazole, Rebetol, Ribavirine, Copegus, Vilona, Ribamide, Ribamidil, Ribasphere, Viramid, Ribamidyl, Ribavirina, Ribavirinum, Rebetron, Varazid, RTCA, Ribavirin Capsules, Ribavirine [INN-French], Ribavirinum [INN-Latin], Ribavirina [INN-Spanish], ICN-1229, Rebretron, Ribovirin, Viramide, Virazid, Virazide, Ribav, 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, Cotronak, Ravanex, Ribacine, Ribavirin [USAN:INN], C-Virin, DRG-0028, Ribasphere (TN), Virazole (TN), 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, Copegus (TN), Rebetol (TN), UNII-49717AWG6K, Ribavirin (Copegus), 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide, HSDB 6513, SCH 18908, RBV, BRN 0892462, Ribavarin, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide, CHEBI:63580, 49717AWG6K, RG-964, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide, Ro-20-9963, Virazole (Ribavirin) Inhalation Solution, 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, R-964, DSSTox_CID_3557, EN300-59237, Ro 20-9963/000, NSC 163039, R 9644, DSSTox_RID_77081, DSSTox_GSID_23557, RTC, 1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, 1-(beta-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide, 1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide, 1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide, 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, SMR000058315, SR-01000076112, Ribavirine;, NSC163039, Drug: Ribavirin, KS-1104, Ribavirin [USAN:USP:INN:BAN], Drug: Ribavirin, Ribavirin,(S), NCGC00015904-02, Ribavirin, antiviral, CAS-36791-04-5, Vilona (TN), PubChem14187, Spectrum_001826, 4pb1, ribofluranosyl carboxamide, AC1L1XXZ, AC1Q1IDC, AC1Q4ZGS, Prestwick3_000993, Spectrum3_001876, Spectrum4_001252, Spectrum5_002075, 1-|A-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, D0DI8X, D0H3WI, SCHEMBL3727, CHEMBL1643, Ribavirin (JAN/USP/INN), Lopac0_001063, BSPBio_001085, BSPBio_003352, KBioGR_001804, KBioSS_002331, cid_37542, MLS000028486, MLS002222317, DivK1c_000782, SPECTRUM1503938, Ribavirin (JP17/USP/INN), BPBio1_001195, GTPL6842, DTXSID8023557, CTK7J7594, HMS502H04, KBio1_000782, KBio2_002328, KBio2_004896, KBio2_007464, KBio3_002854, BIB6306, IWUCXVSUMQZMFG-AFCXAGJDSA-N, MolPort-002-507-104, NINDS_000782, HMS2090L15, HMS2094O09, HMS2098G07, HMS2232P07, HMS3263E08, HMS3715G07, Pharmakon1600-01503938, BB_NC-00567, HY-B0434, ZINC1035331, Tox21_110259, Tox21_200967, Tox21_501063, BDBM50154375, CCG-38985, MFCD00058564, NSC758650, s2504, AKOS001715163, Tox21_110259_1, API0004062, CS-2540, DB00811, GS-3572, LP01063, LS-1241, MCULE-9495128592, NSC-758650, IDI1_000782, SMP1_000261, NCGC00090726-01, NCGC00090726-03, NCGC00090726-04, NCGC00090726-05, NCGC00090726-06, NCGC00090726-07, NCGC00090726-08, NCGC00090726-09, NCGC00090726-12, NCGC00258520-01, NCGC00261748-01, AJ-24715, AK-49185, AS-34178, BR-49185, CC-34249, CPD000058315, SAM002548967, SC-12159, ZB015662, BCP0726000138, SBI-0051033.P003, AB0068936, AX8005387, ST2413783, AB00430481, EU-0101063, FT-0082885, FT-0630597, FT-0649908, R0077, D00423, J10190, M-7546, AB00430481-15, AB00430481-16, AB00430481_17, AB00430481_18, RBI034 (2-5A antisense compound) + Ribavirin, 1-beta-Ribofuranosyl-1,2,4-triazole-3-carboamide, 791R045, AA-504/07617051, C-14783, SR-01000721904, SR-01000076112-2, SR-01000076112-3, SR-01000076112-4, SR-01000721904-2, BRD-K60369935-001-02-7, BRD-K60369935-001-18-3, SR-01000076112-11, 1-?-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, Ribavirin, British Pharmacopoeia (BP) Reference Standard, Z1522567185, 1-(beta -D-ribofuranosyl)-1,2,4-triazole-3-carboxamide, Ribavirin, European Pharmacopoeia (EP) Reference Standard, Ribavirin, United States Pharmacopeia (USP) Reference Standard, Ribavirin, Pharmaceutical Secondary Standard; Certified Reference Material, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,2,4-triazole-3-carboxamide, 437710-49-1, 66510-90-5


ID: 1015

chemical graph of compound 1015



InChIKey: IWVTXAGTHUECPN-ANBBSHPLSA-N
SMILES: CCOC(=O)OC(C)OC(=O)[C@H]1C(S[C@H]2N1C(=O)[C@H]2NC(=O)[C@@H](C3=CC=CC=C3)N)(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 441398
synonyms found at PubChem are:
Bacampicillin hydrochloride, bacampicillin HCl, 37661-08-8, Bacampicillin (hydrochloride), Spectrobid, Bacampicillin hydrochoride, BAPC, Ambacamp, Ambaxin, Bacacil, Velbacil, CHEBI:2969, Penglobe, DSSTox_CID_25466, DSSTox_RID_80897, DSSTox_GSID_45466, EINECS 253-580-4, Spectrobid (TN), C21H27N3O7S.HCl, (2S,5R,6R)-6-((R)-(2-Amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ester with ethyl 1-hydroxyethyl carbonate, monohydrochloride, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1-((ethoxycarbonyl)oxy)ethyl ester, monohydrochloride, (2S-(2alpha,5alpha,6beta(S*)))-, Prestwick_776, Bacampicillin hydrochloride [USAN:USP:JAN], NCGC00016837-01, SureCN721373, AC1L9B3G, CAS-37661-08-8, MLS002153801, SCHEMBL124593, CHEMBL1200965, DTXSID0045466, HY-B1149A, IWVTXAGTHUECPN-ANBBSHPLSA-N, MolPort-019-996-595, HMS1569C14, 1-((Ethoxycarbonyl)oxy)ethyl (2S-(2alpha,5alpha,6beta(S*)))-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrochloride, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1-((ethoxycarbonyl)oxy)ethyl ester, hydrochloride, 50972-17-3 (Parent), Tox21_110640, AKOS016014246, Tox21_110640_1, API0000413, CCG-220416, CS-4754, Bacampicillin hydrochloride (JP17/USP), NCGC00179582-03, SMR001233177, AX8020538, C08123, D00927, A823813, (2S,5R,6R)-6-[[(2R)-2-amino-1-oxo-2-phenylethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 1-ethoxycarbonyloxyethyl ester hydrochloride, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-7-oxidanylidene-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride, 1-[(ethoxycarbonyl)oxy]ethyl 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate hydrochloride


ID: 1016

chemical graph of compound 1016



InChIKey: IXORZMNAPKEEDV-OBDJNFEBSA-N
SMILES: C[C@@]12[C@H](C=C[C@@]3([C@@H]1[C@@H]([C@]45[C@H]3CC[C@](C4)(C(=C)C5)O)C(=O)O)OC2=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6466
synonyms found at PubChem are:
GIBBERELLIC ACID, 77-06-5, Gibberellin A3, Gibberellin, Gibreskol, Brellin, Cekugib, Grocel, Gibberellin X, Gibberellic acid GA3, Gib-Tabs, Pro-Gibb, Pro-Gibb Plus, Gib-Sol, Gibberellins A4A7, Gibefol, Regulex, Activol GA, Pgr-iv, Acide gibberellique, Gibberellins, Berelex, Gibberellinsaeure, UNII-BU0A7MWB6L, GA3, Gibrescol, Ryzup, (+)-Gibberellic Acid, Acide gibberellique [ISO-French], NCI-C55823, BU0A7MWB6L, Gibbrel, Gibberellic acid [BSI:ISO], AI3-52922, CHEBI:28833, IXORZMNAPKEEDV-OBDJNFEBSA-N, Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1alpha,2beta,4aalpha,4bbeta,10beta)-, Caswell No. 467, NCGC00091033-01, DSSTox_CID_656, 2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone, DSSTox_RID_75715, Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, DSSTox_GSID_20656, (1alpha,2beta,4aalpha,4bbeta,10beta)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone, (3S,3aR,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propenoazuleno(1,2-b)furan-4-carboxylic acid, (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid, (3S,3aS,4S,4aS,6S,8aS,8bS,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid, (3S,3aS,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propeno(1,2-b)furan-4-carboxylic acid, 2beta,4aalpha,7-Trihydroxy-1beta-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, 2beta,4alpha,7-Trihydroxy-1-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, 2beta,4alpha,7-Trihydroxy-1-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, Gibberelic acid, CCRIS 4820, HSDB 712, EINECS 201-001-0, GIBERELLIN, NSC 14190, EPA Pesticide Chemical Code 043801, GIBERILLIC ACID, BRN 0054346, (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid, 2,4alpha,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10 beta-dicarboxylic acid 1,4alpha-lactone, GIBBERELLIC ACID, 90%, GA [Plant Growth Regulator], Gibberellic acid [ISO:BSI], NSC14190, NSC19450, Gibberellin Acid, 4psb, 2,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-carboxylic acid 1-4-lactone, CAS-77-06-5, Gibberellin (GA), Gibb-3-ene-1, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1.alpha.,2.beta.,4a.alpha.,4b.beta.,10.beta.)-, Spectrum_000628, 4q0k, SpecPlus_000148, PS49_SUPELCO, Prestwick0_000965, Prestwick1_000965, Prestwick2_000965, Prestwick3_000965, Spectrum2_000311, Spectrum3_001301, Spectrum4_001444, Spectrum5_000027, gibberellic acid (ga-3), bmse000317, SCHEMBL15577, BSPBio_000969, BSPBio_002961, KBioGR_001927, KBioSS_001108, 5-18-09-00269 (Beilstein Handbook Reference), MLS001055447, MLS002154076, DivK1c_006244, G7645_SIGMA, SPBio_000302, SPBio_002890, BPBio1_001067, MEGxm0_000440, CHEMBL1232952, DTXSID0020656, ACon0_000224, ACon1_000551, BCBcMAP01_000012, KBio1_001188, KBio2_001108, KBio2_003676, KBio2_006244, KBio3_002181, U - 1,2-Dibromoethane solution, MolPort-003-931-014, HMS1571A11, HMS2098A11, HMS2231J16, HMS3039M06, (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid, ZINC3860467, 125-67-7 (mono-potassium salt), Tox21_202052, Tox21_303023, MFCD00079329, NSC-14190, NSC-19450, AKOS024464812, AKOS025310145, CCG-208472, EBD2198547, SMP1_000136, NCGC00091033-02, NCGC00091033-03, NCGC00091033-04, NCGC00091033-05, NCGC00091033-06, NCGC00091033-09, NCGC00256446-01, NCGC00259601-01, AN-23906, AS-14216, K339, NCI60_000922, SC-11963, SMR000686070, SMR001233386, AB00513979, ST24047329, Gibberellin, 80% gibberellin A3 basis (TLC), 079G329, Gibberellic acid, 90% gibberellin A3 basis (HPLC), Gibberellic acid, PESTANAL(R), analytical standard, BRD-K92758126-001-05-5, BRD-K92758126-001-06-3, BRD-K92758126-001-17-0, 6F94D8A8-3230-4AB5-93C1-46F5E84FE343, Gibberellic acid, United States Pharmacopeia (USP) Reference Standard, Gibberellic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-Dihydroxy-11-methyl-6-methylene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-13-ene-9-carboxylic acid, (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1(5,8).0(1,10).0(2,8)]heptadec-13-ene-9-carboxylic acid, 1405-96-5, 16202-20-3, 192662-67-2, 295313-57-4, 2beta,7alpha-dihydroxy-1beta-methyl-8-methylidene-13-oxo-4a,1alpha-epoxymethano-4aalpha,4bbeta-gibb-3-ene-10beta-carboxylic acid, 474760-45-7, 58915-44-9, 7121-55-3, 859282-71-6, Gibberellic acid, plant cell culture tested, BioReagent, >=90% gibberellin A3 basis (of total gibberellins.)


ID: 1017

chemical graph of compound 1017



InChIKey: IXWZKSIVLFEQNZ-UHFFFAOYSA-N
SMILES: C(C1=CC=C([NH0+](=O)[OH0-])S1)1C(C(=O)OCC2=CC=CC=C2)=C(C)NC(C)=C1C(=O)OCC1=CC=CC=C1

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Giampieri" "P Fossa" "LJ Galietta" "M Mazzei" "M Zacchigna" "F Cateni" "N Pedemonte" "MT Mazzei"


CID is 46227522
synonyms found at PubChem are:
CHEMBL604890


ID: 1018

chemical graph of compound 1018



InChIKey: IYBDWVUOOFQLSF-LLPMONEMSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C3[C@@]1(C45C(O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)(C(=O)C=CC2(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708584
synonyms found at PubChem are:
KBio2_006302, ISOGEDUNIN, Spectrum_000686, SpecPlus_000169, Spectrum2_001895, Spectrum3_001337, Spectrum4_001332, Spectrum5_000203, BSPBio_003093, KBioGR_001823, KBioSS_001166, SPECTRUM100195, DivK1c_006265, SPBio_001830, SCHEMBL13424846, KBio1_001209, KBio2_001166, KBio2_003734, KBio3_002313, CCG-38468, SDCCGMLS-0066306.P001, NCGC00178301-01, BRD-A52326238-001-02-3


ID: 1019

chemical graph of compound 1019



InChIKey: IYBQHJMYDGVZRY-UHFFFAOYSA-N
SMILES: CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6314
synonyms found at PubChem are:
Lidocaine hydrochloride, 73-78-9, LIDOCAINE HCL, Lidothesin, Xyloneural, Lignocaine hydrochloride, Laryng-O-jet, Lidocaine (hydrochloride), Xilina hydrochloride, Lidocaton, Xylocard, Rucaina hydrochloride, Xycaine hydrochloride, Xylotox hydrochloride, Duncaine hydrochloride, Isicaine hydrochloride, Lidocain hydrochloride, Anestacon hydrochloride, Gravocain hydrochloride, Leostesin hydrochloride, Xylocaine hydrochloride, Xylocitin hydrochloride, Lidothesin hydrochloride, Xylestesin hydrochloride, LIDOCAINE VISCOUS, LTA II KIT, UNII-EC2CNF7XFP, PEDIATRIC LTA KIT, LARYNG-O-JET KIT, XYLOCAINE PRESERVATIVE FREE, EC2CNF7XFP, EINECS 200-803-8, LARYNGOTRACHEAL ANESTHESIA KIT, 2-Diethylamino-2',6'-acetoxylidide hydrochloride, XYLOCAINE 4% PRESERVATIVE FREE, Lidocaine hydrochloride anhydrous, Linocaine hydrochloride, Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride, XYLOCAINE 5% W/ GLUCOSE 7.5%, MLS000069665, S 202, V 262, XYLOCAINE 1.5% W/ DEXTROSE 7.5%, alpha-Diethylamino-2,6-acetoxylidine hydrochloride, N-(Diethylaminoacetyl)-2,6-dimethylaniline hydrochloride, omega-Diethylamino-2,6-dimethylacetanilide hydrochloride, SMR000058468, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride, ALPHACAINE HCL, Glydo, 2',6'-ACETOXYLIDIDE, 2-(DIETHYLAMINO)-, HYDROCHLORIDE, LIDOCAINE HCL VISCOUS, Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride (1:1), 137-58-6 (Parent), CHEBI:50512, LIDOCAINE HCL PRESERVATIVE FREE, SR-01000000189, LIDOCAINE HCL IN PLASTIC CONTAINER, LIDOCAINE HCL 0.2% IN DEXTROSE 5%, LIDOCAINE HCL 0.4% IN DEXTROSE 5%, LIDOCAINE HCL 5% AND DEXTROSE 7.5%, ALPHACAINE HYDROCHLORIDE, Lidocaine hydrochloride viscous, Diethylamino-2,6-dimethylacetanilide Hydrochloride, lidocaine hydrochloride(jan/usp), Dalcaine (TN), LIDOCAINE HCL PRESERVATIVE FREE IN PLASTIC CONTAINER, Prestwick_296, LIDOCAINE HCL 0.2% IN DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.4% IN DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.8% IN DEXTROSE 5% IN PLASTIC CONTAINER, lidocainehydrochloride, LIDOCAINE HCL 0.1% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.2% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.8% AND DEXTROSE 5% IN PLASTIC CONTAINER, Lidoca ne hydrochloride, Lidocaine hydrochloride preservative free, Lidocaine(hydrochloride), Opera_ID_351, Lidocaine hydrochloride in plastic container, Lidocaine hydrochloride 0.2% in dextrose 5%, Lidocaine hydrochloride 0.4% in dextrose 5%, Lidocaine hydrochloride 5% and dextrose 7.5%, AC1Q5LY0, C14H22N2O.HCl, Lidocaine injection (JP17), SPECTRUM1500689, AC1L1M96, CHEMBL541521, DTXSID4058782, CTK8G0579, HY-B0185A, IYBQHJMYDGVZRY-UHFFFAOYSA-N, MolPort-003-666-319, HMS1568I21, HMS1921C22, Lidocaine hydrochloride preservative free in plastic container, Pharmakon1600-01500689, Lidocaine Hydrochloride (anhydrous), Lidocaine hydrochloride (JAN/USP), KS-00001F6P, Lidocaine hydrochloride 0.2% in dextrose 5% in plastic container, Lidocaine hydrochloride 0.4% in dextrose 5% in plastic container, Lidocaine hydrochloride 0.8% in dextrose 5% in plastic container, Tox21_500669, CCG-39281, Lidocaine hydrochloride 0.1% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.2% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.4% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.8% and dextrose 5% in plastic container, NSC757420, s4667, (unlabeled)Lidocaine-d6 Hydrochloride, AKOS015889456, API0003175, CS-3888, LP00669, NSC-757420, NCGC00094030-01, NCGC00094030-02, NCGC00094030-03, NCGC00094030-04, NCGC00094030-05, NCGC00261354-01, AC-11712, AK326167, AS-35171, BC203198, LS-13898, EU-0100669, FT-0603276, D02086, L 5647, A837924, I01-2012, I01-4416, Q-201304, SR-01000000189-3, SR-01000000189-9, 2',6'-Acetoxylidide, 2-(diethylamino)-, monohydrochloride, 2',6'-Acetoxylidide, 2-(diethylamino)-, monohydrochloride (8CI), 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide hydrochloride, AC1LCW7O, SCHEMBL29129, EBD952442, AKOS026750038, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide; hydron; chloride, Alphacaine N, Alphacaine SP, N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide hydrochloride


ID: 1020

chemical graph of compound 1020



InChIKey: IYETZZCWLLUHIJ-UTONKHPSSA-N
SMILES: C[C@H](CC1=CC=CC=C1)N(C)CC#C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 26758
synonyms found at PubChem are:
Selegiline hydrochloride, 14611-52-0, Eldepryl, Zelapar, Selegiline Hcl, (-)-Deprenyl hydrochloride, l-Deprenyl hydrochloride, Jumex hydrochloride, Eldepryl hydrochloride, Zydis selegiline, (-)-Deprenil hydrochloride, (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride, (-)-E-250 hydrochloride, UNII-6W731X367Q, L-Deprenyl, HSDB 7183, FPF1100, R-(-)-Deprenyl (hydrochloride), (-)-Phenylisopropylmethylpropynylamine, Otrasel, 6W731X367Q, (-)-(R)-N,alpha-Dimethyl-N-2-propynylphenethylamine hydrochloride, (-)-N,alpha-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride, (-)-(R)-N,alpha-Dimethyl-N-2-propynylphenethylamine monohydrochloride, DSSTox_CID_24584, DSSTox_RID_80331, DSSTox_GSID_44584, (R)-(-)-N,alpha-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride, Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, hydrochloride, (R)-, CHEBI:9087, CPD000449328, SMR000449328, C13H17N.HCl, SR-01000597928, R-(-)-Deprenyl hydrochloride, Plurimen, Seledat, Vivapryl, Xilopar, Ensam, 14611-51-9 (Parent), (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride, CCRIS 8571, Selegiline hydrochloride [USAN], L-deprenyl HCl, L-Deprenalin HCl, Eldepryl (TN), Prestwick_846, Selegiline hydrochloride [USAN:USP], E-250, NCGC00016708-01, D0J2MJ, D0OH5I, D0Y8AN, AC1L1BU2, CAS-14611-52-0, R-(-)deprenyl hydrochloride, SCHEMBL41392, MLS000758294, MLS001423947, MLS002153281, MLS002222269, CHEMBL1200904, DTXSID9044584, (R)-(-)-Deprenyl hydrochloride, IYETZZCWLLUHIJ-UTONKHPSSA-N, HMS1569P05, FPF-1100, Selegiline hydrochloride (JAN/USP), Tox21_110572, Tox21_301846, BG0405, AKOS005166822, Tox21_110572_1, API0004151, CCG-100773, CS-2764, KS-5098, NC00023, NC00605, NCGC00024994-06, NCGC00255797-01, AC-18759, CC-34395, HY-14199, LS-30157, SAM001246969, SAM002589926, AX8151001, FT-0601539, ST24035592, KS-00000059, D00785, K-4669, 611S520, SR-01000597928-1, SR-01000597928-5, SR-01000597928-6, R-(-)-Deprenyl hydrochloride, powder, >=98% (HPLC), UNII-63G7R4955A component IYETZZCWLLUHIJ-UTONKHPSSA-N, Selegiline Hydrochloride 1.0 mg/ml in Methanol (as free base), (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine hydrochloride, (R)-(-)-N-?-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride, (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-aminehydrochloride, Selegiline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Selegiline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 40602-63-9, N-methyl-N-[(1R)-1-methyl-2-phenylethyl]prop-2-yn-1-aminium chloride, (-)-( R)- N,a-Dimethyl- N-2-propynylphenethylamine hydrochloride


ID: 1021

chemical graph of compound 1021



InChIKey: IYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILES: CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 10237
synonyms found at PubChem are:
(+)-Bicuculline, bicuculline, d-Bicuculline, 485-49-4, Bicculine, Bicucullin, Bicuculline (+), UNII-Y37615DVKC, NSC 32192, C20H17NO6, EINECS 207-619-7, BRN 0098786, CHEBI:3092, CHEMBL417990, Y37615DVKC, (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one, NSC32192, Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-, (6R)-6-((5S)-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxolano[4,5-g]isoquinolin-5- yl))-6-hydro-2H-1,3-dioxoleno[4,5-e]isobenzofuran-8-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one, (R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one, SR-01000075252, Bicuculline,(+), Prestwick_96, Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-((5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (6R)-, Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (6R)-, AC1L1URW, Prestwick0_000589, Prestwick1_000589, Prestwick2_000589, Prestwick3_000589, Biomol-NT_000252, D00LBX, (+)-Bicuculline, 98%, SCHEMBL8222, Lopac0_000234, BSPBio_000438, 4-27-00-06900 (Beilstein Handbook Reference), MLS002153892, DivK1c_000609, SPBio_002657, BPBio1_000482, BPBio1_000794, GTPL2312, DTXSID3042687, HMS501O11, KBio1_000609, AOB5192, MolPort-001-728-112, NINDS_000609, HMS1569F20, HMS2096F20, HMS2235H18, HMS3266A07, HMS3652N20, BCP04180, HY-N0219, BDBM50000693, MFCD00005006, NSC-32192, PDSP2_000138, s7071, ZINC19899011, AKOS024282673, API0002224, CCG-204329, CS-5493, DB11562, IDI1_000609, NCGC00017385-06, (+)-Bicuculline, >=97.0% (TLC), 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one, AN-45228, AS-17471, LS-70680, SC-17991, SMR001233241, ST057559, ST057706, AB0019776, FT-0080946, N1592, V0271, B 9130, C09364, 485B494, C-21058, SR-01000075252-1, SR-01000075252-4, SR-01000075252-5, WLN: T C566 DO FO KN EH&&TJ K1 J- ET B565 CVO JO LO EH KHJ, (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-e][1,3]benzodioxol-8-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one, (bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium, (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one, [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-((5S)-6-methyl-5,6,7,8-tetrahydro-2H-1,3-dioxoleno[4,5-g]isoquinolin-5-yl)-6 -hydro-2H-1,3-dioxoleno[4,5-e]isobenzofuran-8-one, 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one, 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline), 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline), Furo[3,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [R-(R*,S*)]-, Furo[3,4-e]-1,3-benzodioxol-8(6H)-one,6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (6R)-


ID: 1022

chemical graph of compound 1022



InChIKey: IYNMDWMQHSMDDE-MHXJNQAMSA-N
SMILES: CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O.CC(C)(C)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 441313
synonyms found at PubChem are:
PERINDOPRIL ERBUMINE, 107133-36-8, ACEON, Perindopril tert-butylamine, Perindopril (erbumine), McN-A-2833-109, Perindopril erbumine [USAN], UNII-1964X464OJ, S-9490-3, CHEBI:8025, (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, 1964X464OJ, (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1), Aceon (TN), Covapril, 1H-Indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-, compd. with 2-methyl-2-propanamine (1:1), 2-methylpropan-2-amine (2S,3aS,7aS)-1-(((S)-1-ethoxy-1-oxopentan-2-yl)-L-alanyl)octahydro-1H-indole-2-carboxylate, (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine, C19H32N2O5.C4H11N, AC1L9AYA, Perindopril;Coversyl;Aceon, DSSTox_CID_24198, DSSTox_GSID_44198, SCHEMBL41679, SPECTRUM1505212, CHEMBL1200343, DTXSID1044198, HY-B0130A, Perindopril erbumine (JAN/USP), IYNMDWMQHSMDDE-MHXJNQAMSA-N, MolPort-003-666-611, HMS1922N07, HMS2093M06, Pharmakon1600-01505212, 107133-36-8 (erbumine), Tox21_303915, CCG-39035, CP0070, MFCD02313824, NSC758929, AKOS015841351, AKOS015961912, CS-1904, KS-1243, NSC-758929, NCGC00178276-01, NCGC00357164-01, AC-19078, LS-82690, AB0105687, AB2000130, AX8041142, TL8000252, CAS-107133-36-8, ST24048892, C07707, D00624, 133P368, SR-05000001835, SR-05000001835-1, Perindopril erbumine, United States Pharmacopeia (USP) Reference Standard, Perindopril tert-butylamine, European Pharmacopoeia (EP) Reference Standard, Perindopril for peak identification, European Pharmacopoeia (EP) Reference Standard, Perindopril for stereochemical purity, European Pharmacopoeia (EP) Reference Standard, (2S,3(infinity)S,7(infinity)S)-1-[(S)-N-[(S)-1-Carboxybutyl]alanyl]hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1), (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid; 2-methylpropan-2-amine, (2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid--2-methylpropan-2-amine (1/1), (2S,3aS,7aS)-1-{(S)-2-[(S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydroindole-2-carboxylic acid--1,1-dimethylethanamine (1/1), 1H-indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydo-, (2S-(1R(R*(R*)),2alpha,3abeta,7abeta))_,compd. With 2-methyl-2-propanamine (1:1)


ID: 1023

chemical graph of compound 1023



InChIKey: IYVFNTXFRYQLRP-VVSTWUKXSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5486699
synonyms found at PubChem are:
Troxerutin, 7085-55-4, Posorutin, Vitamin P4, Troxerutine, Vastribil, Veinamitol, Trioxyethylrutin, Factor P-zyma, Tris(hydroxyethyl)rutin, Veniten, Ruven, Venoruton P4, Tris(hydroxyethyl)rutoside, 3',4',7-Tris(hydroxyethyl)rutin, UNII-7Y4N11PXO8, Pherarutin, Troxerutin (INN), Trihydroxyethylrutin, Veno SL, Rufen-P4, Troksevazin, Troxarutin, Helveton, Venaroid, Flebil, 7Y4N11PXO8, Pur-Rutin, Veinamitol Pulver, Z 6000, Troxarutin-ratiopharm, Troxerutine [INN-French], Troxerutinum [INN-Latin], Troxerutina [INN-Spanish], Troxevazin, Troxerutin [INN:BAN:DCF], CCRIS 1798, Trihydroxyethylrutoside [French], Troxerutina, Troxerutinum, EINECS 230-389-4, 3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside, C33H42O19, BRN 4778232, 7,3',4'-Tris(O-(2-hydroxyethyl)rutin, Trihydroxyethylrutoside, Venoruton gel, TriHER, Troxerutin,(S), NCGC00095147-01, 2-(3,4-Bis(2-hydroxyethoxy)phenyl)-3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-7-(2-hydroxy ethoxy)-4H-1-benzopyran-4-one, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)methyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 3',4',7-Tris[O-(2-hydroxyethyl)]rutin, AC1NUOPY, DSSTox_CID_25929, DSSTox_RID_81230, DSSTox_GSID_45929, SCHEMBL142110, Tris-O-(2-hydroxyethyl)rutin, CHEMBL3182320, DTXSID4045929, Tris-O-(b-hydroxyethyl)rutoside, UNII-808O347B5Y, IYVFNTXFRYQLRP-VVSTWUKXSA-N, MolPort-003-939-710, Flavone, 3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-, 3-(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside), HY-N0139, Tox21_111450, s2369, ZINC85552699, AKOS016339659, Trihydroxyethylrutin, >=80% (HPLC), 808O347B5Y, CS-8204, DB13124, KS-1394, 4H-1-Benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-, K198, 3',4',7-Tri-O-(b-hydroxyethyl)rutoside, CAS-7085-55-4, O-(beta-hydroxyethyl)-tutinosides (mixture), 3,4,7-TRIS-O-(2-HYDROXYETHYL)RUTIN, D07180, rahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 085T554, A837010, BRD-K73529671-001-04-5, Troxerutin, European Pharmacopoeia (EP) Reference Standard, UNII-808O347B5Y component IYVFNTXFRYQLRP-VVSTWUKXSA-N, 12041-99-5, 1260230-02-1, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tet, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxymethyl]-2-oxanyl]oxy]-1-benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one, 2-[3,4-bis(2-hydroxyethyloxy)phenyl]-7-(2-hydroxyethyloxy)-3-[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-oxidanyl-chromen-4-one, 27321-15-9, 288306-51-4, 29702-52-1, 3-[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside]3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-Flavone, 3-[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-delta-glucopyranoside]3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-Flavone, 37396-63-7, 55965-63-4, 68244-17-7, 96304-71-1


ID: 1024

chemical graph of compound 1024



InChIKey: IYYZUPMFVPLQIF-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3S2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3023
synonyms found at PubChem are:
dibenzothiophene, 132-65-0, Diphenylene sulfide, Dibenzo[b,d]thiophene, 9-Thiafluorene, alpha-Thiafluorene, 2,2'-Biphenylylene sulfide, Dibenzo(b,d)thiophene, Dibenzothiophene [USAN], UNII-Z3D4AJ1R48, [1,1'-Biphenyl]-2,2'-diyl sulfide, .alpha.-Thiafluorene, CCRIS 5307, HSDB 7409, NSC 2843, EINECS 205-072-9, (1,1'-Biphenyl)-2,2'-diyl sulfide, AI3-00043, Z3D4AJ1R48, CHEBI:23681, IYYZUPMFVPLQIF-UHFFFAOYSA-N, NCGC00094646-01, Dibenzothiophene (USAN), benzo[b]benzo[b]thiophene, DSSTox_CID_27725, DSSTox_RID_82526, DSSTox_GSID_47741, a-thiafluorene, Dibenzothiophene, analytical standard, CAS-132-65-0, Dibenzthiophene, C12H8S, Dibenzo[b]thiophene, PubChem7382, Spectrum_000926, [1,2'-diyl sulfide, Dibenzothiophene, 98%, AC1L1EZZ, AC1Q1HKJ, Spectrum2_001011, Spectrum3_000383, Spectrum4_000504, Spectrum5_000863, Dibenzothiophene, >=99%, ACMC-1BQ37, SCHEMBL13294, BSPBio_002165, KBioGR_001047, KBioSS_001406, KSC174S9H, BIDD:GT0331, DivK1c_000393, SPECTRUM1500235, SPBio_001161, Dibenzothiophene, 98% 25g, CHEMBL219828, DTXSID0047741, CTK0H4993, HMS501D15, KBio1_000393, KBio2_001406, KBio2_003974, KBio2_006542, KBio3_001385, KS-00000ETF, NSC2843, MolPort-000-153-847, NINDS_000393, HMS1920E12, HMS2091K22, HMS3652N11, Pharmakon1600-01500235, HY-B0973, NSC-2843, ZINC1482032, Tox21_111308, Tox21_303415, ANW-19450, CCG-40229, MFCD00004969, NSC756732, s4205, SBB058907, STK367232, AKOS000278427, Tox21_111308_1, AC-1025, ACN-029847, CS-4462, MCULE-2582244078, NSC-756732, RP24479, RTC-070138, TRA0025307, IDI1_000393, NCGC00094646-02, NCGC00094646-03, NCGC00094646-04, NCGC00257449-01, AJ-26309, AN-15323, AS-12976, BC205510, BR-47299, CJ-05087, CJ-23638, KB-49718, LS-61504, SC-46601, SBI-0051339.P003, DB-042124, ST2412790, TL8000774, AM20050251, D0148, D2474, FT-0622967, ST50825219, Dibenzothiophene 10 microg/mL in Acetonitrile, C20125, D03777, M-4959, AB00051965_02, AB00051965_03, Dibenzothiophene, purified by sublimation, >=99%, SR-05000002089, I09-0207, Q-101161, SR-05000002089-1, Z1250100656, 8-thiatricyclo[7.4.0.0(2),]trideca-1(9),2(7),3,5,10,12-hexaene, 8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene, InChI=1/C12H8S/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8, 83R


ID: 1025

chemical graph of compound 1025



InChIKey: IZEKFCXSFNUWAM-UHFFFAOYSA-N
SMILES: C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3108
synonyms found at PubChem are:
dipyridamole, 58-32-2, Dipyridamine, Persantin, Dipyridamol, Dipyudamine, Persantine, Curantyl, Stimolcardio, Cardoxin, Kurantil, Stenocardil, Cardioflux, Dipiridamol, Dipyridan, Peridamol, Anginal, Apricor, Coribon, Corosan, Coroxin, Stenocardiol, Agilease, Chilcolan, Justpertin, Permiltin, Piroan, Cleridium 150, Coronarine, Gulliostin, Prandiol, Natyl, Prandiol 75, Usaf Ge-12, Dypyridamol, Cleridium, Iv Persantine, Dipyridamolum, Cardoxil, RA 8, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetraethanol, RA-8, Antistenocardin, Dipyramidole, Coridil, Curantil, Protangix, Novo-Dipiradol, Dipiridamol [INN-Spanish], Dipyridamolum [INN-Latin], Permole, Dipyridamole (Persantine), Persantine (TN), UNII-64ALC7F90C, Aggrenox, Apo-Dipyridamole Fc, Apo-Dipyridamole Sc, NSC 515776, MLS000028420, C24H40N8O4, Dipyridamole [USAN:INN:BAN:JAN], EINECS 200-374-7, CHEMBL932, NSC-515776, 2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido(5,4-d)pyrimidine, BRN 0068373, SMR000058382, 64ALC7F90C, CHEBI:4653, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol, IZEKFCXSFNUWAM-UHFFFAOYSA-N, Pyrimido(5,4-d)pyrimidine, 2,6-bis(bis(2-hydroxyethyl)amino)-4,8-dipiperidino-, NSC515776, Ethanol, 2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, CAS-58-32-2, NCGC00015385-12, 2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine, D 9766, 2,2',2'',2'''-((4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol, DSSTox_CID_20668, DSSTox_RID_79531, DSSTox_GSID_40668, 2,2',2'',2'''-((4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetrakis(ethan-1-ol), 2,2',2'',2'''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, Ethanol, 2,2',2'',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Cerebrovase, Dypyridamole, Miosen, 2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine, Apo-Dipyridamole, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetraethano, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, Ethanol, 2,2',2'',2'''-((4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetra-, SR-01000003065, Dipridacot, Prestwick_145, Dipyridamole [USAN:USP:INN:BAN:JAN], Spectrum_001004, Tocris-0691, Opera_ID_494, AC1Q7CXU, AC1Q7CXW, AC1Q7CXX, Prestwick0_000142, Prestwick1_000142, Prestwick2_000142, Prestwick3_000142, Spectrum2_000972, Spectrum3_000402, Spectrum4_000522, Spectrum5_000839, Lopac-D-9766, D0F9GE, UPCMLD-DP072, AC1L1F6T, cid_3108, Permole;Dipyridan;Persantine, Apotex Brand of Dipyridamole, Belmac Brand of Dipyridamole, IPRAD Brand of Dipyridamole, Lopac0_000464, SCHEMBL16119, BSPBio_000244, BSPBio_001554, BSPBio_001924, KBioGR_001123, KBioSS_001484, 4-26-00-03840 (Beilstein Handbook Reference), MLS001076306, MLS001333724, MLS002548866, DivK1c_000696, SPECTRUM1500259, SPBio_001003, SPBio_002183, Ashbourne Brand of Dipyridamole, BPBio1_000270, GTPL4807, Novopharm Brand of Dipyridamole, DTXSID6040668, Thymidine,6-dihydro-6-methoxy-, UPCMLD-DP072:001, BDBM23620, CTK8B5592, Dipyridamole (JP15/USP/INN), Dipyridamole (JP17/USP/INN), HMS502C18, IZEKFCXSFNUWAM-UHFFFAOYSA-, KBio1_000696, KBio2_001484, KBio2_004052, KBio2_006620, KBio3_001144, KS-00000KNA, MolPort-001-792-504, NINDS_000696, BCPP000256, HMS1568M06, HMS1791N16, HMS1920I10, HMS1989N16, HMS2089N15, HMS2091O18, HMS2095M06, HMS2232E19, HMS3259C03, HMS3261M10, HMS3266J17, HMS3371J03, HMS3402N16, HMS3655I20, HMS3712M06, Pharmakon1600-01500259, ZINC643046, BCP26947, Berlin Chemie Brand of Dipyridamole, Berlin-Chemie Brand of Dipyridamole, EBD20789, HY-B0312, Tox21_110133, Tox21_500464, ANW-49242, BBL027781, CCG-40190, MFCD00010555, NSC756743, s1895, STL377790, AKOS000509426, Tox21_110133_1, BCP9000613, CS-2352, DB00975, Dipyridamole, >=98% (TLC), powder, HS-0041, LP00464, MCULE-3112669573, MP-0582, NC00448, NSC-619103, NSC-756743, RTR-020274, VA10749, IDI1_000696, SMP2_000208, NCGC00015385-01, NCGC00015385-02, NCGC00015385-03, NCGC00015385-04, NCGC00015385-05, NCGC00015385-06, NCGC00015385-07, NCGC00015385-08, NCGC00015385-09, NCGC00015385-10, NCGC00015385-11, NCGC00015385-13, NCGC00015385-14, NCGC00015385-15, NCGC00015385-16, NCGC00015385-18, NCGC00023914-02, NCGC00023914-04, NCGC00023914-05, NCGC00023914-06, NCGC00023914-07, NCGC00023914-08, NCGC00023914-09, NCGC00023914-10, NCGC00023914-11, NCGC00261149-01, 4CA-0464, AC-18100, AJ-23813, AN-23600, BAS 00818792, BC213273, BR-76609, CJ-04389, CPD000058382, H843, LS-66732, NCI60_005689, SAM002264609, SC-18455, ST078856, ZB014732, Boehringer Ingelheim Brand of Dipyridamole, SBI-0050449.P004, 2,8-dipiperidinopyrimido[5,4-d]pyrimidine, AB0013300, AB2000355, ST2415551, AB00051974, B1933, D2274, EU-0100464, FT-0603242, Permole, Persantine, Dipyridan, Dipyridamole, W1467, EN300-70723, BIM-0050449.0001, D00302, J10379, 54290-EP2277865A1, 54290-EP2298773A1, 54290-EP2305653A1, 54290-EP2308562A2, AB00051974-18, AB00051974-19, AB00051974_20, AB00051974_21, 58-32-2,763-39-4(XHCl), A828156, SR-01000003065-2, SR-01000003065-4, SR-01000003065-5, SR-01000003065-7, W-105400, BRD-K86301799-001-04-1, BRD-K86301799-001-19-9, BRD-K86301799-001-24-9, Z1259192074, Dipyridamole, British Pharmacopoeia (BP) Reference Standard, Dipyridamole, European Pharmacopoeia (EP) Reference Standard, Dipyridamole, United States Pharmacopeia (USP) Reference Standard, Pyrimido(5, 2,6-bis[bis(2-hydroxyethyl)amino]-4,8-diperidino-, 2,2'',2'''-[4,8-Dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilotetraethanol, 2,2',2'',2'''-(4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilotetraethanol, 2,2',2',2'''-((4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol, 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-di(piperidin-1-yl)pyrimido[6,5-e]pyrimidin-, Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard, Ethanol,2',2'',2'''-(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetra-, WLN: T66 BN DN GN INJ CCN HCN E- AT6NTJ B2Q F2Q& J- AT6NTJ B2Q F2Q, 2,2 ,2 ,2 -(4,8-Dipiperidino- pyrimido [5,4-d] pyrimidine-2,6- diyldinitrilotetraethanol, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]-pyrimidine-2,6-diyl)bis(azanetriyl))tetraethanol, 2,2',2'',2'''-(4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl)tetraethanol, 2,2',2'',2'''-(4,8-Dipiperidino-pyrimido [5,4-d] pyrimidine-2,6-diyldinitrilotetraethanol, 2,2',2'',2'''-[(4,8-dipiperidin-1-ylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, 2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, 2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-dipiperidylpyrimidino[5,4-d]pyrimidin-2-y l}(2-hydroxyethyl)amino)ethan-1-ol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(1-piperidinyl)-6-pyrimido[5,4-d]pyrimidinyl]-(2-hydroxyethyl)amino]ethanol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol;, Ethanol, 2,2',2'',2'''-(4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyldinitrilo)tetra-, Ethanol, 2,2',2',2'''-((4,8-di-1-iperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Ethanol, 2,2',2',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Ethanol,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, Ethanol,2',2'',2'''-[(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-, Ethanol,2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, InChI=1/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2


ID: 1026

chemical graph of compound 1026



InChIKey: IZHCNQFUWDFPCW-ZJIMSODOSA-N
SMILES: C[C@H](CC1=CN=CN1)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957567
synonyms found at PubChem are:
75614-89-0, Histamine, R(-)-alpha-methyl-, dihydrochloride, (R)-1-(1H-Imidazol-4-yl)propan-2-amine dihydrochloride, R(-)-alpha-Methyl histamine dihydrochloride, 75614-87-8, Alpha-Methylhistamine-R, SR-01000075271, EU-0100618, SCHEMBL1369323, CHEMBL1434496, AOB5644, IZHCNQFUWDFPCW-ZJIMSODOSA-N, Tox21_500618, AKOS027320798, r-alpha-methylhistamine dihydrochloride, CCG-221922, LP00618, NCGC00093992-01, NCGC00261303-01, (R)(-)-|A-Methylhistamine dihydrochloride, FT-0671812, H-128, (R)(&#8722;)-|A-Methylhistamine dihydrochloride, SR-01000075271-1, (R)-(-)-a-Methyl-1H-imidazole-4-ethanamine dihydrobromide, (R)(-)-|A-Methyl-1H-imidazole-4-ethanamine dihydrochloride, (R)(-)-alpha-Methylhistamine dihydrochloride, solid, >=98% (HPLC)


ID: 1027

chemical graph of compound 1027



InChIKey: IZMYWEXQNFYSRZ-UHFFFAOYSA-N
SMILES: C1C2C(C(=O)N)=C(NC(C3CCCCC3)=O)SC=2CCC1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"GL Lukacs" "LJ Galietta" "A Taddei" "AS Verkman" "H Yang" "K Du" "AA Shelat" "C Folli" "VS Gopinath" "T Ma" "N Pedemonte" "RK Guy"


CID is 675676
synonyms found at PubChem are:
CHEMBL209562, 2-[(cyclohexylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 142995-02-6, 2-(cyclohexanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, AC1LDUWQ, Cambridge id 6993511, Oprea1_477124, ARONIS001749, SCHEMBL3126680, ZINC38517, IZMYWEXQNFYSRZ-UHFFFAOYSA-N, MolPort-001-501-026, BDBM50185103, STK095320, AKOS000491344, MCULE-4335105668, KS-00003V54, BAS 04054141, ST054630, BB0278962, EU-0008292, UNM000003541001, AK-968/12120287, SR-01000463330, SR-01000463330-1, Z27358490, 2-cyclohexaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(Cyclohexanecarbonyl-amino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid amide, 2-(cyclohexanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(cyclohexylcarbonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide


ID: 1028

chemical graph of compound 1028



InChIKey: IZQSVPBOUDKVDZ-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5281654
synonyms found at PubChem are:
Isorhamnetin, 480-19-3, 3-Methylquercetin, Isorhamnetol, Quercetin 3'-methyl ether, 3'-Methoxyquercetin, 3'-O-Methylquercetin, 3'-Methoxy-3,4',5,7-tetrahydroxyflavone, isorhamnetine, 3'-Methylquercetin, C.I. 75680, 3-Methylquercetine, UNII-07X3IB4R4Z, CCRIS 3791, 3,4',5,7-Tetrahydroxy-3'-methoxyflavone, 3'-O-Methyl Quercetin, C16H12O7, EINECS 207-545-5, Flavone, 3'-methoxy-3,4',5,7-tetrahydroxy-, BRN 0044723, 3,5,7,4'-Tetrahydroxy-3'-methoxyflavone, 07X3IB4R4Z, CHEBI:6052, CHEMBL379064, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3-methoxy-4-hydroxyphenyl)-3,5,7-trihydroxy-, FLAVONE, 3,4',5,7-TETRAHYDROXY-3'-METHOXY-, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, Q-100518, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one, iso-rhamnetin, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one, SR-05000002256, isorhamentin, Isorhanetin,(S), AC1NQYTP, 3,4',5,7-tetrahydroxy-3'-methoxy-flavone, D07YDN, Oprea1_145406, SCHEMBL19235, MEGxp0_001863, ACon1_000275, BDBM23409, CTK8E4477, Isorhamnetin, analytical standard, KS-00000JEU, DTXSID10197379, IZQSVPBOUDKVDZ-UHFFFAOYSA-N, MolPort-001-742-583, ZINC517261, BCP11534, HY-N0776, Isorhamnetin, >=95.0% (HPLC), CI-259, LMPK12110002, MFCD00017310, SBB067248, AKOS015905141, CCG-208422, CCG-208453, CS-5945, NCGC00163572-01, NCGC00163572-02, NCGC00163572-03, NCGC00180719-01, AC-20263, AN-45180, CC-29718, LS-69023, LS-69043, O276, SC-19267, ZB014262, 3,3',5,7-Tetrahydroxy-3'-methoxyflavone, TR-036851, FT-0603409, N1358, ST50309356, 3'-METHOXY-4',5,7-TRIHYDROXYFLAVONOL, C10084, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl), 480I193, C-19475, SR-05000002256-2, SR-05000002256-3, BRD-K83977206-001-01-4, Isorhamnetin, primary pharmaceutical reference standard, 3,5,7-Trihydroxy-2-(4-hydroxy-3-metoxyphenyl)benzopyran-4-one, Isorhamnetin, United States Pharmacopeia (USP) Reference Standard, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one #, 3 inverted exclamation marka-Methoxy-3,4 inverted exclamation marka,5,7-tetrahydroxyflavone, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)- (9CI)


ID: 1029

chemical graph of compound 1029



InChIKey: IZVFFXVYBHFIHY-SKCNUYALSA-N
SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 65728
synonyms found at PubChem are:
Lathosterol, gamma-Cholesterol, 80-99-9, Cholest-7-en-3-ol, 5alpha-Cholest-7-en-3beta-ol, 7-Cholesten-3-beta-ol, Cholesterin [German], Cholest-7-en-3beta-ol, delta(sup 7)-Cholestenol, 5-alpha-Cholest-7-en-3-beta-ol, Cholest-7-en-3-ol, (3b,5a)-, (3-beta,5-alpha)-Cholest-7-en-3-ol, CHEBI:17168, 7,(5-alpha)-Cholesten-3-beta-ol, 7-Cholesterol, .DELTA.7-Cholestenol, 7-Cholesten-3-.beta.-ol, 5|A-Cholest-7-en-3|A-ol, cholesterol gr, gamma-Cholestenol, cholesta-7-enol, cholest-7-en-ol, Cholesterol Pharma, (7)-Cholestenol, Delta7-Cholestenol, 3.beta.-Hydroxy-5.alpha.-cholest-7-ene, Cholesterol,NF Grade, 7-En-3-cholestanol, cholesterol extra pure, delta(7)-Cholestenol, Cholesterol - synthetic, 3b-Hydroxy-5-cholestene, delta7-Cholesten-3beta-ol, Delta7-cholesten-3-beta-ol, alpha-cholest-7-en-3beta-ol, SCHEMBL187737, (3beta)-Cholest-7-en-3-ol, 5-a-cholest-7-en-3-beta-ol, AC1L23U8, CHEMBL3138639, CTK3E8757, IZVFFXVYBHFIHY-SKCNUYALSA-N, 3|A-Hydroxy-5|A-cholest-7-ene, 3beta-Hydroxy-5alpha,7-cholestene, (3beta,alpha)-Cholest-7-en-3-ol, ZINC4095573, 3beta-Hydroxy-5alpha-cholest-7-ene, (3beta,5alpha)-cholest-7-en-3-ol, LMST01010089, MFCD00056176, (3|A,5|A)-Cholest-7-en-3-ol, AKOS024307570, KS-0000188D, LS-53132, Cholest-7-en-3-ol, (3-beta,5-alpha)-, FT-0631361, C01189, C-43996, Cholest-7-en-3-ol, (3-beta,5-alpha)- (9CI), (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol


ID: 1030

chemical graph of compound 1030



InChIKey: IZXSTWMUJGTAMI-UHFFFAOYSA-N
SMILES: CC(C)C1COC2=C(O1)C=C3C=CC(=O)OC3=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3503044
synonyms found at PubChem are:
DIHYDRO-OBLIQUIN, KBio1_001461, Spectrum_001781, SpecPlus_000421, AC1MQK3J, Spectrum2_000350, Spectrum3_000102, Spectrum4_001788, Spectrum5_000435, BSPBio_001684, KBioGR_002337, KBioSS_002263, SPECTRUM100543, DivK1c_006517, SPBio_000419, CHEMBL1610638, SCHEMBL12062091, CHEBI:91527, KBio2_002262, KBio2_004830, KBio2_007398, KBio3_000804, CCG-38625, SDCCGMLS-0066324.P001, NCGC00095430-01, NCGC00095430-02, BRD-A11483079-001-01-6, 2-isopropyl-2,3-dihydropyrano[2,3-g][1,4]benzodioxin-7-one, 2-propan-2-yl-2,3-dihydropyrano[2,3-g][1,4]benzodioxin-7-one


ID: 1031

chemical graph of compound 1031



InChIKey: JAABVEXCGCXWRR-UHFFFAOYSA-N
SMILES: C1CC2C3C(C1O2)C(=O)OC3=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 93004
synonyms found at PubChem are:
Norcantharidin, 5442-12-6, Endothall anhydride, Norcantharadine, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, 3,6-Endoxohexahydrophthalic anhydride, 29745-04-8, DEMETHYL-CANTHARIDIN, NSC 14003, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, FR-0742, 3,6-Endooxyphthalic anhydride, hexahydro-, Phthalic anhydride, hexahydro-3,6-endoxo-, C8H8O4, 4,10-dioxatricyclo[5.2.1.0<2,6>]decane-3,5-dione, NSC 59023, BRN 0084287, sodium norcantharidate, exo-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3a-alpha,4-beta,7-beta,7a-alpha)-, 3, hexahydro-, Norcantharidin, solid, Spectrum_001667, SpecPlus_000904, AC1L3PAJ, 4,3-dione, hexahydro-, Spectrum2_001683, Spectrum3_001634, Spectrum4_000601, Spectrum5_001514, D0S9QL, D0W4IL, CHEMBL8327, Lopac0_000830, BSPBio_003327, KBioGR_001122, KBioSS_002147, Phthalic anhydride,6-endoxo-, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, exo-, MLS002153470, DivK1c_007000, SCHEMBL177729, SPECTRUM1504153, SPBio_001606, norcantharidin, (3aalpha,4beta,7beta,7aalpha)-isomer, CTK5A0933, KBio1_001944, KBio2_002147, KBio2_004715, KBio2_007283, KBio3_002547, TIMTEC-BB SBB005955, JAABVEXCGCXWRR-UHFFFAOYSA-N, MolPort-001-508-621, HMS3262F21, HMS3370H07, 4,7-Epoxyisobenzofuran-1,3-dione, 51154-98-4, BCP09826, NSC14003, NSC59023, Tox21_500830, WLN: T C555 A AO DVOVTJ, CCG-39454, NSC-14003, NSC-59023, NSC148536, SBB005955, STK424286, Hexahydro-3,6-epoxyphthalic anhydride, AKOS003267901, AKOS022167759, FCH1677597, LP00830, MCULE-7561066553, NSC-148536, NCGC00015756-03, NCGC00015756-04, NCGC00015756-05, NCGC00015756-06, NCGC00015756-07, NCGC00015756-08, NCGC00015756-09, NCGC00094161-01, NCGC00094161-02, NCGC00094161-03, NCGC00094161-04, NCGC00094161-05, NCGC00094161-06, NCGC00261515-01, AN-11544, LS-98753, LS-98754, NCI60_001019, SC-14983, SMR000326693, ST057264, TR-019245, 4,4'-Diamino-2,4'-stilbenedisulfonic acid, EU-0100830, FT-0614776, FT-0621477, N1662, 4,7-Epoxyisobenzofuran-1,3-dione,hexahydro-, hexahydro-4,7-epoxy-2-benzofuran-1,3-dione, N 8784, SR-01000076037, I14-0105, SR-01000076037-1, BRD-A66914119-001-04-0, 4,10-Dioxa-tricyclo[5.2.1.02,6]decane-3,5-dione, EXO-7-OXA-BICYCLO(2.2.1)-HEPTANE-2,3-DICARBOXYLIC ANHYDRIDE


