CandActCFTR Seed Compounds

The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.

ID: 1001

InChIKey: ITRJWOMZKQRYTA-RFZYENFJSA-N
SMILES: CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5745
synonyms found at PubChem are:
CORTISONE ACETATE, Cortisone 21-acetate, 50-04-4, Cortone acetate, Incortin, Biocort acetate, Artriona, Cortadren, Scheroson, Cortisyl, Adreson, Irisone acetate, Cortelan, Cortistab, Ricortex, Corlin, Cortogen acetate, Compound E acetate, Cortisone monoacetate, Cortisone, 21-acetate, NSC 49420, Cortisone (acetate), Cortilen, UNII-883WKN7W8X, 11-Dehydro-17-hydroxycorticosterone-21-acetate, Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, CCRIS 3661, 11-Dehydro-17-hydroxycorticosterone acetate, EINECS 200-006-5, 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate, 883WKN7W8X, CHEBI:3897, Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate, ITRJWOMZKQRYTA-RFZYENFJSA-N, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione, 21-Acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4, 21-Acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione, NCGC00021191-07, 4-Pregnene-17,alpha,21-diol-3,11,20-trione 21-acetate, DSSTox_CID_2858, DSSTox_RID_76761, DSSTox_GSID_22858, 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate, 21-Acetoxy-4-pregnen-17alpha-ol-3,11,20-trione, 17,21-Dihydroxypregn-4-ene-3,11,20-trione-21-acetate, 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate, CAS-50-04-4, [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate, [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate, 2-((1S,10S,11S,15S,2R,14R)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0 .0<2,7>.0<11,15>]heptadec-6-en-14-yl)-2-oxoethyl acetate, 2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate, SMR000059124, Cortisone acetate (Cortone), Cortisone acetate [USP:JAN], cortison acetate, Cortisone acetate [USAN:JAN], Acetate cortisone, Cortisyl artriona, component of Neosone, Neosone (Salt/Mix), Cortisone-21-acetate, Cortone acetate (TN), D0X4RS, AC1L1L1N, AC1Q62MF, SCHEMBL4501, CHEMBL1650, Lopac0_000271, MLS000069478, MLS002207136, MLS002548859, ARONIS24358, Cortisone acetate (JP17/USP), DTXSID0022858, CTK8D6790, Cortisone 21-acetate, >=99%, MolPort-002-507-122, HMS2235D24, HMS3259N19, HMS3260H04, BCP08487, NSC49420, ZINC3875334, Tox21_113482, Tox21_500271, BDBM50455157, HY-17461A, LMST02030120, MFCD00003609, NSC-49420, SBB080776, AKOS005267225, Tox21_113482_1, AC-6827, AN-9606, CCG-204366, CS-1742, DB01380, LP00271, MCULE-8390750975, NC00677, NCGC00021191-03, NCGC00021191-06, NCGC00021191-08, NCGC00021191-09, NCGC00260956-01, AK163492, AS-13692, CC-25981, LS-55003, ST075179, AB2000655, EU-0100271, FT-0665176, S2559, ST24046370, C 3130, C08173, D00973, J10115, AB00384283-08, AB00384283_09, 003C609, C-21758, W-105993, BRD-K86161929-001-13-3, Pregn-4-ene-3,20-trione, 21-(acetyloxy)-17-hydroxy-, 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate #, 21-Acetoxy-17.alpha.-hydroxy-3,11,20-triketopregnene-4, 21-Acetoxy-17.alpha.-hydroxypregn-4-ene-3,11,20-trione, 4-Pregnen-17.alpha.,21-diol-3,11,20-trione 21-acetate, 4-Pregnene-17alpha,21-diol-3,11,20-trione 21-acetate, Pregn-4-ene-3,20-trione, 17,21-dihydroxy-, 21-acetate, 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 4-Pregnene-17.alpha.,21-diol-3,11,20-trione 21-acetate, Cortisone acetate, European Pharmacopoeia (EP) Reference Standard, Cortisone acetate, United States Pharmacopeia (USP) Reference Standard, 29253-51-8

ID: 1002

InChIKey: ITTLFOBZASCCRH-UHFFFAOYSA-N
SMILES: CC1=C(OC2=CC=CC=C2C1=O)C3=CC=C(C=C3)Br

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 11847486
synonyms found at PubChem are:
CHEMBL2235764

ID: 1003

InChIKey: IUEDHIHMVPHMPR-UHFFFAOYSA-M
SMILES: C1=CC=C(C=C1)C2=CC=[N+](C=C2)C3=CC=CC=C3CO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10494271

ID: 1004

InChIKey: IUIHYYSAVUBPQO-UHFFFAOYSA-N
SMILES: CC1=CCC2=C(C=C3C(=C2O)C(=O)C=C(O3)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3646533
synonyms found at PubChem are:
PTAEROXYLIN, 14729-11-4, Pteroxylin, KBio2_001574, AC1MUTUT, Spectrum_001094, SpecPlus_000014, Spectrum2_000283, Spectrum3_000092, Spectrum4_000933, Spectrum5_001677, BSPBio_001644, KBioGR_001486, KBioSS_001574, SPECTRUM100513, DivK1c_006110, SCHEMBL801404, SPBio_000186, CHEMBL1527943, KBio1_001054, KBio2_004142, KBio2_006710, KBio3_000744, CHEBI:108592, CCG-39841, SDCCGMLS-0066325.P001, NCGC00095423-01, NCGC00095423-02, NCGC00179124-01, SR-05000002509, SR-05000002509-1, 5-hydroxy-2,8-dimethyl-6,9-dihydro-4H-oxepino[3,2-g]chromen-4-one, 5-hydroxy-2,8-dimethyl-6,9-dihydropyrano[3,2-h][1]benzoxepin-4-one

ID: 1005

InChIKey: IUMQXQJZIHWLIN-HSZRJFAPSA-N
SMILES: COC(=O)[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6604858
synonyms found at PubChem are:
SB 218795, 174635-53-1, SB-218795, Sb218795, CHEMBL9843, methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate, Methyl (2R)-phenyl{[(2-phenyl-4-quinolinyl)carbonyl]amino}acetate, SB 218795R, Tocris-1376, NK-3 antagonists, SB, AC1O7GYW, NK-2 antagonists, GSK, D02CCA, Lopac0_000624, MLS000862187, GTPL5764, SCHEMBL4459316, CHEBI:93066, CTK8E8576, IUMQXQJZIHWLIN-HSZRJFAPSA-N, MolPort-003-959-628, HMS2231I18, HMS3261N10, HMS3267B22, NK-3 antagonists, GlaxoSmithKline, ZINC601874, Tox21_500624, BDBM50051289, AKOS024456559, API0007579, CCG-204712, LP00624, SB 218795 R, NCGC00025131-01, NCGC00025131-02, NCGC00025131-03, NCGC00025131-04, NCGC00261309-01, SMR000326950, KB-297292, RT-015641, SB-244487, SK-797230, EU-0100624, S 8817, SR-01000075910, SR-01000597578, J-011022, SR-01000075910-1, SR-01000597578-1, BRD-K61097567-001-03-6, (-)-(R)-N-(|A-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide, (-)-(R)-N-(alpha-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide, (R)-[[2-Phenyl-4-quinolinyl)carbonyl]amino]-methyl ester benzeneacetic acid, (R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester, Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphaR)-

ID: 1006

InChIKey: IUWVALYLNVXWKX-UHFFFAOYSA-N
SMILES: CCCCOC(=O)C1=CC=C(C=C1)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2482
synonyms found at PubChem are:
Butyl 4-aminobenzoate, butamben, 94-25-7, Butesin, Butylcaine, Butyl aminobenzoate, Butesine, Butoform, Planoform, Scuroform, Scuroforme, Butyl keloform, BUTYL P-AMINOBENZOATE, 4-(Butoxycarbonyl)aniline, N-Butyl p-aminobenzoate, Benzoic acid, 4-amino-, butyl ester, 4-Aminobenzoic Acid n-Butyl Ester, n-Butyl-p-aminobenzoate, 4-Aminobenzoic acid butyl ester, Benzoic acid, p-amino-, butyl ester, p-Aminobenzoic acid butyl ester, Butsein, Butyl PABA, NSC 128464, UNII-EFW857872Q, CCRIS 5891, 4-amino butylbenzoate, p-Aminobenzoic acid, butyl ester, HSDB 4245, Butylester kyseliny p-aminobenzoove, EINECS 202-317-1, 4-Aminobenzoic acid butyl, BRN 1211465, AI3-02284, Butylester kyseliny p-aminobenzoove [Czech], MLS000028721, CHEBI:3231, IUWVALYLNVXWKX-UHFFFAOYSA-N, EFW857872Q, NSC128464, CAS-94-25-7, NCGC00016353-03, SMR000059139, DSSTox_CID_2417, DSSTox_RID_76583, DSSTox_GSID_22417, butanylcaine, zyljectin, butamben(usp), Butamben [USAN], Butamben [USAN:USP], SR-01000721933, butambene, Butamben (USP), Prestwick_994, Butesin (TN), Butyl4-aminobenzoate, butyl -4-aminobenzoate, Spectrum_000025, n-butyl 4-aminobenzoate, Opera_ID_633, SpecPlus_000829, Prestwick0_000761, Prestwick1_000761, Prestwick2_000761, Prestwick3_000761, Spectrum2_000850, Spectrum3_001848, Spectrum4_000832, Spectrum5_001496, ACMC-209rr0, WLN: ZR DVO4, 4-amino-benzoicacibutylester, AC1L1DS2, AC1Q2X8Y, AC1Q2X8Z, AC1Q66VZ, SCHEMBL81735, BSPBio_000802, BSPBio_003236, KBioGR_001403, KBioSS_000385, KSC486O9H, MLS002303044, BIDD:ER0674, DivK1c_000838, DivK1c_006925, SPECTRUM1500767, SPBio_000839, SPBio_002741, BPBio1_000884, CHEMBL127516, DTXSID7022417, CTK3I6793, HMS502J20, KBio1_000838, KBio1_001869, KBio2_000385, KBio2_002953, KBio2_005521, KBio3_002736, KS-00000IIO, MolPort-001-790-585, NINDS_000838, p-Aminobenzoic acid n-butyl ester, HMS1570I04, HMS1921G20, HMS2092K06, HMS2097I04, HMS2234M07, HMS3372C17, HMS3714I04, Pharmakon1600-01500767, HY-B1430, ZINC1530937, Tox21_110392, Tox21_200378, ANW-40234, CCG-40317, MFCD00017112, NSC757433, s4583, SBB007542, STL169355, AKOS000119787, Tox21_110392_1, CS-4822, DB11148, LS-1960, MCULE-6283966699, NE10776, NSC-128464, NSC-757433, RP25248, RTR-030885, TRA0052007, IDI1_000838, NCGC00016353-01, NCGC00016353-02, NCGC00016353-04, NCGC00016353-05, NCGC00016353-06, NCGC00016353-08, NCGC00091154-01, NCGC00091154-02, NCGC00091154-03, NCGC00091154-04, NCGC00257932-01, AC-13349, AJ-26712, AN-42682, BC206116, CJ-05219, CJ-24059, DS-13802, PARA-AMINOBENZOIC ACID BUTYL ESTER, ST059627, SBI-0051887.P002, DB-029553, KB-189278, TR-030885, 4CH-023767, A0270, AB00052407, FT-0617559, ST24046262, C07875, D00730, AB00052407_12, AE-641/05573061, I01-6155, Q-200433, SR-01000721933-2, SR-01000721933-3, BRD-K27217864-001-04-1, BRD-K27217864-001-05-8, BRD-K27217864-001-15-7, Z57126994, F2190-0449, Butamben, United States Pharmacopeia (USP) Reference Standard, degrees +/-+/-(1/2) paragraph sign inverted exclamation marko yen

ID: 1007

InChIKey: IVOMOUWHDPKRLL-HMEJCUHCSA-N
SMILES: C1[C@@H]2[C@@H](C([C@@H](O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6714006
synonyms found at PubChem are:
Prestwick0_001092, Prestwick1_001092, Prestwick2_001092, AC1O8Q0A, SPBio_003052, SCHEMBL14575138, HMS1571K06, AKOS015964989, (-)-Adenosine 3',5'-cyclic monophosphate, (4aR,6R,7aR)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

ID: 1008

InChIKey: IVVNZDGDKPTYHK-UHFFFAOYSA-N
SMILES: CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4826
synonyms found at PubChem are:
pinacidil, (R,S)-Pinacidil, 60560-33-0, (+-)-Pinacidil, Pinacidilum, 85371-64-8, Pinacidilum [INN-Latin], Pinacidil anhydrous, P 1134, (+/-)-Pinacidil, Pinacidil (anhydrous), EINECS 262-294-9, S 1230, S-1230, N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine, CHEMBL1159, MLS000069377, 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine, 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine, Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, SMR000058360, P-154, 2-Cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)guanidine monohydrate, Guanidine, 2-cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)-, monohydrate, Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, monohydrate, Pinacidil [INN], SR-01000075340, SR-05000001757, NCGC00025188-04, 1-cyano-3-(4-pyridyl)-2-(1,2,2-trimethylpropyl)guanidine, Prestwick_396, ACMC-20mijl, Spectrum_000387, SpecPlus_000759, AC1Q4SLP, Opera_ID_1844, Prestwick0_000246, Prestwick1_000246, Prestwick2_000246, Prestwick3_000246, Spectrum2_001739, Spectrum5_001372, D02KMO, AC1L1J1H, CBiol_001878, Lopac0_001037, SCHEMBL65787, BSPBio_000032, BSPBio_001461, BSPBio_002360, KBioGR_000181, KBioSS_000181, KBioSS_000867, MLS002154248, DivK1c_006855, SPECTRUM2300270, SPBio_001818, SPBio_002251, BPBio1_000036, GTPL2412, SCHEMBL9260276, DTXSID7048249, Guanidine, N-cyano-N'-4-pyridinyl-N''-[(1R)-1,2,2-trimethylpropyl]-, BCBcMAP01_000050, BDBM86245, CHEBI:91706, CTK5F4813, KBio1_001799, KBio2_000181, KBio2_000867, KBio2_002749, KBio2_003435, KBio2_005317, KBio2_006003, KBio3_000361, KBio3_000362, IVVNZDGDKPTYHK-UHFFFAOYSA-N, Bio1_000164, Bio1_000653, Bio1_001142, Bio2_000181, Bio2_000661, HMS1361J03, HMS1568B14, HMS1791J03, HMS1922L10, HMS1989J03, HMS2089C19, HMS2094G21, HMS2095B14, HMS2234F10, HMS3263O15, HMS3267P10, HMS3371H14, HMS3402J03, HMS3712B14, Pharmakon1600-02300270, 113563-71-6, 85371-64-8 (Parent), NSC_4826, Tox21_501037, 2657AH, BDBM50103517, BDBM50240750, CCG-39493, NSC759588, AKOS001637331, AKOS025394868, API0008270, CCG-205115, CCG-222341, LP01037, MCULE-2402591602, NSC-759588, IDI1_033931, NCGC00015787-02, NCGC00015787-03, NCGC00015787-04, NCGC00015787-05, NCGC00015787-06, NCGC00025188-02, NCGC00025188-03, NCGC00025188-05, NCGC00025188-06, NCGC00025188-07, NCGC00025188-08, NCGC00095199-01, NCGC00095199-02, NCGC00095199-03, NCGC00095199-04, NCGC00188958-01, NCGC00247667-01, NCGC00261722-01, AN-35700, BC202316, KB-79743, LS-73486, SBI-0051008.P004, CAS_85371-64-8, RT-004885, EU-0101037, FT-0630932, AB00052442-04, AB00052442_05, AB00052442_06, 371P648, 560P330, SR-01000075340-1, SR-01000075340-3, SR-05000001757-1, SR-05000001757-2, BRD-A43882281-001-06-4, BRD-A43882281-001-11-4, BRD-A58207013-001-01-2, 3-cyano-2-(3,3-dimethylbutan-2-yl)-1-pyridin-4-ylguanidine, N-cyano-N'-(4-pyridyl)-N''-(1,2,2-trimethylpropyl)guanidine, (+/-)-N-Cyano-N'-4-pyridinyl-N"-(1,2,2-trimethylpropyl)guanidine, 2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine, N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine, ()-N-Cyano-N''-4-pyridinyl-N''''-(1,2,2-trimethylpropyl)guanidine, (Z)-2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine, 4N-cyanoimino(1,2,2-trimethylpropylamino)methyl-4-pyridinamine(Pinacidil), 4N-cyanoimino[1,2,2-trimethyl-(1R)-propylamino]methyl-4-pyridinamine, 4N-cyanoimino[1,2,2-trimethyl-(1S)-propylamino]methyl-4-pyridinamine, N''''-cyano-N-pyridin-4-yl-N''-[(1R)-1,2,2-trimethylpropyl]guanidine, N''''-cyano-N-pyridin-4-yl-N''-[(1S)-1,2,2-trimethylpropyl]guanidine, N-Pyridin-4-yl-N''-(1,2,2-trimethyl-propyl)-cyanoguanidine (pinacidil), ( inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine, (inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine, Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, hydrate (1:1), N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine ((+)-pinacidil), N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine (Pinacidil), 113563-69-2

ID: 1009

InChIKey: IVYPNXXAYMYVSP-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3712
synonyms found at PubChem are:
Indole-3-carbinol, 700-06-1, 3-Indolemethanol, (1H-Indol-3-yl)methanol, INDOLE-3-METHANOL, 1H-indol-3-ylmethanol, 1H-Indole-3-methanol, 3-Hydroxymethylindole, 3-Indolylcarbinol, Indinol, 3-Indole methanol, Indole 3 carbinol, 3-(Hydroxymethyl)indole, (1H-Indol-3-yl)-methanol, CCRIS 3261, I3C, UNII-C11E72455F, EINECS 211-836-2, 1H-Indol-3-Yl-Methanol, C9H9NO, NSC 525801, BRN 0121323, AI3-60090, CHEBI:24814, IVYPNXXAYMYVSP-UHFFFAOYSA-N, Prevention 4 (indole-3-carbinol), IN1455, C11E72455F, NCGC00090701-06, indol-3-ylmethan-1-ol, I0496, SMR000385784, I3C cpd, 3-Indolecarbinol, 3-Indolylmethanol, indole-3-carbinole, Indole-3-carbinol;3-Indole methanol, zlchem 356, 3-Hydroxymethylindoll, PubChem7265, 3-hydroxymethyl indole, AC1L1GJH, Spectrum2_001710, Spectrum3_001973, ACMC-209oc7, AC1Q7C3V, DSSTox_CID_11458, DSSTox_RID_78876, DSSTox_GSID_31458, BSPBio_003573, MLS001333161, MLS001333162, SCHEMBL195520, SPECTRUM1505320, SPBio_001700, 3-Indolemethanol, 97% 1g, CHEMBL155625, 1H-Indole-3-methanol (9CI), DTXSID7031458, CTK5D1676, GTPL10047, KBio3_002949, ZLC0198, MolPort-000-139-921, HMS1789O22, HMS2235E10, HMS3369B02, HMS3651I18, ZINC158743, ACN-S002804, ACT03591, BCP00087, HY-N0170, INDOLE-3-CARBINOL (I3C), KS-000008ZG, Tox21_400055, 9344AF, AM1155, ANW-35813, CCG-38786, HSCI1_000097, MFCD00005632, NSC525801, s2313, SBB004095, AKOS001075120, AC-7583, AN-8864, CS-7780, DB12881, GS-0916, LS-2173, LS20980, MCULE-6344603304, NSC-525801, RP01522, RTC-020178, SDCCGMLS-0065970.P001, SDCCGMLS-0065970.P002, VI30396, Indole-3-methanol (Indole-3-carbinol), SMP2_000172, TRA-0190502, NCGC00090701-01, NCGC00090701-02, NCGC00090701-03, NCGC00090701-04, NCGC00090701-05, NCGC00090701-07, AJ-15333, BC226969, BR-53373, CAS-700-06-1, CJ-01822, KB-52660, SC-06380, SY015976, ZB007051, AB0008317, AB1009801, KB-143577, KB-183011, KB-202551, ST2402099, TL8004925, 4CH-018038, A9256, FT-0615875, ST50308202, 00I061, I-2100, M-3233, A836732, SR-01000838318, I10-0077, SR-01000838318-3, BRD-K01815685-001-02-3, BRD-K01815685-001-07-2, Z85923165

ID: 1010

InChIKey: IWALGNIFYOBRKC-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1330
synonyms found at PubChem are:
1,3-Dipropyl-8-p-sulfophenylxanthine, 89073-57-4, DPSPX, 1,3-Dipropyl-8-(4-sulfophenyl)xanthine, 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid, CHEMBL418333, Benzenesulfonic acid,4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-, PSPX, 4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)benzenesulfonic acid, 1,3-Dspx, 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-benzenesulfonic acid, ACMC-20ccmd, Lopac-A-022, AC1L1B8N, AC1Q6X0U, Lopac0_000145, MLS002153336, SCHEMBL1321892, CTK5G2512, DTXSID70237528, IWALGNIFYOBRKC-UHFFFAOYSA-N, HMS2231H19, HMS3260M12, HMS3374O06, ZINC9229228, Tox21_500145, BDBM50018162, AKOS027320584, CCG-204240, LP00145, VZ20604, 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)benzenesulfonic acid, 1,3-Dipropyl-8-(p-sulfophenyl)xanthine, NCGC00015001-01, NCGC00015001-02, NCGC00015001-03, NCGC00015001-04, NCGC00093635-01, NCGC00093635-02, NCGC00260830-01, SMR000326868, LS-191127, A-022, EU-0100145, FT-0606724, 1,3-Dipropyl-8-(p-sulfophenyl)xanthine, powder, C-21569, SR-01000075228, SR-01000075228-1, 4-(1,3-dipropyl-2,3,6,7-tetrahydro-2,6-dioxo-1H-purin-8-yl)benzenesulfonic acid, 4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid, Benzenesulfonic acid, 4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-, 4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid:1/4 moles H2O

ID: 1011

InChIKey: IWAWCPZVTXCFKD-UHFFFAOYSA-N
SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 168993
synonyms found at PubChem are:
Pizotifen malate, Pizotyline malate, 5189-11-7, Pizotifen (malate), Sanomtgran, Mosegor, Litec malate, Pizotifen hydrogen malate, Sandomigran malate, Sandomygran malate, BC 105 malate, C19H21NS.C4H6O5, CHEBI:50213, EINECS 225-970-4, Pizotifen maleate, Sandomigran (TN), Q-201591, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxysuccinate, Malic acid, compound with 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine (1:1), Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, malate (1:1), SR-05000001896, litec; malic acid, Mosegor (TN), Sandomigran;pizotyline, AC1Q5VDI, Prestwick0_000992, Prestwick1_000992, Prestwick2_000992, Prestwick3_000992, AC1L52XC, BSPBio_001083, SCHEMBL365598, SPECTRUM1505003, SPBio_002974, BPBio1_001193, CHEMBL1592663, CTK1H0133, HY-B0115A, MolPort-002-507-853, HMS1571G05, HMS2093G20, HMS2098G05, HMS3651C11, HMS3715G05, Pharmakon1600-01505003, 2661AH, NSC758899, s1394, AKOS015907762, CCG-213329, CS-1871, NSC-758899, Sandomigran, pizotyline, 5189-11-7, NCGC00096062-01, NCGC00096062-02, AS-10171, AB2000084, LS-115014, D08397, 189P117, I14-2724, SR-05000001896-1, SR-05000001896-3, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine 2-hydroxybutanedioate, 9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene malate (1:1), Butanedioicacid, 2-hydroxy-, compd. with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine(1:1), Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-,malate (1:1)

ID: 1012

InChIKey: IWDBEHWZGDSFHR-BTJKTKAUSA-N
SMILES: CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5358812
synonyms found at PubChem are:
Methiothepin maleate, METITEPINE MALEATE, 19728-88-2, CHEBI:64202, NSC281816, 8-Methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate, 1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine maleate, MLS000756636, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine (2Z)-but-2-enedioate, 20229-30-5, SR-01000075560, Prestwick_739, LVP2XBC3GA, UNII-LVP2XBC3GA, AC1NSD6U, SPECTRUM1503637, SCHEMBL2048660, CHEMBL1358918, DTXSID8042630, HMS502N15, AOB6250, MolPort-003-666-493, HMS1569K11, HMS2096K11, HMS3713K11, Pharmakon1600-01503637, BG0375, CCG-39505, NSC759875, AKOS024458571, NSC-281816, NSC-759875, ACM19728882, NCGC00095921-01, AS-16941, SR-01000075560-7, SR-01000075560-8, 1-[10,11-Dihydro-8-(methylthio)dibenzo(Z)[b,f]thiepin-10-yl]-4-methylpiperazine maleate, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine maleate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine maleate, (.+-.)-Metitepine maleate,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (.+-.)-, (Z)-2-butenedioate (1:1), (Z)-but-2-enedioic acid; 1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine, 1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium (2Z)-but-2-enedioate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine (2Z)-but-2-enedioate, 1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium (2Z)-but-2-enedioate, Piperazine,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (+)-, (Z)-2-butenedioate (1:1)

ID: 1013

InChIKey: IWSWDOUXSCRCKW-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 44383
synonyms found at PubChem are:
Terazosin hydrochloride, 63074-08-8, Terazosin HCl, Hytrin, Vasocard, Abbott-45975, Zayasel, Terazosin hydrochloride anhydrous, (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochloride, MLS000040261, SMR000044015, DSSTox_CID_25493, DSSTox_RID_80913, DSSTox_GSID_45493, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride, 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride, CAS-63074-08-8, 63590-64-7 (Parent), SR-01000000197, Prestwick_146, terazosine hydrochloride, Tetrazosin hydrochloride, Opera_ID_398, AC1L2BPY, NCGC00016903-01, SCHEMBL41545, MLS001077301, MLS001305722, C19H25N5O4.HCl, CHEMBL1256665, DTXSID7045493, KS-00000JKM, IWSWDOUXSCRCKW-UHFFFAOYSA-N, MolPort-003-666-790, HMS1570G04, Pharmakon1600-01505576, BCP12795, Terazosin monohydrochloride anhydrous, Tox21_110674, NSC759168, s4679, AKOS007930686, Tox21_110674_1, AC-2074, CCG-220751, LP01138, NE45355, NSC-759168, TRA0127916, VA11840, TERAZOSIN HYDROCHLORIDE (anhydrous), NCGC00016026-10, NCGC00094404-01, NCGC00094404-02, AN-14324, DS-11401, AB1009460, AB2000463, DB-018541, LS-110235, TL8004930, TR-037527, EU-0101138, FT-0605647, V1531, T 4680, Terazosin hydrochloride, >=98% (TLC), powder, 074T088, I06-0651, SR-01000000197-2, SR-01000000197-4, SR-01000000197-12, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride, 2[4-(Tetrahydro-2-furoy1)piperazinyl]-4-amino-6,7-dimethoxyquinazoline hydrochloride, 4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride, [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone hydrochloride, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine Hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-,monohydrochloride, AC1LD8ZY, AKOS026749822, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone; hydron; chloride, MolPort-000-768-720, MCULE-4508839187

ID: 1014

InChIKey: IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES: C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 37542
synonyms found at PubChem are:
ribavirin, 36791-04-5, Tribavirin, Virazole, Rebetol, Ribavirine, Copegus, Vilona, Ribamide, Ribamidil, Ribasphere, Viramid, Ribamidyl, Ribavirina, Ribavirinum, Rebetron, Varazid, RTCA, Ribavirin Capsules, Ribavirine [INN-French], Ribavirinum [INN-Latin], Ribavirina [INN-Spanish], ICN-1229, Rebretron, Ribovirin, Viramide, Virazid, Virazide, Ribav, 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, Cotronak, Ravanex, Ribacine, Ribavirin [USAN:INN], C-Virin, DRG-0028, Ribasphere (TN), Virazole (TN), 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, Copegus (TN), Rebetol (TN), UNII-49717AWG6K, Ribavirin (Copegus), 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide, HSDB 6513, SCH 18908, RBV, BRN 0892462, Ribavarin, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide, CHEBI:63580, 49717AWG6K, RG-964, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide, Ro-20-9963, Virazole (Ribavirin) Inhalation Solution, 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, R-964, DSSTox_CID_3557, EN300-59237, Ro 20-9963/000, NSC 163039, R 9644, DSSTox_RID_77081, DSSTox_GSID_23557, RTC, 1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-, 1-(beta-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide, 1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide, 1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide, 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, SMR000058315, SR-01000076112, Ribavirine;, NSC163039, Drug: Ribavirin, KS-1104, Ribavirin [USAN:USP:INN:BAN], Drug: Ribavirin, Ribavirin,(S), NCGC00015904-02, Ribavirin, antiviral, CAS-36791-04-5, Vilona (TN), PubChem14187, Spectrum_001826, 4pb1, ribofluranosyl carboxamide, AC1L1XXZ, AC1Q1IDC, AC1Q4ZGS, Prestwick3_000993, Spectrum3_001876, Spectrum4_001252, Spectrum5_002075, 1-|A-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, D0DI8X, D0H3WI, SCHEMBL3727, CHEMBL1643, Ribavirin (JAN/USP/INN), Lopac0_001063, BSPBio_001085, BSPBio_003352, KBioGR_001804, KBioSS_002331, cid_37542, MLS000028486, MLS002222317, DivK1c_000782, SPECTRUM1503938, Ribavirin (JP17/USP/INN), BPBio1_001195, GTPL6842, DTXSID8023557, CTK7J7594, HMS502H04, KBio1_000782, KBio2_002328, KBio2_004896, KBio2_007464, KBio3_002854, BIB6306, IWUCXVSUMQZMFG-AFCXAGJDSA-N, MolPort-002-507-104, NINDS_000782, HMS2090L15, HMS2094O09, HMS2098G07, HMS2232P07, HMS3263E08, HMS3715G07, Pharmakon1600-01503938, BB_NC-00567, HY-B0434, ZINC1035331, Tox21_110259, Tox21_200967, Tox21_501063, BDBM50154375, CCG-38985, MFCD00058564, NSC758650, s2504, AKOS001715163, Tox21_110259_1, API0004062, CS-2540, DB00811, GS-3572, LP01063, LS-1241, MCULE-9495128592, NSC-758650, IDI1_000782, SMP1_000261, NCGC00090726-01, NCGC00090726-03, NCGC00090726-04, NCGC00090726-05, NCGC00090726-06, NCGC00090726-07, NCGC00090726-08, NCGC00090726-09, NCGC00090726-12, NCGC00258520-01, NCGC00261748-01, AJ-24715, AK-49185, AS-34178, BR-49185, CC-34249, CPD000058315, SAM002548967, SC-12159, ZB015662, BCP0726000138, SBI-0051033.P003, AB0068936, AX8005387, ST2413783, AB00430481, EU-0101063, FT-0082885, FT-0630597, FT-0649908, R0077, D00423, J10190, M-7546, AB00430481-15, AB00430481-16, AB00430481_17, AB00430481_18, RBI034 (2-5A antisense compound) + Ribavirin, 1-beta-Ribofuranosyl-1,2,4-triazole-3-carboamide, 791R045, AA-504/07617051, C-14783, SR-01000721904, SR-01000076112-2, SR-01000076112-3, SR-01000076112-4, SR-01000721904-2, BRD-K60369935-001-02-7, BRD-K60369935-001-18-3, SR-01000076112-11, 1-?-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, Ribavirin, British Pharmacopoeia (BP) Reference Standard, Z1522567185, 1-(beta -D-ribofuranosyl)-1,2,4-triazole-3-carboxamide, Ribavirin, European Pharmacopoeia (EP) Reference Standard, Ribavirin, United States Pharmacopeia (USP) Reference Standard, Ribavirin, Pharmaceutical Secondary Standard; Certified Reference Material, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,2,4-triazole-3-carboxamide, 437710-49-1, 66510-90-5

ID: 1015

InChIKey: IWVTXAGTHUECPN-ANBBSHPLSA-N
SMILES: CCOC(=O)OC(C)OC(=O)[C@H]1C(S[C@H]2N1C(=O)[C@H]2NC(=O)[C@@H](C3=CC=CC=C3)N)(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 441398
synonyms found at PubChem are:
Bacampicillin hydrochloride, bacampicillin HCl, 37661-08-8, Bacampicillin (hydrochloride), Spectrobid, Bacampicillin hydrochoride, BAPC, Ambacamp, Ambaxin, Bacacil, Velbacil, CHEBI:2969, Penglobe, DSSTox_CID_25466, DSSTox_RID_80897, DSSTox_GSID_45466, EINECS 253-580-4, Spectrobid (TN), C21H27N3O7S.HCl, (2S,5R,6R)-6-((R)-(2-Amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ester with ethyl 1-hydroxyethyl carbonate, monohydrochloride, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1-((ethoxycarbonyl)oxy)ethyl ester, monohydrochloride, (2S-(2alpha,5alpha,6beta(S*)))-, Prestwick_776, Bacampicillin hydrochloride [USAN:USP:JAN], NCGC00016837-01, SureCN721373, AC1L9B3G, CAS-37661-08-8, MLS002153801, SCHEMBL124593, CHEMBL1200965, DTXSID0045466, HY-B1149A, IWVTXAGTHUECPN-ANBBSHPLSA-N, MolPort-019-996-595, HMS1569C14, 1-((Ethoxycarbonyl)oxy)ethyl (2S-(2alpha,5alpha,6beta(S*)))-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrochloride, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, 1-((ethoxycarbonyl)oxy)ethyl ester, hydrochloride, 50972-17-3 (Parent), Tox21_110640, AKOS016014246, Tox21_110640_1, API0000413, CCG-220416, CS-4754, Bacampicillin hydrochloride (JP17/USP), NCGC00179582-03, SMR001233177, AX8020538, C08123, D00927, A823813, (2S,5R,6R)-6-[[(2R)-2-amino-1-oxo-2-phenylethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 1-ethoxycarbonyloxyethyl ester hydrochloride, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride, 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-7-oxidanylidene-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride, 1-[(ethoxycarbonyl)oxy]ethyl 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate hydrochloride

ID: 1016

InChIKey: IXORZMNAPKEEDV-OBDJNFEBSA-N
SMILES: C[C@@]12[C@H](C=C[C@@]3([C@@H]1[C@@H]([C@]45[C@H]3CC[C@](C4)(C(=C)C5)O)C(=O)O)OC2=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6466
synonyms found at PubChem are:
GIBBERELLIC ACID, 77-06-5, Gibberellin A3, Gibberellin, Gibreskol, Brellin, Cekugib, Grocel, Gibberellin X, Gibberellic acid GA3, Gib-Tabs, Pro-Gibb, Pro-Gibb Plus, Gib-Sol, Gibberellins A4A7, Gibefol, Regulex, Activol GA, Pgr-iv, Acide gibberellique, Gibberellins, Berelex, Gibberellinsaeure, UNII-BU0A7MWB6L, GA3, Gibrescol, Ryzup, (+)-Gibberellic Acid, Acide gibberellique [ISO-French], NCI-C55823, BU0A7MWB6L, Gibbrel, Gibberellic acid [BSI:ISO], AI3-52922, CHEBI:28833, IXORZMNAPKEEDV-OBDJNFEBSA-N, Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1alpha,2beta,4aalpha,4bbeta,10beta)-, Caswell No. 467, NCGC00091033-01, DSSTox_CID_656, 2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone, DSSTox_RID_75715, Gibb-3-ene-1,10-dicarboxylic acid, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, DSSTox_GSID_20656, (1alpha,2beta,4aalpha,4bbeta,10beta)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone, (3S,3aR,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propenoazuleno(1,2-b)furan-4-carboxylic acid, (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid, (3S,3aS,4S,4aS,6S,8aS,8bS,11S)-6,11-Dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid, (3S,3aS,4S,4aS,7S,9aR,9bR,12S)-7,12-Dihydroxy-3-methyl-6-methylene-2-oxoperhydro-4a,7-methano-9b,3-propeno(1,2-b)furan-4-carboxylic acid, 2beta,4aalpha,7-Trihydroxy-1beta-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, 2beta,4alpha,7-Trihydroxy-1-methyl-8-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, 2beta,4alpha,7-Trihydroxy-1-methylene-4aalpha,4bbeta-gibb-3-ene-1alpha,10beta-dicarboxylic acid 1,4a-lactone, Gibberelic acid, CCRIS 4820, HSDB 712, EINECS 201-001-0, GIBERELLIN, NSC 14190, EPA Pesticide Chemical Code 043801, GIBERILLIC ACID, BRN 0054346, (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno(1,2-b)furan-4-carboxylic acid, 2,4alpha,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10 beta-dicarboxylic acid 1,4alpha-lactone, GIBBERELLIC ACID, 90%, GA [Plant Growth Regulator], Gibberellic acid [ISO:BSI], NSC14190, NSC19450, Gibberellin Acid, 4psb, 2,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-carboxylic acid 1-4-lactone, CAS-77-06-5, Gibberellin (GA), Gibb-3-ene-1, 2,4a,7-trihydroxy-1-methyl-8-methylene-, 1,4a-lactone, (1.alpha.,2.beta.,4a.alpha.,4b.beta.,10.beta.)-, Spectrum_000628, 4q0k, SpecPlus_000148, PS49_SUPELCO, Prestwick0_000965, Prestwick1_000965, Prestwick2_000965, Prestwick3_000965, Spectrum2_000311, Spectrum3_001301, Spectrum4_001444, Spectrum5_000027, gibberellic acid (ga-3), bmse000317, SCHEMBL15577, BSPBio_000969, BSPBio_002961, KBioGR_001927, KBioSS_001108, 5-18-09-00269 (Beilstein Handbook Reference), MLS001055447, MLS002154076, DivK1c_006244, G7645_SIGMA, SPBio_000302, SPBio_002890, BPBio1_001067, MEGxm0_000440, CHEMBL1232952, DTXSID0020656, ACon0_000224, ACon1_000551, BCBcMAP01_000012, KBio1_001188, KBio2_001108, KBio2_003676, KBio2_006244, KBio3_002181, U - 1,2-Dibromoethane solution, MolPort-003-931-014, HMS1571A11, HMS2098A11, HMS2231J16, HMS3039M06, (1S,2S,4aR,4bR,7S,9aS,10S,10aR)-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid, ZINC3860467, 125-67-7 (mono-potassium salt), Tox21_202052, Tox21_303023, MFCD00079329, NSC-14190, NSC-19450, AKOS024464812, AKOS025310145, CCG-208472, EBD2198547, SMP1_000136, NCGC00091033-02, NCGC00091033-03, NCGC00091033-04, NCGC00091033-05, NCGC00091033-06, NCGC00091033-09, NCGC00256446-01, NCGC00259601-01, AN-23906, AS-14216, K339, NCI60_000922, SC-11963, SMR000686070, SMR001233386, AB00513979, ST24047329, Gibberellin, 80% gibberellin A3 basis (TLC), 079G329, Gibberellic acid, 90% gibberellin A3 basis (HPLC), Gibberellic acid, PESTANAL(R), analytical standard, BRD-K92758126-001-05-5, BRD-K92758126-001-06-3, BRD-K92758126-001-17-0, 6F94D8A8-3230-4AB5-93C1-46F5E84FE343, Gibberellic acid, United States Pharmacopeia (USP) Reference Standard, Gibberellic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-Dihydroxy-11-methyl-6-methylene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-13-ene-9-carboxylic acid, (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1(5,8).0(1,10).0(2,8)]heptadec-13-ene-9-carboxylic acid, 1405-96-5, 16202-20-3, 192662-67-2, 295313-57-4, 2beta,7alpha-dihydroxy-1beta-methyl-8-methylidene-13-oxo-4a,1alpha-epoxymethano-4aalpha,4bbeta-gibb-3-ene-10beta-carboxylic acid, 474760-45-7, 58915-44-9, 7121-55-3, 859282-71-6, Gibberellic acid, plant cell culture tested, BioReagent, >=90% gibberellin A3 basis (of total gibberellins.)

ID: 1017

InChIKey: IXWZKSIVLFEQNZ-UHFFFAOYSA-N
SMILES: C(C1=CC=C([NH0+](=O)[OH0-])S1)1C(C(=O)OCC2=CC=CC=C2)=C(C)NC(C)=C1C(=O)OCC1=CC=CC=C1

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazzei" "MT Mazzei" "F Cateni" "M Giampieri" "N Pedemonte" "P Fossa" "LJ Galietta" "M Zacchigna"

CID is 46227522
synonyms found at PubChem are:
CHEMBL604890

ID: 1018

InChIKey: IYBDWVUOOFQLSF-LLPMONEMSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C3[C@@]1(C45C(O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)(C(=O)C=CC2(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708584
synonyms found at PubChem are:
KBio2_006302, ISOGEDUNIN, Spectrum_000686, SpecPlus_000169, Spectrum2_001895, Spectrum3_001337, Spectrum4_001332, Spectrum5_000203, BSPBio_003093, KBioGR_001823, KBioSS_001166, SPECTRUM100195, DivK1c_006265, SPBio_001830, SCHEMBL13424846, KBio1_001209, KBio2_001166, KBio2_003734, KBio3_002313, CCG-38468, SDCCGMLS-0066306.P001, NCGC00178301-01, BRD-A52326238-001-02-3

ID: 1019

InChIKey: IYBQHJMYDGVZRY-UHFFFAOYSA-N
SMILES: CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6314
synonyms found at PubChem are:
Lidocaine hydrochloride, 73-78-9, LIDOCAINE HCL, Lidothesin, Xyloneural, Lignocaine hydrochloride, Laryng-O-jet, Lidocaine (hydrochloride), Xilina hydrochloride, Lidocaton, Xylocard, Rucaina hydrochloride, Xycaine hydrochloride, Xylotox hydrochloride, Duncaine hydrochloride, Isicaine hydrochloride, Lidocain hydrochloride, Anestacon hydrochloride, Gravocain hydrochloride, Leostesin hydrochloride, Xylocaine hydrochloride, Xylocitin hydrochloride, Lidothesin hydrochloride, Xylestesin hydrochloride, LIDOCAINE VISCOUS, LTA II KIT, UNII-EC2CNF7XFP, PEDIATRIC LTA KIT, LARYNG-O-JET KIT, XYLOCAINE PRESERVATIVE FREE, EC2CNF7XFP, EINECS 200-803-8, LARYNGOTRACHEAL ANESTHESIA KIT, 2-Diethylamino-2',6'-acetoxylidide hydrochloride, XYLOCAINE 4% PRESERVATIVE FREE, Lidocaine hydrochloride anhydrous, Linocaine hydrochloride, Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride, XYLOCAINE 5% W/ GLUCOSE 7.5%, MLS000069665, S 202, V 262, XYLOCAINE 1.5% W/ DEXTROSE 7.5%, alpha-Diethylamino-2,6-acetoxylidine hydrochloride, N-(Diethylaminoacetyl)-2,6-dimethylaniline hydrochloride, omega-Diethylamino-2,6-dimethylacetanilide hydrochloride, SMR000058468, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride, ALPHACAINE HCL, Glydo, 2',6'-ACETOXYLIDIDE, 2-(DIETHYLAMINO)-, HYDROCHLORIDE, LIDOCAINE HCL VISCOUS, Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride (1:1), 137-58-6 (Parent), CHEBI:50512, LIDOCAINE HCL PRESERVATIVE FREE, SR-01000000189, LIDOCAINE HCL IN PLASTIC CONTAINER, LIDOCAINE HCL 0.2% IN DEXTROSE 5%, LIDOCAINE HCL 0.4% IN DEXTROSE 5%, LIDOCAINE HCL 5% AND DEXTROSE 7.5%, ALPHACAINE HYDROCHLORIDE, Lidocaine hydrochloride viscous, Diethylamino-2,6-dimethylacetanilide Hydrochloride, lidocaine hydrochloride(jan/usp), Dalcaine (TN), LIDOCAINE HCL PRESERVATIVE FREE IN PLASTIC CONTAINER, Prestwick_296, LIDOCAINE HCL 0.2% IN DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.4% IN DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.8% IN DEXTROSE 5% IN PLASTIC CONTAINER, lidocainehydrochloride, LIDOCAINE HCL 0.1% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.2% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER, LIDOCAINE HCL 0.8% AND DEXTROSE 5% IN PLASTIC CONTAINER, Lidoca ne hydrochloride, Lidocaine hydrochloride preservative free, Lidocaine(hydrochloride), Opera_ID_351, Lidocaine hydrochloride in plastic container, Lidocaine hydrochloride 0.2% in dextrose 5%, Lidocaine hydrochloride 0.4% in dextrose 5%, Lidocaine hydrochloride 5% and dextrose 7.5%, AC1Q5LY0, C14H22N2O.HCl, Lidocaine injection (JP17), SPECTRUM1500689, AC1L1M96, CHEMBL541521, DTXSID4058782, CTK8G0579, HY-B0185A, IYBQHJMYDGVZRY-UHFFFAOYSA-N, MolPort-003-666-319, HMS1568I21, HMS1921C22, Lidocaine hydrochloride preservative free in plastic container, Pharmakon1600-01500689, Lidocaine Hydrochloride (anhydrous), Lidocaine hydrochloride (JAN/USP), KS-00001F6P, Lidocaine hydrochloride 0.2% in dextrose 5% in plastic container, Lidocaine hydrochloride 0.4% in dextrose 5% in plastic container, Lidocaine hydrochloride 0.8% in dextrose 5% in plastic container, Tox21_500669, CCG-39281, Lidocaine hydrochloride 0.1% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.2% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.4% and dextrose 5% in plastic container, Lidocaine hydrochloride 0.8% and dextrose 5% in plastic container, NSC757420, s4667, (unlabeled)Lidocaine-d6 Hydrochloride, AKOS015889456, API0003175, CS-3888, LP00669, NSC-757420, NCGC00094030-01, NCGC00094030-02, NCGC00094030-03, NCGC00094030-04, NCGC00094030-05, NCGC00261354-01, AC-11712, AK326167, AS-35171, BC203198, LS-13898, EU-0100669, FT-0603276, D02086, L 5647, A837924, I01-2012, I01-4416, Q-201304, SR-01000000189-3, SR-01000000189-9, 2',6'-Acetoxylidide, 2-(diethylamino)-, monohydrochloride, 2',6'-Acetoxylidide, 2-(diethylamino)-, monohydrochloride (8CI), 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide hydrochloride, AC1LCW7O, SCHEMBL29129, EBD952442, AKOS026750038, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide; hydron; chloride, Alphacaine N, Alphacaine SP, N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide hydrochloride

ID: 1020

InChIKey: IYETZZCWLLUHIJ-UTONKHPSSA-N
SMILES: C[C@H](CC1=CC=CC=C1)N(C)CC#C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 26758
synonyms found at PubChem are:
Selegiline hydrochloride, 14611-52-0, Eldepryl, Zelapar, Selegiline Hcl, (-)-Deprenyl hydrochloride, l-Deprenyl hydrochloride, Jumex hydrochloride, Eldepryl hydrochloride, Zydis selegiline, (-)-Deprenil hydrochloride, (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride, (-)-E-250 hydrochloride, UNII-6W731X367Q, L-Deprenyl, HSDB 7183, FPF1100, R-(-)-Deprenyl (hydrochloride), (-)-Phenylisopropylmethylpropynylamine, Otrasel, 6W731X367Q, (-)-(R)-N,alpha-Dimethyl-N-2-propynylphenethylamine hydrochloride, (-)-N,alpha-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride, (-)-(R)-N,alpha-Dimethyl-N-2-propynylphenethylamine monohydrochloride, DSSTox_CID_24584, DSSTox_RID_80331, DSSTox_GSID_44584, (R)-(-)-N,alpha-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride, Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, hydrochloride, (R)-, CHEBI:9087, CPD000449328, SMR000449328, C13H17N.HCl, SR-01000597928, R-(-)-Deprenyl hydrochloride, Plurimen, Seledat, Vivapryl, Xilopar, Ensam, 14611-51-9 (Parent), (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride, CCRIS 8571, Selegiline hydrochloride [USAN], L-deprenyl HCl, L-Deprenalin HCl, Eldepryl (TN), Prestwick_846, Selegiline hydrochloride [USAN:USP], E-250, NCGC00016708-01, D0J2MJ, D0OH5I, D0Y8AN, AC1L1BU2, CAS-14611-52-0, R-(-)deprenyl hydrochloride, SCHEMBL41392, MLS000758294, MLS001423947, MLS002153281, MLS002222269, CHEMBL1200904, DTXSID9044584, (R)-(-)-Deprenyl hydrochloride, IYETZZCWLLUHIJ-UTONKHPSSA-N, HMS1569P05, FPF-1100, Selegiline hydrochloride (JAN/USP), Tox21_110572, Tox21_301846, BG0405, AKOS005166822, Tox21_110572_1, API0004151, CCG-100773, CS-2764, KS-5098, NC00023, NC00605, NCGC00024994-06, NCGC00255797-01, AC-18759, CC-34395, HY-14199, LS-30157, SAM001246969, SAM002589926, AX8151001, FT-0601539, ST24035592, KS-00000059, D00785, K-4669, 611S520, SR-01000597928-1, SR-01000597928-5, SR-01000597928-6, R-(-)-Deprenyl hydrochloride, powder, >=98% (HPLC), UNII-63G7R4955A component IYETZZCWLLUHIJ-UTONKHPSSA-N, Selegiline Hydrochloride 1.0 mg/ml in Methanol (as free base), (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine hydrochloride, (R)-(-)-N-?-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride, (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-aminehydrochloride, Selegiline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Selegiline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 40602-63-9, N-methyl-N-[(1R)-1-methyl-2-phenylethyl]prop-2-yn-1-aminium chloride, (-)-( R)- N,a-Dimethyl- N-2-propynylphenethylamine hydrochloride

ID: 1021

InChIKey: IYGYMKDQCDOMRE-ZWKOTPCHSA-N
SMILES: CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10237
synonyms found at PubChem are:
(+)-Bicuculline, bicuculline, d-Bicuculline, 485-49-4, Bicculine, Bicucullin, Bicuculline (+), UNII-Y37615DVKC, NSC 32192, C20H17NO6, EINECS 207-619-7, BRN 0098786, CHEBI:3092, CHEMBL417990, Y37615DVKC, (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one, NSC32192, Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-, (6R)-6-((5S)-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxolano[4,5-g]isoquinolin-5- yl))-6-hydro-2H-1,3-dioxoleno[4,5-e]isobenzofuran-8-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one, (R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one, SR-01000075252, Bicuculline,(+), Prestwick_96, Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-((5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (6R)-, Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (6R)-, AC1L1URW, Prestwick0_000589, Prestwick1_000589, Prestwick2_000589, Prestwick3_000589, Biomol-NT_000252, D00LBX, (+)-Bicuculline, 98%, SCHEMBL8222, Lopac0_000234, BSPBio_000438, 4-27-00-06900 (Beilstein Handbook Reference), MLS002153892, DivK1c_000609, SPBio_002657, BPBio1_000482, BPBio1_000794, GTPL2312, DTXSID3042687, HMS501O11, KBio1_000609, AOB5192, MolPort-001-728-112, NINDS_000609, HMS1569F20, HMS2096F20, HMS2235H18, HMS3266A07, HMS3652N20, BCP04180, HY-N0219, BDBM50000693, MFCD00005006, NSC-32192, PDSP2_000138, s7071, ZINC19899011, AKOS024282673, API0002224, CCG-204329, CS-5493, DB11562, IDI1_000609, NCGC00017385-06, (+)-Bicuculline, >=97.0% (TLC), 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one, AN-45228, AS-17471, LS-70680, SC-17991, SMR001233241, ST057559, ST057706, AB0019776, FT-0080946, N1592, V0271, B 9130, C09364, 485B494, C-21058, SR-01000075252-1, SR-01000075252-4, SR-01000075252-5, WLN: T C566 DO FO KN EH&&TJ K1 J- ET B565 CVO JO LO EH KHJ, (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-e][1,3]benzodioxol-8-one, (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one, (bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium, (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one, [R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-((5S)-6-methyl-5,6,7,8-tetrahydro-2H-1,3-dioxoleno[4,5-g]isoquinolin-5-yl)-6 -hydro-2H-1,3-dioxoleno[4,5-e]isobenzofuran-8-one, 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one, 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline), 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3'',4'':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline), Furo[3,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [R-(R*,S*)]-, Furo[3,4-e]-1,3-benzodioxol-8(6H)-one,6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (6R)-

ID: 1022

InChIKey: IYNMDWMQHSMDDE-MHXJNQAMSA-N
SMILES: CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O.CC(C)(C)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 441313
synonyms found at PubChem are:
PERINDOPRIL ERBUMINE, 107133-36-8, ACEON, Perindopril tert-butylamine, Perindopril (erbumine), McN-A-2833-109, Perindopril erbumine [USAN], UNII-1964X464OJ, S-9490-3, CHEBI:8025, (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, 1964X464OJ, (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1), Aceon (TN), Covapril, 1H-Indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-, compd. with 2-methyl-2-propanamine (1:1), 2-methylpropan-2-amine (2S,3aS,7aS)-1-(((S)-1-ethoxy-1-oxopentan-2-yl)-L-alanyl)octahydro-1H-indole-2-carboxylate, (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine, C19H32N2O5.C4H11N, AC1L9AYA, Perindopril;Coversyl;Aceon, DSSTox_CID_24198, DSSTox_GSID_44198, SCHEMBL41679, SPECTRUM1505212, CHEMBL1200343, DTXSID1044198, HY-B0130A, Perindopril erbumine (JAN/USP), IYNMDWMQHSMDDE-MHXJNQAMSA-N, MolPort-003-666-611, HMS1922N07, HMS2093M06, Pharmakon1600-01505212, 107133-36-8 (erbumine), Tox21_303915, CCG-39035, CP0070, MFCD02313824, NSC758929, AKOS015841351, AKOS015961912, CS-1904, KS-1243, NSC-758929, NCGC00178276-01, NCGC00357164-01, AC-19078, LS-82690, AB0105687, AB2000130, AX8041142, TL8000252, CAS-107133-36-8, ST24048892, C07707, D00624, 133P368, SR-05000001835, SR-05000001835-1, Perindopril erbumine, United States Pharmacopeia (USP) Reference Standard, Perindopril tert-butylamine, European Pharmacopoeia (EP) Reference Standard, Perindopril for peak identification, European Pharmacopoeia (EP) Reference Standard, Perindopril for stereochemical purity, European Pharmacopoeia (EP) Reference Standard, (2S,3(infinity)S,7(infinity)S)-1-[(S)-N-[(S)-1-Carboxybutyl]alanyl]hexahydro-2-indolinecarboxylic acid, 1-ethyl ester, compound with tert-butylamine (1:1), (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid; 2-methylpropan-2-amine, (2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid--2-methylpropan-2-amine (1/1), (2S,3aS,7aS)-1-{(S)-2-[(S)-1-(ethoxycarbonyl)butylamino]propanoyl}octahydroindole-2-carboxylic acid--1,1-dimethylethanamine (1/1), 1H-indole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydo-, (2S-(1R(R*(R*)),2alpha,3abeta,7abeta))_,compd. With 2-methyl-2-propanamine (1:1)

ID: 1023

InChIKey: IYVFNTXFRYQLRP-VVSTWUKXSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5486699
synonyms found at PubChem are:
Troxerutin, 7085-55-4, Posorutin, Vitamin P4, Troxerutine, Vastribil, Veinamitol, Trioxyethylrutin, Factor P-zyma, Tris(hydroxyethyl)rutin, Veniten, Ruven, Venoruton P4, Tris(hydroxyethyl)rutoside, 3',4',7-Tris(hydroxyethyl)rutin, UNII-7Y4N11PXO8, Pherarutin, Troxerutin (INN), Trihydroxyethylrutin, Veno SL, Rufen-P4, Troksevazin, Troxarutin, Helveton, Venaroid, Flebil, 7Y4N11PXO8, Pur-Rutin, Veinamitol Pulver, Z 6000, Troxarutin-ratiopharm, Troxerutine [INN-French], Troxerutinum [INN-Latin], Troxerutina [INN-Spanish], Troxevazin, Troxerutin [INN:BAN:DCF], CCRIS 1798, Trihydroxyethylrutoside [French], Troxerutina, Troxerutinum, EINECS 230-389-4, 3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside, C33H42O19, BRN 4778232, 7,3',4'-Tris(O-(2-hydroxyethyl)rutin, Trihydroxyethylrutoside, Venoruton gel, TriHER, Troxerutin,(S), NCGC00095147-01, 2-(3,4-Bis(2-hydroxyethoxy)phenyl)-3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-7-(2-hydroxy ethoxy)-4H-1-benzopyran-4-one, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)methyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 3',4',7-Tris[O-(2-hydroxyethyl)]rutin, AC1NUOPY, DSSTox_CID_25929, DSSTox_RID_81230, DSSTox_GSID_45929, SCHEMBL142110, Tris-O-(2-hydroxyethyl)rutin, CHEMBL3182320, DTXSID4045929, Tris-O-(b-hydroxyethyl)rutoside, UNII-808O347B5Y, IYVFNTXFRYQLRP-VVSTWUKXSA-N, MolPort-003-939-710, Flavone, 3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-, 3-(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside), HY-N0139, Tox21_111450, s2369, ZINC85552699, AKOS016339659, Trihydroxyethylrutin, >=80% (HPLC), 808O347B5Y, CS-8204, DB13124, KS-1394, 4H-1-Benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-, K198, 3',4',7-Tri-O-(b-hydroxyethyl)rutoside, CAS-7085-55-4, O-(beta-hydroxyethyl)-tutinosides (mixture), 3,4,7-TRIS-O-(2-HYDROXYETHYL)RUTIN, D07180, rahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 085T554, A837010, BRD-K73529671-001-04-5, Troxerutin, European Pharmacopoeia (EP) Reference Standard, UNII-808O347B5Y component IYVFNTXFRYQLRP-VVSTWUKXSA-N, 12041-99-5, 1260230-02-1, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tet, 2-(3,4-bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxymethyl]-2-oxanyl]oxy]-1-benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one, 2-[3,4-bis(2-hydroxyethyloxy)phenyl]-7-(2-hydroxyethyloxy)-3-[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-oxidanyl-chromen-4-one, 27321-15-9, 288306-51-4, 29702-52-1, 3-[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside]3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-Flavone, 3-[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-delta-glucopyranoside]3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-Flavone, 37396-63-7, 55965-63-4, 68244-17-7, 96304-71-1

ID: 1024

InChIKey: IYYZUPMFVPLQIF-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3S2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3023
synonyms found at PubChem are:
dibenzothiophene, 132-65-0, Diphenylene sulfide, Dibenzo[b,d]thiophene, 9-Thiafluorene, alpha-Thiafluorene, 2,2'-Biphenylylene sulfide, Dibenzo(b,d)thiophene, Dibenzothiophene [USAN], UNII-Z3D4AJ1R48, [1,1'-Biphenyl]-2,2'-diyl sulfide, .alpha.-Thiafluorene, CCRIS 5307, HSDB 7409, NSC 2843, EINECS 205-072-9, (1,1'-Biphenyl)-2,2'-diyl sulfide, AI3-00043, Z3D4AJ1R48, CHEBI:23681, IYYZUPMFVPLQIF-UHFFFAOYSA-N, NCGC00094646-01, Dibenzothiophene (USAN), benzo[b]benzo[b]thiophene, DSSTox_CID_27725, DSSTox_RID_82526, DSSTox_GSID_47741, a-thiafluorene, Dibenzothiophene, analytical standard, CAS-132-65-0, Dibenzthiophene, C12H8S, Dibenzo[b]thiophene, PubChem7382, Spectrum_000926, [1,2'-diyl sulfide, Dibenzothiophene, 98%, AC1L1EZZ, AC1Q1HKJ, Spectrum2_001011, Spectrum3_000383, Spectrum4_000504, Spectrum5_000863, Dibenzothiophene, >=99%, ACMC-1BQ37, SCHEMBL13294, BSPBio_002165, KBioGR_001047, KBioSS_001406, KSC174S9H, BIDD:GT0331, DivK1c_000393, SPECTRUM1500235, SPBio_001161, Dibenzothiophene, 98% 25g, CHEMBL219828, DTXSID0047741, CTK0H4993, HMS501D15, KBio1_000393, KBio2_001406, KBio2_003974, KBio2_006542, KBio3_001385, KS-00000ETF, NSC2843, MolPort-000-153-847, NINDS_000393, HMS1920E12, HMS2091K22, HMS3652N11, Pharmakon1600-01500235, HY-B0973, NSC-2843, ZINC1482032, Tox21_111308, Tox21_303415, ANW-19450, CCG-40229, MFCD00004969, NSC756732, s4205, SBB058907, STK367232, AKOS000278427, Tox21_111308_1, AC-1025, ACN-029847, CS-4462, MCULE-2582244078, NSC-756732, RP24479, RTC-070138, TRA0025307, IDI1_000393, NCGC00094646-02, NCGC00094646-03, NCGC00094646-04, NCGC00257449-01, AJ-26309, AN-15323, AS-12976, BC205510, BR-47299, CJ-05087, CJ-23638, KB-49718, LS-61504, SC-46601, SBI-0051339.P003, DB-042124, ST2412790, TL8000774, AM20050251, D0148, D2474, FT-0622967, ST50825219, Dibenzothiophene 10 microg/mL in Acetonitrile, C20125, D03777, M-4959, AB00051965_02, AB00051965_03, Dibenzothiophene, purified by sublimation, >=99%, SR-05000002089, I09-0207, Q-101161, SR-05000002089-1, Z1250100656, 8-thiatricyclo[7.4.0.0(2),]trideca-1(9),2(7),3,5,10,12-hexaene, 8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene, InChI=1/C12H8S/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8, 83R

ID: 1025

InChIKey: IZEKFCXSFNUWAM-UHFFFAOYSA-N
SMILES: C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3108
synonyms found at PubChem are:
dipyridamole, 58-32-2, Dipyridamine, Persantin, Dipyridamol, Dipyudamine, Persantine, Curantyl, Stimolcardio, Cardoxin, Kurantil, Stenocardil, Cardioflux, Dipiridamol, Dipyridan, Peridamol, Anginal, Apricor, Coribon, Corosan, Coroxin, Stenocardiol, Agilease, Chilcolan, Justpertin, Permiltin, Piroan, Cleridium 150, Coronarine, Gulliostin, Prandiol, Natyl, Prandiol 75, Usaf Ge-12, Dypyridamol, Cleridium, Iv Persantine, Dipyridamolum, Cardoxil, RA 8, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetraethanol, RA-8, Antistenocardin, Dipyramidole, Coridil, Curantil, Protangix, Novo-Dipiradol, Dipiridamol [INN-Spanish], Dipyridamolum [INN-Latin], Permole, Dipyridamole (Persantine), Persantine (TN), UNII-64ALC7F90C, Aggrenox, Apo-Dipyridamole Fc, Apo-Dipyridamole Sc, NSC 515776, MLS000028420, C24H40N8O4, Dipyridamole [USAN:INN:BAN:JAN], EINECS 200-374-7, CHEMBL932, NSC-515776, 2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido(5,4-d)pyrimidine, BRN 0068373, SMR000058382, 64ALC7F90C, CHEBI:4653, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol, IZEKFCXSFNUWAM-UHFFFAOYSA-N, Pyrimido(5,4-d)pyrimidine, 2,6-bis(bis(2-hydroxyethyl)amino)-4,8-dipiperidino-, NSC515776, Ethanol, 2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, CAS-58-32-2, NCGC00015385-12, 2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine, D 9766, 2,2',2'',2'''-((4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol, DSSTox_CID_20668, DSSTox_RID_79531, DSSTox_GSID_40668, 2,2',2'',2'''-((4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetrakis(ethan-1-ol), 2,2',2'',2'''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, Ethanol, 2,2',2'',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Cerebrovase, Dypyridamole, Miosen, 2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine, Apo-Dipyridamole, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetraethano, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, Ethanol, 2,2',2'',2'''-((4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetra-, SR-01000003065, Dipridacot, Prestwick_145, Dipyridamole [USAN:USP:INN:BAN:JAN], Spectrum_001004, Tocris-0691, Opera_ID_494, AC1Q7CXU, AC1Q7CXW, AC1Q7CXX, Prestwick0_000142, Prestwick1_000142, Prestwick2_000142, Prestwick3_000142, Spectrum2_000972, Spectrum3_000402, Spectrum4_000522, Spectrum5_000839, Lopac-D-9766, D0F9GE, UPCMLD-DP072, AC1L1F6T, cid_3108, Permole;Dipyridan;Persantine, Apotex Brand of Dipyridamole, Belmac Brand of Dipyridamole, IPRAD Brand of Dipyridamole, Lopac0_000464, SCHEMBL16119, BSPBio_000244, BSPBio_001554, BSPBio_001924, KBioGR_001123, KBioSS_001484, 4-26-00-03840 (Beilstein Handbook Reference), MLS001076306, MLS001333724, MLS002548866, DivK1c_000696, SPECTRUM1500259, SPBio_001003, SPBio_002183, Ashbourne Brand of Dipyridamole, BPBio1_000270, GTPL4807, Novopharm Brand of Dipyridamole, DTXSID6040668, Thymidine,6-dihydro-6-methoxy-, UPCMLD-DP072:001, BDBM23620, CTK8B5592, Dipyridamole (JP15/USP/INN), Dipyridamole (JP17/USP/INN), HMS502C18, IZEKFCXSFNUWAM-UHFFFAOYSA-, KBio1_000696, KBio2_001484, KBio2_004052, KBio2_006620, KBio3_001144, KS-00000KNA, MolPort-001-792-504, NINDS_000696, BCPP000256, HMS1568M06, HMS1791N16, HMS1920I10, HMS1989N16, HMS2089N15, HMS2091O18, HMS2095M06, HMS2232E19, HMS3259C03, HMS3261M10, HMS3266J17, HMS3371J03, HMS3402N16, HMS3655I20, HMS3712M06, Pharmakon1600-01500259, ZINC643046, BCP26947, Berlin Chemie Brand of Dipyridamole, Berlin-Chemie Brand of Dipyridamole, EBD20789, HY-B0312, Tox21_110133, Tox21_500464, ANW-49242, BBL027781, CCG-40190, MFCD00010555, NSC756743, s1895, STL377790, AKOS000509426, Tox21_110133_1, BCP9000613, CS-2352, DB00975, Dipyridamole, >=98% (TLC), powder, HS-0041, LP00464, MCULE-3112669573, MP-0582, NC00448, NSC-619103, NSC-756743, RTR-020274, VA10749, IDI1_000696, SMP2_000208, NCGC00015385-01, NCGC00015385-02, NCGC00015385-03, NCGC00015385-04, NCGC00015385-05, NCGC00015385-06, NCGC00015385-07, NCGC00015385-08, NCGC00015385-09, NCGC00015385-10, NCGC00015385-11, NCGC00015385-13, NCGC00015385-14, NCGC00015385-15, NCGC00015385-16, NCGC00015385-18, NCGC00023914-02, NCGC00023914-04, NCGC00023914-05, NCGC00023914-06, NCGC00023914-07, NCGC00023914-08, NCGC00023914-09, NCGC00023914-10, NCGC00023914-11, NCGC00261149-01, 4CA-0464, AC-18100, AJ-23813, AN-23600, BAS 00818792, BC213273, BR-76609, CJ-04389, CPD000058382, H843, LS-66732, NCI60_005689, SAM002264609, SC-18455, ST078856, ZB014732, Boehringer Ingelheim Brand of Dipyridamole, SBI-0050449.P004, 2,8-dipiperidinopyrimido[5,4-d]pyrimidine, AB0013300, AB2000355, ST2415551, AB00051974, B1933, D2274, EU-0100464, FT-0603242, Permole, Persantine, Dipyridan, Dipyridamole, W1467, EN300-70723, BIM-0050449.0001, D00302, J10379, 54290-EP2277865A1, 54290-EP2298773A1, 54290-EP2305653A1, 54290-EP2308562A2, AB00051974-18, AB00051974-19, AB00051974_20, AB00051974_21, 58-32-2,763-39-4(XHCl), A828156, SR-01000003065-2, SR-01000003065-4, SR-01000003065-5, SR-01000003065-7, W-105400, BRD-K86301799-001-04-1, BRD-K86301799-001-19-9, BRD-K86301799-001-24-9, Z1259192074, Dipyridamole, British Pharmacopoeia (BP) Reference Standard, Dipyridamole, European Pharmacopoeia (EP) Reference Standard, Dipyridamole, United States Pharmacopeia (USP) Reference Standard, Pyrimido(5, 2,6-bis[bis(2-hydroxyethyl)amino]-4,8-diperidino-, 2,2'',2'''-[4,8-Dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilotetraethanol, 2,2',2'',2'''-(4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilotetraethanol, 2,2',2',2'''-((4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol, 2-[[2-(bis(2-hydroxyethyl)amino)-4,8-di(piperidin-1-yl)pyrimido[6,5-e]pyrimidin-, Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard, Ethanol,2',2'',2'''-(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetra-, WLN: T66 BN DN GN INJ CCN HCN E- AT6NTJ B2Q F2Q& J- AT6NTJ B2Q F2Q, 2,2 ,2 ,2 -(4,8-Dipiperidino- pyrimido [5,4-d] pyrimidine-2,6- diyldinitrilotetraethanol, 2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]-pyrimidine-2,6-diyl)bis(azanetriyl))tetraethanol, 2,2',2'',2'''-(4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl)tetraethanol, 2,2',2'',2'''-(4,8-Dipiperidino-pyrimido [5,4-d] pyrimidine-2,6-diyldinitrilotetraethanol, 2,2',2'',2'''-[(4,8-dipiperidin-1-ylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, 2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, 2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol, 2-({6-[bis(2-hydroxyethyl)amino]-4,8-dipiperidylpyrimidino[5,4-d]pyrimidin-2-y l}(2-hydroxyethyl)amino)ethan-1-ol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(1-piperidinyl)-6-pyrimido[5,4-d]pyrimidinyl]-(2-hydroxyethyl)amino]ethanol, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol;, Ethanol, 2,2',2'',2'''-(4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyldinitrilo)tetra-, Ethanol, 2,2',2',2'''-((4,8-di-1-iperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Ethanol, 2,2',2',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, Ethanol,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, Ethanol,2',2'',2'''-[(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-, Ethanol,2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, InChI=1/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2

ID: 1026

InChIKey: IZHCNQFUWDFPCW-ZJIMSODOSA-N
SMILES: C[C@H](CC1=CN=CN1)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957567
synonyms found at PubChem are:
75614-89-0, Histamine, R(-)-alpha-methyl-, dihydrochloride, (R)-1-(1H-Imidazol-4-yl)propan-2-amine dihydrochloride, R(-)-alpha-Methyl histamine dihydrochloride, 75614-87-8, Alpha-Methylhistamine-R, SR-01000075271, EU-0100618, SCHEMBL1369323, CHEMBL1434496, AOB5644, IZHCNQFUWDFPCW-ZJIMSODOSA-N, Tox21_500618, AKOS027320798, r-alpha-methylhistamine dihydrochloride, CCG-221922, LP00618, NCGC00093992-01, NCGC00261303-01, (R)(-)-|A-Methylhistamine dihydrochloride, FT-0671812, H-128, (R)(−)-|A-Methylhistamine dihydrochloride, SR-01000075271-1, (R)-(-)-a-Methyl-1H-imidazole-4-ethanamine dihydrobromide, (R)(-)-|A-Methyl-1H-imidazole-4-ethanamine dihydrochloride, (R)(-)-alpha-Methylhistamine dihydrochloride, solid, >=98% (HPLC)

ID: 1027

InChIKey: IZMYWEXQNFYSRZ-UHFFFAOYSA-N
SMILES: C1C2C(C(=O)N)=C(NC(C3CCCCC3)=O)SC=2CCC1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"K Du" "AS Verkman" "H Yang" "T Ma" "N Pedemonte" "GL Lukacs" "VS Gopinath" "AA Shelat" "A Taddei" "C Folli" "LJ Galietta" "RK Guy"

CID is 675676
synonyms found at PubChem are:
CHEMBL209562, 2-[(cyclohexylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 142995-02-6, 2-(cyclohexanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, AC1LDUWQ, Cambridge id 6993511, Oprea1_477124, ARONIS001749, SCHEMBL3126680, ZINC38517, IZMYWEXQNFYSRZ-UHFFFAOYSA-N, MolPort-001-501-026, BDBM50185103, STK095320, AKOS000491344, MCULE-4335105668, KS-00003V54, BAS 04054141, ST054630, BB0278962, EU-0008292, UNM000003541001, AK-968/12120287, SR-01000463330, SR-01000463330-1, Z27358490, 2-cyclohexaneamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(Cyclohexanecarbonyl-amino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid amide, 2-(cyclohexanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(cyclohexylcarbonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide

ID: 1028

InChIKey: IZQSVPBOUDKVDZ-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281654
synonyms found at PubChem are:
Isorhamnetin, 480-19-3, 3-Methylquercetin, Isorhamnetol, Quercetin 3'-methyl ether, 3'-Methoxyquercetin, 3'-O-Methylquercetin, 3'-Methoxy-3,4',5,7-tetrahydroxyflavone, isorhamnetine, 3'-Methylquercetin, C.I. 75680, 3-Methylquercetine, UNII-07X3IB4R4Z, CCRIS 3791, 3,4',5,7-Tetrahydroxy-3'-methoxyflavone, 3'-O-Methyl Quercetin, C16H12O7, EINECS 207-545-5, Flavone, 3'-methoxy-3,4',5,7-tetrahydroxy-, BRN 0044723, 3,5,7,4'-Tetrahydroxy-3'-methoxyflavone, 07X3IB4R4Z, CHEBI:6052, CHEMBL379064, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3-methoxy-4-hydroxyphenyl)-3,5,7-trihydroxy-, FLAVONE, 3,4',5,7-TETRAHYDROXY-3'-METHOXY-, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, Q-100518, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one, iso-rhamnetin, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one, SR-05000002256, isorhamentin, Isorhanetin,(S), AC1NQYTP, 3,4',5,7-tetrahydroxy-3'-methoxy-flavone, D07YDN, Oprea1_145406, SCHEMBL19235, MEGxp0_001863, ACon1_000275, BDBM23409, CTK8E4477, Isorhamnetin, analytical standard, KS-00000JEU, DTXSID10197379, IZQSVPBOUDKVDZ-UHFFFAOYSA-N, MolPort-001-742-583, ZINC517261, BCP11534, HY-N0776, Isorhamnetin, >=95.0% (HPLC), CI-259, LMPK12110002, MFCD00017310, SBB067248, AKOS015905141, CCG-208422, CCG-208453, CS-5945, NCGC00163572-01, NCGC00163572-02, NCGC00163572-03, NCGC00180719-01, AC-20263, AN-45180, CC-29718, LS-69023, LS-69043, O276, SC-19267, ZB014262, 3,3',5,7-Tetrahydroxy-3'-methoxyflavone, TR-036851, FT-0603409, N1358, ST50309356, 3'-METHOXY-4',5,7-TRIHYDROXYFLAVONOL, C10084, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl), 480I193, C-19475, SR-05000002256-2, SR-05000002256-3, BRD-K83977206-001-01-4, Isorhamnetin, primary pharmaceutical reference standard, 3,5,7-Trihydroxy-2-(4-hydroxy-3-metoxyphenyl)benzopyran-4-one, Isorhamnetin, United States Pharmacopeia (USP) Reference Standard, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one #, 3 inverted exclamation marka-Methoxy-3,4 inverted exclamation marka,5,7-tetrahydroxyflavone, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)- (9CI)

ID: 1029

InChIKey: IZVFFXVYBHFIHY-SKCNUYALSA-N
SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 65728
synonyms found at PubChem are:
Lathosterol, gamma-Cholesterol, 80-99-9, Cholest-7-en-3-ol, 5alpha-Cholest-7-en-3beta-ol, 7-Cholesten-3-beta-ol, Cholesterin [German], Cholest-7-en-3beta-ol, delta(sup 7)-Cholestenol, 5-alpha-Cholest-7-en-3-beta-ol, Cholest-7-en-3-ol, (3b,5a)-, (3-beta,5-alpha)-Cholest-7-en-3-ol, CHEBI:17168, 7,(5-alpha)-Cholesten-3-beta-ol, 7-Cholesterol, .DELTA.7-Cholestenol, 7-Cholesten-3-.beta.-ol, 5|A-Cholest-7-en-3|A-ol, cholesterol gr, gamma-Cholestenol, cholesta-7-enol, cholest-7-en-ol, Cholesterol Pharma, (7)-Cholestenol, Delta7-Cholestenol, 3.beta.-Hydroxy-5.alpha.-cholest-7-ene, Cholesterol,NF Grade, 7-En-3-cholestanol, cholesterol extra pure, delta(7)-Cholestenol, Cholesterol - synthetic, 3b-Hydroxy-5-cholestene, delta7-Cholesten-3beta-ol, Delta7-cholesten-3-beta-ol, alpha-cholest-7-en-3beta-ol, SCHEMBL187737, (3beta)-Cholest-7-en-3-ol, 5-a-cholest-7-en-3-beta-ol, AC1L23U8, CHEMBL3138639, CTK3E8757, IZVFFXVYBHFIHY-SKCNUYALSA-N, 3|A-Hydroxy-5|A-cholest-7-ene, 3beta-Hydroxy-5alpha,7-cholestene, (3beta,alpha)-Cholest-7-en-3-ol, ZINC4095573, 3beta-Hydroxy-5alpha-cholest-7-ene, (3beta,5alpha)-cholest-7-en-3-ol, LMST01010089, MFCD00056176, (3|A,5|A)-Cholest-7-en-3-ol, AKOS024307570, KS-0000188D, LS-53132, Cholest-7-en-3-ol, (3-beta,5-alpha)-, FT-0631361, C01189, C-43996, Cholest-7-en-3-ol, (3-beta,5-alpha)- (9CI), (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

ID: 1030

InChIKey: IZXSTWMUJGTAMI-UHFFFAOYSA-N
SMILES: CC(C)C1COC2=C(O1)C=C3C=CC(=O)OC3=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3503044
synonyms found at PubChem are:
DIHYDRO-OBLIQUIN, KBio1_001461, Spectrum_001781, SpecPlus_000421, AC1MQK3J, Spectrum2_000350, Spectrum3_000102, Spectrum4_001788, Spectrum5_000435, BSPBio_001684, KBioGR_002337, KBioSS_002263, SPECTRUM100543, DivK1c_006517, SPBio_000419, CHEMBL1610638, SCHEMBL12062091, CHEBI:91527, KBio2_002262, KBio2_004830, KBio2_007398, KBio3_000804, CCG-38625, SDCCGMLS-0066324.P001, NCGC00095430-01, NCGC00095430-02, BRD-A11483079-001-01-6, 2-isopropyl-2,3-dihydropyrano[2,3-g][1,4]benzodioxin-7-one, 2-propan-2-yl-2,3-dihydropyrano[2,3-g][1,4]benzodioxin-7-one

ID: 1031

InChIKey: JAABVEXCGCXWRR-UHFFFAOYSA-N
SMILES: C1CC2C3C(C1O2)C(=O)OC3=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 93004
synonyms found at PubChem are:
Norcantharidin, 5442-12-6, Endothall anhydride, Norcantharadine, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, 3,6-Endoxohexahydrophthalic anhydride, 29745-04-8, DEMETHYL-CANTHARIDIN, NSC 14003, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, FR-0742, 3,6-Endooxyphthalic anhydride, hexahydro-, Phthalic anhydride, hexahydro-3,6-endoxo-, C8H8O4, 4,10-dioxatricyclo[5.2.1.0<2,6>]decane-3,5-dione, NSC 59023, BRN 0084287, sodium norcantharidate, exo-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3a-alpha,4-beta,7-beta,7a-alpha)-, 3, hexahydro-, Norcantharidin, solid, Spectrum_001667, SpecPlus_000904, AC1L3PAJ, 4,3-dione, hexahydro-, Spectrum2_001683, Spectrum3_001634, Spectrum4_000601, Spectrum5_001514, D0S9QL, D0W4IL, CHEMBL8327, Lopac0_000830, BSPBio_003327, KBioGR_001122, KBioSS_002147, Phthalic anhydride,6-endoxo-, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, exo-, MLS002153470, DivK1c_007000, SCHEMBL177729, SPECTRUM1504153, SPBio_001606, norcantharidin, (3aalpha,4beta,7beta,7aalpha)-isomer, CTK5A0933, KBio1_001944, KBio2_002147, KBio2_004715, KBio2_007283, KBio3_002547, TIMTEC-BB SBB005955, JAABVEXCGCXWRR-UHFFFAOYSA-N, MolPort-001-508-621, HMS3262F21, HMS3370H07, 4,7-Epoxyisobenzofuran-1,3-dione, 51154-98-4, BCP09826, NSC14003, NSC59023, Tox21_500830, WLN: T C555 A AO DVOVTJ, CCG-39454, NSC-14003, NSC-59023, NSC148536, SBB005955, STK424286, Hexahydro-3,6-epoxyphthalic anhydride, AKOS003267901, AKOS022167759, FCH1677597, LP00830, MCULE-7561066553, NSC-148536, NCGC00015756-03, NCGC00015756-04, NCGC00015756-05, NCGC00015756-06, NCGC00015756-07, NCGC00015756-08, NCGC00015756-09, NCGC00094161-01, NCGC00094161-02, NCGC00094161-03, NCGC00094161-04, NCGC00094161-05, NCGC00094161-06, NCGC00261515-01, AN-11544, LS-98753, LS-98754, NCI60_001019, SC-14983, SMR000326693, ST057264, TR-019245, 4,4'-Diamino-2,4'-stilbenedisulfonic acid, EU-0100830, FT-0614776, FT-0621477, N1662, 4,7-Epoxyisobenzofuran-1,3-dione,hexahydro-, hexahydro-4,7-epoxy-2-benzofuran-1,3-dione, N 8784, SR-01000076037, I14-0105, SR-01000076037-1, BRD-A66914119-001-04-0, 4,10-Dioxa-tricyclo[5.2.1.02,6]decane-3,5-dione, EXO-7-OXA-BICYCLO(2.2.1)-HEPTANE-2,3-DICARBOXYLIC ANHYDRIDE

ID: 1032

InChIKey: JADDQZYHOWSFJD-FLNNQWSLSA-N
SMILES: CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 448222
synonyms found at PubChem are:
NECA, 35920-39-9, 5'-N-Ethylcarboxamidoadenosine, Adenosine-5'-(N-ethylcarboxamide), [3H]NECA, N-ethyl-5'-carboxamidoadenosine, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide, MLS000069759, CHEMBL464859, CHEBI:73284, [3H]adenosine-5'-(N-ethylcarboxamide), SMR000058759, N-Ethylcarboxamidoadenosine, 5'-N(Sup 6)-Ethylcarboxamidoadenosine, 5'-N-ETHYLCARBOXAMIDO-ADENOSINE, (2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, NEC, 5'-ethylcarboxamidoadenosine, 5'-Ethylcarboxamido Adenosine, Adenosine, N6-Ethyl-carboxamido, 2ydv, Adenosine analog, 3, 1qy5, Opera_ID_470, AC1L9LQM, D0K8ZZ, D0W1XA, GTPL377, GTPL425, 5'-Ethylcarboxamido-adenosine, MLS002153347, beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-, REGID_for_CID_448222, SCHEMBL16585523, BDBM21220, (2S,3S,4R)-5-(6-Aminopurin-9-yl)-N-ethyl-3,4-dihydroxy-oxolane-2-carboxamide, (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide, Adenosine-5-(N-ethylcarboxamide), JADDQZYHOWSFJD-FLNNQWSLSA-N, MolPort-023-276-191, HMS2234O07, ZINC3995401, MFCD00069195, AKOS024456749, CS-8131, NCGC00025260-02, NCGC00025260-03, NCGC00025260-04, NCGC00025260-05, 5'-(N-Ethylcarboxamido)adenosine, powder, AC-27392, SC-97607, HY-103173, 5 inverted exclamation mark -Ethylcarboxamido Adenosine, 5 inverted exclamation marka-N-ethylcarboxamidoadenosine, 5 inverted exclamation marka-(N-Ethylcarboxamido)adenosine, 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-?-D-ribofuranuronamide, b-D-Ribofuranuronamide,1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-, 5''-N-Ethylcarboxamidoadenosine; D-NECA; NECAMolecular Formula: C12H16N6O4, 100111-00-0, 110282-65-0, 74992-42-0, 84272-21-9

ID: 1033

InChIKey: JALVTHFTYRPDMB-HRRTYWNUSA-N
SMILES: C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 101379
synonyms found at PubChem are:
Demissidine, Dihydrosolanidine, Demissidin, Solanidan-3beta-ol, UNII-VG66W0726Y, (3-beta,5-alpha)-Solanidan-3-ol, Solanidan-3-ol, (3beta,5alpha)-, EINECS 207-478-1, NSC 409074, (22R,25S)-5alpha-Solanidan-3beta-ol, (22S,25S)-5alpha-Solanidan-3beta-ol, 22R,25S-5alpha-Solanidanine-3beta-ol, 5-alpha-Solanidan-3-beta-ol, (22S,25S)-5-alpha-Solanidan-3-beta-ol, 5alpha-Solanidan-3beta-ol, (22R,25S)-, (22S,25S)-5-alpha-Solanidanine-3-beta-ol, (3beta,5alpha)-Solanidan-3-ol, 474-08-8, VG66W0726Y, Solanine D, Solanin D, AC1L2QPP, 5alpha-Solanidan-3beta-ol, SCHEMBL2683829, CHEMBL2165408, 5alpha-Solanidan-3beta-ol (8CI), LMST01150001, ZINC28539649, CCG-208467, Solanidan-3-ol, (3-beta,5-alpha)-, LS-145580, LS-145581, Solanidan-3-ol, (3-beta,5-alpha)- (9CI), SR-05000002229, SR-05000002229-2

ID: 1034

InChIKey: JAPHQRWPEGVNBT-UTUOFQBUSA-N
SMILES: C1CC(=C(N2[C@H]1[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5284585
synonyms found at PubChem are:
loracarbef, Lorabid, Loracarbefum, 76470-66-1, Loracarbef hydrate, UNII-W72I5ZT78Z, Loribid, Lorafem, KT 3777, Loracarbef monohydrate, LY-163892, W72I5ZT78Z, CHEBI:47544, Loracarbefum [INN-Latin], Lorabid (TN), KT-3777, LY163892, LY 163892, 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid, (6R,7S)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Loracarbef [USAN:INN:BAN], 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))-, Anhydrous loracarbef, Loracarbef (INN), Lorbef (TN), 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylate, 7beta-[(2R)-2-ammonio-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylate, (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7S)-7-{[(2R)-2-ammonio-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, D0E9WL, AC1NR4Q4, CHEMBL1013, LORACARBEF, ANHYDROUS, SCHEMBL34153, BIDD:GT0753, DTXSID7023223, CTK2H7568, JAPHQRWPEGVNBT-UTUOFQBUSA-N, HMS3713L04, 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R,7S)-, ZINC1530993, AKOS015895936, API0004680, CCG-220611, DB00447, D08143, I06-1267, BRD-K28935038-001-01-4, (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, (6R,7S)-, loracarbef zwitterion, CHEBI:214480

ID: 1035

InChIKey: JBEJXNWZBGTDKN-OJBGRLICSA-N
SMILES: C1C([C@H]([C@H](C(C1N)OC2[C@H]([C@H](C(C(O2)CN)O)O)N)OC3[C@H]([C@@H]([C@H](O3)CO)O)O)O)NC(=O)C(CCN)O.OS(=O)(=O)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6419880
synonyms found at PubChem are:
Butirosin disulfate salt, Prestwick_59, 51022-98-1, AC1O4WFO, HMS1570A21, 4-amino-N-[(2R,3R)-5-amino-4-[(3S,4R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-[(3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-hydroxycyclohexyl]-2-hydroxybutanamide; sulfuric acid

ID: 1036

InChIKey: JBGJVMVWYWUVOW-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C2=CC=CC=C2C=C1)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 69733
synonyms found at PubChem are:
711-79-5, 1'-Hydroxy-2'-acetonaphthone, 2-Acetyl-1-naphthol, 1-Hydroxy-2-acetylnaphthalene, 2-Acetyl-1-hydroxynaphthalene, Ethanone, 1-(1-hydroxy-2-naphthalenyl)-, 1-(1-hydroxynaphthalen-2-yl)ethanone, 1-Hydroxy-2-acetonaphthone, 1-(1-Hydroxy-2-naphthalenyl)ethanone, 2'-Acetonaphthone, 1'-hydroxy-, 1-Hydroxy-2-naphthyl methyl ketone, 3',4'-Benzo-2'-hydroxyacetophenone, UNII-N3BKY69086, 2-Aceto-1-naphthol, 1-(1-Hydroxy-naphthalen-2-yl)-ethanone, 1-(1-Hydroxy-2-naphthyl)ethanone, NSC 4973, JBGJVMVWYWUVOW-UHFFFAOYSA-N, N3BKY69086, Ethanone,1-(1-hydroxy-2-naphthalenyl)-, 1-(1-hydroxynaphthalen-2-yl)ethan-1-one, NSC4973, EINECS 211-918-8, ACMC-209ohj, AI3-00856, AC1L2CJH, alpha-Hydroxyacetonaphthone, AC1Q1JV9, AC1Q5GK9, 1-Hydroxy-2-acetonaphthalene, SCHEMBL431650, CHEMBL569194, DTXSID4061044, CTK5D3650, MolPort-001-759-193, ZINC154709, KS-00000V0J, NSC-4973, 1-(1-Hydroxy-2-naphthyl) Ethanone, 8552AE, ANW-36005, BBL012750, SBB010063, STK070535, 1'-Hydroxy-2'-acetonaphthone, 99%, 1-(1-Hydroxy-2-naphthyl)ethanone #, AKOS000119758, 1-(1-hydroxy-2-naphthyl)-1-ethanone, MCULE-2060868197, NE10287, VZ20794, 2'-Acetonaphthone, 1'-hydroxy- (8CI), KB-66268, SC-22278, ZB005859, DB-055504, TL8006622, TR-044006, BB 0261365, FT-0607920, ST50331808, 2-(1-Hydroxyethylidene)naphthalene-1(2H)-one, I01-10424, InChI=1/C12H10O2/c1-8(13)10-7-6-9-4-2-3-5-11(9)12(10)14/h2-7,14H,1H

ID: 1037

InChIKey: JBGKVNQFVAJOGC-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C(=C1)C=C3C=CC=C(C3=C2O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10288
synonyms found at PubChem are:
3-Methylanthralin, 3-Methyl-1,8,9-anthracenetriol, Purified araroba, 491-59-8, Chrysophanic acid anthranol, 1,8,9-Anthracenetriol, 3-methyl-, UNII-0433FJV3CI, 1,8,9-Trihydroxy-3-methylanthracene, CCRIS 5597, 1,8-Dihydroxy-3-methylanthron, 3-Methyl-1,8,9-trihydroxyanthracene, BRN 2124735, AI3-62089, 0433FJV3CI, 3-methylanthracene-1,8,9-triol, JBGKVNQFVAJOGC-UHFFFAOYSA-N, 3-Methyl-1,8-dihydroxy-9,10-dihydro-9-oxoanthracen, NCGC00181774-01, DSSTox_CID_28597, DSSTox_RID_82868, DSSTox_GSID_48671, CAS-491-59-8, Purified goa powder, Chrysophansaureanthranol, AC1L1UVW, AC1Q7AY4, 4-06-00-07604 (Beilstein Handbook Reference), SCHEMBL5858623, CHEMBL2135835, DTXSID1048671, CTK4J1116, Tox21_113041, 2C15H12O3, ACM491598, AKOS030530690, Tox21_113041_1, ZINC100090070, NCGC00181774-02, CJ-32387, LS-20394, LS-187737, FT-0632219

ID: 1038

InChIKey: JBJYTZXCZDNOJW-JLHYYAGUSA-N
SMILES: COC1=CC(=C(C(=C1)OC)/C=C/2\C3=CC=CC=C3NC2=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5288600
synonyms found at PubChem are:
ic261, IC 261, 3-[(2,4,6-Trimethoxyphenyl)methylidenyl]-indolin-2-one, SU5607, 186611-52-9, CHEMBL489156, SU-5607, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, 3-(2,4,6-trimethoxybenzylidene)indolin-2-one, (3E)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one, 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one, IC1, AC1NRBRK, Lopac-I-0658, Lopac0_001017, SCHEMBL2786157, MolPort-002-894-454, HMS1433C06, HMS3229I10, HMS3263K15, ZINC136945, Tox21_501017, BDBM50263829, HSCI1_000024, MFCD00118156, s8237, AKOS030632794, CCG-205097, CS-4967, DB03083, LP01017, SU5607 (IC261), IDI1_012141, NCGC00015546-01, NCGC00015546-02, NCGC00015546-03, NCGC00015546-04, NCGC00094309-01, NCGC00094309-02, NCGC00261702-01, HY-12774, EU-0101017, I 0658, SR-01000075566, J-011989, SR-01000075566-1, BRD-K09638361-001-01-4

ID: 1039

InChIKey: JBMKAUGHUNFTOL-UHFFFAOYSA-N
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2720
synonyms found at PubChem are:
chlorothiazide, 58-94-6, Diuril, Chlorthiazide, Chlorothiazid, Chlotride, Chlortiazid, Thiazide, Chlorosal, Chlorurit, Saluretil, Warduzide, Alurene, Clotride, Diuresal, Diurilix, Diurite, Diutrid, Salisan, Salunil, Saluric, Yadalan, Flumen, Minzil, Urinex, Neo-Dema, Chlorothiazidum, Sk-chlorothiazide, Chlorthiazid, Chlorthiazidum, Clorotiazida, Aldoclor, Diupres, Clorotiazide, Chloriazid, Chlrosal, Clorotiazide [DCIT], Diuril Boluses, Diuril Boluses, Veterinary, 6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Clorotiazida [INN-Spanish], Chlorothiazidum [INN-Latin], component of Aldoclor, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide, 6-Chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, C7H6ClN3O4S2, NSC 25693, Diuril (TN), CCRIS 5999, UNII-77W477J15H, Chlorothiazide [USAN:INN:BAN], HSDB 3030, EINECS 200-404-9, MLS000028398, CHEBI:3640, Chlorothiazide (JAN/USP/INN), JBMKAUGHUNFTOL-UHFFFAOYSA-N, NSC25693, 77W477J15H, CAS-58-94-6, NCGC00015242-04, SMR000058429, 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, DSSTox_CID_2800, C 4911, DSSTox_RID_76733, DSSTox_GSID_22800, 6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, SR-01000075604, chlorotiazida, Mechlozid, 6-chloro-1,1-dioxo-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Diuril;Chlotride, Chlorothiazide [USP:INN:BAN], Prestwick_56, Diupres (Salt/Mix), Aldoclor (Salt/Mix), Spectrum_000134, AC1L1EBB, Prestwick0_000251, Prestwick1_000251, Prestwick2_000251, Prestwick3_000251, Spectrum2_000154, Spectrum3_000342, Spectrum4_000280, Spectrum5_001446, Lopac-C-4911, CHEMBL842, D0M9WM, cid_2720, Lopac0_000254, SCHEMBL22329, BSPBio_000062, BSPBio_002003, KBioGR_000780, KBioSS_000594, BIDD:GT0635, DivK1c_000675, SPECTRUM1500180, SPBio_000288, SPBio_002281, BPBio1_000070, GTPL4835, CHEMBL3392493, DTXSID0022800, BDBM39351, Chlorothiazide, thiazide diuretic, CTK8F8613, HMS502B17, KBio1_000675, KBio2_000594, KBio2_003162, KBio2_005730, KBio3_001223, Diuril, Chlotride, Chlorothiazide, MolPort-003-666-143, MolPort-003-845-912, NINDS_000675, HMS1568D04, HMS1920K15, HMS2091C18, HMS2095D04, HMS2232N22, HMS3259K15, HMS3260D10, HMS3370A15, HMS3655M13, HMS3712D04, Pharmakon1600-01500180, BCP24474, HY-B0224, KS-00001F6W, ZINC3872055, Tox21_110107, Tox21_200972, Tox21_500254, WLN: T66 BSWM ENJ HG ISZW, CCG-38953, LS-244, MFCD00058576, NSC-25693, NSC756682, s1641, AKOS015896601, AKOS024319450, Tox21_110107_1, CS-2171, DB00880, LP00254, MCULE-3497410863, NC00500, NSC-756682, IDI1_000675, NCGC00015242-01, NCGC00015242-02, NCGC00015242-03, NCGC00015242-05, NCGC00015242-06, NCGC00015242-07, NCGC00015242-08, NCGC00015242-09, NCGC00015242-10, NCGC00015242-12, NCGC00015242-13, NCGC00091042-01, NCGC00091042-02, NCGC00091042-03, NCGC00091042-04, NCGC00091042-05, NCGC00258525-01, NCGC00260939-01, AC-18732, AN-10251, AS-11760, CPD000058429, SAM002554891, SC-45427, ACM1189440796, SBI-0050242.P004, AB0010688, AB2000186, EU-0100254, FT-0602975, C07461, D00519, AB00051940-04, AB00051940_05, AB00051940_06, 102632-EP2270011A1, 102632-EP2272841A1, 102632-EP2277879A1, 102632-EP2298776A1, 102632-EP2301936A1, I06-2278, SR-01000075604-1, SR-01000075604-3, SR-01000075604-5, W-105353, BRD-K88682005-001-05-9, BRD-K88682005-001-07-5, Z1691545266, 6-Chloro-7-sulfamoyl-2H-1,4-benzothiadiazine 1,1-dioxide, 6-Chloro-2H-1,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Chlorothiazide, European Pharmacopoeia (EP) Reference Standard, 2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-, 1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide, 6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-4H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, Chlorothiazide, United States Pharmacopeia (USP) Reference Standard, Chlorothiazide, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 1040

InChIKey: JBTQLUUOBPYIPP-FMLJXKFRSA-N
SMILES: C[C@]12CC[C@@H](C[C@@H]1CCC3C2CC[C@]4(C3CCC4=O)C)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708555
synonyms found at PubChem are:
Spectrum_000669, 3beta-chloroandrostanone, SpecPlus_000100, Spectrum2_000363, Spectrum3_000120, Spectrum4_001399, Spectrum5_000138, AC1O8FD1, BSPBio_001740, KBioGR_001758, KBioSS_001149, SPECTRUM100586, DivK1c_006196, SPBio_000485, KBio1_001140, KBio2_001149, KBio2_003717, KBio2_006285, KBio3_000880, CCG-39729, NCGC00179042-01, (3S,5S,10S,13S)-3-chloro-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

ID: 1041

InChIKey: JCBIVZZPXRZKTI-UHFFFAOYSA-N
SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 12947
synonyms found at PubChem are:
HYDROXYCHLOROQUINE SULFATE, 747-36-4, Hydroxychloroquine sulphate, Ercoquin, Plaquinol, Toremonil, 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate, Hydroxychloroquine sulfate [USP], TCMDC-123987, EINECS 212-019-3, Plaquenil (TN), AI3-52706, NSC 4375, DSSTox_CID_27788, hydroxychloroquine; sulfuric acid, 2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), AK-72909, DSSTox_RID_82563, Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt), C18H28ClN3O5S, DSSTox_GSID_47811, W-104413, 2-((4-((7-chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol sulfate, (+-)-2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt), 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol; sulfuric acid, CAS-747-36-4, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethyl)amino-, (+-)-, sulfate (1:1) salt, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1), SR-05000001881, NCGC00159483-02, C18H26ClN3O.H2O4S, Plaquenil sulfate, 2-((4-(7-chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol sulfate, 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid, 7-Chloro-4-[4-[ethyl-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline, HCQ sulfate, Ethanol, monosulfate, Oxichlorochine Sulfate, PubChem15393, AC1L20PB, CHEMBL1690, SCHEMBL41114, SPECTRUM1503978, HYDROXYCHLOROQINE SULFATE, 118-42-3 (Parent), DTXSID1047811, Hydroxychloroquine Sulfate ,(S), CTK8B4131, KS-00000GEU, MolPort-003-666-519, Ethanol, sulfate (1:1) (salt), HMS1922O12, HMS2093O05, HMS3713J22, Pharmakon1600-01503978, BCP12823, HY-B1370, NSC-4375, Tox21_111707, ANW-43969, CCG-39154, NSC758663, s4430, Hydroxychloroquine sulfate (JAN/USP), AKOS015897337, Tox21_111707_1, API0025948, CS-8017, KS-5311, MCULE-4122662001, NSC-758663, Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt), NCGC00095090-01, NCGC00095090-02, NCGC00159483-04, AN-22118, BR-72909, CPD000525253, LS-66615, M567, SAM001246735, ACM1216432562, AB0015282, AX8134190, KB-219927, TR-024132, 4CH-007360, FT-0603511, ST24030764, Hydroxycloroquine sulfate, analytical standard, D02114, J10260, S-2011, 747H364, Hydroxychloroquine sulfate, >=98% (HPLC), powder, SR-05000001881-1, SR-05000001881-2, Z1551900864, Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base), 2-((4-((7-Chloroquinolin-4-yl)amino)-pentyl)(ethyl)amino)ethanol sulfate, 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate, 2-[4-[(7-chloro-4-quinolyl)amino]pentyl-ethyl-amino]ethanol; sulfuric acid, 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol; sulfuric acid, 7-Chloro-4-[4-[N-ethyl-N-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline Sulfate, Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material, Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard, N4-(7-Chloro-4-quinolyl)-N1-ethyl-N1-(2-hydroxyethyl)-1,4-pentanediamine Sulfate, Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) (8CI)

ID: 1042

InChIKey: JCCNYMKQOSZNPW-UHFFFAOYSA-N
SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3957
synonyms found at PubChem are:
loratadine, 79794-75-5, Claritin, Loratidine, Alavert, Clarityn, Lisino, Clarityne, Loracert, Loradex, Bonalerg, Claritine, Fristamin, Histaloran, Lertamine, Lorastine, Loratyne, Civeran, Loranox, Versal, Allertidin, Polaratyne, Aerotina, Alerpriv, Anhissen, Biloina, Claratyne, Clarinase, Lesidas, Loradif, Lorantis, Loraver, Lorfast, Loritine, Lowadina, Nularef, Optimin, Restamine, Rhinase, Rinomex, Sanelor, Sensibit, Sohotin, Velodan, Alarin, Lergy, Pylor, Tadine, Zeos, Sinhistan Dy, Bedix Loratadina, Talorat Dy, Claritin Reditabs, Clarinase Reperabs, Loratadina, Loratadinum, Loratadinum [Latin], Claratyne Cold, Claritin reditab, Loratadina [Spanish], Clarityne-D, Sch 29851, Sch-29851, Children's Claritin, Clarium, Claratyne Decongestant, Clarityne Dy Repetabs, Claritin D, Loratadine Redidose, Claritin Hives Relief, Roletra, UNII-7AJO3BO7QN, ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate, Claritin (TN), Claritin Hives Relief Reditab, Loratadine [USAN:BAN:INN], HSDB 3578, 7AJO3BO7QN, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate, CHEMBL998, C22H23ClN2O2, Loratadine (JAN/USAN/INN), MLS000069647, JCCNYMKQOSZNPW-UHFFFAOYSA-N, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-, ethyl ester, 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester, NCGC00015619-09, SMR000058255, DSSTox_CID_3224, L 9664, DSSTox_RID_76931, DSSTox_GSID_23224, 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester, Bactimicina allergy, 1-piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-,ethyl ester, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cycloheptal[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate, ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, CAS-79794-75-5, SR-01000075968, Cronopen, Flonidan, Klaritin, Sch29851, Alavert;Claritin, Topcare childrens allergy relief, Loratadine,(S), Claritine (TN), Clarityne (TN), Fristamin (TN), Loratadine [USAN:USP:INN:BAN], Symphoral (TN), Clarityn (TN), Flonidan (TN), Alavert (TN), AllergyX (TN), Lomilan (TN), Lorfast (TN), Rinolan (TN), Roletra (TN), Tidilor (TN), Loratadine Wyeth Brand, Spectrum_001496, Tocris-1944, Opera_ID_1868, Spectrum2_001584, Spectrum3_000740, Spectrum4_000177, Spectrum5_001650, Lopac-L-9664, Wyeth Brand of Loratadine, D06ABF, AC1L1H3E, SCHEMBL4596, Lopac0_000680, Oprea1_027965, REGID_for_CID_3957, BSPBio_002300, KBioGR_000693, KBioSS_001976, MLS000758260, MLS001148466, MLS001423984, Alavert, Claritin, Loratadine, BIDD:GT0198, DivK1c_000792, SPECTRUM1503712, SPBio_001548, CHEBI:6538, GTPL7216, DTXSID2023224, BDBM22876, CTK8G0633, HMS502H14, KBio1_000792, KBio2_001976, KBio2_004544, KBio2_007112, KBio3_001520, KS-00000JOZ, MolPort-002-507-846, NINDS_000792, HMS2051G11, HMS2090O18, HMS2093I15, HMS2235G23, HMS3262G21, HMS3268M16, HMS3371D13, HMS3393G11, HMS3654L17, HMS3714E09, Pharmakon1600-01503712, ZINC537931, Loratadine 0.1 mg/ml in Methanol, ACT04775, BCP22338, Tox21_110185, Tox21_301532, Tox21_500680, BBL010757, CCG-39362, CL0028, DL-436, FC1275, HTS028367, MFCD00672869, NSC721075, NSC758628, s1358, STK574925, AKOS005499513, Loratadine, >=98% (HPLC), powder, Tox21_110185_1, AB06849, AC-2086, BCP9000858, CCG-100786, CS-0887, DB00455, KS-1079, LP00680, MCULE-5073177964, NC00036, NSC-721075, NSC-758628, IDI1_000792, NCGC00015619-01, NCGC00015619-02, NCGC00015619-03, NCGC00015619-04, NCGC00015619-05, NCGC00015619-06, NCGC00015619-07, NCGC00015619-08, NCGC00015619-10, NCGC00015619-11, NCGC00015619-12, NCGC00015619-13, NCGC00023125-02, NCGC00023125-04, NCGC00023125-05, NCGC00023125-06, NCGC00023125-07, NCGC00255171-01, NCGC00261365-01, AJ-23376, AN-14336, CPD000058255, HY-17043, NCI60_041473, SAM001246987, SC-13436, ZB014352, BCP0726000007, SBI-0050659.P003, AB0012486, AB2000066, LS-114660, ST2413201, TL8005389, EU-0100680, FT-0627976, L0223, D00364, J10034, M-5196, AB00053224-15, AB00053224-16, AB00053224_17, AB00053224_18, 794L755, L000667, I14-0747, Q-100833, SR-01000075968-1, SR-01000075968-3, SR-01000075968-4, SR-01000075968-6, BRD-K82795137-001-02-3, BRD-K82795137-001-10-6, Z1741979837, Loratadine, European Pharmacopoeia (EP) Reference Standard, Loratadine, United States Pharmacopeia (USP) Reference Standard, Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material, Loratadine for system suitability, European Pharmacopoeia (EP) Reference Standard, 1-Piperidenecarboxylic acid, 4-(8-chloro-5,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester, 1-Piperidenecarboxylic acid,6-duhydro-11H-benzo [5,6]cyclohepta[1,2-b]-pyridin-11-ylidene)-, ethyl ester, 11-[N-(ethoxycarbonyl)-4-piperidylidene]-8-chloro-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]pyridine, 4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE, 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acidethyl ester, 4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester, 4-(8-chloro-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester, 8-chloro-11-(1-ethoxycarbonyl-4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1- ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-Chloro-6,11-dihydro-11-(1-ethoxycarbonyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, ETHYL 4-(13-CHLORO-4-AZATRICYCLO[9.4.0.0(3,8)]PENTADECA-1(11),3(8),4,6,12,14-HEXAEN-2-YLIDENE)PIPERIDINE-1-CARBOXYLATE, Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidine)-1-piperidinecarboxylate, ethyl 4-(8-chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0(3),]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}piperidine-1-carboxylate, ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0;{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate, loratadine impurity c;4-(4,8-dichloro-5,6-dihydro-11h-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

ID: 1043

InChIKey: JCDRZCWRRLKLTB-UHFFFAOYSA-N
SMILES: CNCCC1=CC(=C(C=C1)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 86470
synonyms found at PubChem are:
N-Methyldopamine hydrochloride, 62-32-8, Epinine hydrochloride, Ephinine hydrochloride, Methyldopamine hydrochloride, Deoxyepinephrine hydrochloride, UNII-ZV3MG8PAX3, N-Methyldopamine HCl, EINECS 200-528-3, ZV3MG8PAX3, 3,4-Dihydroxyphenylethylmethylamine hydrochloride, 4-(2-Methylaminoethyl)pyrocatechol hydrochloride, NSC 294897, 3,4-Dihydroxyphenyl-1-methylamino-2-ethane hydrochloride, 3,4-Dihydroxyphenethylmethylammonium chloride, deoxyepinephrine, EPININE HCl, 4-(2-(Methylamino)ethyl)benzene-1,2-diol hydrochloride, 4-[2-(methylamino)ethyl]benzene-1,2-diol hydrochloride, Methyl-(beta-(3,4-dihydroxyphenyl)ethyl)amine hydrochloride, Pyrocatechol, 4-(2-(methylamino)ethyl)-, hydrochloride, Pyrocatechol, 4-[2-(methylamino)ethyl]-, hydrochloride, Methyldopamine HCl, SMR000326768, 4-[2-(Methylamino)ethyl]-1,2-benzenediol, AC1L3BMB, AC1Q3F7D, N-Methyldopaminehydrochloride, MLS000859907, MLS001332603, MLS001332604, N-Methyl Dopamine Hydrochlorie, N-methyl dopamine hydrochloride, SCHEMBL1320882, CHEMBL1256484, CTK8C5228, WLN: QR BQ D2M1 &GH, 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-hydrochloride, DTXSID90211027, JCDRZCWRRLKLTB-UHFFFAOYSA-N, MolPort-001-757-325, 1,2-Benzenediol, 4-(2-(methylamino)ethyl)-, hydrochloride, ZX-AT001333, Tox21_500390, ANW-74853, KM0599, MFCD00035074, NSC294897, OR1575, SBB093199, 4-[2-(Methylamino)ethyl]pyrocatechol, AKOS015965249, CCG-221694, LP00390, MTB0000346, NSC-294897, PS-8162, Deoxyepinephrine hydrochloride crystalline, NCGC00093818-01, NCGC00261075-01, AC-20364, KB-58534, AX8145089, DB-001742, LS-136446, TC-163598, EU-0100390, FT-0650241, Methyl[b-(3,4-dihydroxyphenyl) ethyl] amine, 1, 4-[2-(methylamino)ethyl]-, hydrochloride, 3,4-Dihydroxyphenylethylmethyamine hydrochloride, D 5886, N-Methyl-3,4-hydroxyphenethylamine hydrochloride, C-45961, SR-01000075369, Epinine hydrochloride; Deoxyepinephrine hydrochloride, SR-01000075369-1, 4-[2-(methylamino)ethyl]benzene-1,2-diol, chloride, 4-[2-(methylamino)ethyl]-1,2-benzenediol hydrochloride, 4-[2-(Methylamino)ethyl]benzene-1,2-diol hydrochlorid, 4-[2-(methylamino)ethyl]benzene-1,2-diol,hydrochloride, Methyl-[.beta.-(3,4-dihydroxyphenyl)ethyl]amine hydrochloride, 1,2-Benzenediol, 4-(2-(methylamino)ethyl)-, hydrochloride (9CI)

ID: 1044

InChIKey: JCKYGMPEJWAADB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2708
synonyms found at PubChem are:
chlorambucil, 305-03-3, Ambochlorin, Chloroambucil, Leukeran, Chloraminophen, Chlorbutin, Chloraminophene, Chlorobutine, Amboclorin, Chlorbutine, Chlorobutin, Linfolizin, Linfolysin, Ecloril, Elcoril, Phenylbutyric acid nitrogen mustard, Lympholysin, Chlocambucil, Leukersan, Leukoran, Chloorambucol, Chlorbutinum, Elcorin, 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid, Cb l348, Chlorambucilum, Clorambucile, Clorambucilo, Clorambucile [DCIT], CB 1348, Phenylbuttersaeure-lost, Leukeran tablets, NSC 3088, NSC-3088, Rcra waste number U035, NCI-C03485, Chlorambucilum [INN-Latin], Clorambucilo [INN-Spanish], 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid, Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, N,N-Di-2-chloroethyl-gamma-p-aminophenylbutyric acid, Leuk ersan, Chlorambucil [INN:BAN], 4-(p-Bis(beta-chloroethyl)aminophenyl)butyric acid, CCRIS 126, 4-(Bis(2-chloroethyl)amino)benzenebutanoic acid, p-(N,N-Di-2-chloroethyl)aminophenyl butyric acid, UNII-18D0SL7309, CHEBI:28830, Phenylbuttersaeure-lost [German], HSDB 3026, NSC3088, LEUKERAN (TN), EINECS 206-162-0, 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, CHEMBL515, RCRA waste no. U035, gamma-[p-Di(2-chloroethyl)aminophenyl]butyric acid, CB-1348, 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid, Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-, BRN 0999011, AI3-26083, MLS000028443, 4-(Bis(2-chloroethyl)amino)phenylbutyric acid, 4-[Bis(2-chloroethyl)amino]benzenebutyric acid, 4-[Bis(2-chloroethyl)aminophenyl]butyric acid, JCKYGMPEJWAADB-UHFFFAOYSA-N, p-(N,N-Di-2-chlorethylaminophenyl)butyric acid, para-(Di(2-chloroethyl)aminophenyl)butyric acid, gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid, 4-(p-(Bis(2-chloroethyl)amino)phenyl)butyric acid, Butanoic acid, 4-(bis(2-chloroethyl)amino) benzene, gamma-(p-Bis(2-chloroethyl)aminophenyl)butyric acid, gamma-(p-Di(2-chloroethyl)aminophenyl)butyric acid, Butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)-, p-N,N-Di-(beta-chloroethyl)aminophenyl butyric acid, Butyric acid, 4-(p-(bis(2-chloroethyl)amino)phenyl), para-N,N-Di(beta-chloroethyl)aminophenyl butyric acid, 18D0SL7309, Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna, N,N-Di-2-chloroethyl-gamma-para-aminophenyl butyric acid, NCGC00015199-08, CAS-305-03-3, SMR000058372, DSSTox_CID_263, Kyselina 4-(N,N-bis-(2-chlorethyl)-p-aminofenyl)maselna [Czech], 4-[Bis(2-chloroethyl)amino]phenylbutyric acid, chlorambucil,4-bis(2-chloroethyl)amino]benzenebutanoic acid, n,n-di-2-chloroethyl-, DSSTox_RID_75472, DSSTox_GSID_20263, 4-(4-(Bis(2-chloroethyl)amino)phenyl)butanoic acid, W-106940, .gamma.-[p-Di(2-chloroethyl)aminophenyl]butyric acid, 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid, Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]-, p-N,N-Di-(.beta.-chloroethyl)aminophenyl butyric acid, 4-(p-[bis-(2-Chloroethyl)-amino]-phenyl)-butyric acid, N,N-Di-2-chloroethyl-.gamma.-p-aminophenylbutyric acid, SR-01000000062, 4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid, 4-[4-[Bis(2-chloroethyl)amino]phenyl]butyric Acid, .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acid, .gamma.-[p-bis(2-chloroethyl)aminophenyl]butyric acid, 4-(p-Bis(.beta.-chloroethyl)aminophenyl)butyric acid, 4-[p-Bis(.beta.-chloroethyl)aminophenyl]butyric acid, Butyric acid, 4-(p-[bis(2-chloroethyl)amino]phenyl)-, Chlorambucil [USP:INN:BAN], Chlorambucil,(S), phenyl)butanoic acid, CB1348, Opera_ID_51, PubChem21331, Spectrum_000118, AC1L1EAB, Prestwick0_001079, Prestwick1_001079, Prestwick2_001079, Prestwick3_001079, Spectrum2_000065, Spectrum3_000336, Spectrum4_000273, Spectrum5_000677, Chlorambucil (USP/INN), Lopac-C-0253, D0V8QT, Epitope ID:139977, AC1Q75DO, SCHEMBL4308, Lopac0_000227, WLN: QV3R DN2G2G, BSPBio_001098, BSPBio_001971, KBioGR_000766, KBioSS_000558, 4-14-00-01715 (Beilstein Handbook Reference), MLS001076130, DivK1c_000688, SPECTRUM1500171, Chlorambucil (JAN/USP/INN), SPBio_000249, SPBio_002999, Wellcome Brand of Chlorambucil, Phenylbuttersaeure-lost[German], BPBio1_001208, GTPL7143, ZINC1115, DTXSID7020263, CTK8E8346, HMS502C10, KBio1_000688, KBio2_000558, KBio2_003126, KBio2_005694, KBio3_001191, MolPort-000-152-694, NINDS_000688, HMS1571G20, HMS1920M15, HMS2090M19, HMS2091A22, HMS2098G20, HMS2235A04, HMS3259I10, HMS3372O04, HMS3652P08, Pharmakon1600-01500171, 4-(4-(bis(2-chloroethyl)amino), BCP28394, Tox21_110096, Tox21_201390, Tox21_302996, BDBM50003677, CCG-39872, Glaxo Wellcome Brand of Chlorambucil, GlaxoSmithKline Brand of Chlorambucil, GP0879, MFCD00021783, NSC756674, s4288, AKOS024319346, Tox21_110096_1, API0003150, Chlorambucil, purum, >=98.0% (T), CS-3118, DB00291, GS-6200, LP00227, LS-1158, MCULE-2575006904, NC00555, NSC-756674, IDI1_000688, NCGC00015199-01, NCGC00015199-02, NCGC00015199-03, NCGC00015199-04, NCGC00015199-05, NCGC00015199-06, NCGC00015199-07, NCGC00015199-09, NCGC00015199-10, NCGC00015199-11, NCGC00015199-12, NCGC00015199-13, NCGC00015199-14, NCGC00015199-15, NCGC00015199-16, NCGC00015199-17, NCGC00015199-19, NCGC00015199-20, NCGC00023250-00, NCGC00023250-03, NCGC00023250-04, NCGC00023250-05, NCGC00023250-06, NCGC00023250-07, NCGC00023250-08, NCGC00023250-09, NCGC00023250-10, NCGC00256464-01, NCGC00258941-01, AN-16019, BC208809, BP-24028, CC-25645, CPD000058372, HY-13593, KB-48833, NCI60_002639, SAM002564202, SC-16653, SC-54759, SBI-0050215.P004, AB0093202, TL8002353, TR-013105, AB00051938, EU-0100227, FT-0083565, FT-0617365, ST50410766, KS-00001815, A18607, C 0253, C06900, D00266, 4-(p-bis(2-chloroethyl)aminophenyl)butyric acid, AB00051938-14, AB00051938-15, AB00051938_16, 305C033, 4-((p-bis(b-chloroethyl)amino)phenyl)butyric acid, C-18948, 4[p-Bis(.beta.-chloroethyl)aminophenyl]butyric acid, Butanoic acid, 4-(bis(2-chloroethyl)amino)benzene-, SR-01000000062-2, SR-01000000062-4, SR-01000000062-7, .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyricacid, BRD-K29458283-001-04-2, BRD-K29458283-001-05-9, BRD-K29458283-001-17-4, 4-(4-[Bis(2-chloroethyl)amino]phenyl)butanoic acid #, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)buty ric acid, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid, Z1558572529, 4-[4-(N,N-bis(2-chloroethyl)-amino]phenyl)butanoic acid, ETHANAMINE,2-[[4-(1-METHYLETHOXY)PHENYL]SULFONYL]-, N,N-Di-(2-chloroethyl)-gamma-(p-aminophenyl)butyric acid, Chlorambucil, European Pharmacopoeia (EP) Reference Standard, Chlorambucil, United States Pharmacopeia (USP) Reference Standard, Chlorambucil for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 1045

InChIKey: JCSGFHVFHSKIJH-UHFFFAOYSA-N
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 176158
synonyms found at PubChem are:
280744-09-4, SB 216763, 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, SB216763, SB-216763, 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-, CHEMBL102714, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione, SR-01000076052, Tocris-1616, Lopac-S-3442, D0A1YQ, AC1L41YI, Lopac0_000934, SCHEMBL30251, MLS001074894, BDBM8296, cid_176158, GTPL8015, CHEBI:91421, CTK8B4807, AOB5004, DTXSID90182349, EX-A291, SYN1075, JCSGFHVFHSKIJH-UHFFFAOYSA-N, MolPort-003-983-830, BCPP000073, HMS2235H21, HMS3244K13, HMS3244K14, HMS3244L13, HMS3262L10, HMS3268I05, HMS3373J13, HMS3654K15, KS-000008GB, ZINC1493890, Tox21_500934, ABP000231, ANW-46345, BS0214, GL9739, MFCD09753369, RS0041, s1075, AKOS015995247, ACN-029378, AN-5325, CCG-101287, CS-0139, LP00934, PB17645, NCGC00015949-01, NCGC00015949-02, NCGC00015949-03, NCGC00015949-04, NCGC00015949-05, NCGC00025232-01, NCGC00025232-02, NCGC00025232-03, NCGC00261619-01, 4CA-1130, AJ-26350, HY-12012, KB-80493, SC-73083, SMR000568414, AB0023939, AX8157915, LS-186079, RT-015653, B5716, EU-0100934, FT-0688716, ST24028269, W5100, C-8276, F10088, S 3442, SB 216763, >98% (HPLC), SB 216763/SB-216763, 744D094, A819314, J-510466, SR-01000076052-1, SR-01000076052-3, BRD-K59184148-001-04-2, 3-(2,4-DICHLOROPHENYL)-4-(1-METHYL-1H-INDOL-3-YL)-, 3-(2,4-dichlorophenyl)-4-(1-methyl-3-indolyl)pyrrole-2,5-dione, SB216763, SB-216763, 280744-09-4, 3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)-1H-pyrrole-2,5-dione, 3-(2,4-Dichlorophenyl)-4-(1-methyl- 1H-indol-3-yl)-1H-pyrrole-2,5-dione

ID: 1046

InChIKey: JCXKHYLLVKZPKE-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=NN2N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1367
synonyms found at PubChem are:
1-aminobenzotriazole, 1614-12-6, 1H-Benzotriazol-1-amine, 1H-benzo[d][1,2,3]triazol-1-amine, benzotriazol-1-amine, 1-Benzotriazolamine, 1-Abtz, 1H-1,2,3-Benzotriazol-1-amine, 1H-1,2,3-Benzotriazol-1-ylamine, UNII-9EFF75BJ1O, NSC 114498, 9EFF75BJ1O, CHEMBL101168, benzotriazolylamine, MFCD00132902, NSC656987, AK-830/25033013, Q-102063, 1-benzotriazolylamine, benzotriazol-1-ylamine, PubChem19954, ACMC-1BVFA, rarechem aq nn 0550, AC1L1BBK, timtec-bb sbb004208, Lopac-A-3940, ABT; 1-Benzotriazolamine, D07ANY, 1h-benzotriazole,1-amino-, AC1Q4XI6, Lopac0_000056, SCHEMBL94751, MLS001056764, 1,2,3-benzotriazol-1-amine, ASIS-0066, CTK0H6517, BIA0115, DTXSID80167140, JCXKHYLLVKZPKE-UHFFFAOYSA-N, MolPort-001-768-990, ZX-AFC001579, HMS2235A14, HMS3260K13, HMS3374C01, ZINC230381, ZX-AT009876, Tox21_500056, ANW-21933, BDBM50106744, CA-921, FCH931136, NSC114498, OR5609, SBB004208, AKOS001013369, CCG-204151, INB0000279, LP00056, MCULE-8247729764, MS-1148, NSC-114498, NSC-656987, KS-00000M40, 1-Aminobenzotriazole, >=98.0% (GC), NCGC00015056-01, NCGC00015056-02, NCGC00015056-03, NCGC00015056-04, NCGC00093570-01, NCGC00093570-02, NCGC00260741-01, AK113523, AN-49537, KB-11123, LS-41531, NCI60_019729, SMR000326746, AX8056438, HY-103389, RT-001211, 4CH-024521, B7737, CS-0027797, EU-0100056, FT-0691063, ST24038267, ST51037135, A 3940, M-3405, M01240, 614A126, SR-01000075675, I10-0830, SR-01000075675-1, BRD-K19037540-001-07-8, InChI=1/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H

ID: 1047

InChIKey: JDJZONYSWOVTTL-UHFFFAOYSA-N
SMILES: C1=COC(=C1)C2=NOC(=C2)CCO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10631189
synonyms found at PubChem are:
3-(2-Furanyl)-5-isoxazoleethanol

ID: 1048

InChIKey: JDPQWWYZTFVRDQ-UHFFFAOYSA-N
SMILES: C(C1=CC=C([NH0+]([OH0-])=O)S1)1C(C(=O)OCC=C)=C(C)NC(C)=C1C(=O)OCC=C

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazzei" "MT Mazzei" "F Cateni" "M Giampieri" "N Pedemonte" "P Fossa" "LJ Galietta" "M Zacchigna"

CID is 46227462
synonyms found at PubChem are:
CHEMBL604686

ID: 1049

InChIKey: JDTZAGLGBRRCJT-UHFFFAOYSA-N
SMILES: CC#CCOC(=O)C1=C(N=C2C(=C1N)C3=C(S2)CC(CC3)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 197690
synonyms found at PubChem are:
SB 205384, SB-205384, 160296-13-9, 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo(b)thieno(2,3-b)pyridine-3-carboxylic acid but-2-ynyl ester, 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester, SR-01000076138, AC1L53UD, SB 205384, solid, Lopac0_001119, MLS002153326, CHEMBL1256667, SCHEMBL17236317, CHEBI:91586, JDTZAGLGBRRCJT-UHFFFAOYSA-N, MolPort-003-959-599, HMS2232M03, HMS3263O20, HMS3268A07, HMS3370F18, Tox21_501119, BN0457, AKOS024456640, API0007584, CCG-205195, LP01119, NCGC00015969-03, NCGC00015969-04, NCGC00015969-05, NCGC00025197-02, NCGC00162349-01, NCGC00261804-01, SMR001230739, EU-0101119, S 7936, J-009707, SR-01000076138-2, SR-01000076138-3, BRD-A22707317-001-02-5, 4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-[1H]benzothieno[2,3-b]pyridine-3-carboxylic acid 2-butynyl ester, but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylate

ID: 1050

InChIKey: JDUMTSOFUMWLJQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NC2=C(OC3=CC=CC=C32)C(=O)N

biological descriptors:

reference list:

"K Du" "AS Verkman" "H Yang" "T Ma" "N Pedemonte" "GL Lukacs" "VS Gopinath" "AA Shelat" "A Taddei" "C Folli" "LJ Galietta" "RK Guy"

CID is 570268
synonyms found at PubChem are:
3-benzamidobenzofuran-2-carboxamide, 3-benzamido-1-benzofuran-2-carboxamide, 68217-75-4, JDUMTSOFUMWLJQ-UHFFFAOYSA-N, 3-Benzoylamino-benzofuran-2-carboxylic acid amide, AC1LC69T, Cambridge id 6432655, Oprea1_760585, MLS000528875, SCHEMBL3118545, CHEMBL1308755, CTK7F8402, ZINC58361, CHEBI:115706, MolPort-001-964-434, HMS1692O04, HMS2313B21, STK070406, AKOS000507241, MCULE-7381463762, BAS 01508074, SMR000121350, ST079168, Benzofuran-2-carboxamide, 3-benzoylamino-, 2-benzofurancarboxamide, 3-(benzoylamino)-, 3-(Benzoylamino)-1-benzofuran-2-carboxamide, EU-0017189, 3-(Benzoylamino)-1-benzofuran-2-carboxamide #, 3-(phenylcarbonylamino)benzo[b]furan-2-carboxamide, 3-[(phenylcarbonyl)amino]-1-benzofuran-2-carboxamide, F0834-0768, Z108545860, A0111/0004866

ID: 1051

InChIKey: JDVVGAQPNNXQDW-TVNFTVLESA-N
SMILES: C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 54445
synonyms found at PubChem are:
castanospermine, 79831-76-8, Castinospermine, 1,6,7,8-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, 6-Epicastanospermine, UNII-Q0I3184XM7, 6,7-Diepicastanospermine, NSC 625381, CHEBI:27860, Q0I3184XM7, Castanospermine, Castanospermum australe, (1S,6S,7R,8aR)-Tetrahydroxyoctahydroindolizine, (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol, (1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol, (1S-(1alpha,6beta,7alpha,8beta,8alphabeta))-octahydro-1,6,7,8-indolizinetetrol, CTS, SR-01000597675, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol, Indolizine der., NSC625381, 2cbu, Octahydro-indolizine-1,6,7,8-tetraol, CID54445, 1-epicastanospermine, CAST, (+)-Castanospermine, D09NYB, MolMap_000013, UPCMLD-DP122, SCHEMBL61040, BSPBio_001552, KBioGR_000272, KBioSS_000272, MLS000028641, AC1L1H19, AC1Q59T8, CHEMBL311226, UPCMLD-DP122:001, UPCMLD-DP122:002, UPCMLD-DP122:003, BCBcMAP01_000133, BDBM36388, CTK8F8488, KBio2_000272, KBio2_002840, KBio2_005408, KBio3_000543, KBio3_000544, BIC0126, JDVVGAQPNNXQDW-TVNFTVLESA-N, MolPort-003-845-673, ZX-AFC000445, Bio1_000396, Bio1_000885, Bio1_001374, Bio2_000272, Bio2_000752, HMS1361N14, HMS1791N14, HMS1989N14, HMS2232G11, HMS3266B08, HMS3402N14, HY-N2022, ZINC3775177, MDL-26190, MFCD00017555, AKOS024458634, CCG-208170, CS-5633, DB01816, FCH3937985, IDI1_034022, SMP1_000059, NCGC00024773-02, NCGC00024773-04, LS-83622, SC-66601, SMR000059227, B6439, Octahydro-indolizine-1,6,7,8-tetraol, 13, C02256, SR-01000597675-1, SR-01000597675-4, W-203822, (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetraol, 81041B9A-D148-44DC-A86D-C78D6ABF9633, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine, 98%, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine, [1S-(1?,6?,7?,8?,8a?)]-Octahydro-1,6,7,8-indolizinetetrol, Castanospermine, >=94% (GC), BioUltra, from Castanospermum australe seeds, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1-alpha,6-beta,7-alpha,8-beta,8a-beta))-, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1alpha,6beta,7alpha,8beta,8abeta))-, 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1alpha,6beta,7alpha,8beta,8alphabeta))-

ID: 1052

InChIKey: JDZOTSLZMQDFLG-BTJKTKAUSA-N
SMILES: C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5284439
synonyms found at PubChem are:
Perhexiline maleate, 6724-53-4, Perhexiline maleate salt, Pexid, 2-(2,2-Dicyclohexylethyl)piperidine maleate, Perhexiline maleate [USAN], CCRIS 5491, C19H35N.C4H4O4, rac Perhexiline Maleate, EINECS 229-775-5, MLS000028601, MLS001077289, 2-(2,2-Dicyclohexylethyl)piperidine acid maleate, 2-(2,2-Dicyclohexylethyl)piperidine maleate (1:1), 2-(2,2-Dicyclohexylethyl)piperidinium hydrogen maleate, Piperidine, 2-(2,2-dicyclohexylethyl)-, maleate (1:1), NCGC00095025-01, SMR000058713, DSSTox_CID_1114, Piperidine, 2-(2,2-dicyclohexylethyl)-, (Z)-2-butenedioate (1:1), Perhexiline maleate (USAN), DSSTox_RID_75947, DSSTox_GSID_21114, 2-(2,2-dicyclohexylethyl)piperidine (2Z)-but-2-enedioate, SMR000653478, SR-01000000246, 2-(2,2-DICYCLOHEXYLETHYL)PIPERIDINE 2-BUTENEDIOATE, Pexsid, Pexsig, 2-[2,2-DICYCLOHEXYLETHYL]PIPERIDINE MALEATE SALT, Prestwick_636, Opera_ID_1791, PERHEXILLINE MALEATE, CAS-6724-53-4, AC1NR4G7, MLS006010628, SCHEMBL123149, SPECTRUM1503227, CHEMBL1334033, DTXSID1021114, HMS501L04, HY-B1334A, AOB5092, MolPort-003-666-460, REGID_for_CID_5284439, HMS1568J14, HMS1922K11, HMS2092P06, HMS2095J14, HMS2231C20, HMS2231N03, HMS3712J14, Pharmakon1600-01503227, Tox21_111395, CCG-39317, MFCD00057329, NSC758409, AKOS024285312, Tox21_111395_1, CS-7871, NSC-758409, NCGC00018261-06, NCGC00095025-02, NCGC00095025-03, NCGC00095025-04, ST083072, Perhexiline maleate salt, >=98% (HPLC), LS-114986, X4611, VU0239842-5, D05442, (+/-)-2-(2,2-Dicyclohexylethyl)piperidine Maleate, SR-01000000246-2, SR-01000000246-4, (Z)-but-2-enedioic acid; 2-(2,2-dicyclohexylethyl)piperidine, 2-(2,2-dicyclohexylethyl)piperidine, (2Z)but-2-enedioic acid, Piperidine, 2-(2,2-dicyclohexylethyl)-, 2-butenedioate (1:1)

ID: 1053

InChIKey: JEJFTTRHGBKKEI-UHFFFAOYSA-N
SMILES: CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 43595
synonyms found at PubChem are:
Deoxyschisandrin, Deoxyschizandrin, schisandrin A, 61281-38-7, CHEBI:80818, hexamethoxy(dimethyl)[?], R(+) Deoxyschisandrin A, Schizandrin-A, Dimethylgomisin J, AC1L2A7F, CHEMBL479898, SCHEMBL2703836, Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamethoxy-, HMS3327E22, Dibenzo(a,c)cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, stereoisomer, AKOS015897176, CCG-208606, NCGC00163662-01, AN-39355, LS-60866, FT-0624519, Deoxyschizandrin, 98%, from magnoliavine P.E, C16951, W-2898, I07-0289, 5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene

ID: 1054

InChIKey: JEKMKNDURXDJAD-HWUKTEKMSA-N
SMILES: C[C@@]12C=CC3=C([C@H]1CC[C@]45[C@H]2CC[C@H](C4)[C@](C5)(CO)O)C=CO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 114778
synonyms found at PubChem are:
Kahweol, 6894-43-5, CCRIS 1521, 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS,5aS,7R,8R,10aR,10bS)-, 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-, AC1L3FY2, SCHEMBL237066, CHEMBL1494598, SCHEMBL18058616, ZINC6032238, NCGC00163593-01, LS-185961, SR-05000002309, SR-05000002309-2, 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-

ID: 1055

InChIKey: JEMJAABFSYOLAP-UHFFFAOYSA-N
SMILES: CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5368
synonyms found at PubChem are:
t-0156, T0156, CHEMBL540294, methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate, NCGC00016057-01, Tocris-1676, Lopac-T-8067, D0LZ5R, Lopac0_001212, SCHEMBL687326, AC1L1K75, GTPL5275, CHEMBL1190161, CHEBI:93111, CTK6I8577, ZINC3963610, BDBM50130017, HSCI1_000141, CCG-205286, NCGC00016057-02, NCGC00016057-03, NCGC00025257-01, NCGC00025257-02, BRD-K63516691-001-01-6, BRD-K63516691-003-01-2, 1-Oxo-2-(2-methyl-4-pyridinylmethyl)-4-(3,4,5-trimethoxyphenyl)-8-(2-pyrimidinylmethoxy)-1,2-dihydro-2,7-naphthyridine-3-carboxylic acid methyl ester, 2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-[2,7]naphthyridine-3-carboxylic acid methyl ester; hydrochloride, methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate

ID: 1056

InChIKey: JETSDIPTVSZMLI-UHFFFAOYSA-N
SMILES: CC1=CC(=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4119
synonyms found at PubChem are:
methoxyvone, Spectrum_000014, AC1L1HGD, Spectrum2_000056, Spectrum3_001778, Spectrum4_000130, Spectrum5_000894, BSPBio_003275, KBioGR_000520, KBioSS_000354, DivK1c_000643, SPECTRUM1400666, SPBio_000211, SCHEMBL3409370, CHEMBL1591080, CTK6J5442, HMS502A05, KBio1_000643, KBio2_000354, KBio2_002922, KBio2_005490, KBio3_002776, CHEBI:114181, JETSDIPTVSZMLI-UHFFFAOYSA-N, NINDS_000643, CCG-39990, 7-methoxy-5-methyl-2-phenyl-chromone, IDI1_000643, NCGC00095871-01, NCGC00095871-02, NCGC00178171-01, 7-methoxy-5-methyl-2-phenylchromen-4-one, 7-methoxy-5-methyl-2-phenyl-4h-chromen-4-one, BRD-K56057104-001-02-9, BRD-K56057104-001-03-7

ID: 1057

InChIKey: JFACETXYABVHFD-WXPPGMDDSA-N
SMILES: CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)OC)C)C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 159516
synonyms found at PubChem are:
Pristimerin, 1258-84-0, Celastrol-methylether, UNII-28ZK7PR57S, GNF-PF-476, 28ZK7PR57S, CHEBI:8416, 24-Nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, Pristimerine, methyl (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate, (9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26 -trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester, C30H40O4, methyl (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylate, Celastrol methyl ester, Spectrum_001558, SpecPlus_000649, Spectrum2_000546, Spectrum3_001651, Spectrum4_001681, Spectrum5_000322, AC1L4LZ3, SCHEMBL15020, BSPBio_003401, KBioGR_001942, KBioSS_002038, CHEMBL54804, DivK1c_006745, SPECTRUM1504181, SPBio_000591, MEGxp0_000269, DTXSID5044027, ACon0_000836, CTK4B4863, KBio1_001689, KBio2_002038, KBio2_004606, KBio2_007174, KBio3_002621, MolPort-001-740-445, BCP22624, HY-N1937, ZINC4097723, CCG-38723, MFCD01711331, AKOS032960306, API0006380, CS-6257, SDCCGMLS-0066814.P001, NCGC00178090-01, AN-48942, LS-97293, B7488, ST24049037, X1210, C08633, Q-100112, 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oicacid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, (9b,13a,14b,20a)-, D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20alpha)-, D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester, (20alpha)- (9CI)

ID: 1058

InChIKey: JFBIRMIEJBPDTQ-UHFFFAOYSA-N
SMILES: C1=CC=NC(=C1)C2=NN=C(N=N2)C3=CC=CC=N3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 315109
synonyms found at PubChem are:
1671-87-0, 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine, 3,6-Di(2-pyridyl)-1,2,4,5-tetrazine, 3,6-Di-2-pyridinyl-1,2,4,5-tetrazine, 3,6-Bis(2-pyridyl)-1,2,4,5-tetrazine, 3,6-Di-2-pyridyl-1,2,4,5-tetrazine, 3,6-dipyridin-2-yl-1,2,4,5-tetrazine, MLS000038825, SMR000034589, 3,6-Bis(2-pyridinyl)-1,2,4,5-tetrazine, 1,2,4,5-Tetrazine, 3,6-di-2-pyridinyl-, Bptz, NSC238155, ACMC-209dvt, AC1L7QZV, cid_315109, SCHEMBL2852298, 3,6-Di-2-pyridyl-s-tetrazine, CHEMBL1519146, BDBM41205, CTK4D2571, DTXSID30311116, 3,6-Di(2-pyridyl)-s-tetrazine, MolPort-002-546-239, HMS2750C04, ZINC198788, KS-00000NF7, ANW-22263, CL8001, STK792988, AKOS005611188, MCULE-6801268759, NSC-238155, bis(pyridin-2-yl)-1,2,4,5-tetrazine, AJ-17847, AK-86506, AN-49659, AS-18149, KB-70251, ZB009483, DB-026020, ST2404655, TC-111008, 1,2,4,5-Tetrazine,3,6-di-2-pyridinyl-, 3,6-di(2-pyridinyl)-1,2,4,5-tetraazine, CS-0037379, D3640, FT-0614750, W3633, 3,6-Di-2-pyridyl-1,2,4,5-tetrazine, 96%, 671D870, AE-848/01001002, C-57343, J-010344, I14-49632

ID: 1059

InChIKey: JFIOVJDNOJYLKP-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1Cl)O)SC2=CC(=CC(=C2O)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2406
synonyms found at PubChem are:
bithionol, 97-18-7, Actamer, Bithin, 2,2'-Thiobis(4,6-dichlorophenol), Lorothidol, Bitionol, Bithionol sulfide, Bidiphen, Bisoxyphen, Lorothiodol, Bitin, Bithionolate, Neopellis, Nobacter, Vancide BL, Usaf B-22, Bithional, Bithionolum, 2-Hydroxy-3,5-dichlorophenyl sulfide, TKhsd, Bis(2-hydroxy-3,5-dichlorophenyl) sulfide, Bis(3,5-dichloro-2-hydroxyphenyl) sulfide, Caswell No. 852, 2,2'-sulfanediylbis(4,6-dichlorophenol), Bitionol [INN-Spanish], XL 7, Bithionolum [INN-Latin], 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenyl sulfide, Prevenol, 2-Hydroxy-3,5-dichlorophenyl sulphide, CP 3438, D 26, NCI-C60628, UNII-AMT77LS62O, C12H6Cl4O2S, NSC 47129, Phenol, 2,2'-thiobis[4,6-dichloro-, CCRIS 2043, HSDB 6380, EINECS 202-565-0, EPA Pesticide Chemical Code 064201, Phenol, 2,2'-thiobis(4,6-dichloro-, BRN 2003535, AMT77LS62O, 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylsulfide, AI3-50518, MLS000028403, CHEBI:3131, XL-7, 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol, 2,2'-Thiobis[4,6-dichlorophenol], 2,2'-Thio-bis(4,6-dichlorophenol), NCGC00018163-06, SMR000058374, 2,4-dichloro-6-(3,5-dichloro-2-hydroxy-phenyl)sulfanyl-phenol, DSSTox_CID_1342, DSSTox_RID_76096, DSSTox_GSID_21342, Q-200730, Phenol,2'-thiobis[4,6-dichloro-, WLN: QR BG DG FSR BQ CG EG, 2,3',5,5'-tetrachlorodiphenyl sulfide, CAS-97-18-7, 6-(3,5-dichloro-2-hydroxyphenylthio)-2,4-dichlorophenol, Bithionol [INN:BAN:JAN], Bithionol [INN:BAN:JAN:NF], B1T, Bithin (TN), Spectrum_000088, Bithionol (JAN/INN), AC1L1DLT, Spectrum2_000113, Spectrum3_000319, Spectrum4_000257, Spectrum5_000922, D0QQ1J, cid_2406, PHENOL, 2,2'-THIOBIS(4,6-DICHLORO)-, Oprea1_473080, REGID_for_CID_2406, SCHEMBL64385, BSPBio_001918, KBioGR_000694, KBioSS_000508, ARONIS27111, DivK1c_000639, SPBio_000126, ACMC-209s88, CHEMBL290106, GTPL2338, Bithionol, >=98% (HPLC), DTXSID9021342, BDBM36880, CTK8B2783, HMS501P21, JFIOVJDNOJYLKP-UHFFFAOYSA-, KBio1_000639, KBio2_000508, KBio2_003076, KBio2_005644, KBio3_001418, NSC9872, JFIOVJDNOJYLKP-UHFFFAOYSA-N, MolPort-003-702-306, NINDS_000639, KUC106451N, ZINC608213, 2,2-thiobis(4,6-dichlorophenol), KS-000048LK, NSC-9872, NSC47129, Tox21_110832, Tox21_200384, Tox21_302919, 6068AF, A1B988, ANW-40854, MFCD00055727, NSC-47129, s4552, SBB071906, STL257451, 2,2'-Thiobis (4,6-dichlorophenol), 2,2'-Thiobis-(4,6-dichlorophenol), AKOS015856712, Tox21_110832_1, CS-3874, DB04813, KSC-19-055, LS-2022, MCULE-6591279983, RTR-030210, IDI1_000639, QTL1_000014, NCGC00018163-01, NCGC00018163-02, NCGC00018163-03, NCGC00018163-04, NCGC00018163-05, NCGC00018163-07, NCGC00018163-08, NCGC00018163-09, NCGC00018163-10, NCGC00021272-04, NCGC00021272-05, NCGC00021272-06, NCGC00256573-01, NCGC00257938-01, AN-42826, HY-17592, KB-75549, SC-46723, ZB014602, SBI-0051298.P003, TL8006856, TR-030210, FT-0707601, ST45027186, bis (2-hydroxy-3,5-dichlorophenyl)-sulphide, Bithionol, VETRANAL(TM), analytical standard, C07967, D00802, BIS(2-HYDROXY-3,5-DICHLOROPHENYL)SULFIDE, I09-1509, BRD-K39120595-304-03-9, 2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol, 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)thio]phenol, 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)thio]phenol, 2-[3,5-bis(chloranyl)-2-oxidanyl-phenyl]sulfanyl-4,6-bis(chloranyl)phenol, 1394-04-3, InChI=1/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H

ID: 1060

InChIKey: JFRJCQJVFMHZOO-QZHHGCDDSA-N
SMILES: C1=CC(=CC=C1CC(=O)NC2=CC=C(C=C2)CC(=O)NCCN)NC3=NC=NC4=C3N=CN4[C@H]5[C@@H]([C@@H]([C@H](O5)CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 126054
synonyms found at PubChem are:
CHEMBL1512545, 96760-69-9, Adenosine amine congener hydrate, N-(4-(2-((4-(2-((2-Aminoethyl)amino)-2-oxoethyl)phenyl)amino)-2-oxoethyl)phenyl)adenosine, n-(4-{2-[(4-{2-[(2-aminoethyl)amino]-2-oxoethyl}phenyl)amino]-2-oxoethyl}phenyl)adenosine, 6-Adac, AC1L2POH, AC1Q5PIM, MLS002153192, SCHEMBL3486807, Adenosine amine congener hydrate, MolPort-019-997-103, HMS2231C21, ZINC4475057, BDBM50396917, AKOS030573826, NCGC00163296-01, SMR001230680, A825579, Adenosine, N-(4-(2-((4-(2-((2-aminoethyl)amino)-2-oxoethyl)phenyl)amino)-2-oxoethyl)phenyl)-, N-(2-aminoethyl)-2-[4-[[2-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-6-purinyl]amino]phenyl]-1-oxoethyl]amino]phenyl]acetamide, N-(2-aminoethyl)-2-[4-[[2-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]acetyl]amino]phenyl]acetamide, N-(2-azanylethyl)-2-[4-[2-[4-[[9-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]phenyl]ethanoylamino]phenyl]ethanamide, N-[4-[[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]phenyl]amino]carbonyl]methyl]phenyl]adenosine, N6-[4-[[[4-[[[(2-Aminoethyl)amino]carbonyl]methyl]-anilino]carbonyl]methyl]phenyl]adenosine

ID: 1061

InChIKey: JFSHUTJDVKUMTJ-QHPUVITPSA-N
SMILES: C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 73145
synonyms found at PubChem are:
beta-Amyrin, 559-70-6, Amyrin, beta-Amyrenol, Olean-12-en-3beta-ol, UNII-KM8353IPSO, 3beta-hydroxyolean-12-ene, KM8353IPSO, CHEMBL455098, CHEBI:10352, (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol, b-amyrenol, beta.-Amyrenol, beta.-Amyrin, B-Amyrin, B-Amyrin with hplc, EINECS 209-204-6, NSC 527971, AC1L2JCQ, Olean-12-en-3|A-ol, SCHEMBL377754, (3beta)-olean-12-en-3-ol, AC1Q296T, beta-Amyrin, analytical standard, JFSHUTJDVKUMTJ-QHPUVITPSA-N, MolPort-003-925-568, ZX-AFC002758, (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol, ZINC3978270, (3-.beta.)-Olean-12-en-3-ol, BDBM50241955, AKOS032962060, LMPR0106150015, AN-45932, CC-24585, SC-74203, Olean-12-en-3-ol, (3beta)- (9CI), V0161, C08616, 559A706, C-22188, (3S,4aR,5R,6aR,6bR,8S,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol

ID: 1062

InChIKey: JGABMVVOXLQCKZ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3N2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 161091
synonyms found at PubChem are:
2-phenylquinolin-4-ol, 1144-20-3, 2-Phenyl-1H-quinolin-4-one, 2-Phenyl-4-quinolone, 14802-18-7, 2-Phenyl-4-oxohydroquinoline, 4-Hydroxy-2-phenylquinoline, 2-Phenyl-4(1H)-quinolinone, 4(1H)-Quinolinone, 2-phenyl-, 2-Phenyl-4-quinolinol, MLS000084697, MLS000737592, CHEMBL277148, GNF-PF-4337, JGABMVVOXLQCKZ-UHFFFAOYSA-N, SMR000019044, AB-321/11436913, YT-1 Compound, 1-Azaflavone, 2-phenylquinolin-4(1h)-one, NSC28866, 2-phenyl-quinolin-4-ol, Maybridge1_004160, 2-Phenyl-4-oxy-chinoline, 4-Quinolinol, 2-phenyl-, AC1L4OS4, AC1Q6B8D, 2-Phenyl-4-hydroxyquinoline, Oprea1_460285, SCHEMBL367268, cid_161091, BDBM48563, CTK0H4730, CTK8H0086, HMS553F04, JGABMVVOXLQCKZ-UHFFFAOYSA-, 2-Phenyl-4(1H)-quinolinone #, DTXSID80163869, MolPort-002-486-526, MolPort-002-903-890, HMS2357D14, KUC100225N, ZINC8578607, ANW-73205, CCG-15202, NSC-28866, AKOS000283836, AKOS009868209, MCULE-7831289255, ABA-1056487, NCGC00159760-01, AC-20865, AJ-57641, AN-48716, DB-009183, KB-174134, TC-060573, FT-0723846, FT-0750129, T6170, AB00404244-09, 144P203, A803182, SR-01000391113, SR-01000391113-1, I14-43421, 7L4, InChI=1/C15H11NO/c17-15-10-14(11-6-2-1-3-7-11)16-13-9-5-4-8-12(13)15/h1-10H,(H,16,17)

ID: 1063

InChIKey: JGFYQVQAXANWJU-UHFFFAOYSA-M
SMILES: C(C(=O)[O-])F.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6123
synonyms found at PubChem are:
sodium fluoroacetate, Sodium monofluoroacetate, 62-74-8, Furatol, Yasoknock, Compound 1080, Fratol, Tenate, Fluoroacetic acid sodium salt, Natriumfluoracetat, Fluorakil 3, Sodium fluoacetate, Sodium fluoracetate, Caswell No. 770, Ratbane 1080, Sodium fluoacetic acid, Fluoroctan sodny [Czech], Latka 1080 [Czech], RCRA waste number P058, Natriumfluoracetaat [Dutch], Natriumfluoracetat [German], Sodium fluoroacetate [ISO], Fluoroacetic acid, sodium salt, HSDB 743, UNII-166WTM3843, Sodium fluoroacetate de [French], Sodio, fluoracetato di [Italian], Natriumfluoracetaat, Acetic acid, fluoro-, sodium salt, EINECS 200-548-2, Fluoroacetic acid sodium salt [BSI], Monofluoressigsaures natrium [German], NSC 77690, UN2629, Fluoroacetate de sodium [ISO-French], RCRA waste no. P058, EPA Pesticide Chemical Code 075003, Sodio, fluoracetato di, Sodium fluoroacetate de, AI3-08434, CHEBI:38699, Monofluoressigsaures natrium, 166WTM3843, sodium;2-fluoroacetate, Acetic acid, 2-fluoro-, sodium salt (1:1), Fluoroctan sodny, 144-49-0 (Parent), sodium fluoroacetate,fluoro acetic acid sodium salt,gifblaar poison, compd 1080, Fluoroacetate de sodium, Latka 1080, Sodium Fluoro-Acetate, sodium 2-fluoroacetate, Fluoroacetic acid sodium, Spectrum2_000664, Spectrum3_001693, Spectrum4_000925, Spectrum5_001848, DSSTox_CID_4311, DSSTox_RID_77363, DSSTox_GSID_24311, KBioGR_001450, SPECTRUM330009, SCHEMBL226060, SPBio_000727, CHEMBL369611, DTXSID8024311, CTK5B5863, KBio3_002466, JGFYQVQAXANWJU-UHFFFAOYSA-M, MolPort-001-776-560, Tox21_301420, CCG-40063, AKOS025295568, CAS-62-74-8, NCGC00095771-01, NCGC00255312-01, LS-12190, Sodium fluoroacetate [UN2629] [Poison], Sodium fluoroacetate [UN2629] [Poison], TR-021583, Acetic acid, 2-fluoro-,sodium salt (1:1), F0031, FT-0626471, C18588, Fluoroacetic acid sodium salt 10 ng/microL in Water

ID: 1064

InChIKey: JGMOKGBVKVMRFX-HQZYFCCVSA-N
SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@@H]3[C@H]2C=CC4=CC(=O)CC[C@@]34C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9051
synonyms found at PubChem are:
dydrogesterone, Isopregnenone, 152-62-5, Hydrogesterone, Duphaston, Hydrogestrone, Gestatron, Diphaston, Dufaston, Gynorest, 10alpha-Isopregnenone, Duvaron, Prodel, Retrone, Terolut, Dydrogesteronum, Didrogesterone [DCIT], Didrogesterone, Dydrogesterona, Retro-6-dehydroprogesterone, Dydrogesteronum [INN-Latin], Dydrogesterona [INN-Spanish], delta(6)-Retroprogesterone, Dehydrogesterone, 6-Dehydro-retro-progesterone, delta(sup 6)-Retroprogesterone, 9beta,10alpha-Pregna-4,6-diene-3,20-dione, didrogesterona, Retroprogesterone, 6-dehydro-, Duphaston (TN), UNII-90I02KLE8K, 6-Dehydro-9beta,10alpha-progesterone, Gynorest (TN), CCRIS 9069, HSDB 3321, 6-Dehydroretroprogesterone, EINECS 205-806-8, 9-beta,10alpha-Pregna-4,6-diene-3,20-dione, NSC 92336, Dydrogesterone [USAN:INN:BAN:JAN], (9-beta,10-alpha)-Pregna-4,6-diene-3,20-dione, Pregna-4,6-diene-3,20-dione, (9beta,10alpha)-, 6-Dehydro-9 beta-10 alpha-progesterone, MLS002153947, 90I02KLE8K, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one, CHEBI:31527, (9beta,10alpha)-pregna-4,6-diene-3,20-dione, 9-beta,10-alpha-Pregna-4,6-diene-3,20-dione, 6-Dehydro-9.beta.,10.alpha.-progesterone, DSSTox_CID_2974, DSSTox_RID_76812, DSSTox_GSID_22974, 9beta,10alpha-Pregna-4,6-diene-3,20-dione (8CI), CAS-152-62-5, MLS002695106, NSC92336, NCGC00016413-01, 6 Dehydro 9 beta 10 alpha progesterone, Dydrogesterone [USAN:USP:INN:BAN:JAN], DELTA6-Retroprogesterone, Prestwick0_000671, Prestwick1_000671, Prestwick2_000671, Prestwick3_000671, D0F1UL, AC1L1S7M, .DELTA.6-Retroprogesterone, SCHEMBL37703, BSPBio_000761, Solvay Brand of Dydrogesterone, SPBio_002682, BPBio1_000839, GTPL2878, CHEMBL1200853, DTXSID1022974, HY-B0257A, 9.beta.,6-diene-3,20-dione, Dydrogesterone (JP15/USP/INN), Dydrogesterone (JP17/USP/INN), JGMOKGBVKVMRFX-HQZYFCCVSA-N, HMS1570G03, HMS2097G03, HMS2230C10, HMS3714G03, 9-.beta.,6-diene-3,20-dione, BCP12878, ZINC3875998, Tox21_110429, NSC-92336, AKOS015895532, Tox21_110429_1, AN-5183, CCG-220671, CS-2434, DB00378, GS-6735, NCGC00179445-01, NCGC00179445-03, NCGC00179445-04, BC219535, CC-27423, I033, SC-71085, SMR001233286, LS-118418, AB00513884, (9?,10?)-Pregna-4,6-diene-3,20-dione, D01217, Pregna-4,20-dione, (9.beta.,10.alpha.)-, Pregna-4,6-diene-3,20-dione, (9b,10a)-, AB00513884_04, 152D625, C-23776, SR-01000841256, 9.beta.,10.alpha.-Pregna-4,6-diene-3,20-dione, I06-1088, SR-01000841256-2, W-108050, 9-.beta.,10.alpha.-Pregna-4,6-diene-3,20-dione, BRD-K68620903-001-03-1, BRD-K68620903-001-11-4, Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)-, Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)-(9CI), Pregna-4,6-diene-3,20-dione, (9-beta,10-alpha)- (9CI), (1R,2S,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-6,8-dien-5-one, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

ID: 1065

InChIKey: JGUZGNYPMHHYRK-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC(=C(C2=O)O)C3=CC(=C(C=C3)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281691
synonyms found at PubChem are:
Rhamnetin, 90-19-7, 7-Methoxyquercetin, beta-Rhamnocitrin, 7-O-Methylquercetin, 7-Methylquercetin, Quercetin 7-methyl ether, 3,5,3',4'-Tetrahydroxy-7-methoxyflavone, 7-O-Methyl Quercetin, C.I. 75690, 3,3',4',5-Tetrahydroxy-7-methoxyflavone, NSC 19802, .beta.-Rhamnocitrin, CCRIS 3792, UNII-71803L5F4S, NSC19802, EINECS 201-974-1, BRN 0047741, CHEMBL312163, CHEBI:74992, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one, MFCD00016931, NSC-19802, 71803L5F4S, 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, W-100338, FLAVONE, 7-METHOXY-3,3',4',5-TETRAHYDROXY-, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-chromen-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one, AC1NQYWJ, quercetin-7-methylether, Spectrum_001185, 3,5,3',4'-Tetrahydroxy-7-methoxyflaone, SpecPlus_000463, Spectrum2_000642, Spectrum3_001343, Spectrum4_001872, Spectrum5_000464, BSPBio_003125, KBioGR_002367, KBioSS_001665, SPECTRUM310031, 5-18-05-00495 (Beilstein Handbook Reference), DivK1c_006559, Rhamnetin, analytical standard, SCHEMBL555118, SPBio_000643, BDBM23410, CTK8G2947, KBio1_001503, KBio2_001665, KBio2_004233, KBio2_006801, KBio3_002345, DTXSID40237979, JGUZGNYPMHHYRK-UHFFFAOYSA-N, MolPort-003-665-818, ZINC3875620, 6323AF, CCG-38555, LMPK12112624, AKOS027320587, 3,4',5-Tetrahydroxy-7-methoxyflavone, SDCCGMLS-0066624.P001, NCGC00095624-01, NCGC00095624-02, NCGC00095624-03, NCGC00178254-01, AN-42510, LS-69024, NCI60_001648, 3 3' 4' 5-tetrahydroxy-7-methoxyflavone, Flavone,3',4',5-tetrahydroxy-7-methoxy-, LY 805921, FT-0672192, ST50331696, C10176, Flavone, 3,3',4',5-tetrahydroxy-7-methoxy-, C-57547, SR-05000002269, SR-05000002269-2, 3,5,3',4'-Tetrahydroxy-7-methoxyflavone with HPLC, BRD-K37206356-001-01-3, Flavone, 3,3',4',5-tetrahydroxy-7-methoxy- (8CI), 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-y-methoxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy- (9CI)

ID: 1066

InChIKey: JHEWMLHQNRHTQX-UHFFFAOYSA-N
SMILES: CCCCCC1=C2C(=CC(=C1C(=O)O)O)OC(=O)C3=C(O2)C=C(C=C3C(=O)CCCC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 73157
synonyms found at PubChem are:
Lobaric acid, 522-53-2, CHEMBL551842, Lobraric acid, lobutoic Acid, Usnetic acid, Stereocaulic acid, 11H-Dibenzo(b,e)(1,4)dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, Spectrum_000626, AC1Q5UMD, Spectrum2_000310, Spectrum3_001177, Spectrum4_001443, Spectrum5_000025, AC1L2JD8, BSPBio_002793, KBioGR_001925, KBioSS_001106, SPECTRUM300018, cid_73157, MLS001049101, REGID_for_CID_73157, SPBio_000280, SCHEMBL3910434, CHEBI:93548, CTK1H2657, KBio2_001106, KBio2_003674, KBio2_006242, KBio3_002293, DTXSID30200238, JHEWMLHQNRHTQX-UHFFFAOYSA-N, HMS2271L13, NP335, ZINC2139624, ACM522532, BDBM50294526, CCG-38587, AKOS015969735, SDCCGMLS-0066497.P001, NCGC00095570-01, NCGC00095570-02, 8-Hydroxy-3-methoxy-11-oxo-1-pentanoyl-6-pentyl-11H-dibenzo[b,E][1,4]dioxepine-7-carboxylic acid, SMR000386933, SR-01000758235, SR-01000758235-2, BRD-K88849294-001-02-1, BRD-K88849294-001-08-8, 3-hydroxy-9-methoxy-6-oxo-7-pentanoyl-1-pentylbenzo[b][1,4]b, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-6-pentyl-1-valeryl-, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 8-hydroxy-3-methoxy-11-oxo-1-(1-oxopentyl)-6-pentyl-, 3-hydroxy-9-methoxy-6-oxo-7-pentanoyl-1-pentylbenzo[b][1,4]benzodioxepine-2-carboxylic acid, 8-Hydroxy-3-methoxy-11-oxo-1-pentanoyl-6-pentyl-11H-dibenzo[b,E][1,4]dioxepine-7-carboxylic acid #

ID: 1067

InChIKey: JHPHVAVFUYTVCL-UHFFFAOYSA-M
SMILES: CC(C[N+](C)(C)C)OC(=O)C.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6114
synonyms found at PubChem are:
Methacholine chloride, 62-51-1, Acetyl-beta-methylcholine chloride, Provocholine, Mecholyl chloride, Amechol, Methacholine (chloride), Mecholine chloride, 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride, Methacholinium chloride, Acetyl-2-methylcholine Chloride, (2-Acetoxypropyl)trimethylammonium chloride, Metacolina cloruro [DCIT], O-Acetyl-beta-methylcholine chloride, beta-Methylacetylcholine chloride, Cloruro de metacolina [Spanish], Chlorure de methacholine [French], Methacholini chloridum [INN-Latin], EINECS 200-537-2, Cloruro de metacolina [INN-Spanish], DL-Acetyl-beta-methylcholine chloride, Chlorure de methacholine [INN-French], (+-)-Acetyl-beta-methylcholine chloride, AI3-51680, MLS000069656, Trimethyl-beta-acetoxypropylammonium chloride, CHEBI:50142, (2-Hydroxypropyl)trimethylammonium chloride acetate, Mecholyl, Provokit, SMR000059224, 2-acetyloxypropyl(trimethyl)azanium chloride, DSSTox_CID_3271, A-1480, DSSTox_RID_76951, DSSTox_GSID_23271, Q-200715, 2-acetyloxy-N,N,N-trimethylpropan-1-aminium chloride, (+-)-(2-Hydroxypropyl)trimethylammonium chloride acetate, Acetyl- beta-methylcholine chloride, AMMONIUM, (2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, ACETATE, 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1), 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride, (+-)-, Metacolina cloruro, Cloruro de metacolina, Methacholini chloridum, Chlorure de methacholine, SR-01000000215, 2-acetyloxypropyl(trimethyl)azanium;chloride, Acetyl-beta-methacholine Chloride, Methacholine chloride [INN:BAN], Prestwick_981, Provocholine (TN), Methacholine chloride [USP:INN:BAN], CAS-62-51-1, Opera_ID_1285, NCGC00016282-01, AC1L1LU3, 55-92-5 (parent), REGID_for_CID_6114, SCHEMBL69104, C6H11ClNO2.C2H6, MLS001148375, SPECTRUM1500391, 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride, CHEMBL1200764, DTXSID7023271, Acetyl- --methylcholine chloride, CTK8B3014, BIA1090, MolPort-003-666-228, ZX-AFC001554, HMS1570G20, HMS1920L11, HMS2091D06, HMS2097G20, HMS2232B07, HMS3260E11, HMS3371L18, HMS3714G20, Pharmakon1600-01500391, O-Acetyl-|A-methylcholine Chloride, HY-A0083, Tox21_110348, Tox21_500025, 7986AF, ANW-41597, CCG-39988, NSC757090, Acetyl b-methylcholine chloride 98%+, AKOS015892295, Tox21_110348_1, API0024317, LP00025, MCULE-3342474130, Methacholine chloride (JAN/USAN/INN), NSC-757090, NCGC00015045-09, NCGC00093548-01, NCGC00093548-02, NCGC00093548-03, NCGC00093548-04, NCGC00093548-05, NCGC00260710-01, AN-23724, LS-18501, 2-acetoxypropyl(trimethyl)ammonium chloride, TR-021497, 2-acetyloxypropyl(trimethyl)ammonium chloride, AE>> OOo pound(1/4)x>>umicro (1/4)i, EU-0100025, FT-0628268, M0073, ST51039038, A 2251, D04970, AE>> OOo pound-|A-(1/4)x>>umicro (1/4)i, A833819, C-08885, 1-methyl-2-(trimethylamino)ethyl acetate, chloride, 2-acetoxy-N,N,N-trimethylpropan-1-aminium chloride, I02-5955, SR-01000000215-2, SR-01000000215-4, SR-01000000215-7, 2-(acetyloxy)-N,N,N-trimethylpropan-1-aminium chloride, (+/-)-(2-Hydroxypropyl)trimethylammonium chloride acetate, 2410-07-3

ID: 1068

InChIKey: JHRGJMLMFWJXOG-UHFFFAOYSA-N
SMILES: C1C(=O)NN(C1=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 268117
synonyms found at PubChem are:
1-phenylpyrazolidine-3,5-dione, 19933-22-3, 1-Phenyl-3,5-pyrazolidinedione, 1-Phenyl-pyrazolidine-3,5-dione, 3,5-Pyrazolidinedione,1-phenyl-, 3,5-Pyrazolidinedione, 1-phenyl-, AC1L6JKS, AC1Q6EBL, AC1Q6M6W, 1-phenyl-3,5-pyrazolinedione, SCHEMBL3043229, NIOSH/UQ8667200, CTK4E2773, DTXSID60296189, JHRGJMLMFWJXOG-UHFFFAOYSA-N, MolPort-000-893-764, MolPort-039-343-504, NSC108218, STL388177, STL477187, ZINC17885419, 1-phenyl-1,2-diazolidine-3,5-dione, AKOS000312935, MCULE-5848870096, NSC-108218, KB-219741, LS-128716, BB 0238358, ST51010831, UQ86672000, EN300-65929, AE-641/00375061, 2,4-dihydro-2-phenyl-5-hydroxy-3H-pyrazol-3-one, 5-hydroxy-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

ID: 1069

InChIKey: JHTMQDBBUHLBPF-UHFFFAOYSA-N
SMILES: C1CCC(C1)C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N

biological descriptors:

reference list:

"K Du" "AS Verkman" "H Yang" "T Ma" "N Pedemonte" "GL Lukacs" "VS Gopinath" "AA Shelat" "A Taddei" "C Folli" "LJ Galietta" "RK Guy"

CID is 672766
synonyms found at PubChem are:
AC1LDQTT, Oprea1_845061, SCHEMBL3128067, ZINC34601, AKOS003872668, ST050179, EU-0008274, SR-01000463429, SR-01000463429-1, A2796/0118147, 2-(cyclopentanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-(cyclopentylcarbonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide

ID: 1070

InChIKey: JHYXBPPMXZIHKG-UHFFFAOYSA-N
SMILES: C1C(C(=O)C2=C(O1)C=C(C=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JC Fulton" "M Mazur" "PA Sloane" "SM Rowe" "JP Clancy" "J Prasain" "S Barnes" "K Backer" "LC Pyle"

CID is 176907
synonyms found at PubChem are:
dihydrodaidzein, 17238-05-0, 7-hydroxy-3-(4-hydroxyphenyl)chroman-4-one, Dihydrodaidzein (keto), Dihydrodazein, (+/-)-Dihydrodaidzein, Dihydro Daidzein, 7,4'-Dihydroxyisoflavanone, 4',7-Dihydroxyisoflavanone, JHYXBPPMXZIHKG-UHFFFAOYSA-N, 2,3-dihydro-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, Isoflavanone, 4',7-dihydroxy-, AC1L42FE, 4',7-dihydroxy-Isoflavanone, (R,S)-2,3-Dihydrodaidzein, SCHEMBL131543, SCHEMBL16152440, CHEBI:75842, CTK8C3008, BID0517, MolPort-003-846-731, ZX-AFC001619, HY-N1461, ANW-69504, IN2311, LMPK12050447, AKOS016006054, ACM17238050, AK-61048, KB-82949, AX8208356, LS-193361, TC-158249, 7-Hydroxy-3-(4-hydroxyphenyl)-4-chromanone, CS-0016908, D4239, FT-0666948, J-010813, 7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

ID: 1071

InChIKey: JIBZSGQTCBWUKL-RGMNGODLSA-N
SMILES: CC(=NCCC[C@@H](C(=O)O)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 177903
synonyms found at PubChem are:
150403-88-6, L-N5-(1-Iminoethyl)ornithine hydrochloride, N5-(1-Iminoethyl) L-Ornithine Hydrochloride, N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO), L-Ornithine, N5-(1-iminoethyl)-, monohydrochloride, (S)-5-Acetimidamido-2-aminopentanoic acid hydrochloride, L-NIO hydrochloride, 36889-13-1, EU-0100683, AC1L431A, SCHEMBL1320518, CHEMBL1256394, CTK8E7008, DTXSID40164539, AKOS025294561, L-Ornithine |x-acetamidine hydrochloride, N|A-(Iminoethyl)-L-ornithine Hydrochloride, RT-014044, FT-0670311, L-N5-(1-Iminoethyl) ornithine,hydrochloride, I 8768, N(5)-(1-Iminoethyl)-L-ornithine hydrochloride, SR-01000075505, J-008698, SR-01000075505-1, L-N5-(1-Iminoethyl)ornithine hydrochloride, >=95% (HPLC), (2S)-2-amino-5-(1-aminoethylideneamino)pentanoic acid hydrochloride

