CandActCFTR Seed Compounds

The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.


ID: 2501

chemical graph of compound 2501



InChIKey: WRFQRUBJBPLPAM-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5482101
synonyms found at PubChem are:
Geraldol, 21511-25-1, 3'-Methoxy-3,7,4'-trihydroxyflavone, 3,7,4'-Trihydroxy-3'-methoxyflavone, 3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, geraldo l, Geraldol (13), PubChem9854, AC1NULME, SCHEMBL620712, SPECTRUM1505149, BIDF1020, CHEMBL509256, DTXSID30175851, WRFQRUBJBPLPAM-UHFFFAOYSA-N, ZX-AFC002770, BDBM153269, ZINC5732763, EINECS 244-414-1, LMPK12111568, MFCD00017311, CCG-208646, MCULE-9454526527, ACM21511251, NCGC00096044-01, CC-28961, FT-0630473, ST50331616, A815437, C-18745, 3,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone, 3,7-dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one, 3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one, 2-(3-methoxy-4-oxidanyl-phenyl)-3,7-bis(oxidanyl)chromen-4-one, 3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-benzopyran-4-one

ID: 2502

chemical graph of compound 2502



InChIKey: WRINBBKPZKSBMR-UHFFFAOYSA-N
SMILES: COc1ccc(cc1)C2c3c([nH]nc3OC(=C2C#N)N)c4ccccc4

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"Y Seo" "W Namkung" "J Park" "AS Verkman"


CID is 3125753
synonyms found at PubChem are:
6-amino-4-(4-methoxyphenyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, AC1MISAM, Oprea1_228801, Oprea1_341622, Oprea1_817016, MolPort-000-816-520, MolPort-000-919-276, WRINBBKPZKSBMR-UHFFFAOYSA-N, RSC000082, STK744133, AKOS000675459, AKOS003233956, AKOS021990586, CCG-106730, MCULE-1734929398, BAS 01108025, ST071131, J3.663.100G, AK-777/11282102, SR-01000434707, SR-01000434707-1, A1883/0079219, 3-Phenyl-4-(4-methoxyphenyl)-6-amino-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(4-methoxyphenyl)-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(4-methoxyphenyl)-3-phenyl-4H-pyrano[3,2-d]pyrazole-5-carbonitrile, 330158-65-1

ID: 2503

chemical graph of compound 2503



InChIKey: WROKSYFOSDWFHL-UQVLWQGYSA-N
SMILES: CC(=O)O[C@H]1C[C@H](C(C2[C@]1(C3CC[C@]4([C@@H](OC(=O)C5C4([C@@]3(C(=O)C2)C)O5)C(=O)O)C)C)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708640
synonyms found at PubChem are:
DEACETOXY(7)-7-OXOKHIVORINIC ACID, KBio2_006165, Spectrum_000549, SpecPlus_000291, Spectrum2_000336, Spectrum3_000085, Spectrum4_001369, Spectrum5_000018, BSPBio_001610, KBioGR_001638, KBioSS_001029, SPECTRUM100447, DivK1c_006387, SPBio_000371, KBio1_001331, KBio2_001029, KBio2_003597, KBio3_000690, CCG-38611, SDCCGMLS-0066290.P001, NCGC00179153-01, SR-05000002735, SR-05000002735-1, BRD-A34842997-001-03-1

ID: 2504

chemical graph of compound 2504



InChIKey: WRQBEFIJZLEUBS-NDENLUEZSA-N
SMILES: CC1=CC(=C(N1C2=CC=C(C=C2)OC)C)/C=C\3/C(=O)NC(=O)N(C3=O)CC4=CC=CO4

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"A Taddei" "T Ma" "VS Gopinath" "H Yang" "N Pedemonte" "RK Guy" "GL Lukacs" "AA Shelat" "LJ Galietta" "AS Verkman" "K Du" "C Folli"


CID is 1349528
synonyms found at PubChem are:
AC1LQF9X, SCHEMBL3113918, MolPort-002-194-707, HMS1586E02, ZINC15800021, SR-01000232745, SR-01000232745-1, (5Z)-1-(furan-2-ylmethyl)-5-[[1-(4-methoxyphenyl)-2,5-dimethylpyrrol-3-yl]methylidene]-1,3-diazinane-2,4,6-trione

ID: 2505

chemical graph of compound 2505



InChIKey: WSACHQJPCNOREV-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C3=C(O2)C=CC(=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 74708
synonyms found at PubChem are:
2-Hydroxyxanthone, 2-hydroxyxanthen-9-one, 1915-98-6, Xanthen-9-one, 2-hydroxy-, 2-Hydroxy-9H-xanthen-9-one, 9H-XANTHEN-9-ONE, 2-HYDROXY-, 2-Hydroxy-xanthen-9-one, CHEMBL185960, WSACHQJPCNOREV-UHFFFAOYSA-N, KBio2_003149, Spectrum_000121, AC1L2MHJ, Spectrum2_001722, Spectrum3_001190, Spectrum4_001616, Spectrum5_000371, 2-hydroxy-9H-9-xanthenone, BSPBio_002839, KBioGR_001991, KBioSS_000581, SPBio_001764, 2-hydroxy-9H-xanthene-9-one, AC1Q6E29, SCHEMBL1675981, CTK4E0732, KBio2_000581, KBio2_005717, KBio3_002339, 2-Hydroxy-9H-xanthen-9-one #, DTXSID60172676, CHEBI:108579, ZINC3979037, ZX-AT027956, 2-Hydroxy-9H-xanthen-9-one, 9CI, BDBM50155409, CCG-38792, AKOS022650645, ACM1915986, SDCCGMLS-0066534.P001, NCGC00178442-01, AM20030247, BRD-K12336887-001-02-3

ID: 2506

chemical graph of compound 2506



InChIKey: WSKWDXWDFFVUKX-UHFFFAOYSA-N
SMILES: COC1=CC(=CC(=C1OC)O)C2=COC3=CC(=C(C(=C3C2=O)O)OC)OCC4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6063287
synonyms found at PubChem are:
IRIGENIN, 7-BENZYL ETHER, KBio2_003665, Spectrum_000617, SpecPlus_000061, Spectrum2_000200, Spectrum3_000190, Spectrum4_001509, Spectrum5_000277, BSPBio_001719, KBioGR_002177, KBioSS_001097, SPECTRUM200763, DivK1c_006157, SPBio_000159, AC1O16A4, CHEMBL1486474, KBio1_001101, KBio2_001097, KBio2_006233, KBio3_001219, CHEBI:107632, CCG-38406, SDCCGMLS-0066434.P001, NCGC00095489-01, NCGC00095489-02, NCGC00179062-01, SR-05000002678, SR-05000002678-1, BRD-K53634892-001-02-4, BRD-K53634892-001-03-2, 5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-7-phenylmethoxychromen-4-one

ID: 2507

chemical graph of compound 2507



InChIKey: WSSJONWNBBTCMG-UHFFFAOYSA-N
SMILES: CC1CC(CC(C1)(C)C)OC(=O)C2=CC=CC=C2O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8362
synonyms found at PubChem are:
Homosalate, 118-56-9, Homomenthyl salicylate, 3,3,5-TRIMETHYLCYCLOHEXYL SALICYLATE, Coppertone, Heliopan, Heliophan, Filtersol ''A'', m-Homomenthyl salicylate, Homosalatum, Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester, Caswell No. 482B, Filtrosol A, Homosalatum [INN-Latin], Homosalato [INN-Spanish], 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate, NSC 164918, CCRIS 4885, component of Coppertone, Salicylic acid, m-homomenthyl ester, Metahomomenthyl salicylate, (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate, EINECS 204-260-8, EPA Pesticide Chemical Code 076603, Salicylic Acid 3,3,5-Trimethylcyclohexyl Ester, WSSJONWNBBTCMG-UHFFFAOYSA-N, 2-Hydroxybenzoic acid 3,3,5-trimethylcyclohexyl ester, 52253-93-7, NCGC00091888-01, DSSTox_CID_6241, Salicylic acid, 3,3,5-trimethylcyclohexyl ester, DSSTox_RID_78073, DSSTox_GSID_26241, 8045-71-4, Homosalato, SR-05000001884, Homosalate [USAN:INN], kemester, Homosalat, Homosalate [USAN:USP:INN], Kemester HMS, CAS-118-56-9, Homosalate (USP/INN), AC1Q2QMQ, Prestwick1_001090, Prestwick2_001090, Prestwick3_001090, EC 204-260-8, AC1L1QU5, SCHEMBL16207, Trimethylcyclohenyl salicylate, BSPBio_001140, SPECTRUM1505020, SPBio_003030, BPBio1_001254, CHEMBL1377575, DTXSID1026241, CHEBI:91642, CTK5E7804, KS-00000NCC, MolPort-001-793-236, 3,5-Trimethylcyclohexyl salicylate, HMS1571I22, HMS2093G22, HMS2098I22, HMS3715I22, Pharmakon1600-01505020, component of Coppertone (Salt/Mix), HY-B0928, 3,3,5-Trimethylcyclohexylsalicylate, Tox21_111174, Tox21_202109, Tox21_303082, 6350AF, ACM118569, LS-600, NSC164918, NSC758908, AKOS015904082, Tox21_111174_1, CCG-213330, MCULE-8750002732, NSC-164918, NSC-758908, RL00712, NCGC00091888-02, NCGC00091888-03, NCGC00091888-04, NCGC00091888-05, NCGC00091888-06, NCGC00091888-09, NCGC00257063-01, NCGC00259658-01, AN-43272, AS-10409, CC-12864, SBI-0206787.P001, AB00514041, FT-0614020, Salicylic acid,3,5-trimethylcyclohexyl ester, Benzoic acid, 3,3,5-trimethylcyclohexyl ester, D04450, AB00514041_02, C-35420, J-519754, SR-05000001884-1, SR-05000001884-2, benzoicacid,2-hydroxy-,3,3,5-trimethylcyclohexylester, BRD-A34751532-001-03-6, BRD-A34751532-001-04-4, I14-17920, 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester, Salicylic acid, 3,3,5-trimethylcyclohexyl ester (8CI), 3,3,5-Trimethylcyclohexyl salicylate (cis- and trans- mixture), Homosalate, United States Pharmacopeia (USP) Reference Standard, Benzoic acid,2-hydroxy-, 3,3,5-trimethylcyclohexyl ester; Homosalate, Homosalate, Pharmaceutical Secondary Standard; Certified Reference Material, 194304-23-9, 50610-40-7

ID: 2508

chemical graph of compound 2508



InChIKey: WSXKZIDINJKWPM-IBGZLQDMSA-N
SMILES: CC(CCC=C(C)C)NC.CC(CCC=C(C)C)NC.[C@@H]([C@@H]([C@H](C(=O)O)O)O)([C@@H](C(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 15605556
synonyms found at PubChem are:
Isometheptene mucate (USP), Isometheptene mucate [USP], NCGC00017158-02, Isometheptene Mucate, USP, DSSTox_CID_28788, DSSTox_RID_83057, UNII-8O120FDS6P, DSSTox_GSID_48862, SCHEMBL94782, 8O120FDS6P, CHEMBL2355839, DTXSID8048862, Tox21_113355, CAS-7492-31-1, D07097

ID: 2509

chemical graph of compound 2509



InChIKey: WTDHULULXKLSOZ-UHFFFAOYSA-N
SMILES: NO.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 443297
synonyms found at PubChem are:
Hydroxylamine hydrochloride, 5470-11-1, Hydroxylamine HCl, Hydroxylammonium chloride, Oxammonium hydrochloride, Hydroxyamine hydrochloride, HYDROXYLAMINE, HYDROCHLORIDE, Hydroxylamine chloride (1:1), CHEBI:5807, hydroxyamine HCl, Oxammonium HCI, hydroxylamine.HCl, Hydroxylamine-HCl, hydroxyl amine HCl, NH2OH hydrochloride, hydroxyamine HCl salt, HONH2HCl, hydroxylamine HCl salt, hydroxylamine-HCl salt, amino alcohol HCl salt, H2NOH HCl, H2NOH-HCl, H2NOH.HCl, HCl H2NOH, HONH2-HCl, HONH2.HCl, hydroxylaminehydrochlorid, hydroxylaminhydrochloride, NH2OH HCl, NH2OH-HCl, NH2OH.HCl, PubChem23590, ACMC-1ARAV, hydroxylaminehydrochloride, N-hydroxyamine HCl salt, H2N-OH.HCl, hydoxylamine hydrochloride, hydroxilamine hyrochloride, hydroxyamine-hydrochloride, hydroxylamin hydrochloride, hydroxylamin-hydrochloride, hydroxylamine hydochloride, hydroxylamine hydrochlorde, hydroxylamine hydrochlorid, hydroxylamine hydrocloride, hydroxylamine hyrochloride, hydroxylamme hydrochloride, NH2-OH.HCl, AC1Q3DHK, Hydroxyamine.hydrochloride, Hyroxylamine hydrochloride, hydroxilamine hydrochloride, HYDROXYLAMINE, ACS, hydroxylamine-hydrochloride, hydroxylamine.hydrochloride, DSSTox_CID_5425, hydroxy-amine hydrochloride, Hydroxylarnine hydrochloride, hydroxy lamine hydrochloride, hydroxyl amine hydrochloride, hydroxyl amine-hydrochloride, hydroxyl-amine hydrochloride, Hydroxylamine. hydrochloride, AC1L9EE5, WLN: ZQ &GH, DSSTox_RID_77781, N-hydroxylamine hydrochloride, DSSTox_GSID_25425, hydroxyamine monohydrochloride, hydroxyl amine hydro chloride, Hydroxylamine hydrogenchloride, hydroxyamine hydrogen chloride, hydroxylamine monohydrochloride, KSC492E0J, hydrochloric acid hydroxylamine, hydroxyamine hydrochloride salt, hydroxylamine hydrochloric acid, hydroxylamine hydrogen chloride, hydroxyiamine hydrochloride salt, hydroxylamine hydrochloride salt, DTXSID7025425, CTK3J2204, hydroxylamine monohydrogen chloride, MolPort-003-926-920, N-hydroxylamine hydrochloride salt, WTDHULULXKLSOZ-UHFFFAOYSA-N, hydroxylamine hydrochloric acid salt, KS-00000F9Q, Hydroxylamine hydrochloride, 99.0%, Tox21_202970, Tox21_500637, ANW-13987, LS-213, MFCD00051089, NSC-26250, AKOS015848378, CCG-221941, LP00637, RP18291, RTR-019339, NCGC00094004-01, NCGC00260516-01, NCGC00261322-01, AN-19098, BP-12832, Hydroxylamine hydrochloride, AR, >=99%, Hydroxylamine hydrochloride, LR, >=98%, SC-25787, CAS-5470-11-1, AB1003130, KB-254248, TR-019339, CS-0015850, EU-0100637, FT-0627151, C11598, H 9876, Hydroxylamine hydrochloride, ACS reagent, 98.0%, Hydroxylamine hydrochloride, ReagentPlus(R), 99%, SR-01000075156, J-521474, SR-01000075156-1, I14-16582, Hydroxylamine hydrochloride, 99.995% trace metals basis, Hydroxylamine hydrochloride, 99.999% trace metals basis, Hydroxylamine hydrochloride, p.a., ACS reagent, 99.0%, Hydroxylamine hydrochloride, SAJ first grade, >=95.0%, Hydroxylamine hydrochloride, >=99.9995% (metals basis), Hydroxylamine hydrochloride, JIS special grade, >=98.0%, Hydroxylamine hydrochloride, purum p.a., >=98.0% (RT), Hydroxylamine hydrochloride, puriss. p.a., ACS reagent, >=99.0% (RT), Hydroxylamine hydrochloride, >=97.0%, suitable for determination of toxic metals, Hydroxylamine hydrochloride, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.0%, Hydroxylamine hydrochloride, ACS, 96.0% min. 100g

ID: 2510

chemical graph of compound 2510



InChIKey: WTDRDQBEARUVNC-LURJTMIESA-N
SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6047
synonyms found at PubChem are:
levodopa, L-dopa, 59-92-7, Dopar, 3,4-dihydroxy-L-phenylalanine, 3-Hydroxy-L-tyrosine, Larodopa, Bendopa, Levopa, Cidandopa, Insulamina, Maipedopa, Dopaidan, Dopalina, Dopasol, Eldopal, Eldopar, Pardopa, Prodopa, Syndopa, (-)-Dopa, Dihydroxy-L-phenylalanine, Helfo-Dopa, Brocadopa, Dopaflex, Deadopa, Dopal-fher, 3,4-Dihydroxyphenylalanine, 3-(3,4-Dihydroxyphenyl)-L-alanine, Doparkine, Dopaston, Dopastral, Eldopatec, Eurodopa, Doparl, Doprin, Veldopa, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, Levedopa, Levodopum, L-o-Hydroxytyrosine, Dopa, Ledopa, (-)-3-(3,4-Dihydroxyphenyl)-L-alanine, L-3,4-Dihydroxyphenylalanine, L-Tyrosine, 3-hydroxy-, 3,4-Dihydroxyphenyl-L-alanine, Dopaston SE, beta-(3,4-Dihydroxyphenyl)-L-alanine, L-(o-Dihydroxyphenyl)alanine, L-(-)-Dopa, L-beta-(3,4-Dihydroxyphenyl)alanine, Biodopa, Cerepap, Sobiodopa, Weldopa, Parda, L-Dihydroxyphenylalanine, Helfo DOPA, Ro 4-6316, beta-(3,4-Dihydroxyphenyl)alanine, L-3-Hydroxytyrosine, L-3-(3,4-Dihydroxyphenyl)alanine, Tyrosine, 3-hydroxy-, Laradopa, Levodopum [INN-Latin], L-O-Dihydroxyphenylalanine, alanine, 3-(3,4-dihydroxyphenyl)-, L-, component of Sinemet, CCRIS 3766, Dopar (TN), (S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, CHEBI:15765, HSDB 3348, beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine, L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine, UNII-46627O600J, 3,4-Dihydroxyphenylalanine (VAN), Alanine, 3-(3,4-dihydroxyphenyl)-, (-)-, L(-)-Dopa, (-)-(3,4-Dihydroxyphenyl)alanine, EINECS 200-445-2, dihydroxyphenylalanine, NSC 118381, L-3,4-Dihydrophenylalanine, L-.beta.-(3,4-Dihydroxyphenyl)alanine, CHEMBL1009, .beta.-(3,4-Dihydroxyphenyl)-L-alanine, beta-(3,4-Dihydroxyphenyl)-alpha-alanine, L-(3,4-Dihydroxyphenyl)alanine, CVT-301, WTDRDQBEARUVNC-LURJTMIESA-N, NSC118381, .beta.-(3,4-Dihydroxyphenyl)alanine, C9H11NO4, CAS-59-92-7, NCGC00016270-04, L-(3,4-Dihydroxyphenyl)-.alpha.-alanine, 46627O600J, 587-45-1, BDBM50130192, L Dopa, WLN: QVYZ1R CQ DQ, SR-01000075384, Dopastone, Dopicar, Inbrija, Prolopa, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate, IV Levodopa, Levodopa [USAN:INN:BAN:JAN], Prestwick_185, Levodopa (Sinemet), L-DOPA; Levodopa, Madopa (Salt/Mix), Levodopa [USAN:USP:INN:BAN:JAN], Spectrum_000454, AC1L1LOR, Prestwick0_000017, Prestwick1_000017, Prestwick2_000017, Prestwick3_000017, Spectrum2_000496, Spectrum4_000539, Spectrum5_001899, Lopac-D-9628, Levodopa (JP15/USP), DSSTox_CID_3209, bmse000322, D08HVR, Epitope ID:150927, AC1Q4U7F, 3, 4-Dihydroxyphenylalanine, Alanine,4-dihydroxyphenyl)-, DSSTox_RID_76926, DSSTox_GSID_23209, Lopac0_000454, SCHEMBL22655, BSPBio_000053, BSPBio_002354, KBioGR_001177, KBioSS_000934, L-4-5-Dihydroxyphenylalanine, MLS000028514, BIDD:GT0158, DivK1c_000452, L-Dopa, L-3-Hydroxytyrosine, SPECTRUM2300205, Levodopa (JP17/USP/INN), SPBio_000391, SPBio_001974, BPBio1_000059, GTPL3639, (S)-3,4-dihydroxyphenylalanine, b-(3,4-Dihydroxyphenyl)alanine, DTXSID9023209, WLN: QVYZ1R CQ DQ -L, 3, 4-Dihydroxy-L-phenylalanine, BDBM60928, CTK1H2187, HMS501G14, KBio1_000452, KBio2_000934, KBio2_003502, KBio2_006070, Alanine,4-dihydroxyphenyl)-, L-, L-(3, 4-Dihydroxyphenyl)alanine, MolPort-000-856-937, NINDS_000452, HMS1568C15, HMS1922J14, HMS2090O08, HMS2093N04, HMS2095C15, HMS2230B04, HMS3261K10, HMS3712C15, Pharmakon1600-02300205, ZINC895199, HY-N0304, b-(3,4-Dihydroxyphenyl)-L-alanine, Tox21_110338, Tox21_500454, ANW-33396, CCG-39571, KM0355, L-3-(3,4-dihydroxy-phenyl)alanine, L-3-(3,4-dihydroxyphenyl)-Alanine, LS-255, MFCD00002598, NSC759573, PDSP1_001541, PDSP2_001525, s1726, SBB017533, Alanine, 3-(3,4-dihydroxyphenyl)-, Alanine,4-dihydroxyphenyl)-, (-)-, AKOS010396267, b-(3,4-Dihydroxyphenyl)-a-L-alanine, L-b-(3,4-Dihydroxyphenyl)-a-alanine, .beta.-(3, 4-Dihydroxyphenyl)alanine, AC-8432, AM82124, AN-1108, CS-1945, DB01235, LP00454, MCULE-4743781842, NSC-118381, NSC-759573, RTR-020755, SDCCGMLS-0066924.P001, VA11170, IDI1_000452, NCGC00015384-01, NCGC00016270-01, NCGC00016270-06, NCGC00016270-07, NCGC00016270-09, NCGC00016270-10, NCGC00093869-04, NCGC00261139-01, AJ-24154, AS-13287, BC677906, BP-12850, H813, KB-28327, SC-10704, SMR000058312, ST086623, SBI-0050439.P003, AB0013279, AB1009504, L-(3, 4-Dihydroxyphenyl)-.alpha.-alanine, TR-020755, D0600, D9628, EU-0100454, FT-0603250, N1648, 59L927, Alanine, 3-(3, 4-dihydroxyphenyl)-, (-)-, C00355, D 9628, D00059, J10404, 13173-EP2269989A1, 13173-EP2277876A1, 13173-EP2277882A1, 13173-EP2281559A1, 13173-EP2281815A1, 13173-EP2292614A1, 13173-EP2295412A1, 13173-EP2295413A1, 13173-EP2295439A1, 13173-EP2298731A1, 13173-EP2301933A1, 13173-EP2301934A1, 13173-EP2305633A1, 13173-EP2305640A2, 13173-EP2308867A2, 13173-EP2308870A2, 13173-EP2311827A1, 13173-EP2311837A1, 13173-EP2314571A2, 13173-EP2316470A2, 13173-EP2316834A1, 21660-EP2272832A1, 21660-EP2275420A1, 21660-EP2281559A1, 21660-EP2301934A1, 21660-EP2314571A2, 21920-EP2295410A1, 21920-EP2301939A1, 21920-EP2314571A2, 3,4-Dihydroxy-L-phenylalanine, >=98% (TLC), AB00052418-06, AB00052418-07, AB00052418_08, AB00052418_09, Q-201294, SR-01000075384-1, SR-01000075384-4, SR-01000075384-6, SR-01000075384-7, I01-10387, Levodopa (optimized formulation, Parkinson's disease), More effective levodopa (Parkinson's disease), Orion, (S)-2-Amino-3-(3,4-dihydroxy-phenyl)-propionic acid, F0347-4695, Levodopa, British Pharmacopoeia (BP) Reference Standard, Levodopa, European Pharmacopoeia (EP) Reference Standard, Z1762772338, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acidL-dopa, UNII-QI9C343R60 component WTDRDQBEARUVNC-LURJTMIESA-N, 1E83F927-C221-46AA-B90A-81B33C5F3868, 3,4-Dihydroxy-L-phenylalanine, Vetec(TM) reagent grade, 98%, Levodopa (optimized formulation, Parkinson's disease), Orion, Levodopa, United States Pharmacopeia (USP) Reference Standard, L-3-(3,4-Dihydroxyphenyl)alanine（L-DOPA ）, 3-(3,4-Dihydroxyphenyl)-L-alanine; L-3-Hydroxytyrosine; L-DOPA; Levodopa, Levodopa, Pharmaceutical Secondary Standard; Certified Reference Material, 23734-74-9, 25525-15-9, 34241-25-3, 72572-99-7, 72573-00-3, 88250-23-1, 90638-38-3, (2S)-2-ammonio-3-(3,4-dihydroxyphenyl)propanoate, (2S)-2-azaniumyl-3-(3,4-dihydroxyphenyl)propanoate, L-dopa zwitterion, L-dihydroxy-phenylalanine, AC1ODZ2Q, CHEBI:57504, ZB014991, A832543, (2S)-2-azaniumyl-3-[3,4-bis(oxidanyl)phenyl]propanoate

ID: 2511

chemical graph of compound 2511



InChIKey: WTJXVDPDEQKTCV-VQAITOIOSA-N
SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 54685925
synonyms found at PubChem are:
MINOCYCLINE HYDROCHLORIDE, 13614-98-7, Minocycline HCl, Minomycin, Minocycline chloride, Arestin, Minocin, Vectrin, Minomax, Periocline, Tri-mino, Dynacin, Klinomycin, Minocycline (hydrochloride), Solodyn, Mynocine hydrochloride, Tri-minocycline, UNII-0020414E5U, EINECS 237-099-7, Minocycline, Hydrochloride, Minocycline hydrochloride (internal use), 0020414E5U, Minocin (TN), DSSTox_CID_24545, DSSTox_RID_80306, DSSTox_GSID_44545, (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride, 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,12aalpha))-, 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, C23H28ClN3O7, 7-Dimethylamino-6-demethyl-6-deoxytetracycline, HCl, Acnez, Ximino, Minomycin chloride, CHEBI:50697, (4S-(4alpha,4aalpha,5aalpha,12aalpha))-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride, [4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride, [4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride;[4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride, Lederderm, Mynocine, Minocycline, HCl, NCGC00096006-01, Prestwick_626, Arestin (TN), Dynacin (TN), Solodyn (TN), Minocycline hydrochloride [USP:JAN], Minocycline hydrochloride [USAN:JAN], AC1NQY0N, AC1NSG07, SCHEMBL2537, CAS-13614-98-7, MLS002548863, C23H27N3O7.HCl, SPECTRUM1500414, FXFM-244, CHEMBL1200881, DTXSID8044545, GLMUAFMGXXHGLU-VQAITOIOSA-N, MolPort-003-666-235, MolPort-042-652-589, HMS1568P12, Pharmakon1600-01500414, 10118-90-8 (Parent), BCP06597, KS-00000XT8, Tox21_111250, Tox21_113183, Tox21_301590, 10118-90-8 (base), CCG-40107, MFCD00083669, NSC757120, s4226, Minocycline hydrochloride, crystalline, AKOS015951312, Minocycline hydrochloride (JP17/USP), Tox21_111250_1, CS-1256, NC00460, NSC-757120, NCGC00178854-03, NCGC00255988-01, 11006-27-2, AC-22362, BC207859, HY-17412, LS-91518, LS-93852, S051, SC-19210, SMR001906766, AB1009463, KB-274624, FT-0082736, FT-0601821, M2288, ST24034766, D00850, J10198, W-5076, 614M987, Q-201407, Minocycline hydrochloride, Antibiotic for Culture Media Use Only, Minocycline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Minocycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Minocycline hydrochloride, United States Pharmacopeia (USP) Reference Standard, (2E,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride, (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride, (4S,12aS,4aS,5aR)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide Hydrochloride, [4S-(4?,4a?,5a?,12a?)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, [4S-(4|A,4a|A,5a|A,12a|A)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydro-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride, [4S-(4|A,4a|A,5a|A,12a|A)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride, [4S-(4a,4aa,5aa,12aa)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, 1071702-75-4, 1236362-29-0, 150231-24-6, 2-Naphthacenecarboxamide, 4,7- bis(dimethylamino)-1,4,4a,5,5a,6,11,12a- octahydro-3,10,12,12a-tetrahydroxy-1,11dioxo-, monohydrochloride, [4S-(4alpha,4aalpha,5aalpha,12aalpha)], 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, monohydrochloride, SCHEMBL11297721

ID: 2512

chemical graph of compound 2512



InChIKey: WTXBRZCVLDTWLP-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1F)C=C(N2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1820
synonyms found at PubChem are:
5-Fluoroindole-2-carboxylic acid, 399-76-8, 5-Fluoro-1H-indole-2-carboxylic acid, 2-Carboxy-5-fluoroindole, 1H-Indole-2-carboxylic acid, 5-fluoro-, CHEMBL23507, MLS000080089, WTXBRZCVLDTWLP-UHFFFAOYSA-N, SMR000037735, Spectrum_001495, EINECS 206-919-5, PubChem1683, SpecPlus_000678, Opera_ID_1340, Spectrum2_001469, Spectrum3_001043, Spectrum4_001182, Spectrum5_001733, ACMC-209j9k, D06BFH, AC1L1CB9, AC1Q4NE3, AC1Q73TI, AC1Q73TJ, cid_1820, Lopac-265128, Lopac0_000071, Oprea1_012690, 5-F-ICA, BSPBio_002566, KBioGR_001843, KBioSS_001975, KSC224O4B, MLS000069465, MLS001201811, DivK1c_006774, SCHEMBL209759, SPECTRUM1502092, SPBio_001397, 2-Carboxy-5-fluoro-1H-indole, 5-fluorindole-2-carboxylic acid, CTK1C4740, KBio1_001718, KBio2_001975, KBio2_004543, KBio2_007111, KBio3_001786, TIMTEC-BB SBB010058, ZINC83028, AKOS JY2082860, DTXSID10192945, CHEBI:111276, MolPort-000-145-668, OTAVA-BB 1056235, 5-fluoro 2 indole carboxylic acid, 5-fluoro indole-2-carboxylic acid, 5-fluoro-2-indole carboxylic acid, AM973, HMS2233A14, HMS3260O03, ACT02473, KS-000005CY, Tox21_500071, 5fluoro-1H-indole-2-carboxylic acid, ANW-29238, BBL027533, BDBM50009126, CCG-39179, CF-579, LABOTEST-BB LT00452936, MFCD00005612, SBB010058, STK296660, AKOS000139135, AC-9839, AS02105, CM13610, CS-W017282, FS-1258, LP00071, LS20431, MCULE-7105968907, RP03141, RTR-015945, TRA0000228, VI30046, 1H-Indole-2-carboxylicacid, 5-fluoro-, 5-Fluoroindole-2-carboxylic acid, 99%, NCGC00014995-01, NCGC00014995-02, NCGC00014995-03, NCGC00014995-04, NCGC00014995-05, NCGC00014995-06, NCGC00014995-07, NCGC00014995-08, NCGC00014995-09, NCGC00014995-10, NCGC00022203-04, NCGC00022203-05, NCGC00022203-06, NCGC00022203-07, NCGC00260756-01, 5-Fluoro-1H-indole-2-carboxylic acid #, AJ-10624, AN-44727, BR-30506, KB-43295, N496, SC-46131, AB0015822, AB1005656, DB-031611, KB-245885, ST2406261, TL8002889, TR-015945, BB 0248945, EU-0100071, F0716, FT-0620422, ST45136260, EN300-28441, A22124, S-3777, AB00053198-15, 399F768, SR-01000003027, SR-01000003027-2, BRD-K55273157-001-02-9, BRD-K55273157-001-13-6, Z235348085, 5-Fluoro-1h-indole-2-carboxylic acid; 2-Carboxy-5-fluoroindole

ID: 2513

chemical graph of compound 2513



InChIKey: WTYSXBKKVNOOIX-JTGCGUAKSA-N
SMILES: C1[C@@H]([C@@H]([C@H]([C@H]1F)/C=C/[C@@H](C2CC3=CC=CC=C3C2)O)C/C=C\CCCC(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5311238
synonyms found at PubChem are:
AL-8810, AL 8810, UNII-12QE8J6004, AL8810, 12QE8J6004, 246246-19-5, (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid, SR-01000075674, AC1NSKA5, D05VOG, GTPL1956, CHEMBL1332680, AOB5959, MolPort-027-640-944, HMS3261O18, HMS3648F14, (5Z, 13E)-(9S,11S,15R)-9,15,Dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19,20,pentanor-5,13-prostadienoic acid, ZINC3981322, Tox21_500478, CCG-204142, LP00478, NCGC00186007-01, NCGC00261163-01, AL-8810, >=98% (HPLC), solid, AL-881011, EU-0100046, A 3846, J-015605, SR-01000075674-1, SR-01000075674-4, (5Z,13E)-(9S,11S,15R)-9,15,DIHYDROXY-11-FLUORO-15-(2-INDANYL)-16,17,18,19,20,PENTANOR-5,13-PROSTADIENOIC ACID, 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propenyl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-

ID: 2514

chemical graph of compound 2514



InChIKey: WTZRHZRMLYNBRM-UHFFFAOYSA-N
SMILES: C1CC1(C(=O)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11018932
synonyms found at PubChem are:
WTZRHZRMLYNBRM-UHFFFAOYSA-N, 1-Carboxycyclopropanaminium chloride, 1-aminocyclopropanecarboxylate hydrochloride, 68781-13-5, 1-Aminocyclopropanecarboxylic acid hydrochloride, 1-aminocyclopropane-1-carboxylic acid hydrochloride, 1-Amino-cyclopropane-1-carboxylic acid hydrochloride, 1-AMINOCYCLOPROPANECARBOXYLIC ACID HCL, MFCD00012545, C4H8ClNO2, 1-Amino-cyclopropane-1-carboxylic acid, HCl, Cyclopropanecarboxylic acid, 1-amino-, hydrochloride, 1-aminocyclopropanecarboxylic acid, chloride, ACPC-HCL, PubChem13872, AC1Q3CVR, EU-0100072, KSC352Q0J, MLS000859912, SCHEMBL1320265, CHEMBL1255660, CTK2F2804, DTXSID10474677, MolPort-003-940-008, ACT04355, KS-00000XS4, Tox21_500072, ANW-46130, SBB059531, AKOS015847653, AC-1835, CA-1653, CCG-221376, LP00072, LS41412, MCULE-8718774934, RP00145, RTC-071043, VZ21137, NCGC00093581-01, NCGC00260757-01, AN-14568, AS-18894, BC205080, KB-64865, SC-21274, SMR000326773, AB0030885, DB-005077, TC-071043, 4CH-011951, FT-0600511, ST24021211, ST51044491, X3152, EN300-29759, A 0430, W-2960, 1-amino-1-cyclopropanecarboxylic acid hydrochlori, 781A135, A836248, SR-01000075654, 1-amino-1-cyclopropanecarboxylic acid hydrochloride, 1-azanylcyclopropane-1-carboxylic acid hydrochloride, I04-0447, J-504204, SR-01000075654-1, 1-Aminocyclopropanecarboxylic acid hydrochloride, >=98%, Z235362779, Cyclopropanecarboxylicacid, 1-amino-, hydrochloride (1:1)

ID: 2515

chemical graph of compound 2515



InChIKey: WUFRNEJYZWHXLC-CTERPIQNSA-M
SMILES: C[C@H]1[C@@H](C[C@H](O1)C[N+](C)(C)C)O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 16817
synonyms found at PubChem are:
(+)-Muscarine chloride, MUSCARINE CHLORIDE, UNII-U700RQ3UBQ, L-(+)-Muscarine chloride, HSDB 3515, EINECS 218-963-2, U700RQ3UBQ, 2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, chloride, (2S-(2alpha,4beta,5alpha))-, 2303-35-7, CHEMBL1255785, (2S-(2alpha,4beta,5alpha))-(Tetrahydro-4-hydroxy-5-tetramethylfurfuryl)trimethylammonium chloride, (+/-)-Muscarine chloride, 300-54-9, SR-01000076018, DL-Muscarine chloride, (y)-Muscarine chloride, (?)-Muscarine chloride, (+-)-Muscarine chloride, AC1L28QL, SCHEMBL2821768, MolPort-039-033-245, HMS3262L05, Tox21_500852, AKOS030230545, CCG-208481, LP00852, NCGC00094180-01, NCGC00261537-01, LS-93734, ( inverted question mark)-Muscarine chloride, EU-0100852, M-104, J-014953, SR-01000076018-1, [(2S,4R,5S)-4-hydroxy-5-methyloxolan-2-yl]methyl-trimethylazanium chloride, Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride, (+)-(2S,4R,5S)-Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride, (+)-Tetrahydro-4|A-hydroxy-N,N,N,5|A-tetramethyl-2|A-furanmethanaminium chloride, 2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, chloride, (2alpha,4beta,5alpha)-(+-)-, 4293-78-1

ID: 2516

chemical graph of compound 2516



InChIKey: WUILNKCFCLNXOK-CFBAGHHKSA-N
SMILES: CC(=CCC/C(=C/CC/C(=C/CSC1=CC=CC=C1C(=O)O)/C)/C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5469318
synonyms found at PubChem are:
Salirasib, 162520-00-5, Farnesylthiosalicylic acid, S-Farnesylthiosalicylic acid, UNII-MZH0OM550M, FTS, Farnesylthiosalicyclic acid, MZH0OM550M, CHEMBL23293, 2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylbenzoic acid, 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic Acid, 2-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienylthio)benzoic acid, 2-(((2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl)sulfanyl)benzoic acid, Benzoic acid, 2-(((2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl)thio)-, Salirasib [USAN], Salirasib [USAN:INN], S-trans, FTS, Thyreos, Farnesylthiosalicylate, S-trans,trans-farnesylthiosalicylic acid, Ras antagonists, Thyreos, Salirasib (INN/USAN), Lopac-F-8175, D00KTV, D05YQY, AC1NV5Y3, Lopac0_000517, MLS006010835, Trans-farnesylthiosalicylicacid, GTPL6281, FTS (oral, cancer), Concordia, Salirasib, >=98% (HPLC), Th-101, MolPort-003-847-356, WUILNKCFCLNXOK-CFBAGHHKSA-N, KD032, BCP27978, EX-A1170, ONO-7056, Ras-inhibitors (cancer), Concordia, trans,trans-Farnesylthiobenzoic acid, ZINC1650377, FTS (oral, cancer), Concordia/Ono, 2030AH, BDBM50034278, IN2128, KD-032, NSC685986, s7684, AKOS024458453, CCG-204607, CS-0681, DB12681, NSC-685986, trans,trans Farnesyl Thiosalicylic Acid, NCGC00015448-01, NCGC00015448-02, NCGC00015448-03, NCGC00093912-01, NCGC00093912-02, AK186909, BC600693, HY-14754, SMR004701762, LS-186975, LS-187617, EU-0100517, D08995, F 8175, W-5109, Farnesylthiosalicylic acid, >98% (HPLC), solid, SR-01000075885, J-009946, SR-01000075885-1, Farnesylthiosalicyclic acid (oral, cancer), Concordia, 2-[(3,7,11-Trimethyl-2,6,10-dodecatrienyl)thio]benzoic acid, (E,E)-2-[(3,7,11-Trimethyl-2,6,10-dodecatrienyl)thio]benzoic Acid, 2-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylsulfanyl)-benzoic acid, 166445-40-5

ID: 2517

chemical graph of compound 2517



InChIKey: WURBVZBTWMNKQT-UHFFFAOYSA-N
SMILES: CC(C)(C)C(=O)C(N1C=NC=N1)OC2=CC=C(C=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 39385
synonyms found at PubChem are:
TRIADIMEFON, 43121-43-3, Bayleton, Azocene, Triadimefone, Amiral, Fenxiunin, Haleton, Acizol, Adifon, Mighty, Miltek, Strike, Typhon, Bayleton triple, Nurex, Reach, Rofon, Bayleton Total, Diametom B, Bayleton BM, Bayleton CF, Bayleton BM gel, Otria 25, Caswell No. 862AA, Tenor, Triadimefon [BSI:ISO], MEB 6447, Triadimefone [ISO-French], Bay MEB 6447, NSC 303303, BAY-MEB-6447, HSDB 6857, BAY 6681 F, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one, 2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-, EINECS 256-103-8, EPA Pesticide Chemical Code 109901, BRN 0619231, 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-one, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one, 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone, CHEMBL520897, BAY 6681F, CHEBI:84002, WURBVZBTWMNKQT-UHFFFAOYSA-N, 1H-1,2,4-Triazole, 1-((tert-butylcarbonyl-4-chlorophenoxy)methyl)-, 1-(1,2,4-Triazoyl-1)-1-(4-chloro-phenoxy)-3,3-dimethylbutanone, 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butanone, 2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-, W-106246, 93779-51-2, Triadimeform, Tidifon, Bayleton special, Bayleton 5, Tartan (fungicide), Bayleton 250 EC, ACMC-20lms9, Spectrum2_001707, Spectrum3_001962, DSSTox_CID_3897, AC1L21MS, DSSTox_RID_77222, DSSTox_GSID_23897, Oprea1_598872, Oprea1_827146, SCHEMBL21204, BSPBio_003562, 5-26-01-00123 (Beilstein Handbook Reference), MLS002695917, SPECTRUM1505307, SPBio_001694, BAY-MEB 6447, IFLab1_000075, Triadimefon, analytical standard, DTXSID3023897, CTK4I7039, KBio3_002907, MolPort-001-886-762, HMS1412D09, HMS3089A16, Tox21_300886, BDBM50295561, CCG-39446, NSC303303, STL281794, AKOS000583075, AKOS016050579, AGR0000046, MCULE-3287013666, NSC-303303, ACM43121433, IDI1_008294, NCGC00094573-01, NCGC00094573-02, NCGC00094573-03, NCGC00094573-04, NCGC00094573-05, NCGC00094573-06, NCGC00094573-07, NCGC00254790-01, Triadimefon 10 microg/mL in Cyclohexane, AC-12579, BAS 00654795, KB-09009, LS-46663, O539, SMR000778089, Triadimefon 10 microg/mL in Acetonitrile, AB1004877, CAS-43121-43-3, TL8003039, EU-0066688, FT-0639834, C11156, Triadimefon, PESTANAL(R), analytical standard, 121T433, C-36799, SR-01000388703, 2-Butanone,3-dimethyl-1-(1,2,4-triazol-1-yl)-, I06-1156, SR-01000388703-1, BRD-A39506880-001-02-9, 1-(4-Chlorophenoxy)-3,2,4-triazol-1-yl)-butan-2-one, 2-Butanone,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-, Triadimefon Solution, 10 mg/L, 10 ml (RM, ISO GUIDE 34), 1-(4-Chloro-phenoxy)-3,3-dimethyl-1-[1,2,4]triazol-1-yl-butan-2-one, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl) butan-2-one, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1h-1,2,4-triazol-1-yl)-butan-2-one, 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazole -1-yl)-2-butanone, 2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)- (9CI), 1135441-18-7, 119143-30-5, 148227-32-1, 72650-40-9