ID: 1032

chemical graph of compound 1032



InChIKey: JADDQZYHOWSFJD-FLNNQWSLSA-N
SMILES: CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 448222
synonyms found at PubChem are:
NECA, 35920-39-9, 5'-N-Ethylcarboxamidoadenosine, Adenosine-5'-(N-ethylcarboxamide), [3H]NECA, N-ethyl-5'-carboxamidoadenosine, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide, MLS000069759, CHEMBL464859, CHEBI:73284, [3H]adenosine-5'-(N-ethylcarboxamide), SMR000058759, N-Ethylcarboxamidoadenosine, 5'-N(Sup 6)-Ethylcarboxamidoadenosine, 5'-N-ETHYLCARBOXAMIDO-ADENOSINE, (2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, NEC, 5'-ethylcarboxamidoadenosine, 5'-Ethylcarboxamido Adenosine, Adenosine, N6-Ethyl-carboxamido, 2ydv, Adenosine analog, 3, 1qy5, Opera_ID_470, AC1L9LQM, D0K8ZZ, D0W1XA, GTPL377, GTPL425, 5'-Ethylcarboxamido-adenosine, MLS002153347, beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-, REGID_for_CID_448222, SCHEMBL16585523, BDBM21220, (2S,3S,4R)-5-(6-Aminopurin-9-yl)-N-ethyl-3,4-dihydroxy-oxolane-2-carboxamide, (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide, Adenosine-5-(N-ethylcarboxamide), JADDQZYHOWSFJD-FLNNQWSLSA-N, MolPort-023-276-191, HMS2234O07, ZINC3995401, MFCD00069195, AKOS024456749, CS-8131, NCGC00025260-02, NCGC00025260-03, NCGC00025260-04, NCGC00025260-05, 5'-(N-Ethylcarboxamido)adenosine, powder, AC-27392, SC-97607, HY-103173, 5 inverted exclamation mark -Ethylcarboxamido Adenosine, 5 inverted exclamation marka-N-ethylcarboxamidoadenosine, 5 inverted exclamation marka-(N-Ethylcarboxamido)adenosine, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-?-D-ribofuranuronamide, b-D-Ribofuranuronamide,1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-, 5''-N-Ethylcarboxamidoadenosine; D-NECA; NECAMolecular Formula: C12H16N6O4, 100111-00-0, 110282-65-0, 74992-42-0, 84272-21-9


ID: 1033

chemical graph of compound 1033



InChIKey: JALVTHFTYRPDMB-HRRTYWNUSA-N
SMILES: C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 101379
synonyms found at PubChem are:
Demissidine, Dihydrosolanidine, Demissidin, Solanidan-3beta-ol, UNII-VG66W0726Y, (3-beta,5-alpha)-Solanidan-3-ol, Solanidan-3-ol, (3beta,5alpha)-, EINECS 207-478-1, NSC 409074, (22R,25S)-5alpha-Solanidan-3beta-ol, (22S,25S)-5alpha-Solanidan-3beta-ol, 22R,25S-5alpha-Solanidanine-3beta-ol, 5-alpha-Solanidan-3-beta-ol, (22S,25S)-5-alpha-Solanidan-3-beta-ol, 5alpha-Solanidan-3beta-ol, (22R,25S)-, (22S,25S)-5-alpha-Solanidanine-3-beta-ol, (3beta,5alpha)-Solanidan-3-ol, 474-08-8, VG66W0726Y, Solanine D, Solanin D, AC1L2QPP, 5alpha-Solanidan-3beta-ol, SCHEMBL2683829, CHEMBL2165408, 5alpha-Solanidan-3beta-ol (8CI), LMST01150001, ZINC28539649, CCG-208467, Solanidan-3-ol, (3-beta,5-alpha)-, LS-145580, LS-145581, Solanidan-3-ol, (3-beta,5-alpha)- (9CI), SR-05000002229, SR-05000002229-2


ID: 1034

chemical graph of compound 1034



InChIKey: JAPHQRWPEGVNBT-UTUOFQBUSA-N
SMILES: C1CC(=C(N2[C@H]1[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5284585
synonyms found at PubChem are:
loracarbef, Lorabid, Loracarbefum, 76470-66-1, Loracarbef hydrate, UNII-W72I5ZT78Z, Loribid, Lorafem, KT 3777, Loracarbef monohydrate, LY-163892, W72I5ZT78Z, CHEBI:47544, Loracarbefum [INN-Latin], Lorabid (TN), KT-3777, LY163892, LY 163892, 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid, (6R,7S)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Loracarbef [USAN:INN:BAN], 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))-, Anhydrous loracarbef, Loracarbef (INN), Lorbef (TN), 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylate, 7beta-[(2R)-2-ammonio-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylate, (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7S)-7-{[(2R)-2-ammonio-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, D0E9WL, AC1NR4Q4, CHEMBL1013, LORACARBEF, ANHYDROUS, SCHEMBL34153, BIDD:GT0753, DTXSID7023223, CTK2H7568, JAPHQRWPEGVNBT-UTUOFQBUSA-N, HMS3713L04, 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R,7S)-, ZINC1530993, AKOS015895936, API0004680, CCG-220611, DB00447, D08143, I06-1267, BRD-K28935038-001-01-4, (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, (6R,7S)-, loracarbef zwitterion, CHEBI:214480


ID: 1035

chemical graph of compound 1035



InChIKey: JBEJXNWZBGTDKN-OJBGRLICSA-N
SMILES: C1C([C@H]([C@H](C(C1N)OC2[C@H]([C@H](C(C(O2)CN)O)O)N)OC3[C@H]([C@@H]([C@H](O3)CO)O)O)O)NC(=O)C(CCN)O.OS(=O)(=O)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6419880
synonyms found at PubChem are:
Butirosin disulfate salt, Prestwick_59, 51022-98-1, AC1O4WFO, HMS1570A21, 4-amino-N-[(2R,3R)-5-amino-4-[(3S,4R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-[(3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid


ID: 1036

chemical graph of compound 1036



InChIKey: JBGJVMVWYWUVOW-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C2=CC=CC=C2C=C1)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 69733
synonyms found at PubChem are:
711-79-5, 1'-Hydroxy-2'-acetonaphthone, 2-Acetyl-1-naphthol, 1-Hydroxy-2-acetylnaphthalene, 2-Acetyl-1-hydroxynaphthalene, Ethanone, 1-(1-hydroxy-2-naphthalenyl)-, 1-(1-hydroxynaphthalen-2-yl)ethanone, 1-Hydroxy-2-acetonaphthone, 1-(1-Hydroxy-2-naphthalenyl)ethanone, 2'-Acetonaphthone, 1'-hydroxy-, 1-Hydroxy-2-naphthyl methyl ketone, 3',4'-Benzo-2'-hydroxyacetophenone, UNII-N3BKY69086, 2-Aceto-1-naphthol, 1-(1-Hydroxy-naphthalen-2-yl)-ethanone, 1-(1-Hydroxy-2-naphthyl)ethanone, NSC 4973, JBGJVMVWYWUVOW-UHFFFAOYSA-N, N3BKY69086, Ethanone,1-(1-hydroxy-2-naphthalenyl)-, 1-(1-hydroxynaphthalen-2-yl)ethan-1-one, NSC4973, EINECS 211-918-8, ACMC-209ohj, AI3-00856, AC1L2CJH, alpha-Hydroxyacetonaphthone, AC1Q1JV9, AC1Q5GK9, 1-Hydroxy-2-acetonaphthalene, SCHEMBL431650, CHEMBL569194, DTXSID4061044, CTK5D3650, MolPort-001-759-193, ZINC154709, KS-00000V0J, NSC-4973, 1-(1-Hydroxy-2-naphthyl) Ethanone, 8552AE, ANW-36005, BBL012750, SBB010063, STK070535, 1'-Hydroxy-2'-acetonaphthone, 99%, 1-(1-Hydroxy-2-naphthyl)ethanone #, AKOS000119758, 1-(1-hydroxy-2-naphthyl)-1-ethanone, MCULE-2060868197, NE10287, VZ20794, 2'-Acetonaphthone, 1'-hydroxy- (8CI), KB-66268, SC-22278, ZB005859, DB-055504, TL8006622, TR-044006, BB 0261365, FT-0607920, ST50331808, 2-(1-Hydroxyethylidene)naphthalene-1(2H)-one, I01-10424, InChI=1/C12H10O2/c1-8(13)10-7-6-9-4-2-3-5-11(9)12(10)14/h2-7,14H,1H


ID: 1037

chemical graph of compound 1037



InChIKey: JBGKVNQFVAJOGC-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C(=C1)C=C3C=CC=C(C3=C2O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 10288
synonyms found at PubChem are:
3-Methylanthralin, 3-Methyl-1,8,9-anthracenetriol, Purified araroba, 491-59-8, Chrysophanic acid anthranol, 1,8,9-Anthracenetriol, 3-methyl-, UNII-0433FJV3CI, 1,8,9-Trihydroxy-3-methylanthracene, CCRIS 5597, 1,8-Dihydroxy-3-methylanthron, 3-Methyl-1,8,9-trihydroxyanthracene, BRN 2124735, AI3-62089, 0433FJV3CI, 3-methylanthracene-1,8,9-triol, JBGKVNQFVAJOGC-UHFFFAOYSA-N, 3-Methyl-1,8-dihydroxy-9,10-dihydro-9-oxoanthracen, NCGC00181774-01, DSSTox_CID_28597, DSSTox_RID_82868, DSSTox_GSID_48671, CAS-491-59-8, Purified goa powder, Chrysophansaureanthranol, AC1L1UVW, AC1Q7AY4, 4-06-00-07604 (Beilstein Handbook Reference), SCHEMBL5858623, CHEMBL2135835, DTXSID1048671, CTK4J1116, Tox21_113041, 2C15H12O3, ACM491598, AKOS030530690, Tox21_113041_1, ZINC100090070, NCGC00181774-02, CJ-32387, LS-20394, LS-187737, FT-0632219


ID: 1038

chemical graph of compound 1038



InChIKey: JBJYTZXCZDNOJW-JLHYYAGUSA-N
SMILES: COC1=CC(=C(C(=C1)OC)/C=C/2\C3=CC=CC=C3NC2=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5288600
synonyms found at PubChem are:
ic261, IC 261, 3-[(2,4,6-Trimethoxyphenyl)methylidenyl]-indolin-2-one, SU5607, 186611-52-9, CHEMBL489156, SU-5607, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, 3-(2,4,6-trimethoxybenzylidene)indolin-2-one, (3E)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one, 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one, IC1, AC1NRBRK, Lopac-I-0658, Lopac0_001017, SCHEMBL2786157, MolPort-002-894-454, HMS1433C06, HMS3229I10, HMS3263K15, ZINC136945, Tox21_501017, BDBM50263829, HSCI1_000024, MFCD00118156, s8237, AKOS030632794, CCG-205097, CS-4967, DB03083, LP01017, SU5607 (IC261), IDI1_012141, NCGC00015546-01, NCGC00015546-02, NCGC00015546-03, NCGC00015546-04, NCGC00094309-01, NCGC00094309-02, NCGC00261702-01, HY-12774, EU-0101017, I 0658, SR-01000075566, J-011989, SR-01000075566-1, BRD-K09638361-001-01-4


ID: 1039

chemical graph of compound 1039



InChIKey: JBMKAUGHUNFTOL-UHFFFAOYSA-N
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2720
synonyms found at PubChem are:
chlorothiazide, 58-94-6, Diuril, Chlorthiazide, Chlorothiazid, Chlotride, Chlortiazid, Thiazide, Chlorosal, Chlorurit, Saluretil, Warduzide, Alurene, Clotride, Diuresal, Diurilix, Diurite, Diutrid, Salisan, Salunil, Saluric, Yadalan, Flumen, Minzil, Urinex, Neo-Dema, Chlorothiazidum, Sk-chlorothiazide, Chlorthiazid, Chlorthiazidum, Clorotiazida, Aldoclor, Diupres, Clorotiazide, Chloriazid, Chlrosal, Clorotiazide [DCIT], Diuril Boluses, Diuril Boluses, Veterinary, 6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Clorotiazida [INN-Spanish], Chlorothiazidum [INN-Latin], component of Aldoclor, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide, 6-Chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, C7H6ClN3O4S2, NSC 25693, Diuril (TN), CCRIS 5999, UNII-77W477J15H, Chlorothiazide [USAN:INN:BAN], HSDB 3030, EINECS 200-404-9, MLS000028398, CHEBI:3640, Chlorothiazide (JAN/USP/INN), JBMKAUGHUNFTOL-UHFFFAOYSA-N, NSC25693, 77W477J15H, CAS-58-94-6, NCGC00015242-04, SMR000058429, 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, DSSTox_CID_2800, C 4911, DSSTox_RID_76733, DSSTox_GSID_22800, 6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, SR-01000075604, chlorotiazida, Mechlozid, 6-chloro-1,1-dioxo-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Diuril;Chlotride, Chlorothiazide [USP:INN:BAN], Prestwick_56, Diupres (Salt/Mix), Aldoclor (Salt/Mix), Spectrum_000134, AC1L1EBB, Prestwick0_000251, Prestwick1_000251, Prestwick2_000251, Prestwick3_000251, Spectrum2_000154, Spectrum3_000342, Spectrum4_000280, Spectrum5_001446, Lopac-C-4911, CHEMBL842, D0M9WM, cid_2720, Lopac0_000254, SCHEMBL22329, BSPBio_000062, BSPBio_002003, KBioGR_000780, KBioSS_000594, BIDD:GT0635, DivK1c_000675, SPECTRUM1500180, SPBio_000288, SPBio_002281, BPBio1_000070, GTPL4835, CHEMBL3392493, DTXSID0022800, BDBM39351, Chlorothiazide, thiazide diuretic, CTK8F8613, HMS502B17, KBio1_000675, KBio2_000594, KBio2_003162, KBio2_005730, KBio3_001223, Diuril, Chlotride, Chlorothiazide, MolPort-003-666-143, MolPort-003-845-912, NINDS_000675, HMS1568D04, HMS1920K15, HMS2091C18, HMS2095D04, HMS2232N22, HMS3259K15, HMS3260D10, HMS3370A15, HMS3655M13, HMS3712D04, Pharmakon1600-01500180, BCP24474, HY-B0224, KS-00001F6W, ZINC3872055, Tox21_110107, Tox21_200972, Tox21_500254, WLN: T66 BSWM ENJ HG ISZW, CCG-38953, LS-244, MFCD00058576, NSC-25693, NSC756682, s1641, AKOS015896601, AKOS024319450, Tox21_110107_1, CS-2171, DB00880, LP00254, MCULE-3497410863, NC00500, NSC-756682, IDI1_000675, NCGC00015242-01, NCGC00015242-02, NCGC00015242-03, NCGC00015242-05, NCGC00015242-06, NCGC00015242-07, NCGC00015242-08, NCGC00015242-09, NCGC00015242-10, NCGC00015242-12, NCGC00015242-13, NCGC00091042-01, NCGC00091042-02, NCGC00091042-03, NCGC00091042-04, NCGC00091042-05, NCGC00258525-01, NCGC00260939-01, AC-18732, AN-10251, AS-11760, CPD000058429, SAM002554891, SC-45427, ACM1189440796, SBI-0050242.P004, AB0010688, AB2000186, EU-0100254, FT-0602975, C07461, D00519, AB00051940-04, AB00051940_05, AB00051940_06, 102632-EP2270011A1, 102632-EP2272841A1, 102632-EP2277879A1, 102632-EP2298776A1, 102632-EP2301936A1, I06-2278, SR-01000075604-1, SR-01000075604-3, SR-01000075604-5, W-105353, BRD-K88682005-001-05-9, BRD-K88682005-001-07-5, Z1691545266, 6-Chloro-7-sulfamoyl-2H-1,4-benzothiadiazine 1,1-dioxide, 6-Chloro-2H-1,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Chlorothiazide, European Pharmacopoeia (EP) Reference Standard, 2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-, 1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide, 6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-4H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, Chlorothiazide, United States Pharmacopeia (USP) Reference Standard, Chlorothiazide, Pharmaceutical Secondary Standard; Certified Reference Material


ID: 1040

chemical graph of compound 1040



InChIKey: JBTQLUUOBPYIPP-FMLJXKFRSA-N
SMILES: C[C@]12CC[C@@H](C[C@@H]1CCC3C2CC[C@]4(C3CCC4=O)C)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708555
synonyms found at PubChem are:
Spectrum_000669, 3beta-chloroandrostanone, SpecPlus_000100, Spectrum2_000363, Spectrum3_000120, Spectrum4_001399, Spectrum5_000138, AC1O8FD1, BSPBio_001740, KBioGR_001758, KBioSS_001149, SPECTRUM100586, DivK1c_006196, SPBio_000485, KBio1_001140, KBio2_001149, KBio2_003717, KBio2_006285, KBio3_000880, CCG-39729, NCGC00179042-01, (3S,5S,10S,13S)-3-chloro-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one


ID: 1041

chemical graph of compound 1041



InChIKey: JCBIVZZPXRZKTI-UHFFFAOYSA-N
SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 12947
synonyms found at PubChem are:
HYDROXYCHLOROQUINE SULFATE, 747-36-4, Hydroxychloroquine sulphate, Ercoquin, Plaquinol, Toremonil, 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate, Hydroxychloroquine sulfate [USP], TCMDC-123987, EINECS 212-019-3, Plaquenil (TN), AI3-52706, NSC 4375, DSSTox_CID_27788, hydroxychloroquine; sulfuric acid, 2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), AK-72909, DSSTox_RID_82563, Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt), C18H28ClN3O5S, DSSTox_GSID_47811, W-104413, 2-((4-((7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol sulfate, (+-)-2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol; sulfuric acid, CAS-747-36-4, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethyl)amino-, (+-)-, sulfate (1:1) salt, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1), SR-05000001881, NCGC00159483-02, C18H26ClN3O.H2O4S, Plaquenil sulfate, 2-((4-(7-chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol sulfate, 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid, 7-Chloro-4-[4-[ethyl-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline, HCQ sulfate, Ethanol, monosulfate, Oxichlorochine Sulfate, PubChem15393, AC1L20PB, CHEMBL1690, SCHEMBL41114, SPECTRUM1503978, HYDROXYCHLOROQINE SULFATE, 118-42-3 (Parent), DTXSID1047811, Hydroxychloroquine Sulfate ,(S), CTK8B4131, KS-00000GEU, MolPort-003-666-519, Ethanol, sulfate (1:1) (salt), HMS1922O12, HMS2093O05, HMS3713J22, Pharmakon1600-01503978, BCP12823, HY-B1370, NSC-4375, Tox21_111707, ANW-43969, CCG-39154, NSC758663, s4430, Hydroxychloroquine sulfate (JAN/USP), AKOS015897337, Tox21_111707_1, API0025948, CS-8017, KS-5311, MCULE-4122662001, NSC-758663, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt), NCGC00095090-01, NCGC00095090-02, NCGC00159483-04, AN-22118, BR-72909, CPD000525253, LS-66615, M567, SAM001246735, ACM1216432562, AB0015282, AX8134190, KB-219927, TR-024132, 4CH-007360, FT-0603511, ST24030764, Hydroxycloroquine sulfate, analytical standard, D02114, J10260, S-2011, 747H364, Hydroxychloroquine sulfate, >=98% (HPLC), powder, SR-05000001881-1, SR-05000001881-2, Z1551900864, Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base), 2-((4-((7-Chloroquinolin-4-yl)amino)-pentyl)(ethyl)amino)ethanol sulfate, 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate, 2-[4-[(7-chloro-4-quinolyl)amino]pentyl-ethyl-amino]ethanol; sulfuric acid, 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol; sulfuric acid, 7-Chloro-4-[4-[N-ethyl-N-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline Sulfate, Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material, Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard, N4-(7-Chloro-4-quinolyl)-N1-ethyl-N1-(2-hydroxyethyl)-1,4-pentanediamine Sulfate, Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) (8CI)


ID: 1042

chemical graph of compound 1042



InChIKey: JCCNYMKQOSZNPW-UHFFFAOYSA-N
SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3957
synonyms found at PubChem are:
loratadine, 79794-75-5, Claritin, Loratidine, Alavert, Clarityn, Lisino, Clarityne, Loracert, Loradex, Bonalerg, Claritine, Fristamin, Histaloran, Lertamine, Lorastine, Loratyne, Civeran, Loranox, Versal, Allertidin, Polaratyne, Aerotina, Alerpriv, Anhissen, Biloina, Claratyne, Clarinase, Lesidas, Loradif, Lorantis, Loraver, Lorfast, Loritine, Lowadina, Nularef, Optimin, Restamine, Rhinase, Rinomex, Sanelor, Sensibit, Sohotin, Velodan, Alarin, Lergy, Pylor, Tadine, Zeos, Sinhistan Dy, Bedix Loratadina, Talorat Dy, Claritin Reditabs, Clarinase Reperabs, Loratadina, Loratadinum, Loratadinum [Latin], Claratyne Cold, Claritin reditab, Loratadina [Spanish], Clarityne-D, Sch 29851, Sch-29851, Children's Claritin, Clarium, Claratyne Decongestant, Clarityne Dy Repetabs, Claritin D, Loratadine Redidose, Claritin Hives Relief, Roletra, UNII-7AJO3BO7QN, ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate, Claritin (TN), Claritin Hives Relief Reditab, Loratadine [USAN:BAN:INN], HSDB 3578, 7AJO3BO7QN, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate, CHEMBL998, C22H23ClN2O2, Loratadine (JAN/USAN/INN), MLS000069647, JCCNYMKQOSZNPW-UHFFFAOYSA-N, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester, NCGC00015619-09, SMR000058255, DSSTox_CID_3224, L 9664, DSSTox_RID_76931, DSSTox_GSID_23224, 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester, Bactimicina allergy, 1-piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-,ethyl ester, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cycloheptal[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate, ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, CAS-79794-75-5, SR-01000075968, Cronopen, Flonidan, Klaritin, Sch29851, Alavert;Claritin, Topcare childrens allergy relief, Loratadine,(S), Claritine (TN), Clarityne (TN), Fristamin (TN), Loratadine [USAN:USP:INN:BAN], Symphoral (TN), Clarityn (TN), Flonidan (TN), Alavert (TN), AllergyX (TN), Lomilan (TN), Lorfast (TN), Rinolan (TN), Roletra (TN), Tidilor (TN), Loratadine Wyeth Brand, Spectrum_001496, Tocris-1944, Opera_ID_1868, Spectrum2_001584, Spectrum3_000740, Spectrum4_000177, Spectrum5_001650, Lopac-L-9664, Wyeth Brand of Loratadine, D06ABF, AC1L1H3E, SCHEMBL4596, Lopac0_000680, Oprea1_027965, REGID_for_CID_3957, BSPBio_002300, KBioGR_000693, KBioSS_001976, MLS000758260, MLS001148466, MLS001423984, Alavert, Claritin, Loratadine, BIDD:GT0198, DivK1c_000792, SPECTRUM1503712, SPBio_001548, CHEBI:6538, GTPL7216, DTXSID2023224, BDBM22876, CTK8G0633, HMS502H14, KBio1_000792, KBio2_001976, KBio2_004544, KBio2_007112, KBio3_001520, KS-00000JOZ, MolPort-002-507-846, NINDS_000792, HMS2051G11, HMS2090O18, HMS2093I15, HMS2235G23, HMS3262G21, HMS3268M16, HMS3371D13, HMS3393G11, HMS3654L17, HMS3714E09, Pharmakon1600-01503712, ZINC537931, Loratadine 0.1 mg/ml in Methanol, ACT04775, BCP22338, Tox21_110185, Tox21_301532, Tox21_500680, BBL010757, CCG-39362, CL0028, DL-436, FC1275, HTS028367, MFCD00672869, NSC721075, NSC758628, s1358, STK574925, AKOS005499513, Loratadine, >=98% (HPLC), powder, Tox21_110185_1, AB06849, AC-2086, BCP9000858, CCG-100786, CS-0887, DB00455, KS-1079, LP00680, MCULE-5073177964, NC00036, NSC-721075, NSC-758628, IDI1_000792, NCGC00015619-01, NCGC00015619-02, NCGC00015619-03, NCGC00015619-04, NCGC00015619-05, NCGC00015619-06, NCGC00015619-07, NCGC00015619-08, NCGC00015619-10, NCGC00015619-11, NCGC00015619-12, NCGC00015619-13, NCGC00023125-02, NCGC00023125-04, NCGC00023125-05, NCGC00023125-06, NCGC00023125-07, NCGC00255171-01, NCGC00261365-01, AJ-23376, AN-14336, CPD000058255, HY-17043, NCI60_041473, SAM001246987, SC-13436, ZB014352, BCP0726000007, SBI-0050659.P003, AB0012486, AB2000066, LS-114660, ST2413201, TL8005389, EU-0100680, FT-0627976, L0223, D00364, J10034, M-5196, AB00053224-15, AB00053224-16, AB00053224_17, AB00053224_18, 794L755, L000667, I14-0747, Q-100833, SR-01000075968-1, SR-01000075968-3, SR-01000075968-4, SR-01000075968-6, BRD-K82795137-001-02-3, BRD-K82795137-001-10-6, Z1741979837, Loratadine, European Pharmacopoeia (EP) Reference Standard, Loratadine, United States Pharmacopeia (USP) Reference Standard, Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material, Loratadine for system suitability, European Pharmacopoeia (EP) Reference Standard, 1-Piperidenecarboxylic acid, 4-(8-chloro-5,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester, 1-Piperidenecarboxylic acid,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester, 11-[N-(ethoxycarbonyl)-4-piperidylidene]-8-chloro-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]pyridine, 4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE, 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acidethyl ester, 4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester, 4-(8-chloro-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester, 8-chloro-11-(1-ethoxycarbonyl-4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1- ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-Chloro-6,11-dihydro-11-(1-ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, ETHYL 4-(13-CHLORO-4-AZATRICYCLO[9.4.0.0(3,8)]PENTADECA-1(11),3(8),4,6,12,14-HEXAEN-2-YLIDENE)PIPERIDINE-1-CARBOXYLATE, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidine)-1-piperidinecarboxylate, ethyl 4-(8-chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0(3),]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0;{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, loratadine impurity c;4-(4,8-dichloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester


ID: 1043

chemical graph of compound 1043



InChIKey: JCDRZCWRRLKLTB-UHFFFAOYSA-N
SMILES: CNCCC1=CC(=C(C=C1)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 86470
synonyms found at PubChem are:
N-Methyldopamine hydrochloride, 62-32-8, Epinine hydrochloride, Ephinine hydrochloride, Methyldopamine hydrochloride, Deoxyepinephrine hydrochloride, UNII-ZV3MG8PAX3, N-Methyldopamine HCl, EINECS 200-528-3, ZV3MG8PAX3, 3,4-Dihydroxyphenylethylmethylamine hydrochloride, 4-(2-Methylaminoethyl)pyrocatechol hydrochloride, NSC 294897, 3,4-Dihydroxyphenyl-1-methylamino-2-ethane hydrochloride, 3,4-Dihydroxyphenethylmethylammonium chloride, deoxyepinephrine, EPININE HCl, 4-(2-(Methylamino)ethyl)benzene-1,2-diol hydrochloride, 4-[2-(methylamino)ethyl]benzene-1,2-diol hydrochloride, Methyl-(beta-(3,4-dihydroxyphenyl)ethyl)amine hydrochloride, Pyrocatechol, 4-(2-(methylamino)ethyl)-, hydrochloride, Pyrocatechol, 4-[2-(methylamino)ethyl]-, hydrochloride, Methyldopamine HCl, SMR000326768, 4-[2-(Methylamino)ethyl]-1,2-benzenediol, AC1L3BMB, AC1Q3F7D, N-Methyldopaminehydrochloride, MLS000859907, MLS001332603, MLS001332604, N-Methyl Dopamine Hydrochlorie, N-methyl dopamine hydrochloride, SCHEMBL1320882, CHEMBL1256484, CTK8C5228, WLN: QR BQ D2M1 &GH, 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-hydrochloride, DTXSID90211027, JCDRZCWRRLKLTB-UHFFFAOYSA-N, MolPort-001-757-325, 1,2-Benzenediol, 4-(2-(methylamino)ethyl)-, hydrochloride, ZX-AT001333, Tox21_500390, ANW-74853, KM0599, MFCD00035074, NSC294897, OR1575, SBB093199, 4-[2-(Methylamino)ethyl]pyrocatechol, AKOS015965249, CCG-221694, LP00390, MTB0000346, NSC-294897, PS-8162, Deoxyepinephrine hydrochloride crystalline, NCGC00093818-01, NCGC00261075-01, AC-20364, KB-58534, AX8145089, DB-001742, LS-136446, TC-163598, EU-0100390, FT-0650241, Methyl[b-(3,4-dihydroxyphenyl) ethyl] amine, 1, 4-[2-(methylamino)ethyl]-, hydrochloride, 3,4-Dihydroxyphenylethylmethyamine hydrochloride, D 5886, N-Methyl-3,4-hydroxyphenethylamine hydrochloride, C-45961, SR-01000075369, Epinine hydrochloride; Deoxyepinephrine hydrochloride, SR-01000075369-1, 4-[2-(methylamino)ethyl]benzene-1,2-diol, chloride, 4-[2-(methylamino)ethyl]-1,2-benzenediol hydrochloride, 4-[2-(Methylamino)ethyl]benzene-1,2-diol hydrochlorid, 4-[2-(methylamino)ethyl]benzene-1,2-diol,hydrochloride, Methyl-[.beta.-(3,4-dihydroxyphenyl)ethyl]amine hydrochloride, 1,2-Benzenediol, 4-(2-(methylamino)ethyl)-, hydrochloride (9CI)


ID: 1044

chemical graph of compound 1044



InChIKey: JCKYGMPEJWAADB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2708
synonyms found at PubChem are:
chlorambucil, 305-03-3, Ambochlorin, Chloroambucil, Leukeran, Chloraminophen, Chlorbutin, Chloraminophene, Chlorobutine, Amboclorin, Chlorbutine, Chlorobutin, Linfolizin, Linfolysin, Ecloril, Elcoril, Phenylbutyric acid nitrogen mustard, Lympholysin, Chlocambucil, Leukersan, Leukoran, Chloorambucol, Chlorbutinum, Elcorin, 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid, Cb l348, Chlorambucilum, Clorambucile, Clorambucilo, Clorambucile [DCIT], CB 1348, Phenylbuttersaeure-lost, Leukeran tablets, NSC 3088, NSC-3088, Rcra waste number U035, NCI-C03485, Chlorambucilum [INN-Latin], Clorambucilo [INN-Spanish], 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid, Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, N,N-Di-2-chloroethyl-gamma-p-aminophenylbutyric acid, Leuk ersan, Chlorambucil [INN:BAN], 4-(p-Bis(beta-chloroethyl)aminophenyl)butyric acid, CCRIS 126, 4-(Bis(2-chloroethyl)amino)benzenebutanoic acid, p-(N,N-Di-2-chloroethyl)aminophenyl butyric acid, UNII-18D0SL7309, CHEBI:28830, Phenylbuttersaeure-lost [German], HSDB 3026, NSC3088, LEUKERAN (TN), EINECS 206-162-0, 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, CHEMBL515, RCRA waste no. U035, gamma-[p-Di(2-chloroethyl)aminophenyl]butyric acid, CB-1348, 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid, Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-, BRN 0999011, AI3-26083, MLS000028443, 4-(Bis(2-chloroethyl)amino)phenylbutyric acid, 4-[Bis(2-chloroethyl)amino]benzenebutyric acid, 4-[Bis(2-chloroethyl)aminophenyl]butyric acid, JCKYGMPEJWAADB-UHFFFAOYSA-N, p-(N,N-Di-2-chlorethylaminophenyl)butyric acid, para-(Di(2-chloroethyl)aminophenyl)butyric acid, gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid, 4-(p-(Bis(2-chloroethyl)amino)phenyl)butyric acid, Butanoic acid, 4-(bis(2-chloroethyl)amino) benzene, gamma-(p-Bis(2-chloroethyl)aminophenyl)butyric acid, gamma-(p-Di(2-chloroethyl)aminophenyl)butyric acid, Butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)-, p-N,N-Di-(beta-chloroethyl)aminophenyl butyric acid, Butyric acid, 4-(p-(bis(2-chloroethyl)amino)phenyl), para-N,N-Di(beta-chloroethyl)aminophenyl butyric acid, 18D0SL7309, Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna, N,N-Di-2-chloroethyl-gamma-para-aminophenyl butyric acid, NCGC00015199-08, CAS-305-03-3, SMR000058372, DSSTox_CID_263, Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna [Czech], 4-[Bis(2-chloroethyl)amino]phenylbutyric acid, chlorambucil,4-bis(2-chloroethyl)amino]benzenebutanoic acid, n,n-di-2-chloroethyl-, DSSTox_RID_75472, DSSTox_GSID_20263, 4-(4-(Bis(2-chloroethyl)amino)phenyl)butanoic acid, W-106940, .gamma.-[p-Di(2-chloroethyl)aminophenyl]butyric acid, 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid, Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]-, p-N,N-Di-(.beta.-chloroethyl)aminophenyl butyric acid, 4-(p-[bis-(2-Chloroethyl)-amino]-phenyl)-butyric acid, N,N-Di-2-chloroethyl-.gamma.-p-aminophenylbutyric acid, SR-01000000062, 4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid, 4-[4-[Bis(2-chloroethyl)amino]phenyl]butyric Acid, .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acid, .gamma.-[p-bis(2-chloroethyl)aminophenyl]butyric acid, 4-(p-Bis(.beta.-chloroethyl)aminophenyl)butyric acid, 4-[p-Bis(.beta.-chloroethyl)aminophenyl]butyric acid, Butyric acid, 4-(p-[bis(2-chloroethyl)amino]phenyl)-, Chlorambucil [USP:INN:BAN], Chlorambucil,(S), phenyl)butanoic acid, CB1348, Opera_ID_51, PubChem21331, Spectrum_000118, AC1L1EAB, Prestwick0_001079, Prestwick1_001079, Prestwick2_001079, Prestwick3_001079, Spectrum2_000065, Spectrum3_000336, Spectrum4_000273, Spectrum5_000677, Chlorambucil (USP/INN), Lopac-C-0253, D0V8QT, Epitope ID:139977, AC1Q75DO, SCHEMBL4308, Lopac0_000227, WLN: QV3R DN2G2G, BSPBio_001098, BSPBio_001971, KBioGR_000766, KBioSS_000558, 4-14-00-01715 (Beilstein Handbook Reference), MLS001076130, DivK1c_000688, SPECTRUM1500171, Chlorambucil (JAN/USP/INN), SPBio_000249, SPBio_002999, Wellcome Brand of Chlorambucil, Phenylbuttersaeure-lost[German], BPBio1_001208, GTPL7143, ZINC1115, DTXSID7020263, CTK8E8346, HMS502C10, KBio1_000688, KBio2_000558, KBio2_003126, KBio2_005694, KBio3_001191, MolPort-000-152-694, NINDS_000688, HMS1571G20, HMS1920M15, HMS2090M19, HMS2091A22, HMS2098G20, HMS2235A04, HMS3259I10, HMS3372O04, HMS3652P08, Pharmakon1600-01500171, 4-(4-(bis(2-chloroethyl)amino), BCP28394, Tox21_110096, Tox21_201390, Tox21_302996, BDBM50003677, CCG-39872, Glaxo Wellcome Brand of Chlorambucil, GlaxoSmithKline Brand of Chlorambucil, GP0879, MFCD00021783, NSC756674, s4288, AKOS024319346, Tox21_110096_1, API0003150, Chlorambucil, purum, >=98.0% (T), CS-3118, DB00291, GS-6200, LP00227, LS-1158, MCULE-2575006904, NC00555, NSC-756674, IDI1_000688, NCGC00015199-01, NCGC00015199-02, NCGC00015199-03, NCGC00015199-04, NCGC00015199-05, NCGC00015199-06, NCGC00015199-07, NCGC00015199-09, NCGC00015199-10, NCGC00015199-11, NCGC00015199-12, NCGC00015199-13, NCGC00015199-14, NCGC00015199-15, NCGC00015199-16, NCGC00015199-17, NCGC00015199-19, NCGC00015199-20, NCGC00023250-00, NCGC00023250-03, NCGC00023250-04, NCGC00023250-05, NCGC00023250-06, NCGC00023250-07, NCGC00023250-08, NCGC00023250-09, NCGC00023250-10, NCGC00256464-01, NCGC00258941-01, AN-16019, BC208809, BP-24028, CC-25645, CPD000058372, HY-13593, KB-48833, NCI60_002639, SAM002564202, SC-16653, SC-54759, SBI-0050215.P004, AB0093202, TL8002353, TR-013105, AB00051938, EU-0100227, FT-0083565, FT-0617365, ST50410766, KS-00001815, A18607, C 0253, C06900, D00266, 4-(p-bis(2-chloroethyl)aminophenyl)butyric acid, AB00051938-14, AB00051938-15, AB00051938_16, 305C033, 4-((p-bis(b-chloroethyl)amino)phenyl)butyric acid, C-18948, 4[p-Bis(.beta.-chloroethyl)aminophenyl]butyric acid, Butanoic acid, 4-(bis(2-chloroethyl)amino)benzene-, SR-01000000062-2, SR-01000000062-4, SR-01000000062-7, .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyricacid, BRD-K29458283-001-04-2, BRD-K29458283-001-05-9, BRD-K29458283-001-17-4, 4-(4-[Bis(2-chloroethyl)amino]phenyl)butanoic acid #, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)buty ric acid, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid, Z1558572529, 4-[4-(N,N-bis(2-chloroethyl)-amino]phenyl)butanoic acid, ETHANAMINE,2-[[4-(1-METHYLETHOXY)PHENYL]SULFONYL]-, N,N-Di-(2-chloroethyl)-gamma-(p-aminophenyl)butyric acid, Chlorambucil, European Pharmacopoeia (EP) Reference Standard, Chlorambucil, United States Pharmacopeia (USP) Reference Standard, Chlorambucil for system suitability, European Pharmacopoeia (EP) Reference Standard


ID: 1045

chemical graph of compound 1045



InChIKey: JCSGFHVFHSKIJH-UHFFFAOYSA-N
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 176158
synonyms found at PubChem are:
280744-09-4, SB 216763, 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, SB216763, SB-216763, 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-, CHEMBL102714, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione, SR-01000076052, Tocris-1616, Lopac-S-3442, D0A1YQ, AC1L41YI, Lopac0_000934, SCHEMBL30251, MLS001074894, BDBM8296, cid_176158, GTPL8015, CHEBI:91421, CTK8B4807, AOB5004, DTXSID90182349, EX-A291, SYN1075, JCSGFHVFHSKIJH-UHFFFAOYSA-N, MolPort-003-983-830, BCPP000073, HMS2235H21, HMS3244K13, HMS3244K14, HMS3244L13, HMS3262L10, HMS3268I05, HMS3373J13, HMS3654K15, KS-000008GB, ZINC1493890, Tox21_500934, ABP000231, ANW-46345, BS0214, GL9739, MFCD09753369, RS0041, s1075, AKOS015995247, ACN-029378, AN-5325, CCG-101287, CS-0139, LP00934, PB17645, NCGC00015949-01, NCGC00015949-02, NCGC00015949-03, NCGC00015949-04, NCGC00015949-05, NCGC00025232-01, NCGC00025232-02, NCGC00025232-03, NCGC00261619-01, 4CA-1130, AJ-26350, HY-12012, KB-80493, SC-73083, SMR000568414, AB0023939, AX8157915, LS-186079, RT-015653, B5716, EU-0100934, FT-0688716, ST24028269, W5100, C-8276, F10088, S 3442, SB 216763, >98% (HPLC), SB 216763/SB-216763, 744D094, A819314, J-510466, SR-01000076052-1, SR-01000076052-3, BRD-K59184148-001-04-2, 3-(2,4-DICHLOROPHENYL)-4-(1-METHYL-1H-INDOL-3-YL)-, 3-(2,4-dichlorophenyl)-4-(1-methyl-3-indolyl)pyrrole-2,5-dione, SB216763, SB-216763, 280744-09-4, 3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)-1H-pyrrole-2,5-dione, 3-(2,4-Dichlorophenyl)-4-(1-methyl- 1H-indol-3-yl)-1H-pyrrole-2,5-dione


ID: 1046

chemical graph of compound 1046



InChIKey: JCXKHYLLVKZPKE-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=NN2N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 1367
synonyms found at PubChem are:
1-aminobenzotriazole, 1614-12-6, 1H-Benzotriazol-1-amine, 1H-benzo[d][1,2,3]triazol-1-amine, benzotriazol-1-amine, 1-Benzotriazolamine, 1-Abtz, 1H-1,2,3-Benzotriazol-1-amine, 1H-1,2,3-Benzotriazol-1-ylamine, UNII-9EFF75BJ1O, NSC 114498, 9EFF75BJ1O, CHEMBL101168, benzotriazolylamine, MFCD00132902, NSC656987, AK-830/25033013, Q-102063, 1-benzotriazolylamine, benzotriazol-1-ylamine, PubChem19954, ACMC-1BVFA, rarechem aq nn 0550, AC1L1BBK, timtec-bb sbb004208, Lopac-A-3940, ABT; 1-Benzotriazolamine, D07ANY, 1h-benzotriazole,1-amino-, AC1Q4XI6, Lopac0_000056, SCHEMBL94751, MLS001056764, 1,2,3-benzotriazol-1-amine, ASIS-0066, CTK0H6517, BIA0115, DTXSID80167140, JCXKHYLLVKZPKE-UHFFFAOYSA-N, MolPort-001-768-990, ZX-AFC001579, HMS2235A14, HMS3260K13, HMS3374C01, ZINC230381, ZX-AT009876, Tox21_500056, ANW-21933, BDBM50106744, CA-921, FCH931136, NSC114498, OR5609, SBB004208, AKOS001013369, CCG-204151, INB0000279, LP00056, MCULE-8247729764, MS-1148, NSC-114498, NSC-656987, KS-00000M40, 1-Aminobenzotriazole, >=98.0% (GC), NCGC00015056-01, NCGC00015056-02, NCGC00015056-03, NCGC00015056-04, NCGC00093570-01, NCGC00093570-02, NCGC00260741-01, AK113523, AN-49537, KB-11123, LS-41531, NCI60_019729, SMR000326746, AX8056438, HY-103389, RT-001211, 4CH-024521, B7737, CS-0027797, EU-0100056, FT-0691063, ST24038267, ST51037135, A 3940, M-3405, M01240, 614A126, SR-01000075675, I10-0830, SR-01000075675-1, BRD-K19037540-001-07-8, InChI=1/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H


ID: 1047

chemical graph of compound 1047



InChIKey: JDJZONYSWOVTTL-UHFFFAOYSA-N
SMILES: C1=COC(=C1)C2=NOC(=C2)CCO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 10631189
synonyms found at PubChem are:
3-(2-Furanyl)-5-isoxazoleethanol


ID: 1048

chemical graph of compound 1048



InChIKey: JDPQWWYZTFVRDQ-UHFFFAOYSA-N
SMILES: C(C1=CC=C([NH0+]([OH0-])=O)S1)1C(C(=O)OCC=C)=C(C)NC(C)=C1C(=O)OCC=C

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Giampieri" "P Fossa" "LJ Galietta" "M Mazzei" "M Zacchigna" "F Cateni" "N Pedemonte" "MT Mazzei"


CID is 46227462
synonyms found at PubChem are:
CHEMBL604686


ID: 1049

chemical graph of compound 1049



InChIKey: JDTZAGLGBRRCJT-UHFFFAOYSA-N
SMILES: CC#CCOC(=O)C1=C(N=C2C(=C1N)C3=C(S2)CC(CC3)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 197690
synonyms found at PubChem are:
SB 205384, SB-205384, 160296-13-9, 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo(b)thieno(2,3-b)pyridine-3-carboxylic acid but-2-ynyl ester, 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester, SR-01000076138, AC1L53UD, SB 205384, solid, Lopac0_001119, MLS002153326, CHEMBL1256667, SCHEMBL17236317, CHEBI:91586, JDTZAGLGBRRCJT-UHFFFAOYSA-N, MolPort-003-959-599, HMS2232M03, HMS3263O20, HMS3268A07, HMS3370F18, Tox21_501119, BN0457, AKOS024456640, API0007584, CCG-205195, LP01119, NCGC00015969-03, NCGC00015969-04, NCGC00015969-05, NCGC00025197-02, NCGC00162349-01, NCGC00261804-01, SMR001230739, EU-0101119, S 7936, J-009707, SR-01000076138-2, SR-01000076138-3, BRD-A22707317-001-02-5, 4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-[1H]benzothieno[2,3-b]pyridine-3-carboxylic acid 2-butynyl ester, but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylate


ID: 1050

chemical graph of compound 1050



InChIKey: JDUMTSOFUMWLJQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NC2=C(OC3=CC=CC=C32)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"GL Lukacs" "LJ Galietta" "A Taddei" "AS Verkman" "H Yang" "K Du" "AA Shelat" "C Folli" "VS Gopinath" "T Ma" "N Pedemonte" "RK Guy"


CID is 570268
synonyms found at PubChem are:
3-benzamidobenzofuran-2-carboxamide, 3-benzamido-1-benzofuran-2-carboxamide, 68217-75-4, JDUMTSOFUMWLJQ-UHFFFAOYSA-N, 3-Benzoylamino-benzofuran-2-carboxylic acid amide, AC1LC69T, Cambridge id 6432655, Oprea1_760585, MLS000528875, SCHEMBL3118545, CHEMBL1308755, CTK7F8402, ZINC58361, CHEBI:115706, MolPort-001-964-434, HMS1692O04, HMS2313B21, STK070406, AKOS000507241, MCULE-7381463762, BAS 01508074, SMR000121350, ST079168, Benzofuran-2-carboxamide, 3-benzoylamino-, 2-benzofurancarboxamide, 3-(benzoylamino)-, 3-(Benzoylamino)-1-benzofuran-2-carboxamide, EU-0017189, 3-(Benzoylamino)-1-benzofuran-2-carboxamide #, 3-(phenylcarbonylamino)benzo[b]furan-2-carboxamide, 3-[(phenylcarbonyl)amino]-1-benzofuran-2-carboxamide, F0834-0768, Z108545860, A0111/0004866


ID: 1051

chemical graph of compound 1051



InChIKey: JDVVGAQPNNXQDW-TVNFTVLESA-N
SMILES: C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 54445
synonyms found at PubChem are:
castanospermine, 79831-76-8, Castinospermine, 1,6,7,8-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, 6-Epicastanospermine, UNII-Q0I3184XM7, 6,7-Diepicastanospermine, NSC 625381, CHEBI:27860, Q0I3184XM7, Castanospermine, Castanospermum australe, (1S,6S,7R,8aR)-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol, (1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol, (1S-(1alpha,6beta,7alpha,8beta,8alphabeta))-octahydro-1,6,7,8-indolizinetetrol, CTS, SR-01000597675, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol, Indolizine der., NSC625381, 2cbu, Octahydro-indolizine-1,6,7,8-tetraol, CID54445, 1-epicastanospermine, CAST, (+)-Castanospermine, D09NYB, MolMap_000013, UPCMLD-DP122, SCHEMBL61040, BSPBio_001552, KBioGR_000272, KBioSS_000272, MLS000028641, AC1L1H19, AC1Q59T8, CHEMBL311226, UPCMLD-DP122:001, UPCMLD-DP122:002, UPCMLD-DP122:003, BCBcMAP01_000133, BDBM36388, CTK8F8488, KBio2_000272, KBio2_002840, KBio2_005408, KBio3_000543, KBio3_000544, BIC0126, JDVVGAQPNNXQDW-TVNFTVLESA-N, MolPort-003-845-673, ZX-AFC000445, Bio1_000396, Bio1_000885, Bio1_001374, Bio2_000272, Bio2_000752, HMS1361N14, HMS1791N14, HMS1989N14, HMS2232G11, HMS3266B08, HMS3402N14, HY-N2022, ZINC3775177, MDL-26190, MFCD00017555, AKOS024458634, CCG-208170, CS-5633, DB01816, FCH3937985, IDI1_034022, SMP1_000059, NCGC00024773-02, NCGC00024773-04, LS-83622, SC-66601, SMR000059227, B6439, Octahydro-indolizine-1,6,7,8-tetraol, 13, C02256, SR-01000597675-1, SR-01000597675-4, W-203822, (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetraol, 81041B9A-D148-44DC-A86D-C78D6ABF9633, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, 98%, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine, [1S-(1?,6?,7?,8?,8a?)]-Octahydro-1,6,7,8-indolizinetetrol, Castanospermine, >=94% (GC), BioUltra, from Castanospermum australe seeds, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1-alpha,6-beta,7-alpha,8-beta,8a-beta))-, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1alpha,6beta,7alpha,8beta,8abeta))-, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1alpha,6beta,7alpha,8beta,8alphabeta))-


ID: 1052

chemical graph of compound 1052



InChIKey: JDZOTSLZMQDFLG-BTJKTKAUSA-N
SMILES: C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5284439
synonyms found at PubChem are:
Perhexiline maleate, 6724-53-4, Perhexiline maleate salt, Pexid, 2-(2,2-Dicyclohexylethyl)piperidine maleate, Perhexiline maleate [USAN], CCRIS 5491, C19H35N.C4H4O4, rac Perhexiline Maleate, EINECS 229-775-5, MLS000028601, MLS001077289, 2-(2,2-Dicyclohexylethyl)piperidine acid maleate, 2-(2,2-Dicyclohexylethyl)piperidine maleate (1:1), 2-(2,2-Dicyclohexylethyl)piperidinium hydrogen maleate, Piperidine, 2-(2,2-dicyclohexylethyl)-, maleate (1:1), NCGC00095025-01, SMR000058713, DSSTox_CID_1114, Piperidine, 2-(2,2-dicyclohexylethyl)-, (Z)-2-butenedioate (1:1), Perhexiline maleate (USAN), DSSTox_RID_75947, DSSTox_GSID_21114, 2-(2,2-dicyclohexylethyl)piperidine (2Z)-but-2-enedioate, SMR000653478, SR-01000000246, 2-(2,2-DICYCLOHEXYLETHYL)PIPERIDINE 2-BUTENEDIOATE, Pexsid, Pexsig, 2-[2,2-DICYCLOHEXYLETHYL]PIPERIDINE MALEATE SALT, Prestwick_636, Opera_ID_1791, PERHEXILLINE MALEATE, CAS-6724-53-4, AC1NR4G7, MLS006010628, SCHEMBL123149, SPECTRUM1503227, CHEMBL1334033, DTXSID1021114, HMS501L04, HY-B1334A, AOB5092, MolPort-003-666-460, REGID_for_CID_5284439, HMS1568J14, HMS1922K11, HMS2092P06, HMS2095J14, HMS2231C20, HMS2231N03, HMS3712J14, Pharmakon1600-01503227, Tox21_111395, CCG-39317, MFCD00057329, NSC758409, AKOS024285312, Tox21_111395_1, CS-7871, NSC-758409, NCGC00018261-06, NCGC00095025-02, NCGC00095025-03, NCGC00095025-04, ST083072, Perhexiline maleate salt, >=98% (HPLC), LS-114986, X4611, VU0239842-5, D05442, (+/-)-2-(2,2-Dicyclohexylethyl)piperidine Maleate, SR-01000000246-2, SR-01000000246-4, (Z)-but-2-enedioic acid; 2-(2,2-dicyclohexylethyl)piperidine, 2-(2,2-dicyclohexylethyl)piperidine, (2Z)but-2-enedioic acid, Piperidine, 2-(2,2-dicyclohexylethyl)-, 2-butenedioate (1:1)


ID: 1053

chemical graph of compound 1053



InChIKey: JEJFTTRHGBKKEI-UHFFFAOYSA-N
SMILES: CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 43595
synonyms found at PubChem are:
Deoxyschisandrin, Deoxyschizandrin, schisandrin A, 61281-38-7, CHEBI:80818, hexamethoxy(dimethyl)[?], R(+) Deoxyschisandrin A, Schizandrin-A, Dimethylgomisin J, AC1L2A7F, CHEMBL479898, SCHEMBL2703836, Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamethoxy-, HMS3327E22, Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer, AKOS015897176, CCG-208606, NCGC00163662-01, AN-39355, LS-60866, FT-0624519, Deoxyschizandrin, 98%, from magnoliavine P.E, C16951, W-2898, I07-0289, 5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene


ID: 1054

chemical graph of compound 1054



InChIKey: JEKMKNDURXDJAD-HWUKTEKMSA-N
SMILES: C[C@@]12C=CC3=C([C@H]1CC[C@]45[C@H]2CC[C@H](C4)[C@](C5)(CO)O)C=CO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 114778
synonyms found at PubChem are:
Kahweol, 6894-43-5, CCRIS 1521, 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS,5aS,7R,8R,10aR,10bS)-, 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-, AC1L3FY2, SCHEMBL237066, CHEMBL1494598, SCHEMBL18058616, ZINC6032238, NCGC00163593-01, LS-185961, SR-05000002309, SR-05000002309-2, 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-


ID: 1055

chemical graph of compound 1055



InChIKey: JEMJAABFSYOLAP-UHFFFAOYSA-N
SMILES: CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5368
synonyms found at PubChem are:
t-0156, T0156, CHEMBL540294, methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate, NCGC00016057-01, Tocris-1676, Lopac-T-8067, D0LZ5R, Lopac0_001212, SCHEMBL687326, AC1L1K75, GTPL5275, CHEMBL1190161, CHEBI:93111, CTK6I8577, ZINC3963610, BDBM50130017, HSCI1_000141, CCG-205286, NCGC00016057-02, NCGC00016057-03, NCGC00025257-01, NCGC00025257-02, BRD-K63516691-001-01-6, BRD-K63516691-003-01-2, 1-Oxo-2-(2-methyl-4-pyridinylmethyl)-4-(3,4,5-trimethoxyphenyl)-8-(2-pyrimidinylmethoxy)-1,2-dihydro-2,7-naphthyridine-3-carboxylic acid methyl ester, 2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-[2,7]naphthyridine-3-carboxylic acid methyl ester; hydrochloride, methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate


ID: 1056

chemical graph of compound 1056



InChIKey: JETSDIPTVSZMLI-UHFFFAOYSA-N
SMILES: CC1=CC(=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4119
synonyms found at PubChem are:
methoxyvone, Spectrum_000014, AC1L1HGD, Spectrum2_000056, Spectrum3_001778, Spectrum4_000130, Spectrum5_000894, BSPBio_003275, KBioGR_000520, KBioSS_000354, DivK1c_000643, SPECTRUM1400666, SPBio_000211, SCHEMBL3409370, CHEMBL1591080, CTK6J5442, HMS502A05, KBio1_000643, KBio2_000354, KBio2_002922, KBio2_005490, KBio3_002776, CHEBI:114181, JETSDIPTVSZMLI-UHFFFAOYSA-N, NINDS_000643, CCG-39990, 7-methoxy-5-methyl-2-phenyl-chromone, IDI1_000643, NCGC00095871-01, NCGC00095871-02, NCGC00178171-01, 7-methoxy-5-methyl-2-phenylchromen-4-one, 7-methoxy-5-methyl-2-phenyl-4h-chromen-4-one, BRD-K56057104-001-02-9, BRD-K56057104-001-03-7