ID: 1072

InChIKey: JIVPVXMEBJLZRO-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2732
synonyms found at PubChem are:
chlorthalidone, Chlortalidone, 77-36-1, Phthalamudine, Chlorphthalidolone, Hygroton, Chlorthalidon, Phthalamodine, Chlorothalidone, Chlorphthalidone, Natriuran, Saluretin, Thalitone, Zambesil, Igroton, Isoren, Oradil, Renon, Hydro-Long, Oxodolin, Chlortalidonum, Clortalidone, Higroton, Famolin, Urolin, Oksodolin (oxodolin), Racemic chlorthalidone, Clortalidona, Oxodoline, (+-)-Hygroton, Clortalidone [DCIT], (+-)-Chlorthalidone, 2-Chloro-5-(1-hydroxy-3-oxoisoindolin-1-yl)benzenesulfonamide, Chlortalidonum [INN-Latin], Clortalidona [INN-Spanish], G-33182, Tenoretic, G 33182, 1-Keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline, 2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide, 3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine, Thalitone (TN), C14H11ClN2O4S, Hygroton (TN), 3-(4'-Chloro-3'-sulfamoylphenyl)-3-hydroxyphthalimidine, 1-Oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline, Chlorthalidone (USP), Chlorthalidone [USAN:INN:BAN], HSDB 3035, EINECS 201-022-5, NSC 69200, Chlortalidone (JAN/INN), Benzenesulfonamide, 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)-, BRN 0312295, Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-, MLS000069531, CHEBI:3654, JIVPVXMEBJLZRO-UHFFFAOYSA-N, 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide, NSC-69200, SMR000058635, 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide, DSSTox_CID_2812, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide, DSSTox_RID_76738, DSSTox_GSID_22812, W-104322, 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide, SR-01000721929, Chlorthalidone [USAN:USP], Oksodolin, CAS-77-36-1, NCGC00016317-01, Prestwick_759, Chlortalidone [INN], Regroton (Salt/Mix), Combipres (Salt/Mix), Spectrum_000146, Opera_ID_138, AC1L1ECB, (.+/-.)-Hygroton, Prestwick0_000351, Prestwick1_000351, Prestwick2_000351, Prestwick3_000351, Spectrum2_000099, Spectrum3_000349, Spectrum4_000957, Spectrum5_000743, D09NIA, (.+/-.)-Chlorthalidone, CHEMBL1055, SCHEMBL26234, BSPBio_000441, BSPBio_002017, KBioGR_001574, KBioSS_000626, 5-22-07-00602 (Beilstein Handbook Reference), Chlorthalidone (Chlortalidone), DivK1c_000731, SPECTRUM1500187, SPBio_000058, SPBio_002362, AC1Q558X, BPBio1_000487, GTPL7147, DTXSID4022812, BDBM25900, CTK8F8619, HMS502E13, KBio1_000731, KBio2_000626, KBio2_003194, KBio2_005762, KBio3_001237, KS-00000FWZ, MolPort-002-736-049, NINDS_000731, HMS1569G03, HMS1920M09, HMS2091E12, HMS2096G03, HMS2236D07, HMS3259H04, HMS3372A07, HMS3713G03, Pharmakon1600-01500187, BCP27835, NSC69200, Tox21_110369, CCG-38917, NSC756692, STK686335, Chlortalidone 1.0 mg/ml in Methanol, AKOS005599810, Tox21_110369_1, API0001976, CS-2290, DB00310, KS-1342, MCULE-6661021422, NC00690, NSC-756692, VZ31574, IDI1_000731, NCGC00094616-01, NCGC00094616-02, NCGC00094616-03, NCGC00094616-04, NCGC00094616-07, AC-11367, AN-23909, CC-25734, CPD000058635, H530, HY-15833, LS-31408, SAM002589983, ST088141, SBI-0051313.P003, AB0007445, AX8121003, KB-229744, ST2409846, 4CH-007156, AB00051946, FT-0602965, D00272, AB00051946_12, 036C257, C-20285, I06-0208, SR-01000721929-2, SR-01000721929-3, BRD-A26384407-001-05-3, BRD-A26384407-001-15-2, 2-chloro-5-(1-hydroxy-3-oxoisoindolinyl)benzenesulfonamide, A3836/0162845, 2-Chloro-5(1-hydroxy-3-oxo-1-isoindolinyl) benzenesulfonamide, 2-Chloro-5-(1-hydroxy-3-oxo-1H-isoindolinyl)benzenesulfonamide, Chlorthalidone, European Pharmacopoeia (EP) Reference Standard, 2-chloro-5-(1,3-dihydroxy-1H-isoindol-1-yl)benzene-1-sulfonamide, 2-chloro-5-(1-hydroxy-3-oxo-isoindolin-1-yl)benzenesulfonamide, Benzenesulfonamide,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-, Chlorthalidone, United States Pharmacopeia (USP) Reference Standard, 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide #, Chlortalidone for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 1073

InChIKey: JIVSXRLRGOICGA-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5887
synonyms found at PubChem are:
PROMAZINE HYDROCHLORIDE, 53-60-1, Promazine Hcl, Starazin, Talofen, Promazine (hydrochloride), Promazine monohydrochloride, UNII-U16EOR79U4, RP 4560, Chlorowodorek promazyny [Polish], EINECS 200-179-7, NSC 17468, N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine hydrochloride, Promazine hydrochloride [USP], AI3-28022, MLS000069671, U16EOR79U4, N-(3-(Dimethylamino)propyl)phenothiazine hydrochloride, 10-(3-(Dimethylamino)propyl)phenothiazine hydrochloride, 10-(3-(Dimethylamino)propyl)phenothiazine monohydrochloride, 10-(gamma-Dimethylamino-n-propyl)phenothiazine hydrochloride, Phenothiazine, 10-(3-(dimethylamino)propyl)-, hydrochloride, SMR000058499, Sparine (TN), DSSTox_CID_26949, DSSTox_RID_82026, DSSTox_GSID_46949, Promazine hydrochloride (USP), 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride, Phenothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride, 10-H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1), CHEBI:8460, Chlorowodorek promazyny, CAS-53-60-1, SR-01000000228, NCGC00015829-02, N-[3-(Dimethylamino)propyl]phenothiazine hydrochloride, 10-(3-[Dimethylamino]propyl)phenothiazine hydrochloride, 10-[3-(Dimethylamino)propyl]phenothiazine hydrochloride, Esparinal, Verofen, Promazine hydrochloride [USAN], SR-01000000228-4, Promazine chloride, Prestwick_974, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride, Opera_ID_41, AC1L1LCL, Propazin (pharmaceutical), REGID_for_CID_5887, MLS001148436, MLS002222285, SCHEMBL123418, SPECTRUM1500509, CHEMBL1200469, DTXSID4046949, CTK8G2591, BBC/790, MolPort-003-666-271, HMS1570K07, HMS1920L14, Pharmakon1600-01500509, HY-B1225, KS-000018AN, NSC17468, Tox21_110235, Tox21_500961, CCG-40284, MFCD00058535, NSC-17468, NSC757300, AKOS015964305, Tox21_110235_1, API0003941, CS-4873, KS-1384, LP00961, NSC-757300, NCGC00015829-12, NCGC00094262-01, NCGC00094262-02, NCGC00094262-03, NCGC00094262-04, NCGC00094262-05, NCGC00261646-01, AC-18101, AN-41648, U457, AX8149146, KB-258428, LS-105498, EU-0100961, FT-0674047, ST24031269, WLN: T C666 BN ISJ B3N1&1 &GH, D00797, P 6656, SR-01000000228-2, SR-01000000228-8, W-105721, 10-(3-Dimethylaminopropyl)phenothiazine hydrochloride, Z2784093694, Promazine hydrochloride, VETRANAL(TM), analytical standard, 10-(.gamma.-Dimethylamino-n-propyl)phenothiazine hydrochloride, dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine hydrochloride, N,N-dimethyl-3-phenothiazin-10-yl-propan-1-amine hydrochloride, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine hydrochloride, Promazine Hydrochloride 1.0 mg/ml in Methanol (as free base), N,N-Dimethyl-3-(10H-phenothiazin-10-yl)propan-1-aminehydrochloride, N,N-Dimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine hydrochloride, Promazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Promazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 10-(3- paragraph signthorn(1/4)x>>u degrees +/-+/-u>>u).Oaca masculine NIEaNI, AC1LCWAL, AKOS026749940, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-,monohydrochloride, N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine; hydron; chloride, 10-(3-dimethylaminopropyl)phenothiazinium chloride

ID: 1074

InChIKey: JJCQSGDBDPYCEO-XVZSLQNASA-N
SMILES: C1C[C@H]([C@H](O[C@@H]1CN)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 470999
synonyms found at PubChem are:
dibekacin, Panamicin, Dideoxykanamycin B, 34493-98-6, 3',4'-Dideoxykanamycin B, Debecacin, Orbicin, UNII-45ZFO9E525, Dibekacin sulfate, BRN 1441606, Dibekacina, Dibekacine, Dibekacinum, Kappati, CHEBI:37945, 45ZFO9E525, Dibekacine [INN-French], Dibekacinum [INN-Latin], Dibekacina [INN-Spanish], DKB, DKM, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-6))-2-deoxy-L-streptamine, EINECS 252-064-6, (1R,2S,3S,4R,6S)-4,6-diamino-3-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-(1-4)-2-deoxy-, Dibekacin [INN:BAN], Dibekacin (INN), Spectrum_001398, AC1LAM6L, Spectrum2_001528, Spectrum3_000960, Spectrum4_001074, Spectrum5_001613, NCGC00095276-01, DSSTox_CID_2915, AC1Q4UA9, DSSTox_RID_76787, DSSTox_GSID_22915, SCHEMBL49816, KBioGR_001428, KBioSS_001878, SPBio_001316, CHEMBL560976, DTXSID2022915, KBio2_001878, KBio2_004446, KBio2_007014, KBio3_002060, JJCQSGDBDPYCEO-XVZSLQNASA-N, HY-B1129, ZINC8214383, Tox21_111496, AC-315, AKOS025402025, CCG-213771, CS-4725, BC226561, CAS-34493-98-6, D07811, AB01563356_01, (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol, 84D

ID: 1075

InChIKey: JJCWKVUUIFLXNZ-UHFFFAOYSA-M
SMILES: C[N+](C)(C)CCO.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 74724
synonyms found at PubChem are:
Choline Bromide, 1927-06-6, Choline, bromide, UNII-CXC75P7WK9, (2-hydroxyethyl)trimethylazanium bromide, CXC75P7WK9, (2-Hydroxyethyl)trimethylammonium bromide, 2-hydroxyethyl(trimethyl)azanium bromide, NCGC00015219-03, AC1L2MIV, AC1Q1RJZ, ACMC-1BVV7, AC1O4X4J, Choline-methyl-13C bromide, DSSTox_CID_28938, DSSTox_RID_83204, DSSTox_GSID_49012, SCHEMBL192988, CHEMBL1256479, DTXSID6049012, CTK4E1061, JJCWKVUUIFLXNZ-UHFFFAOYSA-M, HMS3260D21, EINECS 217-660-2, Tox21_113514, Tox21_500180, ANW-13562, NSC293906, AKOS015833071, CCG-221484, LP00180, NSC-293906, NCGC00093659-01, NCGC00260865-01, Trimethyl(2-hydroxyethyl)ammonium bromide, CAS-1927-06-6, TR-032210, EU-0100180, C 1754, J-012465, N-(2-hydroxyethyl)-N,N,N-trimethylammonium bromide, SR-01000075745-1, F8881-3843, Ethanaminium,2-hydroxy-N,N,N-trimethyl-, bromide (1:1)

ID: 1076

InChIKey: JJSVXWKQLGHFES-QGZYWIHFSA-N
SMILES: CC1C(C(C(C(O1)O[C@H]2CC[C@@]3(C4[C@@H](C[C@@]5([C@H](CC[C@@]5(C4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)OC(=O)C)C=O)O)OC)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708535
synonyms found at PubChem are:
SARMENTOSIDE B, Spectrum_000633, SpecPlus_000060, Spectrum2_000355, Spectrum3_000109, Spectrum4_001391, Spectrum5_000122, AC1O8FC6, BSPBio_001698, KBioGR_001742, KBioSS_001113, SPECTRUM100568, DivK1c_006156, SPBio_000449, CHEMBL3039304, KBio1_001100, KBio2_001113, KBio2_003681, KBio2_006249, KBio3_000818, CCG-38630, SDCCGMLS-0066300.P001, NCGC00179076-01, [(3S,5S,10S,11R,13R,14S,17R)-3-(5-acetyloxy-3-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-10-formyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl] acetate

ID: 1077

InChIKey: JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES: C(CN)CNCCSP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2141
synonyms found at PubChem are:
amifostine, 20537-88-6, Ethiofos, Gammaphos, Ethyol, Sapep, Apaetp, Aminopropylaminoethyl thiophosphate, WR 2721, 2-(3-Aminopropylamino)ethyl thiophosphate, Amifostina, NSC-296961, AU-95722, YM-08310, UNII-ILA426L95O, Amifostine Ethiofos, NSC296961, Amifostinum, C5H15N2O3PS, Amifostine [USAN:INN:BAN], WR-2721, NSC 296961, S-(2-(3-Aminopropylamino)ethyl) phosphorothioate, BRN 2088122, CHEBI:2636, ILA426L95O, JKOQGQFVAUAYPM-UHFFFAOYSA-N, 2-(3-aminopropylamino)ethylsulfanylphosphonic acid, WR 2721C, S,2-(3-Aminopropylamino)ethyl-phosphorothioic acid, S-2-(3-Aminopropylamino)ethyl phosphorothioic acid, NCGC00015073-02, S-omega-(3-Aminopropylamino)ethyl dihydrogen phosphorothioate, S-(2-((3-Aminopropyl)amino)ethyl) dihydrogen phosphorothioate, Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique [French], DSSTox_CID_2585, Ethiofos Anhydrous, DSSTox_RID_76644, DSSTox_GSID_22585, S-2-(3-aminopropylamino)-ethylphosphorothioic acid, S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen thiophosphate, Phosphorothioic acid, S-(2-(3-aminopropylamino)ethyl) ester, Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate, CAS-20537-88-6, S-[2-(3-Aminopropylamino)ethyl] phosphorothioate, SR-01000075680, YM 08310, S-[2-[(3-Aminopropyl)amino]ethyl] dihydrogen phosphorothioate, CCRIS 9316, HSDB 7560, Amifostine,(S), Spectrum_000332, SpecPlus_000647, Spectrum5_001920, Lopac-A-5922, D06CIE, NCIMech_000622, S 8744, AC1L1D0F, CHEMBL1006, Lopac0_000029, SCHEMBL18464, KBioSS_000812, MLS000028473, BIDD:GT0059, DivK1c_006743, DTXSID8022585, CTK8F7705, KBio1_001687, KBio2_000812, KBio2_003380, KBio2_005948, Acide ((amino-3 propylamino)-2 ethyl)-S-phosphorothioique, 63717-27-1 (monohydrate), MolPort-003-666-801, HMS2090I03, HMS3260E19, HMS3713C06, Pharmakon1600-01503081, 2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester, BCP08957, HY-B0639, KS-00001F8B, Phosphorothioic acid, S-[2-[(3-aminopropyl)amino]ethyl] ester, WR-2721C, Tox21_110077, Tox21_500029, CCG-35734, Ethanethiol, 2-[(3-aminopropyl)amino]-, 1-(dihydrogen phosphate), NSC758236, ZINC21992285, AKOS015895196, Tox21_110077_1, AC-1126, API0001443, CS-2875, DB01143, LP00029, NSC-758236, RL02548, WR-1064, SMP2_000335, 59178-37-9 (di-hydrochloride salt), NCGC00015073-01, NCGC00015073-03, NCGC00015073-04, NCGC00015073-05, NCGC00093549-01, NCGC00093549-02, NCGC00260714-01, AN-15218, AS-13020, BC215613, Ethanethiol, dihydrogen phosphate (ester), NCI60_002485, SC-18798, SMR000058413, Ethanethiol, dihydrogen phosphate- (ester), SBI-0050018.P003, AB0012846, LS-108362, EU-0100029, FT-0622272, 37A886, A 5922, C06819, [2-(3-aminopropylamino)ethylthio]phosphonic acid, 33870-EP2275420A1, 33870-EP2295055A2, 33870-EP2295416A2, 33870-EP2295426A1, 33870-EP2295427A1, 33870-EP2298748A2, 33870-EP2298764A1, 33870-EP2298765A1, 33870-EP2305642A2, 33870-EP2311453A1, 33870-EP2311808A1, 33870-EP2311829A1, AB00053311-04, AB00053311-05, AB00053311_06, A814662, {S-[2-(3-Aminopropylamino)ethyl]} phosphorothioate, 2-(3-azanylpropylamino)ethylsulfanylphosphonic acid, I06-0333, J-013390, J-519582, SR-01000075680-1, SR-01000075680-3, SR-01000075680-5, 2-(3-Aminopropyl)aminoethyl phosphorothioate; WR2721, BRD-K73947551-001-01-0, ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid, 2-(3-aminopropylamino)ethylsulfanylphosphonic acid,trihydrate, Phosphorothioic acid, S-[2-[(3-aminopropyl)amino]ethyl]ester, S-2-(3-aminopropylamino)ethyl O,O-dihydrogen phosphorothioate, {S-[2-[(3-Aminopropyl)amino]ethyl]} dihydrogen phosphorothioate, 2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester (9CI), Ethanethiol, {S-[(3-aminopropyl)amino]-,} dihydrogen phosphate- (ester), 53028-04-9

ID: 1078

InChIKey: JLIDBLDQVAYHNE-LXGGSRJLSA-N
SMILES: CC1=CC(=O)CC(C1(/C=C/C(=C\C(=O)O)/C)O)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5375199
synonyms found at PubChem are:
ABSCISIC ACID, 14375-45-2, (+/-)-Abscisic acid, Abscisinsaeure, Abszisinsaeure, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid, acido abscisico, acide abscissique, (+)-Abscisic acid, 2-cis-abscisic acid, (RS)-Abscisic acid, Dormin, CHEBI:22152, JLIDBLDQVAYHNE-LXGGSRJLSA-N, 2-cis,4-trans-Abscisic acid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-enyl)-3-methylpenta-2,4-d ienoic acid, abscisic acids, PBI-57, (+/-)-Aba, ABA, (+/-)-(cis,Trans)-abscisic acid, ( inverted exclamation markA)-Abscisic acid, Abscisic acid, (+/-)-(2Z,4E)-, Abscisic acid (ABA), AC1NT9EJ, Abscisic acid (+/-)-cis,trans-form [MI], Spectrum5_000342, (+)-Abscisic acid 99%, DSSTox_CID_10604, DSSTox_RID_78851, DSSTox_GSID_30604, BSPBio_002916, SPECTRUM1502234, CHEMBL379808, Jsp004339, DTXSID1030604, CHEBI:62431, MolPort-003-665-998, HMS1921N10, Pharmakon1600-01502234, (+)-2-cis,4-trans-abscisic acid, (2Z,4E)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentadienoic acid, 5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXO-2-CYCLOHEXEN-1-YL]-3-METHYL-2Z,4E-PENTADIENOIC ACID, Tox21_201137, CA-722, CCG-38879, MFCD00066545, NSC759648, SBB003072, AKOS015903032, AN-1423, NSC-759648, SDCCGMLS-0066860.P001, NCGC00017240-02, NCGC00017240-03, NCGC00017240-04, NCGC00017240-05, NCGC00017240-06, NCGC00017240-07, NCGC00091094-01, NCGC00091094-02, NCGC00091094-03, NCGC00091094-04, NCGC00258689-01, 2,4-pentadienoic acid, 5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-, (2Z,4E)-, 4CN-2982, L903, SC-16385, ST056307, CAS-14375-45-2, KB-206885, LS-190476, LS-190722, LS-194449, 4CH-024069, A0792, FT-0082739, 2-cis,4-trans-Abscisic acid, synthetic, 98%, 375A452, J-007868, 13F617B4-6D52-4DAF-ADA1-A7FE2B84E828, (+/-)-Abscisic acid, BioReagent, plant cell culture tested, >=98.5% (HPLC), (2Z,4E)-3-Methyl-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexenyl)-2,4-pentadienoic acid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-cyclohex-2-en-1-yl)-3-methyl-penta-2,4-dienoic acid, (2Z,4E)-5-(1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoicacid, (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-enyl)-3-methylpenta-2,4-dienoic acid, (4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid

ID: 1079

InChIKey: JLKIGFTWXXRPMT-UHFFFAOYSA-N
SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5329
synonyms found at PubChem are:
sulfamethoxazole, 723-46-6, Gantanol, Sulphamethoxazole, Sulfisomezole, Sulfamethoxazol, Metoxal, Sulfamethylisoxazole, Simsinomin, Radonil, Sinomin, Sulphamethoxazol, 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, Sulpha-methoxizole, Sulfamethalazole, Azo-gantanol, Sulphamethylisoxazole, Urobak, Sulfamethoxizole, 3-Sulfanilamido-5-methylisoxazole, Gantanol-DS, 4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide, Bactrimel, Gamazole, Sulfametoxazol, Sulphisomezole, Solfametossazolo, Sulfamethoxazolum, 5-Methyl-3-sulfanilamidoisoxazole, Ro 4-2130, MS 53, 3-Sulphanilamido-5-methylisoxazole, 5-Methyl-3-sulphanil-amidoisoxazole, 3-(p-Aminophenylsulfonamido)-5-methylisoxazole, Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, 5-Methyl-3-sulfanylamidoisoxazole, Azo gantanol, N'-(5-Methyl-3-isoxazolyl)sulfanilamide, N1-(5-Methyl-3-isoxazolyl)sulfanilamide, N'-(5-Methylisoxazol-3-yl)sulphanilamide, 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide, Solfametossazolo [DCIT], 3-(para-Aminophenylsulphonamido)-5-methylisoxazole, Sulfametoxazol [INN-Spanish], Sulfamethoxazolum [INN-Latin], Septran, Trib, Sulphamethalazole, A047, Sulfamethoxazole sodium, UNII-JE42381TNV, Apo-Sulfamethoxazole, CCRIS 567, N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide, CHEBI:9332, N'-(5-Methyl-3-isoxazole)sulfanilamide, HSDB 3186, Ro 6-2580/11, Sulfamethoxazole [USAN:INN:JAN], Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-, Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-, Sulphamethoxazole BP 98, EINECS 211-963-3, SMX, CHEMBL443, NSC 147832, BRN 0226453, 4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide, MLS000069732, JE42381TNV, 4-AMINO-N-(5-METHYL-3-ISOXAZOYL)BENZENESULFONAMIDE, 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide, C10H11N3O3S, N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide, 5-Methyl-3-sulfonylamidoisoxazole, JLKIGFTWXXRPMT-UHFFFAOYSA-N, N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide, Sulfanilamide, N(1)-(5-methyl-3-isoxazolyl)-, ALBB-002089, NSC147832, NCGC00016533-05, NCGC00186654-01, CAS-723-46-6, N1-(5-Methylisoxazol-3-yl)sulfanilamide, SMR000058223, DSSTox_CID_6064, 3-(p-Aminobenzenesulfonamido)-5-methylisoxazole, DSSTox_RID_78001, DSSTox_GSID_26064, 4-Amino-N-[5-methyl-3-isoxazolyl]benzenesulfonamide, [(4-aminophenyl)sulfonyl](5-methylisoxazol-3-yl)amine, 4-Amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide, N1-(5-methylisoxazol-3-yl)-4-aminobenzene-1-sulfonamide, 129378-89-8, SR-01000000217, Gantanol DS, Sulphameth oxazole, DRG-0031, Prestwick_453, Septrin (TN), Septran (Salt/Mix), Septrin (Salt/Mix), Sulfamethoxazole,(S), Eusaprim (Salt/Mix), Spectrum_000994, Sulfamethoxazole(USAN), Opera_ID_882, Maybridge1_007190, Prestwick0_000177, Prestwick1_000177, Prestwick2_000177, Prestwick3_000177, Spectrum2_000788, Spectrum3_000584, Spectrum4_000345, Spectrum5_000982, Sulfamethoxazole [USAN:USP:INN:BAN:JAN], D0AE2X, D0R9OH, Epitope ID:114999, Co-trimoxazole (Salt/Mix), AC1Q2J5R, SCHEMBL3656, Oprea1_114486, Oprea1_285680, BSPBio_000073, BSPBio_002028, KBioGR_000749, KBioSS_001474, KSC635S5T, MLS001055354, MLS001074165, MLS006011871, BIDD:GT0731, DivK1c_000649, SPECTRUM1500550, SPBio_000896, SPBio_001994, AC1L1K42, ARONIS018156, BPBio1_000081, DTXSID8026064, component of Bactrim (Salt/Mix), CTK5D5959, HMS502A11, HMS561O18, JLKIGFTWXXRPMT-UHFFFAOYSA-, KBio1_000649, KBio2_001474, KBio2_004042, KBio2_006610, KBio3_001528, KS-00004AEJ, ZINC89763, EBD3403, WLN: T5NOJ C1 EMSWR DZ, MolPort-000-145-787, NINDS_000649, HMS1568D15, HMS1921A21, HMS2092K03, HMS2095D15, HMS2233L13, HMS3259E06, HMS3372M22, HMS3655O22, HMS3712D15, Pharmakon1600-01500550, BCP02881, HY-B0322, KS-000000QU, Sulfamethoxazole (JP15/USP/INN), Sulfamethoxazole (JP17/USP/INN), Sulfamethoxazole, analytical standard, Tox21_110480, Tox21_200353, ANW-43073, BBL004554, BDBM50029770, CCG-40166, HTS001394, KM1475, MFCD00010546, NSC757328, Ro-42130, s1915, SBB057675, SBB071655, STK007988, AKOS000200952, component of Azo Gantanol (Salt/Mix), Tox21_110480_1, BS-3542, CS-2363, DB01015, LS-1620, MCULE-1450176600, NC00537, NSC-147832, NSC-757328, Ro-4-2130, RTR-023663, TRA0076970, IDI1_000649, NCGC00016533-01, NCGC00016533-02, NCGC00016533-03, NCGC00016533-04, NCGC00016533-06, NCGC00016533-07, NCGC00016533-08, NCGC00016533-09, NCGC00016533-10, NCGC00016533-11, NCGC00016533-12, NCGC00016533-14, NCGC00021995-03, NCGC00021995-04, NCGC00021995-05, NCGC00257907-01, AC-11118, AN-22110, BAS 00836086, CPD000058223, H463, KB-97587, SAM002554930, SC-15160, ST024740, BCP0726000283, N'-(5-Methyl-3-isoxazolyl)-Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-Sulfanilamide, N1-(5-Methyl-3-isoxazolyl)sulphanilamide, SBI-0051524.P003, AB1009297, ST2418109, TL8005058, AB00052099, BB 0242379, FT-0602616, N(1)-(5-Methyl-3-isoxazolyl)sulphanilamide, N^1-(5-Methyl-3-isoxazolyl)-Sulfanilamide, S0361, ST51006798, C07315, D00447, J10090, 4-[N-(5-Methylisoxazol-3-yl)sulphamoyl]aniline, AB00052099-14, AB00052099-16, AB00052099_17, AB00052099_18, Ndimethyl1-(5-methyl-3-isoxazolyl)-Sulfanilamide, I01-0154, Q-201762, SR-01000000217-2, SR-01000000217-3, Sulfamethoxazole, VETRANAL(TM), analytical standard, Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI), Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-(8CI), 4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide, BRD-K28494619-001-05-0, BRD-K28494619-001-15-9, BRD-K28494619-001-26-6, Z57198677, 4-Amino-N-(5-methyl-isoxazol-3-yl)-benzene sulfonamide, 4-AMINO-N-[5-METHYL-3-ISOXAZOLYL]BENZENESULFONAMID, Sulfamethoxazole, certified reference material, TraceCERT(R), SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE), Sulfamethoxazole, European Pharmacopoeia (EP) Reference Standard, Sulfamethoxazole, United States Pharmacopeia (USP) Reference Standard, SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE); TMP/SMX (MIXTURE)), Sulfamethoxazole, Pharmaceutical Secondary Standard; Certified Reference Material, 08D, 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; N1-(5-Methylisoxazol-3-yl)sulfanilamide, InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

ID: 1080

InChIKey: JLPYLHLUHJOPNL-UHFFFAOYSA-N
SMILES: CC1=C(N(C2=C1C=C(C=C2)F)CC3=CC=C(C=C3)Cl)CC(C)(C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 122070
synonyms found at PubChem are:
L-655,240, 103253-15-2, L-655240, CHEMBL362223, JLPYLHLUHJOPNL-UHFFFAOYSA-N, 1-((4-chlorophenyl)methyl)-5-fluoro-a,a-3-trimethyl-(1h)-indole-2-propanoic acid, 3-[1-(4-Chlorobenzyl)-5-fluoro-3-methyl-indol-2-yl]-2,2-dimethyl propanoic acid, SR-01000075967, L 655240, Tocris-1698, Lopac-L-9539, D0I9JH, AC1L3TX4, Lopac0_000670, SCHEMBL3252820, CHEBI:93563, CTK8E8278, MolPort-003-958-591, HMS3268O17, ZINC2526554, BDBM50168772, AKOS024456751, CCG-204756, 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid, NCGC00015618-01, NCGC00015618-02, NCGC00025263-01, KB-146245, RT-013481, B6834, EU-0100670, L 9539, L000335, J-000915, SR-01000075967-1, SR-01000075967-3, BRD-K89402695-001-01-5, 1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoic acid, 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-5-fluoro-alpha,alpha,3-trimethyl-, 3-[1-(4-Chloro-benzyl)-5-fluoro-3-methyl-1H-indol-2-yl]-2,2-dimethyl-propionic acid, 3-[1-(4-chlorobenzyl)-3-methyl-5-fluoroindol-2-yl]-2,2-dimethyl propanoic acid, 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methylindol-2-yl]-2,2-dimethylpropanoic acid, L-655,240|1-[(4-Chlorophenyl)methyl]-5-fluoro-?,?,3-trimethyl-1H-indole-2-propanoic acid

ID: 1081

InChIKey: JLQNXWHJIQWBMH-UHFFFAOYSA-N
SMILES: C1=CC=[N+]2C(=C1)C=C(C3=C2C(=CC=C3)Cl)O.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 9795307
synonyms found at PubChem are:
CHEMBL175225, SCHEMBL2081163, SCHEMBL2081165, 10-chloro-6-hydroxybenzo [c]quinolizinium chloride

ID: 1082

InChIKey: JLRGJRBPOGGCBT-UHFFFAOYSA-N
SMILES: CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5505
synonyms found at PubChem are:
tolbutamide, 64-77-7, Orinase, Artosin, Tolbutamid, Aglicid, Arkozal, Diabetol, Dolipol, Rastinon, Tolumid, Diaben, Orabet, 1-Butyl-3-tosylurea, Willbutamide, Butamide, Diabetamid, Diabuton, Diasulfon, Dirastan, Glyconon, Ipoglicone, Pramidex, Tolbusal, Artozin, Butamid, Drabet, Mobenol, Oralin, Orezan, Orinaz, Oterben, Toluina, Toluvan, Tolylsulfonylbutylurea, Sk-tolbutamide, 1-Butyl-3-(p-tolylsulfonyl)urea, Tolbutamida, Tolbutamidum, N-n-Butyl-N'-tosylurea, N-Butyl-N'-(p-tolylsulfonyl)urea, 1-Butyl-3-(p-methylphenylsulfonyl)urea, 1-p-Toluenesulfonyl-3-butylurea, Beglucin, Butamidum, Diabesan, Tarasina, Tolbutone, Arcosal, Tolbet, 3-(p-Tolyl-4-sulfonyl)-1-butylurea, N-Butyl-N'-p-toluenesulfonylurea, N-(Butylcarbamoyl)-4-methylbenzenesulfonamide, N-(4-Methylphenylsulfonyl)-N'-butylurea, N-Butyl-N'-(4-methylphenylsulfonyl)urea, Orinase (TN), N-(4-Methylbenzenesulfonyl)-N'-butylurea, HLS 831, Apo-Tolbutamide, N-(p-Tolylsulfonyl)-N'-butylcarbamide, N-(Sulfonyl-p-methylbenzene)-N'-N-butylurea, Tolbutamidum [INN-Latin], Benzenesulfonamide, N-[(butylamino)carbonyl]-4-methyl-, Tolbutamida [INN-Spanish], NCI-C01763, N-4-Methylbenzolsulfonyl-N-butylurea, toluran, D 860, Urea, 1-butyl-3-(p-tolylsulfonyl)-, Oramide, Restinon, Tolumide, Novo-Butamide, 3-butyl-1-(4-methylbenzenesulfonyl)urea, N-Butyl-N'-toluene-p-sulfonylurea, UNII-982XCM1FOI, Tol-Tab, CCRIS 592, Tolbutamide [INN:BAN:JAN], N-4-(Methylbenzolsulfonyl)-n-butylurea, 1-Butyl-3-(4-methylphenylsulfonyl)urea, N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide, TOLBUTAMIDE USP, C12H18N2O3S, HSDB 3393, EINECS 200-594-3, NSC 23813, U 2043, 3-[p-Tolyl-4-sulfonyl]-1-butylurea, CHEMBL782, 1-butyl-3-(4-methylphenyl)sulfonylurea, BRN 1984428, 982XCM1FOI, N-(p-Methylbenzenesulfonyl)-N'-butylurea, Benzenesulfonamide, N-((butylamino)carbonyl)-4-methyl-, N-(Sulfonyl-p-methylbenzene)-N'-butylurea, MLS000028399, CHEBI:27999, 3-(p-tolylsulfonyl)-1-butylurea, JLRGJRBPOGGCBT-UHFFFAOYSA-N, N-((Butylamino)carbonyl)-4-methylbenzenesulfonamide, N-(p-tolylsulfonyl)-N'-n-butylurea, 1-Butyl-3-(para-tolylsulfonyl) urea, CAS-64-77-7, NCGC00015999-10, SMR000058363, 3-butyl-1-[(4-methylbenzene)sulfonyl]urea, DSSTox_CID_1359, T 0891, 1-BUTYL-3-(4-METHYLBENZENESULFONYL)UREA, DSSTox_RID_76106, DSSTox_GSID_21359, Diaval, Tolbutamid R.A.N., SR-01000003059, (butylamino)-N-[(4-methylphenyl)sulfonyl]carboxamide, Tolbutamide [USP:INN:BAN:JAN], Prestwick_471, PubChem18102, Spectrum_000447, Opera_ID_112, Tolbutamide Pfizer Brand, AC1L1KHP, Prestwick0_000190, Prestwick1_000190, Prestwick2_000190, Prestwick3_000190, Spectrum2_001210, Spectrum3_000599, Spectrum4_000358, Spectrum5_001272, Tolbutamide Aventis Brand, Tolbutamide Hoechst Brand, Lopac-T-0891, Tolbutamide Butamide Brand, N-n-Butyl-N''-tosylurea, D06OIV, WLN: 4MVMSWR D1, AC1Q2X3T, Apotex Brand of Tolbutamide, Pfizer Brand of Tolbutamide, Tolbutamide, 98% 10g, Aventis Brand of Tolbutamide, Hoechst Brand of Tolbutamide, NCIOpen2_009592, BIDD:PXR0179, CBiol_001920, Lopac0_001154, SCHEMBL15918, BSPBio_000119, BSPBio_001507, BSPBio_002078, KBioGR_000227, KBioGR_000795, KBioGR_002275, KBioSS_000227, KBioSS_000927, KBioSS_002276, 4-11-00-00396 (Beilstein Handbook Reference), Butamide Brand of Tolbutamide, MLS001148399, MLS002152944, Toluina|||Tolumid|||Orinase, DivK1c_000341, SPECTRUM1500581, R.A.N. Brand of Tolbutamide, SPBio_001000, SPBio_002040, BPBio1_000131, GTPL6848, Valdecasas Brand of Tolbutamide, Yamanouchi Brand of Tolbutamide, Tolbutamide (JP15/USP/INN), Tolbutamide (JP17/USP/INN), Tolbutamide, analytical standard, DTXSID8021359, HMS501B03, KBio1_000341, KBio2_000227, KBio2_000927, KBio2_002275, KBio2_002795, KBio2_003495, KBio2_004843, KBio2_005363, KBio2_006063, KBio2_007411, KBio3_000453, KBio3_000454, KBio3_001578, KBio3_002755, KS-00000XIN, BerlinChemie Brand of Tolbutamide, cMAP_000008, MolPort-001-783-540, NINDS_000341, Bio1_000206, Bio1_000695, Bio1_001184, Bio2_000227, Bio2_000707, HMS1361L09, HMS1568F21, HMS1791L09, HMS1989L09, HMS2089C17, HMS2092M21, HMS2095F21, HMS2232H16, HMS3259A08, HMS3263H09, HMS3402L09, HMS3651N03, HMS3712F21, Pharmakon1600-01500581, Berlin-Chemie Brand of Tolbutamide, BCP09192, HY-B0401, NSC23813, ZINC1530703, N-Butyl-N''-(p-tolylsulfonyl)urea, Tox21_110279, Tox21_201612, Tox21_302795, Tox21_501154, BDBM50027886, CCG-39141, LS-278, MFCD00027169, NSC-23813, NSC757354, s2443, SBB058188, 1-Butyl-3-(para-tolylsulfonyl)-urea, AKOS015894999, Tox21_110279_1, 1-(p-toluenesulfonyl)-3-n-butyl-urea, CS-2500, DB01124, LP01154, MCULE-9720356859, NC00543, NE30724, NSC-757354, Tolbutamide 1.0 mg/ml in Acetonitrile, IDI1_000341, IDI1_033977, N-(n-Butyl)-N'-p-toluene-sulfonylurea, NCGC00015999-01, NCGC00015999-02, NCGC00015999-03, NCGC00015999-04, NCGC00015999-05, NCGC00015999-06, NCGC00015999-07, NCGC00015999-08, NCGC00015999-09, NCGC00015999-11, NCGC00015999-12, NCGC00015999-13, NCGC00015999-14, NCGC00015999-15, NCGC00015999-16, NCGC00015999-17, NCGC00015999-19, NCGC00022721-03, NCGC00022721-04, NCGC00022721-05, NCGC00022721-06, NCGC00022721-07, NCGC00022721-08, NCGC00022721-09, NCGC00022721-10, NCGC00256548-01, NCGC00259161-01, NCGC00261839-01, AC-12490, AJ-26683, AN-16594, AS-14136, CPD000058363, K045, KB-81177, SAM002554936, SC-17768, N-(4-Methylphenylsulfonyl)-N''-butylurea, N-Butyl-N''-(4-methylphenylsulfonyl)urea, SBI-0051121.P003, AB1004876, TL8000121, AB00052110, EU-0101154, FT-0603265, ST24031344, ST50409552, BIM-0051121.0001, C07148, D00380, J10018, U-2043, AB00052110-16, AB00052110_17, AB00052110_18, Tolbutamide, VETRANAL(TM), analytical standard, I05-3340, N-((butylamino) carbonyl)-4-methylbenzenesulfonamide, SR-01000003059-2, SR-01000003059-4, SR-01000003059-7, W-104820, BRD-K85119730-001-06-5, BRD-K85119730-001-17-2, Z44591715, Tolbutamide, European Pharmacopoeia (EP) Reference Standard, 1-(([(Butylamino)carbonyl]amino)sulfonyl)-4-methylbenzene #, Tolbutamide, United States Pharmacopeia (USP) Reference Standard, 100735-34-0

ID: 1083

InChIKey: JLTNCZQNGBLBGO-MOPGFXCFSA-N
SMILES: CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)[C@@H]4[C@H](O3)COC5=CC(=C(C=C45)OC)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 442826
synonyms found at PubChem are:
alpha-Toxicarol, TOXICAROL, 82-09-7, CHEBI:9643, AC1L9DGQ, CHEMBL508992, SCHEMBL4742046, ZINC1684799, LMPK12060027, AKOS032949012, 4CN-2964, C10537

ID: 1084

InChIKey: JLVFQWFTNVMTEG-UHFFFAOYSA-N
SMILES: CN1CCCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16114
synonyms found at PubChem are:
Homochlorcyclizine, dihydrochloride, SA 97 dihydrochloride, SA-97, NSC 169498, Homochlorcyclizine, hydrochloride (VAN), 1-(p-Chloro-alpha-phenylbenzyl)hexahydro-4-methyl-1H-1,4-diazepine, dihydrochloride, 1-H,4-Diazepine, 1-(p-chloro-alpha-phenylbenzyl)hexahydro-4-methyl-, dihydrochloride, 1H-1,4-Diazepine, 1-(p-chloro-alpha-phenylbenzyl)hexahydro-4-methyl-, dihydrochloride, AC1L27AE, LS-60173, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane-1,4-diium dichloride, Homochlorcyclizine dihydrochloride, 1982-36-1, 1-[P-CHLORODIPHENYLMETHYL]-4-METHYL-1,4-DIAZACYCLOHEPTANE DIHYDROCHLORIDE, Homoclomin (TN), Prestwick_593, AC1LCV91, SCHEMBL1977999, CHEBI:31671, HMS1568J08, AKOS025392035, ACM1982361, API0013627, CCG-220283, Homochlorcyclizine hydrochloride (JP17), FT-0765025, D01460, C-46188, SR-01000000252, SR-01000000252-2, 1-((4-Chlorophenyl)(phenyl)methyl)-4-methyl-1,4-diazepane dihydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane dihydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane;dihydrochloride

ID: 1085

InChIKey: JLYXXMFPNIAWKQ-UHFFFAOYSA-N
SMILES: C1(C(C(C(C(C1Cl)Cl)Cl)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 727
synonyms found at PubChem are:
lindane, beta-HCH, gamma-HCH, gamma-BHC, Hexachlorane, alpha-HCH, Kwell, 1,2,3,4,5,6-Hexachlorocyclohexane, Benzene hexachloride, Hexicide, gamma-hexachlorocyclohexane, beta-BHC, beta-Lindane, Aalindan, Jacutin, Gamene, Gexane, 58-89-9, epsilon-HCH, BETA-HEXACHLOROCYCLOHEXANE, Agrocide, Aparasin, Aphtiria, Chloresene, Codechine, delta-BHC, delta-HCH, Entomoxan, Gammalin, Gammaterr, Hexachloran, Hexaverm, Hexyclan, Kokotine, Lindafor, Lindosep, Lorexane, Nicochloran, Ovadziak, Owadziak, Pedraczak, Pflanzol, Quellada, Streunex, Aficide, Aplidal, Arbitex, Celanex, Devoran, Gamacid, Hortex, Lendine, Lentox, Lidenal, Lindex, Lintox, Linvur, Mszycol, Omnitox, Scabene, Bexol, Nexit, Viton, alpha-Lindane, Hcch, Hexachlorocyclohexane, Agrocide WP, Agrocide III, Ben-Hex, Ameisentod, Benhexol, Gammexane, Heclotox, Lasochron, Lindatox, Gammalin 20, Neo-scabicidol, gamma-Lindane, Nexit-stark, Bentox 10, Milbol 49, Nexen fb, alpha-BHC, Nexol-E, ALPHA-HEXACHLOROCYCLOHEXANE, DOL GRANULE, Gamacarbatox, Lindagrain, Lindagranox, Lindapoudre, Spruehpflanzol, Agronexit, Esoderm, Gallogama, Gamaphex, Geobilan, Hexatox, Hilbeech, Lindagam, Novigam, Silvanol, Gamiso, Inexit, Isotox, Lindan, 319-84-6, 319-85-7, 319-86-8, gamma-col, Spritz-rapidin, Forst-nexen, Sang gamma, Mglawik L, Agrocide 7, Hungaria L7, Ameisenmittel merck, TRI-6, Spritzlindane, Benzanex, DELTA-HEXACHLOROCYCLOHEXANE, Gamacide, Hexablanc, Hexachlor, Hexapoudre, Hexcidum, Beta-1,2,3,4,5,6-hexachlorocyclohexane, Dolmix, Gamtox, Hexamul, Isatox, Submar, Gyben, delta-Lindane, Geolin G 3, Verindal ultra, beta-Hexachloran, TAP 85, Detox 25, 608-73-1, Arcotal S, Trives-T, alpha-Hexachlorane, gamma BHC, Agrocide 6G, Hexachlorcyclohexan, Lacco HI lin, Drilltox-Spezial Aglukon, beta-Benzene hexachloride, Gamacide 20, gamma Benzene hexachloride, gamma-Benzene hexachloride, hecoltox, Hexachlorocyclohexanes, Ameisenatod, Benhexachlor, Gammahexane, alpha-1,2,3,4,5,6-Hexachlorocyclohexane, Aphtitria, Exagama, Gammahexa, Gammallin, Gammaxene, Gammopaz, Lindalo, Lindamul, Lindano, Lindanum, Lindaterra, Novigan, Benzex, beta-Hexachlorobenzene, Forlin, Gammex, Detmol-extrakt, Fenoform forte, gamma-Hexachlorobenzene, nexen-fb, Detmol Extract, Borer Spray, alpha-Hexachloran, alpha-Benzenehexachloride, delta-Benzenehexachloride, .delta.-Lindane, Agrocide 2, ENT 9,234, PMS Lindane, Kwell-R, alpha-Benzene hexachloride, delta-Benzene hexachloride, BHC (insecticide), HCH [BSI], HCH [ISO], .delta.-BHC, Gamma-mean 400, Agrisol G-20, .delta.-Hexachlorocyclohexane, BHC or HCH, t-HCH, Caswell No. 079, Caswell No. 527, gamma-1,2,3,4,5,6-Hexachlorocyclohexane, gamma-Benzohexachloride, ENT 7,796, ENT 9,232, (+)-alpha-HCH, Latka 666, Gammasan, gamma hexachlor, Lindanum [INN-Latin], am eisenatod, beta-isomer, gamma-Benzenehexachloride, gamma-Hexachlorzyklohexan, Hexit, Atlas steward, BHC, HCH, hilbeec h, Latka 666 [Czech], Lindano [INN-Spanish], Benzene hexachloride-alpha-isomer, Sang-gamma, gamma-HCH or gamma-BHC, Lindam ul, New kotol, Eso derm, nexi t-stark, UNII-59NEE7PCAB, UNII-YM80ODM9PD, Rcra waste number U129, gamma-Hexachlorcyclohexanum, Hexachlorocyclohexane, gamma-isomer, Isot ox, Technical HCH, .alpha.-Lindane, C6H6Cl6, gamma-Hexachlorane, zeta-HCH, 6108-10-7, Hexachlorocyclohexane, beta-, Hexachlorcyclohexan [German], ENT 8,601, ENT 9,233, .alpha.-Hexachlorocyclohexane, Hexachlorocyclohexane, alpha-, Hexachlorocyclohexane, delta-, Hexachlorocyclohexane, gamma-, CCRIS 327, CCRIS 328, CCRIS 329, technical Hexachlorocyclohexane, trans-alpha-Benzenehexachloride, .delta.-HCH, HCH (alpha), Benzenehexachloride-alpha-isomer, CCRIS 1449, HSDB 646, HCH (beta), BBH, d-BHC, Benzene hexachloride (Ambiguous), Benzene hexachloride-gamma isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (-)-alpha-HCH, 1a,2a,3b,4a,5b,6b-Hexachlorocyclohexane, gamma-BHC Benhexachlor, HSDB 1606, HSDB 6029, HSDB 6183, HSDB 6184, Benzenehexachloride, mixed isomers, benzene-cis-hexachloride, NCI-C00204, Hexachlorocyclohexane, gamma isomer, Hexachlorocyclohexane (all isomers), Drill tox-spezial aglukon, Murfume grain store smoke, EINECS 200-401-2, EINECS 206-270-8, EINECS 206-271-3, EINECS 206-272-9, EINECS 210-168-9, epsilon-Benzenehexachloride, Hexachlorocyclohexane (mixed isomers), NSC 11808, 59NEE7PCAB, KWELL (TN), YM80ODM9PD, Hexachlorocyclohexane, technical grade, HGI, RCRA waste no. U129, Benzene Hexachloride, gamma, EPA Pesticide Chemical Code 009001, Hexachlorocyclohexane (technical grade), epsilon-Hexachlorocyclohexane, BRN 1907331, BRN 1907334, BRN 1907337, BRN 1907338, BRN 3195880, .delta.-Benzene hexachloride, UNII-YV2D256Z3N, (1alpha,2beta,3alpha,4beta,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, AI3-07796, AI3-08601, AI3-09232, AI3-09233, AI3-09234, YV2D256Z3N, (1r,2r,3r,4r,5r,6r)-1,2,3,4,5,6-hexachlorocyclohexane, Lindane [Hexachlorocyclohexanes], PLK, benzene hexachloride-gamma-isomer, CHEBI:24536, CHEBI:28428, CHEBI:32888, CHEBI:39095, CHEBI:39096, Benzene hexachloride, all isomers, Cyclohexane, beta-1,2,3,4,5,6-hexachloro-, Cyclohexane, delta-1,2,3,4,5,6-hexachloro-, beta-HCH [Hexachlorocyclohexanes], UNII-IVM9A2N49K, JLYXXMFPNIAWKQ-GNIYUCBRSA-N, alpha-HCH [Hexachlorocyclohexanes], gamma-HCH [Hexachlorocyclohexanes], Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-, 1,2,3,4,5,6-Hexachlorocyclohexane, gamma-isomer, delta-(Aeeeee)-1,2,3,4,5,6-hexachlorocyclohexane, EINECS 228-068-9, HCH-.delta., Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.alpha.,6.beta.)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.beta.,6.beta.)-, BHC-.delta. isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, alpha-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, beta-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, gamma-isomer, 119911-69-2, BHC, .delta., UNII-5477B350EK, 1,2,3,4,5,6-Hexachlorocyclohexane (mixture of isomers), Cyclohexane, 1,2,3,4,5,6-hexachloro-, (mixed isomers), NCGC00094546-04, 1a,2b,3a,4b,5a,6b-hexachlorocyclohexane, (1R,2R,3R,4R,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2R,3S,4s,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane, 1alpha,2alpha,3beta,4alpha,5alpha,6beta-Hexachlorocyclohexane, AI3-15109, trans-1,2,3,4,5,6-hexachlorocyclohexane, DSSTox_CID_685, DSSTox_CID_686, DSSTox_CID_687, 1-alpha,2-alpha,3-alpha,4-beta,5-alpha,6-beta-Hexachlorocyclohexane, 1-alpha,2-beta,3-alpha,4-beta,5-alpha,6-beta-Hexachlorocyclohexane, HCH, technical grade [Hexachlorocyclohexanes], (1alpha,2alpha,3alpha,4beta,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2beta,3alpha,4beta,5alpha,6beta)-, DSSTox_RID_75733, DSSTox_RID_75734, DSSTox_RID_75735, 1,2,3,4,5,6-Hexachlorocyclohexane gamma isomer, DSSTox_GSID_20685, DSSTox_GSID_20686, DSSTox_GSID_20687, 55963-79-6, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.beta.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, 1,2,3,4,5,6-Hexachlorocyclohexane (all stereo isomers), Cyclohexane, 1,2,3,4,5,6-hexachloro-, .gamma.-isomer, (1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2t,3c,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, 1alpha,2alpha,3beta,4alpha,5beta,6beta-Hexachlorocyclohexane, Scabecid, IVM9A2N49K, (1alpha,2alpha,3alpha,4beta,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane, 1,2,3,4,5,6-hexachlorocyclohexane (1alpha,2alpha,3beta,4alpha,5alpha,6beta), 1,2,3,4,5,6-Hexachlorocyclohexane (all stereo isomers, including lindane), gamma-Hexachlorocyclohexane [Lindane and other hexachlorocyclohexane isomers], theta-HCH, CAS-58-89-9, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4beta,5alpha,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4beta,5beta,6beta)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-, Cyclohexane, l,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,4alpha,5beta,6beta)-, 119911-70-5, 6108-11-8, 6108-12-9, CAS-319-85-7, CAS-608-73-1, SMR000857321, SMR000875266, .alpha.-BHC, .gamma.-BHC, 1,2,3,4,5,6-Hexachlorocyclohexane (HCH), .delta.,1,2,3,4,5,6-Hexachlorocyclohexane, 5477B350EK, Cyclohexane, .delta.,1,2,3,4,5,6-hexachloro-, SR-05000001837, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .delta.-, theta-Hexachlorocyclohexane, .delta.-(aeeee)-1,2,3,4,5,6-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .delta.-isomer, .beta.-Hexachlorocyclohexane, Lindane [USAN:INN:BAN], Kanodane, gamma&raquo, Fumite lindane, Scabene lotion, Detmol Extrakt, gamma-linda ne, H.C.H., Agrocide6G, Nexit Stark, 1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.-Hexachlorocyclohexane, .gamma.-Lindane, Lindane [USAN:USP:INN:BAN], Sang-&laquo, theta-BHC, Hexachlorzyklohexan, Gamma-BHC dust, Gamma-HCH dust, Nexol E, d-alpha-BHC, Sang-.gamma., alpha- BHC, eta-BHC, eta-HCH, 1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, Lindane,(S), alpha-hexacloran(e), BHC |A-isomer, .alpha.-Hexachloran, .gamma.-Hexachloran, .alpha.-HCH, .gamma.-HCH, BHC .alpha., BHCor HCH, HCH-.alpha., .alpha.-Hexachlorane, .gamma.-Hexachlorane, BHC-.alpha. isomer, BHC(.gamma.), G-BHC-.delta., HCH, technical grade, lindane (Gama-HCH), gamma-BHC (lindane), lindane (gamma-HCH), Lindane, 97%, Lindane (USP/INN), beta-Benzenehexachloride, Spectrum_001929, eta-Hexachlorocyclohexane, PS71_SUPELCO, zeta-Hexachlorocyclohexane, .gamma.-Benzohexachloride, .gamma.-Hexachlorobenzene, benzene-trans-hexachloride, DSSTox_CID_684, Hexachlorocyclohexane-Beta, Spectrum2_001864, Spectrum3_000860, Spectrum4_000700, Spectrum5_001586, 1,2,3,4,5,6-HCH, beta-Hexachlorocyclohexanes, DSSTox_CID_4134, Hexachlorocyclohexane-Alpha, beta-Hexac hlorocyclohexane, alpha-Hexachlorocyclohexanes, D0Q5IN, Gamma Benzene Hydrochloride, HCH (BHC) (technical), epsilon-Benzene hexachloride, gamma-:hexachlorocyclohexane, AC1L19VZ, .alpha.-Hexachlorcyclohexane, DSSTox_RID_75732, H.C.H, .alpha.-Benzene hexachloride, .gamma.-Benzene hexachloride, Benzene-1,2,3,4,5,6-hexachloride (Ambiguous), BIDD:PXR0097, DSSTox_GSID_20684, DSSTox_GSID_24134, SCHEMBL25895, SCHEMBL25896, SCHEMBL75689, .gamma.-Hexachlorocyclohexane, BSPBio_002479, KBioGR_001199, KBioSS_002471, SPECTRUM330071, 2-05-00-00011 (Beilstein Handbook Reference), 4-05-00-00056 (Beilstein Handbook Reference), 4-05-00-00058 (Beilstein Handbook Reference), 4-05-00-00060 (Beilstein Handbook Reference), 4-05-00-00061 (Beilstein Handbook Reference), MLS001333088, MLS001335969, MLS001335970, MLS001361319, beta-BHC, analytical standard, BIDD:ER0090, BIDD:ER0091, BIDD:ER0449, BIDD:ER0558, BIDD:GT0634, CHEMBL15891, DivK1c_000701, SCHEMBL140812, SCHEMBL140813, SCHEMBL472088, Benzene Hexachloride, .gamma., SPBio_001708, .epsilon.-Hexachlorocyclohexane, delta-BHC, analytical standard, gamma-BHC, analytical standard, CHEMBL389022, Hexachlorocyclohexane, Technical, SCHEMBL7647849, SCHEMBL8469477, SCHEMBL9120917, ZINC1621, CHEMBL1200921, CHEMBL1714528, CHEMBL1874247, CHEMBL2272381, Hexachlorocyclohexane (q-isomer), Hexachlorocyclohexane (z-isomer), Hexachlorocyclohexane [h-isomer], SCHEMBL10795898, HMS502D03, KBio1_000701, KBio2_002464, KBio2_005032, KBio2_007600, KBio3_001979, BHC (alpha-, beta-, gamma-), NSC7909, NSC8093, JLYXXMFPNIAWKQ-GPIVLXJGSA-N, JLYXXMFPNIAWKQ-LKPKBOIGSA-N, JLYXXMFPNIAWKQ-UHFFFAOYSA-N, NINDS_000701, HMS1923K17, HMS2091E05, HMS2230C24, HMS2231A06, HMS3369J21, Pharmakon1600-00330071, GAMMA-HEXACHLORO-CYCLOHEXANE, Benzene hexachloride-.alpha.-isomer, cpd with unspecified stereochemistry, HY-A0085, NSC-7909, NSC-8093, NSC11807, NSC11808, a-Hexachlorocyclohexane (HCH, BHC), Benzene Hexachloride (gamma-Isomer), Hexachlorocyclohexane,.gamma.-isomer, Tox21_111294, Tox21_200676, Tox21_201777, Tox21_202069, Tox21_202290, Tox21_300624, Tox21_300953, Tox21_302925, Tox21_303873, 7644AF, BDBM50410525, beta-HCH 100 microg/mL in Toluene, CCG-39862, LS-242, MFCD00135947, NSC-11807, NSC-11808, NSC755895, SBB061412, AKOS015903494, AKOS015914103, AKOS024390982, Cyclohexane,2,3,4,5,6-hexachloro-, HEXACHLOROCYCLOHEXANE (MIXTURE), ZINC100068484, ZINC100076865, ZINC100076868, ZINC100899052, ZINC245204924, ZINC263584078, beta-HCH 10 microg/mL in Cyclohexane, DB00431, FCH1320285, LS-7424, LS-7425, LS-7426, NSC-755895, (1alpha,2alpha,3alpha,4alpha,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, alpha-HCH 10 microg/mL in Cyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5alpha,6beta)-, delta-HCH 10 microg/mL in Cyclohexane, epsilon-HCH 100 microg/mL in Methanol, g-1,2,3,4,5,6-Hexachlorocyclohexane, gamma-HCH 10 microg/mL in Cyclohexane, IDI1_000701, (.+/-.)-.alpha.-Hexachlorocyclohexane, alpha-HCH 100 microg/mL in Cyclohexane, Cyclohexane,1,2,3,4,5,6-hexachloro-, delta-HCH 100 microg/mL in Cyclohexane, gamma-HCH 100 microg/mL in Cyclohexane, NCGC00094546-01, NCGC00094546-02, NCGC00094546-03, NCGC00094546-05, NCGC00094546-06, NCGC00094546-07, NCGC00094546-08, NCGC00094546-09, NCGC00094546-10, NCGC00094546-11, NCGC00159386-02, NCGC00159386-03, NCGC00159386-04, NCGC00159386-05, NCGC00163943-01, NCGC00163943-02, NCGC00163943-03, NCGC00163943-04, NCGC00163943-05, NCGC00248792-01, NCGC00254541-01, NCGC00254855-01, NCGC00256383-01, NCGC00258230-01, NCGC00259326-01, NCGC00259618-01, NCGC00259839-01, NCGC00357135-01, 6108-13-0, AC-11679, AN-41770, CAS-319-84-6, CAS-319-86-8, CC-02682, epsilon-HCH 10 microg/mL in Cyclohexane, LS-56881, epsilon-HCH 100 microg/mL in Cyclohexane, SBI-0051430.P003, .delta.,2,3,4,5,6-Hexachlorocyclohexane, KB-147807, Lindane, PESTANAL(R), analytical standard, LS-185311, LS-193399, LS-193400, LS-193401, .alpha.-1,2,3,4,5,6-Hexachlorcyclohexane, FT-0603490, FT-0606175, FT-0647466, ST51047431, V0158, WLN: L6TJ AG BG CG DG EG FG .delta., .alpha.-1,2,3,4,5,6-Hexachlorocyclohexane, .gamma.-1,2,3,4,5,6-Hexachlorocyclohexane, 1,2,3,4,5,6-.gamma.-Hexachlorocyclohexane, alpha-HCH, PESTANAL(R), analytical standard, beta-HCH, PESTANAL(R), analytical standard, delta-HCH, PESTANAL(R), analytical standard, C06988, C07075, C15214, C18738, D00360, 1,2,3,4,5,6-Hexachlorocyclohexane (.gamma.), 1,3,4,5,6-Hexachlorcyclohexane, .beta. isomer, AB00052031_02, Cyclohexane,2,3,4,5,6-hexachloro-, .delta.-, 1,2,3,4,5,6-hexachlorocyclohexane, alpha isomer, 1,3,4,5,6-Hexachlorocyclohexane, .gamma. isomer, 135764-EP2275422A1, 135764-EP2292608A1, alpha-1,2,3,4,5,6-Hexachlorocyclohexane, 99%, Benzene-1,2,3,4,5,6-hexachloride ((Ambiguous), C-18255, Cyclohexane, .alpha.-1,2,3,4,5,6-hexachloro-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta-, .delta.-(aeeee)-1,3,4,5,6-Hexachlorocyclohexane, 1,2,3,4,5,6-Hexachlorocyclohexane (gamma-Isomer), 1|A,2|A,3|A,4|A,5|A,6|A-Hexachlorocyclohexane, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .alpha.-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .beta.-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, .gamma.-, HCH (BHC) (technical) 10 microg/mL in Isooctane, J-018587, J-018588, J-018589, LINDANE (BENZENE HEXACHLOROIDE-GAMMA ISOMER), SR-05000001837-1, SR-05000001837-4, Cyclohexane,2,3,4,5,6-hexachloro-, .delta.-isomer, I14-19248, I14-45278, alpha-HCH Solution, 100 mg/mL, (RM, ISO Guide 34), Cyclohexane, 1,2,3,4,5,6-hexachloro-, .alpha.-isomer, Cyclohexane, 1,2,3,4,5,6-hexachloro-, delta- (8CI), UNII-5477B350EK component JLYXXMFPNIAWKQ-CDRYSYESSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-GNIYUCBRSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-LKPKBOIGSA-N, UNII-5477B350EK component JLYXXMFPNIAWKQ-SHFUYGGZSA-N, UNII-IVM9A2N49K component JLYXXMFPNIAWKQ-LKPKBOIGSA-N, UNII-IVM9A2N49K component JLYXXMFPNIAWKQ-SHFUYGGZSA-N, (1r,2c,3c,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2c,3t,4c,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1r,2c,3t,4t,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1R,2r,3S,4R,5s,6S)-1,2,3,4,5,6-hexachlorocyclohexane, (1s,2R,3R,4s,5S,6S)-1,2,3,4,5,6-hexachlorocyclohexane, Lindane, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6, Lindane, Pharmaceutical Secondary Standard; Certified Reference Material, (1.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,3.beta.,4.alpha.,5.alpha.,6.beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3alpha,4alpha,5alpha,6alpha)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3alpha,4alpha,5beta,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane, (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5, 6-hexachlorocyclohexane, (1alpha,2alpha,3beta,4beta,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane, 1-.alpha.,2-.alpha.,3-.beta.,4-.alpha.,5-.beta.,6-.beta.-Hexachlorocyclohexane, beta-HCH solution, 100 mug/mL in methanol, PESTANAL(R), analytical standard, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5alpha,6alpha)-, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3alpha,4alpha,5beta,6beta)-, 1,2,3,4,5,6-Hexachlorocyclohexane, (1.alpha.,2.alpha.,3.beta.,4.alpha.,5.beta.,6.beta.)-, 20437-97-2, 25897-48-7, 39284-22-5, 53529-37-6, 60291-32-9, 8007-42-9, 8073-23-2, 89609-19-8, Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.beta.,6.beta.)-, Cyclohexane,2,3,4,5,6-hexachloro-, (1.alpha.,2.alpha.,3.alpha.,4.beta.,5.alpha.,6.beta.)-, HCH, PESTANAL(R), analytical standard, mixture of isomers (alpha:beta:gamma:delta=1:1:1:1)

ID: 1086

InChIKey: JLZAERUVCODZQO-UGOWOXHDSA-N
SMILES: CC(=O)OC1CC[C@@]2(C3CC[C@@]4(C(CC[C@@]4(C3CC[C@@]2(C1)O)O)C5=CC(=O)OC5)C)C=O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"KA Teske" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile"

CID is 44135347
synonyms found at PubChem are:
ACETYL STROPHANIDIN

ID: 1087

InChIKey: JMFRWRFFLBVWSI-NSCUHMNNSA-N
SMILES: COC1=C(C=CC(=C1)/C=C/CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1549095
synonyms found at PubChem are:
CONIFERYL ALCOHOL, 458-35-5, Coniferol, Coniferylalcohol, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenol, gamma-Hydroxyisoeugenol, trans-Coniferyl alcohol, (E)-Coniferyl alcohol, 4-(3-Hydroxy-1-propenyl)-2-methoxyphenol, 3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol, 32811-40-8, 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenol, 4-Hydroxy-3-methoxycinnamic alcohol, 4-Hydroxy-3-methoxycinnamyl alcohol, Coniferylic alcohol, E-Coniferyl alcohol, UNII-E7SM92591P, CHEBI:17745, 4-[(1E)-3-Hydroxy-1-propenyl]-2-methoxyphenol, JMFRWRFFLBVWSI-NSCUHMNNSA-N, E7SM92591P, p-Hydroxy-m-methoxycinnamyl alcohol, 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-Hydroxy-3-methoxyphenyl)allyl alcohol, Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-, 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxyphenol, 4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenol, 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl), (E)-, 4-hydroxy-3-methoxy cinnamyl alcohol, 4-Hydroxy-3-methoxycinnamylic alcohol, 4-[3-Hydroxy-1-propenyl]-2-methoxyphenol, Coniferyl alcohol, E-, Coniferyl alcohol [MI], trans-coniferol, CONIFERYL-ALCOHOL, epsilon-coniferyl alcohol, AC1LU7QR, .gamma.-Hydroxyisoeugenol, Coniferyl alcohol, 98%, Phenol, 4-(3-hydroxy-1-propen-1-yl)-2-methoxy-, bmse000602, bmse010248, bmse010285, Epitope ID:116871, 4-(3-Hydroxy-1-propen-1-yl)-2-methoxyphenol, SCHEMBL177683, CHEMBL501870, DTXSID50186489, 4e70, JMFRWRFFLBVWSI-UHFFFAOYSA-N, MolPort-001-785-894, ZX-AT000357, 6307AB, MFCD00002922, ZINC12359045, AKOS005258118, FCH1115179, FCH4635646, OR24816, PS-4366, AJ-61355, AK122279, BBV-41802105, CC-25964, KB-76158, ST098738, AX8012054, DB-051336, KB-186780, RT-000096, 4-(3-hydroxy-1-propenyl)-2-methoxy-Phenol, ST24042895, 3-(4-Hydroxy-3-methoxyphenyl)prop-2-en-1-ol, C00590, (E)-4-(3-hydroxyprop-1-enyl)-2-methoxyphenol, 2-methoxy-4-[(E)-3-oxidanylprop-1-enyl]phenol, (E)-4-(3 -hydroxyprop-1-enyl)-2-methoxyphenol, 4-((1E)-3-hydroxyprop-1-enyl)-2-methoxyphenol, 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxy-phenol, A826901, (E) 3-(4-hydroxy-3-methoxyphenyl)-2-Propen-1-ol, I06-0311, Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-, (E)-, F8420572-6986-4EF3-917B-3298FD384F2C

ID: 1088

InChIKey: JMPKPWBLQUWFHQ-LUAGPVBASA-N
SMILES: C(C[N+](=O)[O-])C(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)OC(=O)CC[N+](=O)[O-])OC(=O)CC[N+](=O)[O-])OC(=O)CC[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6710740
synonyms found at PubChem are:
ENDECAPHYLLIN X, Spectrum2_000806, Spectrum3_001209, AC1O8K0A, BSPBio_002598, SPECTRUM211152, SPBio_000671, CHEMBL3039295, CHEBI:92961, KBio3_002098, CCG-39540, NCGC00178584-01, BRD-K54728231-001-02-3, beta-D-Glucopyranose 2,3,4,6-tetrakis(3-nitropropanoate), [(2R,3R,4S,5R,6R)-6-hydroxy-3,4,5-tris(3-nitropropanoyloxy)oxan-2-yl]methyl 3-nitropropanoate

ID: 1089

InChIKey: JMQMNWIBUCGUDO-WHFBIAKZSA-N
SMILES: C([C@@H](C(=O)O)N)SCSC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68134
synonyms found at PubChem are:
Djenkolic acid, L-Djenkolic acid, 498-59-9, Djenkolate, L-Djenkolate, UNII-3QHC9R0YFZ, beta,beta'-Methylenedithiodialanine, L-Cysteine thioacetal of formaldehyde, 3,3'-(Methylenedithio)dialanine, S,S'-Methylenebiscysteine, 3QHC9R0YFZ, CHEBI:6211, 3,3'-Methylenedithiobis(2-aminopropanoic acid), Alanine, 3,3'-(methylenedithio)di-, Jengkolic acid, EINECS 207-863-4, NSC 76076, AC1Q5QNS, S,S'-methylenebis(cysteine), s,s'-methylenebis-l-cysteine, S,S'-Methylenedi-L-cysteine, SCHEMBL151396, AC1L293S, S,S'-methylene-bis-L-cysteine, CHEMBL3138615, C7H14N2SO42, CTK4J1781, BID1201, DTXSID80198075, ZX-AFC001017, ZINC1531043, 7783AF, AKOS030538008, API0003139, L-Cysteine, S,S'-methylenebis- (9CI), D0961, FT-0772324, C08275, Alanine, 3,3'-(methylenedithio)di-, L- (8CI), I14-61957, (2R,2'R)-3,3'-(methylenedisulfanediyl)bis(2-aminopropanoic acid), (2R,2'R)-3,3'-methylenebis(sulfanediyl)bis(2-aminopropanoic acid), (2R)-2-amino-3-[[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanylmethylsulfanyl]propanoic acid, CJ-24079

ID: 1090

InChIKey: JMTYYLMGSBSPPK-UHFFFAOYSA-N
SMILES: C1CCC(CC1)[Si](CCCN2CCCCC2)(C3=CC=C(C=C3)F)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957564
synonyms found at PubChem are:
p-Fluorohexahydro-sila-difenidol hydrochloride, P-F-HHSiD hydrochloride, Hexahydro-sila-difenidol hydrochloride, p-fluoro analog, EU-0100608, Hexahydro-Sila-Difenidol HCl, MLS002172447, CHEMBL1256647, Tox21_500608, CCG-221912, LP00608, NCGC00093983-01, NCGC00261293-01, SMR001254082, RT-014898, H-127, p-fluoro-hexahydro-sila-difenidol hydrochloride, SR-01000075319, J-003472, SR-01000075319-1, Cyclohexyl-(4-fluorophenyl)-(3-N-piperidinopropyl)silanol hydrochloride, p-Fluorohexahydro-sila-difenidol hydrochloride, powder, >=98% (HPLC), 175615-76-6, Hexahydro sila difenidol hydrochloride

ID: 1091

InChIKey: JMVIGOFRIJJUAW-HRFVKAFMSA-N
SMILES: C1[C@H](N[C@@H]1C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6604769
synonyms found at PubChem are:
trans-Azetidine-2,4-dicarboxylic acid, 161596-62-9, (2S,4S)-azetidine-2,4-dicarboxylic acid, (2S,4S)-(-)-Azetidine-2,4-dicarboxylic acid, tADA, (+/-)-trans-azetidine-2,4-dicarboxylic acid, Tocris-0860, AC1O7GUS, Lopac0_000099, CHEMBL43528, SCHEMBL179767, CTK0H6586, DTXSID80424982, ZINC2560277, AKOS022180335, CCG-204194, LP00099, NCGC00024830-01, NCGC00024830-02, NCGC00024830-03, NCGC00024830-04, NCGC00024830-05, AJ-40533, 2,4-Azetidinedicarboxylicacid, (2S,4S)-, RT-011094, A-244, CS-0056957, EU-0100099, (2S,4S)-Azetidine-2alpha,4beta-dicarboxylic acid, SR-01000075426, SR-01000597430, 2,4-Azetidinedicarboxylic acid, (2S,4S)- (9CI), J-009846, SR-01000075426-1, SR-01000597430-1

ID: 1092

InChIKey: JMVIGOFRIJJUAW-WSOKHJQSSA-N
SMILES: C1[C@@H](N[C@@H]1C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2733517
synonyms found at PubChem are:
cis-Azetidine-2,4-dicarboxylic acid, 121050-04-2, 2,4-Azetidinedicarboxylicacid, (2R,4S)-rel-, Biomol-NT_000214, AC1MBZ33, Lopac0_000089, CHEMBL41680, BPBio1_001300, SCHEMBL1321720, CTK4B2155, JMVIGOFRIJJUAW-WSOKHJQSSA-N, ZINC2567368, cis azetidine-2,4-dicarboxylic acid, AKOS006358662, CCG-204184, LP00089, NCGC00093592-01, NCGC00093592-02, NCGC00093592-03, NCGC00093592-04, (4S,2R)azetidine-2,4-dicarboxylic acid, (2R,4S)-azetidine-2,4-dicarboxylic acid, (2S,4R)-azetidine-2,4-dicarboxylic acid, A-243, EU-0100089, FT-0604657, FT-0604675, ST50823958, 2,4-Azetidinedicarboxylicacid,(2R,4S)-rel-, (2R,4S)-Azetidine-2beta,4beta-dicarboxylic acid, SR-01000075425, SR-01000075425-1, 2,4-Azetidinedicarboxylic acid, (2R,4S)-rel- (9CI)

ID: 1093

InChIKey: JNELGWHKGNBSMD-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 7020
synonyms found at PubChem are:
XANTHONE, 9H-Xanthen-9-one, 90-47-1, Xanthen-9-one, 9-Xanthenone, Benzophenone oxide, 9-Oxoxanthene, Genicide, Xanthenone, 9-Xanthone, Diphenylene ketone oxide, Dibenzo-gamma-pyrone, Xanthene, 9-oxo-, 9H-Xanthene, 9-oxo-, Caswell No. 905, UNII-9749WEV0CA, NSC 14978, Dibenzo-.gamma.-pyrone, diphenyline ketone oxide, EINECS 201-997-7, EPA Pesticide Chemical Code 086503, AI3-00077, 9749WEV0CA, CHEMBL186784, E 6, CHEBI:37647, JNELGWHKGNBSMD-UHFFFAOYSA-N, NSC14978, ST024714, 9-oxo-xanthene, xanthene-9-one, Xanthone (Genicide), Xanthone, 97%, AC1L1NTM, Spectrum2_000052, Spectrum3_001884, DSSTox_CID_1795, ACMC-209r6d, Xanthone, 99% 25g, DSSTox_RID_76331, DSSTox_GSID_21795, SCHEMBL41161, BSPBio_003388, SPECTRUM200523, KSC486O8J, MLS002207109, SPBio_000203, ghl.PD_Mitscher_leg0.1212, DTXSID6021795, CTK3I6784, KBio3_002891, KS-00000UQW, WLN: T C666 BO IVJ, MolPort-001-759-220, HMS3651G22, BCP21155, STR05546, ZINC3860823, Tox21_301151, ANW-39491, BDBM50155411, CCG-38356, NSC-14978, s2372, SBB069491, STK372481, AKOS001213782, MCULE-8122570588, NE10375, RP25438, RTR-028437, SDCCGMLS-0066462.P001, TRA0014485, CAS-90-47-1, NCGC00095484-01, NCGC00095484-02, NCGC00095484-03, NCGC00255049-01, AN-42523, R895, SC-75486, SMR000112239, LS-162426, TR-028437, FT-0645039, A843557, AC-907/21098006, SR-05000002437, S14-0934, SR-05000002437-1, W-100331, F8889-9282, Xanthone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8, N-methyl-1-[5-({[(4-methylbenzyl)amino]carbonyl}amino)pyridin-2-yl]piperidine-4-carboxamide

ID: 1094

InChIKey: JNENSSREQFBZGT-UHFFFAOYSA-N
SMILES: C1CN=C2C3=CC=CC=C3SC(=N)N2C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6603967
synonyms found at PubChem are:
PD 404,182, PD-404182, 72596-74-8, UNII-3PYK7K517E, 3PYK7K517E, 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine, 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine, 6H-6-Imino-(2,3,4,5-tetrahydropyrimido)[1,2-c]-[1,3]benzothiazine, NCGC00015809-01, Lopac-P-2742, AC1O7G5X, Lopac0_000947, CHEMBL595227, SCHEMBL4097420, AOB5965, DTXSID00424969, JNENSSREQFBZGT-UHFFFAOYSA-N, MolPort-003-959-210, ZINC3993826, 2H,6H-Pyrimido(1,2-C)(1,3)benzothiazin-6-imine, 3,4-dihydro-, AKOS025293487, CCG-205028, NCGC00015809-02, NCGC00015809-03, NCGC00094251-01, NCGC00094251-02, PD 404182, EU-0100947, P 2742, PD 404,182, >=98% (HPLC), SR-01000076065, SR-01000076065-1, BRD-K14798637-001-01-7

ID: 1095

InChIKey: JNMRHUJNCSQMMB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NC=CS2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5340
synonyms found at PubChem are:
sulfathiazole, 72-14-0, Sulphathiazole, Sulfathiazol, Sulfanilamidothiazole, 2-Sulfanilamidothiazole, Norsulfazole, 2-Sulfonamidothiazole, Norsulfasol, Thiazamide, Neostrepsan, Sulfocerol, Thiozamide, 2-Sulfanilamidothiazol, Sulzol, 2-(Sulfanilylamino)thiazole, Azoquimiol, Azoseptale, Norsulfazol, Poliseptil, Sanotiazol, Sulfathiazolum, Sulfatiazol, Thiacoccine, Thiasulfol, Wintrazole, Cerazole, Chemosept, Cibazol, Eleudron, Estafilol, Planomide, Septozol, Duatok, Dulana, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide, Coco-Thiazole, 2-(p-Aminobenzenesulfonamido)thiazole, Formosulfathiazole, Streptosilthiazole, N(1)-2-Thiazolylsulfanilamide, Sulfamul, Usaf sn-9, Cerazol (suspension), 2-(p-Aminobenzenesulphonamido)thiazole, 4-Amino-N-2-thiazolylbenzenesulfonamide, Norsulfazolum, Ciba 3714, Benzenesulfonamide, 4-amino-N-2-thiazolyl-, Solfatiazolo [DCIT], Caswell No. 809B, 4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide, M&B 760, RP 2090, UNII-Y7FKS2XWQH, 4-Amino-N-thiazol-2-yl-benzenesulfonamide, 2090 R.P., Sulfathiazol [INN-French], Sulfatiazol [INN-Spanish], N1-2-Thiazolylsulfanilamide, Sulfathiazolum [INN-Latin], CCRIS 765, M+B 760, CHEBI:9337, N1-(2-Thiazolyl)sulfanilamide, 2090 rp, 2-Sulfanilamidothiazol [German], Sulfanilamide, N1-2-thiazolyl-, 4-Amino-N-(1,3-Thiazol-2-Yl)Benzene-1-Sulfonamide, HSDB 4380, N(sup 1)-2-Thiazolylsulfanilamide, Y7FKS2XWQH, Sulfanilamide, N(1)-2-thiazolyl-, EINECS 200-771-5, NSC 31812, 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CHEMBL437, EPA Pesticide Chemical Code 077903, NSC 683531, Sulfanilamide, N(sup 1)-2-thiazolyl-, 4-Amino-N-2-thiazolyl-benzenesulfonamide, AI3-01050, N'-(2-Thiazolyl)sulfanilamide, JNMRHUJNCSQMMB-UHFFFAOYSA-N, N(sup1)-(2-Thiazolyl)sulfanilamide, NSC683531, Sulfanilamide, N(sup1)-2-thiazolyl-, CAS-72-14-0, NCGC00016309-02, NCGC00016309-06, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, DSSTox_CID_6068, DSSTox_RID_78004, DSSTox_GSID_26068, [(4-Aminophenyl)sulfonyl]-1,3-thiazol-2-ylamine, Solfatiazolo, SR-05000001722, Sulfathiazole [USAN:INN], sulfthiazole, Enterobiocine, Sulfavitina, Cerazol, Neo-Strepsan, Sulfathiazole [USP:INN:BAN], 2-Sulfathiazole, Sulfathiazole(ST), YTZ, Prestwick_430, Spectrum_001000, Prestwick0_000016, Prestwick1_000016, Prestwick2_000016, Prestwick3_000016, Spectrum2_000841, Spectrum3_001729, Spectrum4_000348, Spectrum5_001441, Sulfathiazole (USP/INN), N-2-Thiazolylsulfanilamide, Epitope ID:122234, AC1L1K4W, AC1Q51XN, Cambridge id 5251400, cid_5340, Oprea1_105970, Oprea1_297844, SCHEMBL94165, BSPBio_000051, BSPBio_003378, KBioGR_000755, KBioSS_001480, KSC917Q1B, MLS002154174, N-1-2-Thiazolylsulfanilamide, DivK1c_000560, SPECTRUM1500553, SPBio_000821, SPBio_001972, ARONIS018158, BPBio1_000057, WLN: T5N CSJ BMSWR DZ, DTXSID8026068, CTK8B7810, HMS501L22, KBio1_000560, KBio2_001480, KBio2_004048, KBio2_006616, KBio3_002598, KS-00004AEL, MolPort-000-488-590, N(sup1)-2-Thiazolylsulfanilamide, NINDS_000560, HMS1568C13, HMS1921C07, HMS2092K09, HMS2095C13, HMS2259A13, HMS3652A03, HMS3712C13, Pharmakon1600-01500553, ZINC121458, HY-B0507, KS-00000H3L, NSC31812, SULFATHIAZOLE (TRIPLE SULFA), Tox21_110363, Tox21_202243, Tox21_303238, ANW-58669, BDBM50027796, CCG-40296, MFCD00005319, NSC-31812, NSC757331, s3116, SBB000946, STK043870, 2-(4-Aminobenzenesulfonamido)thiazole, AKOS000108630, Tox21_110363_1, 144-74-1 (mono-hydrochloride salt), CS-2708, DB06147, LS-1612, MCULE-1370710137, NE10395, NSC-683531, NSC-757331, RTR-023622, SDCCGMLS-0065585.P001, IDI1_000560, NCGC00016309-01, NCGC00016309-03, NCGC00016309-04, NCGC00016309-05, NCGC00016309-07, NCGC00016309-08, NCGC00016309-09, NCGC00016309-10, NCGC00016309-14, NCGC00091133-01, NCGC00091133-02, NCGC00091133-03, NCGC00091133-04, NCGC00257187-01, NCGC00259792-01, Sulfanilamide, N1-2-thiazolyl- (8CI), 2090 R.P, AC-12783, AJ-11762, AN-23809, BAS 00836087, DS-17245, K225, KB-97591, NCI60_002730, SC-77388, SMR000017368, ST011910, ZB004177, 4-Amino-N-(thiazol-2-yl)benzenesulfomide, SBI-0051527.P004, Sulfanilamide, N1-4-thiazolin-2-ylidene-, KB-224306, TR-023622, 4-amino-N-(thiazol-2-yl)-benzenesulfonamide, AB00052102, BB 0245015, FT-0631310, S0272, ST24028888, Sulfathiazole 100 microg/mL in Acetonitrile, 4-[(1,3-Thiazol-2-yl)aminosulfonyl]aniline, Sulfathiazole, analytical standard, >=98.0%, 9610-EP2295053A1, 9610-EP2308872A1, 9610-EP2316829A1, C11169, D01047, AB00052102_14, AB00052102_15, Sulfathiazole, VETRANAL(TM), analytical standard, 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide #, I06-0506, Q-201765, SR-05000001722-1, SR-05000001722-3, Sulfathiazole, Antibiotic for Culture Media Use Only, BRD-K14705039-001-05-7, BRD-K14705039-001-08-1, I14-38050, F1443-4816, Sulfathiazole, European Pharmacopoeia (EP) Reference Standard, Sulfathiazole, United States Pharmacopeia (USP) Reference Standard, 72-14-0,6052-33-1,158269-46-6,144-74-1(sodiumsalt), 158269-46-6, 6052-33-1, 859037-27-7

ID: 1096

InChIKey: JNNGEAWILNVFFD-CDJYTOATSA-N
SMILES: C[C@H]1[C@H](C[C@H]2[C@@H]1[C@@H](OC=C2C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 89640
synonyms found at PubChem are:
Loganic acid, 22255-40-9, Loganate, CHEBI:30632, (1S,4aS,6S,7R,7aS)-1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, Loganic-acid, EINECS 244-875-9, C16H24O10, Spectrum_001509, SpecPlus_000543, AC1L3IAO, Spectrum2_001971, Spectrum3_001930, Spectrum4_001690, Spectrum5_000340, BSPBio_003530, KBioGR_001960, KBioSS_001989, DivK1c_006639, SCHEMBL308008, SPECTRUM1504071, SPBio_002121, CHEMBL1081585, KBio1_001583, KBio2_001989, KBio2_004557, KBio2_007125, KBio3_002760, MolPort-003-665-719, ZINC3978795, CCG-39437, MFCD00017417, AKOS032962058, MCULE-6569288361, SDCCGMLS-0066805.P001, Loganic acid, >=95% (LC/MS-ELSD), NCGC00178007-01, NCGC00178007-02, CC-30020, N2320, W1725, C01512, 255L409, C-21260, W-107488, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid, (1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha))-1-(beta-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta(c)pyran-4-carboxylic acid, Cyclopenta[c]pyran-4-carboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-,(1S,4aS,6S,7R,7aS)-, EQV

ID: 1097

InChIKey: JOAHPSVPXZTVEP-QGPMSJSTSA-N
SMILES: CCN(CC)C(=O)N[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957722
synonyms found at PubChem are:
R(+)-Terguride, NCGC00094476-03, Biomol-NT_000081, Lopac0_001234, BPBio1_001406, CHEMBL1480516, CHEBI:92105, CCG-205308, NCGC00094476-01, NCGC00094476-02, EU-0101234, T-165, N-(6-Methylergolin-8beta-yl)-N',N'-diethylurea, SR-01000076220, SR-01000076220-1, BRD-K05901394-001-01-1, R(+)-N,N-Diethyl-N'[(8alpha)-6-methylergolin-8-yl]urea, 88293-83-8

ID: 1098

InChIKey: JOHZPMXAZQZXHR-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4831
synonyms found at PubChem are:
pipemidic acid, 51940-44-4, Deblaston, Pipram, Palin, Acido pipemidico, Acide pipemidique, Acidum pipemidicum, Pipedac, Pipemid, Uromidin, Dolcol, UNII-LT12J5HVR8, Acido pipemidico [Spanish], 1489 RB, RB 1489, Acide pipemidique [INN-French], Acido pipemidico [INN-Spanish], Acidum pipemidicum [INN-Latin], 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid, EINECS 257-530-2, BRN 0626575, LT12J5HVR8, 5,8-Dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid, MLS000028608, CHEBI:75250, piperamic acid, C14H17N5O3, Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, NCGC00016866-01, SMR000058711, CAS-51940-44-4, DSSTox_CID_3479, P-6835, Acide ethyl-8 oxo-5 piperazinyl-2 dihydro-5,8 pyrido(2,3-d)pyrimidine-6 carboxylique [French], DSSTox_RID_77045, DSSTox_GSID_23479, 8-ethyl-5-oxo-2-piperazin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic Acid, 8-ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-(piperazin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazinyl-8-hydropyridino[2,3-d]pyrimidine-6-carboxylic acid, Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)-, Pyrido[2,3-d]pyrimidine-6-carboxylicacid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, SR-01000000245, Pipemidic acid [INN:DCF], pipeacid, uropimid, Pipemidicacid, Pipemidic, CCRIS 8517, Pipemidic acid [INN:BAN:DCF], Nuril (TN), Pipemidic Acid,(S), Pipemidic acid hydrate, Pipemidic acid (INN), Spectrum_001387, Opera_ID_1142, Prestwick0_000897, Prestwick1_000897, Prestwick2_000897, Prestwick3_000897, Spectrum2_001185, Spectrum3_001487, Spectrum4_000155, Spectrum5_001214, AC1L1J1W, AC1Q5RD4, BSPBio_000714, BSPBio_003073, KBioGR_000630, KBioSS_001867, BIDD:GT0126, CHEMBL30116, DivK1c_000651, SCHEMBL135557, SPECTRUM1502024, SPBio_001229, SPBio_002923, AC1Q310B, BPBio1_000786, DTXSID3023479, CTK1G9533, HMS502A13, KBio1_000651, KBio2_001867, KBio2_004435, KBio2_007003, KBio3_002573, ZINC57466, JOHZPMXAZQZXHR-UHFFFAOYSA-N, MolPort-001-839-001, NINDS_000651, HMS1570D16, HMS1921F04, HMS2097D16, HMS3714D16, Pharmakon1600-01502024, BCP13633, HY-B1210, KS-00001FB6, Tox21_110655, MFCD00057291, NSC758160, SBB012523, STK686262, AKOS005599752, Tox21_110655_1, API0003860, CCG-220897, CS-4838, MCULE-8992370691, NSC-758160, Acide ethyl-8 oxo-5 piperazinyl-2 dihydro-5,8 pyrido(2,3-d)pyrimidine-6 carboxylique, IDI1_000651, SMP1_000242, NCGC00016866-02, NCGC00016866-03, NCGC00016866-04, NCGC00016866-05, NCGC00016866-06, NCGC00016866-07, NCGC00016866-08, NCGC00016866-11, NCGC00023999-03, NCGC00023999-04, NCGC00178314-01, NCGC00178314-02, AN-41083, AS-47690, ST072200, SBI-0051703.P002, LS-134084, AB00490004, V0168, A-7387, D08379, AB00052258_14, A828860, SR-01000000245-2, SR-01000000245-3, SR-01000000245-4, BRD-K08999871-001-05-5, BRD-K08999871-001-13-9, Pipemidic acid, Antibiotic for Culture Media Use Only, A3830/0162685, 8-ethyl-5-oxo-2-(1-piperazinyl)-6-pyrido[2,3-d]pyrimidinecarboxylic acid, 2-(1-piperazinyl)-5,8-dihydro-8-ethyl-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 2-(1-piperazinyl)-8-ethyl-5,8-dihydro-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 5,8-Dihydro-8-ethyl-2-(1-piperazinyl)-5-oxopyrido-[2,3-d]pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-2-(1-piperazinyl)-5-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid, 7-(1-Piperazinyl)-1-ethyl-4-oxo-1,4-dihydro-6,8-diazaquinoline-3-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2- [1-piperazinyl]pyrido[2,3-d]- pyrimidine-6-carboxylic acid, 8-Ethyl-5,8-dihydro-5-oxo-2-[1-piperazinyl]pyrido[2,3-d]-pyrimidine-6-carboxylic acid, 8-ethyl-5-oxidanylidene-2-piperazin-1-yl-pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 108911-86-0, AC1OCK1X, 8-ethyl-5-oxo-2-piperazin-4-ium-1-ylpyrido[2,3-d]pyrimidine-6-carboxylate

ID: 1099

InChIKey: JOJPJLHRMGPDPV-LZQROVCBSA-N
SMILES: C1CC1CN2CC[C@]34[C@@H]5C6=C(C[C@]3([C@H]2CC7=C4C(=C(C=C7)O)O5)O)C8=C(N6)[C@H]9[C@@]12CCN([C@@H]([C@@]1(C8)O)CC1=C2C(=C(C=C1)O)O9)CC1CC1.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957626
synonyms found at PubChem are:
nor-Binaltorphimine dihydrochloride, Nor-bni, nor-BNI dihydrochloride, Norbinaltorphimine dihydrochloride, 105618-26-6, 113158-34-2, 4,8:11,15-Dimethano-20H-bisbenzofuro[2,3-a:3',2'-i]dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol,7,12-bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-,(4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)-, EU-0100806, D0K9HE, CHEMBL2374078, MolPort-003-958-934, Tox21_500806, MFCD00069374, AKOS024457633, LP00806, NCGC00094139-01, NCGC00261491-01, nor-Binaltorphimine dihydrochloride, solid, HY-100903, CS-0020573, N 1771, SR-01000075482, SR-01000597959, J-001459, SR-01000075482-1, SR-01000597959-1, 17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino- 7,7'-binorphinan-3,4',14,14'-tetrol dihydrochloride

ID: 1100

InChIKey: JOWUQCJWCRNVMQ-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957705
synonyms found at PubChem are:
SDZ-205,557 hydrochloride, SDZ 205-557 hydrochloride, 137196-67-9, SDZ-205 557 HCL, 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride, 1197334-02-3, JOWUQCJWCRNVMQ-UHFFFAOYSA-N, 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(diethylamino)ethyl ester hydrochloride, EU-0101153, MLS002153305, CHEMBL1256773, MolPort-003-959-508, Tox21_501153, SDZ-205,557 hydrochloride, solid, AKOS024456921, CCG-222457, LP01153, NCGC00015916-02, NCGC00092301-01, NCGC00094416-01, NCGC00261838-01, BC600837, SMR001230722, S-174, SR-01000075581, J-006976, SR-01000075581-1, 1197334-02-3 (SDZ 205557 Hydrochloride), 137196-67-9(SDZ 205557), 2-(DIETHYLAMINO)ETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE, 2-methoxy-4-amino-5-chloro-benzoic acid 2-(diethylamino)-ethyl ester hydrochloride

ID: 1101

InChIKey: JOYRKODLDBILNP-UHFFFAOYSA-N
SMILES: CCOC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5641
synonyms found at PubChem are:
urethane, ETHYL CARBAMATE, 51-79-6, Urethan, Ethylurethane, Ethyl urethane, Carbamic acid, ethyl ester, Carbamic acid ethyl ester, Ethylcarbamate, Pracarbamine, Leucethane, Pracarbamin, Ethyl urethan, Aethylcarbamat, Aethylurethan, O-Ethylurethane, U-Compound, Ethylurethan, Leucothane, Estane 5703, Uretan etylowy, Uretan, Uretano [DCIT], Carbamidsaeure-aethylester, Urethanum, NSC 746, Aethylurethan [German], Aethylcarbamat [German], Ethylester kyseliny karbaminove, ethyl aminoformate, O-Ethyl urethane, Urethanum [INN-Latin], Uretan etylowy [Polish], RCRA waste number U238, Ethyl ester of carbamic acid, X 41, Carbamidsaeure-aethylester [German], o-Ethyl carbamate, Urethane [INN:BAN:DCF], C3H7NO2, CCRIS 619, UNII-3IN71E75Z5, Ethylester kyseliny karbaminove [Czech], A 11032, HSDB 2555, EINECS 200-123-1, NH2COOC2H5, RCRA waste no. U238, AI3-00553, NSC746, CHEBI:17967, Urethane + ethanol (combination), JOYRKODLDBILNP-UHFFFAOYSA-N, 3IN71E75Z5, Aethylurethan (german), NCGC00095041-01, Aethylcarbamat (german), DSSTox_CID_1427, DSSTox_RID_76156, DSSTox_GSID_21427, Uretano, Carbamate, Ethyl, CAS-51-79-6, Urethane [INN:DCF], SR-05000001854, Ethyl carbamate homopolymer, Urethane, INN, Carbamic acid, ethyl ester, homopolymer, Spectrum_001685, Urethane, >=99%, AC1L1KSZ, Spectrum2_000909, Spectrum3_000965, Spectrum4_001082, Spectrum5_001651, ACMC-209kw3, WLN: ZVO2, BSPBio_002569, KBioGR_001464, KBioSS_002165, Urethane, analytical standard, KSC269I5R, ARONIS27009, BIDD:ER0508, DivK1c_000060, SPECTRUM1503304, SPBio_000758, CHEMBL462547, DTXSID9021427, CTK1G9458, HMS500C22, KBio1_000060, KBio2_002165, KBio2_004733, KBio2_007301, KBio3_001789, NSC-746, MolPort-001-785-624, NINDS_000060, Urethane, >=99.0% (GC), HMS1922A10, HMS2093C21, Pharmakon1600-01503304, ZINC901020, HY-B1207, KS-00000H8Z, KS-000048ID, Tox21_111398, Tox21_201761, Tox21_300494, ANW-31345, CCG-39905, MFCD00007966, NSC758452, s4544, STL257390, AKOS000118772, Tox21_111398_1, AN-4992, CS-4731, DB04827, LS-1317, MCULE-1776877276, NSC-758452, RP18512, RTC-061437, TRA0096154, IDI1_000060, NCGC00095041-02, NCGC00095041-03, NCGC00095041-04, NCGC00095041-05, NCGC00095041-06, NCGC00095041-08, NCGC00254522-01, NCGC00259310-01, 26680-22-8, AJ-24326, CJ-04522, KB-51529, SC-16133, ZB015235, SBI-0051812.P002, SBI-0051812.P003, AB1009252, ST2413069, TC-061437, AM20100253, FT-0626365, 6533-EP1441224A2, 6533-EP2270113A1, 6533-EP2270114A1, 6533-EP2272517A1, 6533-EP2272935A1, 6533-EP2274983A1, 6533-EP2275418A1, 6533-EP2277565A2, 6533-EP2277566A2, 6533-EP2277567A1, 6533-EP2277568A2, 6533-EP2277569A2, 6533-EP2277570A2, 6533-EP2277880A1, 6533-EP2280006A1, 6533-EP2281813A1, 6533-EP2287160A1, 6533-EP2287165A2, 6533-EP2287166A2, 6533-EP2289483A1, 6533-EP2292280A1, 6533-EP2292593A2, 6533-EP2292610A1, 6533-EP2292620A2, 6533-EP2295399A2, 6533-EP2295438A1, 6533-EP2298312A1, 6533-EP2298758A1, 6533-EP2298759A1, 6533-EP2298767A1, 6533-EP2298783A1, 6533-EP2299326A1, 6533-EP2302003A1, 6533-EP2302382A2, 6533-EP2302383A2, 6533-EP2305250A1, 6533-EP2305648A1, 6533-EP2305664A1, 6533-EP2305808A1, 6533-EP2308510A1, 6533-EP2309584A1, 6533-EP2314587A1, 6533-EP2316470A2, 6533-EP2377847A1, C01537, K-9500, AB00052344_04, I14-6090, SR-05000001854-1, SR-05000001854-2, BRD-K24297741-001-01-1, Carbamic acid ethyl ester;Ethyl carbamate;Ethylurethane, Z33546369, Carbamic acid ethyl ester; Ethyl carbamate; Ethylurethane, F0001-1333, InChI=1/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5, 121382-27-2

ID: 1102

InChIKey: JPMYFOBNRRGFNO-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281617
synonyms found at PubChem are:
Genkwanin, 437-64-9, Gengkwanin, 4',5-Dihydroxy-7-methoxyflavone, 5,4'-Dihydroxy-7-methoxyflavone, 7-O-Methylapigenin, 7-Methylapigenin, Apigenin 7-methyl ether, Puddumetin, Gonkwanin, UNII-5K3I5D6B2B, 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, 5K3I5D6B2B, CHEMBL210635, CHEBI:75718, 4'',5-dihydroxy-7-methoxyflavone, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one, 4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, 7-Methoxyapigenin, Henquanin, 7'O-methyl-apigenin, ACMC-20amrz, AC1NQYQP, Apigenin-7-methylether, Spectrum_000330, apigenin-7-methyl ether, SpecPlus_000835, Spectrum2_001355, Spectrum3_001401, Spectrum4_001667, Spectrum5_000573, Apigenin 7-O-Methyl Ether, BSPBio_003042, KBioGR_002193, KBioSS_000810, DivK1c_006931, Genkwanin, analytical standard, SCHEMBL866123, SPBio_001569, 4,5-Dihydroxy-7-methoxyflavone, Genkwanin, >=98% (HPLC), CTK4I7720, KBio1_001875, KBio2_000810, KBio2_003378, KBio2_005946, KBio3_002262, DTXSID80195908, JPMYFOBNRRGFNO-UHFFFAOYSA-N, MolPort-003-665-822, 4',5-dihydroxy-7-methoxy flavone, HY-N0731, ZINC5732375, 4'',5-dihydroxy-7-methoxy flavone, BDBM50187658, CCG-38838, LMPK12111018, AKOS015896775, Flavone, 4',5-dihydroxy-7-methoxy-, MCULE-4718928065, NCGC00178332-01, 4CN-1073, ST057642, DB-051163, TC-169190, CS-0009744, FT-0617186, N2092, W1623, 4',5-Dihydroxy-7-methoxyflavone, AldrichCPR, C10046, C-57765, I07-0230, BRD-K29160894-001-02-9, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-chromen-4-one, 5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chromen-4-one, 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one #

ID: 1103

InChIKey: JQJSTVUROJELSR-UHFFFAOYSA-H
SMILES: N.N.N.N.N.N.N.N.N.N.N.N.N.N.O.O.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru+2].[Ru+2].[Ru+2]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16218584
synonyms found at PubChem are:
MFCD00011479, SR-01000076250, 6Cl.O2Ru3.14NH3, Ruthenium Red, Technical grade, degrees +/->> AENo>> iE, MolPort-003-939-248, 5423AF, AKOS024456597, Azane;ruthenium(2+);hexachloride;dihydrate, J-002508, SR-01000076250-2, SR-01000076250-3, Ruthenium Red, for microscopy, >=85% (calc. on dry substance, AT), Ruthenium Red, for microscopy, 85.0-115.0% (calc. on dry basis, AT), triruthenoxane-1,1,3,3,5,5-hexakis(ylium) tetradecaamine hexachloride, CHEBI:34956, [{Ru(NH3)5}(mu-O){Ru(NH3)4}(mu-O){Ru(NH3)5}]Cl6, tetradecaammine-1kappa(5)N,2kappa(5)N,3kappa(4)N-di-mu-oxidotriruthenium hexachloride

ID: 1104

InChIKey: JQPDCKOQOOQUSC-OOZYFLPDSA-N
SMILES: CC(C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 107883
synonyms found at PubChem are:
Dihydrokainic acid, Dihydrokainate, 52497-36-6, Dihydrokainic Acid, Natural, CHEMBL279561, CHEBI:43562, (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid, (3S,4R)-3-(carboxymethyl)-4-(propan-2-yl)-L-proline, (2S,3S,4R)-2-carboxy-4-(1-methylethyl)-3-pyrrolidineacetic acid, (2S,3S,4R)-3-(carboxymethyl)-4-(propan-2-yl)pyrrolidine-2-carboxylic acid, 1ftk, 1xhy, Dihydrokaioic Acid, (3s,4r)-3-(carboxymethyl)-4-isopropyl-l-proline, 2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid, AC1L32XE, AC1Q5R4V, SCHEMBL155919, CTK1H2670, DTXSID20200489, MolPort-003-940-944, HMS3261K11, ZINC3995564, Tox21_500375, BDBM50240399, BN0188, PDSP2_001490, AKOS024456387, CCG-221679, LP00375, VZ31869, NCGC00261060-01, CC-26819, B6208, Dihydrokainic acid, >=98% (HPLC), powder, A829114, C-11499, SR-01000597697, SR-01000597697-1, (3S,4S)-3-(carboxymethyl)-4-(1-methylethenyl)-L-proline, 3-carboxymethyl-4-isopropyl-pyrrolidine-2-carboxylic acid, (2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidinium-2-carboxylate, (2S,3S,4R)-3-(carboxymethyl)-4-isopropylpyrrolidine-2-carboxylic acid, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-yl-2-pyrrolidinecarboxylic acid, (2S,3S,4R)-3-(carboxymethyl)-4-propan-2-ylpyrrolidine-2-carboxylic acid, (2S,3S,4R)-4-isopropyl-3-(2-oxido-2-oxoethyl)pyrrolidinium-2-carboxylate, 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethyl)-, (2S,3S,4R)-, 3-Pyrrolidineaceticacid, 2-carboxy-4-(1-methylethyl)-, (2S,3S,4R)-, (2S,3S,4R)-3-(2-hydroxy-2-oxoethyl)-4-propan-2-yl-pyrrolidine-2-carboxylic acid, (2S-(2alpha,3beta,4beta))-2-Carboxy-4-(1-methylethyl)-3-pyrrolidineacetic acid

ID: 1105

InChIKey: JRFKIOFLCXKVOT-UHFFFAOYSA-N
SMILES: C1=CC(=CN=C1)C(=O)NCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 77116
synonyms found at PubChem are:
N-(Hydroxymethyl)nicotinamide, 3569-99-1, Nikomethamide, Bilamid, n-hydroxymethylnicotinamide, Bilizorin, Bilocid, Cholamid, Cholamide, Nicodin, Nicodine, Nicoform, Nikodin, Nikoform, Coloton, Felosan, Isochol, Bidbilan, Savatin, Nicometamide, Biloide, Biobilan, Hydroxymethylnicotinamide, N-(hydroxymethyl)pyridine-3-carboxamide, Nicotinamide, N-(hydroxymethyl)-, 3-Pyridinecarboxamide, N-(hydroxymethyl)-, 3-Pyridinecarboxylic acid hydroxymethylamide, Cholamide (pyridine deriv.), Nicotinsaeurehydroxymethylamid, Nicotinylmethylamide, UNII-1N1YGM997E, N-(Hydroxymethyl)-3-pyridinecarboxamide, EINECS 222-668-4, C 1094, N-Hydroxymethyl-nicotinamide, BRN 0128633, N-(hydroxymethyl)-nicotinamide, 1N1YGM997E, JRFKIOFLCXKVOT-UHFFFAOYSA-N, 3-Pyridinecarboxylic acid N-hydroxymethylamide, Nifoform, Cholamid (TN), Nikoform (TN), Spectrum_000376, ACMC-209iip, SpecPlus_000641, Nicotinylmethylamide,(S), AC1L2SDR, AC1Q7DCY, Spectrum2_001197, Spectrum3_001014, Spectrum4_001142, Spectrum5_001885, Oprea1_521547, Oprea1_687785, BSPBio_002767, KBioGR_001683, KBioSS_000856, MLS002695904, CHEMBL92024, DivK1c_006737, SCHEMBL352358, SPECTRUM2300137, SPBio_001273, Jsp006415, CTK3J3158, JRFKIOFLCXKVOT-UHFFFAOYSA-, KBio1_001681, KBio2_000856, KBio2_003424, KBio2_005992, KBio3_001987, DTXSID20189205, CHEBI:134775, MolPort-001-572-850, ZINC409246, ALBB-023192, KS-000012GY, N-(Hydroxymethyl)nicotinamide, 98%, ANW-28271, CCG-40316, AKOS000121436, AC-6974, AN-9462, MCULE-5606088997, N-(hydroxymethyl)-3-pyridylcarboxamide, VZ33319, NCGC00095786-01, NCGC00095786-02, AJ-22696, LS-96436, M707, SMR001562101, ZB013891, RT-001295, A6230, FT-0629289, R1217, ST24031347, ST45016703, D08051, W-106656, InChI=1/C7H8N2O2/c10-5-9-7(11)6-2-1-3-8-4-6/h1-4,10H,5H2,(H,9,11)

ID: 1106

InChIKey: JRLOEMCOOZSCQP-UHFFFAOYSA-N
SMILES: CCCCCC(C1=CC(=CC=C1)OCC2=NC3=CC=CC=C3C=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5059
synonyms found at PubChem are:
Rev 5901, REV-5901, 101910-24-1, PF 5901, RG 5901, alpha-Pentyl-3-(2-quinolinylmethoxy)benzenemethanol, 1-[3-(quinolin-2-ylmethoxy)phenyl]hexan-1-ol, CHEMBL8747, MLS000069771, REV-901, PF-5901, SMR000058509, alpha-Pentyl-3-[2-quinolinylmethoxy]benzyl alcohol, Benzenemethanol, alpha-pentyl-3-(2-quinolinylmethoxy)-, 1-(3-(quinolin-2-ylmethoxy)phenyl)hexan-1-ol, SR-01000076105, ACMC-20d0wb, Opera_ID_512, UNII-WNW5RYD8MG, WNW5RYD8MG, AC1L1JIU, D0O8ZE, CBiol_001910, Lopac0_001042, BSPBio_001522, KBioGR_000242, KBioSS_000242, MLS001076522, SCHEMBL678489, AC1Q777J, BML2-G04, CHEBI:91821, CTK4A0391, KBio2_000242, KBio2_002810, KBio2_005378, KBio3_000483, KBio3_000484, JRLOEMCOOZSCQP-UHFFFAOYSA-N, MolPort-003-959-456, Bio1_000196, Bio1_000685, Bio1_001174, Bio2_000242, Bio2_000722, HMS1361M04, HMS1791M04, HMS1989M04, HMS2232F10, HMS3370K08, HMS3402M04, HMS3649O15, BDBM50012434, MFCD00211150, AKOS000278774, AKOS032953945, CCG-205119, LP01042, IDI1_033992, SMP2_000318, NCGC00015895-02, NCGC00015895-03, NCGC00015895-04, NCGC00015895-05, NCGC00015895-06, NCGC00094327-01, NCGC00094327-02, NCGC00094327-03, NCGC00094327-04, [3-(1-hydroxyhexyl)phenoxymethyl]quinoline, LS-186839, LS-187501, EU-0101042, 2-[3-(1-hydroxyhexyl)phenoxymethyl]quinoline, R 5523, 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol, Benzenemethanol,a-pentyl-3-(2-quinolinylmethoxy)-, Benzenemethanol, a-pentyl-3-(2-quinolinylmethoxy)-, Benzenemethanol,|A-pentyl-3-(2-quinolinylmethoxy)-, SR-01000076105-2, SR-01000076105-7, Benzenemethanol,alpha-pentyl-3-(2-quinolinylmethoxy)-, BRD-A68281735-001-03-8, (REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol, 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol (RG 5901), 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol(Rev-5901)

ID: 1107

InChIKey: JROGBPMEKVAPEH-GXGBFOEMSA-N
SMILES: CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3068143
synonyms found at PubChem are:
EMETINE DIHYDROCHLORIDE, 316-42-7, Emetine hydrochloride, Emetine, dihydrochloride, Purum, Emetine HCl, Emetine.2HCl, Amebicide, Emetine dihydrochloride hydrate, l-Emetine dihydrochloride, UNII-U52OG12P96, CCRIS 6237, EINECS 206-259-8, 6',7',10,11-Tetramethoxyemetan dihydrochloride, Emetine hydrochloride [USP], AI3-50600, (+-)-Dehydro-2,3-emetine 2HCl [French], U52OG12P96, Emetan, 6',7',10,11-tetramethoxy-, dihydrochloride, Emetine hydrochloride (USP), 2H-Benzo(a)quinolizine, 1,4,6,7,11b-pentahydro-9,10-dimethoxy-3-ethyl-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl)-, dihydrochloride, (+-)-, 6′,7′,10,11-Tetramethoxyemetan, 2HCl, 2H-Benzo(a)quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-(((1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl)methyl)-, dihydrochloride, (2S,3R,11bS)-, SR-01000000081, SR-01000075853, (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine;dihydrochloride, Prestwick_196, (+-)-Dehydro-2,3-emetine 2HCl, AC1MIF4M, DSSTox_CID_558, CAS-316-42-7, DSSTox_RID_75658, DSSTox_GSID_20558, C29H40N2O4.2HCl, CHEMBL493439, SCHEMBL2382445, 483-18-1 (Parent), DTXSID7020558, CTK8F9434, JROGBPMEKVAPEH-GXGBFOEMSA-N, MolPort-027-835-921, ML081, 2H-Benzo(a)quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-(((1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl)methyl)-, hydrochloride (1:2), (2S,3R,11bS)-, Tox21_200397, Tox21_500460, 6776AF, MFCD00149309, AKOS016010179, EMetineHydrochlorideEmetinehydrochloride, CCG-208338, LP00460, LS-1183, NCGC00093874-01, NCGC00257951-01, NCGC00261145-01, 83029-37-2, LS-40251, E0007, EU-0100460, D03985, E 2375, J-018500, SR-01000000081-4, SR-01000075853-1, (2alpha)-6',7',10,11-tetramethoxyemetan dihydrochloride, EMETINE HYDROCHLORIDE (SEE ALSO: EMETINE (CAS 483-18-1), (2S,3R,11bS)-2-(((R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline dihydrochloride, (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine dihydrochloride

ID: 1108

InChIKey: JRRNZNSGDSFFIR-UHFFFAOYSA-M
SMILES: C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6461
synonyms found at PubChem are:
MEPENZOLATE BROMIDE, Cantil, 76-90-4, Cantilaque, Colibantil, Gastropidil, Cantilon, Colopiril, Delevil, Eftoron, Tralanta, Trancolon, Colum, Trokonil, Mepenzolati bromidum, Bromure de mepenzolate, Bromuro de mepenzolato, Mepenzolate (Bromide), JB 340, Glycophenylate, Cantril, Mepenzolati bromidum [INN-Latin], N-Methyl-3-piperidyl benzilate methobromide, Bromure de mepenzolate [INN-French], Mepenzolone Bromide, N-Methyl-3-piperidyl benzilate methyl bromide, Bromuro de mepenzolato [INN-Spanish], Cantil (TN), N-Methyl-3-piperidyldiphenylglycolate methobromide, 3-Hydroxy-1,1-dimethylpiperidinium bromide benzilate, 3-(2-Hydroxy-2,2-diphenylacetoxy)-1,1-dimethylpiperidin-1-ium bromide, Benzilic acid, 1-methyl-3-piperidyl ester methobromide, 1-Methyl-3-piperidyl benzilate methylbromide, Mepenzolate Methylbromide, NSC 4358, EINECS 200-992-7, Mepenzolate bromide [INN:BAN:JAN], mepenzolic acid, bromine salt, 3-((Hydroxydiphenylacetyl)oxy)-1,1-dimethylpiperidinium bromide, Benzilic acid, ester with 3-hydroxy-1,1-dimethylpiperidinium bromide, Piperidinium, 3-hydroxy-1,1-dimethyl-, bromide, benzilate, DSSTox_CID_3252, Piperidinium, 3-((hydroxydiphenylacetyl)oxy)-1,1-dimethyl-, bromide, Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, DSSTox_RID_76941, DSSTox_GSID_23252, 1-Methyl-3-piperidyl benzilate methyl bromide, 3-{[hydroxy(diphenyl)acetyl]oxy}-1,1-dimethylpiperidinium bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate bromide, C21H26NO3, SMR000058832, SR-01000765452, N-methyl-3-piperidylbenzilate methyl bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide, Prestwick_100, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate, 2-(1,1-dimethylpiperidin-1-ium-3-yl)oxy-2-oxo-1,1-diphenylethanolate, 2-[(1,1-dimethylpiperidinium-3-yl)oxy]-2-oxo-1,1-diphenylethanolate, Mepenzolate bromide [USP:INN:BAN:JAN], AC1L1MKX, CAS-76-90-4, NCGC00016314-01, D0FV3V, AC1Q1R9F, C21H26BrNO3, CHEMBL1724, SCHEMBL99030, MLS001076678, MLS002222165, SPECTRUM1500383, CHEBI:6753, DTXSID4023252, HMS501P18, NSC4358, Mepenzolate bromide (JP15/INN), Mepenzolate bromide (JP17/INN), MolPort-003-666-226, HMS1570C07, HMS1920L05, HMS2091B18, HMS2097C07, HMS2231P11, HMS3259O19, HMS3369A20, HMS3714C07, Pharmakon1600-01500383, Piperidinium,1-dimethyl-, bromide, 25990-43-6 (Parent), NSC-4358, Tox21_110367, 1988AC, CCG-40131, NSC757099, AKOS015962135, Tox21_110367_1, AN-6437, API0000641, CS-3578, NC00518, NSC-757099, KS-0000119J, NCGC00094716-01, NCGC00094716-02, NCGC00178896-05, WLN: T6KTJ A1 A1 COVXQR&R &E, AC-15989, AK116470, CPD000058832, HY-17585, SAM002554910, AX8137418, Benzilic acid,1-dimethylpiperidinium bromide, KB-232690, LS-116643, FT-0671006, Piperidinium,1-dimethyl-, bromide, benzilate, D00720, SR-01000765452-2, SR-01000765452-3, 3-(2-hydroxy-2,2-diphenylacetoxy)-1,1-dimethylpiperidinium bromide, 3-[(Hydroxy-diphenylacetyl)oxy]-1,1-dimethylpiperidinium Bromide, Piperidinium, 3-((hydroxydiphenylacetyl)oxy)-1,1-dimethyl-(VAN), (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate bromide, (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate,bromide, 88215-34-3

ID: 1109

InChIKey: JSCUNIPKMPNPFX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)N=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4420318
synonyms found at PubChem are:
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine, CHEMBL97760, 7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol, 286411-09-4, NCGC00015250-01, Lopac-C-5982, D05MCK, AC1O0Y6J, Lopac0_000305, SCHEMBL378998, CTK8E5517, CTK8F7271, HMS3260N12, ZINC8582290, Tox21_500305, BDBM50090697, AKOS028113015, CCG-204400, LP00305, TRA0054236, NCGC00015250-02, NCGC00015250-03, NCGC00015250-04, NCGC00015250-05, NCGC00093754-01, NCGC00093754-02, NCGC00260990-01, 7-chloro-2-phenyl-1,8-naphthyridin-4-ol, 2-Phenyl-7-chloro-1,8-naphthyridine-4-ol, KB-270267, TX-017366, 1,8-Naphthyridin-4-ol,7-chloro-2-phenyl-, EU-0100305, 1,8-Naphthyridin-4-ol, 7-chloro-2-phenyl-, 7-chloro-2-phenyl-1H-1,8-naphthyridin-4-one, C 5982, SR-01000075770, SR-01000075770-1

ID: 1110

InChIKey: JSHLZRQFLJYDSZ-ZVWHLABXSA-N
SMILES: CC(=O)O.C1=CC(=CC=C1C[C@@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5702203
synonyms found at PubChem are:
d[-Arg-2]KYOTORPHAN ACETATE, 74872-77-8, Tyr-D-Arg, AC1NWAUH, SPECTRUM1502182, HMS502M07, DTXSID60420644, [D-Arg2]-Kyotorphin acetate salt, CCG-39591, acetic acid; (2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

ID: 1111

InChIKey: JSJOTZXJKCXWQC-UHFFFAOYSA-N
SMILES: CC(=O)OC1=C2C(=C(C=C1)Cl)C=CC=N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2718
synonyms found at PubChem are:
chloroacetoxyquinoline, 5-chloro-8-acetoxyquinoline, silital, 10173-02-1, KBio1_000423, Spectrum_001695, Spectrum2_000867, Spectrum5_001169, AC1L1EB5, KBioSS_002175, DivK1c_000423, SPECTRUM1503341, SPBio_000913, 5-Chloro-8-quinolinol acetate, AC1Q61B5, SCHEMBL3691077, CHEMBL1450499, HMS501F05, KBio2_002175, KBio2_004743, KBio2_007311, (5-chloroquinolin-8-yl) acetate, NINDS_000423, HMS1922A18, CCG-40312, IDI1_000423, NCGC00095044-01, NCGC00095044-02, BRD-K98737600-001-02-5

ID: 1112

InChIKey: JTQJFSQQHGPLOX-UHFFFAOYSA-N
SMILES: CC1=C2C(=CS1)C(=O)NC3=CC=CC=C3N2C(=O)CN4CCN(CC4)C.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6419995
synonyms found at PubChem are:
Telenzepine dihydrochloride, 147416-96-4, Telenzepine hydrochloride, SR-01000075349, Prestwick_649, AC1O4WHM, 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride, SCHEMBL184401, CHEMBL1257109, CTK8E8464, DTXSID10423564, JTQJFSQQHGPLOX-UHFFFAOYSA-N, MolPort-003-959-660, HMS1568N08, Tox21_501204, BN0514, SK-871, AKOS024456398, API0009943, CCG-220303, CCG-222508, LP01204, NCGC00094451-01, NCGC00261889-01, 4,9-Dihydro-3-methyl-4-[(4-methyl-1-, RT-015896, B6606, EU-0101204, FT-0759736, T-122, C-55154, B-803-32, B-818-03, B-818-04, J-008354, SR-01000075349-1, SR-01000075349-3, SR-01000075349-6, piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride, 1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one dihydrochloride

ID: 1113

InChIKey: JUCNGUOYQGHBJC-UHFFFAOYSA-N
SMILES: COC(=O)COC1=CC(=C(C=C1Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1482
synonyms found at PubChem are:
2,4,5-T Methyl ester, 1928-37-6, 2,4,5-T-methyl, 2,4,5-T-methyl [ISO], Methyl (2,4,5-trichlorophenoxy)acetate, UNII-131049BJ6I, 2,4,5-Trichlorophenoxyacetic acid methyl ester, methyl 2-(2,4,5-trichlorophenoxy)acetate, 2,4,5-T-METHYL ESTER, 2,4,5-trichlorophenoxyacetic acid, methyl ester, Acetic acid, (2,4,5-trichlorophenoxy)-, methyl ester, 131049BJ6I, 2,4,5-T Methyl Ester ((2,4,5-Trichlorophenoxy)acetic Acid Methyl Ester), EINECS 217-669-1, Methyl 2,4,5-trichlorophenoxyacetate, methyl(2,4,5-trichlorophenoxy)acetate, NSC 190451, 2,5-T Methyl ester, Spectrum_001865, SpecPlus_000476, 2,4,5-T methyl, 2,4,5-T-methylester, AC1L1BKU, AC1Q3MOE, Spectrum2_001850, Spectrum3_000838, Spectrum4_000678, Spectrum5_001990, BSPBio_002395, KBioGR_001115, KBioSS_002382, SPECTRUM330046, DivK1c_006572, SPBio_001640, CHEMBL1398384, KBio1_001516, KBio2_002378, KBio2_004946, KBio2_007514, KBio3_001895, DTXSID80172875, JUCNGUOYQGHBJC-UHFFFAOYSA-N, ZINC1732130, CCG-39388, NSC190451, Methyl (2,5-trichlorophenoxy)acetate, AKOS008336757, NSC-190451, NCGC00095768-01, NCGC00095768-02, 2,5-Trichlorophenoxyacetic acid methyl ester, Acetic acid,4,5-trichlorophenoxy)-, methyl ester, 2,4,5-T-methyl ester 10 microg/mL in Cyclohexane, J-012478, Acetic acid, (2,4,5-trichlorophenoxy)-, methylated, (2,4,5-TRICHLOROPHENOXY)ACETIC ACID METHYLESTER, 2,4,5-T methyl ester, PESTANAL(R), analytical standard, Acetic acid, (2,4,5-trichlorophenoxy)-, methyl ester (8CI)(9CI)

ID: 1114

InChIKey: JUEUNEKLNSILBZ-BTJKTKAUSA-N
SMILES: C1CC(C2=NC3=CC=CC=C3C(=C2C1)N)O.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5702779
synonyms found at PubChem are:
AC1NWBYA, (Z)-4-hydroxy-4-oxobut-2-enoate; (4-hydroxy-1,2,3,4-tetrahydroacridin-9-yl)azanium, Prestwick_647, AC1O4WHL, Hydroxytacrine maleate (R,S), 9-amino-1,2,3,4-tetrahydroacridin-4-ol; (Z)-but-2-enedioic acid

ID: 1115

InChIKey: JUQLTPCYUFPYKE-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5074
synonyms found at PubChem are:
ritanserin, 87051-43-2, Tiserton, Ritanserine, Ritanserina, Ritanserinum, R-55667, Ritanserine [French], Ritanserinum [Latin], Ritanserina [Spanish], UNII-145TFV465S, C27H25F2N3OS, 6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, R 55,667, MLS000069360, CHEMBL267777, 6-(2-(4-(Bis(p-fluorophenyl)methylene)-piperidino)ethyl)-7-methyl-5H-thiazolo-(3,2-a)pyrimidin-5-one, CHEBI:64195, JUQLTPCYUFPYKE-UHFFFAOYSA-N, 145TFV465S, 6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one, NCGC00015877-06, SMR000058511, DSSTox_CID_22594, DSSTox_RID_80055, DSSTox_GSID_42594, 5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-[2-[4-(bis(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thia, 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-, 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidyl]ethyl]-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[2,3-b]pyrimidin-5-one, CAS-87051-43-2, SR-01000000024, Ritanserin [USAN:BAN:INN], Ritanserin [USAN:INN:BAN], Ritanserin, powder, Tiserton (TN), 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-[2-[4-[Bis(p-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one, Spectrum_001830, Lopac-R-103, AC1L1JJX, Opera_ID_1609, Ritanserin (USAN/INN), Spectrum2_001560, Spectrum3_001023, Spectrum5_001504, D0K8NW, D0N2OM, GTPL97, AC1Q4NH0, cid_5074, N,N-dialkyl-dipeptidylamines, Lopac0_001083, REGID_for_CID_5074, SCHEMBL49227, BSPBio_002805, KBioSS_002335, MLS001148629, DivK1c_000192, ritanserin serotonin antagonist, SPBio_001440, DTXSID9042594, CTK5F7657, HMS500J14, KBio1_000192, KBio2_002332, KBio2_004900, KBio2_007468, KBio3_002025, MolPort-003-666-486, NINDS_000192, HMS2093E19, HMS2233M22, HMS3263I08, HMS3268O04, HMS3373O19, Pharmakon1600-01503421, ZINC538314, BCP13728, Tox21_110251, Tox21_501083, 3726AC, BDBM50001775, BG0387, CCG-39338, MFCD00069341, NSC758470, AKOS015909799, Tox21_110251_1, API0004083, DB12693, LP01083, NSC-758470, IDI1_000192, NCGC00015877-01, NCGC00015877-02, NCGC00015877-03, NCGC00015877-04, NCGC00015877-05, NCGC00015877-07, NCGC00015877-08, NCGC00015877-09, NCGC00015877-11, NCGC00022447-03, NCGC00022447-04, NCGC00022447-05, NCGC00178460-01, NCGC00261768-01, AJ-23387, AN-16598, CC-34269, SBI-0051053.P003, AX8150457, LS-156826, B6898, EU-0101083, FT-0630948, R-103, KS-00001841, D05738, AB00053288_14, 051R432, C-22775, L001003, SR-01000000024-3, SR-01000000024-4, BRD-K40887525-001-02-9, BRD-K40887525-001-14-4, ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, I14-31889, 6-[2-[4-bis(4-Fluorophenyl)methylene]-1-piperidinyl]-, (+)-6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one, (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 5H-Thiazolo[3,2-a]pyrimidin-5-one,6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-, 6-(2-(4-(Bis(4-fluorophenyl);methylene);piperidin-1-yl);ethyl);-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-(4-(Bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo((3,2-a)pyrimidin-5-one, 6-(2-(4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl)ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one #, 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one, 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin), 6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin), 6-[2-[4-[bis (4-Fluorophenyl)- methylene]-1-piperidinyl]-ethyl]- 5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis (4-Fluorophenyl)-methylene]-1-piperidinyl]-ethyl]-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)-methylene]-1-piperidinyl]-ethyl]-5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)-methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]-pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, E2J

ID: 1116

InChIKey: JVGBTTIJPBFLTE-UHFFFAOYSA-N
SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CC4COC5=CC=CC=C5O4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5268
synonyms found at PubChem are:
Spiroxatrine, 1054-88-2, Spiroxatrinum, Spiroxatrine [INN], SPIROXAMIDE, Spiroxatrine (R 5188), Spiroxatrinum [INN-Latin], Espiroxatrina [INN-Spanish], R 5188, NSC 665322, CHEMBL300555, NSC665322, NCGC00015908-05, 8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one, DSSTox_CID_25198, DSSTox_RID_80744, DSSTox_GSID_45198, Espiroxatrina, 1,3,8-Trianaspiro(4.5)decane-4-one,8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-, 8-(1,4-Benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-trianaspiro(4,5)decane-4-one, 8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one, (+/-)-8-[(2,3-Dihydro-1,4-Benzodioxin-2-yl)Methyl]-1-Phenyl-1,3,8-Triazaspiro [4,5]Decan-4-one, CAS-1054-88-2, SR-01000075579, Biomol-NT_000104, D0MU4A, GTPL53, AC1L1JZ3, Lopac0_001142, BPBio1_001395, SCHEMBL1255303, DTXSID3045198, CHEBI:91845, CTK8G3191, MolPort-003-983-690, HMS2089G17, HMS3263F05, HMS3266D15, Tox21_110260, Tox21_501142, BDBM50020192, BN0501, AKOS024458589, Tox21_110260_1, CCG-205216, LP01142, NSC-665322, NCGC00015908-03, NCGC00015908-04, NCGC00015908-06, NCGC00015908-07, NCGC00015908-08, NCGC00015908-09, NCGC00024696-02, NCGC00024696-03, NCGC00024696-04, NCGC00024696-05, NCGC00261827-01, NCI60_022532, LS-171963, EU-0101142, S-103, R-5188, L001271, J-001433, SR-01000075579-1, SR-01000075579-3, BRD-A72483914-001-01-1, BRD-A72483914-001-02-9, 8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro(4,5)-decan-4-one, 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, ( inverted exclamation markA)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one

ID: 1117

InChIKey: JVKYZPBMZPJNAJ-OQFNDJACSA-N
SMILES: C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 65727
synonyms found at PubChem are:
Solanidine, Solanidin, Solatubin, Solatubine, 22R,25S-Solanidanine, 80-78-4, 22R,25S-Solanidine, Solanid-5-en-3beta-ol, 3-beta-Solanid-5-en-3-ol, Solanid-5-en-3-beta-ol, UNII-W7801OHM8B, CCRIS 6508, EINECS 201-309-5, NSC 76025, BRN 0045370, W7801OHM8B, CHEBI:28374, NSC76025, Solanid-5-en-3.beta.-ol, Solanid-5-en-3-ol, (3.beta.)-, Solanid-5-en-3-ol, (3beta)-, Solanid-5-en-3-ol, Solanid-5-en-3b-ol, 4-21-00-01398 (Beilstein Handbook Reference), SCHEMBL336752, (3beta)-solanid-5-en-3-ol, AC1L23U5, Solanid-5-en-3beta-ol(8CI), CHEMBL1980466, Solanid-5-en-3beta-ol (8CI), 3-b-Solanid-5-en-3-ol(9cl), JVKYZPBMZPJNAJ-OQFNDJACSA-N, 3-beta-Solanid-5-en-3-ol(9cl), Solanid-5-en-3-ol, (3-beta)-, Solanidine, >=97.0% (HPLC), ZINC8220551, LMST01150007, NSC-76025, solanid-5-en-3-ol (ACD/Name 4.0), CC-34501, NCI60_041673, Solanid-5-en-3-ol, (3beta)- (9CI), LS-145586, Solanid-5-en-3-ol, (3-beta)- (9CI), C06543, C-23896

ID: 1118

InChIKey: JWBOIMRXGHLCPP-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4211
synonyms found at PubChem are:
mitotane, Mitotan, 53-19-0, Lysodren, Chlodithane, Chloditan, o,p'-DDD, Khlodithan, Chlodithan, Mitotano, 2,4'-Ddd, 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, Mitotanum, Mitotanum [INN-Latin], o,p'-TDE, 2,4'-Dichlorodiphenyldichloroethane, o,p-Tde, Khloditan, Mytotan, 1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene, NCI-C04933, o,p'-Dichlorodiphenyldichloroethane, ortho,para-DDD, Mitotano [INN-Spanish], 2,4'-Dichlorophenyldichlorethane, o,p-DDD, Opeprim, 1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene, CB313, Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-, DDD, o,p'-, CB 313, NSC 38721, Lysodren (TN), Mitotane [USAN:INN:JAN], 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane, 2-(o-Chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloroethane, C14H10Cl4, CCRIS 4397, 1,1-Dichloro-2,2-bis(2,4'-dichlorophenyl)ethane, HSDB 3240, NSC38721, 1,1-Dichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl)ethane, 2,2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane, EINECS 200-166-6, CB-313, (o,p)-DDD, Mitotane (JAN/USP/INN), BRN 2056007, AI3-07575, 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene, Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-, Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-, Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-, NSC-38721, (2,4'-Dichlorodiphenyl)dichloroethane, NCGC00015226-07, (+-)-1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane, DSSTox_CID_372, C 3010, DSSTox_RID_75548, DSSTox_GSID_20372, 2,4 -Dichlorodiphenyldichloroethane, Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-, (+-)-, ortho,para DDD, CAS-53-19-0, SMR000326696, SR-01000075751, Prestwick_75, Ethane,1-dichloro-, Mitotane (Lysodren), Piprine-DDD, O-, Mitotane [USAN:USP:INN:BAN:JAN], PubChem14974, Spectrum_001959, DDD-o,p', AC1L1HNV, Spectrum2_000916, Spectrum3_000869, Spectrum4_000709, Spectrum5_002060, PS694_SUPELCO, D0Z5OE, (o,p')-DDD, SCHEMBL4040, CHEMBL1670, Lopac0_000251, WLN: GYGYR BG&R DG, BSPBio_002517, KBioGR_001237, KBioSS_002513, SPECTRUM330082, MLS001335899, MLS001335900, MLS002152914, MLS002153233, DivK1c_000703, SPBio_000792, AC1Q3H13, CHEBI:6954, GTPL6957, Mitotane, >=98% (HPLC), DTXSID9020372, 2,4'-DDD, analytical standard, CTK8E2992, HMS502D05, KBio1_000703, KBio2_002505, KBio2_005073, KBio2_007641, KBio3_002017, JWBOIMRXGHLCPP-UHFFFAOYSA-N, MolPort-001-779-578, NINDS_000703, HMS1923K19, HMS2091E07, HMS2232C16, HMS3260D04, HMS3369H10, HMS3655G06, HMS3715H07, Pharmakon1600-00330082, BCP11663, 2,4 inverted exclamation marka-DDD, Tox21_110103, Tox21_302804, Tox21_500251, CCG-40014, LS-185, MFCD00000850, NSC755849, s1732, 1,2-bis(2,4'-dichlorophenyl)ethane, AKOS006028802, Tox21_110103_1, Bristol Myers Squibb Brand of Mitotane, Bristol-Myers Squibb Brand of Mitotane, CS-1500, DB00648, LP00251, MCULE-2068358149, NSC-755849, IDI1_000703, NCGC00015226-02, NCGC00015226-03, NCGC00015226-04, NCGC00015226-05, NCGC00015226-06, NCGC00015226-08, NCGC00015226-09, NCGC00015226-10, NCGC00015226-11, NCGC00015226-12, NCGC00091374-01, NCGC00091374-02, NCGC00091374-03, NCGC00091374-04, NCGC00091374-05, NCGC00091374-06, NCGC00256452-01, NCGC00260936-01, 2,4'-DDD 10 microg/mL in Cyclohexane, AN-41639, AS-11690, HY-13690, NCI60_003688, SC-18530, 2,4'-DDD 100 microg/mL in Cyclohexane, SBI-0050239.P004, AB0010565, KB-146519, TR-018813, EU-0100251, FT-0605518, ST51016017, EN300-37268, 2,4'-DDD, PESTANAL(R), analytical standard, D00420, W-5031, AB00052337-09, AB00052337_10, 000M850, SR-01000075751-1, SR-01000075751-3, SR-01000075751-6, 2,4'-(2,2-dichloroethane-1,1-diyl)bis(chlorobenzene), Z425389592, 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane, 1-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-2-chlorobenzene, Ethane,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-, 1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene #, Mitotane, United States Pharmacopeia (USP) Reference Standard, Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-(8CI), Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- (8CI), 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, analytical standard, o,p'-DDD|||1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane|||Mitotane, 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane for diagnostic uses (cancer investigation), >=98% (HPLC), 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, for diagnostic uses (cancer investigation), >=98% (HPLC)

ID: 1119

InChIKey: JWDYCNIAQWPBHD-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1OCC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4059
synonyms found at PubChem are:
mephenesin, 59-47-2, Decontractyl, Cresoxydiol, Memphenesin, Mephedan, Mephenesine, Anatensin, Cresodiol, Decontractil, Dioloxol, Lissenphan, Lissephen, Mefenesina, Mephelor, Mephesin, Myodetensin, Myodetensine, Atensin, Curaril, Sinan, Kresoxypropandiol, Cresoxypropanediol, Cresossidiolo, Curarythan, Seconesinz, Spartoloxin, Spartoloxyn, Curythan, Daserol, Diloxol, Dioloxal, Findolar, Findolor, Glukresin, Glykresin, Glyotol, Halabar, Kinavosyl, Mephate, Mepherol, Mephosal, Mephson, Mervaldin, Mianesina, Miolisina, Moctynol, Myanesin, Myastenin, Myocuran, Myolysin, Myosera, Myoserol, Myoxane, Nembusen, Nephelor, Noctynol, Oranixon, Prolaxin, Proloxin, Relaxant, Relaxar, Relaxil, Relaxyl, Renarcol, Sansdolor, Saserol, Spasmolyn, Stilalgin, Thioxidil, Thoxidil, Tokerol, Tolansin, Tolbart, Tolhart, Tolofren, Tolosate, Toloxyn, Tolserol, Tolulexin, Tolulox, Tolydrin, Tolynol, Tolyspaz, Torulox, Anxine, Avesyl, Avosyl, Avoxil, Avoxyl, Daserd, Glytol, Mephin, Myanil, Myanol, Myasin, Myolax, Myopan, Myopen, Myopna, Myoten, Myoxyl, Ortol, Prolax, Temian, Tolax, Tolcil, Tolsil, Tolsin, Xeral, Rhex regulans, Walko-Nesin, Cresossipropandiolo, Rhex 'hobeino', o-Cresyl glycerol ether, Glyceryl o-tolyl ether, Ageflex CGE, o-Cresol glyceryl ether, 3-(2-Methylphenoxy)propane-1,2-diol, 1-o-Tolylglycerol ether, 1,2-Propanediol, 3-(2-methylphenoxy)-, Mephenesinum, Mephensin, Myolyseen, 3-(2-Methylphenoxy)-1,2-propanediol, 3-(o-Tolyloxy)propane-1,2-diol, o-Kresol-glycerinaether, BYK-M 1, 3-o-Toloxy-1,2-propanediol, BDH 312, 1-Ortho-tolylglycerol ether, 3-(2-Tolyloxy)-1,2-propanediol, Walconesin, 3-(o-Methylphenoxy)-1,2-propanediol, Mycocuran, MC 2303, RP 3602, SQ 1156, 3-(o-Tolyloxy)-1,2-propanediol, Mefenesina [INN-Spanish], Mephenesine [INN-French], Mephenesinum [INN-Latin], 1,2-Dihydroxy-3-(2-methylphenoxy)propane, o-Cresyl alpha-glyceryl ether, A 1141, alpha-(o-Tolyl)glyceryl ether, o-Kresol-glycerinaether [German], C10H14O3, EINECS 200-427-4, NSC 25234, BRN 2047373, Mefensina, Rex regulans, 1,2-PROPANEDIOL, 3-(o-TOLYLOXY)-, Walco-Nesin, o-Cresyl .alpha.-glyceryl ether, .alpha.-(o-Tolyl)glyceryl ether, NSC25234, alpha,beta-Dihydroxy-gamma-(2-methylphenoxy)propane, component of Tolagesic, NCGC00094908-01, DSSTox_CID_3254, 1, 3-(o-tolyloxy)-, DSSTox_RID_76942, WLN: Q1YQ1OR B1, DSSTox_GSID_23254, 1, 3-(2-methylphenoxy)-, .alpha.,.beta.-Dihydroxy-.gamma.-(2-methylphenoxy)propane, Mephenesin [INN:BAN], SR-05000001772, Mephenesin [INN:BAN:NF], Rhex, CAS-59-47-2, Tolserol (TN), Mephenesin (INN), Prestwick_577, Mephenesin, 98%, 1-(o-tolyl)glycerol, 1-(2-tolyl)glycerol, Spectrum_001402, AC1L1HBM, Prestwick0_000178, Prestwick1_000178, Prestwick2_000178, Prestwick3_000178, Spectrum2_001418, Spectrum3_000908, Spectrum4_001007, Spectrum5_001199, (.+/-.)-Mephenesin, 1-(2-methylphenyl)glycerol, SCHEMBL25448, BSPBio_000075, KBioGR_001473, KBioSS_001882, DivK1c_000076, SPECTRUM1501140, SPBio_001496, SPBio_001996, BPBio1_000083, CHEMBL229128, DTXSID4023254, CHEBI:94398, CTK8G0796, HMS500D18, KBio1_000076, KBio2_001882, KBio2_004450, KBio2_007018, KBio3_001856, KS-00001FBQ, NSC8134, JWDYCNIAQWPBHD-UHFFFAOYSA-N, MolPort-003-666-365, NINDS_000076, HMS1568D17, HMS1921J09, HMS2092F17, HMS2095D17, HMS3712D17, Pharmakon1600-01501140, EBD70999, HY-B1283, NSC-8134, NSC36140, NSC50788, GLYCEROL-1-(O-TOLYL) ETHER, Tox21_111356, CCG-38970, NSC-25234, NSC-36140, NSC-50788, NSC757857, SBB056988, STL430456, AKOS015912866, Tox21_111356_1, API0003293, CS-5340, MCULE-1125347766, NSC-757857, IDI1_000076, NCGC00094908-02, NCGC00094908-03, NCGC00094908-06, BBV-39686544, 3-[(2-methylphenyl)oxy]propane-1,2-diol, SBI-0051654.P002, AB1004849, LS-120750, AB00052216, FT-0628209, ST50407278, W0052, 3-(2-Methylphenoxy)-1,2-propanediol, 98%, D02595, AB00052216_04, SR-05000001772-1, SR-05000001772-2, SR-05000001772-3, BRD-A55469827-001-01-7, I14-49387, 3-(2-Methylphenoxy)-1,2-propanediol; Mephenesin; 3-(o-Tolyloxy)-1,2-propanediol

ID: 1120

InChIKey: JWQRAXTWDYUBFI-UHFFFAOYSA-N
SMILES: C=CCN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957703
synonyms found at PubChem are:
SKF 77434 hydrobromide, 300561-58-4, N-Allyl-(+/-)-SKF-38393 hydrobromide, SKF-77434 hydrobromide, CHEBI:63978, N-Allyl-( inverted exclamation markA)-SKF-38393 hydrobromide, 3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 1-phenyl-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diolhydrobromide, 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide, N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, SR-01000075405, (+/-)-SKF 38393, N-allyl-, hydrobromide, EU-0101143, MLS002153340, CHEMBL1256885, DTXSID5042611, SCHEMBL11288446, CTK8E6902, AOB5002, MolPort-003-959-443, Tox21_501143, AKOS024456732, CCG-222447, LP01143, (+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, NCGC00094408-01, NCGC00261828-01, SMR001230751, NCG-C00094408-01, (y)-SKF 38393, N-allyl-, hydrobromide, RT-014252, (?)-SKF 38393, N-allyl-, hydrobromide, N-Allyl-(A+/-)-SKF-38393 hydrobromide, S-168, J-017750, SR-01000075405-1, SR-01000075405-3, ( inverted exclamation markA)-SKF-77434 hydrobromide, SKF-77434 Hydrobromide (N-Allyl-SKF38393 HBr), ( inverted question mark)-SKF 38393, N-allyl-, hydrobromide, N-Allyl-(+/-)-SKF-38393 hydrobromide, solid, >=98% (HPLC), 1-phenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, 2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol hydrobromide, ( inverted exclamation markA)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, ( inverted question mark)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)

ID: 1121

InChIKey: JWRMHDSINXPDHB-DCPWPRNHSA-N
SMILES: C[C@@H]1CC2C3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5702055
synonyms found at PubChem are:
FLUMETHAZONE PIVALATE, AC1NWAMI, Spectrum_000691, Spectrum2_001265, Spectrum3_000431, Spectrum4_000553, Spectrum5_000708, BSPBio_002042, KBioGR_001245, KBioSS_001171, DivK1c_000304, SPECTRUM1500300, SPBio_001230, SCHEMBL7864998, HMS500P06, KBio1_000304, KBio2_001171, KBio2_003739, KBio2_006307, KBio3_001262, NINDS_000304, HMS1920O12, HMS2091F13, Pharmakon1600-01500300, CCG-39130, NSC757032, NSC-757032, IDI1_000304, NCGC00178849-01, SBI-0051383.P003, AB00051994_02, SR-05000002044, SR-05000002044-1, BRD-A50064262-001-03-9, [2-[(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

ID: 1122

InChIKey: JXIGVERNCHIKAI-UHFFFAOYSA-N
SMILES: C1(=NC=CC=C1)C1C=C(C(=O)O)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 28293307
synonyms found at PubChem are:
716362-11-7, 3-(pyridin-2-yl)-5-isoxazolylcarboxylic acid, SCHEMBL3522095, JXIGVERNCHIKAI-UHFFFAOYSA-N, ZINC19726651, AKOS009284238, MCULE-7796360664, 3-Pyridin-2-ylisoxazole-5-carboxylic acid, 3-(2-pyridinyl)-5-isoxazolecarboxylic acid, FT-0714736, 3-(pyridin-2-yl)-1,2-oxazole-5-carboxylic acid

ID: 1123

InChIKey: JXOHGGNKMLTUBP-HSUXUTPPSA-N
SMILES: C1[C@H]([C@@H]([C@@H](C=C1C(=O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 8742
synonyms found at PubChem are:
shikimic acid, 138-59-0, shikimate, L-Shikimic acid, (-)-Shikimic acid, (3R,4S,5R)-3,4,5-Trihydroxycyclohex-1-enecarboxylic acid, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, CCRIS 7681, HSDB 3537, UNII-29MS2WI2NU, 3alpha,4alpha,5beta-Trihydroxy-1-cyclohexene-1-carboxylic acid, (-)-Shikimate, Bracken fern toxic component, EINECS 205-334-2, NSC 59257, 1-cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R,4S,5R)-, 29MS2WI2NU, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta))-, CHEMBL290345, CHEBI:16119, 3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid, C7H10O5, JXOHGGNKMLTUBP-HSUXUTPPSA-N, [3R-(3alpha,4alpha,5beta)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, (3R,4S,5R)-3,4,5-trihydroxycyclohexene-1-carboxylic acid, (3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid, (4S,3R,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta))- (9CI), SKM, SMR001306700, SR-01000632403, Skikimate, Shicimic Acid, L-Shikimate, 2aay, 4guj, Spectrum_001232, 1we2, 2aa9, SpecPlus_000488, AC1L1RLY, Spectrum2_001508, Spectrum3_001541, Spectrum4_001853, Spectrum5_000386, 1-cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, Shikimic acid, >=99%, bmse000114, EC 205-334-2, SCHEMBL43377, BSPBio_002982, KBioGR_002287, KBioSS_001712, MLS002207031, MLS004256600, DivK1c_006584, SPECTRUM1502256, L-(-)-SHIKIMIC ACID, SPBio_001555, AC1Q59I8, MEGxp0_001939, DTXSID4032039, KBio1_001528, KBio2_001712, KBio2_004280, KBio2_006848, KBio3_002482, KS-00000EYL, MolPort-002-507-279, Shikimic acid, analytical standard, HY-N0130, ZINC3860720, BDBM50281998, CCG-38884, CS-068, CS0026, MFCD00066278, SBB012371, AKOS004119897, AC-8010, AN-8431, EBD2197575, LS-2110, MCULE-9138847690, SDCCGMLS-0066740.P001, SMP1_000326, NCGC00142601-01, NCGC00142601-02, AJ-46044, AS-13905, ST069316, AB0071582, ST2402355, TL8000880, TR-032693, CS-0007856, FT-0080765, N1829, S0038, 3,4,5-Trihydroxycyclohex-1-enecarboxylicacid, C00493, M-2736, 103690-EP2277898A2, 103690-EP2301911A1, 138S590, Q-100148, SR-01000632403-1, SR-01000632403-4, SR-01000632403-5, (-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, B1A53F8A-8664-405D-8370-A9785ADD2D0B, (3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic Acid, 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R,4S,5R)- (9CI), 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R-(3alpha,4alpha,5beta)), Shikimic acid [3R-(3alpha,4alpha,5beta)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid, InChI=1/C7H10O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1,4-6,8-10H,2H2,(H,11,12)/t4-,5-,6-/m1/s

ID: 1124

InChIKey: JXSVIVRDWWRQRT-UYDOISQJSA-N
SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 119034
synonyms found at PubChem are:
Asiatic acid, 464-92-6, Dammarolic acid, UNII-9PA5A687X5, NSC 166063, CHEBI:2873, CHEMBL404313, JXSVIVRDWWRQRT-UYDOISQJSA-N, 9PA5A687X5, Asiantic acid, (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid, Asiatic-acid, HSDB 7662, NSC-166063, 2,3,23-trihydroxyurs-12-en-28-oic acid, (2|A,3|A)-2,3,23-trihydroxyurs-12-en-28-oic acid, Asiatic acid, 97%, AC1Q5QHS, D0LC7K, AC1L3O2W, SCHEMBL3285999, 2alpha,23-Dihydroxyursolic acid, Asiatic acid, analytical standard, MolPort-009-649-413, ZX-AFC002762, ZINC8221271, BDBM50241487, MFCD00238541, AKOS007930256, Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-, CCG-208549, MCULE-1974040943, NCGC00346584-02, AN-45109, Asiatic acid;HSDB 7662;464-92-6, CC-24192, LS-193512, N1356, V1794, C08617, 464A926, C-22852, Q-100489, Asiatic acid, >=98% (HPLC), from Centella asiatica, BRD-K35079116-001-03-3, (2alpha,3beta)-2,3,23-trihydroxyurs-12-en-28-oic acid, Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2alpha,3beta,4alpha)-, Urs-12en-28-oic acid, 2,3,23-trihydroxy-, (2alpha, 3beta, 4alpha)-, (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid, (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-, 0AS

ID: 1125

InChIKey: JXUGSXOSZMZDGF-UHFFFAOYSA-N
SMILES: CC(=O)OC1=C(C2=C(C=C1)C3C4=CC(=C(C(=C4CC3(CO2)O)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708558
synonyms found at PubChem are:
HAEMATOXYLIN PENTAACETATE, KBio2_001070, Spectrum_000590, SpecPlus_000116, AC1O8FDA, Spectrum3_001290, Spectrum4_001596, BSPBio_002899, KBioGR_002212, KBioSS_001070, SPECTRUM240944, DivK1c_006212, CHEMBL1528876, CHEBI:91569, KBio1_001156, KBio2_003638, KBio2_006206, KBio3_002119, CCG-214407, SDCCGMLS-0066555.P001, NCGC00095555-01, NCGC00095555-02, SR-05000002737, SR-05000002737-1, BRD-A18932057-001-01-1, (4,8,9,10-tetraacetyloxy-6a-hydroxy-7,11b-dihydro-6H-indeno[2,1-c]chromen-3-yl) acetate

ID: 1126

InChIKey: JXXCENBLGFBQJM-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CC(CC(=O)O)O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5970
synonyms found at PubChem are:
461-05-2, DL-Carnitine hydrochloride, Carnitine chloride, Monocamin, Carnitine hydrochloride, Carnitine DL- hydrochloride, bicarnesine, (+-)-Carnitine hydrochloride, (+/-)-Carnitine hydrochloride, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, d,l-Carnitine hydrochloride, Vitamin BT Hydrochloride, EINECS 200-305-0, EINECS 207-309-1, Carnitine chloride [JAN], (+/-)-Carnitine chloride, (3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, DL-CARNITINE HCL, Carnitine chloride (JAN), L-Carnitine chloride, C7H15NO3.HCl, ( inverted exclamation markA)-Carnitine (chloride), 56-99-5, 3-Hydroxy-4-(trimethylammonio)butyrate Hydrochloride, L-Carnitine hydrochloride, AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride (1:1), 3-carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride, CARNITINE (dl) HYDROCHLORIDE, Carnitine DL- HCl, NCGC00094816-01, 3-hydroxy-4-(trimethylamino)butanoic acid, chloride, Carnitine L-form hydrochloride, LC-80, EINECS 229-663-6, carnitinhydrochlorid, carnitinium chloride, Vitamin B<v>T, Entomin (TN), 461-05-2[rn], AC1L1LIU, AC1Q1SGT, (+-)-carnitine chloride, l-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, (-)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, (R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride, 1-propanaminium-3-carboxy-2-hydroxy-N,N,N-trimethyl hydroxide, MLS001332614, SCHEMBL357561, SPECTRUM1500624, (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride, 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, (R)-, AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, (-)-, CHEMBL1439419, CTK1F3269, HMS501H12, MolPort-001-795-078, HMS1921K21, HMS2231O13, HMS3370L12, HMS3372B07, HMS3651A18, Pharmakon1600-01500624, HY-B1453, GM8717, MFCD00011904, NSC757390, s2293, SBB003568, AKOS015892785, API0002444, CCG-213758, CS-6453, NSC-757390, VA11215, VC30976, DL-Carnitine hydrochloride, 98% 25g, NCGC00094816-02, CPD000875216, gastric and pancreatic secretion stimulant, LS-17066, LS-17067, LS-17069, SAM002564199, SMR000875216, AB2000550, FT-0625450, ST24046652, ST50983925, D03273, (+/-)-Carnitine hydrochloride, >=98% (TLC), [-]- beta-Hydroxy-gamma-trimethylaminobutyric acid, I04-1030, I04-1123, (2,4-dihydroxy-4-oxobutyl)-trimethylazanium chloride, (+/-)-Carnitine hydrochloride, purum, >=99.0% (AT), beta-Hydroxy-beta-(trimethylammonio)butyrate hydrochloride, beta-Hydroxy-gamma-(trimethylammonio)butyrate hydrochloride, Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, (+-)-, 17360-44-0, 3673-49-2, 51479-53-9, 5852-94-8, 6801-68-9, 68960-71-4, 856319-55-6, dl-carnitine chloride, C-1990, DSSTox_CID_25850, DSSTox_RID_81172, DSSTox_GSID_45850, CAS-461-05-2, C7H16ClNO3, 16224-32-1, DTXSID8045850, CTK8G4044, JXXCENBLGFBQJM-UHFFFAOYSA-N, MolPort-005-932-344, KS-00000G3J, Tox21_111339, GM4580, MFCD00066100, AKOS015899583, Tox21_111339_1, CCG-208519, MCULE-4215013152, TRA0073139, NCGC00263894-02, AK163426, AS-11627, S447, SC-25562, ST51039971, (-)-beta-Hydroxy-gamma-(trimethylammonio)butyrate, I14-058, I14-0058, I14-11235

ID: 1127

InChIKey: JXYWFNAQESKDNC-BTJKTKAUSA-N
SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5284451
synonyms found at PubChem are:
PYRILAMINE MALEATE, Mepyramine maleate, 59-33-6, Anisopyradamine, Histosol, Minihist, Diaminide maleate, Paraminyl maleate, Antihist, Histatex, Histine, Paramal, Pymafed, Pyraninyl, Renstamin, Histan, Pyramal maleate, Stangen maleate, Anthisan maleate, Statomin maleate, Thylogen maleate, Pyra-Maleate, Pyrilamine maleate salt, Neoantergan maleate, Pyranilamine maleate, Pyranisamine maleate, Kriptin maleate, Neo-Antergan maleate, Pyra maleate, Prefrin A, Dorantamin maleate, 2786 R.P. maleate, Enrumay, Histavet-P (veterinary), Mepyramine hydrogen maleinate, Mepyramine maleate salt, Pyma, Histavet-P, Mepiramine maleate, Midol Maximum Strength PMS, Pyrilamine maleate [USAN], UNII-R35D29L3ZA, component of Pyrdex, Pymafed (TN), pyranilamine m aleate, CCRIS 1330, NSC 3604, EINECS 200-422-7, Pyrilamine maleate (USP), component of Endotussin-NN, MLS000069668, R35D29L3ZA, N-Dimethylaminoethyl-N-p-methoxy-alpha-aminopyridine maleate, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine maleate (1:1), N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyridyl)ethylenediamine maleate, N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine maleate, 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), SMR000058495, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine bimaleate, 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine bimaleate, P 5514, Pyridine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-, maleate (1:1), 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1), 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), AH, N,N-dimethyl-N'-{[4-(methyloxy)phenyl]methyl}-N'-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate, PYRILAMINE MALEATE (SEE ALSO PYRILAMINE, CAS 91-84-9), 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine maleate, 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine maleate, N-(Dimethylamino)ethyl-N-(p-methoxy)-.alpha.-aminopyridine maleate, N-(dimethylaminoethyl)-N-(p-methoxyphenyl)-alpha-aminopyridine maleate, N-(p-me thoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine maleate, N-(p-methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine maleate, N-(p-Methoxybenzyl)-N',N'-dimethyl-N-.alpha.-pyridylethylenediamine maleate, N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine but-2-enedioate, N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, 1,2-Ethanediamine, N1-((4-methoxyphenyl)methyl)-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1), CAS-59-33-6, SR-01000000225, Bimaleate, Pyrilamine maleate [USAN:USP], Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1), (Z)-but-2-enedioic acid;N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine, Prestwick_634, Opera_ID_1702, DSSTox_CID_1216, D01NJI, D03GFW, AC1NR4H4, DSSTox_RID_76015, DSSTox_GSID_21216, SCHEMBL27430, MLS001148634, SPECTRUM1500519, CHEMBL1201006, DTXSID4021216, HMS500I17, NSC3604, C16H21N3O.C4H4O4, JXYWFNAQESKDNC-BTJKTKAUSA-N, MolPort-003-666-277, HMS1568J20, HMS1920N10, HMS2092E11, HMS2095J20, HMS2234I23, HMS2234I24, HMS3262B22, HMS3712J20, Pharmakon1600-01500519, HY-B1281, NSC-3604, Tox21_200514, Tox21_500890, BG0398, CCG-39244, LS-251, MFCD00069333, NSC757305, AKOS015950805, LP00890, NSC-757305, NCGC00094209-01, NCGC00094209-02, NCGC00094209-03, NCGC00094209-04, NCGC00094209-05, NCGC00258068-01, NCGC00261575-01, SMR000653462, AB1004850, KB-166333, B6396, CS-0013057, EU-0100890, P2369, ST24031459, D05660, WLN: T6NJ BN1R DO1&2N1&1 &OV1U1VO, SR-01000000225-2, SR-01000000225-4, SR-01000000225-5, SR-01000000225-8, N-(p-Methoxybenzyl)-N,2-ethanediamine, maleic acid salt, 2-((2-(dimethylamino)ethyl )(p-methoxybenzyl)amino)pyridine maleate, 2-[(2-dimethylaminoethyl)(p-methoxybenzyl)amino]pyridine maleate, Mepyramine maleate, European Pharmacopoeia (EP) Reference Standard, 2-[[2-(Dimethylamino)ethyl]( p-methoxybenzyl)amino]pyridine maleate (1:1), Pyrilamine maleate, United States Pharmacopeia (USP) Reference Standard, 1, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-, (Z)-2-butenedioate (1:1), N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine Maleate, N-(p-Methoxybenzyl)-N,N'-dimethyl-N-2-pyridyl-1,2-ethanediamine, maleic acid salt, Pyrilamine maleate, Pharmaceutical Secondary Standard; Certified Reference Material, (Z)-but-2-enedioic acid; N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine, 5572-06-5, Mepyramine maleate salt; N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,N inverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,N inverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-(4-Methoxyphenyl)methyl-N inverted exclamation marka,Ninverted exclamation marka-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt, N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine (2Z)-2-Butenedioate, N1-[(4-Methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-1,2-ethanediamine (2Z)-2-Butenedioate, [2-(dimethylamino)ethyl][(4-methoxyphenyl)methyl]-2-pyridylamine, (2Z)but-2-en edioic acid, SBB057008, AKOS024362796, ST50993906

ID: 1128

InChIKey: JXZCUTPQSYPHMT-UHFFFAOYSA-N
SMILES: CC1=CC(=NC2=CC=CC=C12)NC3=CC=C(C=C3)Br

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "K Du" "O Zegarra-Moran" "AS Verkman" "N Pedemonte" "GL Lukacs" "LJ Galietta"

CID is 768745
synonyms found at PubChem are:
N-(4-bromophenyl)-4-methylquinolin-2-amine, GNF-Pf-268, (4-Bromo-phenyl)-(4-methyl-quinolin-2-yl)-amine, 324526-70-7, AC1LGCGR, BAS 00437701, CBMicro_025025, Oprea1_246881, Oprea1_826009, MLS001077237, SCHEMBL838429, CHEMBL600111, MolPort-001-932-878, HMS2789N21, ZINC248679, CCG-12150, STL383355, AKOS003192686, MCULE-3821665810, SMR000473020, BIM-0025121.P001, N-(4-bromophenyl)-N-(4-methyl-2-quinolyl)amine, SR-01000400434, SR-01000400434-1

ID: 1129

InChIKey: JYGXADMDTFJGBT-VWUMJDOOSA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5754
synonyms found at PubChem are:
hydrocortisone, Cortisol, 50-23-7, Acticort, Cetacort, Hydrocortisyl, Cobadex, Hydrasson, Cortef, Hycort, Hytone, Signef, 17-Hydroxycorticosterone, Optef, Kendall's compound F, Hydrocortone, Cortanal, Cortenema, Corticreme, Cortifan, Cortiment, Cortispray, Cortonema, Dermolate, Efcorbin, Efcortelan, Ficortril, Genacort, Hycortol, Hycortole, Permicort, Proctocort, Tarcortin, Traumaide, Alacort, Cleiton, Cortril, Dihydrocostisone, Hytone lotion, Hidro-Colisona, Hydro-Adreson, Scheroson F, Incortin-H, Reichstein's substance M, Cort-Dome, Domolene-HC, Epiderm H, Esiderm H, Otosone-F, Polcort H, Cortolotion, Cortoxide, Cremesone, Eldercort, Heb-Cort, Maintasone, Delacort, Dioderm, Eldecort, Epicort, Mildison, Penecort, Rectoid, Anflam, Hydrocorticosterone, Hydroxycortisone, H-Cort, Hydro-Colisona, Cortisol alcohol, Incortin-hydrogen, Ala-Scalp, Aeroseb-HC, Barseb HC, Dermocortal, Nutracort, Synacort, Timocort, Evacort, Komed HC, Lacticare-HC, Texacort lotion 25, Ala-Cort, Anti-inflammatory hormone, Hydrocortisone alcohol, Hidrocortisona, Hydrocortisonum, Algicirtis, Aquacort, Cortesal, Cortisolonum, Hidalone, Hytisone, Kyypakkaus, Lactisona, Lubricort, Meusicort, Milliderm, Sanatison, Schericur, Sigmacort, Stiefcorcil, Texacort, Amberin, Cutisol, Dermil, Hydrocortisone base, Uniderm, Foille Insetti, Gyno-Cortisone, Transderma H, Basan-Corti, Clear aid, Cremicort-H, Dome-cort, Neosporin-H Ear, Remederm HC, Aquanil HC, Cortisporin Otico, Derm-Aid, Heb Cort, Scalpicin Capilar, Systral Hydrocort, Prevex HC, Cortisporin, Dermaspray, Efcortelin, Fiocortril, Hydrocortisone free alcohol, Proctofoam, Alphaderm, Colocort, Flexicort, Glycort, Hydracort, Medicort, Otocort, Zenoxone, Drotic, Vytone, 11beta-Hydroxycortisone, Balneol-hc, Stie-cort, Nystaform-HC, Beta-hc, Aeroseb HC, Nogenic HC, CaldeCORT Spray, Hi-cor, Pediotic Suspension, VoSol HC, Idrocortisone, 17alpha-Hydroxycorticosterone, Hydrocortal, Hydroskin, Otalgine, Otobiotic, Protocort, Hysone, Racet, Ef corlin, 11beta-Hydrocortisone, Compound F, Lacticare HC, Compound F (kendall), Idrocortisone [DCIT], Anusol HC, 11-beta-Hydrocortisone, Genacort (lotion), 11-beta-Hydroxycortisone, Epicortisol, Anucort, Chronocort, Cortifair, Hydrocort, Plenadren, Prepcort, Preparation H Hydrocortisone Cream, Hydrocortisonum [INN-Latin], Proctozone HC, Scalp-Cort, Hidrocortisona [INN-Spanish], Rectasol-HC, Anucort-HC, Neo-Cort-Dome, Hydro-RX, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione, HC (HYDROCORTISONE), Otic-Neo-Cort-Dome, 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione, NSC 10483, Corhydron, DuoCort, HC, Hydrocortisone (Cortisol), UNII-WI4X0X7BPJ, HYDROCORTISONE IN ABSORBASE, Neo-Cortef, HC #1, HC #4, [3H]cortisol, Acticort (TN), Colocort (TN), Prestwick_265, Cortef (TN), Hytone (TN), CCRIS 5854, component of Otalgine, Anusol HC (TN), Hydrocortisone [INN:BAN:JAN], 4-Pregnene-11beta,17alpha,21-triol-3,20-dione, component of Lubricort, CHEBI:17650, COR-OTICIN, HSDB 3339, NSC10483, 11.beta.-Hydrocortisone, EINECS 200-020-1, WI4X0X7BPJ, 11beta,17,21-Trihydroxyprogesterone, 11.beta.-Hydroxycortisone, component of Neo-Cort-Dome, ACETASOL HC, ORLEX HC, Terra-cortril, AI3-25006, MLS000069609, (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, 17.alpha.-Hydroxycorticosterone, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, JYGXADMDTFJGBT-VWUMJDOOSA-N, ACETIC ACID W/ HYDROCORTISONE, NSC-10483, Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-, SMR000059022, DSSTox_CID_714, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11-beta)-, HYDROCORTISONE AND ACETIC ACID, H 4001, CALMURID HC, DSSTox_RID_75753, 4-Pregnen-11beta,17alpha,21-triol-3,20-dione, DSSTox_GSID_20714, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, 11beta,17alpha,21-Trihydroxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11b)-, Proctosol-HC, (1S,10S,11S,15S,17S,2R,14R)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-6-en-5-one, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, 80562-38-5, SMR000653523, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-, Cortizol, (11alpha,14beta)-11,17,21-Trihydroxypregn-4-Ene-3,20-Dione, AnusolHC, 3h-cortisol, 11beta-cortisol, CAS-50-23-7, 11-Hydrocortisone, Plenadren (TN), NCGC00022848-06, 11b-Hydrocortisone, Kendalls compound F, Hydrocortisone [USP:INN:BAN:JAN], Drotic (Salt/Mix), 11b-Hydroxycortisone, Otocort (Salt/Mix), Hydrocortisone solution, Otalgine (Salt/Mix), Hydrocortisone, 98%, Alphaderm (Salt/Mix), Hydrocortisone, topical, Otobiotic (Salt/Mix), Reichsteins substance M, 4p6x, Cort-Quin (Salt/Mix), Cortisol, Hydrocortisone, Cortisporin (Salt/Mix), VoSol HC (Salt/Mix), 11a-Hydroxycorticosterone, 17a-Hydroxycorticosterone, Opera_ID_1292, Prestwick0_000447, Prestwick1_000447, Prestwick2_000447, Prestwick3_000447, D0KR5B, Epitope ID:174851, UPCMLD-DP133, EC 200-020-1, AC1L1L2B, SCHEMBL4148, Hydrocortisone, 98% 1g, Hydrocortisone-Water Soluble, Neo-Cort-Dome (Salt/Mix), Lopac0_000594, 11alpha-Hydroxycorticosterone, BSPBio_000494, MLS001148103, MLS002207135, MLS002222189, MLS002548868, SPBio_002433, BPBio1_000544, CHEMBL389621, GTPL2868, Pediotic Suspension (Salt/Mix), DTXSID7020714, UPCMLD-DP133:001, BDBM13775, CTK8F3227, Otic-Neo-Cort-Dome (Salt/Mix), 2v95, Hydrocortisone (JP15/USP/INN), Hydrocortisone (JP17/USP/INN), MolPort-001-794-637, HMS1569I16, HMS2090M04, HMS2096I16, HMS2230B18, HMS2235F17, HMS3259C05, HMS3261H10, HMS3713I16, Hydrocortisone, >=98% (HPLC), Vioform-Hydrocortisone (Salt/Mix), 11b,17,21-Trihydroxyprogesterone, BCP09054, HY-N0583, Tox21_110883, Tox21_200815, Tox21_500594, LMST02030001, MFCD00011654, s1696, SBB012589, ZINC13540519, AKOS001582651, Tox21_110883_1, CCG-204683, CS-2226, Cyclodextrin-encapsulated hydrocortisone, DB00741, LP00594, LS-7439, MCULE-8953627920, NC00456, 11.beta.,17,21-trihydroxyprogesterone, SMP1_000156, NCGC00022848-07, NCGC00022848-09, NCGC00022848-10, NCGC00022848-11, NCGC00022848-12, NCGC00022848-13, NCGC00022848-14, NCGC00022848-15, NCGC00022848-17, NCGC00258369-01, NCGC00261279-01, AC-12902, AJ-64104, AN-24370, AS-11651, BP-20390, CPD000653523, NCI60_000118, SAM002264617, SC-18577, ST069286, 4-Pregnene-11alpha,21-triol 3,20-dione, AB1009452, B1951, EU-0100594, 4-Pregnene-11b,17a,21-triol-3,20-dione, 50H237, 6861-EP2269977A2, 6861-EP2270008A1, 6861-EP2277565A2, 6861-EP2277566A2, 6861-EP2277567A1, 6861-EP2277568A2, 6861-EP2277569A2, 6861-EP2277570A2, 6861-EP2292227A2, 6861-EP2292280A1, 6861-EP2292615A1, 6861-EP2292617A1, 6861-EP2295409A1, 6861-EP2298778A1, 6861-EP2305679A1, 6861-EP2308562A2, 6861-EP2314590A1, 6861-EP2371811A2, 7062-EP2269977A2, 7062-EP2292228A1, 7062-EP2295411A1, 7062-EP2298747A1, 7062-EP2301931A1, 7062-EP2308851A1, 7062-EP2308880A1, 7062-EP2311811A1, 7062-EP2314585A1, C00735, D00088, J10114, U 1851, 92372-EP2280008A2, 92372-EP2289483A1, 92372-EP2305257A1, Hydrocortisone, meets USP testing specifications, Pregn-4-ene-3, 11.beta.,17,21-trihydroxy-, 11?,17?,21-Trihydroxypregn-4-ene-3,20-dione, Hydrocortisone, VETRANAL(TM), analytical standard, SR-01000000139, Q-201211, SR-01000000139-3, 11.beta.,17,21-Trihydroxypregn-4-ene-3,20-dione, BRD-K93568044-001-03-1, BRD-K93568044-001-11-4, BRD-K93568044-001-32-0, Hydrocortisone, BioReagent, suitable for cell culture, 4-Pregnen-11.beta.,17.alpha.,21-triol-3,20-dione, 4-Pregnene-11.beta.,17.alpha.,21-triol-3,20-dione, Pregn-4-ene-3,20-dione, 11.beta.,17,21-trihydroxy-, Z2786051549, (11beta)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione, 11.beta.,17.alpha.,21-Trihydroxy-4-pregnene-3,20-dione, 11.beta.,17.alpha.,21-Trihydroxypregn-4-ene-3,20-dione, B48448A1-24BA-47CA-8D9E-43E5BC949386, Pregn-4-ene-3, 11,17,21-trihydroxy-, (11.beta.)-, 11,17,21-Trihydroxypregn-4-ene-3,20-dione, (11.beta.)-, Hydrocortisone, European Pharmacopoeia (EP) Reference Standard, Hydrocortisone, United States Pharmacopeia (USP) Reference Standard, Hydrocortisone-Water Soluble, BioReagent, suitable for cell culture, (8xi,9xi,11beta,14xi)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Hydrocortisone, gamma-irradiated, powder, BioXtra, suitable for cell culture, 4-(6-chloro-4-oxoquinazolin-3(4H)-yl)-N-(3-methoxyphenyl)piperidine-1-carboxamide, Cortisol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Hydrocortisone for peak identification, European Pharmacopoeia (EP) Reference Standard, Hydrocortisone solution, 50 muM, sterile-filtered, BioXtra, suitable for cell culture, Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material, (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadec-6-en-5-one, 1050676-88-4, 11|A,17|A,21-Trihydroxypregn-4-ene-3,20-dione; 17-Hydroxycorticosterone; 4-Pregnene-11|A,17|A,21-triol-3,20-dione; Cortisol; Kendall inverted exclamation mark s compound F; Reichstein inverted exclamation mark s substance M, 8056-08-4, 8063-42-1