ID: 2518

chemical graph of compound 2518



InChIKey: WUWDLXZGHZSWQZ-WQLSENKSSA-N
SMILES: CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5329098
synonyms found at PubChem are:
Semaxanib, SU5416, SU 5416, Semaxinib, 204005-46-9, 194413-58-6, Semoxind, Semaxanib (SU5416), SU-5416, Semaxnib, TSU 16, UNII-71IA9S35AJ, VEGF Receptor 2 Kinase Inhibitor III, TSU-16, (Z)-3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)indolin-2-one, Semaxanib (USAN/INN), (Z)-SU 5416, methylene]-2H-indol-2-one, VEGFR2 Kinase Inhibitor III, 71IA9S35AJ, CHEMBL276711, 3-(1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene)-2-oxo-2,3-dihydroindole, NSC-696819, 3-[(2,4-Dimethylpyrrol-5-yl)methylidene]-indolin-2-one, 3-((Z)-(3,5-Dimethylpyrrol-2-yl)methylene)-2-indolinone, 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one, H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-, S 8442, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one, 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl), 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]indolin-2-one, InSolution™ VEGF Receptor 2 Kinase Inhibitor III, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one, (3Z)-3-[(3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLIDENE]-2,3-DIHYDRO-1H-INDOL-2-ONE, Semaxanib(SU5416), SMR000568416, SR-01000076044, Semaxanib [USAN:INN], Sugen 5416, Romiplostim, Z-Semaxanib, NCGC00094381-03, NSC 696819, 2x2m, D01PZD, D04ADG, D0QY0V, SCHEMBL8190, Lopac0_001110, SCHEMBL19571, MLS001074896, MLS001332519, MLS001332520, 3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one, AC1NS627, BDBM4810, GTPL5056, QCR-86, CHEBI:91083, cid_5329098, AOB6828, MolPort-003-959-606, SIBNPBQTUXWRMZ-ZSOIEALJSA-N, WUWDLXZGHZSWQZ-WQLSENKSSA-N, HMS2234L12, HMS3229O13, HMS3263M22, HMS3268J13, HMS3648O12, BCP06068, Tox21 111271, Tox21_501110, 2033AH, 2712AH, BS0306, HSCI1_000303, MFCD01940922, NSC696819, s2845, SU5146, ZINC12410091, AKOS015994557, AN-3643, CCG-205186, CS-1225, DB06436, ES-0010, LP01110, NCGC00094381-01, NCGC00094381-02, NCGC00094381-04, NCGC00094381-05, NCGC00261795-01, AK174866, AK174898, BC600544, DA-43377, HY-10374, LS-83886, QC-11357, SC-96714, AB0094985, LS-193151, RT-016226, EU-0101110, D05819, W-5403, 2H-Indol-2-one,5-dimethyl-2-pyrrolyl)methylene]-, J-013281, SR-01000076044-2, SR-01000076044-8, BRD-K63504947-001-05-5, 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one, 3-[(3,5-Dimethyl-2H-pyrrol-2-ylidene)methyl]-1H-indol-2-ol, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]indolin-2-one, 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro- 2H-indol-2-one, 3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylene]-1,3-dihydro-2h-indol-2-one, 2H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-, (3Z)-, 2H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-, (Z)-, 2H-Indol-2-one, 3-(3,5-dimethyl-1H-pyrrol-2-yl)methylene)- 1,3-dihydro-, (Z)-, 3-[1-(3,5-dimethyl-1h-pyrrol-2-yl)-meth-(z)-ylidene]-2-oxo-2,3-dihydro-indole, 267639-76-9

ID: 2519

chemical graph of compound 2519



InChIKey: WUYMIKDBRCCYGE-BTJKTKAUSA-N
SMILES: C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11211984
synonyms found at PubChem are:
Thioperamide maleate, 106243-16-7, 148440-81-7, SR-01000075293, Thioperamide.maleate, EU-0101214, MLS000860051, CHEMBL1256702, SCHEMBL17908154, AOB5573, C15H24N4S.C4H4O4, MolPort-003-983-698, MolPort-009-019-463, WUYMIKDBRCCYGE-BTJKTKAUSA-N, HMS2230A09, HMS3263D10, HMS3714J06, Tox21_501214, 2073AH, BN0519, CCG-220922, CCG-222518, LP01214, NCGC00094460-01, NCGC00261899-01, SMR000326909, T-123, J-008468, SR-01000075293-1, SR-01000075293-3, SR-01000075293-6, N-cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide maleate

ID: 2520

chemical graph of compound 2520



InChIKey: WVKDAMAQNQRJFP-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=COC3=C(C2=O)C(=CC(=C3OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708795
synonyms found at PubChem are:
ISOTECTORIGENIN, 7-METHYL ETHER, KBio2_003579, Spectrum_000531, SpecPlus_000846, AC1O8FPK, Spectrum2_000217, Spectrum3_000167, Spectrum4_001490, Spectrum5_000199, BSPBio_001633, KBioGR_002099, KBioSS_001011, SPECTRUM200139, DivK1c_006942, SPBio_000233, CHEMBL1488728, SCHEMBL12998491, KBio1_001886, KBio2_001011, KBio2_006147, KBio3_001133, CCG-39779, SDCCGMLS-0066437.P001, NCGC00095471-01, NCGC00095471-02, NCGC00179134-01, SR-05000002587, SR-05000002587-1, 5-hydroxy-7,8-dimethoxy-3-(4-methoxyphenyl)chromen-4-one

ID: 2521

chemical graph of compound 2521



InChIKey: WVMBPWMAQDVZCM-UHFFFAOYSA-N
SMILES: CNC1=CC=CC=C1C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 67069
synonyms found at PubChem are:
N-Methylanthranilic acid, 2-(Methylamino)benzoic acid, 119-68-6, N-Methyl-2-aminobenzoic acid, Benzoic acid, 2-(methylamino)-, N-Methyl-o-aminobenzoic acid, o-(Methylamino)benzoic acid, Anthranilic acid, N-methyl-, 2-Methylamino-benzoic acid, Kyselina N-methylanthranilova, UNII-VPB2514IUJ, Kyselina N-methylanthranilova [Czech], Kyselina 2-methylaminobenzoova, NSC 3782, N-methyl-anthranilic acid, EINECS 204-343-9, N-Methylanthranilate, Kyselina 2-methylaminobenzoova [Czech], BRN 2208135, VPB2514IUJ, 2-(methylamino)-benzoic acid, AI3-05924, CHEBI:16394, WVMBPWMAQDVZCM-UHFFFAOYSA-N, N-methylanthranilic, zlchem 1306, Spectrum_000180, SpecPlus_000945, o-methylaminobenzoic acid, n-methyl anthranilic acid, Spectrum2_001916, Spectrum3_000673, Spectrum4_001637, Spectrum5_000453, timtec-bb sbb006591, WLN: QVR BM1, AC1Q40VU, AC1Q5U9H, ACMC-1C9U2, akos 219-09, akos bbs-00006460, Oprea1_531375, BSPBio_002365, KBioGR_002073, KBioSS_000660, 4-14-00-01015 (Beilstein Handbook Reference), BIDD:GT0295, DivK1c_007041, SCHEMBL130356, SPECTRUM1600964, 2-(n-methylamino)benzoic acid, Anthranilic acid, N-methyl-,, SPBio_001912, 2-(N-methyl)aminobenzoic acid, N-Methylanthranilic acid, 8CI, AC1L26S5, CHEMBL1528955, DTXSID6059491, CTK3J3926, KBio1_001985, KBio2_000660, KBio2_003228, KBio2_005796, KBio3_001585, NSC3782, ZLE0081, MolPort-000-489-697, ZINC270812, NSC-3782, 8073AF, ANW-17364, BBL009790, CCG-38484, MFCD00002424, SBB006591, STK913995, AKOS000120399, BENZOIC ACID,2-(METHYLAMINO)-, MCULE-5834002880, SDCCGMLS-0066851.P001, NCGC00095760-01, NCGC00095760-02, AC-24424, AJ-18716, AS-50014, KB-66978, LS-20544, SC-43927, RT-001772, FT-0708874, M0154, ST24039687, ST50134942, T7339, C03005, AP-065/40180106, SR-05000002383, SR-05000002383-1, W-109440, BRD-K06439119-001-02-3, BRD-K06439119-001-03-1, I01-18201, F1943-0106, 730910-17-5

ID: 2522

chemical graph of compound 2522



InChIKey: WVQBLGZPHOPPFO-UHFFFAOYSA-N
SMILES: CCC1=CC=CC(=C1N(C(C)COC)C(=O)CCl)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4169
synonyms found at PubChem are:
metolachlor, 51218-45-2, Dual, Yibingjiacaoan, Pennant, Codal, Dual Magnum, Dual Triple, Dual II, Ontrack 8E, Dual 720EC, Dual 960 EC, Metelilachlor, Dual 8E, Humextra, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide, Metolachlor technical, Metetilachlor, Caswell No. 188DD, Metolachlore [ISO-French], 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamide, Metolachlor [ANSI:BSI:ISO], HSDB 6706, Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)-, EINECS 257-060-8, CGA 24705, CGA-24705, EPA Pesticide Chemical Code 108801, BRN 2743537, N-(1-Methyl-2-methoxyethyl)-N-chloroacetyl-2-ethyl-6-methylaniline, CHEBI:83645, WVQBLGZPHOPPFO-UHFFFAOYSA-N, 2-Chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)acet-o-toluidide, 2-Chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)-o-acetotoluidine, 2-Ethyl-6-methyl-1-N-(2-methoxy-1-methylethyl)chloroacetanilide, 2-Aethyl-6-methyl-N-(1-methyl-2-methoxyaethyl)-chloracetanilid [German], 2-Chloro-2'-ethyl-N-(2-methoxy-1-methylethyl)-6'-methylacetanilide, Acetamide, 2-chloro-N-(6-ethyl-o-tolyl)-N-(2-methoxy-1-methylethyl)-, DSSTox_CID_2448, N-(2'-Methoxy-1'-methylethyl)-2'-ethyl-6'-methyl-2-chloroacetanilide, Metolachlor, herbicide (C15-H22-N-O2-Cl), 2-Etylo-6-metylo-N-(1'-metylo-2'-metoksyetylo)chloroacetanilid [Polish], alpha-Chlor-6'-aethyl-N-(2-methoxy-1-methylaethyl)-acet-o-toluidin [German], alpha-Chloro-2'-ethyl-6'-methyl-N-(1-methyl-2-methoxyethyl)-acetanilide, DSSTox_RID_76595, DSSTox_GSID_22448, Metolachlor, analytical standard, Metolachlore, o-Acetotoluidide, 2-chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)-, 2-chloro-N-(2-ethyl-6-methyl-phenyl)-N-(2-methoxy-1-methyl-ethyl)acetamide, CAS-51218-45-2, Jindual, Metoken, Pimagral, Bicel, Metolachlor solution, Bicep (Salt/Mix), Turbo (Salt/Mix), CGA-77102, METOLACHOR, Primagram (Salt/Mix), Primextra (Salt/Mix), (aS,5S)-Metolachlor, Spectrum_001833, Metolaclor (Salt/Mix), SpecPlus_000434, Pace 6L (Salt/Mix), Bicep 6L (Salt/Mix), AC1L1HKG, Spectrum2_001885, Spectrum3_000827, Spectrum4_000667, Spectrum5_001966, Dual 25G (Salt/Mix), SCHEMBL21385, BSPBio_002353, CGA-24705, Pennant., KBioGR_001073, KBioSS_002338, SPECTRUM330035, DivK1c_006530, SPBio_001790, CHEMBL1884974, DTXSID4022448, KBio1_001474, KBio2_002335, KBio2_004903, KBio2_007471, KBio3_001853, MolPort-003-665-443, s475, 2-Aethyl-6-methyl-N-(1-methyl-2-methoxyaethyl)-chloracetanilid, 2-Etylo-6-metylo-N-(1'-metylo-2'-metoksyetylo)chloroacetanilid, Tox21_201376, Tox21_300982, alpha-Chlor-6'-aethyl-N-(2-methoxy-1-methylaethyl)-acet-o-toluidin, CCG-39423, LS-163, AKOS015888371, Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-((1S)-2-methoxy-1-methylethyl)-, (N(S))-, Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)-, stereoisomer, Metolachlor 10 microg/mL in Cyclohexane, NCGC00095767-01, NCGC00095767-02, NCGC00095767-03, NCGC00095767-04, NCGC00095767-05, NCGC00095767-06, NCGC00254884-01, NCGC00258927-01, 82535-90-8, AN-30701, AN-41351, Metolachlor 10 microg/mL in Acetonitrile, Metolachlor 100 microg/mL in Cyclohexane, Metolachlor 100 microg/mL in Acetonitrile, AX8140043, KB-230192, FT-0630641, C10953, Metolachlor, PESTANAL(R), analytical standard, 218M452, METOLACHLOR (PESTICIDE/FERTILIZER MIXTURE), BRD-A43135847-001-02-3, I01-10361, 2-chloro-2'-ethyl-6'-methyl-N-(1-methyl-2-methoxyethyl)acetanilide, 2-chloro-2'-ethyl-6'-methyl-N-(1-methyl-2-methoxyethyl)-acetanilide, 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(-2-methoxy-1-methylethyl)acetamide, Metolachlor solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 164201-38-1, 55762-76-0, 63150-68-5, 94449-58-8

ID: 2523

chemical graph of compound 2523



InChIKey: WVTKBKWTSCPRNU-KYJUHHDHSA-N
SMILES: CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 73078
synonyms found at PubChem are:
tetrandrine, 518-34-3, D-Tetrandrine, Tetrandrin, Fanchinine, (+)-Tetrandrine, Sinomenine A, hanjisong, DL-Tetrandine, (S,S)-Tetrandrine, NSC 77037, (+-)-Tetrandine, (S,S)-(+)-Tetrandrine, NSC-77037, Hanfangchin A, d-Tetrandr, UNII-29EX23D5AJ, Isotetrandrine, CCRIS 2705, S-(+)-Tetrandrine, Tetrandrine(Fanchinine), NSC77037, NSC91771, 23495-89-8, CHEBI:49, BRN 0877811, MLS002153946, 29EX23D5AJ, SMR000445630, (1beta)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman, tetradrine, C38H42N2O6, iso-tetrandrine, Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1beta)-, (11S,31S)-16,36,37,54-tetramethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphane, tetramethoxy(dimethyl)[?], SR-01000779899, TETRANDRINE, (DL), DL-Tetandrine, Tetrandrine,(S), NSC 91771, Tranex-18, (+/-)-Tetrandine, Spectrum_000315, (.+-.)-Tetrandrine, SpecPlus_000661, S,S-(+)-Tetrandrine, Tetrandrine (Fanchinine), Tetrandrine - Fanchinine, Prestwick0_000670, Prestwick1_000670, Prestwick2_000670, Prestwick3_000670, Spectrum2_000025, Spectrum3_000659, Spectrum4_000619, Spectrum5_001366, D0AN2Q, D0G4ES, Tetrandrine, Millenia Hope, AC1Q58EO, (1.beta.)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman, CBiol_001914, SCHEMBL20119, BSPBio_000739, BSPBio_001479, BSPBio_002297, KBioGR_000199, KBioGR_001178, KBioSS_000199, KBioSS_000795, 2-27-00-00889 (Beilstein Handbook Reference), MLS000728516, DivK1c_006757, SPECTRUM1504185, SPBio_000089, SPBio_002660, AC1L2J88, BPBio1_000813, CHEMBL176045, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1 beta-berbaman, KBio1_001701, KBio2_000199, KBio2_000795, KBio2_002767, KBio2_003363, KBio2_005335, KBio2_005931, KBio3_000397, KBio3_000398, KBio3_001517, BRD8237, DTXSID10178062, MolPort-000-763-034, WVTKBKWTSCPRNU-KYJUHHDHSA-N, Bio1_000200, Bio1_000689, Bio1_001178, Bio2_000199, Bio2_000679, HMS1361J21, HMS1570E21, HMS1791J21, HMS1989J21, HMS2097E21, HMS2232C06, HMS3402J21, BRD-8237, BBL029400, CCG-38342, HSCI1_000014, NSC-91771, STK801908, ZINC28116057, Tetrandrine, West Virginia University, AKOS004119881, Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)- (9CI), AC-7987, AN-8470, FF-0019, MCULE-2548279289, SDCCGMLS-0066758.P001, IDI1_033949, NCGC00017376-02, NCGC00017376-03, NCGC00017376-04, NCGC00017376-05, NCGC00017376-06, NCGC00017376-10, NCGC00142549-01, NCGC00142549-02, NCGC00142549-03, NCGC00142549-04, NCGC00182717-01, AS-15343, HY-13764, NCI60_041696, NCI60_042029, O972, SC-14047, ST057602, BCP0726000284, AB0016761, LS-148949, AB00513883, CS-0007782, S2403, C09654, W-2768, 518T343, Q-100580, SR-01000779899-5, SR-01000779899-6, SR-01000779899-7, SR-01000779899-9, Tetrandrine, analytical standard, for drug analysis, BRD-K08078237-001-07-3, BRD-K08078237-001-13-1, Tetrandrine, European Pharmacopoeia (EP) Reference Standard, Berbaman,6',7,12-tetramethoxy-2,2'-dimethyl-, (1.beta.)-, Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1-beta)-, Berbaman,6',7,12-trtramethoxy-2,2'-dimethyl-, (1.beta.)-(PM)-, Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(+-)-, Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)-, (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyc lo[22.6.2.2<3,6>.1<8,12>.1<14,18>.0<22,36>.0<27,31>]hexatriaconta-3(33),4,6(34 ),8(35),9,11,18(36),19,21,24,26,31-dodecae, (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyc lo[22.6.2.2<3,6>.1<8,12>.1<14,18>.0<22,36>.0<27,31>]hexatriaconta-3(33),4,6(34 ),8(35),9,11,18(36),19,21,24,26,31-dodecaene, (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6}.1^{8,12}.1^{14,18}.0^{27,31}.0^{22,33}]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24,26,31,35-dodecaene, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aS)-, 607379-81-7, 6490-80-8, 916770-74-6

ID: 2524

chemical graph of compound 2524



InChIKey: WVWZHFJGVDNBDA-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CN2C=CNC2=S)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1349
synonyms found at PubChem are:
1-(4-Hydroxybenzyl)imidazole-2-thiol, 95333-64-5, CHEMBL164747, 4-[(2-sulfanyl-1H-imidazol-1-yl)methyl]phenol, 1-Hbit, AC1MHZIJ, NCGC00015512-01, Lopac-H-6892, Lopac0_000585, SCHEMBL1320600, SCHEMBL10621224, CTK5H7651, DTXSID20241812, MolPort-019-906-208, HMS3261F12, ZINC2568051, Tox21_500585, BDBM50014968, AKOS026729547, 1-(4-hydroxybenzyl)imidazole-2-thione, CCG-204674, LP00585, NCGC00015512-02, NCGC00015512-03, NCGC00015512-04, NCGC00093964-01, NCGC00093964-02, NCGC00261270-01, SC-21669, 1-(4-Hydroxybenzyl)-1H-imidazole-2-thiol, 4-(2-Mercapto-imidazol-1-ylmethyl)-phenol, KB-214859, EU-0100585, H 6892, 1-(4-hydroxybenzyl)-1H-imidazole-2(3H)-thione, SR-01000075914, 3-[(4-hydroxyphenyl)methyl]-1H-imidazole-2-thione, SR-01000075914-1, 1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thione, 1-(p-hydroxybenzyl)-1,3-dihydro-2H-imidazole-2-thione, Z2644278404

ID: 2525

chemical graph of compound 2525



InChIKey: WWJHRSCUAQPFQO-UHFFFAOYSA-M
SMILES: C[N+]1(CCC(CC1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3)C.[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3014059
synonyms found at PubChem are:
4-DAMP, 4-Damp methiodide, 1952-15-4, 4-Diphenylacetoxy-N-methylpiperidine methiodide, 4-DAMP iodide, 1,1-dimethyl-4-diphenylacetoxypiperidinium iodide, 4-((Diphenylacetyl)oxy)-1,1-dimethylpiperidinium iodide, CHEBI:73340, Piperidinium, 4-((diphenylacetyl)oxy)-1,1-dimethyl-, iodide, 4-(2,2-diphenylacetoxy)-1,1-dimethylpiperidinium iodide, 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-piperidinium iodide, CHEMBL76897, SR-01000075326, C21H26NO2.I, 4-DAMP methyliodide, AC1MHZ3P, 4-diphenylacetoxy-1,1-dimethylpiperidinium iodide, MLS000859984, SCHEMBL3987354, MolPort-003-940-940, REGID_for_CID_3014059, HMS2234J07, HMS3261A16, HMS3266E10, HMS3369K06, 81405-11-0 (Parent), Tox21_500407, BN0026, MFCD00078564, AKOS024458363, 4-DAMP, >=98% (HPLC), CCG-221711, CCG-222526, LP00407, NCGC00093833-01, NCGC00261092-01, SMR000326843, LS-173781, B6317, D-104, EU-0100407, FT-0742369, 1,1-dimethyl-4-diphenylacetoxypiperidiniumiodide, C-56134, J-012645, N,N-dimethyl-4-(diphenylacetoxy)piperidinium iodide, SR-01000075326-1, SR-01000075326-3, 4-DIPHENYLACETOXY-N-METHYL-PIPERIDINE METHIODIDE, (1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate iodide, 4-[(2,2-diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium iodide

ID: 2526

chemical graph of compound 2526



InChIKey: WWJZWCUNLNYYAU-UHFFFAOYSA-N
SMILES: COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5392
synonyms found at PubChem are:
temephos, Temefos, 3383-96-8, ABATE, Difos, Abathion, Biothion, Difenphos, Bithion, Nimitex, Nimitox, Procida, Swebate, Nephis 1G, Diphos (pesticide), Tetrafenphos, Abaphos, Swebat, Abate 4-E, Lypor, Ecopro 1707, Caswell No. 845, American cyanamid CL-52160, Temeguard, Temefos [USAN:INN], American cyanamid AC 52,160, Experimental insecticide 52160, Temefosum [INN-Latin], UNII-ONP3ME32DL, American cyanamid E.I. 52,160, ENT 27,165, Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester, CCRIS 8942, HSDB 956, AC 52160, CL 52160, EI 52160, OMS 786, O,O'-(Thiodi-p-phenylene) O,O,O',O'-tetramethyl bis(phosphorothioate), EINECS 222-191-1, ONP3ME32DL, EPA Pesticide Chemical Code 059001, BRN 1896901, Temephos [ANSI:BSI:ISO], AI3-27165, CHEBI:38954, O,O'-(Thiodi-4,1-phenylene)bis(O,O-dimethyl phosphorothioate), O,O,O',O'-Tetramethyl O,O'-thiodi-p-phenylene diphosphorothioate, O,O-Dimethyl phosphorothioate O,O-diester with 4,4'-thiodiphenol, WWJZWCUNLNYYAU-UHFFFAOYSA-N, O,O,O',O'-Tetramethyl O,O'-thiodi-P-phenylene bis(phosphorothioate), Phenol, 4,4'-thiodi-, O,O-diester with O,O-dimethyl phosphorothioate, O,O'-(Thiodi-4,1-phenylene)phosphorothioic acid O,O,O',O'-tetramethyl ester, Phosphorothioic acid, O,O'-(thiodi-p-phenylene) O,O,O',O'-tetramethyl ester, Bis-p-(O,O-dimethyl O-phenylphosphorothioate)sulfide, Tetramethyl O,O'-thiodi-p-phenylene phosphorothioate, NCGC00163910-02, O,O'-(Thiodi-p-phenylene) O,O,O',O'-tetramethyl di(phosphorothioate), O,O'-(Thiodi-4,1-phenylene) O,O,O',O'-tetramethyl di(phosphorothioate), Phosphorothioic acid, O,O-dimethyl ester, O,O-diester with 4,4'-thiodiphenol, DSSTox_CID_12484, DSSTox_RID_78954, Phosphorothioic acid, Op,Op'-(thiodi-4,1-phenylene) Op,Op,Op',Op'-tetramethyl ester, DSSTox_GSID_32484, Temefosum, O,O,O',O'-tetramethyl O,O'-(sulfanediyldibenzene-4,1-diyl) bis(phosphorothioate), O,O,O',O'-tetramethyl O,O'-(sulfanediyldibenzene-4,1-diyl) bis(thiophosphate), CAS-3383-96-8, Biothon, Temophos, Abat, Abate&reg;, C16H20O6P2S3, [4-(4-dimethoxyphosphinothioyloxyphenyl)sulfanylphenoxy]-dimethoxy-sulfanylidene-?^{5}-phosphane, Temefos (USAN/INN), SpecPlus_000546, Spectrum2_001873, Spectrum3_000853, Spectrum4_000693, SCHEMBL44105, BSPBio_002465, KBioGR_001185, Temephos, analytical standard, MLS002207187, DivK1c_006642, Abate(R), analytical standard, SPBio_001746, AC1L1K95, CHEMBL1355821, DTXSID1032484, KBio1_001586, KBio3_001965, dimethoxy-sulfanylidene-phosphorane, Experimental Insecticide 52,160, MolPort-003-665-457, HMS2091E03, Pharmakon1600-00330062, HY-B1120, Tox21_112075, Tox21_301778, CCG-39411, NSC755842, Temephos 10 microg/mL in Cyclohexane, AKOS026749997, Tox21_112075_1, ACM3383968, CS-4719, DB12231, NSC-755842, Phosphorothioic acid, O,O'-(thiodi-p-phenylene) O,O,O',O'-tetramethyl ester (8CI), NCGC00163910-01, NCGC00163910-03, NCGC00163910-05, NCGC00255338-01, CJ-31649, O510, SMR001253941, SBI-0052547.P003, LS-108790, FT-0603637, Temephos, PESTANAL(R), analytical standard, C18809, D06062, AB00053055_04, 383T968, C-22658, SR-05000001982, J-019338, SR-05000001982-1, Tetramethyl-O,O'-thiodi-p-phenylene phosphorothioate, [4-(4-dimethoxyphosphinothioyloxyphenyl)sulfanylphenoxy]-, O,O'-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate), O,O,O',O'-Tetramethyl O,O'-(Thiodi-p-phenylene) phosphorothioate, O,O,O',O'-tetramethyl O,O'-(thiodi-4,1-phenylene) bis(thiophosphate), O,O,O',O'-Tetramethyl O,O'-(thiodi-4,1-phenylene) phosphorothioate, O,O,O',O'-tetramethyl O,O'-4,4'-thiobis(4,1-phenylene) diphosphorothioate, [4-(4-dimethoxyphosphinothioyloxyphenyl)sulfanylphenoxy]-dimethoxy-sulfanylidene-, O,O,O',O'-tetramethyl O,O'-(sulfanediyldi-4,1-phenylene) bis(phosphorothioate), Phosphorothioic acid O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester, 53320-58-4, O-[4-((4-[(Dimethoxyphosphorothioyl)oxy]phenyl)sulfanyl)phenyl] O,O-dimethyl thiophosphate #, Pesticide1_Temephos_C16H20O6P2S3_O,O,O',O'-Tetramethyl O,O'-(sulfanediyldi-4,1-phenylene) bis(phosphorothioate)

ID: 2527

chemical graph of compound 2527



InChIKey: WWNNZCOKKKDOPX-UHFFFAOYSA-N
SMILES: C[N+]1=CC=CC(=C1)C(=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5570
synonyms found at PubChem are:
Trigonelline, 535-83-1, Caffearine, Gynesine, N-Methylnicotinate, Coffearine, Trigenolline, Trigonellin, Coffearin, Betain nicotinate, Betaine nicotinate, 1-methylpyridinium-3-carboxylate, Nicotinic acid N-methylbetaine, 1-Methylpyridinio-3-carboxylate, 1-Methyl-3-pyridiniumcarboxylate, N-Methylnicotinic acid, Trigenelline, Caffearin, 3-Carboxy-1-methylpyridinium hydroxide inner salt, N-methyl-nicotinate, N'-Methylnicotinate, UNII-3NQ9N60I00, CCRIS 1332, EINECS 208-620-5, 1-methylpyridin-1-ium-3-carboxylate, BRN 3905114, CHEBI:18123, 3NQ9N60I00, 3-Carboxy-1-methylpyridinium hydroxide, inner salt, AP-163/40806827, W-105723, Pyridinium, 3-carboxy-1-methyl-, hydroxide, inner salt, 1-methylpyridine-3-carboxylic acid, 1-methylpyridin-1-ium-3-carboxylic acid, HSDB 7684, 1-methylnicotinate, Trigonelline,(S), Pyridinium, 3-carboxy-1-methyl-, hydroxide, inner salt (8CI), N'-Methylnicotinic acid, 6138-40-5, AC1L1KN5, 5-22-02-00143 (Beilstein Handbook Reference), MLS002153895, N-Methylnicotinic acid betaine, SCHEMBL195666, SPECTRUM1500880, CHEMBL350675, 6138-41-6 (chloride), Nicotinic acid N- methylbetaine, DTXSID2026230, 60388-20-7 (tosylate), MolPort-002-495-927, WWNNZCOKKKDOPX-UHFFFAOYSA-N, HMS2096H08, HMS2234K22, HMS3371K21, CCG-38517, FCH920428, NSC714350, SBB085963, AKOS005067859, LS-1330, NSC-714350, SDCCGMLS-0066739.P001, NCGC00095649-01, NCGC00095649-02, NCGC00095649-03, NCGC00095649-04, AN-45679, AS-17722, SMR001233244, ZB000241, AB0020602, KB-160113, 1-Methyl-Nicotinic Acid Anion(Trigonelline), AB00052974, FT-0689338, N2788, Pyridinium,3-carboxy-1-methyl-, inner salt, V1545, Pyridinium, 3-carboxy-1-methyl-, inner salt, C01004, 3-carboxy-1-methyl-Pyridinium hydroxide inner salt

ID: 2528

chemical graph of compound 2528



InChIKey: WWXBHTZSYYGCSG-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1NC(=O)N)[As](=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8480
synonyms found at PubChem are:
Carbarsone, Amebarsene, Amebarsone, Aminarson, Arsambide, Carbarson, Fenarsone, Leucarsone, Pentarsone, Ameban, p-Ureidobenzenearsonic acid, Amibiarson, Aminarsone, Aminoarson, Amabevan, Histocarb, Kutan, 121-59-5, p-Arsonophenylurea, 4-Ureidophenylarsonic acid, Carb-O-Sep, N-Carbamoylarsanilic acid, Aminarsonum, Phenarsone, p-Carbamidobenzenearsonic acid, N-Carbamyl arsanilic acid, Histocarb (VAN), 4-Carbamylaminophenylarsonic acid, p-Carbamidophenylarsonic acid, 4-Ureido-1-phenylarsonic acid, Benzenearsonic acid, p-ureido-, 4-Ureidobenzolarsonsaeure, Carbarson [INN-Spanish], Carbarsonum [INN-Latin], C7H9AsN2O4, UNII-8PK70TXE1T, NSC 32868, Arsanilic acid, N-carbamoyl-, Carbaminophenyl-p-arsonic acid, p-Carbamino phenyl arsonic acid, EINECS 204-484-6, Kyselina N-karbamylarsanilova [Czech], 4-Ureidobenzenearsonic acid, [4-(carbamoylamino)phenyl]arsonic acid, BRN 2940926, 8PK70TXE1T, AI3-17288, (4-((Aminocarbonyl)amino)phenyl)arsonic acid, Arsonic acid, [4-[(aminocarbonyl)amino]phenyl]-, [4-[(AMINOCARBONYL)AMINO]PHENYL]ARSONIC ACID, NCGC00016374-02, CAS-121-59-5, DSSTox_CID_246, {4-[(aminocarbonyl)amino]phenyl}arsonic acid, DSSTox_RID_75460, Arsonic acid, (4-((aminocarbonyl)amino)phenyl)-, DSSTox_GSID_20246, Carbarsonum, Carbarsone [INN], Carbarsone [USP:INN], Kyselina N-karbamylarsanilova, Carbasone, Histocarb-sol., Histocarb-Soluble, Prestwick0_000413, Prestwick1_000413, Prestwick2_000413, Prestwick3_000413, AC1Q4ZV8, WLN: ZVMR D-AS-QQO, (4-ureidophenyl)arsonic acid, BSPBio_000366, 3-16-00-01112 (Beilstein Handbook Reference), MLS000728528, Carbamidophenyl-p-arsonic acid, SCHEMBL300590, SPBio_002305, AC1L1R34, BPBio1_000404, CHEMBL1331366, DTXSID4020246, CHEBI:94806, HMS1569C08, HMS2096C08, HMS2225A09, HMS3346K01, HMS3713C08, Pharmakon1600-01503868, NSC32868, Tox21_110404, Tox21_201049, 7882AF, LS-651, NSC-32868, NSC759884, Tox21_110404_1, CCG-213223, NSC-759884, NCGC00016374-01, NCGC00016374-03, NCGC00016374-05, NCGC00091889-01, NCGC00258602-01, NCI60_002860, SMR000445643, AB00513834, FT-0631695, AB00513834_08, C-16198, SR-01000777573, SR-01000777573-2

ID: 2529

chemical graph of compound 2529



InChIKey: WWXYYTOHUGNKSA-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O.C(C(C(=O)O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 16667700
synonyms found at PubChem are:
Carvedilol tartrate, NCGC00095120-01, DSSTox_CID_25916, DSSTox_RID_81223, DSSTox_GSID_45916, CAS-NOCAS_45916, BSPBio_002823, SCHEMBL973795, SPECTRUM1504257, CHEMBL1437006, DTXSID5045916, NOCAS_45916, HMS1922H21, Tox21_111431, CCG-39083, Tox21_111431_1, NCGC00095120-02, NCGC00167832-06

ID: 2530

chemical graph of compound 2530



InChIKey: WWYMZGJMIXWAPQ-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C=C1)OC)NC2=NC3=CC=CC=C3C(=C2)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "N Pedemonte" "GL Lukacs" "LJ Galietta" "O Zegarra-Moran" "AS Verkman" "K Du"


CID is 619056
synonyms found at PubChem are:
N-(2-methoxy-5-methylphenyl)-4-methylquinolin-2-amine, AC1LDIDG, CBMicro_015601, Oprea1_744257, SCHEMBL838120, ZINC84816, MolPort-000-807-871, WWYMZGJMIXWAPQ-UHFFFAOYSA-N, STK378457, AKOS001744412, MCULE-5379874838, BIM-0015389.P001, ST4054371, SR-01000529067, SR-01000529067-1, (2-methoxy-5-methylphenyl)(4-methyl(2-quinolyl))amine, A2226/0093758, N-(2-Methoxy-5-methylphenyl)-4-methyl-2-quinolinamine #, N-(2-methoxy-5-methylphenyl)-N-(4-methyl-2-quinolyl)amine, Quinolin-2-amine, 4-methyl-N-(2-methoxy-5-methylphenylamino)-

ID: 2531

chemical graph of compound 2531



InChIKey: WWYNJERNGUHSAO-XUDSTZEESA-N
SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 13109
synonyms found at PubChem are:
Levonorgestrel, norgestrel, 797-63-7, D-Norgestrel, (-)-Norgestrel, Levonova, Microval, Postinor, Mirena, Jadelle, Neogest, Ovrette, Plan B, NORPLANT, Norplant 2, Follistrel, Microlution, Microgyn, Microlut, Monovar, Ovranette, Triagynon, Triciclor, Trivora, Nordet, Trigoa, 18-Methylnorethisterone, Levonorgestrelum, Microgynon CD, Microgest ED, Norplant II, Logynon ED, Ovral-Lo, Levlen ED, Microgynon 21, Microgynon 28, Trinordiol 21, Trinordiol 28, d(-)-Norgestrel, Minivlar 30, Monofeme 28, Neogynon 21, Nordette 21, Nordette 28, Stediril 30, Levonelle, Trifeme 28, Levlen, Preven, Microgynon 30 ED, Tri-Levlen 21, Levora-21, Levora-28, Rigevidon 21+7, NorLevo, Triquilar ED, LO/Ovral, Triphasil 21, Triphasil 28, LD norgestrel [French], Levonorgestrelum [INN-Latin], Norgestrelum, Norgestrelum [INN-Latin], Capronor, D-(-)-Norgestrel, Nordette, Norgeston, Levonorgestrel implants, E-Gen-C, alpha-Norgestrel, Tri-Levlen, Norgestrel [Progestins], Norplant-2, Ovoplex 30-150, 6533-00-2, Methylnorethindrone, Norgestrel-(-)-D, Wy 3707, Wy-5104, Ld norgestrel, Microluton, Tetragynon, UNII-5W7SIA7YZW, 17-Ethynyl-18-methyl-19-nortestosterone, Postinor-2, Wy-3707, FH 122-A, 17alpha-Ethynyl-18-homo-19-nortestosterone, Norplant System in Plastic Container, SH 850, Norplant (TN), Ovrette (TN), 18-Methyl-17-alpha-ethynyl-19-nortestosterone, dl-Norgestrel, Mirena (TN), CCRIS 6525, CCRIS 9033, component of Lo/ovral, SH 70850, HSDB 3595, HSDB 6483, Levonorgestrel [USAN:INN:BAN], 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one, 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one, 17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol, Norgestrel [USAN:BAN:INN:JAN], Norgestrel [USAN:INN:BAN:JAN], 17alpha-Ethynyl-13-ethyl-19-nortestosterone, 13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one, 13beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one, EINECS 212-349-8, EINECS 229-433-5, 5W7SIA7YZW, 72-HOURS, BRN 2391114, 13-Ethyl-17alpha-ethynylgon-4-en-17beta-ol-3-one, 18,19-Dinor-4-pregnen-20-yn-3-one, dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone, DNorgestrel, MLS000069491, CHEBI:6443, (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, Levonorgestrel (JAN/USP/INN), 19-Nortestosterone, 17-ethynyl-18-methyl-, 17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one, SOH-075, 13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one, (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one, 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-(+-)-, 13-Ehyl-17alpha-ethynyl-17-hydroxygon-4-en-3-one, MFCD00199013, NCGC00159349-02, SMR000059117, dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one, 17-beta-Hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one, 17alpha-Ethynyl-18-homo-19-nor-testosterone, (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one, 17-alpha-Ethynyl-13-ethyl-19-nortestosterone, 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-(-)-, DSSTox_CID_16496, DSSTox_RID_79283, DSSTox_GSID_36496, (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, Norgestrel (JP15/USP/INN), 17alpha-ethynyl-17beta-hydroxy-18a-homoestr-4-en-3-one, 13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one, Levogel, Levosert, Liletta, Skyla, 13-ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, Next choice, Fallback Solo, 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE, 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-, Plan B One Step, Plan B One-Step, Levonorgestrel (Levonelle), LNG-IUS, Levonelle, D-Norgestrel, Levonova, Levonorgestrel, Kyleena, 1lhv, Oral levonorgestrel, CAS-797-63-7, Prestwick_109, (+-)-Norgestrel, (-)-Levonorgestrel, Levonorgestrel [USAN:USP:INN:BAN], Levonorgestrel implant, Skyla (TN), BAY86-5028, Norgestrel [USAN:USP:INN:BAN:JAN], BAY 86-5028, 18-Methylnorethindrone, Opera_ID_552, AC1Q6OEV, Levonorgestrel(Levonelle), Prestwick0_000773, Prestwick1_000773, Prestwick2_000773, Prestwick3_000773, Intrauterine levonorgestrel, D0A9MR, D0BA9U, D0G6CT, (-)-Norgestrel, 98%, CHEMBL1389, BIDD:PXR0194, SCHEMBL27597, BSPBio_000846, MLS000759484, MLS001074069, MLS001423967, SPBio_002785, 13-Ethyl-17alpha-ethynyl-17-hydroxygon-4-en-3-one, AC1L211U, BPBio1_000932, GTPL2881, Levonelle;D-Norgestrel;Levonova, Norgestrel (JP17/USP/INN), DTXSID3036496, MolPort-002-510-453, WWYNJERNGUHSAO-XUDSTZEESA-N, HMS1570K08, HMS2051M08, HMS2090O06, HMS2097K08, HMS2232H06, HMS2232K12, HMS3649J10, HMS3714K08, (1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, BCP21999, HY-B0257, ZINC3814395, D-(-)-Norgestrel (Levonorgestrel), Tox21_111593, Tox21_202872, Tox21_303658, BDBM50410522, LMST02030119, NSC744007, s1727, D(-)-Norgestrel, analytical standard, AKOS015894913, Tox21_111593_1, BCP9000852, CCG-100853, CS-2243, DB00367, MCULE-1283162506, NC00103, NSC-744007, [18,(17.alpha.)-(-)-], NCGC00159349-03, NCGC00159349-05, NCGC00257283-01, NCGC00260418-01, AJ-45701, LS-62083, LS-62084, SMR000653526, AB0012485, AB2000252, FT-0658692, N0889, C08149, C08153, D00950, D00954, EN300-122613, 797L637, A835065, SR-01000759218, SR-01000946725, (-)-17alpha-Ethynyl-18-methyl-19-nortestosterone, SR-01000759218-5, SR-01000946725-1, BRD-K35189033-001-03-0, 13-ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one, Z1551429747, 13beta-ethyl-17alpha-ethynyl-17-hydroxy-gon-4-en-3-one, UNII-3J8Q1747Z2 component WWYNJERNGUHSAO-XUDSTZEESA-N, (17?)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-yn-3-one, 13beta-Ethyl-17alpha-ethynyl-17 beta-hydroxygon-4-en-3-one, 13beta-ethyl-17alpha-ethynyl-17beta-hydroxy-gon-4-en-3-one, Levonorgestrel, European Pharmacopoeia (EP) Reference Standard, 18,19-Dinor-13beta-ethyl-17 beta hydroxy-4-pregnen-20-yn-3-one, 18,19-Dinor-13beta-ethyl-17beta-hydroxy-4-pregnen-20-yn-3-one, Levonorgestrel, United States Pharmacopeia (USP) Reference Standard, (-)-18,19-Dinor-13beta-ethyl-17beta-hydroxy-4-pregnen-20-yn-3-one, [(-)-13-ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one, [18,19-Dinorpregn-4-en-20-yn-3-one-13-ethyl-17-hydroxy-,(17..)-(-)-], 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+)-, Levonorgestrel for system suitability 2, European Pharmacopoeia (EP) Reference Standard, Levonorgestrel, Pharmaceutical Secondary Standard; Certified Reference Material, (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one, (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-oxidanyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, 121714-72-5, 4222-79-1, 797-62-6