ID: 1057

chemical graph of compound 1057



InChIKey: JFACETXYABVHFD-WXPPGMDDSA-N
SMILES: CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)OC)C)C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 159516
synonyms found at PubChem are:
Pristimerin, 1258-84-0, Celastrol-methylether, UNII-28ZK7PR57S, GNF-PF-476, 28ZK7PR57S, CHEBI:8416, 24-Nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, Pristimerine, methyl (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate, (9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26 -trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester, C30H40O4, methyl (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylate, Celastrol methyl ester, Spectrum_001558, SpecPlus_000649, Spectrum2_000546, Spectrum3_001651, Spectrum4_001681, Spectrum5_000322, AC1L4LZ3, SCHEMBL15020, BSPBio_003401, KBioGR_001942, KBioSS_002038, CHEMBL54804, DivK1c_006745, SPECTRUM1504181, SPBio_000591, MEGxp0_000269, DTXSID5044027, ACon0_000836, CTK4B4863, KBio1_001689, KBio2_002038, KBio2_004606, KBio2_007174, KBio3_002621, MolPort-001-740-445, BCP22624, HY-N1937, ZINC4097723, CCG-38723, MFCD01711331, AKOS032960306, API0006380, CS-6257, SDCCGMLS-0066814.P001, NCGC00178090-01, AN-48942, LS-97293, B7488, ST24049037, X1210, C08633, Q-100112, 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oicacid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, (9b,13a,14b,20a)-, D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20alpha)-, D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20alpha)- (9CI)


ID: 1058

chemical graph of compound 1058



InChIKey: JFBIRMIEJBPDTQ-UHFFFAOYSA-N
SMILES: C1=CC=NC(=C1)C2=NN=C(N=N2)C3=CC=CC=N3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 315109
synonyms found at PubChem are:
1671-87-0, 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine, 3,6-Di(2-pyridyl)-1,2,4,5-tetrazine, 3,6-Di-2-pyridinyl-1,2,4,5-tetrazine, 3,6-Bis(2-pyridyl)-1,2,4,5-tetrazine, 3,6-Di-2-pyridyl-1,2,4,5-tetrazine, 3,6-dipyridin-2-yl-1,2,4,5-tetrazine, MLS000038825, SMR000034589, 3,6-Bis(2-pyridinyl)-1,2,4,5-tetrazine, 1,2,4,5-Tetrazine, 3,6-di-2-pyridinyl-, Bptz, NSC238155, ACMC-209dvt, AC1L7QZV, cid_315109, SCHEMBL2852298, 3,6-Di-2-pyridyl-s-tetrazine, CHEMBL1519146, BDBM41205, CTK4D2571, DTXSID30311116, 3,6-Di(2-pyridyl)-s-tetrazine, MolPort-002-546-239, HMS2750C04, ZINC198788, KS-00000NF7, ANW-22263, CL8001, STK792988, AKOS005611188, MCULE-6801268759, NSC-238155, bis(pyridin-2-yl)-1,2,4,5-tetrazine, AJ-17847, AK-86506, AN-49659, AS-18149, KB-70251, ZB009483, DB-026020, ST2404655, TC-111008, 1,2,4,5-Tetrazine,3,6-di-2-pyridinyl-, 3,6-di(2-pyridinyl)-1,2,4,5-tetraazine, CS-0037379, D3640, FT-0614750, W3633, 3,6-Di-2-pyridyl-1,2,4,5-tetrazine, 96%, 671D870, AE-848/01001002, C-57343, J-010344, I14-49632


ID: 1059

chemical graph of compound 1059



InChIKey: JFIOVJDNOJYLKP-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1Cl)O)SC2=CC(=CC(=C2O)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2406
synonyms found at PubChem are:
bithionol, 97-18-7, Actamer, Bithin, 2,2'-Thiobis(4,6-dichlorophenol), Lorothidol, Bitionol, Bithionol sulfide, Bidiphen, Bisoxyphen, Lorothiodol, Bitin, Bithionolate, Neopellis, Nobacter, Vancide BL, Usaf B-22, Bithional, Bithionolum, 2-Hydroxy-3,5-dichlorophenyl sulfide, TKhsd, Bis(2-hydroxy-3,5-dichlorophenyl) sulfide, Bis(3,5-dichloro-2-hydroxyphenyl) sulfide, Caswell No. 852, 2,2'-sulfanediylbis(4,6-dichlorophenol), Bitionol [INN-Spanish], XL 7, Bithionolum [INN-Latin], 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenyl sulfide, Prevenol, 2-Hydroxy-3,5-dichlorophenyl sulphide, CP 3438, D 26, NCI-C60628, UNII-AMT77LS62O, C12H6Cl4O2S, NSC 47129, Phenol, 2,2'-thiobis[4,6-dichloro-, CCRIS 2043, HSDB 6380, EINECS 202-565-0, EPA Pesticide Chemical Code 064201, Phenol, 2,2'-thiobis(4,6-dichloro-, BRN 2003535, AMT77LS62O, 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylsulfide, AI3-50518, MLS000028403, CHEBI:3131, XL-7, 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol, 2,2'-Thiobis[4,6-dichlorophenol], 2,2'-Thio-bis(4,6-dichlorophenol), NCGC00018163-06, SMR000058374, 2,4-dichloro-6-(3,5-dichloro-2-hydroxy-phenyl)sulfanyl-phenol, DSSTox_CID_1342, DSSTox_RID_76096, DSSTox_GSID_21342, Q-200730, Phenol,2'-thiobis[4,6-dichloro-, WLN: QR BG DG FSR BQ CG EG, 2,3',5,5'-tetrachlorodiphenyl sulfide, CAS-97-18-7, 6-(3,5-dichloro-2-hydroxyphenylthio)-2,4-dichlorophenol, Bithionol [INN:BAN:JAN], Bithionol [INN:BAN:JAN:NF], B1T, Bithin (TN), Spectrum_000088, Bithionol (JAN/INN), AC1L1DLT, Spectrum2_000113, Spectrum3_000319, Spectrum4_000257, Spectrum5_000922, D0QQ1J, cid_2406, PHENOL, 2,2'-THIOBIS(4,6-DICHLORO)-, Oprea1_473080, REGID_for_CID_2406, SCHEMBL64385, BSPBio_001918, KBioGR_000694, KBioSS_000508, ARONIS27111, DivK1c_000639, SPBio_000126, ACMC-209s88, CHEMBL290106, GTPL2338, Bithionol, >=98% (HPLC), DTXSID9021342, BDBM36880, CTK8B2783, HMS501P21, JFIOVJDNOJYLKP-UHFFFAOYSA-, KBio1_000639, KBio2_000508, KBio2_003076, KBio2_005644, KBio3_001418, NSC9872, JFIOVJDNOJYLKP-UHFFFAOYSA-N, MolPort-003-702-306, NINDS_000639, KUC106451N, ZINC608213, 2,2-thiobis(4,6-dichlorophenol), KS-000048LK, NSC-9872, NSC47129, Tox21_110832, Tox21_200384, Tox21_302919, 6068AF, A1B988, ANW-40854, MFCD00055727, NSC-47129, s4552, SBB071906, STL257451, 2,2'-Thiobis (4,6-dichlorophenol), 2,2'-Thiobis-(4,6-dichlorophenol), AKOS015856712, Tox21_110832_1, CS-3874, DB04813, KSC-19-055, LS-2022, MCULE-6591279983, RTR-030210, IDI1_000639, QTL1_000014, NCGC00018163-01, NCGC00018163-02, NCGC00018163-03, NCGC00018163-04, NCGC00018163-05, NCGC00018163-07, NCGC00018163-08, NCGC00018163-09, NCGC00018163-10, NCGC00021272-04, NCGC00021272-05, NCGC00021272-06, NCGC00256573-01, NCGC00257938-01, AN-42826, HY-17592, KB-75549, SC-46723, ZB014602, SBI-0051298.P003, TL8006856, TR-030210, FT-0707601, ST45027186, bis (2-hydroxy-3,5-dichlorophenyl)-sulphide, Bithionol, VETRANAL(TM), analytical standard, C07967, D00802, BIS(2-HYDROXY-3,5-DICHLOROPHENYL)SULFIDE, I09-1509, BRD-K39120595-304-03-9, 2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol, 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)thio]phenol, 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)thio]phenol, 2-[3,5-bis(chloranyl)-2-oxidanyl-phenyl]sulfanyl-4,6-bis(chloranyl)phenol, 1394-04-3, InChI=1/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H


ID: 1060

chemical graph of compound 1060



InChIKey: JFRJCQJVFMHZOO-QZHHGCDDSA-N
SMILES: C1=CC(=CC=C1CC(=O)NC2=CC=C(C=C2)CC(=O)NCCN)NC3=NC=NC4=C3N=CN4[C@H]5[C@@H]([C@@H]([C@H](O5)CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 126054
synonyms found at PubChem are:
CHEMBL1512545, 96760-69-9, Adenosine amine congener hydrate, N-(4-(2-((4-(2-((2-Aminoethyl)amino)-2-oxoethyl)phenyl)amino)-2-oxoethyl)phenyl)adenosine, n-(4-{2-[(4-{2-[(2-aminoethyl)amino]-2-oxoethyl}phenyl)amino]-2-oxoethyl}phenyl)adenosine, 6-Adac, AC1L2POH, AC1Q5PIM, MLS002153192, SCHEMBL3486807, Adenosine amine congener hydrate, MolPort-019-997-103, HMS2231C21, ZINC4475057, BDBM50396917, AKOS030573826, NCGC00163296-01, SMR001230680, A825579, Adenosine, N-(4-(2-((4-(2-((2-aminoethyl)amino)-2-oxoethyl)phenyl)amino)-2-oxoethyl)phenyl)-, N-(2-aminoethyl)-2-[4-[[2-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-6-purinyl]amino]phenyl]-1-oxoethyl]amino]phenyl]acetamide, N-(2-aminoethyl)-2-[4-[[2-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]acetyl]amino]phenyl]acetamide, N-(2-azanylethyl)-2-[4-[2-[4-[[9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]phenyl]ethanoylamino]phenyl]ethanamide, N-[4-[[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]phenyl]amino]carbonyl]methyl]phenyl]adenosine, N6-[4-[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]-anilino]carbonyl]methyl]phenyl]adenosine


ID: 1061

chemical graph of compound 1061



InChIKey: JFSHUTJDVKUMTJ-QHPUVITPSA-N
SMILES: C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 73145
synonyms found at PubChem are:
beta-Amyrin, 559-70-6, Amyrin, beta-Amyrenol, Olean-12-en-3beta-ol, UNII-KM8353IPSO, 3beta-hydroxyolean-12-ene, KM8353IPSO, CHEMBL455098, CHEBI:10352, (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol, b-amyrenol, beta.-Amyrenol, beta.-Amyrin, B-Amyrin, B-Amyrin with hplc, EINECS 209-204-6, NSC 527971, AC1L2JCQ, Olean-12-en-3|A-ol, SCHEMBL377754, (3beta)-olean-12-en-3-ol, AC1Q296T, beta-Amyrin, analytical standard, JFSHUTJDVKUMTJ-QHPUVITPSA-N, MolPort-003-925-568, ZX-AFC002758, (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol, ZINC3978270, (3-.beta.)-Olean-12-en-3-ol, BDBM50241955, AKOS032962060, LMPR0106150015, AN-45932, CC-24585, SC-74203, Olean-12-en-3-ol, (3beta)- (9CI), V0161, C08616, 559A706, C-22188, (3S,4aR,5R,6aR,6bR,8S,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol


ID: 1062

chemical graph of compound 1062



InChIKey: JGABMVVOXLQCKZ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3N2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 161091
synonyms found at PubChem are:
2-phenylquinolin-4-ol, 1144-20-3, 2-Phenyl-1H-quinolin-4-one, 2-Phenyl-4-quinolone, 14802-18-7, 2-Phenyl-4-oxohydroquinoline, 4-Hydroxy-2-phenylquinoline, 2-Phenyl-4(1H)-quinolinone, 4(1H)-Quinolinone, 2-phenyl-, 2-Phenyl-4-quinolinol, MLS000084697, MLS000737592, CHEMBL277148, GNF-PF-4337, JGABMVVOXLQCKZ-UHFFFAOYSA-N, SMR000019044, AB-321/11436913, YT-1 Compound, 1-Azaflavone, 2-phenylquinolin-4(1h)-one, NSC28866, 2-phenyl-quinolin-4-ol, Maybridge1_004160, 2-Phenyl-4-oxy-chinoline, 4-Quinolinol, 2-phenyl-, AC1L4OS4, AC1Q6B8D, 2-Phenyl-4-hydroxyquinoline, Oprea1_460285, SCHEMBL367268, cid_161091, BDBM48563, CTK0H4730, CTK8H0086, HMS553F04, JGABMVVOXLQCKZ-UHFFFAOYSA-, 2-Phenyl-4(1H)-quinolinone #, DTXSID80163869, MolPort-002-486-526, MolPort-002-903-890, HMS2357D14, KUC100225N, ZINC8578607, ANW-73205, CCG-15202, NSC-28866, AKOS000283836, AKOS009868209, MCULE-7831289255, ABA-1056487, NCGC00159760-01, AC-20865, AJ-57641, AN-48716, DB-009183, KB-174134, TC-060573, FT-0723846, FT-0750129, T6170, AB00404244-09, 144P203, A803182, SR-01000391113, SR-01000391113-1, I14-43421, 7L4, InChI=1/C15H11NO/c17-15-10-14(11-6-2-1-3-7-11)16-13-9-5-4-8-12(13)15/h1-10H,(H,16,17)


ID: 1063

chemical graph of compound 1063



InChIKey: JGFYQVQAXANWJU-UHFFFAOYSA-M
SMILES: C(C(=O)[O-])F.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6123
synonyms found at PubChem are:
sodium fluoroacetate, Sodium monofluoroacetate, 62-74-8, Furatol, Yasoknock, Compound 1080, Fratol, Tenate, Fluoroacetic acid sodium salt, Natriumfluoracetat, Fluorakil 3, Sodium fluoacetate, Sodium fluoracetate, Caswell No. 770, Ratbane 1080, Sodium fluoacetic acid, Fluoroctan sodny [Czech], Latka 1080 [Czech], RCRA waste number P058, Natriumfluoracetaat [Dutch], Natriumfluoracetat [German], Sodium fluoroacetate [ISO], Fluoroacetic acid, sodium salt, HSDB 743, UNII-166WTM3843, Sodium fluoroacetate de [French], Sodio, fluoracetato di [Italian], Natriumfluoracetaat, Acetic acid, fluoro-, sodium salt, EINECS 200-548-2, Fluoroacetic acid sodium salt [BSI], Monofluoressigsaures natrium [German], NSC 77690, UN2629, Fluoroacetate de sodium [ISO-French], RCRA waste no. P058, EPA Pesticide Chemical Code 075003, Sodio, fluoracetato di, Sodium fluoroacetate de, AI3-08434, CHEBI:38699, Monofluoressigsaures natrium, 166WTM3843, sodium;2-fluoroacetate, Acetic acid, 2-fluoro-, sodium salt (1:1), Fluoroctan sodny, 144-49-0 (Parent), sodium fluoroacetate,fluoro acetic acid sodium salt,gifblaar poison, compd 1080, Fluoroacetate de sodium, Latka 1080, Sodium Fluoro-Acetate, sodium 2-fluoroacetate, Fluoroacetic acid sodium, Spectrum2_000664, Spectrum3_001693, Spectrum4_000925, Spectrum5_001848, DSSTox_CID_4311, DSSTox_RID_77363, DSSTox_GSID_24311, KBioGR_001450, SPECTRUM330009, SCHEMBL226060, SPBio_000727, CHEMBL369611, DTXSID8024311, CTK5B5863, KBio3_002466, JGFYQVQAXANWJU-UHFFFAOYSA-M, MolPort-001-776-560, Tox21_301420, CCG-40063, AKOS025295568, CAS-62-74-8, NCGC00095771-01, NCGC00255312-01, LS-12190, Sodium fluoroacetate [UN2629] [Poison], Sodium fluoroacetate [UN2629] [Poison], TR-021583, Acetic acid, 2-fluoro-,sodium salt (1:1), F0031, FT-0626471, C18588, Fluoroacetic acid sodium salt 10 ng/microL in Water


ID: 1064

chemical graph of compound 1064



InChIKey: JGMOKGBVKVMRFX-HQZYFCCVSA-N
SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@@H]3[C@H]2C=CC4=CC(=O)CC[C@@]34C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 9051
synonyms found at PubChem are:
dydrogesterone, Isopregnenone, 152-62-5, Hydrogesterone, Duphaston, Hydrogestrone, Gestatron, Diphaston, Dufaston, Gynorest, 10alpha-Isopregnenone, Duvaron, Prodel, Retrone, Terolut, Dydrogesteronum, Didrogesterone [DCIT], Didrogesterone, Dydrogesterona, Retro-6-dehydroprogesterone, Dydrogesteronum [INN-Latin], Dydrogesterona [INN-Spanish], delta(6)-Retroprogesterone, Dehydrogesterone, 6-Dehydro-retro-progesterone, delta(sup 6)-Retroprogesterone, 9beta,10alpha-Pregna-4,6-diene-3,20-dione, didrogesterona, Retroprogesterone, 6-dehydro-, Duphaston (TN), UNII-90I02KLE8K, 6-Dehydro-9beta,10alpha-progesterone, Gynorest (TN), CCRIS 9069, HSDB 3321, 6-Dehydroretroprogesterone, EINECS 205-806-8, 9-beta,10alpha-Pregna-4,6-diene-3,20-dione, NSC 92336, Dydrogesterone [USAN:INN:BAN:JAN], (9-beta,10-alpha)-Pregna-4,6-diene-3,20-dione, Pregna-4,6-diene-3,20-dione, (9beta,10alpha)-, 6-Dehydro-9 beta-10 alpha-progesterone, MLS002153947, 90I02KLE8K, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one, CHEBI:31527, (9beta,10alpha)-pregna-4,6-diene-3,20-dione, 9-beta,10-alpha-Pregna-4,6-diene-3,20-dione, 6-Dehydro-9.beta.,10.alpha.-progesterone, DSSTox_CID_2974, DSSTox_RID_76812, DSSTox_GSID_22974, 9beta,10alpha-Pregna-4,6-diene-3,20-dione (8CI), CAS-152-62-5, MLS002695106, NSC92336, NCGC00016413-01, 6 Dehydro 9 beta 10 alpha progesterone, Dydrogesterone [USAN:USP:INN:BAN:JAN], DELTA6-Retroprogesterone, Prestwick0_000671, Prestwick1_000671, Prestwick2_000671, Prestwick3_000671, D0F1UL, AC1L1S7M, .DELTA.6-Retroprogesterone, SCHEMBL37703, BSPBio_000761, Solvay Brand of Dydrogesterone, SPBio_002682, BPBio1_000839, GTPL2878, CHEMBL1200853, DTXSID1022974, HY-B0257A, 9.beta.,6-diene-3,20-dione, Dydrogesterone (JP15/USP/INN), Dydrogesterone (JP17/USP/INN), JGMOKGBVKVMRFX-HQZYFCCVSA-N, HMS1570G03, HMS2097G03, HMS2230C10, HMS3714G03, 9-.beta.,6-diene-3,20-dione, BCP12878, ZINC3875998, Tox21_110429, NSC-92336, AKOS015895532, Tox21_110429_1, AN-5183, CCG-220671, CS-2434, DB00378, GS-6735, NCGC00179445-01, NCGC00179445-03, NCGC00179445-04, BC219535, CC-27423, I033, SC-71085, SMR001233286, LS-118418, AB00513884, (9?,10?)-Pregna-4,6-diene-3,20-dione, D01217, Pregna-4,20-dione, (9.beta.,10.alpha.)-, Pregna-4,6-diene-3,20-dione, (9b,10a)-, AB00513884_04, 152D625, C-23776, SR-01000841256, 9.beta.,10.alpha.-Pregna-4,6-diene-3,20-dione, I06-1088, SR-01000841256-2, W-108050, 9-.beta.,10.alpha.-Pregna-4,6-diene-3,20-dione, BRD-K68620903-001-03-1, BRD-K68620903-001-11-4, Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)-, Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)-(9CI), Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)- (9CI), (1R,2S,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-6,8-dien-5-one, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one


ID: 1065

chemical graph of compound 1065



InChIKey: JGUZGNYPMHHYRK-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC(=C(C2=O)O)C3=CC(=C(C=C3)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5281691
synonyms found at PubChem are:
Rhamnetin, 90-19-7, 7-Methoxyquercetin, beta-Rhamnocitrin, 7-O-Methylquercetin, 7-Methylquercetin, Quercetin 7-methyl ether, 3,5,3',4'-Tetrahydroxy-7-methoxyflavone, 7-O-Methyl Quercetin, C.I. 75690, 3,3',4',5-Tetrahydroxy-7-methoxyflavone, NSC 19802, .beta.-Rhamnocitrin, CCRIS 3792, UNII-71803L5F4S, NSC19802, EINECS 201-974-1, BRN 0047741, CHEMBL312163, CHEBI:74992, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one, MFCD00016931, NSC-19802, 71803L5F4S, 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, W-100338, FLAVONE, 7-METHOXY-3,3',4',5-TETRAHYDROXY-, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-chromen-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one, AC1NQYWJ, quercetin-7-methylether, Spectrum_001185, 3,5,3',4'-Tetrahydroxy-7-methoxyflaone, SpecPlus_000463, Spectrum2_000642, Spectrum3_001343, Spectrum4_001872, Spectrum5_000464, BSPBio_003125, KBioGR_002367, KBioSS_001665, SPECTRUM310031, 5-18-05-00495 (Beilstein Handbook Reference), DivK1c_006559, Rhamnetin, analytical standard, SCHEMBL555118, SPBio_000643, BDBM23410, CTK8G2947, KBio1_001503, KBio2_001665, KBio2_004233, KBio2_006801, KBio3_002345, DTXSID40237979, JGUZGNYPMHHYRK-UHFFFAOYSA-N, MolPort-003-665-818, ZINC3875620, 6323AF, CCG-38555, LMPK12112624, AKOS027320587, 3,4',5-Tetrahydroxy-7-methoxyflavone, SDCCGMLS-0066624.P001, NCGC00095624-01, NCGC00095624-02, NCGC00095624-03, NCGC00178254-01, AN-42510, LS-69024, NCI60_001648, 3 3' 4' 5-tetrahydroxy-7-methoxyflavone, Flavone,3',4',5-tetrahydroxy-7-methoxy-, LY 805921, FT-0672192, ST50331696, C10176, Flavone, 3,3',4',5-tetrahydroxy-7-methoxy-, C-57547, SR-05000002269, SR-05000002269-2, 3,5,3',4'-Tetrahydroxy-7-methoxyflavone with HPLC, BRD-K37206356-001-01-3, Flavone, 3,3',4',5-tetrahydroxy-7-methoxy- (8CI), 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-y-methoxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy- (9CI)


ID: 1066

chemical graph of compound 1066



InChIKey: JHEWMLHQNRHTQX-UHFFFAOYSA-N
SMILES: CCCCCC1=C2C(=CC(=C1C(=O)O)O)OC(=O)C3=C(O2)C=C(C=C3C(=O)CCCC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 73157
synonyms found at PubChem are:
Lobaric acid, 522-53-2, CHEMBL551842, Lobraric acid, lobutoic Acid, Usnetic acid, Stereocaulic acid, 11H-Dibenzo(b,e)(1,4)dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, Spectrum_000626, AC1Q5UMD, Spectrum2_000310, Spectrum3_001177, Spectrum4_001443, Spectrum5_000025, AC1L2JD8, BSPBio_002793, KBioGR_001925, KBioSS_001106, SPECTRUM300018, cid_73157, MLS001049101, REGID_for_CID_73157, SPBio_000280, SCHEMBL3910434, CHEBI:93548, CTK1H2657, KBio2_001106, KBio2_003674, KBio2_006242, KBio3_002293, DTXSID30200238, JHEWMLHQNRHTQX-UHFFFAOYSA-N, HMS2271L13, NP335, ZINC2139624, ACM522532, BDBM50294526, CCG-38587, AKOS015969735, SDCCGMLS-0066497.P001, NCGC00095570-01, NCGC00095570-02, 8-Hydroxy-3-methoxy-11-oxo-1-pentanoyl-6-pentyl-11H-dibenzo[b,E][1,4]dioxepine-7-carboxylic acid, SMR000386933, SR-01000758235, SR-01000758235-2, BRD-K88849294-001-02-1, BRD-K88849294-001-08-8, 3-hydroxy-9-methoxy-6-oxo-7-pentanoyl-1-pentylbenzo[b][1,4]b, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-6-pentyl-1-valeryl-, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, 3-hydroxy-9-methoxy-6-oxo-7-pentanoyl-1-pentylbenzo[b][1,4]benzodioxepine-2-carboxylic acid, 8-Hydroxy-3-methoxy-11-oxo-1-pentanoyl-6-pentyl-11H-dibenzo[b,E][1,4]dioxepine-7-carboxylic acid #


ID: 1067

chemical graph of compound 1067



InChIKey: JHPHVAVFUYTVCL-UHFFFAOYSA-M
SMILES: CC(C[N+](C)(C)C)OC(=O)C.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6114
synonyms found at PubChem are:
Methacholine chloride, 62-51-1, Acetyl-beta-methylcholine chloride, Provocholine, Mecholyl chloride, Amechol, Methacholine (chloride), Mecholine chloride, 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride, Methacholinium chloride, Acetyl-2-methylcholine Chloride, (2-Acetoxypropyl)trimethylammonium chloride, Metacolina cloruro [DCIT], O-Acetyl-beta-methylcholine chloride, beta-Methylacetylcholine chloride, Cloruro de metacolina [Spanish], Chlorure de methacholine [French], Methacholini chloridum [INN-Latin], EINECS 200-537-2, Cloruro de metacolina [INN-Spanish], DL-Acetyl-beta-methylcholine chloride, Chlorure de methacholine [INN-French], (+-)-Acetyl-beta-methylcholine chloride, AI3-51680, MLS000069656, Trimethyl-beta-acetoxypropylammonium chloride, CHEBI:50142, (2-Hydroxypropyl)trimethylammonium chloride acetate, Mecholyl, Provokit, SMR000059224, 2-acetyloxypropyl(trimethyl)azanium chloride, DSSTox_CID_3271, A-1480, DSSTox_RID_76951, DSSTox_GSID_23271, Q-200715, 2-acetyloxy-N,N,N-trimethylpropan-1-aminium chloride, (+-)-(2-Hydroxypropyl)trimethylammonium chloride acetate, Acetyl- beta-methylcholine chloride, AMMONIUM, (2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, ACETATE, 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1), 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride, (+-)-, Metacolina cloruro, Cloruro de metacolina, Methacholini chloridum, Chlorure de methacholine, SR-01000000215, 2-acetyloxypropyl(trimethyl)azanium;chloride, Acetyl-beta-methacholine Chloride, Methacholine chloride [INN:BAN], Prestwick_981, Provocholine (TN), Methacholine chloride [USP:INN:BAN], CAS-62-51-1, Opera_ID_1285, NCGC00016282-01, AC1L1LU3, 55-92-5 (parent), REGID_for_CID_6114, SCHEMBL69104, C6H11ClNO2.C2H6, MLS001148375, SPECTRUM1500391, 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride, CHEMBL1200764, DTXSID7023271, Acetyl- --methylcholine chloride, CTK8B3014, BIA1090, MolPort-003-666-228, ZX-AFC001554, HMS1570G20, HMS1920L11, HMS2091D06, HMS2097G20, HMS2232B07, HMS3260E11, HMS3371L18, HMS3714G20, Pharmakon1600-01500391, O-Acetyl-|A-methylcholine Chloride, HY-A0083, Tox21_110348, Tox21_500025, 7986AF, ANW-41597, CCG-39988, NSC757090, Acetyl b-methylcholine chloride 98%+, AKOS015892295, Tox21_110348_1, API0024317, LP00025, MCULE-3342474130, Methacholine chloride (JAN/USAN/INN), NSC-757090, NCGC00015045-09, NCGC00093548-01, NCGC00093548-02, NCGC00093548-03, NCGC00093548-04, NCGC00093548-05, NCGC00260710-01, AN-23724, LS-18501, 2-acetoxypropyl(trimethyl)ammonium chloride, TR-021497, 2-acetyloxypropyl(trimethyl)ammonium chloride, AE>> OOo pound(1/4)x>>umicro (1/4)i, EU-0100025, FT-0628268, M0073, ST51039038, A 2251, D04970, AE>> OOo pound-|A-(1/4)x>>umicro (1/4)i, A833819, C-08885, 1-methyl-2-(trimethylamino)ethyl acetate, chloride, 2-acetoxy-N,N,N-trimethylpropan-1-aminium chloride, I02-5955, SR-01000000215-2, SR-01000000215-4, SR-01000000215-7, 2-(acetyloxy)-N,N,N-trimethylpropan-1-aminium chloride, (+/-)-(2-Hydroxypropyl)trimethylammonium chloride acetate, 2410-07-3


ID: 1068

chemical graph of compound 1068



InChIKey: JHRGJMLMFWJXOG-UHFFFAOYSA-N
SMILES: C1C(=O)NN(C1=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 268117
synonyms found at PubChem are:
1-phenylpyrazolidine-3,5-dione, 19933-22-3, 1-Phenyl-3,5-pyrazolidinedione, 1-Phenyl-pyrazolidine-3,5-dione, 3,5-Pyrazolidinedione,1-phenyl-, 3,5-Pyrazolidinedione, 1-phenyl-, AC1L6JKS, AC1Q6EBL, AC1Q6M6W, 1-phenyl-3,5-pyrazolinedione, SCHEMBL3043229, NIOSH/UQ8667200, CTK4E2773, DTXSID60296189, JHRGJMLMFWJXOG-UHFFFAOYSA-N, MolPort-000-893-764, MolPort-039-343-504, NSC108218, STL388177, STL477187, ZINC17885419, 1-phenyl-1,2-diazolidine-3,5-dione, AKOS000312935, MCULE-5848870096, NSC-108218, KB-219741, LS-128716, BB 0238358, ST51010831, UQ86672000, EN300-65929, AE-641/00375061, 2,4-dihydro-2-phenyl-5-hydroxy-3H-pyrazol-3-one, 5-hydroxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one


ID: 1069

chemical graph of compound 1069



InChIKey: JHTMQDBBUHLBPF-UHFFFAOYSA-N
SMILES: C1CCC(C1)C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"GL Lukacs" "LJ Galietta" "A Taddei" "AS Verkman" "H Yang" "K Du" "AA Shelat" "C Folli" "VS Gopinath" "T Ma" "N Pedemonte" "RK Guy"


CID is 672766
synonyms found at PubChem are:
AC1LDQTT, Oprea1_845061, SCHEMBL3128067, ZINC34601, AKOS003872668, ST050179, EU-0008274, SR-01000463429, SR-01000463429-1, A2796/0118147, 2-(cyclopentanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(cyclopentylcarbonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide


ID: 1070

chemical graph of compound 1070



InChIKey: JHYXBPPMXZIHKG-UHFFFAOYSA-N
SMILES: C1C(C(=O)C2=C(O1)C=C(C=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"LC Pyle" "PA Sloane" "JC Fulton" "S Barnes" "J Prasain" "SM Rowe" "K Backer" "M Mazur" "JP Clancy"


CID is 176907
synonyms found at PubChem are:
dihydrodaidzein, 17238-05-0, 7-hydroxy-3-(4-hydroxyphenyl)chroman-4-one, Dihydrodaidzein (keto), Dihydrodazein, (+/-)-Dihydrodaidzein, Dihydro Daidzein, 7,4'-Dihydroxyisoflavanone, 4',7-Dihydroxyisoflavanone, JHYXBPPMXZIHKG-UHFFFAOYSA-N, 2,3-dihydro-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, Isoflavanone, 4',7-dihydroxy-, AC1L42FE, 4',7-dihydroxy-Isoflavanone, (R,S)-2,3-Dihydrodaidzein, SCHEMBL131543, SCHEMBL16152440, CHEBI:75842, CTK8C3008, BID0517, MolPort-003-846-731, ZX-AFC001619, HY-N1461, ANW-69504, IN2311, LMPK12050447, AKOS016006054, ACM17238050, AK-61048, KB-82949, AX8208356, LS-193361, TC-158249, 7-Hydroxy-3-(4-hydroxyphenyl)-4-chromanone, CS-0016908, D4239, FT-0666948, J-010813, 7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one


ID: 1071

chemical graph of compound 1071



InChIKey: JIBZSGQTCBWUKL-RGMNGODLSA-N
SMILES: CC(=NCCC[C@@H](C(=O)O)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 177903
synonyms found at PubChem are:
150403-88-6, L-N5-(1-Iminoethyl)ornithine hydrochloride, N5-(1-Iminoethyl) L-Ornithine Hydrochloride, N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO), L-Ornithine, N5-(1-iminoethyl)-, monohydrochloride, (S)-5-Acetimidamido-2-aminopentanoic acid hydrochloride, L-NIO hydrochloride, 36889-13-1, EU-0100683, AC1L431A, SCHEMBL1320518, CHEMBL1256394, CTK8E7008, DTXSID40164539, AKOS025294561, L-Ornithine |x-acetamidine hydrochloride, N|A-(Iminoethyl)-L-ornithine Hydrochloride, RT-014044, FT-0670311, L-N5-(1-Iminoethyl) ornithine,hydrochloride, I 8768, N(5)-(1-Iminoethyl)-L-ornithine hydrochloride, SR-01000075505, J-008698, SR-01000075505-1, L-N5-(1-Iminoethyl)ornithine hydrochloride, >=95% (HPLC), (2S)-2-amino-5-(1-aminoethylideneamino)pentanoic acid hydrochloride


ID: 1072

chemical graph of compound 1072



InChIKey: JIVPVXMEBJLZRO-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2732
synonyms found at PubChem are:
chlorthalidone, Chlortalidone, 77-36-1, Phthalamudine, Chlorphthalidolone, Hygroton, Chlorthalidon, Phthalamodine, Chlorothalidone, Chlorphthalidone, Natriuran, Saluretin, Thalitone, Zambesil, Igroton, Isoren, Oradil, Renon, Hydro-Long, Oxodolin, Chlortalidonum, Clortalidone, Higroton, Famolin, Urolin, Oksodolin (oxodolin), Racemic chlorthalidone, Clortalidona, Oxodoline, (+-)-Hygroton, Clortalidone [DCIT], (+-)-Chlorthalidone, 2-Chloro-5-(1-hydroxy-3-oxoisoindolin-1-yl)benzenesulfonamide, Chlortalidonum [INN-Latin], Clortalidona [INN-Spanish], G-33182, Tenoretic, G 33182, 1-Keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline, 2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide, 3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine, Thalitone (TN), C14H11ClN2O4S, Hygroton (TN), 3-(4'-Chloro-3'-sulfamoylphenyl)-3-hydroxyphthalimidine, 1-Oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline, Chlorthalidone (USP), Chlorthalidone [USAN:INN:BAN], HSDB 3035, EINECS 201-022-5, NSC 69200, Chlortalidone (JAN/INN), Benzenesulfonamide, 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)-, BRN 0312295, Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-, MLS000069531, CHEBI:3654, JIVPVXMEBJLZRO-UHFFFAOYSA-N, 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide, NSC-69200, SMR000058635, 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide, DSSTox_CID_2812, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide, DSSTox_RID_76738, DSSTox_GSID_22812, W-104322, 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide, SR-01000721929, Chlorthalidone [USAN:USP], Oksodolin, CAS-77-36-1, NCGC00016317-01, Prestwick_759, Chlortalidone [INN], Regroton (Salt/Mix), Combipres (Salt/Mix), Spectrum_000146, Opera_ID_138, AC1L1ECB, (.+/-.)-Hygroton, Prestwick0_000351, Prestwick1_000351, Prestwick2_000351, Prestwick3_000351, Spectrum2_000099, Spectrum3_000349, Spectrum4_000957, Spectrum5_000743, D09NIA, (.+/-.)-Chlorthalidone, CHEMBL1055, SCHEMBL26234, BSPBio_000441, BSPBio_002017, KBioGR_001574, KBioSS_000626, 5-22-07-00602 (Beilstein Handbook Reference), Chlorthalidone (Chlortalidone), DivK1c_000731, SPECTRUM1500187, SPBio_000058, SPBio_002362, AC1Q558X, BPBio1_000487, GTPL7147, DTXSID4022812, BDBM25900, CTK8F8619, HMS502E13, KBio1_000731, KBio2_000626, KBio2_003194, KBio2_005762, KBio3_001237, KS-00000FWZ, MolPort-002-736-049, NINDS_000731, HMS1569G03, HMS1920M09, HMS2091E12, HMS2096G03, HMS2236D07, HMS3259H04, HMS3372A07, HMS3713G03, Pharmakon1600-01500187, BCP27835, NSC69200, Tox21_110369, CCG-38917, NSC756692, STK686335, Chlortalidone 1.0 mg/ml in Methanol, AKOS005599810, Tox21_110369_1, API0001976, CS-2290, DB00310, KS-1342, MCULE-6661021422, NC00690, NSC-756692, VZ31574, IDI1_000731, NCGC00094616-01, NCGC00094616-02, NCGC00094616-03, NCGC00094616-04, NCGC00094616-07, AC-11367, AN-23909, CC-25734, CPD000058635, H530, HY-15833, LS-31408, SAM002589983, ST088141, SBI-0051313.P003, AB0007445, AX8121003, KB-229744, ST2409846, 4CH-007156, AB00051946, FT-0602965, D00272, AB00051946_12, 036C257, C-20285, I06-0208, SR-01000721929-2, SR-01000721929-3, BRD-A26384407-001-05-3, BRD-A26384407-001-15-2, 2-chloro-5-(1-hydroxy-3-oxoisoindolinyl)benzenesulfonamide, A3836/0162845, 2-Chloro-5(1-hydroxy-3-oxo-1-isoindolinyl) benzenesulfonamide, 2-Chloro-5-(1-hydroxy-3-oxo-1H-isoindolinyl)benzenesulfonamide, Chlorthalidone, European Pharmacopoeia (EP) Reference Standard, 2-chloro-5-(1,3-dihydroxy-1H-isoindol-1-yl)benzene-1-sulfonamide, 2-chloro-5-(1-hydroxy-3-oxo-isoindolin-1-yl)benzenesulfonamide, Benzenesulfonamide,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-, Chlorthalidone, United States Pharmacopeia (USP) Reference Standard, 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide #, Chlortalidone for peak identification, European Pharmacopoeia (EP) Reference Standard


ID: 1073

chemical graph of compound 1073



InChIKey: JIVSXRLRGOICGA-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5887
synonyms found at PubChem are:
PROMAZINE HYDROCHLORIDE, 53-60-1, Promazine Hcl, Starazin, Talofen, Promazine (hydrochloride), Promazine monohydrochloride, UNII-U16EOR79U4, RP 4560, Chlorowodorek promazyny [Polish], EINECS 200-179-7, NSC 17468, N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine hydrochloride, Promazine hydrochloride [USP], AI3-28022, MLS000069671, U16EOR79U4, N-(3-(Dimethylamino)propyl)phenothiazine hydrochloride, 10-(3-(Dimethylamino)propyl)phenothiazine hydrochloride, 10-(3-(Dimethylamino)propyl)phenothiazine monohydrochloride, 10-(gamma-Dimethylamino-n-propyl)phenothiazine hydrochloride, Phenothiazine, 10-(3-(dimethylamino)propyl)-, hydrochloride, SMR000058499, Sparine (TN), DSSTox_CID_26949, DSSTox_RID_82026, DSSTox_GSID_46949, Promazine hydrochloride (USP), 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride, Phenothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride, 10-H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1), CHEBI:8460, Chlorowodorek promazyny, CAS-53-60-1, SR-01000000228, NCGC00015829-02, N-[3-(Dimethylamino)propyl]phenothiazine hydrochloride, 10-(3-[Dimethylamino]propyl)phenothiazine hydrochloride, 10-[3-(Dimethylamino)propyl]phenothiazine hydrochloride, Esparinal, Verofen, Promazine hydrochloride [USAN], SR-01000000228-4, Promazine chloride, Prestwick_974, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride, Opera_ID_41, AC1L1LCL, Propazin (pharmaceutical), REGID_for_CID_5887, MLS001148436, MLS002222285, SCHEMBL123418, SPECTRUM1500509, CHEMBL1200469, DTXSID4046949, CTK8G2591, BBC/790, MolPort-003-666-271, HMS1570K07, HMS1920L14, Pharmakon1600-01500509, HY-B1225, KS-000018AN, NSC17468, Tox21_110235, Tox21_500961, CCG-40284, MFCD00058535, NSC-17468, NSC757300, AKOS015964305, Tox21_110235_1, API0003941, CS-4873, KS-1384, LP00961, NSC-757300, NCGC00015829-12, NCGC00094262-01, NCGC00094262-02, NCGC00094262-03, NCGC00094262-04, NCGC00094262-05, NCGC00261646-01, AC-18101, AN-41648, U457, AX8149146, KB-258428, LS-105498, EU-0100961, FT-0674047, ST24031269, WLN: T C666 BN ISJ B3N1&1 &GH, D00797, P 6656, SR-01000000228-2, SR-01000000228-8, W-105721, 10-(3-Dimethylaminopropyl)phenothiazine hydrochloride, Z2784093694, Promazine hydrochloride, VETRANAL(TM), analytical standard, 10-(.gamma.-Dimethylamino-n-propyl)phenothiazine hydrochloride, dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine hydrochloride, N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine hydrochloride, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine hydrochloride, Promazine Hydrochloride 1.0 mg/ml in Methanol (as free base), N,N-Dimethyl-3-(10H-phenothiazin-10-yl)propan-1-aminehydrochloride, N,N-Dimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine hydrochloride, Promazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Promazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 10-(3- paragraph signthorn(1/4)x>>u degrees +/-+/-u>>u).Oaca masculine NIEaNI, AC1LCWAL, AKOS026749940, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-,monohydrochloride, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine; hydron; chloride, 10-(3-dimethylaminopropyl)phenothiazinium chloride


ID: 1074

chemical graph of compound 1074



InChIKey: JJCQSGDBDPYCEO-XVZSLQNASA-N
SMILES: C1C[C@H]([C@H](O[C@@H]1CN)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 470999
synonyms found at PubChem are:
dibekacin, Panamicin, Dideoxykanamycin B, 34493-98-6, 3',4'-Dideoxykanamycin B, Debecacin, Orbicin, UNII-45ZFO9E525, Dibekacin sulfate, BRN 1441606, Dibekacina, Dibekacine, Dibekacinum, Kappati, CHEBI:37945, 45ZFO9E525, Dibekacine [INN-French], Dibekacinum [INN-Latin], Dibekacina [INN-Spanish], DKB, DKM, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-6))-2-deoxy-L-streptamine, EINECS 252-064-6, (1R,2S,3S,4R,6S)-4,6-diamino-3-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-(1-4)-2-deoxy-, Dibekacin [INN:BAN], Dibekacin (INN), Spectrum_001398, AC1LAM6L, Spectrum2_001528, Spectrum3_000960, Spectrum4_001074, Spectrum5_001613, NCGC00095276-01, DSSTox_CID_2915, AC1Q4UA9, DSSTox_RID_76787, DSSTox_GSID_22915, SCHEMBL49816, KBioGR_001428, KBioSS_001878, SPBio_001316, CHEMBL560976, DTXSID2022915, KBio2_001878, KBio2_004446, KBio2_007014, KBio3_002060, JJCQSGDBDPYCEO-XVZSLQNASA-N, HY-B1129, ZINC8214383, Tox21_111496, AC-315, AKOS025402025, CCG-213771, CS-4725, BC226561, CAS-34493-98-6, D07811, AB01563356_01, (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol, 84D


ID: 1075

chemical graph of compound 1075



InChIKey: JJCWKVUUIFLXNZ-UHFFFAOYSA-M
SMILES: C[N+](C)(C)CCO.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 74724
synonyms found at PubChem are:
Choline Bromide, 1927-06-6, Choline, bromide, UNII-CXC75P7WK9, (2-hydroxyethyl)trimethylazanium bromide, CXC75P7WK9, (2-Hydroxyethyl)trimethylammonium bromide, 2-hydroxyethyl(trimethyl)azanium bromide, NCGC00015219-03, AC1L2MIV, AC1Q1RJZ, ACMC-1BVV7, AC1O4X4J, Choline-methyl-13C bromide, DSSTox_CID_28938, DSSTox_RID_83204, DSSTox_GSID_49012, SCHEMBL192988, CHEMBL1256479, DTXSID6049012, CTK4E1061, JJCWKVUUIFLXNZ-UHFFFAOYSA-M, HMS3260D21, EINECS 217-660-2, Tox21_113514, Tox21_500180, ANW-13562, NSC293906, AKOS015833071, CCG-221484, LP00180, NSC-293906, NCGC00093659-01, NCGC00260865-01, Trimethyl(2-hydroxyethyl)ammonium bromide, CAS-1927-06-6, TR-032210, EU-0100180, C 1754, J-012465, N-(2-hydroxyethyl)-N,N,N-trimethylammonium bromide, SR-01000075745-1, F8881-3843, Ethanaminium,2-hydroxy-N,N,N-trimethyl-, bromide (1:1)


ID: 1076

chemical graph of compound 1076



InChIKey: JJSVXWKQLGHFES-QGZYWIHFSA-N
SMILES: CC1C(C(C(C(O1)O[C@H]2CC[C@@]3(C4[C@@H](C[C@@]5([C@H](CC[C@@]5(C4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)OC(=O)C)C=O)O)OC)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708535
synonyms found at PubChem are:
SARMENTOSIDE B, Spectrum_000633, SpecPlus_000060, Spectrum2_000355, Spectrum3_000109, Spectrum4_001391, Spectrum5_000122, AC1O8FC6, BSPBio_001698, KBioGR_001742, KBioSS_001113, SPECTRUM100568, DivK1c_006156, SPBio_000449, CHEMBL3039304, KBio1_001100, KBio2_001113, KBio2_003681, KBio2_006249, KBio3_000818, CCG-38630, SDCCGMLS-0066300.P001, NCGC00179076-01, [(3S,5S,10S,11R,13R,14S,17R)-3-(5-acetyloxy-3-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-10-formyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl] acetate


ID: 1077

chemical graph of compound 1077



InChIKey: JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES: C(CN)CNCCSP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2141
synonyms found at PubChem are:
amifostine, 20537-88-6, Ethiofos, Gammaphos, Ethyol, Sapep, Apaetp, Aminopropylaminoethyl thiophosphate, WR 2721, 2-(3-Aminopropylamino)ethyl thiophosphate, Amifostina, NSC-296961, AU-95722, YM-08310, UNII-ILA426L95O, Amifostine Ethiofos, NSC296961, Amifostinum, C5H15N2O3PS, Amifostine [USAN:INN:BAN], WR-2721, NSC 296961, S-(2-(3-Aminopropylamino)ethyl) phosphorothioate, BRN 2088122, CHEBI:2636, ILA426L95O, JKOQGQFVAUAYPM-UHFFFAOYSA-N, 2-(3-aminopropylamino)ethylsulfanylphosphonic acid, WR 2721C, S,2-(3-Aminopropylamino)ethyl-phosphorothioic acid, S-2-(3-Aminopropylamino)ethyl phosphorothioic acid, NCGC00015073-02, S-omega-(3-Aminopropylamino)ethyl dihydrogen phosphorothioate, S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate, Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique [French], DSSTox_CID_2585, Ethiofos Anhydrous, DSSTox_RID_76644, DSSTox_GSID_22585, S-2-(3-aminopropylamino)-ethylphosphorothioic acid, S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate, Phosphorothioic acid, S-(2-(3-aminopropylamino)ethyl) ester, Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate, CAS-20537-88-6, S-[2-(3-Aminopropylamino)ethyl] phosphorothioate, SR-01000075680, YM 08310, S-[2-[(3-Aminopropyl)amino]ethyl] dihydrogen phosphorothioate, CCRIS 9316, HSDB 7560, Amifostine,(S), Spectrum_000332, SpecPlus_000647, Spectrum5_001920, Lopac-A-5922, D06CIE, NCIMech_000622, S 8744, AC1L1D0F, CHEMBL1006, Lopac0_000029, SCHEMBL18464, KBioSS_000812, MLS000028473, BIDD:GT0059, DivK1c_006743, DTXSID8022585, CTK8F7705, KBio1_001687, KBio2_000812, KBio2_003380, KBio2_005948, Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique, 63717-27-1 (monohydrate), MolPort-003-666-801, HMS2090I03, HMS3260E19, HMS3713C06, Pharmakon1600-01503081, 2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester, BCP08957, HY-B0639, KS-00001F8B, Phosphorothioic acid, S-[2-[(3-aminopropyl)amino]ethyl] ester, WR-2721C, Tox21_110077, Tox21_500029, CCG-35734, Ethanethiol, 2-[(3-aminopropyl)amino]-, 1-(dihydrogen phosphate), NSC758236, ZINC21992285, AKOS015895196, Tox21_110077_1, AC-1126, API0001443, CS-2875, DB01143, LP00029, NSC-758236, RL02548, WR-1064, SMP2_000335, 59178-37-9 (di-hydrochloride salt), NCGC00015073-01, NCGC00015073-03, NCGC00015073-04, NCGC00015073-05, NCGC00093549-01, NCGC00093549-02, NCGC00260714-01, AN-15218, AS-13020, BC215613, Ethanethiol, dihydrogen phosphate (ester), NCI60_002485, SC-18798, SMR000058413, Ethanethiol, dihydrogen phosphate- (ester), SBI-0050018.P003, AB0012846, LS-108362, EU-0100029, FT-0622272, 37A886, A 5922, C06819, [2-(3-aminopropylamino)ethylthio]phosphonic acid, 33870-EP2275420A1, 33870-EP2295055A2, 33870-EP2295416A2, 33870-EP2295426A1, 33870-EP2295427A1, 33870-EP2298748A2, 33870-EP2298764A1, 33870-EP2298765A1, 33870-EP2305642A2, 33870-EP2311453A1, 33870-EP2311808A1, 33870-EP2311829A1, AB00053311-04, AB00053311-05, AB00053311_06, A814662, {S-[2-(3-Aminopropylamino)ethyl]} phosphorothioate, 2-(3-azanylpropylamino)ethylsulfanylphosphonic acid, I06-0333, J-013390, J-519582, SR-01000075680-1, SR-01000075680-3, SR-01000075680-5, 2-(3-Aminopropyl)aminoethyl phosphorothioate; WR2721, BRD-K73947551-001-01-0, ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid, 2-(3-aminopropylamino)ethylsulfanylphosphonic acid,trihydrate, Phosphorothioic acid, S-[2-[(3-aminopropyl)amino]ethyl]ester, S-2-(3-aminopropylamino)ethyl O,O-dihydrogen phosphorothioate, {S-[2-[(3-Aminopropyl)amino]ethyl]} dihydrogen phosphorothioate, 2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester (9CI), Ethanethiol, {S-[(3-aminopropyl)amino]-,} dihydrogen phosphate- (ester), 53028-04-9


ID: 1078

chemical graph of compound 1078



InChIKey: JLIDBLDQVAYHNE-LXGGSRJLSA-N
SMILES: CC1=CC(=O)CC(C1(/C=C/C(=C\C(=O)O)/C)O)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5375199
synonyms found at PubChem are:
ABSCISIC ACID, 14375-45-2, (+/-)-Abscisic acid, Abscisinsaeure, Abszisinsaeure, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid, acido abscisico, acide abscissique, (+)-Abscisic acid, 2-cis-abscisic acid, (RS)-Abscisic acid, Dormin, CHEBI:22152, JLIDBLDQVAYHNE-LXGGSRJLSA-N, 2-cis,4-trans-Abscisic acid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-enyl)-3-methylpenta-2,4-d ienoic acid, abscisic acids, PBI-57, (+/-)-Aba, ABA, (+/-)-(cis,Trans)-abscisic acid, ( inverted exclamation markA)-Abscisic acid, Abscisic acid, (+/-)-(2Z,4E)-, Abscisic acid (ABA), AC1NT9EJ, Abscisic acid (+/-)-cis,trans-form [MI], Spectrum5_000342, (+)-Abscisic acid 99%, DSSTox_CID_10604, DSSTox_RID_78851, DSSTox_GSID_30604, BSPBio_002916, SPECTRUM1502234, CHEMBL379808, Jsp004339, DTXSID1030604, CHEBI:62431, MolPort-003-665-998, HMS1921N10, Pharmakon1600-01502234, (+)-2-cis,4-trans-abscisic acid, (2Z,4E)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentadienoic acid, 5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXO-2-CYCLOHEXEN-1-YL]-3-METHYL-2Z,4E-PENTADIENOIC ACID, Tox21_201137, CA-722, CCG-38879, MFCD00066545, NSC759648, SBB003072, AKOS015903032, AN-1423, NSC-759648, SDCCGMLS-0066860.P001, NCGC00017240-02, NCGC00017240-03, NCGC00017240-04, NCGC00017240-05, NCGC00017240-06, NCGC00017240-07, NCGC00091094-01, NCGC00091094-02, NCGC00091094-03, NCGC00091094-04, NCGC00258689-01, 2,4-pentadienoic acid, 5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-, (2Z,4E)-, 4CN-2982, L903, SC-16385, ST056307, CAS-14375-45-2, KB-206885, LS-190476, LS-190722, LS-194449, 4CH-024069, A0792, FT-0082739, 2-cis,4-trans-Abscisic acid, synthetic, 98%, 375A452, J-007868, 13F617B4-6D52-4DAF-ADA1-A7FE2B84E828, (+/-)-Abscisic acid, BioReagent, plant cell culture tested, >=98.5% (HPLC), (2Z,4E)-3-Methyl-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexenyl)-2,4-pentadienoic acid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-cyclohex-2-en-1-yl)-3-methyl-penta-2,4-dienoic acid, (2Z,4E)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoicacid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-enyl)-3-methylpenta-2,4-dienoic acid, (4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid


ID: 1079

chemical graph of compound 1079



InChIKey: JLKIGFTWXXRPMT-UHFFFAOYSA-N
SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5329
synonyms found at PubChem are:
sulfamethoxazole, 723-46-6, Gantanol, Sulphamethoxazole, Sulfisomezole, Sulfamethoxazol, Metoxal, Sulfamethylisoxazole, Simsinomin, Radonil, Sinomin, Sulphamethoxazol, 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, Sulpha-methoxizole, Sulfamethalazole, Azo-gantanol, Sulphamethylisoxazole, Urobak, Sulfamethoxizole, 3-Sulfanilamido-5-methylisoxazole, Gantanol-DS, 4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide, Bactrimel, Gamazole, Sulfametoxazol, Sulphisomezole, Solfametossazolo, Sulfamethoxazolum, 5-Methyl-3-sulfanilamidoisoxazole, Ro 4-2130, MS 53, 3-Sulphanilamido-5-methylisoxazole, 5-Methyl-3-sulphanil-amidoisoxazole, 3-(p-Aminophenylsulfonamido)-5-methylisoxazole, Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, 5-Methyl-3-sulfanylamidoisoxazole, Azo gantanol, N'-(5-Methyl-3-isoxazolyl)sulfanilamide, N1-(5-Methyl-3-isoxazolyl)sulfanilamide, N'-(5-Methylisoxazol-3-yl)sulphanilamide, 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide, Solfametossazolo [DCIT], 3-(para-Aminophenylsulphonamido)-5-methylisoxazole, Sulfametoxazol [INN-Spanish], Sulfamethoxazolum [INN-Latin], Septran, Trib, Sulphamethalazole, A047, Sulfamethoxazole sodium, UNII-JE42381TNV, Apo-Sulfamethoxazole, CCRIS 567, N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide, CHEBI:9332, N'-(5-Methyl-3-isoxazole)sulfanilamide, HSDB 3186, Ro 6-2580/11, Sulfamethoxazole [USAN:INN:JAN], Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-, Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-, Sulphamethoxazole BP 98, EINECS 211-963-3, SMX, CHEMBL443, NSC 147832, BRN 0226453, 4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide, MLS000069732, JE42381TNV, 4-AMINO-N-(5-METHYL-3-ISOXAZOYL)BENZENESULFONAMIDE, 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide, C10H11N3O3S, N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide, 5-Methyl-3-sulfonylamidoisoxazole, JLKIGFTWXXRPMT-UHFFFAOYSA-N, N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide, Sulfanilamide, N(1)-(5-methyl-3-isoxazolyl)-, ALBB-002089, NSC147832, NCGC00016533-05, NCGC00186654-01, CAS-723-46-6, N1-(5-Methylisoxazol-3-yl)sulfanilamide, SMR000058223, DSSTox_CID_6064, 3-(p-Aminobenzenesulfonamido)-5-methylisoxazole, DSSTox_RID_78001, DSSTox_GSID_26064, 4-Amino-N-[5-methyl-3-isoxazolyl]benzenesulfonamide, [(4-aminophenyl)sulfonyl](5-methylisoxazol-3-yl)amine, 4-Amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide, N1-(5-methylisoxazol-3-yl)-4-aminobenzene-1-sulfonamide, 129378-89-8, SR-01000000217, Gantanol DS, Sulphameth oxazole, DRG-0031, Prestwick_453, Septrin (TN), Septran (Salt/Mix), Septrin (Salt/Mix), Sulfamethoxazole,(S), Eusaprim (Salt/Mix), Spectrum_000994, Sulfamethoxazole(USAN), Opera_ID_882, Maybridge1_007190, Prestwick0_000177, Prestwick1_000177, Prestwick2_000177, Prestwick3_000177, Spectrum2_000788, Spectrum3_000584, Spectrum4_000345, Spectrum5_000982, Sulfamethoxazole [USAN:USP:INN:BAN:JAN], D0AE2X, D0R9OH, Epitope ID:114999, Co-trimoxazole (Salt/Mix), AC1Q2J5R, SCHEMBL3656, Oprea1_114486, Oprea1_285680, BSPBio_000073, BSPBio_002028, KBioGR_000749, KBioSS_001474, KSC635S5T, MLS001055354, MLS001074165, MLS006011871, BIDD:GT0731, DivK1c_000649, SPECTRUM1500550, SPBio_000896, SPBio_001994, AC1L1K42, ARONIS018156, BPBio1_000081, DTXSID8026064, component of Bactrim (Salt/Mix), CTK5D5959, HMS502A11, HMS561O18, JLKIGFTWXXRPMT-UHFFFAOYSA-, KBio1_000649, KBio2_001474, KBio2_004042, KBio2_006610, KBio3_001528, KS-00004AEJ, ZINC89763, EBD3403, WLN: T5NOJ C1 EMSWR DZ, MolPort-000-145-787, NINDS_000649, HMS1568D15, HMS1921A21, HMS2092K03, HMS2095D15, HMS2233L13, HMS3259E06, HMS3372M22, HMS3655O22, HMS3712D15, Pharmakon1600-01500550, BCP02881, HY-B0322, KS-000000QU, Sulfamethoxazole (JP15/USP/INN), Sulfamethoxazole (JP17/USP/INN), Sulfamethoxazole, analytical standard, Tox21_110480, Tox21_200353, ANW-43073, BBL004554, BDBM50029770, CCG-40166, HTS001394, KM1475, MFCD00010546, NSC757328, Ro-42130, s1915, SBB057675, SBB071655, STK007988, AKOS000200952, component of Azo Gantanol (Salt/Mix), Tox21_110480_1, BS-3542, CS-2363, DB01015, LS-1620, MCULE-1450176600, NC00537, NSC-147832, NSC-757328, Ro-4-2130, RTR-023663, TRA0076970, IDI1_000649, NCGC00016533-01, NCGC00016533-02, NCGC00016533-03, NCGC00016533-04, NCGC00016533-06, NCGC00016533-07, NCGC00016533-08, NCGC00016533-09, NCGC00016533-10, NCGC00016533-11, NCGC00016533-12, NCGC00016533-14, NCGC00021995-03, NCGC00021995-04, NCGC00021995-05, NCGC00257907-01, AC-11118, AN-22110, BAS 00836086, CPD000058223, H463, KB-97587, SAM002554930, SC-15160, ST024740, BCP0726000283, N'-(5-Methyl-3-isoxazolyl)-Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-Sulfanilamide, N1-(5-Methyl-3-isoxazolyl)sulphanilamide, SBI-0051524.P003, AB1009297, ST2418109, TL8005058, AB00052099, BB 0242379, FT-0602616, N(1)-(5-Methyl-3-isoxazolyl)sulphanilamide, N^1-(5-Methyl-3-isoxazolyl)-Sulfanilamide, S0361, ST51006798, C07315, D00447, J10090, 4-[N-(5-Methylisoxazol-3-yl)sulphamoyl]aniline, AB00052099-14, AB00052099-16, AB00052099_17, AB00052099_18, Ndimethyl1-(5-methyl-3-isoxazolyl)-Sulfanilamide, I01-0154, Q-201762, SR-01000000217-2, SR-01000000217-3, Sulfamethoxazole, VETRANAL(TM), analytical standard, Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI), Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-(8CI), 4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide, BRD-K28494619-001-05-0, BRD-K28494619-001-15-9, BRD-K28494619-001-26-6, Z57198677, 4-Amino-N-(5-methyl-isoxazol-3-yl)-benzene sulfonamide, 4-AMINO-N-[5-METHYL-3-ISOXAZOLYL]BENZENESULFONAMID, Sulfamethoxazole, certified reference material, TraceCERT(R), SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE), Sulfamethoxazole, European Pharmacopoeia (EP) Reference Standard, Sulfamethoxazole, United States Pharmacopeia (USP) Reference Standard, SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE); TMP/SMX (MIXTURE)), Sulfamethoxazole, Pharmaceutical Secondary Standard; Certified Reference Material, 08D, 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; N1-(5-Methylisoxazol-3-yl)sulfanilamide, InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)


ID: 1080

chemical graph of compound 1080



InChIKey: JLPYLHLUHJOPNL-UHFFFAOYSA-N
SMILES: CC1=C(N(C2=C1C=C(C=C2)F)CC3=CC=C(C=C3)Cl)CC(C)(C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 122070
synonyms found at PubChem are:
L-655,240, 103253-15-2, L-655240, CHEMBL362223, JLPYLHLUHJOPNL-UHFFFAOYSA-N, 1-((4-chlorophenyl)methyl)-5-fluoro-a,a-3-trimethyl-(1h)-indole-2-propanoic acid, 3-[1-(4-Chlorobenzyl)-5-fluoro-3-methyl-indol-2-yl]-2,2-dimethyl propanoic acid, SR-01000075967, L 655240, Tocris-1698, Lopac-L-9539, D0I9JH, AC1L3TX4, Lopac0_000670, SCHEMBL3252820, CHEBI:93563, CTK8E8278, MolPort-003-958-591, HMS3268O17, ZINC2526554, BDBM50168772, AKOS024456751, CCG-204756, 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid, NCGC00015618-01, NCGC00015618-02, NCGC00025263-01, KB-146245, RT-013481, B6834, EU-0100670, L 9539, L000335, J-000915, SR-01000075967-1, SR-01000075967-3, BRD-K89402695-001-01-5, 1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoic acid, 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-5-fluoro-alpha,alpha,3-trimethyl-, 3-[1-(4-Chloro-benzyl)-5-fluoro-3-methyl-1H-indol-2-yl]-2,2-dimethyl-propionic acid, 3-[1-(4-chlorobenzyl)-3-methyl-5-fluoroindol-2-yl]-2,2-dimethyl propanoic acid, 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methylindol-2-yl]-2,2-dimethylpropanoic acid, L-655,240|1-[(4-Chlorophenyl)methyl]-5-fluoro-?,?,3-trimethyl-1H-indole-2-propanoic acid


ID: 1081

chemical graph of compound 1081



InChIKey: JLQNXWHJIQWBMH-UHFFFAOYSA-N
SMILES: C1=CC=[N+]2C(=C1)C=C(C3=C2C(=CC=C3)Cl)O.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 9795307
synonyms found at PubChem are:
CHEMBL175225, SCHEMBL2081163, SCHEMBL2081165, 10-chloro-6-hydroxybenzo [c]quinolizinium chloride


ID: 1082

chemical graph of compound 1082



InChIKey: JLRGJRBPOGGCBT-UHFFFAOYSA-N
SMILES: CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5505
synonyms found at PubChem are:
tolbutamide, 64-77-7, Orinase, Artosin, Tolbutamid, Aglicid, Arkozal, Diabetol, Dolipol, Rastinon, Tolumid, Diaben, Orabet, 1-Butyl-3-tosylurea, Willbutamide, Butamide, Diabetamid, Diabuton, Diasulfon, Dirastan, Glyconon, Ipoglicone, Pramidex, Tolbusal, Artozin, Butamid, Drabet, Mobenol, Oralin, Orezan, Orinaz, Oterben, Toluina, Toluvan, Tolylsulfonylbutylurea, Sk-tolbutamide, 1-Butyl-3-(p-tolylsulfonyl)urea, Tolbutamida, Tolbutamidum, N-n-Butyl-N'-tosylurea, N-Butyl-N'-(p-tolylsulfonyl)urea, 1-Butyl-3-(p-methylphenylsulfonyl)urea, 1-p-Toluenesulfonyl-3-butylurea, Beglucin, Butamidum, Diabesan, Tarasina, Tolbutone, Arcosal, Tolbet, 3-(p-Tolyl-4-sulfonyl)-1-butylurea, N-Butyl-N'-p-toluenesulfonylurea, N-(Butylcarbamoyl)-4-methylbenzenesulfonamide, N-(4-Methylphenylsulfonyl)-N'-butylurea, N-Butyl-N'-(4-methylphenylsulfonyl)urea, Orinase (TN), N-(4-Methylbenzenesulfonyl)-N'-butylurea, HLS 831, Apo-Tolbutamide, N-(p-Tolylsulfonyl)-N'-butylcarbamide, N-(Sulfonyl-p-methylbenzene)-N'-N-butylurea, Tolbutamidum [INN-Latin], Benzenesulfonamide, N-[(butylamino)carbonyl]-4-methyl-, Tolbutamida [INN-Spanish], NCI-C01763, N-4-Methylbenzolsulfonyl-N-butylurea, toluran, D 860, Urea, 1-butyl-3-(p-tolylsulfonyl)-, Oramide, Restinon, Tolumide, Novo-Butamide, 3-butyl-1-(4-methylbenzenesulfonyl)urea, N-Butyl-N'-toluene-p-sulfonylurea, UNII-982XCM1FOI, Tol-Tab, CCRIS 592, Tolbutamide [INN:BAN:JAN], N-4-(Methylbenzolsulfonyl)-n-butylurea, 1-Butyl-3-(4-methylphenylsulfonyl)urea, N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide, TOLBUTAMIDE USP, C12H18N2O3S, HSDB 3393, EINECS 200-594-3, NSC 23813, U 2043, 3-[p-Tolyl-4-sulfonyl]-1-butylurea, CHEMBL782, 1-butyl-3-(4-methylphenyl)sulfonylurea, BRN 1984428, 982XCM1FOI, N-(p-Methylbenzenesulfonyl)-N'-butylurea, Benzenesulfonamide, N-((butylamino)carbonyl)-4-methyl-, N-(Sulfonyl-p-methylbenzene)-N'-butylurea, MLS000028399, CHEBI:27999, 3-(p-tolylsulfonyl)-1-butylurea, JLRGJRBPOGGCBT-UHFFFAOYSA-N, N-((Butylamino)carbonyl)-4-methylbenzenesulfonamide, N-(p-tolylsulfonyl)-N'-n-butylurea, 1-Butyl-3-(para-tolylsulfonyl) urea, CAS-64-77-7, NCGC00015999-10, SMR000058363, 3-butyl-1-[(4-methylbenzene)sulfonyl]urea, DSSTox_CID_1359, T 0891, 1-BUTYL-3-(4-METHYLBENZENESULFONYL)UREA, DSSTox_RID_76106, DSSTox_GSID_21359, Diaval, Tolbutamid R.A.N., SR-01000003059, (butylamino)-N-[(4-methylphenyl)sulfonyl]carboxamide, Tolbutamide [USP:INN:BAN:JAN], Prestwick_471, PubChem18102, Spectrum_000447, Opera_ID_112, Tolbutamide Pfizer Brand, AC1L1KHP, Prestwick0_000190, Prestwick1_000190, Prestwick2_000190, Prestwick3_000190, Spectrum2_001210, Spectrum3_000599, Spectrum4_000358, Spectrum5_001272, Tolbutamide Aventis Brand, Tolbutamide Hoechst Brand, Lopac-T-0891, Tolbutamide Butamide Brand, N-n-Butyl-N''-tosylurea, D06OIV, WLN: 4MVMSWR D1, AC1Q2X3T, Apotex Brand of Tolbutamide, Pfizer Brand of Tolbutamide, Tolbutamide, 98% 10g, Aventis Brand of Tolbutamide, Hoechst Brand of Tolbutamide, NCIOpen2_009592, BIDD:PXR0179, CBiol_001920, Lopac0_001154, SCHEMBL15918, BSPBio_000119, BSPBio_001507, BSPBio_002078, KBioGR_000227, KBioGR_000795, KBioGR_002275, KBioSS_000227, KBioSS_000927, KBioSS_002276, 4-11-00-00396 (Beilstein Handbook Reference), Butamide Brand of Tolbutamide, MLS001148399, MLS002152944, Toluina|||Tolumid|||Orinase, DivK1c_000341, SPECTRUM1500581, R.A.N. Brand of Tolbutamide, SPBio_001000, SPBio_002040, BPBio1_000131, GTPL6848, Valdecasas Brand of Tolbutamide, Yamanouchi Brand of Tolbutamide, Tolbutamide (JP15/USP/INN), Tolbutamide (JP17/USP/INN), Tolbutamide, analytical standard, DTXSID8021359, HMS501B03, KBio1_000341, KBio2_000227, KBio2_000927, KBio2_002275, KBio2_002795, KBio2_003495, KBio2_004843, KBio2_005363, KBio2_006063, KBio2_007411, KBio3_000453, KBio3_000454, KBio3_001578, KBio3_002755, KS-00000XIN, BerlinChemie Brand of Tolbutamide, cMAP_000008, MolPort-001-783-540, NINDS_000341, Bio1_000206, Bio1_000695, Bio1_001184, Bio2_000227, Bio2_000707, HMS1361L09, HMS1568F21, HMS1791L09, HMS1989L09, HMS2089C17, HMS2092M21, HMS2095F21, HMS2232H16, HMS3259A08, HMS3263H09, HMS3402L09, HMS3651N03, HMS3712F21, Pharmakon1600-01500581, Berlin-Chemie Brand of Tolbutamide, BCP09192, HY-B0401, NSC23813, ZINC1530703, N-Butyl-N''-(p-tolylsulfonyl)urea, Tox21_110279, Tox21_201612, Tox21_302795, Tox21_501154, BDBM50027886, CCG-39141, LS-278, MFCD00027169, NSC-23813, NSC757354, s2443, SBB058188, 1-Butyl-3-(para-tolylsulfonyl)-urea, AKOS015894999, Tox21_110279_1, 1-(p-toluenesulfonyl)-3-n-butyl-urea, CS-2500, DB01124, LP01154, MCULE-9720356859, NC00543, NE30724, NSC-757354, Tolbutamide 1.0 mg/ml in Acetonitrile, IDI1_000341, IDI1_033977, N-(n-Butyl)-N'-p-toluene-sulfonylurea, NCGC00015999-01, NCGC00015999-02, NCGC00015999-03, NCGC00015999-04, NCGC00015999-05, NCGC00015999-06, NCGC00015999-07, NCGC00015999-08, NCGC00015999-09, NCGC00015999-11, NCGC00015999-12, NCGC00015999-13, NCGC00015999-14, NCGC00015999-15, NCGC00015999-16, NCGC00015999-17, NCGC00015999-19, NCGC00022721-03, NCGC00022721-04, NCGC00022721-05, NCGC00022721-06, NCGC00022721-07, NCGC00022721-08, NCGC00022721-09, NCGC00022721-10, NCGC00256548-01, NCGC00259161-01, NCGC00261839-01, AC-12490, AJ-26683, AN-16594, AS-14136, CPD000058363, K045, KB-81177, SAM002554936, SC-17768, N-(4-Methylphenylsulfonyl)-N''-butylurea, N-Butyl-N''-(4-methylphenylsulfonyl)urea, SBI-0051121.P003, AB1004876, TL8000121, AB00052110, EU-0101154, FT-0603265, ST24031344, ST50409552, BIM-0051121.0001, C07148, D00380, J10018, U-2043, AB00052110-16, AB00052110_17, AB00052110_18, Tolbutamide, VETRANAL(TM), analytical standard, I05-3340, N-((butylamino) carbonyl)-4-methylbenzenesulfonamide, SR-01000003059-2, SR-01000003059-4, SR-01000003059-7, W-104820, BRD-K85119730-001-06-5, BRD-K85119730-001-17-2, Z44591715, Tolbutamide, European Pharmacopoeia (EP) Reference Standard, 1-(([(Butylamino)carbonyl]amino)sulfonyl)-4-methylbenzene #, Tolbutamide, United States Pharmacopeia (USP) Reference Standard, 100735-34-0


ID: 1083

chemical graph of compound 1083



InChIKey: JLTNCZQNGBLBGO-MOPGFXCFSA-N
SMILES: CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)[C@@H]4[C@H](O3)COC5=CC(=C(C=C45)OC)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 442826
synonyms found at PubChem are:
alpha-Toxicarol, TOXICAROL, 82-09-7, CHEBI:9643, AC1L9DGQ, CHEMBL508992, SCHEMBL4742046, ZINC1684799, LMPK12060027, AKOS032949012, 4CN-2964, C10537


ID: 1084

chemical graph of compound 1084



InChIKey: JLVFQWFTNVMTEG-UHFFFAOYSA-N
SMILES: CN1CCCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 16114
synonyms found at PubChem are:
Homochlorcyclizine, dihydrochloride, SA 97 dihydrochloride, SA-97, NSC 169498, Homochlorcyclizine, hydrochloride (VAN), 1-(p-Chloro-alpha-phenylbenzyl)hexahydro-4-methyl-1H-1,4-diazepine, dihydrochloride, 1-H,4-Diazepine, 1-(p-chloro-alpha-phenylbenzyl)hexahydro-4-methyl-, dihydrochloride, 1H-1,4-Diazepine, 1-(p-chloro-alpha-phenylbenzyl)hexahydro-4-methyl-, dihydrochloride, AC1L27AE, LS-60173, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane-1,4-diium dichloride, Homochlorcyclizine dihydrochloride, 1982-36-1, 1-[P-CHLORODIPHENYLMETHYL]-4-METHYL-1,4-DIAZACYCLOHEPTANE DIHYDROCHLORIDE, Homoclomin (TN), Prestwick_593, AC1LCV91, SCHEMBL1977999, CHEBI:31671, HMS1568J08, AKOS025392035, ACM1982361, API0013627, CCG-220283, Homochlorcyclizine hydrochloride (JP17), FT-0765025, D01460, C-46188, SR-01000000252, SR-01000000252-2, 1-((4-Chlorophenyl)(phenyl)methyl)-4-methyl-1,4-diazepane dihydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane dihydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane;dihydrochloride


ID: 1085

chemical graph of compound 1085



InChIKey: JLYXXMFPNIAWKQ-UHFFFAOYSA-N
SMILES: C1(C(C(C(C(C1Cl)Cl)Cl)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 727
synonyms found at PubChem are:
lindane, beta-HCH, gamma-HCH, gamma-BHC, Hexachlorane, alpha-HCH, Kwell, 1,2,3,4,5,6-Hexachlorocyclohexane, Benzene hexachloride, Hexicide, gamma-hexachlorocyclohexane, beta-BHC, beta-Lindane, Aalindan, Jacutin, Gamene, Gexane, 58-89-9, epsilon-HCH, BETA-HEXACHLOROCYCLOHEXANE, Agrocide, Aparasin, Aphtiria, Chloresene, Codechine, delta-BHC, delta-HCH, Entomoxan, Gammalin, Gammaterr, Hexachloran, Hexaverm, Hexyclan, Kokotine, Lindafor, Lindosep, Lorexane, Nicochloran, Ovadziak, Owadziak, Pedraczak, Pflanzol, Quellada, Streunex, Aficide, Aplidal, Arbitex, Celanex, Devoran, Gamacid, Hortex, Lendine, Lentox, Lidenal, Lindex, Lintox, Linvur, Mszycol, Omnitox, Scabene, Bexol, Nexit, Viton, alpha-Lindane, Hcch, Hexachlorocyclohexane, Agrocide WP, Agrocide III, Ben-Hex, Ameisentod, Benhexol, Gammexane, Heclotox, Lasochron, Lindatox, Gammalin 20, Neo-scabicidol, gamma-Lindane, Nexit-stark, Bentox 10, Milbol 49, Nexen fb, alpha-BHC, Nexol-E, ALPHA-HEXACHLOROCYCLOHEXANE, DOL GRANULE, Gamacarbatox, Lindagrain, Lindagranox, Lindapoudre, Spruehpflanzol, Agronexit, Esoderm, Gallogama, Gamaphex, Geobilan, Hexatox, Hilbeech, Lindagam, Novigam, Silvanol, Gamiso, Inexit, Isotox, Lindan, 319-84-6, 319-85-7, 319-86-8, gamma-col, Spritz-rapidin, Forst-nexen, Sang gamma, Mglawik L, Agrocide 7, Hungaria L7, Ameisenmittel merck, TRI-6, Spritzlindane, Benzanex, DELTA-HEXACHLOROCYCLOHEXANE, Gamacide, Hexablanc, Hexachlor, Hexapoudre, Hexcidum, Beta-1,2,3,4,5,6-hexachlorocyclohexane, Dolmix, Gamtox, Hexamul, Isatox, Submar, Gyben, delta-Lindane, Geolin G 3, Verindal ultra, beta-Hexachloran, TAP 85, Detox 25, 608-73-1, Arcotal S, Trives-T, alpha-Hexachlorane, gamma BHC, Agrocide 6G, Hexachlorcyclohexan, Lacco HI lin, Drilltox-Spezial Aglukon, beta-Benzene hexachloride, Gamacide 20, gamma Benzene hexachloride, gamma-Benzene hexachloride, hecoltox, Hexachlorocyclohexanes, Ameisenatod, Benhexachlor, Gammahexane, alpha-1,2,3,4,5,6-Hexachlorocyclohexane, Aphtitria, Exagama, Gammahexa, Gammallin, Gammaxene, Gammopaz, Lindalo, Lindamul, Lindano, Lindanum, Lindaterra, Novigan, Benzex, beta-Hexachlorobenzene, Forlin, Gammex, Detmol-extrakt, Fenoform forte, gamma-Hexachlorobenzene, nexen-fb, Detmol Extract, Borer Spray, alpha-Hexachloran, alpha-Benzenehexachloride, delta-Benzenehexachloride, .delta.-Lindane, Agrocide 2, ENT 9,234, PMS Lindane, Kwell-R, alpha-Benzene hexachloride, delta-Benzene hexachloride, BHC (insecticide), HCH [BSI], HCH [ISO], .delta.-BHC, Gamma-mean 400, Agrisol G-20, .delta.-Hexachlorocyclohexane, BHC or HCH, t-HCH, Caswell No. 079, Caswell No. 527, gamma-1,2,3,4,5,6-Hexachlorocyclohexane, gamma-Benzohexachloride, ENT 7,796, ENT 9,232, (+)-alpha-HCH, Latka 666, Gammasan, gamma hexachlor, Lindanum [INN-Latin], am eisenatod, beta-isomer, gamma-Benzenehexachloride, gamma-Hexachlorzyklohexan, Hexit, Atlas steward, BHC, HCH, hilbeec h, Latka 666 [Czech], Lindano [INN-Spanish], Benzene hexachloride-alpha-isomer, Sang-gamma, gamma-HCH or gamma-BHC, Lindam ul, New kotol, Eso derm, nexi t-stark, UNII-59NEE7PCAB, UNII-YM80ODM9PD, Rcra waste number U129, gamma-Hexachlorcyclohexanum, Hexachlorocyclohexane, gamma-isomer, Isot ox, Technical HCH, .alpha.-Lindane, C6H6Cl6, gamma-Hexachlorane, zeta-HCH, 6108-10-7, Hexachlorocyclohexane, beta-, Hexachlorcyclohexan [German], ENT 8,601, ENT 9,233, .alpha.-Hexachlorocyclohexane, Hexachlorocyclohexane, alpha-, Hexachlorocyclohexane, delta-, Hexachlorocyclohexane, gamma-, CCRIS 327, CCRIS 328, CCRIS 329, technical Hexachlorocyclohexane, trans-alpha-Benzenehexachloride, .delta.-HCH, HCH (alpha), Benzenehexachloride-alpha-isomer, CCRIS 1449, HSDB 646, HCH (beta), BBH, d-BHC, Benzene hexachloride (Ambiguous), Benzene hexachloride-gamma isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (-)-alpha-HCH, 1a,2a,3b,4a,5b,6b-Hexachlorocyclohexane, gamma-BHC Benhexachlor, HSDB 1606, HSDB 6029, HSDB 6183, HSDB 6184, Benzenehexachloride, mixed isomers, benzene-cis-hexachloride, NCI-C00204, Hexachlorocyclohexane, gamma isomer, Hexachlorocyclohexane (all isomers), Drill tox-spezial aglukon, Murfume grain store smoke, EINECS 200-401-2, EINECS 206-270-8, EINECS 206-271-3, EINECS 206-272-9, EINECS 210-168-9, epsilon-Benzenehexachloride, Hexachlorocyclohexane (mixed isomers), NSC 11808, 59NEE7PCAB, KWELL (TN), YM80ODM9PD, Hexachlorocyclohexane, technical grade, HGI, RCRA waste no. U129, Benzene Hexachloride, gamma, EPA Pesticide Chemical Code 009001, Hexachlorocyclohexane (technical grade), epsilon-Hexachlorocyclohexane, BRN 1907331, BRN 1907334, BRN 1907337, BRN 1907338, BRN 3195880, .delta.-Benzene hexachloride, UNII-YV2D256Z3N, (1alpha,2beta,3alpha,4beta,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, AI3-07796, AI3-08601, AI3-09232, AI3-09233, AI3-09234, YV2D256Z3N, (1r,2r,3r,4r,5r,6r)-1,2,3,4,5,6-hexachlorocyclohexane, Lindane [Hexachlorocyclohexanes], PLK, benzene hexachloride-gamma-isomer, CHEBI:24536, CHEBI:28428, CHEBI:32888, CHEBI:39095, CHEBI:39096, Benzene hexachloride, all isomers, Cyclohexane, beta-1,2,3,4,5,6-hexachloro-, Cyclohexane, delta-1,2,3,4,5,6-hexachloro-, beta-HCH [Hexachlorocyclohexanes], UNII-IVM9A2N49K, JLYXXMFPNIAWKQ-GNIYUCBRSA-N, alpha-HCH [Hexachlorocyclohexanes], gamma-HCH [Hexachlorocyclohexanes], Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-, 1,2,3,4,5,6-Hexachlorocyclohexane, gamma-isomer, delta-(Aeeeee)-1,2,3,4,5,6-hexachlorocyclohexane, EINECS 228-068-9, HCH-.delta., Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.alpha.,6.beta.)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.beta.,6.beta.)-, BHC-.delta. isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, beta-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-isomer, 119911-69-2, BHC, .delta., UNII-5477B350EK, 1,2,3,4,5,6-Hexachlorocyclohexane (mixture of isomers), Cyclohexane, 1,2,3,4,5,6-hexachloro-, (mixed isomers), NCGC00094546-04, 1a,2b,3a,4b,5a,6b-hexachlorocyclohexane, (1R,2R,3R,4R,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2R,3S,4s,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane, 1alpha,2alpha,3beta,4alpha,5alpha,6beta-Hexachlorocyclohexane, AI3-15109, trans-1,2,3,4,5,6-hexachlorocyclohexane, DSSTox_CID_685, DSSTox_CID_686, DSSTox_CID_687, 1-alpha,2-alpha,3-alpha,4-beta,5-alpha,6-beta-Hexachlorocyclohexane, 1-alpha,2-beta,3-alpha,4-beta,5-alpha,6-beta-Hexachlorocyclohexane, HCH, technical grade [Hexachlorocyclohexanes], (1alpha,2alpha,3alpha,4beta,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2beta,3alpha,4beta,5alpha,6beta)-, DSSTox_RID_75733, DSSTox_RID_75734, DSSTox_RID_75735, 1,2,3,4,5,6-Hexachlorocyclohexane gamma isomer, DSSTox_GSID_20685, DSSTox_GSID_20686, DSSTox_GSID_20687, 55963-79-6, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.beta.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, 1,2,3,4,5,6-Hexachlorocyclohexane (all stereo isomers), Cyclohexane, 1,2,3,4,5,6-hexachloro-, .gamma.-isomer, (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2t,3c,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, 1alpha,2alpha,3beta,4alpha,5beta,6beta-Hexachlorocyclohexane, Scabecid, IVM9A2N49K, (1alpha,2alpha,3alpha,4beta,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane, 1,2,3,4,5,6-hexachlorocyclohexane (1alpha,2alpha,3beta,4alpha,5alpha,6beta), 1,2,3,4,5,6-Hexachlorocyclohexane (all stereo isomers, including lindane), gamma-Hexachlorocyclohexane [Lindane and other hexachlorocyclohexane isomers], theta-HCH, CAS-58-89-9, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4beta,5alpha,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4beta,5beta,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-, Cyclohexane, l,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-, 119911-70-5, 6108-11-8, 6108-12-9, CAS-319-85-7, CAS-608-73-1, SMR000857321, SMR000875266, .alpha.-BHC, .gamma.-BHC, 1,2,3,4,5,6-Hexachlorocyclohexane (HCH), .delta.,1,2,3,4,5,6-Hexachlorocyclohexane, 5477B350EK, Cyclohexane, .delta.,1,2,3,4,5,6-hexachloro-, SR-05000001837, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .delta.-, theta-Hexachlorocyclohexane, .delta.-(aeeee)-1,2,3,4,5,6-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .delta.-isomer, .beta.-Hexachlorocyclohexane, Lindane [USAN:INN:BAN], Kanodane, gamma&raquo, Fumite lindane, Scabene lotion, Detmol Extrakt, gamma-linda ne, H.C.H., Agrocide6G, Nexit Stark, 1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.-Hexachlorocyclohexane, .gamma.-Lindane, Lindane [USAN:USP:INN:BAN], Sang-&laquo, theta-BHC, Hexachlorzyklohexan, Gamma-BHC dust, Gamma-HCH dust, Nexol E, d-alpha-BHC, Sang-.gamma., alpha- BHC, eta-BHC, eta-HCH, 1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, Lindane,(S), alpha-hexacloran(e), BHC |A-isomer, .alpha.-Hexachloran, .gamma.-Hexachloran, .alpha.-HCH, .gamma.-HCH, BHC .alpha., BHCor HCH, HCH-.alpha., .alpha.-Hexachlorane, .gamma.-Hexachlorane, BHC-.alpha. isomer, BHC(.gamma.), G-BHC-.delta., HCH, technical grade, lindane (Gama-HCH), gamma-BHC (lindane), lindane (gamma-HCH), Lindane, 97%, Lindane (USP/INN), beta-Benzenehexachloride, Spectrum_001929, eta-Hexachlorocyclohexane, PS71_SUPELCO, zeta-Hexachlorocyclohexane, .gamma.-Benzohexachloride, .gamma.-Hexachlorobenzene, benzene-trans-hexachloride, DSSTox_CID_684, Hexachlorocyclohexane-Beta, Spectrum2_001864, Spectrum3_000860, Spectrum4_000700, Spectrum5_001586, 1,2,3,4,5,6-HCH, beta-Hexachlorocyclohexanes, DSSTox_CID_4134, Hexachlorocyclohexane-Alpha, beta-Hexac hlorocyclohexane, alpha-Hexachlorocyclohexanes, D0Q5IN, Gamma Benzene Hydrochloride, HCH (BHC) (technical), epsilon-Benzene hexachloride, gamma-:hexachlorocyclohexane, AC1L19VZ, .alpha.-Hexachlorcyclohexane, DSSTox_RID_75732, H.C.H, .alpha.-Benzene hexachloride, .gamma.-Benzene hexachloride, Benzene-1,2,3,4,5,6-hexachloride (Ambiguous), BIDD:PXR0097, DSSTox_GSID_20684, DSSTox_GSID_24134, SCHEMBL25895, SCHEMBL25896, SCHEMBL75689, .gamma.-Hexachlorocyclohexane, BSPBio_002479, KBioGR_001199, KBioSS_002471, SPECTRUM330071, 2-05-00-00011 (Beilstein Handbook Reference), 4-05-00-00056 (Beilstein Handbook Reference), 4-05-00-00058 (Beilstein Handbook Reference), 4-05-00-00060 (Beilstein Handbook Reference), 4-05-00-00061 (Beilstein Handbook Reference), MLS001333088, MLS001335969, MLS001335970, MLS001361319, beta-BHC, analytical standard, BIDD:ER0090, BIDD:ER0091, BIDD:ER0449, BIDD:ER0558, BIDD:GT0634, CHEMBL15891, DivK1c_000701, SCHEMBL140812, SCHEMBL140813, SCHEMBL472088, Benzene Hexachloride, .gamma., SPBio_001708, .epsilon.-Hexachlorocyclohexane, delta-BHC, analytical standard, gamma-BHC, analytical standard, CHEMBL389022, Hexachlorocyclohexane, Technical, SCHEMBL7647849, SCHEMBL8469477, SCHEMBL9120917, ZINC1621, CHEMBL1200921, CHEMBL1714528, CHEMBL1874247, CHEMBL2272381, Hexachlorocyclohexane (q-isomer), Hexachlorocyclohexane (z-isomer), Hexachlorocyclohexane [h-isomer], SCHEMBL10795898, HMS502D03, KBio1_000701, KBio2_002464, KBio2_005032, KBio2_007600, KBio3_001979, BHC (alpha-, beta-, gamma-), NSC7909, NSC8093, JLYXXMFPNIAWKQ-GPIVLXJGSA-N, JLYXXMFPNIAWKQ-LKPKBOIGSA-N, JLYXXMFPNIAWKQ-UHFFFAOYSA-N, NINDS_000701, HMS1923K17, HMS2091E05, HMS2230C24, HMS2231A06, HMS3369J21, Pharmakon1600-00330071, GAMMA-HEXACHLORO-CYCLOHEXANE, Benzene hexachloride-.alpha.-isomer, cpd with unspecified stereochemistry, HY-A0085, NSC-7909, NSC-8093, NSC11807, NSC11808, a-Hexachlorocyclohexane (HCH, BHC), Benzene Hexachloride (gamma-Isomer), Hexachlorocyclohexane,.gamma.-isomer, Tox21_111294, Tox21_200676, Tox21_201777, Tox21_202069, Tox21_202290, Tox21_300624, Tox21_300953, Tox21_302925, Tox21_303873, 7644AF, BDBM50410525, beta-HCH 100 microg/mL in Toluene, CCG-39862, LS-242, MFCD00135947, NSC-11807, NSC-11808, NSC755895, SBB061412, AKOS015903494, AKOS015914103, AKOS024390982, Cyclohexane,2,3,4,5,6-hexachloro-, HEXACHLOROCYCLOHEXANE (MIXTURE), ZINC100068484, ZINC100076865, ZINC100076868, ZINC100899052, ZINC245204924, ZINC263584078, beta-HCH 10 microg/mL in Cyclohexane, DB00431, FCH1320285, LS-7424, LS-7425, LS-7426, NSC-755895, (1alpha,2alpha,3alpha,4alpha,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, alpha-HCH 10 microg/mL in Cyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5alpha,6beta)-, delta-HCH 10 microg/mL in Cyclohexane, epsilon-HCH 100 microg/mL in Methanol, g-1,2,3,4,5,6-Hexachlorocyclohexane, gamma-HCH 10 microg/mL in Cyclohexane, IDI1_000701, (.+/-.)-.alpha.-Hexachlorocyclohexane, alpha-HCH 100 microg/mL in Cyclohexane, Cyclohexane,1,2,3,4,5,6-hexachloro-, delta-HCH 100 microg/mL in Cyclohexane, gamma-HCH 100 microg/mL in Cyclohexane, NCGC00094546-01, NCGC00094546-02, NCGC00094546-03, NCGC00094546-05, NCGC00094546-06, NCGC00094546-07, NCGC00094546-08, NCGC00094546-09, NCGC00094546-10, NCGC00094546-11, NCGC00159386-02, NCGC00159386-03, NCGC00159386-04, NCGC00159386-05, NCGC00163943-01, NCGC00163943-02, NCGC00163943-03, NCGC00163943-04, NCGC00163943-05, NCGC00248792-01, NCGC00254541-01, NCGC00254855-01, NCGC00256383-01, NCGC00258230-01, NCGC00259326-01, NCGC00259618-01, NCGC00259839-01, NCGC00357135-01, 6108-13-0, AC-11679, AN-41770, CAS-319-84-6, CAS-319-86-8, CC-02682, epsilon-HCH 10 microg/mL in Cyclohexane, LS-56881, epsilon-HCH 100 microg/mL in Cyclohexane, SBI-0051430.P003, .delta.,2,3,4,5,6-Hexachlorocyclohexane, KB-147807, Lindane, PESTANAL(R), analytical standard, LS-185311, LS-193399, LS-193400, LS-193401, .alpha.-1,2,3,4,5,6-Hexachlorcyclohexane, FT-0603490, FT-0606175, FT-0647466, ST51047431, V0158, WLN: L6TJ AG BG CG DG EG FG .delta., .alpha.-1,2,3,4,5,6-Hexachlorocyclohexane, .gamma.-1,2,3,4,5,6-Hexachlorocyclohexane, 1,2,3,4,5,6-.gamma.-Hexachlorocyclohexane, alpha-HCH, PESTANAL(R), analytical standard, beta-HCH, PESTANAL(R), analytical standard, delta-HCH, PESTANAL(R), analytical standard, C06988, C07075, C15214, C18738, D00360, 1,2,3,4,5,6-Hexachlorocyclohexane (.gamma.), 1,3,4,5,6-Hexachlorcyclohexane, .beta. isomer, AB00052031_02, Cyclohexane,2,3,4,5,6-hexachloro-, .delta.-, 1,2,3,4,5,6-hexachlorocyclohexane, alpha isomer, 1,3,4,5,6-Hexachlorocyclohexane, .gamma. isomer, 135764-EP2275422A1, 135764-EP2292608A1, alpha-1,2,3,4,5,6-Hexachlorocyclohexane, 99%, Benzene-1,2,3,4,5,6-hexachloride ((Ambiguous), C-18255, Cyclohexane, .alpha.-1,2,3,4,5,6-hexachloro-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-, .delta.-(aeeee)-1,3,4,5,6-Hexachlorocyclohexane, 1,2,3,4,5,6-Hexachlorocyclohexane (gamma-Isomer), 1|A,2|A,3|A,4|A,5|A,6|A-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .alpha.-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .beta.-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .gamma.-, HCH (BHC) (technical) 10 microg/mL in Isooctane, J-018587, J-018588, J-018589, LINDANE (BENZENE HEXACHLOROIDE-GAMMA ISOMER), SR-05000001837-1, SR-05000001837-4, Cyclohexane,2,3,4,5,6-hexachloro-, .delta.-isomer, I14-19248, I14-45278, alpha-HCH Solution, 100 mg/mL, (RM, ISO Guide 34), Cyclohexane, 1,2,3,4,5,6-hexachloro-, .alpha.-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta- (8CI), UNII-5477B350EK component JLYXXMFPNIAWKQ-CDRYSYESSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-GNIYUCBRSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-LKPKBOIGSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-SHFUYGGZSA-N, UNII-IVM9A2N49K component JLYXXMFPNIAWKQ-LKPKBOIGSA-N, UNII-IVM9A2N49K component JLYXXMFPNIAWKQ-SHFUYGGZSA-N, (1r,2c,3c,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2c,3t,4c,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2c,3t,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1R,2r,3S,4R,5s,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1s,2R,3R,4s,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, Lindane, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6, Lindane, Pharmaceutical Secondary Standard; Certified Reference Material, (1.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,3.beta.,4.alpha.,5.alpha.,6.beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3alpha,4alpha,5alpha,6alpha)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3alpha,4alpha,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5, 6-hexachlorocyclohexane, (1alpha,2alpha,3beta,4beta,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane, 1-.alpha.,2-.alpha.,3-.beta.,4-.alpha.,5-.beta.,6-.beta.-Hexachlorocyclohexane, beta-HCH solution, 100 mug/mL in methanol, PESTANAL(R), analytical standard, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5alpha,6alpha)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5beta,6beta)-, 1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.beta.,6.beta.)-, 20437-97-2, 25897-48-7, 39284-22-5, 53529-37-6, 60291-32-9, 8007-42-9, 8073-23-2, 89609-19-8, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.beta.,6.beta.)-, Cyclohexane,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, HCH, PESTANAL(R), analytical standard, mixture of isomers (alpha:beta:gamma:delta=1:1:1:1)


ID: 1086

chemical graph of compound 1086



InChIKey: JLZAERUVCODZQO-UGOWOXHDSA-N
SMILES: CC(=O)OC1CC[C@@]2(C3CC[C@@]4(C(CC[C@@]4(C3CC[C@@]2(C1)O)O)C5=CC(=O)OC5)C)C=O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"D Zhang" "Y Luo" "GW Carlile" "DY Thomas" "JW Hanrahan" "R Robert" "KA Teske"


CID is 44135347
synonyms found at PubChem are:
ACETYL STROPHANIDIN


ID: 1087

chemical graph of compound 1087



InChIKey: JMFRWRFFLBVWSI-NSCUHMNNSA-N
SMILES: COC1=C(C=CC(=C1)/C=C/CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 1549095
synonyms found at PubChem are:
CONIFERYL ALCOHOL, 458-35-5, Coniferol, Coniferylalcohol, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenol, gamma-Hydroxyisoeugenol, trans-Coniferyl alcohol, (E)-Coniferyl alcohol, 4-(3-Hydroxy-1-propenyl)-2-methoxyphenol, 3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol, 32811-40-8, 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenol, 4-Hydroxy-3-methoxycinnamic alcohol, 4-Hydroxy-3-methoxycinnamyl alcohol, Coniferylic alcohol, E-Coniferyl alcohol, UNII-E7SM92591P, CHEBI:17745, 4-[(1E)-3-Hydroxy-1-propenyl]-2-methoxyphenol, JMFRWRFFLBVWSI-NSCUHMNNSA-N, E7SM92591P, p-Hydroxy-m-methoxycinnamyl alcohol, 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-Hydroxy-3-methoxyphenyl)allyl alcohol, Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-, 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxyphenol, 4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenol, 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl), (E)-, 4-hydroxy-3-methoxy cinnamyl alcohol, 4-Hydroxy-3-methoxycinnamylic alcohol, 4-[3-Hydroxy-1-propenyl]-2-methoxyphenol, Coniferyl alcohol, E-, Coniferyl alcohol [MI], trans-coniferol, CONIFERYL-ALCOHOL, epsilon-coniferyl alcohol, AC1LU7QR, .gamma.-Hydroxyisoeugenol, Coniferyl alcohol, 98%, Phenol, 4-(3-hydroxy-1-propen-1-yl)-2-methoxy-, bmse000602, bmse010248, bmse010285, Epitope ID:116871, 4-(3-Hydroxy-1-propen-1-yl)-2-methoxyphenol, SCHEMBL177683, CHEMBL501870, DTXSID50186489, 4e70, JMFRWRFFLBVWSI-UHFFFAOYSA-N, MolPort-001-785-894, ZX-AT000357, 6307AB, MFCD00002922, ZINC12359045, AKOS005258118, FCH1115179, FCH4635646, OR24816, PS-4366, AJ-61355, AK122279, BBV-41802105, CC-25964, KB-76158, ST098738, AX8012054, DB-051336, KB-186780, RT-000096, 4-(3-hydroxy-1-propenyl)-2-methoxy-Phenol, ST24042895, 3-(4-Hydroxy-3-methoxyphenyl)prop-2-en-1-ol, C00590, (E)-4-(3-hydroxyprop-1-enyl)-2-methoxyphenol, 2-methoxy-4-[(E)-3-oxidanylprop-1-enyl]phenol, (E)-4-(3 -hydroxyprop-1-enyl)-2-methoxyphenol, 4-((1E)-3-hydroxyprop-1-enyl)-2-methoxyphenol, 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxy-phenol, A826901, (E) 3-(4-hydroxy-3-methoxyphenyl)-2-Propen-1-ol, I06-0311, Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-, (E)-, F8420572-6986-4EF3-917B-3298FD384F2C


ID: 1088

chemical graph of compound 1088



InChIKey: JMPKPWBLQUWFHQ-LUAGPVBASA-N
SMILES: C(C[N+](=O)[O-])C(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)OC(=O)CC[N+](=O)[O-])OC(=O)CC[N+](=O)[O-])OC(=O)CC[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6710740
synonyms found at PubChem are:
ENDECAPHYLLIN X, Spectrum2_000806, Spectrum3_001209, AC1O8K0A, BSPBio_002598, SPECTRUM211152, SPBio_000671, CHEMBL3039295, CHEBI:92961, KBio3_002098, CCG-39540, NCGC00178584-01, BRD-K54728231-001-02-3, beta-D-Glucopyranose 2,3,4,6-tetrakis(3-nitropropanoate), [(2R,3R,4S,5R,6R)-6-hydroxy-3,4,5-tris(3-nitropropanoyloxy)oxan-2-yl]methyl 3-nitropropanoate


ID: 1089

chemical graph of compound 1089



InChIKey: JMQMNWIBUCGUDO-WHFBIAKZSA-N
SMILES: C([C@@H](C(=O)O)N)SCSC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 68134
synonyms found at PubChem are:
Djenkolic acid, L-Djenkolic acid, 498-59-9, Djenkolate, L-Djenkolate, UNII-3QHC9R0YFZ, beta,beta'-Methylenedithiodialanine, L-Cysteine thioacetal of formaldehyde, 3,3'-(Methylenedithio)dialanine, S,S'-Methylenebiscysteine, 3QHC9R0YFZ, CHEBI:6211, 3,3'-Methylenedithiobis(2-aminopropanoic acid), Alanine, 3,3'-(methylenedithio)di-, Jengkolic acid, EINECS 207-863-4, NSC 76076, AC1Q5QNS, S,S'-methylenebis(cysteine), s,s'-methylenebis-l-cysteine, S,S'-Methylenedi-L-cysteine, SCHEMBL151396, AC1L293S, S,S'-methylene-bis-L-cysteine, CHEMBL3138615, C7H14N2SO42, CTK4J1781, BID1201, DTXSID80198075, ZX-AFC001017, ZINC1531043, 7783AF, AKOS030538008, API0003139, L-Cysteine, S,S'-methylenebis- (9CI), D0961, FT-0772324, C08275, Alanine, 3,3'-(methylenedithio)di-, L- (8CI), I14-61957, (2R,2'R)-3,3'-(methylenedisulfanediyl)bis(2-aminopropanoic acid), (2R,2'R)-3,3'-methylenebis(sulfanediyl)bis(2-aminopropanoic acid), (2R)-2-amino-3-[[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanylmethylsulfanyl]propanoic acid, CJ-24079


ID: 1090

chemical graph of compound 1090



InChIKey: JMTYYLMGSBSPPK-UHFFFAOYSA-N
SMILES: C1CCC(CC1)[Si](CCCN2CCCCC2)(C3=CC=C(C=C3)F)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957564
synonyms found at PubChem are:
p-Fluorohexahydro-sila-difenidol hydrochloride, P-F-HHSiD hydrochloride, Hexahydro-sila-difenidol hydrochloride, p-fluoro analog, EU-0100608, Hexahydro-Sila-Difenidol HCl, MLS002172447, CHEMBL1256647, Tox21_500608, CCG-221912, LP00608, NCGC00093983-01, NCGC00261293-01, SMR001254082, RT-014898, H-127, p-fluoro-hexahydro-sila-difenidol hydrochloride, SR-01000075319, J-003472, SR-01000075319-1, Cyclohexyl-(4-fluorophenyl)-(3-N-piperidinopropyl)silanol hydrochloride, p-Fluorohexahydro-sila-difenidol hydrochloride, powder, >=98% (HPLC), 175615-76-6, Hexahydro sila difenidol hydrochloride


ID: 1091

chemical graph of compound 1091



InChIKey: JMVIGOFRIJJUAW-HRFVKAFMSA-N
SMILES: C1[C@H](N[C@@H]1C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6604769
synonyms found at PubChem are:
trans-Azetidine-2,4-dicarboxylic acid, 161596-62-9, (2S,4S)-azetidine-2,4-dicarboxylic acid, (2S,4S)-(-)-Azetidine-2,4-dicarboxylic acid, tADA, (+/-)-trans-azetidine-2,4-dicarboxylic acid, Tocris-0860, AC1O7GUS, Lopac0_000099, CHEMBL43528, SCHEMBL179767, CTK0H6586, DTXSID80424982, ZINC2560277, AKOS022180335, CCG-204194, LP00099, NCGC00024830-01, NCGC00024830-02, NCGC00024830-03, NCGC00024830-04, NCGC00024830-05, AJ-40533, 2,4-Azetidinedicarboxylicacid, (2S,4S)-, RT-011094, A-244, CS-0056957, EU-0100099, (2S,4S)-Azetidine-2alpha,4beta-dicarboxylic acid, SR-01000075426, SR-01000597430, 2,4-Azetidinedicarboxylic acid, (2S,4S)- (9CI), J-009846, SR-01000075426-1, SR-01000597430-1


ID: 1092

chemical graph of compound 1092



InChIKey: JMVIGOFRIJJUAW-WSOKHJQSSA-N
SMILES: C1[C@@H](N[C@@H]1C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2733517
synonyms found at PubChem are:
cis-Azetidine-2,4-dicarboxylic acid, 121050-04-2, 2,4-Azetidinedicarboxylicacid, (2R,4S)-rel-, Biomol-NT_000214, AC1MBZ33, Lopac0_000089, CHEMBL41680, BPBio1_001300, SCHEMBL1321720, CTK4B2155, JMVIGOFRIJJUAW-WSOKHJQSSA-N, ZINC2567368, cis azetidine-2,4-dicarboxylic acid, AKOS006358662, CCG-204184, LP00089, NCGC00093592-01, NCGC00093592-02, NCGC00093592-03, NCGC00093592-04, (4S,2R)azetidine-2,4-dicarboxylic acid, (2R,4S)-azetidine-2,4-dicarboxylic acid, (2S,4R)-azetidine-2,4-dicarboxylic acid, A-243, EU-0100089, FT-0604657, FT-0604675, ST50823958, 2,4-Azetidinedicarboxylicacid,(2R,4S)-rel-, (2R,4S)-Azetidine-2beta,4beta-dicarboxylic acid, SR-01000075425, SR-01000075425-1, 2,4-Azetidinedicarboxylic acid, (2R,4S)-rel- (9CI)


ID: 1093

chemical graph of compound 1093



InChIKey: JNELGWHKGNBSMD-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 7020
synonyms found at PubChem are:
XANTHONE, 9H-Xanthen-9-one, 90-47-1, Xanthen-9-one, 9-Xanthenone, Benzophenone oxide, 9-Oxoxanthene, Genicide, Xanthenone, 9-Xanthone, Diphenylene ketone oxide, Dibenzo-gamma-pyrone, Xanthene, 9-oxo-, 9H-Xanthene, 9-oxo-, Caswell No. 905, UNII-9749WEV0CA, NSC 14978, Dibenzo-.gamma.-pyrone, diphenyline ketone oxide, EINECS 201-997-7, EPA Pesticide Chemical Code 086503, AI3-00077, 9749WEV0CA, CHEMBL186784, E 6, CHEBI:37647, JNELGWHKGNBSMD-UHFFFAOYSA-N, NSC14978, ST024714, 9-oxo-xanthene, xanthene-9-one, Xanthone (Genicide), Xanthone, 97%, AC1L1NTM, Spectrum2_000052, Spectrum3_001884, DSSTox_CID_1795, ACMC-209r6d, Xanthone, 99% 25g, DSSTox_RID_76331, DSSTox_GSID_21795, SCHEMBL41161, BSPBio_003388, SPECTRUM200523, KSC486O8J, MLS002207109, SPBio_000203, ghl.PD_Mitscher_leg0.1212, DTXSID6021795, CTK3I6784, KBio3_002891, KS-00000UQW, WLN: T C666 BO IVJ, MolPort-001-759-220, HMS3651G22, BCP21155, STR05546, ZINC3860823, Tox21_301151, ANW-39491, BDBM50155411, CCG-38356, NSC-14978, s2372, SBB069491, STK372481, AKOS001213782, MCULE-8122570588, NE10375, RP25438, RTR-028437, SDCCGMLS-0066462.P001, TRA0014485, CAS-90-47-1, NCGC00095484-01, NCGC00095484-02, NCGC00095484-03, NCGC00255049-01, AN-42523, R895, SC-75486, SMR000112239, LS-162426, TR-028437, FT-0645039, A843557, AC-907/21098006, SR-05000002437, S14-0934, SR-05000002437-1, W-100331, F8889-9282, Xanthone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8, N-methyl-1-[5-({[(4-methylbenzyl)amino]carbonyl}amino)pyridin-2-yl]piperidine-4-carboxamide


ID: 1094

chemical graph of compound 1094



InChIKey: JNENSSREQFBZGT-UHFFFAOYSA-N
SMILES: C1CN=C2C3=CC=CC=C3SC(=N)N2C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6603967
synonyms found at PubChem are:
PD 404,182, PD-404182, 72596-74-8, UNII-3PYK7K517E, 3PYK7K517E, 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine, 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine, 6H-6-Imino-(2,3,4,5-tetrahydropyrimido)[1,2-c]-[1,3]benzothiazine, NCGC00015809-01, Lopac-P-2742, AC1O7G5X, Lopac0_000947, CHEMBL595227, SCHEMBL4097420, AOB5965, DTXSID00424969, JNENSSREQFBZGT-UHFFFAOYSA-N, MolPort-003-959-210, ZINC3993826, 2H,6H-Pyrimido(1,2-C)(1,3)benzothiazin-6-imine, 3,4-dihydro-, AKOS025293487, CCG-205028, NCGC00015809-02, NCGC00015809-03, NCGC00094251-01, NCGC00094251-02, PD 404182, EU-0100947, P 2742, PD 404,182, >=98% (HPLC), SR-01000076065, SR-01000076065-1, BRD-K14798637-001-01-7