ID: 1130

InChIKey: JYJFNDQBESEHJQ-UHFFFAOYSA-N
SMILES: CC1(C(=O)NC(=O)O1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3081
synonyms found at PubChem are:
dimethadione, 5,5-Dimethyloxazolidine-2,4-dione, 695-53-4, 5,5-Dimethyl-2,4-oxazolidinedione, Dimethadion, Propazone, Eupractone, Dimethyloxazolidinedione, 2,4-Oxazolidinedione, 5,5-dimethyl-, 5,5-Dimethyl-1,3-oxazolidine-2,4-dione, BAX 1400Z, AC 1198, 5,5-Dimethyloxazolidinedione, Dimetadione [DCIT], NSC-30152, Dimethadione [USAN:INN], UNII-ALU9NPM703, Dimetadiona [INN-Spanish], Dimethadionum [INN-Latin], DMO, NSC 30152, Dimethyl-oxazolidine-2,4-dione, BAY 1400Z, EINECS 211-781-4, 5,5-Dwumetylooksazolidyno-2,4-dion, BRN 0113541, ALU9NPM703, AI3-18201, 5,5-Dwumetylooksazolidyno-2,4-dion [Polish], JYJFNDQBESEHJQ-UHFFFAOYSA-N, NSC30152, NCGC00016532-02, CAS-695-53-4, DSSTox_CID_478, 5,5-DIMETHYL OXAZOLIDINE-2,4-DIONE, 5,5-Dimethyloxazolidine-2,4-oxazolidinedione, DSSTox_RID_75614, DSSTox_GSID_20478, Dimetadiona, Dimetadione, Dimethadionum, SR-05000001609, 5,5-Dimethyl-2,4-oxazolidindion, Prestwick_55, 5,4-oxazolidinedione, PubChem8629, 5,5-Dimethyl-2,, Spectrum_000801, Trimethadion, M(nor-), AC1Q6GJV, 5,5-Dimethyl-2,4-oxazolidindion [IUPAC], Prestwick0_000829, Prestwick1_000829, Prestwick2_000829, Prestwick3_000829, Spectrum2_000108, Spectrum3_000398, Spectrum4_000518, Spectrum5_000911, Dimethadione (USAN/INN), ACMC-209o9a, AC1L1F4Q, CHEMBL1099, SCHEMBL34862, BSPBio_000757, BSPBio_002215, KBioGR_001095, KBioSS_001281, DivK1c_000939, SPECTRUM1500253, SPBio_000096, SPBio_002678, BPBio1_000833, DTXSID2020478, BAX-1400Z, CHEBI:94613, CTK8B2187, HMS502O21, KBio1_000939, KBio2_001281, KBio2_003849, KBio2_006417, KBio3_001435, KS-00000JMN, MolPort-003-666-167, NINDS_000939, WLN: T5OVMV EHJ E1 E1, HMS1570F19, HMS1920G22, HMS2091O10, HMS2097F19, HMS3714F19, Pharmakon1600-01500253, ZINC5762010, Tox21_110479, Tox21_200496, ANW-35708, CCG-38926, MFCD00005379, NSC756741, 5, 5-Dimethyloxazolidine-2,4-dione, 5,5'-Dimethyloxazolidine-2,4-dione, 5,5-Dimethyl-oxazolidine-2,4-dione, AKOS015906843, Tox21_110479_1, LS-7339, MCULE-2681916511, NSC-756741, VZ29820, IDI1_000939, 2,4-Oxazolidinedione, 5, 5-dimethyl-, NCGC00016532-01, NCGC00016532-03, NCGC00016532-04, NCGC00016532-07, NCGC00094656-01, NCGC00094656-02, NCGC00258050-01, paragraph signthorn(1/4)xE<<I feminine, AJ-54780, AN-47257, AS-14715, KB-41218, M311, SC-06324, SBI-0051352.P003, DB-055297, ST2418542, TC-124453, TL8004880, A9197, AB00051972, CS-0013093, D0003, FT-0619784, FT-0646768, ST51037235, 5,5-Dimethyl-1,3-oxazolidine-2,4-dione #, 95D534, D-5490, D03838, AB00051972_04, I14-2156, SR-05000001609-1, SR-05000001609-2, BRD-K43687498-001-02-3, F2173-0915, InChI=1/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8, 60254-97-9

ID: 1131

InChIKey: JYNZQZIFQZJCBW-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C=C1)C)NC(=O)CSC2=NN=NN2C3=CC4=C(C=C3)OCO4

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"PW Phuan" "B Yang" "AS Verkman" "GL Lukacs" "JM Knapp" "MJ Kurth" "AB Wood"

CID is 1175670
synonyms found at PubChem are:
ASN 04455937, AC1LM9VO, Oprea1_826725, ZINC932399, AKOS000690345, 2-[1-(1,3-benzodioxol-5-yl)tetrazol-5-yl]sulfanyl-N-(2,5-dimethylphenyl)acetamide

ID: 1132

InChIKey: JYTUSYBCFIZPBE-AMTLMPIISA-N
SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C(=O)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 7314
synonyms found at PubChem are:
LACTOBIONIC ACID, 96-82-2, 4-O-beta-D-Galactopyranosyl-D-gluconic acid, UNII-65R938S4DV, 4-(beta-D-Galactosido)-D-gluconic acid, CHEBI:55481, 65R938S4DV, DSSTox_CID_28787, DSSTox_RID_83056, DSSTox_GSID_48861, Lactobionicacid, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid, CAS-96-82-2, NCGC00016356-01, Prestwick_560, EINECS 202-538-3, 4-(b-d-galactosido)-d-gluconic acid, C12H22O12, Lactobionic acid, purum, Lactobionic acid, 97%, AC1L1OHJ, Prestwick0_000452, Prestwick1_000452, Prestwick2_000452, Prestwick3_000452, AC1Q5R2L, AC1Q77QA, SCHEMBL24870, BSPBio_000524, SPBio_002463, BPBio1_000578, CHEMBL3039602, DTXSID3048861, KS-00000VVK, JYTUSYBCFIZPBE-AMTLMPIISA-N, MolPort-001-793-061, s190, HMS1569K06, HMS2096K06, ZINC4215172, 96-82-2, cGMP, Methyl (R)-(-)-2-Chloromandelate, Tox21_113353, CG-043, GC3782, MFCD00078147, AKOS015896798, AKOS015924795, Tox21_113353_1, API0003109, CCG-214227, EBD2197418, Lactobionic acid, cell impermeant agent, NCGC00179532-01, NCGC00179532-03, 4-O-beta-galactopyranosyl-d-gluconic acid, 5001-51-4 (calcium salt[2:1]), AK209011, AN-42816, AS-16070, KB-78078, SC-97018, 4-O-?-D-Galactopyranosyl-D-gluconic acid, 4-O-|A-D-Galactopyranosyl-D-gluconic acid, AB0018521, FT-0657775, L0005, S-1119, 078L147, I07-0131, D0229170-C0EC-40FC-A777-BF34018EED2A, Lactobionic acid, European Pharmacopoeia (EP) Reference Standard, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)hexanoic acid, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid, 2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid

ID: 1133

InChIKey: JYVXNLLUYHCIIH-ZCFIWIBFSA-N
SMILES: C[C@]1(CCOC(=O)C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6419891
synonyms found at PubChem are:
19115-49-2, (R)-(-)-Mevalonolactone, (-)-Mevalonolactone, UNII-661X270Z3L, (R)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one, Mevalonic-D, L acid lactone, (R)-(-)-3-Hydroxy-3-methyl-5-pentanolide, CHEBI:67849, 661X270Z3L, M-6701, Adeka mevalonolactone, (3R)-Mevalonolactone, Mevalonolactone, (-)-, r-mevalonolactone, (-)-(R)-Mevalonic acid lactone, Prestwick_97, (R)-Mevalolactone, R(-)Mevalonolactone, AC1O4WFW, D-Mevalonic Acid Lactone, Prestwick0_000750, Prestwick1_000750, Prestwick2_000750, SCHEMBL879, R-mevalonolactone, (-)-, SPBio_002679, 2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-, CHEMBL1401520, 2H-Pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-, JYVXNLLUYHCIIH-ZCFIWIBFSA-N, HMS1570E22, ZINC4202723, (4R)-4-hydroxy-4-methyloxan-2-one, AKOS017343730, FCH3612269, (R)-3-hydroxy-3-methyl-5-pentanolide, NCGC00016531-01, AJ-48485, CAS-674-26-0, KB-03244, (R)-3-Hydroxy-3-methyl-|A-valerolactone, DB-044755, FT-0637792, (R)-(-)-Mevalonolactone, >=90.0% (GC), C-01262, I14-86004, UNII-1RJ06DC41B component JYVXNLLUYHCIIH-ZCFIWIBFSA-N

ID: 1134

InChIKey: JZFPYUNJRRFVQU-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4488
synonyms found at PubChem are:
niflumic acid, 4394-00-7, Nifluril, Landruma, Forenol, Actol, Acido niflumico, Nifluminic acid, Acide niflumique, Acidum niflumicum, Acide niflumique [INN-French], Acido niflumico [INN-Spanish], Acidum niflumicum [INN-Latin], Donalgin, Niflumate, 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid, Acide niflumique [French], Acido niflumico [Italian], UP 83, 2-(3-(Trifluoromethyl)-phenyl)aminonicotinic acid, 2-(3-(Trifluoromethyl)anilino)nicotinic acid, 2-[3-(Trifluoromethyl)anilino]nicotinic acid, Niflamol, Niflam, Lopac-N-0630, 2-(3-Trifluoromethylanilino)nicotinic Acid, UNII-4U5MP5IUD8, Niflumic acid [INN:DCF], Niflugel (TN), SC 1332, CCRIS 5740, 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, Niflumic acid (INN), 2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid, 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid, EINECS 224-516-2, 2-(3-Trifluoromethyl-phenylamino)-nicotinic acid, BRN 0489360, 4U5MP5IUD8, MLS000069713, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, NFL, CHEBI:34888, 3-Pyridinecarboxylic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino [French], JZFPYUNJRRFVQU-UHFFFAOYSA-N, 2-[(3-TRIFLUOROMETHYL)PHENYL]AMINO-3-PYRIDINE-CARBOXYLIC ACID, 2-((3-(Trifluoromethyl)phenyl)amino)nicotinic acid, Aza-2 dimethyl-2',3' (tetrazolyl-5)-6 diphenylamino, 2-[alpha,alpha,alpha-trifluoro-m-toluidino]-nicotinic acid, NCGC00015724-10, SMR000058199, CAS-4394-00-7, DSSTox_CID_3368, 2-(3-[Trifluoromethyl]anilino)nicotinic acid, N 0630, DSSTox_RID_76996, 2-(3-(Trifluoromethyl)phenylamino)nicotinic acid, 2-[(3-Trifluoromethylphenyl)amino]nicotinic Acid, DSSTox_GSID_23368, 2-[(3-Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid, Nicotinic acid, 2-(alpha,alpha,alpha-trifluoro-m-toluidino)-, Niflactol, Niflugel, Flunir, Acid, Niflumic, SR-01000000231, 2-[[3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid, NiflumicAcid, ni-flumic acid, Niflumic acid [INN:BAN:DCF], Actol, analgesic, Prestwick_890, PubChem21796, Spectrum_001353, 1td7, ACMC-209jvx, Opera_ID_1746, Prestwick0_000255, Prestwick1_000255, Prestwick2_000255, Prestwick3_000255, Spectrum2_000794, Spectrum3_001485, Spectrum4_000043, Spectrum5_001216, Niflumic acid (Hit 16), D00HGB, AC1L1IA4, CBiol_001828, Lopac0_000845, SCHEMBL24706, BSPBio_000070, BSPBio_001393, BSPBio_003069, KBioGR_000113, KBioGR_000505, KBioSS_000113, KBioSS_001833, 5-22-13-00598 (Beilstein Handbook Reference), KSC587Q8N, MLS001076327, CHEMBL63323, DivK1c_000277, SPECTRUM1502015, SPBio_000928, SPBio_002289, BPBio1_000078, GTPL2439, DTXSID1023368, UPSA Brand 1 of Niflumic Acid, UPSA Brand 2 of Niflumic Acid, BDBM85507, CTK4I7886, HMS500N19, KBio1_000277, KBio2_000113, KBio2_001833, KBio2_002681, KBio2_004401, KBio2_005249, KBio2_006969, KBio3_000225, KBio3_000226, KBio3_002569, MolPort-000-140-647, NINDS_000277, Upsamedica Brand of Niflumic Acid, Bio1_000114, Bio1_000603, Bio1_001092, Bio2_000113, Bio2_000593, HMS1361F15, HMS1568D12, HMS1791F15, HMS1921D12, HMS1989F15, HMS2090D19, HMS2095D12, HMS2234F11, HMS3262J11, HMS3374H01, HMS3402F15, HMS3649A08, HMS3656P14, HMS3712D12, Pharmakon1600-01502015, UP-83, ZINC125031, HY-B0493, KS-00000CB5, NSC_4488, Tox21_110206, Tox21_500845, ANW-30043, BBL003619, CCG-40157, DL-457, MFCD00010569, Nicotinic acid, 2-(.alpha.,.alpha.,.alpha.-trifluoro-m-toluidino)-, NSC758196, s3018, SBB001146, STK803109, UPSA Conseil Brand of Niflumic Acid, AKOS000519590, Tox21_110206_1, AC-2652, CS-2614, DB04552, GS-3202, LP00845, MCULE-3027710274, NSC-758196, RTR-017015, IDI1_000277, IDI1_033863, NCGC00015724-01, NCGC00015724-02, NCGC00015724-03, NCGC00015724-04, NCGC00015724-05, NCGC00015724-06, NCGC00015724-07, NCGC00015724-08, NCGC00015724-09, NCGC00015724-11, NCGC00015724-12, NCGC00015724-13, NCGC00015724-14, NCGC00015724-17, NCGC00023636-03, NCGC00023636-04, NCGC00023636-05, NCGC00023636-06, NCGC00023636-07, NCGC00023636-08, NCGC00023636-09, NCGC00261530-01, AJ-11904, AN-13743, BAS 00821161, BC218927, BR-72979, LS-96639, ST013871, CAS_4394-00-7, SBI-0050821.P003, 2(3'-trifluormethylanilino)-nicotinic acid, AB0012229, AB1004097, 2-(3-(Trifluoromethyl)anilino)nicotinicacid, AB00052255, AM20070143, EU-0100845, FT-0603659, ST24027408, T7852, 2-(A,A,A-Trifluoro-m-toluidino)nicotinic acid, 39690A, C13698, D08275, S00109, AB00052255-17, AB00052255_18, AB00052255_19, 394N007, SR-01000000231-2, SR-01000000231-5, SR-01000000231-6, W-106215, BRD-K98763141-001-04-3, BRD-K98763141-001-06-8, BRD-K98763141-001-17-5, SR-01000000231-11, 2-[3-(Trifluoromethyl)anilino]-3-pyridinecarboxylic acid, Niflumic acid, European Pharmacopoeia (EP) Reference Standard, 2-{[3-(trifluoromethyl)-phenyl]-amino}-3-pyridincarboxylic acid, 2-[3-(Trifluoromethyl)anilino]nicotinic acid; 2-(|A,|A,|A-Trifluoro-m-toluidino)nicotinic acid

ID: 1135

InChIKey: JZNBMCOSOXIZJB-UHFFFAOYSA-N
SMILES: CC(CCCC(C)(C)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10969
synonyms found at PubChem are:
Heptaminol hydrochloride, 543-15-7, Cardiosintol, 6-Amino-2-methyl-2-heptanol hydrochloride, Coreptil, Cortensor, Delmiton, Arcor tropfen, Heptamyl tropfen, Heptylon tropfen, Heptaminol HCl, Heptaminol (hydrochloride), Hept-a-myl tropfen, Heptamyl hydrochloride, 2-Methyl-6-amino-2-heptanol hydrochloride, EA-85, EINECS 208-837-5, 6-amino-2-methylheptan-2-ol hydrochloride, 6-Methyl-2-amino-6-heptanol hydrochloride, R.P. 2831, 2-Heptylamine, 6-hydroxy-6-methyl-, hydrochloride, 2-HEPTANOL, 6-AMINO-2-METHYL-, HYDROCHLORIDE, NCGC00095021-01, 6-Hydroxy-6-methyl-2-heptylamine Hydrochloride, DSSTox_CID_25891, DSSTox_RID_81205, DSSTox_GSID_45891, Corasor, Heptylon, Isoktamil, Izoktamil, Respirin, Eoden, SR-01000872644, Prestwick_257, Heptaminolhydrochlorid, Hept-a-myl (TN), Corasore Hydrochloride, AC1L1WCB, C8H19NO.HCl, CAS-543-15-7, SCHEMBL317122, SPECTRUM1503218, 372-66-7 (Parent), CHEMBL2107282, DTXSID9045891, CTK8J1533, JZNBMCOSOXIZJB-UHFFFAOYSA-N, MolPort-003-666-458, HMS1568C11, HMS1922I21, Pharmakon1600-01503218, HY-B1231, Tox21_111391, CCG-39314, NSC758406, SBB003737, AKOS024348835, Tox21_111391_1, CHM0034847, CS-4878, MCULE-8595786566, NSC-758406, 6-amino-2-methylheptan-2-ol, chloride, NCGC00095021-02, NCGC00178043-05, CC-22425, LS-74420, 6-amino-2-methylheptan-2-ol;hydrochloride, DB-052535, KB-199018, FT-0669129, ST50825179, 6-Hydroxy-6-methyl-2-heptamine Hydrochloride, D08038, 2-Amino-6-hydroxy-6-methylheptane Hydrochloride, 6-AMINO-2-METHYL-2-HEPTANOLHYDROCHLORIDE, 6-Hydroxy-6-methyl-2-aminoheptane Hydrochloride, (5-Hydroxy-1,5-dimethylhexyl)amine Hydrochloride, C-06888, SR-01000872644-1, SR-01000872644-2, Heptaminol hydrochloride, European Pharmacopoeia (EP) Reference Standard, 53572-44-4, AKOS026749772

ID: 1136

InChIKey: JZQKKSLKJUAGIC-NSHDSACASA-N
SMILES: CC(C)NC[C@@H](COC1=CC=CC2=C1C=CN2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 688095
synonyms found at PubChem are:
S(-)-Pindolol, (S)-(-)-pindolol, 26328-11-0, (S)-pindolol, (-)-pindolol, S(?)-Pindolol, CHEMBL117405, CHEBI:48281, (2S)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, (2S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol, (2S)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol, (S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, (2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol, SR-01000075488, espindolol, S-(-)-Pindolol, AC1LELBQ, Tocris-1060, S(-)-Pindolol, solid, SCHEMBL5220, Lopac0_000349, Lopac0_001027, GTPL127, MLS001056774, mt-102, CTK8F2100, ZINC56645, MolPort-003-959-160, HMS2231C09, HMS3261E19, HMS3267E06, Tox21_500349, 2-Propanal, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, (S)-, BDBM50072755, PDSP1_000743, PDSP2_000731, AKOS024456358, API0005632, CCG-204444, LP00349, ACM26328110, NCGC00024973-01, NCGC00024973-02, NCGC00024973-03, NCGC00024973-04, NCGC00024973-05, NCGC00261034-01, SMR000326991, KB-267891, B6575, EU-0100349, EU-0101027, P-152, 328P110, SR-01000597475, J-016382, SR-01000075488-1, SR-01000075488-2, SR-01000597475-1, BRD-K95598440-001-03-6, UNII-BJ4HF6IU1D component JZQKKSLKJUAGIC-NSHDSACASA-N, 2-Propanal,1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-,(S)-, 2-propanol,1-(1h-indol-4-yloxy)-3-[(1-methylethyl)amino]-,(2s)-

ID: 1137

InChIKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=CC2=C1C=CN2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4828
synonyms found at PubChem are:
pindolol, Prinodolol, Visken, Betapindol, 13523-86-9, Carvisken, Durapindol, Pinbetol, Calvisken, Decreten, Pectobloc, Pynastin, Blocklin L, Pindololum, LB-46, Glauco-visken, Glauco-Viskin, Blockin L, LB 46, Prindolol, (+-)-Pindolol, Blocklin-L, DL-Pindolol, Pindololum [INN-Latin], 4-(2-Hydroxy-3-isopropylaminopropoxy)-indole, Blocklin, 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, Carvisken (TN), 4-(3-(Isopropylamino)-2-hydroxypropoxy)indole, Blocklin-L (TN), Visken (TN), CCRIS 9215, HSDB 6539, Pindolol [USAN:INN:BAN:JAN], 1-((1-Methylethyl)amino)-3-(4-indolyloxy)-2-propanol, EINECS 236-867-9, EINECS 244-623-8, 1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol, 2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, 2-Propanol, 1-(4-indolyloxy)-3-(isopropylamino)-, BRN 1536506, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol, CHEBI:8214, DL-LB 46, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol, 2-Propanol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, JZQKKSLKJUAGIC-UHFFFAOYSA-N, P-6820, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, NCGC00015786-11, (1)-1-(1H-Indol-4-yloxy)-3-(isopropylamino)propan-2-ol, DSSTox_CID_3476, P 0778, DSSTox_RID_77043, DSSTox_GSID_23476, DL-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole, 1-((1H-indol-4-yl)oxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol, 1-[1H-INDOL-4-YLOXY]-3-[ISOPROPYLAMINO]-2-PROPANOL, 2-Propanol, 1-(1H-indol-4-yloxy)-3-(1-methylethyl)amino-, 2-Propanol, 1-(indol-4-yloxy)-3-(isopropylamino)-, (+-)-, SMR000059120, SR-01000000027, LB46, (rs)-pindolol, Betapindol (TN), Durapindol (TN), Calvisken (TN), Pectobloc (TN), Prindolol (TN), Decreten (TN), Pinbetol (TN), Pynastin (TN), Prestwick_397, Blocklin L (TN), CAS-13523-86-9, Blockin L (TN), Pindolol [USAN:USP:INN:BAN:JAN], Glauco-Visken (TN), Spectrum_001109, (.+/-.)-Pindolol, Prestwick0_000090, Prestwick1_000090, Prestwick2_000090, Prestwick3_000090, Spectrum2_001285, Spectrum3_000547, Spectrum4_000479, Spectrum5_001266, (R,S)-PINDOLOL, CHEMBL500, D0F2PO, GTPL91, PINDOLOL,(-), AC1L1J1N, AC1Q1QC1, SCHEMBL5219, Lopac0_000955, Oprea1_770884, BSPBio_000020, BSPBio_002193, KBioGR_000958, KBioSS_001589, 5-21-03-00017 (Beilstein Handbook Reference), MLS000069496, MLS002548891, DivK1c_000837, SPECTRUM1500488, Pindolol (JP15/USP/INN), Pindolol (JP17/USP/INN), SPBio_001289, SPBio_001959, BPBio1_000022, DTXSID8023476, CTK8G2432, HMS502J19, KBio1_000837, KBio2_001589, KBio2_004157, KBio2_006725, KBio3_001693, MolPort-001-792-503, NINDS_000837, HMS1568A22, HMS1920H16, HMS2089I21, HMS2091P20, HMS2095A22, HMS3259I07, HMS3262P12, HMS3267K17, HMS3369E14, HMS3712A22, Pharmakon1600-01500488, (+-)-lb46, HY-B0982, Pindolol, >=98% (TLC), powder, Tox21_110221, Tox21_500955, BDBM50019443, BG0392, CCG-39223, MFCD00010530, NSC757276, PDSP1_000771, PDSP1_000772, PDSP2_000759, PDSP2_000760, (+/-)-Pindolol-d7(iso-propyl-d7), AKOS015969756, Tox21_110221_1, API0000920, CS-4473, DB00960, LP00955, MCULE-7764948919, NC00467, NSC-757276, IDI1_000837, NCGC00015786-06, NCGC00015786-07, NCGC00015786-08, NCGC00015786-09, NCGC00015786-10, NCGC00015786-13, NCGC00015786-14, NCGC00015786-16, NCGC00015786-20, NCGC00024925-03, NCGC00024925-04, NCGC00024925-05, NCGC00024925-06, NCGC00024925-07, NCGC00261640-01, AN-18448, CC-33796, CPD000059120, SAM002264631, SC-25688, SBI-0050929.P004, LS-122385, AB00052072, EU-0100955, FT-0630406, ST50319990, Z3376, C07445, D00513, AB00052072-11, AB00052072_12, AB00052072_13, 1-(4-Indolyloxy)-3-(isopropylamino)-2-propanol, 523P869, C-15218, L000006, 3-indol-4-yloxy-1-[(methylethyl)amino]propan-2-ol, SR-01000000027-2, SR-01000000027-4, SR-01000000027-5, SR-01000000027-7, (+-)-4-(2-hydroxy-3-(isopropylamino)propoxy)indole, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol, BRD-A97701745-001-05-3, BRD-A97701745-001-09-5, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol #, Pindolol, European Pharmacopoeia (EP) Reference Standard, [2-hydroxy-3-(1H-indol-4-yloxy)propyl](propan-2-yl)amine, 1-(1h-indol-4-yloxy)-3-((1-methylethyl)amino)-2-propano, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol), Pindolol, United States Pharmacopeia (USP) Reference Standard, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol), 21870-06-4

ID: 1138

InChIKey: JZUFKLXOESDKRF-UHFFFAOYSA-N
SMILES: C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3639
synonyms found at PubChem are:
hydrochlorothiazide, 58-93-5, Hypothiazide, Esidrix, HCTZ, Oretic, Dichlotiazid, Hidrotiazida, Hydrochlorothiazid, Hydrochlorthiazide, Hydrodiuretic, Hydrosaluric, Servithiazid, Aquarills, Aquarius, Dichlotride, Diclotride, Disalunil, Hypothiazid, Idrotiazide, Maschitt, Megadiuril, Newtolide, Thiuretic, Vetidrex, Drenol, Esidrex, Hidril, Hydril, Nefrix, Chlorosulthiadil, Hidrochlortiazid, Hydro-Diuril, Hydro-Aquil, Dihydrochlorothiazide, Jen-Diril, HydroDIURIL, Dihydrochlorothiazid, Dihydrochlorothiazidum, Apresazide, Carozide, Chlorzide, Dichlorosal, Hidroronol, Hydrothide, Hydrozide, Moduretic, Neoflumen, Urodiazin, Bremil, Cidrex, Direma, Dyazide, Fluvin, Ivaugan, Panurin, Ro-hydrazide, Neo-codema, Acuretic, Caplaril, Hydrocot, Microzide, Thlaretic, Timolide, Diaqua, Aquazide H, Lotensin HCT, 3,4-Dihydrochlorothiazide, Aldoril, Hydropres, Thiaretic, Vaseretic, Ziac, Zide, Diu-melusin, Apo-Hydro, Lopressor HCT, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Hydro-D, Hydrochlorothiazidum, Dichlothiazide, Hidrosaluretil, Acesistem, Aldazida, Briazide, Catiazida, Chlorizide, Chlothia, Condiuren, Dihydran, Disothiazid, Diurogen, Dixidrasi, Esoidrina, Hyclosid, Indroclor, Medozide, Mikorten, Modurcen, Natrinax, Novodiurex, Pantemon, Saldiuril, Selozide, Spironazide, Acuilix, Clorana, Didral, Hytrid, Manuril, Mictrin, Nefrol, Roxane, Tandiur, Unazid, Urozide, Dihydrochlorurit, Hidro-Niagrin, Hydro-Saluric, Dihydrochlorurite, Hidroclorotiazida, Raunova Plus, Concor Plus, Aquazide-H, Neo-Flumen, Neo-Minzil, Hydro Par, Hydro-T, Hydrochlorthiazidum, HCT-Isis, Su 5879, Mazide 25 mg, Hydrochlorat, Hydrochlorot, Prinzide, Sectrazide, Hydrochlorothiazide Intensol, Idroclorotiazide, Diu 25 Vigt, Hydrex-semi, Aldactazide 25/25, Aldectazide 50/50, Dihydroxychlorothiazidum, Inderide 80/25, NCI-C55925, Idroclorotiazide [DCIT], component of Cyclex, component of Esimil, Esidrix (TN), Ser-Ap-Es, component of Aldoril, component of Dyazide, component of Caplaril, HCZ, Chlorsulfonamidodihydrobenzothiadiazine dioxide, Dichlorotride, Dicyclotride, Hydrochlorzide, component of Aldactazide, Hydrozide Injection, Veterinary, diclot ride, Ezide, Hidroclorotiazida [INN-Spanish], Hydro-chlor, Hydrochlorothiazidum [INN-Latin], panurin dichloride, UNII-0J48LPH2TH, C7H8ClN3O4S2, Microzide (TN), component of Butizide Prestabs, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, CCRIS 2082, HSDB 3096, Hydrochlorothiazide [INN:BAN:JAN], EINECS 200-403-3, NSC 53477, BRN 0625101, 0J48LPH2TH, 6-Chloro-3,4-dihydro-(2H)-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide, MLS000069619, CHEBI:5778, H.H. 25/25, H.H. 50/50, JZUFKLXOESDKRF-UHFFFAOYSA-N, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, NSC53477, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, HCT, CAS-58-93-5, NCGC00015508-08, SMR000035778, DSSTox_CID_713, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1, 1-dioxide, 6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, H 4759, DSSTox_RID_75752, DSSTox_GSID_20713, AF-614/30832002, Q-201210, 3,4-dihydro-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, SR-01000000119, Hydrokraft, Idrodiuvis, Manschitt, Urirex, HydroPar, 6-chloro-1,1-dioxo-2H,3H,4H-benzo[e]1,2,4-thiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Dichlotride (TN), Hydrodiuril (TN), Prestwick_263, Esidrex (TN), Hydrochloro Thiazide, HydroSaluric (TN), Aquazide H (TN), Hyzaar (Salt/Mix), Oretic (TN), Apo-Hydro (TN), Aldoril (Salt/Mix), MaybridgeCompound 10, Dutoprol (Salt/Mix), Inderide (Salt/Mix), Prinzide (Salt/Mix), adiazine-1,1-dioxide, Accuretic (Salt/Mix), Hydropres (Salt/Mix), Thiazide, hydrochloro-, Hydrochlorothiazide [USP:INN:BAN:JAN], Spectrum_000877, Opera_ID_168, AC1L1GDT, Maybridge1_004336, Prestwick0_000009, Prestwick1_000009, Prestwick2_000009, Prestwick3_000009, Spectrum2_001040, Spectrum3_000456, Spectrum4_000006, Spectrum5_000824, Lopac-H-4759, CHEMBL435, D0U4UQ, Tekturna HCT (Salt/Mix), AC1Q55FM, cid_3639, SCHEMBL9349, Lopac0_000614, Oprea1_357174, BSPBio_000017, BSPBio_002132, KBioGR_000351, KBioSS_001357, KSC492I2H, ARONIS24316, BIDD:GT0153, DivK1c_000289, SPECTRUM1500335, BMCL182567 Compound 6a, SPBio_001259, SPBio_001938, BPBio1_000019, GTPL4836, Hydrochlorothiazide, 98% 5g, Hydrochlorothiazide, crystalline, DTXSID2020713, BDBM13076, component of Dyazide (Salt/Mix), CTK3J2423, HMS500O11, HMS553N04, KBio1_000289, KBio2_001357, KBio2_003925, KBio2_006493, KBio3_001352, KS-00000VPM, BBC/472, component of Caplaril (Salt/Mix), MolPort-000-144-465, NINDS_000289, HMS1568A19, HMS1920D19, HMS2091L05, HMS2095A19, HMS2235I09, HMS3259O17, HMS3261L10, HMS3370P11, HMS3428A05, HMS3655M21, HMS3712A19, Pharmakon1600-01500335, ZINC896569, 6-Chloro-7-sulfamoyl-3, 4-dihy, BCP22001, EBD18905, HY-B0252, JFD00715, ZX-AS004676, ZX-AT004440, Tox21_110165, Tox21_201565, Tox21_300292, Tox21_500614, BG0215, CCG-40240, IMED56428485, LS-243, MFCD00051765, NSC-53477, NSC757059, OR0507, s1708, SBB056984, STK315354, 3,2,4-benzothiadiazine-1,1-dioxide, Hydrochlorothiazide (JP15/USP/INN), Hydrochlorothiazide (JP17/USP/INN), AKOS000121373, Tox21_110165_1, AC-8114, AN-8344, API0002941, CS-2232, DB00999, LP00614, MCULE-6585933943, NC00510, NSC-757059, PS-3162, IDI1_000289, KS-0000477T, WLN: T66 BSWM EM DHJ HG ISZW, NCGC00015508-01, NCGC00015508-02, NCGC00015508-03, NCGC00015508-04, NCGC00015508-05, NCGC00015508-06, NCGC00015508-07, NCGC00015508-09, NCGC00015508-10, NCGC00015508-11, NCGC00015508-12, NCGC00015508-13, NCGC00015508-14, NCGC00015508-16, NCGC00015508-17, NCGC00021906-03, NCGC00021906-04, NCGC00021906-05, NCGC00021906-06, NCGC00021906-07, NCGC00021906-08, NCGC00254017-01, NCGC00259114-01, NCGC00261299-01, BAS 00371709, CJ-04492, CPD000035778, NCI60_004317, SAM002554901, SC-16312, SC-60934, ST033548, component of Butizide Prestabs (Salt/Mix), Hydrochlorothiazide 1.0 mg/ml in Methanol, SBI-0050596.P004, AB1009416, KB-199316, RT-000622, AB00052012, EU-0100614, FT-0082750, FT-0650564, dro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-3,2,4-benzothiadiazine 1,1-dioxide, A19550, C07041, D00340, J10079, AB00052012-15, AB00052012_16, AB00052012_17, BENZENEETHANIMIDAMIDE,3-CHLORO-N-HYDROXY-, 051H765, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi, Hydrochlorothiazide, meets USP testing specifications, I09-0531, SR-01000000119-2, SR-01000000119-4, SR-01000000119-6, BRD-K13078532-001-05-2, Z56347248, 6-Chloro-3,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,2,4-benzothiadiazine 1,1-dioxide, Hydrochlorothiazide, drug standard, 1.0 mg/mL in methanol, 6-chloro-3,4-dihydro-1,1-dioxo-7-sulfamoyl-1,2,4-benzothiadiazine, Hydrochlorothiazide, European Pharmacopoeia (EP) Reference Standard, 3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothiadiazine-1,1-dioxide, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, 6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulphonamide-1,1-dioxide, 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2, 4-benzothiadiazine 1,1-dioxide, 6-chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-7-sulfamoyl-3, 4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-Dioxide, 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, Hydrochlorothiazide, United States Pharmacopeia (USP) Reference Standard, 2H-1,2, 4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1, 1-dioxide, 2H-1,2,4-Benzothiadiazine, 6-chloro-3,4-dihydro-7-sulfamoyl-2, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-,1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, 6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1, 1-dioxide, 7-(Aminosulfonyl)-6-chloro-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-Dioxide, Hydrochlorothiazide for peak identification, European Pharmacopoeia (EP) Reference Standard, Hydrochlorothiazide, Pharmaceutical Secondary Standard; Certified Reference Material, 125727-50-6, 3,4-Dihydro-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide; 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide; 3,4-Dihydrochlorothiazide, 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 8049-49-8

ID: 1139

InChIKey: KAHMEWANVDFFCQ-UHFFFAOYSA-N
SMILES: COC1=C(C(=CC=C1)OC)OCCNCC2COC3=CC=CC=C3O2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957505
synonyms found at PubChem are:
WB 4101 hydrochloride, WB-4101 hydrochloride, WB4101 hydrochloride, 2170-58-3, CHEBI:64094, N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride, 2-(2,6-Dimethoxyphenoxyethyl)aminomethyl-1,4-benzodioxane hydrochloride, N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride, MLS000859914, 2- (2,6-DIMETHOXYPHENOXYETHYL)AMINOMETHYL-1,4-BENZODIOXANE HYDROCHLORIDE (WB 4101), N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanaminium chloride, SR-01000075254, SMR000326775, (2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)[2-(2,6-dimethoxyphenoxy)ethyl]ammonium chloride, EU-0100335, SCHEMBL989002, SPECTRUM1503647, CHEMBL556001, DTXSID2042565, CTK8G3780, MolPort-003-666-495, Tox21_500335, BN0543, CCG-39353, AKOS024458707, LP00335, NCGC00093775-01, NCGC00093775-02, NCGC00093775-03, NCGC00261020-01, LS-33979, KB-220648, WB-4101 hydrochloride, analytical standard, D 0411, J-014246, SR-01000075254-1, SR-01000075254-3

ID: 1140

InChIKey: KBAUFVUYFNWQFM-UHFFFAOYSA-N
SMILES: CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11224
synonyms found at PubChem are:
Doxylamine succinate, 562-10-7, Decapryn, Doxylamine (succinate), Evigoa D, A-H Injection, Decapryn Succinate, Doxylamine succinate salt, Unisom, Alsadorm, Gittalun, Mereprine, Sedaplus, Doxy-sleep-aid, Doxylamine succinate (1:1), Hoggar N, Decapryn succinate (1:1), Doxylamine hydrogen succinate, CCRIS 4811, EINECS 209-228-7, NSC 74772, Doxylamine succinate [USP], AI3-23993, MLS000028417, 2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate (1:1), CHEBI:82461, Dimethylaminoethoxy-methyl-benzyl-pyridine succinate, 2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate, SMR000058436, Decapryn (TN), DSSTox_CID_552, Phenyl2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether succinate, 2-(alpha-(2-Dimethylaminoethoxy)-alpha-methylbenzyl)pyridine succinate, Doxylamine-d5 Succinate, 2-(alpha(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine succinate (1:1), Doxylamine succinate (USP), alpha-(2-Dimethylaminoethoxy)-alpha-methyl-alpha-phenyl-2-picoline acid succinate, Butanedioic acid, compd. with N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine (1:1), Butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1), DSSTox_RID_75656, DSSTox_GSID_20552, C21H28N2O5, N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine succinate, N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine succinate, N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethenamine succinate, Topcare sleep aid, Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, butanedioate (1:1), Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1), SR-01000003036, EQUALINE SLEEP AID, Doxylamine succinate liquid, Decarpyn succinate (1:1), Safetussin, N,N-dimethyl-2-[1-phenyl-1-pyridin-2-ylethoxy]ethanamine succinate, butanedioic acid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, C17H22N2O.C4H6O4, NCGC00017028-02, CAS-562-10-7, Prestwick_887, Opera_ID_566, doxylamine; succinic acid, AC1L1WW1, AC1Q5VR4, Pyridine, succinate (1:1), MLS000758288, MLS001076141, MLS001424137, MLS002222274, SCHEMBL160443, SPECTRUM1500267, CHEMBL1200392, DTXSID7020552, HMS502K03, MolPort-003-666-172, HMS1568E15, HMS1920K04, HMS2051F14, HMS2091B09, HMS2095E15, HMS2231G05, HMS3261E17, HMS3370K04, HMS3393F14, HMS3652H19, HMS3712E15, Pharmakon1600-01500267, BCP24067, HY-A0069, NSC74772, Tox21_113515, Tox21_202078, Tox21_302861, Tox21_500348, BG0679, CCG-38929, MFCD00056168, NSC-74772, NSC756752, s4240, AKOS025310916, Tox21_113515_1, AC-4487, API0002494, CCG-101033, CS-3232, LP00348, LS-1380, NC00283, NSC-756752, NCGC00016140-02, NCGC00016140-03, NCGC00016140-04, NCGC00021147-11, NCGC00089789-03, NCGC00093785-01, NCGC00093785-02, NCGC00093785-03, NCGC00256517-01, NCGC00259627-01, NCGC00261033-01, AN-11902, AS-13661, BC678008, CPD000058436, Q835, SAM001247030, ACM1216840946, AB0017830, KB-295989, EU-0100348, FT-0082833, FT-0625595, WLN: T6NJ BX1&R&O2N1&1 &OV2VO, C19414, D 3775, D-9200, D02327, J10070, SR-01000003036-2, SR-01000003036-6, SR-01000003036-9, (Dimethylamino)ethoxy-methyl-benzyl-pyridine succinate, F2173-1155, [[[(2-Dimethylamino)ethoxy]phenyl]methyl]-2-picoline succinate, 2-[a-[2-(Dimethylamino)ethoxy]-a-methylbenzyl]pyridine succinate, Doxylamine Hydrogen Succinate 1.0 mg/ml in Methanol (as free base), butanedioic acid,N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, butanedioic acid; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, Doxylamine succinate, United States Pharmacopeia (USP) Reference Standard, n,n-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine butanedioate, N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine; succinic acid, Phenyl2-pyridylmethyl-(.beta.-N,N-dimethylamino)ethyl ether succinate, 2-[[.alpha.-(2-Dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine succinate, Butanedioic acid,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1), Doxylamine for system suitability, European Pharmacopoeia (EP) Reference Standard, Doxylamine hydrogen succinate, European Pharmacopoeia (EP) Reference Standard, Doxylamine Succinate, Pharmaceutical Secondary Standard; Certified Reference Material, 121367-03-1, Succinic acid, compd. with 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine (1:1), Succinic acid, compd. with 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine (1:1) (8CI), Succinic acid, compd. with 2-[.alpha.-[2-(dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine (1:1), dimethyl[2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl]amine, butanedioic acid, SBB057413, AKOS024366248, MCULE-7394342520, ST50999670

ID: 1141

InChIKey: KBDSLGBFQAGHBE-MSGMIQHVSA-N
SMILES: C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 179651
synonyms found at PubChem are:
Limonin, 1180-71-8, Dictamnolactone, Obaculactone, Citrolimonin, Evodin, Limonine, 7,16-Dioxo-7,16-dideoxylimondiol, Limoni, Limonoic acid, di-delta-lactone, UNII-L0F260866S, NSC 36508, Limonoate D-ring-lactone, CHEBI:16226, L0F260866S, Limonoic acid 3,19:16,17 dilactone, limonoic acid 3,19:16,17-dilactone, DSSTox_CID_25985, DSSTox_RID_81273, DSSTox_GSID_45985, limonoic acid di-delta-lactone, Evodia fruit, (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)-12-(3-furyl)-6,6,8a,12a-tetramethyldecahydro-3H-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione, (4aS,6aR,8aR,8bR,9aS,12S,12aS,14aR,14bR)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-1H,3H-oxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione, CAS-1180-71-8, AI3-37932, 3-furyl(tetramethyl)[?]trione, NSC36508, CCRIS 4047, NCGC00095714-01, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-, Spectrum2_001728, Spectrum3_001012, Spectrum4_001140, Spectrum5_000935, AC1L45NQ, Limonin, analytical standard, BSPBio_002763, KBioGR_001659, Limonoic acid di-del.-lactone, SCHEMBL320315, SPECTRUM1800018, SPBio_001776, CHEMBL517449, DTXSID8045985, ACon1_001996, KBio3_001983, Limonoic acid di-.delta.-lactone, KBDSLGBFQAGHBE-MSGMIQHVSA-N, MolPort-001-742-490, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-, 11H,13H-Oxireno(d)pyrano(4',3':3,3a)isobenzofuro(5,4-f)(2)benzopyran-4,6,13(2H,5aH)-trione, 8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-, (2aR-(2aalpha,4abeta,4bR,5aalpha,8alpha,8aalpha,10aalpha,10bR*,14aalpha))-, 1392-24-1, ZINC4096134, Tox21_111513, BDBM50418089, CCG-38796, MFCD00075922, AKOS015965307, Tox21_111513_1, AC-8045, CS-1237, HBL0000164, SDCCGMLS-0066837.P001, NCGC00178483-01, NCGC00178483-02, NCGC00178483-04, NCGC00178483-05, NCGC00263659-01, AS-15249, CC-29957, HY-17411, O622, SC-13316, AB0016554, L0258, Limonin, from citrus seeds, >90% (HPLC), N1349, S2319, C03514, W-5068, 180L718, C-22706, Q-100083, BRD-K05906022-001-03-6, BRD-K05906022-001-05-1, (4aS,6aR,8aR,8bR,9aS,12S,12aS,14aR,14bR)-12-(Furan-3-yl)-6,6,8a,12a-tetramethyldecahydrooxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(1H,6H,8aH)-trione

ID: 1142

InChIKey: KBOPZPXVLCULAV-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1N)C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4075
synonyms found at PubChem are:
5-Aminosalicylic acid, Mesalazine, mesalamine, 5-Amino-2-hydroxybenzoic acid, 89-57-6, Pentasa, Claversal, Asacol, Canasa, Salofalk, Rowasa, 5-ASA, m-Aminosalicylic acid, Mesasal, Lialda, Fisalamine, Lixacol, Apriso, Benzoic acid, 5-amino-2-hydroxy-, p-Aminosalicylsaeure, Asacolitin, Mesalazina, Mesalazinum, sfRowasa, 5-amino-2-hydroxy-benzoic acid, Asacol HD, 5-Aminosalicylate, Mesalazinum [Latin], Pentacol, 5-Amino Salicylic Acid, 3-carboxy-4-hydroxyaniline, Mesalamine [USAN], Mesalazina [Spanish], p-Aminosalicylsaeure [German], 2-Hydroxy-5-aminobenzoic acid, Mesavancol, Mesacol, Mesavance, Mezavant, Iialda, Mesalazine MMX, SALICYLIC ACID, 5-AMINO-, Mezavant XL, UNII-4Q81I59GXC, NSC 38877, Mesalamine (USP), Pentasa (TN), Salofalk Granu-Stix, Apriso (TN), Asacol (TN), Canasa (TN), Lialda (TN), Rowasa (TN), 5-AS, CCRIS 7334, Mesalazine (JAN/INN), EINECS 201-919-1, BRN 2090421, AI3-15564, MLS001424012, 4Q81I59GXC, CHEBI:6775, 5-Aminosalicylic Acid, Purified, AJG-501, MAX-002, SPD-476, SPD-480, KBOPZPXVLCULAV-UHFFFAOYSA-N, mesalamine (USAN), Mesalamine HCl, MD-0901, CAS-89-57-6, NCGC00016344-03, SMR000145728, Z-206, DSSTox_CID_4506, DSSTox_RID_77435, DSSTox_GSID_24506, Asacolon, Ascolitin, Delzicol, Fivasa, 5 Aminosalicylate, 5-Aminosalicylicacid, m Aminosalicylic Acid, 5 Aminosalicylic Acid, Novo 5 ASA, Novo-5 ASA, meta Aminosalicylic Acid, meta-Aminosalicylic Acid, SR-01000763486, Hydrochloride, Mesalamine, Mesalamine [USAN:USP], Mesalamine Monosodium Salt, Monosodium Salt, Mesalamine, mesalsal, Salozinal, Asalit, Ipocol, HSDB 7512, minosalicylic acid, SPD 476, Mesalamine (TN), Delzicol (TN), Salofalk (TN), Sfrowasa (TN), Mesalazine [INN], Mesalazina[Spanish], Masacol (TN), Iialda (TN), Ipocal (TN), Mesalamine (Lialda), Novo5 ASA, 5-Aminosalicyclic acid, Meta-AminosalicylicAcid, 5-amino-salicylic acid, PubChem17623, Mesalamine|||Mesalazine, ACMC-1BKFR, Byk Brand of Mesalamine, AC1L1HCS, Falk Brand of Mesalamine, Prestwick0_001069, Prestwick1_001069, Prestwick2_001069, Prestwick3_001069, Axcan Brand of Mesalamine, WLN: ZR DQ CVQ, CHEMBL704, D0C4YC, Solvay Brand of Mesalamine, EC 201-919-1, Allphar Brand of Mesalamine, Antigen Brand of Mesalamine, cid_4075, Farmasa Brand of Mesalamine, Ferring Brand of Mesalamine, Merckle Brand of Mesalamine, Norgine Brand of Mesalamine, Celltech Brand of Mesalamine, Provalis Brand of Mesalamine, Oprea1_847633, SCHEMBL31297, 3amino-6-hydroxybenzoic acid, 5-amino-2-hydroxybenzoicacid, BSPBio_001058, KBioGR_002425, KBioSS_002431, 4-14-00-02058 (Beilstein Handbook Reference), KSC448C0L, MLS000758287, Novopharm Brand of Mesalamine, 5-Aminosalicylic acid, 95%, 5-Aminosalicylic acid, tablet, ARONIS23914, BIDD:GT0811, 3-amino-6-hydroxybenzoic acid, SmithKline Brand of Mesalamine, SPBio_002969, Yamanouchi Brand of Mesalamine, AC1Q51L9, BPBio1_001164, GTPL2700, ZINC1688, 5-Amino 2-hydroxy benzoic acid, DTXSID5024506, 5-Aminosalicylic acid, >=99%, 6291-36-7 (hydrochloride), BDBM60918, CTK3E8105, KBio2_002425, KBio2_004993, KBio2_007561, KBio3_002904, Salicylic acid, 5-amino-(8CI), cMAP_000045, MolPort-001-641-024, HMS1571E20, HMS2051M21, HMS2090I09, HMS2098E20, HMS3393M21, HMS3649K15, HMS3651M15, HMS3715E20, Pharmakon1600-01505993, Henning Berlin Brand of Mesalamine, BCP05326, GlaxoSmithKline Brand of Mesalamine, KS-00000CC5, KS-000048PQ, NSC38877, Schering Plough Brand of Mesalamine, Schering-Plough Brand of Mesalamine, Tox21_110384, Tox21_201610, Tox21_303125, 5-?Aminosalicylic Acid (Mesalazine), 5-Amino-2-hydroxybenzoic acid 97%, AN-874, ANW-39326, BBL013046, FC1035, MFCD00007877, NSC-38877, NSC759301, s1681, SBB052617, STK301678, Procter & Gamble Brand of Mesalamine, Sanofi Synthelabo Brand of Mesalamine, AKOS000118959, Tox21_110384_1, AC-2764, BCP9000175, CCG-100829, CS-2219, DB00244, HS-0100, LS-1894, LS11426, MCULE-5752745805, NC00079, NSC-759301, RP21708, RTR-032941, TRA0073805, NCGC00016344-01, NCGC00016344-02, NCGC00016344-04, NCGC00016344-05, NCGC00016344-07, NCGC00090934-01, NCGC00090934-02, NCGC00257142-01, NCGC00259159-01, 35589-28-7 (mono-hydrochloride salt), AJ-08068, BP-13074, BR-72925, CPD000145728, HY-15027, SAM001247020, SC-15695, 5-Aminosalicylic acid, analytical standard, AB1001921, KB-196569, KB-196728, ST2411704, ST4109571, TR-032941, A0317, AB00374979, AM20060091, FT-0619950, 1764-EP2272825A2, 1764-EP2275420A1, D00377, M-7246, 24215-EP2289518A1, 24215-EP2295053A1, 24215-EP2295409A1, 24215-EP2314574A1, 24215-EP2314590A1, 90701-EP2371811A2, AB00374979-09, AB00374979-10, AB00374979_11, AB00374979_12, 5-amino-2-hydroxybenzoic acid,5-Aminosalicylic acid, I06-0488, Q-201355, SR-01000763486-3, SR-01000763486-4, SR-01000763486-9, Z57127471, F1918-0003, 5-Amino-2-hydroxybenzoic acid; 5-AS; Mesalamine; 5-ASA, A3613/0153179, Mesalazine, European Pharmacopoeia (EP) Reference Standard, Mesalamine, United States Pharmacopeia (USP) Reference Standard, 5-aminosalicylic acid, Mesalazine, Asacol, Pentasa, Canasa, Mesalamine, Mesalamine, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11, Mesalazine for system suitability, European Pharmacopoeia (EP) Reference Standard, 61513-32-4, SCHEMBL18038934

ID: 1143

InChIKey: KBUKUKLNLPJWCO-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCOC2=CC=CC=C2)S(=O)(=O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"N Liu" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile" "J Liao" "C Pavel" "SM Anjos"

CID is 2747481
synonyms found at PubChem are:
1-(benzenesulfonyl)-4-(2-phenoxyethyl)piperazine, MixCom1_000005, AC1MCMVR, AC1Q6VJV, Maybridge1_000005, Oprea1_668388, MolPort-001-841-346, ZINC19924752, AKOS008690847, MCULE-4730077666, Z46248350, 876686-44-1

ID: 1144

InChIKey: KBXIJIPYZKPDRU-UHFFFAOYSA-N
SMILES: C(C(=O)O)ON.C(C(=O)O)ON.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2723609
synonyms found at PubChem are:
2921-14-4, Carboxymethoxylamine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, Aminooxyacetic acid hemihydrochloride, 2-(Aminooxy)acetic acid hydrochloride (2:1), UNII-5G5QI2GN7A, 2-(Aminooxy)acetic acid hydrochloride(2:1), Acetic acid, (aminooxy)-, hydrochloride (2:1), Acetic acid, 2-(aminooxy)-, hydrochloride (2:1), 5G5QI2GN7A, Carboxymethoxyamine hemihydrochloride, (Aminooxy)acetic acid hemihydrochloride, Aminooxyacetic acid hemichloride, bis(2-(aminooxy)acetic acid) hydrochloride, EINECS 220-862-3, NSC 40358, NSC 50782, NSC 56446, AI3-52279, Acetic acid, (aminooxy)-, hemihydrochloride, O-Carboxymethylhydroxylamine hemihydrochloride, ACETIC ACID, 2-AMINOOXY-, HYDROCHLORIDE (2:1), Bis((aminooxy)acetic) acid hydrochloride, EU-0100007, Carboxymethoxylamine hemiHCl, AC1MC37X, SCHEMBL1091588, CHEMBL1492415, CTK8B7764, KBXIJIPYZKPDRU-UHFFFAOYSA-N, MolPort-006-114-801, 2-aminooxyacetic Acid Hydrochloride, KS-00000Y2F, Tox21_500007, ANW-58462, bis(aminooxyacetic acid) hydrochloride, carboxymethoxyl amine hemihydrochloride, (Carboxymethoxy)amine hemihydrochloride, AKOS016002992, 2-Aminooxyacetic acid hemihydrochloride, CC-1596, CCG-221311, CS-8158, LP00007, RTR-012749, NCGC00093533-01, NCGC00260692-01, 2-(Aminooxy)acetic acid hemihydrochloride, 2-(Aminooxy)acetic acid hydrochloride (2, HY-107994, FT-0623483, Hydroxylamine-O-acetic acid hemihydrochloride, ST24027601, O-carboxymethyl hydroxylamine hemihydrochloride, A 4508, O-(carboxymethyl) hydroxylamine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, 98%, Aminooxyacetic acid; (Carboxymethoxy)amine hemihydrochloride, O-(Carboxymethyl)hydroxylamine hemihydrochloride, purum, >=97.0% (AT)

ID: 1145

InChIKey: KCBZSNWCUJBMHF-UHFFFAOYSA-F
SMILES: C1=CC(=C(C=C1S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C2=CC(=CC(=C2)NC(=O)NC3=CC(=CC(=C3)C(=O)NC4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC5=C(C=C(C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC6=C(C=C(C=C6)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4469
synonyms found at PubChem are:
NCGC00025139-01, Tocris-1391, GTPL4267, MolPort-003-983-648, HMS3267D22, 1,3-disodium 4-{[3-({[3,5-bis({2,4-bis[(sodiooxy)sulfonyl]phenyl}carbamoyl)phenyl]carbamoyl}amino)-5-({2,4-bis[(sodiooxy)sulfonyl]phenyl}carbamoyl)benzene]amido}benzene-1,3-disulfonate, NF449 octasodium salt, NF 449, octasodium 4-[[3-[[3,5-bis[(2,4-disulfonatophenyl)carbamoyl]phenyl]carbamoylamino]-5-[(2,4-disulfonatophenyl)carbamoyl]benzoyl]amino]benzene-1,3-disulfonate, 389142-38-5, 4,4',4'',4'''-[Carbonylbis-(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium, 627034-85-9, Lopac-N-4784, D0D9AA, AC1L1I8J, AC1O1BH3, CHEMBL1253351, AKOS024456567, CCG-208812, NCGC00016178-01, NCGC00016178-02, NCGC00094191-01, EU-0100867, N 4784, 4,4',4",4"'-[Carbonyl-bis[imino-5,1,3-benzenetriyl bis-(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid), 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt, NF-499, B6716

ID: 1146

InChIKey: KCECBJRHWSOTMR-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C(CO)O)O.COC1=C(C=CC(=C1)C(CO)O)O.C1CNCCN1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2723890
synonyms found at PubChem are:
MHPG piperazine, 67423-45-4, 4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt, MOPEG piperazine, 3-Methoxy-4-hydroxy-phenylglycol piperazine, DL-4-Hydroxy-3-methoxyphenylglycol piperazine salt, MHPG piperazine;, MOPEG piperazine;, EINECS 266-689-7, MOPEG piperidinium salt, AC1MC3TL, CHEMBL1593209, CTK8F6025, HMS3261B08, DL-4-Hydroxy-3-methoxyphenylethyleneglycol - piperazine (2:1), Tox21_500563, MFCD00065957, CCG-204653, LP00563, NCGC00093948-01, NCGC00261248-01, 4-Hydroxy-3-methoxyphenylglycol piperazine;, EU-0100563, FT-0641125, KS-00001835, 4-Hydroxy-3-methoxyphenylglycol hemipiperazine salt, 1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol; piperazine, 4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt, >=98.0% (HPLC), 1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol compound with piperazine (2:1)

ID: 1147

InChIKey: KCISFICQVCMQEX-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=COC3=C(C2=O)C(=CC(=C3OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3279840
synonyms found at PubChem are:
ISOTECTORIGENIN TRIMETHYL ETHER, 8-Hydroxygenistein-5,7,8,4'-tetramethyl ether, 5,7,8-trimethoxy-3-(4-methoxyphenyl)chromen-4-one, 13539-23-6, SPBio_000396, Spectrum_000765, SpecPlus_000147, AC1MM3MW, Spectrum2_000578, Spectrum3_000699, Spectrum4_001618, Spectrum5_000375, BSPBio_002457, KBioGR_001995, KBioSS_001245, SPECTRUM201341, DivK1c_006243, CHEMBL1481076, KBio1_001187, KBio2_001245, KBio2_003813, KBio2_006381, KBio3_001677, CHEBI:108594, CCG-38503, SDCCGMLS-0066384.P001, NCGC00095505-01, NCGC00095505-02, NCGC00178643-01, BRD-K10505056-001-02-0, 5,7,8-trimethoxy-3-(4-methoxyphenyl)-4H-chromen-4-one

ID: 1148

InChIKey: KCOOTJRKKIDHTM-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1C(=O)O)O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6710680
synonyms found at PubChem are:
HAEMATOMMIC ACID, 3-formyl-2,4-dihydroxy-6-methylbenzoic acid, Hamatommsaure, KBio2_006900, Spectrum_001284, 3-Formylorsellinic acid, Spectrum2_001922, Spectrum3_001118, Spectrum4_001959, Spectrum5_000699, AC1O8JW9, BSPBio_002856, KBioGR_002401, KBioSS_001764, SPECTRUM1400131, SPBio_001923, CHEMBL1315277, SCHEMBL13495709, KBio2_001764, KBio2_004332, KBio3_002076, CCG-38489, AKOS022645221, SDCCGMLS-0066839.P001, NCGC00095742-01, NCGC00095742-02, acide formyl-3-dihydroxy-2,4-methyl-6-benzoique, SR-05000002430, SR-05000002430-1, BRD-K03463894-001-02-7, 2-Hydroxy-3-(hydroxymethylene)-6-methyl-4-oxo-3,4-dihydrobenzoic acid, 479-25-4

ID: 1149

InChIKey: KCURWTAZOZXKSJ-JBMRGDGGSA-N
SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6252
synonyms found at PubChem are:
CYTARABINE HYDROCHLORIDE, Cytosine arabinoside hydrochloride, 69-74-9, Cytarabine HCl, Ara-C hydrochloride, 1-beta-D-Arabinofuranosylcytosine hydrochloride, Cytosar hydrochloride, Spongocytidine hydrochloride, Arabitin hydrochloride, Aracytin hydrochloride, Cylocide, Cytarabin hydrochloride, Arabinosylcytosine hydrochloride, Aracytidine hydrochloride, Cytarabine (hydrochloride), CCRIS 4774, Arabinosyl cytosine hydrochloride, Cytarabine hydrochloride [USAN], U-19920A, UNII-33K3DB6591, EINECS 200-713-9, Cytosine-1-beta-D-arabinofuranoside hydrochloride, C9H13N3O5.HCl, AI3-52344, MLS000028466, 1beta-D-Arabinofuranosylcytosine hydrochloride, 1beta-D-Arabinofuranosylcytosine monohydrochloride, 1-beta-D-Arabinofuranosylcytosine monohydrochloride, Cytosine, 1-beta-D-arabinofuranosyl-, hydrochloride, Cytosine, 1-beta-D-arabinofuranosyl-, monhydrochloride, Cytosine, 1beta-D-arabinofuranosyl-, monohydrochloride, 33K3DB6591, Cytosine beta-D-arabinofuranoside hydrochloride, SMR000058432, Arabinofuranosylcytosine hydrochloride, 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-, monohydrochloride, AC 1075, U 19920A, Cytarabine hydrochloride (USAN), Cytosine, 1-beta-D-arabinofuranosyl-, monohydrochloride, NSC 63878, 4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride, Alexan hydrochloride, SR-01000075773, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one hydrochloride, Cytosine Arabinoside HCl, Opera_ID_1542, DSSTox_CID_4891, AC1L1M4C, AC1Q3EJ1, Arabinocytidine hydrochloride, DSSTox_RID_77571, DSSTox_GSID_24891, SCHEMBL67288, MLS001148147, MLS002207299, 147-94-4 (Parent), CHEMBL1256472, DTXSID5024891, KCURWTAZOZXKSJ-JBMRGDGGSA-N, Tox21_300488, Tox21_500316, HY-13605A, MFCD00012839, 1-Beta-D-Arabinofuranosylcytosine HCl, AKOS015896936, AKOS015960559, AKOS015995277, CCG-221620, CS-2178, LP00316, LS-1589, RP29823, CAS-69-74-9, NCGC00093762-01, NCGC00254321-01, NCGC00261001-01, 29363-79-9, AC-11705, AN-41923, K172, KB-11375, 69-74-9 (HCL), 1-b-D-Arabinofuranosylcytosine hydrochloride, DB-025611, Cytosine-ss-D-arabinofuranoside hydrochloride, EU-0100316, FT-0083569, ST24046404, 1-beta-D-Arabinofuranosylcytosinehydrochloride, 1-(b-D-Arabinofuranosyl)cytosine hydrochloride, A-8763, C 6645, D03637, 069C749, C-49658, 1-(beta-d-arabino-furanosyl)-cytosine hydrochloride, SR-01000075773-1, Cytosine beta-D-arabinofuranoside hydrochloride, crystalline, CYTARABINE HYDROCHLORIDE (SEEALSO CYTARABINE 147-94-4), 2(1H)-Pyrimidinone,4-amino-1-b-D-arabinofuranosyl-,hydrochloride (1:1), Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Ara-C hydrochloride, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one hydrochloride, 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one hydrochloride

ID: 1150

InChIKey: KCXVZYZYPLLWCC-UHFFFAOYSA-N
SMILES: C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

biological descriptors:

CFTR relevance: Fe3+ chelator, CFTR activator

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment unknown

reference list:

"G Wang"

CID is 6049
synonyms found at PubChem are:
EDTA, Edetic acid, Ethylenediaminetetraacetic acid, 60-00-4, Edathamil, Versene, Endrate, Havidote, Titriplex, EDTA acid, Sequestrol, Cheelox, Sequestric acid, Warkeelate acid, Gluma cleanser, Sequestrene aa, Komplexon ii, Quastal Special, Tetrine acid, Versene acid, Metaquest A, Trilon bw, Complexon II, Hamp-ene acid, Titriplex II, Cheelox BF acid, Trilon BS, Celon A, Chelest 3A, Questex 4H, Celon ATH, Chemcolox 340, Versenate, Acide edetique, Acido edetico, Acidum edeticum, Universne acid, Calcium disodium versenate, Vinkeil 100, Dissolvine E, Nullapon B acid, Nullapon bf acid, Perma kleer 50 acid, Nervanaid B acid, Clewat TAA, (Ethylenedinitrilo)tetraacetic acid, EDTA (chelating agent), Ethylenedinitrilotetraacetic acid, Caswell No. 438, Disodium EDTA, Chelaton 3, ICRF 185, Acide ethylenediaminetetracetique, Cheladrate, SEQ 100, Edetate calcium, Ethylenebisiminodiacetic acid, YD 30, Acide edetique [INN-French], Acido edetico [INN-Spanish], Acidum edeticum [INN-Latin], CCRIS 946, Edetate, ETHYLENEDIAMINE TETRAACETIC ACID, HSDB 809, Ethylenediamine-N,N,N',N'-tetraacetic acid, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, UNII-9G34HU7RV0, CaEDTA, Acetic acid, (ethylenedinitrilo)tetra-, Calcium disodium edetate, EPA Pesticide Chemical Code 039101, Edta disodium, Disodium edetate, Disodium versene, Endrate disodium, Kyselina ethylendiamintetraoctova, Sodium versenate, Edetic acid disodium salt, Ethylenediaminetetraacetate, Kyselina ethylendiamintetraoctova [Czech], Acide ethylenediaminetetracetique [French], Metaquest B, Kiresuto B, Chelaplex III, Complexon III, Diso-Tate, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, AI3-17181, Chelaton III, Potassium EDTA, Versene NA, Triplex III, Disodium versenate, Edathamil disodium, Trilon BD, Versene Na2, C10H16N2O8, Disodium sequestrene, Disodium tetracemate, EDTA disodium salt, EINECS 200-449-4, F 1 (complexon), EDTA, ion(4-), CHEMBL858, Sequestrene sodium 2, Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid, BRN 1716295, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, Edetate calcium disodium, 9G34HU7RV0, Perma Kleer Di Crystals, Calcium Disodium Edetate (JAN), Calcium disodium versenate (TN), CHEBI:42191, KCXVZYZYPLLWCC-UHFFFAOYSA-N, 4-04-00-02449 (Beilstein Handbook Reference), Ethylenediaminetetraacetic acid disodium salt, Edetate calcium disodium (USP), Sequestrene Na2, Trilon B, Selekton B2, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid, Disodium ethylenediaminetetraacetate, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, (ethylenedinitrilo)tetraacetic acid, ion(4-), Perma kleer 50 crystals disodium salt, Disodium (ethylenedinitrilo)tetraacetate, Disodium ethylenediaminetetraacetic acid, SODIUM ETHYLENEDIAMINETETRAACETATE, CBC 50152966, DR-16133, Ethylenediaminetetraacetate, disodium salt, Disodium diacid ethylenediaminetetraacetate, J-610078, D'E.d.t.a. disodique, Disodium (ethylenedinitrilo)tetraacetic acid, EDTA, 500 mM Solution, pH 8.0, ULTROL® Grade, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, Disodium dihydrogen ethylenediaminetetraacetate, Tetracemate, Edetates, Disodium dihydrogen(ethylenedinitrilo)tetraacetate, 139-33-3, Calcium Tetacine, Distannous EDTA, Chromium EDTA, Stannous EDTA, Gallium EDTA, Copper EDTA, NSC2760, 470462-56-7, Disodium Calcitetracemate, N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], NCGC00159485-02, ETHYLENEDIAMINETETRAACETIC ACID, ACS, Edetic acid [INN:BAN], Ethylene Dinitrilotetraacetate, disodium-edta, Edetic acid [INN:BAN:NF], Ethylenebis(iminodiacetic acid), (Ethylenedinitrilo)tetraacetic acid, disodium salt, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid, Techrun DO, H4edta, Zonon AO, EDTA, free acid, EDTA, free base, Versene acid (TN), Disodium Ethylene Dinitrilotetraacetate, Edetic Acid, Disodium, Magnesium Salt, Acroma DH 700, Spectrum_001018, ACMC-209mhe, AC1L1LOX, Edetic acid (NF/INN), 10058-42-1, Spectrum2_000003, Spectrum3_000412, Spectrum4_000531, Spectrum5_000955, Edetic acid [BAN:INN], DSSTox_CID_2977, D00KEP, D01DTJ, EC 200-449-4, DSSTox_RID_76814, DSSTox_GSID_22977, ethylenediaminetetracetic acid, BSPBio_001964, Diaminoethane-tetraacetic acid, Diaminoethanetetra-acetic acid, Ethylenediamineteraacetic Acid, KBioGR_001161, KBioSS_001498, KSC352S1H, MLS001249457, BIDD:ER0565, DivK1c_000777, ethylenediamine tetracetic acid, SPBio_000005, ethylenediamine-tetraacetic acid, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-, DTXSID6022977, ethylene diamine tetraacetic acid, ethylene-diamine tetraacetic acid, (ethylenedinitrilo)tetraaceticacid, CTK2F2913, KBio1_000777, KBio2_001498, KBio2_004066, KBio2_006634, KBio3_001184, BIE0729, EBD3431, Ethylenedinitrilo-tetraacetic acid, (Ethylenedintrilo)tetraacetic acid, MolPort-001-788-408, NINDS_000777, ZX-AFC000762, 7379-27-3 (potassium salt), 24669-13-4 (chromium salt), KS-00000G4L, 7379-28-4 (hydrochloride salt), Tox21_202736, 2001-94-7 (di-potassium salt), ANW-33408, BDBM50330325, GE4011, MFCD00003541, SBB008807, STK386291, ZINC19364242, 139-33-3 (di-hydrochloride salt), AKOS001574475, Glycine, (N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, labeled with carbon-14, (ethane-1,2-diyldinitrilo)tetraacetate, CHM0029903, DB00974, MCULE-1868494404, RL04264, RTR-020771, ZC00001, 53404-51-6 (mono-potassium salt), CAS-60-00-4, IDI1_000777, NCGC00159485-03, NCGC00159485-04, NCGC00260284-01, 10058-42-1 (iron(3+) salt), 17421-79-3 (mono-hydrochloride salt), 688-55-1, AC-10615, ACM470462567, AJ-72922, AN-19025, AN-23308, AN-41801, LS-12098, SC-18421, SMR000058776, ST072179, SBI-0051360.P003, (ethane-1,2-diyldinitrilo)tetraacetic acid, KB-296903, TR-020771, 76353-66-7 (calcium,hydrochloride salt), B7197, E0084, Ethylenediaminetetraacetic acid, 2Na (EDTA), Ethylenediaminetetraacetic acid, 99% 500g, Ethylenediaminetetraacetic acid, LR, >=98%, FT-0083197, FT-0626319, ST24030413, C00284, D00052, Ethylenediaminetetraacetic acid, p.a., 98.0%, AB00053468_03, Ethylenediaminetetraacetic acid solution, 0.02 N, Ethylenediaminetetraacetic acid, >=98.0% (KT), 6381-92-6 (di-hydrochloride salt, di-hydrate), A832566, N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, SR-01000883946, I04-0860, SR-01000883946-1, 37C3C5E7-D921-445F-82D6-FEBF1AE5AEF5, I14-19418, Z2688689169, Ethylenediaminetetraacetic acid, BioUltra, >=99.0% (KT), Ethylenediaminetetraacetic acid, 99.995% trace metals basis, Ethylenediaminetetraacetic acid, SAJ special grade, >=99.0%, Ethylenediaminetetraacetic acid, Vetec(TM) reagent grade, 98%, [{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]acetic acid, 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Edetic acid, United States Pharmacopeia (USP) Reference Standard, Edetic acid; EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil, Ethylenediaminetetraacetic acid, ACS reagent, 99.4-100.6%, powder, Ethylenediaminetetraacetic acid, purified grade, >=98.5%, powder, 2,2'',2'''',2''''''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Ethylenediaminetetraacetic acid, BioUltra, anhydrous, >=99% (titration), Glycine, N,N'-1, {2-ethanediylbis[N-(carboxymethyl)-,} disodium salt, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid(EDTA), 2-[2-[bis(2-hydroxy-2-oxoethyl)amino]ethyl-(2-hydroxy-2-oxoethyl)amino]ethanoic acid, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, Redi-Dri(TM), >=98%, 13440-78-3, 161122-33-4, 20539-27-9, 26627-46-3, 30485-87-1, 30485-88-2, 30485-90-6, 32757-10-1, 402925-67-1, 675141-16-9, 94108-75-5, Ethylenediamine-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetraacetic Acid-13C4 (|A-labels), Ethylenediaminetetraacetic acid solution, 0.02% in DPBS (0.5 mM), sterile-filtered, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid solution, BioUltra, for molecular biology, pH 8.0, ~0.5 M in H2O, Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, powder, Redi-Dri(TM), ACS reagent, 99.4-100.6%, InChI=1/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20, AC1NR0SS, 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)azaniumyl]ethyl]azaniumyl]acetate

ID: 1151

InChIKey: KDFBGNBTTMPNIG-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)CCN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 67652
synonyms found at PubChem are:
Tryptamine hydrochloride, 343-94-2, 3-(2-Aminoethyl)indole hydrochloride, 2-(1H-indol-3-yl)ethanamine hydrochloride, 1H-Indole-3-ethanamine, monohydrochloride, Tryptamine monohydrochloride, TRYPTAMINEHYDROCHLORIDE, CCRIS 4419, UNII-2942LD1Q06, Indole-3-ethylamine hydrochloride, 3-(2-Aminoethyl)-1H-indole monohydrochloride, beta-Indole-ethylamine hydrochloride, EINECS 206-446-4, beta-3-Indolylethylamine hydrochloride, NSC 522258, 2-(Indol-3-yl)ethylamine hydrochloride, beta-Indolaethylamin-chlorhydrat [German], AI3-24258, 1H-Indole-3-ethanamine, hydrochloride (1:1), 2-(3-Indolyl)ethylamine hydrochloride, 2942LD1Q06, Indole, 3-(2-aminoethyl)-, monohydrochloride, T-8150, 2-indol-3-ylethylamine, chloride, 61-54-1 (Parent), tryptamine-hcl, beta-Indolaethylamin-chlorhydrat, SR-01000075589, Tryptamine HCl, Tryptamine, HCl, PubChem9449, 2-(1h-indol-3-yl)ethanaminhydrochlorid, Tryptamine hydrochloride salt, SCHEMBL274183, ACMC-209i75, Tryptamine hydrochloride, 99%, AC1L280T, AC1Q38V6, Jsp006237, CHEMBL1255796, DTXSID9059836, CTK3J1227, KS-00000WGJ, KDFBGNBTTMPNIG-UHFFFAOYSA-N, MolPort-003-928-498, .beta.-Indolaethylamin-chlorhydrat, Tox21_500061, WLN: T56 BMJ D2Z & GH, ANW-27855, MFCD00012682, NSC522258, RW3341, SBB000359, AKOS004910399, API0004536, CCG-221365, LP00061, NSC-522258, QC-2231, RTR-030642, .beta.-Indole-ethylamine, hydrochloride, 3-(beta-aminoethyl)-indole hydrochloride, NCGC00093575-01, NCGC00260746-01, .beta.-3-Indolylethylamine, hydrochloride, AC-25536, AN-23410, AS-11527, LS-82296, LS-82297, 2-(1H-Indol-3-yl)ethanaminehydrochloride, 2-(1H-indol-3-yl)ethanamine,hydrochloride, AB0010248, AX8156046, DB-048617, KB-177063, TR-030642, 2-(1H-Indol-3-yl);ethanamine hydrochloride, A0300, EU-0100061, FT-0631988, ST24027440, ST50308497, 2-(1H-indol-3-yl)-ethylamine hydrochloride salt, C-49605, I10-0178, SR-01000075589-1, MolPort-000-736-788, MCULE-2705006421

ID: 1152

InChIKey: KDUWXMIHHIVXER-UHFFFAOYSA-N
SMILES: CCC(=O)C1=CC=CC=C1O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 69133
synonyms found at PubChem are:
2'-Hydroxypropiophenone, 610-99-1, 1-(2-hydroxyphenyl)propan-1-one, 2-Propionylphenol, 1-Propanone, 1-(2-hydroxyphenyl)-, o-Hydroxypropiophenone, o-Propiophenol, Propiophenone, 2'-hydroxy-, UNII-ZGH9CA1BFI, ZGH9CA1BFI, ortho-Hydroxypropiophenone, KDUWXMIHHIVXER-UHFFFAOYSA-N, 1-Propanone,1-(2-hydroxyphenyl)-, 2 -Hydroxypropiophenone, NSC3785, EINECS 210-244-1, 2-(Propionyl)phenol, PubChem21422, ACMC-1AYBX, AI3-11684, 2'-hydroxy-propiophenone, 2/'-Hydroxypropiophenone, 2\'-Hydroxypropiophenone, Propiophenone, o-hydroxy-, EC 210-244-1, AC1L2B6V, AC1Q5FM4, 2-Hydroxyphenyl ethyl ketone, Ethyl 2-Hydroxyphenyl Ketone, SCHEMBL111675, 2'-Hydroxypropiophenone, 97%, CHEMBL151116, CTK5B2704, DTXSID90209868, MolPort-001-783-849, 1-(2-Hydroxyphenyl)-1-propanone, ZINC391093, KS-00000UX5, NSC-3785, ANW-33683, BBL011846, MFCD00002220, SBB063301, STL163409, 1-(2-Hydroxyphenyl)-1-propanone #, AKOS000121339, MCULE-6236011886, RP21360, AC-10642, AN-46456, AS-12054, SC-76192, TC-122428, FT-0612634, ST50824215, 2 inverted exclamation marka-Hydroxypropiophenone, I01-1175, W-105197, F1908-0078, 1-(2-HYDROXYPHENYL)-PROPANONE (2-HYDROXY-PROPIOPHENONE), InChI=1/C9H10O2/c1-2-8(10)7-5-3-4-6-9(7)11/h3-6,11H,2H2,1H

ID: 1153

InChIKey: KFEAUMZKRNJEDU-BTJKTKAUSA-N
SMILES: CC1=C(C2=C(N1)C=CC(=C2)O)CCN.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9836150
synonyms found at PubChem are:
2-Methylserotonin maleate, 2-Methylserotonin maleate salt, 78263-91-9, EU-0100813, SCHEMBL1320833, CHEMBL1491258, AOB5681, MolPort-035-944-445, HMS3262D07, Tox21_500813, AKOS025142140, CCG-222117, LP00813, NCGC00094146-01, NCGC00261498-01, LS-194105, 2-Methylserotonin maleate, >=95% (HPLC), M-109, SR-01000075557-1

ID: 1154

InChIKey: KFJZVXKPPQIYCG-UHFFFAOYSA-N
SMILES: CCN(CC)CCCCCCCCOC(=O)C1=CC(=C(C(=C1)OC)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 150613
synonyms found at PubChem are:
CCRIS 7561, EINECS 258-574-5, 3,4,5-Trimethoxybenzoic acid, 8-(diethylamino)octyl ester, hydrochloride, Diethyl(8-(3,4,5-trimethoxybenzoyloxy)octyl)ammonium chloride, 3,4,5,-Trimethoxybenzoic acid 8-(diethylamino)octyl ester hydrochloride, AC1L44OR, 57818-92-5 (Parent), LS-182391, diethyl-[8-(3,4,5-trimethoxybenzoyl)oxyoctyl]azanium chloride, 53464-72-5, TMB-8 hydrochloride, 8-(Diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride, TMB-8, Hydrochloride, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate, IN1056, 8-(N,N-Diethylamino)-octyl-3,4,5-trimethoxybenzoate, HCl, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride, 3,4,5-Trimethoxybenzoic Acid 8-(Diethylamino)octyl Ester, Hydrochloride, 3,4,5-Trimethoxybenzoic Acid 8-Diethylamino-n-octyl Ester Hydrochloride, TMB 8 hydrochloride, AC1OCEPW, MLS002153307, ACMC-1B069, SCHEMBL5682553, CHEMBL1256666, CTK8C5800, REGID_for_CID_6917843, Tox21_500022, NSC379318, AKOS015888376, CCG-221326, LP00022, MCULE-2208552656, NSC-379318, NCGC00093545-01, NCGC00260707-01, SMR001230723, TC-168061, EU-0100022, FT-0614162, TMB-8 inverted exclamation mark currency HCl, C-49531, SR-01000075348, SR-01000075348-1, I01-10369, 3,4,5-TRIMETHOXYBENZOIC ACID 8-(DIETHYLAMINO) OCTYL ESTER, 8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate hydrochloride, 97%, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride

ID: 1155

InChIKey: KFVSLSTULZVNPG-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 31620
synonyms found at PubChem are:
Terbutaline sulphate, Bricanyl Turbuhaler, Terbutaline sulfate, EINECS 245-386-3, 1-(3,5-Dihydroxyphenyl)-2-tert-butylaminoethanol sulphate, (+-)-alpha-((tert-Butylamino)methyl)-3,5-dihydroxybenzyl alcohol sulfate (2:1) (salt), 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, sulfate (2:1) (salt), BENZYL ALCOHOL, alpha-((tert-BUTYLAMINO)METHYL)-3,5-DIHYDROXY-, SULFATE (2:1), AC1L1LZE, AC1Q22KP, Terbutaline sulfate [USAN:JAN], KFVSLSTULZVNPG-UHFFFAOYSA-N, 23031-25-6 (Parent), Terbutaline sulfate [USAN:USP:JAN], LS-42744, tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium sulfate, 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol sulfate(2:1), 98225-49-1, 23031-32-5, TERBUTALINE HEMISULFATE, Terbutaline hemisulfate salt, 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, Brethine (TN), DSSTox_CID_25437, DSSTox_RID_80878, DSSTox_GSID_45437, 2-t-Butylamino-1-[3,5-dihydroxyphenyl]ethanol, 5-(2-(tert-butylamino)-1-hydroxyethyl)benzene-1,3-diol hemisulfate, Terbutalin sulfate, 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol;sulfuric acid, Prestwick_598, Terbutaline(sulfate), Terbutaline (sulfate), 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol; sulfuric acid, bis(5-(2-(tert-butylamino)-1-hydroxyethyl)benzene-1,3-diol) sulfate, Terbutaline sulfuric acid, AC1L9AZM, NCGC00016772-01, CAS-23031-32-5, SCHEMBL26462, CHEBI:9450, sulfuric acid; bis(terbutaline), CHEMBL1315867, DTXSID3045437, CTK8G3346, C24H40N2O10S, MolPort-003-959-699, Terbutaline sulfate (JP17/USP), HMS1569O03, HMS2096O03, HMS3263B13, HMS3713O03, BCP09034, KS-00001F8N, Tox21_110602, Tox21_501126, MFCD00079584, AKOS015909692, Tox21_110602_1, API0005421, CCG-220391, CCG-222430, LP01126, NCGC00016010-09, NCGC00094394-01, NCGC00261811-01, EU-0101126, FT-0674863, V0238, D00688, T 2528, 031T325, SR-01000872654, SR-01000872654-1, I14-31834, F2173-0944, Terbutaline sulfate, British Pharmacopoeia (BP) Reference Standard, Terbutaline sulfate, European Pharmacopoeia (EP) Reference Standard, Terbutaline sulfate, United States Pharmacopeia (USP) Reference Standard

ID: 1156

InChIKey: KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11065
synonyms found at PubChem are:
Amitriptyline hydrochloride, 549-18-8, Amitriptyline HCl, Annoyltin, Tryptizol, Domical, Elavil hydrochloride, Lentizol, Saroten, Amavil, Ami-Anelun, Amineurin, Anapsique, Daprimen, Elatrolet, Maxivalet, Miketorin, Mitaptyline, Rantoron, Sarotena, Syneudon, Trepiline, Triptizol, Tryptine, Trytomer, Vanatrip, Yamanouchi, Amilit, Amiplin, Amiprin, Amitid, Amitrip, Amyline, Amyzol, Belpax, Elatrol, Enafon, Etrafon, Etravil, Kyliran, Larozyl, Levate, Pinsanu, Pinsaun, Teperin, Triavil, Tridep, Tripta, Trynol, Damilen hydrochloride, Endep, Amitriptyline chloride, Saroten Retard, Tryptizol retard, Tryptacap hydrochloride, Apo-Amitriptyline, ADT-Zimaia, Oasil-M, Novoprotect, Novotriptyn, Nornaln, Proheptadien monohydrochloride, sk-Amitriptyline chloride, CCRIS 7092, UNII-26LUD4JO9K, Amitriptyline (hydrochloride), EINECS 208-964-6, Amitryptiline hydrochloride, NIH 10794, NSC 104210, 26LUD4JO9K, Annolytin, MLS000028437, component of Etrafon, component of Triavil, CPD000058368, SMR000058368, Amitryptyline hydrochloride, Elavil (TN), 5-(3-Dimethylaminopropylidene)dibenzo(a,d)(1,4)cycloheptadiene hydrochloride, C20H24ClN, DSSTox_CID_13187, DSSTox_RID_79055, DSSTox_GSID_33187, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine hydrochloride, W-105596, 50-48-6 (Parent), 1-propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, NSC169910, WLN: L C676 BY&T&J BU3N1&1 &GH, SR-01000003046, NCGC00015095-09, CAS-549-18-8, Amilent, Amicen, Euplit, Uxen, 5-(3-Dimethylaminopropylidene)dibenzo[a,4]cycloheptadiene hydrochloride, 5-[3-(Dimethylamino)propylidene]dibenzo[a,4]cycloheptadiene hydrochloride, 1-Propanamine,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride, 5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadiene hydrochloride, 5H-Dibenzo[a,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo[a,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-,hydrochloride, Amitriptyline hydrochloride [JAN], Prestwick_20, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1), 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1), 3-(10,11-dihydro-5h-dibenzo[a,d]cycloheptene-5-ylidene)-n,n-dimethyl-1-propanamine hydrochloride, 3-(5,6-dihydrodibenzo[2,1-b:1',2'-e][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride, DRG-0169, Amitriptyline hydrochloride [USP:JAN], PubChem21398, Opera_ID_618, Nortriptyline Impurity F, AC1L1WJE, Amitryptylline hydrochloride, AC1Q38XC, SCHEMBL41079, MLS001055393, MLS001074176, MLS002222152, SPECTRUM1500117, REGID_for_CID_11065, CHEBI:2667, CHEMBL1200964, DTXSID9033187, HY-B0527A, Amitriptyline Hydrochloride ,(S), Amitriptyline hydrochloride, 99%, KFYRPLNVJVHZGT-UHFFFAOYSA-N, MolPort-003-666-120, ZX-AFC003121, HMS1568O09, HMS1920C13, Pharmakon1600-01500117, 549-18-8(hcl), KS-00000FN4, Tox21_113122, Tox21_201278, Tox21_303612, Tox21_500112, BG0033, BI3855, CCG-38919, MFCD00012537, NSC104210, NSC755869, s3183, AKOS015994716, Tox21_113122_1, API0001458, CS-2751, KS-1291, LP00112, NC00497, NSC-104210, NSC-169910, NSC-755869, Amitriptyline hydrochloride (JP17/USP), Amitriptyline;Amitriptyline hydrochloride, NCGC00015095-15, NCGC00024433-03, NCGC00024433-05, NCGC00093609-01, NCGC00093609-02, NCGC00093609-03, NCGC00093609-04, NCGC00093609-05, NCGC00257393-01, NCGC00258830-01, NCGC00260797-01, AK162589, AN-23652, H905, KB-47353, LS-60749, SAM002554886, AB0013348, AX8114039, A0908, EU-0100112, FT-0662108, ST24045948, A 8404, D00809, J10484, Amitriptyline hydrochloride, >=98% (TLC), powder, SR-01000003046-2, SR-01000003046-6, 5-(3-(Dimethylamino)propylidene) dibenzosuberane HCl, F0001-1443, Amitriptyline Hydrochloride 1.0 mg/ml in Methanol (as free base), Amitriptyline hydrochloride, drug standard, 1.0 mg/mL in methanol, Amitriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Amitriptyline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Amitriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine hydrochloride, 3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride, 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-,hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (8CI), 5H-Dibenzo[a,d]cycloheptene-Delta(sup5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride, 5H-Dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (6CI,8CI), 8058-15-9, dimethyl({3-[(2Z)-tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine hydrochloride, dimethyl({3-[(2Z)-tricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]propyl})amine hydrochloride, AC1LCWFY, AKOS015917367, I14-9588, (3-(5,6-dihydrodibenzo[b,f][7]annulen-11-ylidene)propyl)dimethylamine, chlorid e, MolPort-000-696-255, SBB057420, AKOS024366256, MCULE-6119641097, ST50999679

ID: 1157

InChIKey: KGMMGVIYOHGOKQ-APTPAJQOSA-N
SMILES: CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9931141
synonyms found at PubChem are:
(-)-trans-(1S,2S)-U-50488 hydrochloride, CHEMBL593781, 114528-79-9, SR-01000075483, SR-01000597740, 133162-85-3, trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride, MLS000862195, SCHEMBL7115846, AOB4833, MolPort-003-959-847, Tox21_501266, AKOS024458435, CCG-222570, LP01266, NCGC00094503-01, NCGC00261951-01, SMR000326958, NCG-C00094503-01, LS-191065, (-)-Trans-(1S,2S)-U-50488 HCl, EU-0101266, U-111, ()-trans-(1S,2S)-U-50488 hydrochloride, SR-01000075483-1, SR-01000075483-2, SR-01000597740-1, SR-01000597740-2, SR-01000597740-3, trans-(1S,2S)-3,4-Dichloro-N-methyl-N-(2-[1-pyrollidinyl]cyclohexyl)benzeneacetamide hydrochloride

ID: 1158

InChIKey: KGMMGVIYOHGOKQ-JAXOOIEVSA-N
SMILES: CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6918162
synonyms found at PubChem are:
(+)-U-50488 hydrochloride, U50488 Hydrochloride, (+/-)-U-50488 hydrochloride, (+)-trans-(1R,2R)-U-50488 hydrochloride, 114528-81-3, U-50488 hydrochloride, KGMMGVIYOHGOKQ-JAXOOIEVSA-N, AC1OCF3F, 107902-84-1, C19H26Cl2N2O.HCl, CHEMBL1256834, SCHEMBL10386320, SYN5230, MolPort-003-959-846, 67198-17-8, AKOS024458305, NCGC00094496-01, LS-28506, NCG-C00094496-01, LS-191064, (+)-Trans-(1R,2R0-U-50488 HCl, EU-0101256, U-110, 114528-81-3 (HCl), 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide hydrochloride, trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride, trans-(1R,2R)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide hydrochloride

ID: 1159

InChIKey: KGPAYJZAMGEDIQ-UHFFFAOYSA-N
SMILES: CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 15548
synonyms found at PubChem are:
Laudanosine, DL-Laudanosine, 1699-51-0, (+-)-Laudanosine, (R,S)-Laudanosine, Laudanosine (R,S), EINECS 216-923-9, NSC 94267, AI3-61890, 20412-65-1, NSC35045, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, 5',8-Dimethoxylaudanosine hydrochloride, (+-)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline, ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-VERATRYL-, (+-)-, (1)-1-((3,4-Dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline, 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoqu inoline, SMR000064381, Veraisoquin, dl-Laudanosin, Prestwick_292, Spectrum_000863, (.+-.)-Laudanosine, SpecPlus_000088, AC1Q4CGO, Prestwick0_000591, Prestwick1_000591, Prestwick2_000591, Prestwick3_000591, Spectrum2_000663, Spectrum3_000112, Spectrum4_000934, Spectrum5_001625, (.+/-.)-Laudanosine, DL-Laudanosine, free base, D01VUF, D0F7FX, CHEMBL1407, Oprea1_379167, BSPBio_000462, BSPBio_001724, KBioGR_001488, KBioSS_001343, MLS000060551, MLS002634637, DivK1c_006184, SCHEMBL466529, SPBio_000725, SPBio_002681, AC1L264I, BPBio1_000510, ISO024, CHEBI:91599, CTK8H5184, KBio1_001128, KBio2_001343, KBio2_003911, KBio2_006479, KBio3_000864, KGPAYJZAMGEDIQ-UHFFFAOYSA-N, MolPort-001-728-151, HMS1569H04, HMS2096H04, HMS2271K11, AZD-9684, NSC94267, 6638AH, CCG-38566, NSC-35045, NSC-94267, NSC331268, AKOS001094404, AKOS022144164, MCULE-1703608488, NE49236, NSC-331268, isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, NCGC00017301-02, NCGC00142367-01, AS-37336, LS-85945, ST023493, AB00052572, FT-0625478, AB00052572-12, BRD-A24817035-001-05-4, Isoquinoline,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+/-.)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline, Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+/-.)-, Isoquinoline,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratryl-, (.+-.)-, Isoquinoline,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (+-)-, Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (+-)- (9CI), Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (.+/-.)-, Isoquinoline,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (.+-.)-

ID: 1160

InChIKey: KGQZGCIVHYLPBH-UHFFFAOYSA-N
SMILES: CC1=NC2=C(N1)C(=O)N(C(=O)N2CC3=CC=CO3)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3433
synonyms found at PubChem are:
Furafylline, 80288-49-9, Furafylline [INN], Furafilina [Spanish], Furafyllinum [Latin], UNII-C2087G0XX3, 3-Furfuryl-1,8-dimethylxanthine, 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione, CHEMBL405845, C2087G0XX3, NCGC00015426-04, DSSTox_CID_25153, DSSTox_RID_80707, DSSTox_GSID_45153, 3-(furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione, Furafilina, Furafyllinum, 3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione, 1H-Purine-2,6-dione,3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-, CAS-80288-49-9, Lopac-F-124, AC1L1FXB, AC1Q6KZJ, Lopac0_000538, SCHEMBL191214, 1,8-dimethyl-3-(2'-furfuryl)-1H-purine-2,6-dione, DTXSID2045153, CTK5E7657, Furafylline, >=98% (HPLC), KGQZGCIVHYLPBH-UHFFFAOYSA-N, MolPort-003-941-353, HMS2089A08, HMS3261L17, BCP20952, ZINC9227032, Tox21 110143, Tox21_110143, Tox21_500538, 3-(2-furylmethyl)-1,8-dimethyl-3,7-dihydro-1h-purine-2,6-dione, BDBM50236897, IN2357, AKOS027380039, Tox21_110143_1, API0026273, CCG-204628, LP00538, NCGC00015426-01, NCGC00015426-02, NCGC00015426-03, NCGC00015426-05, NCGC00015426-06, NCGC00015426-07, NCGC00015426-08, NCGC00015426-09, NCGC00093927-01, NCGC00093927-02, NCGC00093927-03, NCGC00093927-04, NCGC00261223-01, HY-107204, LS-177546, CS-0027630, EU-0100538, F-124, BIM-0050521.0001, AB01275435-01, SR-01000076233, SR-01000076233-1, 3-(2-furfuryl)-1,8-dimethyl-7H-purine-2,6-quinone, 3-(2-furylmethyl)-1,8-dimethyl-7H-purine-2,6-dione, 3-(furan-2-ylmethyl)-1,8-dimethyl-3,7-dihydro-1H-purine-2,6-dione

ID: 1161

InChIKey: KGSSUTVUTPLSQW-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(O1)C=C3C(=C2O)C(=O)C(=CO3)C4=CC5=C(C=C4)OCO5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5983661
synonyms found at PubChem are:
robustone, KBio1_001150, Spectrum_000344, SpecPlus_000110, Spectrum3_001734, Spectrum4_001545, Spectrum5_000110, BSPBio_003408, KBioGR_002010, KBioSS_000824, SPECTRUM210454, DivK1c_006206, AC1O09P3, CHEMBL252722, KBio2_000824, KBio2_003392, KBio2_005960, KBio3_002628, CCG-39587, LMPK12050245, SDCCGMLS-0066478.P001, NCGC00095520-01, NCGC00095520-02, NCGC00178085-01, BRD-K16117851-001-01-7, 7-(1,3-benzodioxol-5-yl)-5-hydroxy-2,2-dimethylpyrano[3,2-g]chromen-6-one, 22044-56-0

ID: 1162

InChIKey: KGXLWYQCBAUILI-NBHKXLOCSA-N
SMILES: CC(CCC(=O)O)[C@H]1CCC2[C@@]1(C=CC3C2CC[C@H]4[C@@]3(CCC(=O)C4)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708687
synonyms found at PubChem are:
chol-11-enic acid, KBio3_001749, Spectrum_001203, SpecPlus_000465, AC1O8FJJ, Spectrum2_000625, Spectrum3_000715, Spectrum4_001883, Spectrum5_000506, BSPBio_002529, KBioGR_002410, KBioSS_001683, DivK1c_006561, SPBio_000590, SCHEMBL18407107, KBio1_001505, KBio2_001683, KBio2_004251, KBio2_006819, CCG-39166, NCGC00178618-01, SR-05000002628, SR-05000002628-1, 4-[(5R,10S,13R,17R)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid

ID: 1163

InChIKey: KGYCKUADVHYVLM-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC3(C(O3)CCC2(C)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5024745
synonyms found at PubChem are:
2-HYDROXY-5 (6)EPOXY-TETRAHYDROCARYOPHYLLENE, KBio2_001190, Spectrum_000710, SpecPlus_000234, Spectrum2_001775, Spectrum3_001309, Spectrum4_001461, Spectrum5_000101, BSPBio_002977, KBioGR_002001, KBioSS_001190, SPECTRUM300119, DivK1c_006330, SPBio_001669, CHEMBL1562729, KBio1_001274, KBio2_003758, KBio2_006326, KBio3_002197, CCG-38424, SDCCGMLS-0066475.P001, NCGC00095589-01, NCGC00095589-02, SR-05000002483, SR-05000002483-1

ID: 1164

InChIKey: KHARQKXCINHICJ-WSPQHGNJSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@](CCCC2(C)C)(C3[C@@]1(C4=CC(=O)O[C@H]([C@@]4(CC3)C)C5=COC=C5)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708592
synonyms found at PubChem are:
KBio1_001217, Spectrum_000696, SpecPlus_000177, AC1O8FEO, Spectrum2_000261, Spectrum3_000053, Spectrum4_001335, Spectrum5_000209, BSPBio_001805, KBioGR_001829, KBioSS_001176, DEOXODEOXYDIHYDROGEDUNIN, DivK1c_006273, SPBio_000102, SCHEMBL12998461, KBio2_001176, KBio2_003744, KBio2_006312, KBio3_000985, CCG-39821, NCGC00178994-01, BRD-A98490861-001-02-7, [(1R,4bR,5R,10aS,12aR)-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-5-yl] acetate

ID: 1165

InChIKey: KHOITXIGCFIULA-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2391
synonyms found at PubChem are:
bisacodyl, 603-50-9, Dulcolax, Bicol, Brocalax, Durolax, Dulcolan, Endokolat, Fenilaxan, Hillcolax, Sanvacual, Stadalax, Theralax, Eulaxan, Godalax, Ivilax, Laxadin, Laxans, Laxine, Laxorex, Neolax, Nigalax, Pyrilax, Telemin, Ulcolax, Zetrax, Sk-bisacodyl, Laxanin N, Bisacodylum, Bisacodilo, Deficol, LACO, LA96a, Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester), HalfLytely, Bisacodylum [INN-Latin], Bisacodilo [INN-Spanish], (Pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate, Bis(p-acetoxyphenyl)-2-pyridylmethane, Di-(p-acetoxyphenyl)-2-pyridylmethane, Di-(4-acetoxyphenyl)-2-pyridylmethane, MLS000069729, UNII-10X0709Y6I, 2-(4,4'-Diacetoxydiphenylmethyl)pyridine, C22H19NO4, HSDB 3016, (4,4'-Diacetoxydiphenyl)(2-pyridyl)methane, 4,4'-(2-Pyridylmethylene)diphenol diacetate, EINECS 210-044-4, BRN 0323727, 4,4'-(2-Pyridylmethylene)diphenol diacetate (ester), 4,4'-Diacetoxydiphenylpyridyl-2-methane, SMR000058226, MLS002701749, Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate (ester), Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-diacetate, KHOITXIGCFIULA-UHFFFAOYSA-N, NSC614826, 10X0709Y6I, NCGC00016522-05, NCGC00016522-10, [4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate, CAS-603-50-9, DSSTox_CID_2681, 4,4'-(2-pyridylmethylene)bisphenol diacetate, DSSTox_RID_76689, DSSTox_GSID_22681, Q-200726, Q-200727, (pyridin-2-ylmethylene)di-4,1-phenylene diacetate, SR-01000000233, 4-[(4-acetyloxyphenyl)-2-pyridylmethyl]phenyl acetate, 4,4'-(pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate, Bisacodyle, Spirolax, CCRIS 8864, Bisacodyl [USP:INN:BAN:JAN], Bisacodyl [USAN:INN:BAN:JAN], Bisacodyl,(S), Dulcolax (TN), Prestwick_780, Feen-a-Mint Tablets, Spectrum_000086, HalfLytely (Salt/Mix), Opera_ID_884, AC1L1DKN, Prestwick0_000419, Prestwick1_000419, Prestwick2_000419, Prestwick3_000419, Spectrum2_000149, Spectrum3_000318, Spectrum4_000256, Spectrum5_000898, CHEMBL942, Correctol Tablets, Caplets, D07IEF, NCIChal_000004, NCIMech_000456, cid_2391, REGID_for_CID_2391, SCHEMBL21044, BSPBio_000378, BSPBio_001916, KBioGR_000692, KBioSS_000506, DivK1c_000347, SPECTRUM1500147, SPBio_000258, SPBio_002317, Bisacodyl (JP17/USP/INN), BPBio1_000416, CHEBI:3125, DTXSID1022681, BDBM61400, CTK8F8189, HMS501B09, KBio1_000347, KBio2_000506, KBio2_003074, KBio2_005642, KBio3_001416, EBD8044, MolPort-002-045-454, NINDS_000347, HMS1569C20, HMS1920G21, HMS2090K15, HMS2091O03, HMS2096C20, HMS2235I11, HMS3373L17, HMS3652E04, HMS3713C20, Pharmakon1600-01500147, BCP18567, HY-B0557, KS-00000FS0, ZINC3830321, Tox21_110472, Tox21_200338, CCG-35661, CCG-36442, MFCD00038039, NSC755914, s4047, SBB057015, STK293202, AKOS001599884, Tox21_110472_1, API0001726, CS-2667, DB09020, LS-2218, MCULE-8607347748, NSC-614826, NSC-755914, IDI1_000347, 4,4'-Diacetoxydiphenylpyrid-2-ylmethane, Bisacodyl, active ingredient of Viraplex, NCGC00016522-01, NCGC00016522-02, NCGC00016522-03, NCGC00016522-04, NCGC00016522-06, NCGC00016522-07, NCGC00016522-08, NCGC00016522-09, NCGC00016522-11, NCGC00016522-12, NCGC00023260-03, NCGC00023260-04, NCGC00023260-05, NCGC00023260-06, NCGC00257892-01, AC-24284, AJ-45755, AK116442, AN-46334, AS-15820, NCI60_004954, Q941, SC-18411, ST024745, SBI-0051297.P003, 4,4-(2-Pyridylmethylene)diphenol diacetate, AX8117347, AB00051928, B1898, B5066, FT-0603486, ST24026365, D00245, AB00051928-17, AB00051928_18, AB00051928_19, Bisacodyl, analytical standard, for drug analysis, A832704, Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate, SR-01000000233-2, SR-01000000233-3, (pyridin-2-ylmethanediyl)dibenzene-4,1-diyl diacetate, BRD-K39987650-001-05-0, BRD-K39987650-001-15-9, Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate, Phenol,4'-(2-pyridinylmethylene)bis-, diacetate (ester), [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate, 4-[[4-(acetyloxy)phenyl](2-pyridyl)methyl]phenyl acetate, Bisacodyl, European Pharmacopoeia (EP) Reference Standard, [4-[(4-acetyloxyphenyl)-pyridin-2-yl-methyl]phenyl] ethanoate, 4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate #, Bisacodyl, United States Pharmacopeia (USP) Reference Standard, acetic acid [4-[(4-acetyloxyphenyl)-(2-pyridinyl)methyl]phenyl] ester, Bisacodyl for peak identification, European Pharmacopoeia (EP) Reference Standard, Bisacodyl for system suitability, European Pharmacopoeia (EP) Reference Standard, Dulcolax; 4,4'-(2-Pyridylmethylene)bisphenol diacetate; [4-[(4-Acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate

ID: 1166

InChIKey: KIAIFHTWTMKEDI-XFULWGLBSA-N
SMILES: CCCN1CCC2=C3[C@H]1CC4=C(C3=CC(=C2)O)C(=C(C=C4)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10069059
synonyms found at PubChem are:
R(-)-TNPA HBr, R(-)-2,10,11-Trihydroxy-N-propylnoraporphine hydrobromide, R(-)-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate, 77630-02-5, EU-0100455, R(-)-2-OH-NPA HBr, SCHEMBL1325232, CHEMBL1613539, CTK8G2717, DTXSID00435151, Tox21_500455, CCG-221759, LP00455, NCGC00261140-01, 79640-85-0, VU0288799-2, R(-)-TNPA HBr; R(-)-2-OH-NPA hydrobromide, SR-01000075372, SR-01000075372-1, R(-)-2,10,11-Thrihydroxy-N-propylnorapomorphine hydrobromide

ID: 1167

InChIKey: KJADKKWYZYXHBB-XBWDGYHZSA-N
SMILES: CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5284627
synonyms found at PubChem are:
topiramate, Topamax, 97240-79-4, Epitomax, Topamax Sprinkle, Tipiramate, Topiramatum, McN-4853, Tipiramato, Topiramato, Tipiramate [French], Tipiramato [Spanish], Topiramatum [INN-Latin], topiramatum [Latin], Topiramato [INN-Spanish], McN 4853, Topimax, Topomax, Topina, RWJ-17021, Epitoma, Topamac, Topiramic acid, topiramate tablet, RWJ-17021-000, Topiramate (TPM), Topamax (TN), Topiramate [USAN:BAN:INN], UNII-0H73WJJ391, 2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate, C12H21NO8S, Topiramate / Placebo, 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, BRN 5988957, Topiramate (JAN/USAN/INN), CHEBI:63631, USL-255, 0H73WJJ391, RWJ 17021, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate, KS-1122, KW-6485, beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate, DSSTox_CID_3688, DSSTox_RID_77148, DSSTox_GSID_23688, Topiragen, Topax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate, Trokendi XR, Qudexy XR, ((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate, ((3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl)methyl sulfamate, [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate, SMR000466325, TOR, CAS-97240-79-4, USL255, HSDB 7531, Sulfamate 7, 3hku, 3lxe, USL 255, Topiramate [USAN:USP:INN:BAN], NCGC00095181-01, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[5,4-b:5',3'-d]pyran-3a-yl]methyl sulfamate, Topamax, Topiramate, Trokendi xr (TN), Cilag brandof topiramate, Ortho brand of topiramate, Spectrum2_001128, CBChromo1_000352, D07VDZ, Janssen brand of topiramate, BIDD:PXR0127, SCHEMBL34631, BSPBio_002306, MLS000759431, MLS001424070, BIDD:GT0854, SPECTRUM1505801, SPBio_000995, CHEMBL220492, FRU009, GTPL6849, DTXSID8023688, BDBM10887, KJADKKWYZYXHBB-XBWDGYHZSA-N, MolPort-001-615-062, HMS1922H06, HMS2051L09, HMS2093D20, HMS2232H21, HMS3715I12, Pharmakon1600-01505801, ACT09031, ALBB-022457, HY-B0122, Tox21_111472, Tox21_302401, 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, KM3440, MFCD00865320, NSC759251, s1438, ZINC95616603, AKOS000424547, Topiramate 1.0 mg/ml in Acetonitrile, Topiramate, >=98% (HPLC), solid, Tox21_111472_1, API0004451, CCG-100940, CS-1885, DB00273, MCULE-9403222429, NC00190, NSC-759251, NCGC00178714-01, NCGC00178714-04, NCGC00255221-01, AN-14917, CC-35104, CPD000466325, KB-61804, LS-69764, SAM001246601, SC-16371, SBI-0206907.P001, AB0007831, AB1009630, LS-187392, TL8006021, C07502, D00537, AB00639961-06, AB00639961-08, AB00639961_09, AB00639961_10, 240T794, C-20295, SR-01000759409, W-60376, 5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, beta, Q-201845, SR-01000759409-4, Z1522553470, 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate, 2,3:4,5-di-o-isopropylidene-(beta)-d-fructopyranose sulfamate, Topiramate, United States Pharmacopeia (USP) Reference Standard, 2,3:4,5-Bis-O-(1-methylethylidene)-?-D-fructopyranose sulfamate, 2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate, 2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate, beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material, Beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI), [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0;{2,6}]dodecan-6-yl]methyl sulfamate, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl sulfamate

ID: 1168

InChIKey: KJFMBFZCATUALV-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)OC2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4764
synonyms found at PubChem are:
phenolphthalein, 77-09-8, Phthalimetten, Euchessina, Phthalin, Espotabs, Phenolax, Purgophen, Koprol, Laxogen, Trilax, Purga, Lilo, Spulmako-lax, Chocolax, Feen-A-Mint Gum, Purgen, 3,3-Bis(4-hydroxyphenyl)phthalide, Ex-Lax, Fenolftalein, Correctol, Alophen, Doxidan, Medilax, Colax, Laxin, FemiLax, Dihydroxyphthalophenone, Phillips Gelcaps, 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone, Lax-Pills, Evac-Q-Kwik, Evac-Q-Tabs, Evac-Q-Kit, Evac-U-Gen, 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-, Fenolftaleina, Phenolphtaleine, Phenophthalein, Laxcaps, Agoral, Doxan, Fenolftalein [Czech], Phenolphthaleinum, 3,3-Bis(p-hydroxyphenyl)phthalide, 3,3-Bis(4-hydroxyphenyl)isobenzofuran-1(3H)-one, Evac-V-Lax, NCI-C55798, Feen-A-Mint Laxative Mints, Fenolftaleina [INN-Spanish], Phenolphtaleine [INN-French], Phenolphthaleinum [INN-Latin], alpha-Di(p-hydroxyphenyl)phthalide, 3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3H)-one, UNII-6QK969R2IF, NSC 10464, component of Agoral, Phthalide 3,3,-bis(p-hydroxyphenyl)-, CCRIS 6266, HSDB 4161, 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one, EINECS 201-004-7, BRN 0284423, CHEMBL63857, AI3-09081, MLS000069592, 6QK969R2IF, CHEBI:34914, KJFMBFZCATUALV-UHFFFAOYSA-N, component of Correctol, NCGC00018200-07, SMR000059015, 3,3-bis(4-hydroxyphenyl)isobenzofuran-1-one, DSSTox_CID_1125, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, alpha-(p-Hydroxyphenyl)-alpha-(4-oxo-2,5-cyclohexadien-1-ylidene)-o-toluic acid, DSSTox_RID_75956, DSSTox_GSID_21125, 3,3-bis(4-hydroxyphenyl)-3-hydroisobenzofuran-1-one, component of Feen-A-Mint Pills, Laxettes, Phthalide 3,-bis(p-hydroxyphenyl)-, Feen-a-mint, CAS-77-09-8, Phenolphthalein Solution, Alcoholic 1.0%, WLN: T56 BVO DHJ D- D-/R DQ 2, 1(3H)-Isobenzofuranone,3-bis(4-hydroxyphenyl)-, 3, 3-Bis(p-hydroxyphenyl)-1(3H)-isobenzofuranone, Phenolphthalein [INN:BAN], phenolphtalein, Figsen, Laxett es, Phenolphthalein [USP:INN:BAN], Doxan (Salt/Mix), Phenolphthalein,white, Agoral (Salt/Mix), Modane (TN), Phenolphthalein,(S), Laxcaps (Salt/Mix), Phenolphthalein,yellow, Yellow phenolphthalein, PubChem7084, Phenolphthalein (INN), Spectrum_001077, AC1L1IWH, Opera_ID_1337, Spectrum2_001279, Spectrum3_000888, Spectrum4_000982, Spectrum5_001268, Modane Plus (Salt/Mix), D03FDT, EC 201-004-7, Phenolphthalein ACS reagent, PHENOLPHTHALEIN, ACS, cid_4764, Phenolphthalein, ACS reagent, SCHEMBL27670, BSPBio_002518, KBioGR_001383, KBioSS_001557, Phenolphthalein, pH indicator, 5-18-04-00188 (Beilstein Handbook Reference), MLS001148397, BIDD:ER0202, DivK1c_000929, Phenolphthalein, ACS 100g, SPECTRUM1500480, Phenolphthalein Paper, DAB 6, SPBio_001278, AC1Q78Q2, ARONIS002962, DTXSID0021125, BCBcMAP01_000174, HMS502O11, KBio1_000929, KBio2_001557, KBio2_004125, KBio2_006693, KBio3_001776, KS-00000YJD, Phenolphthalein solution, 0.1 N, MolPort-001-011-548, NINDS_000929, HMS1920H04, HMS2091P06, HMS2236I09, HMS3374P06, LS-47, Pharmakon1600-01500480, component of Correctol (Salt/Mix), HY-D0211, KS-00003W2P, NSC10464, ZINC3831317, Phenolphthalein, p.a., ACS reagent, Tox21_110838, Tox21_202219, Tox21_300282, BBL002030, BDBM50077844, CCG-39112, MFCD00005913, NSC-10464, NSC215214, NSC757271, PHENOLPHTHALEIN U.S.P./N.F., SBB008868, STK029876, AKOS000493033, Tox21_110838_1, CS-8152, DB04824, MCULE-5232154932, NE46883, NSC-215214, NSC-757271, RL04943, IDI1_000929, SMP1_000235, NCGC00018200-01, NCGC00018200-02, NCGC00018200-03, NCGC00018200-04, NCGC00018200-05, NCGC00018200-06, NCGC00018200-08, NCGC00018200-09, NCGC00018200-10, NCGC00018200-12, NCGC00023694-03, NCGC00023694-04, NCGC00023694-05, NCGC00023694-06, NCGC00023694-07, NCGC00254039-01, NCGC00259768-01, AC-14431, AJ-45783, AN-23907, BP-30100, SC-74728, ST072636, SBI-0051481.P003, component of Feen-A-Mint Pills (Salt/Mix), TR-037762, 2-[Bis (4-hydroxyphenyl)methyl]benzoic acid, EU-0082600, FT-0659094, P0094, P0700, P0701, P0702, ST24041105, T8172, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-on, EN300-92962, Phenolphthalein, SAJ first grade, >=97.0%, .alpha., .alpha.-Di(p-hydroxyphenyl)phthalide, 3,3-bis (4-hydroxyphenyl)-2-benzofuran-1-on, C14286, D05456, Phenolphthalein, JIS special grade, >=98.0%, AB00052070_15, SR-01000000112, 3,3-bis[4-Hydroxyphenyl]-1-[3H]-isobenzofuranone, I01-9729, I06-1896, Q-201555, SR-01000000112-2, TRANSGENIC MODEL EVALUATION (PHENOLPHTHALEIN), 3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3H)-one #, 3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one, 3,3-bis[4-Hydroxyphenyl]-1-[3H]- isobenzofuranone, BRD-K19227686-001-02-0, BRD-K19227686-001-12-9, Phenolphthalein solution, 1 % (w/v), pH 7.8-10.0, Z57233591, F0921-4309, TRANSGENIC MODEL EVALUATION II (PHENOLPHTHALEIN), Phenolphthalein solution, 0.04 % (w/v), pH 7.8-10.0, Phenolphthalein solution, 0.1 % (w/v), pH 7.8-10.0, Phenolphthalein solution, 0.5 wt. % in ethanol: water (1:1), Phenolphthalein, United States Pharmacopeia (USP) Reference Standard, 390417-24-0, 467-29-8, 546094-13-7, 57214-20-7, InChI=1/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22, Phenolphthalein, ACS reagent, reag. Ph. Eur., indicator, 98-102% (calc. to the dried substance), S. No.: 879, Phenolphthalein, puriss., meets analytical specification of Ph??Eur., BP, 98-101% (calc. to the dried substance)

ID: 1169

InChIKey: KJHHAPASNNVTSN-KPKJPENVSA-N
SMILES: COC1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 641818
synonyms found at PubChem are:
4'-Methoxychalcone, 959-23-9, 1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, (2E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, (E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, CHEMBL34398, 1-(4-methoxyphenyl)-3-phenyl-2-propen-1-one, ST059919, UNII-BM45N45FIZ, (E)-1-(4-Methoxy-phenyl)-3-phenyl-propenone, AF-961/00496034, 2-propen-1-one, 1-(4-methoxyphenyl)-3-phenyl-, (2E)-, 2-Propen-1-one, 1-(4-methoxyphenyl)-3-phenyl-, 22966-19-4, BM45N45FIZ, 4/'-Methoxychalcone, methoxychalcone, 4'-, Styryl p-anisyl ketone, 4' - Methoxychalcone, rarechem am uc 0609, Spectrum5_000236, (E)-4'-Methoxychalcone, 4'-methoxychalcone 97%, AC1LD3N5, BSPBio_002861, SPECTRUM211475, 4-Methoxyphenyl styryl ketone, MEGxp0_001883, ACon1_000177, 4'-Methoxychalcone, 97% 5g, KJHHAPASNNVTSN-KPKJPENVSA-N, MolPort-000-473-981, MolPort-019-724-211, NSC37157, ZINC4175546, ZX-AT024193, 2-benzylidene-4'-methoxyacetophenone, 4482AF, BBL001822, BDBM50141532, LMPK12120188, NSC-37157, SBB012444, STK831846, AKOS001325034, CCG-214164, MCULE-9150634071, SDCCGMLS-0066535.P001, ACM22966194, NCGC00095535-01, NCGC00095535-02, NCGC00095535-03, NCGC00095535-04, CC-19765, TS-00699, 1-(4-Methoxy-phenyl)-3-phenyl-propenone, AB0093160, KB-147403, TR-038586, A-7217, AB00375841-02, E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one, SR-05000002481, 1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (6), SR-05000002481-1, BRD-K09233738-001-04-4, InChI=1/C16H14O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-12H,1H3/b12-7

ID: 1170

InChIKey: KJQFBVYMGADDTQ-CVSPRKDYSA-N
SMILES: CCCCS(=N)(=O)CC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 119565
synonyms found at PubChem are:
L-Buthionine-sulfoximine, l-buthionine sulfoximine, 83730-53-4, (2S)-2-Amino-4-(butylsulfonimidoyl)butanoic acid, L-Buthionine-(S,R)-sulfoximine, l-buthionine(s,r)-sulfoximine, L-BSO, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-, NSC 326231, L-Buthionine (SR)-sulfoximine, Buthionine-S,R-sulfoximine, L-, L-Buthionine-(S,R)-sulphoximine, Buthionine sulfoximine, L-, AC1Q6THM, (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic Acid, BUTHIONINE SULFOXIME, NCIMech_000342, AC1L3P1K, Lopac0_000221, SCHEMBL62034, CHEMBL261642, D,L-Buthionine-S,R-sulfoximine, CHEBI:94288, MolPort-002-559-281, HMS3260N03, BSO, Tox21_500221, MFCD00067000, 1-beta-DL-Buthionine(S,R)sulfoximine, AKOS027320570, LP00221, MCULE-5971306528, NSC-326231, KS-00000Y54, NCGC00093690-01, NCGC00093690-02, NCGC00093690-03, NCGC00260906-01, L-Buthionine-sulfoximine, >=97% (TLC), EU-0100221, FT-0627738, B 2515, SR-01000075712, SR-01000075712-1, BRD-A47706533-001-01-8, UNII-EEY8DZS103 component KJQFBVYMGADDTQ-JKYUHCHBSA-N, UNII-LW4108Q0BV component KJQFBVYMGADDTQ-JKYUHCHBSA-N, (R*,S*)-(+-)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid, Butanoic acid, 2-amino-4-((R)-S-butylsulfonimidoyl)-, (2S)-rel-, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (R*,S*)-(+-)-, 97590-40-4, AC1LU7IX, 2-amino-4-(S-butylsulfonimidoyl)butanoate, (2S)-2-ammonio-4-(S-butylsulfonimidoyl)butanoate, (2S)-2-azaniumyl-4-(butylsulfonimidoyl)butanoate

ID: 1171

InChIKey: KJQFBVYMGADDTQ-UHFFFAOYSA-N
SMILES: CCCCS(=N)(=O)CCC(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 21157
synonyms found at PubChem are:
BUTHIONINE SULFOXIMINE, 5072-26-4, DL-Buthionine-[S,R]-sulfoximine, Buthionine sulfoxamine, Buthionine sulphoximine, Buthione sulfoximine, Buthionine-S,R-sulfoximine, 2-Amino-4-(S-butylsulfonimidoyl)butanoic acid, Butionine sulfoximine, 2-Amino-4-(butylsulfonimidoyl)butanoic acid, DL-Buthionine-sulfoximine, NSC 381100, Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, BRN 2367136, DL-Buthionine-S,R-sulfoximine, CHEBI:28714, DL-Buthionine-(S,R)-sulfoximine, D,L-Buthionine-(S,R)-sulfoximine, DL-butathionine-(S,R)-sulfoximine, Sulfoximine, S-(3-amino-3-carboxypropyl)-S-butyl-, NSC326231, NSC381100, S-butyl-DL-homocysteine (S,R)-sulfoximine, S-Butyl-DL-homocysteine-[S,R]-sulfoximine, 2-amino-4-(S-butylsulfonimidoyl)butyric acid, NSC 326231, 71765-30-5, C8H18N2O3S, L-Buthionine (SR)-sulfoximine, Buthionine-S,R-sulfoximine, L-, L-Buthionine-(S,R)-sulphoximine, dl-buthionine (s,r)-sulfoximine, BSO, beta-Glutamylcysteine, AC1L2HQW, D0K8LM, Lopac0_000231, SCHEMBL62033, BSPBio_002464, SPECTRUM1505108, CHEMBL1256575, CHEMBL1627290, DTXSID6044434, CTK8F8906, OR9025T, KJQFBVYMGADDTQ-UHFFFAOYSA-N, MolPort-001-770-865, HMS3260P03, BCP24029, BCP27775, KS-000018ET, ZX-AT019574, Tox21_500231, MFCD00070309, S-(n-butyl)homo cysteine sulfoximine, STL328818, AKOS022106364, API0009406, CCG-204326, DB12870, LP00231, MCULE-8178742509, NSC-381100, NCGC00015148-03, NCGC00015148-04, NCGC00015148-05, NCGC00015148-06, NCGC00015148-07, NCGC00093696-01, NCGC00093696-02, NCGC00093696-03, NCGC00260916-01, LS-46081, LS-46082, NCI60_002827, EU-0100231, FT-0624379, ST51012445, 2-Amino-4-(butylsulfonimidoyl);butanoic acid, DL-Buthionine-sulfoximine, >=99.0% (TLC), 2-Amino-4-(butylsulfonimidoyl)butanoic acid #, 2-Amino-4-(S-butylsulfoninidoyl)butanoic acid, 2-Amino-4-(S-butylsulphonimidoyl)butanoic acid, B 2640, C04543, S-(3-Amino-3-carboxypropyl)-S-butylsulphoximine, SR-01000075713, SR-01000075713-1, (S)-2-Amino-4-((R)-butylsulfonimidoyl)butanoic acid, BRD-A04020513-001-01-9, 2-amino-4-[butyl(imino)oxo-|E6-sulfanyl]butanoic acid, AC1MS6SH, D0Z6VR, 2-azaniumyl-4-(butylsulfonimidoyl)butanoate

ID: 1172

InChIKey: KJTDZAHLWHEULN-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(O1)C=CC(=C2OC)C3=COC4=CC5=C(CC(C(O5)(C)C)O)C=C4C3=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4587968
synonyms found at PubChem are:
Mundulone, 481-94-7, KBio1_001296, SpecPlus_000256, Spectrum2_000289, Spectrum3_001264, Spectrum4_002000, AC1NE80K, BSPBio_002828, KBioGR_002567, SPECTRUM200011, DivK1c_006352, SPBio_000198, CHEMBL465339, SCHEMBL3728738, CTK8I8465, KBio3_002328, CCG-39847, LMPK12050079, SDCCGMLS-0066391.P001, NCGC00095461-01, NCGC00095461-02, NCGC00178449-01, SR-05000002670, SR-05000002670-1, BRD-A93572202-001-02-5, BRD-A93572202-001-03-3, (-)-3,4-Dihydro-3-hydroxy-7-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one, 2H,6H-Benzo(1,2-b:5,4-b')dipyran-6-one, 3,4-dihydro-3-hydroxy-7-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-2,2-dimethyl-, (-)-, 3-hydroxy-7-(5-methoxy-2,2-dimethyl-chromen-6-yl)-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-6-one, 3-hydroxy-7-(5-methoxy-2,2-dimethylchromen-6-yl)-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-6-one

ID: 1173

InChIKey: KJZZTCSJZCYCQS-RFVHGSKJSA-N
SMILES: C[C@H](CC1=CC=CC=C1)NCC#C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9855833
synonyms found at PubChem are:
R-(-)-Desmethyldeprenyl hydrochloride, L-Nordeprenyl hydrochloride, desmethylselegiline hydrochloride, UNII-LN8SH3P9VL, 115586-38-4, LN8SH3P9VL, Selegiline related compound D, (-)-Nordeprenyl hydrochloride, Selegiline related compound D [USP], Selegiline related compound D RS [USP], MLS002153335, SCHEMBL2473190, CHEMBL1256013, (R)-N-Desmethyl Selegiline HCl, DTXSID70151139, Tox21_500461, API0008854, CCG-221765, LP00461, Benzeneethanamine, alpha-methyl-N-2-propyn-1-yl-, hydrochloride (1:1), (alphaR)-, N-Desmethyl Selegiline D5 Hydrochloride, NCGC00093875-01, NCGC00261146-01, ACM115586384, SMR001230748, EU-0100461, D 6940, SR-01000075828, J-003308, SR-01000075828-1, Selegiline Related Compound D, United States Pharmacopeia (USP) Reference Standard, KJZZTCSJZCYCQS-RFVHGSKJSA-N, N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-aminium chloride

ID: 1174

InChIKey: KKAJSJJFBSOMGS-UHFFFAOYSA-N
SMILES: C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6842
synonyms found at PubChem are:
3,6-DIAMINO-10-METHYLACRIDINIUM CHLORIDE, Chromoflavine, Flavosan, Gonacrine, Gonocrin, Trypaflavin, Burnol, Avlon, Panflavin, Neutroflavine, Xanthacridine, Acriflavon, 86-40-8, Flavine, C.I. 46000, UNII-1TW3Q60E36, CCRIS 2116, ACRIFLAVINIUM HYDROCHLORIDE, NSC 2755, EINECS 201-668-8, Acridinium, 3,6-diamino-10-methyl-, chloride, CHEBI:383703, 1TW3Q60E36, Acridinium, 3,6-diamino-10-methyl-, chloride (1:1), Acriflavine (component of), 837-73-0 (Parent), NSC2755, 10-methylacridine-3,6-diamine, chloride, Acridinium,6-diamino-10-methyl-, chloride, WLN: T C666 BKJ B1 EZ MZ &Q &G, SR-05000002063, Trypaflavine, 10-methylacridin-10-ium-3,6-diamine chloride, AC1L1NFA, AC1LD8LF, AC1Q1RWW, SCHEMBL77746, MLS002207308, SPECTRUM1500618, CHEMBL354349, CTK5F6614, HMS500M06, DTXSID60273975, HMS1921K15, HMS2092E08, Pharmakon1600-01500618, NSC-2755, NSC47700, CCG-39873, NSC-47700, NSC757387, SBB003092, AKOS023249367, NSC-757387, NCGC00094813-02, LS-14522, SMR001306813, FT-0621869, ST50999664, 3,6-diamino-10-methylacridin-10-ium chloride, SR-05000002063-1, SR-05000002063-2, Acridinium,3,6-diamino-10-methyl-, chloride (1:1), UNII-1T3A50395T component KKAJSJJFBSOMGS-UHFFFAOYSA-N

ID: 1175

InChIKey: KKSDGJDHHZEWEP-SNAWJCMRSA-N
SMILES: C1=CC(=CC(=C1)O)/C=C/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JC Fulton" "M Mazur" "PA Sloane" "SM Rowe" "JP Clancy" "J Prasain" "S Barnes" "K Backer" "LC Pyle"

CID is 637541
synonyms found at PubChem are:
3-Hydroxycinnamic acid, 14755-02-3, 3-Coumaric acid, 588-30-7, M-COUMARIC ACID, m-Hydroxycinnamic acid, (E)-3-(3-Hydroxyphenyl)acrylic acid, trans-3-Hydroxycinnamic acid, 3-(3-Hydroxyphenyl)acrylic acid, trans-3-Hydroxycinnamate, Cinnamic acid, m-hydroxy-, (2E)-3-(3-hydroxyphenyl)prop-2-enoic acid, trans-3-coumaric acid, (2E)-3-(3-hydroxyphenyl)acrylic acid, (E)-3-(3-Hydroxyphenyl)-2-propenoic acid, UNII-KWJ2DDJ34H, 2-Propenoic acid, 3-(3-hydroxyphenyl)-, 2-propenoic acid, 3-(3-hydroxyphenyl)-, (2E)-, trans-m-Coumaric Acid, (E)-3-(3-hydroxyphenyl)prop-2-enoic acid, (2E)-3-(3-Hydroxyphenyl)-2-propenoic acid, NSC 28956, NSC 50308, KWJ2DDJ34H, 3-(3-hydroxyphenyl)-2-propenoic acid, CHEMBL98521, 3-(3-Hydroxyphenyl)acrylsaeure, CHEBI:32357, KKSDGJDHHZEWEP-SNAWJCMRSA-N, 2-Propenoic acid, 3-(3-hydroxyphenyl)-, (E)-, 3-hydroxycinnamate, trans-3-coumarate, 3-(3-hydroxyphenyl)prop-2-enoic acid, (2E)-3-(3-hydroxyphenyl)prop-2-enoate, 3-(3-hydroxyphenyl)acrylate, 3-(3-hydroxyphenyl)prop-2-enoate, (2E)-3-(3-hydroxyphenyl)acrylate, (E)-3-(3-hydroxyphenyl)-2-propenoate, m-Coumarate, 3-(3-Hydroxy-phenyl)-acrylic acid, m-Hydroxycinnamate, m-hydroxy-Cinnamate, EINECS 209-615-0, 3'-Hydroxycinnamate, trans-m-Cumaric Acid, PubChem8222, AC1LCUFW, m-hydroxy-Cinnamic acid, 3'-Hydroxycinnamic acid, 3-Hydroxy cinnamic acid, AI3-32389, 3/'-Hydroxycinnamic acid, bmse000093, 3-Hydroxyphenylacrylic acid, Cinnamic acid, 3-hydroxy-, SCHEMBL442408, Jsp002754, CHEBI:47925, MolPort-000-886-288, MolPort-023-134-755, ZINC155996, 3-(3-hydroxyphenyl)-2-Propenoate, ACT02256, ALBB-006261, NSC28956, NSC50308, m-Coumaric acid, analytical standard, trans-3-Hydroxycinnamic acid, 99%, BBL013143, BDBM50146456, MFCD00004390, NSC-28956, NSC-50308, SBB057740, STK400397, AKOS000146568, 2-Propenoicacid,3-(3-hydroxyphenyl)-, 3-(3-hydroxyphenyl)-(2E)-propenoate, RP17400, RTR-005890, (E)-3-(3-hydroxyphenyl)-acrylic acid, (E)-3-(3-hydroxy-phenyl)-acrylic acid, (2E)-3-(3-hydroxyphenyl)-2-propenoate, AC-16619, AJ-13662, AN-46147, AS-12450, BC210626, KB-02461, M680, SC-80962, ST097477, 3-(3-Hydroxyphenyl)-(2E)-propenoic acid, AB0011960, AB1003732, HY-113357, KB-183004, TC-169569, TR-005890, BB 0256480, CS-0062284, ST24028291, B-7286, C12621, J10101, M-2958, 2-Propenoic acid, 3-(3-hydroxyphenyl)- (9CI), 2-Propenoic acid,3-(3-hydroxyphenyl)-, (2E)-, A832036, I01-6597, J-501891, 358818FD-674F-4656-96AF-40F17C30F2EE, InChI=1/C9H8O3/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-6,10H,(H,11,12)/b5-4

ID: 1176

InChIKey: KMJPKUVSXFVQGZ-WQLSNUALSA-N
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C4=C(C(=O)C=C(C=C34)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 169167
synonyms found at PubChem are:
30462-34-1, THEAFLAVIN MONOGALLATES, Theaflavin monogallate A, [(2R,3R)-5,7-dihydroxy-2-[3,4,5-trihydroxy-6-oxo-1-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-8-yl]-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, Spectrum_000318, SpecPlus_000279, AC1Q6AEI, Spectrum2_000162, Spectrum3_000252, Spectrum4_001542, Spectrum5_000104, BSPBio_001664, KBioGR_002004, KBioSS_000798, (2r,3r)-5,7-dihydroxy-2-{3,4,6-trihydroxy-5-oxo-1-[(2r,3r)-3,5,7-trihydroxy-3,4-dihydro-2h-chromen-2-yl]-5h-benzo[7]annulen-8-yl}-3,4-dihydro-2h-chromen-3-yl 3,4,5-trihydroxybenzoate, DivK1c_006375, SPBio_000023, Theaflavin -3-gallate(TF2A), AC1L539F, CHEMBL3039319, SCHEMBL13300897, SCHEMBL16909926, CTK4G5231, KBio1_001319, KBio2_000798, KBio2_003366, KBio2_005934, KBio3_001164, DTXSID90184540, MolPort-044-831-687, ZINC3978504, CCG-38375, AKOS027326812, SDCCGMLS-0066974.P001, NCGC00179102-01, SR-05000002777, SR-05000002777-1, 3,4,6-Trihydroxy-8-[[(2R)-3,4-dihydro-5,7-dihydroxy-3alpha-(3,4,5-trihydroxybenzoyloxy)-2H-1-benzopyran]-2alpha-yl]-1-[[(2R)-3,4-dihydro-3alpha,5,7-trihydroxy-2H-1-benzopyran]-2alpha-yl]-5H-benzocyclohepten-5-one, Benzoic acid, 3,4,5-trihydroxy-, 2-(1-(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5-oxo-5H-benzocyclohepten-8-yl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2R-(2alpha(2R*,3R*),3alpha))-, Benzoic acid,3,4,5-trihydroxy-,(2R,3R)-2-[1-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohepten-8-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-ylester, InChI=1/C36H28O16/c37-14-5-20(39)18-10-26(45)35(51-27(18)7-14)17-9-25(44)33(48)30-16(17)1-12(2-24(43)32(30)47)34-29(11-19-21(40)6-15(38)8-28(19)50-34)52-36(49)13-3-22(41)31(46)23(42)4-13/h1-9,26,29,34-35,37-42,44-46,48H,10-11H2,(H,43,47)/t26-,29-,34-,35-/

ID: 1177

InChIKey: KMSRVXJGTIRNNK-UHFFFAOYSA-N
SMILES: C(=N)(N)N.C(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 286947
synonyms found at PubChem are:
carbonic acid - guanidine (1:1), 124-46-9, 100224-74-6, 1177135-38-4, guanidinium bicarbonate, Spectrum_000137, ACMC-1AKYH, AC1Q5WWP, Spectrum2_000849, Spectrum3_000767, Spectrum4_000790, Spectrum5_001568, AC1L66BR, SCHEMBL5102, KBioGR_001240, KBioSS_000597, KSC172G3T, DivK1c_000463, Guanidine; carbonate (1:1), SPECTRUM1500761, SPBio_000837, CTK0H2339, HMS501H05, KBio1_000463, KBio2_000597, KBio2_003165, KBio2_005733, KBio3_001634, KS-00000VJR, NSC2171, KMSRVXJGTIRNNK-UHFFFAOYSA-N, MolPort-002-317-307, NINDS_000463, NSC-2171, ANW-33252, BBL002806, CCG-40303, NSC146175, STK397351, AKOS005449506, MCULE-9649225484, NSC-146175, RP19400, RTR-031654, IDI1_000463, TRA-0205274, NCGC00095741-02, BC211195, KB-52308, TR-031654, T8404, I14-6750, J-521419, guanidinium hydrogen carbonate, guanidinium hydrogen car-bonate

ID: 1178

InChIKey: KNADXBVKFAUMCR-UHFFFAOYSA-N
SMILES: CCCN(CC1CC1)C2=NC(=NC(=C2Cl)NC3=C(C=C(C=C3Cl)Cl)Cl)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 176157
synonyms found at PubChem are:
NBI 27914, NBI27914, NBI-27914, CHEMBL45281, 184241-44-9, SR-01000075865, Tocris-1591, 5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)aminopyridine, Lopac-N-3911, D04KWH, D0P4YG, AC1L41YH, Lopac0_000493, MLS000860080, cid_176157, GTPL3512, SCHEMBL16606734, CHEBI:93069, Des-Arg(9)-[Leu(8)]-BK, DTXSID20171549, HMS2230I15, HMS3261D07, HMS3371C20, ZINC2511843, Tox21_500493, BDBM50054245, API0008466, CCG-204584, LP00493, 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine, NCGC00015737-01, NCGC00015737-02, NCGC00015737-03, NCGC00015737-04, NCGC00015737-05, NCGC00025224-01, NCGC00025224-02, NCGC00025224-03, NCGC00261178-01, SMR000326938, LS-186073, EU-0100493, NBI 27914, >=98% (HPLC), N 3911, SR-01000075865-1, BRD-K61177364-003-01-1, 4,6-Pyrimidinediamine, 5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-n-(2,4,6-trichlorophenyl), 4,6-Pyrimidinediamine, 5-chloro-N-(cyclopropylmethyl0-2-methyl-N-propyl-n-(2,4,6-trichlorophenyl), 5-Chloro-4-(N-(cyclopropyl)methyl-N-propylamino)-2-methyl-6-(2,4,6-trichlorophenyl)-aminopyridine, 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine, 5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine, 5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''''-(2,4,6-trichloro-phenyl)-pyrimidine-4,6-diamine, 5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''-(2,4,6-trichloro-phenyl)-pyrimidine-4,6-diamine

ID: 1179

InChIKey: KNAHARQHSZJURB-UHFFFAOYSA-N
SMILES: CCCC1=CC(=O)NC(=S)N1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4950
synonyms found at PubChem are:
propylthiouracil, 51-52-5, 6-Propyl-2-thiouracil, Propacil, Prothiurone, Prothyran, Procasil, Propycil, Prothiucil, Protiural, Thiuragyl, Prothycil, 2-Mercapto-6-propylpyrimidin-4-ol, Propyl-Thiorist, Propyl-Thyracil, 6-N-Propylthiouracil, Propythiouracil, Propilthiouracil, Propyl-Thiorit, Propylthiorit, 6-Propylthiouracil, Propylthiouracile, Thyreostat II, Propiltiouracilo, 6-N-Propyl-2-thiouracil, 6-Thio-4-propyluracil, 6-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, PTU (thyreostatic), Propylthiouracilum, 4-Propyl-2-thiouracil, 2-Mercapto-6-propyl-4-pyrimidone, 6-Propil-tiouracile, Propiltiouracile, Uracil, 6-propyl-2-thio-, 2-Mercapto-6-propylpyrimid-4-one, 2-Thio-6-propyl-1,3-pyrimidin-4-one, 2-Thio-4-oxo-6-propyl-1,3-pyrimidine, Propiltiouracile [DCIT], 4-Hydroxy-2-mercapto-6-propylpyrimidine, 2-Mercapto-4-hydroxy-6-n-propylpyrimidine, 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone, 6-Propil-tiouracile [Italian], Propiltiouracilo [INN-Spanish], PROPYL THIOURACIL, Propylthiouracile [INN-French], Propylthiouracilum [INN-Latin], 4(1H)-Pyrimidinone, 2,3-dihydro-6-propyl-2-thioxo-, thyreos tat ii, ptu(thyreostatic), NSC 6498, 6-Propyl-2-thio-2,4(1H,3H)pyrimidinedione, CCRIS 544, CHEBI:8502, UNII-721M9407IY, Propylthiouracil (TN), HSDB 3390, Propylthiouracil [INN:BAN:JAN], 6-propyl-2 thiouracil, 6-propyl-2-sulfanylidene-1H-pyrimidin-4-one, 6-Prop yl-2-thiouracil, thyreostat propyl-thyracil, EINECS 200-103-2, 6-(n-Propyl)-2-thiouracil, AI3-25477, MLS000028494, 500-50-5, KNAHARQHSZJURB-UHFFFAOYSA-N, 6-propyl-2-sulfanylpyrimidin-4-ol, 721M9407IY, 53939-84-7, 6-propyl-2-thioxo-1H-pyrimidin-4-one, CAS-51-52-5, NCGC00022715-03, 2-mercapto-6-propylpyrimidin-4(3H)-one, HC210060, SMR000058275, DSSTox_CID_1209, 6-Propyl-2-thio-2,4(1H,3H)-pyrimidinedione, 6-propyl-2-thiopyrimidine-2,4(1H,3H)-dione, DSSTox_RID_76011, 6-n-PROPYL-2-MERCAPTO-4-HYDROXYPYRIMIDINE, 6-propyl-2-sulfanyl-3,4-dihydropyrimidin-4-one, DSSTox_GSID_21209, WLN: T6MYMVJ BUS F3, 6-Propyl-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one, 6-propyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one, 6-Propyl-2-thio-2,3H)-pyrimidinedione, 6 Propyl 2 Thiouracil, SR-05000001706, 4(1H)-Pyrimidinone,3-dihydro-6-propyl-2-thioxo-, Propyl thiouracile, 3CJ, Prestwick_810, Propylthiouracil [USP:INN:BAN:JAN], AC1LCWBA, Spectrum_000876, ACMC-1AMSS, Opera_ID_530, Prestwick0_000494, Prestwick1_000494, Prestwick2_000494, Prestwick3_000494, Spectrum2_001302, Spectrum3_001731, Spectrum4_000492, Spectrum5_001815, D00MIN, D0K2MK, CHEMBL1518, SCHEMBL41239, BSPBio_000387, BSPBio_003402, KBioGR_001003, KBioSS_001356, KSC492M9T, MLS002303010, MLS006011901, DivK1c_000268, SPECTRUM1500515, SPBio_001363, SPBio_002308, BPBio1_000427, GTPL6650, DTXSID5021209, SCHEMBL17375339, CTK1G9150, CTK3J2699, HMS500N10, KBio1_000268, KBio2_001356, KBio2_003924, KBio2_006492, KBio3_002622, KS-00000KWP, NSC6498, MolPort-000-145-889, MolPort-000-664-275, MolPort-004-414-251, NINDS_000268, HMS1569D09, HMS1766D22, HMS1920L22, HMS2092E03, HMS2096D09, HMS2230B22, HMS3259M04, HMS3371D17, HMS3655J07, HMS3713D09, Pharmakon1600-01500515, BCP22165, HY-B0346, NSC-6498, NSC70461, Propylthiouracil (JP15/USP/INN), Propylthiouracil (JP17/USP/INN), ZINC4640636, Tox21_110882, Tox21_201741, Tox21_300280, 2-mercapto-6-propyl-pyrimidin-4-ol, ACM500505, AN-733, ANW-75636, BBL003084, BDBM50133597, CCG-39240, HTS000719, LS-158, MFCD00006041, NSC-70461, NSC757302, s1988, SBB003855, STL102645, 6-Propyl-2-sulfanyl-4-pyrimidinol #, AKOS000120319, AKOS001053246, AKOS015892537, Tox21_110882_1, 2-thio-4-hydroxy-6-n-propylpyrimidine, BS-3928, CS-2390, DB00550, MCULE-9403710688, NC00533, NSC-757302, PS-3436, RTR-036940, 4-hydroxy-6-n-propylpyrimidine-2-thiol, IDI1_000268, 6-Propyl-2-thiouracil, enzyme inhibitor, NCGC00016229-01, NCGC00016229-02, NCGC00016229-03, NCGC00016229-04, NCGC00016229-05, NCGC00016229-06, NCGC00016229-07, NCGC00016229-08, NCGC00016229-09, NCGC00016229-10, NCGC00016229-11, NCGC00016229-13, NCGC00016229-14, NCGC00090881-01, NCGC00090881-02, NCGC00090881-03, NCGC00178089-01, NCGC00178089-02, NCGC00183321-01, NCGC00254180-01, NCGC00259290-01, 2-mercapto-4-hydroxy-6-propyl pyrimidine, 6-propyl-2-sulfanyl-3H-pyrimidin-4-one, AC-10795, CC-33983, CPD000058275, KB-24812, KB-45926, propylthiouracil / 6-Propyl-2-thiouracil, SAM002554926, SC-17509, SMR003317355, SBI-0051497.P003, AB2000408, TR-036940, BB 0242498, FT-0621285, FT-0695546, P0533, ST50308196, 3052-EP2272832A1, C07569, D00562, K-9466, K-9745, L-4426, 2-THIO-4-HYDROXY-6-N-PROPYL-PYRIMIDINE, 6-Propyl-2-thiouracil, purum, >=98.0% (T), AB00052082_05, AB00052082_06, AS-871/40901436, C-24421, 6-propyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone, I03-0144, SR-05000001706-1, SR-05000001706-2, SR-05000001706-3, W-105881, 6-Propyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4 -one, BRD-K48168960-001-04-4, BRD-K48168960-001-05-1, BRD-K48168960-001-08-5, Z56922173, F1967-1318, F2199-0035, F3097-4245, T0517-6237, 4(1H)-PYRIMIDINONE,6-BUTYL-2,3-DIHYDRO-2-THIOXO-, 6-Propyl-2-thiouracil, VETRANAL(TM), analytical standard, 6-propyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one, Propylthiouracil, European Pharmacopoeia (EP) Reference Standard, Propylthiouracil, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11

ID: 1180

InChIKey: KNCOEHWBIKRZHW-UHFFFAOYSA-N
SMILES: C1(=NC=CC=C1)C1C=C(CCO)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 15458985
synonyms found at PubChem are:
SCHEMBL9902305, 3-(2-Pyridinyl)-5-isoxazoleethanol

ID: 1181

InChIKey: KNGWXFIRAISQAP-UHFFFAOYSA-N
SMILES: CC1(CCC(CC1)C(C)(C)NC(=O)CBr)NCC(COC2=CC=CC3=C2C=CN3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1239
synonyms found at PubChem are:
(+/-)-Pindobind, 106469-51-6, Pindobind-5HT1A, 2-bromo-n-[2-(4-{[2-hydroxy-3-(1h-indol-4-yloxy)propyl]amino}-4-methylcyclohexyl)propan-2-yl]acetamide, acetamide,2-bromo-n-[1-[4-[[2-hydroxy-3-(1h-indol-4-yloxy)propyl]amino]-4-methylcyclohexyl]-1-methylethyl]-, N8-Bim, 2-bromo-N-[2-[4-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-4-methylcyclohexyl]propan-2-yl]acetamide, AC1Q27GZ, Lopac0_000977, AC1L1B18, CHEMBL157881, CTK8E6744, ( inverted question mark)-Pindobind, AKOS030530991, CCG-205057, ( inverted exclamation markA)-Pindobind, N(8)-Bromoacetyl-N(1)-3'-(4-indolyloxy)-2'-hydroxypropyl-1,8-diamino-4-menthane, KB-270547, RT-014886, EU-0100977, P-119, SR-01000075283, SR-01000075283-1, 2-bromo-N-[2-[4-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino, N8-Bromoacetyl-N1-3'-(4-indolyloxy)-2'-hydroxy-propyl-[Z]-1,8-diamino-p-methane, 2-Bromo-N-[1-methyl-1-[4alpha-methyl-4-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]cyclohexan-1alpha-yl]ethyl]acetamide, Acetamide, 2-bromo-N-(1-(4-((2-hydroxy-3-(1H-indol-4-yloxy)propyl)amino)-4-methylcyclohexyl)-1-methylethyl)-, N1-Bromoacetyl-N8-3 inverted exclamation marka-(4-indolyloxy)-2 inverted exclamation marka-hydroxy-propyl-[Z]-1,8-diamino-p-menthane

ID: 1182

InChIKey: KNHUKKLJHYUCFP-UHFFFAOYSA-N
SMILES: CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2796
synonyms found at PubChem are:
clofibrate, 637-07-0, Ethyl clofibrate, Clofibratum, Clofibrato, Atromid-S, Miscleron, Atromid, Liprin, EPIB, Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, Angiokapsul, Antilipid, Antilipide, Arterioflexin, Arterosol, Ateriosan, Athebrate, Atheromide, Atheropront, Chlorphenisate, Clofibate, Lipofacton, Ticlobran, Amotril, Anparton, Ateculon, Atrolen, Atromida, Lipavil, Lipavlon, Lipomid, Liprinal, Xyduril, Apolan, Amotril S, Ethyl chlorophenoxyisobutyrate, Athranid-wirkstoff, Atromidin, Bioscleran, Cartagyl, Citiflus, Claripex, Clofibram, Clofibrat, Clofinit, Clofipront, Fibralem, Gerastop, Hyclorate, Klofibrat, Klofiran, Levatrom, Lipidsenker, Liponorm, Liporeduct, Lobetrin, Normalip, Persantinat, Regardin, Serotinex, Skleromexe, Atrovis, Azionyl, Bresit, Clobrat, Clofar, Delipid, Deliva, Lipamid, Liporil, Liposid, Normat, Regelan, Sklero, Dura clofibrat, Sklero-Tablinen, neo-Atomid, Neo-Atromid, Atromid S, Claripex CPIB, Clobren-SF, CPIB, ELPI, Cinnarizin, Cloberat, Misclerone, Normolipol, Robigram, Skerolip, Artevil, Negalip, Normet, Recolip, Scrobin, Yoclo, Sklero-tabuls, 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester, Regelan N, Lipide 500, Chlorfenisate, Oxan 600, Artes, Ethyl 2-(p-chlorophenoxy)isobutyrate, 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester, Ethyl para-chlorophenoxyisobutyrate, Sklerepmexe, Miskleron, Serofinex, Sklerolip, Skleromex, Clofibrato [Spanish], Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, Sklero-tablinene, NSC-79389, Ethyl p-chlorophenoxyisobutyrate, Clobren-5F, Vincamin compositum, Clofibratum [INN-Latin], Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester, Clofibrato [INN-Spanish], AY 61123, AY-61123, alpha-p-Chlorophenoxyisobutyryl ethyl ester, ICI 28257, Ethyl 2-(4-chlorophenoxy)isobutyrate, Novofibrate, Abitrate, alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester, UNII-HPN91K7FU3, Clofibric Acid, Ethyl Ester, Ethyl 2-(p-chlorophenoxy)-2-methylpropionate, C12H15ClO3, CCRIS 177, clofibrate (CLOF), Ethyl-alpha-p-chlorophenoxy-isobutyrate, Ethyl alpha-(4-chlorophenoxy)isobutyrate, Ethyl alpha-(p-chlorophenoxy)isobutyrate, HSDB 3038, Clofibrate [USAN:INN:BAN:JAN], 19 more names available, EINECS 211-277-4, ATROMID-S (TN), ICI-28257, NSC 79389, CHEMBL565, BRN 1913459, HPN91K7FU3, Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl ester, BML2-F02, CHEBI:3750, Propanoic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester, Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester, Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester, .alpha.-p-Chlorophenoxyisobutyryl ethyl ester, KNHUKKLJHYUCFP-UHFFFAOYSA-N, NSC79389, Ethyl alpha-(4-chlorophenoxy)-alpha-methylpropionate, Ethyl alpha-(p-Chlorophenoxy)-alpha-methylpropionate, Ethyl alpha-p-chlorophenoxyisobutyrate, .alpha.-(p-Chlorophenoxy)isobutyric acid, ethyl ester, Isobutyric acid, alpha-(p-chlorophenoxy)-, ethyl ester, Ethyl 2-(para-chlorophenoxy)-2-methylpropionate (IUPAC), NCGC00015257-08, p-Chlorophenoxyisobutyric acid ethyl ester, Ethyl .alpha.-(4-chlorophenoxy)isobutyrate, Ethyl .alpha.-(p-chlorophenoxy)isobutyrate, DSSTox_CID_336, C 6643, ethyl 2-(4-chlorophenoxy)-2-methyl-propanoate, 2-(4-Chlorophenoxy)isobutyric Acid Ethyl Ester, DSSTox_RID_75521, DSSTox_GSID_20336, ethyl 2-[(4-chlorophenyl)oxy]-2-methylpropanoate, 2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester, Ethyl .alpha.-(p-chlorophenoxy)-.alpha.-methylpropionate, Ethyl .alpha.-(4-chlorophenoxy)-.alpha.-methylpropionate, Athromidin, CAS-637-07-0, SMR000058279, SR-01000075544, Chlorophenoxyisobutyrate, Ethyl, Clofibrate liquid, Clobren SF, Clofibrate, liquid, Clofibrate [USAN:USP:INN:BAN:JAN], Atromid-S, Clofibrate, Spectrum_001735, AC1L1EHK, Spectrum2_001209, Spectrum4_000223, Spectrum5_001133, Lopac-C-6643, D0J5DC, UPCMLD-DP019, SCHEMBL2356, NCIOpen2_004739, BIDD:PXR0178, CBiol_001860, Lopac0_000306, BSPBio_001577, KBioGR_000297, KBioGR_000885, KBioSS_000297, KBioSS_002215, KSC492E2B, MLS001336011, MLS001336012, MLS002153494, BIDD:GT0172, DivK1c_000822, DivK1c_000926, SPBio_000998, Clofibrate (JP15/USP/INN), Clofibrate (JP17/USP/INN), GTPL2667, DTXSID3020336, UPCMLD-DP019:001, BCBcMAP01_000104, CTK3J2220, HMS502J04, HMS502O08, KBio1_000822, KBio1_000926, KBio2_000297, KBio2_002215, KBio2_002865, KBio2_004783, KBio2_005433, KBio2_007351, KBio3_000593, KBio3_000594, WLN: GR DOX1&1&VO2, ZINC56648, Clofibrate, >=98.0% (GC), MolPort-000-145-477, NINDS_000822, NINDS_000926, Bio1_000146, Bio1_000635, Bio1_001124, Bio2_000297, Bio2_000777, HMS1361O19, HMS1791O19, HMS1989O19, HMS2089P03, HMS2093G07, HMS2233C17, HMS3260N14, HMS3373C06, HMS3402O19, HMS3715J03, Pharmakon1600-01503429, AC1Q3200, EBD52899, HY-B0287, ZX-AT020414, Tox21_110116, Tox21_202414, Tox21_300277, Tox21_500306, ANW-42230, BDBM50085047, BG0148, CCG-40281, MFCD00000615, NSC758474, SBB099633, AKOS015889383, Tox21_110116_1, API0025998, CS-2300, DB00636, LP00306, LS-7282, MCULE-9236719628, NE29896, NSC-758474, OR26850, RTR-021904, Clofibrate (Clofibric acid ethyl ester), IDI1_000822, IDI1_000926, IDI1_034047, KS-00000X36, Clofibrate, analytical reference material, NCGC00015257-01, NCGC00015257-02, NCGC00015257-03, NCGC00015257-04, NCGC00015257-05, NCGC00015257-06, NCGC00015257-07, NCGC00015257-09, NCGC00015257-10, NCGC00015257-11, NCGC00015257-12, NCGC00015257-14, NCGC00093755-01, NCGC00093755-03, NCGC00093755-04, NCGC00093755-05, NCGC00093755-06, NCGC00093755-07, NCGC00093755-08, NCGC00254073-01, NCGC00259963-01, NCGC00260991-01, AN-20436, AS-14127, CC-05772, CJ-00382, DA-42739, K009, NCI60_041748, tetrahydro-2-Furanmethanesulfonyl chloride, ZB001758, Ethyl .alpha.-p-(chlorophenoxy)isobutyrate, SBI-0050294.P003, AB0013973, AB2000309, DB-054528, KB-111557, KB-162888, KB-224318, TL8004467, TR-021904, EU-0100306, FT-0625865, ST50319977, 2-(p-Chlorophenoxy)isobutyric acid ethyl ester, C06916, D00279, EN300-119182, AB00052358-07, AB00052358-08, AB00052358_09, AB00052358_10, Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate #, A834483, C-14662, ethyl 2-(4-chloranylphenoxy)-2-methyl-propanoate, Acetic acid, (p-chlorophenoxy)dimethyl-, ethyl este, Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, 99%, I01-1842, SR-01000075544-1, SR-01000075544-4, SR-01000075544-5, SR-01000075544-8, Z53835984, 2-(p-chlorophenoxy)-2-methylPropanoic acid ethyl ester, 2-(p-chlorophenoxy)-2-methylpropionic acid ethyl ester;, 2-(4-Chloro-phenoxy)-2-methyl-propionic acid ethyl ester, Clofibrate, European Pharmacopoeia (EP) Reference Standard, Isobutyric acid, .alpha.-(p-chlorophenoxy)-, ethyl ester, Clofibrate, United States Pharmacopeia (USP) Reference Standard

ID: 1183

InChIKey: KNKVJBRMGKXDGO-UHFFFAOYSA-N
SMILES: C=CCCCCCCCCCCCC1=CC=CO1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6857792
synonyms found at PubChem are:
AVOCADENOFURAN, SDCCGMLS-0066904.P001, 2-tridec-12-enylfuran, AC1OAH7K, 2-(trideca-12-enyl)furan, SPECTRUM1505807, SCHEMBL2606224, CHEMBL1608830, CTK8H8434, CCG-214476, 2-(TRIDEC-12-EN-1-YL)FURAN, NCGC00095829-01, 25346-24-1, SR-05000002495, SR-05000002495-1

ID: 1184

InChIKey: KNURFLJTOUGOOQ-UHFFFAOYSA-N
SMILES: CC(=O)NNC(=O)N1CC2=CC=CC=C2OC3=C1C=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4336830
synonyms found at PubChem are:
SC 19220, 19395-87-0, SC-19220, SC19220, 2-Acetylhydrazide 10(11H)-carboxylic acid, KNURFLJTOUGOOQ-UHFFFAOYSA-N, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, SR-01000076128, Tocris-1206, Lopac-S-3065, D0OA8M, AC1N81PQ, Lopac0_001097, MLS000862188, CHEMBL112816, GTPL1922, SCHEMBL12648484, BDBM85341, CHEBI:92916, CTK8G3065, MolPort-003-959-528, HMS2231G10, HMS3263K16, HMS3267B11, HMS3370E15, ZINC2392218, Tox21_501097, MFCD02259329, AKOS024456464, CCG-205174, LP01097, CAS_4336830, NSC_4336830, NCGC00015943-01, NCGC00015943-02, NCGC00015943-03, NCGC00015943-04, NCGC00015943-05, NCGC00025038-01, NCGC00025038-02, NCGC00025038-03, NCGC00261782-01, SMR000326951, B6633, EU-0101097, SC 19220, >=98% (HPLC), solid, S 3065, L024046, J-012559, SR-01000076128-2, SR-01000076128-3, BRD-K52512893-001-03-0, N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide, N'-acetyl-3-chloro-6H-benzo[b][1,5]benzoxazepine-5-carbohydrazide, 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxy-(2-acetyl)hydrazide, 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-acetylhydrazide

ID: 1185

InChIKey: KNZADIMHVBBPOA-UHFFFAOYSA-N
SMILES: CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68304
synonyms found at PubChem are:
Dyclonine hydrochloride, 536-43-6, Dyclonine HCL, Dyclone, Dyclothane, Tanaclone, 4'-Butoxy-3-piperidinopropiophenone hydrochloride, Dyclocaine hydrochloride, Dyclonine (hydrochloride), UNII-ZEC193879Q, P-267, EINECS 208-633-6, NSC 23018, 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride, C18H28ClNO2, Dyclonine hydrochloride [USP], MLS000069532, S 154, C 5422, ZEC193879Q, Piperidine, 1-(2-(4-butoxybenzoyl)ethyl), hydrochloride, SMR000038382, 4-n-Butoxy-beta-(1-piperidyl)propiophenone hydrochloride, DSSTox_CID_25323, DSSTox_RID_80802, DSSTox_GSID_45323, Dyclonine hydrochloride (USP), W-105718, Propiophenone, 4'-butoxy-3-piperidino-, hydrochloride, WLN: T6NTJ A2VR DO4 &GH, CHEBI:4725, NCGC00016498-01, CAS-536-43-6, 1-(4-butoxyphenyl)-3-piperidylpropan-1-one, chloride, 4-n-Butoxy-.beta.-(1-piperidyl)propiophenone hydrochloride, 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride, SR-01000000032, Prestwick_674, Dyclone (TN), Dyclonine hydrochlori, Dyclonine, Hydrochloride, Sulfourea; Thiocarbamide, AC1Q3DUL, Opera_ID_1265, AC1L29GY, MLS001077359, MLS002222240, SCHEMBL317219, SPECTRUM1500268, 586-60-7 (Parent), CHEMBL1200478, DTXSID6045323, CTK8F9398, HY-B0364A, KNZADIMHVBBPOA-UHFFFAOYSA-N, MolPort-003-666-173, HMS1568F10, HMS1920K06, Pharmakon1600-01500268, BCP28402, KS-00000G4E, NSC23018, NSC25588, Tox21_110459, CCG-40231, NSC-23018, NSC-25588, NSC756745, s2041, SBB058147, AKOS015951364, Tox21_110459_1, AC-8346, ACN-025344, AN-8074, API0008891, CS-2421, DS-3341, NSC-756745, NCGC00016498-08, NCGC00094662-01, NCGC00094662-02, NCGC00094662-03, NCGC00094662-04, BC204343, SC-46932, ST086519, AB0018094, AB1009570, LS-125086, D4303, FT-0625635, D00735, SR-01000000032-4, 1-(4-butoxyphenyl)-3-(1-piperidyl)propan-1-one hydrochloride, 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one hydrochloride, 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone hydrochloride, 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (9CI), 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1), Dyclonine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Dyclonine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, AC1LCWFJ, AKOS015915394, I14-6100, 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one; hydron; chloride, 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride (1:1), 1-[3-(4-butoxyphenyl)-3-oxopropyl]piperidinium chloride, 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride, MolPort-000-721-661, MCULE-3987805129

ID: 1186

InChIKey: KORXYHAXZMUWOH-UHFFFAOYSA-N
SMILES: C1C2C(C(=O)N)=C(NC(CCCCC)=O)SC=2CCC1

biological descriptors:

reference list:

"K Du" "AS Verkman" "H Yang" "T Ma" "N Pedemonte" "GL Lukacs" "VS Gopinath" "AA Shelat" "A Taddei" "C Folli" "LJ Galietta" "RK Guy"

CID is 4348538
synonyms found at PubChem are:
AC1N8RQ6, SCHEMBL3125764, AKOS000291773, SR-01000089348, SR-01000089348-1, 2-(hexanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

ID: 1187

InChIKey: KPHWPUGNDIVLNH-UHFFFAOYSA-M
SMILES: C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 27194
synonyms found at PubChem are:
Diclofenac sodium, 15307-79-6, Sodium diclofenac, Diclofenac sodium salt, Voltaren, Solaraze, Anthraxiton, Prophenatin, Allvoran, Batafil, Delimon, Delphimix, Dichronic, Feloran, Kriplex, Neriodin, Orthophen, Ortofen, Tsudohmin, Valetan, Voltarene, Vonafec, Blesin, Urigon, Vurdon, Diclophenac sodium, Voltaren ophthalmic, Diclofenac (Sodium), Voltaren-XR, C14H10Cl2NNaO2, Assaren, Dyloject, Olfen, UNII-QTG126297Q, CCRIS 1909, GP 45840, Sodium (o-(2,6-dichloroanilino)phenyl)acetate, EINECS 239-346-4, Ba 47210, Sodium (o-((2,6-dichlorophenyl)amino)phenyl)acetate, sodium {2-[(2,6-dichlorophenyl)amino]phenyl}acetate, (o-(2,6-Dichloroanilino)phenyl)acetic acid sodium salt, MLS000028386, CHEBI:4509, (o-(2,6-Dichloroanilino)phenyl)acetic acid monosodium salt, 2-((2,6-Dichlorophenyl)amino)benzeneacetic acid monosodium salt, Sodium (o-(2,6-dichloroanilino)phenyl) acetate, QTG126297Q, sodium 2-[2-(2,6-dichloroanilino)phenyl]acetate, Benfofen, Ecofenac, IN1491, NCGC00017082-02, 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt, SMR000058567, Solaraze (TN), CAS-15307-79-6, Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, monosodium salt, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, monosodium salt, DSSTox_CID_17208, DSSTox_RID_79308, DSSTox_GSID_37208, Q-200965, 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid, Na, Sodium (2-((2,6-dichlorophenyl)amino)phenyl)acetate, sodium 2-(2-((2,6-dichlorophenyl)amino)phenyl)acetate, Abitren, Acetic acid, o-(2,6-dichloroanilino)phenyl-, monosodium salt, 2-[(2,6-Dichlorophenyl)amino]-benzeneacetic acid monosodium salt, Voltaren Gel, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, monosodium salt [CAS], SMR000449318, sodium;2-[2-(2,6-dichloroanilino)phenyl]acetate, GP-45840, Diclofenac sodium injection, Sodium 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetate, sodium 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetate, Diclofenac sodium topical gel, Berifen, DIC075V, Diclofenac sod, Diclofenac sodium [USAN:JAN], sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate, TDS 943, Voltaren (TN), Diclofenac sodium [USAN:USP:JAN], sodium diclofenac(1-), Diclofenac Sodium,(S), Opera_ID_564, SODIUM DICHLOFENAC, AC1NMYU1, Lopac-D-6899, potassium diclofenac(1-), EC 239-346-4, AC1Q1V6Y, CHEMBL1034, SCHEMBL24009, MLS000758255, MLS001148587, MLS001423970, MLS002222163, MLS003882590, ARONIS24305, SPECTRUM1500237, Diclofenac sodium (JP17/USP), DTXSID3037208, HMS500N14, KS-00000KCZ, BBC/461, KPHWPUGNDIVLNH-UHFFFAOYSA-M, MolPort-000-699-119, REGID_for_CID_5018304, HMS1569H10, HMS1920E16, HMS2051M05, HMS2091M06, HMS2096H10, HMS2235O06, HMS2236D03, HMS3261I04, HMS3369K11, HMS3371J05, HMS3393M05, HMS3650B13, HMS3655A22, HMS3713H10, KUC112363N, BCP02915, KS-000048IF, ZX-AS004665, Tox21_110770, Tox21_300265, Tox21_500441, BG0165, CCG-39754, GP9539, MFCD00082251, s1903, SBB032269, STK400073, AKOS000310014, AKOS005267222, AKOS024278942, Tox21_110770_1, AC-1487, API0002325, BCP9000605, CCG-100765, CS-2355, KS-5038, LP00441, MCULE-3279769301, NC00015, RL01959, KSC-322-017, NCGC00015361-01, NCGC00015361-02, NCGC00015361-03, NCGC00015361-04, NCGC00017082-01, NCGC00017082-03, NCGC00021125-03, NCGC00093858-01, NCGC00093858-02, NCGC00094648-01, NCGC00094648-02, NCGC00253928-01, NCGC00261126-01, AN-14916, BC201631, CPD000058567, CPD000449318, H867, HY-15037, LS-11576, SAM001247057, SC-25991, ST024738, BCP0726000303, AB0013319, AB1009344, B1457, D2508, EU-0100441, FT-0624732, Sodium 2-(2,6-Dichloroanilino)phenylacetate, sodium 2-(2,6-dichloroanilino)-phenylacetate, BIM-0051341.0001, D 6899, D00904, K-4848, A809387, I06-162, sodium 2-[(2,6-dichlorophenyl)amino]phenylacetate, I06-0162, sodium 2-[(2,6-dichlorophenyl)-amino]phenylacetate, 2-(2,6-Dichloroanilino)phenylacetic Acid Sodium Salt, sodium 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetate, sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate, 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium, Diclofenac Sodium 1.0 mg/ml in Methanol (as free acid), 2-(2,6-DICHLOROANILINO)PHENYLACETIC ACID SODIUM SA, sodium 2-[2-[[2,6-bis(chloranyl)phenyl]amino]phenyl]ethanoate, 1147187-62-9

ID: 1188

InChIKey: KPMKNHGAPDCYLP-UHFFFAOYSA-N
SMILES: CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 91657
synonyms found at PubChem are:
Nimustine hydrochloride, 55661-38-6, ACNU, Nimustine HCl, Nidran, Nidran hydrochloride, Nimustina clorhidrato, CS 439 HCl, UNII-DFR965WKBU, Nimustina clorhidrato [Spanish], CS-439, DFR965WKBU, NSC-245,382, Nimustine hydrochloride [JAN], CHEBI:7576, 52208-23-8, 1-(2-Cloroetil)-1-nitroso-3-((2-metil-4-aminopirimidin-5-il)metil)urea clorhidrato [Spanish], 1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 1-(4-Amino-2-methylpyrimidine-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride, N'-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitrosourea HCl, N'-((4-Amino-2-metil-5-pirimidinil)metil)-N-(2-cloroetil)-N-nitrosourea clorhidrato [Spanish], Nimustine hydrochloride (JAN), 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea Hydrochloride, Urea, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitroso-, monohydrochloride, 3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-1-(2-chloroethyl)-1-nitrosourea hydrochloride, 3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitroso-urea hydrochloride, Nidran (TN), Nimustinehydrochloride, Nimustine HCl(ACNU), 1-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-3-(2-chloroethyl)-3-nitrosourea, AC1L3MIP, nimustine monohydrochloride, AC1Q3BJ6, SCHEMBL98303, C9H14Cl2N6O2, MLS002153238, Nimustine hydrochloride, solid, CHEMBL1256616, CTK8B3371, DTXSID80204185, MolPort-003-986-952, ANW-42405, MFCD01676942, NSC245382, AKOS015895226, MCULE-2422791904, NSC-245382, 1-(2-Cloroetil)-1-nitroso-3-((2-metil-4-aminopirimidin-5-il)metil)urea clorhidrato, N'-((4-Amino-2-metil-5-pirimidinil)metil)-N-(2-cloroetil)-N-nitrosourea clorhidrato, AC-15840, AN-40356, CC-32863, SC-46523, SMR001230702, WLN: T6N CNJ B1 DZ E1MVNNO&2G, LS-158850, TL8003631, TR-019617, FT-0083536, FT-0630684, N0821, C11276, D01059, 208N238, A825909, A828980, A830740, C-19176, I06-0232, 1-(4-AMINO-2-METHYL-5-PYRIMIDINYL)-METHYL-3-(2-CHL, 1-(4-Amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitroso-urea hydrochloride, N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride, Urea, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitroso-, N inverted exclamation marka-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride, Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-, monohydrochloride, Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-, monohydrochloride (9CI)