ID: 2532

chemical graph of compound 2532



InChIKey: WXAYTPABEADAAB-UHFFFAOYSA-N
SMILES: CN1CCCN=C1COC(=O)C(C2CCCCC2)(C3=CC=CC=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 66061
synonyms found at PubChem are:
Oxyphencyclimine hydrochloride, Daricon, 125-52-0, Ulcociclinina, Spazamin, Syklifen, Cycmin, Dominil, Enterex, Gastrix, Oximin, Setrol, Vio-Thene, W-T Anticholinergic, Manir, Vagogastrin, Oxyphencyclimine HCl, Vistrax, Oxyphencyclimine (hydrochloride), EINECS 204-742-8, NSC 528449, S 1-1236, MLS000069551, Oxyphencyclimine hydrochloride [JAN], 21609-10-9, NCGC00095084-01, SMR000058818, 1-Methyl-1,4,5,6-tetrahydro-2-pyrimidylmethyl-alpha-cyclohexyl-phenylglycolate hydrochloride, DSSTox_CID_25909, DSSTox_RID_81220, DSSTox_GSID_45909, (1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)methyl alpha-phenylcyclohexaneglycolate monohydrochloride, (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride, Oxyphencyclimine hydrochloride (JAN), Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester monohydrochloride, CAS-125-52-0, Cyclohexaneglycolic acid, alpha-phenyl-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride, (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate;hydrochloride, component of Enarax, Daricon (TN), component of Vistrax, Oxyphencyclimine hydrochloride [USP:JAN], Oxiphencyclimine Chloride, Opera_ID_1394, AC1L24JB, MLS001074201, SCHEMBL663333, SPECTRUM1503932, REGID_for_CID_66061, CHEBI:7869, 125-53-1 (Parent), CHEMBL1200891, DTXSID6045909, CTK8G2233, HMS1922M10, Pharmakon1600-01503932, BCP19587, HY-B0954, Tox21_111416, CCG-39378, NSC528449, NSC758648, AKOS030526360, Tox21_111416_1, NSC-528449, NSC-758648, NCGC00018210-05, NCGC00095084-02, NCGC00095084-03, oxyphencyclimine preparation hydrochloride, LS-56872, KB-205231, FT-0707726, D01006, Q-201529, Benzeneacetic acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride, BENZENEACETIC ACID, A-CYCLOHEXYL-A-HYDROXY-,(1,4,5,6-TETRAHYDRO-1-METHYL-2-PYRIMIDINYL)METHYL ESTER, HYDROCHLORIDE (1:1), Benzeneacetic acid,a-cyclohexyl-a-hydroxy-,(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester,hydrochloride(1:1), Cyclohexaneglycolic acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester monohydrochloride, Cyclohexaneglycolic acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride, AC1LCW99, SCHEMBL14672528, hydron; (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate; chloride

ID: 2533

chemical graph of compound 2533



InChIKey: WXNZTHHGJRFXKQ-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4684
synonyms found at PubChem are:
4-CHLOROPHENOL, p-Chlorophenol, 106-48-9, parachlorophenol, Phenol, 4-chloro-, 4-Hydroxychlorobenzene, Phenol, p-chloro-, Applied 3-78, 4-Monochlorophenol, p-Chlorophenic acid, p-Chlorfenol, 4-Chloro-1-hydroxybenzene, p-Chlorfenol [Czech], 4-Chlorphenol, Parachlorophenol [USP], 4-chloro-phenol, NSC 2877, UNII-3DLC36A01X, CCRIS 642, HSDB 1414, C6H5ClO, EINECS 203-402-6, Parachlorophenol (JAN/USP), AI3-19422, 3DLC36A01X, CHEBI:28078, WXNZTHHGJRFXKQ-UHFFFAOYSA-N, NCGC00090814-01, DSSTox_CID_1871, DSSTox_RID_76376, DSSTox_GSID_21871, p-Chlorophenol, liquid [UN2021] [Keep away from food], p-Chlorophenol, solid [UN2020] [Keep away from food], CAS-106-48-9, 4chlorophenol, p-chloro phenol, para-chlorophenol, parachloro phenol, 4-chloro phenol, 4CH, Parachlorophenol,(S), p-Chlorophenol, solid, p-Chlorophenol, liquid, PubChem22009, Spectrum_000939, AC1L1IPY, AC1Q7AEN, Spectrum2_000968, Spectrum3_000539, Spectrum4_000468, Spectrum5_001228, PARA CHLORO PHENOL, CHLOROPHENOL(4-), WLN: QR DG, 1-Chloro-4-hydroxybenzene, 4-ClC6H4OH, ACMC-2098jw, bmse000461, EC 203-402-6, AC1Q78UH, 4-Chlorophenol, >=99%, SCHEMBL28864, BSPBio_002157, KBioGR_000916, KBioSS_001419, KSC174K7J, MLS002454432, BIDD:ER0011, CHEMBL57053, DivK1c_000310, SPECTRUM1500460, SPBio_000975, PARAGOS 390356, ZINC1885, 4-Chlorophenol, 99% 50g, DTXSID1021871, BDBM36299, CTK0H4574, HMS500P12, KBio1_000310, KBio2_001419, KBio2_003987, KBio2_006555, KBio3_001657, KS-00000VEZ, RARECHEM FH 2C 0018, TIMTEC-BB SBB040864, NSC2877, MolPort-000-872-025, NINDS_000310, OTAVA-BB 1506172, 1121-74-0 (potassium salt), HMS1920F08, HMS2091N08, HMS2230B13, HMS3373O02, LABOTEST-BB LTBB002362, Pharmakon1600-01500460, 1-CHLORO-4-HYDROXY-BENZENE, NSC-2877, 1193-00-6 (hydrochloride salt), AKOS BBS-00004332, Tox21_111028, Tox21_201704, Tox21_302860, ANW-15354, CCG-40184, LS-401, MFCD00002318, NSC757263, SBB040864, STL194293, 4-Chlorophenol, for synthesis, 98%, AKOS000118967, Tox21_111028_1, AS00215, DB13154, MCULE-4022476067, MP-2149, NSC-757263, RP19818, RTR-013097, TRA0010400, IDI1_000310, NCGC00090814-02, NCGC00090814-03, NCGC00090814-04, NCGC00090814-05, NCGC00090814-07, NCGC00256497-01, NCGC00259253-01, 4-Chlorophenol 10 microg/mL in Methanol, AJ-08107, AN-22436, CJ-00069, KB-09010, SC-19124, SMR001252242, ZB000430, 4-Chlorophenol 100 microg/mL in Methanol, SBI-0051474.P003, AB1003203, DB-028832, KB-241041, ST2411367, TL8000232, 4-Chlorophenol, puriss., >=99.0% (GC), CS-0005709, FT-0618238, ST50214454, C02124, D00149, 93919-EP2269977A2, 93919-EP2272509A1, 93919-EP2277858A1, 93919-EP2284157A1, 93919-EP2298743A1, 93919-EP2298747A1, 93919-EP2298750A1, 93919-EP2305625A1, AB00052066_06, 148113-EP2269977A2, 148113-EP2280005A1, 148113-EP2289884A1, 4-Chlorophenol, PESTANAL(R), analytical standard, SR-05000001691, J-001599, SR-05000001691-1, BRD-K40992116-001-05-5, F0001-0124, p-Chlorophenol, liquid [UN2021] [Keep away from food], p-Chlorophenol, solid [UN2020] [Keep away from food], Z1262246118, UNII-AZ1041M258 component WXNZTHHGJRFXKQ-UHFFFAOYSA-N, UNII-E9JIO40PSX component WXNZTHHGJRFXKQ-UHFFFAOYSA-N, 1-(4-CHLOROPHENOXY)-1-CHLORO-3,3-DIMETHYL-2-BUTANONE, InChI=1/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8, Parachlorophenol, United States Pharmacopeia (USP) Reference Standard, 4-Chlorophenol solution, 725 mg/L in H2O, for AOX determination (according to DIN 38409-H14)

ID: 2534

chemical graph of compound 2534



InChIKey: WXTMDXOMEHJXQO-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1O)C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3469
synonyms found at PubChem are:
2,5-DIHYDROXYBENZOIC ACID, gentisic acid, 490-79-9, Hydroquinonecarboxylic acid, Gentisate, Benzoic acid, 2,5-dihydroxy-, 5-Hydroxysalicylic acid, Gensigen, Gensigon, 2,5-Dioxybenzoic acid, 2,5-Dhba, Gentisinic acid, Salicylic acid, 5-hydroxy-, Carboxyhydroquinone, Kyselina gentisinova, Gentisinate, UNII-VP36V95O3T, NSC 27224, Kyselina gentisinova [Czech], Acide gentisique [INN-French], Acido gentisico [INN-Spanish], Acidum gentisicum [INN-Latin], Kyselina 2,5-dihydroxybenzoova, EINECS 207-718-5, Acido 2,5-diidrossibenzoico [Italian], 2,5-Dihydroxy benzoic acid, BRN 2209119, Kyselina 2,5-dihydroxybenzoova [Czech], CHEMBL1461, AI3-60431, VP36V95O3T, CHEBI:17189, 3,6-dihydroxybenzoic acid, WXTMDXOMEHJXQO-UHFFFAOYSA-N, BENZOIC ACID,2,5-DIHYDROXY, Gentinatre, Gentalpin, Gentasol, Gentidol, Gentisan, Gentisod, Legential, Nagentis, Casate, Gabail, Nagent, Casate sodium, Gensalate sodium, Sodium-Gent, WLN: QVR BQ EQ, GENTISATE SODIUM, Acido gentisico, Acide gentisique, Acidum gentisicum, NSC8512, Gentisic acid [INN], Acido 2,5-diidrossibenzoico, Dihydroxybenzoicacid, GTQ, 2,5-Dioxybenzoate, GENOP, 2-Carboxyhydroquinone, 5-hydroxy-Salicylate, Mesalamine Impurity G, 3,6-Dihydroxybenzoate, Gentisinic acid polymer, PubChem14414, Spectrum_001241, 2,5dihydroxybenzoic acid, 5-hydroxy-Salicylic acid, Spectrum2_000773, Spectrum3_001326, Spectrum4_001821, Spectrum5_000581, 2,5-DihydroxybenzoicAcid, ACMC-1AP4E, 2,5,dihydroxybenzoic acid, bmse000326, AC1Q72IE, SCHEMBL3690, 2,5-dihydroxy-benzoic acid, 2,5-Dihydroxybenzoate, VI, 2-Carboxybenzene-1,4-diol, NCIOpen2_000913, Oprea1_039290, BSPBio_003051, KBioGR_002487, KBioSS_001721, 4-10-00-01441 (Beilstein Handbook Reference), KSC236E9L, MLS002207134, Benzoicacid, 2,5-dihydroxy-, DivK1c_000538, SPBio_000846, AC1L1G08, ZINC1507, DTXSID4060078, CTK1D6295, HMS501K20, KBio1_000538, KBio2_001721, KBio2_004289, KBio2_006857, KBio3_002271, KS-00000COX, Sodium Gentisate (gentisic acid), MolPort-001-508-497, NINDS_000538, 2,5-Dihydroxybenzoic acid, 98%, NSC27224, NSC49098, ANW-30725, BBL013232, BDBM50335808, CCG-40154, MFCD00002460, NSC-27224, NSC-49098, SBB058777, STK426343, AKOS003267857, AS04641, CS-W001179, HY-W001179, MCULE-7171470745, PS-6232, RP21805, RTC-063574, TRA0007893, VZ22769, IDI1_000538, 4955-90-2 (mono-hydrochloride salt), NCGC00178325-01, AC-23625, AJ-08040, AN-15435, AN-21385, KB-67554, LS-71157, SC-46608, SMR000393742, gentisic acid (2,5-dihydroxybenzoic acid), DB-051598, ST2415865, TC-063574, D0569, D2933, FT-0610382, ST50824443, EN300-81715, 2,5-Dihydroxybenzoic acid, analytical standard, C00628, K-9198, AE-562/40605400, Resorcyllic acid, alphaodium 2,5-dihydroxybenzoate, I01-0126, W-106033, 26A2CD0F-7EBD-431F-8BDA-168766205AE1, Z275164274, 2,5-Dihydroxybenzoic acid, matrix substance for MALDI-MS, >99.0% (HPLC), 2,5-Dihydroxybenzoic acid, matrix substance for MALDI-MS, >=99.5% (HPLC), Ultra pure, InChI=1/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11

ID: 2535

chemical graph of compound 2535



InChIKey: WXUQBKOBXREBBX-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=CC(=N2)[N-]S(=O)(=O)C3=CC=C(C=C3)N.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 71594
synonyms found at PubChem are:
SULFAQUINOXALINE SODIUM, 967-80-6, Sulfaquinoxaline sodium salt, Sulfquinoxaline sodium, UNII-21223EPJ40, N'1-Quinoxalin-2-ylsulphanilamide sodium salt, sodium (4-aminophenyl)sulfonyl-quinoxalin-2-yl-azanide, 21223EPJ40, N-(2-Quinoxalinyl)Sulfanilamide Sodium Salt, 2-p-Aminobenzenesulfonamidoquinoxaline Soidum Salt, Q-201764, Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-, monosodium salt, SR-05000001773, EINECS 213-526-2, sulfaquinoxaline sod., sodium sulfaquinoxaline, Sulphaquinoxaline Sodium, AC1MW3UL, N'1-Quinoxalin-2-ylsulphanilamide, sodium salt, C14H11N4NaO2S, MLS002153979, SPECTRUM1501145, AC1Q1W34, sulfaquinoxaline sodium cp2000, CHEMBL1527324, sodium[(4-aminophenyl)sulfonyl](quinoxalin-2-yl)azanide, HMS500B17, HY-B1282A, MolPort-003-666-366, MolPort-003-933-424, HMS1570C04, HMS2092H03, HMS2097C04, HMS2230E09, HMS3369G20, HMS3714C04, CCG-40204, SBB061721, AKOS024255725, AKOS024374990, API0004279, CS-8211, KS-5332, NCGC00017031-01, NCGC00017031-02, NCGC00017031-03, NCGC00094910-01, NCGC00094910-02, Sulfaquinoxaline sodium salt, >=92.5%, CAS-967-80-6, O350, SC-15956, SMR001233316, AB0016406, FT-0633200, ST51015122, 967S806, A832301, C-36591, SR-05000001773-1, SR-05000001773-3, 4-amino-N-(quinoxalin-2-yl)-N-sodiobenzenesulfonamide, sodium (4-aminophenyl)sulfonyl-(2-quinoxalinyl)azanide, sodium (4-aminophenyl)sulfonyl-quinoxalin-2-ylazanide, sodium (4-aminophenylsulfonyl)(quinoxalin-2-yl)amide, [(4-aminophenyl)sulfonyl]quinoxalin-2-ylamine, sodium salt, Sulfaquinoxaline sodium, Antibiotic for Culture Media Use Only

ID: 2536

chemical graph of compound 2536



InChIKey: WXURHACBFYSXBI-GQKYHHCASA-N
SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 16490
synonyms found at PubChem are:
flumethasone, 2135-17-3, Flumetasone, Aniprime, Flucorticin, Flumethason, Anaprime, Methagon, Fluvet, Flumetasona, Flumetasonum, Cortexilar, Flumethasonum, 6alpha-Fluorodexamethasone, RS 2177, Flucort (Veterinary), 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, NSC 54702, Flumetasonum [INN-Latin], UNII-LR3CD8SX89, 6-alpha-Fluorodexamethasone, Flumetasona [INN-Spanish], RS-2177, LR3CD8SX89, MLS000028618, CHEBI:34764, 6alpha,9alpha-Difluoro-16alpha-methylprednisolone, U-10974, EINECS 218-370-9, Flumetasone (INN), Flumetasone [INN], (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, Flumethasone (USAN), Flumethasone [USAN], BRN 5645455, SMR000058690, DSSTox_CID_25365, DSSTox_RID_80828, DSSTox_GSID_45365, Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6alpha,11beta,16alpha)-, Vecort, U-10,974, C22H28F2O5, Fluorodexamethasone, 6alpha,9alpha-Difluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione, 6.alpha.-Fluorodexamethasone, Cortexillar, Aniprome, NSC54702, fluorodexamethazone, NCGC00016604-01, Prestwick_229, CAS-2135-17-3, 6|A-Fluorodexamethasone, 6|A-Fluorodexamethazone, U 10974, Opera_ID_1501, Prestwick0_000734, Prestwick1_000734, Prestwick2_000734, Prestwick3_000734, Flumethasone [USAN:BAN], 6alpha-Fluoro-dexamethasone, SCHEMBL4046, BSPBio_000688, MLS001077306, SPBio_002627, BPBio1_000758, 6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, CHEMBL1201392, DTXSID2045365, MolPort-003-847-393, WXURHACBFYSXBI-GQKYHHCASA-N, HMS1570C10, HMS2097C10, HMS2234B11, HMS3714C10, (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0?,?.0??,??]heptadeca-3,6-dien-5-one, (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, AC1L2823, HY-B1051, ZINC3983936, Tox21_110518, MFCD00056464, s4088, AKOS005256462, AKOS015895435, Tox21_110518_1, AC-2069, ACN-037575, CCG-220734, CS-4573, DB00663, MCULE-2421243179, RL02628, SMP1_000127, NCGC00021761-03, NCGC00021761-05, NCGC00021761-06, AJ-47589, AN-14319, AS-12534, BC216012, CC-24142, SC-18787, 6|A,9|A-Difluoro-16|A-methylprednisolone, AB2000744, LS-118448, F0945, FT-0626440, ST24047211, C14479, D04208, EC 218-370-9, 135F173, C-21898, SR-01000003144, Q-101387, SR-01000003144-3, BRD-K61496577-001-03-8, BRD-K61496577-001-20-2, 6.alpha., 9.alpha.-Difluoro-16.alpha.-methylprednisolone, (6?,11?,16?)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 6|A,9|A-Difluoro-16|A-methyl-11|A,17|A,21-trihydroxy-1,4-pregnadiene-3,20-dione, (6|A,11|A,16|A)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 6.alpha., 9-Difluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1, 4-diene-3,20-dione, 6|A,9|A-Difluoro-16|A-methyl-11|A,17|A,21-trihydroxy-1,4-pregnadiene-3,20-dione; 6|A,9|A-Difluoro-16|A-methylprednisolone; 6|A-Fluorodexamethasone, 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Flumetasone), Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17, 21-trihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-, Pregna-1,4-diene-3,20-dione, 6-alpha,9-difluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-, Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-16alpha-methyl-(VAN), Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,17,21-trihydroxy-16alpha-methyl-(VAN) (8CI)

ID: 2537

chemical graph of compound 2537



InChIKey: WYEPBHZLDUPIOD-UHFFFAOYSA-N
SMILES: CC(=O)CC(=O)CCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5312
synonyms found at PubChem are:
4,6-DIOXOHEPTANOIC ACID, Succinylacetone, 51568-18-4, succinyl acetone, Heptanoic acid, 4,6-dioxo-, NSC 174804, CCRIS 1387, CHEMBL222824, CHEBI:87897, WYEPBHZLDUPIOD-UHFFFAOYSA-N, 4.6-dioxoheptanoic acid, 4,6-Dioxoheptanoate, 4,6-dioxoheptans, Spectrum_001999, 4,6-Dioxoheptanoicacid, SpecPlus_000704, AC1Q5GTV, Heptanoic acid,6-dioxo-, Spectrum2_000467, Spectrum3_000763, Spectrum4_001249, Spectrum4_001266, AC1L1K2N, BSPBio_002406, KBioGR_001778, KBioGR_001852, KBioSS_002574, DivK1c_006800, SCHEMBL503918, SPBio_000574, CTK8B9814, KBio1_001744, KBio2_002565, KBio2_005133, KBio2_007701, KBio3_001626, 4,6-Dioxoheptanoic acid, powder, DTXSID50199519, MolPort-003-940-967, BCP17098, 7197AB, ANW-63187, BDBM50197063, CCG-39960, MFCD00002797, NSC174804, AKOS006282601, ZINC100036983, CS-W010900, HY-W010184, NSC-174804, TRA0044142, ACM51568184, NCGC00178670-01, AN-41256, CC-17414, DA-05297, KB-35838, NCI60_001428, AX8092906, LS-175284, TC-151932, FT-0674727, 33908-EP2275420A1, 33908-EP2284148A1, 33908-EP2289882A1, 33908-EP2289886A1, 33908-EP2295055A2, 33908-EP2295416A2, 33908-EP2298748A2, 33908-EP2298764A1, 33908-EP2298765A1, 33908-EP2305627A1, 33908-EP2305642A2, 33908-EP2305661A1, 33908-EP2308855A1, 33908-EP2311453A1, 33908-EP2371797A1, 33908-EP2371798A1, 33908-EP2371800A1, 33908-EP2371802A1, 33908-EP2371804A1, 568D184, C-33623

ID: 2538

chemical graph of compound 2538



InChIKey: WYJAPUKIYAZSEM-MOPGFXCFSA-N
SMILES: CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 71203
synonyms found at PubChem are:
Vinburnine, (-)-Eburnamonine, Vincamone, eburnamonine, Eburnal, l-Eburnamonine, 4880-88-0, Eburnamonine (-), Eburnal ritardo, cis-Vincamone, Vinburnine [INN], Vincamona [Spanish], Vinburninum [INN-Latin], Vinburnina [INN-Spanish], UNII-G54D0HMY25, CH-846, (-)-Eburnamonina [Spanish], 3-alpha,16-alpha-Eburnamonine, Eburnamonine (-)-form, EINECS 225-490-5, CH 846, NSC 322920, 3alpha,16alpha-Eburnamonine, CHEBI:4740, G54D0HMY25, (3alpha,16alpha)-Eburnamenin-14(15H)-one, (3-alpha,16-alpha)-Eburnamin-14(15H)-one, Vinburnine (INN), NSC322920, (+/-)-Eburnamonine, DSSTox_CID_25119, DSSTox_RID_80685, DSSTox_GSID_45119, Vinburnina, Vinburninum, Vincanorine, Vincamona, DL-Eburnamonine, 16-Oxoeburnane, (-)-Eburnamonina, (+/-)-Vincamone, MLS000758467, Vinburnine, (+/-)-, Vinburnine base, Vinburnine/, NSC-322920, Eburnamonine (+/-)-form [MI], NCGC00014750-02, Cervoxan (TN), 2580-88-3, (-)-Vincamone, Prestwick_189, CAS-4880-88-0, eburnamonine, (3alpha,16alpha)-isomer, (-)-cis-Eburnamonine, Eburnamenin-14(15H)-one, (+/-)-, Spectrum_000379, AC1L2FQG, Prestwick0_000607, Prestwick1_000607, Prestwick2_000607, Prestwick3_000607, Spectrum2_001504, Spectrum3_001199, Spectrum4_000751, Spectrum5_000938, D0S4DT, AC1Q6PB6, NCIStruc1_000941, NCIStruc2_000870, Eburnamin-14(15H)-one, (3-alpha,16-alpha)-, BSPBio_000514, BSPBio_002877, GTPL345, KBioGR_001102, KBioSS_000859, MLS002153906, DivK1c_000411, SCHEMBL456385, SPBio_001547, SPBio_002733, BPBio1_000566, MEGxp0_001871, CHEMBL1892145, DTXSID6045119, ACon1_000004, HMS501E13, KBio1_000411, KBio2_000859, KBio2_003427, KBio2_005995, KBio3_002377, AOB5555, MolPort-001-742-589, NINDS_000411, HMS1569J16, HMS2096J16, HMS2233K13, HMS3713J16, ACT03251, BCP02373, HY-B1180, Tox21_110060, ABP000719, CCG-36740, NCI322920, ZINC19796061, AKOS015896486, Tox21_110060_1, CS-4789, MCULE-1030644698, MCULE-3457597200, IDI1_000411, NCGC00262533-02, NCGC00262533-03, AC-26459, CC-00046, NCI60_002800, SMR001233255, (3?,16?)-Eburnamenin-14(15H)-one, SBI-0051740.P002, LS-162178, ST24026040, W6490, C09149, D08676, C-18463, I06-1884, BRD-K40227168-001-03-8, BRD-K40227168-001-06-1, Eburnamin-14(15H)-one, (3-alpha,16-alpha)- (9CI), UNII-64UB2942IE component WYJAPUKIYAZSEM-MOPGFXCFSA-N, NCGC00262533-03_C19H22N2O_(3alpha,16alpha)-14,15-Dihydroeburnamenin-14-one, (31S,6aS)-6a-ethyl-31,4,5,6,6a,7-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-8(2H)-one, 13090-13-6, 412037-03-7, 6880-38-2

ID: 2539

chemical graph of compound 2539



InChIKey: WYRXIEUFRVSVEM-UHFFFAOYSA-N
SMILES: CCOC(=O)C1C(=NN(C1=O)C2=CC=CC=C2)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 608210
synonyms found at PubChem are:
29711-06-6, Ethyl 3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-carboxylate, WYRXIEUFRVSVEM-UHFFFAOYSA-N, ethyl 3-methyl-5-oxo-1-phenyl-4H-pyrazole-4-carboxylate, 2-Pyrazoline-4-carboxylic acid, 3-methyl-5-oxo-1-phenyl-, ethyl ester, AC1LCX19, SCHEMBL9147672, CTK8I0714, DTXSID00345943, MolPort-027-947-528, ALBB-031753, AKOS016013660, 1H-Pyrazole-4-carboxylic acid, 4,5-dihydro-3-methyl-5-oxo-1-phenyl-, ethyl ester, AX8249493, KB-253027, 1-phenyl-3-methyl-4-carbethoxy-2-pyrazolin-5-one, 3-Methyl-5-oxo-1-phenyl-2-pyrazoline-4-carboxylic acid ethyl ester, Ethyl3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-carboxylate, Ethyl 3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazole-4-carboxylate #

ID: 2540

chemical graph of compound 2540



InChIKey: WYUYEJNGHIOFOC-NWBUNABESA-N
SMILES: CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5702129
synonyms found at PubChem are:
Triprolidine hydrochloride, 550-70-9, Actidilat, Venen, Pro-Actidil, Pro-Entra, Entra, Triprolidine hydrochloride anhydrous, Triprolidine HCL, UNII-NG7A104R3J, 6138-79-0, trans-Triprolidine hydrochloride, EINECS 208-985-0, MLS000028751, NG7A104R3J, CHEBI:84119, 295 C 51, Actidilon, Triprolidine Hydrochloride (anhydrous), SMR000058521, (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, (E)-2-(3-(Pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride, trans-2-(3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)pyridine monohydrochloride, Pyridine, 2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride, (E)-, Triprolidine Monohydrochloride, trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, 486-12-4 (Parent), Pyridine, 2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-, monohydrochloride, (E)-, Pyridine, 2-((1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride, SR-01000075292, C19H22N2.HCl, triprolidine hydrochloride (anh.), T 6764, Prestwick_575, 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine hydrochloride, AC1NWAR4, Opera_ID_1214, Pyridine, 2-((1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl)-, hydrochloride (1:1), SCHEMBL42145, MLS001148254, MLS002207213, MLS002222226, SPECTRUM1500598, CHEMBL1200450, DTXSID10872513, Triprolidine hydrochloride hydrate, MolPort-003-666-303, HMS1568F06, HMS1921I07, Pharmakon1600-01500598, Triprolidine hydrochloride, >=99%, Tox21_501130, CCG-40331, MFCD00039044, NSC757361, triprolidine monohydrochloride (anh.), AKOS015962154, LP01130, NSC-757361, triprolidine monohydrochloride anhydrous, NCGC00094397-01, NCGC00094397-02, NCGC00094397-03, NCGC00261815-01, AC-15905, AS-13971, triprolidine monohydrochloride (anhydrous), LS-131942, EU-0101130, FT-0082802, V1639, 295C51, 138T790, SR-01000075292-1, SR-01000075292-3, SR-01000075292-7, Triprolidine hydrochloride, Sigma Reference Standard, trans-2-[3-(1-Pyrrolidinyl)-1-(p-tolyl)propenyl]pyridine Hydrochloride, (E)-2-[1-(4-METHYLPHENYL)-3-(1-PYRROLIDINYL)-1-PROPENYL]PYRIDINE HYDROCHLORIDE, 1-[(2E)-3-(4-methylphenyl)-3-(pyridin-2-yl)prop-2-en-1-yl]pyrrolidinium chloride, 2-[(1E)-1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]pyridine Hydrochloride, 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine hydrochloride, trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene Hydrochloride, 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine chloride, AC1O5G9Y

ID: 2541

chemical graph of compound 2541



InChIKey: WYWHKKSPHMUBEB-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1)C(=S)N=C(N2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1537
synonyms found at PubChem are:
6-Thioguanine, thioguanine, 154-42-7, Tioguanine, 2-Amino-6-mercaptopurine, 6-Mercaptoguanine, Tioguanin, Tabloid, Lanvis, 2-Amino-6-purinethiol, 2-Aminopurine-6-thiol, 2-Amino 6MP, 2-Aminopurin-6-thiol, Wellcome U3B, 2-Aminopurine-6(1H)-thione, Tioguaninum, 6-Mercapto-2-aminopurine, 2-Amino-9H-purine-6-thiol, 6-TG, 2-Amino-6-merkaptopurin, Guanine, thio-, Tioguanina, 2-Thioguanine, 6H-Purine-6-thione, 2-amino-1,7-dihydro-, BW 5071, Purine-6-thiol, 2-amino-, Purine-6(1H)-thione, 2-amino-, 2-Amino-6-MP, 2-Amino-1,7-dihydro-6H-purine-6-thione, Tioguaninum [INN-Latin], 2-Amino-1,9-Dihydro-6h-Purine-6-Thione, 2-Aminopurin-6-thiol [Czech], TG, Guanine, thio- (VAN), NSC 752, NSC-752, 2-Amino-1,7-dihydro-6H-purin-6-thion, 2-Amino-6-merkaptopurin [Czech], X 27, 6-Thioguanine (6-TG), Thioguanine [USAN:BAN], Tioguanina [INN-Spanish], UNII-WIX31ZPX66, THG, 2-amino-3,7-dihydropurine-6-thione, Thioguanine Hemihydrate, Tioguanine (INN), Lanvis (TN), CCRIS 8997, 9H-Purine-6-thiol, 2-amino-, HSDB 2504, EINECS 205-827-2, 2-Amino-1,7-dihydro-6H-purin-6-thion [Czech], CHEMBL727, WIX31ZPX66, 2-amino-6,7-dihydro-3H-purine-6-thione, AI3-26078, CHEBI:9555, NSC752, 7H-Purine-6-thiol, 2-amino-, WYWHKKSPHMUBEB-UHFFFAOYSA-N, Tioguanine [INN], 2-amino-1,7-dihydropurine-6-thione, 2-amino-1,9-dihydropurine-6-thione, 1H-Purine-6-thiol, 2-amino- (9CI), NCGC00094792-01, DSSTox_CID_3652, purine antimetabolite: antimetabolite: inhibits nucleic acid replication, DSSTox_RID_77129, DSSTox_GSID_23652, 6H-Purine-6-thione, 2-amino-3,7-dihydro- (9CI), ThioguaninGSK, 6 Thioguanine, Thioguanin GSK, Thioguanin-GSK, 6-Tioguanine, Thioguanine Tabloid, Tioguanina Wellcome, 153981-51-2, 153981-52-3, 154034-61-4, 154034-62-5, CAS-154-42-7, DX4, SMR000857244, 2 Amino 6 Purinethiol, SR-05000002077, Thioguanine [USAN:USP], Thioguanine Monosodium Salt, Thioquanine, 6-thioguanidine, 6-thioguano-sine, 6-TG/Thioguanine, PubChem9185, 6-Thioguanine/6-TG, Spectrum_000235, Guanine, thio-(VAN), ACMC-209dan, Tioguanina[INN-Spanish], Spectrum2_000695, Spectrum3_000577, Spectrum4_000926, Spectrum5_001455, 2-Amino-6-mercapto-purin, D02ZXM, 6-Thioguanine, Thioguanine, 6-Thioguanine, >=98%, SCHEMBL3701, SCHEMBL5898, NCIOpen2_004153, Thioguanine (Guanine analog), BSPBio_001994, C5H7N5S, KBioGR_001452, KBioGR_002476, KBioSS_000715, KBioSS_002483, 6-Thioguanine, 98% 1g, KSC491M3F, MLS001333131, MLS001333132, MLS006010896, Wellcome Brand of Thioguanine, DivK1c_000428, SPECTRUM1500573, SPBio_000849, 154-42-7|6-Thioguanine, 2-amino-6-mercapto-9H-purine, AC1MC379, GTPL6845, Thioguanine (TN) (GlaxoSmith), 5580-03-0 (hemihydrate), DTXSID6023652, Tioguanine GlaxoSmithKline Brand, CTK3J1632, HMS501F10, KBio1_000428, KBio2_000715, KBio2_002476, KBio2_003283, KBio2_005044, KBio2_005851, KBio2_007612, KBio3_001494, KBio3_002954, cMAP_000061, MolPort-000-929-106, MolPort-001-813-204, MolPort-003-665-495, NINDS_000428, BCPE000001, HMS1921E09, HMS2092M11, HMS2235F05, Pharmakon1600-01500573, Glaxo Wellcome Brand of Tioguanine, 2- degrees +/->>u-6-UIaNssE, 2-amino-1H-purine-6(9H)-thione, ALBB-023493, BCP27718, Glaxo Wellcome Brand of Thioguanine, GlaxoSmithKline Brand of Tioguanine, ZINC6382803, GlaxoSmithKline Brand of Thioguanine, Tox21_111035, Tox21_113184, Tox21_202401, Tox21_300275, ABP000905, ANW-21501, BDBM50200099, CCG-39890, CT-117, LS-888, MFCD00233553, NSC757348, s1774, SBB067147, 2- degrees +/->>u-6UI>>uaNssE, 76078-67-6 (mono-Na salt), AKOS003389499, AKOS015901298, AKOS023778741, Tox21_111035_1, 2-Amino-1,7-dihydro-purine-6-thione, 2-Amino-1,9-dihydro-purine-6-thione, AC-8421, AN-8030, API0015888, BCP9000197, CCG-213953, CS-1497, DB00352, FCH1448907, MCULE-5787306636, NSC-757348, PS-5007, RP02522, VZ33872, WLN: T56 BNM FYM INJ FUS HZ, IDI1_000428, SMP2_000326, NCGC00094792-02, NCGC00094792-03, NCGC00094792-05, NCGC00094792-06, NCGC00188976-01, NCGC00188976-02, NCGC00254082-01, NCGC00259950-01, NCGC00263442-01, 2-amino-1,7-dihydro-6h-purine-6-thion, 4CA-0085, AC-23020, CJ-15826, H351, HY-13765, KB-82699, NCI60_041643, SC-01333, SMR004701808, 2-amino-3,7-dihydro-6H-purine-6-thione, SBI-0051533.P003, AB0013003, AB2000285, FT-0083572, FT-0611217, LT00455187, R2215, ST45025337, Y7662, 2-Amino-1,7-dihydro-6H-purine-6-thione #, C07648, D08603, J10163, W-5092, 15151-EP2275420A1, 15151-EP2295055A2, 15151-EP2295416A2, 15151-EP2295426A1, 15151-EP2295427A1, 15151-EP2298748A2, 15151-EP2298764A1, 15151-EP2298765A1, 15151-EP2305642A2, 15151-EP2308833A2, 15151-EP2311453A1, 15151-EP2311808A1, 15151-EP2311825A1, 15151-EP2311829A1, 15151-EP2311840A1, 15151-EP2311842A2, 15151-EP2316832A1, 15151-EP2316833A1, AB00174074_06, AB00918694_06, AB01273926-01, AB01273926-02, AB01273926_03, 120118-EP2270008A1, 120118-EP2272827A1, 120118-EP2292617A1, 120118-EP2298778A1, 154T427, I14-1541, SR-05000002077-1, SR-05000002077-5, W-108030, W-205813, I14-18698, Z2768769146, Thioguanine, United States Pharmacopeia (USP) Reference Standard, 157646-93-0, 6-Thioguanine, Hybri-Max(TM), 50 x, gamma-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

ID: 2542

chemical graph of compound 2542



InChIKey: WZAUFGYINZYCKH-JJWQIEBTSA-N
SMILES: CC1=C2CC=C3[C@](C2=CC(=C1O)O)(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10411574
synonyms found at PubChem are:
dihydrocelastrol, Triptohypol C, CHEMBL1092797, SCHEMBL18850315, CHEBI:132340, MolPort-044-811-218, 2,3-Dihydroxy-24-norfriedela-1(10),2,4,7-tetrene-29-oic acid, (2R,4aS,6aS,12bS,14aS,14bR)-10,11-dihydroxy-2,4a,6a,9,12b,14a-hexamethyl-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid

ID: 2543

chemical graph of compound 2543



InChIKey: WZBWBNCQUTXYEL-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(F)(F)F)N2C=CN=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1359
synonyms found at PubChem are:
Trim, 25371-96-4, 1-(2-Trifluoromethylphenyl)imidazole, 1-[2-(trifluoromethyl)phenyl]imidazole, 1-(2-(Trifluoromethyl)phenyl)-1H-imidazole, 1-[2-(Trifluoromethyl)phenyl]-1H-imidazole, CHEMBL277525, WZBWBNCQUTXYEL-UHFFFAOYSA-N, IN1441, NCGC00016047-03, 1H-Imidazole,1-[2-(trifluoromethyl)phenyl]-, DSSTox_CID_25217, DSSTox_RID_80756, DSSTox_GSID_45217, [2-(trifluoromethyl)phenyl]imidazole, 1-TRIM, CAS-25371-96-4, SR-01000076173, PubChem6489, Tocris-0919, ACMC-1CKKY, AC1L1BAW, AC1Q4JVD, Lopac-T-7313, D0B3AR, Lopac0_001200, BSPBio_001344, BSPBio_002476, KBioGR_000064, KBioSS_000064, MLS002153350, SPECTRUM1505102, GTPL4331, SCHEMBL1322071, DTXSID9045217, CTK4F5577, KBio2_000064, KBio2_002632, KBio2_005200, KBio3_000127, KBio3_000128, PC7718E, CHEBI:109530, MolPort-000-159-086, Bio2_000064, Bio2_000544, HMS1361D06, HMS1791D06, HMS1989D06, HMS2231J13, HMS3263P21, HMS3267C09, HMS3373H08, HMS3402D06, ZINC156214, KS-000012QV, ZX-AP000617, Tox21_110289, Tox21_501200, 8459AD, BDBM50099401, MFCD00041206, SBB094614, 1-(2-trifluoromethylphenyl) imidazole, AKOS015852668, Tox21_110289_1, 2-(trifluoromethyl)phenyl-1H-imidazole, CCG-205274, LP01200, MCULE-8605426530, PS-7992, ACM25371964, IDI1_033814, NCGC00016047-01, NCGC00016047-02, NCGC00016047-04, NCGC00016047-05, NCGC00016047-06, NCGC00016047-07, NCGC00016047-08, NCGC00016047-09, NCGC00016047-11, NCGC00024873-01, NCGC00024873-02, NCGC00024873-03, NCGC00024873-04, NCGC00024873-05, NCGC00024873-06, NCGC00024873-07, NCGC00261885-01, KB-63874, SMR001230755, ST075546, ZB006249, 1-(2-Trifluoromethyl-phenyl)-1H-imidazole, DB-018471, TR-030752, B6504, EU-0101200, FT-0607096, 1-[2-(Trifluoromethyl)phenyl]-1H-imidazole #, 1H-Imidazole, 1-(2-(trifluoromethyl)phenyl)-, T 7313, SR-01000076173-1, SR-01000076173-3, BRD-K36851334-001-03-0, BRD-K36851334-001-05-5, BRD-K36851334-001-11-3

ID: 2544

chemical graph of compound 2544



InChIKey: WZHJKEUHNJHDLS-QTGUNEKASA-N
SMILES: CN1C[C@@H](C[C@H]2[C@H]1CC3=CN(C4=CC=CC2=C34)C)CNC(=O)OCC5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 28693
synonyms found at PubChem are:
metergoline, Liserdol, Metergolin, 17692-51-2, Methergoline, Metergolina, Metergolinum, Metergolina [DCIT], Metergolinum [Latin], Metergolina [Spanish], Metergoline [INN:BAN], Substance 355/255, Metergolinum [INN-Latin], 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin, FI-6337, MLS000069437, C25H29N3O2, UNII-1501393LY5, AHR 3009, 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline, EINECS 241-686-3, 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline, FI 6337, D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline, SMR000059050, (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester, CHEMBL19215, CHEBI:64216, D-N-Carbobenzoxydihydro-1-methyllysergamine I, (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester, Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat, D-N-Carboxydihydro-1-methyllysergamine I benzyl ester, MCE, NCGC00017257-09, 1501393LY5, Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester, D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester, Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester, DSSTox_CID_22584, DSSTox_RID_80053, DSSTox_GSID_42584, Metergoline phenylmethyl ester, benzyl {[(8alpha)-1,6-dimethylergolin-8-yl]methyl}carbamate, D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline benzyl ester, (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid benzyl ester, [(8beta)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester, Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester, benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate, SR-01000000003, Liserdol (TN), Prestwick_657, Metergoline (INN), CAS-17692-51-2, Opera_ID_1642, Prestwick0_000364, Prestwick1_000364, Prestwick2_000364, Prestwick3_000364, Biomol-NT_000134, D0UA0I, D0UQ2X, UPCMLD-DP151, AC1L1FV1, Lopac0_000726, BSPBio_000487, GTPL133, cid_28693, MLS001148102, MLS002207142, SCHEMBL117882, REGID_for_CID_28693, SPBio_002408, BPBio1_000287, BPBio1_000537, DTXSID5042584, UPCMLD-DP151:001, BDBM30704, MolPort-001-794-640, WZHJKEUHNJHDLS-QTGUNEKASA-N, HMS1569I09, HMS2096I09, HMS2234H19, HMS3262A14, HMS3713I09, AC1Q6654, HY-B1033, ZINC3812975, Tox21_110808, Tox21_500726, MFCD00153829, AKOS015889165, Tox21_110808_1, API0003187, CCG-204811, CS-4551, DB13520, KS-1369, LP00726, NCGC00017257-05, NCGC00017257-06, NCGC00017257-07, NCGC00017257-08, NCGC00017257-10, NCGC00017257-11, NCGC00017257-14, NCGC00022834-04, NCGC00022834-05, NCGC00022834-06, NCGC00022834-07, NCGC00022834-08, NCGC00261411-01, LS-49541, ST056348, B6365, EU-0100726, D07218, M 3668, SR-01000075561, SR-01000000003-2, SR-01000000003-4, SR-01000000003-5, SR-01000000003-6, SR-01000075561-1, BRD-K56699285-001-03-7, BRD-K56699285-001-18-5, I01-17061, N-CBZ-[(8|A)-1,6-Dimethylergolin-8-yl]methylamine, N-Cbz-[(8beta)-1,6-Dimethylergolin-8-yl]methylamine, benzyl{[(8b)-1,6-dimethylergolin-8-yl]methyl}carbamate, benzyl {[(8beta)-1,6-dimethylergolin-8-yl]methyl}carbamate, Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester, Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI), [(8?)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester, [(8|A)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester, [[(8beta)-1,6-Dimethylergolin-8-yl]-methyl]carbamic acid phenylmethyl ester, Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester, Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI), Carbamic acid, N-[[(8b)-1,6-dimethylergolin-8-yl]methyl]-,phenylmethyl ester, (phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate, N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid (phenylmethyl) ester, N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid benzyl ester