ID: 1095

chemical graph of compound 1095



InChIKey: JNMRHUJNCSQMMB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NC=CS2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5340
synonyms found at PubChem are:
sulfathiazole, 72-14-0, Sulphathiazole, Sulfathiazol, Sulfanilamidothiazole, 2-Sulfanilamidothiazole, Norsulfazole, 2-Sulfonamidothiazole, Norsulfasol, Thiazamide, Neostrepsan, Sulfocerol, Thiozamide, 2-Sulfanilamidothiazol, Sulzol, 2-(Sulfanilylamino)thiazole, Azoquimiol, Azoseptale, Norsulfazol, Poliseptil, Sanotiazol, Sulfathiazolum, Sulfatiazol, Thiacoccine, Thiasulfol, Wintrazole, Cerazole, Chemosept, Cibazol, Eleudron, Estafilol, Planomide, Septozol, Duatok, Dulana, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide, Coco-Thiazole, 2-(p-Aminobenzenesulfonamido)thiazole, Formosulfathiazole, Streptosilthiazole, N(1)-2-Thiazolylsulfanilamide, Sulfamul, Usaf sn-9, Cerazol (suspension), 2-(p-Aminobenzenesulphonamido)thiazole, 4-Amino-N-2-thiazolylbenzenesulfonamide, Norsulfazolum, Ciba 3714, Benzenesulfonamide, 4-amino-N-2-thiazolyl-, Solfatiazolo [DCIT], Caswell No. 809B, 4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide, M&B 760, RP 2090, UNII-Y7FKS2XWQH, 4-Amino-N-thiazol-2-yl-benzenesulfonamide, 2090 R.P., Sulfathiazol [INN-French], Sulfatiazol [INN-Spanish], N1-2-Thiazolylsulfanilamide, Sulfathiazolum [INN-Latin], CCRIS 765, M+B 760, CHEBI:9337, N1-(2-Thiazolyl)sulfanilamide, 2090 rp, 2-Sulfanilamidothiazol [German], Sulfanilamide, N1-2-thiazolyl-, 4-Amino-N-(1,3-Thiazol-2-Yl)Benzene-1-Sulfonamide, HSDB 4380, N(sup 1)-2-Thiazolylsulfanilamide, Y7FKS2XWQH, Sulfanilamide, N(1)-2-thiazolyl-, EINECS 200-771-5, NSC 31812, 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CHEMBL437, EPA Pesticide Chemical Code 077903, NSC 683531, Sulfanilamide, N(sup 1)-2-thiazolyl-, 4-Amino-N-2-thiazolyl-benzenesulfonamide, AI3-01050, N'-(2-Thiazolyl)sulfanilamide, JNMRHUJNCSQMMB-UHFFFAOYSA-N, N(sup1)-(2-Thiazolyl)sulfanilamide, NSC683531, Sulfanilamide, N(sup1)-2-thiazolyl-, CAS-72-14-0, NCGC00016309-02, NCGC00016309-06, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, DSSTox_CID_6068, DSSTox_RID_78004, DSSTox_GSID_26068, [(4-Aminophenyl)sulfonyl]-1,3-thiazol-2-ylamine, Solfatiazolo, SR-05000001722, Sulfathiazole [USAN:INN], sulfthiazole, Enterobiocine, Sulfavitina, Cerazol, Neo-Strepsan, Sulfathiazole [USP:INN:BAN], 2-Sulfathiazole, Sulfathiazole(ST), YTZ, Prestwick_430, Spectrum_001000, Prestwick0_000016, Prestwick1_000016, Prestwick2_000016, Prestwick3_000016, Spectrum2_000841, Spectrum3_001729, Spectrum4_000348, Spectrum5_001441, Sulfathiazole (USP/INN), N-2-Thiazolylsulfanilamide, Epitope ID:122234, AC1L1K4W, AC1Q51XN, Cambridge id 5251400, cid_5340, Oprea1_105970, Oprea1_297844, SCHEMBL94165, BSPBio_000051, BSPBio_003378, KBioGR_000755, KBioSS_001480, KSC917Q1B, MLS002154174, N-1-2-Thiazolylsulfanilamide, DivK1c_000560, SPECTRUM1500553, SPBio_000821, SPBio_001972, ARONIS018158, BPBio1_000057, WLN: T5N CSJ BMSWR DZ, DTXSID8026068, CTK8B7810, HMS501L22, KBio1_000560, KBio2_001480, KBio2_004048, KBio2_006616, KBio3_002598, KS-00004AEL, MolPort-000-488-590, N(sup1)-2-Thiazolylsulfanilamide, NINDS_000560, HMS1568C13, HMS1921C07, HMS2092K09, HMS2095C13, HMS2259A13, HMS3652A03, HMS3712C13, Pharmakon1600-01500553, ZINC121458, HY-B0507, KS-00000H3L, NSC31812, SULFATHIAZOLE (TRIPLE SULFA), Tox21_110363, Tox21_202243, Tox21_303238, ANW-58669, BDBM50027796, CCG-40296, MFCD00005319, NSC-31812, NSC757331, s3116, SBB000946, STK043870, 2-(4-Aminobenzenesulfonamido)thiazole, AKOS000108630, Tox21_110363_1, 144-74-1 (mono-hydrochloride salt), CS-2708, DB06147, LS-1612, MCULE-1370710137, NE10395, NSC-683531, NSC-757331, RTR-023622, SDCCGMLS-0065585.P001, IDI1_000560, NCGC00016309-01, NCGC00016309-03, NCGC00016309-04, NCGC00016309-05, NCGC00016309-07, NCGC00016309-08, NCGC00016309-09, NCGC00016309-10, NCGC00016309-14, NCGC00091133-01, NCGC00091133-02, NCGC00091133-03, NCGC00091133-04, NCGC00257187-01, NCGC00259792-01, Sulfanilamide, N1-2-thiazolyl- (8CI), 2090 R.P, AC-12783, AJ-11762, AN-23809, BAS 00836087, DS-17245, K225, KB-97591, NCI60_002730, SC-77388, SMR000017368, ST011910, ZB004177, 4-Amino-N-(thiazol-2-yl)benzenesulfomide, SBI-0051527.P004, Sulfanilamide, N1-4-thiazolin-2-ylidene-, KB-224306, TR-023622, 4-amino-N-(thiazol-2-yl)-benzenesulfonamide, AB00052102, BB 0245015, FT-0631310, S0272, ST24028888, Sulfathiazole 100 microg/mL in Acetonitrile, 4-[(1,3-Thiazol-2-yl)aminosulfonyl]aniline, Sulfathiazole, analytical standard, >=98.0%, 9610-EP2295053A1, 9610-EP2308872A1, 9610-EP2316829A1, C11169, D01047, AB00052102_14, AB00052102_15, Sulfathiazole, VETRANAL(TM), analytical standard, 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide #, I06-0506, Q-201765, SR-05000001722-1, SR-05000001722-3, Sulfathiazole, Antibiotic for Culture Media Use Only, BRD-K14705039-001-05-7, BRD-K14705039-001-08-1, I14-38050, F1443-4816, Sulfathiazole, European Pharmacopoeia (EP) Reference Standard, Sulfathiazole, United States Pharmacopeia (USP) Reference Standard, 72-14-0,6052-33-1,158269-46-6,144-74-1(sodiumsalt), 158269-46-6, 6052-33-1, 859037-27-7


ID: 1096

chemical graph of compound 1096



InChIKey: JNNGEAWILNVFFD-CDJYTOATSA-N
SMILES: C[C@H]1[C@H](C[C@H]2[C@@H]1[C@@H](OC=C2C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 89640
synonyms found at PubChem are:
Loganic acid, 22255-40-9, Loganate, CHEBI:30632, (1S,4aS,6S,7R,7aS)-1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, Loganic-acid, EINECS 244-875-9, C16H24O10, Spectrum_001509, SpecPlus_000543, AC1L3IAO, Spectrum2_001971, Spectrum3_001930, Spectrum4_001690, Spectrum5_000340, BSPBio_003530, KBioGR_001960, KBioSS_001989, DivK1c_006639, SCHEMBL308008, SPECTRUM1504071, SPBio_002121, CHEMBL1081585, KBio1_001583, KBio2_001989, KBio2_004557, KBio2_007125, KBio3_002760, MolPort-003-665-719, ZINC3978795, CCG-39437, MFCD00017417, AKOS032962058, MCULE-6569288361, SDCCGMLS-0066805.P001, Loganic acid, >=95% (LC/MS-ELSD), NCGC00178007-01, NCGC00178007-02, CC-30020, N2320, W1725, C01512, 255L409, C-21260, W-107488, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha))-1-(beta-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta(c)pyran-4-carboxylic acid, Cyclopenta[c]pyran-4-carboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-,(1S,4aS,6S,7R,7aS)-, EQV


ID: 1097

chemical graph of compound 1097



InChIKey: JOAHPSVPXZTVEP-QGPMSJSTSA-N
SMILES: CCN(CC)C(=O)N[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957722
synonyms found at PubChem are:
R(+)-Terguride, NCGC00094476-03, Biomol-NT_000081, Lopac0_001234, BPBio1_001406, CHEMBL1480516, CHEBI:92105, CCG-205308, NCGC00094476-01, NCGC00094476-02, EU-0101234, T-165, N-(6-Methylergolin-8beta-yl)-N',N'-diethylurea, SR-01000076220, SR-01000076220-1, BRD-K05901394-001-01-1, R(+)-N,N-Diethyl-N'[(8alpha)-6-methylergolin-8-yl]urea, 88293-83-8


ID: 1098

chemical graph of compound 1098



InChIKey: JOHZPMXAZQZXHR-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4831
synonyms found at PubChem are:
pipemidic acid, 51940-44-4, Deblaston, Pipram, Palin, Acido pipemidico, Acide pipemidique, Acidum pipemidicum, Pipedac, Pipemid, Uromidin, Dolcol, UNII-LT12J5HVR8, Acido pipemidico [Spanish], 1489 RB, RB 1489, Acide pipemidique [INN-French], Acido pipemidico [INN-Spanish], Acidum pipemidicum [INN-Latin], 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid, EINECS 257-530-2, BRN 0626575, LT12J5HVR8, 5,8-Dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid, MLS000028608, CHEBI:75250, piperamic acid, C14H17N5O3, Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, NCGC00016866-01, SMR000058711, CAS-51940-44-4, DSSTox_CID_3479, P-6835, Acide ethyl-8 oxo-5 piperazinyl-2 dihydro-5,8 pyrido(2,3-d)pyrimidine-6 carboxylique [French], DSSTox_RID_77045, DSSTox_GSID_23479, 8-ethyl-5-oxo-2-piperazin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic Acid, 8-ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazinyl-8-hydropyridino[2,3-d]pyrimidine-6-carboxylic acid, Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)-, Pyrido[2,3-d]pyrimidine-6-carboxylicacid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, SR-01000000245, Pipemidic acid [INN:DCF], pipeacid, uropimid, Pipemidicacid, Pipemidic, CCRIS 8517, Pipemidic acid [INN:BAN:DCF], Nuril (TN), Pipemidic Acid,(S), Pipemidic acid hydrate, Pipemidic acid (INN), Spectrum_001387, Opera_ID_1142, Prestwick0_000897, Prestwick1_000897, Prestwick2_000897, Prestwick3_000897, Spectrum2_001185, Spectrum3_001487, Spectrum4_000155, Spectrum5_001214, AC1L1J1W, AC1Q5RD4, BSPBio_000714, BSPBio_003073, KBioGR_000630, KBioSS_001867, BIDD:GT0126, CHEMBL30116, DivK1c_000651, SCHEMBL135557, SPECTRUM1502024, SPBio_001229, SPBio_002923, AC1Q310B, BPBio1_000786, DTXSID3023479, CTK1G9533, HMS502A13, KBio1_000651, KBio2_001867, KBio2_004435, KBio2_007003, KBio3_002573, ZINC57466, JOHZPMXAZQZXHR-UHFFFAOYSA-N, MolPort-001-839-001, NINDS_000651, HMS1570D16, HMS1921F04, HMS2097D16, HMS3714D16, Pharmakon1600-01502024, BCP13633, HY-B1210, KS-00001FB6, Tox21_110655, MFCD00057291, NSC758160, SBB012523, STK686262, AKOS005599752, Tox21_110655_1, API0003860, CCG-220897, CS-4838, MCULE-8992370691, NSC-758160, Acide ethyl-8 oxo-5 piperazinyl-2 dihydro-5,8 pyrido(2,3-d)pyrimidine-6 carboxylique, IDI1_000651, SMP1_000242, NCGC00016866-02, NCGC00016866-03, NCGC00016866-04, NCGC00016866-05, NCGC00016866-06, NCGC00016866-07, NCGC00016866-08, NCGC00016866-11, NCGC00023999-03, NCGC00023999-04, NCGC00178314-01, NCGC00178314-02, AN-41083, AS-47690, ST072200, SBI-0051703.P002, LS-134084, AB00490004, V0168, A-7387, D08379, AB00052258_14, A828860, SR-01000000245-2, SR-01000000245-3, SR-01000000245-4, BRD-K08999871-001-05-5, BRD-K08999871-001-13-9, Pipemidic acid, Antibiotic for Culture Media Use Only, A3830/0162685, 8-ethyl-5-oxo-2-(1-piperazinyl)-6-pyrido[2,3-d]pyrimidinecarboxylic acid, 2-(1-piperazinyl)-5,8-dihydro-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 2-(1-piperazinyl)-8-ethyl-5,8-dihydro-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 5,8-Dihydro-8-ethyl-2-(1-piperazinyl)-5-oxopyrido-[2,3-d]pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-2-(1-piperazinyl)-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 7-(1-Piperazinyl)-1-ethyl-4-oxo-1,4-dihydro-6,8-diazaquinoline-3-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2- [1-piperazinyl]pyrido[2,3-d]- pyrimidine-6-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2-[1-piperazinyl]pyrido[2,3-d]-pyrimidine-6-carboxylic acid, 8-ethyl-5-oxidanylidene-2-piperazin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 108911-86-0, AC1OCK1X, 8-ethyl-5-oxo-2-piperazin-4-ium-1-ylpyrido[2,3-d]pyrimidine-6-carboxylate


ID: 1099

chemical graph of compound 1099



InChIKey: JOJPJLHRMGPDPV-LZQROVCBSA-N
SMILES: C1CC1CN2CC[C@]34[C@@H]5C6=C(C[C@]3([C@H]2CC7=C4C(=C(C=C7)O)O5)O)C8=C(N6)[C@H]9[C@@]12CCN([C@@H]([C@@]1(C8)O)CC1=C2C(=C(C=C1)O)O9)CC1CC1.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957626
synonyms found at PubChem are:
nor-Binaltorphimine dihydrochloride, Nor-bni, nor-BNI dihydrochloride, Norbinaltorphimine dihydrochloride, 105618-26-6, 113158-34-2, 4,8:11,15-Dimethano-20H-bisbenzofuro[2,3-a:3',2'-i]dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol,7,12-bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-,(4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)-, EU-0100806, D0K9HE, CHEMBL2374078, MolPort-003-958-934, Tox21_500806, MFCD00069374, AKOS024457633, LP00806, NCGC00094139-01, NCGC00261491-01, nor-Binaltorphimine dihydrochloride, solid, HY-100903, CS-0020573, N 1771, SR-01000075482, SR-01000597959, J-001459, SR-01000075482-1, SR-01000597959-1, 17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino- 7,7'-binorphinan-3,4',14,14'-tetrol dihydrochloride


ID: 1100

chemical graph of compound 1100



InChIKey: JOWUQCJWCRNVMQ-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957705
synonyms found at PubChem are:
SDZ-205,557 hydrochloride, SDZ 205-557 hydrochloride, 137196-67-9, SDZ-205 557 HCL, 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride, 1197334-02-3, JOWUQCJWCRNVMQ-UHFFFAOYSA-N, 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(diethylamino)ethyl ester hydrochloride, EU-0101153, MLS002153305, CHEMBL1256773, MolPort-003-959-508, Tox21_501153, SDZ-205,557 hydrochloride, solid, AKOS024456921, CCG-222457, LP01153, NCGC00015916-02, NCGC00092301-01, NCGC00094416-01, NCGC00261838-01, BC600837, SMR001230722, S-174, SR-01000075581, J-006976, SR-01000075581-1, 1197334-02-3 (SDZ 205557 Hydrochloride), 137196-67-9(SDZ 205557), 2-(DIETHYLAMINO)ETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE, 2-methoxy-4-amino-5-chloro-benzoic acid 2-(diethylamino)-ethyl ester hydrochloride


ID: 1101

chemical graph of compound 1101



InChIKey: JOYRKODLDBILNP-UHFFFAOYSA-N
SMILES: CCOC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5641
synonyms found at PubChem are:
urethane, ETHYL CARBAMATE, 51-79-6, Urethan, Ethylurethane, Ethyl urethane, Carbamic acid, ethyl ester, Carbamic acid ethyl ester, Ethylcarbamate, Pracarbamine, Leucethane, Pracarbamin, Ethyl urethan, Aethylcarbamat, Aethylurethan, O-Ethylurethane, U-Compound, Ethylurethan, Leucothane, Estane 5703, Uretan etylowy, Uretan, Uretano [DCIT], Carbamidsaeure-aethylester, Urethanum, NSC 746, Aethylurethan [German], Aethylcarbamat [German], Ethylester kyseliny karbaminove, ethyl aminoformate, O-Ethyl urethane, Urethanum [INN-Latin], Uretan etylowy [Polish], RCRA waste number U238, Ethyl ester of carbamic acid, X 41, Carbamidsaeure-aethylester [German], o-Ethyl carbamate, Urethane [INN:BAN:DCF], C3H7NO2, CCRIS 619, UNII-3IN71E75Z5, Ethylester kyseliny karbaminove [Czech], A 11032, HSDB 2555, EINECS 200-123-1, NH2COOC2H5, RCRA waste no. U238, AI3-00553, NSC746, CHEBI:17967, Urethane + ethanol (combination), JOYRKODLDBILNP-UHFFFAOYSA-N, 3IN71E75Z5, Aethylurethan (german), NCGC00095041-01, Aethylcarbamat (german), DSSTox_CID_1427, DSSTox_RID_76156, DSSTox_GSID_21427, Uretano, Carbamate, Ethyl, CAS-51-79-6, Urethane [INN:DCF], SR-05000001854, Ethyl carbamate homopolymer, Urethane, INN, Carbamic acid, ethyl ester, homopolymer, Spectrum_001685, Urethane, >=99%, AC1L1KSZ, Spectrum2_000909, Spectrum3_000965, Spectrum4_001082, Spectrum5_001651, ACMC-209kw3, WLN: ZVO2, BSPBio_002569, KBioGR_001464, KBioSS_002165, Urethane, analytical standard, KSC269I5R, ARONIS27009, BIDD:ER0508, DivK1c_000060, SPECTRUM1503304, SPBio_000758, CHEMBL462547, DTXSID9021427, CTK1G9458, HMS500C22, KBio1_000060, KBio2_002165, KBio2_004733, KBio2_007301, KBio3_001789, NSC-746, MolPort-001-785-624, NINDS_000060, Urethane, >=99.0% (GC), HMS1922A10, HMS2093C21, Pharmakon1600-01503304, ZINC901020, HY-B1207, KS-00000H8Z, KS-000048ID, Tox21_111398, Tox21_201761, Tox21_300494, ANW-31345, CCG-39905, MFCD00007966, NSC758452, s4544, STL257390, AKOS000118772, Tox21_111398_1, AN-4992, CS-4731, DB04827, LS-1317, MCULE-1776877276, NSC-758452, RP18512, RTC-061437, TRA0096154, IDI1_000060, NCGC00095041-02, NCGC00095041-03, NCGC00095041-04, NCGC00095041-05, NCGC00095041-06, NCGC00095041-08, NCGC00254522-01, NCGC00259310-01, 26680-22-8, AJ-24326, CJ-04522, KB-51529, SC-16133, ZB015235, SBI-0051812.P002, SBI-0051812.P003, AB1009252, ST2413069, TC-061437, AM20100253, FT-0626365, 6533-EP1441224A2, 6533-EP2270113A1, 6533-EP2270114A1, 6533-EP2272517A1, 6533-EP2272935A1, 6533-EP2274983A1, 6533-EP2275418A1, 6533-EP2277565A2, 6533-EP2277566A2, 6533-EP2277567A1, 6533-EP2277568A2, 6533-EP2277569A2, 6533-EP2277570A2, 6533-EP2277880A1, 6533-EP2280006A1, 6533-EP2281813A1, 6533-EP2287160A1, 6533-EP2287165A2, 6533-EP2287166A2, 6533-EP2289483A1, 6533-EP2292280A1, 6533-EP2292593A2, 6533-EP2292610A1, 6533-EP2292620A2, 6533-EP2295399A2, 6533-EP2295438A1, 6533-EP2298312A1, 6533-EP2298758A1, 6533-EP2298759A1, 6533-EP2298767A1, 6533-EP2298783A1, 6533-EP2299326A1, 6533-EP2302003A1, 6533-EP2302382A2, 6533-EP2302383A2, 6533-EP2305250A1, 6533-EP2305648A1, 6533-EP2305664A1, 6533-EP2305808A1, 6533-EP2308510A1, 6533-EP2309584A1, 6533-EP2314587A1, 6533-EP2316470A2, 6533-EP2377847A1, C01537, K-9500, AB00052344_04, I14-6090, SR-05000001854-1, SR-05000001854-2, BRD-K24297741-001-01-1, Carbamic acid ethyl ester;Ethyl carbamate;Ethylurethane, Z33546369, Carbamic acid ethyl ester; Ethyl carbamate; Ethylurethane, F0001-1333, InChI=1/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5, 121382-27-2


ID: 1102

chemical graph of compound 1102



InChIKey: JPMYFOBNRRGFNO-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5281617
synonyms found at PubChem are:
Genkwanin, 437-64-9, Gengkwanin, 4',5-Dihydroxy-7-methoxyflavone, 5,4'-Dihydroxy-7-methoxyflavone, 7-O-Methylapigenin, 7-Methylapigenin, Apigenin 7-methyl ether, Puddumetin, Gonkwanin, UNII-5K3I5D6B2B, 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, 5K3I5D6B2B, CHEMBL210635, CHEBI:75718, 4'',5-dihydroxy-7-methoxyflavone, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one, 4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, 7-Methoxyapigenin, Henquanin, 7'O-methyl-apigenin, ACMC-20amrz, AC1NQYQP, Apigenin-7-methylether, Spectrum_000330, apigenin-7-methyl ether, SpecPlus_000835, Spectrum2_001355, Spectrum3_001401, Spectrum4_001667, Spectrum5_000573, Apigenin 7-O-Methyl Ether, BSPBio_003042, KBioGR_002193, KBioSS_000810, DivK1c_006931, Genkwanin, analytical standard, SCHEMBL866123, SPBio_001569, 4,5-Dihydroxy-7-methoxyflavone, Genkwanin, >=98% (HPLC), CTK4I7720, KBio1_001875, KBio2_000810, KBio2_003378, KBio2_005946, KBio3_002262, DTXSID80195908, JPMYFOBNRRGFNO-UHFFFAOYSA-N, MolPort-003-665-822, 4',5-dihydroxy-7-methoxy flavone, HY-N0731, ZINC5732375, 4'',5-dihydroxy-7-methoxy flavone, BDBM50187658, CCG-38838, LMPK12111018, AKOS015896775, Flavone, 4',5-dihydroxy-7-methoxy-, MCULE-4718928065, NCGC00178332-01, 4CN-1073, ST057642, DB-051163, TC-169190, CS-0009744, FT-0617186, N2092, W1623, 4',5-Dihydroxy-7-methoxyflavone, AldrichCPR, C10046, C-57765, I07-0230, BRD-K29160894-001-02-9, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-chromen-4-one, 5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chromen-4-one, 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one #


ID: 1103

chemical graph of compound 1103



InChIKey: JQJSTVUROJELSR-UHFFFAOYSA-H
SMILES: N.N.N.N.N.N.N.N.N.N.N.N.N.N.O.O.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru+2].[Ru+2].[Ru+2]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 16218584
synonyms found at PubChem are:
MFCD00011479, SR-01000076250, 6Cl.O2Ru3.14NH3, Ruthenium Red, Technical grade, degrees +/->> AENo>> iE, MolPort-003-939-248, 5423AF, AKOS024456597, Azane;ruthenium(2+);hexachloride;dihydrate, J-002508, SR-01000076250-2, SR-01000076250-3, Ruthenium Red, for microscopy, >=85% (calc. on dry substance, AT), Ruthenium Red, for microscopy, 85.0-115.0% (calc. on dry basis, AT), triruthenoxane-1,1,3,3,5,5-hexakis(ylium) tetradecaamine hexachloride, CHEBI:34956, [{Ru(NH3)5}(mu-O){Ru(NH3)4}(mu-O){Ru(NH3)5}]Cl6, tetradecaammine-1kappa(5)N,2kappa(5)N,3kappa(4)N-di-mu-oxidotriruthenium hexachloride


ID: 1104

chemical graph of compound 1104



InChIKey: JQPDCKOQOOQUSC-OOZYFLPDSA-N
SMILES: CC(C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 107883
synonyms found at PubChem are:
Dihydrokainic acid, Dihydrokainate, 52497-36-6, Dihydrokainic Acid, Natural, CHEMBL279561, CHEBI:43562, (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid, (3S,4R)-3-(carboxymethyl)-4-(propan-2-yl)-L-proline, (2S,3S,4R)-2-carboxy-4-(1-methylethyl)-3-pyrrolidineacetic acid, (2S,3S,4R)-3-(carboxymethyl)-4-(propan-2-yl)pyrrolidine-2-carboxylic acid, 1ftk, 1xhy, Dihydrokaioic Acid, (3s,4r)-3-(carboxymethyl)-4-isopropyl-l-proline, 2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid, AC1L32XE, AC1Q5R4V, SCHEMBL155919, CTK1H2670, DTXSID20200489, MolPort-003-940-944, HMS3261K11, ZINC3995564, Tox21_500375, BDBM50240399, BN0188, PDSP2_001490, AKOS024456387, CCG-221679, LP00375, VZ31869, NCGC00261060-01, CC-26819, B6208, Dihydrokainic acid, >=98% (HPLC), powder, A829114, C-11499, SR-01000597697, SR-01000597697-1, (3S,4S)-3-(carboxymethyl)-4-(1-methylethenyl)-L-proline, 3-carboxymethyl-4-isopropyl-pyrrolidine-2-carboxylic acid, (2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidinium-2-carboxylate, (2S,3S,4R)-3-(carboxymethyl)-4-isopropylpyrrolidine-2-carboxylic acid, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-yl-2-pyrrolidinecarboxylic acid, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-ylpyrrolidine-2-carboxylic acid, (2S,3S,4R)-4-isopropyl-3-(2-oxido-2-oxoethyl)pyrrolidinium-2-carboxylate, 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethyl)-, (2S,3S,4R)-, 3-Pyrrolidineaceticacid, 2-carboxy-4-(1-methylethyl)-, (2S,3S,4R)-, (2S,3S,4R)-3-(2-hydroxy-2-oxoethyl)-4-propan-2-yl-pyrrolidine-2-carboxylic acid, (2S-(2alpha,3beta,4beta))-2-Carboxy-4-(1-methylethyl)-3-pyrrolidineacetic acid


ID: 1105

chemical graph of compound 1105



InChIKey: JRFKIOFLCXKVOT-UHFFFAOYSA-N
SMILES: C1=CC(=CN=C1)C(=O)NCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 77116
synonyms found at PubChem are:
N-(Hydroxymethyl)nicotinamide, 3569-99-1, Nikomethamide, Bilamid, n-hydroxymethylnicotinamide, Bilizorin, Bilocid, Cholamid, Cholamide, Nicodin, Nicodine, Nicoform, Nikodin, Nikoform, Coloton, Felosan, Isochol, Bidbilan, Savatin, Nicometamide, Biloide, Biobilan, Hydroxymethylnicotinamide, N-(hydroxymethyl)pyridine-3-carboxamide, Nicotinamide, N-(hydroxymethyl)-, 3-Pyridinecarboxamide, N-(hydroxymethyl)-, 3-Pyridinecarboxylic acid hydroxymethylamide, Cholamide (pyridine deriv.), Nicotinsaeurehydroxymethylamid, Nicotinylmethylamide, UNII-1N1YGM997E, N-(Hydroxymethyl)-3-pyridinecarboxamide, EINECS 222-668-4, C 1094, N-Hydroxymethyl-nicotinamide, BRN 0128633, N-(hydroxymethyl)-nicotinamide, 1N1YGM997E, JRFKIOFLCXKVOT-UHFFFAOYSA-N, 3-Pyridinecarboxylic acid N-hydroxymethylamide, Nifoform, Cholamid (TN), Nikoform (TN), Spectrum_000376, ACMC-209iip, SpecPlus_000641, Nicotinylmethylamide,(S), AC1L2SDR, AC1Q7DCY, Spectrum2_001197, Spectrum3_001014, Spectrum4_001142, Spectrum5_001885, Oprea1_521547, Oprea1_687785, BSPBio_002767, KBioGR_001683, KBioSS_000856, MLS002695904, CHEMBL92024, DivK1c_006737, SCHEMBL352358, SPECTRUM2300137, SPBio_001273, Jsp006415, CTK3J3158, JRFKIOFLCXKVOT-UHFFFAOYSA-, KBio1_001681, KBio2_000856, KBio2_003424, KBio2_005992, KBio3_001987, DTXSID20189205, CHEBI:134775, MolPort-001-572-850, ZINC409246, ALBB-023192, KS-000012GY, N-(Hydroxymethyl)nicotinamide, 98%, ANW-28271, CCG-40316, AKOS000121436, AC-6974, AN-9462, MCULE-5606088997, N-(hydroxymethyl)-3-pyridylcarboxamide, VZ33319, NCGC00095786-01, NCGC00095786-02, AJ-22696, LS-96436, M707, SMR001562101, ZB013891, RT-001295, A6230, FT-0629289, R1217, ST24031347, ST45016703, D08051, W-106656, InChI=1/C7H8N2O2/c10-5-9-7(11)6-2-1-3-8-4-6/h1-4,10H,5H2,(H,9,11)


ID: 1106

chemical graph of compound 1106



InChIKey: JRLOEMCOOZSCQP-UHFFFAOYSA-N
SMILES: CCCCCC(C1=CC(=CC=C1)OCC2=NC3=CC=CC=C3C=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5059
synonyms found at PubChem are:
Rev 5901, REV-5901, 101910-24-1, PF 5901, RG 5901, alpha-Pentyl-3-(2-quinolinylmethoxy)benzenemethanol, 1-[3-(quinolin-2-ylmethoxy)phenyl]hexan-1-ol, CHEMBL8747, MLS000069771, REV-901, PF-5901, SMR000058509, alpha-Pentyl-3-[2-quinolinylmethoxy]benzyl alcohol, Benzenemethanol, alpha-pentyl-3-(2-quinolinylmethoxy)-, 1-(3-(quinolin-2-ylmethoxy)phenyl)hexan-1-ol, SR-01000076105, ACMC-20d0wb, Opera_ID_512, UNII-WNW5RYD8MG, WNW5RYD8MG, AC1L1JIU, D0O8ZE, CBiol_001910, Lopac0_001042, BSPBio_001522, KBioGR_000242, KBioSS_000242, MLS001076522, SCHEMBL678489, AC1Q777J, BML2-G04, CHEBI:91821, CTK4A0391, KBio2_000242, KBio2_002810, KBio2_005378, KBio3_000483, KBio3_000484, JRLOEMCOOZSCQP-UHFFFAOYSA-N, MolPort-003-959-456, Bio1_000196, Bio1_000685, Bio1_001174, Bio2_000242, Bio2_000722, HMS1361M04, HMS1791M04, HMS1989M04, HMS2232F10, HMS3370K08, HMS3402M04, HMS3649O15, BDBM50012434, MFCD00211150, AKOS000278774, AKOS032953945, CCG-205119, LP01042, IDI1_033992, SMP2_000318, NCGC00015895-02, NCGC00015895-03, NCGC00015895-04, NCGC00015895-05, NCGC00015895-06, NCGC00094327-01, NCGC00094327-02, NCGC00094327-03, NCGC00094327-04, [3-(1-hydroxyhexyl)phenoxymethyl]quinoline, LS-186839, LS-187501, EU-0101042, 2-[3-(1-hydroxyhexyl)phenoxymethyl]quinoline, R 5523, 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol, Benzenemethanol,a-pentyl-3-(2-quinolinylmethoxy)-, Benzenemethanol, a-pentyl-3-(2-quinolinylmethoxy)-, Benzenemethanol,|A-pentyl-3-(2-quinolinylmethoxy)-, SR-01000076105-2, SR-01000076105-7, Benzenemethanol,alpha-pentyl-3-(2-quinolinylmethoxy)-, BRD-A68281735-001-03-8, (REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol, 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol (RG 5901), 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol(Rev-5901)


ID: 1107

chemical graph of compound 1107



InChIKey: JROGBPMEKVAPEH-GXGBFOEMSA-N
SMILES: CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3068143
synonyms found at PubChem are:
EMETINE DIHYDROCHLORIDE, 316-42-7, Emetine hydrochloride, Emetine, dihydrochloride, Purum, Emetine HCl, Emetine.2HCl, Amebicide, Emetine dihydrochloride hydrate, l-Emetine dihydrochloride, UNII-U52OG12P96, CCRIS 6237, EINECS 206-259-8, 6',7',10,11-Tetramethoxyemetan dihydrochloride, Emetine hydrochloride [USP], AI3-50600, (+-)-Dehydro-2,3-emetine 2HCl [French], U52OG12P96, Emetan, 6',7',10,11-tetramethoxy-, dihydrochloride, Emetine hydrochloride (USP), 2H-Benzo(a)quinolizine, 1,4,6,7,11b-pentahydro-9,10-dimethoxy-3-ethyl-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl)-, dihydrochloride, (+-)-, 6&prime;,7&prime;,10,11-Tetramethoxyemetan, 2HCl, 2H-Benzo(a)quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-(((1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl)methyl)-, dihydrochloride, (2S,3R,11bS)-, SR-01000000081, SR-01000075853, (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine;dihydrochloride, Prestwick_196, (+-)-Dehydro-2,3-emetine 2HCl, AC1MIF4M, DSSTox_CID_558, CAS-316-42-7, DSSTox_RID_75658, DSSTox_GSID_20558, C29H40N2O4.2HCl, CHEMBL493439, SCHEMBL2382445, 483-18-1 (Parent), DTXSID7020558, CTK8F9434, JROGBPMEKVAPEH-GXGBFOEMSA-N, MolPort-027-835-921, ML081, 2H-Benzo(a)quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-(((1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl)methyl)-, hydrochloride (1:2), (2S,3R,11bS)-, Tox21_200397, Tox21_500460, 6776AF, MFCD00149309, AKOS016010179, EMetineHydrochlorideEmetinehydrochloride, CCG-208338, LP00460, LS-1183, NCGC00093874-01, NCGC00257951-01, NCGC00261145-01, 83029-37-2, LS-40251, E0007, EU-0100460, D03985, E 2375, J-018500, SR-01000000081-4, SR-01000075853-1, (2alpha)-6',7',10,11-tetramethoxyemetan dihydrochloride, EMETINE HYDROCHLORIDE (SEE ALSO: EMETINE (CAS 483-18-1), (2S,3R,11bS)-2-(((R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline dihydrochloride, (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine dihydrochloride


ID: 1108

chemical graph of compound 1108



InChIKey: JRRNZNSGDSFFIR-UHFFFAOYSA-M
SMILES: C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6461
synonyms found at PubChem are:
MEPENZOLATE BROMIDE, Cantil, 76-90-4, Cantilaque, Colibantil, Gastropidil, Cantilon, Colopiril, Delevil, Eftoron, Tralanta, Trancolon, Colum, Trokonil, Mepenzolati bromidum, Bromure de mepenzolate, Bromuro de mepenzolato, Mepenzolate (Bromide), JB 340, Glycophenylate, Cantril, Mepenzolati bromidum [INN-Latin], N-Methyl-3-piperidyl benzilate methobromide, Bromure de mepenzolate [INN-French], Mepenzolone Bromide, N-Methyl-3-piperidyl benzilate methyl bromide, Bromuro de mepenzolato [INN-Spanish], Cantil (TN), N-Methyl-3-piperidyldiphenylglycolate methobromide, 3-Hydroxy-1,1-dimethylpiperidinium bromide benzilate, 3-(2-Hydroxy-2,2-diphenylacetoxy)-1,1-dimethylpiperidin-1-ium bromide, Benzilic acid, 1-methyl-3-piperidyl ester methobromide, 1-Methyl-3-piperidyl benzilate methylbromide, Mepenzolate Methylbromide, NSC 4358, EINECS 200-992-7, Mepenzolate bromide [INN:BAN:JAN], mepenzolic acid, bromine salt, 3-((Hydroxydiphenylacetyl)oxy)-1,1-dimethylpiperidinium bromide, Benzilic acid, ester with 3-hydroxy-1,1-dimethylpiperidinium bromide, Piperidinium, 3-hydroxy-1,1-dimethyl-, bromide, benzilate, DSSTox_CID_3252, Piperidinium, 3-((hydroxydiphenylacetyl)oxy)-1,1-dimethyl-, bromide, Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, DSSTox_RID_76941, DSSTox_GSID_23252, 1-Methyl-3-piperidyl benzilate methyl bromide, 3-{[hydroxy(diphenyl)acetyl]oxy}-1,1-dimethylpiperidinium bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate bromide, C21H26NO3, SMR000058832, SR-01000765452, N-methyl-3-piperidylbenzilate methyl bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide, Prestwick_100, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate, 2-(1,1-dimethylpiperidin-1-ium-3-yl)oxy-2-oxo-1,1-diphenylethanolate, 2-[(1,1-dimethylpiperidinium-3-yl)oxy]-2-oxo-1,1-diphenylethanolate, Mepenzolate bromide [USP:INN:BAN:JAN], AC1L1MKX, CAS-76-90-4, NCGC00016314-01, D0FV3V, AC1Q1R9F, C21H26BrNO3, CHEMBL1724, SCHEMBL99030, MLS001076678, MLS002222165, SPECTRUM1500383, CHEBI:6753, DTXSID4023252, HMS501P18, NSC4358, Mepenzolate bromide (JP15/INN), Mepenzolate bromide (JP17/INN), MolPort-003-666-226, HMS1570C07, HMS1920L05, HMS2091B18, HMS2097C07, HMS2231P11, HMS3259O19, HMS3369A20, HMS3714C07, Pharmakon1600-01500383, Piperidinium,1-dimethyl-, bromide, 25990-43-6 (Parent), NSC-4358, Tox21_110367, 1988AC, CCG-40131, NSC757099, AKOS015962135, Tox21_110367_1, AN-6437, API0000641, CS-3578, NC00518, NSC-757099, KS-0000119J, NCGC00094716-01, NCGC00094716-02, NCGC00178896-05, WLN: T6KTJ A1 A1 COVXQR&R &E, AC-15989, AK116470, CPD000058832, HY-17585, SAM002554910, AX8137418, Benzilic acid,1-dimethylpiperidinium bromide, KB-232690, LS-116643, FT-0671006, Piperidinium,1-dimethyl-, bromide, benzilate, D00720, SR-01000765452-2, SR-01000765452-3, 3-(2-hydroxy-2,2-diphenylacetoxy)-1,1-dimethylpiperidinium bromide, 3-[(Hydroxy-diphenylacetyl)oxy]-1,1-dimethylpiperidinium Bromide, Piperidinium, 3-((hydroxydiphenylacetyl)oxy)-1,1-dimethyl-(VAN), (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate,bromide, 88215-34-3


ID: 1109

chemical graph of compound 1109



InChIKey: JSCUNIPKMPNPFX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)N=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4420318
synonyms found at PubChem are:
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine, CHEMBL97760, 7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol, 286411-09-4, NCGC00015250-01, Lopac-C-5982, D05MCK, AC1O0Y6J, Lopac0_000305, SCHEMBL378998, CTK8E5517, CTK8F7271, HMS3260N12, ZINC8582290, Tox21_500305, BDBM50090697, AKOS028113015, CCG-204400, LP00305, TRA0054236, NCGC00015250-02, NCGC00015250-03, NCGC00015250-04, NCGC00015250-05, NCGC00093754-01, NCGC00093754-02, NCGC00260990-01, 7-chloro-2-phenyl-1,8-naphthyridin-4-ol, 2-Phenyl-7-chloro-1,8-naphthyridine-4-ol, KB-270267, TX-017366, 1,8-Naphthyridin-4-ol,7-chloro-2-phenyl-, EU-0100305, 1,8-Naphthyridin-4-ol, 7-chloro-2-phenyl-, 7-chloro-2-phenyl-1H-1,8-naphthyridin-4-one, C 5982, SR-01000075770, SR-01000075770-1


ID: 1110

chemical graph of compound 1110



InChIKey: JSHLZRQFLJYDSZ-ZVWHLABXSA-N
SMILES: CC(=O)O.C1=CC(=CC=C1C[C@@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5702203
synonyms found at PubChem are:
d[-Arg-2]KYOTORPHAN ACETATE, 74872-77-8, Tyr-D-Arg, AC1NWAUH, SPECTRUM1502182, HMS502M07, DTXSID60420644, [D-Arg2]-Kyotorphin acetate salt, CCG-39591, acetic acid; (2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid


ID: 1111

chemical graph of compound 1111



InChIKey: JSJOTZXJKCXWQC-UHFFFAOYSA-N
SMILES: CC(=O)OC1=C2C(=C(C=C1)Cl)C=CC=N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2718
synonyms found at PubChem are:
chloroacetoxyquinoline, 5-chloro-8-acetoxyquinoline, silital, 10173-02-1, KBio1_000423, Spectrum_001695, Spectrum2_000867, Spectrum5_001169, AC1L1EB5, KBioSS_002175, DivK1c_000423, SPECTRUM1503341, SPBio_000913, 5-Chloro-8-quinolinol acetate, AC1Q61B5, SCHEMBL3691077, CHEMBL1450499, HMS501F05, KBio2_002175, KBio2_004743, KBio2_007311, (5-chloroquinolin-8-yl) acetate, NINDS_000423, HMS1922A18, CCG-40312, IDI1_000423, NCGC00095044-01, NCGC00095044-02, BRD-K98737600-001-02-5


ID: 1112

chemical graph of compound 1112



InChIKey: JTQJFSQQHGPLOX-UHFFFAOYSA-N
SMILES: CC1=C2C(=CS1)C(=O)NC3=CC=CC=C3N2C(=O)CN4CCN(CC4)C.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6419995
synonyms found at PubChem are:
Telenzepine dihydrochloride, 147416-96-4, Telenzepine hydrochloride, SR-01000075349, Prestwick_649, AC1O4WHM, 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride, SCHEMBL184401, CHEMBL1257109, CTK8E8464, DTXSID10423564, JTQJFSQQHGPLOX-UHFFFAOYSA-N, MolPort-003-959-660, HMS1568N08, Tox21_501204, BN0514, SK-871, AKOS024456398, API0009943, CCG-220303, CCG-222508, LP01204, NCGC00094451-01, NCGC00261889-01, 4,9-Dihydro-3-methyl-4-[(4-methyl-1-, RT-015896, B6606, EU-0101204, FT-0759736, T-122, C-55154, B-803-32, B-818-03, B-818-04, J-008354, SR-01000075349-1, SR-01000075349-3, SR-01000075349-6, piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride, 1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one dihydrochloride


ID: 1113

chemical graph of compound 1113



InChIKey: JUCNGUOYQGHBJC-UHFFFAOYSA-N
SMILES: COC(=O)COC1=CC(=C(C=C1Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 1482
synonyms found at PubChem are:
2,4,5-T Methyl ester, 1928-37-6, 2,4,5-T-methyl, 2,4,5-T-methyl [ISO], Methyl (2,4,5-trichlorophenoxy)acetate, UNII-131049BJ6I, 2,4,5-Trichlorophenoxyacetic acid methyl ester, methyl 2-(2,4,5-trichlorophenoxy)acetate, 2,4,5-T-METHYL ESTER, 2,4,5-trichlorophenoxyacetic acid, methyl ester, Acetic acid, (2,4,5-trichlorophenoxy)-, methyl ester, 131049BJ6I, 2,4,5-T Methyl Ester ((2,4,5-Trichlorophenoxy)acetic Acid Methyl Ester), EINECS 217-669-1, Methyl 2,4,5-trichlorophenoxyacetate, methyl(2,4,5-trichlorophenoxy)acetate, NSC 190451, 2,5-T Methyl ester, Spectrum_001865, SpecPlus_000476, 2,4,5-T methyl, 2,4,5-T-methylester, AC1L1BKU, AC1Q3MOE, Spectrum2_001850, Spectrum3_000838, Spectrum4_000678, Spectrum5_001990, BSPBio_002395, KBioGR_001115, KBioSS_002382, SPECTRUM330046, DivK1c_006572, SPBio_001640, CHEMBL1398384, KBio1_001516, KBio2_002378, KBio2_004946, KBio2_007514, KBio3_001895, DTXSID80172875, JUCNGUOYQGHBJC-UHFFFAOYSA-N, ZINC1732130, CCG-39388, NSC190451, Methyl (2,5-trichlorophenoxy)acetate, AKOS008336757, NSC-190451, NCGC00095768-01, NCGC00095768-02, 2,5-Trichlorophenoxyacetic acid methyl ester, Acetic acid,4,5-trichlorophenoxy)-, methyl ester, 2,4,5-T-methyl ester 10 microg/mL in Cyclohexane, J-012478, Acetic acid, (2,4,5-trichlorophenoxy)-, methylated, (2,4,5-TRICHLOROPHENOXY)ACETIC ACID METHYLESTER, 2,4,5-T methyl ester, PESTANAL(R), analytical standard, Acetic acid, (2,4,5-trichlorophenoxy)-, methyl ester (8CI)(9CI)


ID: 1114

chemical graph of compound 1114



InChIKey: JUEUNEKLNSILBZ-BTJKTKAUSA-N
SMILES: C1CC(C2=NC3=CC=CC=C3C(=C2C1)N)O.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5702779
synonyms found at PubChem are:
AC1NWBYA, (Z)-4-hydroxy-4-oxobut-2-enoate; (4-hydroxy-1,2,3,4-tetrahydroacridin-9-yl)azanium, Prestwick_647, AC1O4WHL, Hydroxytacrine maleate (R,S), 9-amino-1,2,3,4-tetrahydroacridin-4-ol; (Z)-but-2-enedioic acid


ID: 1115

chemical graph of compound 1115



InChIKey: JUQLTPCYUFPYKE-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5074
synonyms found at PubChem are:
ritanserin, 87051-43-2, Tiserton, Ritanserine, Ritanserina, Ritanserinum, R-55667, Ritanserine [French], Ritanserinum [Latin], Ritanserina [Spanish], UNII-145TFV465S, C27H25F2N3OS, 6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, R 55,667, MLS000069360, CHEMBL267777, 6-(2-(4-(Bis(p-fluorophenyl)methylene)-piperidino)ethyl)-7-methyl-5H-thiazolo-(3,2-a)pyrimidin-5-one, CHEBI:64195, JUQLTPCYUFPYKE-UHFFFAOYSA-N, 145TFV465S, 6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one, NCGC00015877-06, SMR000058511, DSSTox_CID_22594, DSSTox_RID_80055, DSSTox_GSID_42594, 5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thia, 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-, 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidyl]ethyl]-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[2,3-b]pyrimidin-5-one, CAS-87051-43-2, SR-01000000024, Ritanserin [USAN:BAN:INN], Ritanserin [USAN:INN:BAN], Ritanserin, powder, Tiserton (TN), 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-[2-[4-[Bis(p-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one, Spectrum_001830, Lopac-R-103, AC1L1JJX, Opera_ID_1609, Ritanserin (USAN/INN), Spectrum2_001560, Spectrum3_001023, Spectrum5_001504, D0K8NW, D0N2OM, GTPL97, AC1Q4NH0, cid_5074, N,N-dialkyl-dipeptidylamines, Lopac0_001083, REGID_for_CID_5074, SCHEMBL49227, BSPBio_002805, KBioSS_002335, MLS001148629, DivK1c_000192, ritanserin serotonin antagonist, SPBio_001440, DTXSID9042594, CTK5F7657, HMS500J14, KBio1_000192, KBio2_002332, KBio2_004900, KBio2_007468, KBio3_002025, MolPort-003-666-486, NINDS_000192, HMS2093E19, HMS2233M22, HMS3263I08, HMS3268O04, HMS3373O19, Pharmakon1600-01503421, ZINC538314, BCP13728, Tox21_110251, Tox21_501083, 3726AC, BDBM50001775, BG0387, CCG-39338, MFCD00069341, NSC758470, AKOS015909799, Tox21_110251_1, API0004083, DB12693, LP01083, NSC-758470, IDI1_000192, NCGC00015877-01, NCGC00015877-02, NCGC00015877-03, NCGC00015877-04, NCGC00015877-05, NCGC00015877-07, NCGC00015877-08, NCGC00015877-09, NCGC00015877-11, NCGC00022447-03, NCGC00022447-04, NCGC00022447-05, NCGC00178460-01, NCGC00261768-01, AJ-23387, AN-16598, CC-34269, SBI-0051053.P003, AX8150457, LS-156826, B6898, EU-0101083, FT-0630948, R-103, KS-00001841, D05738, AB00053288_14, 051R432, C-22775, L001003, SR-01000000024-3, SR-01000000024-4, BRD-K40887525-001-02-9, BRD-K40887525-001-14-4, ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, I14-31889, 6-[2-[4-bis(4-Fluorophenyl)methylene]-1-piperidinyl]-, (+)-6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one, (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 5H-Thiazolo[3,2-a]pyrimidin-5-one,6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-(2-(4-(Bis(4-fluorophenyl);methylene);piperidin-1-yl);ethyl);-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-(4-(Bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo((3,2-a)pyrimidin-5-one, 6-(2-(4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl)ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one #, 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin), 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin), 6-[2-[4-[bis (4-Fluorophenyl)- methylene]-1-piperidinyl]-ethyl]- 5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis (4-Fluorophenyl)-methylene]-1-piperidinyl]-ethyl]-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)-methylene]-1-piperidinyl]-ethyl]-5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)-methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]-pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, E2J


ID: 1116

chemical graph of compound 1116



InChIKey: JVGBTTIJPBFLTE-UHFFFAOYSA-N
SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CC4COC5=CC=CC=C5O4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5268
synonyms found at PubChem are:
Spiroxatrine, 1054-88-2, Spiroxatrinum, Spiroxatrine [INN], SPIROXAMIDE, Spiroxatrine (R 5188), Spiroxatrinum [INN-Latin], Espiroxatrina [INN-Spanish], R 5188, NSC 665322, CHEMBL300555, NSC665322, NCGC00015908-05, 8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one, DSSTox_CID_25198, DSSTox_RID_80744, DSSTox_GSID_45198, Espiroxatrina, 1,3,8-Trianaspiro(4.5)decane-4-one,8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-, 8-(1,4-Benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-trianaspiro(4,5)decane-4-one, 8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one, (+/-)-8-[(2,3-Dihydro-1,4-Benzodioxin-2-yl)Methyl]-1-Phenyl-1,3,8-Triazaspiro [4,5]Decan-4-one, CAS-1054-88-2, SR-01000075579, Biomol-NT_000104, D0MU4A, GTPL53, AC1L1JZ3, Lopac0_001142, BPBio1_001395, SCHEMBL1255303, DTXSID3045198, CHEBI:91845, CTK8G3191, MolPort-003-983-690, HMS2089G17, HMS3263F05, HMS3266D15, Tox21_110260, Tox21_501142, BDBM50020192, BN0501, AKOS024458589, Tox21_110260_1, CCG-205216, LP01142, NSC-665322, NCGC00015908-03, NCGC00015908-04, NCGC00015908-06, NCGC00015908-07, NCGC00015908-08, NCGC00015908-09, NCGC00024696-02, NCGC00024696-03, NCGC00024696-04, NCGC00024696-05, NCGC00261827-01, NCI60_022532, LS-171963, EU-0101142, S-103, R-5188, L001271, J-001433, SR-01000075579-1, SR-01000075579-3, BRD-A72483914-001-01-1, BRD-A72483914-001-02-9, 8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro(4,5)-decan-4-one, 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, ( inverted exclamation markA)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one


ID: 1117

chemical graph of compound 1117



InChIKey: JVKYZPBMZPJNAJ-OQFNDJACSA-N
SMILES: C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 65727
synonyms found at PubChem are:
Solanidine, Solanidin, Solatubin, Solatubine, 22R,25S-Solanidanine, 80-78-4, 22R,25S-Solanidine, Solanid-5-en-3beta-ol, 3-beta-Solanid-5-en-3-ol, Solanid-5-en-3-beta-ol, UNII-W7801OHM8B, CCRIS 6508, EINECS 201-309-5, NSC 76025, BRN 0045370, W7801OHM8B, CHEBI:28374, NSC76025, Solanid-5-en-3.beta.-ol, Solanid-5-en-3-ol, (3.beta.)-, Solanid-5-en-3-ol, (3beta)-, Solanid-5-en-3-ol, Solanid-5-en-3b-ol, 4-21-00-01398 (Beilstein Handbook Reference), SCHEMBL336752, (3beta)-solanid-5-en-3-ol, AC1L23U5, Solanid-5-en-3beta-ol(8CI), CHEMBL1980466, Solanid-5-en-3beta-ol (8CI), 3-b-Solanid-5-en-3-ol(9cl), JVKYZPBMZPJNAJ-OQFNDJACSA-N, 3-beta-Solanid-5-en-3-ol(9cl), Solanid-5-en-3-ol, (3-beta)-, Solanidine, >=97.0% (HPLC), ZINC8220551, LMST01150007, NSC-76025, solanid-5-en-3-ol (ACD/Name 4.0), CC-34501, NCI60_041673, Solanid-5-en-3-ol, (3beta)- (9CI), LS-145586, Solanid-5-en-3-ol, (3-beta)- (9CI), C06543, C-23896