ID: 1189

InChIKey: KPQZUUQMTUIKBP-UHFFFAOYSA-N
SMILES: CC1=NC=C(N1CC(C)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 71815
synonyms found at PubChem are:
Secnidazole, 3366-95-8, Secnidazol, Flagentyl, Secnidazolum, Secnidazolum [INN-Latin], Solosec, RP 14539, Secnidazol [INN-Spanish], PM 185184, 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol, 1-(2-Methyl-5-nitro-1-imidazolyl)-2-propanol, Secnidazole (Flagentyl), SYM-1219, EINECS 222-134-0, alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol, 1-(2-Methyl-5-nitro-imidazol-1-yl)-propan-2-ol, MLS000559043, PM-185184, 1-(2-Hydroxypropyl)-2-methyl-5-nitroimidazol, NCGC00095158-01, RP-14539, SMR000149359, alpha,2-Dimethyl-5-nitroimidazole-1-ethanol, 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol, Imidazole-1-ethanol, alpha,2-dimethyl-5-nitro-, Secnidazole hemihydrate, DSSTox_CID_25934, DSSTox_RID_81233, DSSTox_GSID_45934, CAS-3366-95-8, SR-01000685111, seknidazol, Sindose, Secnil, Secnidazole [INN:BAN:DCF], Secnidal (TN), Secnidazole [USAN:INN:BAN:DCF], SYM 1219, Solosec (TN), AC1L2GUM, Opera_ID_1811, Spectrum2_000033, Spectrum3_001956, Secnidazole (USAN/INN), D0V5IW, 1-(2-Methyl-5-nitroimidazol-1-yl)-2-propanol, BSPBio_003556, MLS000759496, MLS001201813, MLS001424126, MLS006011434, SCHEMBL363924, SPECTRUM1505304, SPBio_000125, CHEMBL498847, DTXSID3045934, CHEBI:94433, CTK8B3024, KBio3_002874, CHEBI:140628, MolPort-000-811-111, HMS1922B12, HMS2051C20, HMS2090N15, HMS2231G11, HMS3369N08, HMS3393C20, HMS3656G14, HMS3714I05, Pharmakon1600-01505304, AC1Q2098, BB_SC-02113, BCP12459, HY-B1118, KS-00000H1U, Tox21_111457, ANW-41634, BBL010784, BDBM50349330, CCG-39993, FCH842433, NSC759812, STK590474, AKOS005512552, AKOS025149490, Tox21_111457_1, API0007056, CCG-100896, CS-4641, DB12834, KS-1191, MCULE-8220679702, NC00146, NSC-759812, VA11736, NCGC00095158-02, NCGC00095158-03, NCGC00095158-04, NCGC00095158-05, AC-12065, AK163575, CPD000149359, H737, SAM001246716, SC-50820, SBI-0207037.P001, 14,539 RP, AB0013222, AB1004868, DB-000688, LS-174427, FT-0601624, S0911, S2537, D07353, J10074, M-2516, PM 185184; RP 14539; Sindose; Secnil, 1-(2- hydroxypropyl)-2-methyl-5-nitroimidazole, 1H-Imidazole-1-ethanol, a,2-dimethyl-5-nitro-, AB00456738-13, AB00456738-15, AB00456738_16, AB00456738_17, PM 185184, RP 14539, 1-(2'-hydroxypropyl)-2-methyl-5- nitroimidazole, 1-(2-methyl-5-nitro-imidazol-1-yl)propan-2-ol, 366S958, A821901, I06-0707, J-019291, SR-01000685111-4, SR-01000685111-6, SR-01000685111-7, (RS)-1-(2-Methyl-5-nitro-1-imidazolyl)-2-propanol, BRD-A70083328-001-02-9, BRD-A70083328-001-12-8, 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2- ol

ID: 1190

InChIKey: KPSRODZRAIWAKH-UHFFFAOYSA-N
SMILES: CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2763
synonyms found at PubChem are:
Ciprofibrate, 52214-84-3, Lipanor, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid, Ciprofibratum, Ciprofibrato, Modalim, Oroxadin, 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, Ciprofibratum [INN-Latin], Ciprofibrato [INN-Spanish], Hiperlipen, Ciprol, Win-35833, WIN 35833, CCRIS 173, C13H14Cl2O3, Ciprofibrate [USAN:BAN:INN], Win 35,833, EINECS 257-744-6, Ciprofibrate (USAN/INN), BRN 1984981, 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid, 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid, CHEBI:50867, KPSRODZRAIWAKH-UHFFFAOYSA-N, Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-, NCGC00164447-01, 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, 2-{[4-(2,2-dichlorocyclopropyl)phenyl]oxy}-2-methylpropanoic acid, DSSTox_CID_331, Propanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-, C 0330, DSSTox_RID_75519, DSSTox_GSID_20331, Hyperlipen, 2-{4-[2,2-dichlorocyclopropyl]phenoxy}-2-methylpropanoic acid, SMR000857190, SR-01000075734, 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic acid, Ciprofibrate?, Ciprofibrate [USAN:INN:BAN], CAS-52214-84-3, AC1L1EET, Prestwick0_001076, Prestwick1_001076, Prestwick2_001076, Prestwick3_001076, D0EJ6O, Lopac0_000168, SCHEMBL26870, BSPBio_001092, MLS002154143, MLS006011758, SPBio_002996, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]isobutyric acid, BPBio1_001202, CHEMBL557555, GTPL3438, DTXSID8020331, CTK7I5107, KS-00000FXC, AOB6803, MolPort-003-666-795, BCPP000277, HMS1571G14, HMS2098G14, HMS2235J14, HMS3260B17, HMS3369B22, HMS3656P09, HMS3715G14, Pharmakon1600-01502008, BCP03728, EBD38709, HY-B0664, Tox21_112121, Tox21_201359, Tox21_302840, Tox21_500168, AN-880, ANW-46062, BBL010821, BDBM50371235, BG0457, MFCD00467135, NSC759617, s2665, Sanofi Winthrop brand of ciprofibrate, STK624758, AKOS005557843, Tox21_112121_1, AC-1018, API0002026, BCP9000533, CCG-204263, CS-2898, KS-1201, LP00168, LS-7279, MCULE-8060052925, NSC-759617, RP29995, Sanofi Synthelabo brand of ciprofibrate, NCGC00015202-02, NCGC00015202-03, NCGC00015202-04, NCGC00015202-05, NCGC00015202-06, NCGC00015202-08, NCGC00093652-01, NCGC00093652-02, NCGC00256361-01, NCGC00258911-01, NCGC00260853-01, 4CA-0385, AK-77509, BC207557, CC-25814, BCP0726000148, AB0010540, AB2000704, AX8121411, KB-222047, RT-004891, AB00514032, EU-0100168, FT-0602946, ST24027521, D03521, AB00514032_06, 214C843, A828985, C-18160, I14-0695, J-520054, SR-01000075734-1, SR-01000075734-4, SR-01000075734-7, BRD-A49358627-001-03-9, BRD-A49358627-001-10-4, 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid, Ciprofibrate, European Pharmacopoeia (EP) Reference Standard, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-propanoic acid, Propionic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-, 2-[4-[2,2-bis(chloranyl)cyclopropyl]phenoxy]-2-methyl-propanoic acid, Ciprofibrate for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 1191

InChIKey: KPXIBWGPZSPABK-FXAWDEMLSA-N
SMILES: CC(C)C1=C(C2=C(C=C1)[C@]3(CCC4=C([C@@H]3CC2)COC4=O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 173273
synonyms found at PubChem are:
Triptophenolide, 74285-86-2, Tryptophenolide, Triptohenolide, Hypolide, (-)-triptophenolide, Spectrum_001722, SpecPlus_000566, Spectrum2_001618, Spectrum3_001928, Spectrum4_001660, Spectrum5_000539, Hypolide (Triptophenolide), AC1L59XA, BSPBio_003528, KBioGR_002159, KBioSS_002202, DivK1c_006662, SPECTRUM1504005, SPBio_001655, CHEMBL3039217, SCHEMBL19236270, KBio1_001606, KBio2_002202, KBio2_004770, KBio2_007338, KBio3_002756, CHEBI:114185, MolPort-003-665-784, BCP26008, HY-N0475, ZINC2558155, BDBM50199857, CCG-38739, AKOS015897179, CS-3764, SDCCGMLS-0066775.P001, N2059, 285T862, SR-05000002569, I07-0312, SR-05000002569-1, BRD-K73210450-001-02-3, BRD-K73210450-001-03-1, (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one, Phenanthro(1,2-c)furan-1(3H)-one, 3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR-trans)-, Phenanthro[1,2-c]furan-1(3H)-one,3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR,9bS)-

ID: 1192

InChIKey: KPYPLDPMBWPEBO-BTJKTKAUSA-N
SMILES: CC(C)OC1=C(N=CC=C1)N(C)C2CCN(CC2)CC3=CC=CC=C3.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957730
synonyms found at PubChem are:
U-101958 maleate, U-101958 maleate salt, CHEMBL64119, EU-0101276, U-101958 maleate salt, solid, HMS3263P14, Tox21_501276, CCG-222580, LP01276, NCGC00094512-01, NCGC00261961-01, U-115, SR-01000075412, SR-01000075412-1, 1-Benzyl-4-aminomethyl-N-[(3'-isopropoxy)-2'-pyridinyl]piperidine maleate, 1-Benzyl-4-aminomethyl-N-[(3 inverted exclamation marka-isopropoxy)-2 inverted exclamation marka-pyridyl]piperidine maleate salt

ID: 1193

InChIKey: KPYSYYIEGFHWSV-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(CC(=O)O)CN)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2284
synonyms found at PubChem are:
baclofen, 1134-47-0, Lioresal, 4-Amino-3-(4-chlorophenyl)butanoic acid, Baclon, DL-Baclofen, Kemstro, Gabalon, Baclofene, Baclofeno, Baclofenum, Baclophen, Lioresal Intrathecal, Atrofen, (+-)-Baclofen, Apo-Baclofen, (RS)-BACLOFEN, 4-Amino-3-(4-chlorophenyl)butyric acid, beta-(4-Chlorophenyl)gaba, Clofen, Ciba 34,647-Ba, C 34647Ba, Pms-Baclofen, (+/-)-BACLOFEN, beta-(Aminomethyl)-4-chlorobenzenepropanoic acid, Ba-34647, Baclofene [INN-French], Baclofenum [INN-Latin], Chlorophenyl GABA, Baclofeno [INN-Spanish], Baclofen (R,S), DL-4-Amino-3-p-chlorophenylbutanoic acid, Ba 34647, PCP-GABA, beta-(Aminomethyl)-p-chlorohydrocinnamic acid, beta-(p-Chlorophenyl)-gamma-aminobutyric acid, Nu-Baclofen, gamma-Amino-beta-(p-chlorophenyl)butyric acid, Lioresal (TN), Kemstro (TN), Ba-34,647, CCRIS 3722, Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, Baclofen [USAN:INN:BAN:JAN], CIBA-34,647-BA, Butanoic acid, 4-amino-3-(4-chlorophenyl)-, 4-AMINO-3(4-CHLOROPHENYL)BUTYRIC ACID, EINECS 214-486-9, CHEMBL701, BRN 2104494, C10H12ClNO2, CHEBI:2972, KPYSYYIEGFHWSV-UHFFFAOYSA-N, (+/-)-beta-(Aminoethyl)-4-chlorobenzenepropanoic acid, Benzenepropanoic acid, .beta.-(aminomethyl)-4-chloro-, (+/-)-beta-(Aminomethyl)-4-chlorobenzenepropanoic acid, NCGC00015156-11, (RS)-Amino-3-(4-chlorophenyl)butyric acid, DSSTox_CID_2641, B 5399, DSSTox_RID_76670, DSSTox_GSID_22641, .beta.-(Aminomethyl)-4-chlorobenzenepropanoic acid, HYDROCINNAMIC ACID, beta-(AMINOMETHYL)-p-CHLORO-, Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-(9CI), Baclospas, Gablofen, Genpharm, ApoBaclofen, BaclofeneIrex, GenBaclofen, Lebic, NuBaclo, Baclofene Irex, Baclofene-Irex, PMSBaclofen, Apo Baclofen, Gen Baclofen, Gen-Baclofen, Baclofen AWD, Nu Baclo, Nu-Baclo, PMS Baclofen, AWD, Baclofen, GABA, Chlorophenyl, SR-01000000107, baclofen o, CIBA34,647BA, IPX056, RS-Bacolfen, Lioresal, Liofen, IPX 056, (y)-Baclofen, Prestwick_85, Ba34647, Baclofen Irex Brand, Baclofen Isis Brand, CAS-1134-47-0, (?)-Baclofen, Ba34,647, Baclofen [USAN:USP:INN:BAN:JAN], Baclofen Apotex Brand, Baclofen Athena Brand, (A+/-)-Baclofen, Baclofen Novartis Brand, Irex Brand of Baclofen, Isis Brand of Baclofen, Spectrum_000066, Baclofen Ashbourne Brand, Baclofen Medtronic Brand, Baclofen Nu-Pharm Brand, Apotex Brand of Baclofen, Athena Brand of Baclofen, (.+/-.)-Baclofen, (.+/-.)-Baklofen, Baclofen Alphapharm Brand, Prestwick0_000085, Prestwick1_000085, Prestwick2_000085, Prestwick3_000085, Spectrum2_000092, Spectrum3_000310, Spectrum4_000245, Spectrum5_000852, BACLOFEN (RS)-, Baclofen Ciba-Geigy Brand, Biomol-NT_000251, D01AJY, Novartis Brand of Baclofen, UPCMLD-DP142, (±)-Baclofen, AC1L1DC6, Ashbourne Brand of Baclofen, Medtronic Brand of Baclofen, Nu Pharm Brand of Baclofen, Nu-Pharm Brand of Baclofen, Baclofen Pharmascience Brand, Alphapharm Brand of Baclofen, Lopac0_000163, Oprea1_440627, SCHEMBL19333, BSPBio_000010, BSPBio_001880, KBioGR_000650, KBioSS_000466, Ciba Geigy Brand of Baclofen, Ciba-Geigy Brand of Baclofen, MLS000028480, .beta.-(4-Chlorophenyl)gaba, DivK1c_000001, SPECTRUM1500135, Baclofen (JP15/USP/INN), Baclofen (JP17/USP/INN), Hydrocinnamic acid, .beta.-(aminomethyl)-p-chloro-, SPBio_000044, SPBio_001949, ASTA Medica Brand of Baclofen, BPBio1_000012, BPBio1_000750, GTPL1084, Pharmascience Brand of Baclofen, DTXSID5022641, UPCMLD-DP142:001, BDBM24182, CTK2F7435, HMS500A03, KBio1_000001, KBio2_000466, KBio2_003034, KBio2_005602, KBio3_001380, KS-00000VAF, AOB5950, Baclofen 0.5 mg/ml in Methanol, (inverted question mark)-Baclofen, MolPort-002-051-370, NINDS_000001, HMS1568A12, HMS1920E21, HMS2091M03, HMS2095A12, HMS3260B07, HMS3712A12, Pharmakon1600-01500135, ( inverted question mark)-Baclofen, 4-Amino-3-(4-chlorophenyl)butyri, ALBB-014712, BCP11844, BETA-(4-CHLOROPHENYL)-GABA, EX-A1378, HY-B0007, ZX-AN013424, Tox21_110090, Tox21_500163, BBL010735, BG0101, CCG-38910, CX1358, IN2071, MFCD00055143, NSC329137, NSC755906, STK535284, AKOS005174692, Tox21_110090_1, AC-4530, API0001581, CS-2990, DB00181, HS-1001, LP00163, MB00475, MCULE-2275748923, NSC-329137, NSC-755906, 4-Amino-3-(p-chlorophenyl)butyric acid, IDI1_000001, SMP1_000036, ( inverted exclamation markA)-BACLOFEN, NCGC00015156-04, NCGC00015156-05, NCGC00015156-06, NCGC00015156-07, NCGC00015156-08, NCGC00015156-12, NCGC00015156-13, NCGC00015156-15, NCGC00023843-03, NCGC00024579-03, NCGC00024579-04, NCGC00024579-05, NCGC00024579-06, NCGC00260848-01, 62594-36-9, AN-11875, BBV-40195932, BC208286, CC-17750, CPD000058294, KB-74838, LS-77134, SAM002564194, SC-19053, SMR000058294, ST075584, SBI-0050151.P004, AB0012560, (+/-)-Baclofen, >=98% (TLC), solid, 4-Amino-3-(4-chlorophenyl)butanoic acid #, AB00051921, EU-0100163, FT-0622547, (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid, .beta.-(Aminomethyl)-p-chlorohydrocinnamic acid, D00241, EN300-118715, J10366, M-2046, 4-Amino-3-(4-chlorophenyl)butyricAcid,Baclofen, AB00051921_16, .beta.-(p-Chlorophenyl)-.gamma.-aminobutyric acid, .gamma.-Amino-.beta.-(p-chlorophenyl)butyric acid, 134B470, C-11285, L000002, I01-1934, J-002965, SR-01000000107-2, SR-01000000107-4, SR-01000000107-6, SR-01000000107-8, BRD-A84174873-001-05-2, (+/- )-beta-(Aminomethyl)-4-chlorobenzenepropanoic acid, (R,S)-4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID, Baclofen, British Pharmacopoeia (BP) Reference Standard, Baclofen, European Pharmacopoeia (EP) Reference Standard, F2173-1127, (+/-)- beta-(Aminoethyl)-4- chlorobenzenepropanoic acid, Baclofen, United States Pharmacopeia (USP) Reference Standard, Baclofen, Pharmaceutical Secondary Standard; Certified Reference Material, ( inverted exclamation markA)-|A-(Aminomethyl)-4-chlorobenzenepropanoic acid, Baclofen solution, 500 mug/mL in methanol, ampule of 1 mL, certified reference material

ID: 1194

InChIKey: KQJSQWZMSAGSHN-JJWQIEBTSA-N
SMILES: CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 122724
synonyms found at PubChem are:
celastrol, 34157-83-0, Tripterine, Tripterin, (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Celastrol, Celastrus scandens, UNII-L8GG98663L, C29H38O4, NSC70931, NSC 70931, CHEBI:63959, 3-Hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic Acid, L8GG98663L, (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid, D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, (20alpha)-, SR-05000002679, MLS002701906, triterpene, Spectrum_000335, Spectrum2_000150, Spectrum3_000233, Spectrum4_001966, Spectrum5_000805, D0I9XH, AC1L3V4O, SCHEMBL14954, BSPBio_001905, KBioGR_002436, KBioSS_000815, SPECTRUM201664, MLS006011086, DivK1c_000718, SPBio_000260, AC1Q6P61, DTXSID2040993, KBio1_000718, KBio2_000815, KBio2_003383, KBio2_005951, KBio3_001405, KQJSQWZMSAGSHN-JJWQIEBTSA-N, MolPort-003-665-482, NINDS_000718, BDBM205457, HMS1923A13, HMS3649E12, BCP07973, EBD30960, CC0152, CCG-39919, MFCD03424073, NSC-70931, s1290, ZINC19795938, Celastrol, >=98% (HPLC), solid, AKOS025311497, AC-6031, API0001923, CS-0409, GS-6082, IDI1_000718, NCGC00178913-01, NCGC00178913-04, HY-13067, NCI60_038570, S492, SC-19832, SMR004702874, LS-157465, N1731, ST24050307, W-5302, 157C830, Q-100413, SR-05000002679-1, SR-05000002679-3, SR-05000002679-4, (20alpha)-3-hydroxy-2-oxo-D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oate, (20alpha)-3-hydroxy-2-oxo-D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, (2R,4aS,6aS,12bR,14aS,14bR)-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-2-picenecarboxylic acid, 1,2,3,4,4a,5,6,6a, 11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b, 14a-hexamethyl-11-oxo-2-Picenecarboxylic acid, 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid, 2-Picenecarboxylic acid,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, 3-Hydroxy-9.beta.,13.alpha.-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

ID: 1195

InChIKey: KQPYUDDGWXQXHS-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=O)C=CC2=O)C(=C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3806
synonyms found at PubChem are:
juglone, 5-Hydroxy-1,4-naphthoquinone, 481-39-0, 5-Hydroxy-1,4-naphthalenedione, Regianin, Juglon, Nucin, Walnut extract, 5-Hydroxynaphthalene-1,4-dione, 5-Hydroxynaphthoquinone, Akhnot, Yuglon, 8-Hydroxy-1,4-naphthoquinone, C.I. Natural Brown 7, 5-Hydroxy-p-naphthoquinone, 1,4-NAPHTHALENEDIONE, 5-HYDROXY-, 1,4-Naphthoquinone, 5-hydroxy-, C.I. 75500, Juglane, Jugnlon, Iuglon, Caswell No. 515AA, 1,4-Naphthoquinone, 8-hydroxy-, 5-Hydroxy-1,4-naphthosemiquinone, 5-Hydroxy-1,4-naftochinon, UNII-W6Q80SK9L6, NSC 153189, NSC 622948, CCRIS 5423, EINECS 207-567-5, 5-Hydroxy-1,4-naftochinon [Czech], BRN 1909764, CHEMBL43612, W6Q80SK9L6, 5-Hydroxy-1,4-naphthlenedione, 5-hydroxy-1,4-dihydronaphthalene-1,4-dione, 8-Hydroxy-1,4-naphthalenedione, CHEBI:15794, KQPYUDDGWXQXHS-UHFFFAOYSA-N, NCI 2323, NSC34266, IN1286, NSC153189, NSC622948, 1, 8-hydroxy-, J-650071, Q-100522, WLN: L66 BV EVJ GQ, 5-hydroxy-1,4-naphtoquinone, Antibiotic PD7, 5-hydroxy-1,4- naphthalenedione, Avastin+/-Tarceva, Spectrum_000415, 3b7j, ACMC-1AFTN, Spectrum2_000778, Spectrum3_001228, Spectrum4_001769, Spectrum5_000357, JUGLONE CRYSTALLIZED, D02FPF, D08PZH, D0C0NH, AC1L1GR8, AC1Q6B0X, 5-HNQ, SCHEMBL34185, BSPBio_001157, BSPBio_002676, KBioGR_000497, KBioGR_002257, KBioGR_002470, KBioSS_000497, KBioSS_000895, KBioSS_002477, SPECTRUM300038, 4-08-00-02368 (Beilstein Handbook Reference), DivK1c_001026, SPBio_000856, AC1Q794F, 5-Hydroxy-[1,4]Naphthoquinone, DTXSID0031504, BDBM24777, CTK8B1734, HMS503M13, KBio1_001026, KBio2_000497, KBio2_000895, KBio2_002470, KBio2_003065, KBio2_003463, KBio2_005038, KBio2_005633, KBio2_006031, KBio2_007606, KBio3_000913, KBio3_000914, KBio3_002176, KBio3_002948, 5-hydroxy-naphthalene-1,4-dione, 1,4-Naphthalenedione,5-hydroxy-, cMAP_000058, MolPort-000-725-926, NINDS_001026, Bio1_000441, Bio1_000930, Bio1_001419, Bio2_000409, Bio2_000889, HMS1362I19, HMS1792I19, HMS1923G07, HMS1990I19, HMS3403I19, ZINC526257, 5-hydroxy-1,4-naphthoquinone, 4, ACM481130, ANW-30636, CCG-40256, NSC-34266, 5-Hydroxy-1,4-naphthoquinone, 97%, AKOS001576598, 5-Hydroxy-1,4-naphthalenedione, 9CI, ACN-049171, FCH1114383, LS-2142, MCULE-5238429657, NSC-153189, NSC-622948, QC-1358, RTR-030750, SDCCGMLS-0066542.P001, IDI1_001026, IDI1_002164, KS-0000195Q, SMP1_000168, NCGC00095247-01, NCGC00095247-02, NCGC00095247-03, NCGC00095247-04, NCGC00095247-05, 1,4-Naphthoquinone, 5-hydroxy- (8CI), AN-23490, CC-21839, CI 75500, KB-73530, ZB014304, AB0019716, DB-005382, 1,4-dihydro-1,4-dioxo-5-hydroxynaphthalene, AM20040546, FT-0627559, ST50330598, V0179, C03840, C-05811, SR-05000002406, I14-6718, SR-05000002406-1, F0451-0746, InChI=1/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12, 481-13-0, JUG

ID: 1196

InChIKey: KQQDWFXHLGVZKX-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=C(C=C3)C(C)(C)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "K Du" "O Zegarra-Moran" "AS Verkman" "N Pedemonte" "GL Lukacs" "LJ Galietta"

CID is 5235339
synonyms found at PubChem are:
AC1NR6JX, Oprea1_271611, AKOS002939780, 4-tert-butyl-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide

ID: 1197

InChIKey: KRNOSIJCJVCXKU-WRWGMCAJSA-N
SMILES: CCCCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"A Kato" "A Mingot" "Y Blériot" "T Legigan" "V Cendret" "P Parenti" "S Thibaudeau" "F Becq" "J Bertrand" "C Norez" "I Adachi" "J Désiré" "M Forcella"

CID is 12766473
synonyms found at PubChem are:
N-Hexyl-DNJ, SCHEMBL2789051, CHEMBL1651550, BDBM18356, (2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-3,4,5-triol, (2R)-1-Hexyl-2alpha-(hydroxymethyl)piperidine-3beta,4alpha,5beta-triol

ID: 1198

InChIKey: KRWMERLEINMZFT-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4578
synonyms found at PubChem are:
o6-benzylguanine, 6-O-Benzylguanine, 19916-73-5, 6-(Benzyloxy)-7H-purin-2-amine, O(6)-Benzylguanine, 2-amino-6-benzyloxypurine, 2-Amino-6-(benzyloxy)purine, O(6)-Bgua, 6-(Benzyloxy)guanine, 6-(benzyloxy)-9H-purin-2-amine, 6-Benzyloxyguanine, 6-Benzyloxy guanine, 6-(Phenylmethoxy)-1H-purin-2-amine, 2-Amino-6-(phenylmethoxy)-9H-purine, O6-BG, UNII-01KC87F8FE, 1H-Purin-2-amine, 6-(phenylmethoxy)-, 6-BENZYLGUANINE, Purine, 2-amino-6-(benzyloxy)-, NSC 637037, 01KC87F8FE, CHEMBL407874, 6-benzyloxy-7H-purin-2-amine, 6-phenylmethoxy-7H-purin-2-amine, NSC637037, 1000874-21-4, SMR000326791, 916B735, CCRIS 9383, 6-(benzyloxy)-3h-purin-2-amine, O6 -benzylguanine, O-6-Benzylguanine, O(6) Benzylguanine, PubChem9681, Purine, 8CI), AC1Q4XUE, Lopac-B-2292, D0B5BG, AC1L1IH7, 6-benzyloxy-2-amino-purine, Lopac0_000181, SCHEMBL61740, KSC542O1R, MLS000859930, MLS001074887, MLS006010145, 6-benzyloxy-9H-purin-2-amine, BDBM5491, 2-Amino-6-benzyloxy-9H-purine, 0.4 CH3OH, CTK4E2718, 6-Benzyloxy-9H-purin-2-ylamine, DTXSID20173700, KRWMERLEINMZFT-UHFFFAOYSA-N, MolPort-001-769-965, MolPort-019-918-664, 6-(phenylmethoxy)purine-2-ylamine, HMS2234P23, HMS3260F03, HMS3369A16, BCP08777, KRX-0402, KS-00000DP7, O6-Substituted Guanine Deriv. 31, ZINC5425464, 6-(Benzyloxy)-7H-purin-2-ylamine, Tox21_500181, AN-984, ANW-43110, MFCD00269931, SBB069180, AKOS015919415, AKOS015963409, AKOS028109331, 9H-Purin-2-amine,6-(phenylmethoxy)-, AC-1076, CB-1184, CCG-204276, CS-W002585, DB11919, KS-5281, LP00181, LS20601, NSC-637037, RL02491, RTR-030959, 9H-Purin-2-amine, 6-(phenylmethoxy)-, NCGC00015144-01, NCGC00015144-02, NCGC00015144-03, NCGC00015144-04, NCGC00093660-01, NCGC00093660-02, NCGC00260866-01, AJ-54058, BC215630, BR-47518, H350, NCI60_012280, Purine, 2-amino-6-(benzyloxy)- (, ), SC-02184, SY008080, O6-Benzylguanine, >=98% (TLC), solid, AB0013002, AB1003839, LS-126405, TR-030959, 4CH-006286, AM20060538, EU-0100181, FT-0650712, ST24033084, Y2972, A-1974, B 2292, J10132, SR-01000075709, S07-0157, SR-01000075709-1, W-201741, OBG

ID: 1199

InChIKey: KSCFJBIXMNOVSH-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3182
synonyms found at PubChem are:
dyphylline, Diprophylline, 479-18-5, Diphylline, 7-(2,3-Dihydroxypropyl)theophylline, Lufyllin, Neothylline, Diprophyllin, Glyphylline, Aristophyllin, Diprofilline, Dipropylline, Neutrafillina, Neutraphyllin, Neutraphylline, Neutroxantina, Propyphyllin, Protheophylline, Synthophylline, Corphyllin, Diprofillin, Glyphyllin, Neophyllin, Hidroxiteofillina, Neostenovasan, Silbephylline, Asthmolysin, Astrophyllin, Coronarin, Glyfyllin, Hiphyllin, Hyphylline, Liactemin, Neophylline, Neotilina, Neutrafil, Purifilin, Silbephyllin, Solufilin, Solufyllin, Soluphyllin, Thefylan, Circain, Coronal, Droxine, Dyflex, Neophyl, Neufil, Tefilan, Teofen, Dilor, Theal, Neo-Vasophylline, COR-theophylline, AFI-Phyllin, Dihydroxypropyl theophylline, Dihydroxypropyl theopylin, Diprophyllinum, Glyphyllinum, Astmamasit, Diprofilina, Isophyllen, Circair, Tesfen, Theal ampules, Neophyllin M, Diphyllin (VAN), Diprofillina, Iphyllin, Diprofillina [DCIT], Dilor-400, Dilor G, (1,2-Dihydroxy-3-propyl)thiophyllin, 7-(2,3-Dioxypropyl)theophylline, 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine, Diprofilina [INN-Spanish], Dyphylline [USAN], Diprophyllinum [INN-Latin], 7-(beta,gamma-Dihydroxypropyl)theophylline, Dihydroxypropyltheophylline, Dihydroxypropyl theopylin (german), (+-)-dyphylline, Dyphylline (USP), Dyphylline [USP], Lufyllin (TN), 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine, 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-, (+-)-diprophylline, HSDB 3322, 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, (+-)-7-(2,3-Dihydroxypropyl)theophylline, C10H14N4O4, EINECS 207-526-1, NSC 14305, Diprophylline (JAN/INN), 7-[2,3-Dihydroxypropyl]-theophylline, BRN 0284563, 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, Theophylline, 7-(2,3-dihydroxypropyl)-, 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione, MLS000069403, CHEBI:4728, KSCFJBIXMNOVSH-UHFFFAOYSA-N, 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl, 7-DIHYDROXYPROPYLTHEOPHYLLINE, 7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, SMR000059068, DSSTox_CID_2975, 7-(2,3-dimethylxanthine, DSSTox_RID_76813, DSSTox_GSID_22975, 1,3-dihydroxypropyl)xanthine, Diprophylline (7-(2,3-Dihydroxypropyl)theophylline), Q-201013, Theophylline,3-dihydroxypropyl)-, 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, 7-(2,3-dihydroxypropyl)-theophylline, 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-, (+-)-, 7-(.beta.,.gamma.-Dihydroxypropyl)theophylline, WLN: T56 BN DN FNVNVJ B1YQ1Q F1 H1, SR-01000002972, 1H-Purine-2, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-, 7-(2,3-dihydroxypropyl)-1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, Dyphylline(Dilor), NCGC00016455-01, Diprophylline,(S), CAS-479-18-5, Prestwick_465, Dyphylline (Dilor), (+/-)-dyphylline, Diprophylline [INN], PubChem9686, (+/-)-diprophylline, Spectrum_000809, AC1L1FCW, AC1Q6LEB, Opera_ID_1754, Prestwick0_000033, Prestwick1_000033, Prestwick2_000033, Prestwick3_000033, Spectrum2_000090, Spectrum3_000411, Spectrum4_000530, Spectrum5_000953, D02PWM, AC1Q3Z7Q, SCHEMBL8192, CHEMBL1752, Oprea1_363458, BSPBio_000125, BSPBio_001962, KBioGR_001139, KBioSS_001289, 5-26-14-00070 (Beilstein Handbook Reference), KSC491G3P, MLS001076466, DivK1c_000022, SPECTRUM1500269, SPBio_000020, SPBio_002046, BPBio1_000139, GTPL7070, DTXSID6022975, BDBM82016, CTK3J1337, HMS500B04, KBio1_000022, KBio2_001289, KBio2_003857, KBio2_006425, KBio3_001182, KSCFJBIXMNOVSH-UHFFFAOYSA-, MolPort-001-783-701, NINDS_000022, HMS1568G07, HMS1920K08, HMS2091B13, HMS2095G07, HMS2232K09, HMS3372H13, HMS3654D18, HMS3712G07, Pharmakon1600-01500269, BCP02003, HY-B0128, KS-00000XR5, NSC_3182, NSC14305, NSC40844, Tox21_110444, BBL009638, CCG-38906, MFCD00005759, NSC-14305, NSC-40844, NSC756753, s1504, SBB003125, STK796769, AKOS005203076, Tox21_110444_1, API0002415, BCP9000631, CS-1901, DB00651, MCULE-5509227834, NSC-756753, IDI1_000022, SMP1_000108, NCGC00018099-02, NCGC00018099-03, NCGC00018099-04, NCGC00018099-05, NCGC00018099-06, NCGC00018099-09, NCGC00018099-10, NCGC00089736-02, NCGC00089736-03, NCGC00178894-01, NCGC00178894-02, AC-11186, AK164455, AN-45166, AS-12460, CAS_479-18-5, CC-23014, SBI-0051359.P003, AB1009414, DB-051485, LS-149505, AB00051977, D3600, FT-0632186, ST50298840, 7-(beta.,.gamma.-Dihydroxypropyl)theophylline, C07819, D00691, Neothylline, Lufyllin, diprophylline,Dyphylline, AB00051977-15, AB00051977_16, AB00051977_17, 1,4-Benzenedimethanamine, N1,N4-di-2-pyridinyl-, C-30388, I14-5830, SR-01000002972-2, SR-01000002972-3, SR-01000002972-4, BRD-A00827783-001-05-5, BRD-A00827783-001-15-4, Diprophylline, European Pharmacopoeia (EP) Reference Standard, Dyphylline, United States Pharmacopeia (USP) Reference Standard, 52756-53-3, InChI=1/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3

ID: 1200

InChIKey: KSEBMYQBYZTDHS-HWKANZROSA-N
SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 445858
synonyms found at PubChem are:
ferulic acid, trans-Ferulic Acid, 1135-24-6, 4-Hydroxy-3-methoxycinnamic acid, 537-98-4, trans-4-Hydroxy-3-methoxycinnamic acid, 3-(4-Hydroxy-3-methoxyphenyl)acrylic acid, (E)-Ferulic acid, ferulate, Coniferic acid, Ferulic acid, trans-, Cinnamic acid, 4-hydroxy-3-methoxy-, 3-methoxy-4-hydroxycinnamic acid, (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid, 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid, UNII-AVM951ZWST, Cinnamic acid, 4-hydroxy-3-methoxy-, (E)-, (E)-4-Hydroxy-3-methoxycinnamic acid, 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (E)-4'-Hydroxy-3'-methoxycinnamic acid, 4-Hydroxy-3-methoxy cinnamic acid, Cinnamic acid, 4-hydroxy-3-methoxy-, trans-, EINECS 208-679-7, AVM951ZWST, (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid, Ferulic acid dehydrogenation homopolymer, Fumalic acid (Ferulic acid), 4-Hydroxy-3-methoxycinnamate, CHEMBL32749, 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (E)-, 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid homopolymer, CHEBI:17620, NSC2821, KSEBMYQBYZTDHS-HWKANZROSA-N, (2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylic acid, 3-Methoxy-4-hydroxy-trans-cinnamate, trans-Ferulate, (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid, 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-, C10H10O4, 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid, 97274-61-8, FER, (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid, CCRIS 3256, CINNAMIC ACID,4-HYDROXY,3-METHOXY FERULIC ACID, NSC 2821, EINECS 214-490-0, NSC 51986, NSC 674320, 3-methoxy-4-hydroxy-trans-cinnamic acid, SMR000112202, ferulic acid, (E)-isomer, (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid, ferulasaure, KSEBMYQBYZTDHS-UHFFFAOYSA-N, Fumalic acid, (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoate, CCRIS 7127, CCRIS 7575, HSDB 7663, (E)-Ferulate, Ferulic acid, E-, Ferulic acid (M5), PubChem8183, 3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid, Ferulic Acid ,(S), Ferulic Acid, Synthetic, AC1L9IOI, Spectrum5_000554, bmse000459, bmse000587, bmse010211, D03SLR, trans-Ferulic acid, 99%, AC1Q5T8U, SCHEMBL15673, BSPBio_003168, MLS001066385, MLS001332483, MLS001332484, MLS002207079, MLS006011435, SPECTRUM1501017, trans-Ferulic acid, >=99%, AC1Q469S, ZINC58258, MolPort-000-490-395, MolPort-011-018-530, HMS1921D05, HMS2269P04, (E)-4-Hydroxy-3-methoxycinnamate, trans-4-Hydroxy-3-methoxycinnamate, ALBB-013505, BCP21231, BCP21789, HY-N0060, NSC-2821, NSC51986, STR00961, (E)-4-hydroxy-3-methoxy-Cinnamate, (E)4-hydroxy-3-methoxycinnamic acid, BBL010345, BDBM50214744, CCG-38860, CF0041, MFCD00004400, NSC-51986, s2300, SBB000326, STK801551, trans-4-Hydroxy-3-methoxycinnamicacid, AKOS000263735, AC-7965, ACN-035275, AN-8448, BCP9000163, DB07767, OR11310, PS-3435, RP17475, RP25300, RTR-002615, RTR-037023, SDCCGMLS-0066667.P001, trans-3-methoxy-4-hydroxycinnamic acid, (E)-4-hydroxy-3-methoxy-Cinnamic acid, 3-(4-Hydroxy-3-methoxyphenyl)propenoate, 4-Hydroxy-3-Methoxycinnamic Acid, 99%, 4-Hydroxy-3-methoxycinnamic acid, trans, NCGC00094889-01, NCGC00094889-02, NCGC00094889-03, NCGC00094889-04, 24276-84-4 (mono-hydrochloride salt), AC-10321, AJ-09852, AN-45706, BR-32258, BR-49078, KB-51871, KB-81701, LS-54115, SC-17540, SMR004703246, ST097625, AB1002979, AB2000725, AX8011844, AX8021297, KB-192658, ST2410362, TL8000398, TR-002615, TR-037023, AM20060784, CS-0007108, N1878, C01494, J10038, J10187, W-2799, A829775, SR-01000765539, (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoate, I01-2280, J-002980, SR-01000765539-3, ferulic acid (trans-4-hydroxy-3-methoxycinnamic acid), trans-4-Hydroxy-3-methoxycinnamic acid; Ferulic acid, (E)-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enoic acid, 3-(4-Hydroxy-3-methoxyphenyl)acrylic acid, 99% 10g, 3-(4-HYDROXY-3-METHOXYPHENYL)PROP-2-ENOICACID, 055E203F-B305-4B7F-8CE7-F9C0C03AB609, 3986A1BE-A670-4B06-833B-E17253079FD8, Ferulic acid, European Pharmacopoeia (EP) Reference Standard, trans-Ferulic acid, certified reference material, TraceCERT(R), 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (E)- (9CI), Ferulic acid, United States Pharmacopeia (USP) Reference Standard, trans-Ferulic acid, matrix substance for MALDI-MS, >=99.0% (HPLC), 4-Hydroxy-3-methoxycinnamic acid, mixture of isomers, analytical reference material, Ferulic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, 1356408-74-6, 831-85-6, InChI=1/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13

ID: 1201

InChIKey: KSMGXOJIWMFMLJ-QBATWECUSA-N
SMILES: CC(=O)O[C@@H]1[C@H]([C@@]2(C(CC[C@@]3(C24C(O4)C(=O)O[C@H]3C5=COC=C5)C)[C@@]6(C1C(C(=O)C=C6)(C)C)C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 98042578
synonyms found at PubChem are:
6beta-ACETOXYGEDUNIN

ID: 1202

InChIKey: KSMZUKWIDPCGBS-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC3(C(CCC2(O3)C)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5176389
synonyms found at PubChem are:
3,7-EPOXYCARYOPHYLLAN-6-OL, KBio2_003756, Spectrum_000708, SpecPlus_000232, Spectrum2_001774, Spectrum3_001300, Spectrum4_001460, Spectrum5_000079, BSPBio_002939, KBioGR_001979, KBioSS_001188, SPECTRUM300118, DivK1c_006328, SPBio_001667, CHEMBL1488067, KBio1_001272, KBio2_001188, KBio2_006324, KBio3_002159, CCG-38423, SDCCGMLS-0066482.P001, NCGC00095588-01, NCGC00095588-02, SR-05000002482, SR-05000002482-1

ID: 1203

InChIKey: KSPIYJQBLVDRRI-UHFFFAOYSA-N
SMILES: CCC(C)C(C(=O)O)NC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 560437
synonyms found at PubChem are:
N-Methylisoleucine, MeIle, 3-methyl-2-methylaminopentanoic acid, 3-methyl-2-(methylamino)pentanoic acid, N-Methylisoleucine #, AC1LBMCH, Spectrum_001286, AC1Q5SKQ, Spectrum2_001839, Spectrum3_001108, Spectrum4_001948, Spectrum5_000657, SCHEMBL43380, BSPBio_002816, KBioGR_002358, KBioSS_001766, SPECTRUM1400136, SPBio_001917, CHEBI:64350, KBio2_001766, KBio2_004334, KBio2_006902, KBio3_002036, KSPIYJQBLVDRRI-UHFFFAOYSA-N, CCG-38460, AKOS010573305, SDCCGMLS-0066878.P001, 2-(Methylamino)-3-methylpentanoic acid, NCGC00095743-01, NCGC00095743-02, (2S)-3-methyl-2-(methylamino)pentanoic acid, SR-05000002378, SR-05000002378-1

ID: 1204

InChIKey: KSRLIXGNPXAZHD-HAZZGOGXSA-M
SMILES: C1C(=O)N=C(N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6604100
synonyms found at PubChem are:
DANTROLENE SODIUM, Dantrolene sodium salt, Dantrium, Dantrolene (sodium), UNII-28F0G1E0VF, Dantamacrin, Dantrix, Dantrolene Sodium (anhydrous), 14663-23-1, Dantrolene sodium [USAN:BAN:JAN], EINECS 238-706-8, Dantrolene sodium anhydrous, Sodium dantrolene, Dantrolene, Sodium Salt, 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin sodium, 28F0G1E0VF, Dantrolene sodium hemiheptahydrate, Ryanodex, 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-, sodium salt, F 440, F-440, Hydantoin, 1-((5-(p-nitrophenyl)furfurylidene)amino)-, sodium salt, 1-((5-(4-Nitrophenyl)furfurylidene)amino)imidazolidine-2,4-dione, sodium salt, 24868-20-0, SMR000326766, 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin sodium salt hydrate, CHEBI:4318, Hydantoin, 1-((5-(p-nitrophenyl)furfurylidene)amino)-, sodium salt, hydrate (2:7), 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione Sodium Salt Hemiheptahydrate, 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-, sodium salt, hydrate (2:7), anhydrous dantrolene sodium, CHEMBL928, AC1O7G8U, C14H9N4O5.Na, MLS000859905, MLS002153441, 2C14H9N4O5.2Na, HMS502M20, MolPort-003-666-797, MolPort-006-069-178, HMS1568L04, HMS2092N12, HMS2095L04, HMS3261E10, HMS3266G14, HMS3712L04, 2C14H9N4O5.2Na.7H2O, CCG-40324, MFCD00079130, AKOS015895197, AKOS015895198, CCG-220291, CS-5234, NCGC00093847-01, CPD000326766, HY-14657, LS-76265, SAM002703135, AB0011237, LS-174074, B6329, D3996, EU-0100424, C07933, I06-0335, I06-0336, 1-[(5-[p-Nitrophenyl]-furfurylidene)amino]hydantoin, 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt, 1-[(5--(p-Nitro-phenyl)-fur-furyl-idene)-amino]-hydan-toin sodium salt, 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolinedione sodium salt, potassium 1-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)-4-oxo-5H-imidazol-2-olate, sodium 1-[(E)-{[5-(4-nitrophenyl)furan-2-yl]methylidene}amino]-4-oxo-5H-imidazol-2-olate, sodium 3-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)-2,5-dioxoimidazolidin-1-ide, sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-5-oxo-4H-imidazol-2-olate, 1-[[[5-(4-Io>>u+/-(1/2))-2-ss>>a<<>>u]NC(1/4)x>>u degrees +/->>u]-2,4-ssassosso paragraph signthornI feminine AAENI, 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate, Tox21_500424, CCG-221728, NCGC00261109-01, AC-25752, D 9175, 1-{(5-{p-nitrophenyl}furfurylidene)-amino}hydantoin sodium, Q-200926

ID: 1205

InChIKey: KSTGYMXUFHCTSM-UHFFFAOYSA-N
SMILES: CC(C)C1C2CCC(C2)C1N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957452
synonyms found at PubChem are:
AGN 192403 hydrochloride, 175521-95-6, 1021868-90-5, SR-01000075245, EU-0100109, SCHEMBL1765147, (1R,2R,3R,4S)-3-Isopropylbicyclo[2.2.1]heptan-2-amine hydrochloride, CTK8E7203, MolPort-023-275-988, AKOS024456370, RT-011220, A-252, J-011118, SR-01000075245-1, SR-01000075245-3, (2-endo,3exo)-3-(Methylethyl)-bicyclo[2.2.1]heptan-2-amine hydrochloride

ID: 1206

InChIKey: KTCXMTWSISEJFZ-UHFFFAOYSA-N
SMILES: C1CC2=NC3=CC=CC=C3CN2C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3046290
synonyms found at PubChem are:
Desoxypeganine hydrochloride, 61939-05-7, Pegene hydrochloride, Deoxyvasicine hydrochloride, Deoxypeganine hydrochloride, Vasicine, deoxy-, hydrochloride, 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline hydrochloride, Pyrrolo(2,1-b)quinazoline, 1,2,3,9-tetrahydro-, monohydrochloride, 1H,2H,3H,9H-pyrrolo[2,1-b]quinazoline hydrochloride, Deoxyvasicine HCl, Deoxypeganine hydrochloride dihydrate, SR-01000783332, Desoxypeganine HCl, AC1MIJUN, MLS001202231, SPECTRUM1505169, SPECTRUM1505243, 495-59-0 (Parent), CHEMBL1376378, CTK8F9087, DTXSID50210970, MolPort-003-665-618, CCG-38777, AKOS024461964, NCGC00095710-01, NCGC00095710-02, AN-39125, SMR000564986, LS-139680, FT-0713103, MLS-0066767.0001, 939D057, SR-01000783332-3, Z2295423882, MolPort-000-736-533, MCULE-9508899155

ID: 1207

InChIKey: KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES: C/C/1=C\CC[C@@]2([C@H](O2)[C@@H]3[C@@H](CC1)C(=C)C(=O)O3)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"KA Teske" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile"

CID is 7251185
synonyms found at PubChem are:
parthenolide, 20554-84-1, (-)-Parthenolide, CHEBI:7939, Parthenolide, Tanacetum parthenium, 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone, partenolide, C15H20O3, Prestwick2_000550, Prestwick3_000550, D0M4KE, Epitope ID:115014, SCHEMBL8220, BSPBio_000599, BSPBio_001308, MLS002153872, BPBio1_000659, CHEMBL465158, SCHEMBL13367522, BCBcMAP01_000041, Parthenolide, >=98% (HPLC), MolPort-003-959-089, MolPort-008-268-168, HMS1361B10, HMS1569N21, HMS1791B10, HMS1989B10, HMS2096N21, HMS3402B10, HMS3713N21, 29552-41-8, BCP10404, HY-N0141, ZINC4492886, MFCD00134592, AKOS016010226, CCG-208244, CS-1919, IDI1_033778, NCGC00163415-01, AJ-51217, AS-17479, Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-, SMR001233226, AB0019832, AB00513860, ST24048874, V0355, X-1866, 552P418, Q-100253, Parthenolide, United States Pharmacopeia (USP) Reference Standard, (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, (3aS,10R,11R,11aS,6E)-3-Methylene-6,10-dimethyl-10,11-epoxy-1-oxa-2,3,3a,4,5,8,9,10,11,11a-decahydro-1H-cyclopentacyclodecene-2-one

ID: 1208

InChIKey: KTGRHKOEFSJQNS-BDQAORGHSA-N
SMILES: CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.C(=O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 146571
synonyms found at PubChem are:
Escitalopram oxalate, 219861-08-2, Lexapro, Cipralex, (S)-Citalopram Oxalate, Escitalopram (oxalate), Citalopram Oxalate, UNII-5U85DBW7LO, (S)-(+)Citalopram oxalate, 5U85DBW7LO, (S)-(+)-Citalopram Oxalate, (S)-1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate, NCGC00095903-01, Lu 26-054-0, Lexapro (TN), DSSTox_CID_26003, DSSTox_RID_81282, DSSTox_GSID_46003, C22H23FN2O5, S-(+)-1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile oxalate, 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-, ethanedioate (1:1), S-(+)-5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, oxalate, CAS-219861-08-2, Lu-26-054-0, Gaudium, Entact, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;oxalic acid, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile; oxalic acid, (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Oxalate, AC1L3TGZ, Escitalopram oxalate [USAN], SCHEMBL35123, cc-372, MLS001401408, SPECTRUM1505216, (+)-(S)-Citalopram oxalate, MLD-55, CHEMBL1200322, DTXSID1046003, AOB4715, Escitalopram oxalate (JAN/USAN), Escitalopram oxalate [USAN:USP], KTGRHKOEFSJQNS-BDQAORGHSA-N, MolPort-003-666-613, HMS2051D11, HMS2231M16, HMS3370I17, HMS3393D11, HMS3713D16, Pharmakon1600-01505216, BCP05686, Tox21_111535, BG0433, CCG-39559, HY-14258A, NSC758934, AKOS016340275, Tox21_111535_1, AC-6770, AN-9671, CS-2054, KS-1263, NC00194, NSC-758934, NCGC00178555-02, AN-13009, CPD000469191, SAM001246668, SMR000469191, AB0012102, AX8019428, LS-183519, LU-260540, TL8001823, E0958, FT-0650410, ST24046691, D02567, Escitalopram oxalate, >=98% (HPLC), powder, J90016, Escitalopram pound Escitalopram Oxalate pound(c), 861E082, SR-01000763053, SR-01000763053-3, UNII-B5RDX2419X component KTGRHKOEFSJQNS-BDQAORGHSA-N, Escitalopram oxalate, EuropePharmacopoeia (EP) Reference Standard, Escitalopram oxalate, United States Pharmacopeia (USP) Reference Standard, Escitalopram for system suitability, EuropePharmacopoeia (EP) Reference Standard, Escitalopram Oxalate, Pharmaceutical Secondary Standard; Certified Reference Material, (+)-(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate, (1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Ethanedioate, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile; oxalic acid, S-(+)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate

ID: 1209

InChIKey: KTJWHJNBTXITCB-UHFFFAOYSA-N
SMILES: C1CCC(C1)N2C=NC3=C2N=CN=C3N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 12852
synonyms found at PubChem are:
9-Cyclopentyladenine, 9-Cyclopentyl-9H-adenine, 6-Amino-9-cyclopentylpurine, 715-91-3, Adenine, 9-cyclopentyl-, 9-cyclopentylpurin-6-amine, 9H-Purin-6-amine, 9-cyclopentyl-, 9-Cyclopentyl-9H-purin-1-amine, Adenine, 9-cyclopentyl- (8CI), 9H-ADENINE, 9-CYCLOPENTYL-, NSC 19486, BRN 0211535, CHEMBL294590, 9-Cyclopentyl-9H-purin-6-ylamine, NSC19486, 9-(cyclopentyl)-adenine, D0B3UE, AC1L20HZ, Lopac0_000273, SCHEMBL978424, CTK2H9481, DTXSID70221720, 6-Amino-9-cyclopentyl-9H-purine, ZINC1566904, 9H-Purin-1-amine, 9-cyclopentyl-, BDBM50009680, NSC-19486, CCG-204368, NCGC00162114-01, NCGC00162114-02, LS-15066, 9H-Purin-1-amine, 9-cyclopentyl- (9CI), 9H-Purin-6-amine, 9-cyclopentyl- (9CI)

ID: 1210

InChIKey: KTMLZVUAXJERAT-UHFFFAOYSA-N
SMILES: CN1C(=CC(=O)N(C1=O)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 167980
synonyms found at PubChem are:
Urapidil hydrochloride, 64887-14-5, Urapidil HCl, Urapidil (hydrochloride), UNII-PVU92PZO12, PVU92PZO12, NCGC00094502-01, Ebrantil (TN), DSSTox_CID_25812, DSSTox_RID_81149, DSSTox_GSID_45812, 2,4(1H,3H)-Pyrimidinedione,6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-,hydrochloride (1:1), SMR000058525, SR-01000075295, CAS-64887-14-5, AC1Q3EJC, AC1L50YN, Urapidil Hydrochloride,(S), Urapidil hydrochloride, solid, C20H30ClN5O3, MLS000758309, MLS001424033, SCHEMBL1321654, CHEMBL1256716, DTXSID2045812, CTK5C1831, HY-B0354A, MolPort-003-959-837, HMS1570F12, Pharmakon1600-01503100, BCP23389, Tox21_111286, Tox21_501265, BG0350, NSC758226, s2025, AKOS015994621, Tox21_111286_1, AC-8089, AN-8379, API0000876, CCG-100798, CS-2400, H61U751, HS-0064, LP01265, NC00048, NSC-758226, ACM34661751, NCGC00016066-14, NCGC00261950-01, 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethylpyrimidine-2,4(1h,3h)-dione hydrochloride(1:1), CPD000058525, SAM001247001, SC-96704, AB2000431, EU-0101265, FT-0675734, U-100, V0313, D08662, SR-01000075295-1, SR-01000075295-3, SR-01000075295-9, SR-01000075295-10, 6[[3-[4-(o-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil hydrochloride, 2,4(1H,3H)-Pyrimidinedione, 6-((3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride, 6-((3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride, 6-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propylamino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride, 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride, 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethyl-pyrimidine-2,4-dione hydrochloride, 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione hydrochloride, 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione;hydrochloride, AKOS026749783

ID: 1211

InChIKey: KTNROWWHOBZQGK-UHFFFAOYSA-N
SMILES: CCNCC(C1=CC(=CC=C1)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 13668
synonyms found at PubChem are:
Effortilvet, Apocretin, Effontil, Funasol, Phetanol, Phetasin, Pulsamin, Updormin, Tonus-Forte, Eti-Puren, dl-Effortil hydrochloride, Ethylephrine hydrochloride, dl-Etilefrin hydrochloride, dl-Ethylphenylephrine hydrochloride, EINECS 213-398-8, dl-N-Ethylnorphenylephrine hydrochloride, 1-(3-Hydroxyphenyl)-2-ethylaminoethanol hydrochloride, dl-1-(3-Hydroxyphenyl-2-ethylaminoethanol hydrochloride, alpha-((Ethylamino)methyl)-m-hydroxybenzyl alcohol hydrochloride, dl-1-(3-Hydroxyphenyl)-1-hydroxy-2-ethylaminoethane hydrochloride, Benzenemethanol, alpha-((ethylamino)methyl)-3-hydroxy-, hydrochloride, BENZYL ALCOHOL, alpha-((ETHYLAMINO)METHYL)-m-HYDROXY-, HYDROCHLORIDE, C10H15NO2.HCl, AC1L2286, SBB057403, ( -)-Ethylphenylephrine hydrochloride, AKOS025116943, AN-5824, LS-42975, ( -)-N-Ethylnorphenylephrine hydrochloride, 2-(ethylamino)-1-(3-hydroxyphenyl)ethan-1-ol, chloride, ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]azanium chloride, ethyl-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]ammonium chloride, etilefrine hydrochloride, 943-17-9, Etilefrine HCl, Circupon, Kertasin, 534-87-2, 3-[2-(ethylamino)-1-hydroxyethyl]phenol hydrochloride, Etilefrin Hydrochloride, 2-Ethylamino-1-(3-hydroxyphenyl)ethanol Hydrochloride, Etilefrine hydrochloride (TN), Thomasin, 3-(2-(Ethylamino)-1-hydroxyethyl)phenol hydrochloride, 10128-36-6, 3-[2-(ethylamino)-1-hydroxyethyl]phenol;hydrochloride, Cardanat, Efortil, Etilefrin dl-form hydrochloride, Etilefrine hydrochloride [JAN], (+-)-Ethylphenylephrine hydrochloride, Etilefrin dl-form HCl, (+-)-N-Ethylnorphenylephrine hydrochloride, NCGC00016496-01, CAS-534-87-2, AC1L4V6V, DSSTox_CID_25322, DSSTox_RID_80801, DSSTox_GSID_45322, labotest-bb lt00244796, ARONIS24372, SCHEMBL207591, ETILEFRIN, HYDROCHLORIDE, AC1Q39V9, CHEMBL3187408, DTXSID1045322, CHEBI:31582, CTK6F2345, Etilefrine hydrochloride (JP17), MolPort-003-910-952, HMS1571K15, Tox21_110457, AKOS005267166, (+/-)-Ethylphenylephrine Hydrochloride, CCG-221017, MCULE-7723795613, NE60393, VA10863, AS-13925, O390, SC-17935, TR-029495, E0381, FT-0603527, FT-0668420, ST50443863, EN300-03375, D01573, 943E179, A844915, SR-01000837506, Q-201098, SR-01000837506-2, 3-[2-(ethylamino)-1-hydroxyethyl]phenol,hydrochloride, I14-31841, 3-[2-(ethylamino)-1-oxidanyl-ethyl]phenol hydrochloride, 3-[2-(ethylamino)-1-hydroxyethyl]phenol hydrochloride(1:1), alpha-((ethylamino)methyl)-3-hydroxy-benzenemethanohydrochloride, alpha-((ethylamino)methyl)-m-hydroxy-benzylalcohohydrochloride, alpha-((ethylamino)methyl)-m-hydroxybenzylalcoholhydrochloride

ID: 1212

InChIKey: KTUFKADDDORSSI-UHFFFAOYSA-N
SMILES: CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 36816
synonyms found at PubChem are:
Diasectral, Wesfalin, CCRIS 1102, HSDB 6524, EINECS 251-980-3, IL 17803A, M&B 17,803A, AC1L1WFL, (1)-N-(3-Acetyl-4-(2-hydroxy-3-((isopropyl)amino)propoxy)phenyl)butyramide monohydrochloride, Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, monohydrochloride, (+-)-, Butyranilide, 3'-acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)-, monohydrochloride, (+-)-, C18H28N2O4.HCl, Acebutolol hydrochloride [JAN], LS-47749, [3-[2-acetyl-4-(butanoylamino)phenoxy]-2-hydroxypropyl]-propan-2-ylazanium chloride, Acebutolol hydrochloride, 34381-68-5, Acebutolol HCL, N-(3-Acetyl-4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)butyramide hydrochloride, Acebutolol (hydrochloride), MLS000069553, CHEBI:2380, 3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide hydrochloride, dl-1-(2-Acetyl-4-butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, SMR000058800, Sectral (TN), IL-17803A, (+-)-3'-acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide monohydrochloride, DSSTox_CID_25461, DSSTox_RID_80892, N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide hydrochloride, DSSTox_GSID_45461, C18H29ClN2O4, N-[3-Acetyl-4-(2 hydroxy-3-[isopropylamino]propoxy)phenyl]-butanamide, Acebutolol.HCL, N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide hydrochloride, N-[3-ACETYL-4-[2-HYDROXY-3-[(ISOPROPYL)AMINO]PROPOXY]PHENYL]BUTYRAMIDE HYDROCHLORIDE, SR-01000000133, N-(3-ACETYL-4-[2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY]PHENYL)BUTANAMIDE HYDROCHLORIDE, N-[3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]butanamide hydrochloride, N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide;hydrochloride, N-(3-ACETYL-4-[2-HYDROXY-3-(PROPAN-2-YLAMINO)PROPOXY]PHENYL)BUTANAMIDE HYDROCHLORIDE, Prestwick_512, Acebutolol hydrochloride [USP:JAN], ACEBUTOLO HCL, AC1L9AXY, Opera_ID_1259, PRENT HYDROCHLORIDE, NCGC00016827-01, ACECOR HYDROCHLORIDE, NEPTAL HYDROCHLORIDE, AC1Q39OF, SECTRAL HYDROCHLORIDE, CAS-34381-68-5, ACETANOL HYDROCHLORIDE, SCHEMBL41004, MLS001076107, MLS002222219, MLS002548874, SPECTRUM1500665, CHEMBL1200813, DTXSID5045461, CTK8F7495, KS-00000FKS, MolPort-003-666-313, HMS1568M19, HMS1921A06, IL-17803A HYDROCHLORIDE, Pharmakon1600-01500665, 37517-30-9 (Parent), BCP28416, Tox21_110633, AC-002, BG0005, CCG-39278, HY-17497A, NSC757412, s4010, Acebutolol hydrochloride (JP17/USP), AKOS015895193, Tox21_110633_1, AB03018, API0001353, CS-2637, KS-5245, M&B 17803A, M&B-17803A, MCULE-8284913115, NC00669, NSC-757412, NCGC00018215-06, NCGC00094830-01, NCGC00094830-02, NCGC00094830-03, NCGC00094830-04, AK116443, AN-16199, BC220429, CC-23635, CPD000058800, R896, SAM002264591, AX8112021, TL8002563, 4CH-016371, Acebutolol hydrochloride, analytical standard, FT-0630582, ST51014891, C07677, D00597, J10323, 381A685, A822205, C-21196, I06-0329, J-019577, SR-01000000133-3, Acebutolol Hydrochloride 1.0 mg/ml in Methanol (as free base), Acebutolol hydrochloride, European Pharmacopoeia (EP) Reference Standard, Acebutolol hydrochloride, United States Pharmacopeia (USP) Reference Standard, DL-1-(2-ACETYL-4-BUTYRAMIDO)-3-(ISOPROPYLAMINO)PROPAN-2-OL HYDROCHLORIDE, N-(3-acetyl-4-{2-hydroxy-3-[(methylethyl)amino]propoxy}phenyl)butanamide, chlo ride, N-[3-ethanoyl-4-[2-oxidanyl-3-(propan-2-ylamino)propoxy]phenyl]butanamide hydrochloride, N-(3-OOo pound>>u-4-[2-oC>>u-3-(Oi+/-u degrees .>>u)+/-uNo>>u]+/-(1/2)>>u) paragraph sign inverted exclamation marko pound degrees ., N-[3-ACETYL-4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]BUTANAMIDE HYDROCHLORIDE, AC1LCW5P, AKOS026750000, N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide; hydron; chloride

ID: 1213

InChIKey: KUAHVIUZGLGASU-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)NO1)CC(C(=O)O)N.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957558
synonyms found at PubChem are:
(RS)-AMPA hydrobromide, 171259-81-7, AMPA hydrobromide, 118896-96-1, (+/-)-AMPA hydrobromide, 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid hydrobromide, (+/-)-alpha-Amino-3-hydroxy-5-methylisoxazole- 4-propionic Acid Hydrobromide, (R,S)-|A-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide, GNF-Pf-2579, SR-01000075447, AMeP hydrobromide, (+/-)-alpha-AMINO-3-HYDROXY-5-METHYL-ISOXAZOLE-4-PROPIONIC ACID, (y)-AMPA hydrobromide, (?)-AMPA hydrobromide, EU-0100581, CHEMBL608555, SCHEMBL7200262, CTK7I4374, CTK8F0604, DTXSID60474687, OR1155T, MolPort-001-759-110, ZX-AT020823, Tox21_500581, BN0075, AKOS015910238, CCG-221885, LP00581, TRA0018692, KS-0000001Z, NCGC00093962-01, NCGC00261266-01, KB-93548, RT-011090, RT-011114, ( inverted question mark)-AMPA hydrobromide, FT-0605181, FT-0661850, G-017, (+/-)-AMPA hydrobromide, >=98% (HPLC), J-010703, SR-01000075447-1, SR-01000075447-4, I14-40260, (RS)-?-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide, 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid;hydrobromide, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide, (+/-)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid hydrobromide, ( inverted question mark)-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide

ID: 1214

InChIKey: KUAZQDVKQLNFPE-UHFFFAOYSA-N
SMILES: CN(C)C(=S)SSC(=S)N(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5455
synonyms found at PubChem are:
thiram, Tetramethylthiuram disulfide, 137-26-8, Thiuram, TMTD, Pomarsol, Thirame, Arasan, Fernasan, Nobecutan, Rezifilm, Thioscabin, Thirasan, Aapirol, Tersan, Tetrathiuram disulfide, Tetramethylthiuram, Falitiram, Formalsol, Hexathir, Kregasan, Mercuram, Normersan, Sadoplon, Spotrete, Tetrasipton, Thillate, Thiramad, Aatiram, Atiram, Fermide, Fernide, Hermal, Pomasol, Puralin, Thiotox, Thiulin, Thiulix, Heryl, Pomarsol forte, Methyl tuads, Polyram ultra, Accelerator T, Methyl Thiram, Fernasan A, Nocceler TT, Arasan-M, Bis(dimethylthiocarbamoyl) disulfide, Thiram B, Arasan-SF, Cyuram DS, Ekagom TB, Hermat TMT, Tetramethylenethiuram disulfide, Accel TMT, Accelerator thiuram, Aceto TETD, Radothiram, Royal TMTD, Tetramethyl-thiram disulfid, Fernacol, Sadoplon 75, Tetramethylthiuram bisulfide, Tetrapom, Thioknock, Thirampa, Thiramum, Anles, Arasan-SF-X, Aules, Thimer, Panoram 75, Tetramethylthiuram disulphide, Tetramethylthiurane disulfide, Arasan 70, Arasan 75, Tersan 75, Thiram 75, Thiram 80, Spotrete-F, TMTDS, Arasan 70-S Red, Tetramethylthioperoxydicarbonic diamide, Methylthiuram disulfide, N,N-Tetramethylthiuram disulfide, Metiurac, Micropearls, Nomersan, Thianosan, Cunitex, Delsan, Metiur, Thimar, Teramethylthiuram disulfide, Tersantetramethyldiurane sulfide, Pol-Thiuram, Arasan 42-S, Tetramethylthiurum disulfide, Disulfure de tetramethylthiourame, Tetrathiuram disulphide, Tetramethylthiouram disulfide, Sranan-sf-X, Hy-Vic, Chipco thiram 75, Bis(dimethyl-thiocarbamoyl)-disulfid, Orac TMTD, Tetramethylthioramdisulfide, Tetramethyldiurane sulphite, Thiotox (fungicide), Disulfide, bis(dimethylthiocarbamoyl), Bis((dimethylamino)carbonothioyl) disulfide, Fermide 850, Tetramethyl thiuramdisulfide, Tetramethylthiocarbamoyldisulphide, Thiuramyl, Thylate, Tulisan, Attack, Methyl thiuramdisulfide, Bis(dimethylthiocarbamyl) disulfide, Tetramethyl thiurane disulfide, Bis(dimethyl thiocarbamoyl)disulfide, Thirame [INN-French], Thiramum [INN-Latin], Thiuram D, Disolfuro di tetrametiltiourame, Tetramethyl thiurane disulphide, Tetramethylenethiuram disulphide, N,N'-(Dithiodicarbonothioyl)bis(N-methylmethanamine), SQ 1489, RCRA waste number U244, Flo Pro T Seed Protectant, Tetramethylthiuram bisulphide, Tetramethylthiuran disulphide, Tetramethylthiurum disulphide, Tetramethyl thiuram disulfide, Caswell No. 856, alpha,alpha'-Dithiobis(dimethylthio)formamide, Thiotex, Thiurad, Thiuramin, Tirampa, Tiuramyl, Trametan, Tridipam, Tripomol, Tyradin, Tuads, Tutan, Vulkacit mtic, N,N,N',N'-Tetramethylthiuram disulfide, N,N-Tetramethylthiuram disulphide, Vulkacit thiuram, Thioperoxydicarbonic diamide, tetramethyl-, Thiuram M, Vulkacit TH, Tetramethylthioramdisulfide [Dutch], Vulcafor TMT, Vulcafor TMTD, Bis((dimethylamino)carbonothioyl) disulphide, FMC 2070, NSC-1771, Bis(dimethylthiocarbamoyl) disulphide, Tetramethyl-thiram disulfid [German], UNII-0D771IS0FH, Formamide, 1,1'-dithiobis(N,N-dimethylthio-, Zaprawa Nasienna T, [Me2NC(S)S]2, Vancida tm-95, Disulfuro di tetrametiltiourame, Arasan 42S, TUEX, CCRIS 1282, HSDB 863, Disolfuro di tetrametiltiourame [Italian], Disulfuro di tetrametiltiourame [Italian], Disulfure de tetramethylthiourame [French], C6H12N2S4, ENT 987, NSC1771, KUAZQDVKQLNFPE-UHFFFAOYSA-N, dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate, Bis(dimethyl-thiocarbamoyl)-disulfid [German], NSC 1771, VUAgT-I-4, EINECS 205-286-2, NSC 49512, NSC 59637, RCRA waste no. U244, EPA Pesticide Chemical Code 079801, NSC 622696, [disulfanediylbis(carbonothioylnitrilo)]tetramethane, BRN 1725821, Thiuram M rubber accelerator, AI3-00987, MLS000069752, MLS002702972, 0D771IS0FH, CHEBI:9495, Thiuram disulfide, tetramethyl-, Thiuram-M, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetramethyl-, bis[Dimethylthiocarbamyl] disulfide, NSC49512, CCG-35460, NSC622696, TNTD, NCGC00091563-01, SMR000059023, Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetramethyl-, [dithiobis(carbonothioylnitrilo)]tetramethane, DSSTox_CID_1332, DSSTox_RID_76087, .alpha.,.alpha.'-Dithiobis(dimethylthio)formamide, DSSTox_GSID_21332, Granuflo, N,N',N'-Tetramethylthiuram disulfide, TMT Disulfide, (dimethylamino){[(dimethylamino)thioxomethyl]disulfanyl}methane-1-thione, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetramethyl-, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N',N'-tetramethyl-, CAS-137-26-8, Formamide,1'-dithiobis(N,N-dimethylthio-, Bis[(dimethylamino)carbonothioyl] disulfide, Attack [Antifungal], NSC59637, Thiram [USAN:INN], WLN: 1N1 & YUS & SSYUS & N1 & 1, rhenogran, tiramo, Basultra, Betoxin, Tiradin, Accelerant T, Arasan m, Vulkazam S, Thiram [USAN:INN:ISO:BSI], Vanguard GF, Vancide TM, Akrochem TMTD, Perkacit TMTD, Vulkacit DTMT, Robac TMT, Thiram (Tmtd), Rezifilm (TN), Arasan 50 red, Spotrete WP 75, Vancide TM-95, Naftocit thiuram 16, Thiram [BSI:ISO], Spectrum_001687, Thiram (USAN/INN), Agrichem flowable thiram, AC1L1KDW, AC1Q7ETF, Spectrum2_001554, Spectrum3_001592, Spectrum4_000860, Spectrum5_001653, bmse000928, D02UVS, EC 205-286-2, NCIMech_000272, cid_5455, NCIOpen2_007854, SCHEMBL21144, BSPBio_003184, KBioGR_001499, KBioSS_002167, 4-04-00-00242 (Beilstein Handbook Reference), KSC491C8F, BIDD:ER0359, DivK1c_000741, SPECTRUM1503322, SPBio_001428, CHEMBL120563, DTXSID5021332, BDBM43362, CTK3J1182, HMS502F03, KBio1_000741, KBio2_002167, KBio2_004735, KBio2_007303, KBio3_002684, KUAZQDVKQLNFPE-UHFFFAOYSA-, ENT-987, MolPort-002-317-292, NINDS_000741, HMS1922A12, HMS2093E03, HMS2234B08, HMS3374C05, Pharmakon1600-01503322, Tetramethylthiuram disulfide, 97%, KS-00000Z7X, ZINC1532176, Thiram 10 microg/mL in Cyclohexane, Tox21_111150, Tox21_201569, Tox21_301102, LS-803, NSC-49512, NSC758454, SBB000804, STL264104, AKOS000120200, bis (dimethyl thiocarbamoyl) disulfide, Bis(dimethylaminothiocarbonyl)disulfide, Tox21_111150_1, alpha'-Dithiobis(dimethylthio)formamide, KS-5354, MCULE-4171536161, NSC-622696, NSC-758454, RL01641, RTR-004967, SQ-1489, IDI1_000741, QTL1_000082, TRA-0180716, NCGC00091563-02, NCGC00091563-03, NCGC00091563-04, NCGC00091563-05, NCGC00091563-06, NCGC00091563-07, NCGC00091563-08, NCGC00091563-09, NCGC00091563-10, NCGC00091563-12, NCGC00255002-01, NCGC00259118-01, AN-43793, CC-34914, CJ-24160, KB-61557, NCI60_001477, NCI60_006736, SC-18941, ST044501, SBI-0051813.P002, Tetramethylthiuram disulfide, 97% 100g, Thiram, PESTANAL(R), analytical standard, AB1002114, TR-004967, B0486, CS-0012858, FT-0083178, FT-0631799, 37T268, C11160, D06114, 26833-EP2280009A1, 26833-EP2305658A1, 26833-EP2314583A1, AB00052345_10, C-31381, SR-01000736911, J-006992, J-524968, SR-01000736911-2, Thiram, certified reference material, TraceCERT(R), BRD-K29254801-001-06-3, F0001-0468, TETRAMETHYLTHIOPEROXYDICARBONIC ACID [(H2N)C(S)]2S2, N,N-dimethyl[(dimethylcarbamothioyl)disulfanyl]carbothioamide, 1-(dimethylthiocarbamoyldisulfanyl)-N,N-dimethyl-methanethioamide, N,N-dimethylcarbamodithioic acid (dimethylthiocarbamoylthio) ester, InChI=1/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3, Bis(dimethylthiocarbamoyl) disulfide; Bis(dimethylthiocarbamyl) disulfide; Thiram, N(1),N(1),N(3),N(3)-tetramethyl-2-dithioperoxy-1,3-dithiodicarbonic diamide, N,N-dimethylcarbamodithioic acid [[dimethylamino(sulfanylidene)methyl]thio] ester, 1135443-08-1, 12680-07-8, 12680-62-5, 200889-05-0, 39456-80-9, 56645-31-9, 66173-72-6, 92481-09-9, 93196-73-7

ID: 1215

InChIKey: KUIXZSYWBHSYCN-UHFFFAOYSA-L
SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3NC4=CC(=CC=C4)S(=O)(=O)CCOS(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 17409
synonyms found at PubChem are:
Reactive Blue 19, 2580-78-1, Remazol brilliant blue R, Cavalite Brilliant Blue R, C.I. Reactive Blue 19, Remalan Brilliant Blue R, UNII-L51IMM9UP9, CI REACTIVE BLUE 19, CCRIS 3736, HSDB 5534, C.I. 61200, EINECS 219-949-9, CI Reactive Blue 19, disodium salt, Sodium 2-((3-((4-amino-9,10-dioxo-3-sulfonato-9,10-dihydroanthracen-1-yl)amino)phenyl)sulfonyl)ethyl sulfate, C.I. Reactive Blue 19, disodium salt, L51IMM9UP9, CI 61200, 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-4-(m-((2-hydroxyethyl)sulfonyl)anilino)-9,10-dioxo-, hydrogen sulfate (ester), disodium salt, 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-((3-((2-(sulfooxy)ethyl)sulfonyl)phenyl)amino)-, disodium salt, C.I.Reactive Blue 19, disodium 1-amino-9,10-dioxo-4-[3-(2-sulfonatooxyethylsulfonyl)anilino]anthracene-2-sulfonate, 2-(3-((4-Amino-9,10-dihydro-3-sulpho-9,10-dioxoanthracen-4-yl)amino)benzenesulphonyl)vinyl disodium sulphate, 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-4-(m-((2-hydroxyethyl)sulfonyl)anilino-9,10-dioxo-, hydrogen sulfate (ester), disodium salt, 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino]-, disodium salt, 2-anthracenesulfonicacid,1-amino-9,10-dihydro-9,10-dioxo-4-((3-((2-(sulfooxy), 2-anthracenesulfonicacid,1-amino-9,10-dihydro-9,10-dioxo-4-[[3-[[2-(sulfooxy), 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-((3-((2-(sulfooxy)ethyl)sulfonyl)phenyl)amino)-, sodium salt (1:2), 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10-dioxo-4-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino]-, sodium salt (1:2), disodium 1-amino-9,10-dioxo-4-[(3-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)amino]-9,10-dihydroanthracene-2-sulfonate, c.i.reactiveblue19, EC 219-949-9, SCHEMBL29532, 2-Anthracenesulfonic acid, 1-amino-9,10-dihydro-9,10- dioxo-4-[[3-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]amino ]-, disodium salt, AC1L29Y8, c.i.reactiveblue19(61200), c.i.reactiveblue19,disodiumsalt, DTXSID5025992, C22H16N2Na2O11S3, CTK8G2922, MolPort-003-959-464, KS-000026CM, GT9632, AKOS017345135, GS-6781, LS-1084, 2-(3-(4-amino-9,10-dihydro-3-sulpho-9,10-dioxoanthracen-4-yl)aminobenzenesulphonyl)vinyl) disodium sulphate, AK162142, AN-21714, T651, AX8238588, Remazol Brilliant Blue R, anthraquinone dye, ST24049203, W-109802, anilino)-9,10-dioxo-,hydrogensulfate(ester),disodiumsalt, anilino-9,10-dioxo-,hydrogensulfate(ester),disodiumsalt, 2-anthracenesulfonicacid,1-amino-9,10-dihydro-4-(m-((2-hydroxyethyl)sulfonyl), 110540-35-7, 122392-55-6, 12640-88-9, 1353580-23-0, 2-(3-(4-Amino-9,10-2H-3-sulpho-9,10-dioxoanthracen-4-yl)aminobenzenesulphonyl)vinyl) 2Na sulphate, 216383-13-0, 90598-99-5, 95145-50-9, 960305-71-9, dipotassium 1-amino-9,10-dioxo-4-({3-[2-(sulfonatooxy)ethanesulfonyl]phenyl}amino)anthracene-2-sulfonate, disodium 1-amino-9,10-dioxo-4-({3-[2-(sulfonatooxy)ethanesulfonyl]phenyl}amino)anthracene-2-sulfonate, disodium 1-amino-9,10-dioxo-4-({3-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-9,10-dihydroanthracene-2-sulfonate, disodium,1-amino-9,10-dioxo-4-[3-(2-sulfonatooxyethylsulfonyl)anilino]anthracene-2-sulfonate, disodium;1-amino-9,10-dioxo-4-[3-(2-sulfonatooxyethylsulfonyl)anilino]anthracene-2-sulfonate, sodium 2-(3-(4-amino-9,10-dioxo-3-sulfonato-9,10-dihydroanthracen-1-ylamino)phenylsulfonyl)ethyl sulfate, MFCD00001215, Remazol Brilliant Blue R (C.I. 61200)

ID: 1216

InChIKey: KUVIULQEHSCUHY-XYWKZLDCSA-N
SMILES: CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)Cl)O)C)C)OC(=O)CC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 21700
synonyms found at PubChem are:
BECLOMETHASONE DIPROPIONATE, Beclometasone dipropionate, Beconase, Beclovent, Vancenase, 5534-09-8, Beclazone, Becloforte, Beclomet, Beclorhinol, Propaderm, Sanasthmax, Sanasthmyl, Vanceril, Aerobec, Becloturmant, Beclacin, Entyderma, Korbutone, Respocort, Viarox, Rino-clenil, Clenil-A, Beclometasone 17,21-dipropionate, Aldecin, Alanase, Aldecina, Aldecine, Atomase, Beclate, Benconase, Rhinosol, Turbinal, Clenil, Spir, Beclocort Nasel, Beclomet Nasal, Propaderm Forte, Rhino Clenil, Inalone O, Inalone R, Qvar, QNASL, Beconase AQ, Qvar 80, Vanceril Double Strength, QVAR 40, CHEBI:3002, UNII-5B307S63B2, KUVIULQEHSCUHY-XYWKZLDCSA-N, SCH 18020W, EINECS 226-886-0, KW-053, 9-Chloro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, 5B307S63B2, 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, BECLOMETHASONE DIPROPIONATE MONOHYDRATE, Ventolair, (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate, 9-chloro-16beta-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate, Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)-, Pregna-1,4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-, 17,21-dipropionate, C28H37ClO7, Menaderm, Beclovent (TN), NCGC00094596-03, Vanceril (TN), CPD001233361, Beclazone 250, Prestwick_990, Qnasl (TN), AC1L2IWA, Beclometasone dipropionato, Prestwick0_000855, Prestwick1_000855, Prestwick2_000855, Prestwick3_000855, AC1Q62MZ, SCHEMBL6890, DSSTox_CID_28656, DSSTox_RID_82926, Propionic acid beclomethasone, DSSTox_GSID_48730, BSPBio_000869, MLS002154034, SPBio_002790, BPBio1_000957, GTPL5894, CHEMBL1200500, DTXSID3048730, CTK8F7938, Beclomethasone dipropionate (USP), MolPort-003-983-412, HMS1570L11, HMS2097L11, HMS2235O23, HMS3259H03, HMS3714L11, Beclometasone dipropionate (JP17), Beclomethasone dipropionate [USAN], 9-Chloro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)-, ZINC3938744, Tox21_113168, HY-13571A, MFCD00135613, s3078, AKOS015951275, AC-2159, API0001601, CCG-220855, CS-1503, DB00394, NC00610, Beclomethasone dipropionate [USAN:USP], NCGC00179392-01, AN-14214, SMR001233361, CAS-5534-09-8, AB1009261, LS-118439, B4464, ST24046007, C07813, D00689, W-5080, 32278-EP2281815A1, 32278-EP2295408A1, 32278-EP2301933A1, 32278-EP2305640A2, 32278-EP2311827A1, 534B098, BRD-K97810537-001-03-7, BRD-K97810537-001-13-6, Beclomethasone dipropionate, analytical standard, for drug analysis, Beclomethasone dipropionate, anhydrous, European Pharmacopoeia (EP) Reference Standard, Beclomethasone Dipropionate, Pharmaceutical Secondary Standard; Certified Reference Material, Beclomethasone dipropionate, United States Pharmacopeia (USP) Reference Standard, (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate, [(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate, [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate, 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate, 34135-07-4, 9-AE-11|A,17,21-EyoC>>u-16|A-(1/4)x>>uOEthcThorn-1,4- paragraph signthornI(c)-3,20- paragraph signthornI feminine-17,21- paragraph signthorn+/-uEao yen, 9-Chloro-11|A,17,21-trihydroxy-16|A-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, 9-Chloro-11beta, 17,21-trihydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard, Beclometasone dipropionate for system suitability, European Pharmacopoeia (EP) Reference Standard, Pregna-1-4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-,17,21-dipropionate

ID: 1217

InChIKey: KVAGRMDUXLYLAZ-ZGZXWHTRSA-N
SMILES: CC(C)/C(=C/1\C2[C@]([C@@H](OC1=O)C3=COC=C3)(C([C@H]([C@@]45[C@]26[C@@H]([C@]7(C(C8(CC7([C@]4([C@H]8CC(=O)OC)C)OC(O5)(O6)C)C)OC(=O)C(C)C)O)OC(=O)C)OC(=O)C)OC(=O)C)C)/O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 54721972
synonyms found at PubChem are:
BUSSEIN, SPECTRUM100006, CCG-39788, SDCCGMLS-0066359.P001, NCGC00179156-01, SR-05000002785, SR-05000002785-1

ID: 1218

InChIKey: KVNRDSLYCOJCRD-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(O1)C(=C(C=C2O)OC)CC=C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4643333
synonyms found at PubChem are:
HETEROPEUCENIN, METHYL ETHER, KBio2_003599, AC1NEJNQ, Spectrum_000551, SpecPlus_000042, Spectrum2_000345, Spectrum3_000096, Spectrum4_001370, Spectrum5_000020, BSPBio_001652, KBioGR_001640, KBioSS_001031, SPECTRUM100529, Heteropeucenin 7-methyl ether, DivK1c_006138, SPBio_000409, CHEMBL1355051, KBio1_001082, KBio2_001031, KBio2_006167, KBio3_000752, CCG-38620, NCGC00095427-01, NCGC00095427-02, NCGC00095427-03, NCGC00179116-01, SR-05000002525, SR-05000002525-1, BRD-K08745849-001-03-6, 5-hydroxy-7-methoxy-2-methyl-8-(3-methylbut-2-enyl)chromen-4-one

ID: 1219

InChIKey: KVOJTUXGYQVLAJ-UHFFFAOYSA-N
SMILES: CC1=CC(=O)OC2=CC(=C(C=C12)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5319502
synonyms found at PubChem are:
4-Methylesculetin, 529-84-0, 6,7-DIHYDROXY-4-METHYLCOUMARIN, 6,7-Dihydroxy-4-methyl-2H-chromen-2-one, Methylesculetin, 4-Methylaesculetin, 4-Methylesculetol, 4-Methyl-6,7-dihydroxycoumarin, 2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-methyl-, Coumarin, 6,7-dihydroxy-4-methyl-, 6,7-Dihydroxy-4-methyl-2H-benzopyran-2-one, NSC 11828, NSC 688807, UNII-132H8N0A91, EINECS 208-470-0, 6,7-dihydroxy-4-methylchromen-2-one, 6,7-Dihydroxy-4-methyl-chromen-2-one, BRN 0162550, AI3-18220, CHEMBL313244, KVOJTUXGYQVLAJ-UHFFFAOYSA-N, 6,7-Dihydroxy-4-methyl-2H-1-benzopyran-2-one, NSC11828, NSC688807, 132H8N0A91, NSC-688807, SR-01000389898, Spectrum_001029, SpecPlus_000495, Spectrum2_000617, Spectrum3_000592, Spectrum4_001864, Spectrum5_000428, AC1NSY77, Oprea1_739367, BSPBio_002064, KBioGR_002330, KBioSS_001509, 5-18-03-00231 (Beilstein Handbook Reference), DivK1c_006591, SCHEMBL409482, SPECTRUM1500729, SPBio_000554, DTXSID6060187, 4-methy1-6,7-dihydroxycoumarin, KBio1_001535, KBio2_001509, KBio2_004077, KBio2_006645, KBio3_001564, ZINC58125, MolPort-001-020-022, ALBB-015650, KS-000013XH, 7498AB, ANW-43466, BBL027618, BDBM50078820, CCG-38534, CM-899, NSC-11828, SBB057778, STL372185, AKOS003241110, GS-5460, MCULE-2984770490, SDCCGMLS-0066617.P001, NCGC00095628-01, NCGC00095628-02, NCGC00178836-01, AJ-09814, AN-45606, LS-55168, ZB002326, 4-methyl-6,7-bis(oxidanyl)chromen-2-one, KB-198916, TR-037421, 6,7-dihydroxy-4-methyl-1-benzopyran-2-one, EU-0066858, FT-0619082, M0766, R1156, ST45024832, A829333, I14-1655, SR-01000389898-1, SR-01000389898-2, W-200029, F1011-0383, InChI=1/C10H8O4/c1-5-2-10(13)14-9-4-8(12)7(11)3-6(5)9/h2-4,11-12H,1H

ID: 1220

InChIKey: KVQVEJPIQHNLTM-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C(=CO2)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4303260
synonyms found at PubChem are:
ANHYDROBRAZILIC ACID, KBio1_001382, 2-(7-methoxy-4-oxochromen-3-yl)acetic acid, 29107-21-9, Spectrum_000603, SpecPlus_000342, Spectrum2_000196, Spectrum3_000184, Spectrum4_001502, Spectrum5_000263, AC1N7J0R, BSPBio_001707, KBioGR_002163, KBioSS_001083, SPECTRUM200457, DivK1c_006438, SPBio_000151, CHEMBL3039171, CTK1A5415, KBio2_001083, KBio2_003651, KBio2_006219, KBio3_001207, DTXSID30401728, CHEBI:113533, CCG-38402, AKOS030552701, SDCCGMLS-0066377.P001, NCGC00095480-01, NCGC00095480-02, NCGC00179068-01, 4H-1-Benzopyran-3-aceticacid, 7-methoxy-4-oxo-, SR-05000002477, SR-05000002477-1, BRD-K78414110-001-02-8, BRD-K78414110-001-03-6

ID: 1221

InChIKey: KVRQGMOSZKPBNS-FMHLWDFHSA-N
SMILES: C[C@@]1(C[C@H]([C@]2([C@@H]1[C@@H](OC=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)OC(=O)/C=C/C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281542
synonyms found at PubChem are:
Harpagoside, 19210-12-9, UNII-8KGS1DC5ZU, 8KGS1DC5ZU, CHEBI:5625, SMR001233395, E-harpagoside, EINECS 242-881-6, AC1NQYLY, Prestwick3_000988, BSPBio_001055, MLS002154086, MLS002473324, SCHEMBL893387, BPBio1_001161, CHEMBL516702, MEGxp0_000469, Harpagoside, analytical standard, ACon0_000056, ACon1_000134, KVRQGMOSZKPBNS-FMHLWDFHSA-N, MolPort-001-740-640, HMS2098E17, HMS2231N12, ZINC8214398, AKOS015896715, LMPR0102070010, MCULE-8388168328, NCGC00179325-01, NCGC00179325-02, NCGC00179325-04, 4CN-1249, SC-19416, AB00513986, V0696, C09783, 210H129, I07-0170, Q-100231, BRD-K07996107-001-01-7, BRD-K07996107-001-03-3, Harpagoside, primary pharmaceutical reference standard, Harpagoside, European Pharmacopoeia (EP) Reference Standard, (1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl cinnamate, (1S-(1alpha,4aalpha,5alpha,7alpha(E),7aalpha))-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-((allyl-1-oxo-3-phenyl)oxy)cyclopenta(c)pyran-1-yl-beta-D-glucopyranoside, [(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate, b-D-Glucopyranoside,(1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl

ID: 1222

InChIKey: KVWNWTZZBKCOPM-UHFFFAOYSA-M
SMILES: CC[N+](C)(C)CC1=CC=CC=C1Br.CC1=CC=C(C=C1)S(=O)(=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6100
synonyms found at PubChem are:
Bretylium tosylate, 61-75-6, Bretylol, Bretylium tosilate, Ornid, Darenthin, Bretylate, Darentin, Bretylan, N-(2-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate, Bretylium p-toluenesulfonate, Bretylii tosilas, ASL-603, Tosilato de bretilio, Bretylium (tosylate), Tosilate de bretylium, Bretilio tosilato [DCIT], (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate, NSC 62164, UNII-78ZP3YR353, Bretylii tosilas [INN-Latin], Bretylium Tosylate In Dextrose 5%, Tosilate de bretylium [INN-French], Tosilato de bretilio [INN-Spanish], EINECS 200-516-8, Bretylium Tosylate In Plastic Container, 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate, Dimethylethyl-o-bromobenzylammonium-p-toluenesulphonate, N-Ethyl-N-o-bromobenzyl-N,N-dimethylammonium tosylate, MLS000028635, CHEBI:3173, ASL 603, 78ZP3YR353, CAS-61-75-6, NCGC00016119-02, SMR000058647, BRETYLIUM TOSYLATE IN DEXTROSE 5% IN PLASTIC CONTAINER, Bretylium tosilate (INN), Bretylium tosilate [INN], Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1), Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid, AMMONIUM, (o-BROMOBENZYL)ETHYLDIMETHYL-, p-TOLUENESULFONATE, Bretilio tosilato, NSC62164, SR-01000000254, Bretylium tosylate (USP), C11H17BrN.C7H7O3S, Bretylium tosylate [USAN:BAN], Bretylium tosylate [USAN:USP], bretyliume tosylate, Bretylol (TN), Opera_ID_1513, Lopac-B-8406, DSSTox_CID_2685, AC1L1LT0, AC1Q26DL, C18H24BrNO3S, DSSTox_RID_76691, DSSTox_GSID_22685, SCHEMBL40898, CHEMBL1095292, DTXSID1022685, CTK8B6650, MolPort-003-940-544, HMS1570N06, HMS2097N06, HMS2235I21, HMS3714N06, Tox21_110308, ANW-53884, HY-12961A, NSC-62164, RW1157, AKOS015842525, API0001757, CCG-204319, CS-5728, KS-0000012R, NCGC00016119-01, NCGC00016119-03, NCGC00016119-04, NCGC00024457-02, AK-81946, AN-23717, KB-48455, LS-16927, WLN: ER B1K2&1&1 &OSWR D1, Bretylium tosylate, >99% (TLC), powder, AB2000538, AX8118682, TC-061525, (2-bromobenzyl)ethyldimethylammonium tosylate, 4CH-007114, EU-0100224, FT-0080900, FT-0603258, ST24031295, V2113, B 8406, D00645, SR-01000000254-2, SR-01000000254-5, (2-bromobenzyl)ethyldimethylammonium toluene-4-sulfonate, N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate, N-(2-Bromobenzyl)-N,N-dimethylethaminium 4-methylbenzenesulfote, (2-bromophenyl)methyl-ethyl-dimethylazanium; 4-methylbenzenesulfonate, N-(2-Bromobenzyl)-N,N-dimethylethanaminium4-methylbenzenesulfonate, (2-bromophenyl)methyl-ethyl-dimethyl-ammonium; 4-methylbenzenesulfonate, 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methyl-benzenesulfontate, Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard, N-[(2-bromophenyl)methyl]-N,N-dimethylethanaminium 4-methylbenzenesulfonate, Benzenemethanaminium,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1)

ID: 1223

InChIKey: KVWWIYGFBYDJQC-UHFFFAOYSA-N
SMILES: CCCCCC1C(CCC1=O)CC(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 102861
synonyms found at PubChem are:
24851-98-7, Hedione, Methyl dihydrojasmonate, methyl 2-(3-oxo-2-pentylcyclopentyl)acetate, Kharismal, Cyclopentaneacetic acid, 3-oxo-2-pentyl-, methyl ester, Methyl (3-oxo-2-pentylcyclopentyl)acetate, FEMA No. 3408, Methyl 3-oxo-2-pentylcyclopentaneacetate, Methyl (2-pentyl-3-oxocyclopentyl)acetate, EINECS 246-495-9, Methyl 3-oxo-2-pentyl-cyclopentaneacetate, KVWWIYGFBYDJQC-UHFFFAOYSA-N, DIHYDROJASMONIC ACID, METHYL ESTER, DSSTox_CID_9325, DSSTox_RID_78763, DSSTox_GSID_29325, 128087-96-7, 2-Amylcyclopentan-1-one-3-acetic Acid Methyl Ester, W-107278, CAS-24851-98-7, methyl 2-(3-oxo-2-pentyl-cyclopentyl)acetate, Cepionate, Cyclopentaneacetic acid, 3-oxo-2-pentyl-, methyl ester, (1R,2R)-, Hedione(MDJ), methyl dihydro jasmonate extra EPI (CIS), Spectrum_001583, methyl dihydro jasmonate, AC1L2TPV, Spectrum2_000558, Spectrum3_001924, Spectrum4_001758, Spectrum5_000616, Dihydrojasmonic acid methyl, EC 246-495-9, AC1Q6DI3, BSPBio_003524, KBioGR_002236, KBioSS_002063, MLS002696002, SCHEMBL113649, SPECTRUM1504910, SPBio_000635, CYC017, CHEMBL1530328, DTXSID2029325, CTK8H8936, KBio2_002063, KBio2_004631, KBio2_007199, KBio3_002748, MolPort-002-506-946, HMS1617K17, BB_NC-00203, Tox21_202172, Tox21_303588, BBL009815, CCG-38726, FD7202, STK072613, AKOS001683947, DS-6422, MCULE-7597345136, SDCCGMLS-0066789.P001, KS-0000020U, methyl 3-oxo-2-pentylcyclopentylacetate, methyl 2-pentyl-3-oxo-cyclopentylacetate, NCGC00095846-01, NCGC00095846-02, NCGC00095846-03, NCGC00257324-01, NCGC00259721-01, AK114175, AN-18724, AN-18887, LS-57824, SMR000387079, AX8045218, KB-255052, Methyl2-(3-oxo-2-pentylcyclopentyl)acetate, EU-0083698, FT-0624961, Methyl 3-Oxo-2-pentyl-1-cyclopentaneacetate, UNM000000712401, SR-05000002474, SR-05000002474-1, 3-oxo-2-pentyl-cyclopentane-acetic acid methyl ester, Methyl dihydrojasmonate, mixture of cis and trans, >=96%, FG, Methyl dihydrojasmonate, mixture of cis and trans, analytical standard

ID: 1224

InChIKey: KWGKDLIKAYFUFQ-UHFFFAOYSA-M
SMILES: [Li+].[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 24016
synonyms found at PubChem are:
LITHIUM CHLORIDE, 7447-41-8, Lithiumchloride, Lithium chloride (LiCl), LiCl, chlorure de lithium, Chlorku litu, chlorolithium, Lithiumchlorid, Chlorku litu [Polish], Luthium chloride, Chlorure de lithium [French], CCRIS 5924, UNII-G4962QA067, HSDB 4281, EINECS 231-212-3, lithium(1+) ion chloride, NSC 327172, CHEMBL69710, CHEBI:48607, NSC327172, G4962QA067, ClLi, lithim chloride, lithii chloridum, Lithium chloride, anhydrous, chunks, 99.99% trace metals basis, Lithium Cholride, cloruro de litio, LithoTab chloride, Lithium Chloride Salt, Lithium chloride,crystal, Lithium chloride solution, Lithium chloride,anhydrous, Lopac-L-4408, D07WXT, MolMap_000071, WLN: LI G, EC 231-212-3, AC1L8V4Y, AC1Q1U4K, LithiumChlorideGr(Anhydrous), Lopac0_000604, LITHIUM CHLORIDE, ACS, KSC492I6F, Lithium chloride 1 M solution, Lithium chloride, ACS reagent, DTXSID2025509, CTK3J2462, KS-00000EUY, KWGKDLIKAYFUFQ-UHFFFAOYSA-M, MolPort-000-156-705, HMS3261J10, Tox21_500604, ANW-36491, MFCD00011078, AKOS015902822, AKOS015950647, AKOS024438070, CCG-204693, lithium chloride, gamma irradiated, 8m, LP00604, LS-1644, NSC-327172, RTR-024082, TRA-0189435, Lithium chloride, ACS reagent, >=99%, Lithium chloride, ReagentPlus(R), 99%, NCGC00015607-01, NCGC00015607-02, NCGC00015607-03, NCGC00015607-04, NCGC00093980-01, NCGC00093980-02, NCGC00261289-01, SC-46832, SC-65521, Lithium chloride solution, 1 M in ethanol, Lithium chloride solution, 2 M in ethanol, Lithium Chloride, 40 % solution in water, Lithium chloride, anhydrous, 98% 100g, Lithium chloride, Vetec(TM) reagent grade, AB1002933, KB-297204, TR-024082, EU-0100604, FT-0627896, L0204, L0222, W8215, LITHIUM CHLORIDE, ANHYDROUS, 99.65%, L 4408, Lithium chloride, SAJ first grade, >=98.0%, Lithium chloride, for molecular biology, >=99%, Lithium chloride, SAJ special grade, >=99.0%, A838146, Lithium chloride, BioXtra, >=99.0% (titration), SR-01000076252, SR-01000076252-1, Electrolyte solution, nonaqueous, 2 M LiCl in ethanol, I14-19628, Lithium chloride solution, 1 M in glacial acetic acid, Lithium chloride, powder, >=99.99% trace metals basis, Z1741960146, Electrolyte solution, nonaqueous, LiCl in ethanol (saturated), Lithium chloride solution, 0.5 M in anhydrous tetrahydrofuran, Lithium chloride solution, 8 M, for molecular biology, >=99%, Lithium chloride, puriss. p.a., anhydrous, >=99.0% (AT), Lithium chloride solution, 1 M in 1,3-dimethyl-2-imidazolidinone, Lithium chloride, anhydrous, beads, -10 mesh, >=99.9% trace metals basis, Lithium chloride, anhydrous, beads, -10 mesh, 99.998% trace metals basis, Lithium chloride, puriss. p.a., ACS reagent, anhydrous, >=99.0% (AT), Lithium chloride, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%, Lithium chloride, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%, Lithium chloride, BioUltra, for molecular biology, anhydrous, >=99.0% (AT), 1220508-63-3, 1309791-76-1, 404596-80-1, Lithium atomic spectroscopy standard concentrate 1.00 g Li, 1.00 g/L, for 1 l standard solution, analytical standard, Lithium standard solution, suitable for atomic absorption spectrometry, 1 mg/mL Li, 1000 ppm Li

ID: 1225

InChIKey: KWTPHNVUAVFKGB-UHFFFAOYSA-N
SMILES: CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 173870
synonyms found at PubChem are:
SKF-75670 hydrobromide, SKF 75670 hydrobromide, 62717-63-9, Skf 75670, 7,8-dihydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, SK&F 75670, SK&F-75670, AC1L5AM5, MLS002172465, CHEMBL1256698, SCHEMBL11707024, CTK2F4318, AKOS030549460, API0007827, LP01087, NCGC00094362-01, SMR001254096, EU-0101087, S 2941, SKF-75670 hydrobromide, >98% (HPLC), solid, SR-01000076127, SR-01000076127-2, 3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-3-methyl-1-phenyl-, hydrobromide, 4-methyl-2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol hydrobromide

ID: 1226

InChIKey: KXDAEFPNCMNJSK-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2331
synonyms found at PubChem are:
Benzamide, 55-21-0, Benzoylamide, Benzoic acid amide, Phenylcarboxyamide, Phenylcarboxamide, Benzenecarboxamide, Amid kyseliny benzoove, Amid kyseliny benzoove [Czech], NSC 3114, Phenyl Carboxyamide, CCRIS 4594, HSDB 6360, BENZOIC ACID,AMIDE, EINECS 200-227-7, UNII-6X80438640, BRN 0385876, AI3-01031, CHEMBL267373, CHEBI:28179, KXDAEFPNCMNJSK-UHFFFAOYSA-N, 27208-38-4, 6X80438640, benzimide, N-benzoylamine, benzoyl nitrogen, Phenyl carboxamide, benzene carboxamide, Benzamide, 99%, AC1L1DFU, WLN: ZVR, benzene carboximidoic acid, PhC(O)NH2, Lopac-B-2009, ACMC-1AZ9T, DSSTox_CID_1709, bmse000668, PhC(=O)NH2, DSSTox_RID_76288, DSSTox_GSID_21709, Lopac0_000160, SCHEMBL16352, 4-09-00-00725 (Beilstein Handbook Reference), benzamide (ACD/Name 4.0), KSC175C0F, MLS000069472, Benzamide, p.a., 98.0%, ARONIS003511, DTXSID0021709, KS-00000FOV, KS-00003WHQ, NSC3114, MolPort-001-497-861, YSKVTRZUSMWAQJ-UHFFFAOYSA-N, HMS2231M11, HMS3260O22, HMS3371I16, ZINC152996, CS-Z0019, NSC-3114, Tox21_200621, Tox21_500160, ANW-32259, BDBM50106187, MFCD00007968, s4715, SBB058198, STK069333, AKOS000118773, CCG-204255, LP00160, LS-1353, MCULE-2811211507, RP19412, RTC-010676, CAS-55-21-0, Benzamide, purum, >=98.0% (HPLC), NCGC00015142-01, NCGC00015142-02, NCGC00015142-03, NCGC00015142-04, NCGC00015142-05, NCGC00015142-06, NCGC00091355-01, NCGC00091355-02, NCGC00091355-03, NCGC00258175-01, NCGC00260845-01, 4CN-0762, AJ-12870, AN-24423, BP-21224, CJ-01214, DS-17194, KB-47506, SC-26846, SMR000059089, ZB005314, Benzamide, Vetec(TM) reagent grade, 98%, ST2412632, B0012, B0220, EU-0100160, FT-0622630, FT-0622631, ST45040306, AZ0001-0025, B 2009, Benzamide, purified by sublimation, >=99.5%, C09815, M-4040, 12078-EP2272827A1, 12078-EP2275469A1, 12078-EP2284157A1, 12078-EP2284169A1, 12078-EP2287161A1, 12078-EP2287162A1, 12078-EP2287940A1, 12078-EP2289894A2, 12078-EP2289965A1, 12078-EP2292593A2, 12078-EP2295061A1, 12078-EP2295402A2, 12078-EP2295413A1, 12078-EP2295421A1, 12078-EP2295424A1, 12078-EP2295550A2, 12078-EP2298076A1, 12078-EP2298077A1, 12078-EP2298731A1, 12078-EP2298828A1, 12078-EP2300455A2, 12078-EP2301353A1, 12078-EP2301929A1, 12078-EP2301935A1, 12078-EP2301983A1, 12078-EP2305031A1, 12078-EP2305034A1, 12078-EP2305035A1, 12078-EP2305662A1, 12078-EP2305674A1, 12078-EP2305687A1, 12078-EP2308848A1, 12078-EP2308858A1, 12078-EP2311494A1, 12078-EP2314583A1, 12078-EP2314585A1, 12078-EP2316825A1, 12078-EP2316831A1, 12078-EP2371810A1, 74166-EP2308857A1, A830526, SR-01000075601, I01-6590, SR-01000075601-1, Benzamide, zone-refined, purified by sublimation, 99.9%, F3145-2903, InChI=1/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9, Sulfabenzamide|Sulfabenzid|Sulfabenzide|Sulfabenzoylamide|N-Sulfamylbenzamide

ID: 1227

InChIKey: KXEBLAPZMOQCKO-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68624
synonyms found at PubChem are:
Lomefloxacin hydrochloride, 98079-52-8, Maxaquin, Lomefloxacin HCl, Okacyn, Bareon, Uniquin, Ny-198, Mazaquin, SC-47111, Lomefloxacin (hydrochloride), NY 198, CCRIS 2581, 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, Lomefloxacin hydrochloride [USAN:JAN], CHEBI:6518, Lomefloxacin hydrochloride (Maxaquin), MFCD00214312, Maxaquin (TN), L-6500, DSSTox_CID_25527, DSSTox_RID_80931, DSSTox_GSID_45527, (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride, Logiflox, Okacin, 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, (+-)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride, 3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride, 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride, (+-)-, SR-01000075959, Lomebact, Maxaquine, C17H19F2N3O3.ClH, 1-ethyl-6,8-bis(fluoranyl)-7-(3-methylpiperazin-1-yl)-4-oxidanylidene-quinoline-3-carboxylic acid hydrochloride, 1-ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride, 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride, Prestwick_581, PubChem23948, 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride, 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid hydrochloride, NCGC00016964-01, NCGC00016964-02, AC1Q3CB3, CAS-98079-52-8, CHEMBL1728, Lomefloxacin HCl (Maxaquin), Lomefloxacin monohydrochloride, SCHEMBL42051, C17H20ClF2N3O3, SPECTRUM1502037, C17H19F2N3O3.HCl, AC1L2A47, DTXSID2045527, MolPort-003-666-401, HMS1568P17, HMS1921F20, Pharmakon1600-01502037, 98079-51-7 (Parent), BCP12636, HY-B0455, Tox21_110716, Tox21_113154, Tox21_500678, 2521AH, BG0239, CCG-39698, GA2013, NSC758168, s2539, AKOS015895388, Tox21_110716_1, API0005240, CM14476, CM14477, CS-2566, KS-1238, Lomefloxacin hydrochloride (JAN/USAN), LP00678, NSC-758168, NCGC00015603-08, NCGC00094038-01, NCGC00094038-02, NCGC00094038-03, NCGC00261363-01, AK-51350, AN-34635, BR-51350, CC-30023, H534, AB1009378, AX8136641, LS-141572, EU-0100678, FT-0630997, L0216, ST24027089, C08053, D00873, L 2906, M-7526, 079L528, A845801, A845802, C-21486, I06-0638, SR-01000075959-1, SR-01000075959-5, Lomefloxacin monohydrochloride, Antibiotic for Culture Media Use Only, 1-ethyl-6,8-difluor-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydrochinolin-3-carbons, 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid hydrochloride, KS-00000GHY, MolPort-028-751-487, AKOS025117338, AB0175096, 3-Quinolinecarboxylic acid,1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-,monohydrochloride

ID: 1228

InChIKey: KXFFLWDYUNIJNU-BFUOFWGJSA-N
SMILES: COC1=CC2=C(C=C1)[C@@H]([C@@H](CO2)CC3=CC(=C(C=C3)OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708784
synonyms found at PubChem are:
TETRAHYDROSAPPANONE A TRIMETHYL ETHER, KBio2_007328, Spectrum_001712, SpecPlus_000812, AC1O8FOT, Spectrum2_001920, Spectrum3_001722, Spectrum4_001675, Spectrum5_000609, BSPBio_003364, KBioGR_002229, KBioSS_002192, DivK1c_006908, SPECTRUM1600480, SPBio_001920, CHEMBL3039024, KBio1_001852, KBio2_002192, KBio2_004760, KBio3_002584, CCG-38487, SDCCGMLS-0066852.P001, NCGC00178116-01, (3R,4R)-3-[(3,4-dimethoxyphenyl)methyl]-7-methoxy-3,4-dihydro-2H-chromen-4-ol

ID: 1229

InChIKey: KXFFLWDYUNIJNU-YJYMSZOUSA-N
SMILES: COC1=CC2=C(C=C1)[C@H]([C@@H](CO2)CC3=CC(=C(C=C3)OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708683
synonyms found at PubChem are:
3-DESHYDROXYSAPPANOL TRIMETHYL ETHER, SR-05000002592, Spectrum_001469, SpecPlus_000449, AC1O8FJA, Spectrum2_001630, Spectrum3_000986, Spectrum4_001112, Spectrum5_001787, BSPBio_002651, KBioGR_001584, KBioSS_001949, DivK1c_006545, SPECTRUM1504036, SPBio_001699, CHEMBL3039115, KBio1_001489, KBio2_001949, KBio2_004517, KBio2_007085, KBio3_001871, CHEBI:109552, CCG-38750, SDCCGMLS-0066763.P001, NCGC00178550-01, SR-05000002592-1, SR-05000002592-2, (3R,4S)-3-[(3,4-dimethoxyphenyl)methyl]-7-methoxy-3,4-dihydro-2H-chromen-4-ol

ID: 1230

InChIKey: KXGVEGMKQFWNSR-WFTUMUMQSA-N
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5283833
synonyms found at PubChem are:
Allodeoxycholic acid, 5alpha-Deoxycholic acid, 3alpha,12alpha-Dihydroxy-5alpha-cholan-24-oic Acid, Allodeoxycholate, 3alpha,12alpha-Dihydroxy-5alpha-cholanoic acid, 1912-55-6, 3a,12a-Dihydroxy-5a-cholanoic acid, AC1NR34X, (3ALPHA,5ALPHA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, SCHEMBL20204259, CHEBI:81276, ZINC3918157, LMST04010044, C17687, (4R)-4-[(3R,5S,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

ID: 1231

InChIKey: KXPXJGYSEPEXMF-WYHSTMEOSA-N
SMILES: CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6852406
synonyms found at PubChem are:
Hyoscine hydrochloride, Scopolamine hydrochloride, (-)-Scopolamine hydrochloride, UNII-Q2P66EIP1F, 55-16-3, Q2P66EIP1F, MLS000069776, Scopolamine, hydrochloride, (-)-HYOSCINE HYDROCHLORIDE, SMR000058730, EINECS 200-225-6, Chlorhydrate de scopolamine [French], Chlorhydrate de scopolamine, Opera_ID_355, DSSTox_CID_24692, DSSTox_RID_80401, DSSTox_GSID_44692, MLS001076329, MLS002695952, SCHEMBL219719, CHEMBL1530287, DTXSID6044692, Benzeneacetic acid, alpha-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(sup 2,4))non-7-yl ester, hydrochloride, (7(S)-(1-alpha,2-beta,4-beta,5-alpha,7-beta))-, SCOPINE TROPATE HYDROCHLORIDE, Tox21_302226, 6403AF, AB02336, API0013020, CCG-220877, CAS-55-16-3, NCGC00256292-01, (-)-Scopolamine hydrochloride, analytical standard, 058H096, (-)-Scopolamine hydrochloride, >=90% (HPLC), powder, 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, 6-beta,7-beta-epoxy-, (-)-tropate (ester), HCl, (8CI)

ID: 1232

InChIKey: KYBLAIAGFNCVHL-PMVHANJISA-N
SMILES: C[C@]12CC[C@@H]([C@@H]1CC[C@@]3([C@@H]2CC[C@H]4[C@]3(C[C@@H]([C@@H]5[C@@]4(CCCC5(C)C)C)O)C)C)C(C)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 159931
synonyms found at PubChem are:
Zeorin, 22570-53-2, A'-Neogammacerane-6,22-diol, (6alpha)-, Zeorin, Zeorine, AC1L4MR5, SCHEMBL167009, (6alpha)-hopane-6,22-diol, CHEBI:67966, MolPort-035-706-323, ZINC5705858, AKOS032948158, 4CN-0203, A/'-Neogammacerane-6,22-diol, (6alpha)-, W2398, A22536, (3S,3aS,5aR,5bR,7S,7aS,11aR,11bR,13aR,13bS)-3-(1-hydroxy-1-methyl-ethyl)-5a,5b,8,8,11a,13b-hexamethyl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysen-7-ol, (3S,3aS,5aR,5bR,7S,7aS,11aR,11bR,13aR,13bS)-3-(2-hydroxypropan-2-yl)-5a,5b,8,8,11a,13b-hexamethyl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysen-7-ol, (6S,9S,20S,1R,2R,14R)-6-(1-Hydroxy-isopropyl)-1,2,9,14,18,18-hexamethylpentacyclo[11.8.0.0<2,10>.0<5,9>.0<14,19>]henicosan-20-ol

ID: 1233

InChIKey: KYGZCKSPAKDVKC-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4628
synonyms found at PubChem are:
oxolinic acid, 14698-29-4, Nidantin, Dioxacin, Emyrenil, Prodoxal, Prodoxol, Gramurin, Oksaren, Oxolinic, Ossian, Uroxol, Utibid, Uritrate, Urotrate, Oxoboi, Pietil, Starner, Ultibid, Acido oxolinico, Acide oxolinique, Uro-alvar, Acidum oxolinicum, Cistopax, Orthurine, Tiurasin, Acido ossolico, 5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid, NSC-110364, Urinox, Acido ossolico [DCIT], 1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid, UNII-L0A22B22FT, 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid, W 4565, NSC 110364, Acide oxolinique [INN-French], Acido oxolinico [INN-Spanish], Acidum oxolinicum [INN-Latin], CCRIS 6301, HSDB 3243, 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid, 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid, EINECS 238-750-8, BRN 0620635, 1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-, L0A22B22FT, C13H11NO5, 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid, CHEBI:138856, KYGZCKSPAKDVKC-UHFFFAOYSA-N, S-0208, 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-, NSC110364, NCGC00015762-06, CAS-14698-29-4, DSSTox_CID_1089, DSSTox_RID_75935, DSSTox_GSID_21089, W-108119, 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-ethyl-8-oxo-5-hydro-2H-1,3-dioxoleno[4,5-g]quinoline-7-carboxylic acid, SR-01000076042, Inoxyl, Oxolinic acid [USAN:BAN:INN], Oxolinic acid [USAN:INN:BAN], Aqualinic (TN), Prestwick_629, Spectrum_001397, AC1L1ILD, Prestwick0_000193, Prestwick1_000193, Prestwick2_000193, Prestwick3_000193, Spectrum2_000933, Spectrum3_001490, Spectrum4_000073, Spectrum5_001176, Lopac-O-0877, D00MAN, D0O7CL, AC1Q6E0J, Oxolinic acid (USAN/INN), Lopac0_000952, Oprea1_169598, SCHEMBL24445, BSPBio_000145, BSPBio_003079, KBioGR_000625, KBioSS_001877, MLS000028501, DivK1c_000659, SPECTRUM1502030, SPBio_000866, SPBio_002066, BPBio1_000161, CHEMBL416755, ZINC1875, Jsp002720, DTXSID1021089, HMS502A21, KBio1_000659, KBio2_001877, KBio2_004445, KBio2_007013, KBio3_002579, KS-00000GUT, AOB5349, MolPort-000-885-505, NINDS_000659, HMS1568H07, HMS1921F12, HMS2092P09, HMS2095H07, HMS3262P06, HMS3712H07, Oxolinic acid, analytical standard, Pharmakon1600-01502030, Oxolinic acid, quinolone antibiotic, ACT03284, GRC-6127, GRC-6211, HY-B1002, Tox21_110216, Tox21_202787, Tox21_500952, 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]chinolin-7-carbons, BBL009934, BN0853, CCG-39666, GA2313, MFCD00056775, NSC758177, s4537, SBB012469, STK801351, AKOS000282622, Tox21_110216_1, API0003716, CS-4499, LP00952, LS-7635, MCULE-2131347036, NSC-758177, IDI1_000659, NCGC00015762-01, NCGC00015762-02, NCGC00015762-03, NCGC00015762-04, NCGC00015762-05, NCGC00015762-07, NCGC00015762-08, NCGC00015762-09, NCGC00015762-10, NCGC00015762-11, NCGC00015762-13, NCGC00093361-02, NCGC00093361-03, NCGC00093361-04, NCGC00093361-05, NCGC00260333-01, NCGC00261637-01, AJ-08105, AK117020, AN-17428, AS-12087, CC-33419, SMR000058314, ST067125, SBI-0050926.P003, TRPV1 antagonists (pain), Glenmark/Lilly, AB1009279, AX8014601, DB-042865, KB-245869, EU-0100952, FT-0637128, ST24029466, T7411, TRPV1 antagonists (asthma), Glenmark/Lilly, VU0243182-3, C11342, D02301, O 0877, WLN: T C566 DO FO JN MV EHJ J2 LVQ, 698O294, C-16314, TRPV1 antagonists (incontinence), Glenmark/Lilly, I14-7471, SR-01000076042-1, SR-01000076042-4, SR-01000076042-6, BRD-K73394555-001-08-6, 5-Ethyl-5,3-dioxolo[4,5-g]quinoline-7-carboxylic acid, F3351-0487, 1-Ethyl-1,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid, Oxolinic acid, European Pharmacopoeia (EP) Reference Standard, 1,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-, 1.4-Dihydro-1-ethyl-6,7-methylenedioxy-4-oxoquinoline-3-carboxylic acid, 5-Ethy1-5,8-dihydro-8-oxo-1,3-dioxolo[4,5]quinoline-7-carboxylic acid, 5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylicacid, Transient receptor potential vanilloid sub-family 1 (pain), Glenmark/ Lilly, 5-ETHYL-8-OXO-2H,5H,8H-[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID, 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid #, Vanilloid receptor VR1 antagonists (incontinence/pain/asthma), Glenmark/Lilly, W-4565; 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid, InChI=1/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17

ID: 1234

InChIKey: KYHQZNGJUGFTGR-UHFFFAOYSA-N
SMILES: CC(CN1C=NC2=C1C(=O)N(C(=O)N2C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4977
synonyms found at PubChem are:
proxyphylline, 603-00-9, Proxiphylline, Purophyllin, Monophylline, Spasmolysin, Sanwaphyllin, Brontyl, Sigophyl, Theoden, Thean, Theon, Oxypropyltheophylline, 7-(2-Hydroxypropyl)theophylline, Proxy-Retardoral, Hydroxypropyltheophylline, Proxiphyllinum, 2-Hydroxypropyl-7-theophylline, 7-(beta-Hydroxypropyl)theophylline, Theophylline, 7-(2-hydroxypropyl)-, Proxylphylline, Proxyphyline, beta-Oxypropyltheophyllin, 1,3-Dimethyl-7-(2-hydroxypropyl)xanthine, Proxifilina [INN-Spanish], Proxyphyllinum [INN-Latin], NSC 163343, Proxyphylline [INN:BAN:JAN], EINECS 210-028-7, CHEMBL37390, MLS000069521, .beta.-Hydroxypropyltheophylline, MT, 7-(beta-Hydroxypropyl)-1,3-dimethylxanthine, 7-(2-Hydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, 3,7-Dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-, 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-, 7-(.beta.-Hydroxypropyl)theophylline, SMR000058629, 7-(2-Hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione, DSSTox_CID_3536, 7-(.beta.-Hydroxypropyl)-1,3-dimethylxanthine, DSSTox_RID_77068, DSSTox_GSID_23536, 7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione, W-105265, 1,3-Dimethyl-7-(2-hydroxypropyl)-2,6-dioxopurine], Proxifilina, Proxyphyllinum, proxyphylline(jan), Proxyfylline, Spantin, 7-(2-hydroxypropyl)-1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, Monophyllin (TN), NCGC00016521-01, CAS-603-00-9, AC1L1JCF, AC1Q2BVZ, Opera_ID_1170, Prestwick0_000890, Prestwick1_000890, Prestwick2_000890, Prestwick3_000890, Proxyphylline (JAN/INN), AC1Q2BW0, AC1Q6LE8, beta-Hydroxypropyltheophylline, SCHEMBL35569, BSPBio_000680, SPBio_002899, 7-(-Hydroxypropyl)theophylline, 7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione, BPBio1_000748, DTXSID5023536, CHEBI:32070, KYHQZNGJUGFTGR-UHFFFAOYSA-N, MolPort-001-832-763, HMS1570B22, HMS2097B22, HMS2233E08, HMS3371A07, Pharmakon1600-01505915, HY-B1742, KS-000017UY, Tox21_110471, BDBM50028190, KM0393, NSC163343, NSC759279, PDSP1_001132, PDSP2_001116, SBB058155, 3,3-dimethyl-1H-purine-2,6-dione, AKOS015967318, Tox21_110471_1, CCG-213993, CS-7727, MCULE-2304226036, NSC-163343, NSC-759279, NCGC00018121-02, NCGC00018121-03, NCGC00018121-07, NCGC00179479-01, AN-46325, AS-11774, 7-(2-hydroxypropyl)-1,3-dimethylxanthine, 7-(beta-HYDROXYPROPYL)-THEOPHYLLINE, SBI-0207057.P001, AX8040403, LS-149606, AB00513948, FT-0603485, ST50409303, D01771, AB00384297_13, SR-01000003009, SR-01000003009-2, 7-(2-hydroxypropyl)-1,3-dimethyl-purine-2,6-dione, BRD-A28887267-001-03-7, 1,3-DIMETHYL-7-(2-HYDROXYPROPYL)-2,6-DIOXOPURINE, 1H-Purine-2, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-, 1H-Purine-2, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-, Proxyphylline, European Pharmacopoeia (EP) Reference Standard, 7-(2-hydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, 7-(2-Hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione #, 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl- (9CI), 7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(Proxyphylline)

ID: 1235

InChIKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4122
synonyms found at PubChem are:
nocodazole, 31430-18-9, Oncodazole, R 17934, Nocodazolum, Nocidazole, Nocodazol, NSC 238159, Nocodazole [USAN:INN], Nocodazol [INN-Spanish], Nocodazolum [INN-Latin], R 17,934, UNII-SH1WY3R615, Methyl 5-(2-thenoyl)-2-benzimidazolecarbamate, Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate, NSC-238159, Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate, R-17934, C14H11N3O3S, EINECS 250-626-5, N-(5-(2-Thenoyl)-2-benzimidazolyl)carbamic acid methyl ester, NSC238159, R17934, Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate, 2-Benzimidazolecarbamic acid, 5-(2-thienylcarbonyl)-, methyl ester, NSC 238 159, CHEMBL9514, MLS001164242, SH1WY3R615, 2-Benzimidazolecarbamic acid, 5-(2-thenoyl)-, methyl ester, CHEBI:34892, Methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)carbamate, methyl (5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate, Methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate, Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester, IN1188, API0003615, NCGC00015647-05, SMR000326904, CAS-31430-18-9, [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester, Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)-, methyl ester, Carbamic acid, [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester, Methyl 5-(2-thienoyl)-2-benzimidazolecarbamate, DSSTox_CID_11800, DSSTox_RID_78890, DSSTox_GSID_31800, W-202288, 2-Benzimidazolecarbamic acid, 5-(2-thienoyl)-, methyl ester, Methyl [5-(2-thienylcarbonyl)-1H- benzimidazol-2-yl]carbamate, Methyl-[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamate, N-(5-(2-Thienoyl)-2-benzimidazolyl)carbamic acid methyl ester, SR-01000075979, Nococazole, Methyl(5-(2-thienylcarbonyl))-1H-benzimidazole-2-yl carbamate, Methyl[5-(2-thienylcarbonyl)]-1H-benzimidazole-2-yl carbamate, N-[5-(2-Thenoyl)-2-benzimidazolyl]carbamic acid methyl ester, N-[5-(2-Thienoyl)-2-benzimidazolyl]carbamic acid methyl ester, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester, Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester (9CI), Carbamic acid, [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester (9CI), NZO, Prestwick_359, Tocris-1228, 3ee2, AC1L1HGM, Nocodazole (USAN/INN), Prestwick0_000100, Prestwick1_000100, Prestwick2_000100, Prestwick3_000100, Spectrum3_001768, Spectrum4_001060, Lopac-M-1404, nocodazole and R17934, ChemDiv1_000089, Probes1_000012, Probes1_000176, Probes2_000086, Probes2_000148, UPCMLD-DP111, Cambridge id 5175348, cid_4122, SCHEMBL9477, Lopac0_000733, Oprea1_483899, Oprea1_741554, BSPBio_000060, BSPBio_000982, BSPBio_003235, CBDivE_004971, CBDivE_008428, JSPY-st000005, KBioGR_000322, KBioGR_001360, KBioSS_000322, MLS000860046, BIDD:GT0494, SPECTRUM1503266, SPBio_001999, BPBio1_000066, DTXSID9031800, UPCMLD-DP111:001, BCBcMAP01_000161, BDBM97233, CTK8G1974, HMS587E01, KBio2_000322, KBio2_002890, KBio2_005458, KBio3_000643, KBio3_000644, KBio3_002735, ZINC56509, AOB6196, KYRVNWMVYQXFEU-UHFFFAOYSA-N, MolPort-000-828-268, MolPort-001-889-558, Bio1_000461, Bio1_000950, Bio1_001439, Bio2_000331, Bio2_000811, HMS1362B03, HMS1568C22, HMS1792B03, HMS1922O09, HMS1990B03, HMS2094G13, HMS2095C22, HMS2235E18, HMS3262C08, HMS3267F03, HMS3403B03, HMS3604E13, HMS3656J06, HMS3712C22, Pharmakon1600-01503266, BCP07558, KS-00000XH0, Tox21_110189, Tox21_500733, 2593AH, BN0389, GP8428, METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMIDAZOL-2YL)CARBAMATE, MFCD00005588, NSC759882, s2775, STK832483, Nocodazole, >=99% (TLC), powder, AKOS000538825, AKOS015901529, Tox21_110189_1, AN-2403, CCG-101240, CCG-208075, CP-0076, CS-1893, DB08313, LP00733, LS-1178, MCULE-3133043736, NSC-759882, IDI1_002086, QTL1_000062, SMP2_000261, NCGC00015647-01, NCGC00015647-02, NCGC00015647-03, NCGC00015647-04, NCGC00015647-06, NCGC00015647-07, NCGC00015647-08, NCGC00015647-09, NCGC00015647-10, NCGC00015647-11, NCGC00015647-12, NCGC00015647-13, NCGC00015647-14, NCGC00015647-15, NCGC00015647-18, NCGC00025058-01, NCGC00025058-02, NCGC00025058-03, NCGC00025058-04, NCGC00025058-05, NCGC00025058-06, NCGC00025058-07, NCGC00025058-08, NCGC00025058-09, NCGC00025058-10, NCGC00261418-01, AC-25615, AM807900, BAS 00319017, HY-13520, NCI60_001911, SC-21129, ST078193, SBI-0050711.P002, AB0109635, EU-0100733, FT-0660415, C13719, D05197, M 1404, R17,934, SR-01000075979-1, SR-01000075979-3, SR-01000075979-6, SR-01000075979-9, BRD-K12539581-001-06-2, BRD-K12539581-001-14-6, I14-14250, methoxy-N-[6-(2-thienylcarbonyl)benzimidazol-2-yl]carboxamide, methyl 6-(thien-2-ylcarbonyl)-1H-benzimidazol-2-ylcarbamate, 2-Benzimidazolecarbamic acid, 5-(2-thenoyl)-, methyl ester (8CI), methyl [6-(thiophen-2-ylcarbonyl)-1H-benzimidazol-2-yl]carbamate, methyl N-(6-thiophen-2-ylcarbonyl-1H-benzimidazol-2-yl)carbamate, methyl N-[5-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate, N-[6-(2-thenoyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester, [[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]]carbamic acid methyl ester, [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester, carbamic acid, [6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester, Carbamic acid, N-[5-(2-thenoyl)-1H-benzimidazol-2-yl]-, methyl ester, methyl (6-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate, METHYL [5-(2-THIENYL-CARBONYL)-1H-BENZ-IMIDAZOLE-2-YL]-CARBAMATE, methyl N-[5-(thiophene-2-carbonyl)-1H-1,3-benzodiazol-2-yl]carbamate, methyl N-[5-(thiophene-2-carbonyl)-3H-1,3-benzodiazol-2-yl]carbamate, [5-(Thiophene-2-carbonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester, [6-(Thiophene-2-carbonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester, Carbamic acid, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester, N-[6-[oxo(thiophen-2-yl)methyl]-1H-benzimidazol-2-yl]carbamic acid methyl ester

ID: 1236

InChIKey: KZFDKINRISJFCO-UHFFFAOYSA-N
SMILES: CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2143
synonyms found at PubChem are:
Aminobenztropine, 3-(2'-Aminobenzhydryloxy)tropane, CHEMBL330957, 88097-86-3, ABHT, Aminobenztropine, solid, Spectrum_000273, SpecPlus_000797, Spectrum3_000745, Spectrum4_001211, Spectrum5_001758, D03WGD, AC1L1D0L, AC1Q57ZN, Lopac0_000126, BSPBio_002330, KBioGR_001642, KBioSS_000753, MLS000859976, DivK1c_006893, SPECTRUM2300334, SCHEMBL1231000, 2-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy-phenylmethyl]aniline, CTK5F9344, KBio1_001837, KBio2_000753, KBio2_003321, KBio2_005889, KBio3_001550, CHEBI:125384, HMS2232P19, HMS3260I14, HMS3374M03, Tox21_500126, BDBM50080415, 2-{[(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)oxy](phenyl)methyl}aniline, AKOS030582729, CCG-204221, LP00126, NCGC00015005-02, NCGC00015005-03, NCGC00015005-04, NCGC00015005-05, NCGC00015005-06, NCGC00093617-01, NCGC00093617-02, NCGC00093617-03, NCGC00093617-04, NCGC00260811-01, SMR000326835, A-138, EU-0100126, SR-01000075300, SR-01000075300-1, BRD-A28095882-001-05-7, 3-(2 inverted exclamation marka-Aminobenzhydryloxy)tropane, 2-[(8-Methyl-8-aza-bicyclo[3.2.1]oct-3-yloxy)-phenyl-methyl]-phenylamine, Benzenamine,2-[[(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)oxy]phenylmethyl]-

ID: 1237

InChIKey: KZJWDPNRJALLNS-VJSFXXLFSA-N
SMILES: CC[C@H](CC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 222284
synonyms found at PubChem are:
BETA-SITOSTEROL, Sitosterol, 83-46-5, Cupreol, Quebrachol, 22,23-Dihydrostigmasterol, Azuprostat, Triastonal, Cinchol, Rhamnol, Harzol, beta-Sitosterin, B-Sitosterol, alpha-Dihydrofucosterol, Nimbosterol, Stigmast-5-en-3beta-ol, Sito-Lande, (-)-beta-Sitosterol, (3beta)-Stigmast-5-en-3-ol, Angelicin (steroid), 24alpha-Ethylcholesterol, a-Dihydrofucosterol, .beta.-Sitosterin, .beta.-Sitosterol, Phytosterol, Prostasal, NSC8096, (24R)-Stigmast-5-en-3beta-ol, SITOSTEROL, BETA, .alpha.-Dihydrofucosterol, (24R)-Ethylcholest-5-en-3beta-ol, 24.alpha.-Ethylcholesterol, Stigmast-5-en-3-ol, Stigmast-5-en-3.beta.-ol, UNII-S347WMO6M4, Sobatum, CHEMBL221542, S347WMO6M4, Stigmasterol, 22,23-dihydro-, CHEBI:27693, Stigmast-5-en-3-ol, (3b)-, C29H50O, Stigmast-5-en-3-ol, (3beta)-, NSC49083, SKF 14463, Stigmasterol,23-dihydro-, Betaprost, Stigmast-5-en-3-ol, (3.beta.)-, 24beta-Ethylcholesterol, 5-Stigmasten-3beta-ol, (3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 14-((1S,4R)-4-ethyl-1,5-dimethylhexyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol, 64997-52-0, 24-alpha-Ethylcholesterol, Stigmast-5-en-3-beta-ol, delta5-Stigmasten-3-beta-ol, SR-05000002307, CCRIS 5529, (3-beta)-Stigmast-5-en-3-ol, beta Sitosterol, Sitosterol beta, a-Phytosterol, NSC 8096, b-Sitosterin, beta-Phytosterol, Beta-sistosterol, EINECS 201-480-6, alpha-Phytosterol, .beta.Sitosterin, .beta.Sitosterol, Steroids, hydroxy, CAS-83-46-5, Refined soy sterol, NCGC00095716-01, 68555-08-8, (-)-b-Sitosterol, AI3-26020, Harzol (TN), 24a-Ethylcholesterol, alpha.Dihydrofucosterol, D5-Stigmasten-3b-ol, Stigmast-5-en-3b-ol, AC1L5BKV, Prestwick0_000985, Prestwick1_000985, Prestwick2_000985, Prestwick3_000985, Delta5-Stigmasten-3b-ol, SITOSTEROL, BETA-, stigmast-5-ene-3beta-ol, DSSTox_CID_2481, bmse000477, D0Y7LD, beta-Sitosterol, >=70%, beta-Sitosterol (Synthetic), DSSTox_RID_76601, BIDD:PXR0121, DSSTox_GSID_22481, SCHEMBL16105, 22,23-dihydro-Stigmasterol, BSPBio_001049, ARONIS24293, BIDD:ER0636, SPBio_002950, BPBio1_001155, MEGxp0_001710, Soybean oil sterols phytosterols, DTXSID5022481, (24R)-Stigmast-5-en-3b-ol, ACon1_000287, CTK3E8043, BBC/449, KZJWDPNRJALLNS-VJSFXXLFSA-N, MolPort-001-742-476, HMS1571E11, HMS2098E11, (24R)-Ethylcholest-5-en-3b-ol, (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, 17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 24-Ethylcholest-5-en-3.beta.-ol, HY-N0171, NSC-8096, NSC18173, ZINC4095717, beta-Sitosterol, analytical standard, EINECS 271-413-3, Tox21_111514, ANW-41688, BDBM50218197, beta-Sitosterol, synthetic, >=95%, LMST01040129, NSC-18173, NSC-49083, s2273, SBB012603, AKOS005267194, CCG-208334, CS-6009, MCULE-2409753351, beta-Sitosterol, from soybean, >=96%, SMP1_000274, NCGC00142598-02, NCGC00142598-03, AC-24183, AN-24063, AN-38045, BC201729, M047, NCI60_041777, SC-19725, SC-57983, ST069312, AB0015024, LS-195633, TR-037936, AB00513984, N1688, S0040, C01753, D08518, I06-1624, Q-200712, SR-05000002307-2, SR-05000002307-3, 8295076E-C876-4B41-ADF5-02A644EEA34F, beta-Sitosterol, analytical standard, from soybean, >=40%, beta-Sitosterol, primary pharmaceutical reference standard, UNII-3OE0DD1I5J component KZJWDPNRJALLNS-VJSFXXLFSA-N, UNII-B46B6DD20U component KZJWDPNRJALLNS-VJSFXXLFSA-N, UNII-D083681CDS component KZJWDPNRJALLNS-VJSFXXLFSA-N, Beta-sitosterol, European Pharmacopoeia (EP) Reference Standard, beta-Sitosterol, United States Pharmacopeia (USP) Reference Standard, beta-Sitosterol, certified reference material, 100 mug/mL in chloroform, (3S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, 15764-35-9, 182512-23-8, 76772-70-8

ID: 1238

InChIKey: LAAWXMXXTTUZLY-QDILMJESSA-N
SMILES: C(C[C@@H](C(=O)O)N)CN.C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 71306754
synonyms found at PubChem are:
UNII-7PU8A2CY6Q, 7PU8A2CY6Q, Diornithine oxoglurate dihydrate, Ornithine oxoglutarate monohydrate, L-Ornithine oxoglutarate monohydrate, 2C5H12N2O2.C5H6O5.2H2O, 185423-57-8, L-Ornithine alpha-ketoglutarate(2:1) dihydrate, L-Ornithine alpha-ketoglutarate (2:1) dihydrate, 144O423, (S)-2,5-diaminopentanoic acid compound with 2-oxopentanedioic acid (2:1) dihydrate

ID: 1239

InChIKey: LAJXCUNOQSHRJO-ZYGJITOWSA-N
SMILES: C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5458385
synonyms found at PubChem are:
cytochalasin e, 36011-19-5, CHEBI:68201, CYTOCHALASINE, NSC175151, Cytochalasin E from Aspergillus clavatus, HSDB 3548, EINECS 252-835-7, NSC 175151, 21,23-Dioxa(13)cytochalasa-13,19-diene-1,17,22-trione, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-, 6,7-Epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-(13)cytochalas-13,19-diene-17,22-dione, SCHEMBL33617, CHEMBL494856, CCG-39859, MFCD00005178, ZINC42805205, MCULE-4194934591, NSC-175151, NCGC00380287-01, C-22913, 21,19-diene-1,17,22-trione, 6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-

ID: 1240

InChIKey: LAMKJRBNAYFPIQ-UHFFFAOYSA-N
SMILES: CN(C1=CC(=O)C(=O)C=C1)NO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5353329
synonyms found at PubChem are:
3,4-dephostatin, Me-3,4-dephostatin, 3,4-Dihydroxy-N-methyl-N-nitrosoaniline, Methyl-3,4-dephostatin, Lopac-M-9440, L2037 (beta-lapachone), P00017, Lopac0_000871, AC1NS425, SCHEMBL3894012, CHEMBL1256623, SCHEMBL13448407, BDBM81347, CTK8F4799, EU0100871_PURCHASED, HMS3262P03, ZINC3870870, Tox21_500871, HSCI1_000165, 3,4-Dihydroxy-N-methyl-N-nitrosaline, AKOS006275313, CCG-204953, LP00871, NCGC00015706-01, NCGC00015706-02, NCGC00015706-03, NCGC00015706-04, NCGC00094195-01, NCGC00094195-02, NCGC00261556-01, EU-0100871, M9440, M 9440, Methyl-3,4-dephostatin, >98% (HPLC), powder, N-(3,4-dihydroxyphenyl)-N-methyl-nitrous amide, SR-01000076015, SR-01000076015-1, 4-[(hydroxyamino)-methylamino]cyclohexa-3,5-diene-1,2-dione, 173043-84-0

ID: 1241

InChIKey: LAROMNHHFPRNET-UHFFFAOYSA-N
SMILES: C1CC2=CC=CC=C2C3=NN=C(C=C3C1)NCCN4CCOCC4.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 195164
synonyms found at PubChem are:
SR-95639A, 115767-94-7, Morpholineoethylamino-3-benzocyclohepta(5,6-c)pyridazine, Prestwick_765, AC1L4ZJR, AC1Q3APS, SCHEMBL10389077, DTXSID40151186, LAROMNHHFPRNET-UHFFFAOYSA-N, HMS1569A14, CCG-220406, n-[2-(morpholin-4-yl)ethyl]-6,7-dihydro-5h-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-amine dihydrochloride, SR-01000841214, SR-01000841214-2, 5H-Benzo(6,7)cyclohepta(1,2-c)pyridazin-3-amine, 6,7-dihydro-N-(2-(4-morpholinyl)ethyl)-, dihydrochloride

ID: 1242

InChIKey: LAVOESILOACOFW-PEZBUJJGSA-N
SMILES: CC1(CC2C1CCC(=C)/C(=N\O)/CCC2=C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6287034
synonyms found at PubChem are:
5-HYDROXYIMINOISOCARYOPHYLLENE, Spectrum5_001777, BSPBio_002771, SPECTRUM300049, AC1O3O32, CHEMBL1418023, SCHEMBL12998378, CCG-38596, SDCCGMLS-0066508.P001, NCGC00095574-01, NCGC00095574-02, (NZ)-N-(11,11-dimethyl-4,8-dimethylidene-5-bicyclo[7.2.0]undecanylidene)hydroxylamine

ID: 1243

InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N
SMILES: C1CSC2=NC(CN21)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68628
synonyms found at PubChem are:
Tetramisole hydrochloride, 5086-74-8, Anthelvet, Citarin, Concurat, Tetramisole HCl, Ascarotrat, Nilverom, Ripercol, Nilverm, Pig Wormer, Orovermol, Solaskil hydrochloride, Citarin (VAN), Tetramisole (hydrochloride), McN-JR-8299-11, McN JR 8299, Bayer 9051, Spartakon, NSC 170985, McN-JR-8299, Tetramisole hydrochloride [USAN], EINECS 225-799-5, R 8299, DL-Tetramisole hydrochloride, Nemicide, CHEBI:9496, 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride, DL-6-Phenyl-2,3,5,6-tetrahydroimidazole(2,1-b)thiazole-hydrochloride, (+-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride, L(-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole, Tetramisole hydrochloride (USAN), 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (+-)-, 4641-34-3, SR-01000076148, mcn-jr 8299, Verminject, Curaminth, Ripereol, (6S)-6-phenyl-2H,3H-2-imidazolino[2,1-b]1,3-thiazolidine, chloride, 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride, NCGC00094446-03, Prestwick_854, C11H12N2S, Ergamisol hydrochloride, Tetramisol hydrochloride, (.+-.)-Anthelvet, AC1Q1HFD, dl tetramisole hydrochloride, AC1L2A4J, McNJR8299, SCHEMBL44230, BMK1-H7, Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, MLS000028416, CHEMBL554891, (+-)-Tetramisole hydrochloride, CTK8G3409, (+/-)-Tetramisole Hydrochloride, LAZPBGZRMVRFKY-UHFFFAOYSA-N, MolPort-003-933-970, (.+-.)-Tetramisole hydrochloride, HMS1569N11, Pharmakon1600-01503245, Pharmakon1600-01505679, HY-B1194, KS-00000QX9, TETRAMISOLE HYDROCHLORIDE, BP, Tox21_501194, NSC170985, NSC215179, NSC758437, NSC759175, s4094, SBB056947, tetramisole hydrochloride hydrochloride, AKOS015900432, CCG-213508, CCG-220545, CCG-222498, CS-4801, HS-0026, LP01194, NSC 215179, NSC-170985, NSC-215179, NSC-758437, NSC-759175, NCGC00094446-01, NCGC00094446-02, NCGC00094446-04, NCGC00094446-05, NCGC00261879-01, AC-22590, EN002719, I016, LS-80640, RP 16535, SMR000058395, KB-293877, TR-030849, EU-0101194, FT-0659999, ST50989904, WLN: T55 AN DN FS DUTJ CR &GH -R, C11337, D06091, R-8299, T 1512, Tetramisole hydrochloride, phosphatase inhibitor, 5086-74-8, 5036-02-2(free base), I14-0950, SR-01000076148-1, SR-01000076148-5, W-105926, (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2, 1-b]thiazole, 2,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride, DL -2,3,5,6-Tetrahydro-6-phenylimidazo- [2,1-b]-thiazole, Tetramisole hydrochloride, VETRANAL(TM), analytical standard, 2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole Hydrochloride, DL-6-Phenyl-2,5,6-tetrahydroimidazole[2,1-b]thiazole-hydrochloride, (+/-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Hydrochloride, (.+-.)-2,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride, DL-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-b]-thiazole hydrochloride, Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (.+-.)-, ( inverted exclamation markA)-Tetramisole hydrochloride;DL-Tetramisole hydrochloride;R-8299, ( inverted question mark)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride, ( inverted exclamation markA)-2,3,5,6-EACa-6-+/-(1/2)>>ussasso(2) cent[2,1-b]acsso NIEaNI, AKOS025116928, MCULE-8104126881, AKOS025116953, AKOS015918350, A828325, I14-8097, hydron; 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole; chloride, hydron; 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; chloride

ID: 1244

InChIKey: LBARATORRVNNQM-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 54765
synonyms found at PubChem are:
BAMBUTEROL HYDROCHLORIDE, 81732-46-9, Bambuterol HCl, Bambuterol (hydrochloride), CHEBI:59167, Bambec (TN), Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester, DSSTox_CID_25515, DSSTox_RID_80925, DSSTox_GSID_45515, Prestwick_777, Bambuterolhydrochloride, SR-05000001470, [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate;hydrochloride, NCGC00016947-01, AC1L1HP3, CAS-81732-46-9, C18H30ClN3O5, MLS002153784, SCHEMBL744580, SPECTRUM1505173, CHEMBL1603534, DTXSID8045515, CTK8F7907, AOB5925, MolPort-003-666-597, HMS1569I03, Pharmakon1600-01505173, BCP09503, KS-000017WS, KWD 2183, Tox21_110702, HY-17501A, MFCD03427293, NSC758916, s4277, AKOS015951295, Tox21_110702_1, API0001588, CCG-213966, CS-4335, KS-1333, MCULE-6324373983, NSC-758916, TRA0061229, VA10370, NCGC00096057-01, NCGC00179546-05, AC-15641, AN-36290, CC-24244, SMR001233167, AB1009367, AX8016968, B4564, FT-0625127, ST24046005, D07489, Bambuterol hydrochloride, >98% (HPLC), powder, 732B469, C-21781, SR-05000001470-4, SR-05000001470-5, Bambuterol hydrochloride, European Pharmacopoeia (EP) Reference Standard, 5-(2-(t-butylamino)-1-hydroxyethyl)-1,3-phenylene bis(dimethylcarbamate) hydrochloride, 5-(2-(tert-butylamino)-1-hydroxyethyl)-1,3-phenylene bis(dimethylcarbamate) hydrochloride, 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride, [3-[2-(tert-butylamino)-1-hydroxy-ethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate hydrochloride, [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate hydrochloride, Carbamic acid, dimethyl-, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-1,3-phenylene ester, monohydrochloride, Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1), Dimethylcarbamic Acid 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene Ester Monohydrochloride, N,N-Dimethylcarbamic Acid 3-[[(Dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl Ester Hydrochloride, AKOS026750107

ID: 1245

InChIKey: LBSFSRMTJJPTCW-DSXUQNDKSA-N
SMILES: COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 91558
synonyms found at PubChem are:
Quinine HCl, Quinine hydrochloride, Quinine chloride, 130-89-2, UNII-7CS0WNO31M, Chinimetten, FEMA No. 2976, CCRIS 2002, EINECS 205-001-1, Quinine muriate, 7CS0WNO31M, AI3-62121, QUININE, MONOHYDROCHLORIDE, (8alpha,9R)-6'-Methoxycinchonan-9-ol monohydrochloride, 6'-Methoxycinchonan-9-ol monohydrochloride, (8alpha,9R)-, Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8alpha,9R)-, Quinine hydrochloride dihydrate, Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, dihydrate, (8alpha,9R)-, Chinine hydrochloride, Quinine, hydrochloride, 7549-43-1, EINECS 231-437-7, AC1L3MBD, SCHEMBL184367, Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8alpha,9R)-, CHEMBL588046, DTXSID7044213, LBSFSRMTJJPTCW-DSXUQNDKSA-N, MolPort-000-146-143, TCMDC-123484, TCMDC-125479, Cinchonan-9-ol, 6'-methoxy-, hydrochloride, (8alpha,9R)-, AKOS016002029, 6'-methoxycinchonan-9-ol hydrochloride, API0024401, LS-2374, AN-20142, SC-18977, ST24031590, Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:?), (8alpha,9R)-, Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8-alpha,9R)-, Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8-alpha,9R)- (9CI), (R)-(6-methoxy-4-quinolyl)-[(2S,4S,5R)-5-vinylquinuclidin-2-yl]methanol hydrochloride, (R)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride, (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol hydrochloride, 11034-23-4, 70181-37-2, 918656-55-0

ID: 1246

InChIKey: LBVZWEWTNUDWNS-YRNVUSSQSA-N
SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)/C=C/C(=O)NCC3=CC=C(C=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6160690
synonyms found at PubChem are:
GR 46611, GR46611, GR 4661, 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide, CHEMBL344127, 185259-85-2, SR-01000076206, 3-(3-(2-Dimethylaminoethyl)-1H-indol-5-yl)-N-(4-methoxybenzyl)acrylamide, AC1O1Z0D, Lopac0_000069, MLS001056583, SCHEMBL4784832, CHEBI:93195, (E)-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-(4-methoxybenzyl)acrylamide, LBVZWEWTNUDWNS-YRNVUSSQSA-N, MolPort-003-941-553, HMS2233M08, HMS3260M19, ZINC840177, Tox21_500069, BDBM50054764, PDSP1_001395, PDSP2_001379, AKOS024458670, API0008779, CCG-204164, GR-4661, LP00069, 3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-((4-methoxyphenyl)methyl)-2-propenamide, NCGC00024831-02, NCGC00024831-03, NCGC00024831-04, NCGC00024831-05, NCGC00260754-01, CC-13839, SMR000326973, RT-013116, EU-0100069, G 8543, C-35719, SR-01000076206-1, SR-01000076206-3, BRD-K68190965-001-01-4, 3-[3-(2-dimethylaminoethyl)-1h-indol-5-yl]-n-(4-methoxybenzyl) acrylamide, 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)-acrylamide, (E)-3-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-(4-methoxy-benzyl)-acrylamide, (E)-3-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide, 2-Propenamide, 3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-((4-methoxyphenyl)methyl)-

ID: 1247

InChIKey: LCEURBZEQJZUPV-UHFFFAOYSA-N
SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=CC=C2OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 134453
synonyms found at PubChem are:
NISOXETINE HYDROCHLORIDE, 57754-86-6, Lilly 94939, Nisoxetine Inhibitor, Nisoxetine HCl, 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine hydrochloride, Benzenepropanamine, gamma-(2-methoxyphenoxy)-N-methyl-, hydrochloride, (+-)-, SMR000326908, SR-01000075280, NSC 298819, AC1Q3DNE, AC1L34MR, MLS000860050, MLS002222190, SCHEMBL467262, CHEMBL1256695, Nisoxetine hydrochloride_x000D_, DTXSID00110037, MolPort-003-666-822, HMS1570F22, BCP28059, Tox21_500901, BN0383, NSC298819, 3-(2-methoxyphenoxy)-n-methyl-3-phenylpropan-1-amine hydrochloride(1:1), AKOS015896614, API0008870, CCG-220910, CCG-222205, LP00901, NSC-298819, NCGC00094216-01, NCGC00094216-02, NCGC00261586-01, LS-31022, LY-94,939, EU-0100901, FT-0630345, N-151, Nisoxetine hydrochloride, solid, >=98% (HPLC), I06-2301, SR-01000075280-1, SR-01000075280-3, SR-01000075280-6, (+/-)-?-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride, ( inverted exclamation markA)-|A-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride, 57226-34-3, SCHEMBL14973458

ID: 1248

InChIKey: LCHACRBDLUKTTM-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)F)OCCCC3=CN=CN3)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957588
synonyms found at PubChem are:
3-(1H-Imidazol-4-yl)propyl di(p-fluorophenyl)methyl ether hydrochloride, 4-{3-[Bis-(4-fluoro-phenyl)-methoxy]-propyl}-1H-imidazole HCl, 5-{3-[Bis-(4-fluoro-phenyl)-methoxy]-propyl}-3H-imidazol-1-ium chloride;3-(1H-Imidazol-4-yl)propyl-di(4-fluoro-phenyl)-methyl ether HCl, EU-0100695, CHEMBL1256687, CTK8F4564, Tox21_500695, CCG-221999, LP00695, NCGC00094049-01, NCGC00261380-01, I-160, SR-01000075944, SR-01000075944-1, 3-(1H-Imidazol-4-yl)propyl di(p-fluorophenyl)methyl ether hydrochloride, powder, 4-{3-[Bis-(4-fluoro-phenyl)-methoxy]-propyl}-1H-imidazole inverted exclamation mark currency HCl, 403601-83-2

ID: 1249

InChIKey: LCNBIHVSOPXFMR-UHFFFAOYSA-N
SMILES: C(CCNCCCN)CN.Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9539
synonyms found at PubChem are:
Spermidine trihydrochloride, 334-50-9, N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride, N1-(3-Aminopropyl)butane-1,4-diamine trihydrochloride, Spermidine hydrochloride, UNII-1O14BED398, EINECS 206-379-0, 1,4-BUTANEDIAMINE, N-(3-AMINOPROPYL)-, TRIHYDROCHLORIDE, NSC 528399, Spermidine, Trihydrochloride, 1O14BED398, 1,4-Butanediamine, N-(3-aminopropyl), hydrochloride, n-(3-aminopropyl)butane-1,4-diamine trihydrochloride, 4-Azoniaoctamethylenediammonium trichloride, S-7320, N-(3-aminopropyl)-1,4-butanediamine, trihydrochloride, 1,4-Butanediamine, N1-(3-aminopropyl)-, hydrochloride (1:3), Spermidine HCl, SR-01000075461, AC1Q3ACE, AC1L1T9P, C7H19N3.3HCl, SPECTRUM1503940, CHEMBL1473196, DTXSID0059825, CTK8G3180, MolPort-003-981-164, Tox21_501047, 7714AH, ACM334509, BN0498, CCG-39054, MFCD00012918, AKOS016013158, LP01047, NCGC00094332-01, NCGC00094332-02, NCGC00261732-01, AK126526, LS-45645, AX8151797, DB-048408, Spermidine trihydrochloride, >=98% (TLC), B6523, EU-0101047, FT-0631974, ST24031458, Spermidine trihydrochloride, >=99.0% (AT), S 2501, SR-01000075461-2, SR-01000075461-3, SR-01000075461-6, N'-(3-aminopropyl)butane-1,4-diamine trihydrochloride, N'-(3-aminopropyl)butane-1,4-diamine;trihydrochloride, Spermidine trihydrochloride, BioXtra, >=99.5% (AT), N\'-(3-aminopropyl)butane-1,4-diamine,trihydrochloride, N1-(3-Aminopropyl);butane-1,4-diamine trihydrochloride, 35408-56-1

ID: 1250

InChIKey: LCOLXNYRAYSOSS-UHFFFAOYSA-N
SMILES: CC1C2=CC(=C(C=C2CCN1S(=O)(=O)C3=CN(C(=N3)C)C)OC)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"N Liu" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile" "J Liao" "C Pavel" "SM Anjos"

CID is 2812733
synonyms found at PubChem are:
AC1MDKSJ, Oprea1_613690, MLS000850277, AC1Q470D, CHEMBL1715865, MolPort-001-807-960, HMS2781E12, CCG-51849, MCULE-4302786397, 2-(1,2-dimethylimidazol-4-yl)sulfonyl-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline, SMR000456295, SR-01000641125-1, 2-(1,2-dimethyl-1H-imidazole-4-sulfonyl)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline, 2-[(1,2-dimethyl-1H-imidazol-4-yl)sulfonyl]-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

ID: 1251

InChIKey: LCUMYVYIHXYBIA-FOWTUZBSSA-N
SMILES: CC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5487525
synonyms found at PubChem are:
Tyrphostin AG 879, AG 879, 148741-30-4, AG-879, alpha-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide, MFCD00236450, C18H24N2OS, (E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide, Tyrphostin Ag-879, AC1NUPK6, Lopac-T-2067, BMK1-D4, SCHEMBL607701, SCHEMBL607702, TYRPHOSTIN AG 879, CHEMBL539947, SCHEMBL3731617, CHEBI:93041, MolPort-003-959-688, MolPort-035-944-092, MolPort-046-033-686, HMS1361F20, HMS1791F20, HMS3263L11, HMS3402F20, CS-D0050, Tyrphostin AG 879 (AG 879), Tox21_501175, 2775AH, EI-258, s2816, AKOS024256594, ZINC100435325, CCG-100632, Tyrphostin AG 879, 99% (HPLC), NCGC00016007-01, NCGC00016007-02, NCGC00016007-03, NCGC00016007-04, NCGC00016007-05, NCGC00016007-06, NCGC00016007-07, NCGC00094432-01, NCGC00094432-02, NCGC00094432-03, NCGC00094432-04, NCGC00094432-05, NCGC00261860-01, HY-20878, KB-125274, B1544, EU-0101175, T 2067, 3,5-Di-t-butyl-4-hydroxybenzylidine cyanothioacetamide, 2-CYANO-3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROP-2-ENETHIOAMIDE, (2E)-3-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2-propenethioamide, 2-Propenethioamide, 3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-2-cyano-, (E)-, AG-879|||(E)-3-Amino-2-[(3,5-ditert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3-sulfanylprop-2-enenitrile

ID: 1252

InChIKey: LDCYZAJDBXYCGN-VIFPVBQESA-N
SMILES: C1=CC2=C(C=C1O)C(=CN2)C[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 439280
synonyms found at PubChem are:
5-hydroxy-L-tryptophan, L-5-Hydroxytryptophan, oxitriptan, 4350-09-8, 5-hydroxytryptophan, Cincofarm, Levothym, Pretonine, Tript-OH, (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid, L-5-Htp, Quietim, 5-Hydroxytryptophan L-form, Oxyfan, Levotinine, Serotonyl, Telesol, 5-hydroxy-L-tryptophane, hydroxytryptophan, (S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid, Tryptophan, 5-hydroxy-, L-Tryptophan, 5-hydroxy-, Oxitriptan [INN], 5-HTP, 5-Hydroxyl-L-tryptophan, Oxitriptanum [INN-Latin], Oxitriptano [INN-Spanish], UNII-C1LJO185Q9, Tryptophan, 5-hydroxy-, L-, C1LJO185Q9, CCRIS 4418, CHEBI:17780, LDCYZAJDBXYCGN-VIFPVBQESA-N, Oxitriptan (INN), EINECS 224-411-1, BRN 0088200, NCGC00091062-04, C11H12N2O3, DSSTox_CID_5437, L-2-Amino-3-(5-hydroxyindolyl)propionic acid, DSSTox_RID_77786, DSSTox_GSID_25437, Q-200544, (2S)-2-amino-3-(5-hydroxyindol-3-yl)propanoic acid, 34953-84-9, CAS-4350-09-8, 5-Hydroxytryptophan L form, 5-22-14-00278 (Beilstein Handbook Reference), Oxitriptano, Oxitriptanum, Serotain, Tripten, Levothym (TN), 5 Hydroxytryptophan, 5-Hydroxytryptophane, 5-hydroxy tryptophan, Tryptophan, 5-HTP, PubChem19056, PubChem20675, 5HTP, 145224-90-4, (S)-5-Hydroxytryptophan, Lopac-H-9772, bmse000457, D09BNS, H-Trp(5-OH)-OH, 5-HYDROXY-TRYPTOPHAN, Lopac0_000627, SCHEMBL43243, MLS002153452, 5-hydroxytryptophan - 5-HTP, 5HW;, AC1L971E, CHEMBL350221, GTPL4671, 5-Hydroxy-L-tryptophan, powder, Jsp001064, DTXSID1025437, CTK1H0273, AOB5288, MolPort-002-507-275, HMS2231H15, HMS3261N16, ZINC895330, Tox21_111073, Tox21_201032, Tox21_500627, ANW-13886, BDBM50403163, CH-045, CH0064, GM9337, MFCD00064341, Oxitriptan (5-Hydroxy-L-tryptophan), RW1864, AKOS004119863, Tox21_111073_1, CCG-204715, CS-W019879, DB02959, EBD2204426, LP00627, MCULE-7974218863, Ro 3-5940, RTR-016857, NCGC00015526-01, NCGC00091062-01, NCGC00091062-02, NCGC00091062-03, NCGC00091062-05, NCGC00091062-06, NCGC00091062-07, NCGC00091062-08, NCGC00091062-09, NCGC00258585-01, NCGC00261312-01, AC-24420, ACM314062447, AJ-24178, AK-40553, AK-51351, AS-12269, BR-40553, CC-21832, CC-29801, KB-43419, SC-15640, SC-19052, SC-19914, SMR001230815, ST048776, AB1009506, AX8033170, KB-246216, ST2412038, AM20060629, EU-0100627, FT-0627633, 50H098, C00643, D07339, H 9772, S-1370, A826297, C-12162, SR-01000075584, DL-2-Amino-3-[3-(5-hydroxyindole)]propionic acid, I10-0656, SR-01000075584-1, 2-Amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid, S(+)-1-alpha-Amino-5-hydroxyindole-3-propionic acid, 5-Hydroxy-L-tryptophan, 98% (calc. on dried substance), CDAD59D9-D915-46DD-8029-48C808976B7C, UNII-9181P3OI6N component LDCYZAJDBXYCGN-VIFPVBQESA-N, (2S)-2-azanyl-3-(5-oxidanyl-1H-indol-3-yl)propanoic acid, 5-Hydroxy-L-tryptophan, United States Pharmacopeia (USP) Reference Standard, L-5-HYDROXYTRYPTOPHAN (SEE ALSO 5-HYDROXYTRIPTOPHAN 56-69-9), (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic Acid (5-Hydroxytryptophan), 1228817-95-5, 4PQ, (2S)-2-ammonio-3-(5-hydroxy-1H-indol-3-yl)propanoate, (2S)-2-azaniumyl-3-(5-hydroxy-1H-indol-3-yl)propanoate, AC1ODZ3N, CHEBI:58266, 5-hydroxy-L-tryptophan zwitterion, ZB015023

ID: 1253

InChIKey: LDDHMLJTFXJGPI-UHFFFAOYSA-N
SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 181458
synonyms found at PubChem are:
MEMANTINE HYDROCHLORIDE, 41100-52-1, Memantine HCL, 3,5-dimethyladamantan-1-amine hydrochloride, 3,5-Dimethyl-1-adamantanamine hydrochloride, Namenda, Akatinol, Axura, Namenda XR, memantine.HCl, Memantine (hydrochloride), UNII-JY0WD0UA60, 1-Amino-3,5-dimethyladamantane Hydrochloride, JY0WD0UA60, CHEBI:64323, D-145, 3,5-dimethyladamantan-1-aminium chloride, MLS001332605, 3,5-Dimethyl-1-aminoadamantane hydrochloride, 3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride, D 145, (3,5-Dimethyl-1-adamantyl)amine hydrochloride, Mantine, Ebixza, 3,5-dimethyltricyclo[3.3.1.13,7]decan-1-amine hydrochloride, 3,5-dimethyladamantanylamine, chloride, SMR000875213, 3,5-dimethyladamantan-1-amine;hydrochloride, SR-01000075458, 3,5-Dimethyltricyclo(3.3.1.13,7)decan-1-amine hydrochloride, Memary, Memantine hydrochloride [USAN], SUN Y7017, 1,3-Dimethylaminoadamantane hydrochloride, 3,5-DIMETHYLADAMANTAN-1-AMINE HCL, EINECS 255-219-6, Namenda (TN), Memary (TN), Memantin hydrochloride, NSC 102290, ACMC-209jif, SCHEMBL3053, CHEMBL1699, KSC911M5N, MLS001332606, SPECTRUM1501121, AC1L492E, CTK8B1656, HY-B0365A, SUN-Y7017, AOB5318, Memantine hydrochloride (Namenda), N06DX01, NMI-131, LDDHMLJTFXJGPI-UHFFFAOYSA-N, MolPort-003-666-358, HMS1571C17, HMS1921H03, Pharmakon1600-01501121, 19982-08-2 (Parent), KS-00000X1M, 3,5-Dimethylamantadine hydrochloride, Memantine hydrochloride (JAN/USAN), Tox21_500861, 3,5-Dimethyl-1-aminoadamantane HCl, AC-559, ANW-29557, BG0374, CCG-39018, MFCD00214336, MRZ-2/145, NSC102290, NSC757843, s2043, SBB003390, AKOS015889460, BCP9000253, CS-2422, LP00861, MCULE-6635165082, NC00680, NSC-102290, NSC-757843, RTR-016345, NCGC00094186-01, NCGC00094186-02, NCGC00094186-03, NCGC00261546-01, AN-15700, AS-13331, BC208848, BR-44671, CPD000058926, CPD000875213, H908, SAM001246743, SAM002699890, ST088119, 3,5-Dimethyl-1-adamantanamineHydrochloride, AB0013351, AB2000447, AX8033628, TR-016345, 4CH-006120, AM20070534, D3608, EU-0100861, FT-0650723, 1-amino-3,5-dimethyl-adamantane hydrochloride, 3,5-dimethyladamantan-1-amine hy-drochloride, D04905, J10287, M 9292, M-2015, I01-2072, SR-01000075458-1, SR-01000075458-3, SR-01000075458-8, Z1551429722, 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride, Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-, hydrochloride, 3,5-Dimethyltricyclo(3.3.1.1(sup 3,7))decan-1-amine hydrochloride, Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-, hydrochloride, Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, 3,5-dimethyl-, hydrochloride, Memantine Hydrochlroide, AKOS026750106

ID: 1254

InChIKey: LEQAKWQJCITZNK-AXHKHJLKSA-N
SMILES: CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9915886
synonyms found at PubChem are:
Thiocolchicoside, 602-41-5, Coltramyl, Muscoril, UNII-T1X8S697GT, Thiocolchicine 2-glucoside analog, NSC 147755, Musco-ril, T1X8S697GT, 10-Thiocolchicoside, Tiocolchicoside [DCIT], Colchicoside, 10-thio-, Thiocolchicoside [INN:DCF], Q-201823, Thiocolchicosidum [INN-Latin], Tiocolchicosido [INN-Spanish], C27H33NO10S, Tiocolchicoside, Tiocolchicosido, Miorel, EINECS 210-017-7, Thiocolchicosidum, BRN 0072205, R. 271, 2-10-Di(demethoxy)-2-glucosyloxy-10-methylthiocolchicine, Coltrax, Miotens, thiocholshikoside, NSC147755, Coltramyl (TN), NCGC00016519-01, Acetamide, N-(3-(beta-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo(a)heptalen-7-yl)-, (S)-, CAS-602-41-5, N-[(7S)-1,2-dimethoxy-10-methylsulfanyl-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, 10-thio-Colchicoside, Thiocolchicoside (INN), DSSTox_CID_25330, DSSTox_RID_80807, DSSTox_GSID_45330, SCHEMBL240410, CHEMBL213907, DTXSID5045330, CHEBI:94557, Colchicoside, 10-thio- (8CI), MolPort-006-112-032, BDBM233193, HMS3713L19, KS-000016AC, Thiocolchicoside, >=98% (HPLC), ZINC4245665, Tox21_110470, AKOS016010119, 2-Demethoxy-2-glucosidoxythiocolchicine, API0009946, BRN0072205, CCG-220539, DB11582, AS-14082, SC-82836, AX8153899, FT-0675162, W0078, (s)-(methylthio)-9-oxobenzo(a)heptalen-7-yl), D07276, J90050, 602T415, BRD-K26619122-001-01-3, Thiocolchicoside crystallised from ethanol, EuropePharmacopoeia (EP) Reference Standard, Thiocolchicoside for system suitability, EuropePharmacopoeia (EP) Reference Standard, (S)-N-[3-(|A-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide, N-[(7S)-1,2-dimethoxy-10-(methylthio)-9-oxo-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, N-[(7S)-3-(|A-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide

ID: 1255

InChIKey: LFJNJRGWCDXJOG-UHFFFAOYSA-M
SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)[O-])O)O.[K+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16667740
synonyms found at PubChem are:
GINKGETIN, K salt, SPECTRUM200436, CHEMBL1314376, CCG-38358, NCGC00095478-01

ID: 1256

InChIKey: LFPGJDSJDXWCIJ-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCC1=CC=CO1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6857795
synonyms found at PubChem are:
Furan, 2-tridecyl-, 2-tridecylfuran, AVOCADANOFURAN, 25346-22-9, SDCCGMLS-0066915.P001, AC1OAH7N, SPECTRUM1505806, SCHEMBL8760627, CTK0I6826, DTXSID90425900, LFPGJDSJDXWCIJ-UHFFFAOYSA-N, NCGC00095827-01, SR-05000002497, SR-05000002497-1

ID: 1257

InChIKey: LFSCNWNADRUBLS-IWIPYMOSSA-N
SMILES: CC(=CCCC1(C=CC2=C(O1)C(=C3C(=C2OC)C(=O)C4=CC5CC6C4(O3)C(C5=O)(OC6(C)C)C/C=C(/C)\C(=O)OC)CC=C(C)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6857785
synonyms found at PubChem are:
DIMETHYL GAMBOGATE, CHEMBL1436860, Spectrum5_000523, SPECTRUM10100009, BDBM50442894, CCG-214187, SDCCGMLS-0066847.P001, NCGC00095725-01

ID: 1258

InChIKey: LFUJIPVWTMGYDG-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CNC2=O)C(=C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1340
synonyms found at PubChem are:
1,5-isoquinolinediol, 5154-02-9, 1,5-Dihydroxyisoquinoline, isoquinoline-1,5-diol, 5-Hydroxyisocarbostyril, 5-Hydroxy-1(2H)-isoquinolinone, 5-HYDROXYISOQUINOLINE-1(2H)-ONE, PARP Inhibitor IV, IQD, 5-HYDROXYISOQUINOLIN-1(2H)-ONE, CHEMBL338314, 5-Hydroxy-1(2H)-isoquinoline, CHEBI:64044, IN1292, 4pnt, NSC65585, PubChem23962, 5-Hydroxy-isoquinolinone, Lopac-I-138, AC1Q6DVI, AC1L1B9E, Lopac0_000655, SCHEMBL51697, MLS000860043, 5-hydroxy-2H-isoquinolin-1-one, BDBM27501, CTK4J4432, 5-Hydroxyisoquinolin-1(4h)-One, DTXSID60199505, LFUJIPVWTMGYDG-UHFFFAOYSA-N, MolPort-003-941-774, MolPort-022-369-359, HMS2236H08, HMS3262C11, HMS3373F20, 1(2H)-Isoquinolinone,5-hydroxy-, ZINC8616043, 1(2H)-Isoquinolinone, 5-hydroxy-, 1,5-dihydroxy-1(2H)-isoquinoline, Tox21_500655, MFCD00006900, NSC 65585, NSC-65585, AKOS005207308, AKOS022636198, CCG-204741, CD-1366, LP00655, MCULE-5823570385, SMP2_000192, NCGC00015537-01, NCGC00015537-02, NCGC00015537-03, NCGC00015537-04, NCGC00094018-01, NCGC00094018-02, NCGC00261340-01, AC-10035, AJ-57761, BC200203, KB-10678, SMR000326901, DB-051983, EU-0100655, FT-0635564, I-138, ST24044788, ST50405514, A22232, L-4573, 1,5-Isoquinolinediol, >=98% (HPLC), powder, 154I029, SR-01000075624, I14-6773, SR-01000075624-1, BRD-K90230846-001-01-5, BRD-K90230846-001-04-9, F2135-0800, Z1255402655, IQD