ID: 2545

chemical graph of compound 2545



InChIKey: WZQQOXSHARXAID-UHFFFAOYSA-N
SMILES: CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 159830
synonyms found at PubChem are:
HEMATOPORPHYRIN DIHYDROCHLORIDE, 17696-69-4, Haematoporphyrin dihydrochloride, Apiabasilon, Vitamorell, Hematoporphyrin IX dihydrochloride, Ematoporfirina [Italian], Hematoporphyrin dichydrochloride, Hematoporphyrin (dihydrochloride), EINECS 241-699-4, MFCD00013470, 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionic acid 2HCl, Acido 1,3,5,8-tetrametil-2,4-bis(idrossietil)porpfina-6,7-dipropionico dicloridrato, 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride, 21H,23H-Porphine-2,18-propanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, 2HCl, 3,3'-[7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl]dipropanoic acid dihydrochloride, Ematoporfirina, Hematoporphyrin HCl, 2,18-Porphinedipropionic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride, 670-69-9, Photodyn, Sensibion, AC1L4MK8, SPECTRUM700024, SCHEMBL498346, SCHEMBL498777, C34H40Cl2N4O6, AC1Q3B19, Hematoporphyrin(dihydrochloride), CHEMBL1319648, CTK5C5692, HY-B0754A, MolPort-003-665-943, 9281AA, CCG-38689, AKOS015911627, CS-5467, KS-00001F93, NCGC00095869-01, NCGC00095869-02, NCGC00095869-03, AK114600, LS-118321, FT-0626880, H-1450, I14-38030, 20456-06-8, 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride (1:2), 3-[18-(2-carboxyethyl)-8,13-bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid dihydrochloride, 50894-54-7, 5256-78-0

ID: 2546

chemical graph of compound 2546



InChIKey: WZUVPPKBWHMQCE-XJKSGUPXSA-N
SMILES: C1C2=CC(=C(C=C2[C@H]3[C@@]1(COC4=C3C=CC(=C4O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 442514
synonyms found at PubChem are:
HEMATOXYLIN, Haematoxylin, Hematoxyline, Hydroxybrazilin, (+)-Hematoxylin, 517-28-2, Hydroxybrasilin, Natural Black 1, UNII-YKM8PY2Z55, (+)-haematoxylin, Hydroxylrasilin, CCRIS 5916, HSDB 4174, EINECS 208-237-3, NSC 270085, YKM8PY2Z55, CHEBI:5601, CHEMBL477197, NCI-C55889, Hematoxylin hydrate, (6aS,11bR)-7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, Benz(b)indeno(1,2-d)pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, cis-(+)-, 1412-19-7, Hematoxylin Solution, Mayer's, hematoxiline, Hematoxylin Solution, Gill No. 1, Hematoxylin Solution, Harris Modified, (6aS,11bR)-7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol, cis-(+)-7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, cid_10603, Haematoxylin (C.I. 75290), cis-(+)-7,11b-dihydrobenz[b]indeno(1,2-d)pyran-3,4,6a,9,10(6H)-pentol, Benz(b)indeno(1,2-d)pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, (6aS,11bR)-, C.I. 75290, Hematoxylin n-Hydrate, Hematoxylin, certified, Hematoxylin n-Hyd rate, AC1L9CZN, SCHEMBL19654, Hematoxylin (Hydroxybrazilin), KS-00000YFS, BIH6002, MolPort-002-507-295, WZUVPPKBWHMQCE-XJKSGUPXSA-N, ZX-AFC000423, HMS3656K13, ZINC155806, HY-N0116, BDBM50263183, LMPK12100063, LS-168, MFCD00078111, s2384, AKOS016843524, CS-5341, MCULE-1559740273, NCGC00160144-01, AJ-13634, AK-42042, M546, Hematoxylin monohydrate, SAJ special grade, AX8110108, C.I.75290, ST24030751, C09931, Y-8982, Hematoxylin, certified by the Biological Stain Commission, Hematoxylin solution A according to Weigert, for microscopy, Hematoxylin solution according to Delafield, for microscopy, Hematoxylin, for microscopy (Hist.), indicator (pH 5.0-6.0), (6aS)-7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol, (6aS,11bR)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,4,6a,9,10-pentol, 7,11bbeta-Dihydrobenz[b]indeno[1,2-d]pyran-3,4,6abeta,9,10(6H)-pentol, Hematoxylin solution A according to Weigert, hematoxylin solution 100 g/l, (6aS,11bR)-6,6a,7,11b-tetrahydroindeno[2,1-c]chromene-3,4,6a,9,10-pentaol, (6aS,11bR)-7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentaol, Benz(b)indeno(1,2-d)pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro- (VAN), Benz(b)indeno(1,2-d)pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro- (VAN) (8CI), Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-,(6aS,11bR)-, (1R,10S)-8-oxatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2,4,6,12(17),13,15-hexaene-5,6,10,14,15-pentol, 22562-63-6

ID: 2547

chemical graph of compound 2547



InChIKey: XACKNLSZYYIACO-DJLDLDEBSA-N
SMILES: CCC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 66377
synonyms found at PubChem are:
edoxudine, 5-Ethyl-2'-deoxyuridine, 2'-Deoxy-5-ethyluridine, 15176-29-1, 5-Ethyldeoxyuridine, Epoxudine, Aedurid, Edoxudinum [Latin], Edoxudina [Spanish], EUDR, Edoxudin, beta-5-Ethyldeoxyuridine, Edoxudine [USAN:INN], UNII-15ZQM81Y3R, beta-5-Ethyl-2'-deoxyuridine, Uridine, 2'-deoxy-5-ethyl-, CCRIS 2349, EINECS 239-226-1, ORF 15817, RWJ 15817, BRN 0755089, MLS000069564, 15ZQM81Y3R, CHEMBL318153, 5-Ethyl-1-(2'-deoxy-beta-D-ribofuranosyl)uracil, SMR000058816, Edoxudinum, C11H16N2O5, Edoxudina, EDU, 46895-01-6, ORF-15817, RWJ-15817, EtUdR, 5-Ethyl-dUrd, Edoxudine (USAN/INN), Opera_ID_1297, D0Y4MD, 5-ethyl-2''-deoxyuridine, cid_1814, DSSTox_CID_25890, DSSTox_RID_81204, DSSTox_GSID_45890, SCHEMBL65579, cid_66377, MLS001076558, AC1L258O, 5-ethyl-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, DTXSID4045890, CTK4I9625, CHEBI:135051, XACKNLSZYYIACO-DJLDLDEBSA-N, HMS2234L05, HY-B1011, ZINC3956771, Tox21_111390, BDBM50132292, MFCD00079191, uridine-4-14C-2'-deoxy-5-ethyl-, AKOS027320600, CS-4524, DB13421, 5-ethyl-1-(2'-deoxyribofuranosyl)uracil, CAS-15176-29-1, LS-160818, FT-0772436, D03956, 1-(2'-deoxy-beta-D-ribofuranosyl)-5-ethyluracil, 5-Ethyl-2 inverted exclamation mark -deoxyuridine, BRD-K86892782-001-13-9, 5-ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 5-ethyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 5-Ethyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 5-Ethyl-1-((2R,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione, 5-ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, 69264-36-4

ID: 2548

chemical graph of compound 2548



InChIKey: XAEWZDYWZHIUCT-UHFFFAOYSA-N
SMILES: CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 65327
synonyms found at PubChem are:
Desipramine hydrochloride, 58-28-6, Norpramin, Desipramine Hcl, Pertofrane, Pertofran, DMI hydrochloride, Norpolake, Nortimil, Desmethylimipramine chloride, Pertofrin, Petylyl, Desipramine monohydrochloride, Demethylimipramine hydrochloride, Imipraminedemethyl hydrochloride, Desmethylimipramine hydrochloride, Desimipramine, hydrochloride, Desmethylimipramine monohydrochloride, EX 4355, RMI 9,384A, UNII-1Y58DO4MY1, NSC-114901, JB 8181, G-35020, EINECS 200-373-1, G 35020, NSC 114901, JB-8181, N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride, MLS000028418, 1Y58DO4MY1, CHEBI:4449, 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride, 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride, GMI, CPD000036827, SMR000036827, Norpramin (TN), 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride, DSSTox_CID_26942, DSSTox_RID_82024, DSSTox_GSID_46942, 10,11-Dihydro-N-methyl-5H-dibenz-[b,f]azepine hydrochloride, 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride, EX-4355, CAS-58-28-6, SR-01000003060, NCGC00015340-02, iren, Desiprimine, Pertrofan, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine;hydrochloride, Prestwick_706, Desipramine hydrochloride [USAN:JAN], 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride, Desipramine hydrochloride [USAN:USP:JAN], Despiramine hydrochloride, Opera_ID_943, Desimipramine hydrochloride, Epitope ID:224551, 10,f]azepine hydrochloride, CHEMBL1696, SCHEMBL41992, MLS000038088, MLS001056757, MLS002222246, MLS002548871, 50-47-5 (Parent), SPECTRUM1500227, REGID_for_CID_65327, 10,f]azepine monohydrochloride, Desmethylimipramine-hydrochloride, DTXSID9046942, CTK8F9062, RMI-9384A, MolPort-000-917-727, XAEWZDYWZHIUCT-UHFFFAOYSA-N, HMS1569E07, HMS1920C22, Pharmakon1600-01500227, AC1L2324, HY-B1272, Tox21_110129, Tox21_500358, AN-083, BG0162, CCG-38909, Desipramine hydrochloride (JAN/USP), MFCD00058108, NSC114901, NSC756719, AKOS015994722, Tox21_110129_1, CS-8201, KS-1296, LP00358, NC00681, NSC-756719, VA10690, 58-28-6 (HCl), NCGC00015340-14, NCGC00093794-01, NCGC00093794-02, NCGC00093794-03, NCGC00093794-04, NCGC00093794-05, NCGC00261043-01, CC-26348, LS-60422, SAM002264605, SC-57976, WLN: T C676 BN&T&J B3M1 &GH, B7261, EU-0100358, FT-0603109, D 3900, D00812, Desipramine hydrochloride, >=98% (TLC), powder, SR-01000003060-2, SR-01000003060-8, N-(.gamma.-Methylaminopropyl)iminodibenzyl hydrochloride, 5H-Dibenz[b, 10,11-dihydro-N-methyl-, monohydrochloride, 5-(3-Methylaminopropyl)-5H-dibenz[b,f]azepine hydrochloride, Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base), 5H-Dibenz[b, 10,11-dihydro-5-[3-(methylamino)propyl]-, hydrochloride, 5H-Dibenz[b, 10,11-dihydro-5-[3-(methylamino)propyl]-, monohydrochloride, Desipramine hydrochloride solution, drug standard, 1.0 mg/mL in methanol, Desipramine hydrochloride, European Pharmacopoeia (EP) Reference Standard, 10,11-Dihydro-5-(3-(methylamino)prop-yl)-5h-dibenz(b,f)azepine hydro-chloride, 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride, Desipramine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Desipramine hydrochloride, United States Pharmacopeia (USP) Reference Standard, AC1LCWD4, AKOS026749995, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine; hydron; chloride, MolPort-000-737-809, AKOS024282154, MCULE-1872169026, ST053524, (3-(10H,11H-dibenzo[b,f]azepin-5-yl)propyl)methylamine, chloride

ID: 2549

chemical graph of compound 2549



InChIKey: XAUWSIIGUUMHQQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=NN=C(N=N2)C3=CC=CC=C3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 23263
synonyms found at PubChem are:
3,6-Diphenyl-1,2,4,5-tetrazine, 6830-78-0, Diphenyl-s-tetrazine, 3,6-Diphenyl-s-tetrazine, 3,6-Diphenyltetrazine, 1,2,4,5-TETRAZINE, 3,6-DIPHENYL-, s-Tetrazine, 2,6-diphenyl-, s-Tetrazine, 3,6-diphenyl-, NSC 73054, 3,6-Diphenyl-sym-tetrazine, MLS000736800, XAUWSIIGUUMHQQ-UHFFFAOYSA-N, NSC73054, ACMC-1BAEF, HEP1NA5YSD, UNII-HEP1NA5YSD, Enamine_004961, AC1L2LZA, s-Tetrazine,6-diphenyl-, NCIOpen2_003742, CHEMBL17784, diphenyl-1,2,4,5-tetrazine, SCHEMBL3652642, CTK8B2156, DTXSID10218457, MolPort-000-792-259, HMS1408B11, HMS2780N06, ZINC350319, 1,4,5-Tetrazine, 3,6-diphenyl-, ANW-35475, NSC-73054, STK177320, 3,6-Diphenyl-1,2,4,5-tetraazine, 1,2,4,5-Tetrazine,3,6-diphenyl-, 3,6-Diphenyl-[1,2,4,5]tetrazine, AKOS000369904, s-Tetrazine, 3,6-diphenyl- (8CI), MCULE-2427196575, IDI1_007548, 3,6-Diphenyl-1,2,4,5-tetraazine #, NCGC00246946-01, SMR000447024, ZB011060, 3,6-Diphenyl-1,2,4,5-tetrazine, 98%, DB-055132, KB-179943, LS-149030, TC-124220, D3175, FT-0614772, ST45236389, AF-215/00262032, I14-49644, Z56871597

ID: 2550

chemical graph of compound 2550



InChIKey: XAXVWWYPKOGXSY-PVFNKAEGSA-N
SMILES: C1=CC(=CC=C1[C@@H]2[C@@H](C3=CC(=CC4=C3[C@@H]([C@H](O4)C5=CC=C(C=C5)O)C6=CC(=CC(=C26)O)O)O)C7=C(C=CC(=C7)/C=C/C8=CC(=CC9=C8[C@@H]([C@H](O9)C1=CC=C(C=C1)O)C1=CC(=CC(=C1)O)O)O)O)O

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"T Ma" "Y Sui" "H Yang" "X Gao" "B Yu" "Y Zhang"


CID is 44251742
synonyms found at PubChem are:
r-2-Viniferin, SCHEMBL14255843

ID: 2551

chemical graph of compound 2551



InChIKey: XBCNMKREIWPKPG-UHFFFAOYSA-N
SMILES: COC1=CC=CC2=C1OC(=C(C2=O)OC)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708667
synonyms found at PubChem are:
KBio1_001423, SpecPlus_000383, AC1O8FID, Spectrum2_001358, Spectrum5_001784, DivK1c_006479, SPBio_001575, SCHEMBL4282126, CCG-38840, 3,8-dimethoxy-2-phenylchromen-4-one, SDCCGMLS-0066607.P001

ID: 2552

chemical graph of compound 2552



InChIKey: XBEFQTHUADKZEH-AWEZNQCLSA-N
SMILES: CC(=O)OC(C)(C)[C@@H]1CC2=C(O1)C=C3C(=C2)C=CC(=O)O3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708816
synonyms found at PubChem are:
MARMESIN ACETATE, 2-[(2S)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, KBio2_004566, Spectrum_001518, SpecPlus_000942, AC1O8FQT, Spectrum2_001212, Spectrum3_001643, Spectrum4_001784, Spectrum5_000427, BSPBio_003365, KBioGR_002329, KBioSS_001998, DivK1c_007038, SPECTRUM1504163, SPBio_001024, CHEMBL3039390, SCHEMBL12062110, KBio1_001982, KBio2_001998, KBio2_007134, KBio3_002585, MolPort-002-321-253, ZINC3203266, CCG-40075, STK368478, AKOS005444354, MCULE-8125910719, SDCCGMLS-0066750.P001, BRD-K57001030-001-02-5, 2-[(2S)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-2-yl]propan-2-yl acetate

ID: 2553

chemical graph of compound 2553



InChIKey: XBOZTWUGBRZVBP-UHFFFAOYSA-N
SMILES: C1CCC(CC1)(C2=CC3=CC=CC=C3S2)N4CCCCC4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957484
synonyms found at PubChem are:
BTCP hydrochloride, SR-01000075730, EU-0100226, CHEMBL1255586, Tox21_500226, CCG-221530, LP00226, NCGC00093694-01, NCGC00260911-01, B-138, SR-01000075730-1, N-[1-(Benzo[b]thien-2-yl-cyclohexyl)]piperidine hydrochloride, 1-[1-(2-benzo[b]thiopheneyl)cyclohexyl]piperidine hydrochloride

ID: 2554

chemical graph of compound 2554



InChIKey: XBTIPIZROJAKOJ-UHFFFAOYSA-M
SMILES: C1=CC(=CN=C1)CC2=CC3=C(C=C2)OC(=C3)C(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 55715
synonyms found at PubChem are:
FUREGRELATE SODIUM, 85666-17-7, U-63557A, U 63557A, UNII-4F11B27M90, 5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium, Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate, 4F11B27M90, NCGC00016149-03, 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt, Furegrelate sdium, Lopac-F-3764, DSSTox_CID_25226, DSSTox_RID_80763, DSSTox_GSID_45226, C15H10NO3.Na, CHEMBL36028, SCHEMBL635010, SPECTRUM1501195, DTXSID8045226, CTK8F9966, HMS500M17, MolPort-003-666-385, HMS1921P11, HMS3261H11, HMS3649O07, Furegrelate Sodium (U-63557A), Tox21_110310, Tox21_500515, 1774AH, CCG-39186, LP00515, NCGC00016149-01, NCGC00016149-02, NCGC00016149-04, NCGC00093910-01, NCGC00093910-02, NCGC00093910-03, NCGC00261200-01, CAS-87463-91-0, LS-186800, EU-0100515, FT-0727090, 5-[3-Pyridinylmethyl]benzo-furancarboxylic acid, F 3764, 5-[3-Pyridinylmethyl]benzo- furancarboxylic acid, C-46211, 5-(3-Pyridinylmethyl)benzofurancarboxylic acid sodium, sodium 5-(pyridin-3-ylmethyl)benzofuran-2-carboxylate, potassium 5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylate

ID: 2555

chemical graph of compound 2555



InChIKey: XCSGPAVHZFQHGE-UHFFFAOYSA-N
SMILES: CCC1=C(C(=CC=C1)CC)N(COC)C(=O)CCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2078
synonyms found at PubChem are:
alachlor, 15972-60-8, Lasagrin, Metachlor, Methachlor, Alanex, Alachlore, Alochlor, Pillarzo, Lasso, Chimiclor, Alanox, LAZO, Lasso micro-tech, 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide, alapaz, Alatox 480, 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide, Alachlor technical, Alachlor [ANSI:BSI:ISO], Caswell No. 011, Acetamide, 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)-, Satochlor, Nitala, Alachlore [ISO-French], CP 50144, UNII-24S2S61PXL, CCRIS 3155, HSDB 1014, 2-Chloro-N-(2,6-diethyl)phenyl-N-methoxymethylacetamide, Alachlor technical (90% or more), N-(Methoxymethyl)-2,6-diethylchloroacetanilide, EINECS 240-110-8, EPA Pesticide Chemical Code 090501, BRN 2944476, alpha-Chloro-2',6'-diethyl-N-methoxymethylacetanilide, Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid, AI3-51506, 24S2S61PXL, Acetanilide, 2-chloro-2',6'-diethyl-N-(methoxymethyl)-, CHEBI:2533, XCSGPAVHZFQHGE-UHFFFAOYSA-N, ALACHLOR (PESTICIDES MIXTURE), Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid [German], DSSTox_CID_2265, DSSTox_RID_76532, DSSTox_GSID_22265, 2',6'-Diethyl-N-(methoxymethyl)-2-chloroacetanilide, 2-chloro-N-(2,6-diethylphenyl)-N-[(methyloxy)methyl]acetamide, CAS-15972-60-8, Perfect, Ralchlor, Alagan, Intrro, Lasso Microtech, Micro-Tech, Alachlor solution, Alachlor-atrazine, Spectrum_001859, SpecPlus_000470, AC1Q2UBK, Spectrum2_001853, Spectrum3_000835, Spectrum4_000675, Spectrum5_001984, AC1L1CV9, BIDD:PXR0027, SCHEMBL15501, BSPBio_002389, KBioGR_001109, KBioSS_002376, SPECTRUM330043, MLS002695955, BIDD:ER0383, DivK1c_006566, SPBio_001666, CHEMBL1414154, DTXSID1022265, KBio1_001510, KBio2_002372, KBio2_004940, KBio2_007508, KBio3_001889, XCSGPAVHZFQHGE-UHFFFAOYSA-, Alachlor 10 microg/mL in Acetone, HMS3091A18, ZINC900557, Tox21_202205, Tox21_300713, Alachlor 100 microg/mL in Methanol, CCG-39391, LS-909, AKOS015889908, Alachlor 10 microg/mL in Acetonitrile, MCULE-6800928097, VA10194, NCGC00090758-01, NCGC00090758-02, NCGC00090758-03, NCGC00090758-04, NCGC00090758-05, NCGC00090758-06, NCGC00090758-07, NCGC00090758-08, NCGC00090758-09, NCGC00254619-01, NCGC00259754-01, AJ-24302, CC-09821, SMR000777860, ZB015183, KB-230190, Alachlor, PESTANAL(R), analytical standard, FT-0657940, C10928, 972A608, C-35028, 2-Chloro-2',6'-diethyl-N-methoxymethylacetanilide, I01-4384, J-009637, 2-chloro-2', 6'-diethyl-N-(methoxymethyl)acetanilide, 2-chloro-2',6'-diethyl-N-(methoxymethyl) acetanilide, 2-Chloro-2',6'-diethyl-N-(methoxymethyl)-acetanilde, 2-chloro-2',6'-diethyl-N-(methoxymethyl)-acetanilide, BRD-K02548315-001-02-7, N-methoxymethyl-N-(2,6-diethylphenyl)chloroacetamide, N-(methoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide, 2-chloro-N-(methoxymethyl)-N-(2,6-diethyl-phenyl)-acetamide, 2-Chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide, 9CI, Acetamide, 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)- (9CI), Alachlor solution, certified reference material, 1000 mug/mL in methanol, 2-Chloro-2 inverted exclamation marka,6 inverted exclamation marka-diethyl-N-(methoxymethyl)acetanilide, InChI=1/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3

ID: 2556

chemical graph of compound 2556



InChIKey: XCSLJQFPTAZKDV-UHFFFAOYSA-N
SMILES: C1=CC(=C(C2=C(C(=O)C=C(C=C21)C(=O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5098885
synonyms found at PubChem are:
7-DESHYDROXYPYROGALLIN-4-CARBOXYLIC ACID, KBio3_002853, Spectrum_000215, SpecPlus_000103, Spectrum2_000174, Spectrum3_001796, Spectrum4_000893, Spectrum5_001656, AC1NP3I4, BSPBio_003351, KBioGR_001326, KBioSS_000695, DivK1c_006199, SPBio_000067, CHEMBL559337, SCHEMBL12609998, BDBM33413, KBio1_001143, KBio2_000695, KBio2_003263, KBio2_005831, CCG-39028, benzo[7]annulene-8-carboxylic acid, 5, NCGC00178123-01, 3,4,5-trihydroxy-6-oxobenzo[7]annulene-8-carboxylic acid, 1,2,8-Trihydroxy-9-oxo-9H-benzocycloheptene-6-carboxylic acid

ID: 2557

chemical graph of compound 2557



InChIKey: XDDAORKBJWWYJS-UHFFFAOYSA-N
SMILES: C(C(=O)O)NCP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3496
synonyms found at PubChem are:
glyphosate, 1071-83-6, N-(Phosphonomethyl)glycine, Glyphosphate, Roundup, Glycine, N-(phosphonomethyl)-, 2-(phosphonomethylamino)acetic acid, N-Phosphonomethyl-glycine, Pondmaster, Silglif, Roundup Max, N-Phosphonomethylglycine, N-Phosphomethylglycine, Caswell No. 661A, MON 2139, C3H8NO5P, N-(Phosphonomethyl) Glycine, NSC151063, Glialka, Mon 6000, Phosphonomethyliminoacetic acid, Glyphosate [ANSI:BSI:ISO], UNII-4632WW1X5A, CCRIS 1587, CP 67573, HSDB 3432, XDDAORKBJWWYJS-UHFFFAOYSA-N, EINECS 213-997-4, 2-((Phosphonomethyl)amino)acetic acid, EPA Pesticide Chemical Code 417300, NSC 151063, BRN 2045054, CHEMBL95764, Isopropylamine glyphosate, CHEBI:27744, 4632WW1X5A, N-(PHOSPHONOMETHYL)-GLYCINE, [(phosphonomethyl)amino]acetic acid, NSC-151063, MON 0573, (Phosphonomethyl)glycine, Q-201175, gliphosate, Buccaneer, Folusen, Glifoglex, Glyphomax, Herbatop, Kickdown, Phorsat, Accord, Atila, Forsat, Glyfos, Hockey, Klinik, Leone, Safal, ((phosphonomethyl)amino)acetic acid, Gliz, GlyGran, Buccaneer Plus, Rebel Garden, Glyphodin A, Glyphosate CT, Ground Bio, 2-[(phosphonomethyl)amino]acetic acid, MON 39, 994-61-6, Lancer (herbicide), Glialka 36, Glifosan 747, phosphonomethylglycine, C-K Yuyos FAV, (Carboxymethylamino)methylphosphonic acid, Gliz 480CS, CP 70139, 2gga, 2ggd, GPF, MON 3539, Roundup (TN), Carboxymethylaminomethanephosphinic acid, phosphonomethyl glycine, HM 2028, Spectrum_001867, SpecPlus_000478, GPJ, Spectrum2_001847, Spectrum3_000839, Spectrum4_000679, Spectrum5_001992, WLN: QV1M1PQQO, D04HMD, AC1L1G2E, NCIStruc1_000002, NCIStruc2_000104, SCHEMBL16440, BSPBio_002397, KBioGR_001117, KBioSS_002384, SPECTRUM330047, DivK1c_006574, SPBio_001634, Glyphosate, isopropylamine salt, AC1Q762I, GLY009, N-PHOSPHONOMETHYL GLYCINE, DTXSID1024122, CTK3I6546, Glyphosate 40% aqueous solution, KBio1_001518, KBio2_002380, KBio2_004948, KBio2_007516, KBio3_001897, XDDAORKBJWWYJS-UHFFFAOYSA-, BIG0158, MolPort-001-793-049, N-(Phosphonomethyl)glycine, 96%, ZX-AFC000444, Glyphosate 10 microg/mL in Water, 2-(Phosphonatomethylammonio)Acetate, EBD22819, KS-00000YT9, ZINC3872713, Glyphosate 100 microg/mL in Water, 2-(phosphonomethylamino)ethanoic acid, BDBM50281349, CCG-38069, LS-445, MFCD00055350, NCGC00014409, NCI151063, 70393-85-0 (hydrochloride salt), AKOS004915878, 40465-66-5 (mono-ammonium salt), AGR0000777, FCH1116885, KS-5110, MCULE-3308266821, RTR-001400, TRA0072527, NCGC00014409-02, NCGC00014409-03, NCGC00014409-04, NCGC00094536-01, NCGC00094536-02, NCGC00094536-03, 34494-03-6 (mono-hydrochloride salt), AJ-46368, AN-19669, CC-29058, NCI60_001060, SC-12224, AX8132329, TL8000254, TR-001400, FT-0083163, FT-0651304, GLYPHOSATE (SEE CAS 38641-94-0), Glyphosate, PESTANAL(R), analytical standard, 71G836, C01705, K-0555, 31301-EP2272846A1, 31301-EP2274983A1, 31301-EP2275422A1, 31301-EP2277868A1, 31301-EP2277869A1, 31301-EP2277870A1, 31301-EP2305655A2, 31301-EP2305658A1, 31301-EP2305662A1, 31301-EP2308858A1, 31301-EP2308866A1, 31301-EP2311815A1, 31301-EP2311816A1, 31301-EP2311817A1, 31301-EP2371823A1, 31301-EP2374791A1, A801602, C-35392, I14-2557, 86491FAD-2F76-4CDE-90EE-6131D3FCF0BB, Glyphosate, certified reference material, TraceCERT(R), N-(Phosphonomethyl)glycine, plant cell culture tested, BioReagent, Glyphosate (n-(phosphonomethyl)glycine) Solution, 100 mg/L, 1 mL (RM, ISO GUIDE 34), InChI=1/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9), 1585457-94-8, 37337-60-3, 42618-09-7, 75241-08-6

ID: 2558

chemical graph of compound 2558



InChIKey: XDHCWTUZCOFKRH-CIKBGXLUSA-N
SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 234102
synonyms found at PubChem are:
11-OXOURSOLIC ACID ACETATE, CHEMBL601891, 3-acetyl-11-keto-ursolic acid, 35959-01-4, NSC33403, D0J5RQ, AC1L5RI4, 3-O-acetyl-11-oxoursolic acid, MolPort-044-649-591, BDBM50307109, NSC-33403, AKOS016036264, (1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bS)-10-acetyloxy-1,2,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,5,6,6a,7,8,8a,10,11,12,14b-tetradecahydropicene-4a-carboxylic acid

ID: 2559

chemical graph of compound 2559



InChIKey: XDNGMMUZVUCMJZ-UHFFFAOYSA-N
SMILES: C1=CC=NC(=C1)C2=NOC(=C2)CO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 686542
synonyms found at PubChem are:
3-(2-pyridinyl)-5-isoxazolemethanol, 3-(pyridin-2-yl)-5-hydroxymethylisoxazole, 158840-78-9, AC1LEI3K, MLS001143950, SCHEMBL1314692, CHEMBL1326387, XDNGMMUZVUCMJZ-UHFFFAOYSA-N, HMS2213P12, HMS3350I19, AKOS022358382, SMR001196045, ST021152, (3-(Pyridin-2-yl)isoxazol-5-yl)methanol, (3-(2-pyridyl)isoxazol-5-yl)methan-1-ol, (3-pyridin-2-yl-1,2-oxazol-5-yl)methanol, 2-(5-Hydroxymethyl-isoxazol-3-yl)-pyridine

ID: 2560

chemical graph of compound 2560



InChIKey: XDROKJSWHURZGO-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"TH Ma" "H Yang" "WL Na" "SG Hou" "LN Xu" "X Liu" "S Lin"


CID is 10658
synonyms found at PubChem are:
Angelicin, ISOPSORALEN, 523-50-2, 2H-Furo[2,3-H]chromen-2-one, Angecin, furo[2,3-h]chromen-2-one, Isopsoralin, Furo(2,3-h)coumarin, Angelecin, Angelicin (coumarin derivative), 2H-Furo[2,3-H]-1-benzopyran-2-one, 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran, UNII-CZZ080D7BD, Angelicin (coumarin deriv), NSC 404563, CCRIS 4276, Furo(5',4':7,8)coumarin, HSDB 3554, 4-Hydroxy-5-benzofuranacrylic acid gamma-lactone, BRN 0153970, CZZ080D7BD, 2H-Furo(2,3-H)-1-benzopyran-2-one, CHEMBL53569, Furo[5',4':7,8]coumarin, 3-(4-Hydroxy-5-benzofuranyl)-2-propenoic acid gamma-lactone, CHEBI:28928, 2H-Furo(2,3-h)(1)benzopyran-2-one, Furo[2,3-h]coumarin, 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, delta-lactone, Q-100592, Isopsoralene, Isopsoralen,(S), Furo[5',8]coumarin, AS602868, D01OLO, D0S5KN, AC1L1VO2, AC1Q6BE0, Oprea1_022970, 5-19-04-00447 (Beilstein Handbook Reference), Angelicin, analytical standard, SCHEMBL376379, furano[2,3-h]chromen-8-one, Furo(5',4',7,8)coumarin, Furo[2,3-h]benzopyran-2-one, CTK1H0609, pyrano[6,5-e]benzofuran-2-one, ZINC73700, DTXSID00200321, MolPort-002-508-765, XDROKJSWHURZGO-UHFFFAOYSA-N, 2-furo[2,3-h][1]benzopyranone, HMS1645D18, HY-N0763, 2H-Furo[2,3-H]chromen-2-one #, BDBM50331545, FCH834801, MFCD00064930, NSC404563, AKOS006281380, API0000385, CS-3754, Furo[2,3-h]chromen-2-one(angelicin), MCULE-7782406452, NSC-404563, KS-00000N78, 4CN-1218, AJ-10295, AK111279, AN-45545, AS-35334, CC-29702, LS-70688, SC-47357, ST023306, ZB002644, AB0019705, AX8077901, KB-230742, TR-018581, FT-0603446, N1883, ST24041054, V0167, C09060, W-2783, 523I502, A829042, C-07477, 4-Hydroxy-5-benzofuranacrylic acid .gamma.-lactone, Angelicin plus ultraviolet A radiation [Angelicins], I06-0550, 3-(4-Hydroxy-5-benzofuranyl)-2-propenoic acid .gamma.-lactone, 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, .delta.-lactone, InChI=1/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6, 39310-13-9

ID: 2561

chemical graph of compound 2561



InChIKey: XDSHNNRBLSBDAP-SNAWJCMRSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)/C=C/C=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5839209
synonyms found at PubChem are:
3,4,5-Trimethoxycinnamaldehyde, UNII-0U9SB79TM1, 2-Propenal, 3-(3,4,5-trimethoxyphenyl)-, 3,4,5-Trimethoxycinnamic aldehyde, NSC 280793, BRN 1972155, CINNAMALDEHYDE, 3,4,5-TRIMETHOXY-, 0U9SB79TM1, 71277-13-9, 3-(3,4,5-Trimethoxyphenyl)-2-propenal, 34346-90-2, 2-Propenal, 3-(3,4,5-trimethoxyphenyl)-, (2E)-, 3-(3,4,5-trimethoxy-phenyl)-propenal, (E)-3,4,5-Trimethoxycinnamaldehyde, trans-3,4,5-Trimethoxycinnamaldehyde, 3,4,5-Trimethoxycinnamaldehyde, (E)-, AC1NYS9U, Spectrum5_000181, BSPBio_002891, SCHEMBL527350, 2-Propenal, 3-(3,4,5-trimethoxyphenyl)-, (E)-, CHEBI:113534, MolPort-003-665-680, ZINC1563660, CCG-38467, 3-(3,4,5-Trimethoxyphenyl)propenal, MCULE-2785937678, NCGC00178406-01, 3-(3,4,5-trimethoxyphenyl)acrylaldehyde, LS-53837, TL80073699, PK04_181168, (2E)-3-(3,4,5-trimethoxyphenyl)acrylaldehyde, (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enal, 2-Propenal, 3-(3,4,5-trimethoxyphenyl)- (9CI), BRD-K87194840-001-02-2, NCGC00178406-02!(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enal

ID: 2562

chemical graph of compound 2562



InChIKey: XDVMCVGTDUKDHL-UHFFFAOYSA-N
SMILES: C(CSC(=N)N)N.Br.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5940
synonyms found at PubChem are:
2-(2-Aminoethyl)isothiourea dihydrobromide, 56-10-0, Antiradon, Ixecur, Antirad, Surrectan, 2-aminoethyl carbamimidothioate dihydrobromide, aet, USAF XR-31, Carbamimidothioic acid, 2-aminoethyl ester, dihydrobromide, 2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide, UNII-03K18418PY, Aminoethylisothiuronium bromide hydrobromide, 2-Aminoethylisothiouronium dibromide, EINECS 200-257-0, NSC 22877, beta-Aminoethylisothiouronium bromide hydrobromide, 2-Aminoethylisothiuronium dihydrobromide, S-(2-Aminoethyl)isothiuronium dibromide, 2-Aminoethylthiopseudourea dihydrobromide, S-beta-Aminoethylisothiuronium bromohydrate, AI3-23427, S-(2-Aminoethyl)pseudothiourea dihydrobromide, S-Aminoethylisothiuronium bromide hydrobromide, 2-Aminoethylisothiuronium bromide hydrobromide, S-2-Aminoethylthiouronium bromide hydrobromide, 2-(2-Aminoethyl)-2-thiopseudourea hydrobromide, Isothiuronium bromide, aminoethyl-, hydrobromide, S-(2-Aminoaethyl)isothiuronium dibromid [German], S-2-Aminoethylisothiouronium bromide hydrobromide, A 15591, 2beta-Aminoethylisothiourea-bromide-hydrogen bromide, Pseudourea, (2-aminoethyl)-2-thio-, dihydrobromide, beta-Aminoaethyl-isothiuronium dihydrobromid [German], 2-(beta-Aminoethyl)isothiouronium bromide hydrobromide, 03K18418PY, A. E. T., 927-71-9, W-105530, S-(2-Aminoethyl)isothiouronium bromide hydrobromide, beta-Aminoethylisothiuronium Bromide, SR-01000075171, S-(2-Aminoethyl)Isothiourea Dihydrobromide, S-(2-Aminoethyl)isothiuronium bromide hydrobromide, S-(2-Aminoaethyl)isothiuronium dibromid, ACMC-20a6lf, beta-Aminoaethyl-isothiuronium dihydrobromid, AC1L1LGO, b-aminoethylisothiuronium bromide hydrobromide, C3H11Br2N3S, SPECTRUM1505119, AC1Q239V, 151-16-6 (parent cpd), CHEMBL1256182, DTXSID1058765, 63680-10-4 (diacetate), A. E. T, 871-25-0 (di-hydrochloride), MolPort-003-355-623, 63680-11-5 (diperchlorate), 63680-12-6 (di-hydriodide), Carbamimidothioic acid, 2-aminoethyl ester, hydrobromide (1:2), 2141-04-0 (mono-hydrobromide), EINECS 218-391-3, Tox21_500078, ANW-59473, MFCD00037011, AKOS015962093, 2-(2-Aminoethyl)isothiouronium bromide, API0001518, CCG-214521, FCH4758738, LP00078, NCGC00093585-01, NCGC00093585-02, NCGC00260763-01, AC-15654, AN-41679, BBV-75779280, M885, 2-AMINOETHYLISO-THIOURONIUM BROMIDE, 63680-13-7 (phosphate (1:1)), 18144-22-4 (sulfate (1:1)), KB-162291, LS-125996, RT-003226, S-(2-aminoethyl)isothiourea di-hydrobromide, EU-0100078, FT-0621931, A 5879, 2-AMINOETHYLISOTHISOTHIURONIUM BROMIDE HBR, S-(2-aminoethyl)isothiouronium bromide hydrobromi, S-(2-Aminoethyl)thiouronium bromide hydrobromide, 037A011, 2-(2-Aminoethyl)isothiourea dihydrobromide, 99%, (2-aminoethyl)sulfanylmethanimidamide dihydrobromide, AET; S-(2-Aminoethyl)isothiouronium dihydrobromide, SR-01000075171-1, SR-01000075171-3, SR-01000075171-7, 2-AMINOETHYLSULFANYLMETHANIMIDAMIDE DIHYDROBROMIDE, 2141-04-0, AKOS024387415, MCULE-2799536411, ST51040152, (2-aminoethyl)thiocarboxamidine, bromide, bromide, SCHEMBL524425, SCHEMBL7204397, Carbamimidothioic Acid 2-Aminoethyl Ester Dihydrobromide, AKOS003624181

ID: 2563

chemical graph of compound 2563



InChIKey: XDXDZDZNSLXDNA-TZNDIEGXSA-N
SMILES: C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 42890
synonyms found at PubChem are:
IDARUBICIN, 58957-92-9, 4-Demethoxydaunorubicin, Idarubicina, 4-Demethoxydaunomycin, Idarubicinum, Idarubicine, Idamycin, Idarubicin Hcl, Idarubicine [INN-French], Idarubicinum [INN-Latin], Idarubicina [INN-Spanish], Idarubicin [INN:BAN], IMI 30, IMI-30, 4-Desmethoxydaunorubicin, Daunomycin, 4-demethoxy-, UNII-ZRP63D75JW, Idarubicin (INN), Idarubicin Hcl Pfs, Zavedos (TN), Zavedos, NSC-256439, CCRIS 5083, 4-DMD, ZRP63D75JW, CHEBI:42068, 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-, Idamycin PFS, Idamycin (TN), DMDR, I 1656, (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside, DM5, MLS001401448, (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione, (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione, (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione, 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-6,9,11-trihydroxy-, (7S-cis)-, C26H27NO9, NCGC00093976-03, SMR000466355, SR-01000075934, demethoxydaunorubicin, (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, D01XDL, AC1L28SA, AC1Q6JJ4, SCHEMBL3750, CHEMBL1117, Lopac0_000600, KBioSS_002388, Idarubicin hydrochloride, solid, cid_636362, GTPL7083, DTXSID7023142, IDARUBICIN(Hydrochloride form), BDBM58490, MolPort-006-167-730, XDXDZDZNSLXDNA-TZNDIEGXSA-N, BCPP000207, HMS2089D05, HMS3261H22, ZINC3920266, Tox21_500600, AKOS015895563, AC-9384, API0002970, BCP9000773, CCG-204689, DB01177, LP00600, NCGC00093976-01, NCGC00093976-02, NCGC00093976-04, NCGC00093976-05, NCGC00261285-01, 57852-57-0 (HYDROCHLORIDE), AN-11145, CC-29462, LS-94015, SC-17016, EU-0100600, FT-0621481, D08062, Z-3092, 15158-EP2270008A1, 15158-EP2272827A1, 15158-EP2275420A1, 15158-EP2277879A1, 15158-EP2280012A2, 15158-EP2281815A1, 15158-EP2289892A1, 15158-EP2292615A1, 15158-EP2292617A1, 15158-EP2295055A2, 15158-EP2295416A2, 15158-EP2295426A1, 15158-EP2295427A1, 15158-EP2298748A2, 15158-EP2298764A1, 15158-EP2298765A1, 15158-EP2301928A1, 15158-EP2301933A1, 15158-EP2305640A2, 15158-EP2305642A2, 15158-EP2305671A1, 15158-EP2308833A2, 15158-EP2308855A1, 15158-EP2311453A1, 15158-EP2311808A1, 15158-EP2311825A1, 15158-EP2311827A1, 15158-EP2311829A1, 15158-EP2311842A2, 15158-EP2316832A1, 15158-EP2316833A1, AB00698511-06, AB00698511-08, AB00698511-09, AB00698511-10, AB00698511_11, 957I929, A832088, C-22925, I06-1097, SR-01000075934-1, BRD-K69650333-001-01-1, BRD-K69650333-001-02-9, BRD-K69650333-003-14-0, Idarubicin, United States Pharmacopeia (USP) Reference Standard, (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside, (1s,3s)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-|A-l-lyxo-hexopyranoside, (1s,3s)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-A-l-lyxo-hexopyranoside, (7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione, (7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride, (7S,9S)-9-acetyl-7-((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione, (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride, (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride, (7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione, (7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride, 4-Demethoxydaunorubicin|||IMI-30|||NSC-256439|||(7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione, 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-9-acetyl-7-((3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy)-6,9,11-trihydroxy-, (7S-cis)-