ID: 1118

chemical graph of compound 1118



InChIKey: JWBOIMRXGHLCPP-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4211
synonyms found at PubChem are:
mitotane, Mitotan, 53-19-0, Lysodren, Chlodithane, Chloditan, o,p'-DDD, Khlodithan, Chlodithan, Mitotano, 2,4'-Ddd, 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, Mitotanum, Mitotanum [INN-Latin], o,p'-TDE, 2,4'-Dichlorodiphenyldichloroethane, o,p-Tde, Khloditan, Mytotan, 1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene, NCI-C04933, o,p'-Dichlorodiphenyldichloroethane, ortho,para-DDD, Mitotano [INN-Spanish], 2,4'-Dichlorophenyldichlorethane, o,p-DDD, Opeprim, 1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene, CB313, Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-, DDD, o,p'-, CB 313, NSC 38721, Lysodren (TN), Mitotane [USAN:INN:JAN], 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane, 2-(o-Chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloroethane, C14H10Cl4, CCRIS 4397, 1,1-Dichloro-2,2-bis(2,4'-dichlorophenyl)ethane, HSDB 3240, NSC38721, 1,1-Dichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl)ethane, 2,2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane, EINECS 200-166-6, CB-313, (o,p)-DDD, Mitotane (JAN/USP/INN), BRN 2056007, AI3-07575, 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene, Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-, Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-, Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-, NSC-38721, (2,4'-Dichlorodiphenyl)dichloroethane, NCGC00015226-07, (+-)-1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, DSSTox_CID_372, C 3010, DSSTox_RID_75548, DSSTox_GSID_20372, 2,4 -Dichlorodiphenyldichloroethane, Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-, (+-)-, ortho,para DDD, CAS-53-19-0, SMR000326696, SR-01000075751, Prestwick_75, Ethane,1-dichloro-, Mitotane (Lysodren), Piprine-DDD, O-, Mitotane [USAN:USP:INN:BAN:JAN], PubChem14974, Spectrum_001959, DDD-o,p', AC1L1HNV, Spectrum2_000916, Spectrum3_000869, Spectrum4_000709, Spectrum5_002060, PS694_SUPELCO, D0Z5OE, (o,p')-DDD, SCHEMBL4040, CHEMBL1670, Lopac0_000251, WLN: GYGYR BG&R DG, BSPBio_002517, KBioGR_001237, KBioSS_002513, SPECTRUM330082, MLS001335899, MLS001335900, MLS002152914, MLS002153233, DivK1c_000703, SPBio_000792, AC1Q3H13, CHEBI:6954, GTPL6957, Mitotane, >=98% (HPLC), DTXSID9020372, 2,4'-DDD, analytical standard, CTK8E2992, HMS502D05, KBio1_000703, KBio2_002505, KBio2_005073, KBio2_007641, KBio3_002017, JWBOIMRXGHLCPP-UHFFFAOYSA-N, MolPort-001-779-578, NINDS_000703, HMS1923K19, HMS2091E07, HMS2232C16, HMS3260D04, HMS3369H10, HMS3655G06, HMS3715H07, Pharmakon1600-00330082, BCP11663, 2,4 inverted exclamation marka-DDD, Tox21_110103, Tox21_302804, Tox21_500251, CCG-40014, LS-185, MFCD00000850, NSC755849, s1732, 1,2-bis(2,4'-dichlorophenyl)ethane, AKOS006028802, Tox21_110103_1, Bristol Myers Squibb Brand of Mitotane, Bristol-Myers Squibb Brand of Mitotane, CS-1500, DB00648, LP00251, MCULE-2068358149, NSC-755849, IDI1_000703, NCGC00015226-02, NCGC00015226-03, NCGC00015226-04, NCGC00015226-05, NCGC00015226-06, NCGC00015226-08, NCGC00015226-09, NCGC00015226-10, NCGC00015226-11, NCGC00015226-12, NCGC00091374-01, NCGC00091374-02, NCGC00091374-03, NCGC00091374-04, NCGC00091374-05, NCGC00091374-06, NCGC00256452-01, NCGC00260936-01, 2,4'-DDD 10 microg/mL in Cyclohexane, AN-41639, AS-11690, HY-13690, NCI60_003688, SC-18530, 2,4'-DDD 100 microg/mL in Cyclohexane, SBI-0050239.P004, AB0010565, KB-146519, TR-018813, EU-0100251, FT-0605518, ST51016017, EN300-37268, 2,4'-DDD, PESTANAL(R), analytical standard, D00420, W-5031, AB00052337-09, AB00052337_10, 000M850, SR-01000075751-1, SR-01000075751-3, SR-01000075751-6, 2,4'-(2,2-dichloroethane-1,1-diyl)bis(chlorobenzene), Z425389592, 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane, 1-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-2-chlorobenzene, Ethane,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-, 1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene #, Mitotane, United States Pharmacopeia (USP) Reference Standard, Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-(8CI), Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- (8CI), 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, analytical standard, o,p'-DDD|||1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane|||Mitotane, 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane for diagnostic uses (cancer investigation), >=98% (HPLC), 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, for diagnostic uses (cancer investigation), >=98% (HPLC)


ID: 1119

chemical graph of compound 1119



InChIKey: JWDYCNIAQWPBHD-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1OCC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4059
synonyms found at PubChem are:
mephenesin, 59-47-2, Decontractyl, Cresoxydiol, Memphenesin, Mephedan, Mephenesine, Anatensin, Cresodiol, Decontractil, Dioloxol, Lissenphan, Lissephen, Mefenesina, Mephelor, Mephesin, Myodetensin, Myodetensine, Atensin, Curaril, Sinan, Kresoxypropandiol, Cresoxypropanediol, Cresossidiolo, Curarythan, Seconesinz, Spartoloxin, Spartoloxyn, Curythan, Daserol, Diloxol, Dioloxal, Findolar, Findolor, Glukresin, Glykresin, Glyotol, Halabar, Kinavosyl, Mephate, Mepherol, Mephosal, Mephson, Mervaldin, Mianesina, Miolisina, Moctynol, Myanesin, Myastenin, Myocuran, Myolysin, Myosera, Myoserol, Myoxane, Nembusen, Nephelor, Noctynol, Oranixon, Prolaxin, Proloxin, Relaxant, Relaxar, Relaxil, Relaxyl, Renarcol, Sansdolor, Saserol, Spasmolyn, Stilalgin, Thioxidil, Thoxidil, Tokerol, Tolansin, Tolbart, Tolhart, Tolofren, Tolosate, Toloxyn, Tolserol, Tolulexin, Tolulox, Tolydrin, Tolynol, Tolyspaz, Torulox, Anxine, Avesyl, Avosyl, Avoxil, Avoxyl, Daserd, Glytol, Mephin, Myanil, Myanol, Myasin, Myolax, Myopan, Myopen, Myopna, Myoten, Myoxyl, Ortol, Prolax, Temian, Tolax, Tolcil, Tolsil, Tolsin, Xeral, Rhex regulans, Walko-Nesin, Cresossipropandiolo, Rhex 'hobeino', o-Cresyl glycerol ether, Glyceryl o-tolyl ether, Ageflex CGE, o-Cresol glyceryl ether, 3-(2-Methylphenoxy)propane-1,2-diol, 1-o-Tolylglycerol ether, 1,2-Propanediol, 3-(2-methylphenoxy)-, Mephenesinum, Mephensin, Myolyseen, 3-(2-Methylphenoxy)-1,2-propanediol, 3-(o-Tolyloxy)propane-1,2-diol, o-Kresol-glycerinaether, BYK-M 1, 3-o-Toloxy-1,2-propanediol, BDH 312, 1-Ortho-tolylglycerol ether, 3-(2-Tolyloxy)-1,2-propanediol, Walconesin, 3-(o-Methylphenoxy)-1,2-propanediol, Mycocuran, MC 2303, RP 3602, SQ 1156, 3-(o-Tolyloxy)-1,2-propanediol, Mefenesina [INN-Spanish], Mephenesine [INN-French], Mephenesinum [INN-Latin], 1,2-Dihydroxy-3-(2-methylphenoxy)propane, o-Cresyl alpha-glyceryl ether, A 1141, alpha-(o-Tolyl)glyceryl ether, o-Kresol-glycerinaether [German], C10H14O3, EINECS 200-427-4, NSC 25234, BRN 2047373, Mefensina, Rex regulans, 1,2-PROPANEDIOL, 3-(o-TOLYLOXY)-, Walco-Nesin, o-Cresyl .alpha.-glyceryl ether, .alpha.-(o-Tolyl)glyceryl ether, NSC25234, alpha,beta-Dihydroxy-gamma-(2-methylphenoxy)propane, component of Tolagesic, NCGC00094908-01, DSSTox_CID_3254, 1, 3-(o-tolyloxy)-, DSSTox_RID_76942, WLN: Q1YQ1OR B1, DSSTox_GSID_23254, 1, 3-(2-methylphenoxy)-, .alpha.,.beta.-Dihydroxy-.gamma.-(2-methylphenoxy)propane, Mephenesin [INN:BAN], SR-05000001772, Mephenesin [INN:BAN:NF], Rhex, CAS-59-47-2, Tolserol (TN), Mephenesin (INN), Prestwick_577, Mephenesin, 98%, 1-(o-tolyl)glycerol, 1-(2-tolyl)glycerol, Spectrum_001402, AC1L1HBM, Prestwick0_000178, Prestwick1_000178, Prestwick2_000178, Prestwick3_000178, Spectrum2_001418, Spectrum3_000908, Spectrum4_001007, Spectrum5_001199, (.+/-.)-Mephenesin, 1-(2-methylphenyl)glycerol, SCHEMBL25448, BSPBio_000075, KBioGR_001473, KBioSS_001882, DivK1c_000076, SPECTRUM1501140, SPBio_001496, SPBio_001996, BPBio1_000083, CHEMBL229128, DTXSID4023254, CHEBI:94398, CTK8G0796, HMS500D18, KBio1_000076, KBio2_001882, KBio2_004450, KBio2_007018, KBio3_001856, KS-00001FBQ, NSC8134, JWDYCNIAQWPBHD-UHFFFAOYSA-N, MolPort-003-666-365, NINDS_000076, HMS1568D17, HMS1921J09, HMS2092F17, HMS2095D17, HMS3712D17, Pharmakon1600-01501140, EBD70999, HY-B1283, NSC-8134, NSC36140, NSC50788, GLYCEROL-1-(O-TOLYL) ETHER, Tox21_111356, CCG-38970, NSC-25234, NSC-36140, NSC-50788, NSC757857, SBB056988, STL430456, AKOS015912866, Tox21_111356_1, API0003293, CS-5340, MCULE-1125347766, NSC-757857, IDI1_000076, NCGC00094908-02, NCGC00094908-03, NCGC00094908-06, BBV-39686544, 3-[(2-methylphenyl)oxy]propane-1,2-diol, SBI-0051654.P002, AB1004849, LS-120750, AB00052216, FT-0628209, ST50407278, W0052, 3-(2-Methylphenoxy)-1,2-propanediol, 98%, D02595, AB00052216_04, SR-05000001772-1, SR-05000001772-2, SR-05000001772-3, BRD-A55469827-001-01-7, I14-49387, 3-(2-Methylphenoxy)-1,2-propanediol; Mephenesin; 3-(o-Tolyloxy)-1,2-propanediol


ID: 1120

chemical graph of compound 1120



InChIKey: JWQRAXTWDYUBFI-UHFFFAOYSA-N
SMILES: C=CCN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957703
synonyms found at PubChem are:
SKF 77434 hydrobromide, 300561-58-4, N-Allyl-(+/-)-SKF-38393 hydrobromide, SKF-77434 hydrobromide, CHEBI:63978, N-Allyl-( inverted exclamation markA)-SKF-38393 hydrobromide, 3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 1-phenyl-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diolhydrobromide, 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide, N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, SR-01000075405, (+/-)-SKF 38393, N-allyl-, hydrobromide, EU-0101143, MLS002153340, CHEMBL1256885, DTXSID5042611, SCHEMBL11288446, CTK8E6902, AOB5002, MolPort-003-959-443, Tox21_501143, AKOS024456732, CCG-222447, LP01143, (+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, NCGC00094408-01, NCGC00261828-01, SMR001230751, NCG-C00094408-01, (y)-SKF 38393, N-allyl-, hydrobromide, RT-014252, (?)-SKF 38393, N-allyl-, hydrobromide, N-Allyl-(A+/-)-SKF-38393 hydrobromide, S-168, J-017750, SR-01000075405-1, SR-01000075405-3, ( inverted exclamation markA)-SKF-77434 hydrobromide, SKF-77434 Hydrobromide (N-Allyl-SKF38393 HBr), ( inverted question mark)-SKF 38393, N-allyl-, hydrobromide, N-Allyl-(+/-)-SKF-38393 hydrobromide, solid, >=98% (HPLC), 1-phenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, 2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol hydrobromide, ( inverted exclamation markA)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, ( inverted question mark)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)


ID: 1121

chemical graph of compound 1121



InChIKey: JWRMHDSINXPDHB-DCPWPRNHSA-N
SMILES: C[C@@H]1CC2C3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5702055
synonyms found at PubChem are:
FLUMETHAZONE PIVALATE, AC1NWAMI, Spectrum_000691, Spectrum2_001265, Spectrum3_000431, Spectrum4_000553, Spectrum5_000708, BSPBio_002042, KBioGR_001245, KBioSS_001171, DivK1c_000304, SPECTRUM1500300, SPBio_001230, SCHEMBL7864998, HMS500P06, KBio1_000304, KBio2_001171, KBio2_003739, KBio2_006307, KBio3_001262, NINDS_000304, HMS1920O12, HMS2091F13, Pharmakon1600-01500300, CCG-39130, NSC757032, NSC-757032, IDI1_000304, NCGC00178849-01, SBI-0051383.P003, AB00051994_02, SR-05000002044, SR-05000002044-1, BRD-A50064262-001-03-9, [2-[(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate


ID: 1122

chemical graph of compound 1122



InChIKey: JXIGVERNCHIKAI-UHFFFAOYSA-N
SMILES: C1(=NC=CC=C1)C1C=C(C(=O)O)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 28293307
synonyms found at PubChem are:
716362-11-7, 3-(pyridin-2-yl)-5-isoxazolylcarboxylic acid, SCHEMBL3522095, JXIGVERNCHIKAI-UHFFFAOYSA-N, ZINC19726651, AKOS009284238, MCULE-7796360664, 3-Pyridin-2-ylisoxazole-5-carboxylic acid, 3-(2-pyridinyl)-5-isoxazolecarboxylic acid, FT-0714736, 3-(pyridin-2-yl)-1,2-oxazole-5-carboxylic acid


ID: 1123

chemical graph of compound 1123



InChIKey: JXOHGGNKMLTUBP-HSUXUTPPSA-N
SMILES: C1[C@H]([C@@H]([C@@H](C=C1C(=O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 8742
synonyms found at PubChem are:
shikimic acid, 138-59-0, shikimate, L-Shikimic acid, (-)-Shikimic acid, (3R,4S,5R)-3,4,5-Trihydroxycyclohex-1-enecarboxylic acid, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, CCRIS 7681, HSDB 3537, UNII-29MS2WI2NU, 3alpha,4alpha,5beta-Trihydroxy-1-cyclohexene-1-carboxylic acid, (-)-Shikimate, Bracken fern toxic component, EINECS 205-334-2, NSC 59257, 1-cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R,4S,5R)-, 29MS2WI2NU, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta))-, CHEMBL290345, CHEBI:16119, 3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid, C7H10O5, JXOHGGNKMLTUBP-HSUXUTPPSA-N, [3R-(3alpha,4alpha,5beta)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, (3R,4S,5R)-3,4,5-trihydroxycyclohexene-1-carboxylic acid, (3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid, (4S,3R,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta))- (9CI), SKM, SMR001306700, SR-01000632403, Skikimate, Shicimic Acid, L-Shikimate, 2aay, 4guj, Spectrum_001232, 1we2, 2aa9, SpecPlus_000488, AC1L1RLY, Spectrum2_001508, Spectrum3_001541, Spectrum4_001853, Spectrum5_000386, 1-cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, Shikimic acid, >=99%, bmse000114, EC 205-334-2, SCHEMBL43377, BSPBio_002982, KBioGR_002287, KBioSS_001712, MLS002207031, MLS004256600, DivK1c_006584, SPECTRUM1502256, L-(-)-SHIKIMIC ACID, SPBio_001555, AC1Q59I8, MEGxp0_001939, DTXSID4032039, KBio1_001528, KBio2_001712, KBio2_004280, KBio2_006848, KBio3_002482, KS-00000EYL, MolPort-002-507-279, Shikimic acid, analytical standard, HY-N0130, ZINC3860720, BDBM50281998, CCG-38884, CS-068, CS0026, MFCD00066278, SBB012371, AKOS004119897, AC-8010, AN-8431, EBD2197575, LS-2110, MCULE-9138847690, SDCCGMLS-0066740.P001, SMP1_000326, NCGC00142601-01, NCGC00142601-02, AJ-46044, AS-13905, ST069316, AB0071582, ST2402355, TL8000880, TR-032693, CS-0007856, FT-0080765, N1829, S0038, 3,4,5-Trihydroxycyclohex-1-enecarboxylicacid, C00493, M-2736, 103690-EP2277898A2, 103690-EP2301911A1, 138S590, Q-100148, SR-01000632403-1, SR-01000632403-4, SR-01000632403-5, (-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, B1A53F8A-8664-405D-8370-A9785ADD2D0B, (3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic Acid, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R,4S,5R)- (9CI), 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta)), Shikimic acid [3R-(3alpha,4alpha,5beta)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, InChI=1/C7H10O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1,4-6,8-10H,2H2,(H,11,12)/t4-,5-,6-/m1/s


ID: 1124

chemical graph of compound 1124



InChIKey: JXSVIVRDWWRQRT-UYDOISQJSA-N
SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 119034
synonyms found at PubChem are:
Asiatic acid, 464-92-6, Dammarolic acid, UNII-9PA5A687X5, NSC 166063, CHEBI:2873, CHEMBL404313, JXSVIVRDWWRQRT-UYDOISQJSA-N, 9PA5A687X5, Asiantic acid, (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid, Asiatic-acid, HSDB 7662, NSC-166063, 2,3,23-trihydroxyurs-12-en-28-oic acid, (2|A,3|A)-2,3,23-trihydroxyurs-12-en-28-oic acid, Asiatic acid, 97%, AC1Q5QHS, D0LC7K, AC1L3O2W, SCHEMBL3285999, 2alpha,23-Dihydroxyursolic acid, Asiatic acid, analytical standard, MolPort-009-649-413, ZX-AFC002762, ZINC8221271, BDBM50241487, MFCD00238541, AKOS007930256, Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-, CCG-208549, MCULE-1974040943, NCGC00346584-02, AN-45109, Asiatic acid;HSDB 7662;464-92-6, CC-24192, LS-193512, N1356, V1794, C08617, 464A926, C-22852, Q-100489, Asiatic acid, >=98% (HPLC), from Centella asiatica, BRD-K35079116-001-03-3, (2alpha,3beta)-2,3,23-trihydroxyurs-12-en-28-oic acid, Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2alpha,3beta,4alpha)-, Urs-12en-28-oic acid, 2,3,23-trihydroxy-, (2alpha, 3beta, 4alpha)-, (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid, (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-, 0AS


ID: 1125

chemical graph of compound 1125



InChIKey: JXUGSXOSZMZDGF-UHFFFAOYSA-N
SMILES: CC(=O)OC1=C(C2=C(C=C1)C3C4=CC(=C(C(=C4CC3(CO2)O)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708558
synonyms found at PubChem are:
HAEMATOXYLIN PENTAACETATE, KBio2_001070, Spectrum_000590, SpecPlus_000116, AC1O8FDA, Spectrum3_001290, Spectrum4_001596, BSPBio_002899, KBioGR_002212, KBioSS_001070, SPECTRUM240944, DivK1c_006212, CHEMBL1528876, CHEBI:91569, KBio1_001156, KBio2_003638, KBio2_006206, KBio3_002119, CCG-214407, SDCCGMLS-0066555.P001, NCGC00095555-01, NCGC00095555-02, SR-05000002737, SR-05000002737-1, BRD-A18932057-001-01-1, (4,8,9,10-tetraacetyloxy-6a-hydroxy-7,11b-dihydro-6H-indeno[2,1-c]chromen-3-yl) acetate


ID: 1126

chemical graph of compound 1126



InChIKey: JXXCENBLGFBQJM-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CC(CC(=O)O)O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5970
synonyms found at PubChem are:
461-05-2, DL-Carnitine hydrochloride, Carnitine chloride, Monocamin, Carnitine hydrochloride, Carnitine DL- hydrochloride, bicarnesine, (+-)-Carnitine hydrochloride, (+/-)-Carnitine hydrochloride, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, d,l-Carnitine hydrochloride, Vitamin BT Hydrochloride, EINECS 200-305-0, EINECS 207-309-1, Carnitine chloride [JAN], (+/-)-Carnitine chloride, (3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, DL-CARNITINE HCL, Carnitine chloride (JAN), L-Carnitine chloride, C7H15NO3.HCl, ( inverted exclamation markA)-Carnitine (chloride), 56-99-5, 3-Hydroxy-4-(trimethylammonio)butyrate Hydrochloride, L-Carnitine hydrochloride, AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride (1:1), 3-carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride, CARNITINE (dl) HYDROCHLORIDE, Carnitine DL- HCl, NCGC00094816-01, 3-hydroxy-4-(trimethylamino)butanoic acid, chloride, Carnitine L-form hydrochloride, LC-80, EINECS 229-663-6, carnitinhydrochlorid, carnitinium chloride, Vitamin B<v>T, Entomin (TN), 461-05-2[rn], AC1L1LIU, AC1Q1SGT, (+-)-carnitine chloride, l-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, (-)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, (R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, 1-propanaminium-3-carboxy-2-hydroxy-N,N,N-trimethyl hydroxide, MLS001332614, SCHEMBL357561, SPECTRUM1500624, (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, (R)-, AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, (-)-, CHEMBL1439419, CTK1F3269, HMS501H12, MolPort-001-795-078, HMS1921K21, HMS2231O13, HMS3370L12, HMS3372B07, HMS3651A18, Pharmakon1600-01500624, HY-B1453, GM8717, MFCD00011904, NSC757390, s2293, SBB003568, AKOS015892785, API0002444, CCG-213758, CS-6453, NSC-757390, VA11215, VC30976, DL-Carnitine hydrochloride, 98% 25g, NCGC00094816-02, CPD000875216, gastric and pancreatic secretion stimulant, LS-17066, LS-17067, LS-17069, SAM002564199, SMR000875216, AB2000550, FT-0625450, ST24046652, ST50983925, D03273, (+/-)-Carnitine hydrochloride, >=98% (TLC), [-]- beta-Hydroxy-gamma-trimethylaminobutyric acid, I04-1030, I04-1123, (2,4-dihydroxy-4-oxobutyl)-trimethylazanium chloride, (+/-)-Carnitine hydrochloride, purum, >=99.0% (AT), beta-Hydroxy-beta-(trimethylammonio)butyrate hydrochloride, beta-Hydroxy-gamma-(trimethylammonio)butyrate hydrochloride, Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, (+-)-, 17360-44-0, 3673-49-2, 51479-53-9, 5852-94-8, 6801-68-9, 68960-71-4, 856319-55-6, dl-carnitine chloride, C-1990, DSSTox_CID_25850, DSSTox_RID_81172, DSSTox_GSID_45850, CAS-461-05-2, C7H16ClNO3, 16224-32-1, DTXSID8045850, CTK8G4044, JXXCENBLGFBQJM-UHFFFAOYSA-N, MolPort-005-932-344, KS-00000G3J, Tox21_111339, GM4580, MFCD00066100, AKOS015899583, Tox21_111339_1, CCG-208519, MCULE-4215013152, TRA0073139, NCGC00263894-02, AK163426, AS-11627, S447, SC-25562, ST51039971, (-)-beta-Hydroxy-gamma-(trimethylammonio)butyrate, I14-058, I14-0058, I14-11235


ID: 1127

chemical graph of compound 1127



InChIKey: JXYWFNAQESKDNC-BTJKTKAUSA-N
SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5284451
synonyms found at PubChem are:
PYRILAMINE MALEATE, Mepyramine maleate, 59-33-6, Anisopyradamine, Histosol, Minihist, Diaminide maleate, Paraminyl maleate, Antihist, Histatex, Histine, Paramal, Pymafed, Pyraninyl, Renstamin, Histan, Pyramal maleate, Stangen maleate, Anthisan maleate, Statomin maleate, Thylogen maleate, Pyra-Maleate, Pyrilamine maleate salt, Neoantergan maleate, Pyranilamine maleate, Pyranisamine maleate, Kriptin maleate, Neo-Antergan maleate, Pyra maleate, Prefrin A, Dorantamin maleate, 2786 R.P. maleate, Enrumay, Histavet-P (veterinary), Mepyramine hydrogen maleinate, Mepyramine maleate salt, Pyma, Histavet-P, Mepiramine maleate, Midol Maximum Strength PMS, Pyrilamine maleate [USAN], UNII-R35D29L3ZA, component of Pyrdex, Pymafed (TN), pyranilamine m aleate, CCRIS 1330, NSC 3604, EINECS 200-422-7, Pyrilamine maleate (USP), component of Endotussin-NN, MLS000069668, R35D29L3ZA, N-Dimethylaminoethyl-N-p-methoxy-alpha-aminopyridine maleate, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine maleate (1:1), N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyridyl)ethylenediamine maleate, N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine maleate, 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), SMR000058495, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine bimaleate, 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine bimaleate, P 5514, Pyridine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-, maleate (1:1), 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1), 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), AH, N,N-dimethyl-N'-{[4-(methyloxy)phenyl]methyl}-N'-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate, PYRILAMINE MALEATE (SEE ALSO PYRILAMINE, CAS 91-84-9), 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine maleate, 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine maleate, N-(Dimethylamino)ethyl-N-(p-methoxy)-.alpha.-aminopyridine maleate, N-(dimethylaminoethyl)-N-(p-methoxyphenyl)-alpha-aminopyridine maleate, N-(p-me thoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine maleate, N-(p-methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine maleate, N-(p-Methoxybenzyl)-N',N'-dimethyl-N-.alpha.-pyridylethylenediamine maleate, N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine but-2-enedioate, N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, 1,2-Ethanediamine, N1-((4-methoxyphenyl)methyl)-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1), CAS-59-33-6, SR-01000000225, Bimaleate, Pyrilamine maleate [USAN:USP], Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1), (Z)-but-2-enedioic acid;N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine, Prestwick_634, Opera_ID_1702, DSSTox_CID_1216, D01NJI, D03GFW, AC1NR4H4, DSSTox_RID_76015, DSSTox_GSID_21216, SCHEMBL27430, MLS001148634, SPECTRUM1500519, CHEMBL1201006, DTXSID4021216, HMS500I17, NSC3604, C16H21N3O.C4H4O4, JXYWFNAQESKDNC-BTJKTKAUSA-N, MolPort-003-666-277, HMS1568J20, HMS1920N10, HMS2092E11, HMS2095J20, HMS2234I23, HMS2234I24, HMS3262B22, HMS3712J20, Pharmakon1600-01500519, HY-B1281, NSC-3604, Tox21_200514, Tox21_500890, BG0398, CCG-39244, LS-251, MFCD00069333, NSC757305, AKOS015950805, LP00890, NSC-757305, NCGC00094209-01, NCGC00094209-02, NCGC00094209-03, NCGC00094209-04, NCGC00094209-05, NCGC00258068-01, NCGC00261575-01, SMR000653462, AB1004850, KB-166333, B6396, CS-0013057, EU-0100890, P2369, ST24031459, D05660, WLN: T6NJ BN1R DO1&2N1&1 &OV1U1VO, SR-01000000225-2, SR-01000000225-4, SR-01000000225-5, SR-01000000225-8, N-(p-Methoxybenzyl)-N,2-ethanediamine, maleic acid salt, 2-((2-(dimethylamino)ethyl )(p-methoxybenzyl)amino)pyridine maleate, 2-[(2-dimethylaminoethyl)(p-methoxybenzyl)amino]pyridine maleate, Mepyramine maleate, European Pharmacopoeia (EP) Reference Standard, 2-[[2-(Dimethylamino)ethyl]( p-methoxybenzyl)amino]pyridine maleate (1:1), Pyrilamine maleate, United States Pharmacopeia (USP) Reference Standard, 1, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine Maleate, N-(p-Methoxybenzyl)-N,N'-dimethyl-N-2-pyridyl-1,2-ethanediamine, maleic acid salt, Pyrilamine maleate, Pharmaceutical Secondary Standard; Certified Reference Material, (Z)-but-2-enedioic acid; N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine, 5572-06-5, Mepyramine maleate salt; N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,N inverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,N inverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,Ninverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine (2Z)-2-Butenedioate, N1-[(4-Methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-1,2-ethanediamine (2Z)-2-Butenedioate, [2-(dimethylamino)ethyl][(4-methoxyphenyl)methyl]-2-pyridylamine, (2Z)but-2-en edioic acid, SBB057008, AKOS024362796, ST50993906


ID: 1128

chemical graph of compound 1128



InChIKey: JXZCUTPQSYPHMT-UHFFFAOYSA-N
SMILES: CC1=CC(=NC2=CC=CC=C12)NC3=CC=C(C=C3)Br

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"GL Lukacs" "O Zegarra-Moran" "LJ Galietta" "AS Verkman" "K Du" "N Pedemonte" "E Caci"


CID is 768745
synonyms found at PubChem are:
N-(4-bromophenyl)-4-methylquinolin-2-amine, GNF-Pf-268, (4-Bromo-phenyl)-(4-methyl-quinolin-2-yl)-amine, 324526-70-7, AC1LGCGR, BAS 00437701, CBMicro_025025, Oprea1_246881, Oprea1_826009, MLS001077237, SCHEMBL838429, CHEMBL600111, MolPort-001-932-878, HMS2789N21, ZINC248679, CCG-12150, STL383355, AKOS003192686, MCULE-3821665810, SMR000473020, BIM-0025121.P001, N-(4-bromophenyl)-N-(4-methyl-2-quinolyl)amine, SR-01000400434, SR-01000400434-1


ID: 1129

chemical graph of compound 1129



InChIKey: JYGXADMDTFJGBT-VWUMJDOOSA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5754
synonyms found at PubChem are:
hydrocortisone, Cortisol, 50-23-7, Acticort, Cetacort, Hydrocortisyl, Cobadex, Hydrasson, Cortef, Hycort, Hytone, Signef, 17-Hydroxycorticosterone, Optef, Kendall's compound F, Hydrocortone, Cortanal, Cortenema, Corticreme, Cortifan, Cortiment, Cortispray, Cortonema, Dermolate, Efcorbin, Efcortelan, Ficortril, Genacort, Hycortol, Hycortole, Permicort, Proctocort, Tarcortin, Traumaide, Alacort, Cleiton, Cortril, Dihydrocostisone, Hytone lotion, Hidro-Colisona, Hydro-Adreson, Scheroson F, Incortin-H, Reichstein's substance M, Cort-Dome, Domolene-HC, Epiderm H, Esiderm H, Otosone-F, Polcort H, Cortolotion, Cortoxide, Cremesone, Eldercort, Heb-Cort, Maintasone, Delacort, Dioderm, Eldecort, Epicort, Mildison, Penecort, Rectoid, Anflam, Hydrocorticosterone, Hydroxycortisone, H-Cort, Hydro-Colisona, Cortisol alcohol, Incortin-hydrogen, Ala-Scalp, Aeroseb-HC, Barseb HC, Dermocortal, Nutracort, Synacort, Timocort, Evacort, Komed HC, Lacticare-HC, Texacort lotion 25, Ala-Cort, Anti-inflammatory hormone, Hydrocortisone alcohol, Hidrocortisona, Hydrocortisonum, Algicirtis, Aquacort, Cortesal, Cortisolonum, Hidalone, Hytisone, Kyypakkaus, Lactisona, Lubricort, Meusicort, Milliderm, Sanatison, Schericur, Sigmacort, Stiefcorcil, Texacort, Amberin, Cutisol, Dermil, Hydrocortisone base, Uniderm, Foille Insetti, Gyno-Cortisone, Transderma H, Basan-Corti, Clear aid, Cremicort-H, Dome-cort, Neosporin-H Ear, Remederm HC, Aquanil HC, Cortisporin Otico, Derm-Aid, Heb Cort, Scalpicin Capilar, Systral Hydrocort, Prevex HC, Cortisporin, Dermaspray, Efcortelin, Fiocortril, Hydrocortisone free alcohol, Proctofoam, Alphaderm, Colocort, Flexicort, Glycort, Hydracort, Medicort, Otocort, Zenoxone, Drotic, Vytone, 11beta-Hydroxycortisone, Balneol-hc, Stie-cort, Nystaform-HC, Beta-hc, Aeroseb HC, Nogenic HC, CaldeCORT Spray, Hi-cor, Pediotic Suspension, VoSol HC, Idrocortisone, 17alpha-Hydroxycorticosterone, Hydrocortal, Hydroskin, Otalgine, Otobiotic, Protocort, Hysone, Racet, Ef corlin, 11beta-Hydrocortisone, Compound F, Lacticare HC, Compound F (kendall), Idrocortisone [DCIT], Anusol HC, 11-beta-Hydrocortisone, Genacort (lotion), 11-beta-Hydroxycortisone, Epicortisol, Anucort, Chronocort, Cortifair, Hydrocort, Plenadren, Prepcort, Preparation H Hydrocortisone Cream, Hydrocortisonum [INN-Latin], Proctozone HC, Scalp-Cort, Hidrocortisona [INN-Spanish], Rectasol-HC, Anucort-HC, Neo-Cort-Dome, Hydro-RX, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione, HC (HYDROCORTISONE), Otic-Neo-Cort-Dome, 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione, NSC 10483, Corhydron, DuoCort, HC, Hydrocortisone (Cortisol), UNII-WI4X0X7BPJ, HYDROCORTISONE IN ABSORBASE, Neo-Cortef, HC #1, HC #4, [3H]cortisol, Acticort (TN), Colocort (TN), Prestwick_265, Cortef (TN), Hytone (TN), CCRIS 5854, component of Otalgine, Anusol HC (TN), Hydrocortisone [INN:BAN:JAN], 4-Pregnene-11beta,17alpha,21-triol-3,20-dione, component of Lubricort, CHEBI:17650, COR-OTICIN, HSDB 3339, NSC10483, 11.beta.-Hydrocortisone, EINECS 200-020-1, WI4X0X7BPJ, 11beta,17,21-Trihydroxyprogesterone, 11.beta.-Hydroxycortisone, component of Neo-Cort-Dome, ACETASOL HC, ORLEX HC, Terra-cortril, AI3-25006, MLS000069609, (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, 17.alpha.-Hydroxycorticosterone, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, JYGXADMDTFJGBT-VWUMJDOOSA-N, ACETIC ACID W/ HYDROCORTISONE, NSC-10483, Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-, SMR000059022, DSSTox_CID_714, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11-beta)-, HYDROCORTISONE AND ACETIC ACID, H 4001, CALMURID HC, DSSTox_RID_75753, 4-Pregnen-11beta,17alpha,21-triol-3,20-dione, DSSTox_GSID_20714, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, 11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11b)-, Proctosol-HC, (1S,10S,11S,15S,17S,2R,14R)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-6-en-5-one, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, 80562-38-5, SMR000653523, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-, Cortizol, (11alpha,14beta)-11,17,21-Trihydroxypregn-4-Ene-3,20-Dione, AnusolHC, 3h-cortisol, 11beta-cortisol, CAS-50-23-7, 11-Hydrocortisone, Plenadren (TN), NCGC00022848-06, 11b-Hydrocortisone, Kendalls compound F, Hydrocortisone [USP:INN:BAN:JAN], Drotic (Salt/Mix), 11b-Hydroxycortisone, Otocort (Salt/Mix), Hydrocortisone solution, Otalgine (Salt/Mix), Hydrocortisone, 98%, Alphaderm (Salt/Mix), Hydrocortisone, topical, Otobiotic (Salt/Mix), Reichsteins substance M, 4p6x, Cort-Quin (Salt/Mix), Cortisol, Hydrocortisone, Cortisporin (Salt/Mix), VoSol HC (Salt/Mix), 11a-Hydroxycorticosterone, 17a-Hydroxycorticosterone, Opera_ID_1292, Prestwick0_000447, Prestwick1_000447, Prestwick2_000447, Prestwick3_000447, D0KR5B, Epitope ID:174851, UPCMLD-DP133, EC 200-020-1, AC1L1L2B, SCHEMBL4148, Hydrocortisone, 98% 1g, Hydrocortisone-Water Soluble, Neo-Cort-Dome (Salt/Mix), Lopac0_000594, 11alpha-Hydroxycorticosterone, BSPBio_000494, MLS001148103, MLS002207135, MLS002222189, MLS002548868, SPBio_002433, BPBio1_000544, CHEMBL389621, GTPL2868, Pediotic Suspension (Salt/Mix), DTXSID7020714, UPCMLD-DP133:001, BDBM13775, CTK8F3227, Otic-Neo-Cort-Dome (Salt/Mix), 2v95, Hydrocortisone (JP15/USP/INN), Hydrocortisone (JP17/USP/INN), MolPort-001-794-637, HMS1569I16, HMS2090M04, HMS2096I16, HMS2230B18, HMS2235F17, HMS3259C05, HMS3261H10, HMS3713I16, Hydrocortisone, >=98% (HPLC), Vioform-Hydrocortisone (Salt/Mix), 11b,17,21-Trihydroxyprogesterone, BCP09054, HY-N0583, Tox21_110883, Tox21_200815, Tox21_500594, LMST02030001, MFCD00011654, s1696, SBB012589, ZINC13540519, AKOS001582651, Tox21_110883_1, CCG-204683, CS-2226, Cyclodextrin-encapsulated hydrocortisone, DB00741, LP00594, LS-7439, MCULE-8953627920, NC00456, 11.beta.,17,21-trihydroxyprogesterone, SMP1_000156, NCGC00022848-07, NCGC00022848-09, NCGC00022848-10, NCGC00022848-11, NCGC00022848-12, NCGC00022848-13, NCGC00022848-14, NCGC00022848-15, NCGC00022848-17, NCGC00258369-01, NCGC00261279-01, AC-12902, AJ-64104, AN-24370, AS-11651, BP-20390, CPD000653523, NCI60_000118, SAM002264617, SC-18577, ST069286, 4-Pregnene-11alpha,21-triol 3,20-dione, AB1009452, B1951, EU-0100594, 4-Pregnene-11b,17a,21-triol-3,20-dione, 50H237, 6861-EP2269977A2, 6861-EP2270008A1, 6861-EP2277565A2, 6861-EP2277566A2, 6861-EP2277567A1, 6861-EP2277568A2, 6861-EP2277569A2, 6861-EP2277570A2, 6861-EP2292227A2, 6861-EP2292280A1, 6861-EP2292615A1, 6861-EP2292617A1, 6861-EP2295409A1, 6861-EP2298778A1, 6861-EP2305679A1, 6861-EP2308562A2, 6861-EP2314590A1, 6861-EP2371811A2, 7062-EP2269977A2, 7062-EP2292228A1, 7062-EP2295411A1, 7062-EP2298747A1, 7062-EP2301931A1, 7062-EP2308851A1, 7062-EP2308880A1, 7062-EP2311811A1, 7062-EP2314585A1, C00735, D00088, J10114, U 1851, 92372-EP2280008A2, 92372-EP2289483A1, 92372-EP2305257A1, Hydrocortisone, meets USP testing specifications, Pregn-4-ene-3, 11.beta.,17,21-trihydroxy-, 11?,17?,21-Trihydroxypregn-4-ene-3,20-dione, Hydrocortisone, VETRANAL(TM), analytical standard, SR-01000000139, Q-201211, SR-01000000139-3, 11.beta.,17,21-Trihydroxypregn-4-ene-3,20-dione, BRD-K93568044-001-03-1, BRD-K93568044-001-11-4, BRD-K93568044-001-32-0, Hydrocortisone, BioReagent, suitable for cell culture, 4-Pregnen-11.beta.,17.alpha.,21-triol-3,20-dione, 4-Pregnene-11.beta.,17.alpha.,21-triol-3,20-dione, Pregn-4-ene-3,20-dione, 11.beta.,17,21-trihydroxy-, Z2786051549, (11beta)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione, 11.beta.,17.alpha.,21-Trihydroxy-4-pregnene-3,20-dione, 11.beta.,17.alpha.,21-Trihydroxypregn-4-ene-3,20-dione, B48448A1-24BA-47CA-8D9E-43E5BC949386, Pregn-4-ene-3, 11,17,21-trihydroxy-, (11.beta.)-, 11,17,21-Trihydroxypregn-4-ene-3,20-dione, (11.beta.)-, Hydrocortisone, European Pharmacopoeia (EP) Reference Standard, Hydrocortisone, United States Pharmacopeia (USP) Reference Standard, Hydrocortisone-Water Soluble, BioReagent, suitable for cell culture, (8xi,9xi,11beta,14xi)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Hydrocortisone, gamma-irradiated, powder, BioXtra, suitable for cell culture, 4-(6-chloro-4-oxoquinazolin-3(4H)-yl)-N-(3-methoxyphenyl)piperidine-1-carboxamide, Cortisol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Hydrocortisone for peak identification, European Pharmacopoeia (EP) Reference Standard, Hydrocortisone solution, 50 muM, sterile-filtered, BioXtra, suitable for cell culture, Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadec-6-en-5-one, 1050676-88-4, 11|A,17|A,21-Trihydroxypregn-4-ene-3,20-dione; 17-Hydroxycorticosterone; 4-Pregnene-11|A,17|A,21-triol-3,20-dione; Cortisol; Kendall inverted exclamation mark s compound F; Reichstein inverted exclamation mark s substance M, 8056-08-4, 8063-42-1


ID: 1130

chemical graph of compound 1130



InChIKey: JYJFNDQBESEHJQ-UHFFFAOYSA-N
SMILES: CC1(C(=O)NC(=O)O1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3081
synonyms found at PubChem are:
dimethadione, 5,5-Dimethyloxazolidine-2,4-dione, 695-53-4, 5,5-Dimethyl-2,4-oxazolidinedione, Dimethadion, Propazone, Eupractone, Dimethyloxazolidinedione, 2,4-Oxazolidinedione, 5,5-dimethyl-, 5,5-Dimethyl-1,3-oxazolidine-2,4-dione, BAX 1400Z, AC 1198, 5,5-Dimethyloxazolidinedione, Dimetadione [DCIT], NSC-30152, Dimethadione [USAN:INN], UNII-ALU9NPM703, Dimetadiona [INN-Spanish], Dimethadionum [INN-Latin], DMO, NSC 30152, Dimethyl-oxazolidine-2,4-dione, BAY 1400Z, EINECS 211-781-4, 5,5-Dwumetylooksazolidyno-2,4-dion, BRN 0113541, ALU9NPM703, AI3-18201, 5,5-Dwumetylooksazolidyno-2,4-dion [Polish], JYJFNDQBESEHJQ-UHFFFAOYSA-N, NSC30152, NCGC00016532-02, CAS-695-53-4, DSSTox_CID_478, 5,5-DIMETHYL OXAZOLIDINE-2,4-DIONE, 5,5-Dimethyloxazolidine-2,4-oxazolidinedione, DSSTox_RID_75614, DSSTox_GSID_20478, Dimetadiona, Dimetadione, Dimethadionum, SR-05000001609, 5,5-Dimethyl-2,4-oxazolidindion, Prestwick_55, 5,4-oxazolidinedione, PubChem8629, 5,5-Dimethyl-2,, Spectrum_000801, Trimethadion, M(nor-), AC1Q6GJV, 5,5-Dimethyl-2,4-oxazolidindion [IUPAC], Prestwick0_000829, Prestwick1_000829, Prestwick2_000829, Prestwick3_000829, Spectrum2_000108, Spectrum3_000398, Spectrum4_000518, Spectrum5_000911, Dimethadione (USAN/INN), ACMC-209o9a, AC1L1F4Q, CHEMBL1099, SCHEMBL34862, BSPBio_000757, BSPBio_002215, KBioGR_001095, KBioSS_001281, DivK1c_000939, SPECTRUM1500253, SPBio_000096, SPBio_002678, BPBio1_000833, DTXSID2020478, BAX-1400Z, CHEBI:94613, CTK8B2187, HMS502O21, KBio1_000939, KBio2_001281, KBio2_003849, KBio2_006417, KBio3_001435, KS-00000JMN, MolPort-003-666-167, NINDS_000939, WLN: T5OVMV EHJ E1 E1, HMS1570F19, HMS1920G22, HMS2091O10, HMS2097F19, HMS3714F19, Pharmakon1600-01500253, ZINC5762010, Tox21_110479, Tox21_200496, ANW-35708, CCG-38926, MFCD00005379, NSC756741, 5, 5-Dimethyloxazolidine-2,4-dione, 5,5'-Dimethyloxazolidine-2,4-dione, 5,5-Dimethyl-oxazolidine-2,4-dione, AKOS015906843, Tox21_110479_1, LS-7339, MCULE-2681916511, NSC-756741, VZ29820, IDI1_000939, 2,4-Oxazolidinedione, 5, 5-dimethyl-, NCGC00016532-01, NCGC00016532-03, NCGC00016532-04, NCGC00016532-07, NCGC00094656-01, NCGC00094656-02, NCGC00258050-01, paragraph signthorn(1/4)xE<<I feminine, AJ-54780, AN-47257, AS-14715, KB-41218, M311, SC-06324, SBI-0051352.P003, DB-055297, ST2418542, TC-124453, TL8004880, A9197, AB00051972, CS-0013093, D0003, FT-0619784, FT-0646768, ST51037235, 5,5-Dimethyl-1,3-oxazolidine-2,4-dione #, 95D534, D-5490, D03838, AB00051972_04, I14-2156, SR-05000001609-1, SR-05000001609-2, BRD-K43687498-001-02-3, F2173-0915, InChI=1/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8, 60254-97-9


ID: 1131

chemical graph of compound 1131



InChIKey: JYNZQZIFQZJCBW-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C=C1)C)NC(=O)CSC2=NN=NN2C3=CC4=C(C=C3)OCO4

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"GL Lukacs" "JM Knapp" "AS Verkman" "MJ Kurth" "PW Phuan" "AB Wood" "B Yang"


CID is 1175670
synonyms found at PubChem are:
ASN 04455937, AC1LM9VO, Oprea1_826725, ZINC932399, AKOS000690345, 2-[1-(1,3-benzodioxol-5-yl)tetrazol-5-yl]sulfanyl-N-(2,5-dimethylphenyl)acetamide


ID: 1132

chemical graph of compound 1132



InChIKey: JYTUSYBCFIZPBE-AMTLMPIISA-N
SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C(=O)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 7314
synonyms found at PubChem are:
LACTOBIONIC ACID, 96-82-2, 4-O-beta-D-Galactopyranosyl-D-gluconic acid, UNII-65R938S4DV, 4-(beta-D-Galactosido)-D-gluconic acid, CHEBI:55481, 65R938S4DV, DSSTox_CID_28787, DSSTox_RID_83056, DSSTox_GSID_48861, Lactobionicacid, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid, CAS-96-82-2, NCGC00016356-01, Prestwick_560, EINECS 202-538-3, 4-(b-d-galactosido)-d-gluconic acid, C12H22O12, Lactobionic acid, purum, Lactobionic acid, 97%, AC1L1OHJ, Prestwick0_000452, Prestwick1_000452, Prestwick2_000452, Prestwick3_000452, AC1Q5R2L, AC1Q77QA, SCHEMBL24870, BSPBio_000524, SPBio_002463, BPBio1_000578, CHEMBL3039602, DTXSID3048861, KS-00000VVK, JYTUSYBCFIZPBE-AMTLMPIISA-N, MolPort-001-793-061, s190, HMS1569K06, HMS2096K06, ZINC4215172, 96-82-2, cGMP, Methyl (R)-(-)-2-Chloromandelate, Tox21_113353, CG-043, GC3782, MFCD00078147, AKOS015896798, AKOS015924795, Tox21_113353_1, API0003109, CCG-214227, EBD2197418, Lactobionic acid, cell impermeant agent, NCGC00179532-01, NCGC00179532-03, 4-O-beta-galactopyranosyl-d-gluconic acid, 5001-51-4 (calcium salt[2:1]), AK209011, AN-42816, AS-16070, KB-78078, SC-97018, 4-O-?-D-Galactopyranosyl-D-gluconic acid, 4-O-|A-D-Galactopyranosyl-D-gluconic acid, AB0018521, FT-0657775, L0005, S-1119, 078L147, I07-0131, D0229170-C0EC-40FC-A777-BF34018EED2A, Lactobionic acid, European Pharmacopoeia (EP) Reference Standard, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)hexanoic acid, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid, 2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid


ID: 1133

chemical graph of compound 1133



InChIKey: JYVXNLLUYHCIIH-ZCFIWIBFSA-N
SMILES: C[C@]1(CCOC(=O)C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6419891
synonyms found at PubChem are:
19115-49-2, (R)-(-)-Mevalonolactone, (-)-Mevalonolactone, UNII-661X270Z3L, (R)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one, Mevalonic-D, L acid lactone, (R)-(-)-3-Hydroxy-3-methyl-5-pentanolide, CHEBI:67849, 661X270Z3L, M-6701, Adeka mevalonolactone, (3R)-Mevalonolactone, Mevalonolactone, (-)-, r-mevalonolactone, (-)-(R)-Mevalonic acid lactone, Prestwick_97, (R)-Mevalolactone, R(-)Mevalonolactone, AC1O4WFW, D-Mevalonic Acid Lactone, Prestwick0_000750, Prestwick1_000750, Prestwick2_000750, SCHEMBL879, R-mevalonolactone, (-)-, SPBio_002679, 2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-, CHEMBL1401520, 2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-, JYVXNLLUYHCIIH-ZCFIWIBFSA-N, HMS1570E22, ZINC4202723, (4R)-4-hydroxy-4-methyloxan-2-one, AKOS017343730, FCH3612269, (R)-3-hydroxy-3-methyl-5-pentanolide, NCGC00016531-01, AJ-48485, CAS-674-26-0, KB-03244, (R)-3-Hydroxy-3-methyl-|A-valerolactone, DB-044755, FT-0637792, (R)-(-)-Mevalonolactone, >=90.0% (GC), C-01262, I14-86004, UNII-1RJ06DC41B component JYVXNLLUYHCIIH-ZCFIWIBFSA-N


ID: 1134

chemical graph of compound 1134



InChIKey: JZFPYUNJRRFVQU-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4488
synonyms found at PubChem are:
niflumic acid, 4394-00-7, Nifluril, Landruma, Forenol, Actol, Acido niflumico, Nifluminic acid, Acide niflumique, Acidum niflumicum, Acide niflumique [INN-French], Acido niflumico [INN-Spanish], Acidum niflumicum [INN-Latin], Donalgin, Niflumate, 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid, Acide niflumique [French], Acido niflumico [Italian], UP 83, 2-(3-(Trifluoromethyl)-phenyl)aminonicotinic acid, 2-(3-(Trifluoromethyl)anilino)nicotinic acid, 2-[3-(Trifluoromethyl)anilino]nicotinic acid, Niflamol, Niflam, Lopac-N-0630, 2-(3-Trifluoromethylanilino)nicotinic Acid, UNII-4U5MP5IUD8, Niflumic acid [INN:DCF], Niflugel (TN), SC 1332, CCRIS 5740, 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, Niflumic acid (INN), 2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid, 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid, EINECS 224-516-2, 2-(3-Trifluoromethyl-phenylamino)-nicotinic acid, BRN 0489360, 4U5MP5IUD8, MLS000069713, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, NFL, CHEBI:34888, 3-Pyridinecarboxylic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino [French], JZFPYUNJRRFVQU-UHFFFAOYSA-N, 2-[(3-TRIFLUOROMETHYL)PHENYL]AMINO-3-PYRIDINE-CARBOXYLIC ACID, 2-((3-(Trifluoromethyl)phenyl)amino)nicotinic acid, Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino, 2-[alpha,alpha,alpha-trifluoro-m-toluidino]-nicotinic acid, NCGC00015724-10, SMR000058199, CAS-4394-00-7, DSSTox_CID_3368, 2-(3-[Trifluoromethyl]anilino)nicotinic acid, N 0630, DSSTox_RID_76996, 2-(3-(Trifluoromethyl)phenylamino)nicotinic acid, 2-[(3-Trifluoromethylphenyl)amino]nicotinic Acid, DSSTox_GSID_23368, 2-[(3-Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid, Nicotinic acid, 2-(alpha,alpha,alpha-trifluoro-m-toluidino)-, Niflactol, Niflugel, Flunir, Acid, Niflumic, SR-01000000231, 2-[[3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid, NiflumicAcid, ni-flumic acid, Niflumic acid [INN:BAN:DCF], Actol, analgesic, Prestwick_890, PubChem21796, Spectrum_001353, 1td7, ACMC-209jvx, Opera_ID_1746, Prestwick0_000255, Prestwick1_000255, Prestwick2_000255, Prestwick3_000255, Spectrum2_000794, Spectrum3_001485, Spectrum4_000043, Spectrum5_001216, Niflumic acid (Hit 16), D00HGB, AC1L1IA4, CBiol_001828, Lopac0_000845, SCHEMBL24706, BSPBio_000070, BSPBio_001393, BSPBio_003069, KBioGR_000113, KBioGR_000505, KBioSS_000113, KBioSS_001833, 5-22-13-00598 (Beilstein Handbook Reference), KSC587Q8N, MLS001076327, CHEMBL63323, DivK1c_000277, SPECTRUM1502015, SPBio_000928, SPBio_002289, BPBio1_000078, GTPL2439, DTXSID1023368, UPSA Brand 1 of Niflumic Acid, UPSA Brand 2 of Niflumic Acid, BDBM85507, CTK4I7886, HMS500N19, KBio1_000277, KBio2_000113, KBio2_001833, KBio2_002681, KBio2_004401, KBio2_005249, KBio2_006969, KBio3_000225, KBio3_000226, KBio3_002569, MolPort-000-140-647, NINDS_000277, Upsamedica Brand of Niflumic Acid, Bio1_000114, Bio1_000603, Bio1_001092, Bio2_000113, Bio2_000593, HMS1361F15, HMS1568D12, HMS1791F15, HMS1921D12, HMS1989F15, HMS2090D19, HMS2095D12, HMS2234F11, HMS3262J11, HMS3374H01, HMS3402F15, HMS3649A08, HMS3656P14, HMS3712D12, Pharmakon1600-01502015, UP-83, ZINC125031, HY-B0493, KS-00000CB5, NSC_4488, Tox21_110206, Tox21_500845, ANW-30043, BBL003619, CCG-40157, DL-457, MFCD00010569, Nicotinic acid, 2-(.alpha.,.alpha.,.alpha.-trifluoro-m-toluidino)-, NSC758196, s3018, SBB001146, STK803109, UPSA Conseil Brand of Niflumic Acid, AKOS000519590, Tox21_110206_1, AC-2652, CS-2614, DB04552, GS-3202, LP00845, MCULE-3027710274, NSC-758196, RTR-017015, IDI1_000277, IDI1_033863, NCGC00015724-01, NCGC00015724-02, NCGC00015724-03, NCGC00015724-04, NCGC00015724-05, NCGC00015724-06, NCGC00015724-07, NCGC00015724-08, NCGC00015724-09, NCGC00015724-11, NCGC00015724-12, NCGC00015724-13, NCGC00015724-14, NCGC00015724-17, NCGC00023636-03, NCGC00023636-04, NCGC00023636-05, NCGC00023636-06, NCGC00023636-07, NCGC00023636-08, NCGC00023636-09, NCGC00261530-01, AJ-11904, AN-13743, BAS 00821161, BC218927, BR-72979, LS-96639, ST013871, CAS_4394-00-7, SBI-0050821.P003, 2(3'-trifluormethylanilino)-nicotinic acid, AB0012229, AB1004097, 2-(3-(Trifluoromethyl)anilino)nicotinicacid, AB00052255, AM20070143, EU-0100845, FT-0603659, ST24027408, T7852, 2-(A,A,A-Trifluoro-m-toluidino)nicotinic acid, 39690A, C13698, D08275, S00109, AB00052255-17, AB00052255_18, AB00052255_19, 394N007, SR-01000000231-2, SR-01000000231-5, SR-01000000231-6, W-106215, BRD-K98763141-001-04-3, BRD-K98763141-001-06-8, BRD-K98763141-001-17-5, SR-01000000231-11, 2-[3-(Trifluoromethyl)anilino]-3-pyridinecarboxylic acid, Niflumic acid, European Pharmacopoeia (EP) Reference Standard, 2-{[3-(trifluoromethyl)-phenyl]-amino}-3-pyridincarboxylic acid, 2-[3-(Trifluoromethyl)anilino]nicotinic acid; 2-(|A,|A,|A-Trifluoro-m-toluidino)nicotinic acid