ID: 1259

InChIKey: LFULEKSKNZEWOE-UHFFFAOYSA-N
SMILES: CCC(=O)NC1=CC(=C(C=C1)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4933
synonyms found at PubChem are:
propanil, 709-98-8, Propanide, N-(3,4-Dichlorophenyl)propanamide, Grascide, Propanex, Propanid, Supernox, Surcopur, Dipram, Rogue, Montrose propanil, Chem Rice, Synpran N, Cekupropanil, Riselect, Stampede, Erbanil, Herbax, Strel, Dichloropropionanilide, STAM, N-(3,4-Dichlorophenyl)Propionamide, Prop job, Stam m-4, Stam LV 10, Stam F 34, Wham EZ, Stampede 360, 3,4-Dichloropropionanilide, Propanilo, Rosanil, Erban, Farmco propanil, Propanamide, N-(3,4-dichlorophenyl)-, Stam supernox, Stam 80EDF, Herbax technical, Chem-Rice, 3',4'-Dichloropropionanilide, Drexel Prop-Job, Prop-Job, Stampede 3E, Herbax 3E, Herbax 4E, Vertac Propanil 3, Vertac Propanil 4, Crystal propanil-4, Propionic acid 3,4-dichloroanilide, Herbax LV-30, Caswell No. 325, BAY 30130, FW 734, Propanil [BSI:ISO], Surpur, Propionanilide, 3',4'-dichloro-, Bayer 30 130, NSC 31312, CCRIS 3009, S 10165, UNII-F57I4G0520, HSDB 1226, 3',4'-Dichlorophenylpropionanilide, Propionic acid-3,4-dichloroanilide, EINECS 211-914-6, EPA Pesticide Chemical Code 028201, BRN 2365645, AI3-31382, CHEBI:34936, 3,4-Dichloranilid kyseliny propionove [Czech], LFULEKSKNZEWOE-UHFFFAOYSA-N, S10165, B-30,130, F57I4G0520, DSSTox_CID_2111, DSSTox_RID_76491, DSSTox_GSID_22111, CAS-709-98-8, Propanile, 110343-36-7, 3,4-Dichloranilid kyseliny propionove, Propanil (DCPA ), Spectrum_001807, SpecPlus_000398, Spectrum2_001878, Spectrum3_000819, Spectrum4_000659, Spectrum5_001948, CBMicro_000482, WLN: GR BG DMV2, AC1L1J9E, Cambridge id 5840989, Propionanilide,4'-dichloro-, SCHEMBL26871, 3',4'-Dichloropropioanilide, BSPBio_002317, KBioGR_001037, KBioSS_002300, SPECTRUM330027, MLS002207241, BIDD:ER0610, DivK1c_006494, SPBio_001756, Propanamide,4-dichlorophenyl)-, CHEMBL1222498, DTXSID8022111, CTK8E4284, KBio1_001438, KBio2_002298, KBio2_004866, KBio2_007434, KBio3_001817, LFULEKSKNZEWOE-UHFFFAOYSA-, MolPort-002-085-009, ZINC362579, HY-B2030, NSC31312, SMSF0001373, Tox21_201774, Tox21_300848, CCG-39416, N-(3,4-dichlorophenyl)-propionamide, NSC-31312, Propanil 10 microg/mL in Cyclohexane, AKOS002960411, CB01718, CS-5217, MCULE-7996228609, Propanil 10 microg/mL in Acetonitrile, NCGC00094523-01, NCGC00094523-02, NCGC00094523-03, NCGC00094523-04, NCGC00094523-05, NCGC00094523-06, NCGC00094523-07, NCGC00254751-01, NCGC00259323-01, AN-47379, SMR000778058, ZB011115, BIM-0000452.P001, KB-109322, LS-124363, TR-031892, FT-0603505, Propanil, PESTANAL(R), analytical standard, C14229, 33059-EP2274983A1, 33059-EP2305655A2, 33059-EP2311815A1, 33059-EP2371823A1, 709P988, AN-652/13319019, SR-01000221575, Q-201627, SR-01000221575-1, BRD-K08618283-001-02-0, 3 inverted exclamation marka,4 inverted exclamation marka-Dichloropropionanilide, 11096-32-5, InChI=1/C9H9Cl2NO/c1-2-9(13)12-6-3-4-7(10)8(11)5-6/h3-5H,2H2,1H3,(H,12,13)

ID: 1260

InChIKey: LGBHNNGNTSGBAA-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C3=CC=CC=C3OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"N Liu" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile" "J Liao" "C Pavel" "SM Anjos"

CID is 668965
synonyms found at PubChem are:
83863-44-9, 1-(2-Methoxyphenyl)-4-(p-tolylsulphonyl)piperazine, 1-(2-methoxyphenyl)-4-[(4-methylphenyl)sulfonyl]piperazine, 1-(2-methoxyphenyl)-4-(p-tolylsulfonyl)piperazine, EINECS 281-107-1, AC1LDLAA, BAS 00451426, Oprea1_277459, Oprea1_847731, ZINC29412, DTXSID30232756, MolPort-000-556-285, STK071381, AKOS000579076, 1-(2-Methoxyphenyl)-4-tosylpiperazine, MCULE-2377838737, UPCMLD0ENAT5802974:001, ST042463, KB-213254, AG-205/36815005, SR-01000514976, SR-01000514976-1, 1-(2-Methoxy-phenyl)-4-(toluene-4-sulfonyl)-piperazine, 1-(2-methoxyphenyl)-4-(4-methylphenyl)sulfonylpiperazine, A1271/0058149

ID: 1261

InChIKey: LHDWRKICQLTVDL-PZYDOOQISA-N
SMILES: C1=CO[C@H]([C@H]2[C@@H]1[C@@H]([C@H]3[C@@]2(O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 91520
synonyms found at PubChem are:
Catalpol, Catalpinoside, 2415-24-9, De(p-hydroxybenzoyl)catalposide, Catalposide, des-p-hydroxybenzoyl-, EINECS 219-324-0, CHEMBL513223, CHEBI:69797, (1AS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside, beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a-beta,6-beta,6a-alpha))-, beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-, AC1L3M8Y, SCHEMBL420515, Catalpol, >=96% (HPLC), DTXSID60178850, MolPort-028-744-577, HY-N0820, ZINC8234298, BDBM50259972, AKOS024264429, AC-8052, AM84820, AN-8406, CCG-208299, LMPR0102070007, NCGC00163523-01, LS-71485, N1352, SR-05000002315, I07-0187, SR-05000002315-2, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-|A-D-glucopyranoside, (1S,5R,6R)-2-[(1S,1bS,2S,5aR,6S)-6-hydroxy-1a-((S)-hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydro-1,3-dioxa-cyclopropa[a]inden-2-yloxy]-6-((S)-hydroxymethyl)-tetrahydro-pyran-3,4,5-triol, (2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,

ID: 1262

InChIKey: LHQLJMJLROMYRN-UHFFFAOYSA-L
SMILES: CC(=O)[O-].CC(=O)[O-].[Cd+2]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10986
synonyms found at PubChem are:
cadmium acetate, Cadmium diacetate, 543-90-8, Acetic acid, cadmium salt, Cadmium ethanoate, Bis(acetoxy)cadmium, Cadmium di(acetate), Cadmium(II) acetate, UNII-95KC50Z1L0, CCRIS 7783, HSDB 280, cadmium(2+) diacetate, Acetic acid, cadmium salt dihydrate, EINECS 208-853-2, NSC 75795, CI 77185, AI3-01414, AI3-02414, C.I. 77185, 95KC50Z1L0, Acetic acid, cadmium salt (2:1), Cadmium acetate [Cadmium and cadmium compounds], ACETIC ACID, CADMIUM SALT, DIHYDRATE, Cadmium (II) Acetate, AC1L1WDQ, SCHEMBL20830, Cadmium Acetate Anhydrous 98%, 5743-04-4 (dihydrate), DTXSID1020225, CTK5I4854, 22429-86-3 (trihydrate), LHQLJMJLROMYRN-UHFFFAOYSA-L, AKOS015915937, LS-1400, LS-7248, Cadmium acetate dihydrate, 98% 100g, AN-45787, DB-022999, FT-0623363, CADMIUM ACETATE DIHYDRATE (CHEMICAL MIXTURE), I14-52512, 24558-49-4, 245727-62-2, 29398-76-3

ID: 1263

InChIKey: LHYHMMRYTDARSZ-BYNSBNAKSA-N
SMILES: CC1=C[C@H]2[C@@H](CC[C@@]([C@@H]2CC1)(C)O)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10398656
synonyms found at PubChem are:
alpha-Cadinol, Cadin-4-en-10-ol, 481-34-5, UNII-DC0YJ4816P, DC0YJ4816P, l-alpha-Cadinol, (1R,4S,4aR,8aR)-4-Isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-ol, (-)-alpha-Cadinol, alpha-Cadinol, (-)-, CHEMBL486795, SCHEMBL4276031, CHEBI:132905, (1R,4S,4aR,8aR)-1,6-dimethyl-4-(propan-2-yl)-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-ol

ID: 1264

InChIKey: LIIALPBMIOVAHH-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C=CC(=O)O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10748
synonyms found at PubChem are:
7-Methoxycoumarin, Herniarin, 531-59-9, 7-Methoxy-2H-chromen-2-one, Ayapanin, Herniarine, Methylumbelliferone, 7-Methoxy-2H-1-benzopyran-2-one, 7-methoxychromen-2-one, 2H-1-BENZOPYRAN-2-ONE, 7-METHOXY-, Coumarin, 7-methoxy-, METHOXYCOURMARIN, 7-, Herniarin (6CI), Methyl umbelliferyl ether, UNII-DGK72G008A, 7-methoxy-coumarin, 7-Methoxy Coumarin, NSC 404559, 7-(methyloxy)-2H-chromen-2-one, 7-methoxy-chromen-2-one, EINECS 208-513-3, BRN 0141728, CHEMBL49732, CHEBI:5679, DGK72G008A, Coumarin, 7-methoxy- (8CI), LIIALPBMIOVAHH-UHFFFAOYSA-N, 7-Methyl ether derivative of Umbelliferone, M-3330, 7-Methoxycoumarin, >=98%, 7-methoxy-1-benzopyran-2-one, SMR000156201, Herniarin,(S), Spectrum_000392, 7-O-methylumbelliferone, SpecPlus_000322, Spectrum2_000398, Spectrum3_000263, Spectrum4_001558, Spectrum5_000156, 7-METHOXYCOURMARIN, Umbelliferone methyl ether, ACMC-1ADZ9, D0U4BB, Umbelliferone, methyl ether, AC1L1VV5, SCHEMBL61221, BSPBio_001706, KBioGR_002056, KBioSS_000872, SPECTRUM210874, 5-18-01-00387 (Beilstein Handbook Reference), MLS000563125, MLS000574914, DivK1c_006418, SPBio_000615, MEGxp0_000150, DTXSID5060196, ACon1_002037, CTK1D5789, KBio1_001362, KBio2_000872, KBio2_003440, KBio2_006008, KBio3_001206, 7-Methoxy-2H-chromen-2-one #, MolPort-000-881-224, HMS2271N13, ZINC391177, HY-N1366, KS-000010MG, ZX-AT016183, ANW-31646, BDBM50303499, CCG-38669, MFCD00006876, NSC404559, STK374268, 7-Methoxycoumarin, analytical standard, AKOS000277129, ACM4003898, FCH1112129, MCULE-4358069418, NSC-404559, SDCCGMLS-0066524.P001, NCGC00095528-01, NCGC00095528-02, NCGC00095528-03, NCGC00179069-01, NCGC00179069-02, 7-Methoxy-2H-1-benzopyran-2-one, 9CI, AJ-21051, AK135155, AN-23549, KB-85946, LS-39737, AX8012761, TR-036997, 4CH-024958, CS-0016775, FT-0621446, M1723, ST24045687, ST50406549, V1412, A-8170, C09268, A824863, A829418, SR-01000712094, Herniarin, primary pharmaceutical reference standard, SR-01000712094-2, BRD-K81209159-001-02-9, I14-13448, I14-29054, Z53852417, 1,?2,?3,?4-?tetrahydro-?7-?methoxy-2-?Naphthalenamine, 7-Methoxycoumarin, suitable for fluorescence, >=98.0% (TLC)

ID: 1265

InChIKey: LJDRQPOQHHOXHM-HIFRSBDPSA-N
SMILES: CCCN1CC[C@H]2[C@@H]1CCC3=C2C=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10353845
synonyms found at PubChem are:
cis8-OH-PBZI hydrobromide, cis-8-oh-pbzi, 8-OH-PBZI, Lopac0_000935, CHEMBL1618335, SCHEMBL15938228, cis-(+/-)-8-OH-PBZI hydrobromide, CCG-205016, NCGC00162237-01, NCGC00162237-02, NCGC00162237-03, 2,3,3aalpha,4,5,9balpha-Hexahydro-3-propyl-1H-benz[e]indol-8-ol

ID: 1266

InChIKey: LJJKNPQAGWVLDQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3132
synonyms found at PubChem are:
THIORPHAN, dl-thiorphan, 76721-89-6, DL-3-Mercapto-2-benzylpropanoylglycine, 2-[(2-benzyl-3-sulfanylpropanoyl)amino]acetic acid, n-(2-benzyl-3-sulfanylpropanoyl)glycine, CHEMBL10247, CHEBI:9568, 2-(2-Benzyl-3-mercaptopropanamido)acetic acid, Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-, (DL-3-Mercapto-2-benzylpropanoyl)-Gly-OH, N-[(RS)-2-Benzyl-3-mercaptopropanoyl]-glycine, C12H15NO3S, Tiorphan, SR-01000076164, Prestwick_694, (3-Mercapto-2-benzylpropionyl)glycine, ACMC-20eo1l, AC1Q5WMR, Prestwick0_000633, Prestwick1_000633, Prestwick2_000633, Prestwick3_000633, AC1L1F8Q, AC1Q75XI, Lopac0_001139, BSPBio_000626, BSPBio_001543, KBioGR_000263, KBioSS_000263, MLS002153923, SCHEMBL401174, SPBio_002845, BPBio1_000690, BDBM21641, KBio2_000263, KBio2_002831, KBio2_005399, KBio3_000525, KBio3_000526, MolPort-003-850-539, Bio2_000263, Bio2_000743, DL-Thiorphan, >=98% (TLC), ES 52, ES-52, HMS1361N05, HMS1569P08, HMS1791N05, HMS1989N05, HMS2096P08, HMS2230G03, HMS3263D19, HMS3373F16, HMS3402N05, HMS3713P08, Tox21_501139, MFCD00058435, NSC727676, AKOS024257670, API0000859, CCG-205213, LP01139, NSC-727676, TRA0084177, IDI1_034013, SMP2_000064, N-(2-Benzyl-3-mercaptopropanoyl)glycine, NCGC00016033-02, NCGC00016033-03, NCGC00016033-04, NCGC00016033-05, NCGC00016033-06, NCGC00094405-01, NCGC00094405-02, NCGC00094405-03, NCGC00094405-04, NCGC00261824-01, SMR001233267, DL-3-Mercapto-2-benzyl-propanoyl]-glycine, KB-125384, LS-177293, TX-018022, EU-0101139, FT-0675192, DL- 3-Mercapto-2-benzyl- propanoyl]-glycine, 2-(2-benzyl-3-sulfanylpropanamido)acetic acid, C01619, T 6031, (+/-)-N-(3-Mercapto-2-benzylpropionyl)glycine, C-46207, SR-01000076164-1, SR-01000076164-5, 2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid, BRD-A56012032-001-06-4, 2-[[2-(phenylmethyl)-3-sulfanylpropanoyl]amino]acetic acid, Racecadotril active metabolite|||Acetorphan active metabolite, ( inverted exclamation markA)-N-(3-Mercapto-2-benzylpropionyl)glycine

ID: 1267

InChIKey: LJMFGBZVIQCIAV-UHFFFAOYSA-N
SMILES: CC1(CCC2=C(O1)C=CC(=C2OC)C(=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3548249
synonyms found at PubChem are:
DIHYDRO-beta-TUBAIC ACID, KBio2_000958, Spectrum_000478, SpecPlus_000648, AC1MTC4X, Spectrum2_001168, Spectrum3_001798, Spectrum4_001577, Spectrum5_000234, BSPBio_003355, KBioGR_002134, KBioSS_000958, DivK1c_006744, SPBio_001155, CHEMBL3039222, CHEBI:93694, KBio1_001688, KBio2_003526, KBio2_006094, KBio3_002857, CCG-39669, BRD-K96362535-001-02-4, 5-methoxy-2,2-dimethyl-3,4-dihydrochromene-6-carboxylic acid

ID: 1268

InChIKey: LJOWVFVITGCFAG-UHFFFAOYSA-M
SMILES: [NH0+](C(C1=CC=CC=C1)CO)1C=CC=CC=1.[ClH0-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 15678602
synonyms found at PubChem are:
SCHEMBL7922158

ID: 1269

InChIKey: LJSBBBWQTLXQEN-UHFFFAOYSA-N
SMILES: CCCN1C(=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4273754
synonyms found at PubChem are:
JWH-015, 155471-08-2, JWH 015, UNII-W4FL204T10, (2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone, JWH015, (2-methyl-1-propylindol-3-yl)-naphthalen-1-ylmethanone, CHEMBL306764, W4FL204T10, MFCD02094630, (2-methyl-1-propyl-1H-indol-3-yl)(naphthalen-1-yl)methanone, JHW 015, SR-01000597570, (2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone, JHW-015, NCGC00025117-01, PubChem19328, Tocris-1341, D0YZ8I, MLS002153392, SCHEMBL497044, AC1N784D, GTPL5558, BDBM21282, CHEBI:92318, AOB5643, DTXSID60165902, LJSBBBWQTLXQEN-UHFFFAOYSA-N, MolPort-003-983-602, HMS2236B06, HMS3267P11, HMS3373A11, HMS3650K06, ACT06815, Methanone, (2-methyl-1-propyl-1H-indol-3-yl)-1-naphthalenyl-, ZINC2577049, AKOS015909302, CCG-208734, SMR001230773, JWH-015, >=98% (HPLC), powder, FT-0670586, 471J082, SR-01000597570-1, SR-01000597570-3, BRD-K17796732-001-02-0, I14-33000, JWH-015 (1-propyl-2-methyl-3-(1-napthoyl)indole), 2-methyl-3-(naphthalen-1-ylcarbonyl)-1-propyl-1H-indole, (2-methyl-1-propyl-1H-indol-3-yl)-1-naphthalenyl-Methanone, JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone), JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone) 0.1 mg/ml in Acetonitrile, JWH-015 ((2-Methyl-1-propylindol-3-yl)(naphthalen-1-yl)methanone) 1.0 mg/ml in Acetonitrile

ID: 1270

InChIKey: LJUNPHMOGNFFOS-UHFFFAOYSA-N
SMILES: C1CCN(CC1)C(=O)C2=CC3=C(C=C2)OCCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2890
synonyms found at PubChem are:
215923-54-9, CX 546, CX546, CX-546, 1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine, (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(piperidin-1-yl)methanone, UNII-PV6YEC8983, BDP 17, PV6YEC8983, 2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone, CHEMBL1255648, GR 87, Methanone,(2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-, (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone, 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)carbonyl]piperidine, Lopac-C-271, AC1L1EPB, AC1Q5EMV, CBMicro_029090, D0G3AR, Cambridge id 5708417, Lopac0_000394, Oprea1_361155, MLS000108057, SCHEMBL244490, BDP-17, GTPL4166, ZINC9070, CTK4E7220, AOB6689, DTXSID70175951, MolPort-000-391-923, GR-87, HMS2184B08, HMS3261O09, BCP23921, Tox21_500394, 2848AH, CX-717, CX-727, CX-729, CX-743, CX-815, MFCD01860868, STK205195, AKOS002821597, API0008302, CCG-204095, CS-3628, CX-1763, LP00394, MCULE-7079467998, RTC-072261, KS-0000186Q, SEL11071486, CX546, >=98% (HPLC), solid, NCGC00015200-01, NCGC00015200-02, NCGC00015200-03, NCGC00015200-04, NCGC00015200-05, NCGC00078109-02, NCGC00078109-03, NCGC00261079-01, AJ-08326, HY-12505, SMR000104020, BIM-0028924.P001, DB-066568, KB-308463, TC-072261, B7240, C-271, EU-0100394, FT-0665238, ST45184346, 923C549, S-40929, SR-01000075430, AMPAKINE compound (respiratory depression), Valeant, J-014162, SR-01000075430-1, I14-13062, 2H,3H-benzo[3,4-e]1,4-dioxin-6-yl piperidyl ketone, 2,3-Dihydro-1,4-benzodioxin-7-yl-(1-piperidyl)methanone, AMPAKINE compound (respiratory depression), BiovailLaboratories, Methanone, (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-, Piperidine, 1-((2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl)-, First-generation AMPAKINE compounds, University of California/Cortex, First generation AMPA receptor modulators, Cortex/University of California

ID: 1271

InChIKey: LKHRMULASXZCLG-UHFFFAOYSA-N
SMILES: CCN1C2=CC(=C(C=C2NC1=O)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 656765
synonyms found at PubChem are:
DCEBIO, 60563-36-2, dichloro-EBIO, 5,6-Dichloro-1-ethyl-1H-benzo[d]imidazol-2(3H)-one, DC-EBIO, 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, 5,6-dichloro-3-ethyl-1H-benzimidazol-2-one, CHEBI:34662, 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazole-2-one, SR-01000075842, Tocris-1422, AC1LCVJ8, Lopac-D-9190, D0I6MA, C13844, Lopac0_000434, MLS002153394, SCHEMBL612079, GTPL2324, ZINC8902, CHEMBL1255655, CTK8F8980, DTXSID50349653, MolPort-003-941-196, HMS2236K06, HMS3261G10, HMS3267J10, HMS3369H21, Tox21_500434, AB1381, BN0170, MFCD04040030, AKOS016845843, DCEBIO, >=98% (HPLC), solid, API0008456, CCG-204526, FCH1366780, LP00434, NCGC00015382-01, NCGC00015382-02, NCGC00015382-03, NCGC00015382-04, NCGC00015382-05, NCGC00025157-01, NCGC00025157-02, NCGC00025157-03, NCGC00261119-01, AJ-08321, AS-44571, EN000162, SMR001230775, AX8123528, KB-111236, B6733, EU-0100434, D 9190, SR-01000075842-1, SR-01000075842-3, 5,6-Dichloro-1-ethyl-1Hbenzo[d]imidazol-2(3H)-one, BRD-K32526544-001-01-2, 2H-Benzimidazol-2-one,5,6-dichloro-1-ethyl-1,3-dihydro-, 5,6-Dichloro-1-ethyl-1,3-dihydro- 2H-benzimidazol-2-one

ID: 1272

InChIKey: LKHWKAGQNOMUFQ-UHFFFAOYSA-N
SMILES: CCCNC(C)(C)COC(=O)C1=CC=CC=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 101925
synonyms found at PubChem are:
Meprylcaine hydrochloride, Oracaine hydrochloride, Meprylcaine HCl, 956-03-6, UNII-VR843X5GXG, EINECS 213-475-6, VR843X5GXG, E-17-2, 2-Methyl-2-(propylamino)-1-propanol benzoate hydrochloride, 2-Methyl-2-(propylamino)-1-propanol benzoate (ester) hydrochloride, 1-Propanol, 2-methyl-2-(propylamino)-, benzoate (ester), hydrochloride, DSSTox_CID_25341, DSSTox_RID_80809, C14H21NO2.HCl, DSSTox_GSID_45341, (2-(Benzoyloxy)-1,1-dimethylethyl)propylammonium chloride, 1-Propanol-2-methyl-2-(propylamino)-, benzoate (ester), hydrochloride, 1-Propanol, 2-methyl-2-(propylamino)-, 1-benzoate, hydrochloride (1:1), 2-methyl-2-(propylamino)propyl benzoate, chloride, NCGC00016551-01, CAS-956-03-6, Meprylcaine hydrochloride [USP], Oracaine (TN), AC1L2RT5, MLS002154137, SCHEMBL467368, CHEMBL2104800, DTXSID4045341, Meprylcaine hydrochloride (JAN), CHEBI:31820, HMS1571E10, Pharmakon1600-01505553, Tox21_110489, NSC760071, SBB058164, AKOS024374959, Tox21_110489_1, CCG-213482, MCULE-3774545156, NSC-760071, NCGC00016551-04, SMR001233444, LS-122578, ST51015051, D01417, SR-01000841208, SR-01000841208-2, [2-methyl-2-(propylamino)propyl] benzoate hydrochloride

ID: 1273

InChIKey: LKMNXYDUQXAUCZ-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 145659
synonyms found at PubChem are:
Sinensetin, 2306-27-6, 5,6,7,3',4'-Pentamethoxyflavone, 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one, 3',4',5,6,7-Pentamethoxyflavone, Pedalitin permethyl ether, UNII-240LNZ51AT, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-, 240LNZ51AT, CHEBI:9159, CHEMBL226507, 27181-91-5, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxychromen-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one, SR-05000002257, AC1L3RN3, SCHEMBL621101, MEGxp0_000957, CTK4F9237, DTXSID60177626, LKMNXYDUQXAUCZ-UHFFFAOYSA-N, MolPort-001-741-112, HY-N0297, ZINC1531698, 3`,4`,5,6,7-Pentamethoxyflavone, BDBM50338975, LMPK12111250, AKOS016009570, API0004181, CCG-208419, CS-5907, VA11761, Flavone, 5,6,7,3',4'-pentamethoxy, 3'',4'',5,6,7-pentamethoxy flavone, 5,6,7,3'',4'' -pentamethoxyflavone, NCGC00163623-01, AJ-26732, AN-50682, BC282855, CJ-24105, DB-046067, KB-221448, KB-221449, TR-010778, FT-0634191, N2560, ST24039240, ST50331679, X1234, C10186, 306S276, A816546, C-57750, SR-05000002257-2, SR-05000002257-3, BRD-K84996949-001-01-5, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-1-benzopyran-4-one, 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one #

ID: 1274

InChIKey: LKPINBXAWIMZCG-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5763
synonyms found at PubChem are:
Adiphenine hydrochloride, 50-42-0, ADIPHENINE HCL, Patrovina, Sentiv, Spasnil, Trasentin hydrochloride, Adiphenine chloride, Adiphen hydrochloride, Difacil hydrochloride, Vegantin, Adifenin hydrochloride, Diphacil hydrochloride, Trasentine hydrochloride, Transentine hydrochloride, Adiphenine (hydrochloride), Adipheninium chloratum, Spasmolytin hydrochloride, UNII-42B4PDY0AV, Diphenylacetic acid 2-(diethylamino)ethyl ester hydrochloride, 2-(Diethylamino)ethyl diphenylacetate hydrochloride, Adiphenine hydrochloride [USAN], Diphenylacetyldiethylaminoethyl hydrochloride, EINECS 200-036-9, NSC 129224, 42B4PDY0AV, MLS000028404, Diphenylacetate du diethylamino-ethanol chlorhydrate, NCGC00094995-01, Diphenylacetate du diethylamino-ethanol chlorhydrate [French], SMR000058354, Ethanol, 2-(diethylamino)-, 2,2-diphenylacetate, hydrochloride, Benzeneacetic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride, DSSTox_CID_25880, DSSTox_RID_81196, DSSTox_GSID_45880, 2-(diethylamino)ethyl 2,2-diphenylacetate hydrochloride, Adiphenine hydrochloride (USAN), ACETIC ACID, DIPHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE, Benzeneacetic acid, alpha-phenyl-2-(diethylamino)ethyl ester hydrochloride, NSC129224, CAS-50-42-0, 2-(diethylamino)ethyl 2,2-diphenylacetate, chloride, 2-(diethylamino)ethyl 2,2-diphenylacetate;hydrochloride, SR-01000000075, Prestwick_7, AdiphenineHydrochloride, Opera_ID_604, Trasentine, hydrochloride, REGID_for_CID_5763, SCHEMBL33478, MLS001076478, MLS002222150, SPECTRUM1503073, AC1L1L32, CHEMBL555654, DTXSID0045880, CTK8F7607, HY-B0379A, MolPort-002-132-736, HMS1568O11, HMS1922C11, Pharmakon1600-01503073, WLN: 2N2&2OVYR&R &GH, BCP22622, KS-000014SY, Tox21_111379, AC-013, CCG-39173, NSC758234, s2082, SBB058125, AKOS015900392, Tox21_111379_1, API0007144, CS-2449, MCULE-8659491808, NSC-129224, NSC-758234, VA10175, NCGC00016221-06, NCGC00094995-02, NCGC00094995-03, AK343579, AN-16208, AS-15686, LS-11887, Q263, SC-24971, AB0017479, AB2000486, Adiphenine hydrochloride, analytical standard, Ethanol, 2,2-diphenylacetate, hydrochloride, FT-0657379, ST51014890, D02772, K-9333, 2-Diethylaminoethyl diphenylacetate hydrochloride, A828115, I14-0944, SR-01000000075-4, 2-diethylaminoethyl 2,2-diphenylacetate hydrochloride, 2-(diethylamino)ethyl 2,2-diphenylethanoate hydrochloride, 2,2-diphenylacetic acid 2-(diethylamino)ethyl ester hydrochloride, Benzeneacetic acid, .alpha.-phenyl-2-(diethylamino)ethyl ester hydrochloride, Benzeneacetic acid, a-phenyl-, 2-(diethylamino)ethyl ester,hydrochloride, AC1LCWCJ, AKOS026749779, 2-diethylaminoethyl 2,2-diphenylacetate; hydron; chloride, MolPort-000-708-273

ID: 1275

InChIKey: LKPQNZRGGNOPPU-UHFFFAOYSA-N
SMILES: COC1=C(OC2=C(C1=O)C=CC3=C2C=CO3)C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 100633
synonyms found at PubChem are:
Karanjin, 521-88-0, 3-methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one, UNII-WV7IM0I02M, WV7IM0I02M, 3-methoxy-2-phenyl-4h-furo[2,3-h]chromen-4-on, C18H12O4, NSC335755, 3-methoxy-2-phenylfuro[2,3-h]chromen-4-one, 3-methoxy-2-phenyl-furo[2,3-h]chromen-4-one, 7-Methoxy-8-phenylfurano[2,3-h]chromen-6-one, 4H-Furo[2,3-h]-1-benzopyran-4-one, 3-methoxy-2-phenyl-, Kranjin, EINECS 208-319-9, NSC 335755, FLAVONE (BOHLMAN), AC1L2P5L, AC1Q6IT4, MLS001360608, BIDD:ER0513, SCHEMBL247164, CHEMBL208484, MEGxp0_001687, CTK8D5001, ZINC39119, DTXSID20200106, Karanjin from Pongamia glabra oil, LKPQNZRGGNOPPU-UHFFFAOYSA-N, MolPort-004-955-030, HMS3043B17, TNP00046, 4H-Furo[2, 3-methoxy-2-phenyl-, 7332AB, LMPK12111542, AKOS016010124, MCULE-6473864283, NSC-335755, Karanjin 100 microg/mL in Acetonitrile, NCGC00017182-01, NCGC00017182-02, NCGC00017182-03, NCGC00142418-01, AJ-08828, CC-29752, SMR001223861, ST055657, ZB001097, AX8135542, KB-236450, 4CH-024654, FT-0603444, Karanjin, disposable screening library format, ST24042261, C-18336, A1-03165, 3-methoxy-2-phenyl-4H-furo(2,3-h)-1-benzopyran-4-one, 3-Methoxy-2-phenyl-4H-furo(2,3-h)(1)benzopyran-4-one, 4H-Furo(2,3-h)-1-benzopyran-4-one, 3-methoxy-2-phenyl- (8CI)(9CI)

ID: 1276

InChIKey: LKUDPHPHKOZXCD-UHFFFAOYSA-N
SMILES: COC1=CC(=CC(=C1)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 69301
synonyms found at PubChem are:
1,3,5-Trimethoxybenzene, 621-23-8, Phloroglucinol trimethyl ether, sym-Trimethoxybenzene, Benzene, 1,3,5-trimethoxy-, 1,3,5-Trimethyoxybenzene, UNII-00VJI3VG3D, O,O,O-1,3,5-Trimethylresorcinol, EINECS 210-673-4, NSC 90060, 1,3,5-Trimethoxy benzene, BRN 1307993, 00VJI3VG3D, CHEBI:31038, LKUDPHPHKOZXCD-UHFFFAOYSA-N, NCGC00095239-01, DSSTox_CID_25963, DSSTox_RID_81259, DSSTox_GSID_45963, CAS-621-23-8, 1,5-Trimethoxybenzene, PubChem16522, Spectrum_001404, 1,5-Trimethyoxybenzene, 1,3,5-trimethoxybenzol, Spectrum2_000426, Spectrum3_001030, Spectrum4_001163, Spectrum5_001766, ACMC-1BB8M, 1,3,5 -trimethoxybenzene, 1,3,5-trimethoxy-benzene, 2,4,6-Trimethoxy-benzene, AC1L2BK8, NCIOpen2_001419, SCHEMBL28493, BSPBio_002819, KBioGR_001765, KBioSS_001884, SPECTRUM231043, 4-06-00-07362 (Beilstein Handbook Reference), KSC352Q2R, MLS002207155, SPBio_000412, CHEMBL1605492, DTXSID0045963, CTK2F2828, KBio2_001884, KBio2_004452, KBio2_007020, KBio3_002039, KS-00000EWX, 1,3,5-Trimethoxybenzene (JAN), MolPort-001-759-537, HMS1763E15, HMS1923E11, ZINC388241, ACT04949, NSC90060, Tox21_111489, ANW-34066, CCG-39953, CT0057, MFCD00008385, NSC-90060, AKOS000120577, Tox21_111489_1, AS04446, CS-W009141, MCULE-9726275673, MP-2133, RL04359, RP23091, RTR-021353, TRA-0189713, 1,3,5-Trimethoxybenzene, 99% 10g, NCGC00095239-02, NCGC00095239-03, NCGC00095239-05, AJ-20506, AN-21987, AS-10870, CJ-03164, KB-10233, LS-32251, SC-17623, SMR001306732, ZB011378, AB0007050, AB1008241, ST2414784, TL8004038, TR-021353, FT-0606514, P0250, ST50406630, D01792, A833592, 1,3,5-Trimethoxybenzene, ReagentPlus(R), >=99%, I01-2537, Q-200071, BRD-K81884069-001-02-8, BRD-K81884069-001-03-6, 1,3,5-Trimethoxybenzene, Vetec(TM) reagent grade, 98%, UNII-5PPX04J036 component LKUDPHPHKOZXCD-UHFFFAOYSA-N, 1,3,5-Trimethoxybenzene, Standard for quantitative NMR, TraceCERT(R), InChI=1/C9H12O3/c1-10-7-4-8(11-2)6-9(5-7)12-3/h4-6H,1-3H

ID: 1277

InChIKey: LLBLNMUONVVVPG-UHFFFAOYSA-N
SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CC3=CNC4=CC=CC=C43

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 133633
synonyms found at PubChem are:
L-741,626, 81226-60-0, L-741626, 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole, L 741626, L 741,626, CHEMBL445102, 4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol, 4-(4-chlorophenyl)-1-(1h-indol-3-ylmethyl)piperidin-4-ol, C20H21ClN2O, 4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-, SR-01000075973, NCGC00015591-01, Tocris-1003, Lopac-L-135, Biomol-NT_000036, D0M3PV, AC1Q3NO6, Lopac0_000742, GTPL177, MLS000860079, AC1L335F, BPBio1_001094, ZINC6788, SCHEMBL11253588, CHEBI:92090, CTK3I9542, DTXSID30230974, LLBLNMUONVVVPG-UHFFFAOYSA-N, MolPort-003-943-618, HMS2230F17, HMS3262E06, HMS3267M15, HMS3370K05, KUC112479N, Tox21_500742, BDBM50050467, MFCD00953632, PDSP1_001415, PDSP1_001848, PDSP2_001399, PDSP2_001833, AKOS024456330, CCG-204827, LP00742, NCGC00015591-02, NCGC00015591-03, NCGC00015591-04, NCGC00015591-05, NCGC00015591-06, NCGC00015591-07, NCGC00024932-01, NCGC00024932-02, NCGC00024932-03, NCGC00024932-04, NCGC00261427-01, KSC-315-034-, SMR000326937, LS-116920, B6544, EU-0100742, L-135, A19235, L000887, L741626, L-741,626, >=98% (HPLC), L741,626, SR-01000075973-1, SR-01000075973-3, BRD-K05181463-001-01-6, BRD-K05181463-001-04-0, 3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole, 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol, 4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol, (+/-)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole, 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole, 4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL, ( inverted exclamation markA)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole, ( inverted question mark)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole

ID: 1278

InChIKey: LLJFMFZYVVLQKT-UHFFFAOYSA-N
SMILES: CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 91610
synonyms found at PubChem are:
Gliquidone, 33342-05-1, Glurenorm, Beglynor, Gliquidonum, glikvidon, glycvidon, Beglynora, Gliquidona, Gliquidonum [INN-Latin], Gliquidona [INN-Spanish], ARDF 26 SE, ARDF 26, Gliquidone [BAN:INN], C27H33N3O6S, UNII-C7C2QDD75P, Glurenorm (TN), Gliquidone (INN), AR-DF 26, Gliquidone sodium, EINECS 251-463-2, BRN 1559726, C7C2QDD75P, MFCD00631870, 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea, NCGC00016819-01, CAS-33342-05-1, DSSTox_CID_3096, DSSTox_RID_76873, DSSTox_GSID_23096, 1-Cyclohexyl-3-((p-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl)phenyl)sulfonyl)urea, 1-Cyclohexyl-3-(p-beta-(4,4-dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione-2-yl)phenethyl)sulfonylurea, 3-Cyclohexyl-1-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-isoquinolin-2-yl)ethyl]phenyl]sulfonyl-urea, Benzenesulfonamide, N-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl)-, N-(Cyclohexylcarbamoyl)-4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)benzenesulfonamide, 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-2-isoquinolinyl)ethyl]phenyl]sulfonylurea, N-[(cyclohexylamino)carbonyl]-4-{2-[4,4-dimethyl-7-(methyloxy)-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl]ethyl}benzenesulfonamide, SMR000685793, Gliquidone [INN:BAN], Gliquidon, gliquidone calcium, Gliquidone,(S), gliquidone monosodium, AC1L3MFD, Prestwick0_000991, Prestwick1_000991, Prestwick2_000991, Prestwick3_000991, D06HBQ, Oprea1_069443, SCHEMBL37769, ARDF-26, BSPBio_001081, MLS000881123, MLS000881174, MLS002154087, SPBio_002972, BPBio1_001191, CHEMBL383634, DTXSID4023096, CHEBI:93416, CTK8B3534, KS-00000XIQ, MolPort-001-727-724, HMS1571G03, HMS2098G03, HMS2964J06, HMS3652O05, HMS3715G03, ACT06290, BCP11927, HY-B1114, ZINC1482077, Tox21_110629, ANW-42682, CG0041, AKOS001037880, Tox21_110629_1, API0002843, CCG-220991, CM14378, CS-4646, DB01251, KS-5239, MCULE-6775445815, NCGC00016819-02, NCGC00016819-03, NCGC00016819-05, NCGC00016819-06, NCGC00179315-01, 1-cyclohexyl-3-(p-beta-(4,4- dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione- 2-yl)phenethyl)sulfonylurea, 62783-47-5 (mono-hydrochloride salt), AC-23356, BC214705, CC-28983, LS-31460, SC-13574, LS-159650, N-(cyclohexylcarbamoyl)-4-(2-(7-methoxy-, TL8002523, TR-013968, AB00513989, FT-0630570, G0332, S3151, D02430, J10245, 4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin, AB00513989_07, 342G051, A821736, C-23093, SR-01000833866, I06-0185, J-019153, SR-01000833866-2, BRD-K80396088-001-03-9, 1-cyclohexyl-3-[4-[2-[7-methoxy-4,4-dimethyl-1,3-bis(oxidanylidene)isoquinolin-2-yl]ethyl]phenyl]sulfonyl-urea, 3-cyclohexyl-1-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea, 3-cyclohexyl-1-{4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]benzenesulfonyl}urea

ID: 1279

InChIKey: LLLIKVGWTVPYAL-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)OC(=CC2=O)C3=CC(=CC=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 676293
synonyms found at PubChem are:
6,3'-DIMETHOXYFLAVONE, 79786-40-6, 6-methoxy-2-(3-methoxyphenyl)chromen-4-one, KBio2_003693, Spectrum_000645, SpecPlus_000160, AC1LDWB2, Spectrum2_000031, Spectrum3_001624, Spectrum4_001729, Spectrum5_000498, BSPBio_003287, KBioGR_002118, KBioSS_001125, DivK1c_006256, SCHEMBL516389, SPBio_000121, CHEMBL3039144, CTK5E7120, KBio1_001200, KBio2_001125, KBio2_006261, KBio3_002507, ZINC39296, DTXSID50350264, CHEBI:107657, LLLIKVGWTVPYAL-UHFFFAOYSA-N, 6,3'-dimethoxyflavone, AldrichCPR, CCG-38344, LMPK12110103, AKOS024282378, MCULE-5250744070, SDCCGMLS-0066760.P001, NCGC00178161-01, ST055989, ZB001111, FT-0726184, J3.582.267D, 6-methoxy-2-(3-methoxyphenyl)-4H-chromen-4-one, C-56385, SR-05000002533, SR-05000002533-1, BRD-K47724892-001-02-2, BRD-K47724892-001-03-0, 2-(3-Methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one,6-methoxy-2-(3-methoxyphenyl)-, 4H-1-Benzopyran-4-one, 6-methoxy-2-(3-methoxyphenyl)-

ID: 1280

InChIKey: LMEKQMALGUDUQG-UHFFFAOYSA-N
SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2265
synonyms found at PubChem are:
azathioprine, 446-86-6, Azothioprine, Imuran, Azathioprin, Azatioprin, Azamun, Azanin, Imurel, Azathiopurine, Ccucol, Imurek, Muran, Azasan, Azamun [Czech], Azathioprine sodium, Azatioprina, Cytostatics, BW 57-322, BW-57-322, Immuran, NCI-C03474, NSC-39084, Azathioprinum [INN-Latin], Azatioprina [INN-Spanish], Imuran (TN), NSC 39084, Azamune, 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine, 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine, azatiopr in, Methylnitroimidazolylmercaptopurine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine, UNII-MRK240IY2L, CCRIS 62, C9H7N7O2S, 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine, Azasan (TN), Azathioprine (Azasan, Imuran), 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-, Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-, HSDB 7084, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine, 6-(Methyl-p-nitro-5-imidazolyl)-thiopurine, Azathioprine [USAN:INN:BAN:JAN], EINECS 207-175-4, 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-, 6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine, MRK240IY2L, 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech], BW 57322, AI3-50290, 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine, CHEBI:2948, 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin, B. W. 57-322, LMEKQMALGUDUQG-UHFFFAOYSA-N, NSC39084, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine, Purine, 6-((1-methyl-4-nitroimidazol-5-yl)thio)-, 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine, [Methyl(nitroimidazolyl)mercaptopurine], 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine, NCGC00015060-06, NCGC00015060-14, CAS-446-86-6, 6-(Methyl-p-nitro-5-imidazolyl)thiopurine, DSSTox_CID_119, 6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine, A 4638, Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl), 6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine, DSSTox_RID_75381, DSSTox_GSID_20119, 6-[(1-Methyl-4-nitroimidazol-5-yl)-thio] purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-7H-purine, 6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine, Azathioprine Sulfate, SR-01000075537, Purine, 6-[(1-methyl-4-nitroimidazol-5-yl)thio]-, 6-(1-methyl-4-nitro-1H-imidazol-5-ylthio)-9H-purine, azanine, azathropine, Azothioprin, Azoran, Prestwick_41, Azathiopurine,(S), Azamun (TN), Imurel (TN), PubChem9256, Azathioprine [USAN:USP:INN:BAN:JAN], Spectrum_000064, Azathioprine, >=98%, AC1L1DAL, Prestwick0_000094, Prestwick1_000094, Prestwick2_000094, Prestwick3_000094, Spectrum2_000068, Spectrum3_000308, Spectrum4_000243, Spectrum5_000848, Lopac-A-4638, Azasan, Imuran and others, ChemDiv1_002659, D07QCE, AC1Q3Z1F, SCHEMBL4278, CHEMBL1542, Lopac0_000027, Oprea1_375441, Oprea1_533384, Oprea1_633462, Azathioprine(Azasan, Imuran), BSPBio_000048, BSPBio_001876, CBDivE_013132, KBioGR_000646, KBioGR_002427, KBioSS_000464, KBioSS_002433, MLS001049307, DivK1c_000586, SPECTRUM1500133, SPBio_000255, SPBio_001987, BPBio1_000054, GTPL7120, DTXSID4020119, Azathioprine (JP15/USP/INN), Azathioprine (JP17/USP/INN), HMS501N08, HMS594I19, KBio1_000586, KBio2_000464, KBio2_002427, KBio2_003032, KBio2_004995, KBio2_005600, KBio2_007563, KBio3_001376, KBio3_002906, KS-00000XLZ, cMAP_000046, MolPort-000-745-914, MolPort-000-764-262, NINDS_000586, HMS1568C10, HMS1920E17, HMS2091K19, HMS2095C10, HMS2802J03, HMS3259P03, HMS3260E15, HMS3655M04, HMS3712C10, Pharmakon1600-01500133, ACT02232, BCP09492, HY-B0256, ZINC4258316, Tox21_110074, Tox21_400024, Tox21_500027, BDBM50373919, BG0097, CCG-16168, CCG-39877, GP1145, LS-123, MFCD00069203, NSC755900, s1721, STK831906, 55774-33-9 (hydrochloride salt), AKOS005609209, AKOS022184498, AKOS028108935, Tox21_110074_1, AC-4230, API0001569, CCG-220094, CS-2241, DB00993, KS-1146, LP00027, MCULE-8637589610, NC00614, NSC-755900, SDCCGMLS-0065415.P001, IDI1_000586, NCGC00015060-01, NCGC00015060-02, NCGC00015060-03, NCGC00015060-04, NCGC00015060-05, NCGC00015060-07, NCGC00015060-08, NCGC00015060-09, NCGC00015060-10, NCGC00015060-11, NCGC00015060-12, NCGC00015060-13, NCGC00015060-15, NCGC00015060-16, NCGC00015060-18, NCGC00015060-19, NCGC00090836-01, NCGC00090836-02, NCGC00090836-03, NCGC00090836-04, NCGC00090836-05, NCGC00090836-06, NCGC00094593-01, NCGC00094593-02, NCGC00094593-03, NCGC00260712-01, AJ-49795, AN-12213, CC-24218, CPD000427366, L996, SAM002589938, SC-04582, SMR000427366, 6-1'-Methyl,5'-imidazolyl mercaptopurine, SBI-0050016.P003, AB0014998, AB2000247, 6-(1-Methyl-4-nitromidazol-5-ylthio)purine, AB00443544, EU-0100027, FT-0083532, FT-0602904, ST24045004, 6-(1-Methyl-4-nitroimidazol-5-ylthio)purine, Azathioprine, meets USP testing specifications, 1767-EP0930075A1, 1767-EP2272822A1, 1767-EP2272825A2, 1767-EP2272827A1, 1767-EP2272832A1, 1767-EP2275420A1, 1767-EP2277865A1, 1767-EP2277876A1, 1767-EP2281815A1, 1767-EP2292227A2, 1767-EP2292614A1, 1767-EP2295409A1, 1767-EP2295412A1, 1767-EP2295413A1, 1767-EP2295426A1, 1767-EP2295427A1, 1767-EP2298743A1, 1767-EP2301933A1, 1767-EP2311827A1, 1767-EP2311837A1, 1767-EP2314590A1, 1767-EP2316834A1, 1767-EP2371811A2, C06837, D00238, AB00443544-03, AB00443544-11, AB00443544_12, AB00443544_13, Azasan;Imuran;Azamun;BW-57-322;NSC-39084, 055A974, 446A866, AG-670/36150031, AI-981/34845012, C-17433, SR-01000762955, 6-(1-Methyl-4-nitro-5-imidazolythio)-9H-pur-ine, 6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine, SR-01000075537-1, SR-01000075537-4, SR-01000762955-2, BRD-K32821942-001-05-6, BRD-K32821942-001-10-6, BRD-K60324116-001-01-5, WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW, Z57063156, 6-(3-methyl-5-nitro-imidazol-4-yl)sulfanyl-7H-purine, 6-(3-methyl-5-nitro-imidazol-4-yl)sulfanyl-9H-purine, 6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-9H-purine, 9H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-, Azathioprine, European Pharmacopoeia (EP) Reference Standard, 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-1H-purine #, Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine, Azathioprine, United States Pharmacopeia (USP) Reference Standard, Azathioprine, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 1281

InChIKey: LMFKRLGHEKVMNT-UJDVCPFMSA-N
SMILES: C[C@H]([C@@](C(C)C)(C(=O)OCC1=CCN2[C@H]1[C@H](CC2)O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 906426
synonyms found at PubChem are:
HELIOTRINE, 303-33-3, 7S-Heliotrine, (+)-Heliotrine, Heliotron, UNII-ZYB88Y4FUZ, CCRIS 9196, ZYB88Y4FUZ, CHEBI:5643, BRN 0292841, Butanoic acid, 2-hydroxy-2-((1R)-1-methoxyethyl)-3-methyl-, ((1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S)-, Butanoic acid, 2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methyl-, [(1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S)-, AI3-51769, 9-Heliotrylheliotridine, AC1LILA5, CHEMBL2165593, DTXSID3075381, LMFKRLGHEKVMNT-UJDVCPFMSA-N, MolPort-002-525-685, ZINC488161, Butanoic acid, 2-hydroxy-2-(1-methoxyethyl)-3-methyl-, (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1S-(1 alpha,7(2R*,3S*),7a alpha))-, AKOS030495261, MCULE-1156496490, C10324, J-017913, [(7S,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methylbutanoate, [(7S,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S,3R)-2-hydroxy-2-isopropyl-3-methoxy-butanoate

ID: 1282

InChIKey: LMILVXQXGKTFSZ-UHFFFAOYSA-N
SMILES: CC1=CCC(C2C1CC(=O)C(=C2)C)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3989419
synonyms found at PubChem are:
MUUROLLADIE-3-ONE, KBio2_001847, Spectrum_001367, SpecPlus_000371, AC1N1ZFA, Spectrum2_001784, Spectrum3_001336, Spectrum4_001735, Spectrum5_000530, BSPBio_003091, KBioGR_002150, KBioSS_001847, SPECTRUM307056, DivK1c_006467, SPBio_001707, CHEMBL1570340, KBio1_001411, KBio2_004415, KBio2_006983, KBio3_002311, CHEBI:110182, CCG-38433, SDCCGMLS-0066913.P001, NCGC00095613-01, NCGC00095613-02, SR-05000002458, SR-05000002458-1, BRD-A75954196-001-03-3, 3,8-dimethyl-5-propan-2-yl-4a,5,6,8a-tetrahydro-1H-naphthalen-2-one

ID: 1283

InChIKey: LMJSLTNSBFUCMU-UHFFFAOYSA-N
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5560
synonyms found at PubChem are:
trichlormethiazide, Trichloromethiazide, 133-67-5, Naqua, Trichlormetazid, Metahydrin, Achletin, Diurese, Trichlormethiazid, Diu-Hydrin, Chlopolidine, Hydrotrichlorothiazide, Aponorin, Cretonin, Diurazida, Diuroral, Fluitran, Gangesol, Intromene, Isestran, Schebitran, Triflumen, Esmarin, Flurese, Flutra, Nakva, Triclordiuride, Anistadin, Carvacron, Kubacron, Tachionin, Tolcasone, Trichlorex, Eurinol, Triclormetiazide, Trichloromethiadiazide, Metatensin, Trichlormas, Trichlordiuride, Triclormetiazida, Ciba 7057-Su, Salurin (wadel), Trichlormethiazidum, Flurese (VAN), Aquazide, Naquasone, Triclormetiazide [DCIT], Triclormetiazide [Italian], 3-Dichloromethylhydrochlorothiazide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide, Trichlormethiazidum [INN-Latin], NSC 61560, Trichlormethiazide [INN:JAN], Trichlormethiazide W/ Reserpine, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Naqua (TN), Triclormetiazida [INN-Spanish], trichloromethiazide, 6, HSDB 3406, 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, EINECS 205-118-8, BRN 0629145, 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3-(dichloromethyl)3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, MLS000028705, CHEBI:9683, 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide, 6-Chloro-3-dichloromethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide, SMR000058712, DSSTox_CID_3699, 3-(Dichloromethyl)-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-3-[dichloromethyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, 6-Chloro-3-dichloromethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide, DSSTox_RID_77154, DSSTox_GSID_23699, (+-)-6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, Q-201860, 6-Chloro-3-(dichloromethyl)3,4-dihydro-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide, (+-)-, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-,1,1-dioxide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, SR-01000000284, Triflumen (TN), NCGC00016398-01, Achletin (TN), Trichlormethiazide [USP:INN:JAN], 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, CAS-133-67-5, Diu-Hydrin (TN), Prestwick_1020, Spectrum_000520, AC1L1KMB, Opera_ID_1588, Prestwick0_000825, Prestwick1_000825, Prestwick2_000825, Prestwick3_000825, Spectrum2_000948, Spectrum3_001373, Spectrum4_000367, Spectrum5_001074, D0Y2IZ, AC1Q6TQ0, CHEMBL1054, NCIOpen2_007750, Trichlormethiazide, >=98%, SCHEMBL25492, BSPBio_000749, BSPBio_002926, KBioGR_000833, KBioSS_001000, Trichlormethiazide (Achletin), Achletin;Diu-Hydrin;Triflumen, MLS001076545, DivK1c_000366, SPECTRUM1500590, Triclormetiazida[INN-Spanish], SPBio_000916, SPBio_002670, BPBio1_000825, GTPL7314, DTXSID7023699, BDBM26998, CTK8B3334, HMS501C08, KBio1_000366, KBio2_001000, KBio2_003568, KBio2_006136, KBio3_002146, Jones Brand of Trichloromethiazide, LMJSLTNSBFUCMU-UHFFFAOYSA-N, MolPort-003-666-298, NINDS_000366, HMS1570F11, HMS1921G13, HMS2090G08, HMS2092O19, HMS2097F11, HMS2235K21, HMS3371B09, HMS3655I17, HMS3714F11, Pharmakon1600-01500590, HY-B0235, NSC61560, Schering Brand of Trichlormethiazide, Tox21_110421, 2764AH, ANW-42313, NSC-61560, NSC757368, s1667, Trichlormethiazide (JP15/USP/INN), Trichlormethiazide (JP17/USP/INN), AKOS024374993, Tox21_110421_1, API0008988, CCG-212834, CS-2203, DB01021, MCULE-5170594512, NSC-757368, IDI1_000366, NCGC00018302-02, NCGC00018302-03, NCGC00018302-04, NCGC00018302-07, NCGC00018302-08, NCGC00089756-02, NCGC00089756-03, AN-43719, LS-40435, SC-80012, SBI-0051544.P002, AB2000205, TR-004572, WLN: T66 BSWM EM DHJ DYGG HG ISZW, AB00052117, FT-0746865, ST51015129, C07767, D00658, 54260-EP2269989A1, 54260-EP2272832A1, 54260-EP2308562A2, 66946-EP2295406A1, 66946-EP2298772A1, 66946-EP2298776A1, 66946-EP2308839A1, AB00052117-15, AB00052117_16, AB00052117_17, American Urologicals Brand of Trichloromethiazide, C-44332, SR-01000000284-2, SR-01000000284-4, BRD-A28940325-001-05-9, BRD-A28940325-001-15-8, I14-107329, 6-Chloro-3-(dichloromethyl)3,2,4-benzothiadiazine-1,1-dioxide, Trichlormethiazide, United States Pharmacopeia (USP) Reference Standard, 2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3-(dichloromethyl)-3,4-dihydr, 3-(dichloromethyl)-6-chloro-1,1-dioxo-2H,3H,4H-benzo[e]1,2,4-thiadiazine-7-sul fonamide, 3-(Dichloromethyl)-6-chloro-7-sulfamoyl-3,2,4-benzothiadiazine 1,1-dioxide, 3-(Dichloromethyl)-6-chloro-7-sulfamoyl-3,2,4-benzothiadiazine-1,1-dioxide, 3-(Dichloromethyl)-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 3-dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1, 6-Chloro-3-(dichloromethyl)-3,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-thiadiazine-7-sulfonamide 1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide, 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide, 96782-89-7

ID: 1284

InChIKey: LMPZHLXYBWGGNT-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)NC4=CC=CC=C4C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 128355
synonyms found at PubChem are:
SR 2640, SR-2640, 105350-26-3, CHEMBL18132, SR2640, Benzoic acid, 2-[[3-(2-quinolinylmethoxy)phenyl]amino]-, QMPB, Benzoic acid, 2-((3-(2-quinolinylmethoxy)phenyl)amino)-, SR-01000076219, 2-[[3-(2-QuinolinylMethoxy)phenyl]aMino]benzoicacidhydrochloride, Tocris-1804, Lopac-S-7690, D00MHP, AC1L2TN9, 2-(3-(2-Quinolylmethoxy)phenylamino)benzoic acid, Lopac0_001079, MLS002153402, cid_128355, GTPL3329, SCHEMBL9119607, CTK8F0698, CHEBI:104023, HMS2236C03, HMS3263G20, HMS3373N15, ZINC596951, Tox21_501079, BDBM50006798, AKOS030239522, CCG-205156, LP01079, NCGC00015965-01, NCGC00015965-02, NCGC00015965-03, NCGC00015965-04, NCGC00015965-05, NCGC00015965-06, NCGC00025299-01, NCGC00025299-02, NCGC00025299-03, NCGC00261764-01, AJ-23638, SMR001230780, RT-015775, SR 2640, >=99% (HPLC), solid, EU-0101079, S 7690, 2-[3-(quinolin-2-ylmethoxy)anilino]benzoic acid, SR-01000076219-2, 2-(3-(quinolin-2-ylmethoxy)phenylamino)benzoic acid, BRD-K62562723-003-01-9, 2-[[3-(2-Quinolinylmethoxy)phenyl]amino]-benzoic acid, 2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic acid, 2-{[3-(quinolin-2-ylmethoxy)phenyl]amino}benzoic acid, 2-[[3-(2-Quinolinylmethoxy)phenyl]amino]-benzoic acid; QMPB, 2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic acid(SR2640)

ID: 1285

InChIKey: LNEPOXFFQSENCJ-UHFFFAOYSA-N
SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3559
synonyms found at PubChem are:
haloperidol, 52-86-8, Haldol, Aloperidin, Serenace, Aloperidol, Brotopon, Eukystol, Einalon S, Aloperidolo, Galoperidol, Halojust, Halopoidol, Serenase, Serenelfi, Ulcolind, Uliolind, Vesalium, Halopal, Linton, Mixidol, Pernox, Sernas, Sernel, Dozic, Aldo, Lealgin compositum, Keselan, Peluces, Bioperidolo, Haloperidolum, Sigaperidol, Haldol Solutab, McN-JR-1625, Aloperidon, Fortunan, Halosten, Aloperidolo [DCIT], Halidol, Halopidol, Pekuces, Halol, Aloperidolo [Italian], Haloperidolum [INN-Latin], 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one, Haloperido, Peridol, Dozix, R 1625, R-1625, Apo-Haloperidol, Pms Haloperidol, Novo-Peridol, Haldol La, C21H23ClFNO2, 1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, NSC 170973, UNII-J6292F8L3D, Haldol (TN), CCRIS 1630, Haloperidol (Haldol), 4'-Fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone, 4'-Fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone, HSDB 3093, Haloperidol lactate, Haloperidol [USAN:INN:BAN:JAN], CHEMBL54, EINECS 200-155-6, NSC 615296, 4-(4-Hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone, BRN 0331267, 1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-, 4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone, 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone, MLS000028450, CHEBI:5613, LNEPOXFFQSENCJ-UHFFFAOYSA-N, 4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone, 4-[4-(p-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone, J6292F8L3D, Butyrophenone, 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-, Haloperidol Intensol, 1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-, 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one, IN1474, NSC170973, NSC615296, CAS-52-86-8, NCGC00015500-10, SMR000058303, 4'-Fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone, 4-[4-(4-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone, gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone, 4-(4-(para-Chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone, Butyrophenone, 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-, gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one, H 1512, DSSTox_CID_14150, DSSTox_RID_79117, DSSTox_GSID_34150, W-105791, haloperin, Butyrophenone, 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluoro-, gamma-(4-(p-Chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one, 177716-59-5, 61788-97-4, SR-01000003076, Haloperidol (JP15/USP), Duraperidol, Resin epoxy, 4'-Fluoro-4-[4-hydroxy-4-(4'-chlorophenyl)piperidino]butyrophenone, gamma-[4-(p-chlorophenyl)-4-hydroxypiperidino]-p-fluorobutyrophenone, 4-[4-(para-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone, Picroside-III, Haloperidol, 1, Aloperidin (TN), Bioperidolo (TN), Duraperidol (TN), Sigaperidol (TN), Brotopon (TN), Eukystol (TN), Halosten (TN), Serenace (TN), Serenase (TN), Haloperidol, powder, Prestwick_250, Keselan (TN), Peluces (TN), Phenolic epoxy resin, Linton (TN), Einalon S (TN), Dozic (TN), Haloperidol [USAN:USP:INN:BAN:JAN], MDMO-PPV, Spectrum_000861, Tocris-0931, Opera_ID_446, 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl), Prestwick0_000115, Prestwick1_000115, Prestwick2_000115, Prestwick3_000115, Spectrum2_001268, Spectrum3_000448, Spectrum4_000570, Spectrum5_000788, Lopac-H-1512, Biomol-NT_000035, D0D1AL, GTPL86, Probes1_000255, Probes2_000296, AC1L1G7K, SCHEMBL8264, Lopac0_000583, Oprea1_509923, BSPBio_000130, BSPBio_002096, KBioGR_000980, KBioGR_002390, KBioSS_001341, KBioSS_002395, 5-21-02-00377 (Beilstein Handbook Reference), MLS001146904, BIDD:GT0128, DivK1c_000654, SPECTRUM1500325, SPBio_001236, SPBio_002069, McM-JR-1625, AC1Q77Z0, BPBio1_000144, BPBio1_001231, Haloperidol (JP15/USP/INN), Haloperidol (JP17/USP/INN), DTXSID4034150, BDBM21398, HMS502A16, KBio1_000654, KBio2_001341, KBio2_002390, KBio2_003909, KBio2_004958, KBio2_006477, KBio2_007526, KBio3_001316, KBio3_002869, LNEPOXFFQSENCJ-UHFFFAOYSA-, AOB5645, cMAP_000037, MolPort-000-883-311, NINDS_000654, AC250, HMS1568G12, HMS1920D03, HMS2089M15, HMS2091J09, HMS2095G12, HMS2234P08, HMS3261F08, HMS3370H11, HMS3657I13, HMS3712G12, Pharmakon1600-01500325, ZINC537822, Haloperidol 1.0 mg/ml in Methanol, Tox21_110162, Tox21_300475, Tox21_500583, A0H334, BG0211, CCG-36042, CCG-39111, MFCD00051423, NSC757054, STL417208, AKOS000280660, Tox21_110162_1, API0002885, CS-1971, DB00502, LP00583, MCULE-3693790133, NSC-170973, NSC-615296, NSC-757054, IDI1_000654, MRF-0000027, QTL1_000042, WLN: T6NTJ A3VR DF& DQ DR DG, NCGC00015500-01, NCGC00015500-02, NCGC00015500-03, NCGC00015500-04, NCGC00015500-05, NCGC00015500-06, NCGC00015500-07, NCGC00015500-08, NCGC00015500-09, NCGC00015500-11, NCGC00015500-12, NCGC00015500-13, NCGC00015500-14, NCGC00015500-15, NCGC00015500-16, NCGC00015500-17, NCGC00015500-19, NCGC00016234-01, NCGC00023875-02, NCGC00023875-04, NCGC00023875-05, NCGC00023875-06, NCGC00023875-07, NCGC00023875-08, NCGC00023875-09, NCGC00254503-01, NCGC00261268-01, AC-19691, AN-41634, CC-16450, HY-14538, KB-79571, LS-48311, SC-81035, ACM1189986591, SBI-0050565.P004, AB2000375, SC 170973, TR-018722, AB00052008, EU-0100583, FT-0669100, FT-0697842, N1910, S1920, ST50319916, W0039, 4763-EP2269989A1, 4763-EP2269990A1, 4763-EP2272537A2, 4763-EP2272972A1, 4763-EP2272973A1, 4763-EP2275420A1, 4763-EP2277872A1, 4763-EP2277876A1, 4763-EP2292614A1, 4763-EP2295061A1, 4763-EP2295412A1, 4763-EP2295413A1, 4763-EP2295439A1, 4763-EP2298731A1, 4763-EP2298776A1, 4763-EP2305260A1, 4763-EP2308867A2, 4763-EP2308870A2, 4763-EP2311801A1, 4763-EP2311803A1, 4763-EP2311824A1, 4763-EP2311837A1, 4763-EP2316834A1, C01814, D00136, VU0239704-10, AB00052008-21, AB00052008-22, AB00052008_23, AB00052008_24, C-35402, L000288, SR-01000003076-2, SR-01000003076-8, BRD-K67783091-001-04-8, BRD-K67783091-001-05-5, BRD-K67783091-003-03-6, I14-13404, I14-14165, SR-01000003076-11, Haloperidol, European Pharmacopoeia (EP) Reference Standard, Poly[2-methoxy-5-(3,7-dimethyoctyoxyl)-1,4-phenylenevinylene], .gamma.-[4-(p-Chlorphenyl)-4-hydroxpiperidino]-p-fluorbutyrophenone, Haloperidol, United States Pharmacopeia (USP) Reference Standard, .gamma.-(4-(p-Chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone, 4-[4-(4-chlorophenyl)-4-hydroxypiperidyl]-1-(4-fluorophenyl)butan-1-one, Haloperidol, Pharmaceutical Secondary Standard; Certified Reference Material, 4-[4-(4-Chlorophenyl)-4-hydroxy- 1-piperidinyl]-1-(4-fluorophenyl)- 1-butanone, 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl) -1-butanone, Haloperidol for peak identification, European Pharmacopoeia (EP) Reference Standard, Haloperidol for system suitability, European Pharmacopoeia (EP) Reference Standard, InChI=1/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

ID: 1286

InChIKey: LNPDTQAFDNKSHK-UHFFFAOYSA-N
SMILES: CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 119607
synonyms found at PubChem are:
Valdecoxib, 181695-72-7, Bextra, 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide, SC-65872, Valdyn, 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide, Kudeq, Valdecoxib [USAN], SC 65872, Benzenesulfonamide, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide, Valecoxib, YM-974, HSDB 7302, UNII-2919279Q3W, Valdecoxib (USAN/INN), CHEMBL865, p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide, CHEBI:63634, LNPDTQAFDNKSHK-UHFFFAOYSA-N, 4-(5-methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide, 4-(5-methyl-3-phenyl-isoxazol-4-yl)benzenesulfonamide, COX, ND-0214, NCGC00095129-01, 2919279Q3W, DSSTox_CID_24226, DSSTox_RID_80128, DSSTox_GSID_44226, 4-(Methyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide, C16H14N2O3S, 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide, Bextra(Valdecoxib), SMR000466327, CAS-181695-72-7, 4-[5-methyl-3-phenylisoxazol-4-yl]benzenesulfonamide, valdecoxibum, Vatdecoxib, Valdecoxib [USAN:INN:BAN], Valdecoxib/, Spectrum_001747, 2aw1, Spectrum2_000508, Spectrum3_001001, Spectrum4_001129, Spectrum5_001476, Pfizer brand of valdecoxib, D0L6DA, SCHEMBL3356, BSPBio_002721, KBioGR_001617, KBioSS_002227, MLS000759433, MLS001165699, MLS001195631, MLS001424105, SPECTRUM1504302, SPBio_000435, AC1L3P42, cid_119607, GTPL2894, ZINC6694, DTXSID6044226, Valdecoxib, >=98% (HPLC), BDBM13063, CTK8E7482, KBio2_002227, KBio2_004795, KBio2_007363, KBio3_001941, KS-00000XKX, EX-A241, MolPort-000-883-874, HMS1922J21, HMS2051P07, HMS2232P23, HMS3372D12, HMS3393P07, HMS3652I04, HMS3715L18, Pharmakon1600-01504302, BCP02419, Tox21_111438, ABP000351, AC-120, CCG-39589, MFCD00950568, NSC759846, s4049, AKOS000280920, Tox21_111438_1, API0004561, CS-1674, DB00580, NC00184, NSC-759846, RL02316, MRF-0000216, NCGC00095129-02, NCGC00095129-03, NCGC00095129-06, Valdecoxib, analytical reference material, AJ-08285, AN-16123, BC209355, CC-35561, CPD000466327, HY-15762, KB-62216, SAM001246603, SC-19235, ZB000648, ACM1189428236, AB0125618, AX8016203, LS-173713, RT-016210, UNM-0000305814, 4CH-003246, FT-0631199, ST24042991, C21552, D02709, AB00639996-08, AB00639996_10, 695V727, A812629, C-19398, SR-01000759421, J-011613, J-513600, SR-01000759421-4, 4-[5-methyl-3-phenylisoxazol-4-yl]benzensulfonamide, BRD-K12994359-001-02-8, BRD-K12994359-001-14-3, I14-44902, 4-(5-Methyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide, Benzenesulfonamide, 4-(5-methyl-3-phenyl-4-isoxazolyl)-(9CI), Benzenesulfonamide, 4-(5-methyl-3-phenyl-4-isoxazolyl)- (9CI), InChI=1/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20, VLX

ID: 1287

InChIKey: LNQCUTNLHUQZLR-OZJWLQQPSA-N
SMILES: COC1=CC(=CC(=C1OC)O)C2=COC3=CC(=C(C(=C3C2=O)O)OC)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281777
synonyms found at PubChem are:
Iridin, 491-74-7, UNII-6NTS007OHQ, Spectrum_000619, SpecPlus_000143, Spectrum2_000198, Spectrum3_000192, 6NTS007OHQ, CHEBI:5963, Lridin, C24H26O13, Spectrum4_001510, Spectrum5_000279, AC1NQZ28, BSPBio_001743, KBioGR_002179, KBioSS_001099, SPECTRUM200793, DivK1c_006239, SCHEMBL243567, SPBio_000155, CHEMBL487014, KBio1_001183, KBio2_001099, KBio2_003667, KBio2_006235, KBio3_001243, KS-00000TYO, DTXSID80197689, MolPort-003-665-855, ZINC3978463, irigenin 7-O-beta-D-glucopyranoside, 9568AF, CCG-38404, AKOS030632867, SDCCGMLS-0066463.P001, NCGC00179041-01, N1932, C10465, SR-05000002736, SR-05000002736-1, BRD-K22550622-001-02-7, BRD-K22550622-001-03-5, 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-, 5-hydroxy-3-(3-hydroxy-4,5-dimethoxy-phenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one, 5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranoside, 5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one

ID: 1288

InChIKey: LNSKUBQTAKEJOP-UHFFFAOYSA-L
SMILES: CCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(COP(=O)([O-])OCC(COC(=O)CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)OC(=O)CCCCCCCCCCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 98042585
synonyms found at PubChem are:
CARDIOLIPIN SODIUM

ID: 1289

InChIKey: LNTHITQWFMADLM-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 370
synonyms found at PubChem are:
Gallic acid, 3,4,5-Trihydroxybenzoic acid, 149-91-7, gallate, Benzoic acid, 3,4,5-trihydroxy-, Gallic acid, tech., GALOP, Pyrogallol-5-carboxylic acid, Kyselina gallova, HSDB 2117, 3,4,5-Trihydroxybenzoate, CCRIS 5523, Kyselina gallova [Czech], Gallic acid polymer, UNII-632XD903SP, Gallicum acidum, GALLICACID, CHEBI:30778, AI3-16412, Kyselina 3,4,5-trihydroxybenzoova, EINECS 205-749-9, NSC 20103, NSC 674319, BRN 2050274, GALLIC ACID ANHYDROUS, Kyselina 3,4,5-trihydroxybenzoova [Czech], CHEMBL288114, LNTHITQWFMADLM-UHFFFAOYSA-N, 632XD903SP, NSC20103, NSC674319, NCGC00091125-01, DSSTox_CID_650, DSSTox_RID_75711, DSSTox_GSID_20650, CAS-149-91-7, Gallic acid [NF], MFCD00002510, SR-05000001537, Gallic acid tech., Gallic Acid, F, Gallic acid, tech, GDE, (?)-Gallic acid, Gallic Acid Hydrate, Spectrum_000342, ACMC-20aku5, SpecPlus_000307, 5-Trihydroxybenzoic acid, Spectrum2_000399, Spectrum3_000254, Spectrum4_001544, Spectrum5_000108, bmse000389, D0Y3TZ, 3,5-Trihydroxybenzoic acid, WLN: QVR CQ DQ EQ, 3,4,5-trihydroxy-Benzoate, Oprea1_087792, SCHEMBL15012, BSPBio_001668, KBioGR_002008, KBioSS_000822, SPECTRUM210369, 3-10-00-02070 (Beilstein Handbook Reference), KSC175M1R, ARONIS23903, BIDD:ER0374, DivK1c_006403, SPBio_000617, 3,4,5-Trihydroxybenzoate, X, Benzoic acid,4,5-trihydroxy-, AC1Q732X, AC1Q732Y, GTPL5549, ZINC1504, Jsp002851, 3,4,5-trihydroxy-Benzoic acid, 3,4,5-Trihydroxybenzoic acid;, 5-Carboxybenzene-1,2,3-triol, DTXSID0020650, CTK0H5618, KBio1_001347, KBio2_000822, KBio2_003390, KBio2_005958, KBio3_001168, KS-00000IWM, CPD-183, Gallic acid, puriss., 98.0%, MolPort-000-881-260, HMS1923K07, HMS2091A07, Pharmakon1600-00210369, AC1L1934, BCP18127, HY-N0523, NSC36997, Tox21_111089, Tox21_202515, BBL009937, BDBM50085536, CCG-38670, CG0029, EBD679760, LS-870, NSC-20103, NSC-36997, NSC755825, s4603, SBB008781, STK298718, AKOS000119625, Tox21_111089_1, AC-1206, CS-8191, MCULE-1552954312, NSC-674319, NSC-755825, PS-8710, RP23206, RTR-020762, SDCCGMLS-0066503.P001, NCGC00091125-02, NCGC00091125-03, NCGC00091125-04, NCGC00091125-05, NCGC00091125-07, NCGC00260064-01, 4CN-0954, AJ-08037, AN-15162, BC200279, gallic acid for microelectronic industrial, SC-46383, ST083487, SBI-0052184.P002, AB1002218, Gallic acid, 97.5-102.5% (titration), ST2404570, TR-020762, FT-0626592, G0011, N1830, T7419, KS-00004784, C01424, 3,4,5-trihydroxybenzoic acid (ACD/Name 4.0), AB00052697_03, I14-9302, Q-201146, SR-05000001537-1, SR-05000001537-2, SR-05000001537-3, BRD-K77345217-001-01-9, Gallic acid (Monohydrate or Anhydrous) (3,4,5-Trih, F1908-0156, Gallic acid, certified reference material, TraceCERT(R), Z966690556, 78563C7D-0E2D-4766-A8EA-670A03C78FCF, InChI=1/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12, 138-57-8

ID: 1290

InChIKey: LNVFIVSNGPLFPU-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC4=CC=CC=C43

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 281852
synonyms found at PubChem are:
4'-methoxy-5,6-benzoflavone, 3-(4-methoxyphenyl)benzo[f]chromen-1-one, CHEMBL2420093, 125240-02-0, 3-(4-METHOXYPHENYL)-1H-BENZO[F]CHROMEN-1-ONE, NSC134766, AC1L5V7M, 4'-Methoxy-ss-naphthoflavone, SCHEMBL7116289, ZINC38942, 4'-Methoxy-.beta.-naphthoflavone, LNVFIVSNGPLFPU-UHFFFAOYSA-N, Methoxy 4'-.beta.-naphthoflavone, BDBM50439842, CCG-23501, AKOS001683485, MCULE-3009064283, NSC 134766, NSC-134766, ST055368, EU-0082240, FT-0740563, AB01316754-02, C-57492, 1H-Naphtho[2,1-b]pyran-1-one,3-(4-methoxyphenyl)-, I14-38975, 1H-Naphtho[2,1-b]pyran-1-one, 3-(4-methoxyphenyl)-

ID: 1291

InChIKey: LOBCDGHHHHGHFA-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4241
synonyms found at PubChem are:
monastrol, 329689-23-8, 254753-54-3, ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE, 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester, CHEBI:75382, IN1223, ( inverted exclamation markA)-Monastrol, SR-01000357662, AC1MGLGQ, D0ZK2G, Probes1_000001, Probes1_000042, Probes1_000312, Probes2_000257, Probes2_000376, Lopac0_000821, Oprea1_487786, BSPBio_001273, CBDivE_015834, KBioGR_000613, KBioSS_000613, MLS006011746, SCHEMBL3168349, BCBcMAP01_000162, CTK8E8078, KBio2_000613, KBio2_003181, KBio2_005749, KBio3_001085, KBio3_001086, AOB2016, DTXSID10388124, LOBCDGHHHHGHFA-UHFFFAOYSA-N, MolPort-000-207-634, MolPort-000-676-468, BDBM175356, Bio1_000459, Bio1_000948, Bio1_001437, Bio2_000467, Bio2_000947, HMS1362O15, HMS1792O15, HMS1990O15, HMS3267N03, HMS3403O15, BCP06757, BCP19385, GR-322, MFCD00813077, NSC716782, s8439, STK386781, ZINC00297106, Monastrol, >=98% (HPLC), solid, AKOS000295413, AKOS002264887, AKOS016068396, AKOS016315550, API0000665, CS-6183, HY-101071A, MCULE-4594335775, NSC-716782, IDI1_002222, SMP1_000197, TRA-0189278, UPCMLD0ENAT5762435:001, NCGC00025103-01, NCGC00025103-02, NCGC00025103-03, NCGC00025103-04, BAS 00667373, NCI60_040353, SMR004703468, ST075209, KB-296833, RT-013930, FT-0628969, FT-0631206, M 8515, S-7829, J-016007, SR-01000357662-1, SR-01000357662-2, BRD-A78377521-001-02-2, BRD-A78377521-001-03-0, F3284-6466, 6-Methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-3,4-dihydro-1H-pyrimidine-5-carboxylate, ethyl 6-(3-hydroxyphenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate, Ethyl 6-(3-hydroxyphenyl)-4-methyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-(3-hydroxyphenyl)-4-methyl-2-thioxo-1,3,6-trihydropyrimidine-5-carboxy late, ethyl 6-methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, 1,2,3,4-Tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid, ethyl ester, Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (11)

ID: 1292

InChIKey: LOGJQOUIVKBFGH-YBEGLDIGSA-N
SMILES: CN(C)S(=O)(=O)C1=CC\2=C(C=C1)NC(=O)/C2=C\C3=CC4=C(N3)CCCC4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5312137
synonyms found at PubChem are:
su6656, SU 6656, 330161-87-0, SU-6656, InSolution™ SU6656, CHEMBL605003, (3z)-N,N-Dimethyl-2-Oxo-3-(4,5,6,7-Tetrahydro-1h-Indol-2-Ylmethylidene)-2,3-Dihydro-1h-Indole-5-Sulfonamide, (3Z)-N,N-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indole-5-sulfonamide, SR-01000076237, 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide, AC1NSM2X, Lopac-S-9692, D0CE3R, Lopac0_000979, MLS002153475, GTPL6044, EX-A584, LOGJQOUIVKBFGH-YBEGLDIGSA-N, MolPort-003-959-609, HMS2232C04, HMS3229I04, HMS3263C19, HMS3648O08, HY-B0789, ZINC3875028, Tox21_500979, 4071AH, BDBM50307127, HSCI1_000124, MFCD10565928, s7774, AKOS015994571, CCG-205059, CS-3943, DB08039, ES-0024, LP00979, NCGC00015981-01, NCGC00015981-02, NCGC00015981-03, NCGC00015981-04, NCGC00015981-05, NCGC00015981-06, NCGC00094279-01, NCGC00094279-02, NCGC00261664-01, BC600759, SMR001230828, RT-015805, B5839, EU-0100979, SU 6656, >=98% (HPLC), S 9692, SR-01000076237-1, SR-01000076237-6, BRD-K97354755-001-01-5, N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide, (Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide, 2-Oxo-3-[1-(4,5,6,7-tetrahydro-1H-indol-2-yl)-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide

ID: 1293

InChIKey: LOIYMIARKYCTBW-OWOJBTEDSA-N
SMILES: C1=C(NC=N1)/C=C/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 736715
synonyms found at PubChem are:
urocanic acid, 4-imidazoleacrylic acid, trans-Urocanic acid, 104-98-3, urocanate, Urocaninic acid, imidazoleacrylic acid, 5-Imidazoleacrylic acid, 3465-72-3, (2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID, Imidazole-4-acrylic acid, 3-Imidazol-4-ylacrylic acid, 3-(1H-Imidazol-4-yl)-2-propenoic acid, UNII-G8D26XJJ3B, (E)-3-(1H-Imidazol-4-yl)-2-propenoic acid, (2E)-3-(1H-imidazol-4-yl)prop-2-enoic acid, 2-Propenoic acid, 3-(1H-imidazol-4-yl)-, NSC 66357, UROCANIC ACID, CIS, G8D26XJJ3B, (e)-3-(1h-imidazol-4-yl)acrylic acid, (E)-3-(1H-imidazol-5-yl)acrylic acid, 3-(4-Imidazolyl)acrylic acid, MLS000069482, CHEBI:30817, LOIYMIARKYCTBW-OWOJBTEDSA-N, 2-Propenoic acid, 3-(1H-imidazol-4-yl)-, (2E)-, 3-(1H-imidazol-4-yl)prop-2-enoic acid, SMR000059098, Imidazole-4-propene-2-enoic acid [Urocanic acid], 4-IMIDAZOLE ACRYLIC ACID DIHYDRATE, CCRIS 3414, EINECS 203-258-4, (E)-Urocanic acid, BRN 0081405, (2E)-3-imidazol-4-ylprop-2-enoic acid, (E)-3-(imidazol-4-yl)propenoate, ProtoCure, 5-Imidazoleacrylate, zlchem 24, Imidazole-4-acrylate, imidazolylpropenoicacid, PubChem9875, (E)-3-(1H-Imidazol-5-yl)-2-propenoic acid, (Z)-3-(3H-imidazol-4-yl)prop-2-enoic Acid, AC1LEIQR, Opera_ID_26, 3-(4-Imidazolyl)acrylate, bmse000279, D04CQV, AC1Q5T9G, AC1Q71IX, DSSTox_CID_21148, DSSTox_RID_79635, DSSTox_GSID_41148, Lopac0_001255, SCHEMBL15417, trans-4-imidazoleacrylic acid, MLS001148240, 2-Propenoic acid, 3-(1H-imidazol-4-yl)-, (E)-, 4-Imidazoleacrylic acid, 99%, AC1Q71Y1, Jsp000483, 3-(1H-Imidazol-4-yl)acrylate, CHEMBL1236602, DTXSID5041148, CHEBI:27248, ZLB0011, MolPort-001-763-955, MolPort-006-833-341, MolPort-009-660-446, E-3-(4-imidazolyl)propenoic acid, HMS2234N08, HMS3263L12, ACT02032, ALBB-025618, NSC66357, Tox21_202978, Tox21_501255, BBL027507, MFCD01593677, NSC-66357, NSC407934, SBB006702, STK735136, ZINC34633903, (E)-3-(imidazol-4-yl)acrylic acid, 3-(3H-Imidazol-4-yl)-acrylic acid, 3-(1H-Imidazol-4-yl)-2-propenoate, AKOS001745677, AKOS005265082, AKOS022488522, (e)-3-(Imidazol-4-yl)propenoic acid, CCG-205329, DB01971, HS-0075, LP01255, NSC-407934, RP09780, RTR-032578, NCGC00094495-01, NCGC00094495-02, NCGC00094495-03, NCGC00260524-01, NCGC00261940-01, CAS-104-98-3, CJ-18538, LS-78025, SC-00208, ST085933, 3-(1H-Imidazol-5-yl)-2-Propenoic acid, 3-Azonia-1H-imidazole-5-acrylic acidanion, HY-113008, KB-176840, KB-180998, TR-032578, (2E)-3-(1H-Imidazole-4-yl)propenoic acid, CS-0059340, EU-0101255, I0002, R1116, (E)-3-(1H-imidazol-4-yl)prop-2-enoic acid, (E)-3-(1H-imidazol-5-yl)prop-2-enoic acid, 3-(1H-Imidazol-4-yl)-(E)-2-Propenoic acid, C00785, U 7500, (2E)-3-(1H-imidazol-5-yl)prop-2-enoic acid, (2E)-3-(3H-imidazol-4-yl)prop-2-enoic acid, SR-01000076189, I04-0134, SR-01000076189-1, W-108797, ProtoCure (emulsion, atopic dermatitis), Biocis Pharma, 23A7DA77-EC02-46B9-AA22-514C2B2A62E9, ProtoCure (emulsion, atopic dermatitis/psoriasis), Laurantis, Anti-inflammatory (topical emulsion, dermatological disease), BioCis, Cis-UCA (topical emulsion, atopic dermatitis/psoriasis), Laurantis, ProtoCure (emulsion, atopic dermatitis/psoriasis), Biocis Pharma, Cis-UCA (topical emulsion, atopic dermatitis/psoriasis), BioCis Pharma, Cis-urocanic acid (topical emulsion, atopic dermatitis/psoriasis), BioCis Pharma, 7699-36-7

ID: 1294

InChIKey: LPBCTXJGOILQDR-UHFFFAOYSA-N
SMILES: C1=CSC(=C1)C2=NN=C(N=N2)C3=CC=CS3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 12292738
synonyms found at PubChem are:
3,6-Di(2-thienyl)-1,2,4,5-tetrazine, SCHEMBL13977912, 3,6-di(thiophen-2-yl)-1,2,4,5-tetrazine, 59918-60-4

ID: 1295

InChIKey: LPEPZBJOKDYZAD-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3371
synonyms found at PubChem are:
flufenamic acid, 530-78-9, Fluphenamic acid, Nichisedan, Achless, Arlef, Flufacid, Fullsafe, Lanceat, Paraflu, Plostene, Tecramine, Parlef, Parlif, Surika, Flufenaminsaeure, Reumajust A, Acido flufenamico, Ristogen, Sastridex, Ansatin, Meralen, N-(3-Trifluoromethylphenyl)anthranilic acid, 2-((3-(Trifluoromethyl)phenyl)amino)benzoic acid, Fluore-200, 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid, ANT-1, Acide flufenamique, Acidum flufenamicum, TVX 916, INF 1837, 3'-Trifluoromethyldiphenylamine-2-carboxylic acid, CI 440, NSC-82699, Flufenaminsaeure [German], C.I. 440, CN-27,554, UNII-60GCX7Y6BH, Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, Acido flufenamico [Italian], NSC 219007, CCRIS 5266, 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid, C14H10F3NO2, Acide flufenamique [INN-French], Acido flufenamico [INN-Spanish], Acidum flufenamicum [INN-Latin], 2-[3-(Trifluoromethyl)anilino]benzoic acid, INF-1837, 2-((3-Trifluromethyl)phenyl)aminobenzoic acid, EINECS 208-494-1, N-(m-Trifluoromethylphenyl)-2-aminobenzoic acid, Flufenamic acid [USAN:INN:BAN:JAN], BRN 1996069, 60GCX7Y6BH, Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, CHEMBL23588, N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilic acid, MLS000028563, 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, CHEBI:42638, LPEPZBJOKDYZAD-UHFFFAOYSA-N, Saal-F, NCGC00016490-06, CAS-530-78-9, SMR000059027, N-(3-Trifluoromethylphenyl)-anthranilic acid, DSSTox_CID_3063, N-[3-(Trifluoromethyl)phenyl]anthranilic acid, WLN: QVR BMR CXFFF, DSSTox_RID_76859, DSSTox_GSID_23063, FFA, Anthranilic acid, N-(alpha,alpha,alpha-trifluoro-m-tolyl)-, FLF, 2-[(3-Trifluromethyl)phenyl]aminobenzoic acid, N-[(3-Trifluoromethyl)phenyl]anthranilic acid, N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid, N-[(m-Trifluoromethyl)phenyl]-2-aminobenzoic acid, N-[m-(Trifluoromethyl)phenyl]-2-aminobenzoic acid, SR-01000000241, Anthranilic acid,.alpha.,.alpha.-trifluoro-m-tolyl)-, N-(.alpha.,.alpha.-Trifluoro-m-tolyl)anthranilic acid, Prestwick_220, Arlef (TN), Spectrum_001257, 1bm7, Opera_ID_578, Prestwick0_000203, Prestwick1_000203, Prestwick2_000203, Prestwick3_000203, Spectrum2_000789, Spectrum3_001273, Spectrum4_000102, Spectrum5_000686, D0B2WJ, EC 208-494-1, AC1L1FS8, CBiol_001756, SCHEMBL17497, BSPBio_000185, BSPBio_001319, BSPBio_002866, CBDivE_012649, KBioGR_000039, KBioGR_000424, KBioGR_002267, KBioSS_000039, KBioSS_001737, KBioSS_002268, 3-14-00-00905 (Beilstein Handbook Reference), KSC911Q2R, MLS001148610, DivK1c_000581, SPECTRUM1501015, SPBio_000898, SPBio_002106, ACMC-209l43, AC1Q72G6, BPBio1_000205, GTPL2447, DTXSID7023063, BCBcMAP01_000039, BDBM17636, CTK8B1828, HMS501N03, KBio1_000581, KBio2_000039, KBio2_001737, KBio2_002267, KBio2_002607, KBio2_004305, KBio2_004835, KBio2_005175, KBio2_006873, KBio2_007403, KBio3_000077, KBio3_000078, KBio3_002366, KBio3_002747, ZINC86535, cMAP_000004, MolPort-000-421-382, NINDS_000581, Bio1_000042, Bio1_000531, Bio1_001020, Bio2_000039, Bio2_000519, Flufenamic acid (JAN/USAN/INN), HMS1361B21, HMS1568J07, HMS1791B21, HMS1921B21, HMS1989B21, HMS2089E07, HMS2092B09, HMS2095J07, HMS2232G24, HMS3371F01, HMS3402B21, HMS3652F06, HMS3712J07, Pharmakon1600-01501015, HY-B1221, KS-000015VF, NSC82699, Tox21_110452, Tox21_302111, ANW-31633, BBL001490, CCG-40167, HTS000643, NSC219007, NSC757823, s4268, SBB001140, STK985630, AKOS000265536, Tox21_110452_1, CS-4811, DB02266, KS-1143, MCULE-8606118307, NE10194, NSC-219007, NSC-757823, IDI1_000581, IDI1_033789, NCGC00016490-01, NCGC00016490-02, NCGC00016490-03, NCGC00016490-04, NCGC00016490-05, NCGC00016490-07, NCGC00016490-08, NCGC00016490-09, NCGC00016490-10, NCGC00016490-12, NCGC00023200-03, NCGC00023200-04, NCGC00023200-05, NCGC00023200-06, NCGC00023200-07, NCGC00255175-01, 2-(3-Trifluoromethylanilino)benzoic Acid, AJ-10755, AN-16724, BC207258, CN-27544, CN-27554, LS-20583, M456, SC-17641, ST026563, N-(3-Trifluoromethylphenyl)anthranilicAcid, SBI-0051633.P002, RT-000369, 2-[3-(trifluoromethyl)anilino]-benzoic acid, AB00052198, FT-0603454, ST24038963, UNM000001246003, 2-[3-(Trifluoromethyl)anilino]benzoic acid #, 2-(3-(trifluoromethyl)phenylamino)benzoic acid, 2-[(3-Trifluoromethylphenyl)amino]benzoic Acid, C13038, D01581, AB00052198-14, AB00052198_15, 530F789, SR-01000000241-2, SR-01000000241-3, W-105772, BRD-K44067360-001-06-3, BRD-K44067360-001-16-2, I14-19098, F0909-0007, Flufenamic acid, analytical standard, for drug analysis, N-(.alpha.,.alpha.,.alpha.-Trifluoro-m-tolyl)anthranilic acid, Anthranilic acid, N-(.alpha.,.alpha.,.alpha.-trifluoro-m-tolyl)-

ID: 1296

InChIKey: LPLVUJXQOOQHMX-QWBHMCJMSA-N
SMILES: C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"KA Teske" "JW Hanrahan" "Y Luo" "R Robert" "DY Thomas" "D Zhang" "GW Carlile"

CID is 14982
synonyms found at PubChem are:
Glycyrrhizic acid, glycyrrhizin, Glycyrrhizinic acid, 1405-86-3, Glycyron, Glycyrrhetinic acid glycoside, glyzyrrhizin, 18beta-Glycyrrhizic acid, 18-beta-Glycyrrhizic acid, Glycyrrizin, Liquorice, UNII-6FO62043WK, Rizinsan K2 A2 (free acid), HSDB 496, EINECS 215-785-7, C42H62O16, Glycyrrhizin [JAN], NSC 167409, NSC 234419, BRN 0077922, CHEMBL441687, NSC 2800, beta-Glycyrrhizin, CHEBI:15939, Dipotassium glycyrrhizinate, 6FO62043WK, DSSTox_CID_27006, DSSTox_RID_82047, DSSTox_GSID_47006, Glycyram, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, 20beta-Carboxy-11-oxo-30-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, 30-hydroxy-11,30-dioxoolean-12-en-3beta-yl (2-O-beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosiduronic acid, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuron osyl-, Glizigen, Neo-Umor, Zinc Glycyrrhizate, (3beta,20beta)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1- 7-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1- 7-glucopyranuronosyl-, CAS-1405-86-3, Glycyrrhizin (Glycyrrhizic Acid), potenlini, Glycyrrhizicacid, CCRIS 8444, NSC-167409, NSC-234419, NCGC00183128-01, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxy-tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid, Glycyrrhizic acid, 2K, beta-Glycyrrhizinic acid, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxy-tetrahydropyran-3-yl]oxy-3,4,5-trihydr, D0T8QB, AC1L24WN, AC1Q5R7O, Glycyrrhizia uralensis Fisch, SCHEMBL17684, 4-18-00-05156 (Beilstein Handbook Reference), BIDD:ER0363, GTPL4688, DTXSID8047006, LPLVUJXQOOQHMX-QWBHMCJMSA-N, MolPort-006-113-280, HY-N0184, Tox21_111520, Tox21_113426, Tox21_303493, BDBM50185127, s2302, ZINC96015174, AKOS015893086, AKOS015969345, CS-7695, GM-1292, NCGC00257455-01, NCGC00386162-02, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-, AN-40676, AS-13001, CC-29044, E958, LS-72973, KB-276753, ST2419401, FT-0080165, G0150, N1792, J10040, AB01566834_01, 405G863, C-23548, I04-1276, Q-201172, BRD-K83486494-318-01-5, (2S,3S,4S,5R,6R)-6-(((2S,3R,4S,5S,6S)-6-carboxy-2-(((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,1, (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid, (2S,3S,4S,5R,6S)-6-{[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-5-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid, (3.beta.,20.beta.)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-.beta.-1- 7-glucopyranuronosyl-.alpha.-D-glucopyranosiduronic acid, 1208112-19-9, 139014-59-8, 18933-02-3, 2a,14,14a,14b-icosahydropicen-3-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, 31261-47-9, 47897-45-0, 47897-48-3, 70055-50-4, 79165-07-4, 947339-02-8

ID: 1297

InChIKey: LPRLDRXGWKXRMQ-UHFFFAOYSA-N
SMILES: CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 66063
synonyms found at PubChem are:
Diphenylpyraline hydrochloride, 132-18-3, Allerzine, Histalert, Diaphen, Diphenylpyraline HCl, Sumadil, Diafen hydrochloride, Belfene hydrochloride, Hispril hydrochloride, Lergoban, 4-Diphenylmethoxy-1-methylpiperidine hydrochloride, Diphenpyraline hydrochloride, Diafen (antihistamine), UNII-G9FU7F1E87, 4-Diphenylmethoxy-1-methylpiperidine HCl, Diphenylpyraline (hydrochloride), EINECS 205-049-3, NSC 61825, 1-Methylpiperidyl-4-benzhydrylether hydrochloride, MLS000069803, G9FU7F1E87, P 253, 1-Methyl-4-piperidyl benzhydryl ether hydrochloride, Diphenylpyraline hydrochloride [JAN], 4-(Diphenylmethoxy)-1-methylpiperidine hydrochloride, Piperidine, 4-(diphenylmethoxy)-1-methyl-, hydrochloride, SMR000059141, DSSTox_CID_27752, DSSTox_RID_82529, DSSTox_GSID_47772, Piperidine, 4-diphenylmethoxy-1-methyl-, hydrochloride, 4-DIPHENYLMETHOXY-1-METHYLPIPERIDINE, Aerogastol, Anginosan, Piperidine, 4-(diphenylmethoxy)-1-methyl-, hydrochloride (1:1), Diphenylpyraline hydrochloride (JAN), CHEBI:31508, NSC61825, 4-benzhydryloxy-1-methylpiperidine;hydrochloride, NCGC00016395-01, CAS-132-18-3, C19H23NO.ClH, 4-(diphenylmethoxy)-1-methylpiperidine, chloride, SR-01000721836, Prestwick_969, Hispril (TN), Diafen, antihistamine, Diphenylpyraline hydrochloride [USP:JAN], Opera_ID_182, AC1L24JH, C19H23NO.HCl, CHEMBL1564, labotest-bb lt00159897, MLS001148620, MLS002222284, SCHEMBL212198, SPECTRUM1500258, 147-20-6 (Parent), DTXSID7047772, CTK8G8103, MolPort-003-666-168, HMS1570M15, HMS1920I08, Pharmakon1600-01500258, HY-B0970, Tox21_110419, 2169AH, CCG-40200, NSC-61825, NSC756730, AKOS022180771, Tox21_110419_1, AC-9856, CS-4455, NSC-756730, 4-benzhydryloxy-1-methyl piperidine hcl, NCGC00016395-06, NCGC00094658-01, NCGC00094658-02, AN-43686, AS-37666, DB-042095, KB-191247, LS-115275, FT-0625284, ST50319968, 4-BENZHYDRYLOXY-1-METHYLPIPERIDINE HCl, VU0244457-6, D01172, 4-benzhydryloxy-1-methyl-piperidine hydrochloride, 4-benzhydryloxy-1-methylpiperidine hydrochloride, 4-diphenylmethoxy-1-methylpiperidine hydrochlorid, 4-(Benzhydryloxy)-1-methylpiperidine hydrochloride, C-49657, J-006136, SR-01000721836-4, 4-Diphenylmethoxy-1-methylpiperidine hydrochloride, 95%, 4-benzhydryloxy-1-methylpiperidine~diphenylpyraline hydrochloride, 4-DIPHENYLMETHOXY-1-METHYLPIPERIDINE HYDROCHLORIDE MONOHYDRATE, Diphenylpyraline Hydrochloride 1.0 mg/ml in Methanol (as free base), SBB057419, AKOS025116945, MCULE-1496893365, 4-(diphenylmethoxy)-1-methylpiperidinium chloride, AKOS015915038, A806391, I14-7012, 4-(diphenylmethyl)oxy-1-methyl-piperidine; hydron; chloride, 4-(diphenylmethyl)oxy-1-methylpiperidine; hydron; chloride

ID: 1298

InChIKey: LPWVUDLZUVBQGP-DHZHZOJOSA-N
SMILES: C1=CC=C(C=C1)/C(=C\C2=C(NC3=CC(=CC(=C32)Cl)Cl)C(=O)O)/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6603913
synonyms found at PubChem are:
Mdl 105519, MDL 105,519, 161230-88-2, MDL-105519, (E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid, Lopac-M-216, D0X5PX, AC1O7G4O, Lopac0_000805, C18H11Cl2NO4, SCHEMBL499902, CHEMBL180427, AOB5684, HMS3262B11, ZINC1540415, Tox21_500805, AKOS027324667, CCG-204889, CS-3882, LP00805, NCGC00015639-01, NCGC00015639-02, NCGC00015639-03, NCGC00015639-04, NCGC00094138-02, NCGC00261490-01, HY-15085, EU-0100805, M-216, X6860, SR-01000075460, SR-01000075460-1, (Z)-2-Carboxy-4,6-dichloroindole-3-(2'-phenyl-2'-carboxy)-ene, (E)-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1H-indole-2-carboxylic acid, 4,6-dichloro-3-[(E)-3-hydroxy-3-oxo-2-phenylprop-1-enyl]-1H-indole-2-carboxylic acid

ID: 1299

InChIKey: LPXQRXLUHJKZIE-UHFFFAOYSA-N
SMILES: C12=NNNC1=NC(=NC2=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 8646
synonyms found at PubChem are:
8-AZAGUANINE, 134-58-7, Guanazolo, Azaguanine-8, Azaguanine, Guanazol, Pathocidin, Pathocidine, Triazologuanine, Azan, 8 AG, 5-Amino-1H-v-triazolo(d)pyrimidin-7-ol, 5-Amino-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one, AZG, SK 1150, 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine, NSC-749, 5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one, 5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one, 5-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol, SF-337, 2-Amino-6-oxy-8-azapurine, C4H4N6O, NSC 223526, CCRIS 2758, NSC749, 2-Amino-6-hydroxy-8-azapurine, B-28, CHEBI:63486, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-1,4-dihydro-, 8-AzaG, NSC 749, 5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol, AZAGUANINE,8, UNII-Q150359I72, v-Triazolo(4,5-d)pyrimidin-7-ol, 5-amino-, EINECS 205-148-1, 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one, AI3-25015, MLS001074752, LPXQRXLUHJKZIE-UHFFFAOYSA-N, 5-Amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,4-dihydro-, MFCD00056937, NSC223526, SMR000112575, 7H-v-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,6-dihydro-, 5-Amino-1H-triazolo(4,5-d)pyrimidin-7-ol, Q150359I72, 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one, v-Triazolo[4, 5-amino-, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, 5-imino-4,6-dihydro-3H-1,2,3-triazolo[5,4-d]pyrimidin-7-one, 7H-1,2,3-Triazolo(4,5-d)pyrimidinone, 5-amino-1,4-dihydro-, WLN: T56 BNNM FVM INJ HZ, 5-AMINO-3,6-DIHYDRO-(1,2,3)TRIAZOLO(4,5-D)PYRIMIDIN-7-ONE, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,6-dihydro-, 7H-v-Triazolo[4, 5-amino-1,6-dihydro-, 7H-1,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-1,4-dihydro-, 8-azaguanin, Azaguanine, 8, Prestwick_40, degrees (c)E cent, ACMC-1BSCA, AC1Q6AZZ, Prestwick0_000001, Prestwick1_000001, Prestwick2_000001, Prestwick3_000001, D01OHV, Epitope ID:167837, NCIMech_000065, AC1L1RF4, AC1Q52ZT, cid_8646, Oprea1_163604, Oprea1_695327, Oprea1_862850, SCHEMBL26816, BSPBio_000001, KSC519E8N, SPBio_001922, BPBio1_000003, CHEMBL374107, Jsp002100, DTXSID0074508, SCHEMBL16056969, BDBM96998, CTK4B9286, CTK7D5145, MolPort-002-047-086, MolPort-002-507-918, MolPort-004-963-947, MolPort-005-974-065, MolPort-009-199-364, MolPort-015-161-801, HMS1568A03, HMS2095A03, HMS2269M18, HMS3652J09, HMS3712A03, ML068, ALBB-023426, HY-B1468, KS-00000IS4, ANW-19689, CCG-35353, s4194, SBB000107, STK961684, ZINC96321491, AKOS002271137, AKOS003382261, AKOS006223655, AKOS015854480, AKOS022504735, AKOS026750385, AKOS028109237, CCG-220001, DB01667, MCULE-1863790805, NSC-223526, VZ35729, NCGC00016399-01, NCGC00188264-01, AJ-50842, AN-43735, DS-16103, NCI60_041639, SC-09024, ST025228, ST088035, LS-156822, A0625, CS-0013169, FT-0621501, K-4258, 134A587, AP-770/40205766, SR-01000763820, 2- degrees +/->>u-6-No-8-micro feminineOOaNssE, 5-amino-3,6-dihydrotriazolo[4,5-d]pyrimidin-7-one, 5-amino-3H-1,2,3-triazolo[5,4-d]pyrimidin-7-ol, Q-200564, SR-01000763820-2, 2- degrees +/->>u-6-oC>>u-8-micro feminineOOaNssE, I14-51392, 3H-1,2,3-triazolo[4,5-d]pyrimidin-7-ol, 5-amino-, 5-amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-azanyl-2,3-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, {7H-v-Triazolo[4,5-d]pyrimidin-7-one,} 5-amino-1, 6-dihydro-, 5-Amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one #, 7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-, {7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,} 5-amino-1,4-dihydro-, 5-imino-3,4,5,6-tetrahydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,4-dihydro- (9CI), 8-Azaguanine, Hybri-Max(TM), gamma-irradiated, powder, BioXtra, suitable for hybridoma, 1850358-61-0

ID: 1300

InChIKey: LPYUENQFPVNPHY-UHFFFAOYSA-N
SMILES: COC1=CC=CC(=C1O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 13622
synonyms found at PubChem are:
3-METHOXYCATECHOL, 3-methoxybenzene-1,2-diol, 934-00-9, 2,3-Dihydroxyanisole, 3-Methoxypyrocatechol, 1,2-Benzenediol, 3-methoxy-, Pyrocatechol, 3-methoxy-, Pyrogallol 1-methyl ether, 6-Methoxycatechol, 1,2-Dihydroxy-3-methoxybenzene, Pyrogallol 1-monomethyl ether, 3-Methoxy-1,2-benzenediol, NSC 66525, UNII-IC13U5393C, CCRIS 7577, 1-O-Methylpyrogallol, 3-Methoxy-o-hydroquinone, EINECS 213-276-4, 3-methoxy-benzene-1,2-diol, AI3-21349, 3-(methyloxy)benzene-1,2-diol, LPYUENQFPVNPHY-UHFFFAOYSA-N, IC13U5393C, NSC66525, Benzenediol, methoxy-, Spectrum_001637, ACMC-209rlk, SpecPlus_000921, DSSTox_CID_826, Spectrum2_001917, Spectrum3_001181, Spectrum4_001656, Spectrum5_000531, 3-Methoxycatechol, 99%, DSSTox_RID_75812, DSSTox_GSID_20826, SCHEMBL67332, BSPBio_002821, KBioGR_002151, KBioSS_002117, 1,2-Benzenediol,3-methoxy-, DivK1c_007017, SPECTRUM1600919, SPBio_001914, AC1L224C, CHEMBL1518159, DTXSID4020826, CTK0B2528, KBio1_001961, KBio2_002117, KBio2_004685, KBio2_007253, KBio3_002321, CHEBI:141700, MolPort-000-881-748, Pyrocatechol, 3-methoxy- (8CI), ZINC391919, Tox21_200504, 5842AC, ANW-40038, CCG-38485, NSC-66525, AKOS000121420, LS-7495, RTR-029257, SDCCGMLS-0066910.P001, NCGC00095761-01, NCGC00095761-02, NCGC00095761-03, NCGC00258058-01, AJ-21172, AN-22265, AS-48298, BP-20353, CAS-934-00-9, SC-28664, ZB012123, AB1007388, DB-057398, ST2417771, TR-029257, FT-0616000, M0524, ST50331820, A844580, SR-05000002377, S01-0323, SR-05000002377-1, BRD-K97139501-001-03-3, F0001-2249, InChI=1/C7H8O3/c1-10-6-4-2-3-5(8)7(6)9/h2-4,8-9H,1H, 1,2-Dihydroxy-3-methoxybenzene; 3-Methoxypyrocatechol; Pyrogallol monomethyl ether, 145929-30-2

ID: 1301

InChIKey: LQARHQHLYDRCTA-UHFFFAOYSA-N
SMILES: C(C1=CC=C(C)S1)1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazzei" "MT Mazzei" "F Cateni" "M Giampieri" "N Pedemonte" "P Fossa" "LJ Galietta" "M Zacchigna"

CID is 10313994
synonyms found at PubChem are:
dimethyl 2,6-dimethyl-4-(5-methyl-2-thienyl)-1,4-dihydropyridine-3,5-dicarboxylate, 162229-15-4, CHEMBL609004, MolPort-028-956-834, ALBB-027588, ZX-AN051841, ZINC38482642, AKOS015997555, MCULE-6729314642, T6016, 1,4-Dihydro-2,6-dimethyl-4-(5-methylthiophen-2-yl)pyridine-3,5-dicarboxylic acid dimethyl ester, 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(5-methyl-2-thienyl)-, dimethyl ester

ID: 1302

InChIKey: LQGUBLBATBMXHT-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10208
synonyms found at PubChem are:
Chrysophanol, 481-74-3, CHRYSOPHANIC ACID, 3-Methylchrysazin, 1,8-Dihydroxy-3-methylanthraquinone, Turkey rhubarb, Crysophanic acid, 1,8-dihydroxy-3-methylanthracene-9,10-dione, C.I. Natural Yellow 23, NSC 37132, NSC 646567, 1,8-Dihydroxy-3-methyl-9,10-anthracenedione, 4,5-Dihydroxy-2-methylanthraquinone, Crysophanol, UNII-N1ST8V8RR2, C.I. 75400, 2-Methyl-4,5-dihydroxyanthraquinone, 3-Methyl-1,8-dihydroxyanthraquinone, 1,8-Dihydroxy-3-Methyl-Anthraquinone, CCRIS 3525, CHEBI:3687, EINECS 207-572-2, 9,10-Anthracenedione, 1,8-dihydroxy-3-methyl-, N1ST8V8RR2, Anthraquinone, 1,8-dihydroxy-3-methyl-, Chrysophanic acid (1,8-dihydroxy-3-methylanthraquinone), 1,8-dihydroxy-3-methyl-9,10-anthraquinone, 1,8-Dihydroxy-3-methylanthra-9,10-quinone, LQGUBLBATBMXHT-UHFFFAOYSA-N, NSC-37132, NSC646567, NSC-646567, 1,8-dihydroxy-3-methyl-anthracene-9,10-dione, Q-100527, 9,10-Anthracenedione, 1,8-dihydroxy-3-methyl- (9CI), Archinin, Rumicin, Chrysophansaeure, Spectrum_000792, Chrysophanic Acid,(S), SpecPlus_000321, AC1L1UPN, AC1Q2QPQ, Spectrum2_000043, Spectrum3_001183, Spectrum4_001477, Spectrum5_000153, DSSTox_CID_4832, DSSTox_RID_77547, DSSTox_GSID_24832, BSPBio_002825, KBioGR_002053, KBioSS_001272, SPECTRUM300545, MLS000574888, CHEMBL41092, DivK1c_006417, SCHEMBL308131, SPBio_000165, 9, 1,8-dihydroxy-3-methyl-, Chrysophanic acid (Chrysophanol), Chrysophanic acid - Chrysophanol, DTXSID6024832, Chrysophanol, analytical standard, CTK3J0577, KBio1_001361, KBio2_001272, KBio2_003840, KBio2_006408, KBio3_002325, MolPort-000-165-353, HMS3656G17, BCP23439, KS-00000MG7, NSC37132, ZINC3861630, Tox21_202499, Anthraquinone,8-dihydroxy-3-methyl-, ANW-41898, BDBM50455992, CC0160, CCG-38348, LMPK13040006, MFCD00001208, s2406, SBB012460, 3-Methyl-1, 8-dihydroxyanthraquinone, 4, 5-Dihydroxy-2-methylanthraquinone, AKOS015905000, AC-7980, AN-8463, API0002002, BCP9000004, DS-9706, LS-1289, MCULE-5296458901, RTR-031338, SDCCGMLS-0066504.P001, NCGC00091823-01, NCGC00091823-02, NCGC00091823-03, NCGC00091823-04, NCGC00091823-05, NCGC00260048-01, AJ-46213, AK160262, AN-41445, CAS-481-74-3, HY-13595, SC-25739, SMR000156239, ST072177, 1,8-Dihydroxy-3-methylanthraquinone, 98%, AB0019714, AX8006265, TR-031338, 8,9-dihydroxy-6-methyl-1,10-anthraquinone, A7529, FT-0623813, N1852, ST24046322, V0177, NSC 37132?NSC 646567?, 1,8-Dihydroxy-3-methylanthra-9,10-quinone #, C10315, Z-3173, 481C743, SR-01000712223, 1,8-Dihydroxy-3-methyl-9,10-anthracenedione, 9CI, SR-01000712223-2, BRD-K59284035-001-02-0, BRD-K59284035-001-03-8

ID: 1303

InChIKey: LQLZHYNOLPBEKL-UHFFFAOYSA-N
SMILES: CC1=NN(C(=O)C1)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10855552
synonyms found at PubChem are:
57303-41-0, SCHEMBL11595302, CTK6B3161, AKOS006338515, 3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carboxamide, 1H-Pyrazole-1-carboxamide, 4,5-dihydro-3-methyl-5-oxo- (9CI), 3-METHYL-5-OXO-4,5-DIHYDRO-PYRAZOLE-1-CARBOXYLICACID AMIDE

ID: 1304

InChIKey: LQRTZZUNSKIADN-UHFFFAOYSA-N
SMILES: C1C(=NN(C1=O)C(=S)N)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 274131
synonyms found at PubChem are:
MLS002706953, 58197-04-9, 1H-Pyrazole-1-carbothioamide, 4,5-dihydro-5-oxo-3-phenyl-, 5-oxo-3-phenyl-4H-pyrazole-1-carbothioamide, NSC119927, AC1MC3S3, CHEMBL1732527, CTK8J4523, DTXSID40369108, LQRTZZUNSKIADN-UHFFFAOYSA-N, ZINC4787512, AKOS024333055, MCULE-4426221914, NSC-119927, SMR001574349, 3-Phenyl-1-thiocarbamoyl-2-pyrazolin-5-on, 1H-Pyrazole-1-carbothioamide,5-dihydro-5-oxo-3-phenyl-, 4,5-Dihydro-5-oxo-3-phenyl-1H-pyrazole-1-carbothioamide, 5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide, 5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide #

ID: 1305

InChIKey: LRBQNJMCXXYXIU-PPKXGCFTSA-N
SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)OC2=CC(=CC(=C2O)O)C(=O)OC[C@@H]3[C@H]([C@@H]([C@H]([C@@H](O3)OC(=O)C4=CC(=C(C(=C4)OC(=O)C5=CC(=C(C(=C5)O)O)O)O)O)OC(=O)C6=CC(=C(C(=C6)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)OC(=O)C8=CC(=C(C(=C8)OC(=O)C9=CC(=C(C(=C9)O)O)O)O)O)OC(=O)C1=CC(=C(C(=C1)OC(=O)C1=CC(=C(C(=C1)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16129778
synonyms found at PubChem are:
TANNIC ACID, 1401-55-4, Gallotannic acid, MLS001335996, CHEBI:81066, 5424-20-4, SMR000857330, DSSTox_CID_6076, DSSTox_RID_78006, DSSTox_GSID_26076, Quebracho extract, MFCD00066397, CAS-1401-55-4, Tanninum, Chinese gallotannin, NCGC00095101-01, Gallotannin; Tannin, EINECS 226-562-9, C76H52O46, Tannic acid, technical, Tannic acid, ACS reagent, D0R4WJ, Tannic acid, technical grade, MLS001335995, SCHEMBL409692, Tannic acid, SAJ first grade, CHEMBL506247, GTPL4319, BDBM60986, Tannic acid, puriss., 95.0%, cid_16129778, LRBQNJMCXXYXIU-PPKXGCFTSA-N, MolPort-006-116-866, Tox21_111422, Tox21_300079, BDBM50442879, AKOS015951319, Tannic acid, Vetec(TM) reagent grade, AN-8415, RL01715, beta-D-Glucose pentakis(3,4-dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoate), NCGC00186054-01, NCGC00186054-02, NCGC00253925-01, SC-80506, Tannic acid, tested according to Ph.Eur., AB1009468, C17409, Tannic acid, Source: Chinese natural gall nuts, Q-201780, Tannic acid, puriss., meets analytical specification of USP, powder, Tannic acid, United States Pharmacopeia (USP) Reference Standard, .Beta.-D-glucopyranose, pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate], beta-D-Glucopyranose pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate], (2R,3R,4S,5R,6S)-4,5,6-tris({3,4-dihydroxy-5-[(3,4,5-trihydroxyphenyl)carbonyloxy]phenyl}carbonyloxy)-2-[({3,4-dihydroxy-5-[(3,4,5-trihydroxyphenyl)carbonyloxy]phenyl}carbonyloxy)methyl]oxan-3-yl 3,4-dihydroxy-5-[(3,4,5-trihydroxyphenyl)carbonyloxy]benzoate, [2,3-dihydroxy-5-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis[[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyl)oxy-benzoyl]oxy]tetrahydropyran-2-yl]methoxycarbonyl]phenyl] 3,4,5-trihydroxybenzoate

ID: 1306

InChIKey: LRFYCTLMXJJJHZ-UHFFFAOYSA-N
SMILES: CC(=O)OC1CCC2(CC1(CCC3C2CC3(C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3955970
synonyms found at PubChem are:
SENECRASSIDIOL 6-ACETATE, SPBio_000312, Spectrum_000638, SpecPlus_000188, Spectrum2_000316, Spectrum3_001271, Spectrum4_001447, Spectrum5_000033, BSPBio_002862, KBioGR_001933, KBioSS_001118, SPECTRUM300052, DivK1c_006284, AC1N021L, KBio1_001228, KBio2_001118, KBio2_003686, KBio2_006254, KBio3_002362, 155488-34-9, CCG-38592, SDCCGMLS-0066496.P001, NCGC00095575-01, NCGC00095575-02

ID: 1307

InChIKey: LRPUAFALRBYLTA-UHFFFAOYSA-N
SMILES: CN1CCC=C(C1)C(=O)OCC#C.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 189406
synonyms found at PubChem are:
Arecaidine propargyl ester hydrobromide, 116511-28-5, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, 2-propyn-1-yl ester, hydrobromide, APE, 1-Methyl-1,2,5,6-tetrahydro-3-pyridine carboxylic acid propargyl ester hydrobromide, 3-Pyridinecarboxylicacid, 1,2,5,6-tetrahydro-1-methyl-, 2-propyn-1-yl ester, hydrobromide (1:1), ACMC-20d1dg, EU-0100136, AC1L4ON0, AC1Q62JP, MLS002153370, CHEMBL1255649, CTK4A9829, DTXSID90151414, LRPUAFALRBYLTA-UHFFFAOYSA-N, Tox21_500136, MFCD00078566, AKOS030566243, API0007810, CCG-221440, LP00136, prop-2-yn-1-yl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide(1:1), NCGC00093626-01, NCGC00260821-01, SMR000326890, Arecaidine propargyl ester hydrobromide(ape), RT-011316, A-140, Arecaidine propargyl ester hydrobromide, solid, ARECAIDINE PROPARGYL ESTER HYDROBROMIDE (APE), J-003450, SR-01000075301-1, prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate hydrobromide

ID: 1308

InChIKey: LRQIVCBYMGMPLT-XFULWGLBSA-N
SMILES: C=CCN1CCC2=CC=CC3=C2[C@H]1CC4=C3C(=C(C=C4)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957524
synonyms found at PubChem are:
R(-)-N-Allylnorapomorphine hydrobromide, CHEMBL542493, EU-0100406, MLS001178646, LP00406, SMR000477399, D-042, SR-01000075375, SR-01000075375-1

ID: 1309

InChIKey: LSHVYAFMTMFKBA-TZIWHRDSSA-N
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Yu" "Y Zhang" "L Zhu" "X Gao" "H Yang" "T Ma" "L Chen"

CID is 107905
synonyms found at PubChem are:
(-)-Epicatechin gallate, 1257-08-5, Epicatechin gallate, (-)-Epicatechin-3-O-gallate, L-Epicatechin gallate, (-)-Epicatechin-3-gallate, (-)-epicatechingallate, epicatechin monogallate, (-)-Epicatechin 3-O-gallate, Teatannin, Epicatechol, gallate, UNII-92587OVD8Z, 3-O-Galloylepicatechin, 3-Gallate(-)-Epicatechol, epicatechin gallate, (2R-cis)-isomer, NSC 636594, (-)-cis-3,3',4',5,7-Pentahydroxyflavane 3-gallate, CHEMBL36327, (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, ECG, CHEBI:70255, LSHVYAFMTMFKBA-TZIWHRDSSA-N, 92587OVD8Z, C22H18O10, epicatechin-3-O-gallate, Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2R-cis)-, (-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate, (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate, [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate, [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, epi-Catechin 3-O-gallate, Epicatechol, gallate (6CI), NSC636594, (-)epicatechingallate, Epicatechin 3-gallate, Spectrum_000314, SpecPlus_000275, (-) epicatechin gallate, Spectrum2_000165, Spectrum3_000246, Spectrum4_001540, Spectrum5_000080, epicatechin gallate (ECG), (-)-Epicatechin gallate,, AC1L32YN, 3-Galloyl-(-)-epicatechin, SCHEMBL39047, BSPBio_001632, KBioGR_001980, KBioSS_000794, SPECTRUM210238, (-)-Epicatechin-3-gallate,, DivK1c_006371, SPBio_000029, AC1Q5X10, MEGxp0_000810, (-)-epi-Catechin 3-O-gallate, (-)-Epicatechin-3-O-gallate,, CTK8E0233, Epicatechol, 3-gallate, (-)-, KBio1_001315, KBio2_000794, KBio2_003362, KBio2_005930, KBio3_001132, 3,4,5-Trihydroxy-benzoic acid 2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester, MolPort-001-740-964, HY-N0002, ZINC3978503, BDBM50153015, CCG-38376, CE0014, LMPK12020090, MFCD00075936, AKOS015965216, AC-6037, AM84365, CS-3761, MCULE-8110076741, SDCCGMLS-0066549.P001, 3-Galloyl-(2R,3R)-(-)-Epicatechin, Epicatechol, 3-gallate, (-)- (8CI), NCGC00179135-01, AJ-47571, AN-48941, AS-15722, LS-38401, Q429, AB0017581, AX8001457, KB-277863, E0890, ST24033389, 257E085, C-22380, SR-05000002675, Q-200002, SR-05000002675-1, BRD-K50660797-001-01-0, BRD-K50660797-001-03-6, (-)-Epicatechin gallate, >=98% (HPLC), from green tea, UNII-T432289GYZ component LSHVYAFMTMFKBA-TZIWHRDSSA-N, Epicatechin gallate, primary pharmaceutical reference standard, [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl] 3,4,5-trihydroxybenzoate, (-)-cis-3,3 inverted exclamation marka,4 inverted exclamation marka,5,7-Pentahydroxyflavane 3-gallate, (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate, 3,4,5-Trihydroxy-benzoic acid (2R,3R)-2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester, 3,4,5-Trihydroxybenzoic Acid (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl Ester, Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7- dihydroxy-2H-1-benzopyran-3-yl ester, (-)-cis-

ID: 1310

InChIKey: LSQZJLSUYDQPKJ-NJBDSQKTSA-N
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 33613
synonyms found at PubChem are:
amoxicillin, Amoxycillin, Amoxicillin anhydrous, 26787-78-0, Amoxicilline, p-Hydroxyampicillin, Amoxicillinum, Amopenixin, Amoxicilina, Amolin, Moxal, D-Amoxicillin, Clamoxyl, AMPC, Delacillin, Histocillin, Amoclen, Amoxiden, Amoxivet, Anemolin, Aspenil, Bristamox, Cemoxin, Efpenix, Flemoxin, Hiconcil, Ibiamox, Imacillin, Moxacin, Piramox, Unicillin, Vetramox, Amoxi, Sumox, DisperMox, Amoxil, Polymox, Trimox, Wymox, Amoxi-Mast, Sawamox PM, Metafarma capsules, Metifarma capsules, Amopen, Ospamox, Robamox, Utimox, Amoxicilina [INN-Spanish], Amoxicilline [INN-French], Amoxicillinum [INN-Latin], Larotid, alpha-Amino-p-hydroxybenzylpenicillin, Actimoxi, Amoxicaps, Amoxicillin trihydrate, Hydroxyampicillin, Apo-Amoxi, Moxatag, AMOXICILLIN PEDIATRIC, Amoxycillin Trihydrate, AMOXICILLIN CRYSTALLINE, amoxicillanyl, Amoxibiotic, Pamoxicillin, Tolodina, Amoxicillin (anhydrous), Biomox, Lamoxy, 6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid, Amoxicilline [INN], BLP 1410, BRL-2333, D-(-)-alpha-Amino-p-hydroxybenzylpenicillin, Amoxicillin (TN), Amoxicillin (INN), Amoxicillin [INN], CHEBI:2676, Ro 10-8756, UNII-9EM05410Q9, HSDB 3204, D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid, EINECS 248-003-8, BL-P 1410, 6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin, NSC 277174, (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid, 9EM05410Q9, (-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid, (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Amoxicillin hydrate, Dispermox (TN), Amoxil (TN), AMOX, DSSTox_CID_17044, DSSTox_RID_79299, DSSTox_GSID_37044, (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, AX, 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid, (2S,5R,6R)-6-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, 4-Thia-1-azobicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S)))-, SMR000058707, Amoxicillin (Amoxycillin), amocilline, amoxcillin, amoxycilin, Amoxi-Inject, Amoxi-Tabs, NSC277174, Amoksiklav (TN), Betalaktam (TN), Amoksibos (TN), Amoxiclav (TN), Augmentin (TN), Gimalxina (TN), Novamoxin (TN), Sinacilin (TN), Amoxibiotic (TN), Amoxicilina (TN), NCGC00016797-02, NCGC00094586-01, Actimoxi (TN), Alphamox (TN), Amoxidal (TN), Enhancin (TN), Hiconcil (TN), Isimoxin (TN), Nobactam (TN), Tolodina (TN), (2S,5R,6R)-6-(2-Amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Pamoxicillin (TN), Prestwick_713, Cilamox (TN), Dedoxil (TN), Geramox (TN), Moxatag (TN), Moxilen (TN), Moxypen (TN), Moxyvit (TN), Ospamox (TN), Panamox (TN), Panklav (TN), Polymox (TN), Zerrsox (TN), Amoxin (TN), Bactox (TN), CAS-26787-78-0, Duomox (TN), Klavox (TN), Lamoxy (TN), Sandoz (TN), Trimox (TN), Apo-Amoxi (TN), Samthongcillin (TN), Curam (TN), Senox (TN), Wymox (TN), Yucla (TN), Zimox (TN), Prestwick0_000357, Prestwick1_000357, Prestwick2_000357, Prestwick3_000357, D0F6EO, Epitope ID:114241, Epitope ID:116054, EC 248-003-8, AC1L1PY2, AMK (TN), SCHEMBL3427, CHEMBL1082, BSPBio_000453, MLS000028632, MLS002222248, SPBio_002374, BPBio1_000499, DTXSID3037044, CHEBI:53712, HY-B0467A, LSQZJLSUYDQPKJ-NJBDSQKTSA-N, MolPort-005-933-687, HMS1569G15, HMS2096G15, HMS2231K23, HMS3259P17, HMS3713G15, KS-00000Q8R, ZINC3830215, Tox21_111302, BDBM50350464, s3015, AKOS025395540, Tox21_111302_1, CCG-220357, CS-2612, DB01060, DS-3835, MCULE-5710225015, NC00670, NE41275, 61336-70-7 (TRIHYDRATE), NCGC00179554-01, 34642-77-8 (mono-hydrochloride salt), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-, AC-12263, AJ-75350, Amoxicillin, potency: >=900 mug per mg, AN-39271, BC204303, CPD000058707, SAM002264592, SC-13298, LS-149721, FT-0602856, ST24034193, C06827, D07452, SR-01000721886, SR-01000721886-2, BRD-K55044200-001-03-9, BRD-K55044200-001-15-3, Actimoxi, Alphamox, Amocla,Tycil, Amoxil, Trimox, among others, 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl, 1236363-38-4, 33911-69-2, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D-(8CI), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[amino (4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2.alpha.,5.alpha.,6.beta.(S*)]]-, 71447-36-4, 81030-75-3

ID: 1311

InChIKey: LSTPKMWNRWCNLS-UHFFFAOYSA-N
SMILES: C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2071
synonyms found at PubChem are:
AIDA, 168560-79-0, UPF 523, 1-Aminoindan-1,5-dicarboxylic acid, GNF-PF-1401, 1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid, CHEMBL313938, UPF523, 1-amino-2,3-dihydroindene-1,5-dicarboxylic acid, 1-Aminoindan-1, 5-dicarboxylic acid, 1H-Indene-1,5-dicarboxylic acid, 1-amino-2,3-dihydro-, Indan-1,5-dicarboxylic acid, 1-amino-, (RS)-1-Aminoindan-1,5-dicarboxylic acid, AIDA, solid, AIDC, AC1L1CUO, D04JKL, Lopac0_000119, SCHEMBL391979, AC1Q5U28, GTPL1376, CTK0H9243, MolPort-003-940-106, HMS3260G20, 1H-Indene-1,5-dicarboxylicacid, 1-amino-2,3-dihydro-, Tox21_500119, 1-aminoindane-1,5-dicarboxylic acid, BDBM50030630, BN0058, MFCD00672638, 1-Amino-indan-1,5-dicarboxylic acid, AKOS015903639, CCG-204214, LP00119, NCGC00015024-03, NCGC00015024-04, NCGC00015024-05, NCGC00015024-06, NCGC00024861-02, NCGC00024861-03, NCGC00024861-04, NCGC00260804-01, CC-03934, DB-043745, LS-186979, LS-187621, RT-011225, A-254, EU-0100119, FT-0643608, ST50825719, 1-Aminoindan-1,5-dicarboxylic acid; UPF 523, 1-Amino-indan-1,5-dicarboxylic acid(RS-AIDA), C-12266, L000102, SR-01000075427, J-010467, SR-01000075427-1, 1H-Indene-1,5-dicarboxylicacid,1-amino-2,3-dihydro-, I14-18398

ID: 1312

InChIKey: LTKVFMLMEYCWMK-UHFFFAOYSA-N
SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68540
synonyms found at PubChem are:
Amiloride hydrochloride dihydrate, 17440-83-4, Modamide, Nirulid, Amiloride HCL, Amiloride HCl dihydrate, Amilorid hydrochlorid-2-wasser, UNII-FZJ37245UC, Amiloride hydrochloride [USAN:USP], MK 870, MK-870, CHEBI:2640, FZJ37245UC, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate, AMIPRAMIDINE, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride dihydrate, C6H8ClN7O.HCl, 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide dihydrate hydrochloride, 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride dihydrate, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride dihydrate, 2609-46-3 (Parent), Amiloride hydrochloride [USAN], 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide;dihydrate;hydrochloride, Prestwick_15, Midamor (TN), Guanamprazine dihydrate, AC1Q3POE, AC1L29YD, C6H8ClN7O.HCl.2H2O, Amiloride hydrochloride (USP), AC1Q59C1, amiloride dihydrate hydrochloride, CHEMBL1398126, HY-B0285B, DTXSID80169826, Amipramidin hydrochloride dihydrate, LTKVFMLMEYCWMK-UHFFFAOYSA-N, MolPort-023-219-586, HMS1568A15, s2560, AKOS015994750, CCG-220007, CS-8162, KS-5132, VZ31250, 3,5-diamino-6-chloro-n-(diaminomethylidene)pyrazine-2-carboxamide hydrochloride dihydrate, NCGC00017086-01, BC677981, O373, AB2000656, CAS-17440-83-4, LS-173667, FT-0689194, D00649, EN300-119533, K-5905, J-010987, Z1541632803, 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide dihydrate hydrochloride, 3,5-Diamino-N-(aminomethyl)-6-chloropyrazine carboxamide hydrochloride dihydrate, Amiloride Hydrochloride Dihydrate 1.0 mg/ml in Methanol (as anhydrous free base), 2-?Pyrazinecarboxamide, 3,?5-?diamino-?N-?(aminoiminomethyl)?-?6-?chloro-?, hydrochloride, hydrate (1:1:2), AKOS015896598, I06-2275

ID: 1313

InChIKey: LTMHDMANZUZIPE-PUGKRICDSA-N
SMILES: C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

"F Ciciriello" "A Luini" "H Balghi" "JW Hanrahan" "R Robert" "DY Thomas" "A Carissimo" "D Zhang" "GW Carlile" "J Liao" "SM Anjos"

CID is 2724385
synonyms found at PubChem are:
digoxin, 20830-75-5, 12beta-Hydroxydigitoxin, Digoxine, Lanoxin, Lanoxicaps, Digosin, Digossina, Digoxina, Digoxinum, Lanoxicaps (TN), [3H]digoxin, Digacin, Dilanacin, Lanicor, Lanoxin (TN), [3H]-digoxin, CHEBI:4551, MLS000069819, Cardiogoxin, Lanacordin, Davoxin, Dynamos, Eudigox, Lanacrist, Lenoxin, Mapluxin, Rougoxin, SMR000059217, Vanoxin, Neo-Lanicor, Digoxin Nativelle, Digoxin Pediatric, Lanoxin PG, SK-Digoxin, UNII-73K4184T59, Homolle's digitalin, Hemigoxine Nativelle, NCGC00090797-03, 73K4184T59, DSSTox_CID_2934, Digoxin, analytical standard, DSSTox_RID_76794, Coragoxine, DSSTox_GSID_22934, Lenoxicaps, Neodioxanin, Acygoxin, Cardigox, Cardioxin, Cogoxin, Cordioxil, Digomal, Digonix, Dimecip, Fargoxin, Lanikor, Lanorale, Lifusin, Longdigox, Natigoxin, Purgoxin, Saroxin, Stillacor, (3beta,5beta,12beta)-3-{[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide, Dixina, Grexin, Digon, Digos, Dokim, Digoxina-Sandoz, Digoxin-Sandoz, Digoxin-Zori, Digitalis glycoside, Digitek, Digoxine Navtivelle, Novodigal [inj.], Digoksyna [Polish], Digossina [DCIT], NSC 95100, Chloroformic digitalin, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, LANOXIN PEDIATRIC, SMR000653537, Digoxinum [INN-Latin], Digoxina [INN-Spanish], HSDB 214, Digazolan, Digoksyna, Lanadicor, Digoxigenin-tridigitoxosid [German], EINECS 244-068-1, C41H64O14, BRN 0077011, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydr, 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one, Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-, oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, Prestwick_170, Digitek (TN), CAS-20830-75-5, 3b0w, 12bet.-Hydroxydigitoxin, AC1MC4TN, Digoxigenin-tridigitoxosid, Opera_ID_1134, Prestwick0_000437, Prestwick1_000437, Prestwick2_000437, Prestwick3_000437, Digoxin (JP15/USP), Digoxin (JP17/USP), D02OZE, D09YRM, Epitope ID:122964, AC1Q29PT, CHEMBL1751, BIDD:PXR0148, SCHEMBL20506, BSPBio_000454, MLS001055371, MLS001076495, SPBio_002393, BPBio1_000500, GTPL4725, GTPL4726, Digoxin [USP:INN:BAN:JAN], Digoxin 1.0 mg/ml in Methanol, DTXSID5022934, BDBM46355, cid_2724385, LTMHDMANZUZIPE-PUGKRICDSA-N, MolPort-002-536-760, REGID_for_CID_2724385, ZX-AFC001295, HMS1569G16, HMS2096G16, HMS2232G20, HMS3713G16, (3beta,5beta,12beta)-3-((O-2,6-Dideoxy-beta-D-ribo-hexapyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxycard-20(22)-enolide, 3beta-((O-2,6-Dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12beta,14-dihydroxy-5beta-card-20(22)-enolide, HY-B1049, Tox21_111025, Tox21_201678, Tox21_303050, MFCD00003674, s4290, AKOS015895113, AKOS024283494, ZINC242548690, CCG-220437, CS-4571, DB00390, MCULE-8165628529, NCGC00090797-01, NCGC00090797-02, NCGC00090797-04, NCGC00090797-05, NCGC00090797-06, NCGC00090797-07, NCGC00090797-09, NCGC00090797-15, NCGC00257022-01, NCGC00259227-01, AN-18552, AS-13281, CC-26802, H797, ST069334, B7684, D1828, OioC>>uNomicroO>>AE paragraph sign(3/4)UO, C06956, D00298, J10027, 5-18-04-00381 (Beilstein Handbook Reference), 830D755, A814956, C-23516, SR-01000721866, Digoxin, certified reference material, TraceCERT(R), J-013666, SR-01000721866-3, SR-01000721866-4, BRD-K23478508-001-03-7, Digoxin, European Pharmacopoeia (EP) Reference Standard, 0B9662A7-264E-4ACD-94B2-9E1138C0CA5A, Digoxin, United States Pharmacopeia (USP) Reference Standard, Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material, 3beta,12beta,14-Trihydroxy-5beta,14beta-card-20(22)-enolid-3-tridigitoxosid, Digoxin for peak identification, European Pharmacopoeia (EP) Reference Standard, Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, 11000-95-6, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-10,13-dimethyl-3-[(2R,4S,5S,6R)-6-methyl-5-[(2S,4S,5S,6R)-6-methyl-5-[(2S,4S,5S,6R)-6-methyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-12,14-bis(oxidanyl)-1,2,3,4,5,6,7,8,9,11,12,, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[[(2R,4S,5S,6R)-5-[[(2S,4S,5S,6R)-5-[[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyl-2-oxanyl]oxy]-4-hydroxy-6-methyl-2-oxanyl]oxy]-4-hydroxy-6-methyl-2-oxanyl]oxy]-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,, 36-35-1, 39366-41-1, 4-((1S,2S,5S,11S,15S,7R,10R,14R,16R)-5-{5-[5-((2S,4S,5S,6R)-4,5-dihydroxy-6-me thyl(2H-3,4,5,6-tetrahydropyran-2-yloxy))(4S,5S,2R,6R)-4-hydroxy-6-methyl(2H-3 ,4,5,6-tetrahydropyran-2-yloxy)](4S,5S,2R,, 4-((1S,2S,5S,11S,15S,7R,10R,14R,16R)-5-{5-[5-((2S,4S,5S,6R)-4,5-dihydroxy-6-me thyl(2H-3,4,5,6-tetrahydropyran-2-yloxy))(4S,5S,2R,6R)-4-hydroxy-6-methyl(2H-3 ,4,5,6-tetrahydropyran-2-yloxy)](4S,5S,2R,6R)-4-hydroxy-6-methyl(2H-3,4,5,6-te trahydropyran-2-yl, 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one, 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}, 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-5-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^, 4-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-4,5-dihydroxy-6-methyl-oxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one, 6R)-4-hydroxy-6-methyl(2H-3,4,5,6-te trahydropyran-2-yloxy)}-11,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0 <11,15>]heptadec-14-yl)-5-hydrofuran-2-one, 8001-36-3, 8001-37-4, 8001-52-3, 82476-60-6, Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-, Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1.fwdarw.4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1.fwdarw.4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-, Card-20(22)-enolide, 3-[[O-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1-->4)-O-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1-->4)-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl]oxy]-12,14-dihydroxy-, (3.beta.,5.beta.,12.beta.)-

ID: 1314

InChIKey: LTNZEXKYNRNOGT-UHFFFAOYSA-N
SMILES: CC1=[N+](C2=CC=CC=C2C(=C1)N)CCCCCCCCCC[N+]3=C(C=C(C4=CC=CC=C43)N)C.[Cl-].[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10649
synonyms found at PubChem are:
dequalinium chloride, 522-51-0, Dequalinium Dichloride, Dequafungan, Danical, Decabis, Decaminum, Decosan, Dekuarin, Eriosept, Erosept, Gorgine, Grocreme, Optipect, Phylletten, Angils, Efisol, Evazol, Vaster, Dequalinii chloridum, Decamine, Dekadin, Dekamin, Dequadin, Dequavagyn, Dequavet, Labosept, Oralgol, Polycidine, Rumilet, Sanoral, Sentril, Cloruro de decalinio, Ivazil, Sorot, DECA, BAQD 10, Dequalin chloride, Chlorure de dequalinium, Dequalinium (Chloride), Dynexan-mhp, Decamine (pharmaceutical), UNII-XYS8INN1I6, Dequalinio cloruro [DCIT], Dequalinum Chloride, 1,1'-Decamethylenebis(4-aminoquinaldinium chloride), Dequalinii chloridum [INN-Latin], Decamethylenebis(4-aminoquinaldinium chloride), Cloruro de decalinio [INN-Spanish], EINECS 208-330-9, Dequalinium chloride [INN:BAN:JAN], XYS8INN1I6, Chlorure de dequalinium [INN-French], NSC 166454, CHEBI:31466, Dequalinium chloride hydrate, 1,10-Decamethylene-bis(4-aminoquinaldinium chloride), Quinaldinium, 1,1'-decamethylenebis(4-amino)-, dichloride, 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride, W-105841, Quinaldinium, 1,1'-decamethylenebis(4-amino-, dichloride, Quinolinium, 1,1'-(1,10-decanediyl)bis(4-amino-2-methyl-, dichloride, Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride, CHEMBL121663, Dequalinio cloruro, 1,1 inverted exclamation marka-Decamethylenebis(4-aminoquinaldinium) dichloride, 6707-58-0 (Parent), C30H40N4, SR-01000075814, NCGC00015339-02, CAS-522-51-0, C30H40Cl2N4, 1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium-4-amine;dichloride, Nordman (TN), AC1L1VNG, DSSTox_CID_25144, DSSTox_RID_80700, DSSTox_GSID_45144, SCHEMBL34043, SPECTRUM1503127, DTXSID3045144, CTK8F9037, Dequalinium chloride (JAN/INN), HMS502F14, MolPort-003-665-566, HMS1569M17, HMS1922G11, HMS2096M17, HMS3261C17, HMS3713M17, BCP21273, HY-B0567, Tox21_110128, Tox21_500338, BN0180, s4066, AKOS015895242, API0014417, CCG-213734, CS-2676, LP00338, MCULE-5255183860, NCGC00093777-01, NCGC00093777-02, NCGC00093777-03, NCGC00261023-01, CC-26341, SC-22665, AB1003158, LS-139898, TL8003449, EU-0100338, FT-0603110, ST50981059, D 3768, D01575, C-23091, I06-0264, SR-01000075814-1, SR-01000075814-3, SR-01000075814-6, SR-01000075814-7, 1,1'-Decamethylenebis(4-aminoquinaldinium) dichloride, 1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM CHLORIDE, 1,1'-(decane-1,10-diyl)bis(4-amino-2-methylquinolinium) chloride, 1,1'-decane-1,10-diylbis(4-amino-2-methylquinolinium) dichloride, Dequalinium chloride, European Pharmacopoeia (EP) Reference Standard, 1-[10-(4-amino-2-methylquinolyl)decyl]-2-methyl-4-quinolylamine, chloride, chl oride, Dequalinium chloride for performance test, European Pharmacopoeia (EP) Reference Standard, Dequalinium chloride, Pharmaceutical Secondary Standard; Certified Reference Material, Quinolinium, 1,1'-(1,10-decanediyl)bis(4-amino-2-methyl-, dichloride (9CI), quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2), 1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium-4-amine dichloride, 1,1-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM CHLORIDE)

ID: 1315

InChIKey: LUALIOATIOESLM-UHFFFAOYSA-N
SMILES: C1CN(CCC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4747
synonyms found at PubChem are:
periciazine, Propericiazine, PERICYAZINE, Piperocyanomazine, Neuleptil, Nemactil, Neulactil, Periciazinum, Aolept, 2622-26-6, propericyazine, Periciazina, Bayer 1409, Periciazine [INN], propericiazine(jan), Periciazinum [INN-Latin], Periciazina [INN-Spanish], Nelactil, SKF 20,716, 6909 RP, IC 6002, RP 8908, WH 7508, 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine, 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile, Neuleptil (TN), 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine, Propericiazine (JAN), UNII-3405M6FD73, F.I. 6145, EINECS 220-071-3, Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine, BRN 0576739, Properazine, C21H23N3OS, CHEMBL251940, 4-Piperidinol, 1-(3-(2-cyano-10-phenothiazinyl)propyl)-, CHEBI:31981, Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine [French], 10H-Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxy-1-piperidinyl)propyl]-, 3405M6FD73, RP 8909, RP-8909, NCGC00095086-01, 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile, 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile, Phenothiazine-2-carbonitrile, 10-(3-(4-hydroxypiperidino)propyl)-, Phenothiazine-2-carbonitrile, 10-[3-(4-hydroxypiperidino)propyl]-, 10-(3-(4-Hydroxypiperidin-1-yl)propyl)-10H-phenothiazine-2-carbonitrile, properciazine, Periciazin, Neulactil (TN), PubChem2346, Spectrum_001614, AC1Q4RQI, Spectrum2_001604, Spectrum3_000748, Spectrum4_000210, Spectrum5_001747, D00AWT, AC1L1IV8, DSSTox_CID_25910, DSSTox_RID_81221, DSSTox_GSID_45910, BSPBio_002336, KBioGR_000819, KBioSS_002094, DivK1c_000874, SCHEMBL148422, SPECTRUM1503936, SPBio_001607, GTPL9216, DTXSID5045910, HMS502L16, KBio1_000874, KBio2_002094, KBio2_004662, KBio2_007230, KBio3_001556, LUALIOATIOESLM-UHFFFAOYSA-N, NINDS_000874, HMS1922M18, Pharmakon1600-01503936, ZINC538159, Tox21_111417, BDBM50346422, CCG-39062, NSC758641, SKF 20716, SKF-20716, 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile, AKOS030527553, API0003549, DB01608, NSC-758641, IDI1_000874, NCGC00095086-02, NCGC00095086-03, AN-18883, CAS-2622-26-6, SBI-0051867.P002, LS-105273, FT-0673633, D01485, SR-01000872777, SR-01000872777-1, BRD-K89669299-001-02-7, 1-(3-(2-cyano-10-phenothiazinyl)propyl)-4-piperidino, 10-(3-(4-hydroxypiperidino)propyl)-phenothiazine-2-carbonitril, 10-[3-(4-hydroxy-1-piperidyl)propyl]phenothiazine-2-carbonitrile, 10-[3-(4-Hydroxy-1-piperidinyl)propyl]-10H-phenothiazine-2-carbonitrile #

ID: 1316

InChIKey: LUDUHKJIKKLONS-AEXLHLMCSA-N
SMILES: CC(=O)O[C@H]1[C@@H]2CC3=C4CC(=O)O[C@H]([C@@]4(CCC3[C@@](C2=O)([C@H](C1(C)C)C(C(=O)OC)O)C)C)C5=COC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708550
synonyms found at PubChem are:
KBio3_000819, Spectrum_000602, SpecPlus_000095, Spectrum2_000249, Spectrum3_000030, Spectrum4_001311, Spectrum5_000121, BSPBio_001699, KBioGR_001741, KBioSS_001082, DivK1c_006191, SWIETENOLIDE-3-ACETATE, SPBio_000038, SCHEMBL12998447, KBio1_001135, KBio2_001082, KBio2_003650, KBio2_006218, NCGC00179075-01

ID: 1317

InChIKey: LUGFRGZVWVEDNU-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CCCCNC(=O)C3=CC4=CC=CC=C4C=C3.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6420036
synonyms found at PubChem are:
DO 897/99, SR-01000075725, Prestwick_861, AC1O4WIA, HMS1569P19, CCG-220559, SR-01000075725-5, N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide dihydrochloride

ID: 1318

InChIKey: LUHMMHZLDLBAKX-DBIGVJDZSA-N
SMILES: C[C@H]1[C@@H]2[C@H](C[C@]3(C=CC(=O)C(=C3[C@H]2OC1=O)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 65030
synonyms found at PubChem are:
Artemisin, 481-05-0, UNII-Y1R67R7XWU, Y1R67R7XWU, CHEBI:2852, (3S,3aR,4S,5aS,9bS)-4-hydroxy-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g][1]benzofuran-2,8-dione, (3S,3aR,4S,5aS,9bS)-4-hydroxy-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g]benzofuran-2,8-dione, AC1L22FQ, SCHEMBL83537, CHEMBL158124, SRI-2813, AN-45194, C09344, 481A050, 3a,5,5a,9b-Tetrahydro-4-hydroxy-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione, Naphtho(1,2-b)furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-4-hydroxy-3,5a,9-trimethyl-, (3S-(3alpha,3aalpha,4alpha,5abeta,9bbeta))-

ID: 1319

InChIKey: LUINDDOUWHRIPW-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1858
synonyms found at PubChem are:
6-CHLOROMELATONIN, 63762-74-3, 6-Cl-melatonin, 6-Cl-MLT, BRN 0410191, CHEMBL34730, N-(2-(6-Chloro-5-methoxy-1H-indol-3-yl)ethyl)acetamide, n-[2-(6-chloro-5-methoxy-1h-indol-3-yl)ethyl]acetamide, Acetamide, N-(2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl)-, N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide, SR-01000075735, melatonin, 6-Chloro, Tocris-0443, AC1Q3LDV, Lopac-C-0331, D0B8PD, AC1L1CE9, Lopac0_000178, MLS002153444, SCHEMBL677517, SCHEMBL677518, GTPL1346, CTK8F7109, ZINC57237, DTXSID30213202, CHEBI:109545, LUINDDOUWHRIPW-UHFFFAOYSA-N, MolPort-004-964-764, HMS2234G13, HMS3260D17, HMS3266A08, HMS3374G08, Tox21_500178, BDBM50043289, PDSP1_001786, PDSP2_001769, AKOS024458157, N-Acetyl-6-chloro-5-methoxytryptamine, CCG-204273, LP00178, LS-8570, NCGC00015203-01, NCGC00015203-02, NCGC00015203-03, NCGC00015203-04, NCGC00015203-05, NCGC00015203-06, NCGC00024593-01, NCGC00024593-02, NCGC00024593-03, NCGC00024593-04, NCGC00260863-01, SMR001230810, ZB002048, B6307, EU-0100178, C 0331, L000082, SR-01000075735-1, SR-01000075735-3, BRD-K34663752-001-02-6, N-[2-(5-Methoxy-6-chloroindol-3-yl)ethyl]acetamide, N-[2-(6-CHLORO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE, N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide(6-Chloromelatonin)

ID: 1320

InChIKey: LULNWZDBKTWDGK-UHFFFAOYSA-M
SMILES: CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 8246
synonyms found at PubChem are:
neostigmine bromide, 114-80-7, neo-Proserin, Eustigmin bromide, Neoserine bromide, Proserine bromide, Stigmanol bromide, Synstigmin bromide, Leostigmine bromide, Kirkstigmine bromide, Philostigmin bromide, Prostigmin, Stigmosan bromide, Prostigmin bromide, Neostigmine methyl bromide, Prostigmine bromide, Neostigmini bromidum, Synstigmini bromidum, Syntostigmin bromide, Vagostigmine bromide, Vagostigmin, 3-((Dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium bromide, Syntostigmine bromide, Synthostigmine bromide, Syntostigmin (tablet), Bromure de neostigmine, Bromuro de neostigmina, Neostigmine (Bromide), Neostigmina bromuro [DCIT], UNII-005SYP50G5, Neostigmini bromidum [INN-Latin], EINECS 204-054-8, Bromure de neostigmine [INN-French], Bromuro de neostigmina [INN-Spanish], 3-Dimethylcarbamoxyphenyl trimethyl ammonium bromide, MLS000028387, (m-Hydroxyphenyl)trimethylammonium bromide dimethylcarbamate, 3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium bromide, 3-Hydroxyphenyltrimethylammonium bromide dimethylcarbamic ester, CHEBI:179557, 005SYP50G5, SMR000058591, Vagostigmin (TN), Carbamic acid, dimethyl-, ester with (m-hydroxyphenyl)trimethylammonium bromide, DSSTox_CID_21075, DSSTox_RID_79621, DSSTox_GSID_41075, W-108598, 3-(Dimethylcarbamoyloxy)trimethylanilinium ion Bromatum, Synstigminbromid, 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium bromide, 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium bromide, 59-99-4 (Parent), AMMONIUM, (m-HYDROXYPHENYL)TRIMETHYL-, BROMIDE, DIMETHYLCARBAMATE, Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-, bromide, Benzenaminium, 3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-, bromide, Neostigmina bromuro, SR-01000000073, NCGC00163240-01, CAS-114-80-7, [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;bromide, stigmanolbromide, stigmosanbromide, Neo proserine, C12H19N2O2.Br, synstigminbromide, syntostigminbromide, vagostigminebromide, syntostigminebromide, synthostigminebromide, Prestwick_352, syntostigmin(tablet), Neostigmine bromide [INN:BAN:JAN], Prostigmin;Vagostigmin, Neostigmine bromide [USP:INN:BAN:JAN], AC1L1QKY, Opera_ID_1504, NEOSTIGIMINE BROMIDE, AC1Q1RH0, SCHEMBL41128, MLS001146913, CHEMBL54126, SPECTRUM1500428, DTXSID9041075, Neostigmine bromide (Prostigmin), HMS500I07, KS-00000YWF, MolPort-003-666-242, HMS1569M18, HMS1920P15, HMS2091H18, HMS2096M18, HMS2235J11, HMS3262D13, HMS3372E02, HMS3713M18, Pharmakon1600-01500428, Eustigmin bromide;Neoserine bromide, ACT05638, HY-B0423, Neostigmine bromide (JAN/USP/INN), Tox21_112037, Tox21_500816, AN-333, BG0265, CCG-39110, GK7491, MFCD00011795, NSC757233, s2490, AKOS015895725, Tox21_112037_1, API0003538, CS-2529, LP00816, MCULE-9726153183, NSC-757233, NCGC00015730-11, NCGC00094149-01, NCGC00094149-02, NCGC00094149-03, NCGC00094149-04, NCGC00261501-01, AK162162, LS-18446, Q562, SC-19050, MLS-0002855.P042, AB0004770, AB2000595, AX8144170, EU-0100816, FT-0083763, FT-0651572, N0358, ST24041334, ST50411544, C08197, D00995, N 2001, A803245, SR-01000000073-3, SR-01000000073-5, SR-01000000073-7, (3-Dimethylcarbamoyloxyphenyl)trimethylammonium Bromide, [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium bromide, (m-Hydroxyphenyl)trimethyl-ammonium bromide dimethylcarbamate, [3-(dimethylcarbamoyloxy)phenyl]-trimethyl-ammonium bromide, N,N-dimethyl[3-(trimethylamino)phenoxy]carboxamide, bromide, Neostigmine bromide, >=98% (HPLC and titration), powder, (3-Hydroxyphenyl)trimethylammonium Bromide Dimethyl Carbamate, [3-[dimethylamino(oxo)methoxy]phenyl]-trimethylammonium bromide, Neostigmine bromide, European Pharmacopoeia (EP) Reference Standard, Neostigmine bromide, United States Pharmacopeia (USP) Reference Standard

ID: 1321

InChIKey: LUZUAYAKZLCOCQ-BHHNFLQBSA-N
SMILES: COC\1=CC(=O)C(=C/C1=C\C=C\C2=CC=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5967872
synonyms found at PubChem are:
Obtusaquinone, 21105-15-7, (4E)-2-hydroxy-5-methoxy-4-[(E)-3-phenylprop-2-enylidene]cyclohexa-2,5-dien-1-one, 62745-67-9, AC1NZN1M, BSPBio_003216, SPECTRUM200090, CHEMBL1333653, SCHEMBL11744025, SCHEMBL17131949, OBTUSAQUINONE JURD 2066, CCG-39853, NSC269107, ZINC100068566, NSC-269107, SDCCGMLS-0066386.P001, NCGC00095826-01, NCGC00095826-02, SR-05000002504, SR-05000002504-1, 2-Hydroxy-5-methoxy-4-(3-phenyl-2-propenylidene)-2,5-cyclohexadiene-1-one, InChI=1/C16H14O3/c1-19-16-11-15(18)14(17)10-13(16)9-5-8-12-6-3-2-4-7-12/h2-11,17H,1H3/b8-5+,13-9

ID: 1322

InChIKey: LVRAKYNQYKVPIK-BSPYNPCNSA-N
SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5(CC[C@@H](C6)OC(=O)C)C)C)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 225766
synonyms found at PubChem are:
Smilagenin acetate, NSC15488, 4947-75-5, UNII-ZB6J7LT9WP, ZB6J7LT9WP, SMILAGENIN, ACETATE, (3Beta,5beta,25R)-spirostan-3-yl acetate, Isosarsasapogenin, acetate, o-Acetyltigogenin, NSC 15488, AC1L5E9Z, CHEMBL3138727, 35319-91-6, NSC40898, NSC-15488, NSC-40898, [(2R,5'R)-5'-tetramethylspiro[[?]-2,2'-tetrahydropyran]yl] acetate

ID: 1323

InChIKey: LVRAKYNQYKVPIK-UHFFFAOYSA-N
SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)OC(=O)C)C)C)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 313012
synonyms found at PubChem are:
Neotigogenin acetate, Spirostan-3-yl acetate, 4948-43-0, AC1L7MJR, Spirostan-3-yl acetate #, DTXSID60310354, LVRAKYNQYKVPIK-UHFFFAOYSA-N, MolPort-001-812-855, BBL029131, NSC226093, NSC226095, NSC226096, STL146322, AKOS005720862, MCULE-3872013495, NSC-226093, NSC-226095, NSC-226096, 5.alpha.-Spirostan-3.beta.-ol, (25S)-, Spirostan-3-ol, (3.beta.,5.alpha.,25S)-

ID: 1324

InChIKey: LVSWNSHUTPWCNF-UHFFFAOYSA-N
SMILES: CCN1C2=C(C(=O)N(C1=O)CC)NC(=N2)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1328
synonyms found at PubChem are:
1,3-Diethyl-8-phenylxanthine, DEPX, 75922-48-4, UNII-2KCV39GKGL, 2KCV39GKGL, 1,3-Dithyl-8-phenylxanthine, CHEMBL11348, 1,3-diethyl-8-phenyl-7H-purine-2,6-dione, 1,3-Diethyl-8-phenyl-3,7-dihydro-purine-2,6-dione, 1H-Purine-2,6-dione,1,3-diethyl-3,9-dihydro-8-phenyl-, Lopac-A-003, AC1Q6LCB, D07HKU, D0BD8N, AC1L1B8H, Lopac0_000125, GTPL445, 8-Phenyl-1,3-diethylxanthine, AC1Q312F, SCHEMBL1321894, BDBM81971, CTK5E2202, CAS_1328, NSC_1328, ZINC9229229, PDSP1_000323, PDSP1_000326, PDSP1_000991, PDSP2_000321, PDSP2_000324, PDSP2_000975, AKOS027378654, CCG-204220, NCGC00014999-01, NCGC00014999-02, NCGC00093616-01, EU-0100125, FT-0606658, C-48797, L001207, SR-01000075182, SR-01000075182-1, 1,3-Diethyl-8-phenyl-1H-purine-2,6(3H,7H)-dione, 1,3-Diethyl-3,9-dihydro-8-phenyl-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-phenyl-

ID: 1325

InChIKey: LWYXFDXUMVEZKS-ZVFOLQIPSA-N
SMILES: CC[C@@H](CO)NC(=O)[C@H]1CN([C@@H]2CC3=CN(C4=CC=CC(=C34)C2=C1)C)C.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281073
synonyms found at PubChem are:
Methysergide maleate, 129-49-7, Deseril-retard, Desernil bismaleate, Methysergide hydrogen maleate, Methysergide maleate salt, Methysergide dimaleate, UNII-2U7H1466GH, EINECS 204-950-9, Methysergide bimaleate, NSC 186061, Methysergide maleate [USP], 1-Methyl-D-lysergic acid butanolamide dimaleate, 2U7H1466GH, Lysergamide, N-((1-hydroxymethyl)propyl)-1-methyl-, maleate, (+)-N-((1-Hydroxymethyl)propyl)-1-methyl-D-lysergamide bimaleate, Sansert (TN), 1-(Hydroxymethyl)propylamide of 1-methyl-(+)-lysergic acid hydrogen maleate, Methysergide maleate (USP), 9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8beta-carboxamide maleate (1:1) (salt), C25H31N3O6, MLS000069364, Ergoline-8-beta-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, maleate (1:1) (salt), Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-1-(hydroxymethyl)propyl)-1,6-dimethyl-, (8beta)-, (2Z)-2-butenedioate (1:1) (salt), Ergoline-8-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, (8beta)-, (Z)-2-butenedioate (1:1) (salt), SMR000058483, Methysergide maleate [USAN], regid855989, MLS001076153, CHEBI:6894, CHEMBL1200938, Methysergide maleate salt, solid, LWYXFDXUMVEZKS-ZVFOLQIPSA-N, MolPort-003-958-638, HMS2093N13, HMS2231L15, HMS3262N07, Pharmakon1600-01505492, 29605-96-7, C21H28N3O2.C4H3O4, Tox21_500863, MFCD00083185, NSC759143, AKOS024456362, CCG-213467, LP00863, NSC-759143, NCGC00261548-01, AN-23038, LS-64362, SMR000653472, EU-0100863, M-137, D00681, SR-01000002986, SR-01000002986-2, Methysergide maleate, United States Pharmacopeia (USP) Reference Standard, [8?(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate, [8beta(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate, 1257-58-5, 32537-90-9, 52502-68-8, 87387-76-6, Ergoline-8-beta-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-,maleate (1:1) (salt), Ergoline-8beta-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, maleate (1:2) (salt), Ergoline-8beta-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, maleate (1:2) (salt) (8CI)

ID: 1326

InChIKey: LXJSJIXZOAMHTG-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC(=N2)C3=CC=C(C=C3)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1908
synonyms found at PubChem are:
8-(p-Sulfophenyl)theophylline, 8-(4-Sulfophenyl)theophylline, 80206-91-3, 8-SPT, 4-(1,3-dimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)benzenesulfonic acid, CHEMBL8488, Psp-theophylline, 8-Sulphophenyltheophylline, Lopac-A-013, 8-sulfophenyl theophylline, D09QLB, AC1L1CI3, AC1Q6X0T, Lopac0_000135, 8-(P-Sulfophenyl)Thiophylline, SCHEMBL1320226, 8-(p-Sulfophenyl)-theophylline, BDBM82023, CTK3E8290, CTK6I1750, DTXSID90230152, LXJSJIXZOAMHTG-UHFFFAOYSA-N, MolPort-006-068-692, HMS3260K12, ALBB-009371, NSC_1908, ZINC5322904, ZX-AN008233, Tox21_500135, PDSP1_000449, PDSP2_000447, STK505874, AKOS005172213, AKOS027385867, CCG-204230, LP00135, 4-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid, 4-(2,3,6,7-Tetrahydro-1,3-dimethyl-2,6-dioxo-1H-purin-8-yl)benzenesulfonic acid, Benzenesulfonic acid, 4-(2,3,6,7-tetrahydro-1,3-dimethyl-2,6-dioxo-1H-purin-8-yl)-, NCGC00015000-01, NCGC00015000-02, NCGC00015000-03, NCGC00015000-04, NCGC00015000-05, NCGC00093625-01, NCGC00093625-02, NCGC00093625-03, NCGC00260820-01, CAS_80206-91-3, LS-191126, A-013, EU-0100135, R3401, SR-01000075188, SR-01000075188-1, 4-(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)benzenesulfonic acid, 4-(1,3-dimethyl-2,6-dioxo-9H-purin-8-yl)benzenesulfonic acid, 4-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid

ID: 1327

InChIKey: LXMSZDCAJNLERA-ZHYRCANASA-N
SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5833
synonyms found at PubChem are:
spironolactone, 52-01-7, Aldactone, Spirolactone, Verospiron, Euteberol, Spiroctan, Spirolang, Verospirone, Aldactone A, Spironocompren, Melarcon, Spiresis, Spiridon, Uractone, Urusonin, Acelat, Alderon, Spirone, Xenalon, Dira, Spiro-Tablinen, Spironolactone A, spironolattone, Aquareduct, Espironolactona, Spironolactonum, Aldopur, Aldactazide, Aldace, Almatol, Deverol, Altex, Spironolattone [DCIT], Abbolactone, Veroshpiron, Aldactide, Berlactone, Duraspiron, Spiractin, SC 9420, Spironolactonum [INN-Latin], Espironolactona [INN-Spanish], Spiroctanie, Spirolakton, Diatensec, Lacalmin, Lacdene, Laractone, Nefurofan, Sagisal, Sincomen, Spiretic, Spiroderm, Spirolone, Sprioderm, Suracton, Osyrol, Supra-puren, Aldactone (TN), Verospirone Opianin, SC-9420, Spironolactone [BAN:INN:JAN], Spironolactone [INN:BAN:JAN], UNII-27O7W4T232, C24H32O4S, HSDB 3184, EINECS 200-133-6, NSC 150399, BRN 0057767, CHEMBL1393, SC 15983, CHEBI:9241, Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan), 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone, 27O7W4T232, Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-, SNL, 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone acetate, 3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone, 3-(3-Keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic acid lactone, DSSTox_CID_14186, DSSTox_RID_79120, DSSTox_GSID_34186, 17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate, S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate, Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan], Jenaspiron, Spirogamma, Spirospare, Diatense, Flumach, Frumikal, Practon, Spirobeta, Spironone, NovoSpiroton, Novo Spiroton, Novo-Spiroton, Spirono Isis, Spirono-Isis, 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone, spiro von ct, 4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate, von ct, spiro, (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan]-6'-ene-5,5'-dione, 17-alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-alpha-mercapto-3-oxo-, gamma-lactone acetate, SMR000471892, Espironolactona Alter, Spiro L.U.T., Espironolactona Mundogen, quimolactona, spirotone, Spiranolactone, Carospir, 2oax, 3vhu, Berlactone (TN), CAS-52-01-7, Verospiron (TN), Spiractin (TN), Spirotone (TN), Aldactazide (TN), NCGC00015948-02, 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alpha.-yl)propionic acid lactone, 7-.alpha.-(acetylthio)-17-.alpha.-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, .gamma.-lactone, CPD000471892, S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate, S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate, Spironolactone [USP:INN:BAN:JAN], SC9420, Novo-Spiroton (TN), Prestwick0_000128, Prestwick1_000128, Prestwick2_000128, Prestwick3_000128, D0EP0C, AC1L1L8Q, Dexo Brand of Spironolactone, BIDD:PXR0071, SCHEMBL20939, BSPBio_000176, 4-18-00-01601 (Beilstein Handbook Reference), Alter Brand of Spironolactone, MLS001074672, MLS001333253, MLS001333254, MLS002153245, MLS002207058, MLS002548846, Roche Brand of Spironolactone, Cardel Brand of Spironolactone, Pfizer Brand of Spironolactone, Searle Brand of Spironolactone, SPBio_002115, Worwag Brand of Spironolactone, BPBio1_000194, GTPL2875, Alpharma Brand of Spironolactone, DTXSID6034186, Hormosan Brand of Spironolactone, Mundogen Brand of Spironolactone, betapharm Brand of Spironolactone, Ashbourne Brand of Spironolactone, Azupharma Brand of Spironolactone, Generosan Brand of Spironolactone, Jenapharm Brand of Spironolactone, Novopharm Brand of Spironolactone, Alphapharm Brand of Spironolactone, LXMSZDCAJNLERA-ZHYRCANASA-N, MolPort-033-355-721, Pharmafrid Brand of Spironolactone, Spironolactone (JP15/USP/INN), Spironolactone (JP17/USP/INN), HMS1568I18, HMS2090N21, HMS2095I18, HMS2236E06, HMS3259G11, HMS3712I18, Merck dura Brand of Spironolactone, ACT02596, HY-B0561, KS-00000FA6, Spironolactone, 97.0-103.0%, ZINC3861599, Tox21_113047, Tox21_302154, BDBM50228080, MFCD00082250, NSC150399, s4054, AKOS015896401, AC-4214, CCG-220128, CS-2670, ct Arzneimittel Brand of Spironolactone, ct-Arzneimittel Brand of Spironolactone, DB00421, KS-5234, Mayoly-Spindler Brand of Spironolactone, MCULE-4394091100, NC00482, NSC-150399, NCGC00164397-01, NCGC00164397-02, NCGC00164397-03, NCGC00164397-05, NCGC00255229-01, BC204094, H490, SC-15112, Spironolactone 1.0 mg/ml in Acetonitrile, AB1009415, LS-118614, AB00513806, LT00772287, S0260, 7080-EP2269989A1, 7080-EP2270011A1, 7080-EP2272841A1, 7080-EP2295406A1, 7080-EP2298772A1, 7080-EP2298776A1, 7080-EP2301936A1, 7080-EP2308562A2, 7080-EP2308839A1, C07310, D00443, EN300-123035, AB01275520-01, AB01275520_02, 082S250, SR-01000765419, SR-05000000452, I06-1970, Q-201737, SR-01000765419-2, SR-05000000452-2, BRD-K90027355-001-03-4, BRD-K90027355-001-19-0, Z1551900341, Spironolactone, European Pharmacopoeia (EP) Reference Standard, WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ, 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone acetate, Spironolactone, United States Pharmacopeia (USP) Reference Standard, 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, acetate, Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, (7.alpha.,17.alpha.)-, (7?,17?)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid ?-lactone, 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone, 7alpha-(Acetylthio)-17alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone, Spironolactone for system suitability, European Pharmacopoeia (EP) Reference Standard, (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadecan]-6'-ene-5,5'-dione, 1050678-93-7, 17-HYDROXY-7ALPHA-MERCAPTO-3-OXO-17ALPHA-PREGN-4-ENE-21- CARBOXYLIC ACID, GAMMA-LACTONE ACETATE, 2'',15''-dimethyl-5,5''-dioxo-(9''R)-spiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate, 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate, 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate(Spiranolactone), 4-Pregnen-21-oic acid-17|A-ol-3-one-7|A-thiol |A-lactone 7-acetate; 7|A-(Acetylthio)-17|A-hydroxy-3-oxopregn-4-ene-21-carboxylic acid |A-lactone, 496916-40-6, 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI), S-(2''R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5''-dioxo-1,2,3,4'',5'',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3''H-spiro[cyclopenta[a]phenanthrene-17,2''-furan]-7-yl ethanethioate, Spiro(17H-cyclopenta(a)phenanthrene-17,2'(5'H)-furan), pregn-4-ene-21-carboxylic acid deriv