ID: 2564

chemical graph of compound 2564



InChIKey: XDXHAEQXIBQUEZ-UHFFFAOYSA-N
SMILES: CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 68727
synonyms found at PubChem are:
Ropinirole hydrochloride, 91374-20-8, Ropinirole HCl, 4-(2-(Dipropylamino)ethyl)indolin-2-one hydrochloride, ReQuip XL, Ropinirole (hydrochloride), UNII-D7ZD41RZI9, Ropinirole hydrochloride [USAN:USP], SK&F 101468-A, D7ZD41RZI9, SKF 101468 hydrochloride, SK&F-101468A, 4-(2-(Dipropylamino)ethyl)-2-indolinone monohydrochloride, 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, Requip (TN), 1,3-Dihydro-4-(2-(dipropylamino)ethyl)-2H-indol-2-one monohydrochloride, 4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one hydrochloride, 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one hydrochloride, 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one hydrochloride, 2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, monohydrochloride, SK&F-101468-A, SR-01000076215, 4-[2-(dipropylamino)ethyl]indolin-2-one hydrochloride, Adartrel, Repreve, Requi, 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one;hydrochloride, Ropinirole hydrochloride [USAN], ReQuip LP, ReQuip PR, ReQuip XR, Ropinirolhydrochloride, Ropinirole hydrochloride/, Ropinirole hydrochloride;, AC1L2ABS, AC1Q3EQJ, JZP-7, SCHEMBL40760, MLS003899234, CHEBI:8889, CHEMBL1200411, CTK8B7890, HY-B0623A, KS-00002WRZ, DTXSID50238533, NVD-434, MolPort-003-987-439, XDXHAEQXIBQUEZ-UHFFFAOYSA-N, 91374-21-9 (Parent), ACT02690, BCP02130, EBD38503, SKF-101468A, Tox21_501101, 91374-21-9 (base), ABP000199, AC-735, AC-736, ANW-58872, FC0024, MFCD01754173, NP-201, Ropinirole hydrochloride (JAN/USAN), s3189, AKOS015844988, BS-1020, CCG-213346, CS-2864, HP-3000, LP01101, MCULE-8190476072, KS-000011L6, NCGC00094373-01, NCGC00261786-01, 4CA-1107, AN-15584, BC207366, KB-80420, LS-83828, SMR001456484, 91374-20-8 (HCl), AB0009822, TC-030791, TL8005858, EU-0101101, FT-0642200, ST24042825, D00784, M-1298, R 4152, 91374-20-8,91374-21-9(freebase), 374R208, A843815, Ropinirole hydrochloride, powder, >=98% (HPLC), I06-0693, SR-01000076215-2, SR-01000076215-5, 4-(2-(Dipropylamino)ethyl)indolin-2-onehydrochloride, 4-(2-di-n-propylaminoethyl)-2(3H)indolone hydrochloride, Z1695926158, 4-(2-di-n-propylaminoethyl)-2(3H)-indolone hydrochloride, 4-[2-(Di-n-propylamino)ethyl]-2(3H)-indolone Hydrochloride, Ropinirole hydrochloride, EuropePharmacopoeia (EP) Reference Standard, 2H-Indol-2-one, 1,3-dihydro-4-(2-(dipropylamino)ethyl)-, monohydrochloride, Ropinirole for peak identification 1, EuropePharmacopoeia (EP) Reference Standard, Ropinirole for peak identification 2, EuropePharmacopoeia (EP) Reference Standard, Ropinirole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Ropinirole hydrochloride, United States Pharmacopeia (USP) Reference Standard, SKF 101468; 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, AKOS026750552

ID: 2565

chemical graph of compound 2565



InChIKey: XEAQIWGXBXCYFX-GUOLPTJISA-N
SMILES: COC1=CC(=O)O[C@H](C1)/C=C/C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281565
synonyms found at PubChem are:
Kawain, kavain, 500-64-1, (+)-Kavain, Kavain, dl-, Gonosan, L-KAWAIN, Kawaih, (R)-(+)-Kavain, UNII-W1ES06373M, CHEBI:6117, W1ES06373M, NSC 112162, EINECS 207-907-2, (R)-5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)-, 4-Methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone, 5-Hydroxy-3-methoxy-7-phenyl-2,6-heptadienoic acid gamma-lactone, 2H-PYRAN-2-ONE, 5,6-DIHYDRO-4-METHOXY-6-STYRYL-, (R)-, Kavaform (TN), CAS-500-64-1, AC1NQYMY, Prestwick2_000207, Prestwick3_000207, (R-(E))-5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one, DSSTox_CID_13595, DSSTox_RID_79087, DSSTox_GSID_33595, BSPBio_000193, MLS002154236, SCHEMBL515202, BPBio1_000213, CHEMBL578607, DTXSID5033595, CHEBI:92164, MolPort-006-069-352, XEAQIWGXBXCYFX-GUOLPTJISA-N, HMS1568J15, HMS2095J15, HMS2230N15, ZINC1703459, Tox21_200907, 8163AH, NSC112162, AKOS030631732, MCULE-6416239526, NSC-112162, NCGC00091905-01, NCGC00091905-02, NCGC00091905-03, NCGC00091905-05, NCGC00258461-01, CJ-28789, SMR001233508, AB00513818, C09947, D08096, Q-100559, BRD-K09497549-001-03-6, (R,E)-4-methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one, 2H-Pyran-2-one,6-dihydro-4-methoxy-6-styryl-, (+)-, 2H-Pyran-2-one,6-dihydro-4-methoxy-6-styryl-, (R)-, (2R)-4-methoxy-2-[(E)-styryl]-2,3-dihydropyran-6-one, UNII-5L1NI60TGB component XEAQIWGXBXCYFX-GUOLPTJISA-N, (2R)-4-methoxy-2-[(E)-2-phenylethenyl]-2,3-dihydropyran-6-one, (6R)-4-methoxy-6-[(E)-2-phenylvinyl]-5,6-dihydro-2H-pyran-2-one, 2H-Pyran-2-one,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, (R-(E))- (9CI)

ID: 2566

chemical graph of compound 2566



InChIKey: XEBWQGVWTUSTLN-UHFFFAOYSA-M
SMILES: CC(=O)O[Hg]C1=CC=CC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9905811
synonyms found at PubChem are:
Acetoxy phenylmercury, Acetoxy mercuribenzene, SCHEMBL49139, P0192, phenylmercuric acetate, phenylmercury acetate, acetoxyphenylmercury, 62-38-4, Liquiphene, Anticon, Dyanacide, Gallotox, Hostaquik, Kwiksan, Meracen, Mercuron, Mersolite, Neantina, Norforms, Nylmerate, Phenmad, Programin, Quicksan, Trigosan, Verdasan, Ziarnik, Bufen, Femma, Riogen, Scutl, Phix, mercuriphenyl acetate, phenomercuric acetate, Contra Creme, Fungicide R, Hong nien, Antimucin WDR, Fungitox OR, Sanitized SPG, Mersolite 8, Spor-Kil, (acetoxymercuri)benzene, Phenyl mercuric acetate, Phenylmercuriacetate, Puraturf 10, Quicksan 20, (acetato-O)phenylmercury, Agrosan GN 5, Metasol 30, Panomatic, Sanmicron, Shimmerex, Cekusil, Celmer, Pamisan, Seedtox, Setrete, Volpar, PMAC, PMAL, PMAS, Purasan-SC-10, Tag Fungicide, Mersolite D, Spruce Seal, Antimucin WBR, Algimycin 200, phenylmercury(II) acetate, Ceresol, Lorophyn, Mercron, Pmacetate, Ruberon, Sanitol, Samtol, Bufen 30, (Acetato)phenylmercury, Mercury, (acetato-O)phenyl-, Agrosan D, Fenylmercuriacetat, Mercury, acetoxyphenyl-, Seed Dressing R, PMA (fungicide), Intercide 60, Octan fenylrtutnaty, Hl-331, Verdasan (VAN), Zaprawa Nasienna R, Mercury, (acetato)phenyl-, Troysan 30, TAG 331, Benzene, (acetoxymercuri)-, Hexasan (fungicide), Tag HL 331, Intercide PMA 18, Benzene, (acetoxymercurio)-, Troysan PMA 30, Nuodex PMA 18, Phenylquecksilberacetat, Mergal A 25, Parasan (bactericide), Caswell No. 656, Phenylquecksilberacetate, SC-110, Mercury(II) acetate, phenyl-, Acetate phenylmercurique, Algimycin, Tag (VAN), Ceresan universal, Fenylmercuriacetat [Czech], Fenylmerkuriacetat [Czech], RCRA waste number P092, Acetic acid, phenylmercury(II) salt, Octan fenylrtutnaty [Czech], (aceto)phenylmercury, CCRIS 4858, acetoxy(phenyl)mercury, Phenylquecksilberacetat [German], HSDB 1670, Acetate phenylmercurique [French], Acetic acid, phenylmercury deriv., (acetoxymercurio)-benzene, EINECS 200-532-5, NSC 35670, UN1674, RCRA waste no. P092, Acetate de phenylmercure [ISO-French], EPA Pesticide Chemical Code 066003, Phenylmercuric acetate [NF], AI3-14668, (acetato-kappaO)(phenyl)mercury, Mercury, (acetato-kappaO)phenyl-, Phenylmercury acetate [BSI:ISO], Hexasan, fungicide, NCGC00091050-02, C.I. Pigment Green 2, DSSTox_CID_1150, WLN: 1VO-HG-R, DSSTox_RID_75977, Phenylmercuric acetate (NF), DSSTox_GSID_21150, Phenylmercury acetate [Mercury and mercury compounds], Fenylmerkuriacetat, CAS-62-38-4, Acetate de phenylmercure, C8H8HgO2, Fungitox, Unisan, Phenylmercuric Acetate [USAN], Shimmer-ex, Cosan PMA, Advacide PMA 18, Mercury, (acetato-.kappa.O)phenyl-, Phenylmercury deriv., acetato(phenyl)mercury, Nildew AC 30, Phenyl mercurie acetate, Spectrum_000724, Phenylmercury(II)Acetate, Spectrum2_000943, Spectrum3_000779, Spectrum4_000394, Spectrum5_001660, Mergal A25, NCIOpen2_007948, BSPBio_002458, KBioGR_000947, KBioSS_001204, Phenylmercuric acetate, 97%, DivK1c_000286, SPECTRUM1500644, SPBio_000906, Nuodex PMA 18, Acetic acid, phenylmercury deriv, DTXSID7021150, CHEBI:27684, HMS500O08, KBio1_000286, KBio2_001204, KBio2_003772, KBio2_006340, KBio3_001678, NINDS_000286, XEBWQGVWTUSTLN-UHFFFAOYSA-M, HMS1921O03, HMS2092E18, Pharmakon1600-01500644, NSC35670, NSC61321, Tag HL-331, Tox21_111068, Tox21_202241, Tox21_300589, 8055AF, CCG-39751, NSC-35670, NSC-61321, NSC757402, AKOS015888302, Tox21_111068_1, LS-1478, NSC-757402, IDI1_000286, NCGC00091050-01, NCGC00091050-03, NCGC00091050-04, NCGC00091050-05, NCGC00091050-06, NCGC00091050-07, NCGC00091050-09, NCGC00164424-01, NCGC00254390-01, NCGC00259790-01, CC-33706, SBI-0051573.P002, Phenylmercuric acetate [UN1674] [Poison], Phenylmercuric acetate [UN1674] [Poison], 2983-EP2301536A1, 2983-EP2301538A1, 2983-EP2311455A1, 2983-EP2316452A1, D05464, Phenylmercury acetate, purum, >=98.0% (Hg), AB00052136_02, C-34699, SR-05000001922, SR-05000001922-1, I01-10412, 112415-59-5, 1337-06-0, 61840-45-7, 64684-45-3

ID: 2567

chemical graph of compound 2567



InChIKey: XECQQDXTQRYYBH-UHFFFAOYSA-N
SMILES: CNCCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9918
synonyms found at PubChem are:
Norcyclobenzaprine, Desmethylcyclobenzaprine, UNII-T6X8KQ83F4, T6X8KQ83F4, 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-1-propanamine, XECQQDXTQRYYBH-UHFFFAOYSA-N, 303-50-4, 5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cycloheptene, Norproheptatrien, 10,11-Dehydronortriptyline, Prestwick_807, AC1Q1ITT, N-Desmethylcyclobenzaprine, Prestwick0_000513, Prestwick1_000513, Prestwick2_000513, Prestwick3_000513, AC1L1U3Z, G 38188, BSPBio_000465, MLS002153855, SPBio_002386, BPBio1_000513, SCHEMBL2240126, CHEMBL1557167, CHEBI:93101, HMS1569H07, HMS2096H07, HMS2233K21, HMS3373C08, HMS3713H07, ZINC2040609, AKOS005065415, CCG-220513, NCGC00016424-01, NCGC00016424-02, CAS-303-50-4, SMR001233213, SR-01000841257, SR-01000841257-2, BRD-K63165456-001-03-3, 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methyl-1-propanamine, 5H-Dibenzo(a,d)cycloheptene-DELTA5,gamma-propylamine, N-methyl-

ID: 2568

chemical graph of compound 2568



InChIKey: XEDCWWFPZMHXCM-UHFFFAOYSA-M
SMILES: CC[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 657306
synonyms found at PubChem are:
PIPENZOLATE BROMIDE, 125-51-9, Piptalake, Piptal, Piptil, Pipenzolate (bromide), NEPB Br, Pipenzolate methobromide, Pipenzolate methylbromide, Pipenzolate methyl bromide, JB-323, N-Ethyl-3-piperidylbenzilate methobromide, MLS000069572, 1-Ethyl-3-piperidyl benzilate methylbromide, Benzilic acid, 1-ethyl-3-piperidyl ester methylbromide, 1-Ethyl-3-hydroxy-1-methyl-piperidinium bromide benzilate, NCGC00094991-01, SMR000058823, Benzilic acid, ester with 1-ethyl-3-hydroxy-1-methylpiperidinium bromide, DSSTox_CID_3480, DSSTox_RID_77046, DSSTox_GSID_23480, QPB, Pipenzolato bromuro, Pipenzolati bromidum, Bromure de pipenzolate, Bromuro de pipenzolato, SR-01000003111, PIPENZOLONE BROMIDE, C22H28NO3.Br, Piptal, tablet, (1-ethyl-1-methylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide, Prestwick_159, BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE, AC1LCWBS, Opera_ID_154, Pipenzolatemethyl bromide, CAS-125-51-9, Pipenzolate bromide (INN), MLS001148441, MLS002222177, SCHEMBL249587, SPECTRUM1503053, CHEMBL1401367, DTXSID2023480, Piperidinium, bromide, benzilate, REGID_for_CID_657306, CTK8G2437, HMS501P20, HY-B0953A, NSC4347, MolPort-003-666-432, HMS1570G22, HMS1922A21, HMS2097G22, HMS2232D11, HMS3370K12, HMS3714G22, Pharmakon1600-01503053, 13473-38-6 (Parent), NSC-4347, Tox21_111378, 2658AH, CCG-39184, JB 323, NSC758221, AKOS022180522, Tox21_111378_1, API0003871, NSC-758221, NCGC00018203-06, NCGC00094991-02, NCGC00094991-03, NCGC00094991-04, FT-0715349, D07084, C-54956, WLN: T6KTJ A2 A1 COVXQR & R & Q & E, SR-01000003111-3, SR-01000003111-4, 1-ethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-methylpiperidinium bromide, 1-ethyl-3-{[hydroxy(diphenyl)acetyl]oxy}-1-methylpiperidinium bromide, 1-Ethyl-3-hydroxy-1-methyl-piperidinium bromide, benzilic acid ester, (1-ethyl-1-methylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate bromide, Piperidinium, 1-ethyl-3-((hydroxydiphenylacetyl)oxy)-1-methyl-, bromide (9CI)

ID: 2569

chemical graph of compound 2569



InChIKey: XEGGRYVFLWGFHI-UHFFFAOYSA-N
SMILES: CC1(OC2=C(O1)C(=CC=C2)OC(=O)NC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2314
synonyms found at PubChem are:
bendiocarb, Bencarbate, 22781-23-3, Ficam, Ficam W, Multamat, Dycarb, Garvox, Niomil, Turcam, Bendiocarbamate, Multimet, Rotate, Tattoo, Tatoo, Seedox 80W, Ficam 80W, Ficam D, Ficam ULV, Fisons NC 6897, Bendiocarbe, Ficam B, Ficam ulv' ul, Ficam Z, 2,2-Dimethyl-1,3-benzodioxol-4-ol methylcarbamate, 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, methylcarbamate, UNII-QFH0ZU0A5U, Bendiocarbe [ISO-French], OMS-1394, Bendiocarb [ANSI:BSI:ISO], CCRIS 9062, 2,2-Dimethyl-1,3-benzodioxol-4-yl methylcarbamate, CHEBI:34556, HSDB 3918, 2,3-Isopropylidene-dioxyphenyl methylcarbamate, Methylcarbamic acid 2,3-(isopropylidenedioxy)phenyl ester, EINECS 245-216-8, NC6897, QFH0ZU0A5U, RCRA waste no. U278, EPA Pesticide Chemical Code 105201, NC 6897, 2,2-Dimethylbenzo-1,3-dioxol-4-yl methylcarbamate, BRN 1315404, 2,2-Dimethyl-1,3-benzdioxol-4-yl N-methylcarbamate, (2,2-dimethyl-1,3-benzodioxol-4-yl) N-methylcarbamate, 1,3-Benzodioxole, 2,2-dimethyl-4-(N-methylcarbamato)-, AI3-27695, 1,3-Benzodioxole, 2,2-dimethyl-4-(N-methylaminocarboxylato)-, Carbamic acid, methyl-, 2,3-(isopropylidenedioxy)phenyl ester, Carbamic acid, methyl-, 2,3-(dimethylmethylenedioxy)phenyl ester, XEGGRYVFLWGFHI-UHFFFAOYSA-N, 2,2-Dimethyl-1,3-benzodioxole-N-methylcarbamate, 2,2-Dimethyl-1,3-benzodioxol-4-yl N-methylcarbamate, 1,3-Benzodioxol-4-ol, 2,2-dimethyl-, methyl carbamate, 2,3-Isopropylidenedioxyphenyl methylcarbamate, DSSTox_CID_12327, DSSTox_RID_78914, DSSTox_GSID_32327, 2,2-dimethyl-4-(methylcarbamoyloxy)-1,3-benzodioxole, Seedoxin, Sedox, CAS-22781-23-3, Fuam, Garvox 3G, Ficam 80 W, Spectrum_001917, SpecPlus_000548, Ficam plus (Salt/Mix), AC1L1DEF, Spectrum2_001726, Spectrum3_000854, Spectrum4_000694, Spectrum5_002026, SCHEMBL22080, BSPBio_002467, KBioGR_001187, KBioSS_002459, SPECTRUM330063, 2,2-dimethyl-1,3-benzodioxol-4-yl-methylcarbamat, MLS002695990, DivK1c_006644, SPBio_001772, AC1Q61J7, CHEMBL465018, DTXSID9032327, KBio1_001588, KBio2_002452, KBio2_005020, KBio2_007588, KBio3_001967, XEGGRYVFLWGFHI-UHFFFAOYSA-, HMS3087C14, ZINC2015426, Tox21_201562, Tox21_300777, BDBM50064618, CCG-39499, Bendiocarb 10 microg/mL in Isooctane, AKOS015888418, ACM22781233, NCGC00094543-01, NCGC00094543-02, NCGC00094543-03, NCGC00094543-04, NCGC00094543-05, NCGC00094543-06, NCGC00094543-07, NCGC00254681-01, NCGC00259111-01, AN-17943, Bendiocarb 100 microg/mL in Acetonitrile, CJ-31264, LS-50160, SMR000777869, FT-0602885, X6232, Bendiocarb, PESTANAL(R), analytical standard, 2,3-(Isopropylidenedioxy)phenol Methylcarbamate, C14433, 781B233, J-014852, 2,2-Dimethyl-1,3-benzodioxol-4-yl methylcarbamate #, 2,2-dimethylbenzo[d][1,3]dioxol-4-yl methylcarbamate, I01-10264, InChI=1/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13)

ID: 2570

chemical graph of compound 2570



InChIKey: XEYBRNLFEZDVAW-ARSRFYASSA-N
SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5280360
synonyms found at PubChem are:
Prostaglandin E2, Dinoprostone, PGE2, 363-24-6, Prostin E2, Prepidil, Cervidil, Propess, Minprositin E2, Minprostin E2, Dinoproston, Prostin, Prostarmon E, Dinoprostonum, (15S)-Prostaglandin E2, l-Prostaglandin E2, Dinoprostona, PGE2alpha, l-PGE2, Prostaglandin E2alpha, Prepidil Gel, PGE2 alpha, Dinoprostonum [INN-Latin], Dinoprostona [INN-Spanish], U-12062, Prostaglandin E2 alpha, Prostaglandin E, Prostin E, Prostarmon E2, UNII-K7Q1JQR04M, Cervidil (TN), Prepidil (TN), (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, NSC 165560, [3H]PGE2, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid, U 12062, Prostin E2 (TN), [3H]prostaglandin E2, Dinoprostone [USAN:INN:BAN:JAN], EINECS 206-656-6, CHEMBL548, NSC 196514, K7Q1JQR04M, 7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid, l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid, Dinoprostone Prostaglandin E2, Dinoprostone (JAN/USP/INN), (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid, BML1-F07, CHEBI:15551, XEYBRNLFEZDVAW-ARSRFYASSA-N, (5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, l-, Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11alpha,13E,15S)-, Prostaglandin E(2), BMS-279654 & PGE2, Dinoprostone beta-Cyclodextrin Clathrate, NCGC00092361-05, (-)-Prostaglandin E2, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, Prostaglandin E2.alpha., (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate, (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic, (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, DSSTox_CID_2947, 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, DSSTox_RID_76801, DSSTox_GSID_22947, (Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid, (Z)-7-[(1r,2r,3r)-3-Hydroxy-2-[(E,3s)-3-Hydroxyoct-1-Enyl]-5-Oxo-Cyclopentyl]hept-5-Enoic Acid, 9-oxo-11R,15S-dihydroxy-5Z,13E-prostadienoic acid, Cerviprime, Prostenone, Enzaprost E, (5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid, 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid, Gel, Prepidil, Prosta-5,13-dien-1-oic acid, (5Z,11-alpha,13E,15S)-11,15-dihydroxy-9-oxo-, E2, Prostaglandin, CAS-363-24-6, Prostaglandin,PGE2, alpha, PGE2, U,062, E2alpha, Prostaglandin, SR-05000001459, alpha, Prostaglandin E2, E2 alpha, Prostaglandin, primiprost, (5Z,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, Prosta-5, (5Z,11.alpha.,13E,15S)-11,15-dihydroxy-9-oxo-, Prosta-5, 11,15-dihydroxy-9-oxo-, (5Z,11.alpha.,13E,15S)-, Prosta-5, 11,5-dihydroxy-9-oxo-, (5Z,11.alpha.,13E,15S)-, [3H]dinoprostone, 5-Heptenoic acid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-, prosta-glandin e2, NCGC00092361-06, (E,2R,3R)-7-[3-hydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]-5-oxocyclopentyl]-5-heptenoic acid, Prestwick_793, Propess (TN), [3H]prostin E2, AC1NQWXW, Dinoprostone [USAN:USP:INN:BAN:JAN], D06FEA, SCHEMBL25533, BSPBio_001490, GTPL1883, GTPL1916, (5Z,11|A,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid, DTXSID4022947, [3H]-PGE2, BDBM35847, MolPort-003-939-184, HMS1361K12, HMS1791K12, HMS1989K12, HMS2089D17, HMS3268J12, HMS3402K12, HMS3648F07, EX-A1773, ZINC3830713, Tox21_111196, LMFA03010003, MFCD00077861, NSC165560, NSC196514, AKOS015920228, Tox21_111196_1, AC-6098, CCG-208092, CCG-208256, CS-6932, DB00917, NSC-165560, NSC-196514, RP17686, IDI1_033960, SMP2_000056, NCGC00092361-01, NCGC00092361-02, NCGC00092361-03, NCGC00092361-04, AJ-45765, AN-10387, BC219642, BR-72815, HY-101952, LS-125823, B7005, P1884, 1798-EP2272832A1, 1798-EP2277848A1, 1798-EP2277858A1, 1798-EP2295055A2, 1798-EP2298767A1, 1798-EP2301922A1, 1798-EP2305641A1, 1798-EP2305653A1, 1798-EP2308510A1, 1798-EP2308872A1, 1798-EP2311453A1, 1798-EP2311808A1, 1798-EP2311829A1, 1798-EP2314574A1, 1798-EP2314587A1, 1798-EP2316829A1, C00584, D00079, Prostaglandin E2, >=93% (HPLC), synthetic, 363P246, SR-01000946417, J-502620, SR-01000946417-1, SR-05000001459-1, SR-05000001459-3, SR-05000001459-4, U-12,062, BRD-K26521938-001-04-9, 05D31BD5-818B-4A92-8CFC-BEC19926A5B3, Dinoprostone, European Pharmacopoeia (EP) Reference Standard, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoic acid, (5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate, Dinoprostone, United States Pharmacopeia (USP) Reference Standard, (5Z,11?,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1oic acid, (5Z,11I+/-,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid, (5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoic acid, Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture, 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)- (8CI), 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-(8CI), Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11.alpha.,13E,15S)-, Prostaglandin E2, gamma-irradiated, powder, BioXtra, suitable for cell culture, P2E

ID: 2571

chemical graph of compound 2571



InChIKey: XFHBFOSBGWDTRO-KZYPOYLOSA-M
SMILES: C[C@H]1OC[C@H](O1)C[N+](C)(C)C.[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 657346
synonyms found at PubChem are:
(+)-cis-Dioxolane iodide, (+)-CIS-DIOXOLANE, MLS000069362, 16709-43-6, SMR000058762, AC1LCWE4, Opera_ID_1651, CHEMBL387632, REGID_for_CID_657346, SCHEMBL16447039, (3H)-CD, DTXSID40349682, HMS2234J11, NCGC00093796-01, C-008, EU-0100361, (Methyl(trimethylammonio)methyl)-1,3-dioxolane, SR-01000075309, J-500051, SR-01000075309-1, L(+)-cis-2-Methyl-4-trimethylammoniummethyl-1,3-dioxolane iodide, 1,3-Dioxolane-4-methanaminium, N,N,N,2-tetramethyl-, iodide, (2S-cis)-, trimethyl-[[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]methyl]azanium iodide

ID: 2572

chemical graph of compound 2572



InChIKey: XFRAZGWQOHTYEX-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=NN=C(N=N2)C3=CC=C(C=C3)C

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 576074
synonyms found at PubChem are:
1,2,4,5-Tetrazine, 3,6-bis(4-methylphenyl)-, 51973-26-3, 3,6-Bis(4-methylphenyl)-tetrazine, AC1LB47N, CHEMBL17783, CTK1G3683, DTXSID50341834, MolPort-019-738-045, XFRAZGWQOHTYEX-UHFFFAOYSA-N, ZINC32137519, 3,6-Bis(p-tolyl)-1,2,4,5-tetrazine, 3,6-bis(4-methylphenyl)-1,2,4,5-tetrazine, 3,6-Bis(4-methylphenyl)-1,2,4,5-tetraazine #

ID: 2573

chemical graph of compound 2573



InChIKey: XFRXWLWUUDJHPB-UHFFFAOYSA-N
SMILES: C1CC1C2=CC=CC=C2OCC3=NCCN3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957512
synonyms found at PubChem are:
Cirazoline hydrochloride, 40600-13-3, 2-((2-Cyclopropylphenoxy)methyl)-4,5-dihydro-1H-imidazolium chloride, 2-[(2-Cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole hydrochloride, SR-01000075264, Cirazoline HCl, 2-((2-cyclopropylphenoxy)methyl)-4,5-dihydro-1H-imidazole hydrochloride, EINECS 254-995-3, EU-0100354, MLS002153214, SCHEMBL466850, Cirazoline hydrochloride, solid, CHEMBL1255646, CTK8F8670, AOB5903, DTXSID70193610, MolPort-003-940-674, 59939-16-1 (Parent), Tox21_500354, AKOS022488639, API0008375, CCG-221658, LP00354, NCGC00093790-01, NCGC00261039-01, SMR001230692, B6490, C-223, FT-0696611, SR-01000075264-1, SR-01000075264-3, 2-(2-CYCLOPROPYLPHENOXYMETHYL)IMIDAZOLINE HYDROCHLORIDE, 1H-Imidazole,2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-,hydrochloride(1:1)

ID: 2574

chemical graph of compound 2574



InChIKey: XFZJGFIKQCCLGK-UHFFFAOYSA-M
SMILES: C[N+]1(CCN(CC1)C2=CC=CC=C2)C.[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5911
synonyms found at PubChem are:
1,1-Dimethyl-4-phenylpiperazinium iodide, 54-77-3, DMPP, DMPP iodide, 1,1-dimethyl-4-phenylpiperazin-1-ium iodide, Dimethylphenylpiperazinium iodide, 1,1-Dimethyl-4-phenylpiperazine iodide, N,N-Dimethyl-N'-phenylpiperazinium iodide, Dimethyl-4-phenylpiperazium iodide, 1,1-Dimethyl-4-phenyl-piperazinium iodide, UNII-X95H7DRX99, EINECS 200-213-0, NSC 89754, CHEMBL47814, MLS000069397, CHEBI:4290, X95H7DRX99, PIPERAZINIUM, 1,1-DIMETHYL-4-PHENYL-, IODIDE, SMR000058572, C12H19N2.I, ACMC-1AUNK, AC1L1LEI, Opera_ID_1764, MLS001424200, SCHEMBL305083, CTK5A2549, MolPort-003-932-290, HMS2051F22, HMS2234H18, HMS3261O21, HMS3370L09, HMS3393F22, NSC89754, Tox21_500400, 6008AF, ANW-32189, NSC-89754, AKOS015833271, CCG-101065, FCH1601168, LP00400, LS41910, MCULE-2582183268, NC00315, TRA0171112, KS-000012Q8, 1,1-dimethyl-4-phenylpiperazine, iodide, 1,1-Dimethyl-4-phenylpiperaziniumIodide, NCGC00093827-01, NCGC00261085-01, AK140648, CPD000058572, KB-64162, SAM001246914, Piperazinium,1-dimethyl-4-phenyl-, iodide, WLN: T6K DNTJ A1 A1 DR &Q &I, 1-Methyl-4-phenylpiperazinium 1-Methiodide, AX8052430, LS-113719, TR-031028, D1343, EU-0100400, FT-0714534, ST24036608, ST50994546, C07488, D 5891, C-45761, I13-600, SR-01000002980, SR-01000002980-2, Piperazinium,1,1-dimethyl-4-phenyl-, iodide (1:1), 1,1-Dimethyl-4-phenylpiperazinium iodide, >=99.0% (AT), 1,1-Dimethyl-4-phenylpiperazinium iodide, >=98% (TLC or titration), powder

ID: 2575

chemical graph of compound 2575



InChIKey: XFZJWBFZLNLKNR-UHFFFAOYSA-M
SMILES: COC1=C(C=CC(=C1)C(CO)O)OS(=O)(=O)[O-].[K+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957568
synonyms found at PubChem are:
MHPG sulfate potassium, 71324-20-4, MHPG sulfate potassium salt, (3-Methoxy-4-sulfonyloxyphenyl)glycol potassium salt, MOPEG sulfate potassium salt, 4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt, MLS002153355, CHEMBL1256624, HMS2234O18, HMS3261N14, HMS3371O01, Tox21_500626, MFCD00043417, AKOS027383244, LP00626, NCGC00016154-02, NCGC00093995-01, NCGC00261311-01, SMR000326852, EU-0100626, FT-0641345, H 8759, 4-Hydroxy-3-methoxyphenylglycol-4-sulfate potassium, POTASSIUM 4-(1,2-DIHYDROXYETHYL)-2-METHOXYPHENYL SULFATE, 4-HYDROXY-3-METHOXY-D3-PHENYLETHYLENE GLYCOL 4-SULPHATE POTASSIUM SALT, 4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt, >=98% (HPLC), powder

ID: 2576

chemical graph of compound 2576



InChIKey: XGDFITZJGKUSDK-UDYGKFQRSA-N
SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957481
synonyms found at PubChem are:
Bestatin hydrochloride, 65391-42-6, Bestatin (hydrochloride), N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride, SR-01000075724, NCGC00093685-01, BESTATIN HCL, Bestatin monohydrochloride, C16H24N2O4.HCl, BIMI2137, CHEMBL538595, SCHEMBL3880484, HY-B0134A, MolPort-004-964-160, ZX-AFC000603, Tox21_500214, MFCD00058004, AKOS030526173, API0001675, CCG-207863, CS-1911, LP00214, Bestatin hydrochloride, >=98% (HPLC), NCGC00260899-01, AB0020587, B4000, EU-0100214, FT-0622881, V1527, B 8385, M01391, C-46075, SR-01000075724-1, SR-01000075724-2, SR-01000075724-6, (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoic acid hydrochloride, Bestatin, [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine hydrochloride

ID: 2577

chemical graph of compound 2577



InChIKey: XGEYXJDOVMEJNG-HTFDPZBKSA-N
SMILES: C1=CC(=C(C=C1/C=C/C(=O)C2=C(C(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6441269
synonyms found at PubChem are:
Marein, 535-96-6, Okanin-4'-O-glucoside, CHEMBL490510, EINECS 208-623-1, SCHEMBL620953, AC1O5V02, MolPort-006-111-677, ZX-AFC002766, BDBM50250286, ZINC13827660, CCG-208403, NCGC00163591-01, J3.585.377D, SR-05000002270, SR-05000002270-2, (E)-1-(2,3-dihydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one, (E)-3-(3,4-Dihydroxyphenyl)-1-(4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl)-2-propen-1-one, (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one, 1-[4-(beta-D-Glucopyranosyloxy)-2,3-dihydroxyphenyl]-3-(3,4-dihydroxyphenyl)-2-propene-1-one, 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl)-, (E)-

ID: 2578

chemical graph of compound 2578



InChIKey: XGPBRZDOJDLKOT-NXIDYTHLSA-N
SMILES: C/C=C(/C)\C(=O)O[C@H]1[C@H](C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"TH Ma" "H Yang" "WL Na" "SG Hou" "LN Xu" "X Liu" "S Lin"


CID is 38347607
synonyms found at PubChem are:
Praeruptorin A, 73069-27-9, (+)-Praeruptorin A, 73069-25-7, (-)-Praeruptorin A, PraeruptorinA, CHEMBL2376509, DTXSID20653395, MolPort-020-005-726, ZINC31156206, AKOS016011014, AJ-84194, AK119810, AX8245226, (9S,10S)-10-(Acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl (2Z)-2-methylbut-2-enoate, [(9S,10S)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate

ID: 2579

chemical graph of compound 2579



InChIKey: XGWATTXMMMANFJ-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC(C)(C)C=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3519541
synonyms found at PubChem are:
CGP-13501, Cgp 13501, 56189-68-5, XGWATTXMMMANFJ-UHFFFAOYSA-N, CGP13501, 3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal, SR-01000075739, Tocris-1514, AC1MRKO6, Lopac-C-0987, D06VMV, Lopac0_000179, MLS002153400, GTPL7848, SCHEMBL2372640, CHEMBL1256746, CHEBI:93680, MolPort-003-940-612, HMS2236G06, HMS3260D19, HMS3268A11, HMS3369F19, ZINC2526561, Tox21_500179, BN0130, CPG-37656, AKOS024456642, API0007844, CCG-204274, LP00179, NCGC00015211-01, NCGC00015211-02, NCGC00015211-03, NCGC00015211-04, NCGC00015211-05, NCGC00025199-01, NCGC00025199-02, NCGC00025199-03, NCGC00260864-01, SMR001230779, EU-0100179, CGP-13501, >=98% (HPLC), solid, C 0987, Allosteric GABA B receptor modulators, Novartis, SR-01000075739-1, SR-01000075739-3, BRD-K95851186-001-02-9, 2,2-di-methyl-3-(3,5-di-t-butyl-4-hydroxyphenyl)propanal, 3-(3,5-di-t-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal, 2,2-dimethyl-3-(3,5-di-tert.butyl-4-hydroxyphenyl) propionaldehyde, 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-?,?-dimethylbenzenepropanal, 3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanal, 3-(3,5-di-tert.butyl-4-hydroxyphenyl)-2,2-dimethylpropionaldehyde, 3-(3 inverted exclamation marka,5 inverted exclamation marka-Di-tert-butyl-4 inverted exclamation marka-hydroxy)phenyl-2,2-dimethylpropanal

ID: 2580

chemical graph of compound 2580



InChIKey: XGWFJBFNAQHLEF-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=C3C=CC=CC3=C2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2201
synonyms found at PubChem are:
anthracene-9-carboxylic acid, 9-Anthracenecarboxylic acid, 723-62-6, 9-Anthroic acid, ANCA, 9-Carboxyanthracene, 9-AC, Anthracene-10-carboxylic acid, 9-anthracene carboxylic acid, EINECS 211-964-9, NSC 151909, CHEBI:34507, XGWFJBFNAQHLEF-UHFFFAOYSA-N, A9C, Spectrum_001457, Tocris-0963, AC1Q5UNT, Spectrum3_001767, Spectrum4_000875, Spectrum5_001807, ACMC-1BFF5, D0O6KR, Anthracene-9-carboxylicacid, AC1L1D5F, AC1Q72NX, DSSTox_CID_29387, DSSTox_RID_83502, DSSTox_GSID_49427, BSPBio_003233, KBioGR_001569, KBioSS_001937, DivK1c_000919, SCHEMBL122832, SPECTRUM1502068, GTPL4113, CHEMBL1513985, DTXSID7049427, HMS502N21, KBio1_000919, KBio2_001937, KBio2_004505, KBio2_007073, KBio3_002733, KS-00000VFI, XGWFJBFNAQHLEF-UHFFFAOYSA-, MolPort-000-929-121, NINDS_000919, 9-Anthracenecarboxylic acid, 99%, HMS3267I09, ZINC391311, ACT12061, Tox21_202942, (9-AC), ANW-36194, KM1476, MFCD00001257, NSC151909, SBB067053, 16336-69-9 (hydrochloride salt), AKOS000120482, AC-4957, ACN-050877, MCULE-3056170168, NSC-151909, RL04760, RTR-031416, TRA0013851, IDI1_000919, UPCMLD0ENAT5641092:001, NCGC00024906-01, NCGC00024906-02, NCGC00024906-03, NCGC00260488-01, AJ-21084, AN-11433, AS-14182, BC201260, CAS-723-62-6, K229, KB-74703, LS-20729, SC-17379, Am J Physiol 262: C803 (1992), DB-022490, ST2419100, TL8005060, TR-031416, A0690, B6525, FT-0621618, FT-0621619, ST45028106, C13699, 723A626, SR-01000597483, I14-0844, SR-01000597483-1, W-104491, 9-Anthracenecarboxylic acid, purum, for fluorescence, >=96.0% (T), 9-Anthracenecarboxylic acid, puriss. p.a., matrix substance for MALDI-MS, >=99.0% (HPLC), InChI=1/C15H10O2/c16-15(17)14-12-7-3-1-5-10(12)9-11-6-2-4-8-13(11)14/h1-9H,(H,16,17)

ID: 2581

chemical graph of compound 2581



InChIKey: XHBZOAYMBBUURD-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)CC(=O)C2=C(C=C(C=C2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 259632
synonyms found at PubChem are:
ONONETIN, 487-49-0, 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone, NSC89759, 2',4'-dihydroxy-2-(4-methoxyphenyl)acetophenone, NSC 89759, MLS000736891, CHEMBL241858, Acetophenone, 2',4'-dihydroxy-2-(p-methoxyphenyl)-, 2,4-dihydroxy-4'-methoxydeoxybenzoin, EN300-37037, 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethan-1-one, SR-01000395029, Spectrum_000796, AC1Q4CDW, AC1Q5EDM, Spectrum2_000808, Spectrum3_001777, Spectrum4_001479, Spectrum5_000157, AC1L61HY, Oprea1_716474, BSPBio_001797, BSPBio_003273, KBioGR_002057, KBioSS_001276, SPECTRUM212097, UNII-4S084Z7YS4, SPBio_000675, SCHEMBL2948430, CTK4J0977, KBio2_001276, KBio2_003844, KBio2_006412, KBio3_002774, DTXSID50197590, MolPort-000-424-535, XHBZOAYMBBUURD-UHFFFAOYSA-N, 4S084Z7YS4, HMS2270L16, ZINC163657, ALBB-017538, KS-000017WN, ZX-AN016225, ZX-AT027613, 4213AE, BDBM50295962, CCG-38393, IN2191, NSC-89759, SBB081000, STK856460, AKOS000275879, 2,4-dihydroxy-4''-methoxydeoxybenzoin, 2,4-Dihydroxy-4/'-methoxydeoxybenzoin, MCULE-4823998554, SDCCGMLS-0066960.P001, NCGC00095540-01, NCGC00095540-02, NCGC00095540-03, AK176319, BC600829, SC-82951, SMR000528412, 2,4-Dihydroxyphenyl 4-Methoxybenzyl Ketone, KB-146357, KB-212627, LS-185348, B5811, D4816, ST50039223, A-8272, SR-01000395029-1, SR-01000395029-3, 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanon, BRD-K85385671-001-02-2, Ethanone,1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-, F0900-1857, 1-(2,4-dihydroxy-phenyl)-2-(4-methoxy-phenyl)-ethanone, Ethanone, 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-