ID: 1135

chemical graph of compound 1135



InChIKey: JZNBMCOSOXIZJB-UHFFFAOYSA-N
SMILES: CC(CCCC(C)(C)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 10969
synonyms found at PubChem are:
Heptaminol hydrochloride, 543-15-7, Cardiosintol, 6-Amino-2-methyl-2-heptanol hydrochloride, Coreptil, Cortensor, Delmiton, Arcor tropfen, Heptamyl tropfen, Heptylon tropfen, Heptaminol HCl, Heptaminol (hydrochloride), Hept-a-myl tropfen, Heptamyl hydrochloride, 2-Methyl-6-amino-2-heptanol hydrochloride, EA-85, EINECS 208-837-5, 6-amino-2-methylheptan-2-ol hydrochloride, 6-Methyl-2-amino-6-heptanol hydrochloride, R.P. 2831, 2-Heptylamine, 6-hydroxy-6-methyl-, hydrochloride, 2-HEPTANOL, 6-AMINO-2-METHYL-, HYDROCHLORIDE, NCGC00095021-01, 6-Hydroxy-6-methyl-2-heptylamine Hydrochloride, DSSTox_CID_25891, DSSTox_RID_81205, DSSTox_GSID_45891, Corasor, Heptylon, Isoktamil, Izoktamil, Respirin, Eoden, SR-01000872644, Prestwick_257, Heptaminolhydrochlorid, Hept-a-myl (TN), Corasore Hydrochloride, AC1L1WCB, C8H19NO.HCl, CAS-543-15-7, SCHEMBL317122, SPECTRUM1503218, 372-66-7 (Parent), CHEMBL2107282, DTXSID9045891, CTK8J1533, JZNBMCOSOXIZJB-UHFFFAOYSA-N, MolPort-003-666-458, HMS1568C11, HMS1922I21, Pharmakon1600-01503218, HY-B1231, Tox21_111391, CCG-39314, NSC758406, SBB003737, AKOS024348835, Tox21_111391_1, CHM0034847, CS-4878, MCULE-8595786566, NSC-758406, 6-amino-2-methylheptan-2-ol, chloride, NCGC00095021-02, NCGC00178043-05, CC-22425, LS-74420, 6-amino-2-methylheptan-2-ol;hydrochloride, DB-052535, KB-199018, FT-0669129, ST50825179, 6-Hydroxy-6-methyl-2-heptamine Hydrochloride, D08038, 2-Amino-6-hydroxy-6-methylheptane Hydrochloride, 6-AMINO-2-METHYL-2-HEPTANOLHYDROCHLORIDE, 6-Hydroxy-6-methyl-2-aminoheptane Hydrochloride, (5-Hydroxy-1,5-dimethylhexyl)amine Hydrochloride, C-06888, SR-01000872644-1, SR-01000872644-2, Heptaminol hydrochloride, European Pharmacopoeia (EP) Reference Standard, 53572-44-4, AKOS026749772


ID: 1136

chemical graph of compound 1136



InChIKey: JZQKKSLKJUAGIC-NSHDSACASA-N
SMILES: CC(C)NC[C@@H](COC1=CC=CC2=C1C=CN2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 688095
synonyms found at PubChem are:
S(-)-Pindolol, (S)-(-)-pindolol, 26328-11-0, (S)-pindolol, (-)-pindolol, S(?)-Pindolol, CHEMBL117405, CHEBI:48281, (2S)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, (2S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol, (2S)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol, (S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, (2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol, SR-01000075488, espindolol, S-(-)-Pindolol, AC1LELBQ, Tocris-1060, S(-)-Pindolol, solid, SCHEMBL5220, Lopac0_000349, Lopac0_001027, GTPL127, MLS001056774, mt-102, CTK8F2100, ZINC56645, MolPort-003-959-160, HMS2231C09, HMS3261E19, HMS3267E06, Tox21_500349, 2-Propanal, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, (S)-, BDBM50072755, PDSP1_000743, PDSP2_000731, AKOS024456358, API0005632, CCG-204444, LP00349, ACM26328110, NCGC00024973-01, NCGC00024973-02, NCGC00024973-03, NCGC00024973-04, NCGC00024973-05, NCGC00261034-01, SMR000326991, KB-267891, B6575, EU-0100349, EU-0101027, P-152, 328P110, SR-01000597475, J-016382, SR-01000075488-1, SR-01000075488-2, SR-01000597475-1, BRD-K95598440-001-03-6, UNII-BJ4HF6IU1D component JZQKKSLKJUAGIC-NSHDSACASA-N, 2-Propanal,1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-,(S)-, 2-propanol,1-(1h-indol-4-yloxy)-3-[(1-methylethyl)amino]-,(2s)-


ID: 1137

chemical graph of compound 1137



InChIKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=CC2=C1C=CN2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4828
synonyms found at PubChem are:
pindolol, Prinodolol, Visken, Betapindol, 13523-86-9, Carvisken, Durapindol, Pinbetol, Calvisken, Decreten, Pectobloc, Pynastin, Blocklin L, Pindololum, LB-46, Glauco-visken, Glauco-Viskin, Blockin L, LB 46, Prindolol, (+-)-Pindolol, Blocklin-L, DL-Pindolol, Pindololum [INN-Latin], 4-(2-Hydroxy-3-isopropylaminopropoxy)-indole, Blocklin, 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, Carvisken (TN), 4-(3-(Isopropylamino)-2-hydroxypropoxy)indole, Blocklin-L (TN), Visken (TN), CCRIS 9215, HSDB 6539, Pindolol [USAN:INN:BAN:JAN], 1-((1-Methylethyl)amino)-3-(4-indolyloxy)-2-propanol, EINECS 236-867-9, EINECS 244-623-8, 1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol, 2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, 2-Propanol, 1-(4-indolyloxy)-3-(isopropylamino)-, BRN 1536506, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol, CHEBI:8214, DL-LB 46, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol, 2-Propanol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, JZQKKSLKJUAGIC-UHFFFAOYSA-N, P-6820, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, NCGC00015786-11, (1)-1-(1H-Indol-4-yloxy)-3-(isopropylamino)propan-2-ol, DSSTox_CID_3476, P 0778, DSSTox_RID_77043, DSSTox_GSID_23476, DL-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole, 1-((1H-indol-4-yl)oxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol, 1-[1H-INDOL-4-YLOXY]-3-[ISOPROPYLAMINO]-2-PROPANOL, 2-Propanol, 1-(1H-indol-4-yloxy)-3-(1-methylethyl)amino-, 2-Propanol, 1-(indol-4-yloxy)-3-(isopropylamino)-, (+-)-, SMR000059120, SR-01000000027, LB46, (rs)-pindolol, Betapindol (TN), Durapindol (TN), Calvisken (TN), Pectobloc (TN), Prindolol (TN), Decreten (TN), Pinbetol (TN), Pynastin (TN), Prestwick_397, Blocklin L (TN), CAS-13523-86-9, Blockin L (TN), Pindolol [USAN:USP:INN:BAN:JAN], Glauco-Visken (TN), Spectrum_001109, (.+/-.)-Pindolol, Prestwick0_000090, Prestwick1_000090, Prestwick2_000090, Prestwick3_000090, Spectrum2_001285, Spectrum3_000547, Spectrum4_000479, Spectrum5_001266, (R,S)-PINDOLOL, CHEMBL500, D0F2PO, GTPL91, PINDOLOL,(-), AC1L1J1N, AC1Q1QC1, SCHEMBL5219, Lopac0_000955, Oprea1_770884, BSPBio_000020, BSPBio_002193, KBioGR_000958, KBioSS_001589, 5-21-03-00017 (Beilstein Handbook Reference), MLS000069496, MLS002548891, DivK1c_000837, SPECTRUM1500488, Pindolol (JP15/USP/INN), Pindolol (JP17/USP/INN), SPBio_001289, SPBio_001959, BPBio1_000022, DTXSID8023476, CTK8G2432, HMS502J19, KBio1_000837, KBio2_001589, KBio2_004157, KBio2_006725, KBio3_001693, MolPort-001-792-503, NINDS_000837, HMS1568A22, HMS1920H16, HMS2089I21, HMS2091P20, HMS2095A22, HMS3259I07, HMS3262P12, HMS3267K17, HMS3369E14, HMS3712A22, Pharmakon1600-01500488, (+-)-lb46, HY-B0982, Pindolol, >=98% (TLC), powder, Tox21_110221, Tox21_500955, BDBM50019443, BG0392, CCG-39223, MFCD00010530, NSC757276, PDSP1_000771, PDSP1_000772, PDSP2_000759, PDSP2_000760, (+/-)-Pindolol-d7(iso-propyl-d7), AKOS015969756, Tox21_110221_1, API0000920, CS-4473, DB00960, LP00955, MCULE-7764948919, NC00467, NSC-757276, IDI1_000837, NCGC00015786-06, NCGC00015786-07, NCGC00015786-08, NCGC00015786-09, NCGC00015786-10, NCGC00015786-13, NCGC00015786-14, NCGC00015786-16, NCGC00015786-20, NCGC00024925-03, NCGC00024925-04, NCGC00024925-05, NCGC00024925-06, NCGC00024925-07, NCGC00261640-01, AN-18448, CC-33796, CPD000059120, SAM002264631, SC-25688, SBI-0050929.P004, LS-122385, AB00052072, EU-0100955, FT-0630406, ST50319990, Z3376, C07445, D00513, AB00052072-11, AB00052072_12, AB00052072_13, 1-(4-Indolyloxy)-3-(isopropylamino)-2-propanol, 523P869, C-15218, L000006, 3-indol-4-yloxy-1-[(methylethyl)amino]propan-2-ol, SR-01000000027-2, SR-01000000027-4, SR-01000000027-5, SR-01000000027-7, (+-)-4-(2-hydroxy-3-(isopropylamino)propoxy)indole, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol, BRD-A97701745-001-05-3, BRD-A97701745-001-09-5, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol #, Pindolol, European Pharmacopoeia (EP) Reference Standard, [2-hydroxy-3-(1H-indol-4-yloxy)propyl](propan-2-yl)amine, 1-(1h-indol-4-yloxy)-3-((1-methylethyl)amino)-2-propano, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol), Pindolol, United States Pharmacopeia (USP) Reference Standard, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol), 21870-06-4


ID: 1138

chemical graph of compound 1138



InChIKey: JZUFKLXOESDKRF-UHFFFAOYSA-N
SMILES: C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3639
synonyms found at PubChem are:
hydrochlorothiazide, 58-93-5, Hypothiazide, Esidrix, HCTZ, Oretic, Dichlotiazid, Hidrotiazida, Hydrochlorothiazid, Hydrochlorthiazide, Hydrodiuretic, Hydrosaluric, Servithiazid, Aquarills, Aquarius, Dichlotride, Diclotride, Disalunil, Hypothiazid, Idrotiazide, Maschitt, Megadiuril, Newtolide, Thiuretic, Vetidrex, Drenol, Esidrex, Hidril, Hydril, Nefrix, Chlorosulthiadil, Hidrochlortiazid, Hydro-Diuril, Hydro-Aquil, Dihydrochlorothiazide, Jen-Diril, HydroDIURIL, Dihydrochlorothiazid, Dihydrochlorothiazidum, Apresazide, Carozide, Chlorzide, Dichlorosal, Hidroronol, Hydrothide, Hydrozide, Moduretic, Neoflumen, Urodiazin, Bremil, Cidrex, Direma, Dyazide, Fluvin, Ivaugan, Panurin, Ro-hydrazide, Neo-codema, Acuretic, Caplaril, Hydrocot, Microzide, Thlaretic, Timolide, Diaqua, Aquazide H, Lotensin HCT, 3,4-Dihydrochlorothiazide, Aldoril, Hydropres, Thiaretic, Vaseretic, Ziac, Zide, Diu-melusin, Apo-Hydro, Lopressor HCT, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Hydro-D, Hydrochlorothiazidum, Dichlothiazide, Hidrosaluretil, Acesistem, Aldazida, Briazide, Catiazida, Chlorizide, Chlothia, Condiuren, Dihydran, Disothiazid, Diurogen, Dixidrasi, Esoidrina, Hyclosid, Indroclor, Medozide, Mikorten, Modurcen, Natrinax, Novodiurex, Pantemon, Saldiuril, Selozide, Spironazide, Acuilix, Clorana, Didral, Hytrid, Manuril, Mictrin, Nefrol, Roxane, Tandiur, Unazid, Urozide, Dihydrochlorurit, Hidro-Niagrin, Hydro-Saluric, Dihydrochlorurite, Hidroclorotiazida, Raunova Plus, Concor Plus, Aquazide-H, Neo-Flumen, Neo-Minzil, Hydro Par, Hydro-T, Hydrochlorthiazidum, HCT-Isis, Su 5879, Mazide 25 mg, Hydrochlorat, Hydrochlorot, Prinzide, Sectrazide, Hydrochlorothiazide Intensol, Idroclorotiazide, Diu 25 Vigt, Hydrex-semi, Aldactazide 25/25, Aldectazide 50/50, Dihydroxychlorothiazidum, Inderide 80/25, NCI-C55925, Idroclorotiazide [DCIT], component of Cyclex, component of Esimil, Esidrix (TN), Ser-Ap-Es, component of Aldoril, component of Dyazide, component of Caplaril, HCZ, Chlorsulfonamidodihydrobenzothiadiazine dioxide, Dichlorotride, Dicyclotride, Hydrochlorzide, component of Aldactazide, Hydrozide Injection, Veterinary, diclot ride, Ezide, Hidroclorotiazida [INN-Spanish], Hydro-chlor, Hydrochlorothiazidum [INN-Latin], panurin dichloride, UNII-0J48LPH2TH, C7H8ClN3O4S2, Microzide (TN), component of Butizide Prestabs, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, CCRIS 2082, HSDB 3096, Hydrochlorothiazide [INN:BAN:JAN], EINECS 200-403-3, NSC 53477, BRN 0625101, 0J48LPH2TH, 6-Chloro-3,4-dihydro-(2H)-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide, MLS000069619, CHEBI:5778, H.H. 25/25, H.H. 50/50, JZUFKLXOESDKRF-UHFFFAOYSA-N, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, NSC53477, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, HCT, CAS-58-93-5, NCGC00015508-08, SMR000035778, DSSTox_CID_713, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1, 1-dioxide, 6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, H 4759, DSSTox_RID_75752, DSSTox_GSID_20713, AF-614/30832002, Q-201210, 3,4-dihydro-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, SR-01000000119, Hydrokraft, Idrodiuvis, Manschitt, Urirex, HydroPar, 6-chloro-1,1-dioxo-2H,3H,4H-benzo[e]1,2,4-thiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Dichlotride (TN), Hydrodiuril (TN), Prestwick_263, Esidrex (TN), Hydrochloro Thiazide, HydroSaluric (TN), Aquazide H (TN), Hyzaar (Salt/Mix), Oretic (TN), Apo-Hydro (TN), Aldoril (Salt/Mix), MaybridgeCompound 10, Dutoprol (Salt/Mix), Inderide (Salt/Mix), Prinzide (Salt/Mix), adiazine-1,1-dioxide, Accuretic (Salt/Mix), Hydropres (Salt/Mix), Thiazide, hydrochloro-, Hydrochlorothiazide [USP:INN:BAN:JAN], Spectrum_000877, Opera_ID_168, AC1L1GDT, Maybridge1_004336, Prestwick0_000009, Prestwick1_000009, Prestwick2_000009, Prestwick3_000009, Spectrum2_001040, Spectrum3_000456, Spectrum4_000006, Spectrum5_000824, Lopac-H-4759, CHEMBL435, D0U4UQ, Tekturna HCT (Salt/Mix), AC1Q55FM, cid_3639, SCHEMBL9349, Lopac0_000614, Oprea1_357174, BSPBio_000017, BSPBio_002132, KBioGR_000351, KBioSS_001357, KSC492I2H, ARONIS24316, BIDD:GT0153, DivK1c_000289, SPECTRUM1500335, BMCL182567 Compound 6a, SPBio_001259, SPBio_001938, BPBio1_000019, GTPL4836, Hydrochlorothiazide, 98% 5g, Hydrochlorothiazide, crystalline, DTXSID2020713, BDBM13076, component of Dyazide (Salt/Mix), CTK3J2423, HMS500O11, HMS553N04, KBio1_000289, KBio2_001357, KBio2_003925, KBio2_006493, KBio3_001352, KS-00000VPM, BBC/472, component of Caplaril (Salt/Mix), MolPort-000-144-465, NINDS_000289, HMS1568A19, HMS1920D19, HMS2091L05, HMS2095A19, HMS2235I09, HMS3259O17, HMS3261L10, HMS3370P11, HMS3428A05, HMS3655M21, HMS3712A19, Pharmakon1600-01500335, ZINC896569, 6-Chloro-7-sulfamoyl-3, 4-dihy, BCP22001, EBD18905, HY-B0252, JFD00715, ZX-AS004676, ZX-AT004440, Tox21_110165, Tox21_201565, Tox21_300292, Tox21_500614, BG0215, CCG-40240, IMED56428485, LS-243, MFCD00051765, NSC-53477, NSC757059, OR0507, s1708, SBB056984, STK315354, 3,2,4-benzothiadiazine-1,1-dioxide, Hydrochlorothiazide (JP15/USP/INN), Hydrochlorothiazide (JP17/USP/INN), AKOS000121373, Tox21_110165_1, AC-8114, AN-8344, API0002941, CS-2232, DB00999, LP00614, MCULE-6585933943, NC00510, NSC-757059, PS-3162, IDI1_000289, KS-0000477T, WLN: T66 BSWM EM DHJ HG ISZW, NCGC00015508-01, NCGC00015508-02, NCGC00015508-03, NCGC00015508-04, NCGC00015508-05, NCGC00015508-06, NCGC00015508-07, NCGC00015508-09, NCGC00015508-10, NCGC00015508-11, NCGC00015508-12, NCGC00015508-13, NCGC00015508-14, NCGC00015508-16, NCGC00015508-17, NCGC00021906-03, NCGC00021906-04, NCGC00021906-05, NCGC00021906-06, NCGC00021906-07, NCGC00021906-08, NCGC00254017-01, NCGC00259114-01, NCGC00261299-01, BAS 00371709, CJ-04492, CPD000035778, NCI60_004317, SAM002554901, SC-16312, SC-60934, ST033548, component of Butizide Prestabs (Salt/Mix), Hydrochlorothiazide 1.0 mg/ml in Methanol, SBI-0050596.P004, AB1009416, KB-199316, RT-000622, AB00052012, EU-0100614, FT-0082750, FT-0650564, dro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-3,2,4-benzothiadiazine 1,1-dioxide, A19550, C07041, D00340, J10079, AB00052012-15, AB00052012_16, AB00052012_17, BENZENEETHANIMIDAMIDE,3-CHLORO-N-HYDROXY-, 051H765, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi, Hydrochlorothiazide, meets USP testing specifications, I09-0531, SR-01000000119-2, SR-01000000119-4, SR-01000000119-6, BRD-K13078532-001-05-2, Z56347248, 6-Chloro-3,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,2,4-benzothiadiazine 1,1-dioxide, Hydrochlorothiazide, drug standard, 1.0 mg/mL in methanol, 6-chloro-3,4-dihydro-1,1-dioxo-7-sulfamoyl-1,2,4-benzothiadiazine, Hydrochlorothiazide, European Pharmacopoeia (EP) Reference Standard, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothiadiazine-1,1-dioxide, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, 6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulphonamide-1,1-dioxide, 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2, 4-benzothiadiazine 1,1-dioxide, 6-chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-7-sulfamoyl-3, 4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-Dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, Hydrochlorothiazide, United States Pharmacopeia (USP) Reference Standard, 2H-1,2, 4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1, 1-dioxide, 2H-1,2,4-Benzothiadiazine, 6-chloro-3,4-dihydro-7-sulfamoyl-2, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-,1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, 6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1, 1-dioxide, 7-(Aminosulfonyl)-6-chloro-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-Dioxide, Hydrochlorothiazide for peak identification, European Pharmacopoeia (EP) Reference Standard, Hydrochlorothiazide, Pharmaceutical Secondary Standard; Certified Reference Material, 125727-50-6, 3,4-Dihydro-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide; 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide; 3,4-Dihydrochlorothiazide, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 8049-49-8


ID: 1139

chemical graph of compound 1139



InChIKey: KAHMEWANVDFFCQ-UHFFFAOYSA-N
SMILES: COC1=C(C(=CC=C1)OC)OCCNCC2COC3=CC=CC=C3O2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11957505
synonyms found at PubChem are:
WB 4101 hydrochloride, WB-4101 hydrochloride, WB4101 hydrochloride, 2170-58-3, CHEBI:64094, N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride, 2-(2,6-Dimethoxyphenoxyethyl)aminomethyl-1,4-benzodioxane hydrochloride, N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride, MLS000859914, 2- (2,6-DIMETHOXYPHENOXYETHYL)AMINOMETHYL-1,4-BENZODIOXANE HYDROCHLORIDE (WB 4101), N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanaminium chloride, SR-01000075254, SMR000326775, (2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)[2-(2,6-dimethoxyphenoxy)ethyl]ammonium chloride, EU-0100335, SCHEMBL989002, SPECTRUM1503647, CHEMBL556001, DTXSID2042565, CTK8G3780, MolPort-003-666-495, Tox21_500335, BN0543, CCG-39353, AKOS024458707, LP00335, NCGC00093775-01, NCGC00093775-02, NCGC00093775-03, NCGC00261020-01, LS-33979, KB-220648, WB-4101 hydrochloride, analytical standard, D 0411, J-014246, SR-01000075254-1, SR-01000075254-3


ID: 1140

chemical graph of compound 1140



InChIKey: KBAUFVUYFNWQFM-UHFFFAOYSA-N
SMILES: CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11224
synonyms found at PubChem are:
Doxylamine succinate, 562-10-7, Decapryn, Doxylamine (succinate), Evigoa D, A-H Injection, Decapryn Succinate, Doxylamine succinate salt, Unisom, Alsadorm, Gittalun, Mereprine, Sedaplus, Doxy-sleep-aid, Doxylamine succinate (1:1), Hoggar N, Decapryn succinate (1:1), Doxylamine hydrogen succinate, CCRIS 4811, EINECS 209-228-7, NSC 74772, Doxylamine succinate [USP], AI3-23993, MLS000028417, 2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate (1:1), CHEBI:82461, Dimethylaminoethoxy-methyl-benzyl-pyridine succinate, 2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate, SMR000058436, Decapryn (TN), DSSTox_CID_552, Phenyl2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether succinate, 2-(alpha-(2-Dimethylaminoethoxy)-alpha-methylbenzyl)pyridine succinate, Doxylamine-d5 Succinate, 2-(alpha(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine succinate (1:1), Doxylamine succinate (USP), alpha-(2-Dimethylaminoethoxy)-alpha-methyl-alpha-phenyl-2-picoline acid succinate, Butanedioic acid, compd. with N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine (1:1), Butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1), DSSTox_RID_75656, DSSTox_GSID_20552, C21H28N2O5, N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine succinate, N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine succinate, N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethenamine succinate, Topcare sleep aid, Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, butanedioate (1:1), Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1), SR-01000003036, EQUALINE SLEEP AID, Doxylamine succinate liquid, Decarpyn succinate (1:1), Safetussin, N,N-dimethyl-2-[1-phenyl-1-pyridin-2-ylethoxy]ethanamine succinate, butanedioic acid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, C17H22N2O.C4H6O4, NCGC00017028-02, CAS-562-10-7, Prestwick_887, Opera_ID_566, doxylamine; succinic acid, AC1L1WW1, AC1Q5VR4, Pyridine, succinate (1:1), MLS000758288, MLS001076141, MLS001424137, MLS002222274, SCHEMBL160443, SPECTRUM1500267, CHEMBL1200392, DTXSID7020552, HMS502K03, MolPort-003-666-172, HMS1568E15, HMS1920K04, HMS2051F14, HMS2091B09, HMS2095E15, HMS2231G05, HMS3261E17, HMS3370K04, HMS3393F14, HMS3652H19, HMS3712E15, Pharmakon1600-01500267, BCP24067, HY-A0069, NSC74772, Tox21_113515, Tox21_202078, Tox21_302861, Tox21_500348, BG0679, CCG-38929, MFCD00056168, NSC-74772, NSC756752, s4240, AKOS025310916, Tox21_113515_1, AC-4487, API0002494, CCG-101033, CS-3232, LP00348, LS-1380, NC00283, NSC-756752, NCGC00016140-02, NCGC00016140-03, NCGC00016140-04, NCGC00021147-11, NCGC00089789-03, NCGC00093785-01, NCGC00093785-02, NCGC00093785-03, NCGC00256517-01, NCGC00259627-01, NCGC00261033-01, AN-11902, AS-13661, BC678008, CPD000058436, Q835, SAM001247030, ACM1216840946, AB0017830, KB-295989, EU-0100348, FT-0082833, FT-0625595, WLN: T6NJ BX1&R&O2N1&1 &OV2VO, C19414, D 3775, D-9200, D02327, J10070, SR-01000003036-2, SR-01000003036-6, SR-01000003036-9, (Dimethylamino)ethoxy-methyl-benzyl-pyridine succinate, F2173-1155, [[[(2-Dimethylamino)ethoxy]phenyl]methyl]-2-picoline succinate, 2-[a-[2-(Dimethylamino)ethoxy]-a-methylbenzyl]pyridine succinate, Doxylamine Hydrogen Succinate 1.0 mg/ml in Methanol (as free base), butanedioic acid,N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, butanedioic acid; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, Doxylamine succinate, United States Pharmacopeia (USP) Reference Standard, n,n-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine butanedioate, N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine; succinic acid, Phenyl2-pyridylmethyl-(.beta.-N,N-dimethylamino)ethyl ether succinate, 2-[[.alpha.-(2-Dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine succinate, Butanedioic acid,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1), Doxylamine for system suitability, European Pharmacopoeia (EP) Reference Standard, Doxylamine hydrogen succinate, European Pharmacopoeia (EP) Reference Standard, Doxylamine Succinate, Pharmaceutical Secondary Standard; Certified Reference Material, 121367-03-1, Succinic acid, compd. with 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine (1:1), Succinic acid, compd. with 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine (1:1) (8CI), Succinic acid, compd. with 2-[.alpha.-[2-(dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine (1:1), dimethyl[2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl]amine, butanedioic acid, SBB057413, AKOS024366248, MCULE-7394342520, ST50999670


ID: 1141

chemical graph of compound 1141



InChIKey: KBDSLGBFQAGHBE-MSGMIQHVSA-N
SMILES: C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 179651
synonyms found at PubChem are:
Limonin, 1180-71-8, Dictamnolactone, Obaculactone, Citrolimonin, Evodin, Limonine, 7,16-Dioxo-7,16-dideoxylimondiol, Limoni, Limonoic acid, di-delta-lactone, UNII-L0F260866S, NSC 36508, Limonoate D-ring-lactone, CHEBI:16226, L0F260866S, Limonoic acid 3,19:16,17 dilactone, limonoic acid 3,19:16,17-dilactone, DSSTox_CID_25985, DSSTox_RID_81273, DSSTox_GSID_45985, limonoic acid di-delta-lactone, Evodia fruit, (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)-12-(3-furyl)-6,6,8a,12a-tetramethyldecahydro-3H-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione, (4aS,6aR,8aR,8bR,9aS,12S,12aS,14aR,14bR)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-1H,3H-oxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione, CAS-1180-71-8, AI3-37932, 3-furyl(tetramethyl)[?]trione, NSC36508, CCRIS 4047, NCGC00095714-01, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-, Spectrum2_001728, Spectrum3_001012, Spectrum4_001140, Spectrum5_000935, AC1L45NQ, Limonin, analytical standard, BSPBio_002763, KBioGR_001659, Limonoic acid di-del.-lactone, SCHEMBL320315, SPECTRUM1800018, SPBio_001776, CHEMBL517449, DTXSID8045985, ACon1_001996, KBio3_001983, Limonoic acid di-.delta.-lactone, KBDSLGBFQAGHBE-MSGMIQHVSA-N, MolPort-001-742-490, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR-(2aalpha,4abeta,4bR,5aalpha,8alpha,8aalpha,10aalpha,10bR*,14aalpha))-, 1392-24-1, ZINC4096134, Tox21_111513, BDBM50418089, CCG-38796, MFCD00075922, AKOS015965307, Tox21_111513_1, AC-8045, CS-1237, HBL0000164, SDCCGMLS-0066837.P001, NCGC00178483-01, NCGC00178483-02, NCGC00178483-04, NCGC00178483-05, NCGC00263659-01, AS-15249, CC-29957, HY-17411, O622, SC-13316, AB0016554, L0258, Limonin, from citrus seeds, >90% (HPLC), N1349, S2319, C03514, W-5068, 180L718, C-22706, Q-100083, BRD-K05906022-001-03-6, BRD-K05906022-001-05-1, (4aS,6aR,8aR,8bR,9aS,12S,12aS,14aR,14bR)-12-(Furan-3-yl)-6,6,8a,12a-tetramethyldecahydrooxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(1H,6H,8aH)-trione


ID: 1142

chemical graph of compound 1142



InChIKey: KBOPZPXVLCULAV-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1N)C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4075
synonyms found at PubChem are:
5-Aminosalicylic acid, Mesalazine, mesalamine, 5-Amino-2-hydroxybenzoic acid, 89-57-6, Pentasa, Claversal, Asacol, Canasa, Salofalk, Rowasa, 5-ASA, m-Aminosalicylic acid, Mesasal, Lialda, Fisalamine, Lixacol, Apriso, Benzoic acid, 5-amino-2-hydroxy-, p-Aminosalicylsaeure, Asacolitin, Mesalazina, Mesalazinum, sfRowasa, 5-amino-2-hydroxy-benzoic acid, Asacol HD, 5-Aminosalicylate, Mesalazinum [Latin], Pentacol, 5-Amino Salicylic Acid, 3-carboxy-4-hydroxyaniline, Mesalamine [USAN], Mesalazina [Spanish], p-Aminosalicylsaeure [German], 2-Hydroxy-5-aminobenzoic acid, Mesavancol, Mesacol, Mesavance, Mezavant, Iialda, Mesalazine MMX, SALICYLIC ACID, 5-AMINO-, Mezavant XL, UNII-4Q81I59GXC, NSC 38877, Mesalamine (USP), Pentasa (TN), Salofalk Granu-Stix, Apriso (TN), Asacol (TN), Canasa (TN), Lialda (TN), Rowasa (TN), 5-AS, CCRIS 7334, Mesalazine (JAN/INN), EINECS 201-919-1, BRN 2090421, AI3-15564, MLS001424012, 4Q81I59GXC, CHEBI:6775, 5-Aminosalicylic Acid, Purified, AJG-501, MAX-002, SPD-476, SPD-480, KBOPZPXVLCULAV-UHFFFAOYSA-N, mesalamine (USAN), Mesalamine HCl, MD-0901, CAS-89-57-6, NCGC00016344-03, SMR000145728, Z-206, DSSTox_CID_4506, DSSTox_RID_77435, DSSTox_GSID_24506, Asacolon, Ascolitin, Delzicol, Fivasa, 5 Aminosalicylate, 5-Aminosalicylicacid, m Aminosalicylic Acid, 5 Aminosalicylic Acid, Novo 5 ASA, Novo-5 ASA, meta Aminosalicylic Acid, meta-Aminosalicylic Acid, SR-01000763486, Hydrochloride, Mesalamine, Mesalamine [USAN:USP], Mesalamine Monosodium Salt, Monosodium Salt, Mesalamine, mesalsal, Salozinal, Asalit, Ipocol, HSDB 7512, minosalicylic acid, SPD 476, Mesalamine (TN), Delzicol (TN), Salofalk (TN), Sfrowasa (TN), Mesalazine [INN], Mesalazina[Spanish], Masacol (TN), Iialda (TN), Ipocal (TN), Mesalamine (Lialda), Novo5 ASA, 5-Aminosalicyclic acid, Meta-AminosalicylicAcid, 5-amino-salicylic acid, PubChem17623, Mesalamine|||Mesalazine, ACMC-1BKFR, Byk Brand of Mesalamine, AC1L1HCS, Falk Brand of Mesalamine, Prestwick0_001069, Prestwick1_001069, Prestwick2_001069, Prestwick3_001069, Axcan Brand of Mesalamine, WLN: ZR DQ CVQ, CHEMBL704, D0C4YC, Solvay Brand of Mesalamine, EC 201-919-1, Allphar Brand of Mesalamine, Antigen Brand of Mesalamine, cid_4075, Farmasa Brand of Mesalamine, Ferring Brand of Mesalamine, Merckle Brand of Mesalamine, Norgine Brand of Mesalamine, Celltech Brand of Mesalamine, Provalis Brand of Mesalamine, Oprea1_847633, SCHEMBL31297, 3amino-6-hydroxybenzoic acid, 5-amino-2-hydroxybenzoicacid, BSPBio_001058, KBioGR_002425, KBioSS_002431, 4-14-00-02058 (Beilstein Handbook Reference), KSC448C0L, MLS000758287, Novopharm Brand of Mesalamine, 5-Aminosalicylic acid, 95%, 5-Aminosalicylic acid, tablet, ARONIS23914, BIDD:GT0811, 3-amino-6-hydroxybenzoic acid, SmithKline Brand of Mesalamine, SPBio_002969, Yamanouchi Brand of Mesalamine, AC1Q51L9, BPBio1_001164, GTPL2700, ZINC1688, 5-Amino 2-hydroxy benzoic acid, DTXSID5024506, 5-Aminosalicylic acid, >=99%, 6291-36-7 (hydrochloride), BDBM60918, CTK3E8105, KBio2_002425, KBio2_004993, KBio2_007561, KBio3_002904, Salicylic acid, 5-amino-(8CI), cMAP_000045, MolPort-001-641-024, HMS1571E20, HMS2051M21, HMS2090I09, HMS2098E20, HMS3393M21, HMS3649K15, HMS3651M15, HMS3715E20, Pharmakon1600-01505993, Henning Berlin Brand of Mesalamine, BCP05326, GlaxoSmithKline Brand of Mesalamine, KS-00000CC5, KS-000048PQ, NSC38877, Schering Plough Brand of Mesalamine, Schering-Plough Brand of Mesalamine, Tox21_110384, Tox21_201610, Tox21_303125, 5-?Aminosalicylic Acid (Mesalazine), 5-Amino-2-hydroxybenzoic acid 97%, AN-874, ANW-39326, BBL013046, FC1035, MFCD00007877, NSC-38877, NSC759301, s1681, SBB052617, STK301678, Procter & Gamble Brand of Mesalamine, Sanofi Synthelabo Brand of Mesalamine, AKOS000118959, Tox21_110384_1, AC-2764, BCP9000175, CCG-100829, CS-2219, DB00244, HS-0100, LS-1894, LS11426, MCULE-5752745805, NC00079, NSC-759301, RP21708, RTR-032941, TRA0073805, NCGC00016344-01, NCGC00016344-02, NCGC00016344-04, NCGC00016344-05, NCGC00016344-07, NCGC00090934-01, NCGC00090934-02, NCGC00257142-01, NCGC00259159-01, 35589-28-7 (mono-hydrochloride salt), AJ-08068, BP-13074, BR-72925, CPD000145728, HY-15027, SAM001247020, SC-15695, 5-Aminosalicylic acid, analytical standard, AB1001921, KB-196569, KB-196728, ST2411704, ST4109571, TR-032941, A0317, AB00374979, AM20060091, FT-0619950, 1764-EP2272825A2, 1764-EP2275420A1, D00377, M-7246, 24215-EP2289518A1, 24215-EP2295053A1, 24215-EP2295409A1, 24215-EP2314574A1, 24215-EP2314590A1, 90701-EP2371811A2, AB00374979-09, AB00374979-10, AB00374979_11, AB00374979_12, 5-amino-2-hydroxybenzoic acid,5-Aminosalicylic acid, I06-0488, Q-201355, SR-01000763486-3, SR-01000763486-4, SR-01000763486-9, Z57127471, F1918-0003, 5-Amino-2-hydroxybenzoic acid; 5-AS; Mesalamine; 5-ASA, A3613/0153179, Mesalazine, European Pharmacopoeia (EP) Reference Standard, Mesalamine, United States Pharmacopeia (USP) Reference Standard, 5-aminosalicylic acid, Mesalazine, Asacol, Pentasa, Canasa, Mesalamine, Mesalamine, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11, Mesalazine for system suitability, European Pharmacopoeia (EP) Reference Standard, 61513-32-4, SCHEMBL18038934


ID: 1143

chemical graph of compound 1143



InChIKey: KBUKUKLNLPJWCO-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCOC2=CC=CC=C2)S(=O)(=O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"D Zhang" "Y Luo" "C Pavel" "GW Carlile" "DY Thomas" "SM Anjos" "JW Hanrahan" "N Liu" "R Robert" "J Liao"


CID is 2747481
synonyms found at PubChem are:
1-(benzenesulfonyl)-4-(2-phenoxyethyl)piperazine, MixCom1_000005, AC1MCMVR, AC1Q6VJV, Maybridge1_000005, Oprea1_668388, MolPort-001-841-346, ZINC19924752, AKOS008690847, MCULE-4730077666, Z46248350, 876686-44-1


ID: 1144

chemical graph of compound 1144



InChIKey: KBXIJIPYZKPDRU-UHFFFAOYSA-N
SMILES: C(C(=O)O)ON.C(C(=O)O)ON.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2723609
synonyms found at PubChem are:
2921-14-4, Carboxymethoxylamine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, Aminooxyacetic acid hemihydrochloride, 2-(Aminooxy)acetic acid hydrochloride (2:1), UNII-5G5QI2GN7A, 2-(Aminooxy)acetic acid hydrochloride(2:1), Acetic acid, (aminooxy)-, hydrochloride (2:1), Acetic acid, 2-(aminooxy)-, hydrochloride (2:1), 5G5QI2GN7A, Carboxymethoxyamine hemihydrochloride, (Aminooxy)acetic acid hemihydrochloride, Aminooxyacetic acid hemichloride, bis(2-(aminooxy)acetic acid) hydrochloride, EINECS 220-862-3, NSC 40358, NSC 50782, NSC 56446, AI3-52279, Acetic acid, (aminooxy)-, hemihydrochloride, O-Carboxymethylhydroxylamine hemihydrochloride, ACETIC ACID, 2-AMINOOXY-, HYDROCHLORIDE (2:1), Bis((aminooxy)acetic) acid hydrochloride, EU-0100007, Carboxymethoxylamine hemiHCl, AC1MC37X, SCHEMBL1091588, CHEMBL1492415, CTK8B7764, KBXIJIPYZKPDRU-UHFFFAOYSA-N, MolPort-006-114-801, 2-aminooxyacetic Acid Hydrochloride, KS-00000Y2F, Tox21_500007, ANW-58462, bis(aminooxyacetic acid) hydrochloride, carboxymethoxyl amine hemihydrochloride, (Carboxymethoxy)amine hemihydrochloride, AKOS016002992, 2-Aminooxyacetic acid hemihydrochloride, CC-1596, CCG-221311, CS-8158, LP00007, RTR-012749, NCGC00093533-01, NCGC00260692-01, 2-(Aminooxy)acetic acid hemihydrochloride, 2-(Aminooxy)acetic acid hydrochloride (2, HY-107994, FT-0623483, Hydroxylamine-O-acetic acid hemihydrochloride, ST24027601, O-carboxymethyl hydroxylamine hemihydrochloride, A 4508, O-(carboxymethyl) hydroxylamine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, 98%, Aminooxyacetic acid; (Carboxymethoxy)amine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, purum, >=97.0% (AT)


ID: 1145

chemical graph of compound 1145



InChIKey: KCBZSNWCUJBMHF-UHFFFAOYSA-F
SMILES: C1=CC(=C(C=C1S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C2=CC(=CC(=C2)NC(=O)NC3=CC(=CC(=C3)C(=O)NC4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC5=C(C=C(C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC6=C(C=C(C=C6)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4469
synonyms found at PubChem are:
NCGC00025139-01, Tocris-1391, GTPL4267, MolPort-003-983-648, HMS3267D22, 1,3-disodium 4-{[3-({[3,5-bis({2,4-bis[(sodiooxy)sulfonyl]phenyl}carbamoyl)phenyl]carbamoyl}amino)-5-({2,4-bis[(sodiooxy)sulfonyl]phenyl}carbamoyl)benzene]amido}benzene-1,3-disulfonate, NF449 octasodium salt, NF 449, octasodium 4-[[3-[[3,5-bis[(2,4-disulfonatophenyl)carbamoyl]phenyl]carbamoylamino]-5-[(2,4-disulfonatophenyl)carbamoyl]benzoyl]amino]benzene-1,3-disulfonate, 389142-38-5, 4,4',4'',4'''-[Carbonylbis-(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium, 627034-85-9, Lopac-N-4784, D0D9AA, AC1L1I8J, AC1O1BH3, CHEMBL1253351, AKOS024456567, CCG-208812, NCGC00016178-01, NCGC00016178-02, NCGC00094191-01, EU-0100867, N 4784, 4,4',4",4"'-[Carbonyl-bis[imino-5,1,3-benzenetriyl bis-(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid), 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt, NF-499, B6716


ID: 1146

chemical graph of compound 1146



InChIKey: KCECBJRHWSOTMR-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C(CO)O)O.COC1=C(C=CC(=C1)C(CO)O)O.C1CNCCN1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2723890
synonyms found at PubChem are:
MHPG piperazine, 67423-45-4, 4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt, MOPEG piperazine, 3-Methoxy-4-hydroxy-phenylglycol piperazine, DL-4-Hydroxy-3-methoxyphenylglycol piperazine salt, MHPG piperazine;, MOPEG piperazine;, EINECS 266-689-7, MOPEG piperidinium salt, AC1MC3TL, CHEMBL1593209, CTK8F6025, HMS3261B08, DL-4-Hydroxy-3-methoxyphenylethyleneglycol - piperazine (2:1), Tox21_500563, MFCD00065957, CCG-204653, LP00563, NCGC00093948-01, NCGC00261248-01, 4-Hydroxy-3-methoxyphenylglycol piperazine;, EU-0100563, FT-0641125, KS-00001835, 4-Hydroxy-3-methoxyphenylglycol hemipiperazine salt, 1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol; piperazine, 4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt, >=98.0% (HPLC), 1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol compound with piperazine (2:1)


ID: 1147

chemical graph of compound 1147



InChIKey: KCISFICQVCMQEX-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=COC3=C(C2=O)C(=CC(=C3OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3279840
synonyms found at PubChem are:
ISOTECTORIGENIN TRIMETHYL ETHER, 8-Hydroxygenistein-5,7,8,4'-tetramethyl ether, 5,7,8-trimethoxy-3-(4-methoxyphenyl)chromen-4-one, 13539-23-6, SPBio_000396, Spectrum_000765, SpecPlus_000147, AC1MM3MW, Spectrum2_000578, Spectrum3_000699, Spectrum4_001618, Spectrum5_000375, BSPBio_002457, KBioGR_001995, KBioSS_001245, SPECTRUM201341, DivK1c_006243, CHEMBL1481076, KBio1_001187, KBio2_001245, KBio2_003813, KBio2_006381, KBio3_001677, CHEBI:108594, CCG-38503, SDCCGMLS-0066384.P001, NCGC00095505-01, NCGC00095505-02, NCGC00178643-01, BRD-K10505056-001-02-0, 5,7,8-trimethoxy-3-(4-methoxyphenyl)-4H-chromen-4-one


ID: 1148

chemical graph of compound 1148



InChIKey: KCOOTJRKKIDHTM-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1C(=O)O)O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6710680
synonyms found at PubChem are:
HAEMATOMMIC ACID, 3-formyl-2,4-dihydroxy-6-methylbenzoic acid, Hamatommsaure, KBio2_006900, Spectrum_001284, 3-Formylorsellinic acid, Spectrum2_001922, Spectrum3_001118, Spectrum4_001959, Spectrum5_000699, AC1O8JW9, BSPBio_002856, KBioGR_002401, KBioSS_001764, SPECTRUM1400131, SPBio_001923, CHEMBL1315277, SCHEMBL13495709, KBio2_001764, KBio2_004332, KBio3_002076, CCG-38489, AKOS022645221, SDCCGMLS-0066839.P001, NCGC00095742-01, NCGC00095742-02, acide formyl-3-dihydroxy-2,4-methyl-6-benzoique, SR-05000002430, SR-05000002430-1, BRD-K03463894-001-02-7, 2-Hydroxy-3-(hydroxymethylene)-6-methyl-4-oxo-3,4-dihydrobenzoic acid, 479-25-4


ID: 1149

chemical graph of compound 1149



InChIKey: KCURWTAZOZXKSJ-JBMRGDGGSA-N
SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6252
synonyms found at PubChem are:
CYTARABINE HYDROCHLORIDE, Cytosine arabinoside hydrochloride, 69-74-9, Cytarabine HCl, Ara-C hydrochloride, 1-beta-D-Arabinofuranosylcytosine hydrochloride, Cytosar hydrochloride, Spongocytidine hydrochloride, Arabitin hydrochloride, Aracytin hydrochloride, Cylocide, Cytarabin hydrochloride, Arabinosylcytosine hydrochloride, Aracytidine hydrochloride, Cytarabine (hydrochloride), CCRIS 4774, Arabinosyl cytosine hydrochloride, Cytarabine hydrochloride [USAN], U-19920A, UNII-33K3DB6591, EINECS 200-713-9, Cytosine-1-beta-D-arabinofuranoside hydrochloride, C9H13N3O5.HCl, AI3-52344, MLS000028466, 1beta-D-Arabinofuranosylcytosine hydrochloride, 1beta-D-Arabinofuranosylcytosine monohydrochloride, 1-beta-D-Arabinofuranosylcytosine monohydrochloride, Cytosine, 1-beta-D-arabinofuranosyl-, hydrochloride, Cytosine, 1-beta-D-arabinofuranosyl-, monhydrochloride, Cytosine, 1beta-D-arabinofuranosyl-, monohydrochloride, 33K3DB6591, Cytosine beta-D-arabinofuranoside hydrochloride, SMR000058432, Arabinofuranosylcytosine hydrochloride, 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-, monohydrochloride, AC 1075, U 19920A, Cytarabine hydrochloride (USAN), Cytosine, 1-beta-D-arabinofuranosyl-, monohydrochloride, NSC 63878, 4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride, Alexan hydrochloride, SR-01000075773, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one hydrochloride, Cytosine Arabinoside HCl, Opera_ID_1542, DSSTox_CID_4891, AC1L1M4C, AC1Q3EJ1, Arabinocytidine hydrochloride, DSSTox_RID_77571, DSSTox_GSID_24891, SCHEMBL67288, MLS001148147, MLS002207299, 147-94-4 (Parent), CHEMBL1256472, DTXSID5024891, KCURWTAZOZXKSJ-JBMRGDGGSA-N, Tox21_300488, Tox21_500316, HY-13605A, MFCD00012839, 1-Beta-D-Arabinofuranosylcytosine HCl, AKOS015896936, AKOS015960559, AKOS015995277, CCG-221620, CS-2178, LP00316, LS-1589, RP29823, CAS-69-74-9, NCGC00093762-01, NCGC00254321-01, NCGC00261001-01, 29363-79-9, AC-11705, AN-41923, K172, KB-11375, 69-74-9 (HCL), 1-b-D-Arabinofuranosylcytosine hydrochloride, DB-025611, Cytosine-ss-D-arabinofuranoside hydrochloride, EU-0100316, FT-0083569, ST24046404, 1-beta-D-Arabinofuranosylcytosinehydrochloride, 1-(b-D-Arabinofuranosyl)cytosine hydrochloride, A-8763, C 6645, D03637, 069C749, C-49658, 1-(beta-d-arabino-furanosyl)-cytosine hydrochloride, SR-01000075773-1, Cytosine beta-D-arabinofuranoside hydrochloride, crystalline, CYTARABINE HYDROCHLORIDE (SEEALSO CYTARABINE 147-94-4), 2(1H)-Pyrimidinone,4-amino-1-b-D-arabinofuranosyl-,hydrochloride (1:1), Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Ara-C hydrochloride, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one hydrochloride, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one hydrochloride


ID: 1150

chemical graph of compound 1150



InChIKey: KCXVZYZYPLLWCC-UHFFFAOYSA-N
SMILES: C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

biological descriptors:

CFTR relevance: Fe3+ chelator, CFTR activator

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment unknown

reference list:

"G Wang"


CID is 6049
synonyms found at PubChem are:
EDTA, Edetic acid, Ethylenediaminetetraacetic acid, 60-00-4, Edathamil, Versene, Endrate, Havidote, Titriplex, EDTA acid, Sequestrol, Cheelox, Sequestric acid, Warkeelate acid, Gluma cleanser, Sequestrene aa, Komplexon ii, Quastal Special, Tetrine acid, Versene acid, Metaquest A, Trilon bw, Complexon II, Hamp-ene acid, Titriplex II, Cheelox BF acid, Trilon BS, Celon A, Chelest 3A, Questex 4H, Celon ATH, Chemcolox 340, Versenate, Acide edetique, Acido edetico, Acidum edeticum, Universne acid, Calcium disodium versenate, Vinkeil 100, Dissolvine E, Nullapon B acid, Nullapon bf acid, Perma kleer 50 acid, Nervanaid B acid, Clewat TAA, (Ethylenedinitrilo)tetraacetic acid, EDTA (chelating agent), Ethylenedinitrilotetraacetic acid, Caswell No. 438, Disodium EDTA, Chelaton 3, ICRF 185, Acide ethylenediaminetetracetique, Cheladrate, SEQ 100, Edetate calcium, Ethylenebisiminodiacetic acid, YD 30, Acide edetique [INN-French], Acido edetico [INN-Spanish], Acidum edeticum [INN-Latin], CCRIS 946, Edetate, ETHYLENEDIAMINE TETRAACETIC ACID, HSDB 809, Ethylenediamine-N,N,N',N'-tetraacetic acid, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, UNII-9G34HU7RV0, CaEDTA, Acetic acid, (ethylenedinitrilo)tetra-, Calcium disodium edetate, EPA Pesticide Chemical Code 039101, Edta disodium, Disodium edetate, Disodium versene, Endrate disodium, Kyselina ethylendiamintetraoctova, Sodium versenate, Edetic acid disodium salt, Ethylenediaminetetraacetate, Kyselina ethylendiamintetraoctova [Czech], Acide ethylenediaminetetracetique [French], Metaquest B, Kiresuto B, Chelaplex III, Complexon III, Diso-Tate, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, AI3-17181, Chelaton III, Potassium EDTA, Versene NA, Triplex III, Disodium versenate, Edathamil disodium, Trilon BD, Versene Na2, C10H16N2O8, Disodium sequestrene, Disodium tetracemate, EDTA disodium salt, EINECS 200-449-4, F 1 (complexon), EDTA, ion(4-), CHEMBL858, Sequestrene sodium 2, Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid, BRN 1716295, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, Edetate calcium disodium, 9G34HU7RV0, Perma Kleer Di Crystals, Calcium Disodium Edetate (JAN), Calcium disodium versenate (TN), CHEBI:42191, KCXVZYZYPLLWCC-UHFFFAOYSA-N, 4-04-00-02449 (Beilstein Handbook Reference), Ethylenediaminetetraacetic acid disodium salt, Edetate calcium disodium (USP), Sequestrene Na2, Trilon B, Selekton B2, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid, Disodium ethylenediaminetetraacetate, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, (ethylenedinitrilo)tetraacetic acid, ion(4-), Perma kleer 50 crystals disodium salt, Disodium (ethylenedinitrilo)tetraacetate, Disodium ethylenediaminetetraacetic acid, SODIUM ETHYLENEDIAMINETETRAACETATE, CBC 50152966, DR-16133, Ethylenediaminetetraacetate, disodium salt, Disodium diacid ethylenediaminetetraacetate, J-610078, D'E.d.t.a. disodique, Disodium (ethylenedinitrilo)tetraacetic acid, EDTA, 500 mM Solution, pH 8.0, ULTROL&reg; Grade, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, Disodium dihydrogen ethylenediaminetetraacetate, Tetracemate, Edetates, Disodium dihydrogen(ethylenedinitrilo)tetraacetate, 139-33-3, Calcium Tetacine, Distannous EDTA, Chromium EDTA, Stannous EDTA, Gallium EDTA, Copper EDTA, NSC2760, 470462-56-7, Disodium Calcitetracemate, N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], NCGC00159485-02, ETHYLENEDIAMINETETRAACETIC ACID, ACS, Edetic acid [INN:BAN], Ethylene Dinitrilotetraacetate, disodium-edta, Edetic acid [INN:BAN:NF], Ethylenebis(iminodiacetic acid), (Ethylenedinitrilo)tetraacetic acid, disodium salt, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid, Techrun DO, H4edta, Zonon AO, EDTA, free acid, EDTA, free base, Versene acid (TN), Disodium Ethylene Dinitrilotetraacetate, Edetic Acid, Disodium, Magnesium Salt, Acroma DH 700, Spectrum_001018, ACMC-209mhe, AC1L1LOX, Edetic acid (NF/INN), 10058-42-1, Spectrum2_000003, Spectrum3_000412, Spectrum4_000531, Spectrum5_000955, Edetic acid [BAN:INN], DSSTox_CID_2977, D00KEP, D01DTJ, EC 200-449-4, DSSTox_RID_76814, DSSTox_GSID_22977, ethylenediaminetetracetic acid, BSPBio_001964, Diaminoethane-tetraacetic acid, Diaminoethanetetra-acetic acid, Ethylenediamineteraacetic Acid, KBioGR_001161, KBioSS_001498, KSC352S1H, MLS001249457, BIDD:ER0565, DivK1c_000777, ethylenediamine tetracetic acid, SPBio_000005, ethylenediamine-tetraacetic acid, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-, DTXSID6022977, ethylene diamine tetraacetic acid, ethylene-diamine tetraacetic acid, (ethylenedinitrilo)tetraaceticacid, CTK2F2913, KBio1_000777, KBio2_001498, KBio2_004066, KBio2_006634, KBio3_001184, BIE0729, EBD3431, Ethylenedinitrilo-tetraacetic acid, (Ethylenedintrilo)tetraacetic acid, MolPort-001-788-408, NINDS_000777, ZX-AFC000762, 7379-27-3 (potassium salt), 24669-13-4 (chromium salt), KS-00000G4L, 7379-28-4 (hydrochloride salt), Tox21_202736, 2001-94-7 (di-potassium salt), ANW-33408, BDBM50330325, GE4011, MFCD00003541, SBB008807, STK386291, ZINC19364242, 139-33-3 (di-hydrochloride salt), AKOS001574475, Glycine, (N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, labeled with carbon-14, (ethane-1,2-diyldinitrilo)tetraacetate, CHM0029903, DB00974, MCULE-1868494404, RL04264, RTR-020771, ZC00001, 53404-51-6 (mono-potassium salt), CAS-60-00-4, IDI1_000777, NCGC00159485-03, NCGC00159485-04, NCGC00260284-01, 10058-42-1 (iron(3+) salt), 17421-79-3 (mono-hydrochloride salt), 688-55-1, AC-10615, ACM470462567, AJ-72922, AN-19025, AN-23308, AN-41801, LS-12098, SC-18421, SMR000058776, ST072179, SBI-0051360.P003, (ethane-1,2-diyldinitrilo)tetraacetic acid, KB-296903, TR-020771, 76353-66-7 (calcium,hydrochloride salt), B7197, E0084, Ethylenediaminetetraacetic acid, 2Na (EDTA), Ethylenediaminetetraacetic acid, 99% 500g, Ethylenediaminetetraacetic acid, LR, >=98%, FT-0083197, FT-0626319, ST24030413, C00284, D00052, Ethylenediaminetetraacetic acid, p.a., 98.0%, AB00053468_03, Ethylenediaminetetraacetic acid solution, 0.02 N, Ethylenediaminetetraacetic acid, >=98.0% (KT), 6381-92-6 (di-hydrochloride salt, di-hydrate), A832566, N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, SR-01000883946, I04-0860, SR-01000883946-1, 37C3C5E7-D921-445F-82D6-FEBF1AE5AEF5, I14-19418, Z2688689169, Ethylenediaminetetraacetic acid, BioUltra, >=99.0% (KT), Ethylenediaminetetraacetic acid, 99.995% trace metals basis, Ethylenediaminetetraacetic acid, SAJ special grade, >=99.0%, Ethylenediaminetetraacetic acid, Vetec(TM) reagent grade, 98%, [{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]acetic acid, 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Edetic acid, United States Pharmacopeia (USP) Reference Standard, Edetic acid; EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil, Ethylenediaminetetraacetic acid, ACS reagent, 99.4-100.6%, powder, Ethylenediaminetetraacetic acid, purified grade, >=98.5%, powder, 2,2'',2'''',2''''''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Ethylenediaminetetraacetic acid, BioUltra, anhydrous, >=99% (titration), Glycine, N,N'-1, {2-ethanediylbis[N-(carboxymethyl)-,} disodium salt, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid(EDTA), 2-[2-[bis(2-hydroxy-2-oxoethyl)amino]ethyl-(2-hydroxy-2-oxoethyl)amino]ethanoic acid, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, Redi-Dri(TM), >=98%, 13440-78-3, 161122-33-4, 20539-27-9, 26627-46-3, 30485-87-1, 30485-88-2, 30485-90-6, 32757-10-1, 402925-67-1, 675141-16-9, 94108-75-5, Ethylenediamine-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetraacetic Acid-13C4 (|A-labels), Ethylenediaminetetraacetic acid solution, 0.02% in DPBS (0.5 mM), sterile-filtered, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid solution, BioUltra, for molecular biology, pH 8.0, ~0.5 M in H2O, Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, powder, Redi-Dri(TM), ACS reagent, 99.4-100.6%, InChI=1/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20, AC1NR0SS, 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)azaniumyl]ethyl]azaniumyl]acetate