ID: 1328

InChIKey: LXOHMGALVZOYRF-BTJKTKAUSA-N
SMILES: C1CN(CCN1)C2=NC3=C(C=C2)C=C(C=C3)[N+](=O)[O-].C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957672
synonyms found at PubChem are:
6-Nitroquipazine maleate salt, Quipazine, 6-nitro-, maleate, UNII-ORQ6D36T5V, ORQ6D36T5V, 129047-05-8, 6-nitroquipazine maleate, 6-NITRO-2-(1-PIPERAZINYL)-QUINOLINE MALEATE, Du-24565 maleate, 6-Nitro-2-(1-piperazinyl)quinoline maleate salt, EU-0101010, MLS000860053, SCHEMBL4266383, CHEMBL1256913, DTXSID8042557, NOCAS_42557, HMS2232E16, HMS3263I21, Tox21_501010, 6-Nitroquipazine maleate salt, solid, Quinoline, 6-nitro-2-(1-piperazinyl)-, (Z)-2-butenedioate (1:1), AKOS030558633, CCG-222314, LP01010, NCGC00094303-01, NCGC00261695-01, SMR000326911, 6-Nitro-2-(1-piperzinyl)-quinoline maleate, Q-109, SR-01000075570, SR-01000075570-1, 6-nitro-2-(piperazin-1-yl)quinoline (2Z)-but-2-enedioate

ID: 1329

InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
SMILES: N.N.[Cl-].[Cl-].[Pt+2]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 84691
synonyms found at PubChem are:
dichloroplatinum diammoniate, 14283-03-5, AC1L37ZV, AC1Q4U6G, UNII-Q20Q21Q62J, CCRIS 5161, Diamminedichloroplatinum (trans), HSDB 3940, azane; platinum(2+); dichloride, DTXSID50275807, MolPort-019-879-028, (SP-4-2)-Diaminedichloroplatinum, Q20Q21Q62J, trans-Diamminedichloroplatinum (II), trans-Dichlorodiammineplatinum (II), trans-Platinum(II)diamminedichloride, EINECS 238-980-9, EINECS 247-419-7, Platinum, diamminedichloro-, trans-, cis-Platinum(II) diammine dichloride, AKOS015853703, NSC 131558, NSC 241517, RL02014, Platinum (II), diamminedichloro-, trans-, Platinum, diamminedichloro-, (SP-4-1)-, TRANS-DICHLORODIAMMINE PLATINUM(II), LS-117696, D3371, S-7707, J-009324, Lopac-P-4394, AOB5244, Tox21_500918, NCGC00015812-01, NCGC00094229-01, NCGC00094229-02, NCGC00162292-01, NCGC00162292-02, NCGC00261603-01, 14913-33-8, trans-Dichlorodiamineplatinum(II), azane; dichloroplatinum, H6Cl2N2Pt, SR-05000001586, IA call, Cisplatin,(S), AC1NUSPB, DDP-H, PLATINOL (TN), AC1NWAU8, Cl.2H3N.Pt, platinum(II) chloride diamine, SPECTRUM1502107, Cisplatin (JP17/USP/INN), HMS502M12, MolPort-001-794-642, PLATINUM DIAMINO DICHLORIDE, Trans-Platinum diammine dichloride, E(3)AE degrees +/-(2) not, HMS1921J18, HMS2092D04, BCP01792, BCP18182, KS-00000VH3, 7433AA, CCG-39901, trans-Platinum(II)diammine dichloride, AKOS005137969, CS-1122, NSC-119875, NCGC00094962-01, NCGC00094962-02, NCGC00094962-03, H878, HY-17394, ST24050219, C06911, D00275, J90019, cis-Diammineplatinum(II) dichloride, crystalline, 913C338, SR-01000076254, SR-01000076254-1, SR-05000001586-1, SR-05000001586-3, I14-18358, I14-45043, Cisplatin, European Pharmacopoeia (EP) Reference Standard, Cisplatin, United States Pharmacopeia (USP) Reference Standard, cis-Diamineplatinum(II) dichloride, >=99.9% trace metals basis, Cisplatin impurity A, European Pharmacopoeia (EP) Reference Standard, Transplatin, United States Pharmacopeia (USP) Reference Standard, Cisplatin, Pharmaceutical Secondary Standard; Certified Reference Material, E(3)- paragraph signthornAE paragraph signthorn degrees +/->>u(2) not(II), E(3)E(1/2)- paragraph signthorn degrees . paragraph signthornAE(2) not, . E(1/2)- paragraph signthorn degrees +/->>u paragraph signthornAE>> (2) not(II)

ID: 1330

InChIKey: LYUZYPKZQDYMEE-YRCPKEQFSA-N
SMILES: C/C=C(/C)\C(=O)O[C@H]1[C@H](C(OC2=C1C3=C(C=C2)C=CC(=O)O3)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281425
synonyms found at PubChem are:
Pteryxin, 13161-75-6, Pterixin, AC1NQYG8, MLS002472948, CHEBI:8632, HMS2205E19, (+)-Pteryxin, [(9R,10R)-9-acetoxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] (Z)-2-methylbut-2-enoate, [(9R,10R)-9-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] (Z)-2-methylbut-2-enoate, Bio-0315, UNII-C1G8A9744Z, CHEMBL1884860, SCHEMBL14511558, MolPort-002-526-070, C1G8A9744Z, BCP10886, ZINC4081606, AKOS015969719, SMR001397056, N2037, C09307, 2-Butenoic acid, 2-methyl-, 9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3,4-b')dipyran-10-yl ester, (9R-(9alpha,10alpha(Z)))-, 2-Butenoic acid, 2-methyl-, 9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3- ,4-b')dipyran-10-yl ester, (9R-(9alpha,10alpha(Z)))-

ID: 1331

InChIKey: LYZGJWXNOGIVQA-UHFFFAOYSA-M
SMILES: CCCC(C)C1(C(=O)NC(=NC1=O)[S-])CC=C.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9557
synonyms found at PubChem are:
Thiamylal sodium, Surital sodium, Sodium thiamylal, Thiomylal sodium, Thioseconal sodium, Surital sodium salt, Thiamylal sodium salt, EINECS 206-415-5, 5-Allyl-5-(1-methylbutyl)-2-thiobarbiturate sodium, Sodium 5-allyl-5-(1-methylbutyl)-2-thiobarbiturate, NCGC00095772-01, 5-Allyl-5-(1-methylbutyl)-2-thio-barbituric acid sodium salt, Surital (TN), 337-47-3, 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid, sodium derivative, BARBITURIC ACID, 5-ALLYL-5-(1-METHYLBUTYL)-2-THIO-, SODIUM SALT, 4,6-(1H,5H)-Pyrimidinedione, dihydro-5-(1-methylbutyl)-5-(2-propenyl)-2-thioxo-, monosodium salt, Surital sodium deriv., Thiamylal sodium [USP:JAN], Thiamylal sodium [USAN:JAN], Surital sodium deriv, Thiamylal sodium (JP17), DSSTox_CID_25988, DSSTox_RID_81275, DSSTox_GSID_45988, SCHEMBL34746, C12H17N2O2S.Na, SPECTRUM1900002, CHEBI:9537, CHEMBL1201065, DTXSID3045988, HMS503E21, 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid, sodium salt, HMS2094G05, Tox21_111517, CCG-213640, NCGC00095772-02, 4,6(1H,5H)-Pyrimidinedione, dihydro-5-(1-methylbutyl)-5-(2-propenyl)-2-thioxo-, monosodium salt, CAS-337-47-3, LS-23765, D00713, AKOS027381591

ID: 1332

InChIKey: LZDNBBYBDGBADK-UHFFFAOYSA-N
SMILES: CC(C)C(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3360287
synonyms found at PubChem are:
valyltryptophan, VW dipeptide, Valyl-Tryptophan, V-W Dipeptide, AC1MNXS1, Valine Tryptophan dipeptide, Valine-Tryptophan dipeptide, SCHEMBL150532, CHEMBL1495428, LZDNBBYBDGBADK-UHFFFAOYSA-N, VZ34087, NCGC00095886-01, 2-(2-amino-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid, 2-[(2-amino-3-methylbutanoyl)amino]-3-(1H-indol-3-yl)propanoic acid, VW

ID: 1333

InChIKey: LZFATBMLSYHRTC-WXXKFALUSA-N
SMILES: C1CC1C(C2CC2)NC3=NCCO3.C1CC1C(C2CC2)NC3=NCCO3.C(=C/C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 45073450
synonyms found at PubChem are:
207572-68-7, Rilmenidene hemifumarate salt, Oxaminozoline hemifumarate salt, N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine hemifumarate salt, fumaric acid; bis(hyperium), butenedioic acid; bis(hyperium), LZFATBMLSYHRTC-WXXKFALUSA-N, MolPort-003-983-672, HMS1571E05, Rilmenidine hemifumarate salt, solid, BN0438, MFCD09878261, AKOS024458651, RT-015408, 2-[N-(Dicyclopropylmethyl)amino]oxazoline hemifumarate

ID: 1334

InChIKey: LZJRNLRASBVRRX-ZDUSSCGKSA-N
SMILES: CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)O)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10154
synonyms found at PubChem are:
Boldine, 476-70-0, Uniboldina, Boldin, (S)-Boldine, Boldine chloroform, (+)-Boldine, NSC 65689, UNII-8I91GE2769, (S)-(+)-Boldine, EINECS 207-509-9, 1,10-Dimethoxy-2,9-dihydroxyaporphine, BRN 0094036, CHEBI:3148, CHEMBL388342, 1,10-Dimethoxy-6a-alpha-aporphine-2,9-diol, LZJRNLRASBVRRX-ZDUSSCGKSA-N, 8I91GE2769, (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol, 4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)-, 4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-, 6a-alpha-APORPHINE-2,9-DIOL, 1,10-DIMETHOXY-, (S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol, 2,9-Dihydroxy-1,10-dimethoxyaporphine, (+)-(S)-Boldine, Aprophine alkaloid, 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-, Prestwick_46, AC1L1ULW, Prestwick3_000600, Boldine, analytical standard, BSPBio_000480, 5-21-06-00118 (Beilstein Handbook Reference), cid_10154, MLS002153899, SCHEMBL177550, AC1Q469J, BPBio1_000528, cid_248507, 5,6,6a,7-Tetrahydro-1,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-2,9-diol, MolPort-001-728-137, HMS2096H22, HMS2235B04, ZINC135449, TNP00245, BDBM50202318, Boldine, analytical reference material, AKOS015912953, API0001747, CCG-208461, MCULE-6617451493, NCGC00016454-01, NCGC00016454-02, NCGC00017314-01, NCGC00179547-01, AJ-12267, AN-45156, AS-17759, CAS-476-70-0, LS-21477, SMR001233248, 6aalpha-Aporphine-2,9-diol, 1,10-dimethoxy-, C09365, 1,10-Dimethoxy-6a-.alpha.-aporphine-2,9-diol, 476B700, 6a.alpha.-Aporphine-2,9-diol, 1,10-dimethoxy-, 6aalpha-Aporphine-2,9-diol, 1,10-dimethoxy- (8CI), BRD-K03440695-001-02-6, I14-48402, Boldine, European Pharmacopoeia (EP) Reference Standard, 1,10-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol, (S)-, (9S)-4,16-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2,4,6,13,15-hexaene-5,15-diol

ID: 1335

InChIKey: LZMHWZHOZLVYDL-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=CC3=NOC(=O)N23

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1456
synonyms found at PubChem are:
1h-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, 41443-28-1, ODQ, [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, UNII-S57V2NMV38, S57V2NMV38, 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one, 1H-[1,2,4]oxadiazolo-[4,3,a]quinoxalin-1-one, SR-01000075519, 1-H-[1,2,4]Oxadiazolo-[4,3,2]quinoxalin-1-ine, 1H-(1,2,4)Oxadiazolo-(4,3,A)quinoxalin-1-one, 1H-ODQ, Tocris-0880, AC1L1BIQ, Lopac-O-3636, D0R3FS, AC1Q6H5T, Lopac0_000953, SCHEMBL210817, CHEMBL598952, GTPL5234, DTXSID2036796, CHEBI:91215, CTK1D6485, MolPort-003-959-081, HMS3262P08, HMS3266N10, HMS3649K18, BCP06748, KS-000013GE, ZINC2569341, Tox21_500953, 1963AH, BS0137, GL1507, MFCD00792620, AKOS024458675, AN-1844, CCG-205034, FCH1122307, LP00953, NNC07-9008, ACM41443281, NCGC00015770-01, NCGC00015770-02, NCGC00015770-03, NCGC00015770-04, NCGC00015770-05, NCGC00024841-01, NCGC00024841-02, NCGC00024841-03, NCGC00261638-01, AC-26876, AS-53689, KB-12217, LS-99342, B6486, EU-0100953, FT-0673321, O0400, ST50825268, O 3636, SR-01000075519-1, SR-01000075519-3, SR-01000075519-6, 1h-(1,2,4)-oxadiazolo-(4,3-a)-quinoxalin-1-one, BRD-K26015241-001-01-0, I14-93346, 10-hydro-1,2,4-oxadiazolino[4,3-a]quinoxalin-1-one, 1H-[1,2,4]OXADIAZOLE[4,3-A]QUINOXALIN-1-ONE, 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one (9CI), 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, powder, 1H-[1,2,4]OXADIAZOLO[4,3-a]-QUINOXALIN-1-ONE

ID: 1336

InChIKey: LZMRVYPPUVMKOI-UHFFFAOYSA-N
SMILES: CN1C=NC2=C1N=CN=C2NC3CCCC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4401
synonyms found at PubChem are:
N6-Cyclopentyl-9-methyladenine, N(6)-Cyclopentyl-9-methyladenine, N-0840, 109292-91-3, CHEMBL48278, 9H-Purin-6-amine,N-cyclopentyl-9-methyl-, Cyclopentyl-(9-methyl-9H-purin-6-yl)-amine, n-cyclopentyl-9-methyl-9h-purin-6-amine, Lopac-N-154, AC1Q4XZM, D01EHP, Lopac0_000921, AC1L1I31, SCHEMBL1322040, ZINC5203, DTXSID60148871, LZMRVYPPUVMKOI-UHFFFAOYSA-N, N6 -Cyclopentyl-9-Methyl Adenine, BDBM50009698, N-cyclopentyl-9-methylpurin-6-amine, n0840, CCG-205003, NCGC00015717-01, NCGC00015717-02, NCGC00015717-03, NCGC00015717-04, NCGC00094232-01, NCGC00094232-02, NCGC00094232-03, LS-193781, 9H-Purin-6-amine, N-cyclopentyl-9-methyl-, EU-0100921, N-154, L005913, SR-01000075226, SR-01000075226-1

ID: 1337

InChIKey: LZNWYQJJBLGYLT-UHFFFAOYSA-N
SMILES: CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 54677971
synonyms found at PubChem are:
tenoxicam, 59804-37-4, Mobiflex, Tilcotil, Tenoxicamum, Liman, Tenoxicamum [INN-Latin], Apo-Tenoxicam, Novo-Tenoxicam, Ro 12-0068, Tilcotil (TN), UNII-Z1R9N0A399, CCRIS 5264, Tenoxicam [USAN:BAN:INN:JAN], Ro 12-0068/000, BRN 0572193, Ro-12-0068, Tenoxicam (JAN/USAN/INN), 4-Hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide, MLS000069830, CHEBI:32192, C13H11N3O4S2, LZNWYQJJBLGYLT-UHFFFAOYSA-N, Z1R9N0A399, 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, Ro-120068, NCGC00016889-01, SMR000058865, CAS-59804-37-4, (3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one, 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide, 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide, DSSTox_CID_25486, DSSTox_RID_80909, DSSTox_GSID_45486, 4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE, Alganex, Artriunic, Octiveran, Reutenox, Rexalgan, 3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one, (3E)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one, SR-01000721894, (4-hydroxy-2-methyl-1,1-dioxothiopheno[2,3-e]1,2-thiazin-3-yl)-N-(2-pyridyl)ca rboxamide, 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide, Tenoxicam [USAN:INN:BAN:JAN], Mobiflex (TN), Tenoxicam, NSAID, 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide, Mobiflex, Tenoxicam, Prestwick_849, Tenoxicam(Mobiflex), Spectrum_001430, Novag brand of tenoxicam, Roche brand of tenoxicam, AC1NQZN7, AC1NSM4C, Apotex brand of tenoxicam, Opera_ID_1757, Prestwick0_000527, Prestwick1_000527, Prestwick2_000527, Prestwick3_000527, Solvay brand of tenoxicam, Spectrum2_001080, Spectrum3_001563, Spectrum4_000731, Spectrum5_001615, D0I6IB, AC1L1K9K, Novopharm brand of tenoxicam, SCHEMBL25343, SCHEMBL25344, BSPBio_000513, BSPBio_003066, KBioGR_001022, KBioSS_001910, MLS001074071, MLS006011432, BIDD:GT0650, DivK1c_000252, SPECTRUM1503142, SPBio_001100, SPBio_002434, BPBio1_000565, CHEMBL302795, CHEMBL3188633, DTXSID8045486, SCHEMBL13448847, BCBcMAP01_000251, BDBM92332, CTK7I2701, HMS500M14, KBio1_000252, KBio2_001910, KBio2_004478, KBio2_007046, KBio3_002566, MolPort-000-884-690, NINDS_000252, HMS1569J15, HMS1923I15, HMS2090P19, HMS2092L20, HMS2096J15, HMS2232K23, HMS3370L01, HMS3656O10, HMS3713J15, Pharmakon1600-01503142, BCP03624, HY-B0440, KS-000010UB, ZX-AT018824, Tox21_110666, BBL028173, BG0331, CCG-40126, MFCD00083502, NSC758397, s2512, SBB056362, STK637103, ZINC12503102, ZINC40884328, AKOS000282084, AKOS026750148, Tox21_110666_1, ZINC100006429, AC-4526, CS-2546, DB00469, KS-1313, MCULE-4636246417, NSC-758397, IDI1_000252, SMP1_000040, NCGC00016889-02, NCGC00016889-03, NCGC00016889-05, NCGC00016889-06, NCGC00095260-01, NCGC00095260-02, AN-11871, BC205092, SC-13535, BCP0726000170, SBI-0051780.P002, AB0012300, AB2000615, KB-269204, LS-152556, Ro-120068000, FT-0659572, ST50950119, D01767, AB00052322-11, AB00052322_12, AB00052322_13, 804T374, A832479, C-20248, I02-0320, SR-01000721894-2, SR-01000721894-4, Tenoxicam, British Pharmacopoeia (BP) Reference Standard, Tenoxicam, European Pharmacopoeia (EP) Reference Standard, 3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-thieno[2,3-e]thiazin-4-one, 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide1,1-dioxide, N-(2-pyridyl)-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, (3Z)-2-methyl-1,1-bis(oxidanylidene)-3-[oxidanyl-(pyridin-2-ylamino)methylidene]thieno[2,3-e][1,2]thiazin-4-one, (3Z)-3-[hydroxy-(2-pyridinylamino)methylidene]-2-methyl-1,1-dioxo-4-thieno[2,3-e]thiazinone, (Z)-3-(hydroxy(pyridin-2-ylamino)methylene)-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide, 3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide, 4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno-[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, 4-hydroxy-2-methyl-n-pyridin-2-yl-2h-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide, 4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (Tenoxicam)

ID: 1338

InChIKey: LZUNYTZRKSOHRX-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C3=C(CO2)OC4=CC5=C(CCO5)C=C4C3=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4285596
synonyms found at PubChem are:
AC1N7VFA, DIHYDRODEHYDROEROSONE

ID: 1339

InChIKey: LZZYPRNAOMGNLH-UHFFFAOYSA-M
SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5974
synonyms found at PubChem are:
Cetrimonium bromide, 57-09-0, Hexadecyltrimethylammonium bromide, Cetyltrimethylammonium bromide, CTAB, Centimide, CETAB, Bromat, Ctmab, Cee dee, Cetavlon, Trimethylcetylammonium bromide, Cetyl trimethyl ammonium bromide, Cetaflon, Lauroseptol, Lissolamine, Pollacid, Quamonium, Suticide, Cetarol, Micol, Cetrimide bp, Lissolamine A, Cetavlon bromide, Hexadecyl trimethyl ammonium bromide, Lissolamin V, Cycloton V, Cirrasol OD, Acetoquat CTAB, Softex KW, Cetrimonii bromidum, N-Cetyltrimethylammonium bromide, Bromuro de cetrimonio, Cetrimida, Cetrimidum, Trimethylhexadecylammonium bromide, Mical, Bromure de cetrimonium, Cirrasol-OD, N-HEXADECYLTRIMETHYLAMMONIUM BROMIDE, Hexadecyltrimethylammoniumbromide, N,N,N-trimethylhexadecan-1-aminium bromide, (1-Hexadecyl)trimethylammonium bromide, Palmityltrimethyl ammonium bromide, Bromat (VAN), CTABR, Micol (VAN), Cetrimonium (bromide), Caswell No. 167, N,N,N-Trimethyl-1-hexadecanaminium bromide, N,N,N-Trimethylcetylammonium bromide, Lissolamine V (VAN), Cetavlex, Cradocap, Zetrimid, Palmityltrimethylammonium bromide, UNII-L64N7M9BWR, Cetrimonio bromuro [DCIT], N-Hexadecyl-N,N,N-trimethylammonium bromide, 1-Hexadecanaminium, N,N,N-trimethyl-, bromide, CHEBI:3567, Cetrimonii bromidum [INN-Latin], 1-Hexadecyltrimethylammonium bromide, EINECS 200-311-3, Bromure de cetrimonium [INN-French], Bromuro de cetrimonio [INN-Spanish], NSC 32927, EPA Pesticide Chemical Code 069117, L64N7M9BWR, AI3-12209, CHEMBL307346, hexadecyltrimethylamine, bromide, hexadecyl(trimethyl)azanium bromide, hexadecyl(trimethyl)ammonium bromide, Hexadecyl-trimethyl-ammonium; bromide, Ammonium, hexadecyltrimethyl-, bromide, NCGC00164283-01, DSSTox_CID_17028, DSSTox_RID_79297, DSSTox_GSID_37028, Q-200821, 1-Hexadecanaminium, N,N,N-trimethyl-, bromide (1:1), Cetrimide [INN:BAN:JAN], Cetrimonio bromuro, CAS-57-09-0, 6899-10-1 (Parent), SR-05000001830, Cetrimonium bromide [INN], cetyltrimethylammoniumbromide, C19H42N.Br, Cetrimid, Lissolamine V, Hexadecanyltrimethylammonium bromide, Cetrimonium bromide [INN:BAN:NF], Epitope ID:116869, EC 200-311-3, AC1L1LJ0, C19H42BrN, SCHEMBL4377, ACMC-1AP33, Cetrimonium Bromide (CTAB), Zephirol Related Compound 5, aaxOEy(1/4)xi section sign, KSC494A9T, cetyl trimethylammonium bromide, cetyltrimethyl ammonium bromide, cetyltrimethyl-ammonium bromide, SPECTRUM1503200, Cetrimonium bromide (NF/INN), cetyl trimethyl-ammonium bromide, cetyl-trimethyl-ammonium bromide, hexadecyltrimethylazanium bromide, DTXSID5037028, CTK3J4099, HMS500K11, ABLOCK AB-12-0440, hexadecyl-trimethylammonium bromide, LZZYPRNAOMGNLH-UHFFFAOYSA-M, MolPort-003-666-454, N,N-Trimethylcetylammonium bromide, HMS1922G21, HMS2092L22, HMS3652J19, Pharmakon1600-01503200, hexadecyl-trimethyl ammonium bromide, HY-B1260, NSC32927, Tox21_112096, Tox21_300853, ANW-32635, CCG-39968, GD0341, MFCD00011772, NSC-32927, NSC758401, s4242, SBB008910, ScintiGest™ Tissue Solubilizer, STL477543, AKOS015915119, Tox21_112096_1, CS-4893, JC10039, MCULE-7452998571, NSC-758401, RL04155, RONACARE(R) CETRIMONIUM BROMIDE, RTR-019965, Hexadecyltrimethylammonium bromide, 99%, KS-000000T0, N,N-Trimethyl-1-hexadecanaminium bromide, NCGC00095012-01, NCGC00095012-02, NCGC00164283-07, NCGC00254756-01, AK150860, AN-16018, AS-11739, BC203060, BP-30064, CC-29268, LS-18065, LS-52812, N-Hexadecyl-N,N-trimethylammonium bromide, Q564, SC-18466, WLN: 16K1&1&1 &Q &E, Hexadecyltrimethylammonium bromide, >=98%, 1-Hexadecanaminium,N,N-trimethyl-, bromide, AB1002025, DB-050366, KB-254223, TR-019965, aa>> E(R)AuIe>>uEy(1/4)xi section sign, FT-0652251, FT-0655369, ST24048154, ST51046347, C11275, D03454, Hexadecyltrimethylammonium bromide, 98% 100g, Hexadecyltrimethylammonium bromide, AR, >=99%, N-CETYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE, (3/4) A IeEy(1/4)x>>uaa>> i section sign, A831309, C-34972, (Dodecyl hexadecyl tetradecyl)trimethylammoniumbromid, HEXADECANAMINIUM, N,N,N-TRIMETHYL-, BROMIDE, Hexadecyltrimethylammonium bromide, >=96.0% (AT), Hexadecyltrimethylammonium bromide, BioXtra, >=99%, I14-6790, SR-05000001830-1, SR-05000001830-3, Hexadecyltrimethylammonium bromide, analytical standard, UNII-24QSH2NL8N component LZZYPRNAOMGNLH-UHFFFAOYSA-M, Hexadecyltrimethylammonium bromide, BioUltra, >=99.0% (AT), Hexadecyltrimethylammonium bromide, for ion pair chromatography, Hexadecyltrimethylammonium bromide, for molecular biology, >=99%, Hexadecyltrimethylammonium bromide, Vetec(TM) reagent grade, 96%, Cetrimonium bromide, United States Pharmacopeia (USP) Reference Standard, Cetrimonium bromide; Cetyltrimethylammonium bromide; CTAB; Palmityltrimethylammonium bromide, Hexadecyltrimethylammonium bromide, BioUltra, for molecular biology, >=99.0% (AT), Hexadecyltrimethylammonium bromide, puriss. p.a., matrix substance for MALDI-MS, 104302-76-3, 108779-80-2, 12294-25-6, 69217-35-2, 79631-76-8, Hexadecyltrimethylammonium bromide, PharmaGrade, USP/NF, Manufactured under appropriate controls for pharma or biopharmaceutical production., Trimethyltetradecylammoniumbromid-Dodecyltrimethylammoniumbromid-Hexadecyltrimethylammoniumbromid

ID: 1340

InChIKey: MAASHDQFQDDECQ-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 262093
synonyms found at PubChem are:
NSC 95397, 93718-83-3, 2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, NSC-95397, NSC95397, 2,3-bis(2-hydroxyethylsulfanyl)naphthalene-1,4-dione, MLS002153403, CHEMBL429095, SMR001230781, SR-01000075930, 1,4-Naphthalenedione, 2,3-bis[(2-hydroxyethyl)thio]-, Tocris-1547, AC1Q6JAF, Lopac-N-1786, D0J1KH, Lopac0_000629, BSPBio_001155, KBioGR_000495, KBioSS_000495, AC1L66Q4, cid_262093, SCHEMBL2530685, CHEBI:93193, CTK3I8111, KBio2_000495, KBio2_003063, KBio2_005631, KBio3_000909, KBio3_000910, DTXSID10294236, MolPort-003-958-936, Bio2_000408, Bio2_000888, C14H14O4S2, HMS1362I17, HMS1792I17, HMS1990I17, HMS3261N20, HMS3268C19, HMS3403I17, ZINC1615742, Tox21_500629, 3685AF, BDBM50208827, BS0132, EI-309, AKOS015856811, 1, 2,3-bis[(2-hydroxyethyl)thio]-, CCG-204717, LP00629, IDI1_002163, KS-0000184P, NCGC00015729-01, NCGC00015729-02, NCGC00015729-03, NCGC00015729-04, NCGC00015729-05, NCGC00015729-06, NCGC00015729-07, NCGC00015729-08, NCGC00025211-01, NCGC00025211-02, NCGC00025211-03, NCGC00025211-04, NCGC00025211-05, NCGC00261314-01, KB-62467, NCI60_042120, N1786 (NSC95397), TR-029556, TR-031249, B6784, BB 0237270, EU-0100629, FT-0677483, NSC 95397, >=97% (HPLC), N 1786, 2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione, 2,3-bis[(2-Hydroxyethyl)thio]-1,4-naphthoquinone, 2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone, I09-2923, SR-01000075930-1, SR-01000075930-3, SR-01000075930-7, SR-01000075930-8, BRD-K68143200-001-02-6, 2,3-Bis-(2-hydroxy-ethylsulfanyl)-[1,4]naphthoquinone, safrole,4-allyl-1,2-methylenedioxybenzene,shikimol,1-allyl-3,4-methylene dioxybenzene,5-(2-propenyl)-1,3-benzodioxole,allylcatechol methylene ether,allyldioxybenzene methylene ether,m-allylpyrocatehin methylene ether

ID: 1341

InChIKey: MAEIEVLCKWDQJH-UHFFFAOYSA-N
SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2471
synonyms found at PubChem are:
bumetanide, 28395-03-1, 3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, Bumex, Burinex, Fordiuran, Lunetoron, Fontego, Segurex, Bumetanida, Bumetanidum, Ro 10-6338, Aquazone, Bumethanide, Burine, Butinat, Cambiex, Diurama, Yurinex, Bumetanidum [INN-Latin], Bumetanida [INN-Spanish], Lixil-Leo, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid, Lixil, PF 1593, Benzoic acid, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-, Bufenox, UNII-0Y2S3XUQ5H, Bumex (TN), Bumetanide [USAN:BAN:INN:JAN], EINECS 249-004-6, PF-1593, BRN 2185351, 0Y2S3XUQ5H, MLS000028457, CHEBI:3213, Bumetanide (Ro 10-6338), BENZOIC ACID, 3-(BUTYLAMINO)-4-PHENOXY-5-SULFAMOYL-, C17H20N2O5S, MAEIEVLCKWDQJH-UHFFFAOYSA-N, 3-(butylamino)-4-phenoxy-5-sulfamoyl-benzoic acid, NCGC00015149-02, SMR000058418, CAS-28395-03-1, DSSTox_CID_2699, B 3023, 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid, DSSTox_RID_76695, 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid, DSSTox_GSID_22699, 3-(aminosulfonyl)-5-(butylamino)-4-(phenyloxy)benzoic acid, Bumedyl, Drenural, Miccil, SR-01000003062, Bumetanide (JP15/USP), Bumex, Bumetanide, Prestwick_679, PF1593, Bumetanide Leo Brand, Bumetanide [USAN:USP:INN:BAN:JAN], Bumetanide Roche Brand, Spectrum_001317, Bumetanide, >=98%, Leo Brand of Bumetanide, Bumetanide Atlantis Brand, Opera_ID_1734, Prestwick0_000276, Prestwick1_000276, Prestwick2_000276, Prestwick3_000276, Spectrum2_001050, Spectrum3_001481, Spectrum4_000030, Spectrum5_001212, Lopac-B-3023, Roche Brand of Bumetanide, Bumetanide Farmacusi Brand, Bumetanide Grossmann Brand, Bumetanide Senosiain Brand, D0R7HO, AC1L1DR5, cid_2471, Bumetanide AstraZeneca Brand, Atlantis Brand of Bumetanide, CHEMBL1072, Lopac0_000162, SCHEMBL27525, BSPBio_000152, BSPBio_001508, BSPBio_003061, KBioGR_000228, KBioGR_000439, KBioSS_000228, KBioSS_001797, Farmacusi Brand of Bumetanide, Grossmann Brand of Bumetanide, MLS001148265, Senosiain Brand of Bumetanide, DivK1c_000034, SPECTRUM1502004, SPBio_000980, SPBio_002371, AstraZeneca Brand of Bumetanide, BPBio1_000168, Bumetanide (JP15/USP/INN), Bumetanide (JP17/USP/INN), GTPL4837, DTXSID5022699, BDBM25903, CTK8B4560, HMS500B16, KBio1_000034, KBio2_000228, KBio2_001797, KBio2_002796, KBio2_004365, KBio2_005364, KBio2_006933, KBio3_000455, KBio3_000456, KBio3_002561, MolPort-003-666-390, NINDS_000034, Bio1_000421, Bio1_000910, Bio1_001399, Bio2_000228, Bio2_000708, HMS1361L10, HMS1568H14, HMS1791L10, HMS1921B20, HMS1989L10, HMS2089P13, HMS2092N03, HMS2095H14, HMS2230P15, HMS3259O08, HMS3260B05, HMS3374E02, HMS3402L10, HMS3654B13, HMS3712H14, Pharmakon1600-01502004, KS-00000XN2, ZINC3813061, Tox21_110088, Tox21_500162, ANW-45473, CCG-40125, MFCD00078949, NSC758145, s1287, AKOS015896600, Tox21_110088_1, AC-8115, AN-8345, CS-1821, DB00887, KS-5211, LP00162, MCULE-6802013568, NC00550, NE48825, NSC-758145, Ro-106338, IDI1_000034, IDI1_033978, SMP1_000049, NCGC00015149-01, NCGC00015149-03, NCGC00015149-04, NCGC00015149-05, NCGC00015149-06, NCGC00015149-07, NCGC00015149-08, NCGC00015149-09, NCGC00015149-10, NCGC00015149-11, NCGC00015149-12, NCGC00015149-13, NCGC00015149-15, NCGC00015149-16, NCGC00022072-03, NCGC00022072-04, NCGC00022072-05, NCGC00022072-06, NCGC00022072-07, NCGC00022072-08, NCGC00260847-01, Ro-10-6338, AJ-45693, BC208864, CPD000058418, HY-17468, KB-48483, LS-36330, SAM002564195, SC-12128, SBI-0050150.P003, AB0012138, AB2000031, ST2404803, TC-134218, AB00052253, EU-0100162, FT-0623285, ST51014910, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, D00247, J10080, 28395-03-1,28434-74-4(sodiumsalt), 3-butylamino-4-phenoxy-5-sulphamyl-benzoic acid, AB00052253-15, AB00052253-16, AB00052253_17, AB00052253_18, 3-n-butylamino-4-phenoxy-5-sulfamyl-benzoic acid, 3-n-butylamino-4-phenoxy-5-sulphamyl-benzoic acid, 395B031, A819434, I06-2277, J-017055, SR-01000003062-2, SR-01000003062-4, SR-01000003062-7, BRD-K38197229-001-06-7, BRD-K38197229-001-17-4, Z1550648769, Bumetanide, British Pharmacopoeia (BP) Reference Standard, Bumetanide, European Pharmacopoeia (EP) Reference Standard, Bumetanide, United States Pharmacopeia (USP) Reference Standard

ID: 1342

InChIKey: MAFMQEKGGFWBAB-UHFFFAOYSA-N
SMILES: CCCCNC1=CC=C(C=C1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 7699
synonyms found at PubChem are:
Benzonatate, Benzononatine, Tessalon, Benzononantin, Exangit, 104-31-4, Ventussin, Tessalon-ciba, Ventussin-loz, Benzonatato, Benzonatatum, Tessalin, Tessalon Perles, Tesalon, Benzonatatum [INN-Latin], Benzonatato [INN-Spanish], KM65, Zonatuss, Benzonatate [USAN:INN:BAN], Tessalon perles (TN), 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl p-(butylamino)benzoate, Benzonatate (USP/INN), EINECS 203-194-7, p-(n)-Butylaminobenzoesaeure-(nonaaethylenglykol-monomethylaether)-ester, Polyethyleneglycol-p-n-butylaminobenzoate methyl ester, Benzoic acid, 4-(butylamino)-, 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester, CHEBI:3032, MAFMQEKGGFWBAB-UHFFFAOYSA-N, p-(n)-Butylaminobenzoesaeure-(nonaaethylenglykol-monomethylaether)-ester [German], Benzoic acid, 4-(butylamino)-, 2,5,8,11,14,17,20,23,26-nonaoxaoctacos-28-yl ester, Benzoic acid, p-(butylamino)-, 2-(2-(2-(2-(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl ester, nonaethyleneglycol monomethyl ether p-n-butylaminobenzoate, NCGC00016362-01, CAS-104-31-4, DSSTox_CID_2655, 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 4-(butylamino)benzoate, 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester, DSSTox_RID_76676, DSSTox_GSID_22655, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoate, p-butylaminobenzoic acid omega-O-methylnonaethyleneglycol ester, 3,6,9,12,15,18,21,24,27-nonaoxaoctacosyl 4-butylaminobenzoate, 3,6,9,12,15,18,21,24,27-Nonaoxaoctacos-1-yl 4-(butylamino)benzoate, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-(butylamino)benzoate, 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosyl-4-butylaminobenzoate;3,6,9,12,15,18,21,24,27-Nonaoxaoctacosyl-4-butylaminobenzoate, UNII-5P4DHS6ENR, Benzonatat, Benzonatate [USP:INN:BAN], HSDB 7933, C30H53NO11, benzoate Benzonatato, Tessalon Capsules (TN), AC1L1PCL, Prestwick0_000012, Prestwick1_000012, Prestwick2_000012, Prestwick3_000012, 5P4DHS6ENR, D0Q2ES, AC1Q68HL, SCHEMBL28366, BSPBio_000043, MLS002154171, SPBio_001964, BPBio1_000049, GTPL7611, CHEMBL1374379, DTXSID9022655, CTK8F7974, HMS1568C05, HMS2095C05, HMS2230M19, HMS3373I11, HMS3712C05, KM-65, Pharmakon1600-01503864, ZINC3830276, Tox21_110398, NSC760128, AKOS015891366, Tox21_110398_1, CCG-213706, DB00868, NSC-760128, NCGC00016362-02, NCGC00016362-03, NCGC00016362-05, BC222308, LS-36322, SMR001233469, AB00513795, FT-0622718, D00242, AB00513795_06, SR-01000841197, I01-9684, J-001145, SR-01000841197-2, Nonaethyleneglycol-p-n-butylaminobenzoate methyl ester, 3,6,9,12,15,18,21,24,27-Nonaoxaoctacos-1-yl 4-(butylamino)benzoate #, 4-(butylamino)benzoicacid3,6,9,12,15,18,21,24,27-nonaoxao-ctacos-1-ylester, Benzoic acid,4-(butylamino)-, 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester, benzoicacid,4-(butylamino)-,3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yles, p-(butylamino)-benzoicaci2-(2-(2-(2-(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)e, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl-4-butylaminobenzoate, Benzoic acid, 4-(butylamino)-, 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester (9CI)

ID: 1343

InChIKey: MALFODICFSIXPO-KFKQDBFTSA-N
SMILES: C[C@H]1C[C@H]([C@@H](NC1)[C@@H](C)C2=C(C3=C(C=C2)[C@@H]4CC=C5C[C@H](CC[C@@]5([C@H]4C3)C)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6070
synonyms found at PubChem are:
VERATRAMINE, 60-70-8, NSC 17821, NSC 23880, UNII-RK363YG315, HSDB 3545, BRN 0055515, CHEBI:9951, (3beta,23beta)-14,15,16,17-Tetradehydroveratraman-3,23-diol, RK363YG315, NSC17821, Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3-beta,23-beta)-, (3beta,23R)-14,15,16,17-tetradehydroveratraman-3,23-diol, NSC23880, Veratraman-3, 14,15,16,17-tetradehydro-, (3.beta.,23.beta.)-, WLN: L D6 B566 LU&TTTJ A1 E1 OQ FY1&- BT6MTJ CQ E1, NSC-23880, AC1L1LQI, 5-21-05-00297 (Beilstein Handbook Reference), SCHEMBL335680, CHEMBL464724, MolPort-035-706-563, HY-N0837, ZINC3875407, BDBM50396007, NSC-17821, AKOS030526858, NSC17821;NSC23880, CS-3005, BCP0726000092, LS-162032, X0088, C10829, (3|A,23|A)-14,15,16,17-Teradehydroveratraman-3,23-diol, Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3beta,23beta)-, Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3beta,23beta)- (9CI), (2S,3R,5S)-2-((S)-1-((3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-2,3,4,6,6a,11,11a,11b-octahydro-1H-benzo[a]fluoren-9-yl)ethyl)-5-methylpiperidin-3-ol, (2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methyl-piperidin-3-ol, (2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol, 3-Piperidinol,5-methyl-2-[(1S)-1-[(3S,6aR,11aS,11bR)-2,3,4,6,6a,11,11a,11b-octahydro-3-hydroxy-10,11b-dimethyl-1H-benzo[a]fluoren-9-yl]ethyl]-,(2S,3R,5S)-

ID: 1344

InChIKey: MASYAWHPJCQLSW-ZIAGYGMSSA-N
SMILES: CC[C@@H]1CC2=C(C=CC(=C2)O)C3=C1C4=C(C[C@H]3CC)C=C(C=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 446849
synonyms found at PubChem are:
(R,R)-THC, 138090-06-9, R,R-THC, (R,R)-cis-Diethyl tetrahydro-2,8-chrysenediol, CHEMBL282489, 221368-54-3, (R,R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL, (R,R)-cis-Diethyltetrahydro-2,8-chrysenediol, (5R,11R)-5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol, (5R,11R)-5,11-DIETHYL-5,6,11,12-TETRAHYDRO-2,8-CHRYSENEDIOL, (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, Lopac-D-8690, D04SEX, AC1L9K5Y, Lopac0_000463, MLS002153151, BIDD:ER0043, GTPL2822, DTXSID6040749, SCHEMBL13352540, CTK4E8744, MolPort-003-941-174, HMS2232C18, HMS3261M08, HMS3268D03, ZINC3940885, Tox21_500463, BDBM50436200, AKOS024456895, CCG-204555, LP00463, NCGC00015377-01, NCGC00093877-01, NCGC00093877-02, NCGC00093877-03, NCGC00093877-04, NCGC00093877-05, NCGC00261148-01, SMR001230647, RT-015856, B6909, EU-0100463, D 8690, SR-01000075839, J-007095, SR-01000075839-1, BRD-K66049797-001-02-6, cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol, (5R, 11R)-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol, 2,8-Chrysenediol,5,11-diethyl-5,6,11,12-tetrahydro-, (5R,11R)-, 5,11-cis-diethyl-5,6,11, 12-tetrahydrochrysene-2,8-diol (THC, rac-2b)

ID: 1345

InChIKey: MBABOKRGFJTBAE-UHFFFAOYSA-N
SMILES: COS(=O)(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4156
synonyms found at PubChem are:
METHYL METHANESULFONATE, 66-27-3, Methyl mesylate, Methanesulfonic acid methyl ester, Methanesulfonic acid, methyl ester, methylmethane sulfonate, Methylmethansulfonat, Methyl methanesulphonate, as-Dimethyl sulfite, as-Dimethyl sulphite, Methylmethanesulfonate, Methyl methansulfonate, Methyl methansulphonate, Dimethylsulfonate, MMS, FDA 0092, Methyl ester of methanesulfonic acid, NSC-50256, CB 1540, Methylmethanesulphonate, CCRIS 396, HSDB 5103, Methanesulphonic acid methyl ester, Methyl methanesulfonic acid, Methyl ester of methanesulphonic acid, UNII-AT5C31J09G, C2H6O3S, Methylmethansulfonat [German], as-Dimethyl Sulphate, AI3-50052, Methylester kyseliny methansulfonove, EINECS 200-625-0, BRN 1098586, AT5C31J09G, Methylester kyseliny methansulfonove [Czech], CHEBI:25255, MBABOKRGFJTBAE-UHFFFAOYSA-N, CB1540, methyl methylsulfonate, DSSTox_CID_845, DSSTox_RID_75824, DSSTox_GSID_20845, Methylmesilate, Mesilate, Methyl, CAS-66-27-3, Methyl Methane Sulfonate, Methyl Methylenesulfonate, methylmesylate, dimethylsulfonic acid, methylmethansulphonate, Spectrum_001850, ACMC-209nuh, AC1L1HJG, Spectrum2_000917, Spectrum3_001166, Spectrum4_000776, Spectrum5_001652, Methanesulfonic acid methyl, SCHEMBL63290, BSPBio_002751, KBioGR_001192, KBioSS_002365, SPECTRUM330003, 4-04-00-00011 (Beilstein Handbook Reference), Methyl methanesulfonate, 99%, WLN: WS1&O1, SPBio_000794, CHEMBL313493, Methylsulfonic acid methyl ester, DTXSID7020845, CTK3J2453, KBio2_002362, KBio2_004930, KBio2_007498, KBio3_002251, KS-00000GMU, Methylsulfonic acid, methyl ester, MolPort-003-665-484, (1/4)x>>CEa(1/4)xo yen, NSC50256, ZINC3861020, CDCT-C15100700, Tox21_202094, Tox21_300299, 0180AC, ANW-35175, CCG-39749, SBB058203, AKOS015900695, AN-1925, CS-W004702, LS-1557, MCULE-4411511042, RTR-022444, NCGC00090697-01, NCGC00090697-02, NCGC00090697-03, NCGC00090697-04, NCGC00090697-05, NCGC00090697-06, NCGC00253916-01, NCGC00259643-01, AJ-46110, AS-10021, NCI60_004210, SC-52027, DB-054898, TR-022444, FT-0628902, M0369, ST24031195, ST51015459, C19181, InChI=1/C2H6O3S/c1-5-6(2,3)4/h1-2H, W-104766, I14-16450, Methanesulfonic acid, methyl ester (6CI,7CI,8CI,9CI), Methyl methanesulfonate, certified reference material, TraceCERT(R)

ID: 1346

InChIKey: MBBZMMPHUWSWHV-BDVNFPICSA-N
SMILES: CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 8567
synonyms found at PubChem are:
meglumine, N-Methyl-D-glucamine, 6284-40-8, N-Methylglucamine, Meglumin, 1-Deoxy-1-(methylamino)-D-glucitol, Methylglucamin, Meglumina, 1-Deoxy-1-methylaminosorbitol, D-Glucitol, 1-deoxy-1-(methylamino)-, N-Methyl-D(-)-glucamine, N-Methylsorbitylamine, Megluminum, Megluminum [INN-Latin], UNII-6HG8UB2MUY, Meglumina [INN-Spanish], Sorbitol, 1-deoxy-1-methylamino-, (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol, (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol, NSC 7391, EINECS 228-506-9, N-Methylglucamine solution, NSC 52907, 6HG8UB2MUY, CHEBI:59732, D-(-)-N-Methylglucamine, MBBZMMPHUWSWHV-BDVNFPICSA-N, N-Methylglucamine solution (70% or less), DSSTox_CID_3244, DSSTox_RID_76939, DSSTox_GSID_23244, Glucitol, 1-deoxy-1-(methylamino)-, D-, Meglumine [INN:BAN:JAN], NSC52907, C7H17NO5, Meglumine [USP:INN:BAN:JAN], N-methyl-glucamine, N-Methyl glucamine, NCGC00166125-01, CAS-6284-40-8, EC 228-506-9, AC1L1R9G, AC1Q40UE, AC1Q59OX, SCHEMBL2193, ARONIS27014, BIDD:GT0676, Meglumine (JP17/USP/INN), CHEMBL1200570, DTXSID0023244, MolPort-001-792-068, 1-deoxy-1-(methylamino)-glucitol, 1-Methylamino-1-deoxy-D-glucitol, HMS2089B05, HMS3714B10, Pharmakon1600-01300029, EBD71934, HY-B0342, ZINC2020259, ZX-AT007805, Tox21_112330, Tox21_302037, NSC759607, OR5855, s1974, AKOS005167162, AKOS015850890, N-methyl-1-amino-1-deoxy-D-glucitol, Tox21_112330_1, AC-4692, API0003604, CCG-220884, CS-2384, NSC-759607, KS-0000024U, NCGC00166125-02, NCGC00255365-01, AC-17087, AJ-32761, AK105934, AN-11711, AS-12002, BC211218, KB-58619, SC-18376, SBI-0206683.P002, AB0011121, AB1004789, AX8034404, LS-169031, LS-187348, Meglumine, meets USP testing specifications, ST2419715, TL8004284, AM20100540, FT-0655868, M0227, Meglumine; D-1-Deoxy-1-(methylamino)glucitol, D01796, AB00430469-03, AB00430469_05, C-33964, Glucitol, 1-deoxy-1-(methylamino)-, D- (8CI), SR-05000001446, N-Methyl-D-glucamine, 99.0-100.5% (titration), SR-05000001446-1, BRD-K28595280-001-01-1, N-Methyl-D-glucamine, Vetec(TM) reagent grade, 99%, N-Methyl-D-glucamine, ReagentPlus(R), >=99.0% (T), (2R,3R,4R,5S)-6-methylamino-hexane-1,2,3,4,5-pentaol, (2R,3R,4R,5S)-6-Methylaminohexane-1,2,3,4,5-pentaol, Meglumine, United States Pharmacopeia (USP) Reference Standard, N-methyl-(2 (S),3 (R),4 (R),5 (R),6-pentahydroxy-hexyl)-amine, Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material, N-Methyl-D-glucamine, European Pharmacopoeia (EP) Reference Standard, 131133-75-0, 131337-57-0, 133-52-8, 168828-98-6, 170034-45-4, 184169-59-3, 224432-61-5, 31566-24-2, 45081-44-5, 50560-29-7, 53418-31-8, 61919-50-4, 768396-31-2, 887770-59-4, 901768-29-4, 97780-33-1

ID: 1347

InChIKey: MBGGBVCUIVRRBF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)N2C(=O)C(C(=O)N2C3=CC=CC=C3)CCS(=O)C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5342
synonyms found at PubChem are:
sulfinpyrazone, 57-96-5, Sulphinpyrazone, (+/-)-SULFINPYRAZONE, Sulfinpyrazon, Anturane, Diphenylpyrazone, Sulfoxyphenylpyrazolidine, Anturan, Anturanil, Anturidin, Enturen, Anturano, Sulfinpyrazine, USAF GE-13, 1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)pyrazolidine-3,5-dione, Sulfinpyrazonum, Anturen, Enturan, Apo-Sulfinpyrazone, NSC 75925, Sulfinpirazona, Sulfoxyphenylpyrazolidin, Anturane (TN), G 28315, Sulfinpyrazonum [INN-Latin], Sulfinpirazona [INN-Spanish], Novopyrazone, 4-(Phenylsulfoxyethyl)-1,2-diphenyl-3,5-pyrazolidinedione, 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione, 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine, 4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione, sulfinpyrazone (SPZ), C23H20N2O3S, HSDB 3396, Sulfinpyrazone [USAN:INN:JAN], EINECS 200-357-4, 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-, 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione, BRN 0713597, G 28,315, CHEBI:9342, 1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)-3,5-pyrazolidinedione, 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione, MBGGBVCUIVRRBF-UHFFFAOYSA-N, 1,2-Diphenyl-3,5-dioxo-4-(2'-phenyl-sulfinyl-aethyl)-pyrazolidin, 3,5-Pyrazolidinedione, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-, G-28315, NSC75925, 1,2-Diphenyl-3,5-dioxo-4-(2'-phenyl-sulfinyl-aethyl)-pyrazolidin [German], CAS-57-96-5, NCGC00016255-01, 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl-3,5-pyrazolidinedione, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione, DSSTox_CID_3618, DSSTox_RID_77113, DSSTox_GSID_23618, W-105427, 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl) pyrazolidine, 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenyl-pyrazolidine-3,5-dione, Nu Sulfinpyrazone, Nu-Sulfinpyrazone, Apo Sulfinpyrazone, SMR000058991, SR-01000003152, sufinpyrazone, suphinpyrazone, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-1,2-diazolidine-3,5-dione, Sulphinepyrazolone, Prestwick_455, Sulfinpyrazone [USP:INN:BAN:JAN], (-+)-sulfinpyrazone, Spectrum_001022, Prestwick0_000290, Prestwick1_000290, Prestwick2_000290, Prestwick3_000290, Spectrum2_001324, Spectrum3_000590, Spectrum4_000845, Spectrum5_000984, D03DEI, AC1L1K4Z, BIDD:PXR0096, SCHEMBL34421, BSPBio_000200, BSPBio_002040, KBioGR_001449, KBioSS_001502, MLS000028565, MLS001074941, DivK1c_000090, SPECTRUM1500554, Apotex Brand of Sulfinpyrazone, SPBio_001447, SPBio_002419, BPBio1_000220, GTPL5826, Sulfinpyrazone (JAN/USP/INN), DTXSID0023618, Novartis Brand of Sulfinpyrazone, CTK8F1547, HMS500E12, KBio1_000090, KBio2_001502, KBio2_004070, KBio2_006638, KBio3_001540, Nu Pharm Brand of Sulfinpyrazone, Nu-Pharm Brand of Sulfinpyrazone, MolPort-003-666-286, NINDS_000090, Sulfinpyrazone (JP15/USP/INN), HMS1568J22, HMS1921C09, HMS2092K11, HMS2095J22, HMS2233H11, HMS3259I06, HMS3371B22, HMS3712J22, Pharmakon1600-01500554, BCP05344, KS-00000L9C, Tox21_110331, 8566AB, CCG-39262, NSC-75925, NSC757332, s4628, SBB058184, AKOS015913283, Tox21_110331_1, DB01138, DS-6609, MCULE-8521771467, NC00539, NSC-757332, TRA0061733, IDI1_000090, NCGC00016255-02, NCGC00016255-03, NCGC00016255-04, NCGC00016255-05, NCGC00016255-06, NCGC00016255-07, NCGC00016255-10, NCGC00018267-01, NCGC00023932-03, NCGC00023932-04, AC-13602, AK122319, AN-23594, BC206492, CC-00167, CPD000058991, SAM002554932, (+/-)-Sulfinpyrazone, analytical standard, SBI-0051528.P003, WLN: T5VNNV EHJ BR& CR& E2SO&R, AX8043323, KB-216339, LS-128688, ( inverted exclamation markA)-Sulfinpyrazone, AB00052103, FT-0603240, ST51015125, 4-(Phenylsulfoxyethyl)-1,5-pyrazolidinedione, C07317, D00449, 3, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-, 32301-EP2281815A1, 32301-EP2301933A1, 32301-EP2305640A2, 32301-EP2311827A1, AB00052103_13, C-21796, SR-01000003152-2, SR-01000003152-4, BRD-A36217750-001-05-6, BRD-A36217750-001-09-8, I14-45370, Z1565440323, 1,2-Diphenyl-4-(phenylsulfinylethyl)-3,5-pyrazolidinedione, Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard, 1,2-di(phenyl)-4-(2-phenylsulfinylethyl)pyrazolidine-3,5-dione, 1,2-Diphenyl-3,5-dioxo- 4- (2-phenylsulfinylethyl) pyrazolidine, 1,2-diphenyl-4-[2-(phenylsulfinyl)-ethyl]-pyrazolidine-3,5-dione, Sulfinpyrazone, United States Pharmacopeia (USP) Reference Standard, Sulfinpyrazone for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 1348

InChIKey: MBHNWCYEGXQEIT-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 67356
synonyms found at PubChem are:
Fluphenazine dihydrochloride, Fluphenazine hydrochloride, 146-56-5, Prolixin, Anatensol, Tensofin, Moditen, Permitil, Fluphenazine (dihydrochloride), Lyorodin, Mirenil, OMCA, Trancin, Liogen, FLUPHENAZINE HCL, Calmansial, Flufenazin, Fluphenazine chloride, Permitil hydrochloride, Squibb 4918, UNII-ZOU145W1XL, Dapotum, Fluorophenazine dihydrochloride, CCRIS 4032, EINECS 205-674-1, NSC 179197, ZOU145W1XL, 1-(2-Hydroxyethyl)-4-(3-(2-trifluoromethyl-10-phenothiazinylpropyl)piperazine dihydrochloride, A 4077, Prolixin (TN), 10-(3-(4-(2-Hydroxyethyl)piperazinyl)propyl)-2-trifluoromethylphenothiazine dihydrochloride, 4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazineethanol dihydrochloride, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-, dihydrochloride, 1-piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, dihydrochloride, W-108125, C22H26F3N3OS, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-, dihydrochloride, 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride, SR-01000003048, Fluphenazine DiHCl, 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-ol dihydrochloride, 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol dihydrochloride, 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;dihydrochloride, Prestwick_225, Fluphenazine hydrochloride [BAN:JAN], Fluphenazine hydrochloride [USP:BAN:JAN], AC1Q3ALH, AC1L27DO, C22H27ClF3N3OS, SCHEMBL41634, SPECTRUM1500994, CHEBI:5126, FLUFENAZINE HYDROCHLORIDE, CHEMBL1448187, CTK8F9824, MBHNWCYEGXQEIT-UHFFFAOYSA-N, MolPort-000-917-736, HMS1568P22, HMS1921O14, BCP18079, HY-A0081, Tox21_500555, GP2994, MFCD00055212, s4569, Fluphenazine hydrochloride (JAN/USP), AKOS015960787, API0002739, CCG-212902, CS-4290, LP00555, NCGC00093941-01, NCGC00093941-02, NCGC00093941-03, NCGC00261240-01, AC-12201, S4569 Fluphenazine (dihydrochloride).cd, AB0019790, LS-112567, EU-0100555, FT-0668755, V0295, D00791, F 4765, SR-01000003048-2, SR-01000003048-9, Z2784093501, Fluphenazine Dihydrochloride 1.0 mg/ml in Methanol (as free base), Fluphenazine dihydrochloride, European Pharmacopoeia (EP) Reference Standard, 4-[3-[2-(Trifluoromethyl)-10H-pheno-thiazin-10-yl]-1-piperazineethanol 2HCl, 4-[3-[2-(Trifluoromethyl)-10H-pheno-thiazin-10-yl]-1-piperazineethanol dihydrochloride, Fluphenazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Fluphenazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 2-(4-{3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-1-piperazinyl)ethanol dihydrochloride, 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol,dihydrochloride, 36315-90-9, Fluphenazine dihydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, AKOS024366260, MCULE-5539512526, ST50999687, 2-(4-{3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl}piperazinyl)ethan-1-ol, chloride, chloride, AKOS026749778

ID: 1349

InChIKey: MBMQEIFVQACCCH-QBODLPLBSA-N
SMILES: C[C@H]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281576
synonyms found at PubChem are:
ZEARALENONE, 17924-92-4, trans-Zearalenone, (-)-Zearalenone, F-2 toxin, Mycotoxin F2, (S)-(-)-Zearalenone, Zenone, (S)-Zearalenone, Toxin F2, (10S)-Zearalenone, CCRIS 623, UNII-5W827M159J, CHEBI:10106, HSDB 4208, NCI-C50226, Compound F-2, EINECS 241-864-0, 6-(10-Hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylic acid lactone, BRN 1350216, MLS000097901, CHEMBL454173, (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, MBMQEIFVQACCCH-QBODLPLBSA-N, C18H22O5, 5W827M159J, (S-(E))-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (3S,11E)-, SMR000058177, DSSTox_CID_1460, Benzoxacyclotetradec-11-en-1-one, 14,16-dihydroxy-3-methyl-7-oxo-, trans-, Resorcylic acid, 6-(10-hydroxy-6-oxo-1-undecenyl)-, mu-lactone, trans-, DSSTox_RID_76167, DSSTox_GSID_21460, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S)-(-)-, (2E,11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,14,16-tetraene-7,13-dione, (S,E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione, [S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, F2 Toxin, CAS-17924-92-4, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(E))-, ntoxin f2, (S)-Zear alenone, Compound F-2, AC1NQYNP, Opera_ID_1608, Epitope ID:146094, SCHEMBL33754, SCHEMBL33755, BSPBio_003581, Zearalenone, fungal mycotoxin, MLS000028817, MLS000888273, MLS001174881, BIDD:ER0058, SPECTRUM1505290, Zearalenone, reference material, fermentation estrogenic substance, 6-(10-Hydroxy-6-oxo-trans-1-undecenyl)-.beta.-resorcylic acid lactone, DTXSID0021460, REGID_for_CID_657988, MolPort-001-017-582, MolPort-044-723-584, REGID_for_CID_5281576, (E)-3,4,5,6,7,8,9,10-Octahydro-14,16-dihydroxy-3-methyl-7-oxo-1H-2-benzoxacyclotetradecin-1-one, 1H-2-Benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10-octahydro-14,16-dihydroxy-3-methyl-7-oxo-, (E)-, ALBB-030793, BCP06062, ZINC3881412, Tox21_201153, Tox21_303510, BBL010576, BDBM50247676, CCG-40041, LMPK04000016, LS-946, MFCD00133085, STK033813, AKOS001577898, benzoxacyclotetradecin-1,7(8H)-dione, QC-9992, SDCCGMLS-0066858.P001, NCGC00038520-03, NCGC00090809-01, NCGC00090809-02, NCGC00257246-01, NCGC00258705-01, (3S,11E)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, (S-(Z))-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(Z))-, 36455-70-6, B7556, C09981, 924Z924, J-011439, BRD-K42017082-001-02-6, trans-6-(10-hydroxy-6-oxo-1-undecenyl)resorcylic acid mu-lactone, 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylic acid N-lactone, trans-14,16-dihydroxy-3-methyl-7-oxobenzoxacyclotetradec-11-en-1-one, Zearalenone solution, 100 mug/mL in acetonitrile, analytical standard, (-)-(3S,11E)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1, 7(8H)-dione, (-)-(3S,11E)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, (2E,11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14), 2,15,17-tetraene-7,13-dione, (S)-(- )-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, (S)-(-)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione, 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (3S)-, 2beta-Methyl-15,17-dihydroxy-12,13-butano-1-oxacyclotetradecane-10,15(13),16,18(12)-tetraene-6,14-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)dione, Zearalenone solution, certified reference material, 50 mug/mL in acetonitrile, ampule of 1 mL

ID: 1350

InChIKey: MBNGWHIJMBWFHU-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281612
synonyms found at PubChem are:
Diosmetin, 520-34-3, Luteolin 4'-methyl ether, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one, 4'-Methylluteolin, Salinigricoflavonol, 5,7,3'-Trihydroxy-4'-methoxyflavone, Diosmetine, UNII-TWZ37241OT, Luteolin 4-methyl ether, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, 3',5,7-trihydroxy-4'-methoxyflavone, CHEBI:4630, TWZ37241OT, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, MFCD00017425, 5,7-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chromen-4-one, Pillon, SR-05000002196, 2-(4-methoxy-3-oxidanyl-phenyl)-5,7-bis(oxidanyl)chromen-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one, HSDB 8101, EINECS 208-291-8, AC1NQYQA, Spectrum_001505, SpecPlus_000435, Spectrum2_001638, Spectrum3_000987, Spectrum4_001113, Spectrum5_001707, D00RFY, BSPBio_002653, KBioGR_001586, KBioSS_001985, MLS006011843, CHEMBL90568, Diosmetin, analytical standard, DivK1c_006531, SCHEMBL289337, SPBio_001735, BIDF1026, BDBM23414, KBio1_001475, KBio2_001985, KBio2_004553, KBio2_007121, KBio3_001873, DTXSID80199966, MBNGWHIJMBWFHU-UHFFFAOYSA-N, MolPort-003-665-821, ZX-AFC000182, HMS3656G13, BCP28283, HY-N0125, KS-00000G2R, ZINC5733652, BBL027839, CCG-38758, CD-995, CD0173, Diosmetin (Luteolin 4-methyl ether), LMPK12110824, s2380, SBB066130, STL146390, AKOS005720974, CS-5455, DB11259, MCULE-4793583546, SDCCGMLS-0066783.P001, VA10746, 3',5,7-trihydroxy-4'-methoxy flavone, NCGC00163540-01, NCGC00163540-02, NCGC00163540-03, NCGC00178549-01, AJ-54668, AK111246, AN-45521, CC-27081, SC-13558, SMR002044787, AX8125774, KB-244290, LS-193890, FT-0603442, ST24044110, ST50331610, X1126, C10038, 520D343, A828900, A828902, C-18748, I06-0517, SR-05000002196-2, SR-05000002196-3, BRD-K26862302-001-02-9, BRD-K26862302-001-03-7, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one (Diosmetin)

ID: 1351

InChIKey: MBRHNTMUYWQHMR-UHFFFAOYSA-N
SMILES: CC1=CC(=O)N(C(=C1)C2CCCCC2)O.C(CO)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 38911
synonyms found at PubChem are:
Ciclopirox olamine, 41621-49-2, Ciclopirox ethanolamine, ciclopiroxolamine, Ciclopiroxolamin, Ciclobirox Olamine, Micoxolamina, Brumixol, Ciclopirox (olamine), HOE 296, UNII-50MD4SB4AP, Ciclopirox ethanolamine salt (1:1), EINECS 255-464-9, NSC 336278, 50MD4SB4AP, MLS003170863, NSC336278, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone compound with 2-aminoethanol (1:1), NCGC00017112-01, HOE-296, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt, CAS-41621-49-2, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone, 2-aminoethanol salt, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridon, 2-aminoethanol-salz [German], 2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-, compd. with 2-aminoethanol (1:1), 2-Aminoethanol compd. with 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone (1:1), 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone compd. with 2-aminoethanol (1:1), 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethanol (1:1), 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1), DSSTox_CID_25583, DSSTox_RID_80979, DSSTox_GSID_45583, 6-Cyclohexyl-1-hydroxy-4-methyl-2[1H]-pyridone ethanolamine salt, MLS002153867, 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one 2-aminoethanol (1:1), 2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-, compound with 2-aminoethanol (1:1), SR-05000001589, SMR001233223, Kopcycloamine, Ciclochem, Ciclopirox olamine [USAN:JAN], C12H17NO2.C2H7NO, RV4104A, Prestwick_785, ethanolamine; penlac, 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one, Ciclopirox olamine [USAN:USP:JAN], Spectrum_000150, ciclopirox; ethanolamine, Ciclopirox Olamine,(S), Ciclopirox Olamine USP/EP, AC1L20NJ, SCHEMBL66960, KBioSS_000630, KSC585A4B, DivK1c_000705, SPECTRUM1500189, Ciclopirox olamine (JAN/USP), CHEMBL242580, DTXSID6045583, CTK4I5040, HMS502D07, HY-B0450A, KBio1_000705, KBio2_000630, KBio2_003198, KBio2_005766, MolPort-003-666-145, NINDS_000705, HMS1569N03, HMS1920O09, HMS2091E16, HMS2096N03, HMS2232B06, HMS3656B16, HMS3713N03, Pharmakon1600-01500189, Tox21_110781, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridon, 2-aminoethanol-salz, CCG-38945, NSC756694, s3019, AKOS015891685, Tox21_110781_1, API0001593, Ciclopirox olamine, analytical standard, CS-4767, KS-5086, NSC-336278, NSC-756694, IDI1_000705, KS-00000L46, NCGC00017112-02, NCGC00017112-03, NCGC00017112-10, NCGC00094623-01, NCGC00094623-02, AC-14469, AK117743, AT-26026, CC-25777, NCI60_002954, SC-18619, AB0011793, LS-133030, RT-000334, RT-000352, FT-0082621, FT-0602960, ST24045332, ST51039041, 42C050, D01364, J10104, K-8752, A825610, I02-0672, SR-05000001589-1, SR-05000001589-3, 2(1H)-Pyridinone, compd. with 2-aminoethanol (1:1), 2-aminoethanol; 6-cyclohexyl-1-hydroxy-4-methyl-2-pyridinone, 2-aminoethanol; 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one, 2-aminoethanol; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one, 2-azanylethanol; 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Ciclopirox olamine, European Pharmacopoeia (EP) Reference Standard, 6-cyclohexyl-1-hydroxy-4-methylhydropyridin-2-one, 2-aminoethan-1-ol, Ciclopirox olamine, United States Pharmacopeia (USP) Reference Standard, 2-Aminoethanol compd. with 6-cyclohexyl-1-hydroxy-4-methyl- 2(1H)-pyridinone (1:1), 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethanol (1, 6->>.(1/4) masculine>>u-1-oC>>u-4-(1/4)x>>u-2(1H)-ssAa currencyI feminine OO (1/4) degrees .NI

ID: 1352

InChIKey: MBZKDBQDALOSRP-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(O1)C=C3C(=C2OC)C(=C(C(=O)O3)C4=CC=C(C=C4)OC)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 54677407
synonyms found at PubChem are:
Robustic acid, 5307-59-5, 2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one, 4-hydroxy-5-methoxy-3-(4-methoxyphenyl)-8,8-dimethyl-, 2H,8H-Benzo(1,2-b:5,4-b')dipyran-2-one, 4-hydroxy-5-methoxy-3-(4-methoxyphenyl)-8,8-dimethyl-, Spectrum_000556, SpecPlus_000613, AC1Q6HZA, Spectrum2_001165, Spectrum3_001802, Spectrum4_001592, Spectrum5_000304, AC1L52XL, BSPBio_003383, KBioGR_002204, KBioSS_001036, SPECTRUM240673, DivK1c_006709, SCHEMBL572212, SPBio_001149, CHEMBL400777, SCHEMBL15941305, CHEBI:92953, CTK4J7026, KBio1_001653, KBio2_001036, KBio2_003604, KBio2_006172, KBio3_002886, DTXSID30201149, MBZKDBQDALOSRP-UHFFFAOYSA-N, CCG-39045, LMPK12160025, 8-hydroxy-5-methoxy-7-(4-methoxyphenyl)-2,2-dimethyl-2h,6h-pyrano[3,2-g]chromen-6-one, NCGC00095552-01, NCGC00095552-02, 2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one, 4-hydroxy-5-methoxy-3-(p-methoxyphenyl)-8,8-dimethyl-, SR-05000002632, SR-05000002632-1, BRD-K54411430-001-02-5, 4-Hydroxy-5-methoxy-3-(4-methoxyphenyl)-8,8-dimethyl-2H,8H-pyrano[3,2-g]chromen-2-one #, 8-hydroxy-5-methoxy-7-(4-methoxyphenyl)-2,2-dimethylpyrano[3,2-g]chromen-6-one, 2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one,4-hydroxy-5-methoxy-3-(4-methoxyphenyl)-8,8-dimethyl-

ID: 1353

InChIKey: MBZYKEVPFYHDOH-BQNIITSRSA-N
SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 440560
synonyms found at PubChem are:
24,25-Dihydrolanosterol, Lanostenol, Dihydrolanosterol, 79-62-9, Dihydrolanosterin, 5alpha-Lanost-8-en-3beta-ol, UNII-9H273A8B2X, 24-dihydrolanosterol, 9H273A8B2X, (3S,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, 3beta-Hydroxylanost-8-ene, 5alpha-Lanost-8-en-3 beta-ol, Lanost-8-en-3-ol, (3.beta.)-, Lanosterol, dihydro-, Lanost-8-en-3-ol, Lanost-8-en-3beta-ol, Lanost-8-en-3-ol #, Lanost-8-en-3.beta.-ol, AC1L99IO, SCHEMBL288306, (3beta)-Lanost-8-en-3-ol, CHEBI:28113, MBZYKEVPFYHDOH-BQNIITSRSA-N, LMST01010087, 4,4,14a-trimethyl-5a-cholesta-8-en-3b-ol, C05109, 4,4,14alpha-trimethyl-5alpha-cholesta-8-en-3beta-ol, UNII-U431865SO1 component MBZYKEVPFYHDOH-BQNIITSRSA-N, (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, 483329-03-9

ID: 1354

InChIKey: MCTWTZJPVLRJOU-UHFFFAOYSA-N
SMILES: CN1C=CN=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1390
synonyms found at PubChem are:
1-methylimidazole, 1-Methyl-1H-imidazole, N-Methylimidazole, 616-47-7, 1H-Imidazole, 1-methyl-, IMIDAZOLE, 1-METHYL-, n-methyl imidazole, 1-methyl-imidazole, UNII-P4617QS63Y, N-methylimidazol, 1-methylimdazole, 1-methylimidazol, EINECS 210-484-7, 1-methyl-1h-imidazol, NSC 88064, CHEBI:113454, MCTWTZJPVLRJOU-UHFFFAOYSA-N, P4617QS63Y, 120418-32-8, cap b, lupragen(r) nmi, 3-methylimidazole, N-methyl-imidazol, N-methyl-imidazole, 1-methyl imidazole, 1-N-methylImidazole, PubChem15971, 1H-Imidazole, methyl-, AC1L1BDE, AC1Q3ZYQ, Lopac-M-8878, 1-methyl-(1H)-imidazole, ACMC-209mv3, CHEMBL543, 1-Methyl-1H-imidazole #, EC 210-484-7, DSSTox_CID_30863, WLN: T5N CNJ A1, DSSTox_GSID_52291, Lopac0_000831, KSC220I5J, BDBM7884, DTXSID6052291, CTK1C0454, MolPort-000-157-227, HMS3262H03, 1-Methylimidazole, 99% 100g, NSC88064, STR00990, ZINC6165925, Methimazole (Thiamazole) Impurity B, Tox21_304006, Tox21_500831, ANW-33901, BBL011447, CM0166, MFCD00005292, NSC-88064, SBB007574, STL146559, AKOS000119840, ZINC328578773, CCG-204915, CS-W008580, LP00831, LS20202, MCULE-1857627459, MP-2113, PS-9372, RL04331, RP18398, RTR-021226, TRA0049512, NCGC00015702-01, NCGC00015702-02, NCGC00015702-03, NCGC00015702-04, NCGC00094162-01, NCGC00094162-02, NCGC00261516-01, NCGC00357222-01, 1-Methylimidazole, ReagentPlus(R), 99%, AN-21962, BC680917, CAS-616-47-7, KB-12921, LS-78779, SC-25626, DB-002020, ST2408809, TL8003918, TR-021226, EU-0100831, FT-0632577, M0508, ST45136381, 1-Methylimidazole, puriss., >=99.0% (GC), M 8878, 12411-EP2280000A1, 12411-EP2281820A2, 12411-EP2298754A1, 12411-EP2301934A1, 12411-EP2305695A2, 12411-EP2305696A2, 12411-EP2305697A2, 12411-EP2305698A2, 12411-EP2311494A1, 12411-EP2316974A1, 81941-EP2281820A2, 81941-EP2286915A2, 81941-EP2295438A1, 81941-EP2295503A1, 81941-EP2298754A1, 81941-EP2305676A1, 1-Methylimidazole, Vetec(TM) reagent grade, 98%, 113549-EP2281820A2, 113549-EP2298754A1, SR-01000076013, I11-0488, Q-200126, SR-01000076013-1, 1-Methylimidazole, >=99%, purified by redistillation, F0001-1635, Z821681528, InChI=1/C4H6N2/c1-6-3-2-5-4-6/h2-4H,1H, 110069-11-9, 1167574-49-3, 1174917-56-6, 1179540-68-1, 1235442-19-9, 1246941-20-7, 1259523-87-9, 1357171-90-4, 1359978-71-4, 142504-34-5, 30346-87-3, 674282-80-5, 69723-05-3, 864745-22-2, 955156-62-4, Cap B (1-methylimidazole 16% in THF), for oligonucleotide synthesis, filtered through a 1mum filter

ID: 1355

InChIKey: MCWFXQXXVFZOIE-UHFFFAOYSA-N
SMILES: COC1=C(C2=C(C=C1)C=C(C=C(C2=O)OC)C(=O)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4020695
synonyms found at PubChem are:
METHYL 7-DESOXYPURPUROGALLIN-7-CARBOXYLATE TRIMETHYL ETHER, KBio2_000832, Spectrum_000352, SpecPlus_000080, Spectrum2_000455, Spectrum3_000251, Spectrum4_001549, Spectrum5_000118, AC1N2ES9, BSPBio_001662, KBioGR_002018, KBioSS_000832, SPECTRUM210522, DivK1c_006176, SPBio_000530, CHEMBL1564552, CHEBI:93119, KBio1_001120, KBio2_003400, KBio2_005968, KBio3_001162, CCG-38697, NCGC00095521-01, NCGC00095521-02, NCGC00179106-01, BRD-K63938928-001-01-7, methyl 3,4,6-trimethoxy-5-oxobenzo[7]annulene-8-carboxylate

ID: 1356

InChIKey: MCWXGJITAZMZEV-UHFFFAOYSA-N
SMILES: CNC(=O)CSP(=S)(OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3082
synonyms found at PubChem are:
dimethoate, Phosphamide, 60-51-5, Rogor, Aadimethoal, Fosfamid, Fosfotox, Perfecthion, Perfekthion, Phosphamid, Rebelate, Sinoratox, Sistemin, Systoate, Daphene, Dimeton, Dimevur, Racusan, Roxion, Cygon, Lurgo, Tara, Fosfatox R, Fosfotox R, Cygon insecticide, De-fend, Fostion MM, Rogor L, Rogor P, Cygon 4E, Fosfotox R 35, Cekuthoate, Devigon, Dimetate, Dimethogen, Ferkethion, Rogodan, Sevigor, Trimetion, Cygon 2-E, Rogor 40, Salut, Solut, Cygon 400, Fortion NM, Roxion UA, Tara 909, Fosfamid (USSR), American cyanamid 12880, Dimethoaat [Dutch], Dimethoat [German], Dimethoate 30 EC, 8014 Bis HC, Demos-L40, Rogor 20L, Dimate 267, Caswell No. 358, Dimethoat Tech 95%, PEI 75, BI 58, BI-58, RCRA waste number P044, CCRIS 245, 2-Dimethoxyphosphinothioylthio-N-methylacetamide, C5H12NO3PS2, Dimethoate [ANSI:BSI:ISO], UNII-W6U08B045O, BI 58 EC, OMS 94, CL 12880, HSDB 1586, Experimental Insecticide 12,880, NCI-C00135, EINECS 200-480-3, RCRA waste no. P044, ENT 24,650, EPA Pesticide Chemical Code 035001, BRN 1785339, AC-12880, AC-18682, EI-12880, Phosphorodithioic acid, O,O-dimethyl S-(2-(methylamino)-2-oxoethyl) ester, O,O-Dimethyl S-methylcarbamoylmethyl phosphorodithioate, S-Methylcarbamoylmethyl O,O-Dimethyl phosphorodithioate, O,O-Dimethyl S-(N-methylcarbamoylmethyl) dithiophosphate, AI3-24650, Phosphorodithioic acid, O,O-dimethyl ester, S-ester with 2-mercapto-N-methylacetamide, O,O-Dimethyl S-(N-methylcarbamoylmethyl) phosphorodithioate, L-395, CHEBI:34714, o,o-Dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate, MCWXGJITAZMZEV-UHFFFAOYSA-N, W6U08B045O, Phosphorodithioic acid, O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] ester, 2-dimethoxyphosphinothioylsulfanyl-N-methylacetamide, O,O-Dimethyl methylcarbamoylmethyl phosphorodithioate, FIP, O,O-Dimethyl S-((methylcarbamoyl)methyl)phosphorodithioate, N-Monomethylamide of O,O-dimethyldithiophosphorylacetic acid, O,O-Dimethyl S-(N-methylcarbamylmethyl) thiothionophosphate, O,O-Dimethyl-S-(2-oxo-3-aza-butyl)-dithiophosphat [German], O,O-Dimethyl S-(2-(methylamino)-2-oxoethyl) phosphorodithioate, O,O-Dimethyl-dithiophosphorylessigsaeure monomethylamid [German], O,O-Dimethyl-S-(N-monomethyl)-carbamyl methyl dithiophosphate, O,O-Dimethyldithiophosphorylacetic acid, N-monomethylamide salt, O,O-Dimetil-S-(N-metil-carbamoil-metil)-ditiofosfato [Italian], Acetic acid, O,O-dimethyldithiophosphoryl-, N-monomethylamide salt, DSSTox_CID_479, O,O-Dimethyl-S-(N-methyl-carbamoyl)-methyl-dithiofosfaat [Dutch], Dithiophosphate de O,O-dimethyle et de S(-N-methylcarbamoyl-methyle) [French], DSSTox_RID_75615, Phosphorodithioic acid O,O-dimethyl ester, ester with 2-mercapto-N-methylacetamide, DSSTox_GSID_20479, Dimethoaat, Dimethoat, O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] phosphorodithioate, CAS-60-51-5, Turbair, Defend, Dimethoate solution, Fostion M M, Rogor 20 L, Spectrum_001793, SpecPlus_000384, Spectrum2_001861, Spectrum3_000812, Spectrum4_000652, Spectrum5_001934, AC1L1F4T, SCHEMBL18159, BSPBio_002303, KBioGR_001023, KBioSS_002286, SPECTRUM330020, MLS002207196, BIDD:ER0567, Dimercaptan Triethylene Glycol, DivK1c_006480, O,O-Dimethyl-S-(2-oxo-3-aza-butyl)-dithiophosphat, SPBio_001702, Dimethoate, analytical standard, O,O-Dimethyl-dithiophosphorylessigsaeure monomethylamid, O,O-Dimetil-S-(N-metil-carbamoil-metil)-ditiofosfato, CHEMBL1569524, DTXSID7020479, Experimental Insecticide 12880, KBio1_001424, KBio2_002284, KBio2_004852, KBio2_007420, KBio3_001803, MCWXGJITAZMZEV-UHFFFAOYSA-, O,O-Dimethyl-S-(N-methyl-carbamoyl)-methyl-dithiofosfaat, O,O-Dimethyl-S-(N-methyl-carbamoyl-methyl)-dithiophosphat, MolPort-003-665-438, Tox21_202246, Tox21_301161, CCG-39399, Dithiophosphate de O,O-dimethyle et de S(-N-methylcarbamoyl-methyle), ENT-24650, KM0411, LS-262, O,O-Dimethyl-S-(N-methyl-carbamoyl-methyl)-dithiophosphat [German], Dimethoate 100 microg/mL in Acetone, AKOS015960721, Dimethoate 10 microg/mL in Cyclohexane, O,O-Dimethyl phosphorodithioate S-ester with 2-mercapto-N-methylacetamide (8CI), Dimethoate 10 microg/mL in Acetonitrile, NCGC00094518-01, NCGC00094518-02, NCGC00094518-03, NCGC00094518-04, NCGC00094518-05, NCGC00094518-06, NCGC00094518-07, NCGC00094518-08, NCGC00255059-01, NCGC00259795-01, 56833-73-9, AN-41814, AS-16078, CC-26881, CJ-32573, Dimethoate 100 microg/mL in Acetonitrile, S245, SMR000777935, FT-0603252, Dimethoate, PESTANAL(R), analytical standard, C14326, 26852-EP2274983A1, 26852-EP2275422A1, 26852-EP2280009A1, 26852-EP2305662A1, 26852-EP2308857A1, 26852-EP2308858A1, 26852-EP2311816A1, 26852-EP2311817A1, 26852-EP2314583A1, 26852-EP2374786A1, 42068-EP2311808A1, 42068-EP2311829A1, 053D676, C-13239, 2-dimethoxyphosphinothioylsulfanyl-N-methyl-acetamide, BRD-K94763113-001-02-5, Dimethyl S-((methylcarbamoyl)methyl) phosphorodithioate, Dimethyl S-(N-(methylcarbamoyl)methyl) phosphorodithioate, Dimethyl S-(N-(methylcarbamoyl)methyl) phosphorodithioate, Dimethoate Solution, 10 mg/L, 10 mL (RM, ISO GUIDE 34), Dimethoate Solution, 100 mg/L, 1 ml (RM, ISO GUIDE 34), O,O-Dimethyl S-(N-Methyl carbamoylmethyl) Phosphorodithioate, O,O-Dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate #, O,O-dimethyl S-2-(methylamino)-2-oxoethyl phosphorodithioate, O,O-Dimethyl-S-(N-methyl-carbamoyl-methyl)-dithiophosphat [German], Dimethyl phosphorodithioate, S-ester with 2-mercapto-N-methylacetamide, O,O-Dimethyl phosphorodithioate S-ester with 2-mercapto-N-methylacetamide, Phosphorodithio ic Acid O,O-Dimethyl S-(2-(Methylamino)-2-Oxoethyl) Ester, Phosphorodithioic Acid O,O-Dimethyl S-(2-(Methylamino)-2-Oxoethyl) Ester, Phosphorodithioic acid, O,O-Dimethyl S-(2-(methylamino)-2-oxoethylyl)ester, InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7), 11003-53-5, 11096-20-1, 79956-18-6, Benzoic acid, 4-[4-[[5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-

ID: 1357

InChIKey: MDIGAZPGKJFIAH-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1O)C(=CN2)CCN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 160436
synonyms found at PubChem are:
Serotonin hydrochloride, 153-98-0, 5-Hydroxytryptamine hydrochloride, 3-(2-aminoethyl)-1H-indol-5-ol hydrochloride, Serotonin HCl, 5-Hydroxytryptamine HCl, UNII-GKN429M9VS, CCRIS 4420, 1H-Indol-5-ol, 3-(2-aminoethyl)-, monohydrochloride, GKN429M9VS, CHEMBL535832, 3-(2-aminoethyl)indol-5-ol, chloride, H-8140, 3-(2-Aminoethyl)-5-hydroxyindole hydrochloride, SMR000875214, Prestwick_447, SR-01000075577, Serotonin, HCl, 5-HT hydrochloride, AC1L4NLY, AC1Q3F6Y, MLS001332607, MLS001332608, MLS002153834, SCHEMBL379650, Serotonin hydrochloride, powder, 3-(2-aminoethyl)-1h-indol-5-ol hydrochloride(1:1), 3-(2-AMINO-ETHYL)-1H-INDOL-5-OL HYDROCHLORIDE, 5-Hydroxytryptamine hydrochioride, CTK3J3022, DTXSID80165186, 5-hydroxy tryptamine hydrochloride, MDIGAZPGKJFIAH-UHFFFAOYSA-N, MolPort-003-933-638, HMS1569B03, 3-(2-Aminoethyl)indol-5-ol HCl, BCP20357, HY-B1473, KS-00000FV4, EINECS 244-464-4, Tox21_500607, ANW-43151, CH-185, MFCD00012686, s4244, SBB003418, 5-Hydroxytryptamine Hydrochloride,(S), AKOS016010442, AN-6665, CCG-214216, GS-3130, LP00607, MCULE-8194058321, QC-1340, RTR-006392, NCGC00093982-01, NCGC00093982-02, NCGC00261292-01, AK116036, CC-21880, I380, LS-83659, SC-80561, ST056223, 3-(2-Aminoethyl)indol-5-ol hydrochloride, AB0013658, AX8011987, DB-043206, TR-006392, 4CH-024660, CS-0013171, EU-0100607, FT-0631852, S0370, ST24041389, H 9523, X-1770, 3-(2-aminoethyl)-1H-indol-5-ol, hydrochloride, 3-(2-azanylethyl)-1H-indol-5-ol hydrochloride, 153S980, A809482, C-11185, SR-01000075577-1, SR-01000075577-5, I14-111700, 21591-86-6, SCHEMBL17360646, Serotonin hydrochloride, 99% 1g, AKOS026750383

ID: 1358

InChIKey: MDKCFLQDBWCQCV-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CN=C=S

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2346
synonyms found at PubChem are:
benzyl isothiocyanate, 622-78-6, (Isothiocyanatomethyl)benzene, Benzylisothiocyanate, Benzyl mustard oil, Benzylsenfoel, Tromacaps, Tromalyt, Urogran, Isothiocyanic acid, benzyl ester, Benzyl-isothiocyanate, Benzene, (isothiocyanatomethyl)-, isothiocyanatomethylbenzene, Isothiocyanic Acid Benzyl Ester, Benzylsenfoel [German], AB 2 (VAN), alpha-isothiocyanatotoluene, Isothiocyanotaomethylbenzene, isothiocyanatomethyl-benzene, UNII-871J6YOR8Q, NSC 118976, Toluene, alpha-isothiocyanato-, BITC, CCRIS 3145, EINECS 210-753-9, BRN 0386135, (isothiocyanatomethyl)-benzene, CHEMBL55285, AI3-02736, 871J6YOR8Q, AB 2, CHEBI:17484, Toluene, .alpha.-isothiocyanato-, MDKCFLQDBWCQCV-UHFFFAOYSA-N, NSC118976, Benzylsenfoel (german), phenylmethanisothiocyanate, PMITC cpd, a-isothiocyanatotoluene, SR-05000002381, phenylmethyl isothiocyanate, Tromocaps, Benzyl isothio cyanate, PubChem14549, Spectrum_001820, SpecPlus_000684, Tromalyt active substance, AC1Q7EYE, DSSTox_CID_155, Spectrum2_000852, Spectrum3_000793, Spectrum4_001059, Spectrum5_001837, WLN: SCN1R, ACMC-209n1k, Isothiocyanatomethyl)benzene, NCIMech_000859, AC1L1DH3, AC1Q7EX9, alpha-Isothiocyanato-Toluene, isothiocyanato-methyl-benzene, Benzyl isothiocyanate, 98%, DSSTox_RID_75407, DSSTox_GSID_20155, SCHEMBL44145, BSPBio_002526, KBioGR_001358, KBioSS_002323, 4-12-00-02276 (Beilstein Handbook Reference), KSC250O3D, Benzene, isothiocyanatomethyl-, DivK1c_006780, SPECTRUM1503006, SPBio_000863, (Isothiocyanatomethyl)benzene #, 1-(isothiocyanatomethyl)benzene, BITC, 17, Toluene, alpha -isothiocyanato-, DTXSID0020155, CTK1F0731, FEMA 4428, KBio1_001724, KBio2_002321, KBio2_004889, KBio2_007457, KBio3_001746, KS-00001PQO, TIMTEC-BB SBB002731, AKOS JY2090023, Benzyl isothiocyanate, 98%, FG, MolPort-000-147-097, OTAVA-BB 1055640, HMS1921P18, Pharmakon1600-01503006, (Isothiocyanatomethyl)benzene, 9CI, KS-00000V2U, ZERO/008132, ZINC1529592, AKOS BBS-00004442, Tox21_201191, ANW-34134, BBL013129, BDBM50240520, CCG-35868, MFCD00004819, NSC758206, SBB002731, STK399787, AKOS000212138, AS04379, LS-7216, LS11773, MCULE-5989558191, NSC-118976, NSC-758206, RTR-033289, SDCCGMLS-0066697.P001, QTL1_000013, NCGC00094982-01, NCGC00094982-02, NCGC00094982-03, NCGC00094982-04, NCGC00258743-01, Benzyl isothiocyanate, analytical standard, BP-12924, CAS-622-78-6, CJ-23924, KB-75435, NCI60_000455, PS-10308, SC-13625, SBI-0052749.P002, DB-022613, TL8004089, TR-033289, FT-0622167, I0224, ST50214559, C03098, AB00053249_03, I09-2433, J-650076, SR-05000002381-1, SR-05000002381-2, F0001-1663, 58019-05-9

ID: 1359

InChIKey: MDKGKXOCJGEUJW-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5359
synonyms found at PubChem are:
suprofen, 40828-46-4, Profenal, Sutoprofen, Suprol, Maldocil, Masterfen, p-2-Thenoylhydratropic acid, Suprofene, Suprofenum, Suprocil, Suprofene [INN-French], Suprofenum [INN-Latin], 4-(2-Thenoyl)hydratropsaeure, Srendam, Sulproltin, Topalgic, 2-(4-(2-Thenoyl)phenyl)propionsaeure, TN 762, (+-)-2-(p-(2-Thenoyl)phenyl)propionic acid, Suprofen (Profenal), R 25061, 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid, alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid, Profenol, C14H12O3S, R-25061, R-25,061, Profenal (TN), NSC 303611, CHEBI:9362, Suprofen [USAN:BAN:INN:JAN], Hydratropic acid, p-(2-thenoyl)-, EINECS 255-096-9, TN-762, CHEMBL956, Suprofen (JAN/USP/INN), TYN-762P, Benzeneacetic acid, .alpha.-methyl-4-(2-thienylcarbonyl)-, MDKGKXOCJGEUJW-UHFFFAOYSA-N, 2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid, NSC303611, Benzeneacetic acid, alpha-methyl-4-(2-thienylcarbonyl)-, 2-(4-(2-Thienylcarbonyl)phenyl)propanoic acid, DSSTox_CID_25469, DSSTox_RID_80900, DSSTox_GSID_45469, 2-(4-(thiophene-2-carbonyl)phenyl)propanoic acid, (R)-(Thien-2-ylcarbonyl)propionic acid, SR-05000001776, (-)-alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid, Suprofeno, p-(2-thenoyl)hydratropic acid, racemic suprofen, suprofen RS, TN762, NCGC00016846-01, Prestwick_131, CAS-40828-46-4, Suprofen [USAN:USP:INN:BAN:JAN], (+/-)-Suprofen, Spectrum_001157, Profenal;Topalgic;Suprol, AC1Q1LGM, (.+/-.)-Suprofen, (S)-2-(4-(Thien-2-ylcarbonyl)phenyl)butyric acid, Prestwick0_000816, Prestwick1_000816, Prestwick2_000816, Prestwick3_000816, Spectrum2_001430, Spectrum3_000928, Spectrum4_001027, Spectrum5_001103, D07BPS, Epitope ID:131797, R25061, AC1L1K6E, SCHEMBL23792, BSPBio_000711, KBioGR_001553, KBioSS_001637, MLS002154015, DivK1c_000476, SPECTRUM1501161, SPBio_001540, SPBio_002632, 4-(2-Thenoyl)hydratropic acid, BPBio1_000783, GTPL7298, Suprofen, >=98% (HPLC), DTXSID5045469, CTK8G3285, HMS501H18, KBio1_000476, KBio2_001637, KBio2_004205, KBio2_006773, KBio3_001936, MolPort-001-791-811, NINDS_000476, HMS1570D13, HMS1921L19, HMS2092J07, HMS2097D13, HMS2232O08, HMS3372B18, HMS3651O17, HMS3714D13, para-(2-thenoyl) hydratropic acid, Pharmakon1600-01501161, a-(p-thenoylphenyl) propionic acid, KS-00001F6S, (+)-p-(2-thenoyl)hydratropic acid, (-)-p-(2-thenoyl)hydratropic acid, Tox21_110643, BDBM50090676, CCG-38977, NSC757876, s1761, AKOS004909426, Tox21_110643_1, AC-4551, API0003240, DB00870, NSC-303611, NSC-757876, IDI1_000476, NCGC00094916-01, NCGC00094916-02, NCGC00094916-03, NCGC00094916-06, AN-11896, AS-15879, BC202116, CC-34617, LS-76363, R227, SC-16436, SMR001233343, AB0018061, AB2000277, LS-124867, AB00052231, FT-0630615, C07320, D00452, AB00052231_08, (.+/-.)-2-(p-(2-Thenoyl)phenyl)propionic acid, 2-[4-(2-Thienylcarbonyl)phenyl]propanoic acid #, 828S464, C-16251, SR-05000001776-1, SR-05000001776-3, 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid, 2-{4-[(thiophen-2-yl)carbonyl]phenyl}propanoic acid, Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)-, BRD-A34006693-001-04-8, BRD-A34006693-001-07-1, .alpha.-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid, Suprofen, United States Pharmacopeia (USP) Reference Standard

ID: 1360

InChIKey: MDMWHKZANMNXTF-UHFFFAOYSA-N
SMILES: CC1=C(C(=C(N1)C)C(=O)OC)C(=O)C2=CC=CC=C2CC3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3423
synonyms found at PubChem are:
FPL 64176, FPL-64176, 120934-96-5, FPL64176, UNII-UU89L306PO, Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate, UU89L306PO, CHEBI:249982, Methyl 2,5-dimethyl-4-(2-(phenylmethyl)benzoyl)-1H-pyrrole-3-carboxylate, 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid methyl ester, 1H-Pyrrole-3-carboxylic acid, 2,5-dimethyl-4-(2-(phenylmethyl)benzoyl)-, methyl ester, 4-(2-Benzyl-benzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester, Methyl-2,5-dimethyl-4-(2-(phenylmethyl)benzoyl)-1H-pyrrole-3-carboxylate, 1H-Pyrrole-3-carboxylicacid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester, 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxlic acid methyl ester, SR-01000075316, methyl 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate, Tocris-1403, Lopac-F-131, AC1L1FWH, AC1Q5ZNH, D06XTT, Lopac0_000548, BSPBio_001345, MLS000860055, CHEMBL93655, ACMC-20d698, GTPL2518, SCHEMBL1938827, ZINC5085, CTK4B2101, DTXSID40153064, MDMWHKZANMNXTF-UHFFFAOYSA-N, MolPort-003-941-354, HMS1791D07, HMS1989D07, HMS2233J20, HMS3261N17, HMS3267H04, HMS3370C19, HMS3402D07, Tox21_500548, MFCD00274043, AKOS024456577, API0008371, CCG-204638, LP00548, NCGC00015427-01, NCGC00015427-02, NCGC00015427-03, NCGC00015427-04, NCGC00015427-05, NCGC00015427-06, NCGC00015427-07, NCGC00015427-08, NCGC00015427-09, NCGC00025147-01, NCGC00025147-02, NCGC00025147-03, NCGC00025147-04, NCGC00025147-05, NCGC00025147-06, NCGC00025147-07, NCGC00261233-01, SMR000326913, LS-186945, LS-187593, RT-013049, B6723, EU-0100548, F-131, FPL 64176, >=98% (HPLC), powder, C13759, J-004414, SR-01000075316-1, SR-01000075316-3, BRD-K78959463-001-02-5, BRD-K78959463-001-05-8, 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid, methyl ester

ID: 1361

InChIKey: MDNWOSOZYLHTCG-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3037
synonyms found at PubChem are:
Dichlorophen, dichlorophene, 97-23-4, Dichlorofen, Dichlorphen, 2,2'-Methylenebis(4-chlorophenol), Didroxan, Didroxane, Trivex, Anthiphen, Antiphen, Cordocel, Dicestal, Difentan, Embephen, Panacide, Prevental, Taeniatol, Teniathane, Teniatol, Teniotol, Vermithana, Antifen, Halenol, Hyosan, Korium, Palacel, Parabis, Dichlorophen B, Dichlorophene 10, Dichloorfeen, Gingivit, Wespuril, Gefir, Fungicide M, DDDM, Plath-Lyse, Fungicide GM, Preventol GD, Preventol GDC, Diphenthane 70, Bis(5-chloro-2-hydroxyphenyl)methane, Sandocide, Super mosstox, Di-phentane-70, Bis(chlorohydroxyphenyl)methane, Dichlorophenum, Diclorofeno, 2,2'-Dihydroxy-5,5'-dichlorodiphenylmethane, Bis(2-hydroxy-5-chlorophenyl)methane, Giv Gard G 4-40, Di-(5-chloro-2-hydroxyphenyl)methane, Phenol, 2,2'-methylenebis[4-chloro-, Bis-2-hydroxy-5-chlorfenylmethan, Sindar G 4, Dichlorofen [Czech], Dichloorfeen [Dutch], Caswell No. 563, Bis(5-chlor-2-hydroxyphenyl)-methan, 5,5'-Dichloro-2,2'-dihydroxydiphenylmethane, Methanedichlorofen, O,O-Metilen-bis(4-cloro-fenolo), DDM (VAN), UNII-T1J0JOU64O, Diclorofeno [INN-Spanish], Dichlorophene [INN-French], Dichlorophene [ISO-French], Dichlorophenum [INN-Latin], G-4 Technical, C13H10Cl2O2, Dichlorophen [INN:BAN:DCF], 4,4'-Dichloro-2,2'-methylenediphenol, CCRIS 6060, 1322-43-6, G 4 (VAN), G-4 Pure, HSDB 6033, ((Dihydroxydichloro)diphenyl)methane, Dichlorophen [BSI:ISO], EINECS 202-567-1, NSC 38642, 2,2'-Methylenebis-(4-chlorophenol), 2,2'-Methylene-bis (4-chlorophenol), EPA Pesticide Chemical Code 055001, Phenol, 2,2'-methylenebis(4-chloro-, BRN 1884514, T1J0JOU64O, Bis-2-hydroxy-5-chlorfenylmethan [Czech], CHEMBL33845, AI3-02370, MLS000069468, O,O-Methyleen-bis(4-chloorfenol) [Dutch], O,O-Metilen-bis(4-cloro-fenolo) [Italian], G 4, G-4, 4-chloro-2-(5-chloro-2-hydroxybenzyl)phenol, CHEBI:34689, Bis(5-chlor-2-hydroxyphenyl)-methan [German], MDNWOSOZYLHTCG-UHFFFAOYSA-N, NSC38642, 2,2'-Methylenebis[4-chlorophenol], O,O-Methyleen-bis-(4-chloorfenol), 2,2'-methanediylbis(4-chlorophenol), Dichlorofen (Czech), 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol, NCGC00091325-05, SMR000059095, DSSTox_CID_1824, DSSTox_RID_76351, DSSTox_GSID_21824, 2,5'-dichlorodiphenylmethane, 5,2'-dihydroxydiphenylmethane, W-100114, 4-chloro-2-[(5-chloro-2-hydroxy-phenyl)methyl]phenol, WLN: QR DG B1R BQ EG, Phenol,2'-methylenebis[4-chloro-, [(Dihydroxydichloro)diphenyl]methane, CAS-97-23-4, diclorofen, Algafen, Anthipen, Nuophene, Westpuril, Fungicide fx, Difent*n, Acticide DDM, Diphentane 70, o,o-Methyleen-bis(4-chloorfenol), 2,2'-methylene-bis(4-chlorophenol), Cuniphen (Salt/Mix), Phenol, 2,2'-methylenebis(4-chloro)-, Spectrum_000762, Opera_ID_1730, Spectrum2_001214, Spectrum3_001405, Spectrum4_000390, Spectrum5_001519, SCHEMBL18052, BSPBio_003050, KBioGR_000919, KBioSS_001242, MLS001076530, BIDD:ER0237, DivK1c_000460, SPECTRUM1500626, SPBio_001028, AC1L1F15, DTXSID6021824, Ecco MP 2004 (Salt/Mix), CTK4B7817, HMS501G22, KBio1_000460, KBio2_001242, KBio2_003810, KBio2_006378, KBio3_002270, ZINC56435, MolPort-001-762-146, NINDS_000460, 2,2-Methylenebis(4-chlorophenol), HMS1921M03, HMS2230H06, HMS3373O17, KUC106446N, KUC112931N, Pharmakon1600-01500626, NSC39467, ZX-AT020226, Tox21_111112, Tox21_201429, Tox21_303013, BDBM50303912, CCG-39772, MFCD00002322, NSC-38642, NSC-39467, NSC757391, SBB058814, 2,2''-methylenebis(4-chlorophenol), AKOS015917706, bis(2-hydroxy-5-chlorophenyl)-methane, Tox21_111112_1, 2,2'-Methylene-bis(4-chloro-phenol), CS-3867, KSC-19-050, LS-2023, MCULE-2962145672, NSC-757391, OR22200, bis-(5-chloro-2-hydroxyphenyl)-methane, IDI1_000460, KS-0000171Z, QTL1_000030, NCGC00091325-01, NCGC00091325-03, NCGC00091325-04, NCGC00091325-06, NCGC00091325-07, NCGC00091325-09, NCGC00256543-01, NCGC00258980-01, AC-10330, AK176082, AN-42827, AS-12817, HY-12638, SC-16330, ZB001639, KSC-336-005-1, SBI-0051563.P002, KB-190366, Bis(5-chloro-2-hydroxyphenyl)methane, 95%, FT-0609137, FT-0739351, M0213, ST50826029, C14292, 3,3''-dichloro-6,6''-dihydroxydiphenylmethane, AB00052130_15, Dichlorophene, PESTANAL(R), analytical standard, SR-01000721928, I14-9454, SR-01000721928-3, Bis(5-chloro-2-hydroxyphenyl)methane, technical grade, 90%, 1135443-66-1, 8017-86-5, ethyl 1-[3-(4-ethoxycarbonyl-2,3-dioxo-pyrrolidin-1-yl)propyl]-4,5-dioxo-pyrrolidine-3-carboxylate

ID: 1362

InChIKey: MECHNRXZTMCUDQ-RKHKHRCZSA-N
SMILES: C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5280793
synonyms found at PubChem are:
ergocalciferol, Calciferol, VITAMIN D2, Viosterol, Oleovitamin D2, Ercalciol, Ergorone, Detalup, Condocaps, Crystallina, Deltalin, Fortodyl, Mulsiferol, Radsterin, Sterogyl, Condol, Deratol, Diactol, Ertron, Geltabs, Ostelin, Daral, Novovitamin-D, Divit urto, D-Tracetten, Hi-Deratol, 50-14-6, Calciferon 2, Dee-Ronal, Vitavel-D, Dee-Ron, De-rat concentrate, Vio-D, Rodine C, Activated ergosterol, Calciferolum, Hyperkil, Rodinec, Ergocalciferolum, Mina D2, Radiostol, Haliver, D-Arthin, Davitin, Drisdol, Metadee, Mykostin, (+)-Vitamin D2, Decaps, Infron, Shock-ferol, Viosterol in Oil, Davitamon D, Dee-Osterol, Geltabs Vitamin D, Dee-Roual, Buco-D, Radstein, Ergocalciferolo [DCIT], Vitamina D2, UNII-VS041H42XC, Ergocalciferols, Vitamin D2 (Ergocalciferol), Ergocalciferolum [INN-Latin], Shock-ferol sterogyl, HSDB 819, C28H44O, Irradiated ergosta-5,7,22-trien-3-beta-ol, Oleovitamin D, Synthetic, EINECS 200-014-9, Synthetic Vitamin D, NSC 62792, Ergocalciferolo, Condacaps, Viostdrol, Crtron, 9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol, Oleovitamin D, VS041H42XC, Uvesterol-D, VitaminD2, CHEBI:28934, vitamin d-2, (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol, Ergosterol activated, Ergosterol irradiated, Irradiated ergosterol, Sorex C.R., 9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol, DSSTox_CID_233, (3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol, (3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol, DSSTox_RID_75449, DSSTox_GSID_20233, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol, Ergocalciferol [INN:BAN:JAN], Calciferol (TN), Disdrol, Drisdol (TN), Sorex C.R, 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-, Ergosterol, irradiated, SMR000857106, Doral [Vitamin Derivative], Osteil, delta-Tracetten, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol, delta-Arthin, beta-ol, Uvesterol D, (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol, 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3.beta.,5Z,7E,22E)-, ergocalciferol oil, CAS-50-14-6, NCGC00166307-01, Prestwick_554, Vio D, Ergocalciferol [USP:INN:BAN:JAN], AC1NQXLH, PubChem16654, Prestwick3_000420, bmse000510, 7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87, SCHEMBL3420, CHEMBL1536, BSPBio_000380, Ergocalciferol (JP17/USP), MLS001332467, MLS001332468, BPBio1_000418, MEGxm0_000466, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol, DTXSID5020233, ACon1_002187, (3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol, MECHNRXZTMCUDQ-RKHKHRCZSA-N, MolPort-001-740-057, HMS2096C22, HMS2230E20, ACT02622, CS-M1019, Cyclohexanol, 4-methylene-3-((2E)-2-((1R,3aS,7aR)-octahydro-7a-methyl-1-((1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl)-4H-inden-4-ylidene)ethylidene)-, (1S,3Z)-, Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S,3Z)-, ZINC4629876, Tox21_112404, Tox21_202348, Tox21_302752, LMST03010001, MFCD00166988, s4035, AKOS022185284, DB00153, LS-3228, Ergocalciferol, Sigma Reference Standard, NCGC00166307-02, NCGC00166307-03, NCGC00256529-01, NCGC00259897-01, AJ-84249, AS-11649, Ergocalciferol (D2), analytical standard, HY-76542, Irradiated ergosta-5,7,22-trien-3beta-ol, Vitamin D2 Ergocalciferol 400,000 IU/g, Ergocalciferol, 40,000,000 USP units/g, 7067-EP2305662A1, C05441, D00187, 166V988, Q-201930, 9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol, Ergocalciferol, >=98.0% (sum of enantiomers, HPLC), 22-tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol, Vitamin D2 solution, 100 mug/mL in ethanol, 98% (CP), (5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol, Ergocalciferol, European Pharmacopoeia (EP) Reference Standard, Ergocalciferol, United States Pharmacopeia (USP) Reference Standard, Ergocalciferol (Vitamin D2), Pharmaceutical Secondary Standard; Certified Reference Material, Ergocalciferol for system suitability, EuropePharmacopoeia (EP) Reference Standard, Vitamin D2 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol, 1384584-60-4, 31316-19-5, 4-methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol, 7489-18-1, 8017-28-5, Cycloheanol, 4-methylene-3-(2-(tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene)ethylidene)-

ID: 1363

InChIKey: MEDVHSNRBPAIPU-XMOZQXTISA-N
SMILES: C[C@@H]1C[C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)COC(=O)C)O)C)O)OC(=O)CC5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3034821
synonyms found at PubChem are:
12-DEOXYPHORBOL 13-PHENYLACETATE 20-ACETATE, 12-Deoxyphorbolphenylacetate-20-acetate, DOPPA, 54662-30-5, 12-Deoxyphorbol-13-phenylacetate-20-acetate, 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one, 1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-decahydro-4a-beta,7b-alpha,9a-alpha-trihydroxy-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl-, 3-acetate 9a-phenylacetate, Benzeneacetic acid ,(1aR,1bS,4aR,7aS,7bR,8R,9aS)-3-((acetyloxy)methyl)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulen-9a-yl ester, AC1MHY9M, 12-DPPAA, CHEMBL1395147, SCHEMBL15423126, MEDVHSNRBPAIPU-XMOZQXTISA-N, dPPA, >=98% (HPLC), ZINC17654636, AKOS032945971, CCG-208193, NCGC00163537-01, LS-58487, SR-05000002352, SR-05000002352-2, (acetoxymethyl-dihydroxy-tetramethyl-oxo-[?]yl) 2-phenylacetate

ID: 1364

InChIKey: METKIMKYRPQLGS-GFCCVEGCSA-N
SMILES: CC(C)NC[C@H](COC1=CC=C(C=C1)CC(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 180559
synonyms found at PubChem are:
(R)-(+)-Atenolol, (R)-Atenolol, 56715-13-0, (+)-Atenolol, R(+)-Atenolol, UNII-YG132I00WY, R-(+)-Atenolol, Atenolol, (+)-, YG132I00WY, CHEBI:55352, (R)-2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, GEO-02767, DSSTox_CID_25753, DSSTox_RID_81097, DSSTox_GSID_45753, J-200025, 2-(4-(2-Hydroxy-3-(Isopropylamino)propoxy)phenyl)ethanamide, 2-[4-({(2R)2-hydroxy-3-[(propan-2-yl)amino]propyl}oxy)phenyl]acetamide, SMR000326747, SR-01000075276, Prenormin, Totamol, Vasaten, Atenix, 2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide, 2-{4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide, NCGC00093636-03, 2TN, CAS-56715-13-0, (+)-(R)-Atenolol, (R)-( )-Atenolol, Prestwick0_000953, Prestwick1_000953, Prestwick2_000953, Prestwick3_000536, AC1L47EF, AC1Q1Q9R, (R)-(+)-Atenolol HCl, Lopac0_000146, SCHEMBL18120, BSPBio_000551, MLS001332497, MLS001332498, MLS002154070, BIDD:GT0478, SPBio_003095, (+)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, BPBio1_000607, CHEMBL1230004, DTXSID0045753, ZINC14007, (R)-(+)-Atenolol, 99%, MolPort-001-828-300, HMS1570P08, HMS2096L13, HMS2235G14, HMS3713L13, Tox21_111211, MFCD00074917, AKOS017343045, Tox21_111211_1, CCG-204241, DB06987, NCGC00015007-14, NCGC00093636-04, NCGC00093636-05, AJ-08370, A-142, AB00513974, EU-0100146, FT-0662315, Z1861, AB00513974_06, I05-2985, SR-01000075276-1, SR-01000075276-2, BRD-K68075732-001-03-5, UNII-50VV3VW0TI component METKIMKYRPQLGS-GFCCVEGCSA-N, Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (R)-

ID: 1365

InChIKey: METKIMKYRPQLGS-LBPRGKRZSA-N
SMILES: CC(C)NC[C@@H](COC1=CC=C(C=C1)CC(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 175540
synonyms found at PubChem are:
Esatenolol, (S)-Atenolol, (S)-(-)-Atenolol, S-Atenolol, 93379-54-5, (-)-Atenolol, S(-)-Atenolol, Esatenolol [INN], UNII-DPF757BOSR, S-(-)-Atenolol, S-(-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide, DPF757BOSR, (S)-4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide, 2-(p-((2S)-2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, CHEBI:31556, GEO-02804, Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-, W-200527, (-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 2-[4-({(2S)2-hydroxy-3-[(propan-2-yl)amino]propyl}oxy)phenyl]acetamide, SR-01000597666, NCGC00093636-03, CAS-56715-13-0, (S)(-)-atenolol, (S)-()-Atenolol, Tocris-0387, Tocris-0393, Esatenolol (JAN/INN), Lopac-A-142, Lopac-A-143, Prestwick0_000536, Prestwick1_000536, Prestwick2_000536, Prestwick3_000953, Lopac-A-7655, AC1L41KJ, SCHEMBL4363, Lopac0_000156, BSPBio_000946, MLS002153864, (S)-(-)-Atenolol, powder, SPBio_002472, (S)-(-)-Atenolol 99%, BPBio1_001042, CHEMBL343633, CTK8G3008, (S)-(-)-Atenolol, 99%, DTXSID10239405, METKIMKYRPQLGS-LBPRGKRZSA-N, MolPort-002-507-840, HMS2097P08, HMS2235B16, HMS3260O14, HMS3266K19, HMS3714P08, ZINC113415, Tox21_500156, BG0071, MFCD00074918, AKOS015894675, API0000928, CCG-204251, LP00156, NCGC00015007-01, NCGC00015007-02, NCGC00015007-03, NCGC00015007-04, NCGC00015007-05, NCGC00015007-12, NCGC00016880-01, NCGC00016880-02, NCGC00016880-03, NCGC00016880-04, NCGC00016880-05, NCGC00016880-06, NCGC00016880-07, NCGC00024566-01, NCGC00024570-01, NCGC00024570-02, NCGC00024570-03, NCGC00024570-04, NCGC00093636-01, NCGC00093636-02, NCGC00260841-01, AJ-11432, AN-51044, LS-28558, SMR000326748, CAS-93379-54-5, A-143, AB00513856, B6289, EU-0100156, FT-0662316, V1672, D01471, I05-2986, SR-01000597666-1, SR-01000597666-3, BRD-K44993696-001-03-2, BRD-K44993696-001-05-7, UNII-50VV3VW0TI component METKIMKYRPQLGS-LBPRGKRZSA-N, (S)-2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, 2-[4-[(2S)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide, 2-[4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide, 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, (S)-(-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide

ID: 1366

InChIKey: MEZZCSHVIGVWFI-UHFFFAOYSA-N
SMILES: COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 8569
synonyms found at PubChem are:
dioxybenzone, 131-53-3, 2,2'-DIHYDROXY-4-METHOXYBENZOPHENONE, Dioxybenzon, Benzophenone-8, Advastab 47, Cyasorb UV 24, Spectra-sorb UV 24, (2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone, Methanone, (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-, Cyasorb UV 24 Light Absorber, UF 2, Dioxibenzonum, UV 24, Dioxybenzonum [INN-Latin], Dioxibenzona [INN-Spanish], UNII-B762XZ551X, CCRIS 6231, Benzophenone, 2,2'-dihydroxy-4-methoxy-, EINECS 205-026-8, NSC 56769, NSC-56769, BRN 2055461, AI3-25363, CHEBI:34208, MEZZCSHVIGVWFI-UHFFFAOYSA-N, B762XZ551X, NSC56769, 2-(2-hydroxybenzoyl)-5-methoxyphenol, (2-hydroxy-4-methoxyphenyl)-(2-hydroxyphenyl)methanone, 2,2'-dihydroxy-4-methoxy benzophenone, NCGC00016393-01, CAS-131-53-3, DSSTox_CID_2403, DSSTox_RID_76574, DSSTox_GSID_22403, W-108331, (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone, Dioxibenzona, Dioxybenzonum, 2,2 inverted exclamation marka-Dihydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxyphenyl 2-hydroxyphenyl ketone, SR-05000001610, Dioxybenzone [USAN:INN], Dioxybenzone [USAN:USP:INN], Spectro-sorb UV 24, Spectra-Sorb UV-24, Spectrum_000978, Prestwick0_000898, Prestwick1_000898, Prestwick2_000898, Prestwick3_000898, Spectrum2_001032, Spectrum3_000399, Spectrum4_000519, Spectrum5_000913, Dioxybenzone (USP/INN), ACMC-209bn4, AC1L1R9J, SCHEMBL15894, BSPBio_000716, BSPBio_002217, KBioGR_001097, KBioSS_001458, MLS002154056, BIDD:ER0352, SPECTRUM1500255, SPBio_001243, SPBio_002925, BPBio1_000788, Jsp001908, CHEMBL1326877, DTXSID3022403, Dioxybenzone, analytical standard, KBio2_001458, KBio2_004026, KBio2_006594, KBio3_001437, ZINC37293, component of Solaquin (Salt/Mix), MolPort-001-760-067, AM720, HMS1570D18, HMS1920I04, HMS2091O12, HMS2097D18, HMS2235J06, HMS3371G16, HMS3714D18, Pharmakon1600-01500255, HY-B0966, ZX-AT029395, Tox21_110417, Tox21_200993, ANW-19358, CCG-40196, LS-741, NSC756742, s4607, SBB057333, 2-2'-Dihydroxy-4-methoxybenzophenone, AKOS015856203, Benzophenone,2'-dihydroxy-4-methoxy-, Tox21_110417_1, 2,2'-dihydroxy-4-methoxy-benzophenone, 2,2'-dihydroxy-4-methoxybenzo-phenone, 2,2\'-Dihydroxy-4-methoxybenzophenone, CS-4451, KS-5318, MCULE-2204733956, NSC-756742, NCGC00016393-02, NCGC00016393-03, NCGC00016393-04, NCGC00016393-07, NCGC00094657-01, NCGC00094657-02, NCGC00258546-01, AJ-08744, AK-57636, AN-23057, CC-06485, K820, SMR001233373, ST033388, ZB001030, SBI-0051353.P003, AX8064469, KB-105159, KB-163860, ST2414188, TC-108103, TL8000746, 2,2'-Dihydroxy-4-methoxybenzophenone, 98%, AB00051973, D0586, FT-0609243, C14283, D03853, AB00051973_08, A806277, C-34297, I01-3097, J-506801, SR-05000001610-1, SR-05000001610-3, BRD-K22193694-001-05-2, BRD-K22193694-001-08-6, (2-hydroxyphenyl)-(4-methoxy-2-oxidanyl-phenyl)methanone, S4607 2,2 inverted exclamation marka-Dihydroxy-4-methoxyb, Dioxybenzone, United States Pharmacopeia (USP) Reference Standard, 186100-79-8

ID: 1367

InChIKey: MFOUDYKPLGXPGO-UHFFFAOYSA-N
SMILES: CC(C)N(C1=CC=CC=C1)C(=O)CCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4931
synonyms found at PubChem are:
propachlor, 1918-16-7, 2-Chloro-N-isopropyl-N-phenylacetamide, Niticid, 2-Chloro-N-isopropylacetanilide, Propachlore, Bexton 4L, Nitacid, Satecid, Bexton, Prolex, Ramrod, Kartex A, Acilid, Ramrod 65, N-Isopropyl-2-chloroacetanilide, N-Isopropyl-alpha-chloroacetanilide, 2-Chloro-N-(1-methylethyl)-N-phenylacetamide, Chloressigsaeure-N-isopropylanilid, alpha-Chloro-N-isopropylacetanilide, Acetamide, 2-chloro-N-(1-methylethyl)-N-phenyl-, Acetanilide, 2-chloro-N-isopropyl-, Caswell No. 194, Propachlor [BSI:ISO], CP 31393, Propachlore [ISO-French], Ramrod 20G, HSDB 1200, EINECS 217-638-2, UNII-015443A483, EPA Pesticide Chemical Code 019101, BRN 2103903, 2-chloro-N-phenyl-N-propan-2-ylacetamide, AI3-51503, Chloressigsaeure-N-isopropylanilid [German], 2-chloro-N-phenyl-N-(propan-2-yl)acetamide, CHEBI:19503, alpha-chloro-N-isopropylacetanilid, MFOUDYKPLGXPGO-UHFFFAOYSA-N, DSSTox_CID_4274, DSSTox_RID_77351, DSSTox_GSID_24274, Propachlor, analytical standard, 015443A483, CAS-1918-16-7, Albrass, Muharicid, Ramrod flowable, Ramrod-atrazine, n-isopropyl-a-chloroacetanilide, Tripart sentinel, Spectrum_001885, SpecPlus_000506, AC1Q1PXK, Spectrum2_001842, Spectrum3_000843, Spectrum4_000683, Spectrum5_002002, AC1L1J9A, Ramrod flowable (Salt/Mix), SCHEMBL65571, BSPBio_002425, KBioGR_001145, KBioSS_002415, SPECTRUM330052, MLS002207036, DivK1c_006602, SPBio_001624, 2-Chloro-N-(1-methylethyl)-N-phenylacetamide (9CI), CHEMBL1394829, DTXSID4024274, KBio1_001546, KBio2_002409, KBio2_004977, KBio2_007545, KBio3_001925, MolPort-002-365-679, N-methylethyl-N-chloroacidobenzene, N-isopropyl-N-phenylchloroacetamide, BCP16676, ZINC2039117, Tox21_201734, Tox21_303036, CCG-39380, SBB079583, STL281680, .alpha.-Chloro-N-isopropylacetanilide, N-Isopropyl-.alpha.-Chloroacetanilide, AKOS001031317, MCULE-5126926361, NE11193, Propachlor 10 microg/mL in Cyclohexane, 2-Chloro-N-isopropyl-N-phenyl-acetamide, NCGC00094539-01, NCGC00094539-02, NCGC00094539-03, NCGC00094539-04, NCGC00094539-05, NCGC00094539-06, NCGC00257041-01, NCGC00259283-01, Propachlor 100 microg/mL in Cyclohexane, AC-19975, AJ-33145, AN-50100, CJ-32221, KB-83400, LS-10570, SMR000855773, UPCMLD0ENAT0505-1085:001, 2-chloro-N-(methylethyl)-N-phenylacetamide, DB-044776, Propachlor, PESTANAL(R), analytical standard, 2-chloranyl-N-phenyl-N-propan-2-yl-ethanamide, C18759, 918P167, A813527, SR-01000004720, J-012400, SR-01000004720-1, BRD-K50343025-001-02-5, F0017-0379, 63704-81-4

ID: 1368

InChIKey: MFVJXLPANKSLLD-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=CC=C4)C5=CC=C(C=C5)F)CC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3012
synonyms found at PubChem are:
diacylglycerol kinase inhibitor i, 93076-89-2, R59022, R 59-022, R 59022, UNII-PF550QIT3I, PF550QIT3I, R-59 022, 5h-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-, 6-(2-(4-((4-Fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo(3,2-a)pyrimidine-5-one, R-59-022, 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-((4-fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-, 6-{2-{4-[(p-Fluorophenyl)phenylmethylene]-1-piperidinyl}ethyl}-7-methyl-5H-thiazolo(3,2-a)pyrimidine-5-one, SR-01000075608, Tocris-2194, Lopac-D-5919, AC1L1EZ5, AC1Q4NH1, Lopac0_000401, REGID_for_CID_3012, MLS000028485, SCHEMBL316891, CHEMBL259388, CHEBI:92958, CTK5H2078, DTXSID20239254, MolPort-003-941-007, HMS2234P12, HMS3268B04, ZINC3872275, BS0156, HSCI1_000342, MFCD00055114, AKOS024456981, CCG-204494, LP00107, Diacylglycerol Kinase Inhibitor I, solid, NCGC00015357-01, NCGC00015357-02, NCGC00015357-03, NCGC00015357-04, NCGC00015357-05, NCGC00015357-06, NCGC00021479-02, SMR000058437, LS-186830, LS-187493, B6967, D 5919, MLS-0090818.0001, R-59022, SR-01000075608-1, SR-01000075608-3, BRD-K54665485-001-01-2, 6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-fluorophenyl)-phenylmethylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-fluorophenyl)phenyl- methylene]-1-piperidinyl]ethyl]-7-methyl- 5H-thiazolo-[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-fluorophenyl)phenyl-methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5hthiazolo[3,2-a]pyrimidin-5-one

ID: 1369

InChIKey: MFYSYFVPBJMHGN-ZPOLXVRWSA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 222786
synonyms found at PubChem are:
cortisone, 53-06-5, Andreson, Cortisal, Cortisate, Cortistal, Cortivite, Cortogen, Cortone, Kendall's compound E, Adrenalex, Reichstein's substance FA, Reichstein Fa, Wintersteiner's compound F, 11-Dehydro-17-hydroxycorticosterone, 17-Hydroxy-11-dehydrocorticosterone, Cortandren, Cortisona, Cortison, Cortisone [INN:BAN], 4-Pregnene-17alpha,21-diol-3,11,20-trione, Cortisonum [INN-Latin], 17alpha-Hydroxy-11-dehydrocorticosterone, Cortisona [INN-Spanish], 17alpha,21-Dihydroxypregn-4-ene-3,11,20-trione, Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, NSC 9703, Kendall's compound, [3H]-cortisone, Prestwick_132, UNII-V27W9254FZ, EINECS 200-162-4, 17,21-Dihydroxypregn-4-ene-3,11,20-trione, KE, Pregn-4-en-17alpha,21-diol-3,11,20-trione, 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione, delta(sup4)-pregnene-17alpha,21-diol-3,11,20-trione, AI3-52938, MLS000028540, CHEBI:16962, [3H]cortisone, NSC9703, MFYSYFVPBJMHGN-ZPOLXVRWSA-N, V27W9254FZ, SMR000058334, 17.alpha.-Hydroxy-11-dehydrocorticosterone, DSSTox_CID_2857, DSSTox_RID_76760, DSSTox_GSID_22857, (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione, Cortisonum, Kendall's Compound E., (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,17-dione, Kortison, CAS-53-06-5, Cortisone (TN), Cortisone (INN), NCGC00095935-01, Kendalls Compound E, Corlin (Salt/Mix), Cortelan (Salt/Mix), Ricortex (Salt/Mix), (non-d)Cortisone-d2, Cortadren (Salt/Mix), Scheroson (Salt/Mix), Cortisone, >=98%, Opera_ID_541, Reichsteins Substance Fa, AC1Q5HIV, Prestwick0_000273, Prestwick1_000273, Prestwick2_000273, Prestwick3_000273, Spectrum5_002051, bmse000663, D0IX6I, AC1L5C2T, SCHEMBL4888, CHEMBL1499, Lopac0_000240, BSPBio_000146, MLS001076142, MLS001424269, MLS002207137, 17.alpha.,11,20-trione, SPBio_002365, BPBio1_000162, GTPL5171, DTXSID5022857, BDBM13739, CTK8F8789, Cortisone 0.1 mg/ml in Methanol, MolPort-002-529-087, HMS1568H08, HMS2052A21, HMS2095H08, HMS2235P19, HMS3260P21, HMS3712H08, NSC-9703, ZINC4083557, Tox21_111539, Tox21_301440, Tox21_500240, LMST02030090, MFCD00003610, AKOS015840096, AKOS015894868, Tox21_111539_1, ACN-053277, API0002117, CCG-101143, CS-5097, LP00240, NC00393, 4-Pregnene-17.alpha.,11,20-trione, NCGC00023939-03, NCGC00023939-04, NCGC00023939-05, NCGC00023939-06, NCGC00023939-07, NCGC00023939-08, NCGC00023939-09, NCGC00023939-11, NCGC00255108-01, NCGC00260925-01, Pregn-4-en-17.alpha.,11,20-trione, AS-11686, CPD000058334, HY-17461, LS-55002, NCI60_042165, SAM001246882, SC-46937, EU-0100240, 2708-EP2269977A2, 2708-EP2272834A1, 2708-EP2292228A1, 2708-EP2295411A1, 2708-EP2298747A1, 2708-EP2301929A1, 2708-EP2301935A1, 2708-EP2305674A1, 2708-EP2308851A1, 2708-EP2311811A1, 2708-EP2314585A1, C 2755, C00762, D07749, Pregn-4-ene-3,20-trione, 17,21-dihydroxy-, 10841-EP2280008A2, 10841-EP2298767A1, 10841-EP2301536A1, 10841-EP2301538A1, 10841-EP2311455A1, 10841-EP2314587A1, 10841-EP2316452A1, .delta.(sup4)-pregnene-17.alpha.,11,20-trione, 4-Pregnene-17.alpha.,21-diol-3,11,20-trione, SR-01000000094, Delta4-Pregnene-17, 21-diol-3, 11, 20-trione, Pregn-4-en-17.alpha.,21-diol-3,11,20-trione, SR-01000000094-3, W-105776, 17.alpha.,21-Dihydroxy-4-pregnene-3,11,20-trione, BRD-K43736954-001-03-3, Cortisone, certified reference material, TraceCERT(R), Delta(4)-pregnene-17alpha,21-diol-3,11,20-trione, WLN: L E5 B666 CV OV MUTJ A1 E1 FV1Q FQ, .DELTA.4-pregnene-17.alpha.,21-diol-3,11,20-trione, 17.alpha.,21.beta.-Dihydroxypregn-4-ene-3,11,20-trione, Kendall's Compound E; 4-Pregnene-17alpha,21-diol-3,11,20-trione; Reichstein's Substance Fa

ID: 1370

InChIKey: MFZWMTSUNYWVBU-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC1=C2C(=C(C=C1)CO)SC3=CC=CC=C3C2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3634
synonyms found at PubChem are:
hycanthone, Hycanthon, 3105-97-3, Lucanthone metabolite, Hicantona, Hycanthonum, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, WIN 24933, Hycanthone [USAN:INN], UNII-2BXX5EVN2A, Hicantona [INN-Spanish], Hycanthonum [INN-Latin], 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one, CCRIS 957, Etrenol, EINECS 221-463-7, NSC134434, 2BXX5EVN2A, 1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one, NSC 134434, NSC 142982, WIN 24,933, BRN 1402722, 1-{[2-(Diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one, SMR000058861, CHEMBL22077, MLS000069828, MLS001076079, C20H24N2O2S, CHEBI:52768, 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, 9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-(hydroxymethyl)-, NSC-134434, NCGC00016622-02, CAS-3105-97-3, DSSTox_CID_3128, 1-[(2-[DIETHYLAMINO]ETHYL)AMINO]-4-[HYDROXYMETHYL]-9H-THIOXANTHEN-9-ONE, DSSTox_RID_76885, DSSTox_GSID_23128, 1-[[2-(Diethylamino)ethyl]amino]-4-(hydroxymethyl)-9H-thioxanthen-9-one, Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-(hydroxymethyl)-, SR-01000721922, 1-[[2-(Diethylamino)ethyl]amino]-4-(hydroxymethyl)thioxanthen-9-one, Prestwick_698, Etrenol (Salt/Mix), Spectrum_001601, Opera_ID_669, AC1L1GDE, Prestwick0_000355, Prestwick1_000355, Spectrum2_000678, Spectrum3_001578, Spectrum4_000181, KBioGR_000721, KBioSS_002081, BIDD:GT0491, DivK1c_000480, SCHEMBL314809, SPECTRUM1503239, SPBio_000775, SPBio_002370, Hycanthone mesylate (Salt/Mix), DTXSID9023128, CTK6E8370, HMS501H22, KBio1_000480, KBio2_002081, KBio2_004649, KBio2_007217, KBio3_002616, MFZWMTSUNYWVBU-UHFFFAOYSA-N, NINDS_000480, HMS1569G11, HMS1922M03, HMS2092P10, HMS2096G11, HMS2232H20, HMS3370G12, HMS3713G11, Pharmakon1600-01503239, HY-B1099, ZINC3830916, Tox21_110531, BDBM50066721, CCG-40023, NSC758434, WIN-24933, AKOS027378728, Tox21_110531_1, CS-4690, LS-1169, NSC-758434, NCGC00016622-01, NCGC00016622-03, NCGC00016622-04, NCGC00016622-05, NCGC00016622-08, NCGC00095028-01, NCGC00095028-02, NCGC00178285-01, NCGC00178285-02, DS-12960, NCI60_000765, NCI60_000937, SBI-0051798.P002, AB00052334, FT-0759391, WLN: T C666 BS IVJ D1Q GM2N2&2, D00541, AB00052334_15, C-55216, SR-01000721922-2, SR-01000721922-4, SR-01000721922-5, BRD-K50406511-001-06-2, 1-(2-(diethylamino)ethylamino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9h-thioxanthen-9-on, Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)- (8CI)

ID: 1371

InChIKey: MGCCHNLNRBULBU-WZTVWXICSA-N
SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 39212
synonyms found at PubChem are:
FLUNIXIN MEGLUMINE, 42461-84-7, Flunixin meglumin, Banamine, finadyne, Flumeglumine, Flunixin-S, Sch 14714 meglumine, Flunixin N-methylglucanine, Flunixin (meglumine), Banamine (Veterinary), UNII-8Y3JK0JW3U, Sch-14714 meglumine, EINECS 255-836-0, 8Y3JK0JW3U, CHEBI:76144, 1-Deoxy-1-(methylamino)-D-glucitol 2-(2-methyl-3-(perfluoromethyl)anilino)nicotinate, 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid meglumine salt, 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-Trifluoro-2,3-xylidino)nicotinic acid compound with 1-deoxy-1-(methylamino)-D-glucitol (1:1), 1-Deoxy-1-(methylamino)-D-glucitol 2-[2-methyl-3-(perfluoromethyl)anilino]nicotinate, 2-((2-Methyl-3-(trifluoromethyl)-phenyl)amino)-3-pyridinecarboxylic acid with meglumine compounded, 3-Pyridinecarboxylic acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1), D-Glucitol, 1-deoxy-1-(methylamino)-, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylate (salt), SMR000875279, SR-05000001901, Flunixin Meglumine [USAN], Equileve, Ilium Flunixil, Flunixin meglumine [USAN:USP], (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid, C14H11F3N2O2.C7H17NO5, PubChem15394, Flunixin meglumine (USP), Flunixin N-Methylglucamine, Banamine [vetarynary] (TN), SCHEMBL43691, BSPBio_002558, MLS001333159, MLS002153985, SPECTRUM1505113, AC1L21A7, CHEMBL1733447, CTK8F9789, C21H28F3N3O7, MGCCHNLNRBULBU-WZTVWXICSA-N, MolPort-003-666-584, HMS2093I10, HMS2234K05, Pharmakon1600-01505113, HY-B0386, NIH 10250, NSC759583, s2108, Flunixin meglumine, >=98% (HPLC), AKOS015895954, AC-6012, API0025954, CCG-213338, CS-2460, KS-5126, NSC-759583, KS-000010G2, NCGC00180889-01, 2-((2-methyl-3-(trifluoromethyl)- phenyl)amino)-3-pyridinecarboxylic acid with meglumine compounded, LS-71360, SC-18614, AB2000512, FT-0626443, D04216, K-8817, AB00920714_05, AB00920714_06, 461F847, C-22876, I06-1248, Q-201124, SR-05000001901-1, SR-05000001901-3, Flunixin meglumine, European Pharmacopoeia (EP) Reference Standard, Flunixin meglumine, United States Pharmacopeia (USP) Reference Standard, 2-(2-Methyl-3-trifluoromethylanilino)nicotinic Acid N-Methyl-D-glucamine Salt, Flunixin Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material, (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-(2-methyl-3-(trifluoromethyl)phenylamino)nicotinate, (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid, 1-deoxy-1-(methylazaniumyl)-D-glucitol 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinate, 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid 1-Deoxy-1-(methylamino)-D-glucitol, 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic acid--1-deoxy-1-(methylamino)-D-glucitol (1/1)

ID: 1372

InChIKey: MGCQZNBCJBRZDT-UHFFFAOYSA-N
SMILES: COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 18340
synonyms found at PubChem are:
MIDODRINE HYDROCHLORIDE, Midodrine HCL, Pro-Amatine, 3092-17-9, Midodrine (hydrochloride), ProAmatine, 43218-56-0, Amatine, Hipertan, Metligene, Midamine, Gutron, (+-)-Midodrine hydrochloride, St. Peter 224, Alphamine, A 4020 Linz, EINECS 256-148-3, TS 701, CHEBI:31847, A-4020 Linz, (+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride, (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride, 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide monohydrochloride, Midodrine hydrochloride [USAN], 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride, Midodrine hydrochloride [USAN:JAN], Pro-Amatine (TN), 2-Amino-N-(2-(2,5-dimethoxyphenyl)-2-hyyroxyethyl)acetamide monohydrochloride, Acetamide, 2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)-, hydrochloride, DSSTox_CID_27493, DSSTox_RID_82380, DSSTox_GSID_47493, C12H18N2O4.HCl, Q-201404, [+/-]-1-[2,5-Dimethoxyphenyl]-2-glycinamidoethanol, 2-Amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide monohydrochloride, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide hydrochloride, rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide hydrochloride, Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-, monohydrochloride, SMR000058833, Midodrine hydrochloride (JAN/USAN), ( -)-Midodrin hydrochloride, (+-)-Midodrin hydrochloride, ( -)-Midodrine hydrochloride, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide hydrochloride, Prestwick_625, Midodrine hydrochloride [USAN:USP:JAN], NCGC00016620-01, CAS-3092-17-9, AC1L2BU9, SCHEMBL41463, St 1085 [as the base], C12H19ClN2O4, MLS001332567, MLS001332568, MLS002154233, SPECTRUM1503257, ST-1085 [As The Base], CHEMBL1200461, DTXSID1047493, CTK1D6108, MGCQZNBCJBRZDT-UHFFFAOYSA-N, MolPort-003-666-473, s120, HMS1568H03, HMS1922O03, Pharmakon1600-01503257, Tox21_110529, Tox21_302723, CCG-39323, HY-12749A, NSC758429, AKOS015895724, Tox21_110529_1, API0001437, API0024416, CS-4689, HS-0099, LS-8042, LS-8052, MCULE-8615039451, NC00573, NSC-758429, VA11298, ACM43218560, NCGC00095311-01, NCGC00178238-05, NCGC00256810-01, CPD000058833, SAM002564219, TL8002369, FT-0603627, FT-0701302, ST51037351, D01307, 092M179, 218M560, A820652, I06-0865, SR-05000001847-3, Midodrine hydrochloride, analytical standard, for drug analysis, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide hydrochloride, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide, chloride, Midodrine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 2-azanyl-N-[2-(2,5-dimethoxyphenyl)-2-oxidanyl-ethyl]ethanamide hydrochloride, Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-, monohydrochloride, (+-)-, Acetamide, 2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)-, monohydrochloride, (+-)-, 2- degrees +/->>u-N-[2-(2,5- paragraph signthorn(1/4)xNo>>u+/-(1/2)>>u)-2-oCOO>>u]OOo pound degrees ., AKOS026750147

ID: 1373

InChIKey: MGFYJNMOZGSGMU-RMKNXTFCSA-N
SMILES: COC1=CC(=C(C=C1C/C=C/C2=CC=CC=C2)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5458526
synonyms found at PubChem are:
VIOLASTYRENE, NSC269122, 19034-96-9, AC1NUQHV, Spectrum5_000311, BSPBio_001757, SPECTRUM201078, 4-cinnamyl-2,5-dimethoxyphenol, CHEMBL1354529, SCHEMBL11866392, DTXSID60420008, ZINC1560397, CCG-38401, NSC-269122, SDCCGMLS-0066464.P001, NCGC00095496-01, NCGC00095496-02, SR-05000002520, 2,5-dimethoxy-4-[(E)-3-phenylprop-2-enyl]phenol, SR-05000002520-1, 2,5-dimethoxy-4-[(2E)-3-phenylprop-2-en-1-yl]phenol

ID: 1374

InChIKey: MGNNYKWRWHQLCR-RDYQINQZSA-N
SMILES: C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4)[O-].Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6419978
synonyms found at PubChem are:
6106-81-6, UNII-7E0GR5N4K8, Scopolamin-N-oxide hydrobromide, Scopolamine N-oxide HBr, Hyoscine N-oxide hydrobromide, Scopolamine N-oxide hydrobromide, 7E0GR5N4K8, AMINOXYSCOPOLAMINE HYDROBROMIDE, Scopolamine, N-oxide, hydrobromide, DSSTox_CID_25101, DSSTox_RID_80670, DSSTox_GSID_45101, Scopolamine aminoxide hydrobromide, Hyoscine N-oxide hydrobomide, SR-01000841223, HSDB 6105, Prestwick_557, EINECS 228-066-8, NSC 61807, SCOPOLAMINE, N-OXIDE,HYDROBROMIDE, NCGC00016669-01, CAS-6106-81-6, MLS002154241, CHEMBL1731448, DTXSID2045101, HMS1568P05, (-)Scopolamine N-oxide hydrobromide, Tox21_110036, Tox21_110555, CCG-220232, NCGC00013723-01, 1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-, (-)-tropate (ester), 8-oxide, hydrobromide, Benzeneacetic acid, alpha-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2,4))non-7-yl ester, N-oxide, hydrobromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-, SMR001233510, SR-01000841223-5, I14-101666, (?S)-?-(Hydroxymethyl)benzeneacetic acid (1?,2?,4?,5?,7?)-9-methyl-3-oxa-9-oxido-9-azatricyclo[3.3.1.02,4]non-7-yl ester hydrobromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-9-Methyl-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl (hydroxymethyl)phenylacetate N-oxide hydrobromide, 1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-, (-)-tropate (ester), 8-oxide, hydrobromide (8CI), Benzeneacetic acid, alpha-(hydroxymethyl)-, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-9-oxido-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl ester, hydrobromide (1:1), (alphaS)-, Benzeneacetic acid, alpha-(hydroxymethyl)-, (1alpha,2beta,4beta,5alpha,7beta)-9-methyl-9-oxido-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl ester, hydrobromide, (alphaS)-, Benzeneacetic acid, alpha-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl ester, N-oxide, hydrobromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))- (9CI)

ID: 1375

InChIKey: MHDTWYNWOBNGFA-UHFFFAOYSA-N
SMILES: C1CN(CCC12C(=O)N(CN2C3=CC=CC=C3)CCC4=CC=C(C=C4)N=C=S)CCCC(=O)C5=CC=C(C=C5)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16219721
synonyms found at PubChem are:
NIPS hydrochloride, N-(p-Isothiocyanatophenethyl)spiperone hydrochloride, 135261-88-0, NIPS HCL, CHEMBL2447972, N-140, SR-01000076039, SR-01000076039-1

ID: 1376

InChIKey: MHFRGQHAERHWKZ-HHHXNRCGSA-N
SMILES: CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6918215
synonyms found at PubChem are:
ET-18-OCH3, 77286-66-9, 1-Octadecyl-2-methyl-sn-glycero-3-phosphocholine, UNII-LZ198HY9OE, LZ198HY9OE, 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine, CHEBI:78653, 70641-51-9, NCGC00093851-01, PC(O-18:0/O-1:0), C27H58NO6P, 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-, (R)-edelfosine, Edelfosine, (R)-, (+)-(R)-Edelfosine, AC1OCF5Z, 2-O-methyl PAF C-18, DSSTox_CID_25766, DSSTox_RID_81108, TLC-ELL-12, DSSTox_GSID_45766, SCHEMBL436257, BML3-F02, CHEMBL107514, DTXSID9045766, BDBM86730, MHFRGQHAERHWKZ-HHHXNRCGSA-N, MolPort-003-941-244, HMS1361G03, HMS1791G03, HMS1989G03, HMS3261E22, HMS3402G03, HMS3648P18, Tox21_111225, Tox21_500430, (+)-(R)-ET-18-OMe, 1310AH, AKOS024457387, CCG-204522, LP00430, (+)-(R)-ET-18-OCH3, NCGC00093851-02, NCGC00093851-03, NCGC00093851-04, NCGC00093851-05, NCGC00093851-06, NCGC00261115-01, 1-OCTADECYL-2-METHYLGLYCERO-3 PC, CAS-70641-51-9, CAS_77286-66-9, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, EU-0100430, FT-0773005, 1-Stearyl-2-methyl-sn-glycero-3-phosphocholine, E 1779, 1-O-Octadecyl-2-O-methyl-sn-glyceryl-3-phosphorylcholine, UNII-1Y6SNA8L5S component MHFRGQHAERHWKZ-HHHXNRCGSA-N, (2R)-2-methoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate, [(2R)-2-methoxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate, (7R)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4-oxide, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-N,N,N-trimethyl-,inner salt,4-oxide

ID: 1377

InChIKey: MHPIZTURFVSLTJ-UHFFFAOYSA-N
SMILES: CS(=O)(=O)O.C1=CC=C(C=C1)NC(=NC(=O)C2=C(N=C(C(=N2)Cl)N)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6604148
synonyms found at PubChem are:
Phenamil methanesulfonate, 1161-94-0, Phenamil methanesulfonate salt, 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt, MLS002172443, SMR000326941, NCGC00016186-01, Lopac-P-203, Phenamil (methanesulfonate), MLS000860083, CHEMBL1256775, MolPort-003-959-179, HMS2234A15, HMS3263G17, HMS3370J10, Tox21_500998, MFCD00274070, Phenamil methanesulfonate salt, solid, Phenamil methanesulfonate (free base), AKOS024457592, API0008627, CCG-222302, LP00998, NCGC00016186-02, NCGC00094293-01, NCGC00261683-01, B7390, EU-0100998, SR-01000075343, J-013264, SR-01000075343-1, 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]-pyrazinecarboxamide methansulfonate

ID: 1378

InChIKey: MIBSKSYCRFWIRU-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 104920
synonyms found at PubChem are:
67469-78-7, Vanoxerine dihydrochloride, GBR 12909 dihydrochloride, GBR-12909 dihydrochloride, Vanoxerine hydrochloride, GBR-12909, Vanoxeamine, UNII-MWO1IP03EV, MWO1IP03EV, Vanoxerine dihydrochloride(GBR12909), GBR12909 dihydrochloride, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride, 1-(2-[bis(4-Fluorophenyl)methoxy]ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride, I 893, I-893, CHEBI:64086, 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine dihydrochloride, NCGC00015300-05, 1-(2 (Bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine di-hcl, DSSTox_CID_22570, DSSTox_RID_80049, DSSTox_GSID_42570, J-502921, CHEMBL543876, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride, 1-[2-[bis(4-Fluorophenyl)methoxy]ethyl]-4-[3-phenylpropyl]piperazine dihydrochloride, Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)-, dihydrochloride, SR-01000075379, CAS-67469-78-7, D-052, Prestwick_664, Vanoxerinedihydrochloride, 1-(2-bis-[4-FLUOROPHENYL]-METHOXYETHYL)-4-(3-PHENYL-2-PROPYL)PIPERAZINE, AC1L2XPW, AC1Q3AML, Vanoxenine dihydrochloride, Vanoxerine(dihydrochloride), D00WLO, Vanoxerine (dihydrochloride), SCHEMBL725103, Vanoxerine(GBR-12909) /, DTXSID1042570, MIBSKSYCRFWIRU-UHFFFAOYSA-N, MolPort-003-983-576, HMS1569M13, KS-00000T9Q, Tox21_110125, Tox21_500446, ABP000311, BN0220, MFCD00055193, AKOS024458037, Tox21_110125_1, AN-3656, CCG-220386, CCG-221750, LP00446, RL04564, NCGC00015300-10, NCGC00093862-01, NCGC00261131-01, 4CA-1310, AK186951, AT-37030, KB-81427, LS-107633, EU-0100446, FT-0722032, Q-9382, 469G787, A1-04930, SR-01000075379-1, SR-01000075379-3, SR-01000075379-6, GBR 12909 dihydrochloride, solid, >=98% (HPLC), 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride, 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazinediium dichloride

ID: 1379

InChIKey: MIDVMFJWRNXXDK-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=CC=C1OC(=O)C2=CC=C(C=C2)OC)OC(=O)C3=CC=C(C=C3)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10916784
synonyms found at PubChem are:
Bis(4-methoxybenzoic acid)2-acetyl-m-phenylene ester

ID: 1380

InChIKey: MIJKZXWOOXIEEU-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1C(=O)O)O)C)OC(=O)C2=C(C(=C(C=C2C)OC)C)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 94870
synonyms found at PubChem are:
Diffractaic acid, Dirbizomic acid, Dirhizomic acid, DIFFRACTOIC ACID, DIFFRACTANIC ACID, 436-32-8, Diffractic acid, NSC 5901, NSC 685595, BRN 2915070, NSC5901, NSC685595, NSC-685595, Benzoic acid, 2,4-dimethoxy-3,6-dimethyl-, 4-carboxy-3-hydroxy-2,5-dimethylphenyl ester, beta-Resorcylic acid, 3,6-dimethyl-, 4-(2,4-dimethoxy-3,6-dimethylbenzoate), Diffractasaure, DiffracticAcid, Dirhizonic acid, DIFFRATIC ACID, Spectrum_000043, SpecPlus_000832, AC1Q5ULR, Spectrum2_000730, Spectrum3_001103, Spectrum4_001934, Spectrum5_000723, AC1L3T2R, BSPBio_002806, KBioGR_002309, KBioSS_000423, 3-10-00-01544 (Beilstein Handbook Reference), MLS001049104, DivK1c_006928, SPECTRUM1504118, SPBio_000660, CHEMBL367741, SCHEMBL3459615, KBio1_001872, KBio2_000423, KBio2_002991, KBio2_005559, KBio3_002026, DTXSID40195883, CHEBI:107634, MolPort-002-514-208, NSC-5901, ZINC1687273, ACM436328, CCG-39676, AKOS015969704, 4-[(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,6-dimethylbenzoic acid, NCGC00095683-01, NCGC00095683-02, SMR000386936, LS-143441, A827187, SR-01000758212, SR-01000758212-2, BRD-K51370144-001-02-3, BRD-K51370144-001-06-4, 4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid, 4-(2,4-dimethoxy-3,6-dimethyl-phenyl)carbonyloxy-3,6-dimethyl-2-oxidanyl-benzoic acid, 4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid, 4-(2,4-Dimethoxy-3,6-dimethylphenylcarbonyloxy)-2-hydroxy-3,6-dimethylbenzoic acid, 4-[(2,4-dimethoxy-3,6-dimethylphenyl)-oxomethoxy]-2-hydroxy-3,6-dimethylbenzoic acid

ID: 1381

InChIKey: MIJYXULNPSFWEK-GTOFXWBISA-N
SMILES: C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10494
synonyms found at PubChem are:
OLEANOLIC ACID, Oleanic acid, 508-02-1, Caryophyllin, Astrantiagenin C, Giganteumgenin C, Virgaureagenin B, 3beta-Hydroxyolean-12-en-28-oic acid, UNII-6SMK8R7TGJ, CCRIS 6493, 3-beta-Hydroxyolean-12-en-28-oic acid, OLEANOLIC_ACID, (3-beta)-3-Hydroxyolean-12-en-28-oic acid, EINECS 208-081-6, NSC114945, 6SMK8R7TGJ, NSC-114945, CHEBI:37659, Olean-12-en-28-oic acid, 3-hydroxy-, (3beta)-, oleonolic acid, (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid, NSC 114945, Olean-12-en-28-oic acid, 3-hydroxy-, (3-beta)-, (2S,5S,10S,18S,1R,14R,15R,20R)-18-hydroxy-1,2,8,8,15,19,19-heptamethylpentacyc lo[12.8.0.0<2,11>.0<5,10>.0<15,20>]docos-11-ene-5-carboxylic acid, (4aS,5S,6aS,6bR,8R,8aR,10S,12aR,12bR,14bS)-10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid, (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid, 3-Beta-Hydroxy-Olean-12-En-28-Oicaci, SMR000445561, 3beta-Hydroxyolean-12-en-28-oate, CHEMBL168, Oleanoic Acid Hydrate, Olean-12-en-28-oic acid, 3.beta.-hydroxy-, AC1L1VBP, D0SJ2Q, Oleanolic acid, >=97%, SCHEMBL71070, MLS000697656, MLS002207133, GTPL3306, AOB5588, DTXSID50858790, MIJYXULNPSFWEK-GTOFXWBISA-N, MolPort-004-955-261, HMS2232D15, Oleanolic acid (OA)(Compound 1), Oleanolic acid, analytical standard, HY-N0156, ZINC3785416, BDBM50346601, MFCD00064914, 3-beta-Hydroxyolean-12-en-28-oate, 3beta-hydroxy-Olean-12-en-28-oate, AKOS015951416, AC-8026, AN-8439, CCG-208530, CS-3800, LMPR0106150004, VA11435, 3.beta.-hydroxy-Olean-12-en-28-oate, 3beta-hydroxy-Olean-12-en-28-oic acid, 4CN-0935, AS-35338, BC203005, LS-98296, SC-17259, ST057162, (3-beta)-3-Hydroxyolean-12-en-28-oate, (3?)-3-Hydroxyolean-12-en-28-oic acid, 3.beta.-hydroxy-Olean-12-en-28-oic acid, AB1009824, Olean-12-en-28-oic acid, 3beta-hydroxy-, FT-0082748, N1826, Olean-12-en-28-oic acid, 3-beta-hydroxy-, ST24041804, (3.beta.)-3-hydroxy-Olean-12-en-28-oate, C17148, (3.beta.)-3-hydroxy-Olean-12-en-28-oic acid, (3.beta.)-3-beta-hydroxy-Olean-12-en-28-oate, 508O021, Olean-12-en-28-oic acid, 3-beta-hydroxy- (8CI), Olean-12-en-28-oic acid, 3beta-hydroxy- (8CI), Q-100572, (3.beta.)-3-beta-hydroxy-Olean-12-en-28-oic acid, Oleanolic acid, primary pharmaceutical reference standard, C7EE6ACC-7175-4947-B524-FF8479525DA1, Oleanolic acid, European Pharmacopoeia (EP) Reference Standard, Oleanolic acid, United States Pharmacopeia (USP) Reference Standard

ID: 1382

InChIKey: MJIHNNLFOKEZEW-UHFFFAOYSA-N
SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3883
synonyms found at PubChem are:
lansoprazole, 103577-45-3, Prevacid, Bamalite, Monolitum, Lansoprazol, Agopton, Limpidex, Ogastro, Lanzor, Opiren, Prevacid SoluTab, Lanzopral, Takepron, Zoton, Lansoprazolum, Lanproton, Lansopep, Lasoprol, Mesactol, Aprazol, Blason, Ketian, Lancid, Lanston, Prezal, Ulpax, Lanz, Pro Ulco, Compraz, Ilsatec, Prosogan, Suprecid, Dakar, Promp, Zoprol, AG-1749, Prevacid Iv, Ogast, Lanzol-30, AG 1749, lanzoprazole, Lansoprazol [INN-Spanish], Lansoprazolum [INN-Latin], Lansox, Lanzo, Prevacid NapraPAC, Prevacid 24HR, Prevacid I.V., A-65006, TAK 390MR, Lanzol, Lanzul, Lansoprazole [USAN:BAN:INN], PrevOnco, Biuret Gr, Prevacid I.V, Prevacid (TN), CHEBI:6375, HSDB 7204, Biuret Reagent Solution, A 65006, TAK-390MR, BRN 4333393, 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole, MLS000069705, C16H14F3N3O2S, ABT-006, 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole, CG-4801, NCGC00015615-02, CPD000058469, SMR000058469, CAS-103577-45-3, DSSTox_CID_3200, L 8533, MLS-0003247.0001, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)-1H-benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methylsulfinyl]-1H-benzimidazole, DSSTox_RID_76922, DSSTox_GSID_23200, Lansophed, Promeco, 1H-Benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-, 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, 2-[({3-methyl-4-[(2,2,2-trifluoroethyl)oxy]pyridin-2-yl}methyl)sulfinyl]-1H-benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole, 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole, 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylsulfinyl]-1H-benzimidazole, 2-[[3-methyl-4-[2,2,2-tris(fluoranyl)ethoxy]pyridin-2-yl]methylsulfinyl]-1H-benzimidazole, 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole, 2-({3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl} sulphinylbenzimidazole;2-({3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl} sulphinylbenzimidazole, SR-01000000169, TAP Brand of Lansoprazole, Abbot Brand of Lansoprazole, Vinas Brand of Lansoprazole, Wyeth Brand of Lansoprazole, TAK390MR, Salvar Brand of Lansoprazole, Takeda Brand of Lansoprazole, Lanfast, Hoechst Brand of Lansoprazole, Hormona Brand of Lansoprazole, Lapraz, Lederle Brand of Lansoprazole, Promeco Brand of Lansoprazole, Almirall Brand of Lansoprazole, Biuret reagent, Tecnobio Brand of Lansoprazole, KS-1075, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole, 2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl}-1H-benzimidazole, Lansoprazole,(S), Takepron (TN), Agopton (TN), Lansoprazole [USAN:USP:INN:BAN], Lansox (TN), LANSAPRAZOLE, Ogast (TN), PubChem16834, Spectrum_001580, Prevacid Delayed Release, Opera_ID_1676, Prestwick0_001072, Prestwick1_001072, Prestwick2_001072, Prestwick3_001072, Spectrum2_000444, Spectrum3_000295, Spectrum4_000856, Spectrum5_001521, Lopac-L-8533, CHEMBL480, D0M4HV, AC1L1GX8, cid_3883, Lopac0_000709, SCHEMBL22365, BSPBio_001084, BSPBio_001830, KBioGR_001491, KBioSS_002060, MLS000759405, MLS001074170, MLS001424235, BIDD:GT0006, DivK1c_000920, SPECTRUM1503926, Lansoprazole (JAN/USP/INN), Lansoprazole, 98% 500mg, SPBio_000488, SPBio_002992, BPBio1_001194, GTPL7208, DTXSID4023200, BDBM47032, CTK8F0500, HMS502N22, KBio1_000920, KBio2_002060, KBio2_004628, KBio2_007196, KBio3_001330, KS-00000VHO, Lansoprazole (JP17/USP/INN), MJIHNNLFOKEZEW-UHFFFAOYSA-N, MolPort-003-666-508, NINDS_000920, HMS1571G06, HMS1922M04, HMS2052F05, HMS2093M07, HMS2098G06, HMS2234B10, HMS3262M19, HMS3264E12, HMS3269D15, HMS3371E21, HMS3394F05, HMS3654J17, HMS3715G06, Pharmakon1600-01503926, Pharmakon1600-01504282, ACT03358, BCP22331, EBD14854, Tox21_110184, Tox21_301023, Tox21_500709, BBL029072, BDBM50070208, BG0232, CCG-39952, CL0035, GP5308, MFCD00866873, NSC758638, NSC758710, s1354, STK621169, AKOS005554811, Tox21_110184_1, AC-1233, API0005388, CS-1847, DB00448, Lansoprazole, >=98% (TLC), powder, LP00709, MCULE-8446262134, NC00411, NSC-758638, NSC-758710, IDI1_000920, NCGC00015615-01, NCGC00015615-03, NCGC00015615-04, NCGC00015615-05, NCGC00015615-06, NCGC00015615-07, NCGC00015615-08, NCGC00015615-09, NCGC00015615-10, NCGC00015615-11, NCGC00015615-12, NCGC00015615-14, NCGC00015615-15, NCGC00023826-03, NCGC00023826-04, NCGC00023826-05, NCGC00023826-06, NCGC00023826-07, NCGC00254925-01, NCGC00261394-01, AN-15125, BC208317, CC-29843, HY-13662, LS-33080, SAM001246544, SC-15158, SBI-0050687.P003, AB0005100, AB2000063, Prevacid;Prevacid NapraPAC;Prevacid SoluTab, RT-013461, TL8000155, AB00052388, EU-0100709, FT-0082011, FT-0610894, L0233, ST51015040, D00355, AB00052388-17, AB00052388_18, AB00052388_19, 577L453, A800764, C-21097, I06-0018, J-007154, SR-01000000169-2, SR-01000000169-6, SR-01000000169-9, BRD-A49172652-001-05-7, BRD-A49172652-001-13-1, F2173-0222, Lansoprazole, British Pharmacopoeia (BP) Reference Standard, Prevacid, Prevacid NapraPAC, Prevacid SoluTab, Lansoprazole, Lansoprazole, European Pharmacopoeia (EP) Reference Standard, Lansoprazole, United States Pharmacopeia (USP) Reference Standard, (+)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl}sulfinyl)benzimidazol e, 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methane}sulfinyl)-1H-1,3-benzodiazole, 2-[[ [3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoro-ethoxy)-2-pyridinyl]methyl]-sulfinyl]1H-benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]-methyl]sulfinyl]benzimidazole, 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyrid-2-yl]methylsulfinyl]benzimidazole, 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzoimidazole, 2-[3-Methyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzimidazole, 2-[3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-benzimidazole, 2-[3-methyl-4-(2,2,2-trifluoro-ethoxy)pyridin-2-ylmethanesulfinyl]-benzimidazole, 2-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl-methanesulfinyl]-1H-benzimidazole, 2-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-ylmethanesulfinyl]-1H-benzimidazole, Lansoprazole for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 1383

InChIKey: MJKVTPMWOKAVMS-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=C(C(=O)O2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 13650
synonyms found at PubChem are:
3-Hydroxycoumarin, 939-19-5, 3-hydroxy-2H-chromen-2-one, 3-Hydroxy-2-benzopyrone, 3 Hydroxycoumarin, 3-Hydroxy-2H-1-benzopyran-2-one, hydroxycoumarin, 3-hydroxychromen-2-one, UNII-RQX0CMD9PN, 3-Hydroxy-chromen-2-one, RQX0CMD9PN, EINECS 213-355-3, NSC 74691, 2H-1-Benzopyran-2-one, 3-hydroxy-, BRN 0128032, COUMARIN, 3-HYDROXY-, CHEMBL150372, 2H-1-Benzopyran-2-one, hydroxy-, AN-829/40355682, 43070-85-5, 3-hydroxy-coumari, 3-hydroxy-coumarin, NSC74691, hydroxycoumarin, 3-, 3 - Hydroxycoumarin, aurora ka-3736, 2,3-dihydroxycoumarin, Spectrum_000476, SpecPlus_000860, Spectrum2_000805, Spectrum3_001267, Spectrum4_001576, Spectrum5_000232, 2H-1-Benzopyran-2-one, 3-hydroxy- (9CI), hydroxy-2H-chromen-2-one, SCHEMBL76090, BSPBio_002834, KBioGR_002132, KBioSS_000956, SPECTRUM211538, 5-18-01-00376 (Beilstein Handbook Reference), DivK1c_006956, SPBio_000669, AC1L226O, CTK1D2829, KBio1_001900, KBio2_000956, KBio2_003524, KBio2_006092, KBio3_002334, DTXSID50239863, CHEBI:113542, MJKVTPMWOKAVMS-UHFFFAOYSA-N, MolPort-001-770-794, 3-hydroxy-2h-1-benzopyran-2-on, o-Hydroxyphenylpyruvic acid lactone, ZINC336205, ZX-AT008439, 2H-1-Benzopyran-2-one,3-hydroxy-, 3767AF, BDBM50206007, CCG-39664, NSC-74691, OR9103, SBB056328, AKOS015916452, FCH1121318, MCULE-4074896000, SDCCGMLS-0066523.P001, NCGC00095536-01, NCGC00095536-02, NCGC00178445-01, AJ-19764, KB-32192, LS-55208, ZB010813, DB-057448, FT-0633159, ST50331499, C-57780, BRD-K92019075-001-02-0, I14-49948

ID: 1384

InChIKey: MJVAVZPDRWSRRC-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=CC=CC=C2C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4055
synonyms found at PubChem are:
menadione, Vitamin K3, 58-27-5, 2-Methyl-1,4-naphthoquinone, Menaphthone, 2-methylnaphthalene-1,4-dione, 2-Methylnaphthoquinone, Thyloquinone, Kappaxin, Kayquinone, Klottone, Panosine, Kayklot, Kolklot, 2-Methyl-1,4-naphthalenedione, Menaphthon, Menadion, Kanone, Kipca, Aquinone, Kaergona, Kativ-G, Mitenone, Prokayvit, Aquakay, Hemodal, Karcon, Kareon, Kaykot, Koaxin, Mitenon, Synkay, K-Thrombyl, K-Vitan, Kipca-Oil Soluble, Juva-K, Vitamin K2(0), Vitamin K0, Menaquinone 0, 2-Methyl-1,4-naphthochinon, Menadionum, Menaphtone, Vitamin K 3, Memodol, Usaf ek-5185, 1,4-Naphthalenedione, 2-methyl-, 3-Methyl-1,4-naphthoquinone, Methylnaphthoquinone, Kappaxan (VAN), Menadione semiquinone, Menaphthene, Kaynone, Vicasol, 2-Methyl-1,4-naftochinon, 1,4-Naphthoquinone, 2-methyl-, Menadione [USAN:BAN], Menaquinone O, Methyl-1,4-naphthoquinone, NSC 4170, 2-methyl-1,4-dihydronaphthalene-1,4-dione, 2-Methyl-1,4-naftochinon [Czech], UNII-723JX6CXY5, Menadione (USP), Kappaxin (TN), Kipca, oil soluble, 2-Methyl-1,4-naphthochinon [German], NAPHTHOQUINONE, METHYL-, CCRIS 6672, HSDB 3354, C11H8O2, NSC4170, Menadione (Vitamin K3), EINECS 200-372-6, MNQ, CHEMBL590, 2-Methyl-1,4-naphthodione, Methyl-1,4-naphthalenedione, 2-Methyl-1,4-naphthalendione, AI3-14700, MLS000069420, 723JX6CXY5, CHEBI:28869, 2-methyl-1,4-naphthoquinone, 5, MJVAVZPDRWSRRC-UHFFFAOYSA-N, CAS-58-27-5, NCGC00016258-02, SMR000059102, 1,4-Dihydro-2-methylnaphthalene-1,4-dione, Vitamin K3 : 2-Methyl-1,4-naphthoquinone, M0373, DSSTox_CID_1715, DSSTox_RID_76289, DSSTox_GSID_21715, VK3, Q-201350, Menadione [USP:BAN], SR-01000712386, Vitamin-K3, Menadione, 9, Menadione,(S), Menadione (K3), Prestwick_313, Apatone (TN), Menadione, 98%, Menadione, crystalline, Ascorbic acid/menadione, PubChem14596, Spectrum_001228, ACMC-1BCKI, SpecPlus_000191, AC1L1HBA, Opera_ID_1802, Prestwick0_000459, Prestwick1_000459, Prestwick2_000459, Prestwick3_000459, Spectrum2_001194, Spectrum4_000722, Spectrum5_001764, D03GET, D0C3XZ, D0T4ZM, NCIMech_000105, Triglycyl-lysine-vasopressin, AC1Q2HB3, cid_4055, 2-methyl-1,4-napthoquinone, SCHEMBL25970, BSPBio_000538, KBioGR_000984, KBioGR_002527, KBioSS_001708, KBioSS_002535, 2-methyl-1,4 naphthoquinone, 34524-96-4, KSC608C0H, MLS001148443, ARONIS24154, BIDD:ER0556, DivK1c_000080, DivK1c_006287, SPECTRUM1502254, SPBio_001267, SPBio_002477, 3-methyl-1,4-naphthalenedione, BPBio1_000592, ZINC1677, DTXSID4021715, 2-Methyl-[1,4]-naphthoquinone, BDBM24778, CTK5A8103, HMS500D22, KBio1_000080, KBio1_001231, KBio2_001708, KBio2_002527, KBio2_004276, KBio2_005095, KBio2_006844, KBio2_007663, KBio3_003005, WLN: L66 BV EVJ C1, cMAP_000077, MolPort-001-766-699, NINDS_000080, Bio1_000471, Bio1_000960, Bio1_001449, HMS1569K20, HMS1921P06, HMS2092F12, HMS2096K20, HMS2232A09, HMS2234J16, HMS3371M08, HMS3373A12, HMS3655P03, Pharmakon1600-01502254, BB_NC-02319, BCP25699, HY-B0332, NSC-4170, STR01143, ZX-AS004517, ZX-AT006056, Tox21_110334, Tox21_301367, ANW-32906, BBL027351, BG0249, CCG-35354, Menadione (K3), analytical standard, MFCD00001681, NSC758200, s1949, SBB012369, STL377874, AKOS004910447, AKOS025244105, Tox21_110334_1, CS-2374, DB00170, FCH1114831, FS-2556, MCULE-2487773379, NSC-758200, RTR-037165, TRA0064327, IDI1_000080, KS-00000C40, QTL1_000056, BENZOYL CHLORIDE,2,5-DIHYDROXY-, NCGC00016258-01, NCGC00016258-03, NCGC00016258-04, NCGC00016258-06, NCGC00016258-07, NCGC00016258-08, NCGC00094978-01, NCGC00094978-02, NCGC00255225-01, 72060-21-0, AN-23599, BC678083, CC-30201, H500, LS-95653, LS-95654, NCI60_003945, SC-16348, SC-61015, SMR000653532, ST066885, ZB000387, SBI-0051776.P002, AB2000387, KB-173579, Menadione, meets USP testing specifications, TR-037165, FT-0612893, C05377, D02335, Z-3172, 001M681, 1,4-Naphthalenedione, 2-methyl-,radical ion(1-), A831816, C-24481, 1,4-Naphthalenedione, 2-methyl-, radical ion(1-), I14-2821, SR-01000712386-2, SR-01000712386-5, SR-01000712386-6, BRD-K78126613-001-16-0, Vitamin K3: 1,4-Dihydro-1,4-dioxo-2-methylnaphthalene, Menadione, European Pharmacopoeia (EP) Reference Standard, 03AAE1E9-B215-45AF-976C-91E61894A467, Menadione, United States Pharmacopeia (USP) Reference Standard, Menadione, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H

ID: 1385

InChIKey: MKBLHFILKIKSQM-UHFFFAOYSA-N
SMILES: CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 68647
synonyms found at PubChem are:
ONDANSETRON HYDROCHLORIDE, Zofran, 99614-01-4, ONDANSETRON HCl, Emetron, Ondemet, Emeset, Ondansetron (Hydrochloride), SN 307, NSC 665799, ZOFRAN PRESERVATIVE FREE, CPD000469179, 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one monohydrochloride, C18H19N3O.HCl, 9-METHYL-3-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)-2,3-DIHYDRO-1H-CARBAZOL-4(9H)-ONE HYDROCHLORIDE, Q-201515, 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one hydrochloride, 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride, SMR000469179, 99614-02-5 (Parent), 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride, SR-01000763250, Zofran and dextrose in plastic container, PubChem17490, Ondansetron hydrochloride preservative free, AC1Q3ERO, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazol-4-one hydrochloride, AC1L2A5S, OSETRON HYDROCHLORIDE, SCHEMBL41455, MLS001304076, MLS001401397, MLS002222312, Ondemet;Emeset;Emetron;Zofran, SN 307 HYDROCHLORIDE, REGID_for_CID_68647, CHEMBL1201111, CTK8F0270, Ondansetron hydrochloride and dextrose in plastic container, MKBLHFILKIKSQM-UHFFFAOYSA-N, MolPort-003-983-448, GR 38032F HYDROCHLORIDE, HMS1571C18, Ondansetron hydrochloride (Zofran), HY-B0002, Ondansetron hydrochloride and sodium chloride in plastic container, BG0279, NSC665799, s1390, AKOS015889292, AB07046, API0003688, CCG-100852, CCG-221058, CS-1715, GS-3597, H39O049, NC00102, NSC-665799, 9-methyl-3-[(2-methyl-1h-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4h-carbazol-4-onhydrochlorid, AC-12464, BC204680, LS-51879, O739, SAM001246631, AB0016622, AB2000081, RT-014862, TL8000158, O0407, VU0424014-2, A800774, I06-131, I01-1935, I06-0131, SR-01000763250-5, 9-methyl-3-[(2-methyl-1-imidazolyl)methyl]-2,3-dihydro-1H-carbazol-4-one hydrochloride, 110204-46-1, 110707-92-1, 9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride, 9-METHYL-3-(2-METHYL-IMIDAZOL-1-YLMETHYL)-1,2,3,9-TETRAHYDRO-CARBAZOL-4-ONE HYDROCHLORIDE, 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one hydrochloride, MolPort-000-760-516, MCULE-4423935922, FT-0659335