ID: 2582

chemical graph of compound 2582



InChIKey: XHEFDIBZLJXQHF-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281614
synonyms found at PubChem are:
Fisetin, 528-48-3, 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one, 5-Desoxyquercetin, Cotinin, Fustel, Viset, 3,3',4',7-Tetrahydroxyflavone, Fisetholz, Superfustel, Fietin, Fustet, Junger fustik, Ventin sumach, Young fustic, Zante fustic, Superfustel K, 3,7,3',4'-Tetrahydroxyflavone, Ungarisches gelbholz, C.I. Natural Brown 1, Young fustic crystals, Bois bleu de Honqrie, BOIS bleude honqrie, C.I. 75620, NSC 407010, NSC 656275, 5-Deoxyquercetin, 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one, Natural Brown 1, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-, UNII-OO2ABO9578, BRN 0292829, CCRIS 9034, EINECS 208-434-4, NSC407010, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one, 7,3',4'-Trihydroxyflavonol, CHEMBL31574, OO2ABO9578, FLAVONE, 3,3',4',7-TETRAHYDROXY-, CHEBI:42567, XHEFDIBZLJXQHF-UHFFFAOYSA-N, TNP00284, NSC656275, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one, NSC-407010, Q-100599, FSE, SR-05000002249, Fiestin, Fisetine, Fisetin (Fustel), Fisetin, 15, AC1NQYQG, Spectrum_001196, 1xo2, SpecPlus_000460, Spectrum2_001160, Spectrum3_001536, Spectrum4_001070, Spectrum5_001797, D0HH8I, D0MF5Y, NCIMech_000006, SCHEMBL39454, 3,3'4'7-tetOH-Flavone, 3,4',7-Tetrahydroxyflavone, BSPBio_002952, KBioGR_001400, KBioSS_001676, 5-18-05-00291 (Beilstein Handbook Reference), MLS006011782, 528-48-3 (anhydrous), BIDD:ER0141, DivK1c_006556, SPECTRUM1502247, SPBio_001119, BDBM7457, GTPL5182, DTXSID4022317, CTK8B4476, KBio1_001500, KBio2_001676, KBio2_004244, KBio2_006812, KBio3_002452, KS-00000YFR, ZINC39111, BIF1001, Flavone,3',4',7-tetrahydroxy-, MolPort-000-882-130, ZX-AFC002753, HMS3604H03, HMS3655L22, ACT02610, HY-N0182, TNP00004, 3,3',4',7-Tetra-hydroxy-flavone, ANW-45197, BBL027612, CCG-35267, CF0050, IN2102, LMPK12111566, MFCD00006829, MFCD04220857, s2298, SBB066118, STL146392, AKOS000277885, CS-7840, DB07795, MCULE-8216354240, NSC-656275, RTR-036986, SDCCGMLS-0066657.P001, 3,2',4',7-TETRAHYDROXYFLAVONE, NCGC00017344-01, NCGC00017344-02, NCGC00017344-03, NCGC00017344-04, NCGC00017344-05, NCGC00017344-06, NCGC00095663-01, NCGC00095663-02, NCGC00178374-01, ACM345909344, AJ-08826, AK-88492, AN-45587, AS-15520, CC-28430, CI-75620, LS-69038, NCI60_003865, P707, SC-16989, SMR001835029, ST057233, ZB001095, AX8006342, Cotinin (not to be confused with Cotinine), KB-221424, ST2403855, TL8003475, FT-0613996, N2487, 28F483, C10041, S00056, C-34894, I06-0438, J-019667, SR-05000002249-2, SR-05000002249-3, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromone;dihydrate, 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-3,7-dihydroxy-, 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one #, 3,7-Dihydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one, Fisetin; 5-Deoxyquercetin; 3,3?,4?,7-Tetra??hydroxy??flavone; Natural Brown 1, InChI=1/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20

ID: 2583

chemical graph of compound 2583



InChIKey: XHQYBDSXTDXSHY-UHFFFAOYSA-N
SMILES: C(=O)(N)NN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11236
synonyms found at PubChem are:
SEMICARBAZIDE HYDROCHLORIDE, 563-41-7, Aminourea hydrochloride, Semicarbazide HCl, hydrazinecarboxamide hydrochloride, Semicarbazide chloride, Amidourea hydrochloride, Hydrazinecarboxamide, monohydrochloride, Carbamylhydrazine hydrochloride, Semicarbazide monohydrochloride, Hydrazinecarboxamide, hydrochloride, Hydrazinecarboxamide monohydrochloride, EK 226, CCRIS 556, Semicarbazide, monohydrochloride, UNII-34854VG84B, Carbamyl hydrazine.HCl, HSDB 5197, Semicarbazide hydrochloride (VAN), NSC 4732, EINECS 209-247-0, Semicarbazide, hydrochloride, Hydrazinecarboxamide, hydrochloride (VAN), AI3-52680, CHEBI:82532, Hydrazine carboxamide hydrochloride, 34854VG84B, Hydrazinecarboxamide, hydrochloride (1:1), Semikarbazide hydrochloride, aminourea;hydrochloride, SCA-HCl, semicarbazide HCl salt, PubChem15701, CH6ClN3O, NH2NHCONH2.HCl, semicarbazide hydrocloride, DSSTox_CID_244, semicarbazide-hydrochloride, semicarbazide.hydrochloride, ACMC-1B0NX, WLN: ZVMZ &GH, Aminourea hydro<->chloride, semi-carbazide hydrochloride, AC1L1WX1, SCHEMBL6932, DSSTox_RID_75458, DSSTox_GSID_20244, KSC490O3N, MLS002153236, 57-56-7 (Parent), hydrochloric acid semicarbazide, CHEMBL1256355, DTXSID4020244, CTK3J0736, NSC4732, hydrazinecarbox-amide hydrochloride, MolPort-001-757-400, XHQYBDSXTDXSHY-UHFFFAOYSA-N, KS-00000H1W, NSC-4732, Semicarbazide hydrochloride, >=99%, Tox21_200950, Tox21_501096, ANW-32488, EBD568260, MFCD00013009, AKOS015848282, CCG-222400, CS-W018530, LP01096, LS-1382, MCULE-3392559370, MP-2143, RP19032, RTC-064162, TRA0005872, NCGC00091589-01, NCGC00094369-01, NCGC00258503-01, NCGC00261781-01, AN-23700, CAS-563-41-7, KB-60429, SC-16469, SC-47308, SMR000326716, AB0010803, Semicarbazide hydrochloride, p.a., 99.0%, ST2413115, TC-064162, EU-0101096, FT-0632395, S0032, C19521, S 2201, SR-01000075648, SR-01000075648-2, F1908-0069, Semicarbazide hydrochloride, purum p.a., >=98.0% (AT), Semicarbazide hydrochloride, SAJ special grade, >=99.0%, Semicarbazide hydrochloride, VETRANAL(TM), analytical standard, SBB060865, AKOS024390901, ST51046962, aminourea; hydron; chloride, 1-azanylurea; hydron; chloride, AKOS015914967, A831007, I14-7527

ID: 2584

chemical graph of compound 2584



InChIKey: XIEGSJAEZIGKSA-UHFFFAOYSA-N
SMILES: CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9818540
synonyms found at PubChem are:
Tropisetron hydrochloride, 3-Tropanyl-indole-3-carboxylate hydrochloride, Tropisetron monohydrochloride, 105826-92-4, Navoban, J-500370, (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1H-indole-3-carboxylate hydrochloride, SDZ-ICS 930, 3-Tropanylindole-3-carboxylate hydrochloride, MLS001148140, CHEMBL554182, SCHEMBL6273985, (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride, (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-Indole-3-carboxylate Hydrochloride, MolPort-003-959-655, Pharmakon1600-01502344, 1H-Indole-3-carboxylic Acid (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride, 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, monohydrochloride, endo-, BCP07756, Tox21_501253, AC-789, BG0428, CT0261, NSC759842, AKOS015951162, API0007089, CCG-213827, ICS-205,930; Navoban; Tropisetron, LP01253, MCULE-1494492129, NSC-759842, NCGC00094493-01, NCGC00261938-01, AN-12144, KB-81357, LS-82733, SMR000653456, AB1008577, RT-016148, EU-0101253, FT-0630963, T-104, I10-18, A801326, SR-01000075588, SR-01000075588-1, Tropisetron monohydrochloride, solid, >=98% (HPLC), Tropisetron hydrochloride, European Pharmacopoeia (EP) Reference Standard, 1H-indole-3-carboxylic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride, 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride; 3-Tropanylindole-3-carboxylate monohydrochloride, AKOS026750049

ID: 2585

chemical graph of compound 2585



InChIKey: XIGAHNVCEFUYOV-BTJKTKAUSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957721
synonyms found at PubChem are:
WAY-100635 maleate salt, WAY-100635 maleate, 634908-75-1, 1092679-51-0, WAY-100635 (maleate salt), WAY 100635 maleate, WAY100635 Maleate Salt, N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide maleate, N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt, WAY100635, EU-0101229, MLS001334042, SCHEMBL4077972, CHEMBL1256924, AOB6812, DTXSID60474703, QCR-206, MolPort-003-959-939, C29H38N4O6, HMS2233G03, HMS3263F20, Tox21_501229, WAY-100635 maleate salt, powder, MFCD01321056, AKOS024458129, CCG-222533, CS-0417, LP01229, NCGC00094471-01, NCGC00261914-01, BC600353, HY-13105, KB-81481, SC-52883, SMR000875313, AB0007986, S2663, W-108, Y0235, W-5261, SR-01000075568, SR-01000075568-1, N-[2-[4-(2-, N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2, Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide maleate

ID: 2586

chemical graph of compound 2586



InChIKey: XIROXSOOOAZHLL-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C(=C(C=C1)O)O)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 10706
synonyms found at PubChem are:
Gallacetophenone, 528-21-2, 1-(2,3,4-Trihydroxyphenyl)ethanone, 2',3',4'-TRIHYDROXYACETOPHENONE, Galloacetophenone, Alizarin Yellow C, 2,3,4-Trihydroxyacetophenone, Alizarine Yellow C, Ethanone, 1-(2,3,4-trihydroxyphenyl)-, C.I. 57000, 4-Acetylpyrogallol, NSC 66553, Acetophenone, 2',3',4'-trihydroxy-, UNII-C70E921C4P, 1-(2,3,4-Trihydroxyphenyl)ethan-1-one, 2,3,4-Trihydroxyacetophenone oxime, EINECS 208-430-2, CHEMBL242540, XIROXSOOOAZHLL-UHFFFAOYSA-N, C70E921C4P, 1-acetyl-2,3,4-trihydroxybenzene, Gallacetophenon, Acetophenone, 2,3,4-trihydroxy-, PubChem3246, Gallacetophenone, 97%, AC1L1VRW, AC1Q1JHR, 2,4-Trihydroxyacetophenone, WLN: QR BQ CQ DV1, SCHEMBL105704, ACMC-209l21, 4-Acetylbenzene-1,2,3-triol, DTXSID2060179, 2,4-Trihydroxyacetophenone oxime, Acetophenone,3',4'-trihydroxy-, CTK4J6571, Ethanone,3,4-trihydroxyphenyl)-, MolPort-000-482-961, ZINC156821, ALBB-015601, KS-000014EE, NSC66553, Acetophenone, 2,3,4-trihydroxy-,, 2', 3', 4'-trihydroxyacetophenone, ANW-31559, BBL027373, BDBM50234652, CG-021, HTS001839, NSC-66553, SBB058153, STK519460, AKOS002214745, ACN-049222, BS-3913, MCULE-2947155299, VZ21769, 1-(2,3,4-trihydroxy-phenyl)-ethanone, Ethanone,1-(2,3,4-trihydroxyphenyl)-, 1-(2,3,4-trihydroxyphenyl)-1-ethanone, 1-[2,3,4-tris(oxidanyl)phenyl]ethanone, AN-45582, BP-12555, LS-13726, ZB006449, C.I.57000, TC-120304, FT-0632303, R1036, ST45210508, 2\',3\',4\'-TRIHYDROXYACETOPHENONE, A829268, S01-0443, W-105794, Z57124116, InChI=1/C8H8O4/c1-4(9)5-2-3-6(10)8(12)7(5)11/h2-3,10-12H,1H

ID: 2587

chemical graph of compound 2587



InChIKey: XJGONMZLEDGBRM-UHFFFAOYSA-M
SMILES: CC[N+](CC)(CC)CCC(C1CCCCC1)(C2=CC=CC=C2)O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 20298
synonyms found at PubChem are:
Tridihexethyl chloride, Pathilon chloride, 4310-35-4, EINECS 224-323-3, (3-Cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammonium chloride, Tridihexethyl chloride [BAN], CHEBI:9703, 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium chloride, AMMONIUM, (3-CYCLOHEXYL-3-HYDROXY-3-PHENYLPROPYL)TRIETHYL-, CHLORIDE, Tridihexethyl chloride (BAN), 60-49-1 (Parent), Benzenepropanaminium, gamma-cyclohexyl-N,N,N-triethyl-gamma-hydroxy-, chloride, (3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium;chloride, Pathilon (TN), Tridihexethyl chloride [USP:INN:BAN], NCGC00017006-01, DSSTox_CID_3701, AC1L2FZ7, C21H36NO.Cl, DSSTox_RID_77155, DSSTox_GSID_23701, MLS002154119, SCHEMBL100471, CHEMBL1200771, DTXSID4023701, Tridihexethyl chloride(200 mg), HMS1571A06, HMS2098A06, HMS2233A09, HMS3373K12, HMS3715A06, Tox21_110733, ACM4310354, CCG-221042, TRIDIHEXETHYL CHLORIDE (200 MG), LS-17260, SMR001233426, CAS-4310-35-4, D00723, SR-01000838833, SR-01000838833-2, (3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium chloride

ID: 2588

chemical graph of compound 2588



InChIKey: XJHDMGJURBVLLE-BOCCBSBMSA-N
SMILES: C[C@H]1[C@@H]2CC[C@]3(C=CC(=O)C(=C3[C@H]2OC1=O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 221071
synonyms found at PubChem are:
santonin, alpha-Santonin, 481-06-1, (-)-alpha-Santonin, Santoninic anhydride, UNII-1VL8J38ERO, Semenen, (-)-Santonin, NSC4900, (-)-Santonine, 1VL8J38ERO, Santoninum, CHEBI:16363, L-alpha-Santonin, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g][1]benzofuran-2,8-dione, DSSTox_CID_25312, DSSTox_RID_80795, DSSTox_GSID_45312, NSC 4900, EINECS 207-560-7, l-.alpha.-Santonin, NSC 41311, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,9b-tetrahydro-3H-benzo[g]benzofuran-2,8-dione, (3S,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)dione, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione, AI3-19471, (-)-.alpha.-Santonin, Santonin [JAN:NF], SR-01000635568, 11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone, (3S)-2,3,3a,4,5,5a,8,9bbeta-Octahydro-3,5abeta,9-trimethylnaphtho(1,2-b)furan-2,8-dion, Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone, (11S)-(-)-, Naphtho(1,2-b)puran-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, NCGC00016461-01, Santonin (TN), CAS-481-06-1, naphtho[1,2-b]furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-, ()-alpha-Santonin, SANTONINE, Santonin (JP17), (-)-|A-Santonin, Spectrum_000790, SpecPlus_000318, Prestwick0_001070, Prestwick1_001070, Prestwick2_001070, Prestwick3_001070, Spectrum2_000699, Spectrum3_001245, Spectrum4_001476, Spectrum5_000151, UPCMLD-DP084, AC1L59QF, BSPBio_001060, BSPBio_002750, KBioGR_002051, KBioSS_001270, SPECTRUM300542, MLS002154141, DivK1c_006414, SPBio_000857, SPBio_002970, BPBio1_001166, CHEMBL259254, MEGxp0_001636, SCHEMBL1133565, DTXSID7045312, UPCMLD-DP084:001, KBio1_001358, KBio2_001270, KBio2_003838, KBio2_006406, KBio3_002250, (-)-alpha-Santonin, >=99%, Eudesma-1,4-dien-12-oic acid, 6-alpha-hydroxy-3-oxo-, gamma-lactone, (11S)-, MolPort-002-507-204, HMS1571E22, HMS2098E22, HMS2268H12, (3S,3aS,5aS,9bS)-2,3,3a,4,5,5a,8,9b-Octahydro-3,5a,9-trimethylnaphtho(1,2-b)furan-2,8-dione, Naphtho(1,2-b)furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-, Naphtho[1,2-b]furan-2,8(3H,4H)-dione,3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-, NSC-4900, ZINC3881689, Tox21_110445, ANW-41289, CCG-40021, MFCD00135865, AKOS015895177, Tox21_110445_1, API0024774, LMPR0103190001, MCULE-4974199679, SDCCGMLS-0066491.P001, (-)-alpha-Santonin, analytical standard, NCGC00161640-01, NCGC00161640-02, NCGC00161640-03, NCGC00263447-01, SMR000112520, TR-031390, AB00376930, S0521, C02206, D00154, WLN: T B566 COV LV IHTT&J E1 I1 M1, A827469, SR-01000635568-1, SR-01000635568-4, SR-01000635568-5, BRD-K58787433-001-05-4, BRD-K58787433-001-08-8, BRD-K58787433-001-12-0, Santonin, European Pharmacopoeia (EP) Reference Standard, 11-Epiisoeusantona-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, Eudesma-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, (11S)-, (11S)-6alpha-hydroxy-3-oxoeudesma-1,4-dien-12-oic acid gamma-lactone, 6alpha-hydroxy-3-oxo-11-epiisoeusantona-1,4-dienic acid gamma-lactone, Eudesma-1, 6.alpha.-hydroxy-3-oxo-, .gamma.-lactone, (11S)-(-)-, Naphtho[1,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, 3a,5,5a,9b-Tetrahydro-3,5a,9-trimethyl-naphtho[1,2-b]puran-2,8(3H,4H)-dione, (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-3a,4,5,5a-tetrahydronaphtho[1,2-b]furan-2,8(3H,9bH)-dione, (3S,3aS,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione, 1,3,4,4a,7-Hexahydro-1-hydroxy-.alpha., 4a,8-trimethyl-7-oxo-2-naphthaleneacetic acid .gamma.-lactone, 881738-49-4, InChI=1/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s, Naphtho[1,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, [3S-(3.alpha.,3a.alpha.,5a.beta.,9b.beta.)]-

ID: 2589

chemical graph of compound 2589



InChIKey: XJKZZVPYOOIMPE-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3642305
synonyms found at PubChem are:
SUPROFEN METHYL ESTER, KBio2_007648, AC1MUKHI, Spectrum_001963, Spectrum2_001366, Spectrum3_001051, Spectrum4_001191, Spectrum5_001913, BSPBio_002602, KBioGR_001881, KBioSS_002520, SPECTRUM1500779, SPBio_001292, SCHEMBL9085209, CHEMBL1474177, CHEBI:93807, KBio2_002512, KBio2_005080, KBio3_001822, methyl p-(2-thenoyl)hydratropate, XJKZZVPYOOIMPE-UHFFFAOYSA-N, HMS1921I08, CCG-38981, NCGC00094853-01, NCGC00094853-02, NCGC00094853-03, methyl alpha-[p-(2-thienylcarbonyl)phenyl]propionate, BRD-A11154023-001-02-8, methyl 2-[4-(thiophene-2-carbonyl)phenyl]propanoate, (+/-)-alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid methyl ester

ID: 2590

chemical graph of compound 2590



InChIKey: XJLATMLVMSFZBN-VYDXJSESSA-N
SMILES: CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 443600
synonyms found at PubChem are:
actinonin, Actinonine, UNII-P18SPA8N0K, P18SPA8N0K, CHEMBL308333, 13434-13-4, Octanohydroxamic acid, 3-((1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamoyl)-, 2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEPTANOIC ACID [1-(2-HYDROXYMETHYL-PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL]-AMIDE, BB2, Butanediamide, N4-hydroxy-N1-(1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)-2-pentyl-, stereoisomer, SR-01000075681, (?)-Actinonin, 3g5k, 3m6p, 3m6q, 3m6r, 3pn4, 4dr9, 4je7, Spectrum2_000628, Spectrum3_000680, Spectrum4_001932, Spectrum5_000728, D0T2IQ, AC1L9EW8, Lopac0_000010, BSPBio_002379, KBioGR_002305, DivK1c_001024, SCHEMBL279450, SPBio_000596, HMS503M09, KBio1_001024, KBio3_001599, MolPort-003-666-102, NINDS_001024, C19H35N3O5, HMS3260A21, (2R)-2-[2-(hydroxyamino)-2-oxo-ethyl]-N-[(1S)-1-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-2-methyl-propyl]heptanamide, (R)-N4-hydroxy-N1-((S)-1-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-2-pentylsuccinamide, N*4*-Hydroxy-N*1*-[1-(2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide, ZINC3979014, Tox21_500010, BDBM50089194, CCG-38543, AKOS015894413, DB04310, LP00010, IDI1_001024, NCGC00093535-01, NCGC00093535-02, NCGC00093535-03, NCGC00093535-04, NCGC00260695-01, AJ-47578, LS-97940, EU-0100010, A 6671, C12056, A806765, I04-9250, SR-01000075681-1, SR-01000075681-5, Actinonin in combination with isoniazid and rifampicin, BRD-K24621118-001-02-5, BRD-K24621118-001-03-3, (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide, (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide, (2R)-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-N'-oxidanyl-2-pentyl-butanediamide, (R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide, N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-(R)-pentyl-succinamide

ID: 2591

chemical graph of compound 2591



InChIKey: XJLGXHIRSHTRPQ-UHFFFAOYSA-N
SMILES: CCCN1C(=O)C2=C(N=C(N2)C3CCCC3)N(C1=O)CCCOC(=O)C4=CC=C(C=C4)S(=O)(=O)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 133012
synonyms found at PubChem are:
FSCPX, 156547-56-7, CHEMBL327708, FSCPX xanthine, 8-Cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine, 8-Cyclopentyl-N3-[3-(4-(fluorosulfonyl)benzoyloxy)propyl]-N1-propylxanthine, Lopac-F-7927, Lopac0_000507, SCHEMBL787826, CTK8E7915, DTXSID00166094, HMS3261F15, AC1L3209, Tox21_500507, BDBM50039676, API0008487, CCG-204598, LP00507, NCGC00015447-01, NCGC00015447-02, NCGC00015447-03, NCGC00015447-04, NCGC00093905-01, NCGC00093905-02, NCGC00261192-01, EU-0100507, F 7927, SR-01000075884, J-009310, SR-01000075884-1, 3-(8-cyclopentyl-2,6-dioxo-1-propyl-7H-purin-3-yl)propyl 4-fluorosulfonylbenzoate, 4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-purin-3-yl)-propyl ester, 4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-purin-3-yl)-propyl ester(FSCPX)

ID: 2592

chemical graph of compound 2592



InChIKey: XJLSEXAGTJCILF-UHFFFAOYSA-N
SMILES: C1CC(CNC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4498
synonyms found at PubChem are:
nipecotic acid, 3-Piperidinecarboxylic acid, Piperidine-3-carboxylic acid, 498-95-3, (+/-)-Nipecotic acid, hexahydronicotinic acid, h-dl-nip-oh, EINECS 207-873-9, (+/-)-3-piperidine carboxylic acid, CHEMBL277498, 60252-41-7, dl-piperidine-3-carboxylic acid, CHEBI:116931, XJLSEXAGTJCILF-UHFFFAOYSA-N, SR-01000075612, Nipecotic, h-nip-oh, 3-carboxypiperidine, (y)-Nipecotic acid, ( inverted exclamation markA)-Nipecotic acid, (?)-Nipecotic acid, (RS)-nipecotic acid, D-nipecotic acid-HCl, h-dl-pic(3)-oh, PubChem6793, Nipecotic acid, 98%, Spectrum_000353, ACMC-209ghf, ACMC-209kiv, AC1L1IAV, Prestwick0_000950, Prestwick1_000950, Prestwick2_000950, Prestwick3_000950, Spectrum2_001184, Spectrum3_001712, Spectrum4_000169, Spectrum5_001412, (A+/-)-Nipecotic acid, (R)-(-)-Nipecoticacid, 3-PiperidinecarboxylicAcid, (+/-)-beta-Homoproline, nipecotic acid (+/-)-, ACMC-209m9w, D0RF2M, piperidin-3-carboxylic acid, 3-piperidine carboxylic acid, Lopac0_000041, SCHEMBL85677, BSPBio_000920, BSPBio_003324, KBioGR_000657, KBioSS_000833, MLS000069598, DivK1c_000148, SPECTRUM2300345, SPBio_001227, SPBio_003079, AC1Q1H56, BPBio1_001012, GTPL4564, CTK1D6899, HMS500H10, KBio1_000148, KBio2_000833, KBio2_003401, KBio2_005969, KBio3_002544, MolPort-000-141-415, NINDS_000148, HMS1570N22, HMS2097N22, HMS2235L11, HMS3260I03, ACT02108, KS-00000AD8, Tox21_500041, AN-673, ANW-30869, BBL018520, BDBM50003624, CCG-40009, FC1297, MFCD00005992, PDSP1_000143, PDSP2_000142, SBB027313, STL193988, (+/-)-piperidine-3-carboxylic acid, AKOS000120441, AKOS016347225, AC-2538, CS-W020556, LP00041, LS20781, MCULE-3189529983, PS-6088, RP00910, RTC-062177, TRA0059440, TRA0087179, VP80061, 3-piperidinecarboxylic acid 498-95-3, IDI1_000148, MLS-0072915, ( inverted question mark)-Nipecotic acid, [J Neurochem 25: 797 (1975), NCGC00014992-03, NCGC00014992-04, NCGC00014992-05, NCGC00014992-06, NCGC00014992-07, NCGC00014992-08, NCGC00024510-02, NCGC00024510-03, NCGC00024510-04, NCGC00024510-05, NCGC00260726-01, BR-35333, KB-50362, KB-58347, KB-59741, SC-04844, SMR000059031, SY001864, MLS-0072915.P019, AB0006610, AB1001262, DB-022674, LS-114607, ST2417840, TC-062177, TL8003313, 4CH-017819, A5098, AB00052417, AM20100216, C3380, EU-0100041, FT-0604479, FT-0693391, N0420, Piperidine-3-carboxylic acid(nipecotic acid), ST50998283, A16064, B-1328, K-9252, M-3455, I12-0028, I12-0093, Q-200393, SR-01000075612-1, SR-01000075612-2, W-106000, I14-23579, ( inverted question mark)-3-Piperidine carboxylic acid, F0001-1300, 276253-19-1

ID: 2593

chemical graph of compound 2593



InChIKey: XJMOSONTPMZWPB-UHFFFAOYSA-M
SMILES: CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 104981
synonyms found at PubChem are:
propidium iodide, 25535-16-4, Propidium diiodide, 3,8-Diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridin-5-ium iodide, Propidium (Iodide), UNII-TP416O228T, EINECS 247-081-0, NSC 169541, 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide, CHEBI:51240, TP416O228T, 3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridinium diiodide, 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium iodide methiodide, Phenanthridinium, 3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-, diiodide, CHEMBL345124, SR-01000841195, Propidium Iodine, Prestwick_1017, AC1L2XTW, SCHEMBL14996, KS-00000XQE, BIP4355, MolPort-003-929-149, XJMOSONTPMZWPB-UHFFFAOYSA-M, ZX-AFC000136, C27H34I2N4, HMS1570O06, HMS2097O06, HMS3403D19, HMS3714O06, BCP29152, HY-D0815, 2090AB, GP2610, MFCD00011921, AKOS015904636, 36015-30-2 (f. base), CCG-220792, CS-7538, 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium iodide methiodide (6CI), ACM25535164, AK114464, AX8149234, KB-234387, LS-102865, B7758, FT-0674066, Propidium Iodide solution, 1.0 mg/ml in water, C-45729, SR-01000841195-2, I14-17444, 3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-phenanthridiniudii, 3,8-diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridinium iodide, 3,8-diamino-5-{3-[diethyl(methyl)ammonio]propyl}-6-phenylphenanthridinium diiodide, 3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide, 3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazaniumdiiodide, 29968-EP2270014A1, 29968-EP2272839A1, 29968-EP2272840A1, 29968-EP2280011A1, 29968-EP2289892A1, 29968-EP2295416A2, 29968-EP2295424A1, 29968-EP2298748A2, 29968-EP2308860A1, 29968-EP2311464A1, 29968-EP2311806A2, 29968-EP2374454A1

ID: 2594

chemical graph of compound 2594



InChIKey: XJNUHVMJVWOYCW-UHFFFAOYSA-N
SMILES: C1CCC(C(C1)N2CCC(CC2)C3=CC=CC=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 212231
synonyms found at PubChem are:
VESAMICOL HYDROCHLORIDE, AH 5183 hydrochloride, 120447-62-3, AH-5183 hydrochloride, 2-(4-Phenylpiperidino)cyclohexanol hydrochloride, Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride, AH-5183, 23965-53-9, V-100, SR-01000075352, (+/-)-VESAMICOL, AC1L4SHB, (+/-)-Vesamicol HCl, D-(+)-VESAMICOL, ( inverted exclamation markA)-2-(4-phenylpiperidino)cyclohexanol hydrochloride, (y)-Vesamicol hydrochloride, AC1Q3F8M, (?)-Vesamicol hydrochloride, L(-)-vesamicol hydrochloride, SPECTRUM2300309, CHEMBL1256846, CTK8F1086, HMS1570H22, HMS1922L20, Pharmakon1600-02300309, 22232-64-0 (Parent), Tox21_501228, MFCD00055231, NSC759580, CCG-222532, LP01228, NSC-759580, (+/-)-Vesamicol HCl (AH-5183), (+/-)-Vesamicol.HCl (AH-5183), NCGC00094470-01, NCGC00094470-02, NCGC00094470-03, NCGC00094470-04, NCGC00261913-01, LS-57227, RT-016206, (+/-)-2-(4-Phenylpiperidino) cyclohexanol, EU-0101228, (+/-)-Vesamicol hydrochloride, >98%, solid, ( inverted question mark)-Vesamicol hydrochloride, J-004345, SR-01000075352-1, AH-5183((+/-)-2-(4-Phenylpiperidino) cyclohexanol, ( inverted exclamation markA)-Vesamicol HCl (AH-5183), (+/-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride, 2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol hydrochloride

ID: 2595

chemical graph of compound 2595



InChIKey: XJOOMMHNYOJWCZ-UKRRQHHQSA-N
SMILES: CC1=C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 73484
synonyms found at PubChem are:
Agroclavine, 8,9-Didehydro-6,8-dimethylergoline, 548-42-5, UNII-A8SW57GO7T, (-)-agroclavine, CCRIS 2099, Ergoline, 8,9-didehydro-6,8-dimethyl-, (5R,10R)-agroclavine, EINECS 208-947-3, 6,8-Dimethyl-8,9-didehydroergoline, NSC 93132, AGROCLAVIN, BRN 0024966, A8SW57GO7T, CHEBI:2519, CHEMBL449081, Indolo(4,3-fg)quinoline, 4,6,6a,7,8,10a-hexahydro-7,9-dimethyl-, NSC93132, (6aR,10aR)-7,9-dimethyl-4,6,6a,7,8,10a-hexahydroindolo[4,3-fg]quinoline, agroclavine-1, Lopac-A-206, AC1L2JXJ, Biomol-NT_000066, D03CEZ, Lopac0_000128, 4-23-00-01623 (Beilstein Handbook Reference), cid_73484, MLS001216424, SCHEMBL183368, BPBio1_001357, CTK2J1763, XJOOMMHNYOJWCZ-UKRRQHHQSA-N, 89708-38-3, ZINC1604018, BDBM50016490, 8,9-Didehydro-6,8-dimethyl-ergoline, CCG-204223, NCGC00015018-01, NCGC00163164-01, LS-64401, SMR000544202, EU-0100128, C09023, SR-01000075354, SR-01000075354-1, 7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline, Indolo[4,3-fg]quinoline, 4,6,6a,7,8,10a-hexahydro-7,9-dimeth, (6aR,10aR)-7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline, 7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline (Agroclavine)

ID: 2596

chemical graph of compound 2596



InChIKey: XJYLCCJIDYSFMB-UHFFFAOYSA-N
SMILES: CC(=O)NC1=CC2=CC=CC=C2OC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 136620
synonyms found at PubChem are:
3-Acetamidocoumarin, 779-30-6, N-(2-Oxo-2H-chromen-3-yl)acetamide, 3-acetamido-coumarin, 3-Acetylaminocoumarin, 3-(Acetylamino)coumarin, N-(2-oxochromen-3-yl)acetamide, N1-(2-oxo-2H-chromen-3-yl)acetamide, A1-01398, SR-01000389251, NSC65873, PubChem8662, Maybridge1_000258, Prestwick0_000969, Prestwick1_000969, Prestwick2_000969, Prestwick3_000969, ChemDiv2_000143, AC1Q1L2N, Oprea1_480692, BSPBio_000977, CBDivE_000070, MLS000719859, CHEMBL63349, SCHEMBL893303, SPBio_002898, AC1L38X7, BPBio1_001075, CHEBI:95324, CTK5E5200, HMS542D16, ZINC67488, DTXSID80228528, MolPort-002-130-122, XJYLCCJIDYSFMB-UHFFFAOYSA-N, HMS1369G11, HMS1571A19, HMS2098A19, HMS2616G21, BCP20917, BTB 01088, CCG-15095, NSC 65873, NSC-65873, AKOS005202961, MCULE-8239666346, TRA0010184, VZ26206, N-(2-oxo-1-benzopyran-3-yl)acetamide, NCGC00016539-01, NCGC00016539-02, NCGC00179352-01, CAS-779-30-6, CC-13900, KB-29284, N-(2-Oxo-2H-chromen-3-yl)acetamide #, OR345139, SMR000304388, ZB002570, N-(2-oxidanylidenechromen-3-yl)ethanamide, DB-022150, N-(2-Oxo-2H-1-benzopyran-3-yl)acetamide, A2972, AB00513981, FT-0614856, ST50319576, Acetamide,N-(2-oxo-2H-1-benzopyran-3-yl)-, A839295, C-09857, SR-01000389251-1, SR-01000389251-2, SR-01000389251-4, BRD-K85104575-001-03-2, BRD-K85104575-001-07-3, InChI=1/C11H9NO3/c1-7(13)12-9-6-8-4-2-3-5-10(8)15-11(9)14/h2-6H,1H3,(H,12,13

ID: 2597

chemical graph of compound 2597



InChIKey: XKFPYPQQHFEXRZ-UHFFFAOYSA-N
SMILES: CC1=CC(=NO1)C(=O)NNCC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3759
synonyms found at PubChem are:
isocarboxazid, 59-63-2, Isocarboxazide, Marplan, Isocarbonazid, Benazide, Enerzer, Isocarbossazide, Isocarboxyzid, N'-Benzyl-5-methylisoxazole-3-carbohydrazide, Marplon, Isocarbossazide [DCIT], Isocarboxazida, Isocarboxazidum, Maraplan, Isocarboxazide [INN-French], Isocarboxazidum [INN-Latin], Isocarboxazida [INN-Spanish], Isocarboxizid, BMIH, Ro 5-0831/1, Ro 5-0831, Isocarboxazid [INN:BAN], N'-Benzyl N-methyl-5-isoxazolecarboxylhydrazide-3, 3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide, 5-Methyl-3-isoxazolecarboxylic acid 2-benzylhydrazide, Marplan (TN), NSC 169893, CCRIS 9178, Isocarboxazid (INN), N'-benzyl-5-methyl-1,2-oxazole-3-carbohydrazide, UNII-34237V843T, EINECS 200-438-4, BRN 0201295, 1-Benzyl-2-(5-methyl-3-isoxazolyl-carbonyl)hydrazine, MLS003106729, 3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide, 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine, CAS-59-63-2, NCGC00016267-01, 34237V843T, 5-methyl-N'-(phenylmethyl)isoxazole-3-carbohydrazide, SMR001233334, SR-01000841192, Isocarboxazid [USP:INN:BAN], Isocarboxazid (ICD), AC1L1GNE, Prestwick0_000795, Prestwick1_000795, Prestwick2_000795, Prestwick3_000795, DSSTox_CID_3171, D0I2VK, DSSTox_RID_76902, DSSTox_GSID_23171, SCHEMBL49562, BSPBio_000930, 4-27-00-03999 (Beilstein Handbook Reference), MLS002154005, SPBio_002869, BPBio1_001024, GTPL7204, ZINC1587, CHEMBL1201168, DTXSID4023171, WLN: T5NOJ C1 EVMM1R, CHEBI:93635, CTK8B7692, XKFPYPQQHFEXRZ-UHFFFAOYSA-N, BDBM163692, HMS1570O12, HMS2097O12, HMS2230E11, HMS3369G18, HMS3714O12, Tox21_110336, ANW-58213, NSC169893, Ro5-0831, AKOS016003091, API0000611, CCG-220795, DB01247, FCH2716017, NSC-169893, NCGC00016267-02, NCGC00016267-03, AC-24841, AJ-08053, BC645218, LS-86607, AX8135097, KB-258619, TC-146958, AB00513923, FT-0670438, Y0484, 3-Isoxazolecarboxylic acid, 2-benzylhydrazide, D02580, N'-Benzyl-5-methyl-3-isoxazolecarbohydrazide #, SR-01000841192-2, SR-01000841192-3, 3-(2-BENZYLHYDRAZOCARBOXY)-5-METHYL-ISOXAZOLE, 3-Isoxazolecarboxylic acid, 2-(phenylmethyl)hydrazide, 5-methyl-N'-(phenylmethyl)-3-isoxazolecarbohydrazide, BRD-K93332168-001-03-2, Isocarboxazid 5-methyl-3-isoxazole-carboxylic acid 2-benzylhydrazide, AldrichCPR

ID: 2598

chemical graph of compound 2598



InChIKey: XKWWCTISHMFHJB-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C2=C(O1)C=C3C(=C2O)C(=O)C(=O)C(=C3O)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6710774
synonyms found at PubChem are:
RHODOCLADONIC ACID, SPBio_001614, Spectrum2_001687, Spectrum3_001818, Spectrum4_001850, AC1O8K2P, BSPBio_003435, KBioGR_002260, CHEMBL3039103, KBio3_002938, CCG-38774, NCGC00178066-01, SR-05000002578, SR-05000002578-1, 2-acetyl-3,4,8-trihydroxy-7-methoxybenzo[f][1]benzofuran-5,6-dione

ID: 2599

chemical graph of compound 2599



InChIKey: XLBIBBZXLMYSFF-UHFFFAOYSA-M
SMILES: CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13)C(C)C.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9279
synonyms found at PubChem are:
PROPANTHELINE BROMIDE, 50-34-0, Pro-Banthine, Propantheline (bromide), Neometantyl, Neopepulsan, Corrigast, Ercorax, Ercotina, Ketaman, Kivatin, Pantheline, Pervagal, Probantine, Prodixamon, Propantel, Pantas, Pro-Gastron, UNII-UX9Z118X9F, CCRIS 6271, NCI-C56257, Propanthelini bromidum [INN-Latin], Propantelina bromuro, Propantelina bromuro [DCIT], EINECS 200-030-6, Bromuro de proantelina [INN-Spanish], Bromure de propantheline [INN-French], Propanthelini bromidum, SC-3171, (2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate, Bromuro de proantelina, Bromure de propantheline, MLS000028703, UX9Z118X9F, Propanthel, NCGC00094306-02, SMR000058661, Diisopropyl(2-hydroxyethyl)methylammonium bromide xanthene-9-carboxylate, DSSTox_CID_3519, Pro-Banthine (TN), DSSTox_RID_77062, Xanthene-9-carboxylic acid, ester with (2-hydroxyethyl)diisopropylmethylammonium bromide, DSSTox_GSID_23519, 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-ylcarbonyl)oxy)ethyl)-, bromide, Propantheline bromide [USAN:INN:BAN:JAN], Ammonium, diisopropyl(2-hydroxyethyl)methyl-, bromide, xanthene-9-carboxylate, C23H30NO3, CAS-50-34-0, SR-01000003171, P 8891, methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide, N-(2-(9H-xanthene-9-carbonyloxy)ethyl)-N-isopropyl-N-methylpropan-2-aminium bromide, Propantheline,(S), 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-ylcarbonyl)oxy)ethyl)-, bromide (1:1), 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-, bromide (1:1), Prestwick_241, 2-Hydroxyethyl]diisopropylmethyl-ammonium bromide xanthene-9-carboxylate, methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide, (2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate bromide, Propantheline bromide [USP:INN:BAN:JAN], N-methyl-N-(1-methylethyl)-N-{2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide, Opera_ID_1667, AC1L1SQ1, CHEMBL1240, REGID_for_CID_9279, SCHEMBL40291, MLS001076547, MLS001333690, SPECTRUM1500511, CHEBI:8482, DTXSID2023519, CTK8G2596, HMS502I04, MolPort-003-666-273, HMS1570F15, HMS1920L18, HMS2092C19, HMS2097F15, HMS2234M23, HMS3259E04, HMS3263K09, HMS3370N21, HMS3714F15, Pharmakon1600-01500511, HY-B1188, KS-000018AO, Tox21_111265, Tox21_302331, Tox21_501014, CCG-39238, MFCD00050291, NSC757294, AKOS015895527, Tox21_111265_1, API0003947, CS-4797, KS-1386, LP01014, LS-1304, NC00529, NSC-757294, Propantheline bromide (JP17/USP/INN), NCGC00015854-10, NCGC00094306-01, NCGC00094306-03, NCGC00094306-04, NCGC00094306-05, NCGC00255145-01, NCGC00261699-01, AC-13428, AN-41551, CPD000058661, SAM002554922, TL8003337, EU-0101014, FT-0603218, V0361, Propantheline bromide, >=97% (TLC), powder, D00481, A828073, SR-01000003171-2, SR-01000003171-4, SR-01000003171-7, W-105970, 2-Hydroxyethyl]diisopropylmethyl- ammonium bromide xanthene-9-carboxylate, diisopropyl(methyl)[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide, diisopropyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium bromide, Propantheline bromide, United States Pharmacopeia (USP) Reference Standard, methyl-[2-[oxo(9H-xanthen-9-yl)methoxy]ethyl]-di(propan-2-yl)ammonium bromide, methyl-di(propan-2-yl)-[2-(9H-xanthen-9-ylcarbonyloxy)ethyl]azanium bromide, Propantheline Bromide, Pharmaceutical Secondary Standard; Certified Reference Material, SUCSGEMABNZXAU-UHFFFAOYSA-N