ID: 1151

chemical graph of compound 1151



InChIKey: KDFBGNBTTMPNIG-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)CCN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 67652
synonyms found at PubChem are:
Tryptamine hydrochloride, 343-94-2, 3-(2-Aminoethyl)indole hydrochloride, 2-(1H-indol-3-yl)ethanamine hydrochloride, 1H-Indole-3-ethanamine, monohydrochloride, Tryptamine monohydrochloride, TRYPTAMINEHYDROCHLORIDE, CCRIS 4419, UNII-2942LD1Q06, Indole-3-ethylamine hydrochloride, 3-(2-Aminoethyl)-1H-indole monohydrochloride, beta-Indole-ethylamine hydrochloride, EINECS 206-446-4, beta-3-Indolylethylamine hydrochloride, NSC 522258, 2-(Indol-3-yl)ethylamine hydrochloride, beta-Indolaethylamin-chlorhydrat [German], AI3-24258, 1H-Indole-3-ethanamine, hydrochloride (1:1), 2-(3-Indolyl)ethylamine hydrochloride, 2942LD1Q06, Indole, 3-(2-aminoethyl)-, monohydrochloride, T-8150, 2-indol-3-ylethylamine, chloride, 61-54-1 (Parent), tryptamine-hcl, beta-Indolaethylamin-chlorhydrat, SR-01000075589, Tryptamine HCl, Tryptamine, HCl, PubChem9449, 2-(1h-indol-3-yl)ethanaminhydrochlorid, Tryptamine hydrochloride salt, SCHEMBL274183, ACMC-209i75, Tryptamine hydrochloride, 99%, AC1L280T, AC1Q38V6, Jsp006237, CHEMBL1255796, DTXSID9059836, CTK3J1227, KS-00000WGJ, KDFBGNBTTMPNIG-UHFFFAOYSA-N, MolPort-003-928-498, .beta.-Indolaethylamin-chlorhydrat, Tox21_500061, WLN: T56 BMJ D2Z & GH, ANW-27855, MFCD00012682, NSC522258, RW3341, SBB000359, AKOS004910399, API0004536, CCG-221365, LP00061, NSC-522258, QC-2231, RTR-030642, .beta.-Indole-ethylamine, hydrochloride, 3-(beta-aminoethyl)-indole hydrochloride, NCGC00093575-01, NCGC00260746-01, .beta.-3-Indolylethylamine, hydrochloride, AC-25536, AN-23410, AS-11527, LS-82296, LS-82297, 2-(1H-Indol-3-yl)ethanaminehydrochloride, 2-(1H-indol-3-yl)ethanamine,hydrochloride, AB0010248, AX8156046, DB-048617, KB-177063, TR-030642, 2-(1H-Indol-3-yl);ethanamine hydrochloride, A0300, EU-0100061, FT-0631988, ST24027440, ST50308497, 2-(1H-indol-3-yl)-ethylamine hydrochloride salt, C-49605, I10-0178, SR-01000075589-1, MolPort-000-736-788, MCULE-2705006421


ID: 1152

chemical graph of compound 1152



InChIKey: KDUWXMIHHIVXER-UHFFFAOYSA-N
SMILES: CCC(=O)C1=CC=CC=C1O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"LJ Galietta" "MH Nantz" "AS Verkman" "K By" "EJ Niedzinski" "MF Springsteel" "MJ Kurth" "M Eda" "MJ Haddadin"


CID is 69133
synonyms found at PubChem are:
2'-Hydroxypropiophenone, 610-99-1, 1-(2-hydroxyphenyl)propan-1-one, 2-Propionylphenol, 1-Propanone, 1-(2-hydroxyphenyl)-, o-Hydroxypropiophenone, o-Propiophenol, Propiophenone, 2'-hydroxy-, UNII-ZGH9CA1BFI, ZGH9CA1BFI, ortho-Hydroxypropiophenone, KDUWXMIHHIVXER-UHFFFAOYSA-N, 1-Propanone,1-(2-hydroxyphenyl)-, 2 -Hydroxypropiophenone, NSC3785, EINECS 210-244-1, 2-(Propionyl)phenol, PubChem21422, ACMC-1AYBX, AI3-11684, 2'-hydroxy-propiophenone, 2/'-Hydroxypropiophenone, 2\'-Hydroxypropiophenone, Propiophenone, o-hydroxy-, EC 210-244-1, AC1L2B6V, AC1Q5FM4, 2-Hydroxyphenyl ethyl ketone, Ethyl 2-Hydroxyphenyl Ketone, SCHEMBL111675, 2'-Hydroxypropiophenone, 97%, CHEMBL151116, CTK5B2704, DTXSID90209868, MolPort-001-783-849, 1-(2-Hydroxyphenyl)-1-propanone, ZINC391093, KS-00000UX5, NSC-3785, ANW-33683, BBL011846, MFCD00002220, SBB063301, STL163409, 1-(2-Hydroxyphenyl)-1-propanone #, AKOS000121339, MCULE-6236011886, RP21360, AC-10642, AN-46456, AS-12054, SC-76192, TC-122428, FT-0612634, ST50824215, 2 inverted exclamation marka-Hydroxypropiophenone, I01-1175, W-105197, F1908-0078, 1-(2-HYDROXYPHENYL)-PROPANONE (2-HYDROXY-PROPIOPHENONE), InChI=1/C9H10O2/c1-2-8(10)7-5-3-4-6-9(7)11/h3-6,11H,2H2,1H


ID: 1153

chemical graph of compound 1153



InChIKey: KFEAUMZKRNJEDU-BTJKTKAUSA-N
SMILES: CC1=C(C2=C(N1)C=CC(=C2)O)CCN.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 9836150
synonyms found at PubChem are:
2-Methylserotonin maleate, 2-Methylserotonin maleate salt, 78263-91-9, EU-0100813, SCHEMBL1320833, CHEMBL1491258, AOB5681, MolPort-035-944-445, HMS3262D07, Tox21_500813, AKOS025142140, CCG-222117, LP00813, NCGC00094146-01, NCGC00261498-01, LS-194105, 2-Methylserotonin maleate, >=95% (HPLC), M-109, SR-01000075557-1


ID: 1154

chemical graph of compound 1154



InChIKey: KFJZVXKPPQIYCG-UHFFFAOYSA-N
SMILES: CCN(CC)CCCCCCCCOC(=O)C1=CC(=C(C(=C1)OC)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 150613
synonyms found at PubChem are:
CCRIS 7561, EINECS 258-574-5, 3,4,5-Trimethoxybenzoic acid, 8-(diethylamino)octyl ester, hydrochloride, Diethyl(8-(3,4,5-trimethoxybenzoyloxy)octyl)ammonium chloride, 3,4,5,-Trimethoxybenzoic acid 8-(diethylamino)octyl ester hydrochloride, AC1L44OR, 57818-92-5 (Parent), LS-182391, diethyl-[8-(3,4,5-trimethoxybenzoyl)oxyoctyl]azanium chloride, 53464-72-5, TMB-8 hydrochloride, 8-(Diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride, TMB-8, Hydrochloride, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate, IN1056, 8-(N,N-Diethylamino)-octyl-3,4,5-trimethoxybenzoate, HCl, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride, 3,4,5-Trimethoxybenzoic Acid 8-(Diethylamino)octyl Ester, Hydrochloride, 3,4,5-Trimethoxybenzoic Acid 8-Diethylamino-n-octyl Ester Hydrochloride, TMB 8 hydrochloride, AC1OCEPW, MLS002153307, ACMC-1B069, SCHEMBL5682553, CHEMBL1256666, CTK8C5800, REGID_for_CID_6917843, Tox21_500022, NSC379318, AKOS015888376, CCG-221326, LP00022, MCULE-2208552656, NSC-379318, NCGC00093545-01, NCGC00260707-01, SMR001230723, TC-168061, EU-0100022, FT-0614162, TMB-8 inverted exclamation mark currency HCl, C-49531, SR-01000075348, SR-01000075348-1, I01-10369, 3,4,5-TRIMETHOXYBENZOIC ACID 8-(DIETHYLAMINO) OCTYL ESTER, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride, 97%, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride


ID: 1155

chemical graph of compound 1155



InChIKey: KFVSLSTULZVNPG-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 31620
synonyms found at PubChem are:
Terbutaline sulphate, Bricanyl Turbuhaler, Terbutaline sulfate, EINECS 245-386-3, 1-(3,5-Dihydroxyphenyl)-2-tert-butylaminoethanol sulphate, (+-)-alpha-((tert-Butylamino)methyl)-3,5-dihydroxybenzyl alcohol sulfate (2:1) (salt), 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, sulfate (2:1) (salt), BENZYL ALCOHOL, alpha-((tert-BUTYLAMINO)METHYL)-3,5-DIHYDROXY-, SULFATE (2:1), AC1L1LZE, AC1Q22KP, Terbutaline sulfate [USAN:JAN], KFVSLSTULZVNPG-UHFFFAOYSA-N, 23031-25-6 (Parent), Terbutaline sulfate [USAN:USP:JAN], LS-42744, tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium sulfate, 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol sulfate(2:1), 98225-49-1, 23031-32-5, TERBUTALINE HEMISULFATE, Terbutaline hemisulfate salt, 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, Brethine (TN), DSSTox_CID_25437, DSSTox_RID_80878, DSSTox_GSID_45437, 2-t-Butylamino-1-[3,5-dihydroxyphenyl]ethanol, 5-(2-(tert-butylamino)-1-hydroxyethyl)benzene-1,3-diol hemisulfate, Terbutalin sulfate, 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol;sulfuric acid, Prestwick_598, Terbutaline(sulfate), Terbutaline (sulfate), 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol; sulfuric acid, bis(5-(2-(tert-butylamino)-1-hydroxyethyl)benzene-1,3-diol) sulfate, Terbutaline sulfuric acid, AC1L9AZM, NCGC00016772-01, CAS-23031-32-5, SCHEMBL26462, CHEBI:9450, sulfuric acid; bis(terbutaline), CHEMBL1315867, DTXSID3045437, CTK8G3346, C24H40N2O10S, MolPort-003-959-699, Terbutaline sulfate (JP17/USP), HMS1569O03, HMS2096O03, HMS3263B13, HMS3713O03, BCP09034, KS-00001F8N, Tox21_110602, Tox21_501126, MFCD00079584, AKOS015909692, Tox21_110602_1, API0005421, CCG-220391, CCG-222430, LP01126, NCGC00016010-09, NCGC00094394-01, NCGC00261811-01, EU-0101126, FT-0674863, V0238, D00688, T 2528, 031T325, SR-01000872654, SR-01000872654-1, I14-31834, F2173-0944, Terbutaline sulfate, British Pharmacopoeia (BP) Reference Standard, Terbutaline sulfate, European Pharmacopoeia (EP) Reference Standard, Terbutaline sulfate, United States Pharmacopeia (USP) Reference Standard


ID: 1156

chemical graph of compound 1156



InChIKey: KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 11065
synonyms found at PubChem are:
Amitriptyline hydrochloride, 549-18-8, Amitriptyline HCl, Annoyltin, Tryptizol, Domical, Elavil hydrochloride, Lentizol, Saroten, Amavil, Ami-Anelun, Amineurin, Anapsique, Daprimen, Elatrolet, Maxivalet, Miketorin, Mitaptyline, Rantoron, Sarotena, Syneudon, Trepiline, Triptizol, Tryptine, Trytomer, Vanatrip, Yamanouchi, Amilit, Amiplin, Amiprin, Amitid, Amitrip, Amyline, Amyzol, Belpax, Elatrol, Enafon, Etrafon, Etravil, Kyliran, Larozyl, Levate, Pinsanu, Pinsaun, Teperin, Triavil, Tridep, Tripta, Trynol, Damilen hydrochloride, Endep, Amitriptyline chloride, Saroten Retard, Tryptizol retard, Tryptacap hydrochloride, Apo-Amitriptyline, ADT-Zimaia, Oasil-M, Novoprotect, Novotriptyn, Nornaln, Proheptadien monohydrochloride, sk-Amitriptyline chloride, CCRIS 7092, UNII-26LUD4JO9K, Amitriptyline (hydrochloride), EINECS 208-964-6, Amitryptiline hydrochloride, NIH 10794, NSC 104210, 26LUD4JO9K, Annolytin, MLS000028437, component of Etrafon, component of Triavil, CPD000058368, SMR000058368, Amitryptyline hydrochloride, Elavil (TN), 5-(3-Dimethylaminopropylidene)dibenzo(a,d)(1,4)cycloheptadiene hydrochloride, C20H24ClN, DSSTox_CID_13187, DSSTox_RID_79055, DSSTox_GSID_33187, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine hydrochloride, W-105596, 50-48-6 (Parent), 1-propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, NSC169910, WLN: L C676 BY&T&J BU3N1&1 &GH, SR-01000003046, NCGC00015095-09, CAS-549-18-8, Amilent, Amicen, Euplit, Uxen, 5-(3-Dimethylaminopropylidene)dibenzo[a,4]cycloheptadiene hydrochloride, 5-[3-(Dimethylamino)propylidene]dibenzo[a,4]cycloheptadiene hydrochloride, 1-Propanamine,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene hydrochloride, 5H-Dibenzo[a,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo[a,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-,hydrochloride, Amitriptyline hydrochloride [JAN], Prestwick_20, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1), 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1), 3-(10,11-dihydro-5h-dibenzo[a,d]cycloheptene-5-ylidene)-n,n-dimethyl-1-propanamine hydrochloride, 3-(5,6-dihydrodibenzo[2,1-b:1',2'-e][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride, DRG-0169, Amitriptyline hydrochloride [USP:JAN], PubChem21398, Opera_ID_618, Nortriptyline Impurity F, AC1L1WJE, Amitryptylline hydrochloride, AC1Q38XC, SCHEMBL41079, MLS001055393, MLS001074176, MLS002222152, SPECTRUM1500117, REGID_for_CID_11065, CHEBI:2667, CHEMBL1200964, DTXSID9033187, HY-B0527A, Amitriptyline Hydrochloride ,(S), Amitriptyline hydrochloride, 99%, KFYRPLNVJVHZGT-UHFFFAOYSA-N, MolPort-003-666-120, ZX-AFC003121, HMS1568O09, HMS1920C13, Pharmakon1600-01500117, 549-18-8(hcl), KS-00000FN4, Tox21_113122, Tox21_201278, Tox21_303612, Tox21_500112, BG0033, BI3855, CCG-38919, MFCD00012537, NSC104210, NSC755869, s3183, AKOS015994716, Tox21_113122_1, API0001458, CS-2751, KS-1291, LP00112, NC00497, NSC-104210, NSC-169910, NSC-755869, Amitriptyline hydrochloride (JP17/USP), Amitriptyline;Amitriptyline hydrochloride, NCGC00015095-15, NCGC00024433-03, NCGC00024433-05, NCGC00093609-01, NCGC00093609-02, NCGC00093609-03, NCGC00093609-04, NCGC00093609-05, NCGC00257393-01, NCGC00258830-01, NCGC00260797-01, AK162589, AN-23652, H905, KB-47353, LS-60749, SAM002554886, AB0013348, AX8114039, A0908, EU-0100112, FT-0662108, ST24045948, A 8404, D00809, J10484, Amitriptyline hydrochloride, >=98% (TLC), powder, SR-01000003046-2, SR-01000003046-6, 5-(3-(Dimethylamino)propylidene) dibenzosuberane HCl, F0001-1443, Amitriptyline Hydrochloride 1.0 mg/ml in Methanol (as free base), Amitriptyline hydrochloride, drug standard, 1.0 mg/mL in methanol, Amitriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Amitriptyline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Amitriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine hydrochloride, 3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride, 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-,hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (8CI), 5H-Dibenzo[a,d]cycloheptene-Delta(sup5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (6CI,8CI), 8058-15-9, dimethyl({3-[(2Z)-tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine hydrochloride, dimethyl({3-[(2Z)-tricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]propyl})amine hydrochloride, AC1LCWFY, AKOS015917367, I14-9588, (3-(5,6-dihydrodibenzo[b,f][7]annulen-11-ylidene)propyl)dimethylamine, chlorid e, MolPort-000-696-255, SBB057420, AKOS024366256, MCULE-6119641097, ST50999679


ID: 1157

chemical graph of compound 1157



InChIKey: KGMMGVIYOHGOKQ-APTPAJQOSA-N
SMILES: CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 9931141
synonyms found at PubChem are:
(-)-trans-(1S,2S)-U-50488 hydrochloride, CHEMBL593781, 114528-79-9, SR-01000075483, SR-01000597740, 133162-85-3, trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride, MLS000862195, SCHEMBL7115846, AOB4833, MolPort-003-959-847, Tox21_501266, AKOS024458435, CCG-222570, LP01266, NCGC00094503-01, NCGC00261951-01, SMR000326958, NCG-C00094503-01, LS-191065, (-)-Trans-(1S,2S)-U-50488 HCl, EU-0101266, U-111, ()-trans-(1S,2S)-U-50488 hydrochloride, SR-01000075483-1, SR-01000075483-2, SR-01000597740-1, SR-01000597740-2, SR-01000597740-3, trans-(1S,2S)-3,4-Dichloro-N-methyl-N-(2-[1-pyrollidinyl]cyclohexyl)benzeneacetamide hydrochloride


ID: 1158

chemical graph of compound 1158



InChIKey: KGMMGVIYOHGOKQ-JAXOOIEVSA-N
SMILES: CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6918162
synonyms found at PubChem are:
(+)-U-50488 hydrochloride, U50488 Hydrochloride, (+/-)-U-50488 hydrochloride, (+)-trans-(1R,2R)-U-50488 hydrochloride, 114528-81-3, U-50488 hydrochloride, KGMMGVIYOHGOKQ-JAXOOIEVSA-N, AC1OCF3F, 107902-84-1, C19H26Cl2N2O.HCl, CHEMBL1256834, SCHEMBL10386320, SYN5230, MolPort-003-959-846, 67198-17-8, AKOS024458305, NCGC00094496-01, LS-28506, NCG-C00094496-01, LS-191064, (+)-Trans-(1R,2R0-U-50488 HCl, EU-0101256, U-110, 114528-81-3 (HCl), 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide hydrochloride, trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride, trans-(1R,2R)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide hydrochloride


ID: 1159

chemical graph of compound 1159



InChIKey: KGPAYJZAMGEDIQ-UHFFFAOYSA-N
SMILES: CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 15548
synonyms found at PubChem are:
Laudanosine, DL-Laudanosine, 1699-51-0, (+-)-Laudanosine, (R,S)-Laudanosine, Laudanosine (R,S), EINECS 216-923-9, NSC 94267, AI3-61890, 20412-65-1, NSC35045, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, 5',8-Dimethoxylaudanosine hydrochloride, (+-)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline, ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-VERATRYL-, (+-)-, (1)-1-((3,4-Dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline, 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoqu inoline, SMR000064381, Veraisoquin, dl-Laudanosin, Prestwick_292, Spectrum_000863, (.+-.)-Laudanosine, SpecPlus_000088, AC1Q4CGO, Prestwick0_000591, Prestwick1_000591, Prestwick2_000591, Prestwick3_000591, Spectrum2_000663, Spectrum3_000112, Spectrum4_000934, Spectrum5_001625, (.+/-.)-Laudanosine, DL-Laudanosine, free base, D01VUF, D0F7FX, CHEMBL1407, Oprea1_379167, BSPBio_000462, BSPBio_001724, KBioGR_001488, KBioSS_001343, MLS000060551, MLS002634637, DivK1c_006184, SCHEMBL466529, SPBio_000725, SPBio_002681, AC1L264I, BPBio1_000510, ISO024, CHEBI:91599, CTK8H5184, KBio1_001128, KBio2_001343, KBio2_003911, KBio2_006479, KBio3_000864, KGPAYJZAMGEDIQ-UHFFFAOYSA-N, MolPort-001-728-151, HMS1569H04, HMS2096H04, HMS2271K11, AZD-9684, NSC94267, 6638AH, CCG-38566, NSC-35045, NSC-94267, NSC331268, AKOS001094404, AKOS022144164, MCULE-1703608488, NE49236, NSC-331268, isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, NCGC00017301-02, NCGC00142367-01, AS-37336, LS-85945, ST023493, AB00052572, FT-0625478, AB00052572-12, BRD-A24817035-001-05-4, Isoquinoline,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+/-.)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline, Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+/-.)-, Isoquinoline,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+-.)-, Isoquinoline,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (+-)-, Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (+-)- (9CI), Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (.+/-.)-, Isoquinoline,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (.+-.)-


ID: 1160

chemical graph of compound 1160



InChIKey: KGQZGCIVHYLPBH-UHFFFAOYSA-N
SMILES: CC1=NC2=C(N1)C(=O)N(C(=O)N2CC3=CC=CO3)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 3433
synonyms found at PubChem are:
Furafylline, 80288-49-9, Furafylline [INN], Furafilina [Spanish], Furafyllinum [Latin], UNII-C2087G0XX3, 3-Furfuryl-1,8-dimethylxanthine, 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione, CHEMBL405845, C2087G0XX3, NCGC00015426-04, DSSTox_CID_25153, DSSTox_RID_80707, DSSTox_GSID_45153, 3-(furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione, Furafilina, Furafyllinum, 3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione, 1H-Purine-2,6-dione,3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-, CAS-80288-49-9, Lopac-F-124, AC1L1FXB, AC1Q6KZJ, Lopac0_000538, SCHEMBL191214, 1,8-dimethyl-3-(2'-furfuryl)-1H-purine-2,6-dione, DTXSID2045153, CTK5E7657, Furafylline, >=98% (HPLC), KGQZGCIVHYLPBH-UHFFFAOYSA-N, MolPort-003-941-353, HMS2089A08, HMS3261L17, BCP20952, ZINC9227032, Tox21 110143, Tox21_110143, Tox21_500538, 3-(2-furylmethyl)-1,8-dimethyl-3,7-dihydro-1h-purine-2,6-dione, BDBM50236897, IN2357, AKOS027380039, Tox21_110143_1, API0026273, CCG-204628, LP00538, NCGC00015426-01, NCGC00015426-02, NCGC00015426-03, NCGC00015426-05, NCGC00015426-06, NCGC00015426-07, NCGC00015426-08, NCGC00015426-09, NCGC00093927-01, NCGC00093927-02, NCGC00093927-03, NCGC00093927-04, NCGC00261223-01, HY-107204, LS-177546, CS-0027630, EU-0100538, F-124, BIM-0050521.0001, AB01275435-01, SR-01000076233, SR-01000076233-1, 3-(2-furfuryl)-1,8-dimethyl-7H-purine-2,6-quinone, 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione, 3-(furan-2-ylmethyl)-1,8-dimethyl-3,7-dihydro-1H-purine-2,6-dione


ID: 1161

chemical graph of compound 1161



InChIKey: KGSSUTVUTPLSQW-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(O1)C=C3C(=C2O)C(=O)C(=CO3)C4=CC5=C(C=C4)OCO5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5983661
synonyms found at PubChem are:
robustone, KBio1_001150, Spectrum_000344, SpecPlus_000110, Spectrum3_001734, Spectrum4_001545, Spectrum5_000110, BSPBio_003408, KBioGR_002010, KBioSS_000824, SPECTRUM210454, DivK1c_006206, AC1O09P3, CHEMBL252722, KBio2_000824, KBio2_003392, KBio2_005960, KBio3_002628, CCG-39587, LMPK12050245, SDCCGMLS-0066478.P001, NCGC00095520-01, NCGC00095520-02, NCGC00178085-01, BRD-K16117851-001-01-7, 7-(1,3-benzodioxol-5-yl)-5-hydroxy-2,2-dimethylpyrano[3,2-g]chromen-6-one, 22044-56-0


ID: 1162

chemical graph of compound 1162



InChIKey: KGXLWYQCBAUILI-NBHKXLOCSA-N
SMILES: CC(CCC(=O)O)[C@H]1CCC2[C@@]1(C=CC3C2CC[C@H]4[C@@]3(CCC(=O)C4)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708687
synonyms found at PubChem are:
chol-11-enic acid, KBio3_001749, Spectrum_001203, SpecPlus_000465, AC1O8FJJ, Spectrum2_000625, Spectrum3_000715, Spectrum4_001883, Spectrum5_000506, BSPBio_002529, KBioGR_002410, KBioSS_001683, DivK1c_006561, SPBio_000590, SCHEMBL18407107, KBio1_001505, KBio2_001683, KBio2_004251, KBio2_006819, CCG-39166, NCGC00178618-01, SR-05000002628, SR-05000002628-1, 4-[(5R,10S,13R,17R)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid


ID: 1163

chemical graph of compound 1163



InChIKey: KGYCKUADVHYVLM-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC3(C(O3)CCC2(C)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5024745
synonyms found at PubChem are:
2-HYDROXY-5 (6)EPOXY-TETRAHYDROCARYOPHYLLENE, KBio2_001190, Spectrum_000710, SpecPlus_000234, Spectrum2_001775, Spectrum3_001309, Spectrum4_001461, Spectrum5_000101, BSPBio_002977, KBioGR_002001, KBioSS_001190, SPECTRUM300119, DivK1c_006330, SPBio_001669, CHEMBL1562729, KBio1_001274, KBio2_003758, KBio2_006326, KBio3_002197, CCG-38424, SDCCGMLS-0066475.P001, NCGC00095589-01, NCGC00095589-02, SR-05000002483, SR-05000002483-1


ID: 1164

chemical graph of compound 1164



InChIKey: KHARQKXCINHICJ-WSPQHGNJSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@](CCCC2(C)C)(C3[C@@]1(C4=CC(=O)O[C@H]([C@@]4(CC3)C)C5=COC=C5)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 6708592
synonyms found at PubChem are:
KBio1_001217, Spectrum_000696, SpecPlus_000177, AC1O8FEO, Spectrum2_000261, Spectrum3_000053, Spectrum4_001335, Spectrum5_000209, BSPBio_001805, KBioGR_001829, KBioSS_001176, DEOXODEOXYDIHYDROGEDUNIN, DivK1c_006273, SPBio_000102, SCHEMBL12998461, KBio2_001176, KBio2_003744, KBio2_006312, KBio3_000985, CCG-39821, NCGC00178994-01, BRD-A98490861-001-02-7, [(1R,4bR,5R,10aS,12aR)-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-5-yl] acetate


ID: 1165

chemical graph of compound 1165



InChIKey: KHOITXIGCFIULA-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 2391
synonyms found at PubChem are:
bisacodyl, 603-50-9, Dulcolax, Bicol, Brocalax, Durolax, Dulcolan, Endokolat, Fenilaxan, Hillcolax, Sanvacual, Stadalax, Theralax, Eulaxan, Godalax, Ivilax, Laxadin, Laxans, Laxine, Laxorex, Neolax, Nigalax, Pyrilax, Telemin, Ulcolax, Zetrax, Sk-bisacodyl, Laxanin N, Bisacodylum, Bisacodilo, Deficol, LACO, LA96a, Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester), HalfLytely, Bisacodylum [INN-Latin], Bisacodilo [INN-Spanish], (Pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate, Bis(p-acetoxyphenyl)-2-pyridylmethane, Di-(p-acetoxyphenyl)-2-pyridylmethane, Di-(4-acetoxyphenyl)-2-pyridylmethane, MLS000069729, UNII-10X0709Y6I, 2-(4,4'-Diacetoxydiphenylmethyl)pyridine, C22H19NO4, HSDB 3016, (4,4'-Diacetoxydiphenyl)(2-pyridyl)methane, 4,4'-(2-Pyridylmethylene)diphenol diacetate, EINECS 210-044-4, BRN 0323727, 4,4'-(2-Pyridylmethylene)diphenol diacetate (ester), 4,4'-Diacetoxydiphenylpyridyl-2-methane, SMR000058226, MLS002701749, Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate (ester), Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-diacetate, KHOITXIGCFIULA-UHFFFAOYSA-N, NSC614826, 10X0709Y6I, NCGC00016522-05, NCGC00016522-10, [4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate, CAS-603-50-9, DSSTox_CID_2681, 4,4'-(2-pyridylmethylene)bisphenol diacetate, DSSTox_RID_76689, DSSTox_GSID_22681, Q-200726, Q-200727, (pyridin-2-ylmethylene)di-4,1-phenylene diacetate, SR-01000000233, 4-[(4-acetyloxyphenyl)-2-pyridylmethyl]phenyl acetate, 4,4'-(pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate, Bisacodyle, Spirolax, CCRIS 8864, Bisacodyl [USP:INN:BAN:JAN], Bisacodyl [USAN:INN:BAN:JAN], Bisacodyl,(S), Dulcolax (TN), Prestwick_780, Feen-a-Mint Tablets, Spectrum_000086, HalfLytely (Salt/Mix), Opera_ID_884, AC1L1DKN, Prestwick0_000419, Prestwick1_000419, Prestwick2_000419, Prestwick3_000419, Spectrum2_000149, Spectrum3_000318, Spectrum4_000256, Spectrum5_000898, CHEMBL942, Correctol Tablets, Caplets, D07IEF, NCIChal_000004, NCIMech_000456, cid_2391, REGID_for_CID_2391, SCHEMBL21044, BSPBio_000378, BSPBio_001916, KBioGR_000692, KBioSS_000506, DivK1c_000347, SPECTRUM1500147, SPBio_000258, SPBio_002317, Bisacodyl (JP17/USP/INN), BPBio1_000416, CHEBI:3125, DTXSID1022681, BDBM61400, CTK8F8189, HMS501B09, KBio1_000347, KBio2_000506, KBio2_003074, KBio2_005642, KBio3_001416, EBD8044, MolPort-002-045-454, NINDS_000347, HMS1569C20, HMS1920G21, HMS2090K15, HMS2091O03, HMS2096C20, HMS2235I11, HMS3373L17, HMS3652E04, HMS3713C20, Pharmakon1600-01500147, BCP18567, HY-B0557, KS-00000FS0, ZINC3830321, Tox21_110472, Tox21_200338, CCG-35661, CCG-36442, MFCD00038039, NSC755914, s4047, SBB057015, STK293202, AKOS001599884, Tox21_110472_1, API0001726, CS-2667, DB09020, LS-2218, MCULE-8607347748, NSC-614826, NSC-755914, IDI1_000347, 4,4'-Diacetoxydiphenylpyrid-2-ylmethane, Bisacodyl, active ingredient of Viraplex, NCGC00016522-01, NCGC00016522-02, NCGC00016522-03, NCGC00016522-04, NCGC00016522-06, NCGC00016522-07, NCGC00016522-08, NCGC00016522-09, NCGC00016522-11, NCGC00016522-12, NCGC00023260-03, NCGC00023260-04, NCGC00023260-05, NCGC00023260-06, NCGC00257892-01, AC-24284, AJ-45755, AK116442, AN-46334, AS-15820, NCI60_004954, Q941, SC-18411, ST024745, SBI-0051297.P003, 4,4-(2-Pyridylmethylene)diphenol diacetate, AX8117347, AB00051928, B1898, B5066, FT-0603486, ST24026365, D00245, AB00051928-17, AB00051928_18, AB00051928_19, Bisacodyl, analytical standard, for drug analysis, A832704, Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate, SR-01000000233-2, SR-01000000233-3, (pyridin-2-ylmethanediyl)dibenzene-4,1-diyl diacetate, BRD-K39987650-001-05-0, BRD-K39987650-001-15-9, Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate, Phenol,4'-(2-pyridinylmethylene)bis-, diacetate (ester), [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate, 4-[[4-(acetyloxy)phenyl](2-pyridyl)methyl]phenyl acetate, Bisacodyl, European Pharmacopoeia (EP) Reference Standard, [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] ethanoate, 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate #, Bisacodyl, United States Pharmacopeia (USP) Reference Standard, acetic acid [4-[(4-acetyloxyphenyl)-(2-pyridinyl)methyl]phenyl] ester, Bisacodyl for peak identification, European Pharmacopoeia (EP) Reference Standard, Bisacodyl for system suitability, European Pharmacopoeia (EP) Reference Standard, Dulcolax; 4,4'-(2-Pyridylmethylene)bisphenol diacetate; [4-[(4-Acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate


ID: 1166

chemical graph of compound 1166



InChIKey: KIAIFHTWTMKEDI-XFULWGLBSA-N
SMILES: CCCN1CCC2=C3[C@H]1CC4=C(C3=CC(=C2)O)C(=C(C=C4)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 10069059
synonyms found at PubChem are:
R(-)-TNPA HBr, R(-)-2,10,11-Trihydroxy-N-propylnoraporphine hydrobromide, R(-)-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate, 77630-02-5, EU-0100455, R(-)-2-OH-NPA HBr, SCHEMBL1325232, CHEMBL1613539, CTK8G2717, DTXSID00435151, Tox21_500455, CCG-221759, LP00455, NCGC00261140-01, 79640-85-0, VU0288799-2, R(-)-TNPA HBr; R(-)-2-OH-NPA hydrobromide, SR-01000075372, SR-01000075372-1, R(-)-2,10,11-Thrihydroxy-N-propylnorapomorphine hydrobromide


ID: 1167

chemical graph of compound 1167



InChIKey: KJADKKWYZYXHBB-XBWDGYHZSA-N
SMILES: CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 5284627
synonyms found at PubChem are:
topiramate, Topamax, 97240-79-4, Epitomax, Topamax Sprinkle, Tipiramate, Topiramatum, McN-4853, Tipiramato, Topiramato, Tipiramate [French], Tipiramato [Spanish], Topiramatum [INN-Latin], topiramatum [Latin], Topiramato [INN-Spanish], McN 4853, Topimax, Topomax, Topina, RWJ-17021, Epitoma, Topamac, Topiramic acid, topiramate tablet, RWJ-17021-000, Topiramate (TPM), Topamax (TN), Topiramate [USAN:BAN:INN], UNII-0H73WJJ391, 2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate, C12H21NO8S, Topiramate / Placebo, 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, BRN 5988957, Topiramate (JAN/USAN/INN), CHEBI:63631, USL-255, 0H73WJJ391, RWJ 17021, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate, KS-1122, KW-6485, beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate, DSSTox_CID_3688, DSSTox_RID_77148, DSSTox_GSID_23688, Topiragen, Topax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate, Trokendi XR, Qudexy XR, ((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate, ((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate, [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate, SMR000466325, TOR, CAS-97240-79-4, USL255, HSDB 7531, Sulfamate 7, 3hku, 3lxe, USL 255, Topiramate [USAN:USP:INN:BAN], NCGC00095181-01, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[5,4-b:5',3'-d]pyran-3a-yl]methyl sulfamate, Topamax, Topiramate, Trokendi xr (TN), Cilag brandof topiramate, Ortho brand of topiramate, Spectrum2_001128, CBChromo1_000352, D07VDZ, Janssen brand of topiramate, BIDD:PXR0127, SCHEMBL34631, BSPBio_002306, MLS000759431, MLS001424070, BIDD:GT0854, SPECTRUM1505801, SPBio_000995, CHEMBL220492, FRU009, GTPL6849, DTXSID8023688, BDBM10887, KJADKKWYZYXHBB-XBWDGYHZSA-N, MolPort-001-615-062, HMS1922H06, HMS2051L09, HMS2093D20, HMS2232H21, HMS3715I12, Pharmakon1600-01505801, ACT09031, ALBB-022457, HY-B0122, Tox21_111472, Tox21_302401, 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, KM3440, MFCD00865320, NSC759251, s1438, ZINC95616603, AKOS000424547, Topiramate 1.0 mg/ml in Acetonitrile, Topiramate, >=98% (HPLC), solid, Tox21_111472_1, API0004451, CCG-100940, CS-1885, DB00273, MCULE-9403222429, NC00190, NSC-759251, NCGC00178714-01, NCGC00178714-04, NCGC00255221-01, AN-14917, CC-35104, CPD000466325, KB-61804, LS-69764, SAM001246601, SC-16371, SBI-0206907.P001, AB0007831, AB1009630, LS-187392, TL8006021, C07502, D00537, AB00639961-06, AB00639961-08, AB00639961_09, AB00639961_10, 240T794, C-20295, SR-01000759409, W-60376, 5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, beta, Q-201845, SR-01000759409-4, Z1522553470, 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate, 2,3:4,5-di-o-isopropylidene-(beta)-d-fructopyranose sulfamate, Topiramate, United States Pharmacopeia (USP) Reference Standard, 2,3:4,5-Bis-O-(1-methylethylidene)-?-D-fructopyranose sulfamate, 2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate, 2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate, beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material, Beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI), [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0;{2,6}]dodecan-6-yl]methyl sulfamate, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate


ID: 1168

chemical graph of compound 1168



InChIKey: KJFMBFZCATUALV-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)OC2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 4764
synonyms found at PubChem are:
phenolphthalein, 77-09-8, Phthalimetten, Euchessina, Phthalin, Espotabs, Phenolax, Purgophen, Koprol, Laxogen, Trilax, Purga, Lilo, Spulmako-lax, Chocolax, Feen-A-Mint Gum, Purgen, 3,3-Bis(4-hydroxyphenyl)phthalide, Ex-Lax, Fenolftalein, Correctol, Alophen, Doxidan, Medilax, Colax, Laxin, FemiLax, Dihydroxyphthalophenone, Phillips Gelcaps, 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone, Lax-Pills, Evac-Q-Kwik, Evac-Q-Tabs, Evac-Q-Kit, Evac-U-Gen, 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-, Fenolftaleina, Phenolphtaleine, Phenophthalein, Laxcaps, Agoral, Doxan, Fenolftalein [Czech], Phenolphthaleinum, 3,3-Bis(p-hydroxyphenyl)phthalide, 3,3-Bis(4-hydroxyphenyl)isobenzofuran-1(3H)-one, Evac-V-Lax, NCI-C55798, Feen-A-Mint Laxative Mints, Fenolftaleina [INN-Spanish], Phenolphtaleine [INN-French], Phenolphthaleinum [INN-Latin], alpha-Di(p-hydroxyphenyl)phthalide, 3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3H)-one, UNII-6QK969R2IF, NSC 10464, component of Agoral, Phthalide 3,3,-bis(p-hydroxyphenyl)-, CCRIS 6266, HSDB 4161, 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one, EINECS 201-004-7, BRN 0284423, CHEMBL63857, AI3-09081, MLS000069592, 6QK969R2IF, CHEBI:34914, KJFMBFZCATUALV-UHFFFAOYSA-N, component of Correctol, NCGC00018200-07, SMR000059015, 3,3-bis(4-hydroxyphenyl)isobenzofuran-1-one, DSSTox_CID_1125, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, alpha-(p-Hydroxyphenyl)-alpha-(4-oxo-2,5-cyclohexadien-1-ylidene)-o-toluic acid, DSSTox_RID_75956, DSSTox_GSID_21125, 3,3-bis(4-hydroxyphenyl)-3-hydroisobenzofuran-1-one, component of Feen-A-Mint Pills, Laxettes, Phthalide 3,-bis(p-hydroxyphenyl)-, Feen-a-mint, CAS-77-09-8, Phenolphthalein Solution, Alcoholic 1.0%, WLN: T56 BVO DHJ D- D-/R DQ 2, 1(3H)-Isobenzofuranone,3-bis(4-hydroxyphenyl)-, 3, 3-Bis(p-hydroxyphenyl)-1(3H)-isobenzofuranone, Phenolphthalein [INN:BAN], phenolphtalein, Figsen, Laxett es, Phenolphthalein [USP:INN:BAN], Doxan (Salt/Mix), Phenolphthalein,white, Agoral (Salt/Mix), Modane (TN), Phenolphthalein,(S), Laxcaps (Salt/Mix), Phenolphthalein,yellow, Yellow phenolphthalein, PubChem7084, Phenolphthalein (INN), Spectrum_001077, AC1L1IWH, Opera_ID_1337, Spectrum2_001279, Spectrum3_000888, Spectrum4_000982, Spectrum5_001268, Modane Plus (Salt/Mix), D03FDT, EC 201-004-7, Phenolphthalein ACS reagent, PHENOLPHTHALEIN, ACS, cid_4764, Phenolphthalein, ACS reagent, SCHEMBL27670, BSPBio_002518, KBioGR_001383, KBioSS_001557, Phenolphthalein, pH indicator, 5-18-04-00188 (Beilstein Handbook Reference), MLS001148397, BIDD:ER0202, DivK1c_000929, Phenolphthalein, ACS 100g, SPECTRUM1500480, Phenolphthalein Paper, DAB 6, SPBio_001278, AC1Q78Q2, ARONIS002962, DTXSID0021125, BCBcMAP01_000174, HMS502O11, KBio1_000929, KBio2_001557, KBio2_004125, KBio2_006693, KBio3_001776, KS-00000YJD, Phenolphthalein solution, 0.1 N, MolPort-001-011-548, NINDS_000929, HMS1920H04, HMS2091P06, HMS2236I09, HMS3374P06, LS-47, Pharmakon1600-01500480, component of Correctol (Salt/Mix), HY-D0211, KS-00003W2P, NSC10464, ZINC3831317, Phenolphthalein, p.a., ACS reagent, Tox21_110838, Tox21_202219, Tox21_300282, BBL002030, BDBM50077844, CCG-39112, MFCD00005913, NSC-10464, NSC215214, NSC757271, PHENOLPHTHALEIN U.S.P./N.F., SBB008868, STK029876, AKOS000493033, Tox21_110838_1, CS-8152, DB04824, MCULE-5232154932, NE46883, NSC-215214, NSC-757271, RL04943, IDI1_000929, SMP1_000235, NCGC00018200-01, NCGC00018200-02, NCGC00018200-03, NCGC00018200-04, NCGC00018200-05, NCGC00018200-06, NCGC00018200-08, NCGC00018200-09, NCGC00018200-10, NCGC00018200-12, NCGC00023694-03, NCGC00023694-04, NCGC00023694-05, NCGC00023694-06, NCGC00023694-07, NCGC00254039-01, NCGC00259768-01, AC-14431, AJ-45783, AN-23907, BP-30100, SC-74728, ST072636, SBI-0051481.P003, component of Feen-A-Mint Pills (Salt/Mix), TR-037762, 2-[Bis (4-hydroxyphenyl)methyl]benzoic acid, EU-0082600, FT-0659094, P0094, P0700, P0701, P0702, ST24041105, T8172, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-on, EN300-92962, Phenolphthalein, SAJ first grade, >=97.0%, .alpha., .alpha.-Di(p-hydroxyphenyl)phthalide, 3,3-bis (4-hydroxyphenyl)-2-benzofuran-1-on, C14286, D05456, Phenolphthalein, JIS special grade, >=98.0%, AB00052070_15, SR-01000000112, 3,3-bis[4-Hydroxyphenyl]-1-[3H]-isobenzofuranone, I01-9729, I06-1896, Q-201555, SR-01000000112-2, TRANSGENIC MODEL EVALUATION (PHENOLPHTHALEIN), 3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3H)-one #, 3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one, 3,3-bis[4-Hydroxyphenyl]-1-[3H]- isobenzofuranone, BRD-K19227686-001-02-0, BRD-K19227686-001-12-9, Phenolphthalein solution, 1 % (w/v), pH 7.8-10.0, Z57233591, F0921-4309, TRANSGENIC MODEL EVALUATION II (PHENOLPHTHALEIN), Phenolphthalein solution, 0.04 % (w/v), pH 7.8-10.0, Phenolphthalein solution, 0.1 % (w/v), pH 7.8-10.0, Phenolphthalein solution, 0.5 wt. % in ethanol: water (1:1), Phenolphthalein, United States Pharmacopeia (USP) Reference Standard, 390417-24-0, 467-29-8, 546094-13-7, 57214-20-7, InChI=1/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22, Phenolphthalein, ACS reagent, reag. Ph. Eur., indicator, 98-102% (calc. to the dried substance), S. No.: 879, Phenolphthalein, puriss., meets analytical specification of Ph??Eur., BP, 98-101% (calc. to the dried substance)


ID: 1169

chemical graph of compound 1169



InChIKey: KJHHAPASNNVTSN-KPKJPENVSA-N
SMILES: COC1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 641818
synonyms found at PubChem are:
4'-Methoxychalcone, 959-23-9, 1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, (2E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, (E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, CHEMBL34398, 1-(4-methoxyphenyl)-3-phenyl-2-propen-1-one, ST059919, UNII-BM45N45FIZ, (E)-1-(4-Methoxy-phenyl)-3-phenyl-propenone, AF-961/00496034, 2-propen-1-one, 1-(4-methoxyphenyl)-3-phenyl-, (2E)-, 2-Propen-1-one, 1-(4-methoxyphenyl)-3-phenyl-, 22966-19-4, BM45N45FIZ, 4/'-Methoxychalcone, methoxychalcone, 4'-, Styryl p-anisyl ketone, 4' - Methoxychalcone, rarechem am uc 0609, Spectrum5_000236, (E)-4'-Methoxychalcone, 4'-methoxychalcone 97%, AC1LD3N5, BSPBio_002861, SPECTRUM211475, 4-Methoxyphenyl styryl ketone, MEGxp0_001883, ACon1_000177, 4'-Methoxychalcone, 97% 5g, KJHHAPASNNVTSN-KPKJPENVSA-N, MolPort-000-473-981, MolPort-019-724-211, NSC37157, ZINC4175546, ZX-AT024193, 2-benzylidene-4'-methoxyacetophenone, 4482AF, BBL001822, BDBM50141532, LMPK12120188, NSC-37157, SBB012444, STK831846, AKOS001325034, CCG-214164, MCULE-9150634071, SDCCGMLS-0066535.P001, ACM22966194, NCGC00095535-01, NCGC00095535-02, NCGC00095535-03, NCGC00095535-04, CC-19765, TS-00699, 1-(4-Methoxy-phenyl)-3-phenyl-propenone, AB0093160, KB-147403, TR-038586, A-7217, AB00375841-02, E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, SR-05000002481, 1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (6), SR-05000002481-1, BRD-K09233738-001-04-4, InChI=1/C16H14O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-12H,1H3/b12-7


ID: 1170

chemical graph of compound 1170



InChIKey: KJQFBVYMGADDTQ-CVSPRKDYSA-N
SMILES: CCCCS(=N)(=O)CC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 119565
synonyms found at PubChem are:
L-Buthionine-sulfoximine, l-buthionine sulfoximine, 83730-53-4, (2S)-2-Amino-4-(butylsulfonimidoyl)butanoic acid, L-Buthionine-(S,R)-sulfoximine, l-buthionine(s,r)-sulfoximine, L-BSO, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-, NSC 326231, L-Buthionine (SR)-sulfoximine, Buthionine-S,R-sulfoximine, L-, L-Buthionine-(S,R)-sulphoximine, Buthionine sulfoximine, L-, AC1Q6THM, (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic Acid, BUTHIONINE SULFOXIME, NCIMech_000342, AC1L3P1K, Lopac0_000221, SCHEMBL62034, CHEMBL261642, D,L-Buthionine-S,R-sulfoximine, CHEBI:94288, MolPort-002-559-281, HMS3260N03, BSO, Tox21_500221, MFCD00067000, 1-beta-DL-Buthionine(S,R)sulfoximine, AKOS027320570, LP00221, MCULE-5971306528, NSC-326231, KS-00000Y54, NCGC00093690-01, NCGC00093690-02, NCGC00093690-03, NCGC00260906-01, L-Buthionine-sulfoximine, >=97% (TLC), EU-0100221, FT-0627738, B 2515, SR-01000075712, SR-01000075712-1, BRD-A47706533-001-01-8, UNII-EEY8DZS103 component KJQFBVYMGADDTQ-JKYUHCHBSA-N, UNII-LW4108Q0BV component KJQFBVYMGADDTQ-JKYUHCHBSA-N, (R*,S*)-(+-)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid, Butanoic acid, 2-amino-4-((R)-S-butylsulfonimidoyl)-, (2S)-rel-, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (R*,S*)-(+-)-, 97590-40-4, AC1LU7IX, 2-amino-4-(S-butylsulfonimidoyl)butanoate, (2S)-2-ammonio-4-(S-butylsulfonimidoyl)butanoate, (2S)-2-azaniumyl-4-(butylsulfonimidoyl)butanoate


ID: 1171

chemical graph of compound 1171



InChIKey: KJQFBVYMGADDTQ-UHFFFAOYSA-N
SMILES: CCCCS(=N)(=O)CCC(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Goepp" "D Rotin" "E Matthes" "GW Carlile" "DY Thomas" "JW Hanrahan" "SD Macknight" "R Robert" "B Kus" "J Liao"


CID is 21157
synonyms found at PubChem are:
BUTHIONINE SULFOXIMINE, 5072-26-4, DL-Buthionine-[S,R]-sulfoximine, Buthionine sulfoxamine, Buthionine sulphoximine, Buthione sulfoximine, Buthionine-S,R-sulfoximine, 2-Amino-4-(S-butylsulfonimidoyl)butanoic acid, Butionine sulfoximine, 2-Amino-4-(butylsulfonimidoyl)butanoic acid, DL-Buthionine-sulfoximine, NSC 381100, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, BRN 2367136, DL-Buthionine-S,R-sulfoximine, CHEBI:28714, DL-Buthionine-(S,R)-sulfoximine, D,L-Buthionine-(S,R)-sulfoximine, DL-butathionine-(S,R)-sulfoximine, Sulfoximine, S-(3-amino-3-carboxypropyl)-S-butyl-, NSC326231, NSC381100, S-butyl-DL-homocysteine (S,R)-sulfoximine, S-Butyl-DL-homocysteine-[S,R]-sulfoximine, 2-amino-4-(S-butylsulfonimidoyl)butyric acid, NSC 326231, 71765-30-5, C8H18N2O3S, L-Buthionine (SR)-sulfoximine, Buthionine-S,R-sulfoximine, L-, L-Buthionine-(S,R)-sulphoximine, dl-buthionine (s,r)-sulfoximine, BSO, beta-Glutamylcysteine, AC1L2HQW, D0K8LM, Lopac0_000231, SCHEMBL62033, BSPBio_002464, SPECTRUM1505108, CHEMBL1256575, CHEMBL1627290, DTXSID6044434, CTK8F8906, OR9025T, KJQFBVYMGADDTQ-UHFFFAOYSA-N, MolPort-001-770-865, HMS3260P03, BCP24029, BCP27775, KS-000018ET, ZX-AT019574, Tox21_500231, MFCD00070309, S-(n-butyl)homo cysteine sulfoximine, STL328818, AKOS022106364, API0009406, CCG-204326, DB12870, LP00231, MCULE-8178742509, NSC-381100, NCGC00015148-03, NCGC00015148-04, NCGC00015148-05, NCGC00015148-06, NCGC00015148-07, NCGC00093696-01, NCGC00093696-02, NCGC00093696-03, NCGC00260916-01, LS-46081, LS-46082, NCI60_002827, EU-0100231, FT-0624379, ST51012445, 2-Amino-4-(butylsulfonimidoyl);butanoic acid, DL-Buthionine-sulfoximine, >=99.0% (TLC), 2-Amino-4-(butylsulfonimidoyl)butanoic acid #, 2-Amino-4-(S-butylsulfoninidoyl)butanoic acid, 2-Amino-4-(S-butylsulphonimidoyl)butanoic acid, B 2640, C04543, S-(3-Amino-3-carboxypropyl)-S-butylsulphoximine, SR-01000075713, SR-01000075713-1, (S)-2-Amino-4-((R)-butylsulfonimidoyl)butanoic acid, BRD-A04020513-001-01-9, 2-amino-4-[butyl(imino)oxo-|E6-sulfanyl]butanoic acid, AC1MS6SH, D0Z6VR, 2-azaniumyl-4-(butylsulfonimidoyl)butanoate


ID: 1172