ID: 1386

InChIKey: MKFFGUZYVNDHIH-UHFFFAOYSA-N
SMILES: CC(C)NCC(C1=CC(=CC(=C1)O)O)O.CC(C)NCC(C1=CC(=CC(=C1)O)O)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 441333
synonyms found at PubChem are:
5874-97-5, Metaproterenol sulfate, Orciprenaline sulfate, Metaproterenol hemisulfate salt, Metaproterenol hemisulfate, Alupent (TN), Metaproterenol sulfate, orciprenaline sulfate, EN300-50867, TH-152, DSSTox_CID_25391, DSSTox_RID_80848, DSSTox_GSID_45391, bis(5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol); sulfuric acid, 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol;sulfuric acid, Prestwick_845, Metaproterenol sulphate, AC1L9AZJ, AC1Q7DNI, NCGC00016662-01, CAS-5874-97-5, SCHEMBL41815, Metaproterenol sulfate (USP), Orciprenaline sulfate (JP17), CHEMBL1568057, DTXSID4045391, CTK8A7112, MolPort-003-921-112, HMS1569F11, HMS2096F11, HMS3262C10, HMS3713F11, Tox21_110551, Tox21_500734, MFCD00058303, AKOS015994757, Tox21_110551_1, CCG-220505, CCG-222038, LP00734, MCULE-1763503293, SS-4263, NCGC00015655-09, NCGC00094078-01, NCGC00261419-01, CC-30246, O694, EU-0100734, FT-0628263, D00685, M 2398, 874M975, SR-01000872665, SR-01000872665-1, Z955123630, 5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol hemisulfate, bis(5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol) sulfate, 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol; sulfuric acid, Metaproterenol sulfate, United States Pharmacopeia (USP) Reference Standard, Orciprenaline sulfate, European Pharmacopoeia (EP) Reference Standard, bis(5-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,3-diol); sulfuric acid, Orciprenaline for system suitability, European Pharmacopoeia (EP) Reference Standard, Novasmasol, Orciprenaline sulphate, EINECS 227-539-6, 1-(3,5-Dihydroxyphenyl)-2-(isopropylamino)ethanol sulfate, 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethane sulfate, 3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate, 3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate (2:1), (+-)-3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol sulfate (2:1), 1,3-Benzenediol, 5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, sulfate (2:1) (salt), 1,3-Benzenediol, 5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, sulfate (2:1) salt, 1,3-Benzenediol, 5-(1-hydroxy-2-(1-methylethyl)amino)ethyl-, (+-)-, sulfate (2:1) (salt), Benzyl alcohol, 3,5-dihydroxy-alpha-((isopropylamino)methyl)-, sulfate (2:1) (salt), Metaproterenol sulfate [USAN], Metaproterenol sulfate [USAN:USP], LS-42875

ID: 1387

InChIKey: MKQLKSXQNMNNHU-UHFFFAOYSA-N
SMILES: C=CCCCCCCCCCCCC(CC(CO)O)O.C#CCCCCCCCCCCCC(CC(CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6710748
synonyms found at PubChem are:
KBio3_002327, AVOCATIN B, Spectrum2_001718, Spectrum3_001184, Spectrum4_001579, AC1O8K0V, BSPBio_002827, KBioGR_002138, SPBio_001736, CHEMBL1488138, CCG-38789, SDCCGMLS-0066874.P001, NCGC00095318-01, NCGC00095318-02, heptadec-16-ene-1,2,4-triol; heptadec-16-yne-1,2,4-triol

ID: 1388

InChIKey: MKTZWXWTQQOMSH-OTCZLQCGSA-N
SMILES: C[C@@H](CN1CCC(CC1)CC2=CC=CC=C2)[C@H](C3=CC=C(C=C3)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957690
synonyms found at PubChem are:
Ro 25-6981 hydrochloride, 919289-58-0, Ro 25-6981 hydrochloride hydrate, SR-01000076107, EU-0101082, ro25-6981 hydrochloride, MLS002153317, SCHEMBL9241534, CHEMBL1256726, AOB5642, MolPort-003-959-459, Tox21_501082, CCG-222386, LP01082, Ro-256981, NCGC00094359-01, NCGC00261767-01, SMR001230731, KB-146008, R 7150, SR-01000076107-2, SR-01000076107-3, (alphar,betas)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride, (R-[R*,S*])-alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-peperidinepropanol) hydrochloride, [R-(R*,S*)]-alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate, 169197-02-8

ID: 1389

InChIKey: MKUXAQIIEYXACX-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1COCCO)NC(=NC2=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2022
synonyms found at PubChem are:
acyclovir, Aciclovir, Acycloguanosine, 59277-89-3, Zovirax, Vipral, Virorax, Wellcome-248U, 9-[(2-Hydroxyethoxy)methyl]guanine, Aciclovirum, Activir, Zovir, Aciclovirum [Latin], Aciclovier, Hascovir, Sitavig, Virolex, Avirax, Genvir, Maynar, Zyclir, 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one, Aciclovirum [INN-Latin], W-248-U, 9-(2-Hydroxyethoxy)methylguanine, 9-HYROXYETHOXYMETHYLGUANINE, Acyclovir [USAN], Acyclovir-side chain-2-3H, ACYCLOVIR SODIUM, 9-((2-Hydroxyethoxy)methyl)guanine, Acicloftal, Cargosil, Viropump, AcycloFoam, Alti-Acyclovir, BW-248U, Acyclovir Lauriad, UNII-X4HES1O11F, DRG-0008, Acyclovir (USP), Zovirax (TN), NSC 645011, CCRIS 1953, CHEBI:2453, 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one, Acyclovir (Aciclovir), 2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one, HSDB 6511, EINECS 261-685-1, 9-[(2-Hydroxyethoxy)-methyl]guanine, ACV & Pluronic F-68, 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, X4HES1O11F, Acyclovir & Pluronic F-68, MLS000069633, C8H11N5O3, 9-(2-Hydroxyethoxymethyl)guanine, MKUXAQIIEYXACX-UHFFFAOYSA-N, BW-248-U, BW-248U74, NSC645011, 141294-79-3, AC2, NCGC00015061-02, Zovirax Oral Acyclovir (ACV) Suspension, SMR000058225, 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one, CAS-59277-89-3, 6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-, DSSTox_CID_2556, A 4669, DSSTox_RID_76626, DSSTox_GSID_22556, 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one, 2-amino-9-[(2-hydroxyethoxy)methyl]hydropurin-6-one, 2-amino-9-((2-hydroxyethoxy)methyl)-3H-purin-6(9H)-one, 2-amino-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one, Acic, 2-amino-9-{[(2-hydroxyethyl)oxy]methyl}-1,9-dihydro-6H-purin-6-one, 6H-Purin-6-one,2-amino-1,9-dihydro-9-((2-hydroxyethoxy)mehtyl), Acyclo-V, SR-01000075540, Acyclovir [USAN:USP], Cyclovir, Poviral, Sitavir, Zovirax topical, 2-amino-9-((2-hydroxyethoxy)methyl)-1,9-dihydro-6H-purin-6-one, 2-amino-9-((2-hydroxyethoxy)methyl)-3,9-dihydro-6H-purin-6-one, Prestwick_6, 1pwy, Aciclovir [INN], Acivirax (TN), Cyclovir (TN), Sitavig (TN), Acivir (TN), Herpex (TN), Zovir (TN), iontophoretic acyclovir, PubChem9572, Spectrum_001739, Aciclovir (JAN/INN), Opera_ID_1674, Prestwick0_000086, Prestwick1_000086, Prestwick2_000086, Prestwick3_000086, Spectrum2_001563, Spectrum3_001874, Spectrum4_000225, Spectrum5_001093, Lopac-A-4669, Aciclovir (JP17/INN), B-LF& ACV, CHEMBL184, D0B5MP, D0Y9QQ, AC1L1CR6, Aciclovir tablets (JP17), SCHEMBL3175, Aciclovir granules (JP17), Lopac0_000037, BSPBio_000012, BSPBio_003348, KBioGR_000889, KBioSS_002219, KSC492E1D, ARONIS27002, BIDD:GT0646, DivK1c_000185, SPECTRUM1503603, SPBio_001466, SPBio_001951, BPBio1_000014, GTPL4829, SCHEMBL9828560, 9(2-hydroxyethoxymethyl)guanine, DTXSID1022556, CTK3J2211, HMS500J07, KBio1_000185, KBio2_002219, KBio2_004787, KBio2_007355, KBio3_002850, KS-00000FAT, BW 248U, MolPort-000-768-994, MolPort-001-889-834, MolPort-003-940-063, NINDS_000185, HMS1568A14, HMS1922E08, HMS2090G09, HMS2095A14, HMS2234K21, HMS3259N10, HMS3260G15, HMS3269M15, HMS3372K02, HMS3655C14, HMS3712A14, Pharmakon1600-01503603, BCP11036, EBD48195, ZINC1530555, 9-(2-hydroxyethoxy methyl) guanine, Tox21_110075, Tox21_500037, 69657-51-8 (Na salt), 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-, Aciclovir ophthalmic oinment (JP17), ANW-43941, BBL009642, BDBM50021776, BDBM50103518, CCG-39909, MFCD00057880, NSC758477, s1807, SBB063281, STK796771, STL257059, STL301862, AKOS000656213, AKOS015995680, AKOS022135433, Tox21_110075_1, 9-[(2-Hydroxyethoxy)- methyl]guanine, AC-8068, AN-8358, CS-1353, DB00787, KS-1027, LP00037, MCULE-2703274259, NC00717, NSC-645011, NSC-758477, RP27589, IDI1_000185, KS-000048I2, SMP1_000007, NCGC00015061-01, NCGC00015061-03, NCGC00015061-04, NCGC00015061-05, NCGC00015061-06, NCGC00015061-07, NCGC00015061-08, NCGC00015061-09, NCGC00015061-10, NCGC00015061-12, NCGC00015061-13, NCGC00022426-03, NCGC00093555-01, NCGC00093555-02, NCGC00093555-03, NCGC00093555-04, NCGC00167756-01, NCGC00167756-02, NCGC00260722-01, AJ-26665, BAS 00485787, BC201598, BR-24687, CJ-05206, CPD000058225, HY-17422, SAM002589967, SC-05587, ST024744, Acycloguanosine, >=99% (HPLC), powder, AB0012294, AB0068584, Aciclovir 1.0 mg/ml in Dimethyl Sulfoxide, LS-127209, TL8003779, AM20100442, EU-0100037, FT-0082883, FT-0621607, FT-0657847, 6383-EP2270005A1, 6383-EP2305243A1, 6383-EP2305640A2, 6383-EP2305808A1, 6383-EP2314582A1, 6383-EP2314585A1, 9-[(2-Hydroxyethoxy)-methyl]guanine;Acyclovir, Aciclovir, Acycloguanosine, Zovirax, Acyclovir, C06810, D00222, J10243, M-1904, 32284-EP2281815A1, 32284-EP2301933A1, 32284-EP2311827A1, 277A893, A832236, I01-1122, Q-200591, SR-01000075540-1, SR-01000075540-3, SR-01000075540-5, 2-amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol, 2-azanyl-9-(2-hydroxyethyloxymethyl)-3H-purin-6-one, BRD-K32318651-001-17-9, F2173-0946, Aciclovir, European Pharmacopoeia (EP) Reference Standard, 2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one, Acyclovir, United States Pharmacopeia (USP) Reference Standard, 2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one (ACV), 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one #, Acyclovir, Pharmaceutical Secondary Standard; Certified Reference Material, Aciclovir for peak identification 1, European Pharmacopoeia (EP) Reference Standard, Aciclovir for peak identification 2, European Pharmacopoeia (EP) Reference Standard, Aciclovir for system suitability, European Pharmacopoeia (EP) Reference Standard, Bovine lactoferrin & 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one, InChI=1/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15

ID: 1390

InChIKey: MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES: CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3397
synonyms found at PubChem are:
flutamide, 13311-84-7, Eulexin, Niftolide, Niftholide, NFBA, Drogenil, 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide, niftolid, Flutamidum, Flutamida, Flutamin, Cebatrol, veterinary, Sch 13521, Sch-13521, 4'-Nitro-3'-trifluoromethylisobutyranilide, Eulexine, Chimax, Ham's F-12 medium, Flutamidum [INN-Latin], Flutamida [INN-Spanish], Flutamide USP25, Prostandril, Cebatrol, Odyne, 2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide, Eulexin (TN), Flutamide [USAN:BAN:INN], NSC 215876, Flutamide (Eulexin), CCRIS 7246, Propanamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, UNII-76W6J0943E, C11H11F3N2O3, SCH13521, N-(4-NITRO-3-(TRIFLUOROMETHYL)PHENYL)ISOBUTYRAMIDE, EINECS 236-341-9, CHEMBL806, alpha,alpha,alpha-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide, BRN 2157663, 4-Nitro-3-(trifluoromethyl)isobutyranilide, CHEBI:5132, 4'-Nitro-3'-(trifluoromethyl)isobutyranilide, Propanamide, 2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, MKXKFYHWDHIYRV-UHFFFAOYSA-N, NK-601, 76W6J0943E, NCGC00015452-09, 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide, CPD000058187, 4'-Nitro-3'-trifluoromethylisobutyramilide, CAS-13311-84-7, F0663, F 9397, DSSTox_CID_11121, DSSTox_RID_78899, DSSTox_GSID_32004, Flutandrona, Prostogenat, Cytamid, Flutacell, Flutaplex, Flutexin, Fugerel, N1-[4-nitro-3-(trifluoromethyl)phenyl]-2-methylpropanamide, Oncosal, Prostacur, Prostica, Testotard, Apimid, ApoFlutamide, Fluken, Flulem, Flumid, NovoFlutamide, m-propionotoluidide,alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro, Novo Flutamide, Novo-Flutamide, Apo Flutamide, Apo-Flutamide, Fluta cell, Fluta-cell, m-Propionotoluidide, 2-methyl-4'-nitro-alpha,alpha,alpha-triflouro-, FlutaGRY, PMS Flutamide, PMS-Flutamide, Fluta 1A Pharma, Fluta GRY, Fluta-GRY, 37209-54-4, SMR000058187, m-Propionotoluidide,.alpha.,.alpha.-trifluoro-, SR-01000075888, flutopharm, Flutamid, .alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide, m-Propionotoluidide,.alpha.,.alpha.-trifluoro-2-methyl-4'-nitro-, Flutamide [USAN:USP:INN:BAN], Flutamide,(S), Flutamide(Eulexin), Prestwick_228, ACMC-20hidt, Gry Brand of Flutamide, PubChem13536, Spectrum_001210, 1A Brand of Flutamide, Juta Brand of Flutamide, TAD Brand of Flutamide, InibsaBrand of Flutamide, AC1L1FUE, Essex Brand of Flutamide, Hexal Brand of Flutamide, Ipsen Brand of Flutamide, Flutamide(pubertal study), Prestwick0_000180, Prestwick1_000180, Prestwick2_000180, Prestwick3_000180, Spectrum2_001201, Spectrum3_001421, Spectrum4_000829, Spectrum5_001450, ETHINYL ESTRADIOL), Lopac-F-9397, Apotex Brand of Flutamide, Chiron Brand of Flutamide, Ciclum Brand of Flutamide, Flutamide (AR inhibitor), Lemery Brand of Flutamide, esparma Brand of Flutamide, D0Y0SW, Flutamide (pubertal study), Apogepha Brand of Flutamide, Kendrick Brand of Flutamide, Q Pharm Brand of Flutamide, Q-Pharm Brand of Flutamide, SCHEMBL3934, Schering Brand of Flutamide, Azupharma Brand of Flutamide, Flutamide (JAN/USP/INN), Novopharm Brand of Flutamide, Prasfarma Brand of Flutamide, Lopac0_000557, BSPBio_000079, BSPBio_003122, KBioGR_001377, KBioSS_001690, Alphapharm Brand of Flutamide, Chephasaar Brand of Flutamide, MLS000069634, MLS001065596, MLS002548892, cell pharm Brand of Flutamide, DivK1c_000459, SPECTRUM1500995, SPBio_000982, SPBio_002000, Flutamide (JP17/USP/INN), BPBio1_000087, GTPL6943, Tedec Meiji Brand of Flutamide, DTXSID7032004, Pharmascience Brand of Flutamide, SCHEMBL12932289, CTK4B8363, HMS501G21, KBio1_000459, KBio2_001690, KBio2_004258, KBio2_006826, KBio3_002342, MolPort-001-771-894, NINDS_000459, HMS1568D21, HMS1921O16, HMS2090I18, HMS2092O14, HMS2095D21, HMS2230P19, HMS3259I03, HMS3261P15, HMS3373C12, HMS3655G22, HMS3712D21, Pharmakon1600-01500995, Schering Plough Brand of Flutamide, Schering-Plough Brand of Flutamide, BCP23006, HY-B0022, ZINC3812944, Tox21_110154, Tox21_202169, Tox21_300536, Tox21_500557, AN-025, BDBM50131270, CCG-39105, MFCD00072009, NSC147834, NSC215876, NSC757817, s1908, SBB006930, AKOS001025465, AKOS015994751, AKOS025243203, Eulexin, Flutamin, Drogenil,Flutamide, m-Propionotoluidide, .alpha.,.alpha.,.alpha.-trifluoro-2-methyl-4'-nitro-, Tox21_110154_1, AB02835, CS-2359, DB00499, KS-5091, LP00557, LS-2105, MCULE-7498839065, NC00451, NSC-147834, NSC-215876, NSC-757817, IDI1_000459, KS-00000L22, NCGC00015452-01, NCGC00015452-02, NCGC00015452-03, NCGC00015452-04, NCGC00015452-05, NCGC00015452-06, NCGC00015452-07, NCGC00015452-08, NCGC00015452-10, NCGC00015452-11, NCGC00015452-12, NCGC00015452-13, NCGC00015452-14, NCGC00015452-15, NCGC00015452-16, NCGC00015452-19, NCGC00015452-20, NCGC00091460-01, NCGC00091460-02, NCGC00091460-03, NCGC00091460-04, NCGC00091460-05, NCGC00091460-06, NCGC00091460-07, NCGC00091460-08, NCGC00091460-09, NCGC00254495-01, NCGC00259718-01, NCGC00261242-01, AC-24192, CJ-10770, SAM002264612, SC-12180, ST058409, SBI-0050540.P003, AB0005010, AB1010911, 3'-Trifluoromethyl-4'-Nitro-Isobutyranilide, AB00052188, EU-0100557, FT-0626493, 4''-nitro-3''-trifluoromethylisobutyranilide, C07653, D00586, J10037, K-4175, AB00052188-09, AB00052188_10, AB00052188_11, 311F847, A806562, I01-2470, Q-201131, SR-01000075888-1, SR-01000075888-6, SR-01000075888-7, SR-01000075888-9, BRD-K28307902-001-05-0, Flutamide, certified reference material, TraceCERT(R), Z56755651, a,a,a-Trifluoro-2-methyl-4'-nitro- m-propionotoluidide, Flutamide, European Pharmacopoeia (EP) Reference Standard, 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide #, Flutamide, United States Pharmacopeia (USP) Reference Standard, Propanamide,2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, 2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE, alpha,alpha,alpha-trifluoro-2-methyl-4''-nitro-m-propionotoluidide, m-Propionotoluidide, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-, PUBERTAL FLUTAMIDE STUDY (PUBERTAL STUDIES OF VINCLOZOLIN, .alpha.,.alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide, m-Propionotoluidide, 2-methyl-4'-nitro-.alpha.,.alpha.,.alpha.-trifluoro-, m-Propionotoluidide, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro- (8CI), M-Propionotoluidide, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-(8CI), Flutamide for system suitability, European Pharmacopoeia (EP) Reference Standard, PUBERTAL FLUTAMIDE STUDY (PUBERTAL STUDIES OF VINCLOZOLIN; METHOXYCHLOR; ETHINYL ESTRADIOL)

ID: 1391

InChIKey: MLKXDPUZXIRXEP-MFOYZWKCSA-N
SMILES: CC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1548887
synonyms found at PubChem are:
sulindac, Clinoril, 38194-50-2, Arthrocine, Sulindac sulfoxide, Sulindaco, Sulindacum, Mobilin, Arthrobid, Klinoril, MK 231, Sulindacum [INN-Latin], Sulindaco [INN-Spanish], Aflodac, MK-231, Clinoril (TN), Sulreuma, C20H17FO3S, CCRIS 3305, CHEBI:9352, (Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid, Sulindac [USAN:BAN:INN:JAN], MK231, cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid, (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid, cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid, EINECS 253-819-2, BRN 2951842, Algocetil, Artribid, Citireuma, Clisundac, Imbaral, Reumofil, Sulinol, CHEMBL15770, Sudac, Copal, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-, NCGC00015970-02, Copals, Copal resin, Resin copal, CAS-38194-50-2, Gum copal, DSSTox_CID_3624, S 8139, {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid, 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid, 5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid, DSSTox_RID_77117, DSSTox_GSID_23624, Copal rosin varnish, Chibret, Kenalin, Sulindal, Aclin, cis-Sulindac, Novo Sundac, Novo-Sundac, Nu Sulindac, Nu-Sulindac, Sulindac (Clinoril), Apo Sulin, Apo-Sulin, (Z)-5-Fluoro-2-methyl-1-[[4-(methyl-sulfinyl)phenyl]methylene]-1H-indene-3-acetic acid, 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid, SR-01000075237, Moblilin, (Z)-2-[5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl]acetic Acid, 2-(5-fluoro-2-methyl-1-{[4-(methylsulfinyl)phenyl]methylene}inden-3-yl)acetic acid, 32004-68-5, EINECS 250-893-8, EINECS 256-402-3, Sulindac [USAN:USP:INN:BAN:JAN], Tocris-1707, Merck Brand of Sulindac, AC1LU7GY, Apotex Brand of Sulindac, Chemia Brand of Sulindac, Clinoril;Aflodac;Sulreuma, KendrickBrand of Sulindac, Prestwick3_000073, Spectrum5_001024, Lopac-S-8139, D0Z5IU, Sulindac, >=98.0%, Novopharm Brand of Sulindac, Nu Pharm Brand of Sulindac, Nu-Pharm Brand of Sulindac, SCHEMBL4202, SCHEMBL4203, Sulindac (JAN/USP/INN), Alphapharm Brand of Sulindac, Lopac0_001070, BSPBio_000285, BSPBio_002890, MLS001056554, SPECTRUM1500556, Sulindac (JP17/USP/INN), BPBio1_000315, GTPL5425, DTXSID4023624, CHEBI:93811, HMS501O03, (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid, {(1E)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid, {5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1h-inden-3-yl}acetic acid, 2-[6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid, cMAP_000021, MLKXDPUZXIRXEP-MFOYZWKCSA-N, MolPort-003-666-287, HMS1921C11, HMS2092K15, HMS2095O07, HMS2231N24, HMS3259K06, HMS3263E22, HMS3649P19, HMS3712O07, Pharmakon1600-01500556, (E)-(1)-5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid, [(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfinyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid, HY-B0008, Tox21_110270, Tox21_301418, Tox21_501070, BDBM50012899, BDBM50103504, CCG-39264, NSC757344, s2007, SBB058181, Cahill May Roberts Brand of Sulindac, AKOS015895412, cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidenyl)indene-3-acetic acid, Tox21_110270_1, CS-0569, DB00605, KS-5153, LP01070, Merck Sharp & Dohme Brand of Sulindac, NC00540, NSC-757344, (Z)-(1)-5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-, (1Z)-, IDI1_000601, NCGC00015970-01, NCGC00015970-03, NCGC00015970-04, NCGC00015970-05, NCGC00015970-06, NCGC00015970-07, NCGC00015970-08, NCGC00015970-11, NCGC00025268-01, NCGC00025268-02, NCGC00025268-03, NCGC00094349-01, NCGC00094349-02, NCGC00255143-01, NCGC00261755-01, 49627-22-7, BP-30208, CPD000326718, LS-81610, SAM002554933, SMR000326718, SBI-0051040.P004, Sulindac, meets USP testing specifications, AB2000418, RT-000169, AB00513800, EU-0101070, ST24026687, ST51015123, U0099, 9222-EP2275420A1, 9222-EP2277565A2, 9222-EP2277566A2, 9222-EP2277567A1, 9222-EP2277568A2, 9222-EP2277569A2, 9222-EP2277570A2, 9222-EP2280008A2, 9222-EP2281815A1, 9222-EP2284166A1, 9222-EP2292280A1, 9222-EP2295055A2, 9222-EP2295409A1, 9222-EP2298764A1, 9222-EP2298765A1, 9222-EP2301933A1, 9222-EP2305640A2, 9222-EP2305652A2, 9222-EP2308872A1, 9222-EP2311453A1, 9222-EP2311827A1, 9222-EP2314585A1, 9222-EP2314590A1, 9222-EP2316829A1, C01531, D00120, W-5115, AB00052105-07, AB00052105_08, AB00052105_09, J-008554, J-012337, SR-01000075237-2, SR-01000075237-3, SR-01000075237-5, SR-01000075237-7, BRD-A13946108-001-04-9, BRD-A13946108-001-08-0, SR-01000075237-13, Sulindac, European Pharmacopoeia (EP) Reference Standard, Sulindac, United States Pharmacopeia (USP) Reference Standard, (Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)-benzylidene)-1H-inden-3-yl)acetic acid, (Z)-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidene]-1H-indene-3-acetic Acid, (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)-phenyl]methylene]-1H-indene-3-acetic acid, {(1z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1h-indene-3-yl}acetic acid, 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylene]inden-1-yl]acetic acid, Sulindac|(1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid

ID: 1392

InChIKey: MLRLSLPKGJJDGV-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(C(=O)C2=C(O1)C(=C(C=C2O)O)OC)C3=CC(=C(C(=C3)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5781146
synonyms found at PubChem are:
SPBio_000835, AC1NXHQS, SpecPlus_000141, Spectrum2_000848, DivK1c_006237, KBio1_001181, CCG-40310, 2-ETHOXYCARBONYL-5,7-DIHYDROXY-8,3',4',5'-TETRAMETHOXYISOFLAVONE, ethyl 5,7-dihydroxy-8-methoxy-4-oxo-3-(3,4,5-trimethoxyphenyl)chromene-2-carboxylate

ID: 1393

InChIKey: MMCMKWDIEUZMQB-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1)NC3=C(C=CC=N3)N=C2N4CCN(CC4)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3802
synonyms found at PubChem are:
JL-18, JL 18, 147395-65-1, NCGC00094013-01, CHEMBL63329, 8-methyl-6-(4-methylpiperazin-1-yl)-11h-pyrido[2,3-b][1,4]benzodiazepine, 11H-Pyrido[2,3-b][1,4]benzodiazepine,8-methyl-6-(4-methyl-1-piperazinyl)-, ACMC-20dd8i, Lopac-J-102, AC1L1GQW, AC1Q4UQG, D0G0IQ, Lopac0_000646, SCHEMBL4358144, CTK4C5402, DTXSID70163696, MMCMKWDIEUZMQB-UHFFFAOYSA-N, HMS3262A13, Tox21_500646, BDBM50040245, 8-Methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido(2,3-b)(1,4)benzodiazepine, CCG-204733, LP00646, NCGC00015574-01, NCGC00015574-02, NCGC00015574-03, NCGC00015574-04, NCGC00094013-02, NCGC00261331-01, EU-0100646, J-102, SR-01000075386, SR-01000075386-1, 8-Methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido[2,3-b][1,4]benzeodiazepine, 8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine

ID: 1394

InChIKey: MMDQZMROSQWSDC-WBMJQRKESA-N
SMILES: C[C@]12CCC(=O)C[C@H]1CCC3=C2C=C(C=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708693
synonyms found at PubChem are:
Spectrum_000726, SpecPlus_000503, AC1O8FJV, Spectrum2_000266, Spectrum3_000057, Spectrum4_001339, Spectrum5_000217, BSPBio_001813, KBioGR_001837, KBioSS_001206, SPECTRUM100254, DivK1c_006599, SPBio_000112, SCHEMBL14478779, KBio1_001543, KBio2_001206, KBio2_003774, KBio2_006342, KBio3_000993, CCG-39941, NCGC00178986-01, BRD-K26376097-001-02-9, 5beta-12-METHOXY-4,4-BISNOR-8,11,13-PODOCARPATRIEN-3-ONE, (4aS,10aR)-6-methoxy-4a-methyl-1,3,4,9,10,10a-hexahydrophenanthren-2-one

ID: 1395

InChIKey: MMOXZBCLCQITDF-UHFFFAOYSA-N
SMILES: CCN(CC)C(=O)C1=CC(=CC=C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4284
synonyms found at PubChem are:
DEET, N,N-Diethyl-3-methylbenzamide, N,N-Diethyl-m-toluamide, 134-62-3, Diethyltoluamide, Dieltamid, Metadelphene, Flypel, Delphene, Detamide, Autan, m-Delphene, 3-Methyl-N,N-diethylbenzamide, DETA, Repudin-Special, Repel, Benzamide, N,N-diethyl-3-methyl-, M-Det, Diethyl toluamide, Naugatuck DET, m-DETA, m-Toluic acid diethylamide, Repper-DET, Diethyl-m-toluamide, Muscol, Repper DET, Amincene C-EM, Mgk diethyltoluamide, Dietiltoluamida, Amincene C 140, m-Toluamide, N,N-diethyl-, Diethyltoluamidum, DETA-20, DET (insect repellant), ENT 22542, Bepper DET, N,N-Diethyl-meta-toluamide, Caswell No. 346, ENT 20,218, N,N-diethyl-3-methyl-benzamide, UNII-FB0C1XZV4Y, NSC 33840, Diethyltoluamidum [INN-Latin], Dietiltoluamida [INN-Spanish], CCRIS 6018, HSDB 1582, AI 3-22542, EINECS 205-149-7, FB0C1XZV4Y, Off, EPA Pesticide Chemical Code 080301, BRN 2046711, CHEBI:7071, MMOXZBCLCQITDF-UHFFFAOYSA-N, 94271-03-1, NCGC00091219-02, Diethyltoluamide (DEET), N,N-Diethyl-meta-toluamide and other isomers, DSSTox_CID_1995, A.I. 3-22542, DSSTox_RID_76448, DSSTox_GSID_21995, Q-200984, CAS-134-62-3, SMR000777931, N,N-Diethyl-m-toluamide, analytical standard, metadelfene, Diethyltoluamide [USP:INN:BAN], Diethyltoluamide [USAN:INN:BAN], Off!, PubChem15448, Spectrum_001989, 3n7h, DIELTAMID(R), (N,N-diethyltoluamide), DELPHENE(R), DETAMIDE(R), m-Toluamide,N-diethyl-, n,n-diethyl m-toluamide, n-diethyl-meta-toluamide, FEYPEL(R), AC1L1HTH, META-DELPHENE(R), Spectrum2_001072, Spectrum4_000439, Spectrum5_002076, DEET, analytical standard, OFF(R), ACMC-1BV02, Diethyltoluamide (USP/INN), SCHEMBL29976, KBioGR_000798, KBioSS_002555, KSC174Q2D, MLS001333179, MLS001333180, MLS002207091, MLS002415750, DivK1c_000157, SPECTRUM1601020, SPBio_001084, Benzamide,N-diethyl-3-methyl-, N,N-DITHYL-M-TOLUAMIDE, ZINC1291, CHEMBL1453317, DTXSID2021995, N,N-DIETHYL-3-TOLUAMIDE, CTK0H4821, DEET 10 microg/mL in Methanol, HMS500H19, KBio1_000157, KBio2_002546, KBio2_005114, KBio2_007682, MolPort-002-317-244, NINDS_000157, WLN: 2N2 & VR C1, DEET 100 microg/mL in Methanol, HMS2094E11, HMS2231H11, HMS3372F07, N,N-Diethyl-m-toluamide, 98+%, Pharmakon1600-01601020, HY-B0978, KS-00000IS6, NSC33840, Tox21_111103, Tox21_201980, Tox21_300917, ANW-19692, LS-780, MFCD00009046, NSC-33840, NSC759564, s4521, AKOS003852835, N,N-Diethyl-3-methylbenzamide, 97%, Tox21_111103_1, AS01242, CCG-213639, CS-4468, N,N-diethyl(3-methylphenyl)carboxamide, NSC-759564, RP25106, RTR-004688, VZ36454, IDI1_000157, 3-METHYLBENZOIC ACID DIETHYLAMIDE, NCGC00091219-01, NCGC00091219-03, NCGC00091219-04, NCGC00091219-05, NCGC00091219-06, NCGC00091219-08, NCGC00254820-01, NCGC00259529-01, AC-11315, AJ-07999, AK-41340, AN-23088, AN-34940, BBV-34549990, CC-31796, CJ-00041, DEET, PESTANAL(R), analytical standard, DS-13831, KB-79121, SC-21727, ZB000304, ACM1215576014, SBI-0051886.P002, AX8018112, DB-042245, KB-183673, N,N-DIETHYL-M-METHYL PHENYLFORMAMIDE, TL8000811, TR-004688, D0097, FT-0629479, ST24031255, ST50406384, C10935, D02379, AB00052406_06, C-28155, SR-05000001887, I14-6109, SR-05000001887-1, BRD-K94080537-001-05-5, Z31723661, Diethyltoluamide, United States Pharmacopeia (USP) Reference Standard, DE3

ID: 1396

InChIKey: MMQONYKUNYFDEI-LLPMONEMSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C3[C@@]1(C45C(O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)(C(=O)CCC2(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708717
synonyms found at PubChem are:
KBio2_003788, Spectrum_000740, SpecPlus_000607, Spectrum2_000747, Spectrum3_000064, Spectrum4_001345, Spectrum5_000249, BSPBio_001847, KBioGR_001869, KBioSS_001220, SPECTRUM100290, 2,3-DIHYDROISOGEDUNIN, DivK1c_006703, SPBio_000734, SCHEMBL14196992, KBio1_001647, KBio2_001220, KBio2_006356, KBio3_001047, CCG-40155, SDCCGMLS-0066328.P001, NCGC00178959-01, SR-05000002719, SR-05000002719-1

ID: 1397

InChIKey: MNIPYSSQXLZQLJ-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 71771
synonyms found at PubChem are:
Aceclofenac, 89796-99-6, Preservex, Aceclofenaco, Aceclofenacum, Airtal, Falcol, Gerbin, Aceclofar, Aceclofenacum [Latin], Aceclofenaco [Spanish], Hifenac, Tresquim, Zerodol, UNII-RPK779R03H, CHEBI:31159, PR-82/3, BRN 4884476, C16H13Cl2NO4, RPK779R03H, Glycolic Acid [o-(2,6-Dichloroanilino)phenyl]acetate Ester, (2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetoxy)acetic acid, 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester, 2-(o-(2,6-Dichloranilino)phenylacetoxy)essigsaeure, 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid, NCGC00016957-01, 2-[2-[2-(2,6-dichloroanilino)phenyl]acetyl]oxyacetic acid, 2-((2,6-Dichlorophenyl)amino)benzeneacetic acid carboxymethyl ester, CAS-89796-99-6, DSSTox_CID_25522, DSSTox_RID_80928, DSSTox_GSID_45522, 2-((2,6-dichlorophenyl)amino)phenylacetoxyacetic acid, 2-[2-(2,6-Dichloroanilino)phenylacetoxy]acetic Acid, 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid, Bristaflam, 2-(2-(2-(2,6-dichlorophenylamino)phenyl)acetoxy)acetic acid, Biofenac, 2-(2-(2-((2,6-dichlorophenyl)amino)phenyl)acetoxy)acetic acid, Glycolic acid, (o-(2,6-dichloroanilino)phenyl)acetate (ester), 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester;, Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, carboxymethyl ester, SMR000718629, SR-01000802972, Aceclofenac [BAN:INN], Aceclofenac [INN:BAN], Barracan, Cincofen, [({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid, Clanza, [((2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL)ACETYL)OXY]ACETIC ACID, Aceclofenac betadex, Aceclofenac (TN), Prestwick_772, AC1Q3RRC, AC1Q3RRD, Aceclofenac (JAN/INN), Prestwick0_000175, Prestwick1_000175, Prestwick2_000175, Prestwick3_000175, ACMC-20b3n0, D0T8VY, AC1L2GS7, SCHEMBL25734, BSPBio_000069, MLS001032069, MLS001304028, MLS002154226, CHEMBL93645, SPBio_001990, BPBio1_000077, DTXSID7045522, Aceclofenac, >=98% (HPLC), CTK5G3502, MolPort-001-727-410, HMS1568D11, HMS2090G07, HMS2095D11, HMS2231B03, HMS3371A10, HMS3712D11, BCP11932, HY-B0634, ZINC3805798, Tox21_110710, BBL010788, BDBM50109016, BG0006, GP9829, MFCD00864296, STK594349, YT-919, AKOS005516194, Tox21_110710_1, AB07468, AC-5282, Aceclofenac 1.0 mg/ml in Acetonitrile, AN-3929, API0001355, CCG-213835, CS-2869, DB06736, KS-5033, MCULE-2034452601, NCGC00016957-02, NCGC00016957-03, NCGC00016957-05, AN-11172, LS-28738, SC-16690, AB0012517, TL8005786, FT-0621715, D01545, J10014, 796A996, I01-1305, SR-01000802972-2, SR-01000802972-3, BRD-K68538666-001-03-2, [2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid carboxymethyl ester, 2-[(2,6-Dichlorophenyl)-amino]benzeneacetic Acid Carboxymethyl Ester, 2-[2-[2-(2,6-DICHLOROPHENYL)AMINOPHENYL]ACETYL]OXYACETIC ACID, Aceclofenac for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 1398

InChIKey: MNLRQHMNZILYPY-PZYPBGQPSA-N
SMILES: C[C@H](C(=O)O)O[C@@H]1[C@@H](C(O[C@@H](C1NC(=O)C)O)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6713944
synonyms found at PubChem are:
Muramic acid, N-acetyl, Prestwick_718, AC1O8PWY, Prestwick0_000464, Prestwick1_000464, Prestwick2_000464, SPBio_002507, HMS1569M10, (2R)-2-[(2S,4S,5S)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoic acid

ID: 1399

InChIKey: MOLPUWBMSBJXER-YDGSQGCISA-N
SMILES: CC(C)(C)[C@@]1(C[C@H]2[C@@]3([C@]14[C@H](C(=O)O[C@H]4OC3=O)O)CC(=O)O2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 73581
synonyms found at PubChem are:
Bilobalide, 33570-04-6, Bilobalid, (-)-Bilobalide, UNII-M81D2O8H7U, CHEBI:3103, M81D2O8H7U, Bilobalide A, (3aS,8R,8aS,9R,10aS)-9-tert-butyl-8,9-dihydroxydihydro-9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 4H,5aH,9H-Furo(2,3-b)furo(3',2':2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (5aR-(3aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))-, tert-butyl(dihydroxy)[?]trione, C15H18O8, Bilobalide;, Bilobalide A;, (?)-Bilobalide, D0B0TK, AC1L2K4G, MLS000563448, SCHEMBL285824, GTPL2366, CHEMBL1318117, MolPort-004-955-258, HMS2205O12, BCP28255, HY-N0076, ZINC8679998, MFCD00132880, AKOS024282583, API0001715, CCG-208160, CS-1517, NCGC00142501-01, NCGC00142501-02, (-)-Bilobalide from Ginkgo biloba leaves, AJ-57900, AK160222, AS-17551, CC-24660, SMR000232342, ST057155, AX8007805, LS-183112, TR-031391, N1894, ST24046151, V0679, W-5094, 570B046, C-19867, SR-01000712074, Q-100409, SR-01000712074-4, (-)-Bilobalide from Ginkgo biloba leaves, >=93% (HPLC), (1S,4R,7R,8S,9R,11S)-9-tert-butyl-7,9-dihydroxy-3,5,12-trioxatetracyclo[6.6.0.0^{1,11}.0^{4,8}]tetradecane-2,6,13-trione, (1S,8S,12S,5R,14R)-14-(tert-butyl)-2,14-dihydroxy-4,6,11-trioxatetracyclo[6.6. 0.0<1,5>.0<8,12>]tetradecane-3,7,10-trione, 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (3aS,5aR,8R,8aS,9R,10aS)-, 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-,(3aS,5aR,8R,8aS,9R,10aS)-

ID: 1400

InChIKey: MOQZYUUHIWPDQC-UHFFFAOYSA-M
SMILES: CCCCCCC[N+](CC)(CC)CCCCC1=CC=C(C=C1)Cl.CC1=CC=C(C=C1)S(=O)(=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 175533
synonyms found at PubChem are:
Clofilium tosylate, 92953-10-1, UNII-13ZVF1051K, clofilium tosylateclofilium tosylate, N-(4-(4-Chlorophenyl)butyl)-N,N-diethylheptan-1-aminium 4-methylbenzenesulfonate, 13ZVF1051K, 4-Chloro-N,N-diethyl-N-heptylbenzenebutanaminium tosylate, NCGC00017142-01, CAS-92953-10-1, DSSTox_CID_25601, DSSTox_RID_80994, DSSTox_GSID_45601, Benzenebutanaminium, 4-chloro-N,N-diethyl-N-heptyl-, salt with 4-methylbenzenesulfonicacid (1:1), A1-01947, MLS002154263, 4-Chloro-N,N-Diethyl-N-Heptyl-Benzenebutanaminiusaltwith4-Methylbenzenes, GNF-Pf-3889, SMR001233522, Prestwick_682, ACMC-20ei9v, AC1L41KD, SCHEMBL467251, CHEMBL598270, DTXSID7045601, CTK8E7407, Clofilium tosylate, >97%, solid, HMS1568P20, HMS2095P20, HMS2234L09, HMS3374A08, HMS3712P20, BCP08356, CS-D0394, Tox21_110799, MFCD00069233, AKOS024257841, Tox21_110799_1, API0008443, CCG-220319, TRA0051317, NCGC00168464-04, AK325998, AS-30960, LS-29306, KB-125289, TX-017493, FT-0747981, C-54142, SR-01000838821, SR-01000838821-2, 4-(4-chlorophenyl)butyl-diethyl-heptylazanium; 4-methylbenzenesulfonate

ID: 1401

InChIKey: MOYKHGMNXAOIAT-JGWLITMVSA-N
SMILES: C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O[N+](=O)[O-])O[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6883
synonyms found at PubChem are:
ISOSORBIDE DINITRATE, 87-33-2, Sorbide nitrate, Sorbidnitrate, Isordil, Nitrosorbide, Isoket, Dinitrosorbide, Sorbidilat, Sorbitrate, Vascardin, Carvasin, Flindix, Isorbid, Isotrate, Sorbonit, Dilatrate-SR, Carvanil, Cedocard, Claodical, Cornilat, Corosorbide, Difutrat, Harrical, ISDN, Iso-Bid, Myorexon, Nitrosorbid, Nitrosorbon, Resoidan, Sorbangil, Sorbislo, Vasodilat, Vasorbate, Cardis, Coronex, Emoper, Korodil, Lomilan, Maycor, Rigedal, Sorquad, Tinidil, Nosim, Xanyl, Sorbide, dinitrate, Isordil Tembids, Rifloc Retard, Dilatrate, Cardio 10, Dianhydrosorbitol 2,5-dinitrate, Astridine, Isochron, Isodinit, Dinitroisosorbide, Isomak R, D-Isosorbide dinitrate, Cardonit 40, Dignionitrat, Sorbidinitrate, Corovliss, Disorlon, Langoran, Laserdil, Angidil, Diniket, Frandol, Isostat, Sorbide, Sorquat, Sorbidi nitras, EureCor, Isosorbide 2,5-dinitrate, IBD 20, BiDil, Dilatrate SR, Iso-Puren, Isosorbidi nitras, Iso-Mack, Isosorbidi dinitras, Sorate-5, Isoket retard 40, Sorbide T.D., Sorate-10, Isoket Retard 120, Dinitrate d'isosorbide, Dinitrato de isosorbida, Isosorbide dinitrato, Isosorbide dinitrato [DCIT], Isoket Retard-120, Titradose, D-Glucitol, 1,4:3,6-dianhydro-, dinitrate, Cedocard Retard, Isosorbidi dinitras [INN-Latin], SST-101, 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate, TYB 3215, Dinitrate d'isosorbide [INN-French], Isordil (TN), SDM No. 40, SDM No. 50, Dinitrato de isosorbida [INN-Spanish], Dilatrate-sr (TN), C6H8N2O8, CCRIS 1910, 1,4:3,6-Dianhydro-D-glucitol dinitrate, UNII-IA7306519N, HSDB 3417, EINECS 201-740-9, NSC 80038, UN2907, Isosorbide dinitrate [USAN:INN:BAN:JAN], CHEBI:6061, Glucitol, 1,4:3,6-dianhydro-, dinitrate, D-, NSC80038, D-Isosorbide dinitrate-Lactose mixture, IA7306519N, ISD, 1,4:3, 6-Dianhydro-D-glucitol dinitrate, 1,4:3,6-Dianhydrosorbitol 2, 5-dinitrate, (3R,3aS,6S,6aS)-6-(nitrooxy)-hexahydrofuro[3,2-b]furan-3-yl nitrate, [(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate, DSSTox_CID_25832, DSSTox_RID_81160, 1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol, DSSTox_GSID_45832, IsoBid, Iso Bid, Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid], SMR000857256, Isoket Retard120, Dinitrate, Isosorbide, SR-05000001658, D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate, (3R,3aS,6S,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl dinitrate, Isosorbidedinitrate, CAS-87-33-2, Sorbitrate (TN), Prestwick_81, NCGC00094703-01, Cedocard (TN), PubChem5889, r-isosorbide dinitrate, Glucitol, 1,4:3, Spectrum_000163, AC1L1NIG, Prestwick0_000714, Prestwick1_000714, Prestwick2_000714, Prestwick3_000714, Spectrum2_001069, Spectrum3_000600, Spectrum4_000025, Spectrum5_001057, Isosorbide Dinitrate,(S), D0I1SK, Diluted isosorbide dinitrate, EC 201-740-9, Isosorbide dinitrate [USAN:USP:INN:BAN:JAN], SCHEMBL8253, CHEMBL6622, BSPBio_000927, BSPBio_002080, KBioGR_000429, KBioSS_000643, MLS001333561, MLS001333562, ARONIS27194, DivK1c_000436, SPECTRUM1500358, SPBio_001058, SPBio_002848, BPBio1_001021, GTPL7051, DTXSID0045832, HMS501F18, KBio1_000436, KBio2_000643, KBio2_003211, KBio2_005779, KBio3_001580, NINDS_000436, HMS1570O09, HMS1920H15, HMS2091P05, HMS2097O09, HMS2230C09, HMS3714O09, Pharmakon1600-01500358, KS-000048OE, 1,6-Dianhydro-D-glucitol dinitrate, Tox21_111317, CCG-40110, NSC-80038, NSC757080, ZINC18089317, 1,6-Dianhydrosorbitol 2,5-dinitrate, AKOS015895227, AKOS015960761, AKOS015994784, Tox21_111317_1, API0003049, DB00883, GS-6631, Isosorbide dinitrate (JP15/USP/INN), Isosorbide dinitrate (JP17/USP/INN), NSC-757080, RP28223, IDI1_000436, KS-000026C5, NCGC00178830-01, NCGC00178830-02, NCGC00178830-05, AC-12153, AN-24118, CC-29721, D-Glucitol,4:3,6-dianhydro-, dinitrate, KB-52985, LS-71376, SBI-0051421.P003, AB00513900, FT-0603301, Glucitol,4:3,6-dianhydro-, dinitrate, D-, Z1918, C07456, D00516, AB00052026_07, C-13964, Glucitol, 1,4:3, 6-dianhydro-, dinitrate, D-, 3,6-Dianhydro-D-glucitol dinitrate ; Dilatrate-SR, SR-05000001658-1, SR-05000001658-3, SR-05000001658-5, W-104033, 1,4:3,6-dianhydro-2,5-di-O-nitro-D-erythro-hexitol, Z2433066075, (3S,3aS,6R,6aS)-6-(nitrooxy)-hexahydrofuro[3,2-b]furan-3-yl nitrate, [(3R,3aS,6S,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate, [(3S,3aS,6R,6aS)-6-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl] nitrate, 54650-95-2, 6659-58-1, Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate, Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]

ID: 1402

InChIKey: MOYOTUKECQMGHE-PDEFJWSRSA-M
SMILES: C[C@H]1CC[C@@H](O[C@H]1[C@@H](C)C(=O)[O-])C[C@@H]2C[C@H]([C@H]([C@@]3(O2)[C@@H](C[C@@](O3)(C)[C@H]4CC[C@@](O4)(C)[C@H]5[C@H](C[C@@H](O5)[C@@H]6[C@H](C[C@H]([C@@](O6)(CO)O)C)C)C)C)C)OC.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16219778
synonyms found at PubChem are:
Nigericin sodium, Nigericin sodium salt, Antibiotic K178, Nigericin (sodium salt), UNII-DGN38HI976, Sodium nigericin, DGN38HI976, 28643-80-3, NIGERICIN, MONOSODIUM SALT, NSC 292567, Nigericin, Sodium Salt, Streptomyces hygroscopicus, Helexin C, Antibiotic X464, SMR000875327, MLS001336037, MLS001336038, CHEMBL2165715, MolPort-003-938-748, AKOS024418750, AKOS032953798, CCG-208241, CS-5717, Nigericin sodium salt, >=98% (TLC), HY-100381, (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)- 2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-Hydroxy- 6-(hydroxymethyl)-3,5-dimethyl-2-tetrahydropyranyl]-3-methyl- 2-tetrahydrofuranyl]-5-methyl-2-tetrahydrofuranyl]-9-methoxy- 2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyl- 2-tetrahydropyranyl]propanoic acid sodium salt

ID: 1403

InChIKey: MOZPSIXKYJUTKI-UHFFFAOYSA-N
SMILES: CN1C=C(C2=CC=CC=C21)C(=O)OCC3CCN(CC3)CCNS(=O)(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 119376
synonyms found at PubChem are:
GR 113808, 144625-51-4, GR-113808, GR113808, UNII-ZT350OYT3I, ZT350OYT3I, CHEBI:73380, (1-(2-(Methylsulfonylamino)ethyl)-4-piperidinyl)methyl 1-methyl-1H-indole-3-carboxylate, GR-113,808, 1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulfonyl)amino)ethyl)-4-piperidinyl)methyl ester, (1-{2-[(methylsulfonyl)amino]ethyl}piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate, 1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate, 1-Methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester, 1-methyl-1H-indole-3-carboxylicacid,[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methylester, SR-01000075757, Tocris-1322, Lopac-G-5918, D08JLW, AC1L3OP5, Lopac0_000282, GTPL247, MLS000862181, CHEMBL33884, SCHEMBL1502039, BDBM29525, CTK8E9846, DTXSID40162772, MolPort-003-941-514, MOZPSIXKYJUTKI-UHFFFAOYSA-N, HMS2233H10, HMS3260J06, HMS3267N17, HMS3374F10, ZINC598220, Tox21_500282, BN0621, MFCD00912901, PDSP1_000842, PDSP1_001621, PDSP1_001699, PDSP2_000829, PDSP2_001605, PDSP2_001682, AKOS024456527, CCG-204377, LP00282, 3H-GR113808, NCGC00015477-01, NCGC00015477-02, NCGC00015477-03, NCGC00015477-04, NCGC00015477-05, NCGC00025110-01, NCGC00025110-02, NCGC00025110-03, NCGC00260967-01, [3H]GR113808, SMR000326944, [3H] GR 113808, LS-173222, RT-013114, B6688, EU-0100282, G 5918, GR 113808, >=98% (HPLC), solid, L000649, J-007977, SR-01000075757-1, SR-01000075757-3, BRD-K49945136-001-03-5, [1-(2-methanesulfonamidoethyl)piperidin-4-yl]methyl 1-methylindole-3-carboxylate, [1-[2-(methanesulfonamido)ethyl]piperidin-4-yl]methyl 1-methylindole-3-carboxylate

ID: 1404

InChIKey: MPDGHEJMBKOTSU-HDCNTZMNSA-N
SMILES: C[C@]12CC[C@@](C[C@H]1C3=CC(=O)C4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 44435791
synonyms found at PubChem are:
18 beta-glycyrrhetinic acid, CHEMBL393824

ID: 1405

InChIKey: MPHPHYZQRGLTBO-UHFFFAOYSA-N
SMILES: CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 26098
synonyms found at PubChem are:
Azapropazone, APAZONE, Cinnopropazone, Prolixan, Azapropazona, Azapropazonum, Cinnamin, Rheumox, Azapropazon, Mitrolan, Sinnamin, Prolix, Xani, 13539-59-8, Azapropazone (anhydrous), AHR-3018, Prolixan 300, MI 85, AHR 3018, Apazone [USAN], Azapropazon [German], Mi-85, NSC-102824, Azapropazone dihydrate, Azapropazonum [INN-Latin], Azapropazona [INN-Spanish], NSC 102824, 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, C16H20N4O2, 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine, EINECS 236-913-8, BRN 0623763, 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine, MLS002703748, CHEBI:38010, Apazone (USAN), Azapropazone (INN), Azapropazone [INN], NSC102824, 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione, Azapropazon (German), 1H-Pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, 5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione, SMR001233401, NCGC00016701-01, Prolixan (TN), CAS-13539-59-8, Tolyprin (Salt/Mix), AC1L1AEO, Prestwick0_001003, Prestwick1_001003, Prestwick2_001003, Prestwick3_001003, D01EQG, SCHEMBL3190, DSSTox_CID_23735, DSSTox_RID_80859, NCIOpen2_007171, DSSTox_GSID_45408, BSPBio_001125, MLS002154093, Apazone dihydrate (Salt/Mix), SPBio_003006, BPBio1_001239, CHEMBL1565476, DTXSID6045408, MPHPHYZQRGLTBO-UHFFFAOYSA-N, HMS1571I07, HMS2098I07, HMS2231L14, HMS3372M10, HMS3715I07, 22304-30-9 (di-hydrate), Tox21_110569, AKOS015914210, API0006579, CCG-221003, NCGC00179297-01, SC-43501, 1,2-(propylmalonyl)-1,2,4-benzotriazine, LS-128954, AB00513995, Y1648, D02966, SR-01000838825, SR-01000838825-2, I14-44468, WLN: T B566 BNV EVN HN DHJ D3 GN1&1 L1, 3-Dimethylamino-7-methyl-1,2-dihydro-1,2,4-benzotriazine, 3-Dimethylamino-7-methyl-1-2-(N-propylmalonyl)-1,2,4-benzotriazine, 1,2-Dihydro-3-(dimethylamino)-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine, 1H-Pyrazolo[1,2,4]benzotriazine-1,3(2H)-dione, 5-(dimethylamine)-9-methyl-2-propyl-, 1H-Pyrazolo[1,2,4]benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2,4]benzotriazine-1,3(2H)-dione, 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2,4]benzotriazine-1,3(2H)dione, 5-(dimethylamino)-9-methyl-2-propyl-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione, 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 5-(dimethylamine)-9-methyl-2-propyl-

ID: 1406

InChIKey: MPIPASJGOJYODL-UHFFFAOYSA-N
SMILES: C1=CC(=C(C(=C1)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3760
synonyms found at PubChem are:
Isoconazole, 27523-40-6, Isoconazolum, Isoconazol, Travogen, Isoconazol [INN-Spanish], Isoconazolum [INN-Latin], EINECS 248-508-3, CHEBI:83667, MPIPASJGOJYODL-UHFFFAOYSA-N, 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole, 1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole, 1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)1H-imidazole, DSSTox_CID_25447, DSSTox_RID_80886, DSSTox_GSID_45447, 1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)-1H-imidazole, 1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)-, 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-, Isoconazole [USAN:BAN:INN], Isoconazole [USAN:INN:BAN], NCGC00016800-01, Prestwick_532, CAS-27523-40-6, Miconazole Impurity D, AC1L1GNH, AC1Q3MZO, Prestwick0_000127, Prestwick1_000127, Prestwick2_000127, Prestwick3_000127, Isoconazole (USAN/INN), D0GJ7J, R15454, cid_3760, BSPBio_000174, MLS002154207, SCHEMBL148288, SPBio_002113, BPBio1_000192, CHEMBL1571863, DTXSID7045447, R-15454 [as nitrate salt], BDBM31771, 24168-96-5 (nitrate), HMS1568I16, HMS2095I16, HMS2231P05, HMS3374M05, HMS3712I16, 1-(2,4-dichloro beta-(2,6-dichlorobenzyloxy)phenethyl) imidazole, Tox21_110616, AKOS015896434, Tox21_110616_1, API0007221, CCG-220127, DB08943, 1-(2-(2,4-dichlorophenyl)-2-((2,6- dichlorophenyl)methoxy)ethyl)-1H-imidazole, NCGC00179642-01, NCGC00179642-03, NCGC00179642-04, NCGC00179642-05, R-15,454 [AS NITRATE SALT], LS-78388, SC-82853, SMR001233493, FT-0657773, D04624, A819101, SR-01000838847, I06-1865, SR-01000838847-2, BRD-A93353767-001-03-5, 1-(2-(2,6-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole, 1-[2,4-Dichloro-.beta.-[2,6-dichlorobenzyl)oxy]phenylethyl]imidazole, 1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole, 1-{2-[(2,6-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}imidazole, Imidazole, 1-(2,4-dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)-, 1-[2-[[2,6-bis(chloranyl)phenyl]methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole, Imidazole, 1-(2,4-dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)- (8CI)

ID: 1407

InChIKey: MPJUSISYVXABBH-UHFFFAOYSA-N
SMILES: CCC1(CCCCN(C1)C)C2=CC(=CC=C2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 65483
synonyms found at PubChem are:
MEPTAZINOL HYDROCHLORIDE, 59263-76-2, Meptazinol HCl, Meptazinol (hydrochloride), 3-(3-Ethylhexahydro-1-methyl-1H-azepin-3-yl)phenol hydrochloride, Meptazinol hydrochloride [USAN], EINECS 261-683-0, IL-22811 hydrochloride, WY-22811 hydrochloride, IL 22811, WY 22811, m-(3-Ethyl-1-methyl-hexahydro-1H-azepin-3-yl)phenol hydrochloride, m-(3-Ethylhexahydro-1-methyl-1H-azepin-3-yl)phenol hydrochloride, Phenol, 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-, hydrochloride, Phenol, m-(3-ethyl-1-methyl-hexahydro-1H-azepin-3-yl)-, hydrochloride, DSSTox_CID_25485, DSSTox_RID_80908, DSSTox_GSID_45485, 3-(3-ethyl-1-methylazepan-3-yl)phenol hydrochloride, 3-(3-ethyl-1-methyl-azepan-3-yl)phenol hydrochloride, Meptazinol hydrochloride (USAN), 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-phenol hydrochloride, 3-(3-ethyl-1-methylazepan-3-yl)phenol;hydrochloride, NCGC00016887-01, AC1L23BY, C15H23NO.HCl, CAS-59263-76-2, MLS002154094, SCHEMBL124401, IL 22811 HCl, IL-22811 HCl, WY 22811 HCl, CHEMBL1477274, DTXSID3045485, MolPort-003-848-496, MPJUSISYVXABBH-UHFFFAOYSA-N, WY-22811 HCL, HMS1571I09, 54340-58-8 (Parent), BCP12143, Tox21_110665, HY-17467A, MFCD00941476, s3204, AKOS015967029, Tox21_110665_1, AC-1652, AN-6771, API0000642, CCG-221004, CS-1813, QC-1539, NCGC00179295-03, AS-17434, BC220572, KB-53510, SMR001233402, 59263-76-2 (HCl), AB0019674, LS-104625, FT-0649313, V0121, D04924, 263M762, A832231, IL-22811 hydrochloride;WY-22811 hydrochloride, SR-01000838888, SR-01000838888-2, 3-(3-ethyl-1-methyl-3-azepanyl)phenol hydrochloride, 1-Methyl-3-ethyl-3-(m-hydroxy-phenyl)hexahydro-1H-azepine, AKOS026749824

ID: 1408

InChIKey: MPMFCABZENCRHV-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C2=O)C=C(C=C3)OCCN(CC)CC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5475
synonyms found at PubChem are:
tilorone, Bis-DEAE-fluorenone, 27591-97-5, Tilorone [INN], Tiloronum [INN-Latin], Tilorona [INN-Spanish], UNII-O6W7VEW6KS, Amixin IC, Tilorone hydrochloride, 2,7-Bis(2-(diethylamino)ethoxy)-9H-fluoren-9-one, C25H34N2O3, O6W7VEW6KS, BRN 2011558, DEAE-F, 9H-FLUOREN-9-ONE, 2,7-BIS(2-(DIETHYLAMINO)ETHOXY)-, 2,7-Bis-DEAE-fluorenone, RMI 10008DA, NCGC00095196-01, 2,7-bis(2-diethylaminoethyloxy)fluoren-9-one, DSSTox_CID_25958, DSSTox_RID_81254, DSSTox_GSID_45958, 2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one, Q-201835, 9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, Amiksin, Tilorona, Tiloronum, Amixin, Amyxin, CAS-27591-97-5, NSC143969, 2,7-Bis(2-diethylaminoethoxy)fluoren-9-one dihydrochloride, Spectrum_000231, AC1L1KFK, AC1Q6NBT, Spectrum2_001742, Spectrum3_001055, Spectrum5_001889, ChemDiv1_019101, Tiloron (*dihydrochloride*), Oprea1_331997, BSPBio_002610, KBioSS_000711, Tilorone hydrochloride(USAN), 2,7-bis[2-(diethylamino)ethoxy]-9h-fluoren-9-on, KSC559S4J, CHEMBL47298, DivK1c_000018, SCHEMBL352401, SPECTRUM2300009, SPBio_001844, DTXSID1045958, CTK4F9944, HMS500A20, HMS641E05, KBio1_000018, KBio2_000711, KBio2_003279, KBio2_005847, KBio3_001830, CHEBI:109553, MolPort-003-666-761, MPMFCABZENCRHV-UHFFFAOYSA-N, NINDS_000018, HMS1922J22, HMS2094I17, Pharmakon1600-02300009, ZINC538461, Tox21_111484, 27591-69-1 (di-hydrochloride), BDBM50364890, CCG-39449, NSC759311, RMI 10008DA (*dihydrochloride*), STL483841, AKOS025310183, Tox21_111484_1, MCULE-7636432960, NSC-759311, IDI1_000018, Bis-DEAE-fluorenone (*dihydrochloride*), NCGC00095196-02, NCGC00095196-03, NCGC00095196-06, NCGC00178576-01, AC-24571, AS-14877, KB-81160, LS-69311, M961, SBI-0052826.P002, TL8002218, FT-0718249, 2,7-Bis[2-(diethylamino)ethoxy]-9-fluorenone, A26270, AB00053319_02, 591T975, SR-05000001961, SR-05000001961-1, BRD-K34568562-001-03-5, BRD-K34568562-300-01-5, 2, {7-Bis[2-(diethylamino)ethoxy]fluoren-9-one} dihydrochloride, 2,7-bis(2-(diethylamino)ethoxy)-9h-fluoren-9-ondihydrochloride, 9H-Fluoren-9-one, {2,7-bis[2-(diethylamino)ethoxy]-,} dihydrochloride, Fluoren-9-one, 2, {7-bis[2-(diethylamino)ethoxy]-,} dihydrochloride

ID: 1409

InChIKey: MPXJSJVWSXWSNI-QWCSTTASSA-N
SMILES: CC(=O)C1=CC[C@@H]2[C@@]1(C(=O)C[C@H]3[C@H]2CCC4[C@@]3(CCC(C4)OC(=O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 25134274
synonyms found at PubChem are:
3-Acetoxypregn-16-en-12,20-dione, SCHEMBL2545903, acetic acid [(8R,9S,10S,13S,14S)-17-acetyl-12-keto-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,14,15-dodecahydrocyclopenta[a]phenanthren-3-yl] ester

ID: 1410

InChIKey: MQBNEMUIRRCVEU-UHFFFAOYSA-M
SMILES: CC(C)C(CO)[N+]1=CC2=CC=CC=C2C=C1.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10848382

ID: 1411

InChIKey: MQGPSCMMNJKMHQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281894
synonyms found at PubChem are:
7-Hydroxyflavone, 6665-86-7, Flavone, 7-hydroxy-, 7-Hydroxy-2-phenyl-4H-chromen-4-one, 7-Hydroxy-2-phenyl-4-benzopyrone, 4H-1-Benzopyran-4-one, 7-hydroxy-2-phenyl-, 7-hydroxy-2-phenylchromen-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-, NSC 94258, UNII-ZE72458E4L, 7-Hydroxy-2-phenyl-chromen-4-one, EINECS 229-705-3, NSC-94258, MLS002695239, CHEBI:2268, CHEMBL276915, MQGPSCMMNJKMHQ-UHFFFAOYSA-N, ZE72458E4L, NSC94258, 7-Hydroxy-2-phenyl-4H-1-benzopyran-4-one, H-5100, SR-01000359106, 7-Hydroxyflavone, 11, 7-Hydroxy-flavone, 5a, 7-Hydroxyflavone, 98%, ACMC-1BA9R, D01KKU, AC1NQZ90, Oprea1_774070, 7-Hydroxyflavone, >=98%, BIDD:ER0599, SCHEMBL312148, Flavone, 7-hydroxy- (8CI), MEGxp0_001698, DTXSID3022328, ACon1_000093, BDBM26664, MolPort-001-742-467, ZINC5934541, ZX-AT010702, ANW-75599, MFCD00006835, OR1155, SBB005921, AKOS000599907, CCG-208393, MCULE-9296935381, NCGC00163568-01, NCGC00163568-02, NCGC00168801-01, 7-Hydroxy-2-phenyl-4H-chromen-4-one #, AS-19983, CC-23209, KB-74174, SMR000112319, ST026594, SBI-0207061.P001, 7-hydroxy-2-phenyl-4-oxo-4H-1-benzopyran, 7-hydroxyflavone solution, 20 mM in DMSO, DB-054948, LS-195383, TR-022520, 4-Hydroxy-2-phenyl-7H-1-benzopyran-7-one, FT-0621434, Z3062, C11264, C-30816, SR-01000359106-1, SR-01000359106-3, 4H-1-Benzopyran-4-one, 7-hydroxy-2-phenyl- (9CI), 7-hydroxyflavone, disposable screening library format, BRD-K56450366-001-01-1, BRD-K56450366-001-03-7, I14-21791, 7-hydroxy-2-phenyl-4H-chromen-4-one solution, 20 mM in DMSO

ID: 1412

InChIKey: MQJKPEGWNLWLTK-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2955
synonyms found at PubChem are:
dapsone, 80-08-0, Diaphenylsulfone, 4,4'-Sulfonyldianiline, 4,4'-Diaminodiphenyl sulfone, Dapson, Diaphenylsulfon, Sulfona, 4-Aminophenyl sulfone, Avlosulfone, Diphenasone, Sulfadione, Disulone, Udolac, DADPS, Bis(4-aminophenyl) sulfone, 4,4'-Diaminodiphenylsulfone, Avlosulfon, Croysulfone, Dapsonum, Dumitone, Novophone, p-Aminophenyl sulfone, Sulphadione, Diphone, Eporal, Diaphenylsulphon, Diaphenylsulphone, Metabolite C, Sumicure S, Sulphonyldianiline, Sulfona-MAE, Avlosulphone, Croysulphone, Dubronax, Aczone, Diaminodiphenyl sulfone, Tarimyl, Bis(p-aminophenyl) sulfone, Sulfone ucb, Sulfonyldianiline, p,p-Sulphonylbisbenzamine, 4,4'-Dapsone, p,p-Sulphonylbisbenzenamine, Dapsona, p,p'-Diaminodiphenyl sulfone, Diaminodiphenylsulfone, 4,4'-Sulfonylbisaniline, Di(p-aminophenyl) sulfone, p,p-Sulphonyldianiline, 4,4'-Sulfonylbisbenzamine, Di(4-aminophenyl) sulfone, p,p'-sulfonyldianiline, p,p-Sulfonylbisbenzamine, Benzenamine, 4,4'-sulfonylbis-, Diaminodifenilsulfona, DDS, pharmaceutical, Di(p-aminophenyl)sulphone, Sulfanona-mae, p,p-Sulfonylbisbenzenamine, Araldite HT 976, Bis(p-aminophenyl)sulphone, Di(4-aminophenyl)sulphone, Sulfon-mere, Bis(4-aminophenyl)sulphone, p,p-Diaminodiphenyl sulphone, N,N'-Diphenyl sulfondiamide, 4,4'-Sulfonylbisbenzenamine, 4,4'-Sulphonyldianiline, Di(4-aminophenyl)sulfone, NSC-6091, Bis(4-aminophenyl)sulfone, Hardener HT 976, 4-(4-aminophenyl)sulfonylaniline, 4,4'-Sulphonylbisbenzamine, DDS (pharmaceutical), Sulphon-mere, 4,4'-Sulphonylbisbenzenamine, 1,1'-Sulfonylbis(4-aminobenzene), Araldite HT, Dapsonum [INN-Latin], Dapsona [INN-Spanish], 4,4'-Diaminodiphenyl sulphone, WR 448, 4,4-Diaminodifenylsulfon, Diamino-4,4'-diphenyl sulfone, Diamino-4,4'-diphenyl sulphone, NSC 6091D, DSS (VAN), NCI-C01718, 1,1'-Sulfonylbis[4-aminobenzene], DDS, 1,1'-Sulphonylbis(4-aminobenzene), DDS, diaphenylsulfone, Aniline, 4,4'-sulfonyldi-, 4,4'-Diaminodiphenyl suphone, HT 976, Atrisone, Avsulfor, Diaminodifenilsulfona [Spanish], Dimitone, Dubronaz, Protogen, Dapsone [USAN:BAN], 4,4'-diamino diphenyl sulphone, F 1358, 4,4-Diaminodifenylsulfon [Czech], 4,4'-Sulfonyldianiline (Dapsone), 1358F, 4,4'-diaminophenyl sulfone, 4-[(4-aminobenzene)sulfonyl]aniline, HY 976, 4,4'-Sulfonylbisbenzeneamine, CCRIS 192, Dapsone (USP), 4-Aminophenylsulfone, Aczone (TN), 4,4-Sulfonyldianiline, HSDB 5073, 4,4'-Sulfonyldianilin, 4-Aminop henyl sulfone, Diaphenylsulfone (JAN), UNII-8W5C518302, p, p'-Sulfonyldianiline, Diamino-diphenyl sulphone, NSC 6091, D SS, Sulfone, diphenyl, 4,4'-diamino-, EINECS 201-248-4, (4-sulfanilylphenyl)amine, AZT + Dapsone cominbation, BRN 0788055, CHEMBL1043, N, N'-Diphenyl sulfondiamide, AI3-08087, MLS000069409, CHEBI:4325, NSC6091, 4-(4-aminobenzenesulfonyl)aniline, MQJKPEGWNLWLTK-UHFFFAOYSA-N, 4,4'-DDS, 4-[(4-aminophenyl)sulfonyl]aniline, ALBB-005917, IN-201, W R 448, 4-[(4-Aminophenyl)sulfonyl]phenylamine, NCGC00016322-08, SMR000059064, DSSTox_CID_371, 8W5C518302, DSSTox_RID_75547, DSSTox_GSID_20371, Dapson-Fatol, Dapsoderm-X, CAS-80-08-0, SR-01000002976, 4,4' Diaminophenyl Sulfone, Servidapson, Slphadione, Sulfone, 4,4'-Diaminophenyl, diaphenylsulfone;, Diaphenyl sulfone, Dapsone [USAN:USP:INN:BAN], Dapsone-d8, Dapsone,(S), Prestwick_152, BIS SULFONE, 4,4''-dapsone, Fatol Brand of Dapsone, Spectrum_000888, ACMC-209piw, Orsade Brand of Dapsone, Aniline,4'-sulfonyldi-, AC1L1EUH, Opera_ID_1950, Prestwick0_000035, Prestwick1_000035, Prestwick2_000035, Prestwick3_000035, Spectrum2_001133, Spectrum3_000375, Spectrum4_000310, Spectrum5_000825, WLN: ZR DSWR DZ, 4,4''-sulfonyldianiline, N'-Diphenyl sulfondiamide, 4,4''-sulfonylbisaniline, 4'-Diaminodiphenyl sulfone, 4,4-Diaminodiphenylsulfone, D0MA9N, EC 201-248-4, 4,4'-Sulfonyldiphenylamine, AC1Q51WM, AC1Q51WN, Benzenamine,4'-sulfonylbis-, 4,4-Diaminodiphenyl Sulfone, Oprea1_143052, SCHEMBL21428, BSPBio_000129, BSPBio_002129, CBDivE_013582, Dianiline, 4,4'-sulfonyl-, KBioGR_000900, KBioSS_001368, KSC647I3R, Mex-America Brand of Dapsone, MLS001055349, MLS001076146, 4,4''-Sulfonylbisbenzenamine, 4,4'-Sulfonylbis-benzenamine, 4,4'-Sulfonylbis[benzamine], 4-Aminophenyl sulfone, 97%, BIDD:GT0770, DivK1c_000573, p,p''-diaminodiphenyl sulfone, SPECTRUM1500222, SPBio_001025, SPBio_002050, 4,4''-diaminodiphenyl sulfone, BPBio1_000143, ZINC6310, DTXSID4020371, CTK5E7438, HMS501M15, KBio1_000573, KBio2_001368, KBio2_003936, KBio2_006504, KBio3_001349, MolPort-001-780-172, NINDS_000573, HMS1568G11, HMS1920C14, HMS2091K04, HMS2095G11, HMS2231G09, HMS3259C13, HMS3369B11, HMS3712G11, Pharmakon1600-01500222, ACT07431, EBD28910, HY-B0688, KS-00000JP1, 1,1''-sulfonylbis(4-aminobenzene), Tox21_110371, Tox21_201347, Tox21_300558, ANW-37350, BBL002412, BDBM50029764, CCG-40260, CD0112, MFCD00007887, NSC756716, s4612, SBB003168, STK387118, AKOS000119322, Tox21_110371_1, CS-2928, DB00250, HT 9664, KS-1450, LS-1790, LS10738, MCULE-7294380437, NC00488, NSC-756716, RP28805, RTR-025382, IDI1_000573, 4-(4-amino-benzenesulfonyl)-phenylamine, NCGC00016322-01, NCGC00016322-02, NCGC00016322-03, NCGC00016322-04, NCGC00016322-05, NCGC00016322-06, NCGC00016322-07, NCGC00016322-09, NCGC00016322-10, NCGC00016322-13, NCGC00023946-03, NCGC00023946-04, NCGC00023946-05, NCGC00023946-06, NCGC00254533-01, NCGC00258899-01, AC-10922, AN-24011, CJ-00109, CPD000059064, SAM002554879, SC-46793, ZB000637, 4-[(4-Aminophenyl)sulfonyl]phenylamine #, SBI-0051331.P003, AB1004833, KB-105651, TL8005401, AB00051962, D0089, Dapsone, VETRANAL(TM), analytical standard, FT-0624447, R1186, ST50308134, 4 inverted exclamation marka-Sulfonyldianiline, C07666, D00592, AB00051962_19, A839828, 4 inverted exclamation marka-Diaminodiphenyl sulfone, I01-3640, Q-200435, SR-01000002976-2, SR-01000002976-4, BRD-K62363391-001-05-8, BRD-K62363391-001-15-7, 4 4-Diamino Diphenyl Sulfone 99.5%min Cas:80-08-8, Dapsone, European Pharmacopoeia (EP) Reference Standard, F0266-3067, Dapsone, United States Pharmacopeia (USP) Reference Standard, Dapsone, Pharmaceutical Secondary Standard; Certified Reference Material, 1246638-15-2, 4,4 inverted exclamation marka-Diaminodiphenyl sulfone; 4,4 inverted exclamation marka-Sulfonyldianiline; Bis(4-aminophenyl) sulfone; Dapsone

ID: 1413

InChIKey: MQNYRKWJSMQECI-QFIPXVFZSA-N
SMILES: CC[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6604009
synonyms found at PubChem are:
SB 222200, 174635-69-9, SB-222200, 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide, SB222200, CHEMBL10284, MQNYRKWJSMQECI-QFIPXVFZSA-N, (S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide, 4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-, S 5192, C26H24N2O, (S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide, 3-METHYL-2-PHENYL-N-[(1S)-1-PHENYLPROPYL]-4-QUINOLINECARBOXAMIDE, SMR000326963, 4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-((1S)-1-phenylpropyl)-, Tocris-1393, Lopac-S-5192, D00VPT, Lopac0_000100, MLS000862200, MLS001056793, AC1O7G71, GTPL2131, SCHEMBL3105312, CHEBI:92079, CTK8E7295, MolPort-021-805-005, BCPP000078, HMS2232O13, HMS3260C22, HMS3267F04, BCP02659, N-(alpha-ethylbenzyl)-3-methyl-2-phenylquinoline-4-carboxamide, ZINC1543563, Tox21_500100, 4025AH, ABP000799, BDBM50051295, MFCD00944072, AKOS024456569, API0007580, CCG-204195, CS-1647, LP00100, NCGC00015956-01, NCGC00015956-02, NCGC00015956-03, NCGC00015956-04, NCGC00015956-05, NCGC00015956-06, NCGC00025140-01, NCGC00025140-02, NCGC00025140-03, NCGC00025140-04, NCGC00260785-01, CJ-05288, HY-15722, KB-268715, RT-015644, EU-0100100, SB 222200, >=98% (HPLC), solid, SR-01000075703, SR-01000597583, A1-01875, J-011023, SR-01000075703-1, SR-01000597583-1, BRD-K04414442-001-03-4, 3-Methyl-2-phenyl-N-[(1S)-1-phenylp ropyl]-4-quinolinecarboxamide, 3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide, 4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-(1-phenylpropyl)-, (S)-

ID: 1414

InChIKey: MQPMUBUNWXDTIX-UHFFFAOYSA-M
SMILES: CC(C)C(CO)[N+]1=CC=C(C=C1)C2=CC=CC=C2.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10850178

ID: 1415

InChIKey: MQTOSJVFKKJCRP-BICOPXKESA-N
SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 447043
synonyms found at PubChem are:
azithromycin, Zithromax, 83905-01-5, Azithromycine, Azithromycinum, Sumamed, Zitromax, Zmax, Azitrocin, Hemomycin, Azasite, Azenil, Aritromicina, Mixoterin, Zithrax, Zitrotek, Aziwok, Aztrin, Setron, Zitrim, Tobil, Zifin, Zeto, Zmas, Azithromycine [French], Azithromycinum [Latin], AZITHROMYCIN DIHYDRATE, Zithromax IV, Azitromax, Misultina, Tromix, Z-Pak, CP-62993, Aritromicina [Spanish], Azitromicina, UNII-J2KLZ20U1M, DRG-0104, Azithromycin Monohydrate, CCRIS 1961, HSDB 7205, Azithromycin (anhydrous), C38H72N2O12, BRN 5387583, J2KLZ20U1M, Azythromycin, CHEBI:2955, Azithromycin (AIDS Initiative), MQTOSJVFKKJCRP-BICOPXKESA-N, 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A, CP 62993, Azithromycin [USAN:INN:BAN], 117772-70-0, NCGC00090753-01, XZ-450, DSSTox_CID_10760, DSSTox_RID_78858, DSSTox_GSID_30760, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one, 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, (2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*))-, Azitromicine, Trulimax, Zentavion, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, SMR000471864, ZIT, Azithromycin (Zithromax), CAS-83905-01-5, Azithromycin hydrate, Z-Pak (Azithromycin), SR-05000002067, Azithromycin, Antibiotic for Culture Media Use Only, arzomicin, aziromycin, Zithromycin, Azifast, Azigram, Azimakrol, Azitromin, Zithromac, Azyter, Aycin, Azithromycin A, NSC643732, Azithromycin,(S), Zmax SR, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside, azithromycin anhydrous, Zitromax Avium 600, Azitromicina [Spanish], Spectrum_000307, 9-Deoxy-9a-aza-9a-methyl-9a-homoerythromycin A, AC1L9KEG, DCH3, Spectrum2_001582, Spectrum3_000653, Spectrum4_000186, Spectrum5_001867, AZM, CHEMBL529, D03HJK, EC 617-500-5, Zithromax, Azithrocin, Azin, SCHEMBL23481, BSPBio_002285, KBioGR_000731, KBioSS_000787, MLS001055353, MLS001066331, MLS001201763, MLS001304005, MLS001332499, MLS001332500, BIDD:GT0792, DivK1c_000233, SPECTRUM1503679, SPBio_001544, GTPL6510, CHEMBL3736045, DTXSID8030760, Azithromycin, analytical standard, HMS500L15, KBio1_000233, KBio2_000787, KBio2_003355, KBio2_005923, KBio3_001505, SYN3010, MolPort-002-507-426, NINDS_000233, HMS1922G12, HMS2094M11, HMS2232M10, HMS3259D10, 117772-70-0 (dihydrate), 121470-24-4 (monohydrate), ACT03224, Tox21_111008, Tox21_201011, BDBM50373918, CCG-39360, ZINC85537026, AKOS015895044, CS-2308, DB00207, EBD2198275, LS-1834, MCULE-8817893418, NC00712, IDI1_000233, NCGC00090753-02, NCGC00090753-03, NCGC00090753-04, NCGC00258564-01, AC-16014, BC204085, CP62,993, CPD000471864, HY-17506, SAM002589961, SBI-0206706.P001, CP-62993-3, 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-, A-9940, A-9941, 24238-EP2295402A2, 24238-EP2314590A1, 24238-EP2380874A2, AB00698251-10, AB00698251_11, 905A015, SR-05000002067-1, SR-05000002067-2, BRD-K74501079-001-18-1, Z1563146014, UNII-F94OW58Y8V component MQTOSJVFKKJCRP-BICOPXKESA-N, Azithromycin, European Pharmacopoeia (EP) Reference Standard, Azithromycin Identity, United States Pharmacopeia (USP) Reference Standard, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-((2S,3R,4S,6R)-, Azithromycin for peak identification, European Pharmacopoeia (EP) Reference Standard, Azithromycin for system suitability, European Pharmacopoeia (EP) Reference Standard, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-, 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*, 104491-80-7, 142556-82-9

ID: 1416

InChIKey: MQUQNUAYKLCRME-INIZCTEOSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)CCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 439647
synonyms found at PubChem are:
TPCK, 402-71-1, Tos-Phe-CH2Cl, TOSYLPHENYLALANYL CHLOROMETHYL KETONE, N-Tosyl-L-phenylalanine chloromethyl ketone, N-Tosyl-L-phenylalanyl chloromethyl ketone, N-p-Tosyl-L-phenylalanine chloromethyl ketone, Tos-Phe-chloromethylketone, L-1-Tosylamido-2-phenylethyl chloromethyl ketone, l-N-(alpha-(Chloroacetyl)phenethyl)-p-toluenesulfonamide, CHEMBL60718, UNII-P598716LJT, MLS000028752, CHEBI:9642, MQUQNUAYKLCRME-INIZCTEOSA-N, P598716LJT, N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide, SMR000058518, p-Toluenesulfonamide, N-(alpha-(chloroacetyl)phenethyl)-, (-)-, (S)-N-(4-Chloro-3-oxo-1-phenylbutan-2-yl)-4-methylbenzenesulfonamide, Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)-, Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-, L-1-p-Tosylamino-2-phenylethyl chloromethyl ketone, EINECS 206-954-6, BRN 2895215, Tosyl-L-phenylalanyl-chloromethane, L-Chloromethyl (2-phenyl-1-(p-toluenesulphonylamino)ethyl) ketone, Benzenesulfonamide, N-[3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-, (S)-, Tosylphenylalanyl chloromethyl ketone, (L)-, Opera_ID_1094, Lopac-T-4376, tosylphenylalanylchloromethane, Lopac0_001157, BSPBio_001541, KBioGR_000261, KBioSS_000261, MLS001076075, MLS006010721, SCHEMBL927265, AC1L97R8, cid_439647, Tosyl-L-phenylalanylchloromethane, KBio2_000261, KBio2_002829, KBio2_005397, KBio3_000521, KBio3_000522, KS-00000XQS, BRD5988, MolPort-028-959-653, Bio2_000261, Bio2_000741, HMS1361N03, HMS1791N03, HMS1989N03, HMS3263H15, HMS3402N03, ZINC901254, BRD-5988, Tox21_501157, 7793AH, ACM329306, BDBM50085363, NSC727365, PI-122, AKOS027327594, CCG-205231, LP01157, NSC-727365, IDI1_034011, NCGC00016020-01, NCGC00094419-01, NCGC00094419-02, NCGC00094419-03, NCGC00094419-04, NCGC00094419-05, NCGC00094419-06, NCGC00261842-01, AS-35326, KB-75264, p-Tosyl-L-phenylalanine chloromethylketone, EU-0101157, FT-0627626, N-P-tosyl-L-phenylalanyl chloromethyl ketone, C02088, K-8605, L-1-Tosylamido-2-phenylethylchloromethyl ketone, T 4376, (S)-1-Chloro-3-tosylamido-4-phenyl-2-butanone, (S)-1-Chloro-4-phenyl-3-tosylamido-2-butanone, SR-01000076157, SR-01000076157-1, BRD-K07055988-001-02-4, N-(p-Toluenesulfonyl)-L-phenylalanine chloromethyl ketone, l-N-(.alpha.-(Chloroacetyl)phenethyl)-p-toluenesulfonamide, (3S)-3-(p-Toluenesulfonyl)amino-1-chloro-4-phenyl-2-butanone, (S)-N-(4-Chloro-3-oxo-1-phenyl-2-butyl)-p-toluenesulfonamide, L-([Toluene-4-sulfonamido]-2-phenyl)ethyl chloromethyl ketone, p-Toluenesulfonamide, N-(.alpha.-(chloroacetyl)phenethyl)-, (-)-, N-[(1S)-1-benzyl-3-chloro-2-oxo-propyl]-4-methyl-benzenesulfonamide, N-p-Tosyl-L-phenylalanine chloromethyl ketone, >=97% (TLC), powder, 130021-38-4

ID: 1417

InChIKey: MQZIGYBFDRPAKN-UWFIBFSHSA-N
SMILES: CC1=C(C(C[C@@H](C1=O)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)/C)/C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5281224
synonyms found at PubChem are:
Astaxanthin, 472-61-7, Ovoester, Astaxanthine, all-trans-Astaxanthin, Natupink, BioAstin, Carophyll Pink, Lucantin Pink, (3S,3'S)-Astaxanthin, trans-Astaxanthin, UNII-8XPW32PR7I, AstaREAL, BioAstin oleoresin, Astaxanthin, (3S,3'S)-, Astaxanthin (6CI), 3S,3'S-Astaxanthin, (3S,3'S)-all-trans-Astaxanthin, Astaxanthin, all-trans-, 8XPW32PR7I, CHEBI:40968, MQZIGYBFDRPAKN-UWFIBFSHSA-N, 3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, CCRIS 7118, HSDB 7468, EINECS 207-451-4, NSC 635689, Astaxanthin, all-trans-, (3S,3'S)-, 3,3'-Dihydroxy-beta-carotene-4,4'-dione, (3R,3'S)-Astaxanthin, (3'RS,3'SR)-Astaxanthin, (3S,3'S)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, astaxantin, 3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, (3S,3'S)-, Aquasta, Astared, AstaXin, beta,beta-Carotene-4,4'-dione, 3,3'-dihydroxy-, (3S,3'S)-, NatuRose, Astots 5O, AXT, (S,S)-Astaxanthin, Astots 10O, Astaxanthin, 5% active, AC1NQY7R, Coriolus Versicolor Extract, SCHEMBL20047, E161j, CHEMBL1255871, Astaxanthin, >=98% (HPLC), E 161j, all-trans-(3S,3'S)-astaxanthin, MolPort-006-069-279, MolPort-044-723-450, BCP05821, .beta.,.beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, (3S,3'S)-, CA0143, LMPR01070263, AKOS015841055, AKOS015895756, ZINC100042059, AC-8760, BCP9000329, DB06543, 3,3'-dihydroxy-?-carotene-4,4'-dione, 3,3'-dihydroxy-ss-carotene-4,4'-dione, all-trans-Astaxanthin, analytical standard, AS-14095, BC678546, SC-15878, FT-0081075, C08580, M01303, 3,3'-dihydroxy-4,4'-diketo-beta,beta-carotene, 472A617, I06-1497, Q-200655, all-trans-3,3'-dihydroxy-b-Carotene-4,4'-dione (8CI), (3R,3'S)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans-, all-trans-3,3'-dihydroxy-beta-Carotene-4,4'-dione (8CI), UNII-E9AI950EAH component MQZIGYBFDRPAKN-UWFIBFSHSA-N, 3,3'-Dihydroxy-.beta.,.beta.-carotene-4,4'-dione, (3S,3'S)-, (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1, (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one, (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-en-1-one), (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone)

ID: 1418

InChIKey: MRAUNPAHJZDYCK-BYPYZUCNSA-N
SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 440005
synonyms found at PubChem are:
H-Arg(NO2)-OH, 2149-70-4, NG-Nitro-L-arginine, L-NNA, NITROARGININE, N-Nitro-L-arginine, Nomega-Nitro-L-arginine, N(G)-Nitro-L-arginine, NG-NO2-L-Arg, (S)-2-Amino-5-(3-nitroguanidino)pentanoic acid, N-OMEGA-NITRO-L-ARGININE, N(G)-Nitroarginine, Nitro-L-arginine, NG-nitroarginine, L-Nw-nitroarginine, Ngamma-Nitro-L-arginine, NSC 53662, UNII-7O8V7H6P2J, 7O8V7H6P2J, CHEMBL227744, N (g)-NITRO-L-ARGININE, l-na, MRAUNPAHJZDYCK-BYPYZUCNSA-N, L-nitroarginine, ZINC19796052, Ornithine, N(5)-(nitroamidino)-, L-, L-NG-nitroarginine, Norvaline, 5-(2-nitroguanidino)-, (+)-, NRG, omega-Nitroarginine, .omega.-Nitroarginine, Arginine, omega-nitro-, N(G)-Methyl-L-arginine, N omega-Nitro-L-Arginine, Arginine, .omega.-nitro-, N(sup G)-Nitro-L-arginine, Arginine, omega-nitro-, L-, EINECS 218-418-9, L-N-Nitroarginine, arg(no2), AI3-62168, NOLA, N?-Nitro-L-arginine, hDDAH inhibitor, 2g, NG -nitro-L-arginine, L-NOARG, N|O-Nitro-L-arginine, PubChem18967, Tocris-0664, (+)-NG-Nitroarginine, H-Arg(NO2), Spectrum2_001478, Spectrum3_001083, Spectrum4_001236, Spectrum5_001019, L-NOARG; L-NNA, .omega.-Nitro-L-arginine, D0G2UL, [N(g)-nitro-L-arginine], N(omega)-Nitro-L-arginine, N.omega.-Nitro-L-arginine, AC1L98HL, Lopac0_000818, BSPBio_002726, KBioGR_001732, L-Arginine, .omega.-nitro-, DivK1c_001016, DivK1c_001033, SCHEMBL345312, SPECTRUM1502155, SPBio_001435, GTPL8759, N5-(nitroamidino)-L-Ornithine, Arginine, .omega.-nitro-, L-, DTXSID2042696, SCHEMBL14220319, BDBM21958, CHEBI:27960, HMS503K13, HMS503O07, KBio1_001016, KBio1_001033, KBio3_001946, MolPort-003-666-415, NINDS_001016, NINDS_001033, Arginine, N(G)-nitro-, (L)-, BDBM235692, HMS1921L10, HMS3262D17, Arginine, N(G)-nitro-, (+)-, ALBB-015801, BCP19702, KS-00000K8T, Tox21_500818, BDBM50225106, CCG-39196, HSCI1_000287, MFCD00007033, STL466167, compound 2 [PMID: 9667974], AKOS005175145, DB04223, LP00818, MCULE-6760819058, N5-(N-nitrocarbamimidoyl)-L-ornithine, IDI1_001016, IDI1_001033, NCGC00024716-01, NCGC00024716-02, NCGC00024716-03, NCGC00024716-04, NCGC00024716-05, NCGC00261503-01, DS-13295, N~5~-(N-nitrocarbamimidoyl)-L-ornithine, NG-nitro-L-Arginine, L-NG-Nitroarginine, SC-09342, AB0032483, TC-164423, EU-0100818, FT-0629730, N~5~-[imino(nitroamino)methyl]-L-ornithine, N0660, ST24032103, X5791, C03417, L-ornithine, N~5~-[imino(nitroamino)methyl]-, M-8585, M03121, N 5501, N-2570, 14000-EP2305257A1, 14000-EP2316836A1, 2-Amino-5-(N''-nitro-guanidino)-pentanoic acid, SR-01000597670, J-300041, SR-01000597670-1, (S)-2-Amino-5-(N''-nitro-guanidino)-pentanoic acid, (2S)-2-amino-5-(3-nitrocarbamimidamido)pentanoic acid, (2S)-2-amino-5-{[imino(nitroamino)methyl]amino}pentanoic acid, (2S)-2-amino-5-[[amino(nitramido)methylene]amino]pentanoic acid, (2S)-2-amino-5-[[amino(nitramido)methylidene]amino]pentanoic acid, (2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino}pentanoic acid, (2S)-2-amino-5-{[(E)-imino(nitroamino)methyl]amino}pentanoic acid, (2S)-2-amino-5-[(E)-[amino(nitroamino)methylidene]amino]pentanoic acid, (2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino}pentanoic acid]], 2-[{[(4S)-4-amino-4-carboxybutyl]amino}(imino)methyl]-1-oxo-1-hydraziniumolate, 126265-23-4, 13855-78-2, 38733-00-5

ID: 1419

InChIKey: MRIAQLRQZPPODS-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 72344
synonyms found at PubChem are:
Nobiletin, 478-01-3, Hexamethoxyflavone, 5,6,7,8,3',4'-Hexamethoxyflavone, UNII-D65ILJ7WLY, C21H22O8, 3',4',5,6,7,8-Hexamethoxyflavone, CCRIS 9012, 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one, NSC 76751, NSC-76751, D65ILJ7WLY, CHEMBL76447, Nobiletin (Hexamethoxyflavone), CHEBI:7602, MRIAQLRQZPPODS-UHFFFAOYSA-N, NSC76751, CPD000156231, Flavone, 5,6,7,8,3',4'-hexamethoxy, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromen-4-one, 4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-, SMR000156231, Nobiletin, >=97%, AC1Q6AJA, Spectrum2_001697, Spectrum3_000921, Spectrum4_001020, AC1L2HW1, KBioGR_001519, MLS000574877, MLS000759462, MLS000877030, MLS001424129, Nobiletin, analytical standard, SCHEMBL244029, SPECTRUM1505268, SPBio_001654, MEGxp0_000930, ACon1_000921, CTK4J0325, KBio3_001922, DTXSID30197275, MolPort-001-741-083, HMS2051D09, HMS2234A09, HMS3373C14, HMS3393D09, HMS3651G20, HY-N0155, ZINC1531669, 3,4,5,6,7,8-Hexamethoxyflavone, ANW-42631, BDBM50338976, CCG-38781, CN0043, LMPK12111468, MFCD03273560, NSC618903, AKOS015965334, NOBILETIN, 20% (Technical Grade), AC-1023, API0003613, CS-5518, MCULE-1015144950, NC00186, NSC-618903, RTR-031721, SDCCGMLS-0066776.P001, NCGC00095703-01, NCGC00095703-02, NCGC00169228-01, 5,6,7,8,3'',4''-hexamethoxyflavone, AN-15321, AS-17452, BC216281, LS-39643, NCI60_041691, SAM001246662, SC-25982, TR-031721, FT-0686667, N0871, N1311, S2333, V0181, C10112, SR-01000712262, Q-100511, SR-01000712262-5, BRD-K06753942-001-02-0, I14-100643, 2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chromen-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one, 4H-1-Benzopyran-4-one,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H- 1-benzopyran-4-one, 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one, 9CI, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy- (9CI)

ID: 1420

InChIKey: MSIJLVMSKDXAQN-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 62413
synonyms found at PubChem are:
CHLORCYCLIZINE HYDROCHLORIDE, CHLORCYCLIZINE HCl, Histantin, Eramide, Perazil, 1620-21-9, Di-Paralene, Chlorcyclizinium chloride, 14362-31-3, Chlorcyclizine chloride, Chlorcyclizine monohydrochloride, EINECS 238-335-1, NSC 169496, Chlorcyclizine (hydrochloride), 1-(p-Chlorobenzhydryl)-4-methylpiperazine monohydrochloride, 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine monohydrochloride, Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, monohydrochloride, (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine), Di-Paralene monohydrochloride, SMR001233306, Chlorcylizine, chlorcyclizinehcl, 1-((4-Chlorophenyl)(phenyl)methyl)-4-methylpiperazine hydrochloride, 1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine hydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine;hydrochloride, SR-05000001920, Chlorcyclizine hydrochloride [USP], Prestwick_967, component of Fedrazil, Ah-289 hydrochloride, Diparalene hydrochloride, NCGC00016589-01, CAS-1620-21-9, AC1L1X2Q, Chlorocyclizine hydrochloride, DSSTox_CID_25360, DSSTox_RID_80825, DSSTox_GSID_45360, MLS002153967, MLS006010796, SCHEMBL321657, CHEMBL1889091, DTXSID7045360, CTK8F8588, MolPort-003-912-067, MSIJLVMSKDXAQN-UHFFFAOYSA-N, HMS1570M13, Pharmakon1600-01500175, 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine hydrochloride, Tox21_110511, NSC169496, NSC756678, Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, hydrochloride, Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, hydrochloride, AKOS022181227, WLN: T6M DNTJ DYR&R DG &GH, API0001953, CCG-212523, HY-112067A, MCULE-3598783218, NSC-169496, NSC-756678, 4CA-0373, WLN: T6N DNTJ AYR&R DG& D &GH, LS-111212, CS-0062684, FT-0664522, FT-0697779, V1811, J-009887, SR-05000001920-3, 1-(p-Chlorobenzhydryl)-4-methylpiperazine hydrochloride, 1-(p-Chloro-.alpha.-phenylbenzyl)-4-methylpiperazine hydrochloride, 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine hydrochloride, Chlorcyclizine Hydrochloride 1.0 mg/ml in Methanol (as free base), Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, monohydrochloride, Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, monohydrochloride (9CI), Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, monohydrochloride (8CI), AKOS015896583, I06-2393

ID: 1421

InChIKey: MSJODEOZODDVGW-UHFFFAOYSA-N
SMILES: C1=COC(=C1)C2=NN3C(=N2)C4=C(C=CC(=C4)Cl)N=C3N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2690
synonyms found at PubChem are:
Cgs 15943, CGS-15943, 104615-18-1, CGS 15943A, CGS15943, 9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine, CHEMBL16687, MSJODEOZODDVGW-UHFFFAOYSA-N, 9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine, CPD000449284, 9-chloro-2-(2-furyl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine, [1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-, 9-Chloro-2-(2-furanyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-amine, 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine, (1,2,4)Triazolo(1,5-c)quinazolin-5-amine, 9-chloro-2-(2-furanyl)-, SMR000449284, SR-01000075210, [1,2,4]Triazolo[1,5-c]quinazolin-5-amine, 9-chloro-2-(2-furanyl)-, ACMC-20ddlj, Tocris-1699, Lopac-C-199, Nonnucleoside analog, 4, CGS-15943, solid, D0Q6WX, AC1L1E8T, AC1Q3MS4, Lopac0_000324, GTPL384, MLS000758223, MLS001423961, SCHEMBL1906971, SCHEMBL3844736, CHEBI:92849, CTK4A3171, DTXSID80146617, SYN5006, CHEBI:131351, MolPort-003-940-664, HMS2051C13, HMS3261A09, HMS3268O19, HMS3393C13, AOB33765, ZINC3872013, Tox21_500324, BDBM50004566, BN0142, PDSP1_001092, PDSP2_001076, AKOS015906465, CCG-100792, LP00324, NC00042, NCGC00015193-01, NCGC00015193-02, NCGC00015193-03, NCGC00015193-04, NCGC00015193-05, NCGC00015193-06, NCGC00015193-07, NCGC00025264-01, NCGC00025264-02, NCGC00025264-03, NCGC00025264-04, NCGC00261009-01, AS-16373, SAM001246973, LS-184727, B6835, C-199, EU-0100324, L000176, J-001205, SR-01000075210-1, SR-01000075210-3, BRD-K49049886-001-03-8, I14-22041, 9-Chloro-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine(CGS 15943), 9-chloro-2-(2-furanyl)-1,2,4-triazolo[1.5-c]quinazolin-5-amine, 9-chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine, 9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-amine, 9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine, [9-chloro-2-(furan-2-yl)-4H-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-amine, 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo (1,5-c)quinazolin-5-imine, 9-chloro-2-(2-furyl)-5-imino-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazoline, 9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine(CGS 15943)

ID: 1422

InChIKey: MSPWKPQQHHCXLR-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC4=C(C=C3OC)OCO4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 343083
synonyms found at PubChem are:
Cuneatin methyl ether, Maxima isoflavone G methyl ether, NSC382030, 4253-00-3, UNII-3RJ8MHV0O7, 3RJ8MHV0O7, 7-Methoxy-3-(6-methoxy-1,3-benzodioxol-5-yl)-4H-chromen-4-one, 7-methoxy-3-(6-methoxy-1,3-benzodioxol-5-yl)chromen-4-one, NSC 382030, Spectrum_000208, SpecPlus_000925, AC1L7XLN, Spectrum2_000401, Spectrum3_000255, Spectrum4_001550, Spectrum5_000120, BSPBio_001670, KBioGR_002020, KBioSS_000688, DivK1c_007021, SPBio_000322, SCHEMBL1675988, CHEMBL1976532, CHEBI:93558, KBio1_001965, KBio2_000688, KBio2_003256, KBio2_005824, KBio3_001170, DTXSID30195317, CCG-39974, LMPK12050088, NSC-382030, NCI60_003640, SR-05000002583, SR-05000002583-1, BRD-K89225759-001-01-3, 3-(6-Methoxy-1,3-benzodioxol-5-yl)-7-methoxychromone

ID: 1423

InChIKey: MTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES: C([C@H](C(=O)O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 71077
synonyms found at PubChem are:
D-serine, 312-84-5, (R)-2-amino-3-hydroxypropanoic acid, (2R)-2-amino-3-hydroxypropanoic acid, Serine D-form, (R)-Serine, Serine, D-, d-(+)-serine, H-D-Ser-OH, D-2-Amino-3-hydroxypropionic Acid, D-Serin, D-Ser, UNII-1K77H2Z9B1, EINECS 206-229-4, NSC 77689, (2R)-2-amino-3-hydroxy-propanoic acid, AI3-18476, CHEMBL285123, CHEBI:16523, MTCFGRXMJLQNBG-UWTATZPHSA-N, 1K77H2Z9B1, MFCD00004269, DSN, NCGC00094363-03, D-2-Amino-3-hydroxypropanoic acid, NSC77689, serine d-, [3h]-d-serine, (2R)-serine, Cycloserine Impurity 1, PubChem10704, 1pb8, AC1L2FHY, Biomol-NT_000197, D02UDJ, AC1Q4UB3, DSSTox_CID_21021, DSSTox_RID_79611, DSSTox_GSID_41021, Lopac0_001088, SCHEMBL43094, KSC222I6H, AC1Q5R15, BPBio1_001226, GTPL4171, Jsp005844, DTXSID9041021, BDBM23167, CTK1C2463, D-Serine, >=98% (TLC), (R)-2-amino-3-hydroxypropanoate, MolPort-000-158-483, HMS3263I18, ZINC895342, ACT00037, CS-D1751, Tox21_111269, Tox21_501088, ANW-27073, (R)-2-Amino-3-hydroxypropionic acid, AKOS006239590, AKOS015854121, (R)-2-Amino-3-hydroxy-propionic acid, CCG-205165, DB03929, LP01088, MCULE-3271603208, R(-)-2-Amino-3-hydroxypropionic acid, RP18848, RTC-066598, NCGC00094363-01, NCGC00094363-02, NCGC00094363-04, NCGC00094363-05, NCGC00094363-06, NCGC00261773-01, AC-24073, AJ-24179, AN-44227, AS-11730, BC676713, BR-46543, CAS-312-84-5, KB-50466, SC-09826, SY005114, D-Serine, Vetec(TM) reagent grade, 99%, AB0000919, AB1000355, DB-029708, HY-100808, LS-144974, TC-066598, AM20090441, EU-0101088, FT-0624388, FT-0688525, S0033, ST24026412, 12S845, C00740, S 4250, S-1330, Z1272739871, UNII-00PAR1C66F component MTCFGRXMJLQNBG-UWTATZPHSA-N, DD977692-169B-4266-88C3-E07F0B21A5BF, 2rcb, D-serine zwitterion, AC1OAGTP, 2v3u, CHEBI:35247, (2R)-2-ammonio-3-hydroxypropanoate, (2R)-2-azaniumyl-3-hydroxypropanoate, CJ-04469, ZB015025

ID: 1424

InChIKey: MTFCPNHRBINLRQ-UHFFFAOYSA-N
SMILES: CC(CNC1CCCCC1)OC(=O)C2=CC=CC=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 102426
synonyms found at PubChem are:
Hexylcaine hydrochloride, Hexylcaine HCl, 532-76-3, EINECS 208-544-2, D 109, 1-(Cyclohexylamino)-2-propanol benzoate (ester) hydrochloride, Cyclaine (TN), Benzoic acid, (2-(cyclohexylamino)-1-methyl)ethyl ester, hydrochloride, DSSTox_CID_25321, DSSTox_RID_80800, (2-(Benzoyloxy)propyl)cyclohexylammonium chloride, DSSTox_GSID_45321, 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester), hydrochloride, Hexylcaine hydrochloride [USP], AC1L2SRJ, NCGC00016495-01, CAS-532-76-3, SCHEMBL24192, MLS002154000, 532-77-4 (Parent), Hexylcaine Hydrochloride (1 g), CHEMBL1200715, DTXSID6045321, HMS1570M18, Tox21_110456, Tox21_110456_1, API0009282, CCG-220788, NCGC00179382-03, SMR001233331, LS-121962, D02454, SR-01000841236, SR-01000841236-2, 1-(cyclohexylamino)propan-2-yl benzoate hydrochloride

ID: 1425

InChIKey: MTJLQTFHJIHXIX-GDUXWEAWSA-N
SMILES: CC(C)[C@H]1C2=C(CC[C@@]1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)COC)C=C(C=C2)F.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 60662
synonyms found at PubChem are:
Mibefradil dihydrochloride, 116666-63-8, Mibefradil (dihydrochloride), UNII-842TUP3PQ8, Ro 40-5967, Mibefradil HCl, MIBEFRADIL 2HCL, Mibefradil dihydrochloride [USAN], 842TUP3PQ8, RO 40-5967/001, NCGC00094089-01, DSSTox_CID_24204, DSSTox_RID_80117, DSSTox_GSID_44204, (1S,2S)-(2-((3-(2-Benzimidazolyl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate, dihydrochloride, Mibefradil hydrochloride, Mibefradil dihydrochloride (USAN), Acetic acid, methoxy-, 2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride, (1S-cis)-, CAS-116666-63-8, Ro-405967-001, C29H38FN3O3.2ClH, Posicor (TN), Cerate 50, AC1L1TOB, AC1Q3ALR, Mibefradil-dihydrochloride, SCHEMBL120810, C29H38FN3O3.2HCl, CHEMBL1534525, DTXSID8044204, MolPort-003-666-827, MTJLQTFHJIHXIX-GDUXWEAWSA-N, AOB31771, BCP15607, Tox21_111244, Tox21_500748, 116644-53-2 (Parent), 3848AH, FD5011, HY-15553A, AKOS017343957, Tox21_111244_1, CCG-222052, CS-1189, LP00748, VA11293, NCGC00161420-06, NCGC00261433-01, Ro-40-5967, BC238043, LS-12466, EU-0100748, FT-0631084, Ro-40-5967/001, D05024, M 5441, C-23246, SR-01000075997, J-003469, SR-01000075997-1, (1s,2s)-(2-((3-(2-benzimidazolyl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride, (1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate dihydrochloride, (1S,2S)-2-(2-{[3-(1H-1,3-benzodiazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate dihydrochloride, (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetoacetate dihydrochloride, [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl] 2-methoxyacetate dihydrochloride, [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate dihydrochloride, Acetic acid, methyl-, 2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride, (1S-cis)-, Acetic acid,2-methoxy-,(1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenylester, hydrochloride (1:2), Ro 40-5967; (1S,2S)-2-[2[[3-(2-benzimidazolylpropyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride

ID: 1426

InChIKey: MTKNGOHFNXIVOS-UHFFFAOYSA-N
SMILES: C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 65335
synonyms found at PubChem are:
TICLOPIDINE HYDROCHLORIDE, 53885-35-1, Ticlopidine HCL, Ticlodix, Ticlodone, Ticlid, Panaldine, Tiklid, 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride, 53-32C, Ticlopidine (hydrochloride), UNII-A1L4914FMF, 4-C-32, EINECS 258-837-4, MLS000083578, A1L4914FMF, Tiklyd, SMR000048468, Ticlid (TN), 5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno-(3,2-c)pyridine hydrochloride, C14H15Cl2NS, Thieno(3,2-c)pyridine, 5-((2-chlorophenyl)methyl)-4,5,6,7-tetrahydro-, hydrochloride, W-105699, 5-[o-Chlorobenzyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine, 5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridinium chloride, CHEBI:9589, 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine hydrochloride, Thieno(3,2-c)pyridine, 4,5,6,7-tetrahydro-5-(o-chlorobenzyl)-, hydrochloride, TiclopidineHydrochloride, Aplaket, SR-01000003130, Ticlopidine, HCl, 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine;hydrochloride, Prestwick_502, Ticlopidine hydrochloride [USAN:JAN], PubChem22095, Ticlopidine hydrochloride [USAN:USP:JAN], C14H14ClNS.HCl, Opera_ID_1799, CHEMBL1717, SCHEMBL33596, MLS000028579, MLS001401394, Ticlopidine Hydrochloride,(S), AC1L232P, CTK8E8327, HY-B0153A, KS-00000XKJ, DTXSID80202141, MolPort-003-666-728, MTKNGOHFNXIVOS-UHFFFAOYSA-N, HMS1568I15, Pharmakon1600-01505677, BCP23429, BG0339, MFCD00079606, NSC759165, s1984, AKOS015905580, AC-8973, AN-7470, API0004830, CCG-101023, CS-1985, NC00273, NSC-759165, VA11875, Ticlopidine hydrochloride (JP17/USAN), AK-82274, AS-10890, CPD000048468, KB-81153, SAM001246558, SC-13802, BCP0726000288, 53885-35-1 (HCl), AB0008390, AB2000404, LS-152431, TC-030494, FT-0630664, ST24044168, D01028, J10052, M-1277, 885T351, SR-01000003130-6, Ticlopidine hydrochloride, analytical standard, for drug analysis, 5-(2-chloro-benzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride, Ticlopidine hydrochloride, European Pharmacopoeia (EP) Reference Standard, 5-(2-chloro-benzyl)-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine hydrochloride, 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno [3,2-c] pyridine hydrochloride, 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride, 5-[(2-chlorophenyl)methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine hydrochloride, 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridinehydrochloride, Ticlopidine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Ticlopid, AC1LCWC4, AKOS026749874, 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine; hydron; chloride, MolPort-000-785-528, MCULE-3408481955

ID: 1427

InChIKey: MTXSIJUGVMTTMU-UHFFFAOYSA-N
SMILES: C1CCNC(C1)C2=CN=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2181
synonyms found at PubChem are:
3-(piperidin-2-yl)pyridine, 13078-04-1, Anabasine, Neonicotine, DL-Anabasine, (+-)-Anabasine, 2-Pyridin-3-ylpiperidine, (+/-)-Anabasine, 3-(2-Piperidinyl)pyridine, 3-piperidin-2-ylpyridine, Pyridine, 3-(2-piperidinyl)-, 2-(3-Pyridyl)piperidine, 3-(2-piperidyl)pyridine, 2-(3-Pyridinyl)piperidine, (R,S)-ANABASINE, Anabasine hydrochloride, CHEMBL280963, CHEBI:28986, 1,2,3,4,5,6-Hexahydro-[2,3']Bipyridinyl, MTXSIJUGVMTTMU-UHFFFAOYSA-N, (R,S)-3-(2-Piperidinyl)Pyridine, L-3-(2'-Piperidyl)pyridine, PYRIDINE,3-(2-PIPERIDINYL)-, 40774-73-0, ( inverted exclamation markA) Anabasine, 2-(3'-Pyridyl) piperidine, Caswell No. 051, Pyridine, 3-(2-piperidinyl)-, (S)-, (+/-) Anabasine, MLS000737148, 2-(3-Pyridinyl)piperidine #, HSDB 3462, rac-Anabasine, EINECS 207-791-3, SR-01000765740, Pyridine, 3-(2-pyridyl) piperidine, EPA Pesticide Chemical Code 006001, BRN 0082637, (+/-)Anabasine, DL-ANABASIN, Spectrum_000023, Anabasine, (+/-), Anabasine, >=97%, SpecPlus_000616, AC1Q4WMP, DL-(NEONICOTINE), (.+/-.)-Anabasine, Prestwick0_000669, Prestwick1_000669, Prestwick2_000669, Spectrum2_001792, Spectrum3_001356, Spectrum4_000071, Spectrum4_001899, Spectrum5_000558, AC1L1D3R, AC1Q1HI3, AC1Q1HI5, AC1Q1HI6, AC1Q1HI7, 2-(Pyridin-3-yl)piperidine, BSPBio_003171, KBioGR_000621, KBioGR_002463, KBioSS_000383, DivK1c_006712, SCHEMBL117530, 2-(pyridin-3-yl)-piperidine, SPBio_001743, SPBio_002658, KBio1_001656, KBio2_000383, KBio2_002951, KBio2_005519, KBio3_002391, MolPort-000-145-770, HMS1570E19, HMS2269F13, rac.-2-(pyridin-3-yl)piperidine, ALBB-006068, KS-00002A7T, ANW-75339, BBL004609, BDBM50026461, MFCD00006370, PDSP1_000171, PDSP2_000170, SBB000142, STK028316, AKOS000276953, AKOS016050677, AB00736, CCG-208545, HY-W052144, MCULE-3752998129, PS-4547, SDCCGMLS-0066614.P001, SMP2_000070, NCGC00017173-02, NCGC00163365-01, AC-10023, AN-45293, KB-82230, LS-19276, SC-70240, SMR000528391, ST018408, AB0032882, DB-008085, LS-192593, TC-164084, CS-0044923, FT-0625434, FT-0695373, R1141, ST24041652, X6317, (+/-)-Anabasine, >=90% (TLC), liquid, 2-(3-PYRIDYL)PIPERIDINE/(-)-ANABASINE, C06180, (R,S)-3-(2-Piperidinyl)Pyridine Hydrochloride, J-005872, SR-01000765740-4, 3-[(2RS)-Piperidin-2-yl]pyridine ((RS)-Anabasine), BRD-A24284985-003-03-8, I14-13963, I14-23560, E48D8A38-D352-4AA3-BCCF-B14E46A0556C, F2158-0913

ID: 1428

InChIKey: MTZVJHSZYMWIAG-UHFFFAOYSA-N
SMILES: CCS(=O)(=O)NC1=CC=CC(=C1)C(=C2CCCCC2)C3=CN=CN3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6603710
synonyms found at PubChem are:
A-315456, CHEMBL362863, N-[3-(cyclohexylidene(1H-imidazol-4-ylmethyl)phenyl]ethanesulfonamide, NCGC00015076-01, AC1O7FZN, Lopac-A-6351, D0A0JU, Lopac0_000059, MLS002153477, CTK8F7477, HMS2235H14, HMS3260K19, HMS3370M22, ZINC9229227, Tox21_500059, BDBM50160163, CCG-204154, LP00059, NCGC00015076-02, NCGC00015076-03, NCGC00015076-04, NCGC00093573-01, NCGC00093573-02, NCGC00260744-01, SMR001230830, A-315456, >98% (HPLC), solid, EU-0100059, A 6351, SR-01000076218, SR-01000076218-1, N-[3-[cyclohexylidene(1H-imidazol-5-yl)methyl]phenyl]ethanesulfonamide, Ethanesulfonic acid {3-[cyclohexylidene-(1H-imidazol-4-yl)-methyl]-phenyl}-amide

ID: 1429

InChIKey: MUDRLQRJCGJJTB-UHFFFAOYSA-N
SMILES: C1C2=NOC(=O)N2C3=C(O1)C=CC(=C3)Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4551
synonyms found at PubChem are:
ns 2028, 204326-43-2, NS-2028, NS2028, 8-bromo-4h-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one, 4H-8-Bromo-1,2,4-oxadiazolo[3,4-d]benz[b][1,4]oxazin-1-one, 1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]benzoxazin-1-one,8-bromo-, 8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 8-bromobenzo[b][1,2,4]oxadiazolo[4,3-d][1,4]oxazin-1(4H)-one, SR-01000075533, Lopac-N-211, NS 2028, solid, D0U3YQ, AC1L1IF1, Lopac0_000922, CHEMBL507122, GTPL6554, ZINC7253, CTK4E4216, MolPort-003-958-944, MUDRLQRJCGJJTB-UHFFFAOYSA-N, BDBM113770, HMS3262J06, HMS3649M06, AC1Q2748, Tox21_500922, MFCD01530052, AKOS024458199, CCG-205004, EH00002, LP00922, NCGC00015722-01, NCGC00015722-02, NCGC00015722-03, NCGC00015722-04, NCGC00094233-01, NCGC00094233-02, NCGC00261607-01, RT-014759, EU-0100922, N-211, NS2028 (1), SR-01000075533-1, SR-01000075533-5, BRD-K03645807-001-01-7, 4-H-Bromo-1,2,4-oxadiazole(3,4-alpha)benz(b)oxazin-1-one, 8-Bromo-4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one; NS2028, 28N

ID: 1430

InChIKey: MUMGGOZAMZWBJJ-DYKIIFRCSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6013
synonyms found at PubChem are:
testosterone, 58-22-0, Testosteron, Androderm, Mertestate, Sustanon, Testoderm, Virosterone, Androlin, Oreton, Testim, AndroGel, Synandrol F, Testosteroid, Andronaq, Andropatch, Andrusol, Homosteron, Homosterone, Malerone, Orquisteron, Perandren, Primotest, Primoteston, Sustanone, Testandrone, Testobase, Testogel, Testopropon, Testoviron, Testrone, trans-Testosterone, Relibra, Teslen, Testryl, Testiculosterone, Cristerona T, Cristerone T, Testoviron T, Testosteronum, Testostosterone, Neotestis, Testosterona, Testoviron Schering, Geno-cristaux gremy, LibiGel, 17beta-Hydroxyandrost-4-en-3-one, Neo-Hombreol F, Oreton-F, Testoject-50, Striant, Testolin, Andro 100, Testosterone hydrate, Percutacrine androgenique, Neo-testis, Sustason 250, Testoderm Tts, beta testosterone, Malestrone (amps), Intrinsa, Virormone, Malogen, aquaspension injection, Testosteronum [INN-Latin], Testosterona [INN-Spanish], Testro AQ, Androst-4-en-17beta-ol-3-one, Testopel Pellets, Oreton F, CDB 111C, Testosterone and its esters, 17beta-Hydroxy-4-androsten-3-one, 7-beta-Hydroxyandrost-4-en-3-one, COL 1621, delta4-Androsten-17beta-ol-3-one, 17beta-Hydroxyandrost-4-ene-3-one, 17-beta-Hydroxyandrost-4-en-3-one, Halotensin, Androsorb, Testaqua, 4-Androsten-17beta-ol-3-one, CP 601B, T-Cypionate, Testosterone [INN:BAN], Malogen in Oil, Virilon IM, 17-Hydroxy-(17beta)-androst-4-en-3-one, 17beta-Hydroxy-delta(sup4)-androsten-3-one, delta(sup 4)-Androsten-17(beta)-ol-3-one, Testrin-P.A, 17-Hydroxy-(17-beta)-androst-4-en-3-one, Androderm (TN), UNII-3XMK78S47O, Androgel (TN), Andronate 100, Andronate 200, Andropository 200, CCRIS 574, Striant (TN), Testamone 100, 17-beta-Hydroxy-delta(sup 4)-androsten-3-one, AA 2500, Androst-4-en-3-one, 17beta-hydroxy-, Testim (TN), Androst-4-en-3-one, 17-hydroxy-, (17beta)-, Everone 200, Androst-4-en-3-one, 17-beta-hydroxy-, Andryl 200, CHEBI:17347, HSDB 3398, Scheinpharm Testone-Cyp, Testred Cypionate 200, NSC 9700, EINECS 200-370-5, Testosterone (JAN/USP), (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, (17beta)-17-Hydroxyandrost-4-en-3-one, 3XMK78S47O, Testosterone [Androgenic steroids, anabolic], 4-androstene-17beta-ol-3-one, 17b-hydroxy-4-androsten-3-one, delta4-androsten-17b-ol-3-one, MUMGGOZAMZWBJJ-DYKIIFRCSA-N, Androst-4-en-3-one, 17-hydroxy-, (17-beta)-, CMC_13449, Androst-4-en-3-one, 17-hydroxy-, (17b)-, Fortesta, Nasobol, Natesto, Vogelxo, Axiron, Tefina, CompleoTRT, Androgel 1%, 17.beta.-Testosterone, SMR000058344, Bio-T-Gel, Androgel 1.62%, Androst-4-en-3-one, 17-hydroxy-, (17.beta.)-, Androst-4-en-3-on-17B-ol, CHEMBL386630, component of Duogen (Salt/Mix), component of Tostrex (Salt/Mix), component of Di-Met (Salt/Mix), component of Intrinsa (Salt/Mix), 4-Androsten-17.beta.-ol-3-one, 4-Androsten-3-one-17.beta.-ol, Tlando, component of Di-Genik (Salt/Mix), 4-Androsten-3-one, 17b-hydroxy-, Testosterone [USP:INN:BAN], component of Mal-O-Fem (Salt/Mix), LPCN 1021, Testosterone, 1, 3kdm, 17-.beta.-Hydroxyandrost-4-en-3-one, NCGC00091018-01, CPD000058344, 17beta-testosterone, Testosterone solution, Axiron (TN), mpp10, 17.beta.-Hydroxy-.DELTA.4-androsten-3-one, Androderm, Delatestryl, 17-Hydroxyandrost-4-en-3-one, (17.beta.)-, Testosterone, >=98%, DSSTox_CID_2371, D06XMU, Epitope ID:135865, EC 200-370-5, AC1L1LM0, SCHEMBL8452, 4-androsten-17-ol-3-one, DSSTox_RID_76563, DSSTox_GSID_22371, MLS000563091, MLS001032098, MLS001306401, MLS001424262, MLS002174283, BIDD:ER0555, BDBM8885, GTPL2858, 17-Hydroxy-4-androsten-3-one, DTXSID8022371, 17beta-hydroxy-4-androsten-3one, Testosterone, cell culture tested, 1i37, HMS2052N11, HMS2272B03, HMS2272P03, (8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, 17beta-Hydroxy-3-oxo-4-androstene, Tox21_200689, HY-15554A, LMST02020002, RB3046, AKOS015894897, ZINC118912393, CCG-101189, CS-1415, DB00624, MCULE-1294118086, NC00439, RP29985, CAS-58-22-0, Testosterone 1.0 mg/ml in Acetonitrile, (17?)-17-Hydroxyandrost-4-en-3-one, NCGC00258243-01, AC-14899, AN-23597, BC208298, SC-15109, SMR001261453, Testosterone, purum, >=99.0% (HPLC), LS-148813, Testosterone 100 microg/mL in Acetonitrile, BIM-0061761.0001, C00535, D00075, S00309, W-5033, AB00973630-03, Testosterone, VETRANAL(TM), analytical standard, 003T654, Androst-4-en-3-one, 17-hydroxy, (17.beta.)-, C-18145, Q-101251, B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E, Testosterone, European Pharmacopoeia (EP) Reference Standard, (8alpha,10alpha,13alpha,14beta,17alpha)-17-hydroxyandrost-4-en-3-one, Testosterone solution, 1.0 mg/mL in 1,2-dimethoxyethane, drug standard, Testosterone; 4-Androsten-17?-ol-3-one; 17?-Hydroxy-4-androsten-3-one, Testosterone for impurity D identification, European Pharmacopoeia (EP) Reference Standard, Testosterone for system suitability, European Pharmacopoeia (EP) Reference Standard, (1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-6-en-5-one, (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, 1050678-68-6, Testosterone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material

ID: 1431

InChIKey: MUQNGPZZQDCDFT-JNQJZLCISA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CCl)C)O)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 443943
synonyms found at PubChem are:
halcinonide, 3093-35-4, Halciderm, Halcimat, Halog, Halcinonida, Halcinonidum, Alcinonide, HALOG-E, UNII-SI86V6QNEG, SI86V6QNEG, Betacorton, Ascochrom, Halcort, Volog, Halcinonidum [INN-Latin], Halcinonida [INN-Spanish], C24H32ClFO5, DSSTox_CID_25375, DSSTox_RID_80836, DSSTox_GSID_45375, SQ 18566, SQ-18,566, EINECS 221-439-6, BRN 1358242, Halcinonid, Adcortin, NCGC00016621-01, (11?,16?)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregn-4-ene-3,20-dione, 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione cyclic 16,17-acetal with acetone, Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-, CAS-3093-35-4, Prestwick_1069, Halog (TN), Halcinonide [USAN:USP:INN:BAN:JAN], Prestwick0_000655, Prestwick1_000655, Prestwick2_000655, Prestwick3_000655, D06IIB, AC1L9FG3, SCHEMBL4335, BSPBio_000689, 5-19-06-00301 (Beilstein Handbook Reference), MLS002153935, Halcinonide (JAN/USP/INN), SPBio_002610, BPBio1_000759, CHEMBL1200845, DTXSID6045375, CHEBI:31663, MolPort-005-937-976, HMS1570C11, HMS2097C11, HMS2230O07, HMS3714C11, HY-B0877, Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy-, cyclic16,17-acetal with acetone, ZINC4213474, Tox21_110530, s4098, AKOS015962797, Tox21_110530_1, AC-1114, AC-1774, CCG-220655, DB06786, NCGC00179475-01, NCGC00179475-03, AN-14636, BC214763, P753, SC-80633, SMR001233277, SO-18566, SQ-18566, D01308, 093H354, Q-201180, BRD-K81709173-001-03-8, Halcinonide, United States Pharmacopeia (USP) Reference Standard, (11|A,16|A)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione, (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

ID: 1432

InChIKey: MUUQATOBEVXSBH-QTVDCKGISA-N
SMILES: CC(=O)O[C@@H]1CC2[C@]([C@@H]3[C@@H](O3)C(=O)C2(C)C)(C4[C@@]1(C5=CC(=O)O[C@H]([C@@]5(CC4)C)C6=COC=C6)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708638
synonyms found at PubChem are:
Spectrum_000547, SpecPlus_000289, Spectrum2_000335, Spectrum3_000084, Spectrum4_001368, Spectrum5_000016, BSPBio_001608, KBioGR_001636, KBioSS_001027, SPECTRUM100439, DivK1c_006385, SPBio_000369, SCHEMBL14197022, KBio1_001329, KBio2_001027, KBio2_003595, KBio2_006163, KBio3_000688, CCG-38610, SDCCGMLS-0066350.P001, NCGC00179155-01, 1 (2)alpha-EPOXYDEOXYDIHYDROGEDUNIN

ID: 1433

InChIKey: MVAWJSIDNICKHF-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 903
synonyms found at PubChem are:
N-Acetyl-5-hydroxytryptamine, N-acetylserotonin, 1210-83-9, N-ACETYL SEROTONIN, Normelatonin, N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide, O-Demethylmelatonin, 5-Hydroxy-N-acetyltryptamine, acetylserotonin, UNII-P4TO3C82WV, 5-Hydroxymelatonin, N-(2-(5-Hydroxy-1H-indol-3-yl)ethyl)acetamide, 3-(2-Acetamidoethyl)-5-hydroxyindole, Acetyl-5-hydroxy-tryptamine, P4TO3C82WV, CHEMBL33103, CHEBI:17697, MVAWJSIDNICKHF-UHFFFAOYSA-N, Acetamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-, A-1300, Desmethylmelatonin, N-acetyl-serotonin, Serotonin,N-acetyl, N-acetyl serotonine, EINECS 214-916-5, N-acetyl-5-HT, Serotonin, N-acetyl-, Spectrum_000369, AC1L1AAB, Spectrum3_001871, Spectrum4_001268, Spectrum5_000975, Lopac-A-1824, ACMC-1BO7I, D00PDI, D0F9ZW, AC1Q5P6T, Acetamide, N-[2-(5-hydroxyindol-3-yl)ethyl]-, Lopac0_000044, BSPBio_003342, KBioGR_001856, KBioSS_000849, N-Acetyltryptamine,5-Hydroxy, MLS000859911, DivK1c_000668, SCHEMBL422165, SPECTRUM1500700, AC1Q1L67, AC1Q1L68, GTPL5451, N-Acetylserotonin; Normelatonin, BDBM29612, CTK8A9435, HMS502B10, KBio1_000668, KBio2_000849, KBio2_003417, KBio2_005985, KBio3_002844, N-Acetylserotonin|||Normelatonin, ZINC66104, DTXSID00153106, Tryptamine, N-acetyl-5-hydroxy-, MolPort-001-736-385, NINDS_000668, HMS2235E22, HMS3260I09, HMS3372M05, N-Acetyl-5-hydroxytryptamine, 99%, Tox21_500044, 7506AH, ANW-17558, MFCD00005656, PDSP1_001650, PDSP1_001789, PDSP1_001790, PDSP1_001827, PDSP2_001634, PDSP2_001772, PDSP2_001773, PDSP2_001810, AKOS004120085, API0003477, CCG-204140, DB04275, LP00044, MCULE-4114943625, VZ33043, IDI1_000668, NCGC00015039-01, NCGC00015039-02, NCGC00015039-03, NCGC00015039-04, NCGC00015039-05, NCGC00015039-06, NCGC00015039-07, NCGC00093558-01, NCGC00093558-02, NCGC00093558-03, NCGC00093558-04, NCGC00093558-05, NCGC00260729-01, CC-32273, KB-79213, SMR000326772, ST092857, ZB002533, DB-007732, HY-107854, TC-106303, A1277, CS-0030736, EU-0100044, FT-0080684, FT-0629855, N-[2-(5-hydroxyindol-3-yl)ethyl]acetamide, A 1824, C00978, A804654, C-11937, L000433, N-(2-(5-hydroxy-1H-indol-3-yl)ethyl) acetamide, SR-01000075660, Acetamide,N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-, I10-0829, N-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-acetamide, N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide #, N-[2-(5-oxidanyl-1H-indol-3-yl)ethyl]ethanamide, SR-01000075660-1, BRD-K26140483-001-01-3, N-Acetyl-5-hydroxytryptamine, >=99% (TLC), powder, 7D6F82BE-C205-424F-9F26-65CE227610C0

ID: 1434

InChIKey: MVNJNWNFUCRWBW-NFAWXSAZSA-N
SMILES: C[C@]12CC[C@H](C[C@H]1CCC3=CC=CC=C23)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6708760
synonyms found at PubChem are:
3alpha-HYDROXY-4,4-BISNOR-8,11,13-PODOCARPATRIENE, Spectrum_000701, SpecPlus_000741, AC1O8FNE, Spectrum2_000301, Spectrum3_000127, Spectrum4_001405, Spectrum5_000170, BSPBio_001774, KBioGR_001790, KBioSS_001181, SPECTRUM100618, DivK1c_006837, SPBio_000262, CHEMBL3039165, SCHEMBL12998486, KBio1_001781, KBio2_001181, KBio2_003749, KBio2_006317, KBio3_000934, CCG-39939, (2R,4aS,10aR)-4a-methyl-2,3,4,9,10,10a-hexahydro-1H-phenanthren-2-ol

ID: 1435

InChIKey: MVOWQBJZZKOQNU-UHFFFAOYSA-N
SMILES: C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C(=O)COC4=CC=C(C=C4)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 161803
synonyms found at PubChem are:
Fipexide hydrochloride, Attentil, Vigilor, Fipexide HCl, Fipexidum hydrochloride, 34161-23-4, UNII-NQ702L425I, EINECS 251-856-9, BP 662, C20H21ClN2O4.HCl, NQ702L425I, NCGC00095024-01, 1-(1,3-Benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)acetyl)piperazine hydrochloride, DSSTox_CID_27446, DSSTox_RID_82352, DSSTox_GSID_47446, 1-(1,3-Benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)acetyl)piperazinium chloride, Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)acetyl)-, monohydrochloride, SR-01000806671, CAS-34161-23-4, Prestwick_601, AC1Q3BFC, AC1L4Q3Z, MLS002154256, SCHEMBL467102, SPECTRUM1503222, CHEMBL1377408, DTXSID6047446, CTK8F9763, MolPort-003-981-176, HMS1568L18, HMS1922K07, Pharmakon1600-01503222, Tox21_111394, Tox21_302469, BG0453, CCG-39316, NSC758407, Piperazine, 1-((p-chlorophenoxy)acetyl)-4-piperonyl-, monohydrochloride, piperazine, 1-((p-chlorophenoxy)acetyl)-4-piperonyl-, monohydrochloride(8ci), Tox21_111394_1, NSC-758407, ACM34161234, NCGC00016825-06, NCGC00095024-02, NCGC00256757-01, H958, SMR001233517, Fipexide hydrochloride, analytical standard, LS-110313, J-019471, SR-01000806671-3, SR-01000806671-4, 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone hydrochloride, Piperazine, 1-((p-chlorophenoxy)acetyl)-4-piperonyl-, monohydrochloride (8CI)

ID: 1436

InChIKey: MVOYJPOZRLFTCP-UHFFFAOYSA-N
SMILES: CN1C(=O)C2=C(NC1=O)N=CN2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 80220
synonyms found at PubChem are:
1-Methylxanthine, 6136-37-4, 1-Methyl-3,7-dihydro-purine-2,6-dione, 1-Methyl-1H-purine-2,6(3H,7H)-dione, Methylxanthine, Xanthine, 1-methyl-, UNII-7EE8WCA32U, 2,6-Dihydroxy-1-methylpurine, CCRIS 5816, 1-methyl-7H-xanthine, EINECS 228-108-5, 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-, 7EE8WCA32U, CHEMBL1250, 2,6 Dihydroxy-1-methylpurine, 3,7-Dihydro-1-methyl-1H-purine-2,6-dione, CHEBI:68444, MVOYJPOZRLFTCP-UHFFFAOYSA-N, 1-methyl-3,7-dihydropurine-2,6-dione, 1-methyl-3,9-dihydropurine-2,6-dione, 1-Methyl-3,7-dihydro-1H-purine-2,6-dione, 1-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, SMR000857247, PubChem23793, Spectrum_000233, SpecPlus_000793, Spectrum2_001195, Spectrum3_001714, Spectrum4_001810, Spectrum5_000519, 1-Methylxanthine, 98%, AC1L2Z0D, Oprea1_807160, SCHEMBL10996, BSPBio_003328, KBioGR_002423, KBioSS_000713, MLS001333143, MLS001333144, DivK1c_006889, SPECTRUM2300329, SPBio_001269, SCHEMBL9467551, SCHEMBL12037451, 1-Methyl-1H-purine-2,6-diol, BDBM82020, CTK8B5451, KBio1_001833, KBio2_000713, KBio2_003281, KBio2_005849, KBio3_002548, DTXSID30210271, MolPort-003-665-631, HMS2233F07, HMS3371B10, KS-00000MC9, AN-666, ANW-48772, CAS_80220, CCG-38576, MFCD00005561, NSC_80220, ZINC13517144, AKOS006229655, AKOS015919510, CS-W008449, FCH2258284, GS-3924, MCULE-9373290148, RP22872, SDCCGMLS-0066848.P001, 1-Methylxanthine, >=97.0% (HPLC), NCGC00095783-01, 1-Methyl-3,9-dihydro-purine-2,6-dione, AC-28113, AJ-64022, AK-48387, BR-48387, CC-04826, 1-methyl-1,3,7-trihydropurine-2,6-dione, AB0025823, AX8059684, DB-025633, LS-162543, ST2408818, 4CH-014597, FT-0635988, M2432, ST50298911, W7363, C-1023, C16358, 1-Methyl-3,7-dihydro-1H-purine-2,6-dione #, 136M374, C-30337, 2,6- paragraph signthornoC>>u-1-(1/4)x>>uaNssE, 1-Methyl-3,9-dihydro-purine-2,6-dione(1-methyl xanthine), 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-;1-Methyl-3,7-dihydro-1H-purine-2,6-dione

ID: 1437

InChIKey: MWBPRDONLNQCFV-UHFFFAOYSA-N
SMILES: CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5543
synonyms found at PubChem are:
triallate, Tri-allate, 2303-17-5, Triallat, Dipthal, Triamyl, Avadex BW, Far-Go, Triallat [German], Caswell No. 870A, Tri-allate [BSI:ISO], Diisopropyltrichloroallylthiocarbamate, NSC 379698, UNII-A9S097HS99, CCRIS 5383, CP 23426, HSDB 1780, S-(2,3,3-Trichloroallyl) N,N-diisopropylthiocarbamate, 2,3,3-Trichloroallyl diisopropylthiocarbamate, EINECS 218-962-7, RCRA waste no. U389, EPA Pesticide Chemical Code 078802, 2,3,3-Trichloroallyl N,N-diisopropylthiocarbamate, Carbamic acid, diisopropylthio-, S-(2,3,3-trichloroallyl) ester, BRN 1875853, S-2,3,3-Trichloroallyl N,N-diisopropylthiocarbamate, Carbamothioic acid, bis(1-methylethyl)-, S-(2,3,3-trichloro-2-propenyl) ester, 2,3,3-Trichloro-2-propene-1-thiol diisopropylcarbamate, 2-Propene-1-thiol, 2,3,3-trichloro-, diisopropylcarbamate, CHEBI:81978, Thiocarbamic acid, N-diisopropyl-, S-2,3,3-trichloroallyl ester, S-2,3,3-Trichloroallyl diisopropylthiocarbamate, A9S097HS99, N-Diisopropylthiocarbamic acid S-2,3,3-trichloro-2-propenyl ester, S-(2,3,3-Trichloroallyl)diisopropylthiocarbamate, S-(2,3,3-Trichloroallyl) diisopropylthiocarbamate, 2,3,3-Trichlorallyl-N,N-(diisopropyl)-thiocarbamat, S-2,3,3-Trichloroallyl-N,N-diisopropylthiolcarbamate, 2,3,3-Trichlorallyl-N,N-(diisopropyl)-thiocarbamat [German], Diisopropylthiocarbamic acid S-(2,3,3-trichloroallyl) ester, N,N-Diisopropyl-2,3,3-trichlorallyl-thiolcarbamat [German], S-(2,3,3-Trichloro-2-propenyl) bis(1-methylethyl)carbamothioate, S-(2,3,3-Trichloro-2-propenyl) bis(1-methylethyl)carbamothiote, DSSTox_CID_4344, Bis(1-methylethyl)carbamothioic acid, S-(2,3,3-trichloro-2-propenyl)ester, Carbamothioic acid, bis(1-methylethyl)-, S-(2,3,3-trichloro-2-propenyl)ester, DSSTox_RID_77375, DSSTox_GSID_24344, S-(2,3,3-trichloroprop-2-enyl) N,N-di(propan-2-yl)carbamothioate, CAS-2303-17-5, Showdown, S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate, Avadex BE, Far-Go/Avadex BW, Spectrum_001889, SpecPlus_000510, AC1L1KKW, AC1Q1PWE, Spectrum2_001844, Spectrum3_000845, Spectrum4_000685, Spectrum5_002006, AC1Q3FU9, SCHEMBL62793, BSPBio_002429, KBioGR_001149, KBioSS_002419, Triallat, analytical standard, N,N-Diisopropyl-2,3,3-trichlorallyl-thiolcarbamat, DivK1c_006606, SPBio_001628, CHEMBL1884767, DTXSID5024344, CTK8E7244, KBio1_001550, KBio2_002413, KBio2_004981, KBio2_007549, KBio3_001929, S-(2,3,3-Trichloroallyl) diisopropylthiocarbamate (8CI), MWBPRDONLNQCFV-UHFFFAOYSA-N, ZINC1590916, Tox21_201817, Tox21_300671, CCG-39382, NSC379698, AKOS016011225, S-(2,3,3-Trichloro-2-propenyl) bis(1-methylethyl)carbamothioate (9CI), ACM2303175, NSC-379698, Triallate 10 microg/mL in Cyclohexane, NCGC00168339-01, NCGC00168339-02, NCGC00168339-03, NCGC00168339-04, NCGC00254579-01, NCGC00259366-01, Triallate 100 microg/mL in Acetonitrile, AN-50671, CJ-25445, LS-49397, TR-030691, FT-0748886, Triallat, PESTANAL(R), analytical standard, C18813, S-2,3,3-trichloroallyl diisopropylcarbamothioate, N,N-Diisopropyl-2,3,3-trichlorallyl-thiolcarbamate, BRD-K64698045-001-02-2, S-2,3,3-trichloroallyl di-isopropyl (thiocarbamate), S-(2,3,3-trichloroallyl) N,N-diisopropylcarbamothioate, S-(2,3,3-Trichloro-2-propenyl) diisopropylthiocarbamate #, N,N-bis(propan-2-yl)[(2,3,3-trichloroprop-2-en-1-yl)sulfanyl]formamide

ID: 1438

InChIKey: MWHLCFYPFGFBQO-UHFFFAOYSA-N
SMILES: C1=C(NC=N1)CC(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 145685
synonyms found at PubChem are:
3251-69-2, 4-Imidazoleacetic acid hydrochloride, 2-(1H-imidazol-5-yl)acetic acid hydrochloride, Imidazole-4-acetic acid hydrochloride, 2-(1H-Imidazol-4-Yl)Acetic Acid Hydrochloride, 4-Imidazoleacetic acid HCl, imidazoleacetic acid hydrochloride, UNII-ET7A74ROAO, 4-Imidazoleaceticacidhydrochloride, ET7A74ROAO, Imidazole-4-Acetic Acid HCl, 1H-Imidazole-4-acetic acid, monohydrochloride, GEO-01571, 1H-imidazole-4-acetic acid hydrochloride, 1H-Imidazole-5-aceticacid, hydrochloride (1:1), 30581-89-6 (Parent), EINECS 221-840-6, zlchem 1218, AC1L3ROX, I4AA HYDROCHLORIDE, ACMC-1CP7C, SCHEMBL45374, 4-Imidazoleacetic acid, HCl, KSC224S9N, MLS000859604, IMIDAZOLEACETIC ACID HCl, SCHEMBL8482521, CHEMBL1256325, CTK1C4996, DTXSID00186237, ZLD0687, MolPort-000-004-284, MolPort-003-928-018, MWHLCFYPFGFBQO-UHFFFAOYSA-N, ACT05700, BCP18582, imidazole-4acetic acid hydrochloride, Tox21_500609, 4-imidazole acetic acid hydrochloride, ANW-43717, ANW-53804, imidazol4-ylacetic acid hydrochloride, MFCD00012698, SBB003940, 2-imidazol-5-ylacetic acid, chloride, 4-Carboxymethylimidazole Hydrochloride, (3H-Imidazol-4-yl)-acetic acid HCl, AKOS015849572, AKOS015919988, ACM3251692, CCG-221913, CHM0143986, CS-W007686, LP00609, OR51912, RTR-013667, TRA0090998, VI10202, (4-Imidazolyl)acetic acid hydrochloride, 1H-imidazole 4-acetic acid hydrochloride, 2-(1H-Imidazol-5-yl)acetic acid, HCl, imidazole-4-acetic acid monohydrochloride, NCGC00093984-01, NCGC00261294-01, 1H-imidazol-4-ylacetic acid hydrochloride, 1H-imidazol-5-ylacetic acid hydrochloride, 1H-Imidazole-5-acetic acid hydrochloride, AK-35977, BR-35977, BR-46387, DS-12814, Imidazole-4(5)-acetic Acid Hydrochloride, SC-13980, SMR000326676, 4-Imidazoleacetic acid hydrochloride, 98%, AB0024208, AX8009601, DB-048233, KB-202541, ST2415999, TC-142549, TR-013667, (1H-imidazol-4-yl)acetic acid hydrochloride, 4CH-012410, A5821, AM20090474, EU-0100609, FT-0618754, I0229, ST50407308, W5432, (1H-imidazol-4-yl)-acetic acid hydrochloride, KS-00001055, (1H-Imidazol-4-yl)-acetic acid; hydrochloride, C-6205, H57492, I 0375, S04-062, SR-01000075928, S04-0062, SR-01000075928-1, (3H-IMIDAZOL-4-YL)-ACETIC ACID HYDROCHLORIDE, Z2738358143, Imidazole-4-acetic acid monohydrochloride, 97% 1g

ID: 1439

InChIKey: MXJWRABVEGLYDG-UHFFFAOYSA-N
SMILES: CCCCOC1=CC=C(C=C1)CC(=O)NO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2466
synonyms found at PubChem are:
bufexamac, 2438-72-4, Bufexamic acid, Parfenac, 2-(4-Butoxyphenyl)-N-hydroxyacetamide, Droxaryl, Feximac, Malipuran, Mofenar, Parfenal, Bufexamaco, Bufexamacum, Flogicid, Norfemac, Paraderm, Anderm, 4-Butoxy-N-hydroxybenzeneacetamide, p-Butoxyphenylacetohydroxamic acid, 4-Butoxyphenylacetohydroxamic acid, Flogocid N plastigel, Acide p-butoxyphenylacethydroxamique, 2-(p-Butoxyphenyl)-acetohydroxamic acid, Bufessamac [DCIT], Bufexamacum [INN-Latin], Bufexamaco [INN-Spanish], 2-(p-Butoxyphenyl)acetohydroxamic acid, Benzeneacetamide, 4-butoxy-N-hydroxy-, CP 1044 J3, UNII-4T3C38J78L, CP 1044, CHEBI:31317, Bufexamac [INN:BAN:DCF:JAN], EINECS 219-451-1, ACETOHYDROXAMIC ACID, 2-(p-BUTOXYPHENYL)-, 2-(4-butoxyphenyl)acetohydroxamic acid, BRN 2646848, CHEMBL94394, MLS000028409, Acide p-butoxyphenylacethydroxamique [French], MXJWRABVEGLYDG-UHFFFAOYSA-N, 4T3C38J78L, CP-1044-J3, J3, 2-(4-butoxyphenyl)ethanehydroxamic acid, NCGC00016611-01, SMR000058407, CAS-2438-72-4, DSSTox_CID_25368, DSSTox_RID_80831, DSSTox_GSID_45368, Bufessamac, Droxarol, ML392, SR-01000003067, bufexamicacid, p-Butoxyphenylacethydroxamic Acid, Bufexamac,(S), Prestwick_676, Anderm (TN), Spectrum_001754, Bufexamac (JAN/INN), AC1L1DQQ, AC1Q2XHW, AC1Q5QCV, Opera_ID_1503, Prestwick0_000243, Prestwick1_000243, Prestwick2_000243, Prestwick3_000243, Spectrum2_001457, Spectrum3_000938, Spectrum4_001037, Spectrum5_001117, D02HXS, Epitope ID:180855, cid_2466, cp1044j3, REGID_for_CID_2466, SCHEMBL25215, BSPBio_000026, KBioGR_001593, KBioSS_002234, cp1044, MLS001148632, Bufexamac, analytical standard, Butoxyphenylacethydroxamic Acid, DivK1c_000108, SPECTRUM1502003, SPBio_001353, SPBio_002245, BPBio1_000030, GTPL7498, 4-butoxyphenylacetohydroxamicacid, DTXSID7045368, CTK8F8354, HMS500F10, KBio1_000108, KBio2_002234, KBio2_004802, KBio2_007370, KBio3_001976, acidep-butoxyphenylacethydroxamique, MolPort-001-846-212, NINDS_000108, 4-butoxy-n-hydroxy-benzeneacetamid, HMS1568B08, HMS1921B18, HMS2095B08, HMS2235I13, HMS3371K16, HMS3656H16, HMS3712B08, KUC105648N, Pharmakon1600-01502003, ACT07664, HY-B0494, KS-00000XL3, ZINC3871797, Para-butoxyphenylacetohydroxamic acid, Tox21_110522, BDBM50015144, BG0111, CCG-39191, NSC758153, s3023, SBB056991, 2-(p-butoxyphenyl)-acetohydroxamicaci, Bufexamac 1.0 mg/ml in Acetonitrile, AKOS015895401, KUC105648N-02, KUC105648N-03, Tox21_110522_1, API0001778, CS-2615, DB13346, KSC-10-210, MCULE-8477153639, NSC-758153, IDI1_000108, KSC-390-003, NCGC00016611-02, NCGC00016611-03, NCGC00016611-04, NCGC00016611-05, NCGC00016611-06, NCGC00016611-07, NCGC00016611-09, NCGC00016611-10, NCGC00021813-03, NCGC00021813-04, 2-(4-Butoxy-phenyl)-N-hydroxy-acetamide, 2-(4-Butoxyphenyl)-N-hydroxyacetamide #, AC-18729, AJ-46354, AN-50915, AS-12207, LS-13084, SC-13711, KSC-285-073-1, SBI-0051694.P002, AB0005884, AX8118941, KB-222467, AB00052252, B1443, B4179, FT-0603607, ST24027540, ST50993888, Benzeneacetamide, 4-butoxy-N-hydroxy- (9CI), D01271, J10267, K-6542, AB00052252_19, AB00052252_20, I06-0661, J-015485, SR-01000003067-3, SR-01000003067-4, BRD-K36660044-001-15-0, Bufexamac, European Pharmacopoeia (EP) Reference Standard, A4Z

ID: 1440

InChIKey: MXWJVTOOROXGIU-UHFFFAOYSA-N
SMILES: CCNC1=NC(=NC(=N1)Cl)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2256
synonyms found at PubChem are:
atrazine, 1912-24-9, Gesaprim, Chromozin, Oleogesaprim, Aktikon, Argezin, Atazinax, Atranex, Atrasine, Atrazin, Fenamin, Fenatrol, Gesoprim, Hungazin, Pitezin, Primatol, Primaze, Radazin, Strazine, Zeazine, Aatrex, Candex, Cyazin, Inakor, Vectal, Wonuk, Zeazin, Cekuzina-T, Actinite PK, Aktinit A, Atratol A, Aktikon PK, Aktinit PK, Weedex A, Crisatrina, Crisazine, Fenamine, Aatram, Akticon, Atrataf, Atratol, Griffex, Radizin, Zeapos, Atred, Atrex, Primatol A, Hungazin PK, Aatrex nine-O, Vectal SC, Herbatoxol, Zeopos, Triazine A 1294, Aatrex 4L, Farmco atrazine, Gesaprim 50, Aatrex 80W, Aneldazin, Gesaprin, Radizine, Azoprim, Maizina, Geigy 30,027, Shell atrazine herbicide, 2-Chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine, Hungazin (VAN), Aatram 20G, Ceasin 50, Crisamina, Farmozine, Laddock, Mebazine, Fogard, 2-Chloro-4-ethylamino-6-isopropylamino-s-triazine, 1,3,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1-methylethyl)-, 2-Chloro-4-ethylamineisopropylamine-s-triazine, 2-Ethylamino-4-isopropylamino-6-chloro-s-triazine, A 361, Aatrex 4LC, Atrazine [ANSI:BSI:ISO], Caswell No. 063, Atraflow, Primoleo, Zeaphos, Attrex, 6-Chloro-N-ethyl-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine, Atraflow plus, s-Triazine, 2-chloro-4-(ethylamino)-6-(isopropylamino)-, UNII-QJA9M5H4IM, G 30027, Radazin T, Atrazine 4l, Griffex 4l, Atrazine 80W, Azinotox 500, CCRIS 1025, HSDB 413, 1-Chloro-3-ethylamino-5-isopropylamino-s-triazine, 2-Chloro-4-(2-propylamino)-6-ethylamino-s-triazine, AI3-28244, s-Triazine, 2-chloro-4-ethylamino-6-isopropylamino-, 2-Aethylamino-4-chlor-6-isopropylamino-1,3,5-triazin, MXWJVTOOROXGIU-UHFFFAOYSA-N, 1-Chloro-3-ethylamino-5-isopropylamino-2,4,6-triazine, 6-chloro-N-ethyl-N'-isopropyl-1,3,5-triazine-2,4-diamine, EINECS 217-617-8, 2-Chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, 6-Chloro-N2-ethyl-N4-isopropyl-1,3,5-triazine-2,4-diamine, QJA9M5H4IM, 2-CHLORO-4-ISOPROPYLAMINO-6-ETHYLAMINO -1,3,5-TRIAZINE, EPA Pesticide Chemical Code 080803, NSC 163046, C8H14ClN5, BRN 0612020, 2-Chloro-4-(ethylamino)-6-(isopropylamino)-s-triazine, CHEBI:15930, 2-Aethylamino-4-chlor-6-isopropylamino-1,3,5-triazin [German], 2-Aethylamino-4-isopropylamino-6-chlor-1,3,5-triazin [German], 6-chloro-N-ethyl-N'-(propan-2-yl)-1,3,5-triazine-2,4-diamine, 1,3,5-Triazine-2,4-diamine, 6-chloro-N2-ethyl-N4-(1-methylethyl)-, 2-Aethylamino-4-isopropylamino-6-chlor-1,3,5-triazin, 1-Chloro-3-(ethylamino)-5-(isopropylamino)-s-triazine, 2-Chloro-4-(2-propylamino)-6-(ethylamino)-s-triazine, 6-Chloro-4-(ethylamino)-2-(isopropylamino)-s-triazine, 2-CHLORO-4-ETHYLAMINO-6-ISOPROPYLAMINO-sym-TRIAZINE, 2-CHLORO-4-ISOPROPYLAMINO-6-ETHYLAMINO-1,3,5-TRIAZINE, 102029-43-6, DSSTox_CID_112, 1,3,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1-methylethyl)- (9CI), DSSTox_RID_75374, DSSTox_GSID_20112, Atrazine, analytical standard, 2-chloro-6-ethylamino-4-isopropylamino-1,3,5-triazine, 1-Chloro-3-(ethylamino)-5-(isopropylamino)-2,4,6-triazine, 6-Chloro-N4-ethyl-N2-isopropyl-1,3,5-triazine-2,4-diamine, 6-chloro-4-N-ethyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine, SMR000255992, CAS-1912-24-9, Crisazina, Cyazine, Zeapho, Fermco atrazine, [4-chloro-6-(ethylamino)(1,3,5-triazin-2-yl)](methylethyl)amine, Primitol A, Oleogesaprim 200, Gesaprim 500, Spectrum_001821, SpecPlus_000422, Spectrum2_001880, Spectrum3_000821, Spectrum4_000661, Spectrum5_001954, bmse000835, EC 217-617-8, AC1L1D9U, Oprea1_839865, SCHEMBL36936, BSPBio_002341, KBioGR_001061, KBioSS_002326, SPECTRUM330029, MLS000389718, MLS001055469, BIDD:ER0403, CHEMBL15063, DivK1c_006518, 2-Chloro-4-(ethylamino)-6-(isopropylamino)triazine, SPBio_001760, AC1Q31I9, DTXSID9020112, CTK6F2241, KBio1_001462, KBio2_002323, KBio2_004891, KBio2_007459, KBio3_001841, MolPort-000-476-263, HMS2541C15, HMS3604N05, BCP12774, ZINC3078958, Atrazine 100 microg/mL in Toluene, Tox21_201986, Tox21_301021, ANW-42206, CCG-39357, LS-962, MFCD00041810, NSC163046, SBB003393, STL115099, Atrazine 10 microg/mL in Cyclohexane, AKOS001023901, AKOS003625798, AM84660, Atrazine 10 microg/mL in Acetonitrile, DB07392, MCULE-1965771911, NSC-163046, Atrazine 100 microg/mL in Acetonitrile, NCGC00090784-01, NCGC00090784-02, NCGC00090784-03, NCGC00090784-04, NCGC00090784-05, NCGC00090784-06, NCGC00090784-07, NCGC00090784-08, NCGC00090784-09, NCGC00090784-10, NCGC00254923-01, NCGC00259535-01, AC-12050, AC-12056, AN-25532, AS-13785, S334, SC-79745, WLN: T6N CN ENJ BMY1&1 DM2 FG, KB-169692, KB-169693, TR-036022, Atrazine, PESTANAL(R), analytical standard, FT-0602866, FT-0662335, ST50112804, C06551, J10310, 33270-EP2274983A1, 33270-EP2305655A2, 33270-EP2305658A1, 33270-EP2305662A1, 33270-EP2311815A1, 33270-EP2371823A1, 029A436, A813475, AG-668/02857017, 2-Aethylamino-4-chlor-6-isopropylamino-1,5-triazin, 2-chloro-4-ethyl-amino-6-isopropylamino-s-triazine, I14-1570, J-012357, Atrazine, certified reference material, TraceCERT(R), BRD-K45535217-001-02-2, 1-Chloro-3-(ethylamino)-5-(isopropylamino)-2,6-triazine, 2-Chloro-4-(ethylamino)-6-(isopropylamino)-1,5-triazine, Atrazine solution 1000 mug/mL in methyl tert-butyl ether, 1,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1-methylethyl)-, 2-Chloro-4-(ethylamino)-6-[(prop-2-yl)amino]-1,3,5-triazine, 6-chloranyl-N4-ethyl-N2-propan-2-yl-1,3,5-triazine-2,4-diamine, 6-Chloro-N-ethyl-N'-(1-methylethyl)-1,5-triazine-2,4-diamine, 6-chloro-N2-ethyl-N4-(propan-2-yl)-1,3,5-triazine-2,4-diamine, 6-Chloro-N4-ethyl-N2-(prop-2-yl)-1,3,5-triazine-2,4-diamine, 6-chloro-N4-ethyl-N2-propan-2-yl-1,3,5-triazine-2,4-diamine, N-[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]-N-isopropylamine, N2-ETHYL-N4-ISOPROPYL-6-CHLORO-1,3,5-TRIAZINE-2,4-DIAMINE, 6-chloro-4-N-ethyl-2-N-(propan-2-yl)-1,2,3,4-tetrahydro-1,3,5-triazine-2,4-diimine, Atrazine solution, 100 mug/mL in methanol, PESTANAL(R), analytical standard, Atrazine solution, certified reference material, 1000 mug/mL in methyl tert-butyl ether, 11121-31-6, 12040-45-8, 12797-72-7, 39400-72-1, 69771-31-9, 93616-39-8

ID: 1441

InChIKey: MXXWOMGUGJBKIW-YPCIICBESA-N
SMILES: C1CCN(CC1)C(=O)/C=C/C=C/C2=CC3=C(C=C2)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 638024
synonyms found at PubChem are:
piperine, 94-62-2, 1-Piperoylpiperidine, Piperin, Bioperine, Piperoylpiperidine, (E,E)-1-piperoylpiperidine, N-[(E,E)-Piperoyl]piperidine, 7780-20-3, Piperidine, 1-piperoyl-, (E,E)-, UNII-U71XL721QK, FEMA No. 2909, CCRIS 5572, Piperine (aliphatic), 1-Piperoylpiperidine, (E,E)-, C17H19NO3, EINECS 202-348-0, NSC 21727, 1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoyl]piperidine, N-(E,E)-piperoyl-piperidine, CHEMBL43185, U71XL721QK, CHEBI:28821, MXXWOMGUGJBKIW-YPCIICBESA-N, NSC21727, piperidine, 1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, 1,3-Benzodioxol-5-yl-1-oxo-2,4-pentadienyl-piperine, ST079380, DSSTox_CID_1805, (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one, 1-(5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)piperidine, (E,E)-, 1-[(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine, P-6920, Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, (E,E)-, Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-, (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, DSSTox_RID_76339, DSSTox_GSID_21805, 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine, (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one, Piperidine, 1-((2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, NSC 242267, Piperine [USP], SMR000112278, AI3-01439, SR-01000638580, Piperidine, 1-piperoyl-, piperine, (E,E)-isomer, 1-(5-(3,4-Methylenedioxyphenyl)-1-oxo-2,4-pentadienyl)piperidine, (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine, (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, (2E,4E)-5-(2H-benzo[3,4-d]1,3-dioxolen-5-yl)-1-piperidylpenta-2,4-dien-1-one, CAS-94-62-2, Piperine,(S), 1-Piperylpiperidine, Prestwick_398, Black pepper extract, 1-Piperoyl-piperidine, AC1LCVHI, Piperine, >=97%, PubChem15874, Piperidine, (E,E)-, AC1Q5COB, Prestwick2_000474, Prestwick3_000474, Spectrum5_001507, AI 3-01439, D0H7PW, 1-PIPERONYLPIPERIDINE, Piperine, >=97%, FG, SCHEMBL94058, SCHEMBL94059, BSPBio_000608, BSPBio_002515, Piperine, analytical standard, MLS002153830, MLS002473213, BIDD:ER0675, SPECTRUM1500873, Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, BIDF1038, BPBio1_000670, GTPL2489, N-EE-PIPEROYL-PIPERIDINE, 5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, DTXSID3021805, Piperidine, 1-(5-(3,4-methylenedioxyphenyl)-1-oxo-2,4-pentadienyl)-, Piperine (1-Piperoylpiperidine), CHEBI:93043, FEMA 2909, HMS502P16, 2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)-, MolPort-001-759-210, MolPort-009-671-559, HMS1569O10, HMS1921M12, HMS2092M22, HMS2096O10, HMS2270M18, Pharmakon1600-01500873, BCP18901, HY-N0144, ZINC1529772, ZX-AT010800, Tox21_201990, Tox21_302746, 1-PIPEROYL-(E,E)-PIPERIDINE, BBL027541, BDBM50148573, BN0821, CCG-39991, MFCD00005839, NSC-21727, NSC757803, OR1175, s2344, SBB037863, STL377909, AKOS003369047, CS-6155, DB12582, LS-2194, MCULE-2161604269, NSC-757803, RL04994, SDCCGMLS-0066693.P001, IDI1_000954, (piperidin-1-yl)penta-2,4-dien-1-one, NCGC00094872-01, NCGC00094872-02, NCGC00094872-03, NCGC00094872-04, NCGC00094872-05, NCGC00094872-06, NCGC00094872-09, NCGC00256392-01, NCGC00259539-01, AC-11746, AN-24296, AS-17442, SC-46661, SBI-0051621.P002, N1674, P0460, A-7809, C03882, AB00052185_08, AG-205/01792022, (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-1-, SR-01000638580-1, SR-01000638580-2, SR-01000638580-5, SR-01000638580-6, BRD-K59522102-001-08-8, 1,3-Benzodioxol-5-yl-1-oxo-2,4-pentadienyl-piperidine, Piperine, European Pharmacopoeia (EP) Reference Standard, 1-[5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine, 4-(1,3-Benzodioxole-5-yl)-1,3-butenylpiperidino ketone, (E,E)-5-(3,4-Methylenedioxyphenyl)-2,4-pentadienoylpiperidide, 5-(3,4-methylenedioxyphenyl)-2,4-pentadienoyl-2-piperidine, Piperine, United States Pharmacopeia (USP) Reference Standard, Piperidine,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-, (E,E) 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine, 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine #, (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one, 5-?(1,?3-?benzodioxol-?5-?yl)?-?1-?(1-?piperidinyl)?-2,?4-?Pentadien-?1-?one, Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, (E,E)- (9CI), 147030-08-8, InChI=1/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3

ID: 1442

InChIKey: MYUBYOVCLMEAOH-UHFFFAOYSA-N
SMILES: C1CN=C(N1)C2COC3=CC=CC=C3O2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 154494
synonyms found at PubChem are:
IDAZOXAN HYDROCHLORIDE, 79944-56-2, Idazoxan HCl, RX 781094, MLS000069708, SMR000058458, SR-01000000206, Opera_ID_847, AC1L4CEL, D01ZNH, MLS001148081, SCHEMBL707367, CHEMBL543467, CTK8G0263, MolPort-003-941-824, MYUBYOVCLMEAOH-UHFFFAOYSA-N, (+/-)-Idazoxan Monohydrochloride, HMS1570J14, Pharmakon1600-01506073, Tox21_500652, BN0267, MFCD00069293, NSC759867, AKOS024458652, CCG-214002, LP00652, NSC-759867, RX 781094A, 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride, 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-,monohydrochloride, NCGC00094015-01, NCGC00094015-02, NCGC00261337-01, 90755-83-2, LS-78425, EU-0100652, FT-0630876, 79944-56-2 (HCl),, I 6138, C-14444, SR-01000000206-2, SR-01000000206-4, SR-01000000206-6, SR-01000000206-7, 2-(1,4-benzodioxan-2-yl)-2-imidazolinehydrochloride, (+/-)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride, 2-(1,4-BENZODIOXAN-2-YL)-2-IMIDAZOLINE HYDROCHLORIDE, ( inverted exclamation markA)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride, 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole Hydrochloride, 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole hydrochloride, 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride, AC1LCWAI, AKOS026749795, 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole; hydron; chloride

ID: 1443

InChIKey: MYWNCIQWMVRZCY-UHFFFAOYSA-N
SMILES: C1=COC(=C1)C2=NOC(=C2)CO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 15458986
synonyms found at PubChem are:
27473-55-8, 3-(2-Furanyl)-5-isoxazolemethanol, AKOS022358200, (3-(furan-2-yl)isoxazol-5-yl)methanol, 5-Isoxazolemethanol, 3-(2-furanyl)- (9CI)

ID: 1444

InChIKey: MZDGQNFFUITEAB-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3OC)OC)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3336566
synonyms found at PubChem are:
SPBio_001931, DIOONFLAVONE, Spectrum2_001926, AC1MO13A, Amentoflavone hexamethyl ether, MolPort-002-834-823, ZINC8439387, CCG-38493, MCULE-5326851418, 8-[5-(5,7-dimethoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one

ID: 1445

InChIKey: MZOPWQKISXCCTP-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5614
synonyms found at PubChem are:
tyrphostin A9, Malonoben, 10537-47-0, Tyrphostin 9, NSC 242557, Malonoben [ANSI], 2-(3,5-Di-tert-butyl-4-hydroxybenzylidene)malononitrile, GCP 5126, ENT 27910, Caswell No. 291AA, UNII-87TE8MRS65, Gulf S-15126, SF 6847, Tyrphostin 9/AG-9, (3,5-Di-t-butyl-4-hydroxybenzylidene)malononitrile, AG 17, S-15126, EPA Pesticide Chemical Code 537200, 3,5-di-t-Butyl-4-hydroxy-benzylidenemalononitrile, BRN 2700764, RG-50872, AI3-27910, MLS002702095, 87TE8MRS65, CHEBI:82168, GCP5126, NSC242557, RG 50872, 2-[(3,5-di-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile, 2-((3,5-Bis(1,1-dimethyl)-4-hydroxyphenyl)methylene)propanedinitrile, 2-((3,5-bis(1,1-Dimethylethyl)-4-hydroxyphenyl)methylene)propanedinitrile, Propanedinitrile, ((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-, Propanedinitrile, 2-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-, 3,5-Di-tert-butyl-4-hydroxybenzilidenemalononitrile, Tyrphostin 9 (RG-50872, Malonaben, SF 6847), alpha-Cyano-(3,5-di-t-butyl-4-hydroxy)cinnamonitrile, (3,5-Di-tert-butyl-4-hydroxy-benzylidene)malononitrile, (3,5-di-tert-butyl-4-hydroxybenzylidene)propanedinitrile, MALONONITRILE, 3,5-DI-tert-BUTYL-4-HYDROXYBENZYLIDENE-, 2-[(3,5-ditert-butyl-4-hydroxy-phenyl)methylene]propanedinitrile, 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile, [[3,5-bis(1,1-Dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile, Propanedinitrile,2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, (6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxam, SMR001230759, Malonoben [ANSI:ISO], Malonaben, propanedinitrile, 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, Tyrphostin AG 17, Tyrphostin A9, solid, Lopac-T-182, AC1L1KQQ, BiomolKI_000020, BiomolKI2_000009, AC1Q4PY2, Neuro_000115, CBiol_001719, Lopac0_001254, Oprea1_168738, BMK1-C8, BSPBio_001200, KBioGR_000540, KBioSS_000540, 4-10-00-02178 (Beilstein Handbook Reference), MLS002153354, CHEMBL78150, SCHEMBL120440, Tyrphostin 9 (SF 6847), AG17, BDBM4325, ZINC5256, DTXSID1042106, CTK8G3674, KBio2_000540, KBio2_003108, KBio2_005676, KBio3_000979, KBio3_000980, KS-00000XPI, MolPort-002-142-161, MZOPWQKISXCCTP-UHFFFAOYSA-N, Bio1_000005, Bio1_000494, Bio1_000983, Bio2_000440, Bio2_000920, HMS1362L21, HMS1792L21, HMS1990L21, HMS2232D08, HMS3263L10, HMS3371F08, HMS3403L21, HMS3651J06, BCP06486, Malononitrile, (3,5-di-tert-butyl-4-hydroxybenzylidene)- (8CI), Tox21_501254, HSCI1_000185, MFCD00209853, s2895, STL406446, Tyrphostin 9 pound AG-17 pound(c), AKOS024319213, AN-5049, CCG-100624, CS-1033, LP01254, MCULE-2226202492, NSC-242557, QC-1143, RL00244, SF-6847, IDI1_002195, benzylidenemalononitrile (BMN) deriv. 9, NCGC00015992-01, NCGC00015992-02, NCGC00015992-03, NCGC00015992-04, NCGC00015992-05, NCGC00015992-06, NCGC00015992-07, NCGC00094494-01, NCGC00094494-02, NCGC00094494-03, NCGC00094494-04, NCGC00094494-05, NCGC00261939-01, HY-15511, LS-88908, NCI60_001943, ZB000608, AB0035909, KB-309139, EU-0101254, T-182, Y0356, C19039, S-7671, 2,6-Di-tert-butyl-4-(2,2-dicyanovinyl)phenol, SR-01000075534, J-001407, J-524054, Malononitrile,5-di-tert-butyl-4-hydroxybenzylidene-, SR-01000075534-1, 3,5-di-tert-butyl-4-hydroxybenzylidene-malononitrile, BRD-K40255344-001-04-4, BRD-K40255344-001-05-1, (3,5-di-tert-butyl-4-hydroxybenzylidene)-Malononitrile, 2-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-malononitrile, Malononitrile, (3,5-di-tert-butyl-4-hydroxybenzylidene)-, 2-[[3,1-dimethyl)-4-hydroxyphenyl]methylene]propanedinitrile, 2-[[3,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile, [[3,5-bis(1,1-Dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile, Propanedinitrile,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, [[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile, 9CI, 51601-81-1, 68072-88-8