ID: 2600

chemical graph of compound 2600



InChIKey: XLDKUDAXZWHPFH-UHFFFAOYSA-N
SMILES: C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9384
synonyms found at PubChem are:
Spermine tetrahydrochloride, 306-67-2, N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride, Gerontine tetrahydrochloride, Neuridine tetrahydrochloride, N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride, Musculamine tetrahydrochloride, UNII-9CI1570O48, EINECS 206-189-8, NSC 69852, Geontine Tetrahydrochloride, SPERMINE HCL, 1,4-BUTANEDIAMINE, N,N'-BIS(3-AMINOPROPYL)-, TETRAHYDROCHLORIDE, SPERMINE, TETRAHYDROCHLORIDE, 4,9-Diazoniadodecamethylenediammonium tetrachloride, 1,4-Bis(aminopropyl)butanediamine tetrahydrochloride, 9CI1570O48, 1,4-Butanediamino, N,N'-bis(3-aminopropyl), tetrahydrochloride, 1,4-Butanediamine, N1,N4-bis(3-aminopropyl)-, hydrochloride (1:4), S-7500, Spermine tetra, HCl, SR-01000075473, CCRIS 8452, Spermine tetra HCl, ACMC-209hhm, AC1L1SXD, AC1Q3ABE, AC1Q3ABF, C10H30Cl4N4, CHEMBL1556584, DTXSID0059792, CTK3J7097, BIS5943, MolPort-001-801-284, XLDKUDAXZWHPFH-UHFFFAOYSA-N, ZX-AFC000501, Spermine tetrahydrochloride, powder, KS-000013QA, Tox21_501077, ANW-26936, BN0499, MFCD00012914, SBB058640, AKOS015845172, AKOS016015902, CCG-222381, LP01077, MCULE-4500869266, RTR-030733, ACM306672|1, NCGC00094355-01, NCGC00261762-01, AK126527, LS-45649, Spermine tetrahydrochloride 0.1 M solution, AX8151800, KB-300118, TR-030733, B6522, EU-0101077, FT-0631926, ST24048684, ST50411732, V5045, Spermine tetrahydrochloride, >=99.0% (AT), K-7325, S 2876, Spermine tetrahydrochloride, Vetec(TM) reagent grade, SR-01000075473-2, SR-01000075473-4, 1,4-Bis (Aminopropyl) Butanediamine Tetrahydrochloride, N,N'-Bis(3-aminopropyl)-1,4-butanediamineTetrahydrochloride, N,N'-bis(3-aminopropyl)butane-1,4-diamine tetrahydrochloride, N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride, N,N-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride, Spermine tetrahydrochloride, BioReagent, for molecular biology, N1,N1'-(butane-1,4-diyl)dipropane-1,3-diamine tetrahydrochloride, (3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amine tetrahydrochloride, N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE, TETRAHYDROCHLORIDE, N1,N1'-(Butane-1,4-diyl);bis(propane-1,3-diamine); tetrahydrochloride, Spermine tetrahydrochloride, BioUltra, for molecular biology, >=99.5% (AT), Spermine tetrahydrochloride, certified reference material, TraceCERT(R), (3-aminopropyl){4-[(3-aminopropyl)amino]butyl}amine, chloride, chloride, chlor ide, chloride, N,N inverted exclamation marka-E<<(3- degrees +/-+/-u>>u)-1,4- paragraph sign inverted exclamation mark paragraph signthorn degrees . EANIEaNI, Spermine tetrahydrochloride, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, N,N'-Bis-(3-Aminopropyl)-1,4-Diaminobutane Tetrahydrochloride

ID: 2601

chemical graph of compound 2601



InChIKey: XLEYFDVVXLMULC-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=C(C=C1O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 68073
synonyms found at PubChem are:
480-66-0, 1-(2,4,6-Trihydroxyphenyl)ethanone, 2',4',6'-Trihydroxyacetophenone, PHLOROACETOPHENONE, Phloracetophenone, Acetophloroglucine, Acetylphloroglucinol, 2,4,6-Trihydroxyacetophenone, Ethanone, 1-(2,4,6-trihydroxyphenyl)-, 2-Acetylphloroglucinol, 1-(2,4,6-Trihydroxyphenyl)-ethanone, THAP, monoacetylphloroglucinol, Phloracetophene, 1-(2,4,6-Trihydroxyphenyl)ethan-1-one, NSC 54927, UNII-8L7XD8830T, EINECS 207-556-5, Acetophenone, 2',4',6'-trihydroxy-, 1-(2,4,6-trihydroxy-phenyl)-ethanone, 2,4,6-trihydroxy acetophenone, CHEMBL452477, CHEBI:64344, XLEYFDVVXLMULC-UHFFFAOYSA-N, 2,4,6-TRIHYDROXYACETOPHENONE MONOHYDRATE, 8L7XD8830T, PHLOROACETOPHENONE MONOHYDRATE, 2\',4\',6\'-Trihydroxyacetophenone, 2-ACETYLPHLOROGLUCINOL MONOHYDRATE, Acetophenone, 2',4',6'-trihydroxy- (8CI), 1-acetyl-2,4,6-trihydroxybenzene, 1-(2,4,6-trihydroxyphenyl]ethanone, 2-Acetylbenzene-1,3,5-triol monohydrate, 2',4',6'-TRIHYDROXYACETOPHENONE HYDRATE, 1-(2,4,6-Trihydroxyphenyl)ethan-1-one monohydrate, Acetophloroglucinol, NSC54927, PubChem3402, THAP MONOHYDRATE, Spectrum2_001989, AC1Q5D4N, SPECTRUM300604, 2',6'-Trihydroxyacetophenone, SCHEMBL105416, SPBio_002177, 2-Acetyl-1,3,5-benzenetriol, 2-Acetylbenzene-1,3,5-triol, AC1L28Z5, DTXSID5060061, PHLOROACETOPHENONE HYDRATE, 2, 4, 6-trihydroxyacetophenone, Acetophenone,4',6'-trihydroxy-, ACon1_001026, Ethanone,4,6-trihydroxyphenyl)-, MolPort-001-739-526, 1-(2,6-Trihydroxyphenyl)ethanone, ZINC157773, ALBB-015674, 2',4',6'-Trihydroxy-Acetophenone, 2',4',6'-Trihydroxyaceto-phenone, ANW-73967, BDBM50249070, CCG-39527, HTS001840, LABOTEST-BB LT00000181, LABOTEST-BB LT03330227, MFCD00149091, NSC-54927, SBB056557, STL194090, AKOS005175228, 1-(2,4, 6-Trihydroxyphenyl)ethanone, AS01157, CS-W008226, MCULE-7150082883, PS-5270, RL03795, SDCCGMLS-0066935.P001, TRA0053003, VZ21791, KS-0000025F, NCGC00095604-01, NCGC00095604-02, 1-[2,4,6-tris(oxidanyl)phenyl]ethanone, 2,4,6-TRIHYDROXYACETOPHENONE H2O, 4CN-1457, AC-12835, AJ-15105, AN-15524, CJ-01714, LS-13727, SC-04758, ZB006767, 1-(2,4,6-Trihydroxyphenyl)ethanone, 9CI, DB-051513, TC-162712, TR-017649, FT-0601335, FT-0688182, ST50307942, T1888, C21895, M-4121, 2', 4', 6'-Trihydroxyacetophenone Monohydrate, 2'4'6'-TRIHYDROXYACETOPHENONE N-HYDRATE, SR-05000002401, SR-05000002401-1, W-106057, BRD-K64824948-001-02-2, BRD-K64824948-001-03-0, InChI=1/C8H8O4/c1-4(9)8-6(11)2-5(10)3-7(8)12/h2-3,10-12H,1H, 83X

ID: 2602

chemical graph of compound 2602



InChIKey: XLFWDASMENKTKL-UHFFFAOYSA-N
SMILES: CCO/C(=N/C1=C[N+](=NO1)N2CCOCC2)/[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4238
synonyms found at PubChem are:
25717-80-0, Molsidomin, N-(Ethoxycarbonyl)-3-(4-morpholinyl)sydnone imine, AC1L1HPV, CHEBI:31861, CTK8E8012, KS-00001FAH, MolPort-023-220-276, XLFWDASMENKTKL-NTMALXAHSA-N, HMS3369H14, HMS3373B04, AKOS030254869, LP00725, H532, M2524, 1-ethoxy-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)methanimidate, (Z)-5-(ethoxycarbonylimino)-3-morpholino-5H-1,2,3-oxadiazol-3-ium-2-ide, molsidomine, morsydomine, Corvaton, Molsidolat, Motazomin, SIN-10, Sydnopharm, Morial, N-Ethoxycarbonyl-3-morpholinosydnonimine, Molsidominum [INN-Latin], Molsidomina [INN-Spanish], MLS000028573, UNII-D46583G77X, CAS 276, EINECS 247-207-4, BRN 3999414, SMR000058990, Sydnone imine, N-(ethoxycarbonyl)-3-(4-morpholinyl)-, N-Carboxy-3-morpholinosydnonimine ethyl ester, N-Carboxy-3-morpholinosydnone imine ethyl ester, N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine, Corvasal, Coruno, Sydnone imine, N-carboxy-3-morpholino-, ethyl ester, D46583G77X, NCGC00015661-02, CAS-25717-80-0, DSSTox_CID_25171, DSSTox_RID_80721, DSSTox_GSID_45171, Molsidomina, Molsidominum, Covarsal, Korvatone, (1E)-1-ethoxy-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)methanimidate, (1E)-1-ethoxy-N-(3-morpholin-4-yl-1,2,3-oxadiazol-3-ium-5-yl)methanimidate, (1E)-1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate, SR-05000001464, N-Carboxy-3-morpholinosynonimine ethyl ester, Corraton, ethyl (NZ)-N-(3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-ylidene)carbamate, Molsidomine [USAN:BAN:INN:JAN], Molsidomine [USAN:INN:BAN:JAN], Prestwick_863, Opera_ID_238, AC1NS4KW, Prestwick3_000547, Lopac-M-2901, SIN 10 (pharmaceutical), SCHEMBL34019, BSPBio_000593, MLS001146942, MLS002153869, SPECTRUM1500673, Molsidomine (JAN/USAN/INN), BPBio1_000653, CHEMBL1256353, CHEMBL1329455, DTXSID0045171, BDBM39912, CHEBI:92623, cid_5353788, HMS501O05, MolPort-003-666-317, MolPort-005-937-659, MolPort-009-684-981, MolPort-035-394-902, HMS1569N15, HMS1921A16, HMS2089L03, HMS2092G20, HMS2096N15, HMS2232F20, HMS2235B12, HMS3262A12, HMS3649M16, HMS3713N15, HY-B1069, Molsidomine 1.0 mg/ml in Methanol, Tox21_110192, Tox21_500725, CCG-40069, MFCD00869301, s4664, 5-[(Ethoxycarbonyl)amino]-3-(4-morpholinyl)-1,2,3-oxadiazolium Inner Salt, AKOS015843340, AKOS015900360, AKOS015962928, AKOS026749793, Tox21_110192_1, AC-7473, AN-8958, CCG-220547, CS-4625, DB09282, KS-5160, MCULE-1835289527, ACM25717800, NCGC00015661-01, NCGC00015661-03, NCGC00015661-04, NCGC00015661-05, NCGC00015661-06, NCGC00015661-07, NCGC00015661-08, NCGC00015661-09, NCGC00015661-10, NCGC00015661-12, NCGC00024136-03, NCGC00024136-04, NCGC00024136-05, NCGC00024136-06, NCGC00024136-07, NCGC00261410-01, SC-15261, SMR001233224, SBI-0050703.P004, LS-148340, TC-064031, AB00513859, EU-0100725, N-(Ethoxycarbonyl)-3-morpholinosydnone imine, ST51015046, D01320, K-6715, AB00052152_14, AB00513859-02, A817988, I14-0398, SR-05000001464-1, SR-05000001464-3, W-107222, ethoxy-N-(3-morpholin-4-yl(1,2,3-oxadiazol-5-yl))carboxamide, (1E)-1-ethoxy-N-(3-morpholinooxadiazol-3-ium-5-yl)formimidate, (1E)-1-ethoxy-N-(3-morpholinooxadiazol-3-ium-5-yl)methanimidate, Ethyl (3-morpholin-4-yl-1-oxa-2-aza-3-azoniacyclopenta-2,4-dien-5-yl)aminoformate, AC1NSES5, Pharmakon1600-01500673, NSC757398, NSC-757398, NCGC00179510-01, BRD-K35531059-001-02-4, (1Z)-1-ethoxy-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)methanimidate

ID: 2603

chemical graph of compound 2603



InChIKey: XLHIYUYCSMZCCC-VMPITWQZSA-N
SMILES: COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=O)O2)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281575
synonyms found at PubChem are:
Yangonin, 500-62-9, 4-Methoxy-6-(p-methoxystyryl)-2H-pyran-2-one, UNII-R970U49V3C, 4-Methoxy-6-(beta-(p-anisyl)vinyl)-alpha-pyrone, NSC 212502, CHEBI:10089, R970U49V3C, NSC212502, 2H-PYRAN-2-ONE, 4-METHOXY-6-(p-METHOXYSTYRYL)-, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]pyran-2-one, 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic acid gamma-lactone, (E)-4-Methoxy-6-(4-methoxystyryl)-2H-pyran-2-one, 4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-one, 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-, 2H-Pyran-2-one, 4-methoxy-6-(2-(4-methoxyphenyl)ethenyl)-, (E)-, 2H-Pyran-2-one, 4-methoxy-6-[2-(4-methoxyphenyl)ethenyl]-, (E)-, CCRIS 9372, AC1NQYNM, UPCMLD-DP034, DSSTox_CID_14102, DSSTox_RID_79115, DSSTox_GSID_34102, Yangonin, analytical standard, SCHEMBL1393965, CHEMBL1098658, DTXSID4034102, UPCMLD-DP034:001, UPCMLD-DP034:002, MolPort-006-069-437, XLHIYUYCSMZCCC-VMPITWQZSA-N, ZINC899671, HY-N0919, Tox21_202547, 8290AH, ACM500629, NSC112160, AKOS022184639, CCG-208617, NSC-112160, NSC-212502, NCGC00091909-01, NCGC00091909-03, NCGC00260096-01, 4-Methoxy-6-(4-methoxystyryl)-a-pyrone, AJ-24290, AN-45356, CAS-500-62-9, ZB015165, 6-(p-Methoxystyryl)-4-methoxy-|A-pyrone, LS-127463, 4-Methoxy-6-[|A-(p-anisyl)vinyl]-|A-pyrone, C09980, 500Y629, A827952, SR-05000002174, SR-05000002174-2, 4-Methoxy-6-(.beta.-(p-anisyl)vinyl)-.alpha.-pyrone, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-2-pyranone, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]pyran-2-one, 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one, 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one, 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one #, 4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one, 9CI, 2H-Pyran-2-one, 4-methoxy-6-(2-(4-methoxyphenyl)ethenyl)-, (E)- (9CI), 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic acid .gamma.-lactone

ID: 2604

chemical graph of compound 2604



InChIKey: XLMALTXPSGQGBX-PGRDOPGGSA-N
SMILES: CCC(=O)O[C@@](CC1=CC=CC=C1)(C2=CC=CC=C2)[C@@H](C)CN(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 200742
synonyms found at PubChem are:
Levopropoxyphene, l-Propoxyphene, (-)-Propoxyphene, Levopropoxifeno, Levopropossifene, Levopropoxyphenum, 2338-37-6, UNII-U75VZ9PK1J, (l)-Propoxyphene, U75VZ9PK1J, Levopropoxiphenum, Levopropossifene [DCIT], Levopropoxyphene [INN:BAN], Levopropoxifeno [INN-Spanish], Levopropoxyphenum [INN-Latin], HSDB 3414, Levo-Propoxyphene, (-)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-(propionyloxy)butane, (R)-alpha-(2-(Dimethylamino)-1-methylethyl)-alpha-phenylbenzeneethanol propanoate, USAF EL-84, alpha-L-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate, 2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate (ester), (-)-, AC1L44ZJ, SCHEMBL158770, 1-Benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propionate #, CHEMBL1738990, DTXSID8023212, CHEBI:51174, XLMALTXPSGQGBX-PGRDOPGGSA-N, Benzeneethanol, alpha-((1S)-2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (alphaR)-, Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (R-(R*,S*))-, Methanol, compd. with (+-)-alpha-(2-dimethylamino)-1-methylethyl-alpha- phenylphenethyl propionate (1:1), ZINC1530767, DB06793, LS-91022, UNII-II2G62OV6F component XLMALTXPSGQGBX-PGRDOPGGSA-N, Benzeneethanol, a-[(1S)-2-(dimethylamino)-1-methylethyl]-a-p, [4-(dimethylamino)-3-methyl-1,2-di(phenyl)butan-2-yl] propanoate, (1R,2S)-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate, [(2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate, [(2R,3S)-4-dimethylamino-3-methyl-1,2-diphenyl-butan-2-yl]propanoate, (1R,2S)-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate

ID: 2605

chemical graph of compound 2605



InChIKey: XLOPRKKSAJMMEW-UHFFFAOYSA-N
SMILES: CC(=CC1C(C1(C)C)C(=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2743
synonyms found at PubChem are:
CHRYSANTHEMIC ACID, 10453-89-1, Chrysanthemumic acid, Chrysanthemummonocarboxylic acid, D,L-cis,trans-Chrysanthemic acid, NSC 11779, CCRIS 2496, 3-Isobutenyl-2,2-dimethylcyclopropanecarboxylic acid, 2-(1-Isobutenyl)-3,3-dimethylcyclopropanecarboxylic acid, EINECS 233-941-2, BRN 2043418, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, AI3-20453, CHEBI:3680, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, XLOPRKKSAJMMEW-UHFFFAOYSA-N, 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid, NSC11779, Chrysanthemic acid (cis/trans=1:10), 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)Cyclopropanecarboxylic acid, 2,2-Dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid, Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylic acid, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 4638-92-0, 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylic acid, Chrysamthemic acid, Chrysanthemumsaeure, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1R,3R)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1R,3S)-rel-, 2935-23-1, Spectrum_001622, SpecPlus_000441, AC1Q5TCW, Spectrum2_001682, Spectrum3_001926, Spectrum4_001755, Spectrum5_000610, AC1L1ED8, AC1Q2A1N, DL-CHRYSANTHEMIC ACID, SCHEMBL62874, BSPBio_003526, KBioGR_002230, KBioSS_002102, 2-09-00-00047 (Beilstein Handbook Reference), DivK1c_006537, SPECTRUM1504800, SPBio_001604, (.+-.)-Chrysanthemumic acid, Jsp000445, (.+/-.)-Chrysanthemumic acid, CHEMBL1437285, CTK0H6267, KBio1_001481, KBio2_002102, KBio2_004670, KBio2_007238, KBio3_002752, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1R,3R)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1R,3R)-rel-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1R,3S)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1R,3S)-rel-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1S,3R)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, (1S,3S)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1R,3R)-rel-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1R,3S)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1S,3R)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1S,3S)-, MolPort-001-785-569, CCG-38773, NSC-11779, STL182755, AKOS001204877, AKOS016042366, MCULE-4506773274, NE36766, SDCCGMLS-0066800.P001, NCGC00094564-01, NCGC00094564-02, NCGC00094564-03, AS-16143, LS-58668, LS-58669, NCI60_000424, S677, SC-51014, WLN: L3TJ A1 A1 BVQ C1UY1&1, FT-0657800, FT-0705410, chrysanthemum monocarboxylic acid mixed isomers, EN300-24002, Chrysanthemic acid 10 microg/mL in Cyclohexane, SR-05000002402, SR-05000002402-1, W-108810, BRD-A52893269-001-02-4, BRD-A52893269-001-03-2, Cyclopropanecarboxylic acid,2-dimethyl-3-(2-methylpropenyl)-, 3- (2-methyl-1-propenyl) -2, 2-dimethylcyclopropanecarboxylic acid, 3-(2-methyl-1-propenyl)-2,2-dimethylcyclopropanecarboxylic acid, 3-(2-methylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid, Cyclopropanecarboxylic acid,2-dimethyl-3-(2-methyl-1-propenyl)-, 30636-83-0, 497-68-7

ID: 2606

chemical graph of compound 2606



InChIKey: XLRKFSDSKCYZBE-ASGOMDNQSA-N
SMILES: C[C@@]12CCC3=C(C1=CC(=O)O[C@H]2C4=COC=C4)C[C@H]5C(=O)C([C@@H](C3(C5=O)C)CC(=O)OC)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6857744
synonyms found at PubChem are:
SPECTRUM100102, CCG-39813, SDCCGMLS-0066295.P001

ID: 2607

chemical graph of compound 2607



InChIKey: XLTFNNCXVBYBSX-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281703
synonyms found at PubChem are:
Wogonin, 632-85-9, 5,7-Dihydroxy-8-methoxyflavone, Vogonin, Norwogonin 8-methyl ether, UNII-POK93PO28W, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-methoxy-2-phenyl-, BRN 0287152, POK93PO28W, 5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one, CHEMBL16171, FLAVONE, 5,7-DIHYDROXY-8-METHOXY-, CHEBI:10043, 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one, XLTFNNCXVBYBSX-UHFFFAOYSA-N, 5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one, ST077088, Q-100730, 4H-1-Benzopyran-4-one,5,7-dihydroxy-8-methoxy-2-phenyl-, 5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one, wagonin, Wogonin,(S), AC1NQYXJ, D00MXS, MLS002473006, SCHEMBL139083, CTK5B8471, DTXSID70212557, MolPort-001-742-489, HMS2270G08, ZINC899093, HY-N0400, BDBM50140257, BN0711, GP7400, IN1943, LMPK12111330, MFCD12828871, NSC717845, s4743, AKOS015917860, ZINC111327191, CCG-208499, CS-3959, MCULE-9854289767, NSC-717845, NCGC00247464-01, 4CN-1056, AC-20338, AN-46964, LS-68974, NCI60_040649, SC-25044, SMR001397111, ZB015158, TR-021802, FT-0603499, N1283, V1530, C10197, 632W859, C-17890, SR-05000002216, I14-8669, SR-05000002216-2, 5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one(Wogonin)

ID: 2608

chemical graph of compound 2608



InChIKey: XLWJPQQFJNGUPA-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC(C)(C)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5024764
synonyms found at PubChem are:
CGP-7930, CGP 7930, CGP7930, 57717-80-3, CHEMBL1256697, XLWJPQQFJNGUPA-UHFFFAOYSA-N, 2,6-ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol, 3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol, 28-99-9, SR-01000075738, Tocris-1513, AC1NNCN1, Lopac-C-0862, Lopac0_000169, MLS002153413, GTPL1079, SCHEMBL2371710, CHEBI:93152, 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol, DTXSID90407620, MolPort-003-940-608, HMS2230F05, HMS3260B19, HMS3268A09, HMS3370F06, ZINC2526560, Tox21_500169, ABP001026, BDBM50108996, BN0128, AKOS024456641, API0007845, CCG-204264, LP00169, NCGC00015210-01, NCGC00015210-02, NCGC00015210-03, NCGC00015210-04, NCGC00015210-05, NCGC00025198-01, NCGC00025198-02, NCGC00025198-03, NCGC00260854-01, SMR001230789, CGP-7930, >98% (HPLC), solid, LS-193044, EU-0100169, C 0862, SR-01000075738-1, SR-01000075738-3, BRD-K65786282-001-02-6, 2,2-di-methyl-3-(3,5-di-t-butyl-4-hydroxyphenyl)propanol, 3-(3,5-di-t-butyl-4-hydroxyphenyl)-2,2-dimethylpropanol, 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-?,?-dimethyl-benzenepropanol, 3-(3 inverted exclamation marka,5 inverted exclamation marka-Di-tert-butyl-4 inverted exclamation marka-hydroxy)phenyl-2,2-dimethylpropanol

ID: 2609

chemical graph of compound 2609



InChIKey: XMFCOYRWYYXZMY-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)S(=O)C)C2=NC3=C(N2)C=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5353
synonyms found at PubChem are:
sulmazole, sulmazol, 73384-60-8, Vardax, Sulmazolum, Sulmazole [INN], Sulmazol [INN-Spanish], Sulmazolum [INN-Latin], AR-L 115BS, AR-L 115 BS, AR-L 115-BS, EINECS 277-406-1, 2-[2-methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-b]pyridine, BRN 0818370, CHEMBL286020, CHEBI:34988, NCGC00016924-02, 2-(2-Methoxy-4-(methylsulfinyl)phenyl)-1H-imidazo(4,5-b)pyridine, 2-(2-Methoxy-4-(methylsulfinyl)phenyl)-3H-imidazo[4,5-b]pyridine, CAS-73384-60-8, 1H-Imidazo(4,5-b)pyridine, 2-(2-methoxy-4-(methylsulfinyl)phenyl)-, 2-(2-Methoxy-4-(methylsulfinyl)phenyl)-3H-imidazo(4,5-b)pyridine, 2-[2-methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine, SR-01000841215, BWA746C, 2-(2-methoxy-4-(methylsulfinyl)phenyl)-1H-imidazo[4,5-b]pyridine, BW A746C, AR-L115, Prestwick_1012, Spectrum_001155, LY175326, MG 28734, MG-28734, Prestwick0_000641, Prestwick1_000641, Prestwick2_000641, Prestwick3_000641, Spectrum3_000733, Spectrum4_001246, Spectrum5_002074, AC1L1K5W, AC1Q6YK1, DSSTox_CID_20617, DSSTox_RID_79513, DSSTox_GSID_40617, BSPBio_000641, BSPBio_002286, KBioGR_001772, KBioSS_001635, MLS002153927, DivK1c_000276, SCHEMBL187165, SPECTRUM1501159, SPBio_002562, BPBio1_000707, DTXSID1040617, AR-L-115-BS, CTK5D7914, CTK9A2962, HMS500N18, KBio1_000276, KBio2_001635, KBio2_004203, KBio2_006771, KBio3_001506, NINDS_000276, XMFCOYRWYYXZMY-UHFFFAOYSA-N, HMS1570A03, HMS2097A03, HMS2230O09, HMS3371L17, HMS3714A03, Pharmakon1600-01501159, 2-((2-methoxy-4-methylsulfinyl)phenyl)-H-imidazo(4,5-b)pyridine, Tox21_110685, 2-[2-methoxy-4-(methylsulfinyl)phenyl]-4h-imidazo[4,5-b]pyridine, BDBM50000056, CCG-38446, NSC757867, AKOS022185317, API0008357, CCG-220641, NSC-757867, IDI1_000276, NCGC00016924-01, NCGC00095999-01, DA-03824, LS-80285, SMR001233271, SBI-0051668.P002, AB00052230, FT-0748740, C13749, SR-01000841215-2, SR-01000841215-3, BRD-A22081593-001-04-6, BRD-A22081593-001-06-1, 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo[4,5-b]pyridine, 2-(2-methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine, 2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine, 2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine, 2-Methyl-6-oxo-1,6-dihydro-[3,4'']bipyridinyl-5-carbonitrile, 3H-Imidazo[4,5-b]pyridine,2-[2-methoxy-4-(methylsulfinyl)phenyl]-, (sulmazole)2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine, 2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine (sulmazole), 2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine(sulmazole), 112363-11-8

ID: 2610

chemical graph of compound 2610



InChIKey: XMOCLSLCDHWDHP-UHFFFAOYSA-N
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O

biological descriptors:

CFTR relevance: no effect

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"L Chen" "T Ma" "H Yang" "X Gao" "B Yu" "L Zhu" "Y Zhang"


CID is 1249
synonyms found at PubChem are:
CHEBI:71224, 2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, (-)EPIGALLOCATECHIN, NSC674038, NSC674039, (-)-3,5,7,3',4',5'-Hexahydroxylflavan, AC1L1B1Z, AC1Q79WI, CHEMBL404845, SCHEMBL1972940, CTK8D5887, (2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, 13425-13-3, AKOS032947774, flavan-3,3',4',5,5',7-hexol, 3,3',4',5,5',7-Hexahydroxyflavan, 3,5,7,3',4',5'-Hexahydroxyflavan, NCGC00095541-01, 4CH-024112, 2-(3,4,5-trihydroxyphenyl)chromane-3,5,7-triol, 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman, CCD3AC6F-06C0-43D8-94C8-58130D45DFA9, 2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-

ID: 2611

chemical graph of compound 2611



InChIKey: XMTQQYYKAHVGBJ-UHFFFAOYSA-N
SMILES: CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3120
synonyms found at PubChem are:
diuron, 3-(3,4-Dichlorophenyl)-1,1-dimethylurea, 330-54-1, DCMU, Duran, Dynex, Dichlorfenidim, Herbatox, Vonduron, Dailon, Karmex, Marmer, Karmex DW, Di-on, Cekiuron, Crisuron, Lucenit, Unidron, Diuron Nortox, Karmex D, Karmex Diuron Herbicide, 1-(3,4-Dichlorophenyl)-3,3-dimethylurea, Preventol A 6, Urox D, Diuron 4L, Direx 4L, DP Hardener 95, Telvar Diuron Weed Killer, Urea, N'-(3,4-dichlorophenyl)-N,N-dimethyl-, 1,1-Dimethyl-3-(3,4-dichlorophenyl)urea, Anduron, Ansaron, Dirurol, Durashield, Herburon, Seduron, Bioron, Drexel, Farmco diuron, Sup'r flo, N'-(3,4-Dichlorophenyl)-N,N-dimethylurea, DCMU 99, Diuron 900, Caswell No. 410, HW 920, Ditox-800, N-(3,4-Dichlorophenyl)-N',N'-dimethylurea, Karamex, Aguron, Diater, Dichlorfenidim [Russian], UNII-9I3SDS92WY, USAF P-7, Diuron [ANSI:BSI:ISO], N,N,-Dimethyl-N'-(3,4-dichlorophenyl)urea, USAF XR-42, 3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff, CCRIS 1012, HSDB 382, Direx 80W, 1-(3,4-Dichlorophenyl)-3,3-dimethyluree, NSC 8950, EINECS 206-354-4, AF 101, Urea, 3-(3,4-dichlorophenyl)-1,1-dimethyl-, EPA Pesticide Chemical Code 035505, BRN 2215168, 9I3SDS92WY, AI3-61438, 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, 3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea, 3-(3,4-Dichloor-fenyl)-1,1-dimethylureum, CHEBI:116509, XMTQQYYKAHVGBJ-UHFFFAOYSA-N, 1-(3,4-Dichlorophenyl)-3,3-dimethyluree [French], 3-(3,4-Dichloor-fenyl)-1,1-dimethylureum [Dutch], 3-(3,4-Dicloro-fenyl)-1,1-dimetil-urea [Italian], 3-(3,4-Dichlor-phenyl)-1,1-dimethyl-harnstoff [German], NCGC00094525-01, N-(3,4-Dichlorophenyl)-N,N-Dimethylurea, DSSTox_CID_446, 3-(3,4-Dichloro-phenyl)-1,1-dimethyl-urea, DSSTox_RID_75595, DSSTox_GSID_20446, CAS-330-54-1, Xarmex, Diuron solution, Xarmex, Krovar, M Velpar, Karmex DL, D rexel diuron 4L, Karmex 80W, Spectrum_001823, 1-(3,3-dimethylurea, 3-(3,1-dimethylurea, ACMC-1CQJF, SpecPlus_000424, N'-(3,N-dimethylurea, N-(3,N'-dimethylurea, 1,4-dichlorophenyl)urea, 3-(3,1-dimethylureum, n,n-dimethyl-n'-(3,4-dichlorophenyl)urea, 3-(3,1-dimetil-urea, Spectrum2_001229, Spectrum3_000822, Spectrum4_000662, Spectrum5_001956, Diuron, >=98%, EC 206-354-4, AC1L1F7Q, AC1Q3W1I, AC1Q3W1S, Cambridge id 5104305, SCHEMBL7279, 3-(3,1-dimethyl-harnstoff, BSPBio_002343, KBioGR_001063, KBioSS_002328, SPECTRUM330030, MLS002207110, DivK1c_006520, SPBio_001078, CHEMBL278489, URE002, DTXSID0020446, CTK7G2120, KBio1_001464, KBio2_002325, KBio2_004893, KBio2_007461, KBio3_001843, ZINC57287, NSC8950, MolPort-001-837-578, WLN: GR BG DMVN1 & 1, NSC-8950, Tox21_111292, Tox21_201438, Tox21_301016, ANW-27531, BBL003847, CCG-39151, Diuron 10 microg/mL in Acetonitrile, MFCD00018136, STK077954, AKOS001303464, Diuron 100 microg/mL in Acetonitrile, Tox21_111292_1, Urea,4-dichlorophenyl)-N,N-dimethyl-, LS-7325, MCULE-1921281405, RTR-013860, Urea,4-dichlorophenyl)-1,1-dimethyl-, KS-0000105P, NCGC00094525-02, NCGC00094525-03, NCGC00094525-04, NCGC00094525-05, NCGC00094525-06, NCGC00094525-07, NCGC00094525-08, NCGC00094525-09, NCGC00254918-01, NCGC00258989-01, AN-44343, AS-15493, P597, SMR000777941, ZB002067, Diuron, PESTANAL(R), analytical standard, 3-(3,4-Dichlorophenol)-1,1-dimethylurea, Diuron solution 100 ng/muL in acetonitrile, KB-177516, TR-013860, D1328, FT-0603378, N,N-dimethyl-N'-(3,4-dichlorophenyl)-urea, ST50409103, T7706, N-(3,4-dichlorophenyl)-N',N'-dimethyl urea, C18428, 33329-EP2274983A1, 33329-EP2305655A2, 33329-EP2305662A1, 33329-EP2311815A1, 33329-EP2371823A1, N-(3,4-dichlorophenyl)(dimethylamino)carboxamide, A821585, SR-01000195223, Diuron, certified reference material, TraceCERT(R), I01-4399, J-018992, SR-01000195223-1, BRD-K75330923-001-02-6, Diuron solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 102962-29-8, 127641-75-2, 150825-44-8, 201749-62-4, 56449-18-4, W9M

ID: 2612

chemical graph of compound 2612



InChIKey: XMVJITFPVVRMHC-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1[As](=O)(O)O)[N+](=O)[O-])O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5104
synonyms found at PubChem are:
roxarsone, 121-19-7, Ristat, 4-Hydroxy-3-nitrobenzenearsonic acid, 3-Nitro, 4-Hydroxy-3-nitrophenylarsonic acid, Aklomix-3, Roxarson, Ren-O-sal, 3-Nitro-10, 3N4hpa, Nitrophenolarsonic acid, Roxarsonum, 3-Nitro-20, 3-Nitro-50, 3-Nitro-80, Ren O-sal, 3-NITRO-4-HYDROXYPHENYLARSONIC ACID, (4-hydroxy-3-nitrophenyl)arsonic acid, 3-Nitro-4-hydroxybenzenearsonic acid, Arsonic acid, (4-hydroxy-3-nitrophenyl)-, NCI-C56508, 2-Nitro-1-hydroxybenzene-4-arsonic acid, NIH 1529, NSC-2101, C6H6AsNO6, Nitro acid 100 per cent, 2-Nitrophenol-4-arsonic acid, Roxarson [INN-Spanish], Roxarsonum [INN-Latin], Benzenearsonic acid, 4-hydroxy-3-nitro-, UNII-H5GU9YQL7L, A 19603, NSC 2101, Roxarsone [USAN:INN:BAN], CCRIS 1661, HSDB 4296, nitrophenoloarsonic acid, Roxarsone (USP/INN), 4-Hydroxy-3-nitrobenzolarsonsaeure, EINECS 204-453-7, H5GU9YQL7L, BRN 1976533, Kyselina 4-hydroxy-3-nitrofenylarsonova, AI3-16421, Arsonic acid, As-(4-hydroxy-3-nitrophenyl)-, CHEBI:35817, NSC2101, Kyselina 4-hydroxy-3-nitrofenylarsonova [Czech], 4-hydroxy-3-nitrophenyl arsonic acid, (4-hydroxy-3-nitro-phenyl)arsonic acid, NCGC00016372-01, CAS-121-19-7, DSSTox_CID_956, 4-HYDROXY-3-NITRO-BENZENEARSONIC ACID, DSSTox_RID_75884, DSSTox_GSID_20956, SR-05000001714, Roxarsone(usan), Roxarsone [USAN:USP:INN:BAN], Spectrum_000942, AC1L1JMC, Prestwick0_000970, Prestwick1_000970, Prestwick2_000970, Prestwick3_000970, Spectrum2_000479, Spectrum3_000566, Spectrum4_000498, Spectrum5_001658, ACMC-209a9k, component of 3-Nitro-10, component of 3-Nitro-20, component of 3-Nitro-50, component of 3-Nitro-80, BSPBio_000979, BSPBio_001952, KBioGR_001015, KBioSS_001422, 4-16-00-01188 (Beilstein Handbook Reference), KSC496K2B, MLS002154078, DivK1c_000500, SCHEMBL158026, SPECTRUM1500530, SPBio_000618, SPBio_002900, WLN: WNR BQ E-AS-QQO, 2-Nitrophenolarsonic acid-(4), BPBio1_001077, Roxarsone, BAN, INN, USAN, CHEMBL1321154, DTXSID9020956, CTK3J6520, HMS501I22, KBio1_000500, KBio2_001422, KBio2_003990, KBio2_006558, KBio3_001452, KS-00000YZE, XMVJITFPVVRMHC-UHFFFAOYSA-, component of Polystat (Salt/Mix), MolPort-001-783-084, NINDS_000500, XMVJITFPVVRMHC-UHFFFAOYSA-N, HMS1571A21, HMS1920P10, HMS2092G11, HMS2098A21, HMS2234I16, HMS3374C10, Pharmakon1600-01500530, HY-B0936, component of Unistat-3 (Salt/Mix), Tox21_110402, Tox21_201465, Tox21_302842, ANW-17574, CCG-39723, LS-643, NSC757312, 3-Nitro-4-hydroxyphenyl arsonic acid, 4-hydroxy-3-nitrobenzenenearsonic acid, AKOS015960757, component of 3-Nitro-10 (Salt/Mix), component of 3-Nitro-50 (Salt/Mix), component of 3-Nitro-80 (Salt/Mix), Tox21_110402_1, NSC-757312, RTR-003472, (4-Hydroxy-3-nitrobenzene)arsonic acid, (4-hydroxy-3-nitrophenyl)-Arsonic acid, 3-nitro-4-hydroxy-1-phenylarsonic acid, IDI1_000500, (3-nitro-4-oxidanyl-phenyl)arsonic acid, NCGC00016372-02, NCGC00016372-03, NCGC00016372-04, NCGC00016372-07, NCGC00094778-01, NCGC00094778-02, NCGC00256417-01, NCGC00259016-01, AN-43379, S044, SMR001233388, SBI-0051507.P003, As-(4-hydroxy-3-nitrophenyl)-Arsonic acid, TR-003472, AB00052087, FT-0616222, Roxarsone, VETRANAL(TM), analytical standard, D05771, AB00052087_07, A804687, C-30923, J-004458, SR-05000001714-1, SR-05000001714-3, I14-100421, Roxarsone, United States Pharmacopeia (USP) Reference Standard, 8028-22-6, 8028-23-7, InChI=1/C6H6AsNO6/c9-6-2-1-4(7(10,11)12)3-5(6)8(13)14/h1-3,9H,(H2,10,11,12)

ID: 2613

chemical graph of compound 2613



InChIKey: XNEFYCZVKIDDMS-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 51040
synonyms found at PubChem are:
Avobenzone, 70356-09-1, Parsol 1789, Butyl methoxydibenzoylmethane, Photoplex, 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione, 4-tert-Butyl-4'-methoxy-dibenzoylmethane, Escalol 517, Eusolex 9020, UNII-G63QQF2NOX, Avobenzonum [INN-Latin], butylmethoxydibenzoylmethane, Avobenzona [INN-Spanish], 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)-1,3-propanedione, HSDB 7423, 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-, EINECS 274-581-6, 4-TERT-BUTYL-4'-METHOXYDIBENZOYLMETHANE, G63QQF2NOX, 1-(4-(tert-Butyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione, 1-(p-tert-Butylphenyl)-3-(p-methoxyphenyl)-1,3-propanedione, XNEFYCZVKIDDMS-UHFFFAOYSA-N, 87075-14-7, NCGC00095112-01, 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)-1,3-propanedione, 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione, DSSTox_CID_24829, DSSTox_RID_80510, DSSTox_GSID_44829, Q-200661, Avobenzona, Avobenzonum, 1,3-Propanedione, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)-, 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedi- one, 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione, Parsol A, SMR001562107, CAS-70356-09-1, Avobenzone [USAN:INN], Avobenzone [USAN:USP:INN], avobenzone(usp), 4-t-butyl-4'-methoxy-dibenzoylmethane, Spectrum_001715, SpecPlus_000764, Avobenzone (USP/INN), AC1L1ABS, Spectrum2_001663, Spectrum3_000990, Spectrum4_001116, Spectrum5_001358, ACMC-209oe7, Avobenzone(Parsol 1789), EC 274-581-6, AC1Q5DT1, Avobenzone (Parsol 1789), SCHEMBL15650, BSPBio_002659, KBioGR_001592, KBioSS_002195, ZINC973, MLS002695918, MLS006010050, BIDD:ER0196, DivK1c_006860, SPECTRUM1504190, Avobenzone ; 4-t-butyl-4'-methoxy-dibenzoylmethane, SPBio_001845, Avobenzone, analytical standard, CHEMBL1200522, DTXSID9044829, CTK3J0255, KBio1_001804, KBio2_002195, KBio2_004763, KBio2_007331, KBio3_001879, CHEBI:134751, MolPort-003-666-540, HMS1922F17, HMS2093C04, HMS3655C22, HMS3715F14, Pharmakon1600-01504190, HY-B0316, Tox21_111427, Tox21_202796, ANW-35885, CCG-39080, NSC758680, s1904, AKOS015838120, Tox21_111427_1, AC-1682, AS04672, CS-2356, DB09495, NSC-758680, RL04694, KS-000000A0, NCGC00095112-02, NCGC00095112-03, NCGC00095112-04, NCGC00095112-05, NCGC00260342-01, AK-48454, AN-14673, AS-12797, BC215936, OR350370, SBI-0052777.P002, AB2000363, KB-215018, LS-170014, ST2414995, TC-124630, B3382, FT-0623334, D03015, AB00053273_04, AB00053273_05, A836855, SR-05000001974, I01-2051, SR-05000001974-1, Eusolex 9020;Escalol 517;Parsol 1789;Parsol 1789, 1-(4-methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione, 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)-propane-1,3-dione, Avobenzone, United States Pharmacopeia (USP) Reference Standard, Avobenzone, Pharmaceutical Secondary Standard; Certified Reference Material, 185160-18-3