ID: 1446

InChIKey: NAEUGRPISCANHO-BTJKTKAUSA-N
SMILES: CC1=CC=CC(=C1)C(=O)NCN2CCN(CC2)C3=CC=CC=C3C#N.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11957665
synonyms found at PubChem are:
PD 168077 maleate, PD 168,077 maleate, 190383-31-4, PD168077 Maleate, 630117-19-0, PD 168,077 maleate salt, N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide maleate, SR-01000075374, N-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-3-methylbenzamide maleate salt, EU-0100969, CHEMBL1256874, DTXSID1042601, MolPort-003-959-196, PD 168 077 MALEATE, HMS3263A19, Tox21_500969, BN0412, MFCD01321067, PD 168,077 maleate salt, powder, AKOS024256763, CCG-222273, LP00969, NCGC00094269-01, NCGC00261654-01, AK201332, AB0064922, KB-125350, P-233, J-012293, SR-01000075374-1, SR-01000075374-3, N-(Methyl-4-(2-cyanophenyl)piperazinyl-3-methylbenzamide maleate, N-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-3-methyl-benzamide maleate, N-{[4-(2-cyanophenyl)piperazin-1-yl]methyl}-3-methylbenzamide (2Z)-but-2-enedioate

ID: 1447

InChIKey: NBQNWMBBSKPBAY-UHFFFAOYSA-N
SMILES: CC(=O)N(CC(CN(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)C)O)C2=C(C(=C(C(=C2I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3724
synonyms found at PubChem are:
iodixanol, 92339-11-2, Visipaque, Iodixanolum, Indixanol, Visipaque 270, Visipaque 320, Iodixanolum [Latin], UNII-HW8W27HTXX, CCRIS 7567, HW8W27HTXX, CHEBI:31705, 2-5410-3A, 5,5'-((2-Hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide), DSSTox_CID_25523, DSSTox_RID_80929, DSSTox_GSID_45523, OptiPrep, 1,3-Benzenedicarboxamide, 5,5'-((2-hydroxy-1,3-propanediyl)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-, 5-[acetyl-[3-[N-acetyl-3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodoanilino]-2-hydroxypropyl]amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, SR-01000872678, Acupaque, Iodixanol [USAN:BAN:INN], HSDB 8076, Iodixanol [USAN:USP:INN:BAN], Visipaque (TN), NCGC00016958-01, CAS-92339-11-2, AC1L1GKH, Prestwick0_000848, Prestwick1_000848, Prestwick2_000848, Prestwick3_000848, D0Y4YG, EC 618-837-0, Iodixanol (JAN/USP/INN), SCHEMBL21546, BSPBio_000835, SPBio_002756, BPBio1_000919, CHEMBL1200507, DTXSID2045523, CTK8G0329, NBQNWMBBSKPBAY-UHFFFAOYSA-N, HMS1570J17, HMS2097J17, HMS3714J17, Pharmakon1600-01503835, BCP11111, Tox21_110711, GP8799, NSC760069, AKOS015895607, Tox21_110711_1, AC-7610, AN-8826, CCG-213207, DB01249, DU-6807, NSC-760069, NCGC00179408-01, NCGC00179408-03, 5-(Acetyl-(3-(acetyl-(3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodophenyl)amino)-2- hydroxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide; 5,5'-((2-hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6- triiodoisophthalamide);, CC-29560, LS-29753, 2-541O-3A, AB00513936, FT-0627254, FT-0645028, D01474, AB00513936_02, 339I112, A844203, C-23647, SR-01000872678-1, SR-01000872678-2, BRD-A08660406-001-01-8, OptiPrep(TM) Density Gradient Medium, used for cell and subcellular organelle isolation, 1,3-Benzenedicarboxamide, 5,5'-[(2-hydroxy-1,3- propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3- dihydroxypropyl)-2,4,6-triiodo-, 5,5'-(2-hydroxypropane-1,3-diyl)bis(acetylazanediyl)bis(N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide), 5,5'-[(2-hydroxypropane-1,3-diyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide], 5-[[3-[[3,5-bis[2,3-bis(oxidanyl)propylcarbamoyl]-2,4,6-tris(iodanyl)phenyl]-ethanoyl-amino]-2-oxidanyl-propyl]-ethanoyl-amino]-N1,N3-bis[2,3-bis(oxidanyl)propyl]-2,4,6-tris(iodanyl)benzene-1,3-dicarboxamide, 5-[acetyl-[3-[N-acetyl-3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodo-anilino]-2-hydroxy-propyl]amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-benzene-1,3-dicarboxamide, 5-[acetyl-[3-[N-acetyl-3,5-bis[(2,3-dihydroxypropylamino)-oxomethyl]-2,4,6-triiodoanilino]-2-hydroxypropyl]amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, 5-{N-[3-(N-{3,5-bis[(2,3-dihydroxypropyl)carbamoyl]-2,4,6-triiodophenyl}acetamido)-2-hydroxypropyl]acetamido}-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide

ID: 1448

InChIKey: NBYATBIMYLFITE-UHFFFAOYSA-N
SMILES: CCCCCCCCCC[Si](C)(C)CCC(=O)NC(CC1=CC=C(C=C1)C)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 122215
synonyms found at PubChem are:
Sandoz 58-035, Compound-58-035, 78934-83-5, SAN 58035, San 58-035, CHEMBL40998, 3-(Decyldimethylsilyl)-N-(2-(4-methylphenyl)-1-phenylethyl)propanamide, SA-58035, SA 58-035, 3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide, Propanamide, 3-(decyldimethylsilyl)-N-(2-(4-methylphenyl)-1-phenylethyl)-, Sandoz 58035, C30H47NOSi, SAN-58035, Sandoz58-35, AC1Q2VYK, AC1L3U77, SCHEMBL4430655, CTK8G3050, HMS3260K15, KS-000018AA, Tox21_500057, BDBM50034738, MFCD00161339, CCG-204152, LP00057, NCGC00015980-02, NCGC00015980-03, NCGC00015980-04, NCGC00093571-01, NCGC00093571-02, NCGC00260742-01, LS-177436, EU-0100057, Sandoz 58-035, >98% (HPLC), powder, S 9318, S-58035, SR-01000075677, SR-01000075677-1, 3-(Decyl-dimethyl-silanyl)-N-(1-phenyl-2-p-tolyl-ethyl)-propionamide, 3-(decyl-dimethylsilyl)-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide, 3-[decyl(dimethyl)silyl]-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide

ID: 1449

InChIKey: NCCWCZLEACWJIN-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1C(=O)OC)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 76658
synonyms found at PubChem are:
Methyl orsellinate, 3187-58-4, Methyl 2,4-dihydroxy-6-methylbenzoate, Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester, Methyl 4,6-dihydroxy-2-methylbenzoate, Methyl 2,4-dihydroxy-6-methyl benzoate, CHEMBL454431, CHEBI:67898, NCCWCZLEACWJIN-UHFFFAOYSA-N, Benzoic acid,2,4-dihydroxy-6-methyl-, methyl ester, methylorsellinate, Methyl o-orsellinate, Orsellinic acid methyl, AC1L2RDY, Spectrum2_001751, AC1Q5Z2J, orsellinic acid methyl ester, .beta.-Resorcylic acid, 6-methyl-, methyl ester, SPECTRUM210925, MLS000728678, SCHEMBL370816, SPBio_001882, Orsellinic acid monomethyl ester, DTXSID2062901, CTK4G7872, HMS2267N11, ZINC391406, ANW-46738, BDBM50294528, CCG-39451, FCH840193, Methyl2,4-dihydroxy-6-methylbenzoate, AKOS000349113, ACM3187584, methyl 2,4-dihydroxy-6-methyl-benzoate, NCGC00095797-01, 4CN-2131, AJ-21085, SMR000470886, AX8222683, KB-255280, TC-135483, BB 0218022, ST24025149, W1988, 2,4-Dihydroxy-6-methylbenzoic acid methyl ester, SR-01000761473, SR-01000761473-2, BRD-K12202814-001-05-8

ID: 1450

InChIKey: NCEGJIHRQBRVJQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)CP(=O)(O)O)C2=CC(=CC=C2)CC(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4779
synonyms found at PubChem are:
PMBA, Phenylbenzene-omega-phosphono-alpha-amino acid, 3-[2'-Phosphonomethyl[1,1'-biphenyl]-3-yl]alanine, 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid, 2-amino-3-{3-[2-(phosphonomethyl)phenyl]phenyl}propanoic acid, AC1L1IXQ, D0AD1L, Lopac0_001008, GTPL4289, CHEMBL1416659, HMS3263I17, Tox21_501008, CCG-205088, LP01008, NCGC00015789-02, NCGC00015789-03, NCGC00015789-04, NCGC00094301-01, NCGC00094301-02, NCGC00261693-01, EU-0101008, P-204, SR-01000075469, SR-01000075469-1, alpha-Amino-2'-(phosphonomethyl)-1,1'-biphenyl-3-propanoic acid

ID: 1451

InChIKey: NCEXCGUAXVAJMI-UHFFFAOYSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)C2=COC3=CC(=C(C(=C3C2=O)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4303569
synonyms found at PubChem are:
IRIGENIN TRIMETHYL ETHER, KBio3_001251, Spectrum_000649, SpecPlus_000111, AC1N7JPE, Spectrum2_000191, Spectrum3_000196, Spectrum4_001513, Spectrum5_000305, BSPBio_001751, KBioGR_002205, KBioSS_001129, SPECTRUM200873, DivK1c_006207, SPBio_000141, CHEMBL1881203, KBio1_001151, KBio2_001129, KBio2_003697, KBio2_006265, CHEBI:113560, CCG-38397, SDCCGMLS-0066398.P001, NCGC00095494-01, NCGC00095494-02, NCGC00179035-01, SR-05000002643, SR-05000002643-1, BRD-K85880973-001-02-7, BRD-K85880973-001-03-5, 5,6,7-trimethoxy-3-(3,4,5-trimethoxyphenyl)chromen-4-one

ID: 1452

InChIKey: NCGICGYLBXGBGN-UHFFFAOYSA-N
SMILES: C1COCCN1[N+]2=CC(=N)O[N-]2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 9859122
synonyms found at PubChem are:
3-Morpholinosydnonimine hydrochloride, Linsidomine hydrochloride, 16142-27-1, 3-MORPHOLINOSYDNONIMINE, MLS000028691, SIN-1, Hydrochloride, 3-Morpholinosydnonimine (SIN-1), SMR000058925, 3-(4-Morpholinyl)sydnone imine hydrochloride, sin-1, (3-Morpholino-1,2,3-oxadiazol-3-ium-5-yl)amide hydrochloride, 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride, Opera_ID_1704, 3-Morpholinosydnonimine HCl, MLS000860006, SCHEMBL960238, CHEMBL538104, CTK8F5149, NCGICGYLBXGBGN-UHFFFAOYSA-N, 3-(4-Morpholinyl)Sydnonimine HCl, 3-Morpholinosydnoimine hydrochloride, Tox21_500247, Tox21_500854, CM-644, MFCD00214332, 3-morpholino-sydnonimine hydrochloride, 3-morpholinosydnonimine hydro-chloride, AKOS022181148, AKOS025213271, CCG-221551, CCG-222158, LP00247, LP00854, MCULE-8390964760, NCGC00094181-01, NCGC00260932-01, NCGC00261539-01, SMR000326865, MLS-0003225.P022, EU-0100854, FT-0616203, M-184, J-009828, J-019356, 5-imino-3-morpholino-5H-1,2,3-oxadiazol-3-ium-2-ide hydrochloride, 3-(Morpholin-4-yl)sydnonimine Hydrochloride (Linsidomine Hydrochloride), 3-Morpholinosydnonimine hydrochloride, (consistent with structure, NMR), 5-imino-3-(morpholin-4-yl)-2H-1,2,3$l^{5}-oxadiazol-3-ylium-2-ide hydrochloride

ID: 1453

InChIKey: NCMZQTLCXHGLOK-ZKHIMWLXSA-N
SMILES: CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 14709
synonyms found at PubChem are:
Dehydroepiandrosterone acetate, 853-23-6, Prasterone acetate, Dehydroisoandrosterone 3-acetate, Dehydroisoandrosterone acetate, Androstenolone acetate, trans-Dehydroandrosterone acetate, 3beta-Acetoxy-5-androstene-17-one, Dehydroisoandosterone 3-acetate, CCRIS 7926, Dehydroepiandrosterone 3-acetate, UNII-45751H45MY, 3-beta-Acetoxydehydroepiandrosterone, SKF 2847, EINECS 212-714-1, 5-Androsten-3beta-ol-7-one acetate, 17-Oxoandrost-5-en-3beta-yl acetate, delta5-Dehydroepiandrosterone 3-acetate, Dehydroepiandrost-5-en-17-one 3-acetate, 3beta-Hydroxy-5-androsten-17-one acetate, 3beta-Hydroxyandrost-5-en-17-one acetate, 3beta-Hydroxy-5-androstene-17-one acetate, 3-beta-Hydroxyandrost-5-en-17-one acetate, 3beta-Hydroxyandrost-5-en-17-one 3-acetate, NCMZQTLCXHGLOK-ZKHIMWLXSA-N, 3beta-acetoxyandrost-5-en-17-one, Androst-5-en-17-one, 3-(acetyloxy)-, (3-beta)-, 45751H45MY, [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate, (3beta)-17-oxoandrost-5-en-3-yl acetate, DSSTox_CID_380, DSSTox_RID_75554, Androst-5-en-17-one, 3-(acetyloxy)-, (3b)-, Androst-5-en-17-one, 3-beta-hydroxy-, acetate, DSSTox_GSID_20380, 17-Oxoandrost-5-en-3-yl acetate #, NCGC00016544-01, (3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate, CAS-853-23-6, Prestwick0_000937, Prestwick1_000937, Prestwick2_000937, Prestwick3_000937, Dehydroepiandrosteroneacetate, BSPBio_000874, MLS002154068, SCHEMBL298142, SPBio_003043, OOEaINCaOiEthUcThornI feminine, AC1L24E6, BPBio1_000962, CHEMBL1480686, DTXSID3020380, CHEBI:135410, MolPort-002-506-956, 3betaacetoxy-5-androstene-17-one, HMS1570L16, HMS2097L16, HMS2230I06, HMS3714L16, 3beta-acetoxy-5-androsten-17-one, HY-B1405, ZINC3881408, 3beta-acetoxy-androst-5-en-17-one, Tox21_110485, Tox21_200963, 3beta-acetoxy-5-androstene -17-one, AKOS015895423, CCG-220937, CHM0029112, CS-6082, Dehydroisoandrosterone 3-acetate, 97%, EBD2197393, LS-7297, MCULE-4605464077, NCGC00179388-01, NCGC00179388-02, NCGC00258516-01, AK307717, AN-47791, AS-20015, SMR001233383, (3?)-17-Oxoandrost-5-en-3-yl acetate, TL8005578, 5-Androsten-3.beta.-ol-17-one, 3-acetate, AB00171449, D0045, Z3653, A-7919, Androst-5-en-17-one,3-(acetyloxy)-, (3b)-, 853D236, Q-200934, BRD-K96527333-001-03-4, 3-|A-oC>>u-E yenNoEthUcThorn-5-I(c)-17-I feminine-3- xEao yen, (1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-oxotetracyclo[8.7.0.02,7.011,15]heptadec-7-en-5-yl acetate

ID: 1454

InChIKey: NDAUXUAQIAJITI-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2083
synonyms found at PubChem are:
Salbutamol, albuterol, 18559-94-9, Proventil, Sultanol, Volmax, Broncovaleas, Aerolin, dl-Salbutamol, dl-Albuterol, Ventolin Inhaler, Ventolin, Proventil HFA, Asthalin, Buventol, Cobutolin, Salbulin, Salbuvent, Saventol, Ventoline, Asmaven, Salamol, Spreor, Asmol, Sultanol N, Proventil Inhaler, Ventolin Rotacaps, Novosalmol, Salbuhexal, Salbutalan, Salbutamolum, Servitamol, Ventiloboi, Ventodisks, Almotex, Anebron, Asmadil, Asmanil, Asmasal, Asmatol, Asmidon, Bronter, Bugonol, Butamol, Butohaler, Butotal, Butovent, Dilatamol, Farcolin, Gerivent, Grafalin, Libretin, Medolin, Parasma, Pneumolat, Respolin, Sabutal, Salbetol, Salbron, Salbupur, Salbusian, Salbutan, Salbutol, Salbuven, Sallbupp, Salmaplon, Salomol, Salvent, Suprasma, Theosal, Tobybron, Vencronyl, Ventamol, Ventilan, Zaperin, Bumol, Mozal, Respax, Suxar, Alti-Salbutamol, Broncho-Spray, Salbu-Fatol, Buto-Asma, Asmol Uni-Dose, Salbu-BASF, Salbutamol Sulphate, Volare easi-breathe, Arubendol-Salbutamol, Airomir, Volare albuterol HFA, Ventalin inhaler, R,S-Albuterol, (+-)-Salbutamol, (+-)-Albuterol, Solbutamol, Salbutamolum [INN-Latin], Albuterol [USAN], 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol, Ecovent, Rotahaler, Sabutamol, Salbutamol sulfate, Salbutard, Salbutine, Cetsim, Volma, AH 3365, ProAir, (l)-albuterol, 4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol, racemic-Salbutamol, Albuterol Sulphate, Proventil (TN), Albuterol (USP), ALBUTEROL SULFATE, AccuNeb, Salbutamol Free Base, 2-(tert-Butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol, HSDB 7206, EINECS 242-424-0, 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-alpha1,alpha3-diol, alpha'-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol, alpha-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha'-diol, BRN 2213614, ALBUTEROL (+/-), 4-Hydroxy-3-hydroxymethyl-alpha-((tert-butylamino)methyl)benzyl alcohol, Combivent, DL-N-tert-Butyl-2-(4-hydroxy-3-hydroxymethylphenyl)-2-hydroxyethylamine, alpha(sup 1)-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol, CHEBI:2549, NDAUXUAQIAJITI-UHFFFAOYSA-N, Salbutamol-d9, 35763-26-9, NCGC00015955-09, Proair HFA, Ventolin (TN), 2-t-Butylamino-1-(4-hydroxy-3-hydroxy-3-hydroxymethyl)phenylethanol, DSSTox_CID_1255, m-Xylene-alpha,alpha'-diol, alpha-((tert-butylamino)methyl)-4-hydroxy-, 1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, 4-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol, S 8260, (+-)-alpha(sup 1)-(((1,1-Dimethylethyl)amino)methyl)-4-hydroxy-1,3-benzenedimethanol, DSSTox_RID_76042, DSSTox_GSID_21255, Q-201695, Q-201696, Vospire, Eolene, 4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol, 4-{2-[(tert-butyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol, (alpha1-((tert-butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha-diol), m-Xylene-alpha,alpha'-diol, alpha'-((tert-butylamino)methyl)-4-hydroxy-, 1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, 1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, (+-)-, SCH-13949W, SR-01000075161, Albuterol [USAN:USP], sabumol, Levosalbutamol Hydrochloride, racemic salbutamol, Salamol EB, Asthalin (TN), Prestwick_665, Aerolin (TN), CAS-18559-94-9, alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha'-diol, Salbutamol,(+/-), Venetlin (Salt/Mix), ProAi (TN), Salbutamol (Albuterol), Spectrum_000200, Salbutamol [INN:BAN], AC1L1CVO, Prestwick0_000198, Prestwick1_000198, Prestwick2_000198, Prestwick3_000198, Spectrum2_001350, Spectrum4_000887, Spectrum5_001059, CHEMBL714, D0K5CB, EC 242-424-0, AC1Q1MO0, SCHEMBL4913, Lopac0_001090, Lopac0_001098, BSPBio_000155, GTPL558, KBioGR_001294, KBioSS_000680, Salbutamol, 99% 250mg, DivK1c_000943, SPECTRUM1500677, SPBio_001539, SPBio_002076, BPBio1_000171, SGCUT00011, DTXSID5021255, SCHEMBL10025126, BCBcMAP01_000116, BDBM25769, CTK8E5622, HMS502P05, KBio1_000943, KBio2_000680, KBio2_003248, KBio2_005816, BIS7017, MolPort-001-838-925, NINDS_000943, ZX-AFC000812, Bio1_000446, Bio1_000935, Bio1_001424, HMS1568H17, HMS1921C04, HMS2089I19, HMS2092I08, HMS2095H17, HMS3712H17, KUC106739N, Pharmakon1600-01500677, BCP28423, HY-B1037, to_000081, Tox21_110266, Tox21_200800, CCG-39288, CS0015, MFCD00148978, NSC757417, PDSP1_000623, PDSP2_000620, SBB066105, AKOS007930174, Tox21_110266_1, AN-7048, API0006973, CS-4556, DB01001, KS-5209, LS-7693, MCULE-4493408325, NSC-757417, 1,3-Benzenedimethanol, .alpha.1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, ACM35763269, IDI1_000943, SMP1_000268, NCGC00015955-04, NCGC00015955-05, NCGC00015955-06, NCGC00015955-07, NCGC00015955-08, NCGC00015955-10, NCGC00015955-11, NCGC00015955-12, NCGC00015955-13, NCGC00015955-14, NCGC00015955-16, NCGC00024698-02, NCGC00024698-03, NCGC00024698-04, NCGC00024698-05, NCGC00024698-06, NCGC00024698-07, NCGC00258354-01, AC-10286, AN-18804, CC-23825, KSC-11-222-1, LS-29861, SC-22638, SC-93513, ST024764, ST075204, ST077150, SBI-0051060.P005, AB0011383, AB1006817, AX8136202, TR-008568, AB00052154, EU-0101090, FT-0630453, ST24042831, VU0243312-5, D02147, J10176, K-5595, Salbutamol, VETRANAL(TM), analytical standard, AB00052154-08, AB00052154-09, AB00052154_10, AB00052154_11, 559S949, A812971, C-14301, L000531, I06-0331, Salbutamol free base 100 microg/mL in Acetonitrile, SR-01000075161-3, SR-01000075161-4, SR-01000075161-5, SR-01000075161-8, BRD-A88254928-001-04-6, BRD-A88254928-001-05-3, Salbutamol impurity I (1RS)-2-[(1,1-dimethylethyl), SR-01000075161-11, Salbutamol, European Pharmacopoeia (EP) Reference Standard, Albuterol, United States Pharmacopeia (USP) Reference Standard, 2-(tert-Butylamino)-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanol, 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol #, 4-[2-(tert-butylamino)-1-oxidanyl-ethyl]-2-(hydroxymethyl)phenol, alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha -diol, Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha-diol, 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-.alpha.1,.alpha.3-diol, 4-[(1S)-2-(butylamino)-1-hydroxy-isopropyl]-2-(hydroxymethyl)phenol, 4-Hydroxy-3-hydroxymethyl-.alpha.-((tert-butylamino)methyl)benzyl alcohol, .alpha.'-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-.alpha.,.alpha.'-diol, .alpha.1'-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol, hemisulfate, .alpha.1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-.alpha.,.alpha.'-diol, 1,3-Benzenedimethanol, .alpha.(1)-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, 4-[(1S)-1-hydroxy-2-(propylamino)ethyl]-2-(hydroxymethyl)phenol, oxamethane, m-Xylene-.alpha.,.alpha.'-diol, .alpha.'-((tert-butylamino)methyl)-4-hydroxy-, m-Xylene-.alpha.,.alpha.-diol, .alpha.-1-((tert-butylamino)methyl)-4-hydroxy-

ID: 1455

InChIKey: NDDAHWYSQHTHNT-UHFFFAOYSA-N
SMILES: CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3702
synonyms found at PubChem are:
indapamide, 26807-65-8, Noranat, Veroxil, Tertensif, Arifon, Fludex, Lozol, Indaflex, Bajaten, Indamol, Tandix, Indapamida, Natrilix, Pressurai, Damide, Ipamix, Indapamidum, Metindamide, Cormil, Indapamidum [INN-Latin], Indapamida [INN-Spanish], 1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline, SE-1520, Idapamide, Lozide, Natrix, SE 1520, Apo-Indapamide, Novo-Indapamide, NLozol, Nu-Indapamide, RHC 2555, USV 2555, Indapamide (Lozol), Natrix (TN), Lozol (TN), 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide, Indapamide [USAN:INN:BAN:JAN], Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-, EINECS 248-012-7, S-1520, BRN 1604026, C16H16ClN3O3S, 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide, 3-(Aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide, MLS000028554, CHEBI:5893, 4-CHLORO-N-(2-METHYLINDOLIN-1-YL)-3-SULFAMOYLBENZAMIDE, NDDAHWYSQHTHNT-UHFFFAOYSA-N, 4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide, BENZAMIDE, 4-CHLORO-N-(2-METHYL-1-INDOLINYL)-3-SULFAMOYL-, N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline, NCGC00018172-03, SMR000058829, Indapamide hemihydrate, DSSTox_CID_24633, DSSTox_RID_80366, DSSTox_GSID_44633, N-[4-Chloro-3-sulfamoylbenzamido]-2-methylindoline, 3-(Aminosulfonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)benzamide, Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-l-yl)-, Indapamide (JAN/USP), SR-01000003079, flupamid, indamide, Indapamid, Hypen SR, Natrilix (TN), Indapamide (USP), FLUBEST, IDAMIDE, (+/-)-Indapamide, Indapamide [USAN:USP:INN:BAN:JAN], RAC INDAPAMIDE, Spectrum_000917, Opera_ID_110, AC1L1GIW, Prestwick3_000220, Spectrum2_000980, Spectrum3_000467, Spectrum4_000017, Spectrum5_000866, S1520, CHEMBL406, D0H8FH, Indapamide (JP17/USP), SCHEMBL41303, BSPBio_000239, BSPBio_002174, KBioGR_000393, KBioSS_001397, 5-20-06-00348 (Beilstein Handbook Reference), MLS001148152, MLS002222229, MLS006011900, ARONIS27110, DivK1c_000508, SPECTRUM1500349, SPBio_001019, BPBio1_000263, GTPL7203, DTXSID7044633, BDBM25901, CTK3J2161, HMS501J10, KBio1_000508, KBio2_001397, KBio2_003965, KBio2_006533, KBio3_001394, MolPort-003-666-209, NINDS_000508, HMS1920F19, HMS2090M16, HMS2091N07, HMS2095L21, HMS2231G13, HMS3259C14, HMS3369J20, HMS3655E06, HMS3712L21, Pharmakon1600-01500349, Indapamide 1.0 mg/ml in Methanol, BCP04140, HY-B0259, KS-00000ZZ7, KS-000048LJ, Tox21_110775, Tox21_113182, Tox21_302687, CCG-40198, CI-045, MFCD00079375, NSC757075, s1730, STL257105, STL455045, AKOS015888148, Tox21_110775_1, AB03037, AC-2073, ACN-029813, API0002990, CS-2245, DB00808, KS-5219, MCULE-1549472772, NC00568, NSC-757075, IDI1_000508, NCGC00018172-02, NCGC00018172-04, NCGC00018172-06, NCGC00018172-08, NCGC00018172-09, NCGC00089727-02, NCGC00089727-03, NCGC00256884-01, AN-14323, CC-29500, CPD000058829, LS-26138, SAM002564214, SC-22596, SBI-0051415.P003, AB0012132, AB2000254, RT-000328, TL8002131, AB00052021, FT-0630528, I0730, ST51015024, Arifon;Fludex;Noranat;Veroxil;Tertensif;Lozol, A23574, D00345, J10257, AB00052021-14, AB00052021-15, AB00052021_16, AB00052021_17, 807I658, C-21015, Indapamide, analytical standard, for drug analysis, I01-0369, J-016554, SR-01000003079-2, SR-01000003079-3, BRD-A95869247-001-04-6, BRD-A95869247-001-14-5, N-[4-Chloro-3-sulfamoylbenzamido]-2- methylindoline, Z2786158257, 4-chloro-N-(2-methylindolin-1-yl)-3-sulfamoyl-benzamide, Indapamide, European Pharmacopoeia (EP) Reference Standard, N-[4-CHLORO-3-SULFAMOYLBENZAMIDOL]-2-METHYLINDOLINE, (4-chloro-3-sulfamoylphenyl)-N-(2-methylindolinyl)carboxamide, Indapamide, United States Pharmacopeia (USP) Reference Standard, NLozol, Arifon, Fludex, Noranat, Veroxil, Tertensif, Indapamide, (+/-)-4-CHLORO-N-(2-METHYL-1-INDOLINYL)-3-SULFAMOYLBENZAMIDE, 3-aminosulfonyl-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide, 4-chloro-3-aminosulphonyl-N-(2,3-dihydro2-methyl-1H-indol-1-yl)benzamide, 4-Chloro-N-(2-methyl-2,3-dihydro-indol-1-yl)-3-sulfamoyl-benzamide, Indapamide, Pharmaceutical Secondary Standard; Certified Reference Material, 3-(aminosulphonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1--yl)benzamide, 3-(aminosulphonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)benzamide, 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzenecarboximidic acid, Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)- (9CI), Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-(9CI), 49564-58-1

ID: 1456

InChIKey: NDDRNRRNYOULND-UHFFFAOYSA-N
SMILES: CCN(CCCl)CC1=CC=CC=C1Br.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 38533
synonyms found at PubChem are:
o-Bromo-N-(2-chloroethyl)-N-ethylbenzylamine hydrochloride, BENZYLAMINE, o-BROMO-N-(2-CHLOROETHYL)-N-ETHYL-, HYDROCHLORIDE, DSP 4 hydrochloride, C11H15BrClN.HCl, AC1L1ZZH, 62078-98-2 (Parent), LS-43223, (2-bromophenyl)methyl-(2-chloroethyl)-ethylazanium chloride, DSP-4 hydrochloride, DSP-4, 40616-75-9, N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride, N-Ethyl-N-(2-chloroethyl)-2-bromobenzylamine hydrochloride, EU-0100299, MLS000859958, SCHEMBL2268042, CHEMBL1255650, CTK8F9387, MolPort-003-925-283, MFCD00043241, AKOS024457354, LP00299, ACM40616759, NCGC00093749-01, SMR000326817, B7232, FT-0726819, C 8417, C-48817, SR-01000075248, SR-01000075248-1, N-(2-Bromobenzyl)-2-chloro-N-ethylethanamine hydrochloride, N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride, >=98%, solid

ID: 1457

InChIKey: NDTSRXAMMQDVSW-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CSCC2=NS(=O)(=O)C3=CC(=C(C=C3N2)Cl)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2343
synonyms found at PubChem are:
benzthiazide, Benzothiazide, 91-33-8, Dihydrex, Lemazide, Aquatag, Fovane, Freeuril, Diucen, Edemex, Exosalt, Proaqua, Urese, Exna, Benzotiazida, Benzthiazidum, Diucene, Regulon, Pfizer 1393, Aquapres, Benztiazide, Aquasec, Fouane, Urazide, Hy-drine, Pro-aqua, Aqua-Scrip, Rid-ema, S-Aqua, Benztiazide [DCIT], HyDrine, Benzthiazidum [INN-Latin], Benzotiazida [INN-Spanish], Benzthazide, C15H14ClN3O4S3, P 1393, UNII-1TD8J48L61, Benzthiazide [USAN:INN:BAN], Exna (TN), HSDB 3296, 3-Benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, Benzthiazide (JAN/INN), EINECS 202-061-0, 6-Chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-, 1,1-dioxide, 3-((Benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide, MLS000069562, CHEBI:3047, 1TD8J48L61, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(((phenylmethyl)thio)methyl)-, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[[(phenylmethyl)thio]methyl]-, 1,1-dioxide, 3-((Benzylthio)methyl)-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-((Benzylthio)methyl)-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide, 6-Chloro-3-(((phenylmethyl)thio)methyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, CAS-91-33-8, NCGC00016347-01, SMR000058805, DSSTox_CID_2658, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-((benzylthio)menthyl)-6-chloro-, 1,1-dioxide, 3-((Benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine-1,1-dioxide, 3-Benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, DSSTox_RID_76677, DSSTox_GSID_22658, 3-(benzylsulfanylmethyl)-6-chloro-1,1-dioxo-4H-1, 3-[(Benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-3-{[(phenylmethyl)thio]methyl}-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, SR-05000001574, Benzthiazid, 3-(benzylsulfanylmethyl)-6-chloro-1,1-dioxo-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Benzthiazide [USP:INN:BAN:JAN], Dihydrex (TN), Prestwick_993, Aquatag (TN), Diucen (TN), Edemax (TN), Foven (TN), Spectrum_000076, AC1L1DGU, AC1Q6TPO, Opera_ID_1644, Prestwick0_000824, Prestwick1_000824, Prestwick2_000824, Prestwick3_000824, Spectrum2_001141, Spectrum3_000315, Spectrum4_000250, Spectrum5_000882, D0L2MX, SCHEMBL26257, BSPBio_000747, BSPBio_001910, KBioGR_000660, KBioSS_000476, DivK1c_000491, SPECTRUM1500141, SPBio_001061, SPBio_002668, BPBio1_000823, GTPL7125, CHEMBL1201039, DTXSID4022658, CTK8F7985, HMS501I13, KBio1_000491, KBio2_000476, KBio2_003044, KBio2_005612, KBio3_001410, MolPort-003-666-130, MolPort-003-940-508, NDTSRXAMMQDVSW-UHFFFAOYSA-N, NINDS_000491, HMS1570F09, HMS1920G11, HMS2091M13, HMS2097F09, HMS2234J10, HMS3370L07, HMS3714F09, Pharmakon1600-01500141, ZINC3871698, Tox21_110387, 2262AH, CCG-40326, NSC755902, AKOS015889538, Tox21_110387_1, API0008565, DB00562, MCULE-7096059645, NSC-755902, IDI1_000491, NCGC00016347-02, NCGC00016347-03, NCGC00016347-04, NCGC00016347-07, NCGC00094599-01, NCGC00094599-02, LS-40432, SBI-0051294.P003, FT-0622764, ST51014925, C07759, D00651, AB00051924_04, AB00051924_05, SR-05000001574-1, SR-05000001574-2, BRD-K21450440-001-05-4, BRD-K21450440-001-08-8, I01-19698, Z1692496506, 3-((Benzylthio)methyl)-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-((benzylthio)methyl)-6-chloro-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, 3-(benzylsulfanylmethyl)-6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 3-[(Benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide #, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(((phenylmethyl)thio)methyl)-, dioxide-1,1-, 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-1,1-dioxo-3-[(phenylmethylthio)methyl]-4H-benzo[e]1,2,4-thiadiazine-7 -sulfonamide

ID: 1458

InChIKey: NDTYTMIUWGWIMO-UHFFFAOYSA-N
SMILES: CC(=C)C1CCC(=CC1)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10819
synonyms found at PubChem are:
PERILLYL ALCOHOL, Perilla alcohol, 536-59-4, Perillol, Isocarveol, p-Mentha-1,8-dien-7-ol, Hydrocumin alcohol, 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-, 4-Isopropenylcyclohex-1-en-1-ylmethanol, 4-Isopropenyl-cyclohex-1-ene-1-methanol, Dihydrocuminyl alcohol, 4-Isopropenyl-1-cyclohexene carbinol, 4-(1-Methylethenyl)-1-cyclohexene-1-methanol, Iso-carveol, 1-Hydroxymethyl-4-isopropenyl-1-cyclohexene, NSC 641066, FEMA No. 2664, Dihydrocuminic alcohol, (4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl)methanol, [4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol, EINECS 208-639-9, 1,8-p-Menthadien-7-ol, Cyclohex-1-ene-1-methanol, 4-(1-methylethenyl)-, Para-mentha-1,8-dien-7-ol, Perillic alcohol, CHEBI:15420, NDTYTMIUWGWIMO-UHFFFAOYSA-N, (4-(prop-1-en-2-yl)cyclohex-1-enyl)methanol, perill alcohol, 1-perillalcohol, CCRIS 8461, dihydrocuminyl alcoholn, l(-)-perillyl alcohol, Perillyl alcohol, WARF, Spectrum2_000838, Spectrum3_001974, D0S2HO, AC1L1W0K, cyclohex-1-ene-1-methanol, 4(1-methylethenyl), BSPBio_003574, SCHEMBL296111, SPECTRUM1505297, SPBio_000795, CHEMBL444711, DTXSID4052180, KBio3_002951, MolPort-003-665-516, 4-Isopropenyl-1-cyclohexene-methanol, CCG-40267, 4-isopropenyl-cyclohex-1-enylmethanol, Monoterpenes, University of Wisconsin, AKOS006227854, (4-isopropenylcyclohexen-1-yl)methanol, LS-2891, MCULE-1420218917, NE10108, SDCCGMLS-0066882.P001, KS-000010N6, NCGC00095297-01, NCGC00095297-02, NCGC00095297-03, AN-21302, KB-49924, Perillyl alcohol, University of Wisconsin, (4-Isopropenyl-1-cyclohexen-1-yl)methanol, DB-071728, (4-prop-1-en-2-ylcyclohexen-1-yl)methanol, FT-0627990, ST24034586, SR-05000002384, SR-05000002384-1, BRD-A13323580-001-03-0, I14-15649, F9405E33-6136-4D27-A15E-C10CDC8C9AC4, 1406-56-0, 66141-69-3, 7644-38-4

ID: 1459

InChIKey: NETGEQWGGLFVRL-UHFFFAOYSA-N
SMILES: CC(CO)(C1CC2=C(C3=CC=CC=C3N=C2O1)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 442897
synonyms found at PubChem are:
Dubinidine, 22964-77-8, AC1L9DLN, Prestwick0_001085, CHEBI:4722, 2-(4-methoxy-2,3-dihydrofuro[2,3-b]quinolin-2-yl)propane-1,2-diol, SMR000137322, SR-01000075830, 2-(4-methoxy-2,3-dihydrofuro[2,3-b]quinolin-2-yl)-1,2-propanediol, Prestwick1_001085, Prestwick2_001085, Prestwick3_001085, C10662, Cambridge id 5255767, TimTec1_000662, Lopac0_000422, Oprea1_324044, Oprea1_376629, BSPBio_001130, MLS000532363, MLS001164025, SPBio_003025, BPBio1_001244, CHEMBL1255737, DTXSID30331995, MolPort-001-636-370, HMS1535O02, HMS1571I12, HMS2098I12, HMS2502L12, BBL028479, STL372640, AKOS001581112, AKOS021831421, CCG-202836, MCULE-3827125452, ACM22964778, NCGC00015366-02, NCGC00015366-03, NCGC00015366-03!DUBINIDINE, NCGC00093845-01, NCGC00093845-02, ST005175, AB00514037, EU-0100422, D 7814, SR-01000075830-1, SR-01000075830-6, BRD-A99571536-001-04-4, 2-(4-methoxy-2,3-dihydrofuro[2,3-b]quinolin-2-yl)propane-1,2, 2-(4-methoxy-2,3-dihydrofurano[2,3-b]quinolin-2-yl)propane-1,2-diol

ID: 1460

InChIKey: NFACJZMKEDPNKN-UHFFFAOYSA-N
SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5853
synonyms found at PubChem are:
Metrifonate, TRICHLORFON, Chlorophos, Trichlorphon, Metriphonate, Methyl chlorophos, Bilarcil, Chlorofos, 52-68-6, Chloroftalm, Chloroxyphos, Dipterex, Foschlor, Neguvon, Ricifon, Dylox, Agroforotox, Chlorophthalm, Fliegenteller, Hypodermacid, Khloroftalm, Polfoschlor, Trichlorofon, Trichlorophon, Bovinox, Cekufon, Diptevur, Ditrifon, Forotox, Masoten, Mazoten, Phoschlor, Ritsifon, Sotipox, Volfartol, Votexit, Wotexit, Anthon, Briten, Briton, Combot, Danex, Dyrex, Dyvon, Loisol, Proxol, Soldep, Trinex, Tugon, (+-)-Trichlorfon, Trichlorphon FN, DETF, Equino-Aid, Foschlor R, Chlorophosciclosom, Flibol E, DEP (pesticide), Dipterex 50, Metrifonatum, Trichloorfon, Clorofos, Denkaphon, Dioxaphos, Foschlorem, Chlorak, Dimetox, Phoschlor R50, Bayer L 1359, Dipterex WP 80, Foschlor R-50, Metrifonato, Metriphonatum, Britten, Chlorfos, Chlorphos, Ciclosom, Depthon, Leivasom, Combot equine, Dicontal Fort, Tugon fly bait, Dipterex SL, WEC 50, Ditriphon 50, Tugon stable spray, Foschlor 25, Aerol 1, Bayer L 13/59, Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate, NCI-C54831, Foschlorem [Polish], Trichlorphon [ISO], Satox 20WSC, Trichloorfon [Dutch], Trichlorfon [German], Trichlorfon [USAN], Aerol 1 (pesticide), Caswell No. 385, BAY 15922, Metifonate, Trichlorophone, Dipterax, Neguron, ENT 19,763, Vermicide bayer 2349, OMS 800, Trichlorfon [BSI:ISO], BAY-L 1359, Bayer 15922, Metrifonatum [INN-Latin], Foschlor R-50 (VAN), Metrifonato [INN-Spanish], Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester, CCRIS 1289, HSDB 881, BAY-a 9826, Dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate, NSC 8923, Bayer-L-1359, EINECS 200-149-3, UNII-1MVY4KU98F, UNII-37VCQ9C0OG, EPA Pesticide Chemical Code 057901, Dimethyltrichlorohydroxyethyl phosphonate, BRN 1709434, 1MVY4KU98F, 37VCQ9C0OG, O,O-Dimethyl-1-oxy-2,2,2-trichloroethyl phosphonate, Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate, AI3-19763, MLS000069726, CHEBI:6908, CHEMBL167150, O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate, O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate, O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphosaeure ester, NFACJZMKEDPNKN-UHFFFAOYSA-N, Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-, dimethyl ester, Dimethyl 1-hydroxy-2,2,2-trichloroethyl phosphonate, Trichlorfon (USAN), O,O-Dimethyl (1-oxy-2,2,2-trichloroethyl)phosphonate, O,O-Dimethyl-(1-hydroxy-2,2,2-trichlorathyl)-phosphat, O,O-Dimethyl-1-hydroxy-2,2,2-trichloroethylphosphonate, O,O-Dimetil-(2,2,2-tricloro-1-idrossi-etil)-fosfonato, 1-Hydroxy-2,2,2-trichloro-ethyle phosphonate de dimethyle, Dimethoxy-2,2,2-trichloro-1-hydroxy-ethyl phosphine oxide, Dimethoxy-2,2,2-trichloro-1-hydroxy-ethyl-phosphine oxide, O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosponate, O,O-Dimethyl-(2,2,2-trichlor-1-hydroxy-aethyl)phosphonat, NCGC00018237-03, O,O-Dimethyl-(2,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat, SMR000058176, Dimethyl (trichlorohydroxyethyl)phosphonate, (2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester, (2,2,2-Trichloro-1-hydroxyethyl)-phosphonic acid dimethyl ester, 1-Hydroxy-2,2,2-trichloro-ethyle phosphonate de dimethyle [French], O,O Dimetil 2,2,2-trichloro 1 hidroxietil fosfonato (Portugese), O,O-Dimethyl-(1-hydroxy-2,2,2-trichlorathyl)-phosphat [German], O,O-Dimethyl-(2,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat [Dutch], O,O-Dimethyl-(2,2,2-trichlor-1-hydroxy-aethyl)phosphonat [German], O,O-Dimetil-(2,2,2-tricloro-1-idrossi-etil)-fosfonato [Italian], DSSTox_CID_1389, 2,2,2-trichloro-1-dimethoxyphosphorylethanol, O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphonsaeure ester [German], DSSTox_RID_76131, DSSTox_GSID_21389, Dimethyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate, Q-201859, Clorofos [Russian], C4H8Cl3O4P, Ertefon, Memobay, Zeltivar, Onefon, ProMem, CAS-52-68-6, (+)-Trichlorfon, (-)-Trichlorfon, Phoschlor R.50, Prestwick_599, Clorofos [Russian], Metrifonate [INN], Foschlor R 50, Totalene (Salt/Mix), Metrifonate, (+)-, Metrifonate, (-)-, TRI CHLORFON, Opera_ID_345, AC1Q4GEJ, Metrifonate (USP/INN), Prestwick0_000051, Prestwick1_000051, Prestwick2_000051, Prestwick3_000051, (.+/-.)-Trichlorfon, AC1L1LA2, cid_5853, Bay-a-9826, SCHEMBL15972, BSPBio_000201, SPBio_002122, WLN: GXGGYQPO&O1&O1, BPBio1_000223, O,2,2-trichlorathyl)-phosphat, O,2,2-trichloroethyl)phosphate, DTXSID0021389, NSC8923, MolPort-001-797-006, HMS1568K03, HMS2095K03, methyl(14c)methyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate, Pharmakon1600-01505765, HY-B1220, NSC-8923, Tox21_110843, Tox21_201607, Tox21_300860, BDBM50286920, LS-175, MFCD00055272, NSC759241, O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphonsaeure ester, AKOS001499170, AKOS022032084, Tox21_110843_1, CCG-213546, CS-4845, MCULE-8125791587, NSC-759241, O,2,2-trichlorohydroxyethyl)phosphonate, NCGC00018237-02, NCGC00018237-04, NCGC00018237-06, NCGC00018237-07, NCGC00018237-09, NCGC00089822-02, NCGC00089822-03, NCGC00254763-01, NCGC00259156-01, O,2,2-trichloraethyl)phosphosaeure ester, AN-24406, O,2,2-tricloro-1-idrossi-etil)-fosfonato, SBI-0206912.P001, 0,2,2-trichloro-1-hydroxyethyl)phosphonate, O,2,2-trichloro-1-hydroxyethyl)phosphonate, O,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat, O,2,2-trichlor-1-hydroxy-aethyl)phosphonat, 2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol, C07971, D00805, Trichlorfon, PESTANAL(R), analytical standard, 26855-EP2280009A1, 26855-EP2292608A1, 26855-EP2305662A1, 26855-EP2308857A1, 26855-EP2314583A1, 31359-EP2274983A1, 31359-EP2308858A1, 31359-EP2311816A1, 31359-EP2311817A1, 90713-EP2305640A2, SR-01000000181, Dimethyl (1-hydroxy-2,2-trichloroethyl)phosphonate, Dimethyl (2,2-trichloro-1-hydroxyethyl)phosphonate, Dimethyl 1-hydroxy-2,2,2-trichloroethylphosphonate, SR-01000000181-2, (2,2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate, [(2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate], O,O-Dimethyl (2,2,2-trichlorohydroxyethyl)phosphonate, Phosphonic acid,2,2-trichloroethyl)-, dimethyl ester, trichloro-alpha-hydroxyethyl phosphonic dimethyl ester, 1-Hydroxy-2,2-trichloro-ethyle phosphonate de dimethyle, Dimethoxy-(2,2-trichloro-1-hydroxyethyl)phosphine oxide, O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphate, (2,2-Trichloro-1-hydroxy)phosphonic acid, dimethyl ester, (2,2-Trichloro-1-hydroxyethyl)phosphonate, dimethyl ester, Dimethoxy-(2,2,2-trichloro-1-hydroxyethyl)phosphine oxide, Metrifonate, European Pharmacopoeia (EP) Reference Standard, (1-Hydroxy-2,2-trichloroethyl)phosphonic acid, dimethyl ester, (2,2,2-Trichloro-1-hydroxyethyl)phosphonate, dimethyl ester, (2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester, 1-Hydroxy-2,2,2-trichloroethylphosphonate-O,O-dimethyl ester, Phosphonic acid,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid, dimethyl ester, 2,2-TRICHLORO-1-HYDROXYETHYL)PHOSPHONIC ACID, DIMETHYL ESTER, Trichlorfon, United States Pharmacopeia (USP) Reference Standard, Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (+)-, Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (-)-, Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, InChI=1/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H, Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (+)-, Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (-)-, 37333-09-8, 50924-44-2, 56042-25-2, 56042-26-3, 56042-27-4, 66758-31-4

ID: 1461

InChIKey: NFBAXHOPROOJAW-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4760
synonyms found at PubChem are:
phenindione, 2-Phenyl-1,3-indandione, 83-12-5, Dindevan, Phenylindanedione, 2-Phenyl-1H-indene-1,3(2H)-dione, Athrombon, Diophindane, Emandione, Fenhydren, Phenhydren, Phenillin, Phenylindione, Phenyline, Rectadione, Theradione, Danedion, Fenilin, Pindione, Danilone, Diadilan, Emandion, Eridione, Fenindion, Hemolidione, Phenylen, Phenylin, Tromazal, Bindan, Danilon, Dineval, Hedulin, Indema, Trombol, Indon, Cronodione, Thrombasal, Indion, 2-Phenylindandione, Fenindiona, Phenindionum, 2-Phenyl-1,3-diketohydrindene, Phenyllin, 1H-Indene-1,3(2H)-dione, 2-phenyl-, 2-Phenyl-1,3-indanedione, Fenindiona [INN-Spanish], Phenindionum [INN-Latin], 1,3-Indandione, 2-phenyl-, 2-phenyl-2,3-dihydro-1H-indene-1,3-dione, Fenindione, 2-Fenyloindandion-1,3, Phenindione [INN:BAN], 2-Fenyloindandion-1,3 [Polish], 2-Phenylindan-1,3-dione, 2-phenylindane-1,3-dione, 2-phenylindene-1,3-dione, Hedulin (TN), Phenindione (INN), UNII-5M7Y6274ZE, HSDB 3155, 2-phenyl-1,3(2H)-Indenedione, C15H10O2, EINECS 201-454-4, NSC 41693, CHEMBL711, MLS000069422, CHEBI:8066, NFBAXHOPROOJAW-UHFFFAOYSA-N, 5M7Y6274ZE, CAS-83-12-5, NCGC00016329-01, SMR000059058, P1029, DSSTox_CID_3453, DSSTox_RID_77033, DSSTox_GSID_23453, SR-01000721861, 2 Phenyl 1,3 indandione, Phenindion, phenylindandione, Phenindione [USP:INN:BAN], Prestwick_872, Phenindione(Rectadione), Spectrum_000927, Phenindione (Rectadione), AC1Q6DEB, Opera_ID_1966, Prestwick0_000538, Prestwick1_000538, Prestwick2_000538, Prestwick3_000538, Spectrum2_000999, Spectrum3_000710, Spectrum4_000476, Spectrum5_001070, ACMC-1BM0O, Boots Brand of Phenindione, D08FTG, AC1L1IW5, 2-Phenyl-indan-1,3-dione, 1H-Indene-1, 2-phenyl-, Oprea1_684242, SCHEMBL33831, BSPBio_000555, BSPBio_002499, KBioGR_000952, KBioSS_001407, P26406_ALDRICH, MLS001148439, Dindevan,Rectadione;Rectadione, DivK1c_000307, SPECTRUM1500477, SPBio_001097, SPBio_002476, BPBio1_000611, Goldshield Brand of Phenindione, GTPL6838, DTXSID5023453, CTK5F0412, HMS500P09, KBio1_000307, KBio2_001407, KBio2_003975, KBio2_006543, KBio3_001719, KS-00000YJG, MolPort-001-783-429, NINDS_000307, WLN: L56 BV DV CHJ CR, HMS1569L17, HMS1920F20, HMS2091N22, HMS2096L17, HMS2234N06, HMS3651M04, HMS3713L17, Pharmakon1600-01500477, 2-Phenyl-1,3-indandione, 97%, HY-B0325, NSC41693, 1,3(2H)-Indenedione, 2-phenyl-, Tox21_110375, ANW-13618, BBL011710, BDBM50280157, CCG-40217, NSC-41693, NSC757269, s1921, STK395038, AKOS000445019, Tox21_110375_1, ZINC100004862, CS-2366, DB00498, MCULE-1090571544, Merck Lipha Sante Brand of Phenindione, NE30721, NSC-757269, 1H-Indene-1,3(2H)-dione,2-phenyl-, IDI1_000307, NCGC00016329-02, NCGC00016329-03, NCGC00016329-04, NCGC00016329-05, NCGC00016329-07, NCGC00094756-01, NCGC00094756-02, NCGC00094756-03, NCGC00094756-04, LS-81254, Q565, SBI-0051480.P003, AB2000376, TR-025910, AB00052069, ST45021959, C07584, D08354, AB00052069_13, AB00052069_14, SR-01000721861-2, SR-01000721861-3, 2-phenyl-2-hydrocyclopenta[1,2-a]benzene-1,3-dione, BRD-K70592963-001-21-7, BRD-K70592963-001-26-6, Phenindione, United States Pharmacopeia (USP) Reference Standard, InChI=1/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13

ID: 1462

InChIKey: NFDFQCUYFHCNBW-SCGPFSFSSA-N
SMILES: C/C=C(/C(=C/C)/C1=CC=C(C=C1)O)\C2=CC=C(C=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 667476
synonyms found at PubChem are:
dienestrol, Dienoestrol, Dehydrostilbestrol, 84-17-3, Cycladiene, Synestrol, Dienol, Estraguard, Follidiene, Restrol, Dehydrostilboestrol, Dienestrolum, Oestrodienol, Dienesterol, Estragard, Hormofemin, Oestrovis, Willnestrol, (E,E)-Dienestrol, alpha-Dienestrol, para-Dien, E,E-Dienestrol, Dienestrol (E,E), Dienestrolo, Dienoestrol bp, Estrodienol, Oestrodiene, Oestrasid, Di(p-oxyphenyl)-2,4-hexadiene, 13029-44-2, Dienestrolo [DCIT], p,p'-(Diethylideneethylene)diphenol, Dinestrol, Estroral, Follormon, Gynefollin, Oestroral, Sexadien, Teserene, Agaldog, Dinovex, Retalon, 4,4'-(Diethylideneethylene)diphenol, 3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene, Dienestrolum [INN-Latin], UNII-RRW32X4U1F, Dienestrol, (E,E)-Isomer, MLS000069528, 3,4-Bis(p-hydroxyphenyl)-2,4-hexadiene, 4,4'-hexa-2,4-diene-3,4-diyldiphenol, Di(para-oxyphenyl)-2,4-hexadiene, Dienestrol (USP/INN), NSC 59809, 4,4'-(1,2-Diethylidene-1,2-ethanediyl)bisphenol, RRW32X4U1F, Isodienestrol, Phenol, 4,4'-(diethylideneethylene)di-, DV (TN), para,para'-(Diethylideneethylene)diphenol, SMR000058597, 4,4'-Hydroxy-gamma,delta-diphenyl-beta,delta-hexadiene, 3,4-Bis(para-hydroxyphenyl)-2,4-hexadiene, 2,4-Hexadiene, 3,4-bis(4-hydroxyphenyl)-, NFDFQCUYFHCNBW-SCGPFSFSSA-N, Dienoestrol [Nonsteroidal oestrogens], 4,4'-Dihydroxy-gamma,delta-diphenyl-beta,delta-hexadiene, Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-, 4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol, Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-, (E,E)-, DSSTox_CID_2382, DSSTox_RID_76566, DSSTox_GSID_22382, 4,4'-(2E,4E)-hexa-2,4-diene-3,4-diyldiphenol, CCRIS 9121, HSDB 3313, Phenol, 4,4'-(diethylideneethylene)di-, trans-, (E,E)-, Phenol, 4,4'-((1E,2E)-1,2-diethylidene-1,2-ethanediyl)bis-, EINECS 201-519-7, DV, Dienestrol [INN], SR-01000003032, CHEBI:4518, Dienestrol [USP:INN:BAN], CAS-84-17-3, Prestwick_52, NCGC00016335-01, Restrol, Dienestrol, (E,E)-4,4'-(Diethylideneethylene)diphenol, Opera_ID_421, alpha-dienestrol diacetate, Prestwick2_000798, Prestwick3_000798, Spectrum5_000875, D09ZQN, AC1LDI60, CHEMBL1018, SCHEMBL52170, BSPBio_000936, BSPBio_002177, MLS001077274, MLS002207222, MLS002222156, SPECTRUM1500241, AC1Q7B18, BPBio1_001030, cid_667476, GTPL7160, SCHEMBL2896853, ZINC1283, DTXSID7022382, BDBM40491, HMS502G13, MolPort-046-033-444, HMS1570O18, HMS1920G04, HMS2091M14, HMS2097O18, HMS2232M11, HMS3714O18, Pharmakon1600-01500241, HY-B1403, Tox21_110378, 2375AH, CCG-40189, NSC756734, AKOS015902490, Tox21_110378_1, CS-4911, DB00890, NSC-756734, IDI1_000771, NCGC00018153-03, NCGC00018153-04, NCGC00018153-05, NCGC00018153-06, NCGC00018153-07, NCGC00018153-10, NCGC00022210-03, NCGC00022210-04, NCGC00178779-01, NCGC00178779-02, AC-13162, AN-24070, SBI-0051344.P003, AB2000337, LS-104381, TR-026060, D0449, C08090, D00898, Dienestrol, VETRANAL(TM), analytical standard, AB00051967_16, J-005782, SR-01000003032-2, SR-01000003032-4, 4,4'-((2E,4E)-hexa-2,4-diene-3,4-diyl)diphenol, 4,4'-[(2E,4E)-2,4-Hexadiene-3,4-diyl]diphenol, BRD-K55106630-001-01-0, BRD-K95309561-001-05-6, BRD-K95309561-001-15-5, I14-19858, Dienestrol, European Pharmacopoeia (EP) Reference Standard, 4-[(E,1E)-1-ethylidene-2-(4-hydroxyphenyl)but-2-enyl]phenol, Dienestrol, United States Pharmacopeia (USP) Reference Standard, 4,4'-Dihydroxy-.gamma.,.delta.-diphenyl-.beta.,.delta.-hexadiene, Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-, (E,E-(9CI), Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-, (E,E)- (9CI), 22090-87-5

ID: 1463

InChIKey: NFEIBWMZVIVJLQ-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)OCC(C)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 21467
synonyms found at PubChem are:
Mexiletine hydrochloride, 5370-01-4, Mexitil, Mexiletine HCL, Mexiletene hydrochloride, 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride, Mexiletine (hydrochloride), 1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride, 2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride, Ko 1173 Cl, EINECS 226-362-1, KO 1173, NCGC00094121-01, Mexitil (TN), 1-(2,6-Xylyloxy)-2-aminopropane hydrochloride, DSSTox_CID_25783, DSSTox_RID_81125, 1-Methyl-2-(2,6-xylyloxy)ethylammonium chloride, DSSTox_GSID_45783, 1-(2,6-Dimethylphenoxy)-2-propanamine, 1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride, 1-(2,6-Dimethylphenoxy)-2-aminopropane hydrochloride, 2-(2-aminopropoxy)-1,3-dimethylbenzene hydrochloride, Ethylamine, 1-methyl-2-(2,6-xylyloxy)-, hydrochloride, (+-)-1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride, 2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride, (+-)-, CHEBI:6917, SMR000326711, CAS-5370-01-4, 1-(2,6-Xylyloxy)-2-aminopropane, 1-(2,6-dimethylphenoxy)prop-2-ylamine, chloride, SR-01000075986, NCGC00015659-06, 1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride, mexilitene, Ritalmex, (+)-(S)-Mexiletine Hydrochloride, Katen, Mexiletine, HCl, Prestwick_666, AC1Q3DIN, AC1L2IE1, Ko 1173Cl, SCHEMBL42226, (+)-Mexiletine Hydrochloride, MLS001056756, MLS002222239, MLS002548872, SPECTRUM1503929, MEXILITENE HYDROCHLORIDE, Mexiletine hydrochloride, powder, CHEMBL1200606, DTXSID2045783, KO-1173-Cl, CTK6A8839, MolPort-003-666-510, NFEIBWMZVIVJLQ-UHFFFAOYSA-N, HMS1568B04, KO-1173 CL, Pharmakon1600-01503929, 31828-71-4 (Parent), AC1Q3993, BCP28602, EBD30089, HY-A0093, KS-00000F9V, Tox21_111249, Tox21_500784, ANW-41640, Mexiletine hydrochloride [USAN:JAN], MFCD00216024, NSC758639, s4225, SBB003392, Mexiletine hydrochloride (JP17/USP), AKOS009139802, Tox21_111249_1, Tox21_111249_2, AC-4260, AC-8240, AN-8177, CCG-213246, LP00784, MCULE-4507699259, NC00682, NSC-758639, VA11290, NCGC00015659-14, NCGC00094121-02, NCGC00094121-03, NCGC00094121-04, NCGC00261469-01, AS-13790, BC681107, CPD000326711, LS-68258, Mexiletine hydrochloride [USAN:USP:JAN], SAM002264606, SC-17488, ST083488, TL8000021, TR-019000, EU-0100784, FT-0082653, M2040, ST24048103, V0364, EN300-53944, D00639, J10321, M 2727, M-2016, 1-(2,6-dimethylphenoxy)propan-2-aminhydrochlorid, 370M014, 1-(2,6-dimethylphenoxy)-2-propananmineHydrochloride, 1-Methyl-2-(2,6-xylyloxy)ethylamine Hydrochloride, I01-3629, SR-01000075986-1, SR-01000075986-6, W-105713, 1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride, 1-(2,6-dimethylphenoxy)-2-amino-propane hydrochloride, 1-(2,6-dimethylphenoxy)-2-amino-propane hydrochloride;, (2S)-1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride, 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride, 97%, Mexiletine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Mexiletine hydrochloride, United States Pharmacopeia (USP) Reference Standard, AKOS026750013, FT-0601136, AC1Q1RX7, 1-(2,6-dimethylphenoxy)propan-2-aminium chloride, 2-(2-azaniumylpropoxy)-1,3-dimethylbenzene chloride

ID: 1464

InChIKey: NFJVELXCUBWAFL-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C(=C1)O)C(=O)C2=CC=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3938139
synonyms found at PubChem are:
Cearoin, 52811-37-7, SPBio_002047, Spectrum_000592, SpecPlus_000118, Spectrum2_001954, Spectrum3_001305, Spectrum4_001597, Spectrum5_000314, BSPBio_002969, KBioGR_002214, KBioSS_001072, SPECTRUM290030, DivK1c_006214, AC1N0I27, SCHEMBL4928735, CHEMBL1613209, KBio1_001158, KBio2_001072, KBio2_003640, KBio2_006208, KBio3_002189, DTXSID20398097, CHEBI:109547, CCG-39472, SDCCGMLS-0066944.P001, NCGC00095562-01, NCGC00095562-02, (2,5-dihydroxy-4-methoxyphenyl)-phenylmethanone, BRD-K20420220-001-03-9

ID: 1465

InChIKey: NFLLKCVHYJRNRH-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Cl.CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 10660
synonyms found at PubChem are:
DIMENHYDRINATE, Dramamine, 523-87-5, Vomex A, Chloranautine, Diphenhydrinate, Anautine, Travelin, Amosyt, Aviomarin, Gravol, Menhydrinate, Andramine, Antemin, Diamarin, Dimenest, Dimentabs, Dramalen, Dramamin, Dramarin, Dramilin, Eldodram, Gravinol, Hydrinate, Novamine, Permital, Supremal, Teodramin, Travelmin, Troversin, Xamamina, Dimate, Dramyl, Dromyl, Reise-Engletten, Neo-Navigan, Theohydramine, Dommanate, Lomarin, Reidamine, Removine, Emedyl, Faston, Diphenhydramine Theoclate, Novamin (VAN), Gravinol (antiemetic), Dimenidrinato [DCIT], UNII-JB937PER5C, JB937PER5C, Dimenhydrinatum [INN-Latin], Dimenhidrinato [INN-Spanish], CCRIS 4798, HSDB 3064, Dramamine (TN), NCI-C60639, Diphenhydramine 8-chlorotheophylline, EINECS 208-350-8, Diphenhydramine 8-chlorotheophyllinate, NSC 117855, 2-(Diphenylmethoxy)-N,N-dimethylethylamine 8-chlorotheophyllinate, 2-(Benzhydryloxy)-N,N-dimethylethylamine compd. with 8-chlorotheophylline, 1H-Purine-2,6-dione, 8-chloro-3,7-dihydro-1,3-dimethyl-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), C24H28ClN5O3, O-Benzhydryldimethylaminoethanol 8-chlorotheophyllinate, (o-Benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate, Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline, 2-(Benzhydryloxy)-N,N-dimethylethylamine 8-chlorotheophyllinate, N,N-Dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, beta-Dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine, 8-Chlorotheophylline, compd. with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1), 8-Chlorotheophylline, compound with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1), Ethylamine 2-(diphenylmethoxy)-N,N-dimethyl-, compd with 8-chlorotheophylline (1:1), Ethylamine, 2-(diphenylmethoxy)-N, N-dimethyl-, compd. with 8-chlorothiophylline (1:1), Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-, compd. with 8-chlorotheophylline, Theophylline, 8-chloro-, compd with 2-(diphenylmethoxy)-N,N-dimethyethylamine (1:1), Theophylline, 8-chloro-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1), 1H-Pyrine-2,6-dione, 8-chloro-3,7-dihydro-1,3-dimethyl-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, compd. with 8-chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1), SR-05000001608, [o-Benzhydryl(dimethylamino)ethanol] 8-chlorotheophyllinate, Dimenhydrinat, Dimenidrinato, 2-benzhydryloxy-N,N-dimethylethanamine;8-chloro-1,3-dimethyl-7H-purine-2,6-dione, 2-(diphenylmethoxy)-N,N-dimethylethanamine and 8-chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione, Dimenhydrinate,(S), Spectrum_000974, Prestwick3_000265, Spectrum2_000992, Spectrum3_000397, Spectrum4_000517, Spectrum5_000909, DSSTox_CID_5087, AC1L1VO8, AC1Q6L8T, SCHEMBL5128, DSSTox_RID_77660, DSSTox_GSID_25087, BSPBio_000110, BSPBio_002213, KBioGR_001093, KBioSS_001454, DivK1c_000049, SPECTRUM1500251, SPBio_001083, BPBio1_000122, Dimenhydrinate [INN:BAN:JAN], CHEMBL1200406, CHEBI:94848, HMS500C11, KBio1_000049, KBio2_001454, KBio2_004022, KBio2_006590, KBio3_001433, C17H22NO.C7H6ClN4O2, Dimenhydrinate (JP17/USP/INN), MolPort-003-666-165, NFLLKCVHYJRNRH-UHFFFAOYSA-N, NINDS_000049, HMS1920G20, HMS2091O08, HMS2095F12, HMS3712F12, Pharmakon1600-01500251, diphenhydramine promethazine teoclate, HY-B1215, Dimenhydrinate [USP:INN:BAN:JAN], Tox21_200323, 8-chlorotheophylline; diphenhydramine, CCG-40210, MFCD00054265, NSC117855, NSC756740, AKOS015896341, AC-8241, AN-8178, CS-4841, LS-1322, NSC-117855, NSC-756740, IDI1_000049, NCGC00021154-01, NCGC00021154-02, NCGC00021154-03, NCGC00021154-04, NCGC00021154-05, NCGC00021154-06, NCGC00021154-07, NCGC00091928-01, NCGC00091928-02, NCGC00091928-03, NCGC00257877-01, AS-13166, BC204742, H496, SBI-0051350.P003, AB00053833, FT-0625019, FT-0696921, D00520, J10430, WLN: T56 BM DN FNVNVJ CG F H &622, 523D875, I06-2042, SR-05000001608-1, SR-05000001608-2, BRD-M98649031-001-01-1, Dimenhydrinate, European Pharmacopoeia (EP) Reference Standard, Dimenhydrinate, United States Pharmacopeia (USP) Reference Standard, Ethylamine 2-(diphenylmethoxy)-N, compd. with 8-chlorotheophylline (1:1), Theophylline, compd. with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1), 2-benzhydryloxy-N,N-dimethyl-ethanamine; 8-chloro-1,3-dimethyl-7H-purine-2,6-dione, 2-benzhydryloxy-N,N-dimethylethanamine; 8-chloro-1,3-dimethyl-7H-purine-2,6-dione, Dimenhydrinate for peak identification, European Pharmacopoeia (EP) Reference Standard, Dimenhydrinate, Pharmaceutical Secondary Standard; Certified Reference Material, Theophylline, compd. with 2-(diphenylmethoxy)-N,N-(dimethylethyl)amine (1:1), 133294-22-1, 1H-Purine-2, 8-chloro-3,7-dihydro-1,3-dimethyl-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), 8-chloro-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione compound with 2-(benzhydryloxy)-N,N-dimethylethanamine (1:1), Diphenhydramine [2-(diphenylmethoxy)-N,N-dimethylethan-amine] 8-chlorotheophylline (8-chloro-1,3-dimethyl-3,7-dihy-dro-1H-purine-2,6-dione)

ID: 1466

InChIKey: NFSTZPMYAZRZPC-UHFFFAOYSA-N
SMILES: C1=CC2=C(NN=C2C(=C1)[N+](=O)[O-])Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1649
synonyms found at PubChem are:
3-Bromo-7-nitro-1H-indazole, 3-bromo-7-nitroindazole, 74209-34-0, 1H-Indazole,3-bromo-7-nitro-, 3-bromo-7-nitro-2H-indazole, CHEMBL479014, NFSTZPMYAZRZPC-UHFFFAOYSA-N, MFCD00159910, SR-01000075708, BRNI, 3-bromo-7NI, 3-Br-7-Nitroindazole, Tocris-0735, AC1L1BXC, Lopac-B-2050, D0U6ZT, D0X5QJ, 3-Br-7NI, Lopac0_000161, BSPBio_001502, BSPBio_002434, KBioGR_000222, KBioSS_000222, SCHEMBL499421, SCHEMBL499422, SPECTRUM1505105, GTPL5113, BCBcMAP01_000129, CTK5D9545, KBio2_000222, KBio2_002790, KBio2_005358, KBio3_000443, KBio3_000444, DTXSID90274319, OR6862T, 3-Bromo-7-nitro-1H-indazole #, 7-NITROINDAZOLE, 3-BROMO, MolPort-001-684-155, Bio1_000424, Bio1_000913, Bio1_001402, Bio2_000222, Bio2_000702, HMS1361L04, HMS1791L04, HMS1989L04, HMS3260B03, HMS3266N19, HMS3402L04, HMS3649K16, KS-000006NQ, ZINC3870920, ZX-AT001376, Tox21_500161, ANW-57370, BDBM50270528, BS0227, HSCI1_000239, SBB099519, AKOS005070136, CB-3929, CCG-204256, CS-W020666, DB01997, FCH1322644, LP00161, MCULE-1752377285, PB13032, RP13826, TRA0074231, VI20026, IDI1_033972, NCGC00015143-01, NCGC00015143-02, NCGC00015143-03, NCGC00015143-04, NCGC00015143-05, NCGC00015143-06, NCGC00015143-07, NCGC00015143-08, NCGC00015143-09, NCGC00015143-10, NCGC00024756-01, NCGC00024756-02, NCGC00024756-03, NCGC00024756-04, NCGC00024756-05, NCGC00024756-06, NCGC00024756-07, NCGC00024756-08, NCGC00260846-01, AJ-46338, AK-27879, KB-87037, QC-10364, SC-61310, AB0038182, AX8085266, ST1100585, TR-023986, B6426, EU-0100161, FT-0615185, ST50306995, Y5539, 09B340, A15784, A15928, B 2050, Q-1092, 1W-0945, 3-Bromo-7-nitroindazole, >=98% (TLC), powder, I10-1086, I10-1446, SR-01000075708-1, SR-01000075708-3, SR-01000075708-6, BRD-K24689407-001-03-0, BRD-K24689407-001-04-8, BRD-K24689407-001-05-5

ID: 1467

InChIKey: NGBFQHCMQULJNZ-UHFFFAOYSA-N
SMILES: CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 41781
synonyms found at PubChem are:
Torasemide, TORSEMIDE, 56211-40-6, Demadex, Torasemida, Torasemidum, Luprac, Torasemidum [INN-Latin], Torasemida [INN-Spanish], Toradiur, Torsemide [USAN], Dilutol, Presoril, Torocard, Sutril, Torrem, Torem, Unat, JDL 464, Torasemide N, N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide, UNII-W31X2H97FB, Torsemide (USP), 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, Demadex (TN), AC 4464, Luprac (TN), Torsemide (Demadex), CCRIS 6736, BM 02015, BM-02015, Torasemide (JAN/INN), AC4464, AC-4464, BRN 0498515, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide, MLS001165687, CHEBI:9637, W31X2H97FB, JDL-464, Torasemide, Anhydrous, GJ-1090, KS-1123, PW-2132, NCGC00016879-01, SMR000466313, 1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea, 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea, CAS-56211-40-6, DSSTox_CID_3690, DSSTox_RID_77149, DSSTox_GSID_23690, Q-201846, 4-[(3-methylphenyl)amino]-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide, N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide, 3-Pyridinesulfonamide, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-, 3-Pyridinesulfonamide, N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-, n-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide, N-{[(1-methylethyl)amino]carbonyl}-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide, Torsemide [USAN:USP], Demadex, Torsemide, Torasemide [INN], PubChem18545, Spectrum_001776, AC1Q6UVM, Prestwick0_001030, Prestwick1_001030, Prestwick2_001030, Prestwick3_001030, Spectrum2_001142, Spectrum3_001832, Spectrum4_000290, Spectrum5_001699, D0J9XZ, CHEMBL1148, SCHEMBL41184, BSPBio_001219, BSPBio_003503, KBioGR_000820, KBioSS_002257, cid_41781, MLS000759418, MLS001195611, MLS001424121, MLS006010744, BIDD:GT0623, SPECTRUM1505211, SPBio_001063, SPBio_003080, AC1L26H7, BPBio1_001341, GTPL7312, ZINC5823, DTXSID2023690, BDBM64107, CTK8B3035, KBio2_002256, KBio2_004824, KBio2_007392, KBio3_003008, MolPort-002-885-870, NGBFQHCMQULJNZ-UHFFFAOYSA-N, HMS1571M21, HMS1922N05, HMS2051L21, HMS2098M21, HMS2234N14, HMS3373G20, HMS3393L21, HMS3715M21, ALBB-027267, BCP07286, HY-B0247, ZX-AN025776, Tox21_110662, AN-919, ANW-41652, BG0484, CCG-40257, CT0260, MFCD00866166, s1698, STL388026, Torsemide, >=98% (HPLC), solid, AKOS015894937, Tox21_110662_1, API0004454, CS-2227, DB00214, MCULE-2734924315, NC00238, VA11897, NCGC00016879-02, NCGC00016879-03, NCGC00016879-04, NCGC00016879-06, NCGC00016879-07, NCGC00095141-01, NCGC00095141-02, NCGC00095141-03, AC-18762, BM02.015, CC-35108, CPD000466313, SAM001246567, SC-13773, ACM1189375061, AB0006854, AB2000227, LS-131973, TL8003646, TR-019752, AB00514011, FT-0630689, R3923, D00382, AB00514011-09, AB00514011_10, AB00514011_11, 211T406, A830961, C-20564, SR-01000759362, I06-0056, SR-01000759362-5, BRD-K30480208-001-05-2, 1-isopropyl-3-[(4-m-toluidino-3-pyridyl) sulfonyl]urea, 1-isopropyl-3-[(4- m -toluidino-3-pyridyl) sulfonyl]urea, 1-isopropyl-3-[[4-(3-methylanilino)-3-pyridyl]sulfonyl]urea, Torsemide, United States Pharmacopeia (USP) Reference Standard, 1-[[4-(3-methylanilino)-3-pyridinyl]sulfonyl]-3-propan-2-ylurea, Torasemide anhydrous, European Pharmacopoeia (EP) Reference Standard, 1-[4-[(3-methylphenyl)amino]pyridin-3-yl]sulfonyl-3-propan-2-yl-urea, 1-{4-[(3-methylphenyl)amino]pyridine-3-sulfonyl}-3-(propan-2-yl)urea, N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide, N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide, 3-pyridinesulfonamide,N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-, N-({4-[(3-methylphenyl)imino]-1,4-dihydropyridin-3-yl}sulfonyl)propane-2-carbamimidic acid, Torasemide for system suitability, European Pharmacopoeia (EP) Reference Standard, ZB000619

ID: 1468

InChIKey: NGEVNHYPVVOXPB-RZZBNZQCSA-N
SMILES: C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)OC(=O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6436903
synonyms found at PubChem are:
Ergosterol Acetate, NGEVNHYPVVOXPB-RZZBNZQCSA-N, Ergosterol, acetate, 2418-45-3, Ergosterin acetate, Ergosteryl acetate, Ergosta-5,7,22-trien-3-beta-yl acetate, Ergosteryl 3.beta.-acetate, EINECS 219-335-0, Ergosta-5,7,22-trien-3.beta.-yl acetate, Ergosta-5,7,22-trien-3.beta.-ol, acetate, AC1O5MMK, (3.beta.,22E)-Ergosta-5,7,22-trien-3-yl acetate, SCHEMBL1640062, ZINC5761091, (22E)-5,7,22-ergostatriene-3beta-yl Acetate, J-015387, (24R)-3beta-Acetoxy-24-methylcholesta-5,7,22-triene, [(3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate

ID: 1469

InChIKey: NGFMICBWJRZIBI-UJPOAAIJSA-N
SMILES: C1=CC=C(C(=C1)CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 439503
synonyms found at PubChem are:
salicin, 138-52-3, Salicoside, Salicine, Salicyl alcohol glucoside, D-(-)-Salicin, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol, Saligenin beta-D-glucopyranoside, 2-(Hydroxymethyl)phenyl beta-D-glucopyranoside, D-Salicin, Saligenin-beta-D-glucopyranoside, Salicin (6CI,8CI), D(-)-Salicin, 2-(Hydroxymethyl)phenyl-beta-d-glucopyranoside, o-(Hydroxymethyl)phenyl beta-D-glucopyranoside, Benzyl alcohol, o-hydroxy-, o-glucoside, UNII-4649620TBZ, AI3-19099, alpha-Hydroxy-o-tolyl beta-D-glucopyranoside, NSC 5751, EINECS 205-331-6, SPECTRUM1502255, B-D-Glucopyranoside, 2-(hydroxymethyl)phenyl, CHEBI:17814, beta-D-Glucopyranoside, 2-(hydroxymethyl)phenyl, D-()-Salicin, 4649620TBZ, SDCCGMLS-0066698.P001, NCGC00142605-01, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol, (2S,4S,5S,3R,6R)-6-(hydroxymethyl)-2-[2-(hydroxymethyl)phenoxy]-2H-3,4,5,6-tet rahydropyran-3,4,5-triol, SMR000112301, Salicin [USP], SR-05000001594, delta-Salicin, Spectrum_001230, Spectrum2_000756, Spectrum3_000948, Spectrum4_001058, Spectrum5_000971, bmse000315, D06BQU, Salicin from Plant Extract, Salicyl alcohol-b-glucoside, SCHEMBL24936, KBioGR_001356, KBioSS_001710, Saligenin-b-D-glucopyranoside, KSC914S4F, MLS000563050, MLS001306490, DivK1c_000030, S0625_SIGMA, SPBio_000772, AC1L97H8, CHEMBL462997, MEGxp0_000685, Salicin (Salicoside, Salicine), ACon1_000373, CTK8B4942, HMS500B12, KBio1_000030, KBio2_001710, KBio2_004278, KBio2_006846, KBio3_002016, BIK9020, MolPort-000-701-569, NGFMICBWJRZIBI-UJPOAAIJSA-N, NINDS_000030, HMS1921P08, HMS2092F14, HMS2268J11, Pharmakon1600-01502255, EBD45938, HY-N0149, Saligenin beta-delta-glucopyranoside, Saligenin-beta-delta-glucopyranoside, ZINC3847505, D-(-)-Salicin, analytical standard, Salicoside, Salicine, 138-52-3, ANW-46774, CCG-40332, CS0013, MFCD00006590, NSC758201, s2351, SBB012498, ZINC03847505, AKOS004907439, AC-8042, API0004125, CS-8027, D-(-)-Salicin, >=99% (GC), MCULE-4540152608, MCULE-8469382160, NSC-758201, RTR-031159, IDI1_000030, NCGC00142605-02, NCGC00142605-04, AJ-45866, AK-58886, CJ-10812, LS-71545, SC-11370, ST069327, SBI-0051746.P002, AX8002670, ST2414222, 2(hydroxymethyl)phenyl-beta-D-glucopyranoside, FT-0603347, N1880, S0003, A-8126, C01451, 2-(Hydroxymethyl)-phenyl-beta-D-glucopyranoside, 2-(hydroxymethyl)phenyl-O-beta-D-glucopyranoside, AB00052296_07, beta-D-Glucopyranoside, 2-(hydroxymethyl)phenyl-, 138S523, SR-05000001594-1, SR-05000001594-2, BRD-K64614248-001-02-4, BRD-K64614248-001-06-5, EAD32BE1-198E-432C-9F44-DC0DC9A3305B, Salicin, European Pharmacopoeia (EP) Reference Standard, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)-phenoxy)tetrahydro-2H-pyran-3,4,5-triol, 30370-90-2, SA0

ID: 1470

InChIKey: NGIVTUVVBWOTNT-UHFFFAOYSA-N
SMILES: CC1=CC(=NC(=N1)[N-]S(=O)(=O)C2=CC=C(C=C2)N)C.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16113
synonyms found at PubChem are:
Sulfamethazine sodium salt, 1981-58-4, SULFAMETHAZINE SODIUM, Sulfadimidine sodium, Sodium sulfamethazine, Sodium sulfametazine, Sodium sulfamethamide, Sodium sulfamezathine, Bovibol, Vesadin, Sodium sulfamethiazine, Sodium sulphamezathine, Sodium sulfadimidine, Sulfadimidin natrium, Sulmet, UNII-7Z13P9Q95C, Sulfamethazine and its sodium salt, EINECS 217-840-0, 7Z13P9Q95C, Sodium, (N(sup 1)-(4,6-dimethyl-2-pyrimidinyl)sulfanilamido)-, Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt, Sale sodico della 2-p-aminobenzensulfonamido-4,6-dimetil-pirimidina [Italian], C12H13N4NaO2S, sodium (4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide, Sulfanilamide, N(sup 1)-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt, Intradine (TN), Sulfadimidin (TN), Prestwick_1014, Sulphamethazine Sodium, MLS002153994, C12H13N4O2S.Na, CHEMBL1563050, MolPort-019-993-644, MolPort-028-599-773, HMS1570K12, HMS2097K12, HMS2236G08, HMS3374N06, HMS3714K12, BCP12146, MFCD00068333, Sale sodico della 2-p-aminobenzensulfonamido-4,6-dimetil-pirimidina, AKOS015913840, AKOS025311025, API0004267, CCG-220775, RP17636, KS-00000J20, NCGC00017038-01, AN-19784, AS-13841, O349, SMR001233328, CAS-1981-58-4, LS-147784, FT-0633950, S0583, D08539, J10415, A813963, SR-01000841213, J-524243, SR-01000841213-2, I14-43057, 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt, 4-amino-N-(4,6-dimethylpyrimidin-2-yl)-N-sodiobenzenesulfonamide, Sodium ((4-aminophenyl)sulfonyl)(4,6-dimethylpyrimidin-2-yl)amide, sodium (4-aminophenyl)sulfonyl-(4,6-dimethyl-2-pyrimidinyl)azanide, sodium (4-aminophenylsulfonyl)(4,6-dimethylpyrimidin-2-yl)amide, sodium,(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide

ID: 1471

InChIKey: NGSWKAQJJWESNS-ZZXKWVIFSA-N
SMILES: C1=CC(=CC=C1/C=C/C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JC Fulton" "M Mazur" "PA Sloane" "SM Rowe" "JP Clancy" "J Prasain" "S Barnes" "K Backer" "LC Pyle"

CID is 637542
synonyms found at PubChem are:
p-coumaric acid, 4-Hydroxycinnamic acid, p-Hydroxycinnamic acid, 501-98-4, 4-Coumaric acid, 7400-08-0, trans-4-Hydroxycinnamic acid, trans-p-Coumaric acid, 3-(4-hydroxyphenyl)acrylic acid, p-Cumaric acid, Para-Coumaric acid, Hydroxycinnamic acid, Naringeninic acid, p-Hydroxy-cinnamic acid, p-Hydroxyphenylacrylic acid, (E)-p-Coumaric acid, trans-p-Coumarinic acid, 4'-hydroxycinnamic acid, (E)-3-(4-Hydroxyphenyl)acrylic acid, Cinnamic acid, p-hydroxy-, (E)-p-Hydroxycinnamic acid, trans-p-Hydroxycinnamic acid, 3-(4-Hydroxyphenyl)-2-propenoic acid, (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid, trans-4-coumaric acid, 4-coumarate, 2-propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-, 4-Hydroxycinnamate, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, trans-p-Hydroxycinnamate, 4-hydroxy cinnamic acid, trans-4-hydroxycinnamate, UNII-IBS9D1EU3J, beta-(4-Hydroxyphenyl)acrylic acid, Cinnamic acid, p-hydroxy-, (E)-, (E)-3-(4-Hydroxyphenyl)-2-propenoic acid, Para coumaric acid, 3-(4-hydroxyphenyl)prop-2-enoic acid, (2E)-3-(4-hydroxyphenyl)acrylic acid, trans-p-Cumaric Acid, 4-Hydroxycinamic acid, EINECS 231-000-0, NSC 59260, IBS9D1EU3J, NSC 674321, (E)-4-hydroxycinnamic acid, BRN 2207381, BRN 2207383, CHEMBL66879, C9H8O3, (E)-3-(4-hydroxyphenyl)prop-2-enoic acid, CHEBI:32374, NGSWKAQJJWESNS-ZZXKWVIFSA-N, beta-[4-Hydroxyphenyl]acrylic acid, NSC674321, trans-p-coumarate, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)-, 3-(4-hydroxyphenyl)acrylate, (E)-3-[4-hydroxyphenyl]-2-propenoic acid, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (Z)-, (E)-3-(4-hydroxyphenyl)prop-2-enoate, CHEBI:36090, hydroxycinnamate, p-Coumaricacid, Para coumarate, 4-coumaric acid, (E)-isomer, p-coumaric-acid, Para-Coumarate, p-Cumarate, p-Hydroxycinnamate, 4qem, 4'-Hydroxycinnamate, 4-Hydroxy cinnamate, p-Coumaric acid,trans, PubChem8247, AC1LCUFZ, PubChem24323, 4f8j, p-Coumaric acid, trans, 4-Hydroxyphenylpropenoate, p-Caumaric acid dehydrogenation homopolymer, bmse000150, bmse000591, bmse010208, D0AU0M, b-[4-Hydroxyphenyl]acrylate, SCHEMBL39106, p-hydroxycinnamic acid (M4), 0-10-00-00297 (Beilstein Handbook Reference), 4-10-00-01005 (Beilstein Handbook Reference), MLS001066419, p-Hydroxycinnamic acid, trans, AKOS BAR-2479, beta-[4-Hydroxyphenyl]acrylate, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, homopolymer, AC1Q5T95, AC1Q71H0, BDBM4374, GTPL5787, P-HYDROXYL CINNAMIC ACID, RARECHEM BK HW 0163, COUMARIC ACID, TRANS-P-, DTXSID6064660, b-[4-Hydroxyphenyl]acrylic acid, TIMTEC-BB SBB007613, ZINC39811, ATTERCOP-CHM AT113965, MolPort-000-860-894, MolPort-004-288-351, HMS1409E10, 3-(4-Hydroxyphenyl)-2-propenoate, AKOS 221-47, BCP22803, HY-N2391, NSC59260, ZX-AT011614, Cinnamic acid, 4-hydroxy-, trans-, AN-287, BBL012226, LABOTEST-BB LT00452637, LABOTEST-BB LT03329617, MFCD00004399, NSC-59260, SBB007613, STL163567, .beta.-[4-Hydroxyphenyl]acrylic acid, AKOS000120685, AS03322, BCP9001042, CS-W020394, DB04066, LS30305, MP-2217, NSC-674321, RP09062, RP17402, RTR-017943, RTR-023948, OTAVA-BB 7020400347, p-Coumaric acid, >=98.0% (HPLC), NCGC00246974-01, 4CN-0926, 50940-26-6, AC-10318, AJ-08911, AS-12000, BP-13278, BR-26304, KB-72564, LS-54111, LS-54112, SC-25929, SC-65982, SMR000112201, ST093691, trans-p-Coumaric acid, analytical standard, AX8022446, ST2402517, TC-164240, TL8005115, TR-017943, TR-023948, AM20050138, N1817, ST24022578, (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid, C00811, (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid #, (E)-3-(4-HYDROXY-PHENYL)-ACRYLIC ACID, 400H080, AE-562/40414679, I01-9546, I01-9648, I04-0102, Q-100560, W-104438, 0C1BFF2D-2CF7-4FC1-9F76-3268C2C7F783, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI), F2191-0188, p-Coumaric acid, primary pharmaceutical reference standard, InChI=1/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3

ID: 1472

InChIKey: NGVLSOWJSUUYDE-UHFFFAOYSA-N
SMILES: C1CCN(C(C1)CN2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11315337
synonyms found at PubChem are:
BRL 52537 hydrochloride, 130497-33-5, 2-(3,4-Dichlorophenyl)-1-(2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone hydrochloride, 112282-24-3, BRL 52537, (+/-)-1-(3,4-Dichlorophenyl)acetyl-2-(1-pyrrolidinyl)methylpiperidine hydrochloride, 2-(3,4-DICHLOROPHENYL)-1-(2-(PYRROLIDIN-1-YLMETHYL)PIPERIDIN-1-YL)ETHANONE HCL, SR-01000076141, EU-0101141, D03QZJ, D04YNW, BRL-52537 hydrochloride, Brl 52537 HCl, MLS002153457, SCHEMBL8435659, CHEMBL1256835, CTK8C4721, KS-00000FTT, DTXSID00462129, MolPort-003-940-484, BCP21081, EBD29079, Tox21_501141, ABP001017, ANW-72902, BN0592, AKOS015910291, API0009081, DS-1689, LP01141, MP-1898, KS-000024N2, NCGC00094407-01, NCGC00261826-01, 4CA-0320, AK-57392, BR-57392, CC-16057, QC-10222, SMR000326905, AB0069170, AX8118701, KB-221382, RT-011816, ST24027492, B 5559, J-005817, SR-01000076141-1, SR-01000076141-3, I14-40265, Pleiotropic pathway modulator (oral, cancer), Celgene, Pleiotropic pathway modifiers (inflammatory disease), Celgene, (+/-)-1-(3,4-Dichlorophenyl)acetyl-2-( 1-pyrrolidinyl)methylpiperidine hydrochloride, 2-(3,4-dichlorophenyl)-1-(2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethan-1-one hydrochloride, 2-(3,4-dichlorophenyl)-1-{2-[(pyrrolidin-1-yl)methyl]piperidin-1-yl}ethan-1-one hydrochloride

ID: 1473

InChIKey: NHTGHBARYWONDQ-UHFFFAOYSA-N
SMILES: CC(CC1=CC=C(C=C1)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3125
synonyms found at PubChem are:
DL-alpha-Methyltyrosine, 658-48-0, Racemetirosine, 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid, DL-alpha-Methyl-p-tyrosine, Racemetirosina, Racemetirosinum, Racemetirosine [INN], alpha-Methyl-dl-tyrosine, Racemetirosinum [INN-Latin], Racemetirosina [INN-Spanish], 620-30-4, (+-)-alpha-Methyl-DL-tyrosine, alpha-Methyl-p-tyrosine, alpha-MPT, Tyrosine, .alpha.-methyl-, Metyrosine, DL-, alpha-Methylparatyrosine, DL-, 2-P-HYDROXYPHENYLMETHYL-DL-ALANINE, .alpha.-Methyltyrosine, Tyrosine, alpha-methyl-, alpha-Methyltyrosine, (D,L)-Isomer, EINECS 210-635-7, EINECS 211-523-0, H 9/88, alpha-Methyl-D,L-tyrosine, BRN 2938704, AI3-62542, (R,S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropionsaeure, alpha-Methyltyrosine, (L)-Isomer, M-5185, 4-Hydroxy-alpha-methylphenylalanine, alpha-Methyltyrosine, (+,-)-Isomer, C10H13NO3, DL-2-Methyl-3-(4-hydroxyphenyl)alanine, alpha-Methyl-para-tyrosine, Metirosine (INN), Metyrosine (USP), Demser (TN), a-methyl-L-p-tyrosine, A-METHYL-DL-P-TYROSINE, Metirosinum [INN-Latin], Metirosina [INN-Spanish], 2-Methyltyrosine, ( -)-alpha-Methyl-DL-tyrosine, Metyrosine[USAN], L-2-Methyl-3-(4-hydroxy-phenyl)alanine, M 8131, D,L-alpha-methyltyrosine, dl-.alpha.-Methyltyrosine, .alpha.-Methylparatyrosine, .alpha.-Methyl-p-tyrosine, D0B3QM, L 588357-0, .alpha.-Methyl-dl-tyrosine, DL-Tyrosine, alpha-methyl-, Lopac0_000001, SCHEMBL61871, (-)-(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropionsaeure, 4-14-00-02453 (Beilstein Handbook Reference), MLS000028638, dl-.alpha.-Methyl-p-tyrosine, (-)-alpha-Methyl-DL-tyrosine, 2-Amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid, AC1L1F85, AC1Q2B51, GTPL5094, CHEMBL1330596, alpha-Methyl-DL-tyrosine, 98%, CTK8G3945, KS-00000JLO, MolPort-001-792-045, NHTGHBARYWONDQ-UHFFFAOYSA-N, HMS3260A03, ACT10012, CS-D0593, Tox21_500001, 6633AH, MFCD00004187, SBB015064, STK272180, AKOS003391424, AKOS022063174, CCG-204097, DS-6468, FCH1115083, LP00001, MCULE-1700935161, (.+/-.)-.alpha.-Methyl-DL-tyrosine, NCGC00015701-03, NCGC00015701-04, NCGC00015701-05, NCGC00093528-01, NCGC00093528-02, NCGC00260686-01, AK129847, alpha-Methyl-DL-tyrosine, >=95% (NT), AN-47132, CPD000059140, SAM001246859, SMR000059140, ST075173, LS-158317, ST2404111, EU-0100001, FT-0632594, 672M866, SR-01000075605, SR-01000075607, SR-01000075605-1, SR-01000075607-1, 2-amino-3-(4-hydroxyphenyl)-2-methyl-propanoic acid, I14-53963, (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoicacid, 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide

ID: 1474

InChIKey: NHUHCSRWZMLRLA-UHFFFAOYSA-N
SMILES: CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5344
synonyms found at PubChem are:
sulfisoxazole, Sulfafurazole, 127-69-5, Sulphafurazole, Sulfisoxazol, Sulfafurazol, Sulfaisoxazole, Sulfofurazole, Sulfisoxasole, Sulphaisoxazole, Sulfadimethylisoxazole, Gantrisin, Alphazole, Amidoxal, Sulfalar, Sulfoxol, Sulfisoxazole dialamine, Sulphafurazolum, Renosulfan, Sulfasoxazole, Sulfisonazole, Accuzole, Soxomide, Sulfazin, Sulfizin, Sulsoxin, Sosol, Roxosul tablets, Sulphafurazol, Sulphisoxazol, Sulphofurazole, Chemouag, Cosoxazole, Gantrisona, Gantrosan, Isoxamin, Neazolin, Neoxazol, Sulfagan, Sulfasol, Uritrisin, Entusil, Entusul, Pancid, Soxisol, Stansin, Sulbio, Thiasin, Unisulf, Norilgan-S, Tl-azole, V-Sul, SK-Soxazole, Sulfafurazolum, Sulphadimethylisoxazole, Dorsulfan, Gantrisine, Novazolo, Novosaxazole, Saxosozine, Sodizole, Soxamide, Soxazole, Soxitabs, Sulfapolar, Sulfisin, Sulfizol, Sulfizole, Urisoxin, Roxosul, Urogan, Vagilia, Azo Gantrisin, Dorsulfan warthausen, Koro-sulf, SOXO, Sulfisoxazolum, Sulphisoxazole, 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide, J-Sul, 3,4-Dimethyl-5-sulfonamidoisoxazole, 3,4-Dimethyl-5-sulfanilamidoisoxazole, 5-Sulfanilamido-3,4-dimethylisoxazole, Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-, G-sox, 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, Sulfazin (VAN), Azosulfizin, Solfafurazolo, Sulfasoxizole, Sulphafuraz, 3,4-Dimethyl-5-sulphonamidoisoxazole, Astrazolo, Bactesulf, Barazae, Neoxazoi, Resoxol, Roxoxol, Sulfagen, Suloxsol, 3,4-Dimethylisoxazole-5-sulfanilamide, Ganda, 3,4-Dimethyl-5-sulphanilamidoisoxazole, 3,4-Dimethylisoxazole-5-sulphanilamide, Solfafurazolo [DCIT], 5-Sulphanilamido-3,4-dimethyl-isoxazole, NCI-C50022, Sulfafurazolum [INN-Latin], ERYZOLE, SULFISOXAZOLE DIOLAMINE, 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole, 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole, NU 445, Sulfisoxazole [USAN], 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole, Pediazole, N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide, Sulfafuraz ole, U.S.-67, Gantrisin (TN), 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide, CCRIS 568, 5-Sulfanilamido-3,4-dimethyl-isoxazole, HSDB 797, Sulfafurazole (INN), N(Sup1)-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, UNII-740T4C525W, C11H13N3O3S, CHEBI:102484, component of Azo-Sulfizin, EINECS 204-858-9, NSC 13120, component of Azo Gantrisin, CHEMBL453, NSC 683536, BRN 0263871, N(sup 1)-(3,4-Dimethyl-5-isoxazolyl)sulphanilamide, AI3-24003, NHUHCSRWZMLRLA-UHFFFAOYSA-N, US-67, Component of Azo Gantrisin Accuzole, NSC13120, 3,4-Dimethylisoxale-5-sulfanilamide, N(sup 1)-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, NSC683536, Sulfafurazole [INN], 740T4C525W, 3,4-dimethylisoaxazole-5-sulfanilimide, NCGC00016384-03, NCGC00016384-10, 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide, 4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide, CAS-127-69-5, DSSTox_CID_1292, N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide, DSSTox_RID_76064, DSSTox_GSID_21292, N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide, Sulfanilamide, N1-(3,4-dimethyl-5-isoxazolyl)-, 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisooxale, Sulfanilamide, N(sup 1)-(3,4-dimethyl-5-isoxazolyl)-, [(4-aminophenyl)sulfonyl](3,4-dimethylisoxazol-5-yl)amine, WLN: T5NOJ CMSWR DZ& D1 E1, Sulfanilamide,4-dimethyl-5-isoxazolyl)-, SMR000037657, Sulfafurazole(SIZ), Benzenesulfonamide,4-dimethyl-5-isoxazolyl)-, SR-01000003085, Sulfisoxazole [USP:JAN], Gantrizin, Sulfisoxazole-Carc, Prestwick_726, Sulfisoxazole - Carc, Spectrum_001024, Tocris-0731, Prestwick0_000334, Prestwick1_000334, Prestwick2_000334, Prestwick3_000334, Spectrum2_001325, Spectrum3_001728, Spectrum4_000349, Spectrum5_001222, Azo-Sulfizin (Salt/Mix), Azo Gantrisin (Salt/Mix), D09TBD, Epitope ID:122240, Sulfisoxazole (JP15/USP), Sulfisoxazole (JP17/USP), Sulfisoxazole, >=99.0%, Oprea1_680668, Oprea1_828173, SCHEMBL23467, BSPBio_000367, BSPBio_003376, KBioGR_000757, KBioSS_001504, 4-27-00-04747 (Beilstein Handbook Reference), MLS000028495, MLS000037737, MLS000563718, BIDD:GT0322, DivK1c_000579, SPECTRUM1500555, SPBio_001449, SPBio_002288, AC1L1K55, BPBio1_000405, DTXSID6021292, CTK7D7932, HMS501M21, KBio1_000579, KBio2_001504, KBio2_004072, KBio2_006640, KBio3_002596, Sulfafurazole;Gantrisin Pediatric, MolPort-000-422-016, NINDS_000579, HMS1569C09, HMS2092K13, HMS2096C09, HMS2233G23, HMS3259C06, HMS3266N17, HMS3374K11, HMS3655B03, HMS3713C09, Pharmakon1600-01500555, ALBB-014131, HY-B0323, NSC33807, NSC38588, ZX-AH011786, Tox21_110409, Tox21_112958, Tox21_202265, Tox21_302851, 6155-81-3 (mono-lithium salt), BDBM50034452, CCG-39263, LS-713, MFCD00003150, NSC-13120, NSC-33807, NSC-38588, NSC757343, s1916, SBB007602, STK400452, ZINC96006009, AKOS000119074, AKOS000310021, Tox21_110409_1, AC-1941, CS-2364, DB00263, MCULE-3522661051, NC00536, NSC-683536, NSC-757343, ABA-9370315, IDI1_000579, 2200-44-4 (mono-hydrochloride salt), NCGC00016384-01, NCGC00016384-02, NCGC00016384-04, NCGC00016384-05, NCGC00016384-06, NCGC00016384-07, NCGC00016384-08, NCGC00016384-09, NCGC00016384-11, NCGC00016384-12, NCGC00016384-14, NCGC00016384-15, NCGC00023116-02, NCGC00023116-05, NCGC00023116-06, NCGC00023116-07, NCGC00023116-08, NCGC00256605-01, NCGC00259814-01, AN-14478, BAS 00531889, BC214921, CPD000037657, R536, SAM002554929, SC-15955, ST059445, SBI-0051529.P003, AB2000373, UPCMLD00X127-69-5:001, AB00052104, BB 0259593, FT-0631743, U0098, C07318, D00450, J10241, Y-9398, AB00052104-14, AB00052104_15, AB00052104_16, Sulfisoxazole, VETRANAL(TM), analytical standard, 5-(4-Aminophenylsulphonamido)-3,4-dimethylisoxazole, J-005528, SR-01000003085-2, SR-01000003085-5, SR-01000003085-6, 5-(4-aminop henylsulfonamido)-3,4-dimethylisoxazole, 5-(p-Aminobenzenesulphonamide)-3,4-dimethylisoxazole, BRD-K50859149-001-05-4, BRD-K50859149-001-10-4, I01-15830, N(sup 1)-(3,4-dimethyl-5-isoxazolyl)-sulfanilamide, Sulfanilamide, N(sup1)-(3,4-dimethyl-5-isoxazolyl)-, Sulfanilamide, N.sup1.-(3,4-dimethyl-5-isoxazolyl)-, F0848-0391, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzene-sulfonamide, 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide #, 4-amino-N-(3,4-dimethylisoxazol-5-yl)-benzenesulfonamide, 4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Sulfafurazole, European Pharmacopoeia (EP) Reference Standard, Sulfisoxazole, United States Pharmacopeia (USP) Reference Standard, 1021066-10-3, 207522-06-3, InChI=1/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H

ID: 1475

InChIKey: NIBOMXUDFLRHRV-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 210172
synonyms found at PubChem are:
21102-95-4, BMY 7378 dihydrochloride, BMY 7378, 8-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, UNII-KC07KV8T5O, KC07KV8T5O, CHEMBL543741, 1,1-Cyclopentanediacetimide, N-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-, dihydrochloride, azaspiro[4.5]decane-7,9-dione dihydrochloride, N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride, 8-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, SR-01000075542, 21102-94-3, 8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, BMY7378 dihydrochloride, AC1L4O5A, BMY-7378 dihydrochloride, BMY7378 HCl, SCHEMBL987183, C22H33Cl2N3O3, AC1Q3B30, CTK4E5880, KS-00002WWY, AOB6861, DTXSID10175334, MolPort-003-940-399, BCP02522, KS-00000XL4, Tox21_500206, ABP000464, ANW-53719, BN0115, MFCD00153771, s2691, AKOS015999114, API0008484, CCG-221510, LP00206, MG-0114, BMY7378,BMY-7378 dihydrochloride/, NCGC00093679-01, NCGC00260891-01, 4CA-0309, AC-26868, BC638830, KB-48110, LS-57940, SC-94621, AX8228522, ST2406587, TX-012209, B-134, EU-0100206, FT-0710084, X7600, 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl-, BMY 7378 dihydrochloride, >=98% (HPLC), solid, J-013847, SR-01000075542-1, SR-01000075542-3, BMY7378;BMY-7378;21102-95-4, 8-(2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL)-8-AZASPIRO(4,5)DECANE-7,9-DIONE DIHYDROCHLORIDE, 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride, 8-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride, 8-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dionedihydrochloride, 8-Azaspiro[4.5]decane-7,9-dione, 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-, hydrochloride, AKOS026750639

ID: 1476

InChIKey: NIGWMJHCCYYCSF-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CC(C(=O)O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4652
synonyms found at PubChem are:
Fenclonine, 7424-00-2, 4-Chloro-DL-phenylalanine, DL-4-Chlorophenylalanine, 2-amino-3-(4-chlorophenyl)propanoic acid, p-chlorophenylalanine, 4-Chlorophenylalanine, Fenchlonine, DL-p-Chlorophenylalanine, Fenclonin, Phenylalanine, 4-chloro-, DL-PCPA, C-Pal, para-Chlorophenylalanine, DL-3-(p-Chlorophenyl)alanine, p-Chloro-DL-phenylalanine, p-Clorophenylalanine, DL-PHE(4-CL)-OH, 2-Amino-3-(4-chlorophenyl)propionic acid, DL-Phenylalanine, 4-chloro-, H-DL-PHE(4-CL)-OH, Fenclonine [USAN:INN], Fencloninum [INN-Latin], 4-Chloro-3-phenylalanine, Fenclonina [INN-Spanish], CP 10,188, (+-)-p-Chlorphenylalanine, NSC 77370, Alanine, 3-(4-chlorophenyl)-, DL-, H-P-CHLORO-DL-PHE-OH, 3-(p-Chlorophenyl)-DL-alanine, EINECS 231-051-9, ALANINE, 3-(p-CHLOROPHENYL)-, BRN 2805758, CP-10188, AI3-62057, CP-10,188, ALANINE, 3-(p-CHLOROPHENYL)-, DL-, NIGWMJHCCYYCSF-UHFFFAOYSA-N, NCGC00015255-04, CP 10188, 1991-78-2, DSSTox_CID_25139, DSSTox_RID_80697, DSSTox_GSID_45139, (RS)-2-Amino-3-(4-chloro-phenyl)-propionic acid;H-4-Chloro-DL-Phe-OH;Fenclonine;PCPA, CAS-7424-00-2, SR-01000075543, 4-Chloro-3-phenyl-L-alanine, HSDB 7747, Fenclonine (PCPA), Parachlorophenylalanine, p-CPA, Spectrum_001188, 4-Chlorophenylalanine #, AC1L1IND, AC1Q3NPJ, Spectrum2_001479, Spectrum3_001766, Spectrum4_000863, Spectrum5_001312, (y)-p-Chlorophenylalanine, ACMC-1BV3F, (?)-p-Chlorophenylalanine, D0F2GG, Lopac0_000286, SCHEMBL26382, BSPBio_003231, KBioGR_001525, KBioSS_001668, (+/-)-p-Chlorophenylalanine, DivK1c_000873, SPECTRUM1502162, SPBio_001437, (A+/-)-p-Chlorophenylalanine, H-4-CHLORO-DL-PHE-OH, (.+-.)-p-Chlorophenylalanine, GTPL5240, (.+/-.)-p-Chlorphenylalanine, CHEMBL1256351, DTXSID4045139, (.+/-.)-p-Chlorophenylalanine, BDBM82270, CTK3J5078, HMS502L15, KBio1_000873, KBio2_001668, KBio2_004236, KBio2_006804, KBio3_002731, KS-00000AHA, AOB5290, 4-Chloro-dl-.beta.-phenylalanine, CHEBI:110187, MolPort-001-794-625, NINDS_000873, 51274-82-9 (hydrochloride), HMS3260J14, AC1Q5097, HY-B1368, NSC77370, Tox21_110114, Tox21_500286, 1535AC, ANW-36452, BBL027391, CCG-39197, MFCD00002601, NSC-77370, s4586, SBB003551, STK735561, AKOS000183864, AKOS016050371, Tox21_110114_1, AB00241, AC-9879, CS-4900, LP00286, MCULE-2078281838, RTR-033368, VC30853, VZ28815, VZ28817, IDI1_000873, alpha-Amino-4-chlorobenzenepropionic acid, NCGC00015255-03, NCGC00015255-05, NCGC00015255-06, NCGC00015255-07, NCGC00015255-08, NCGC00024889-02, NCGC00024889-03, NCGC00024889-04, NCGC00024889-05, NCGC00260971-01, RAC-BETA-(4-CHLOROPHENYL)ALANINE, AN-10564, AN-10565, AS-49808, LS-15962, LS-15963, SC-10559, CAS_7424-00-2, DB-013514, ST2416340, TR-033368, AM20060839, EU-0100286, FT-0625406, ( inverted question mark)-p-Chlorophenylalanine, C 6506, D04143, AB00052283-03, AB00052283_04, 424P002, I01-3147, I01-3154, I01-7445, J-300388, SR-01000075543-1, SR-01000075543-3, W-204245, BRD-A81615860-001-02-9, DL-2-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID, F2147-6563, (RS)-2-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID, A3769/0159907, RAC-ALPHA-AMINO-BETA-(4-CHLOROPHENYL)PROPIONIC ACID

ID: 1477

InChIKey: NILQLFBWTXNUOE-UHFFFAOYSA-N
SMILES: C1CCC(C1)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2901
synonyms found at PubChem are:
cycloleucine, 1-Aminocyclopentanecarboxylic acid, 52-52-8, 1-Aminocyclopentane-1-carboxylic acid, Cycloleucin, 1-Amino-1-cyclopentanecarboxylic acid, 1-Amino-1-carboxycyclopentane, 1-Amino-cyclopentanecarboxylic acid, Cyclopentanecarboxylic acid, 1-amino-, CYCLO-LEUCINE, NSC 1026, CB 1639, X 201, UNII-0TQU7668EI, 1-Aminocyclopentanecarboxylate, HSDB 5195, WR 14,997, NSC1026, 1-amino cyclopentane carboxylic acid, EINECS 200-144-6, BRN 0636626, AI3-26442, aminocyclopentanecarboxylic acid, Cyclopentanecarboxylic acid, 1-amino-, L-, 0TQU7668EI, CHEMBL295830, CHEBI:40547, Cycloleucine1-Amino-cyclopentanecarboxylic acid, 1-amino-1-Cyclopentanecarboxylate, NILQLFBWTXNUOE-UHFFFAOYSA-N, 1-Aminocyclopentane carboxylic acid, Amino-1-cyclopentanecarboxylic acid, 1-amino-1-cyclopentane carboxylic acid, WR 14997, AC1OCG3T, 1-aminocyclopentane-1-carboxylate, AC5, 1-ammonio-1-cyclopentanecarboxylate, A829129, Leucine, Cyclo-, Cycloleucine, 97%, 1-aminocyclopentane(14c)carboxylic acid, (2E)-Decenoyl-ACP, PubChem13875, Spectrum_001268, 1y1m, AC1Q1HCY, Spectrum2_000931, Spectrum3_001514, Spectrum4_000340, Spectrum5_001136, Biomol-NT_000201, D0P0GT, NCIMech_000677, WLN: L5TJ AZ AVQ, AC1L1EQ8, AC1Q50GB, SCHEMBL8495, BSPBio_003187, KBioGR_000719, KBioSS_001748, 4-14-00-00974 (Beilstein Handbook Reference), KSC270A3J, DivK1c_000723, SPECTRUM1502128, SPBio_000862, 1-amino-Cyclopentanecarboxylate, ACMC-209l02, BPBio1_001084, ZINC1234, Cyclopentanecarboxylic acid, L-, Acid, aminocyclopentanecarboxylic, DTXSID5024475, CTK1H0034, HMS502E05, KBio1_000723, KBio2_001748, KBio2_004316, KBio2_006884, KBio3_002687, NILQLFBWTXNUOE-UHFFFAOYSA-, 1 Aminocyclopentanecarboxylic acid, MolPort-000-000-295, NINDS_000723, HMS1921L08, Acid, 1-aminocyclopentanecarboxylic, ACN-S002879, ACT04362, CS-B0093, KS-000000OZ, NSC-1026, 1-amino-cyclopentane carboxylic acid, Cyclopentanecarboxylicacid, 1-amino-, ANW-31488, BBL020454, BDBM50070638, CC-906, CCG-35835, FD1031, LS-173, MFCD00001381, SBB004230, STK133034, ZINC00001234, AKOS000183252, AC-2700, DB04620, LS00115, MCULE-6366286422, RP19853, RTC-066264, TRA0014299, IDI1_000723, NCGC00094966-01, NCGC00094966-02, NCGC00094966-03, NCGC00094966-04, NCGC00163268-01, NCGC00178218-01, AJ-07980, AN-13723, AS-11677, BR-29341, KB-11135, NCI60_000070, SC-11054, SY002601, Cycloleucine1-amino-cyclopentanecarboxylate, AB0000970, AB1001403, CYCLOPENTANECARBOXYLIC ACID, L-AMINO, DB-031284, ST2408631, 4CH-013110, AM20100281, FT-0082968, FT-0607341, ST45026863, 1-Aminocyclopentanecarboxylic acid, 97% 1g, EN300-39470, C03969, 001C381, I04-0452, J-504199, J-802019, F8881-4536, 3DD7E30B-2149-43D9-A44B-7A59D546A28B, InChI=1/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9), 15313-85-6, 1-azaniumylcyclopentane-1-carboxylate, CJ-00036, ZB000283

ID: 1478

InChIKey: NIWCFXFECXNXGD-PFEQFJNWSA-N
SMILES: CN1CCC2=CC=CC3=C2[C@H]1CC4=C3C(=C(C=C4)OC)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 22872
synonyms found at PubChem are:
EINECS 228-947-7, 10-Methoxy-6a-beta-aporphin-11-ol hydrochloride, 6a-beta-APORPHIN-11-OL, 10-METHOXY-, MONOHYDROCHLORIDE, AC1L2L8O, LS-21498, 6abeta-Aporphin-11-ol, 10-methoxy-, monohydrochloride, 4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride, (R)-, R(-)-Apocodeine hydrochloride, NSC 305238, (R-(-)-Apocodeine Hydrochloride, 6377-14-6, Apocodeine hydrochloride, R(-)-10-Methoxy-11-hydroxyaporphine hydrochloride, R(-)-Apocodeine HCl, EU-0100425, R()-Apocodeine hydrochloride, MLS000859992, CHEMBL1256735, Tox21_500425, CCG-221729, LP00425, NCGC00261110-01, SMR000326851, D-003, 10-Methoxy-6a|A-aporphin-11-ol Monohydrochloride, SR-01000075363, SR-01000075363-1, 6abeta-Aporphin-11-ol, 10-methoxy-, monohydrochloride (8CI), (6aR)-5,6,6a,7-Tetrahydro-10-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol Hydrochloride, 4H-Dibenzo(de,g)quinolin-11-ol, 5,6,6a,7-tetrahydro-10-methoxy-6-methyl-, hydrochloride, (R)- (9CI)

ID: 1479

InChIKey: NJBFOOCLYDNZJN-UHFFFAOYSA-N
SMILES: C1CN(CCN1C(=O)CCBr)C(=O)CCBr

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4842
synonyms found at PubChem are:
pipobroman, Vercyte, 54-91-1, Amedel, 1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one), Pipobromanum, A-8103, 1,4-Bis(3-bromopropionyl)piperazine, Piperazine, 1,4-bis(3-bromo-1-oxopropyl)-, N,N-Bis-(3-bromopropionyl)-piperazine, Pipobromanum [INN-Latin], A 1803, NSC-25154, Pipobroman [USAN:INN], Piperazine, 1,4-bis(3-bromopropionyl)-, UNII-6Q99RDT97R, 1,4-Bis(3-bromopropanoyl)piperazine, N,N'-Bis(3-bromopropionyl)piperazine, C10H16Br2N2O2, CCRIS 2753, HSDB 3249, VERCYTE (TN), 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one, NSC 25154, BRN 0749866, Pipobroman (JAN/USAN/INN), AI3-50113, 6Q99RDT97R, CHEBI:8242, NSC25154, NCGC00095048-01, DSSTox_CID_3485, DSSTox_RID_77048, DSSTox_GSID_23485, CAS-54-91-1, SR-05000001858, Pipobroman [USAN:USP:INN], Vercite, Vercyte, Spectrum_001727, Spectrum2_000912, Spectrum3_001047, Spectrum5_001135, D03FNJ, AC1L1J2T, SCHEMBL4889, CHEMBL1585, BSPBio_002574, KBioSS_002207, DivK1c_000799, SPECTRUM1503393, SPBio_000784, GTPL7271, DTXSID7023485, CTK5I9947, HMS502H21, KBio1_000799, KBio2_002207, KBio2_004775, KBio2_007343, KBio3_001794, KS-00000GXJ, MolPort-003-665-507, NINDS_000799, NJBFOOCLYDNZJN-UHFFFAOYSA-N, HMS1922C10, HMS2093E11, Pharmakon1600-01503393, WLN: T6N DNTJ AV2E DV2E, ZINC1530753, 1,4-di(3-bromopropionyl)piperazine, Tox21_111402, 7981AB, CCG-39748, NSC758461, Piperazine,4-bis(3-bromopropionyl)-, 1, 4-Bis(3-bromopropionyl)piperazine, AKOS016010321, Tox21_111402_1, API0005280, CS-5085, DB00236, DS-4654, NSC-758461, 1,4-Bis(3-bromopropanoyl)piperazine #, IDI1_000799, NCGC00095048-02, NCGC00095048-03, NCGC00095048-04, NCGC00095048-06, AK116464, HY-16398, NCI60_002008, Piperazine,4-bis(3-bromo-1-oxopropyl)-, AX8148270, LS-110402, 4CH-024671, ST24036545, A 8103, C07362, D00467, AB00052352-02, AB00052352_03, 1,1'-piperazine-1,4-diylbis(3-bromopropan-1-one), SR-05000001858-1, SR-05000001858-2

ID: 1480

InChIKey: NJLRKAMQPVVOIU-IDLGWYNRSA-N
SMILES: CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5[C@@]6([C@@H](C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5[C@@]6([C@@H](C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)C(=C3C)CCC(=O)OC)C=C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 11980904
synonyms found at PubChem are:
SCHEMBL6218, Verteporfin (JAN/USAN/INN), SCHEMBL1230373, Verteporfin, >=94% (HPLC), MolPort-046-033-535, HY-B0146, AKOS015896072, CS-1950, D01162, I06-2039, Verteporfin, United States Pharmacopeia (USP) Reference Standard

ID: 1481

InChIKey: NJNKPVPFGLGHPA-UHFFFAOYSA-N
SMILES: C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 5353940
synonyms found at PubChem are:
SB 202190, 152121-30-7, SB202190, SB-202190, FHPI, UNII-PVX798P8GI, CHEBI:79090, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole, SB202190 (FHPI), 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole, PVX798P8GI, SB 202190, Immobilized, C20H14FN3O, InSolution™ SB 202190, Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-, IN1110, IN1113, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole, 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol, 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol, 4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol, 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol, 4-(5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl)phenol, SMR001230795, Oxindole 94, Kinome_3708, Tocris-1264, AC1NS4QB, BiomolKI_000051, Lopac-S-7067, biotinylated SB202190, BiomolKI2_000057, D0EF7D, D0VC0I, Lopac0_000173, BMK1-F3, BSPBio_001106, KBioGR_000446, KBioSS_000446, MLS002153419, MLS006010258, SCHEMBL158854, CHEMBL278041, FHPI and SB 202190, GTPL4307, SCHEMBL1230814, DTXSID7041120, BDBM13531, CHEBI:92952, KBio2_000446, KBio2_003014, KBio2_005582, KBio3_000831, KBio3_000832, AOB2557, EX-A313, SYN1073, 4o77, MolPort-003-959-586, MolPort-028-617-504, NJNKPVPFGLGHPA-UHFFFAOYSA-N, ZX-AFC001670, Bio1_000479, Bio1_000968, Bio1_001457, Bio2_000393, Bio2_000873, HMS1362H07, HMS1792H07, HMS1990H07, HMS2235B15, HMS3229M22, HMS3244I13, HMS3244I14, HMS3244J13, HMS3260D07, HMS3267J19, HMS3371G22, HMS3403H07, HMS3654O15, BCP00675, Tox21_500173, ABP000229, BDBM50044784, BS0317, CF-035, GK2422, MFCD00941964, RS0054, s1077, ZINC14951176, ZINC89221712, AKOS005146403, AKOS026750414, ACN-053035, AN-5323, CCG-100655, CCG-204268, CS-0141, LP00173, QC-9800, IDI1_002148, SMP2_000191, NCGC00015962-01, NCGC00015962-02, NCGC00015962-03, NCGC00015962-04, NCGC00015962-05, NCGC00015962-06, NCGC00015962-07, NCGC00015962-08, NCGC00015962-09, NCGC00015962-10, NCGC00025089-01, NCGC00025089-02, NCGC00025089-03, NCGC00025089-04, NCGC00025089-05, NCGC00025089-06, NCGC00260858-01, AS-16228, BC280328, HY-10295, KB-80489, SC-27980, AJ-128486, LS-186973, LS-187615, EU-0100173, FT-0743934, X7402, A15255, S 7067, SB 202190, >=98% (HPLC), SB 202190/SB-202190, 121S307, SR-01000075720, SR-01000597393, J-513574, J-690315, SR-01000075720-1, SR-01000597393-1, BRD-K54330070-001-05-5, BRD-K54330070-001-07-1, 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-2H-imidazol, A3839/0163020, SB202190, 152121-30-7, 4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]phenol, 4-[4-(4-Fluorphenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol, FHPI|||4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one, 194615-33-3, 2RE, 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,3-dihydro-2H-imidazol-2-ylidene)cyclohexa-2,5-dien-1-one, 4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one, 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one

ID: 1482

InChIKey: NJTUORMLOPXPBY-UHFFFAOYSA-N
SMILES: CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 176406
synonyms found at PubChem are:
ZM 39923 hydrochloride, jak3 inhibitor iv, 1021868-92-7, 58753-54-1, ZM 39923 HCl, ZM 39923, ZM39923 (hydrochloride), ZM39923 hydrochloride, CHEMBL538798, 3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one hydrochloride, 3-BENZYLISOPROPYLAMINO-1-NAPHTHALEN-2-YL-PROPAN-1-ONE HYDROCHLORIDE, IN1285, 2-Naphthyl-(N-isopropyl,N-benzyl)-beta-aminoethylketone, HCI, 3-(N-Benzyl-N-isopropyl)amino-1-(naphthalen-2-yl)propan-1-one hydrochloride, SR-01000075509, C23H25NO.ClH, MLS002153398, ZM39923 HCl, AC1L423H, ZM-39923 HCl, SCHEMBL17318371, CTK8G0412, KS-00000HAI, DTXSID70207488, MolPort-003-960-231, BCP15841, Tox21_500844, 2819AH, IN2287, s8004, AKOS024456551, CCG-206763, CS-4951, LP00844, NCGC00094173-01, NCGC00261529-01, AC-30261, AN-25406, BC600529, HY-12589, SMR001230777, ZM 39923 hydrochloride, >98% (HPLC), EU-0100844, Z 4626, SR-01000075509-1, SR-01000075509-3, 2-Naphthyl-(N-isopropyl,N-benzyl)-b-aminoethylketone, HCI, 3-[benzyl(isopropyl)amino]-1-(2-naphthyl)propan-1-one hydrochloride, 3-[benzyl(propan-2-yl)amino]-1-(naphthalen-2-yl)propan-1-one hydrochloride, 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride, 3-(N-Benzyl-N-isopropyl)amino-1-(naphthalen-2-yl)propan-1-one, hydrochloride, 3-[(1-Methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone hydrochloride, SCHEMBL16211659, AKOS026750498

ID: 1483

InChIKey: NJXWZWXCHBNOOG-UHFFFAOYSA-N
SMILES: CC(C1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 26154
synonyms found at PubChem are:
Difmecor, Sensit, EINECS 237-121-5, HK 137, Fendiline HCl, (3,3-Diphenylpropyl)(1-phenylethyl)ammonium chloride, N-(1-Phenylethyl)-3,3-diphenylpropylamine hydrochloride, gamma-Phenyl-N-(1-phenylethyl)benzenepropanamine hydrochloride, N-(3,3-Diphenylpropyl)-alpha-methylbenzylamine hydrochloride, Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-, hydrochloride, BENZYLAMINE, N-(3,3-DIPHENYLPROPYL)-alpha-METHYL-, HYDROCHLORIDE, AC1L1AJ6, C23H25N.HCl, AKOS015916630, LS-43352, 3,3-diphenylpropyl(1-phenylethyl)azanium chloride, I14-49495, AC1LCWEG, 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine; hydron; chloride, Fendiline hydrochloride, 13636-18-5, Fendiline (hydrochloride), MLS000069570, NCGC00094891-01, 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine hydrochloride, SMR000058827, DSSTox_CID_25860, DSSTox_RID_81180, DSSTox_GSID_45860, SR-01000003123, NCGC00018223-06, Prestwick_568, Sensit (TN), AC1NWASN, Fendiline(hydrochloride), Opera_ID_555, CAS-13636-18-5, MLS001076126, MLS002222223, SCHEMBL666530, SPECTRUM1501026, CHEMBL1405922, DTXSID2045860, CTK8F9736, MolPort-003-666-348, REGID_for_CID_5702162, HMS1568F22, HMS1921D11, Pharmakon1600-01501026, HY-B0984, KS-00001F9U, Tox21_111351, CCG-40224, NSC757826, AKOS030526089, Tox21_111351_1, API0008517, CS-4475, NSC-757826, NCGC00094891-02, NCGC00094891-03, NCGC00094891-04, FT-0630407, D07943, N-[3,3-Diphenylpropyl]-alpha-methylbenzylamine, A807067, C-20665, J-006837, SR-01000003123-3, SR-01000003123-4, N-(3,3-Diphenylpropyl)-?-methylbenzylamine hydrochloride, 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine hydrochloride

ID: 1484

InChIKey: NJYZGNRVYOLAFN-UHFFFAOYSA-N
SMILES: CCC(C1(CC(=NO1)C2=CC=C(C=C2)OC)C(=O)OC)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "EJ Niedzinski" "MF Springsteel" "AS Verkman" "MJ Haddadin" "LJ Galietta" "MJ Kurth" "K By" "M Eda"

CID is 10957318
synonyms found at PubChem are:
3-(4-Methoxyphenyl)-5-(1-hydroxypropyl)-2-isoxazoline-5-carboxylic acid methyl ester

ID: 1485

InChIKey: NKDFYOWSKOHCCO-UHFFFAOYSA-N
SMILES: CC12CCC3C(=CC(=O)C4C3(CC(C(C4)O)O)C)C1(CCC2C(C)(C(CCC(C)(C)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 271605
synonyms found at PubChem are:
Ecdysterone, Polypodine A, 20-HYDROXYECDYSONE, Crustecdysone, Hydroxyecdysone, 2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, beta-ECDYSTERONE, AC1L6QLT, CTK7J8705, MolPort-008-322-993, 2,3,14-Trihydroxy-10,13-dimethyl-17-(1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one, ALBB-030599, BBL010604, MFCD20529099, STK801665, AKOS005607788, MCULE-1655274985, I06-0013, 2 beta,3beta,14alpha,20 beta,22,25-Hexahydroxy-7-cholesten-6-one, 2 beta,3 beta,14alpha,20 beta,22,25-Hexahydroxy-7-cholesten-6-one, 2,3,14-trihydroxy-10,13-dimethyl-17-(2,3,6-trihydroxy-6-methylheptan-2-yl)-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one, 4,5,11-trihydroxy-2,15-dimethyl-14-(2,3,6-trihydroxy-6-methylheptan-2-yl)tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-9-en-8-one, 4,5,11-trihydroxy-2,15-dimethyl-14-(2,3,6-trihydroxy-6-methylheptan-2-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-en-8-one

ID: 1486

InChIKey: NKHBKSNSNVGJOE-UHFFFAOYSA-N
SMILES: CC(C1=NC2=CC=CC=C2C(=N1)N3CCCCC3)N4CCN(CC4)S(=O)(=O)C5=CC=C(C=C5)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"PA Sloane" "EJ Sorscher" "K Varga" "L Fan" "JP Clancy" "Y Li" "J Fulton" "J Collawn" "M Mazur" "SM Rowe" "B Woodworth" "J Fortenberry" "A Jurkevante" "LC Pyle"

CID is 23632303
synonyms found at PubChem are:
SCHEMBL1084332, VRT-640, KB-13518, 2-(1-{4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl}ethyl)-4-(1-piperidinyl)quinazoline, quinazoline, 2-[1-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]ethyl]-4-(1-piperidinyl)-

ID: 1487

InChIKey: NKXSNMCGZZWMMW-UHFFFAOYSA-N
SMILES: COC(=O)CCCOC1=C(C=C(C=C1)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1490
synonyms found at PubChem are:
Methyl 4-(2,4-dichlorophenoxy)butanoate, 18625-12-2, 2,4-DB methyl ester, Butanoic acid, 4-(2,4-dichlorophenoxy)-, methyl ester, 2,4-dichlorophenoxybutyric acid, methyl ester, Butyric acid, 4-(2,4-dichlorophenoxy)-, methyl ester, KBio2_002376, 2,4-DB-methylester, Spectrum_001863, 2,4-DB-methyl ester, SpecPlus_000474, AC1L1BLI, AC1Q3MGA, Spectrum2_001852, Spectrum3_000837, Spectrum4_000677, Spectrum5_001988, methyldichlorophenoxybutanoate, BSPBio_002393, KBioGR_001113, KBioSS_002380, SPECTRUM330045, DivK1c_006570, SPBio_001664, CHEMBL1448913, SCHEMBL12998521, CTK4D9194, KBio1_001514, KBio2_004944, KBio2_007512, KBio3_001893, DTXSID70171872, MolPort-001-757-615, NKXSNMCGZZWMMW-UHFFFAOYSA-N, KS-000024ZY, ZINC2512327, ZX-AT012265, CCG-39390, SBB102627, AKOS005072666, FA-0729, OR12132, RP14809, ACM18625122, Methyl 4-(2,4-dichlorophenoxy)butyrate, NCGC00094535-01, NCGC00094535-02, NCGC00094535-03, KB-256654, TR-030829, FT-0680988, 4-(2,4-Dichlorophenoxy)butyric acid methyl ester, J-522222, Butanoic acid, 4-(2,4-dichlorophenoxy)-, methylated, Butanoic acid,4-(2,4-dichlorophenoxy)-, methyl ester, Butanoic acid,4-(2,4-dichlorophenoxy)-,methyl ester, I01-10229, 2,4-DB-methyl ester, PESTANAL(R), analytical standard, 2,4-DB Methyl Ester (4-(2,4-Dichlorophenoxy)butanoic Acid Methyl Ester)

ID: 1488

InChIKey: NLBYRERHXBTBBR-UHFFFAOYSA-N
SMILES: CC(=O)OCC(CC(CCCCCCCCCCCC=C)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3624980
synonyms found at PubChem are:
Avocadene 1-acetate, 2,4-dihydroxyheptadec-16-enyl acetate, 2,4-dihydroxyheptadec-16-en-1-yl acetate, KBio2_007256, AC1MUVUS, Spectrum_001640, AVOCADENE ACETATE, KBioSS_002120, SPECTRUM240560, SCHEMBL898834, CHEMBL1443413, KBio2_002120, KBio2_004688, DTXSID00394411, MolPort-003-665-923, NLBYRERHXBTBBR-UHFFFAOYSA-N, LMFA05000640, 1-Acetoxy-16-heptadecene-2,4-diol, CCG-214721, MCULE-6841786527, SDCCGMLS-0066477.P001, NCGC00095546-01, 1-acetoxy-2,4-dihydroxy-n-heptadeca-16-en, 1-acetoxy-2,4-dihydroxy-n-heptadeca-16-ene, NCGC00095546-02!2,4-dihydroxyheptadec-16-enyl acetate, 24607-09-8

ID: 1489

InChIKey: NLJVXZFCYKWXLH-DXTIXLATSA-N
SMILES: CC(C)C[C@H]1C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](C(=O)[C@@H](NC(=O)[C@@H](N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN)C(C)C)CC3=CC=C(C=C3)O)CCC(=O)O)CC(=O)N)CC4=CC=CC=C4)CC5=CC=CC=C5)CC6=CC=CC=C6

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 452550
synonyms found at PubChem are:
tyrothricin, Dermotricine, Bactratycin, Coltirot, Martricin, Ginotricina, Hydrotricine, Pharothricetten, Rinotricina, Solutricine, Tirotricina, Tyrothricine, Tyrothricinum, Biothricin, Triciderm, Tyroderm, Tyrosur, Tyrozets, Tyrex, Dubos crude crystals, Intraderm tyrothricin, Caswell No. 900A, Tyri 10, Tirotricina [INN-Spanish], Tyrothricine [INN-French], Tyrothricinum [INN-Latin], 1404-88-2, EINECS 215-771-0, EPA Pesticide Chemical Code 006311, An antibacterial substance produced by the growth of Bacillus brevis Dubos (Fam. Bacteriaceae), Tyrothricin [INN:BAN], Soluthricin, Gramicidin A & Tyrocidine A, Tyrothricin [USP:INN:BAN], UNII-877376V2XW, AC1L9QDM, CHEMBL577736, 877376V2XW, AN-6594, LS-158334, 3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxo-ethyl)-9-(3-aminopropyl)-3,22,25-tribenzyl-15-[(4-hydroxyphenyl)methyl]-6-isobutyl-12-isopropyl-2,5,8,11,14,18,21,24,27-nonaoxo-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]pr, 3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxo-ethyl)-9-(3-aminopropyl)-3,22,25-tribenzyl-15-[(4-hydroxyphenyl)methyl]-6-isobutyl-12-isopropyl-2,5,8,11,14,18,21,24,27-nonaoxo-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid, 3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxoethyl)-9-(3-aminopropyl)-3,22,25-tribenzyl-15-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-2,5,8,11,14,18,21,24,27-nonaoxo-12-propan-2-yl-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid, Cyclic (-Val-Orn-Leu-D-Phe-Pro-Phe-D-Phe-Asn-Glu-Tyr-) Tyrocidine A & (HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH, ILe-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH) Gramicidin A

ID: 1490

InChIKey: NLLBWFFSGHKUSY-JPRRWYCFSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O.O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 16218542
synonyms found at PubChem are:
Rutoside trihydrate, 250249-75-3, Rutin hydrate, (+)-Rutin trihydrate, UNII-RF4N03853G, RF4N03853G, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one trihydrate, 207671-50-9, Rutoside trihydrate [EP], Rutin hydrate (JAN), KS-00000YGN, DTXSID50179735, MolPort-027-563-929, C27H30O16.3H2O, Rutin trihydrate, >=90% (HPLC), 6749AF, Rutin trihydrate, analytical standard, AKOS025310161, GS-3606, 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-l-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, trihydrate, ST24049136, D00190, Rutin trihydrate, primary pharmaceutical reference standard, Rutoside trihydrate, European Pharmacopoeia (EP) Reference Standard, Rutin trihydrate, United States Pharmacopeia (USP) Reference Standard, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one;trihydrate, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one trihydrate

ID: 1491

InChIKey: NLOALSPYZIIXEO-UHFFFAOYSA-N
SMILES: CC(CC1=CC(=CC=C1)C(F)(F)F)NCCOC(=O)C2=CC=CC=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 198015
synonyms found at PubChem are:
Benfluorex hydrochloride, 23642-66-2, Lipophoral, Mediaxal, Balans, Benfluorex (hydrochloride), EINECS 245-801-8, 2-((1-(3-(Trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride, NCGC00094832-01, 2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat, DSSTox_CID_25854, DSSTox_RID_81175, DSSTox_GSID_45854, W-110575, 2-((alpha-Methyl-m-(trifluoromethyl)phenethyl)amino)ethanol benzoate (ester), Benfluorex HCl, 2-((1-Methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl benzoate hydrochloride, 2-[[1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethyl benzoate hydrochloride, 2-{(1-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]ETHYL}AMINO)ETHYL BENZOATE HYDROCHLORIDE, Ethanol, 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-, benzoate (ester), HCl, Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, benzoate (ester), hydrochloride, SR-01000838831, 2-({1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethyl benzoate, chloride, 2-(1-(3-(trifluoromethyl)phenyl)propan-2-ylamino)ethyl benzoate hydrochloride, 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl benzoate hydrochloride, Mediator (TN), Prestwick_911, EINECS 245-020-2, AC1L54GH, CAS-23642-66-2, C19H21ClF3NO2, C19H20F3NO2.HCl, MLS002153789, SCHEMBL467300, SPECTRUM1500669, CHEMBL1412305, DTXSID8045854, CTK6A7113, MolPort-001-777-895, HMS1569I15, HMS1921A14, Pharmakon1600-01500669, 23602-78-0 (Parent), HY-B1058, ZX-AP006469, Tox21_111343, 1621AB, CCG-39155, NSC757396, PC8120, SBB057011, 2-(-Methyl-3-(trifluoromethyl)phenethylamino)ethyl benzoate hydrochloride, AKOS015994754, Tox21_111343_1, API0001607, CS-4580, MCULE-3872030067, NSC-757396, SS-4205, (1)-2-((1-Methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl benzoate hydrochloride, ACM23602780, NCGC00094832-02, NCGC00178369-05, 22471-86-9, KB-84009, LS-66957, SMR001233170, AX8115324, KB-227172, KB-282445, Benfluorex hydrochloride, analytical standard, FT-0602882, ST50993914, D07508, C-21487, SR-01000838831-3, SR-01000838831-4, 2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethylbenzoate hydrochloride, 2-{(1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethylbenzoate hydrochloride, Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, benzoate (ester),hydrochloride, AKOS015918371, A816795, I14-7667, benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester; hydron; chloride, hydron; 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl benzoate; chloride

ID: 1492

InChIKey: NLPRAJRHRHZCQQ-UHFFFAOYSA-N
SMILES: C1CC2C(CC1N2)C3=CN=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 1204
synonyms found at PubChem are:
(+/-)-Epibatidine, Epibatidine, [3H]EPIBATIDINE, [125I]EPIBATIDINE, CHEMBL6623, NLPRAJRHRHZCQQ-UHFFFAOYSA-N, 140111-52-0, 2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, 7-Azabicyclo[2.2.1]heptane, 2-(6-chloro-3-pyridinyl)-, 162599-17-9, (1R,2R,4S)-Epibatidine, SR-01000597620, Epibatidine-(+), Epibatidine-(-), ( )-Epibatidine, Epibatidine, (+/-), AC1L1AYB, AC1Q3PYA, 208/210 Epibatidine, D02CNL, D0R4RN, 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, BSPBio_001263, KBioGR_000603, KBioSS_000603, (R)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, exo-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, SCHEMBL316978, rac-(2R)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, 2-(6-chlor-3-pyridinyl)-7-azabicyclo[2.2.1]heptan, GTPL3976, GTPL3977, (2R)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane hydrochloride, 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane (epibatidine), 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane(+/-) epibatidine, CHEBI:91678, CTK8E8293, KBio2_000603, KBio2_003171, KBio2_005739, KBio3_001065, KBio3_001066, MolPort-003-983-567, Bio2_000462, Bio2_000942, HMS1362O05, HMS1792O05, HMS1990O05, HMS3403O05, 148152-66-3, BDBM50049757, AKOS023808322, CCG-208204, IDI1_002217, NCGC00024730-02, NCGC00024730-03, NCGC00024730-04, NCGC00024730-05, RT-012439, J-007356, SR-01000597620-1, SR-01000597620-3, 2-(6-Chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptane, BRD-A39268308-001-02-0, 2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, 3-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, ()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, (+)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, (-)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, 2-(6-Chloro-pyridin-3-yl)-7-azonia-bicyclo[2.2.1]heptane, (+/-)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane, (1R,2R,4S)-2-(6-Chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, (2R,4S)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, (2R,4S)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane, 2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane, (R)-2-(6-Chloro-pyridin-3-yl)-7-methyl-7-aza-bicyclo[2.2.1]heptane, 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane(Epibatidine)

ID: 1493

InChIKey: NLVFBUXFDBBNBW-PBSUHMDJSA-N
SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 36294
synonyms found at PubChem are:
tobramycin, 32986-56-4, Nebramycin 6, Nebramycin VI, Tobramicin, Tobramycetin, Nebcin, 3'-Deoxykanamycin B, Aktob, Tobi, NEBRAMYCIN, Nebramycin factor 6, Tobramycinum, Tobralex, Tobramicina, Tobramycine, 1-Epitobramycin, Deoxykanamycin B, Tobracin, Gotabiotic, Nebicin, Tobacin, Tobrased, Tobramycin Base, Tobi Podhaler, Tenebrimycin, Tobradistin, Tobramaxin, Tobramitsetin, Tenemycin, Tobrex, TOBRAMYCIN SULFATE, Obramycin, Tobradex, UNII-VZ8RRZ51VK, Tobramycine [INN-French], Tobramycinum [INN-Latin], Tobramicina [INN-Spanish], Brulamycin, Tobracin (TN), Tobrasone, Nebramycin factir 6, HSDB 3259, C18H37N5O9, Lilly 47663, EINECS 251-322-5, VZ8RRZ51VK, SPRC-AB01, NSC 180514, BRN 1357507, Distobram, NF 6, CHEBI:28864, tobramycin solution for inhalation, NLVFBUXFDBBNBW-PBSUHMDJSA-N, Tobrex (TN), D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-4))-2-deoxy-, 4-(2,6-Diamino-2,3,6-trideoxy-alpha-D-glycopyranosyl)-6-(3-amino-3-deoxy-alpha-D-glycopyranosyl)-2-deoxystreptamine, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine, Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-tyrideoxy-alpha-D-ribohexopyranosyl-(1-6))-2-deoxy-, D-, Sybryx, vantobra, Bethkis, Nebcin (Sulfate), Kitabis Pak, Gernebcin, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxy-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol, (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-6))-2-deoxy-L-streptamine, Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-6))-2-deoxy-, D-, TOY, Tobramycin for Inhalation, SR-05000001726, torbamycin, TOA-(1-6)TOB-(4-1)TOC, Tobramycin,(S), Tobramycin [USAN:BAN:INN:JAN], NCGC00016814-01, TOA-(1-6)2TB-(4-1)TOC, (1S,2S,3R,4S,6R)-4,6-diamino-3-[(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside, (2S,3R,4S,5S,6R)-4-amino-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol, Bethkis (TN), CAS-32986-56-4, Nebramycin-Faktor 6, Tobramycin [2M+H], Tobramycin [USAN:USP:INN:BAN:JAN], Tobi (TN), Spectrum_001072, AC1Q2AOW, Prestwick3_000544, Spectrum2_000078, Spectrum3_000588, Spectrum4_000752, Spectrum5_001038, DSSTox_CID_3680, ro-2H-pyran-3,5-diol, Tobramycin (JP17/USP), AC1L1VI0, SCHEMBL2838, CHEMBL1747, DSSTox_RID_77144, DSSTox_GSID_23680, BSPBio_000587, BSPBio_002036, KBioGR_001104, KBioSS_001552, MLS000069544, BIDD:GT0503, SPECTRUM1500579, SPBio_000295, BPBio1_000647, DTXSID8023680, KBio2_001552, KBio2_004120, KBio2_006688, KBio3_001536, AOB5629, BIT0802, MolPort-003-665-548, ZX-AFC000193, 49842-07-1 (Sulfate), HMS2090B16, HMS2092M17, HMS2096N09, HMS3713N09, Pharmakon1600-01500579, HY-B0441, ZINC8214692, Tox21_110626, BDBM50366778, CCG-39936, MFCD00077885, NSC757352, s2514, AKOS016339662, AN-9578, API0004434, CS-2547, DB00684, KS-1405, NSC-757352, NCGC00178852-01, NCGC00178852-02, CC-35084, CPD000058793, SAM001246911, SC-45657, SMR000058793, SBI-0051915.P003, AB2000616, LS-146940, LS-187329, AB00513858, A-8891, C00397, D00063, J10405, AB00052438-12, AB00052438_13, AB00052438_14, 986T564, C-22669, SR-01000721898, Tobramycin, Antibiotic for Culture Media Use Only, Q-201837, SR-01000721898-2, SR-05000001726-1, SR-05000001726-2, BRD-K05619559-001-12-7, UNII-NQJ13I4Z9U component NLVFBUXFDBBNBW-PBSUHMDJSA-N, (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside, (2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahyd, (2S,3R,4S,5S,6R)-4-amino-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxytetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol, (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol, 11098-01-4, 11111-45-8, 34337-51-4, 37321-13-4, 4-AMINO-2-[4,6-DIAMINO-3-(3-AMINO-6-AMINOMETHYL-5-HYDROXY-TETRAHYDRO-PYRAN-2-YLOXY)-2-HYDROXY-CYCLOHEXYLOXY]-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,5-DIOL, 54330-95-9, 70322-33-7, D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribo-hexopyranosyl-(1->4)]-2-deoxy-, D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[2,6-diamino-2,3,6-trideoxy-.alpha.-D-ribohexopyranosyl-(1->4)]-2-deoxy-, D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1->4))-2-deoxy-, O-[3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-->6)]-O-[2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-->4)]-2-deoxy-D-streptamine, O-[3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)]-O-[2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1->4)]-2-deoxy-D-streptamine, O-3-Amino-3-deoxy-?-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-?-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine, O-3-Amino-3-deoxy-a-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-a -D-ribo-hexopyranosyl-(1-4)]-2-deoxy-D-streptamine, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine

ID: 1494

InChIKey: NLZUEZXRPGMBCV-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 31404
synonyms found at PubChem are:
2,6-Di-tert-butyl-4-methylphenol, 128-37-0, Butylated hydroxytoluene, Butylhydroxytoluene, 2,6-Di-tert-butyl-p-cresol, 2,6-Di-t-butyl-4-methylphenol, Ionol, DBPC, Dibunol, Stavox, BHT, Ionol CP, Impruvol, Topanol, Dalpac, Deenax, Ionole, Vianol, Antioxidant KB, 3,5-Di-tert-butyl-4-hydroxytoluene, Antioxidant 4K, Sumilizer BHT, Topanol O, Topanol OC, Vanlube PC, Antioxidant DBPC, Sustane BHT, Tenamene 3, Vanlube PCX, Antioxidant 29, Antioxidant 30, Nonox TBC, Tenox BHT, Chemanox 11, Ionol 1, Agidol, Catalin CAO-3, Advastab 401, Ionol (antioxidant), BUKS, Parabar 441, Paranox 441, 2,6-Di-tert-butyl-4-cresol, Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-, Catalin antioxydant 1, Antrancine 8, Butylated hydroxytoluol, Vulkanox KB, Di-tert-butyl-p-cresol, Dibutylated hydroxytoluene, Kerabit, Tonarol, Ional, 2,6-ditert-butyl-4-methylphenol, 2,6-Bis(1,1-dimethylethyl)-4-methylphenol, AO 4K, CAO 1, CAO 3, Di-tert-butyl-p-methylphenol, Antioxidant MPJ, Antioxidant 4, Toxolan P, Alkofen BP, o-Di-tert-butyl-p-methylphenol, Swanox BHT, Tenamen 3, Antox QT, Antioxidant 264, 4-Methyl-2,6-tert-butylphenol, Agidol 1, Bht (food grade), 2,6-Di-tert-butyl-1-hydroxy-4-methylbenzene, 2,6-Di-tert-butyl-p-methylphenol, AO 29, NCI-C03598, 2,6-DI-T-BUTYL-P-CRESOL, 4-Methyl-2,6-di-tert-butylphenol, Butyl hydroxy toluene, Antioxidant T 501, Nocrac 200, 2,6-Di-terc.butyl-p-kresol, 4-Hydroxy-3,5-di-tert-butyltoluene, Caswell No. 291A, Dbpc (technical grade), P 21, Annulex BHT, AOX 4K, Bht(food grade), 4-Methyl-2,6-di-terc. butylfenol, AOX 4, 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene, Di-tert-butylcresol, CCRIS 103, Butylohydroksytoluenu [Polish], UNII-1P9D0Z171K, Butylated hydroxytoluene (bht), FEMA No. 2184, Di-tert-butyl-p-cresol (VAN), Dbpc(technical grade), E321, HSDB 1147, p-Cresol, 2,6-di-tert-butyl-, BHT 264, 2,6-ditert-butyl-4-methyl-phenol, NSC 6347, EINECS 204-881-4, 2,6-Di-tert-butyl-4-hydroxytoluene, CHEMBL146, 2,6-Di-terc.butyl-p-kresol [Czech], EPA Pesticide Chemical Code 022105, 2,6-Di-tert-butyl-4-methylhydroxybenzene, AI3-19683, 4-Methyl-2,6-di-terc. butylfenol [Czech], CHEBI:34247, C15H24O, NLZUEZXRPGMBCV-UHFFFAOYSA-N, 1P9D0Z171K, 4-Methyl-2,6-di-t-butyl-phenol, 2,6-di-tert-butyl-4-methyl phenol, 2,6-Di-tert-butyl-4-methyl-phenol, 2,6-di-tert.-butyl-4-methylphenol, 2,6-bis(tert-butyl)-4-methylphenol, MFCD00011644, NCGC00091761-03, DSSTox_CID_216, DSSTox_RID_75440, DSSTox_GSID_20216, CAS-128-37-0, Butylohydroksytoluenu, Ionol CP-antioxidant, Ionol" CP-antioxidant, Dibutylcresol, Popol, 4-Methyl-2,6-ditertbutylphenol, Antracine 8, Embanox BHT, Hydagen DEO, Lowinox BHT, Nipanox BHT, BHT Swanox, BHT, food grade, Butylhydroxytoluenum, Ionol BHT, Ralox BHT, 2, food grade, Avox BHT, Butylated hydroxytoluene [BAN:NF], Dibutyl-para-cresol, Topanol OC and 0, Butylated hydroxytoluene [USAN:BAN], Additin RC 7110, PubChem20842, Spectrum_001790, ACMC-1BUTL, BHT FCC/NF, SpecPlus_000768, Methyldi-tert-butylphenol, AC1L1LJQ, AC1Q2GUH, Spectrum3_001849, Spectrum5_001612, Hydagen DEO (Salt/Mix), D0W1SL, EC 204-881-4, 2,6-di-Butyl-para-cresol, 2.6-di-t-butyl-p-cresol, SCHEMBL3950, 2,6-ditert-butyl-p-cresol, p-Cresol,6-di-tert-butyl-, BUTYLATEDHYDROXYTOLUENE, Di-tert-Butylparamethylphenol, BSPBio_003238, KBioSS_002281, 2,6-di-tert.butyl-p-cresol, Di-tert-Butyl-4-methylphenol, KSC496A5L, MLS000069425, BIDD:ER0031, Butylated hydroxytoluene (NF), DivK1c_006864, SPECTRUM1600716, 2,6-bis-tert-butyl-p-cresol, 2,6-di-tert-butyl-paracresol, BHT (butylated hydroxytoluene), 2,6-Di(tert-butyl)-p-cresol, 2,6-di-tert. butyl-p-cresol, 2,6-di-tert.-butyl-p-cresol, 2,6-di-tert-butyl-para-cresol, Jsp001764, 2,6-di-tert-Butyl-methylphenol, 2,6-ditertbutyl-4-methylphenol, DTXSID2020216, 2,6-di-t butyl-4-methylphenol, 2.6-di-t-butyl-4-methylphenol, CTK3J6055, FEMA 2184, KBio1_001808, KBio2_002280, KBio2_004848, KBio2_007416, KBio3_002738, KS-00000IQP, 2,6-di-tert-butyl-4methylphenol, 2,6-di-tert-butyl4-methylphenol, 2,6-di-tertbutyl-4-methylphenol, 2,6-ditert.butyl-4-methylphenol, 2.6-di-tert-butyl-4-methylenol, Butylated hydroxyl toluene (BHT), NSC6347, 2,6-Di(tert-butyl)hydroxytoluene, MolPort-000-872-015, 2,6-di(t-butyl)-4-methylphenol, 2,6-di-t- butyl-4-methylphenol, 2,6-di-t-butyl 4-methyl phenol, 2,6-di-t-butyl-4-methyl phenol, 2,6-di-t-butyl-4-methyl-phenol, 3,5-di-t-butyl-4-hydroxytoluene, AO-29, HMS2091E21, HMS2231M22, HMS3369G17, Pharmakon1600-01600716, 2,1-dimethylethyl)-4-methylphenol, 2,6-di-tert-butyl 4-methylphenol, 2,6-di-tert-butyl-4 methylphenol, 2,6-di-tert-butyl4-methyl phenol, 2,6-di-tert.butyl-4-methylphenol, 2,6-ditert.-butyl-4-methylphenol, 2.6-di-tert-butyl-4-methylphenol, 4-methyl-2,6-di-tert.butylphenol, 2,6-di-ter-butyl-4-methyl-phenol, 2,6-Di-tert.-Butyl4-methylphenol, 2,6-ditertiarybutyl-4-methylphenol, 2.6-di- t-butyl- 4-methylphenol, NSC-6347, STR04334, ZINC1481993, 2,6 -di-tert-butyl-4-methylphenol, 2,6-di(tert-butyl)-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, 8CI, Tox21_113537, Tox21_201093, Tox21_303408, 2,6-di-tert-butyl-p-cresol (BHT), 2,6-Di-tert-butyl-para-methylphenol, ANW-19063, BDBM50079507, LS-716, NSC759563, SBB040854, STL277184, 2,6-di-tert. butyl-4-methyl phenol, 2,6-Di-(tert-butyl)-4-methylphenol, 2,6-di-tert-butyl-p-cresol (DBPC), AKOS000269037, Tox21_113537_1, 4-Hydroxy-3,5- Di-tert-Butyltoluene, CCG-207937, CM14391, CS-W020053, MCULE-4627478482, NSC-759563, RP27273, RTR-003997, TRA0000041, Phenol, 2,6-di-tert-butyl-4-methyl-, NCGC00091761-01, NCGC00091761-02, NCGC00091761-04, NCGC00091761-05, NCGC00091761-06, NCGC00091761-07, NCGC00257275-01, NCGC00258645-01, AC-10553, AJ-26305, AN-43610, CJ-05085, KB-67744, L133, SC-19397, SMR000059076, 2,6-Di-tert-butyl-4-methylphenol (BHT), 2,6-Di-tert-butyl-4-methylphenol, 99%, BUTYLATED HYDROXYTOLUENE CRYSTALLINE, SBI-0052890.P002, KB-166086, ST2409168, TL8006085, TR-003997, 2,6-Di-tert-butyl-4-methylphenol, >=99%, Butylated hydroxytoluene, >=99%, FCC, FG, D0228, FT-0610731, Phenol,6-bis(1,1-dimethylethyl)-4-methyl-, ST50214443, 2,6-bis-(1,1-dimethylethyl)-4-methylphenol, PK04_181024, 2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene, C14693, D02413, M-6087, MLS-0146297.0001, AB00053233_09, Phenol, 3,5-bis(1,1-dimethylethyl)-4-methyl-, 2,6-Bis(1,1-dimethylethyl)-4-methylphenol, 9CI, 2,6-Di-tert-butyl-4-methylphenol, 99% 250g, 2,6-Di-tert-butyl-4-methylphenol, puriss., 99%, AC-907/25014329, SR-01000735918, I01-6986, SR-01000735918-2, W-108376, 9FC4DFC8-480D-487C-A74A-2EC9EECE92C4, BENZENE,1,3-DITERT.BUTYL,2-HYDROXY,5-METHYL, BRD-K53153417-001-01-3, BRD-K53153417-001-06-2, 2,6-D[(CH3)3C]2C6H2(CH3)OHi-tert-butyl-p-cresol, F0001-0395, Z955123624, 2,6-Di-tert-butyl-4-methylphenol, purum, >=99.0% (GC), WLN: 1X1 & 1 & R BQ E1 CX1 & 1 & 1, 2,6-Di-tert-butyl-4-methylphenol, >=99.0% (GC), powder, 2,6-Di-tert-butyl-4-methylphenol, SAJ first grade, >=99.0%, 2,6-Di-tert-butyl-4-methylphenol, tested according to Ph.Eur., 3,5-Di-tert-4-butylhydroxytoluene (BHT), analytical standard, Butylhydroxytoluene, European Pharmacopoeia (EP) Reference Standard, 2,6-Di-tert-butyl-4-methylphenol, certified reference material, TraceCERT(R), Butylated Hydroxytoluene, Pharmaceutical Secondary Standard; Certified Reference Material, Butylated hydroxytoluene, United States Pharmacopeia (USP) Reference Standard, 102962-45-8, 259752-53-9, 290348-23-1, 42615-30-5, 50356-19-9, 50641-99-1, 52683-46-2, 53571-70-3, 58500-82-6, 83047-16-9, 97123-41-6, InChI=1/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H

ID: 1495

InChIKey: NMHJRGCKGFRFAQ-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)I)CN=C(N)N.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 2736646
synonyms found at PubChem are:
Iobenguane sulfate, MIBG, m-Iodobenzylguanidine sulfate, m-Iodobenzylguanidine, Hemisulfate, 3-Iodobenzylguanidine, Hemisulfate, 103346-16-3, 3-Iodo-Benzyl-guanidinium-sulfate, m-Iodobenzylguanidine hemisulfate salt, 2-[(3-iodophenyl)methyl]guanidine; sulfuric acid, SR-01000075167, Prestwick_801, 80663-96-3, AC1MC08D, MLS002153841, SCHEMBL9798682, CHEMBL1255738, MolPort-000-156-449, NMHJRGCKGFRFAQ-UHFFFAOYSA-N, 1-(3-iodobenzyl)guanidine sulfate, HMS1569B21, HMS2096B21, HMS2232O12, HMS3373L01, HMS3713B21, ZX-AT018249, N-(3-Iodobenzyl)guanidinium sulphate, OR6467, AKOS015910879, API0006016, CCG-220490, NCGC00180966-01, SMR001233204, RT-014115, 1-[(3-iodophenyl)methyl]guanidine; sulfuric acid, SR-01000075167-5, I14-38836, AC1MC61O, [amino(azaniumyl)methylidene]-[(3-iodophenyl)methyl]azanium sulfate

ID: 1496

InChIKey: NMHKTASGTFXJPL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCC[N+]1=CSC=C1)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 107681
synonyms found at PubChem are:
CV-3988, 3-Motp, CV 3988, 85703-73-7, CV3988, CHEMBL295212, 2-Methoxy-3-(octadecylcarbamoyloxy)propyl-2-(3-thiazolinium) ethyl phosphate, 3-(N-n-Octadecylcarbamoyloxy)-2-methoxypropyl-2-thiazolinium ethyl phosphate, 2-methoxy-3-[(octadecylcarbamoyl)oxy]propyl 2-(1,3-thiazol-3-ium-3-yl)ethyl phosphate, CV-3988 hydrate, 92203-21-9, Thiazolium, 3-(4-hydroxy-7-methoxy-10-oxo-3,5,9-trioxa-11-aza-4-phosphanonacos-1-yl)-, hydroxide, inner salt, P-oxide, (+-)-, [2-methoxy-3-(octadecylcarbamoyloxy)propyl] 2-(1,3-thiazol-3-ium-3-yl)ethyl phosphate, Thiazolium, 3-(4-hydroxy-7-methoxy-10-oxo-3,5,9-trioxa-11-aza-4-phosphanonacos-1-yl)-, inner salt, C28H53N2O7PS, D0N2WK, AC1L32JM, AC1Q63EO, GTPL6079, SCHEMBL8701203, CTK8D5538, DTXSID40276040, NMHKTASGTFXJPL-UHFFFAOYSA-N, BDBM50006048, MFCD19053159, CCG-205137, LP01060, NCGC00015263-02, NCGC00015263-03, NCGC00015263-04, NCGC00094342-01, NCGC00162331-01, LS-177889, EU-0101060, C 7238, (R,S)-2-methoxy-3-(octadecyl-carbamoyloxy) propyl- 2-(3-thia, (+/-)-(3-(N-Octadecylcarbamoyloxy)-2-methoxy)propyl-2-thiazolioethyl phosphate, (+/-)-[3-(N-Octadecylcarbamoyloxy)-2-methoxy]propyl 2-thiazolioethyl phosphate hydrate, 2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(thiazol-3-ium-3-yl)ethyl phosphate, 3-{2-[(2-Methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphonooxy-methoxy]-ethyl}-thiazol-3-ium, 3-{2-[Hydroxy-(2-methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphoryloxy]-ethyl}-thiazol-3-ium, 3-{2-[Hydroxy-(2-methoxy-3-octadecylcarbamoyloxy-propoxy)-phosphoryloxy]-ethyl}-thiazol-3-ium(CV-3988), Octadecyl-carbamic acid 3-[hydroxy-(2-thiazol-3-yl-ethoxy)-phosphorylo xy]-2-methoxy-propyl ester(CV-3988)

ID: 1497

InChIKey: NMLUOJBSAYAYEM-AZQGJTAVSA-N
SMILES: CC[C@H]1CN2CCC3=C([C@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)NC4=CC=CC=C34

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3037884
synonyms found at PubChem are:
Hirsutine, 7729-23-9, UNII-W596OF93C7, CHEMBL327134, W596OF93C7, (E)-16,17-Didehydro-17-methoxy-17,18-seco-3-beta-yohimban-16-carboxylic acid methyl ester, 17,18-Seco-3-beta-yohimban-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (E)-, AC1MI3P9, BDBM50396011, ZINC26846321, LS-144744, C16972, 729H239, Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3-beta,16E)-, Corynan-16-carboxylic acid, 16,17-didehydro-17-methoxy-, methyl ester, (3-beta,16E)- (9CI), methyl (E)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate

ID: 1498

InChIKey: NMUSYJAQQFHJEW-OEXCPVAWSA-N
SMILES: C1=NC(=NC(=O)N1C2[C@H]([C@H]([C@H](O2)CO)O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 6420049
synonyms found at PubChem are:
Azacytidine-5, Prestwick_972, AC1O4WIL, Prestwick0_000866, Prestwick1_000866, Prestwick2_000866, SPBio_002832, SCHEMBL16187746, HMS1570N13, 4-amino-1-[(3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

ID: 1499

InChIKey: NNKVPIKMPCQWCG-UHFFFAOYSA-N
SMILES: COP(=O)(N)SC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 4096
synonyms found at PubChem are:
methamidophos, Metamidophos, Tamaron, Pillaron, Tahmabon, Amidor, Filitox, Hamidop, Patrole, Tamanox, Acephate-met, 10265-92-6, Sniper, Ortho Monitor, MONITOR, O,S-Dimethyl phosphoramidothioate, Metamidofos estrella, Monitor (insecticide), Chevron 9006, Chevron ortho 9006, Bayer 5546, Phosphoramidothioic acid, O,S-dimethyl ester, Ortho 9006, Caswell No. 378A, Methamidophos [ANSI:BSI:ISO], CKB 1220, SRA 5172, ENT 27,396, NSC 190987, RE 9006, o,S-Dimethyl amidothiophosphate, CHEBI:38721, HSDB 1593, Methyl phosphoramidothioate ((MeO)(MeS)P(O)(NH2)), O,S-Dimethyl phosphoramidothiolate, EINECS 233-606-0, Methyl phosphoramidothioate, EPA Pesticide Chemical Code 101201, BRN 1098870, Thiophosphorsaeure-O,S-dimethylesteramid, AI3-27396, MTD, BAYER 71628, O,S-dimethyl phosphoroamidothioate, NNKVPIKMPCQWCG-UHFFFAOYSA-N, Thiophosphorsaeure-O,S-dimethylesteramid [German], [amino(methylsulfanyl)phosphoryl]oxymethane, DSSTox_CID_4177, DSSTox_RID_77318, DSSTox_GSID_24177, Q-201361, Methamidophos, analytical standard, 115182-35-9, (-)-Methamidophos, CAS-10265-92-6, L-(-)-Methamidophos, cekumidofos, giant, jiaanlin, methaphos, Nitofol, CCRIS 9422, O,S-dimethylphosphoroamidothioate, Methamidophos E.C., Methamidophos solution, (+/-)-Methamidophos, Spectrum_001799, SpecPlus_000390, AC1L1HEJ, Spectrum2_001863, Spectrum3_000815, Spectrum4_000655, Spectrum5_001940, SCHEMBL23291, BSPBio_002309, KBioGR_001029, KBioSS_002292, SPECTRUM330023, DivK1c_006486, SPBio_001706, CHEMBL504888, DTXSID6024177, CTK4A1369, KBio1_001430, KBio2_002290, KBio2_004858, KBio2_007426, KBio3_001809, O,S-Dimethyl amidothiophosphate #, Tox21_202250, Tox21_300740, BAY 71628, BDBM50027341, CCG-39401, FCH831966, AKOS006228092, [methoxy(methylsulfanyl)phosphoryl]amine, NCGC00094520-01, NCGC00094520-02, NCGC00094520-03, NCGC00094520-04, NCGC00094520-05, NCGC00094520-06, NCGC00094520-07, NCGC00094520-08, NCGC00254646-01, NCGC00259799-01, 65960-97-6, CC-30255, thiophosphoramidic acid O,S-dimethyl ester, LS-107406, Methamidophos 10 microg/mL in Acetonitrile, Phosphoramidothioicacid, O,S-dimethyl ester, FT-0630379, Methamidophos 100 microg/mL in Ethylacetate, O,S-Dimethyl ester of amidothiophosphoric acid, C18667, 74438-EP2275422A1, 74438-EP2292608A1, 74438-EP2305662A1, 74438-EP2308857A1, Methamidophos, PESTANAL(R), analytical standard, 265M926, C-02040, Phosphoramidothioic acid, O,S-dimethyl ester, (S)-, I14-17772, UNII-8Z083FM94W component NNKVPIKMPCQWCG-LURJTMIESA-N, Pesticide1_Methamidophos_C2H8NO2PS_O,S-Dimethyl phosphoramidothioate, Methamidophos solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard

ID: 1500

InChIKey: NNYBQONXHNTVIJ-UHFFFAOYSA-N
SMILES: CCC1=CC=CC2=C1NC3=C2CCOC3(CC)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"B Kus" "J Goepp" "D Rotin" "JW Hanrahan" "SD Macknight" "R Robert" "DY Thomas" "E Matthes" "GW Carlile" "J Liao"

CID is 3308
synonyms found at PubChem are:
etodolac, 41340-25-4, Etodolic acid, Lodine, Ultradol, Lodine XL, Etodolaco, Etodolacum, Ramodar, AY 24236, Etodolacum [INN-Latin], Etodolaco [INN-Spanish], AY-24236, AY-24,236, Edolan, Hypen, CCRIS 3923, 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid, CHEMBL622, NSC 282126, 1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid, 1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, MLS000028474, CHEBI:4909, RAK-591, NNYBQONXHNTVIJ-UHFFFAOYSA-N, 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid, (1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid, 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid, Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, NSC282126, SMR000058443, DSSTox_CID_615, (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid, (+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, DSSTox_RID_75691, DSSTox_GSID_20615, Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-(+-)-, SR-01000000100, etodine, Etodolac [USAN:BAN:INN], Etodolac [USAN:INN:BAN], Etodolsaure, Osteluc, Tedolan, Zedolac, etodolac o, rac-Etodolac, Etodlic Acid, [1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid, Etodolac(Lodine), Lodine SR, KS-1056, Etodolac [USAN:USP:INN:BAN], NCGC00016849-01, Etodolac,(S), Prestwick_209, Etodolacetodolic acid, CAS-41340-25-4, Lodine (TN), Spectrum_001244, Opera_ID_1774, Prestwick0_000231, Prestwick1_000231, Prestwick2_000231, Prestwick3_000231, Spectrum2_001387, Spectrum3_001429, Spectrum4_000410, Spectrum5_001347, D0N1WU, AC1L1FN2, SCHEMBL3903, Lopac0_000479, BSPBio_000301, BSPBio_003138, KBioGR_000680, KBioSS_001724, MLS001077315, MLS006011566, DivK1c_000147, SPECTRUM1501005, Etodolac (JP17/USP/INN), SPBio_001374, SPBio_002222, BPBio1_000333, GTPL7185, DTXSID9020615, CTK4I4719, HMS500H09, KBio1_000147, KBio2_001724, KBio2_004292, KBio2_006860, KBio3_002358, MolPort-001-759-084, NINDS_000147, HMS1568P03, HMS1921B09, HMS2092O20, HMS2095P03, HMS2231D04, HMS3259P10, HMS3261O20, HMS3374G09, HMS3712P03, Pharmakon1600-01501005, BCP28411, Tox21_110644, Tox21_202218, Tox21_500479, ANW-42024, BDBM50016799, CCG-39005, CE0096, MFCD00133313, NSC757821, AKOS015838610, Tox21_110644_1, AC-4231, CS-0832, DB00749, LP00479, LS-7393, NC00718, NSC-282126, NSC-757821, RTR-036749, IDI1_000147, KS-0000000W, NCGC00015399-03, NCGC00015399-04, NCGC00015399-05, NCGC00015399-06, NCGC00015399-07, NCGC00015399-08, NCGC00015399-09, NCGC00015399-11, NCGC00015399-12, NCGC00015399-13, NCGC00015399-15, NCGC00015399-16, NCGC00089769-02, NCGC00089769-03, NCGC00089769-04, NCGC00089769-05, NCGC00089769-06, NCGC00089769-07, NCGC00259767-01, NCGC00261164-01, AN-12214, BC651843, CPD000058443, HY-76251, SAM002589968, SBI-0050463.P003, 110781-63-0 (mono-hydrochloride salt), AB0012214, TR-036749, AB00052194, E0858, EU-0100479, FT-0607046, C06991, D00315, E 0516, K-8734, Pyrano[3, 1,8-diethyl-1,3,4,9-tetrahydro-, AB00052194_17, 340E254, Q-201099, SR-01000000100-2, SR-01000000100-4, SR-01000000100-7, BRD-A74667430-001-05-3, BRD-A74667430-001-15-2, 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, Etodolac, European Pharmacopoeia (EP) Reference Standard, F2173-0681, Z1820178466, Etodolac, United States Pharmacopeia (USP) Reference Standard, 1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid, 1,8-Diethyl-1,3,4,9-tetrahydropyranol[3,4-b]indole-1-acetic acid, (RS)-2-(1,8-Diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid, Pyrano(3,4,b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, Etodolac for peak identification, European Pharmacopoeia (EP) Reference Standard