ID: 2614

chemical graph of compound 2614



InChIKey: XNKLLVCARDGLGL-JGVFFNPUSA-N
SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 18283
synonyms found at PubChem are:
stavudine, sanilvudine, 3056-17-5, Zerit, 2',3'-Didehydro-3'-deoxythymidine, Estavudina, Stavudinum, Zerit Xr, Zerut XR, Stavudinum [INN-Latin], 2',3'-Anhydrothymidine, Estavudina [INN-Spanish], BMY-27857, d4T, ddeThd, D 4T (nucleoside), Thymidine, 2',3'-didehydro-3'-deoxy-, BMY 27857, 3'-Deoxy-2'-thymidinene, 2',3'-Didehydro-3'-deoxythimidine, Stavudine [USAN:BAN:INN], D 4T, Dideoxydidehydrothymidine, ddeTyd, UNII-BO9LE4QFZF, Zent, 3'-Deoxy-2',3'-didehydrothymidine, Stavudine [USAN:INN:BAN], Zerit(TM), 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine, Sanilvudine (JAN), Zerit (TN), HSDB 7338, BO9LE4QFZF, Stavudine (USAN/INN), CHEMBL991, NSC 163661, BRN 0618327, D4T & GM-CSF, 2'-Thymidinene, 3'-deoxy-, 1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, MLS000028546, STV, CHEBI:63581, XNKLLVCARDGLGL-JGVFFNPUSA-N, D4TMBY-27857-3, 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione, 1-[(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL]-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE, NCGC00023212-07, SMR000058350, DSSTox_CID_3819, D 1413, 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione, DSSTox_RID_77198, DSSTox_GSID_23819, 2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE (DDI), 1-(2,3-Dideoxy-beta-D-glycero-2-pentenofuranosyl)thymine, Stavudine (d4T), Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)- (7CI,8CI), 1-((2R,5S)-5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-[5-(hydroxymethyl)-2,5-dihydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione & Colony-stimulating factor 2, CAS-3056-17-5, SR-01000075802, Stavudine, Monosodium Salt, staduvine, Stavudin, NSC163661, Stavudine [USAN:USP:INN:BAN], BMY27857, 2',3' Didehydro 3' deoxythymidine, PubChem5805, 2',3'-Didehydro-2',3'-dideoxythmidine, AC1Q6BSH, Opera_ID_1281, 3'-deoxythymidin-2'-ene, D0Z8EX, AC1L2BQ9, cid_5155, 3''-deoxy-2''-thymidine, Lopac0_000336, SCHEMBL38661, cid_18283, MLS000759504, MLS001055348, MLS001077292, MLS001424091, MLS006011922, BIDD:GT0082, 2',3'-Anhydrothymidine; d4T, DTXSID1023819, Bristol-Myers Brand of Stavudine, CTK8B1419, MolPort-002-507-283, HMS2051O20, HMS2234C10, HMS3039O05, HMS3259L21, HMS3261C13, HMS3428C07, HMS3714N22, Pharmakon1600-01502339, ZINC137884, BCP02952, HY-B0116, Tox21_110886, Tox21_201393, Tox21_300583, Tox21_500336, ABP000995, ANW-26914, BBL033763, BDBM50013111, MFCD00132921, NSC759897, STK801888, 2',3'-Didehydro-3'-deoxy-thymidine, AKOS005622554, Tox21_110886_1, AC-5263, AN-7246, CCG-100902, CS-1872, DB00649, KS-1115, LP00336, LS-1160, MCULE-9252477726, NC00152, NC00684, NSC-759897, RP07238, Bristol-Myers Squibb Brand of Stavudine, KS-00000H34, 2'',3''-didehydro-3''-deoxythymidine, 3''-deoxy-2'',3''-didehydrothymidine, 3'-Deoxy-2',3'-didehydro-D-thymidine, NCGC00023212-03, NCGC00023212-04, NCGC00023212-05, NCGC00023212-08, NCGC00023212-09, NCGC00023212-10, NCGC00023212-11, NCGC00023212-12, NCGC00023212-13, NCGC00023212-14, NCGC00254372-01, NCGC00258944-01, NCGC00261021-01, AJ-12338, BC203877, BR-77340, CPD000058350, CPD000673569, H940, SAM001246729, SAM002589948, SC-03292, SMR000673569, ZB004848, 2',3'-didehydro-2',3'-dideoxythymidine, AB0013374, AB1009564, Thymidine, 2',3'-didehydro-, 3'-deoxy-, D3580, EU-0100336, FT-0082665, FT-0603625, 2'',3''-dideoxy-2'',3''-didehydrothymidine, C07312, D00445, J10003, S-2155, AB00383018_18, 056S175, A820433, J-700246, Q-201742, SR-01000075802-1, SR-01000075802-4, 2',3'-Didehydro-3'-deoxythymidine, >=98% (TLC), Z1695906749, Stavudine, European Pharmacopoeia (EP) Reference Standard, 1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine, Stavudine, United States Pharmacopeia (USP) Reference Standard, Thymine, 1-(2,3-dideoxy-beta-D-glycero-pent-2-enofuranosyl)-(7CI,8CI), 1-(5-Hydroxymethyl-2,5-dihydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (ddeThd), 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione, 3'- Azido-3'-deoxythymidine & Granulocyte-macrophage colony-stimulating factor, Stavudine for system suitability, European Pharmacopoeia (EP) Reference Standard, 1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione, 132425-31-1

ID: 2615

chemical graph of compound 2615



InChIKey: XNXVOSBNFZWHBV-UHFFFAOYSA-N
SMILES: CON.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 521874
synonyms found at PubChem are:
593-56-6, O-METHYLHYDROXYLAMINE HYDROCHLORIDE, Methoxyamine hydrochloride, Methoxylamine hydrochloride, Methoxyammonium chloride, O-METHYLHYDROXYLAMINE HCl, (aminooxy)methane hydrochloride, methoxyamine HCl, UNII-203546OLMF, Hydroxylamine, O-methyl-, hydrochloride, CH6ClNO, O-Methylhydroxyamine hydrochloride, Methoxylammonium Chloride, Hydroxylamine methyl ether hydrochloride, Methyloxyammonium chloride, Methoxyamine, hydrochloride, Hydroxylamine, O-methyl-, hydrochloride (1:1), 203546OLMF, O-methyl hydroxylamine hydrochloride, CCRIS 4846, NSC 3801, EINECS 209-798-7, W-105326, AI3-52923, N-Methoxylamine hydrochloride, methoxylamine-hcl, methoxylamine HCl, MeONH2HCl, N-methoxy amine HCl, methoxyamine HCl salt, MeONH2-HCl, MeONH2.HCl, NH2OMe HCl, NH2OMe-HCl, NH2OMe.HCl, CH3ONH2HCl, methoxyaminehydrochloride, methoxylaminehydrochloride, CH3ONH2.HCl, NH2OCH3.HCl, AC1LAW6S, methoxylamine-hydrochloride, methyoxyamine hydrochloride, O-Methylhydroxylamine, HCl, EC 209-798-7, methoxyl amine hydrochloride, Methoxyl-amine hydrochloride, methoxylamine, hydrochloride, N-methoxyamine hydrochloride, O-Methyl Hydroxylamine HCl, methoxy-amine hydro-chloride, N-methoxy amine hydrochloride, KSC491E2B, 67-62-9 (Parent), methoxyamine hydrochloride salt, methoxylamine hydrogen chloride, SPECTRUM1503970, methoxy amine hydrogen chloride, O-methylhydroxylamine HCl salt, methoxylamine hydrochloride salt, methoxy amine hydrochloride salt, CHEMBL1609430, DTXSID9025615, hydroxymethyltransferase inhibitor, methoxyl amine hydrochloride salt, CTK3J1220, Methoxyamine hydrochloride, 98%, NSC3801, MolPort-001-759-983, o-methylhydroxylamine-hydrochloride, XNXVOSBNFZWHBV-UHFFFAOYSA-N, methoxyamine hydrochloric acid salt, O-methyl hydroxyamine hydrochloride, ACT02829, EBD51935, KS-000000EX, NSC-3801, O-methyl-hydroxylamine hydrochloride, o-methyl-hydroxylamine-hydrochloride, ZX-AT006504, AN-048, ANW-46168, CCG-39625, MFCD00012951, O-methyl hydroxyl amine hydrochloride, O-methyl-hydroxylamine, hydrochloride, AKOS015894265, O-methylhydroxylamine hydrogen chloride, O-methylhydroxylamine monohydrochloride, AC-5593, AM90382, CHM0030339, CS-W020192, MCULE-8687558307, OR18305, RP18076, TRA0026390, NCGC00095839-01, BR-44710, CC-30280, KB-59295, Methoxyamine hydrochloride, bottle of 5 g, SC-18435, AB0008309, AB1004035, AX8034230, DB-053371, O-methylhydroxylamine hydrochloric acid salt, TC-134913, FT-0628308, M0343, M0886, AZ0001-0209, 93M566, Y-9050, A832282, C-00062, I05-0018, F2158-1506, Methoxylamine hydrochloride solution, 25-30 wt. % in H2O, O-Methylhydroxylamine hydrochloride; Methoxylamine hydrochloride, 253880-85-2, 400605-40-5, 73151-12-9, Methoxylamine hydrochloride, 98% 5g

ID: 2616

chemical graph of compound 2616



InChIKey: XOAAWQZATWQOTB-UHFFFAOYSA-N
SMILES: C(CS(=O)(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1123
synonyms found at PubChem are:
taurine, 2-aminoethanesulfonic acid, 107-35-7, L-Taurine, tauphon, Ethanesulfonic acid, 2-amino-, 2-Aminoethylsulfonic acid, O-Due, 2-Sulfoethylamine, taufon, Aminoethanesulfonic acid, aminoethylsulfonic acid, beta-Aminoethylsulfonic acid, 2-aminoethane-1-sulfonic acid, Taurinum [Latin], Taurina [Spanish], Taurine [INN], Taurine Hydrochloride, FEMA No. 3813, CCRIS 4721, UNII-1EQV5MLY3D, NCI-C60606, AI3-18307, NSC32428, EINECS 203-483-8, NSC 32428, 1EQV5MLY3D, 2-aminoethane sulfonic acid, .beta.-Aminoethylsulfonic acid, 1-Aminoethane-2-sulfonic acid, CHEBI:15891, XOAAWQZATWQOTB-UHFFFAOYSA-N, NCGC00015997-06, DSSTox_CID_1304, DSSTox_RID_76069, DSSTox_GSID_21304, Taurina, Taurinum, 91105-79-2, CAS-107-35-7, SMR000326743, TAU, SR-01000076144, Taurine [USP:INN:BAN], C2H7NO3S, Taurineold, Taukard, tauric acid, taurine potassium, HSDB 8167, Aminoethylsulfonate, Taurine,(S), Taurine (TN), taurine monopotassium, b-Aminoethylsulfonate, Taurine (8CI), 2-Aminoethylsulfonate, 2-aminoethyl sulfonate, beta-Aminoethylsulfonate, PubChem18250, Tocris-0209, 2aminoethanesulfonic acid, Taurine, >=99%, b-Aminoethylsulfonic acid, 2-AminoethanesulfonicAcid, AC1L1ARZ, Lopac-T-0625, WLN: Z2SWQ, 1-Aminoethane-2-sulfonate, ACMC-2098vs, bmse000120, bmse000805, bmse000863, D0C6IE, EC 203-483-8, 2-amino-ethanesulfonic acid, AC1Q54NS, Lopac0_001134, SCHEMBL23068, Taurine, >=98%, FG, Taurine, 99% 100g, KSC178O6B, MLS000859681, MLS001332383, MLS001332384, ARONIS27193, Taurine (JP17/USP/INN), Aminoethylsulfonic acid (JAN), CHEMBL239243, GTPL2379, DTXSID3021304, CTK0H8760, KS-00000ADB, Taurine, >=99.0% (T), MolPort-000-006-300, HMS2093L13, HMS2233D19, HMS3263D09, HMS3370J18, Pharmakon1600-01505463, HY-B0351, KS-000048OD, RKL10149, ZINC3809490, Tox21_110277, Tox21_202520, Tox21_501134, ANW-15782, BDBM50357220, LS-439, MFCD00008197, NSC-32428, NSC759150, s2008, STL197941, AKOS005208848, Tox21_110277_1, CCG-205208, CS-2397, DB01956, Ethanesulfonic acid, 2-amino- (9CI), LP01134, MCULE-6041857208, NE10562, NSC-759150, RP17828, RTR-001805, Taurine, BioUltra, >=99.5% (T), Taurine, SAJ first grade, >=98.5%, TRA-0183757, 107-35-7, 2-Aminoethanesulfonic acid, NCGC00015997-01, NCGC00015997-02, NCGC00015997-03, NCGC00015997-04, NCGC00015997-05, NCGC00015997-07, NCGC00015997-08, NCGC00015997-10, NCGC00024497-01, NCGC00024497-02, NCGC00024497-03, NCGC00024497-04, NCGC00024497-05, NCGC00260069-01, NCGC00261819-01, AJ-45668, AN-22475, AS-13587, I815, NCI60_002814, SC-19115, SBI-0051101.P002, AB1002120, KB-259903, ST2409585, Taurine, Vetec(TM) reagent grade, >=99%, TL8000260, TR-001805, A0295, AM20080018, B1846, EU-0101134, FT-0611241, C00245, D00047, T 0625, AB00443712-07, AB00443712_09, AB00443712_10, I09-0069, J-508042, SR-01000076144-1, SR-01000076144-3, SR-01000076144-5, Taurine, certified reference material, TraceCERT(R), F2191-0280, Z1317839154, Taurine, cell culture tested, meets USP testing specifications, Taurine, United States Pharmacopeia (USP) Reference Standard, Taurine, Pharmaceutical Secondary Standard; Certified Reference Material, Taurine, PharmaGrade, Ajinomoto, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture, taurine zwitterion, aminoetylsulphonic acid, ethylaminesulphonic acid, 2-ammonioethanesulfonate, AC1N3PTE, 2-azaniumylethanesulfonate, 2-azaniumylethane-1-sulfonate, CHEBI:507393, SBB061255, AKOS025117017, CJ-10767, ST51047292, InChI=1/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6

ID: 2617

chemical graph of compound 2617



InChIKey: XOEVKNFZUQEERE-UHFFFAOYSA-N
SMILES: CC1=C(OC2=C(C1=O)C=CC=C2C(=O)OCCN3CCCCC3)C4=CC=CC=C4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 441345
synonyms found at PubChem are:
Flavoxate hydrochloride, 3717-88-2, Flavoxate HCL, DW-61, Bladderon, Peflate, Spasmal, Flavoxate (hydrochloride), DW 61 (flavoxate), UNII-9C05J6089W, Flavoxate hydrochloride, NSC-114649, Rec 7/0040, CHEBI:5089, Rec-7-0040, 2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate hydrochloride, 9C05J6089W, Piperidinoethyl-3-methylflavone-8-carboxylate hydrochloride, 2-Piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate hydrochloride, C24H26ClNO4, DSSTox_CID_27764, DSSTox_RID_82541, DSSTox_GSID_47784, Verrispasmin amp., 3-Methyl-4-oxo-2-phenyl-4H-benzopyran-8-carboxylic acid 2-piperidinyl ethyl ester, 3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid 2-(1-piperidinyl)ethyl ester hydrochloride, NSC114649, NCGC00016636-01, CAS-3717-88-2, SR-01000872667, 2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate;hydrochloride, Prestwick_884, Flavoxate hydrochloride [USAN:USP:JAN], AC1L9B0J, Rec-7-0040 HCl, MLS002154247, SCHEMBL124540, CHEMBL1200875, DTXSID1047784, CTK8B3835, HY-B0549A, KS-00000XSH, AOB5638, MolPort-003-986-802, 1-Piperidinoethanol, hydrochloride, HMS1568B06, BCP13298, Tox21_110537, ANW-43270, MFCD00072099, s4027, AKOS025310107, Flavoxate hydrochloride (JP17/USAN), Tox21_110537_1, AC-1093, API0002707, CCG-220242, CS-2652, RL03419, DW-61;Rec-7-0040;DW61, NCGC00016636-05, AN-15251, AS-12321, BC222362, CC-28434, SMR000499576, ACM1189678430, AB0011722, TL8002737, TR-015131, F0717, FT-0658191, FT-0668549, D00718, J10335, 27814-EP2269989A1, 27814-EP2298767A1, 27814-EP2298772A1, 27814-EP2308839A1, 27814-EP2314587A1, Flavoxate hydrochloride, >=98% (HPLC), solid, C-34896, J-521367, SR-01000872667-1, WLN: T66 BO EVJ CR& D1 JVO2- AT6NTJ &GH, 4H-1-Benzopyran-8-carboxylic acid, 2-piperidinoethyl ester, hydrochloride, Flavoxate hydrochloride, European Pharmacopoeia (EP) Reference Standard, Flavoxate hydrochloride, United States Pharmacopeia (USP) Reference Standard, 1-(2-{[(3-methyl-4-oxo-2-phenyl-4H-chromen-8-yl)carbonyl]oxy}ethyl)piperidinium chloride, 2-(1-piperidyl)ethyl 3-methyl-4-oxo-2-phenyl-chromene-8-carboxylate hydrochloride, 2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate hydrochloride, 2-Piperidinoethyl-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate hydrochloride, 4H-1-Benzopyran-8-carboxylic acid, 2-(1-piperidinyl)ethyl ester, hydrochloride, AKOS015896479, A823554, I06-1881, hydron; 2-piperidin-1-ylethyl 3-methyl-4-oxidanylidene-2-phenyl-chromene-8-carboxylate; chloride, hydron; 3-methyl-4-oxo-2-phenyl-1-benzopyran-8-carboxylic acid 2-(1-piperidinyl)ethyl ester; chloride

ID: 2618

chemical graph of compound 2618



InChIKey: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
SMILES: C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5865
synonyms found at PubChem are:
prednisone, 53-03-2, Dehydrocortisone, Deltasone, Decortin, Meticorten, Orasone, Prednison, Rectodelt, Ultracorten, Dacortin, Encorton, 1,2-Dehydrocortisone, Deltacortisone, Deltacortone, Ancortone, Colisone, Decortancyl, Decortisyl, Deltison, Encortone, Paracort, Prednilonga, Prednisonum, Sterapred, Cortan, Liquid Pred, Di-Adreson, Bicortone, Cortidelt, Dekortin, Diadreson, Enkorton, Hostacortin, Lisacort, Panafcort, Prednidib, Prednizon, Pronison, Servisone, Supercortil, Ultracortene, Zenadrid, Adasone, Cotone, Deltra, Juvason, Lodotra, Nurison, Panasol, Winpred, Wojtab, Metacortandracin, delta-Cortisone, Sone, Apo-Prednisone, Delta-Cortelan, Prednicen-M, Delta-Dome, Delta E, In-Sone, Deltacortene, Incocortyl, Novoprednisone, Parmenison, Prednicorm, Prednicort, Prednisona, Prednitone, Prednovister, Retrocortine, Cartancyl, Dacorten, Dellacort, Deltisona, Econosone, Fiasone, Pehacort, Predeltin, Prednicot, Presone, delta cortelan, Nisona, Nizon, Dellacort A, SK-Prednisone, Me-Korti, Origen Prednisone, Prednisone Intensol, 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione, Prednisonum [INN-Latin], Prednisona [INN-Spanish], delta-1-Cortisone, 1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione, Deltisone, Enkortolon, Kortancyl, Precort, Pronisone, Zenadrid (veterinary), 1-Cortisone, Meticorten (Veterinary), delta(sup 1)-Cortisone, delta-1-Dehydrocortisone, Fernisone, Metrevet (Veterinary), delta(sup 1)-Dehydrocortisone, delta-Cortone, Prednisone [INN:BAN], NCI-C04897, UNII-VB0R961HZT, 1-Dehydrocortisone, NSC 10023, Delta E., U 6020, CCRIS 2646, Zenadrid [veterinary], HSDB 3168, C21H26O5, EINECS 200-160-3, VB0R961HZT, 1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione, AI3-52939, CHEBI:8382, (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione, delta-E, .delta.-Cortisone, Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, .delta.1-Cortisone, NSC-10023, NCGC00090766-01, Meticorten (TN), .delta.1-Dehydrocortisone, P1276, DSSTox_CID_1185, DSSTox_RID_75997, DSSTox_GSID_21185, 17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione, Lodtra, Rayos, Pregna-1,4-diene-3,11,20-trione monohydrate, 17,21-dihydroxy-, (8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione, (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione, (8S,9S,10R,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione, SMR000718760, SMR001227202, MLS002638114, 1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione, Prednisone [USP:INN:BAN], Liquid Pree, .delta.sone, delta1-Cortisone, .delta.-Cortone, .delta.-Cortelan, CAS-53-03-2, prednisone anhydrous, Deltadehydrocortisone, Prednisone(Adasone), Prestwick_405, Meticortelone (TN), .delta. E, .delta.-E, Prednisone (Adasone), delta1-Dehydrocortisone, delta(Sup1)-Cortisone, Prednisone, >=98%, Prestwick0_000077, Prestwick1_000077, Prestwick2_000077, Prestwick3_000077, .delta.(sup1)-Cortisone, modified-release prednisone, CHEMBL635, D0IL7L, 17alpha, 21-Dihydroxypregna-1,4-dien-3,11,20-trione, AC1L1LB2, AC1Q29EZ, SCHEMBL3288, BSPBio_000293, MLS001061265, MLS001304073, MLS001335907, MLS001335908, MLS002154191, MLS002207083, MLS002548880, SPBio_002214, BPBio1_000323, GTPL7096, MEGxm0_000443, DTXSID4021185, ACon0_000082, ACon1_000297, CTK4J6918, MolPort-001-740-041, XOFYZVNMUHMLCC-ZPOLXVRWSA-N, HMS1568O15, HMS2090J13, HMS2095O15, HMS2231I24, HMS3039K07, HMS3259I09, HMS3712O15, 1,21-diol-3,11,20-trione, BCP09049, HY-B0214, NSC10023, ZINC3875357, Tox21_111014, Tox21_201564, Tox21_300196, LMST02030180, MFCD00003608, s1622, AKOS005267096, AKOS007930684, Tox21_111014_1, CCG-220077, CS-2159, DB00635, LS-1325, MCULE-2603291254, NC00475, NE42686, RTR-036991, NCGC00090766-02, NCGC00090766-03, NCGC00090766-04, NCGC00090766-05, NCGC00090766-07, NCGC00254096-01, NCGC00259113-01, Prednisone, tested according to Ph.Eur., AC-11112, AJ-46419, AS-11685, NCI60_000008, SC-73986, AB2000169, TR-036991, Pregna-1,11,20-trione, 17,21-hydroxy-, ST24049033, EN300-52605, Pregna-1,11,20-trione, 17,21-dihydroxy-, 7077-EP2269977A2, 7077-EP2270014A1, 7077-EP2275413A1, 7077-EP2275420A1, 7077-EP2277565A2, 7077-EP2277566A2, 7077-EP2277567A1, 7077-EP2277568A2, 7077-EP2277569A2, 7077-EP2277570A2, 7077-EP2281815A1, 7077-EP2286811A1, 7077-EP2287156A1, 7077-EP2289892A1, 7077-EP2289894A2, 7077-EP2292280A1, 7077-EP2295055A2, 7077-EP2295409A1, 7077-EP2295416A2, 7077-EP2295426A1, 7077-EP2295427A1, 7077-EP2298743A1, 7077-EP2298748A2, 7077-EP2298764A1, 7077-EP2298765A1, 7077-EP2301933A1, 7077-EP2305642A2, 7077-EP2305660A1, 7077-EP2308812A2, 7077-EP2308833A2, 7077-EP2308855A1, 7077-EP2311453A1, 7077-EP2311807A1, 7077-EP2311827A1, 7077-EP2311840A1, 7077-EP2314590A1, C07370, J10219, 003P608, SR-01000837536, SR-01000837536-3, BRD-K85883481-001-04-2, BRD-K85883481-001-08-3, BRD-K85883481-001-25-7, 17alpha,21-dihydroxypregna-1,4-diene-3,11,20-trione, Pregna-1,4-diene-3,11,20-trione, 17,21-hydroxy-, Pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-, WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ, Prednisone, European Pharmacopoeia (EP) Reference Standard, Prednisone, United States Pharmacopeia (USP) Reference Standard, Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone, Prednisone, Pharmaceutical Secondary Standard; Certified Reference Material, Prednisone for peak identification, European Pharmacopoeia (EP) Reference Standard, Prednisone, pharmaceutical secondary standard; traceable to USP, PhEur and BP, (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-3,6-diene-5,17-dione, (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadeca-3,6-diene-5,17-dione, 68-59-7, Prednisone solution, 100 mug/mL in acetonitrile, ampule of 1 mL, certified reference material

ID: 2619

chemical graph of compound 2619



InChIKey: XOGTZOOQQBDUSI-UHFFFAOYSA-M
SMILES: C(CS(=O)(=O)[O-])S.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 29769
synonyms found at PubChem are:
mesna, 19767-45-4, Sodium 2-mercaptoethanesulfonate, Mesnex, Uromitexan, Mitexan, 2-Mercaptoethanesulfonic acid sodium salt, Mistabron, Mesnum, Mistabronco, Mucofluid, Sodium 2-mercaptoethane sulfonate, Mesnum [INN-Latin], Ethanesulfonic acid, 2-mercapto-, monosodium salt, 2-mercaptoethanesulfonic acid sodium, UNII-NR7O1405Q9, Natrium 2-mercaptoethansulfonat, CCRIS 3712, coenzyme M, 2-Mercaptoethane sulfonate sodium, sodium 2-sulfanylethane-1-sulfonate, EINECS 243-285-9, NSC 113891, 2-Mercaptoethanesulfonic,Mesna, 2-Mercapto-ethan-sulfonsaeure, natrium-salz, 2-Mercaptoethanesulfonic acid monosodium salt, 2-Mercaptoethanesulfonate, sodium, NR7O1405Q9, sodium 2-mercaptoethane-1-sulfonate, NCGC00181166-01, DSSTox_CID_809, DSSTox_RID_75800, DSSTox_GSID_20809, SMR000059219, CAS-19767-45-4, C2H5NaO3S2, Mesna [USAN:BAN:INN], D-7093, Mexan, Mesna [USAN:USP:INN:BAN], Mesna, Shionogi, ASTA-D 7093, Sodium 2-Mercaptoethanesulphonate, Uromitexan;Mesnex, Uromitexan (TN), Mesna, coenzyme M, UCB-3983, Mesnex (TN), Prestwick_1005, HS-CoM Na, Coenzyme M sodium salt, Spectrum2_000752, Spectrum3_001483, Spectrum4_000041, Spectrum5_001174, 2-mercaptoethane sulfonate, A M AAENI, ACMC-209f1l, CHEMBL975, D0C3YQ, AC1Q1VK3, AC1Q1VK4, Mesna (JAN/USAN/INN), SCHEMBL7993, Mesna (Uromitexan, Mesnex), KBioGR_000501, KSC542E4T, MLS001074691, MLS001333251, MLS001333252, SPECTRUM1502014, SPBio_000764, 2-UI>>uOO>>CEa AAENI, sodium;2-sulfanylethanesulfonate, DTXSID1020809, CHEBI:31824, CTK4E2249, HMS502F17, KBio3_002565, 3375-50-6 (parent cpd), EBD6310, MolPort-003-666-395, XOGTZOOQQBDUSI-UHFFFAOYSA-M, HMS1921D10, HMS2092N09, HMS2236L05, HMS3259D13, HMS3372M11, HMS3655M06, HMS3715H05, potassium 2-sulfanylethanesulfonate, sodium, 2-mercapto-ethanesulfonate, BCP14384, KS-00000V6Q, Tox21_112767, Tox21_200863, ANW-23767, CCG-40134, MFCD00007535, s1735, 2-MERCAPTOETHANE SULFONIC ACID, AKOS006220661, AKOS015960755, mercaptoethanesulfonic acid sodium salt, Tox21_112767_1, AC-6011, CS-1364, LS-7484, NC00648, RTR-036066, NCGC00094939-01, NCGC00094939-02, NCGC00178318-04, NCGC00258417-01, 2-mercaptoethanesulphonic acid sodium salt, AS-13260, BC204054, CPD000059219, H751, HY-13679, SAM002548937, SC-18811, 2-mercaptoethane sulfonic acid sodium salt, AB0013231, AB2000259, KB-274297, TR-036066, A8469, M0913, ST24049216, EN300-49858, D 7093, D01459, M-2956, AB01274734-01, Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex, W-60283, I09-0289, Q-201713, Ethanesulfonic acid, 2-mercapto-, sodium salt (1:1), Z1741968275

ID: 2620

chemical graph of compound 2620



InChIKey: XOXHILFPRYWFOD-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=C(C=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6634
synonyms found at PubChem are:
Sulfachloropyridazine, sulfachlorpyridazine, 80-32-0, 4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamide, Nefrosul, Sulphachlorpyridazine, Sulfacloropiridazina, Durasulf, Sulfachlorpyridazinum, Sonilyn, N1-(6-Chloro-3-pyridazinyl)sulfanilamide, Cluricol, Vetisulid, 4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide, Vetisulid (Veterinary), Solfaclorpiridazina [DCIT], Ba 10370, UNII-P78D9P90C0, CHEBI:59057, Sulfachlorpyridazinum [INN-Latin], Sulfacloropiridazina [INN-Spanish], Benzenesulfonamide, 4-amino-N-(6-chloro-3-pyridazinyl)-, EINECS 201-269-9, N1-(6-Chlor-3-pyridazinyl)sulfanilamid, MLS000777734, P78D9P90C0, CAS-80-32-0, NCGC00016323-01, NCGC00016323-04, SMR000414174, N(1)-(6-Chloro-3-pyridazinyl)sulfanilamide, N(sup 1)-(6-Chloro-3-pyridazinyl)sulfanilamide, DSSTox_CID_25265, DSSTox_RID_80778, DSSTox_GSID_45265, [(4-aminophenyl)sulfonyl](6-chloropyridazin-3-yl)amine, 4-Amino-N-(6-chloro-pyridazin-3-yl)-benzenesulfonamide, cosulfa, Prinzone vet., Solfaclorpiridazina, SR-01000773478, sulfaclorazina, sulfarene, sulpirazina, Cosulid, Prinzone vet, Sulfachlorpyridazine [USAN:INN], sulfochlorpyridazine, Nefrosul (TN), Prestwick_130, Sulfachlorpyridazine [USP:INN:BAN], Sulphachloropyridazine, Cosumix (Salt/Mix), Spectrum_000127, AC1L1MYP, Prestwick0_000715, Prestwick1_000715, Prestwick2_000715, Prestwick3_000715, Spectrum2_001942, Spectrum3_001221, Spectrum4_000444, Spectrum5_001011, Epitope ID:122243, AC1Q51XA, AC1Q6W2S, cid_6634, Ciba 10370, Oprea1_485631, SCHEMBL94138, BSPBio_000929, BSPBio_002662, KBioGR_000828, KBioSS_000587, SPECTRUM1501142, SPBio_002003, SPBio_002850, BPBio1_001023, Sulfachlorpyridazine (USP/INN), CHEMBL1443577, DTXSID9045265, BDBM90673, CTK7D7908, KBio2_000587, KBio2_003155, KBio2_005723, KBio3_002162, ZINC49140, MolPort-000-889-880, XOXHILFPRYWFOD-UHFFFAOYSA-N, 3-sulfanilamido-6-chloropyridazine, HMS1570O11, HMS1921J11, HMS2092F19, HMS2097O11, HMS2766B06, HMS3714O11, Pharmakon1600-01501142, ALBB-011657, HY-B1781, KS-00000XU1, Tox21_110372, Tox21_112957, AN-721, CCG-39459, MFCD00057371, NSC757858, SBB001158, STK315422, AKOS000308728, Tox21_110372_1, CS-7970, MCULE-9179642576, NSC-757858, NCGC00016323-02, NCGC00016323-03, NCGC00016323-09, NCGC00094909-01, NCGC00094909-02, AC-12002, BC203868, ST007536, N'-(6-Chloro-3-pyridazinyl)sulfanilamide, SBI-0051655.P002, AB0151335, LS-177518, TR-044943, AB00052217, FT-0674699, R1866, D05948, AB00052217_11, SR-01000773478-2, SR-01000773478-3, Sulfachloropyridazine 100 microg/mL in Acetonitrile, W-104238, 4-Amino-N-(6-chloropyridazin-3-yl)-benzenesulfonamide, 4-Amino-N-[6-chloro-3-pyridazinyl]-benzenesulfonamide, BRD-K32021043-001-05-1, I01-15835, 4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide #, 4-amino-N-(6-chloropyridazin-3-yl)benzene-1-sulfonamide, 4-Amino-N-[6-chloro-3-pyridazinyl]- benzenesulfonamide, 4-azanyl-N-(6-chloranylpyridazin-3-yl)benzenesulfonamide, Benzenesulfonamide,4-amino-N-(6-chloro-3-pyridazinyl)-, Pyridazin-3-amine, N-(4-aminophenylsulfonyl)-6-chloro-, Sulfachloropyridazine, VETRANAL(TM), analytical standard, Sulfachlorpyridazine, United States Pharmacopeia (USP) Reference Standard, N'-[(5Z)-7,7-dimethyl-3-oxo-2,6,7,8-tetrahydrocinnolin-5(3H)-ylidene]-N,N-dimethylhydrazonoformamide

ID: 2621

chemical graph of compound 2621



InChIKey: XPCTZQVDEJYUGT-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)C=CO1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8369
synonyms found at PubChem are:
MALTOL, 118-71-8, 3-Hydroxy-2-methyl-4-pyrone, 3-Hydroxy-2-methyl-4H-pyran-4-one, Larixinic acid, Palatone, Talmon, Vetol, Larixic acid, Corps praline, 4H-Pyran-4-one, 3-hydroxy-2-methyl-, 2-Methyl pyromeconic acid, Veltol, 2-Methyl-3-hydroxy-4-pyrone, 2-Methyl-3-hydroxypyrone, Maltol (natural), 3-Hydroxy-2-methyl-gamma-pyrone, 2-Methyl-3-oxy-gamma-pyrone, 2-Methylpyromeconic acid, 3-hydroxy-2-methylpyran-4-one, 3-Hydroxy-2-methylpyrone, 3-Hydroxy-2-methyl-pyran-4-one, 3-Hydroxy-2-methyl-4-pyranone, NSC 2829, UNII-3A9RD92BS4, FEMA No. 2656, CCRIS 3467, 2-methyl-3-hydroxy-4-pyranone, NSC2829, 3-Hydroxy-2-methyl-1,4-pyrone, 3-Hydroxy-2-methyl-.gamma.-pyrone, EINECS 204-271-8, BRN 0112169, AI3-18547, MLS000069412, 3A9RD92BS4, CHEBI:69438, XPCTZQVDEJYUGT-UHFFFAOYSA-N, 5-Hydroxy-6-methyl-4H-pyran-4-one, SMR000059093, DSSTox_CID_5523, DSSTox_RID_77818, DSSTox_GSID_25523, WLN: T6O DVJ B1 CQ, CAS-118-71-8, Maltol [NF], Methylmaltol, methyl maltol, Laricinic acid, Maltol FCC IV, NATURAL MALTOL, Spectrum_001419, ACMC-1BSCT, Opera_ID_338, SpecPlus_000443, AC1L1QUQ, Spectrum2_001795, Spectrum3_001351, Spectrum4_001871, Spectrum5_000462, bmse000538, Maltol, analytical standard, SCHEMBL4815, 3-Hydroxy-2-pyran-4-one, BSPBio_003161, KBioGR_002365, KBioSS_001899, SPECTRUM310025, 5-18-01-00114 (Beilstein Handbook Reference), KSC496O7D, MLS001424145, MLS002415738, 3-Hydroxy-2-methyl-g-pyrone, CHEMBL31422, DivK1c_006539, 3-hydroxy-2-methylpyr-4-one, SPBio_001749, QSPL 180, DTXSID0025523, 2-Methyl-3-oxy-.gamma.-pyrone, 3-hydroxy-2-methyl-4-oxopyrane, 3-hydroxyl-2-methyl-4-pyranone, CTK3J6771, FEMA 2656, HSDB 8320, KBio1_001483, KBio2_001899, KBio2_004467, KBio2_007035, KBio3_002381, XPCTZQVDEJYUGT-UHFFFAOYSA-, MolPort-000-741-877, 2-methyl-3-oxidanyl-pyran-4-one, 3-hydroxy-2-methyl-gamma -pyrone, HMS2052K09, HMS3394K09, KUC106764N, ZINC164488, KS-00000VU7, NSC-2829, STR01642, Tox21_202215, Tox21_300118, ANW-17159, BBL011669, CCG-38443, LS-602, Maltol, natural, >=98.5%, FG, MFCD00006578, NSC404458, SBB055954, STK801686, 2-methyl-3-hydroxy-4H-pyran-4-one, Maltol, >=99.0%, FCC, FG, 3-Hydroxy-2-methyl-4-pyrone, 99%, AKOS005607790, 3-Hydroxy-2-Methyl-4-pyrone, natural, MCULE-2376032845, NC00350, NE10448, NSC-404458, PS-4578, RL00722, RTR-034224, SDCCGMLS-0066563.P001, Maltol (3-Hydroxy-2-methyl-4-pyrone), 4-(a-d-Glucopyranosido)-a-glucopyranose, NCGC00091223-01, NCGC00091223-02, NCGC00091223-03, NCGC00091223-04, NCGC00091223-05, NCGC00178231-01, NCGC00254046-01, NCGC00259764-01, 4CN-2716, AJ-16177, AN-22788, BP-11468, CJ-02148, CPD000059093, E636, KB-32108, KSC-11-228-8, N095, NCI60_002320, SAM001246871, SC-46175, ZB008163, AB1002282, DB-002512, TR-034224, AM20080119, FT-0615804, M0673, Maltol solution, 1 wt. % in benzyl alcohol, ST24028541, ST50330599, C11918, 45190-EP2295424A1, 45190-EP2311821A1, A804081, SR-01000712383, I14-6950, SR-01000712383-3, W-108539, BRD-K40619305-001-12-1, Z1868163292, Maltol, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3

ID: 2622

chemical graph of compound 2622



InChIKey: XPDUPDVRYWORNX-UHFFFAOYSA-N
SMILES: C1(=C(O)C=C(O)C=C1)C(=O)CC(=O)C1=CC=C([NH0+]([OH0-])=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 14861728
synonyms found at PubChem are:
ZINC196490566

ID: 2623

chemical graph of compound 2623



InChIKey: XPDVQPODLRGWPL-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=O)O)S(=O)(=O)N(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3552
synonyms found at PubChem are:
halazone, 80-13-7, Pantocid, Halazon, Cloritines, Pantocide, Pantosid, Pantotsid, Pentocid, Zeptabs, 4-(Dichlorosulfamoyl)benzoic Acid, p-Sulfondichloramidobenzoic acid, Halazono, Halazonum, 4-(N,N-Dichlorosulfamoyl)benzoic acid, p-Carboxybenzenesulfondichloroamide, Parasulfondichloramido benzoic acid, Caswell No. 326, p-(N,N-Dichlorosulfamyl)benzoic acid, p-(N,N-Dichlorosulfamoyl)benzoic acid, Halazonum [INN-Latin], Halazono [INN-Spanish], p-(Dichlorosulfamoyl)benzoic acid, Benzoic acid, 4-[(dichloroamino)sulfonyl]-, UNII-G359OL82VB, Benzoic acid, p-(dichlorosulfamoyl)-, NSC 60717, CCRIS 6243, EINECS 201-253-1, EPA Pesticide Chemical Code 077201, Kyselina p-N,N-dichlorsulfamoylbenzoova, BRN 2740018, p-Dichlorosulfamoylbenzoic acid, G359OL82VB, Benzoic acid, 4-((dichloroamino)sulfonyl)-, Kyselina p-N,N-dichlorsulfamoylbenzoova [Czech], 4-[(dichloroamino)sulfonyl]benzoic acid, NCGC00091225-02, DSSTox_CID_5370, DSSTox_RID_77766, DSSTox_GSID_25370, W-104247, CAS-80-13-7, Halazone [INN], Halazone [USP:INN], (1)thornA-xU, Halazone (USP/INN), Spectrum_000839, WLN: QVR DSWNGG, Spectrum2_000670, Spectrum3_000447, Spectrum4_000569, Spectrum5_000786, AC1L1G6Z, AC1Q6V9R, SCHEMBL29353, BSPBio_002094, KBioGR_000978, KBioSS_001319, 2-11-00-00220 (Beilstein Handbook Reference), DivK1c_000683, SPECTRUM1500324, SPBio_000739, CHEMBL1368146, DTXSID9025370, CTK5E7502, HMS502C05, KBio1_000683, KBio2_001319, KBio2_003887, KBio2_006455, KBio3_001314, MolPort-003-665-532, NINDS_000683, XPDVQPODLRGWPL-UHFFFAOYSA-N, HMS1920B21, HMS2091J07, Pharmakon1600-01500324, NSC60717, ZINC1482080, Tox21_111104, Tox21_202519, CCG-39876, NSC-60717, NSC757053, AKOS015891386, Tox21_111104_1, 4-(N.N-Dichlorosulfamoyl)benzoic acid, LS-1791, NSC-757053, IDI1_000683, NCGC00091225-01, NCGC00091225-03, NCGC00091225-04, NCGC00091225-06, NCGC00260068-01, AN-42173, Benzoic acid,4-[(dichloroamino)sulfonyl]-, SBI-0051400.P003, FT-0616739, p-(N,N-DICHLORO-SULFAMYL)BENZOIC ACID, p-(N,N-DICHLOROSULFAMYL) BENZOIC ACID, D02446, AB00052007_02, SR-05000001638, I01-9698, SR-05000001638-1, p-(N,N-Dichlorosulfamyl)benzoic acid, analytical standard, >=70% (TLC)

ID: 2624

chemical graph of compound 2624



InChIKey: XQCJOYZLWFNDIO-PKLMIRHRSA-N
SMILES: CC1CCN(CC1)CC[C@H]2CCCN2S(=O)(=O)C3=CC=CC(=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957684
synonyms found at PubChem are:
SB 269970 hydrochloride, SB-269970 hydrochloride, 261901-57-9, (R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol hydrochloride, SB-269970 (hydrochloride), SB269970 HCl, SB 269970A, (R)-3-[2-[2-(4-Methylpiperidin-1-yl)ethyl]pyrrolidine-1-sulfonyl]phenol hydrochloride, SR-01000076135, EU-0101059, SB269970 hydrochloride, D0BG5H, C18H29ClN2O3S, MLS002153418, SB 269970 hcl, SCHEMBL2719586, CHEMBL1256844, CTK8B9470, KS-00000XMZ, SB-269970 HCl, MolPort-003-959-592, BCP14529, Tox21_501059, 2275AB, ABP000324, ANW-62575, BN0629, HY-15370A, MFCD03788020, s2849, AKOS016004346, CCG-222363, CS-1644, LP01059, SB 269970-A, NCGC00094341-01, NCGC00261744-01, SMR001230794, AX8233428, KB-145964, RT-015655, S 7389, J-013020, J-016312, SR-01000076135-2, SR-01000076135-3, SB-269970 hydrochloride, powder, >=98% (HPLC), (R)-3-((2-(2-(4-METHYLPIPERIDIN-1-YL)ETHYL)PYRROLIDIN-1-YL)SULFONYL)PHENOL HCL, [R]-3-[2-(2-[4-Methyl-piperidin-1-yl]ethyl)pyrrolidine-1-sulfonyl]phenol hydrochloride, (2r)-1-[(3-hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl] pyrrolidine hydrochloride, (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride

ID: 2625

chemical graph of compound 2625



InChIKey: XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281813
synonyms found at PubChem are:
Wedelolactone, 524-12-9, UNII-0K6L725GNS, 7-Methoxy-5,11,12-trihydroxy-coumestan, 1,8,9-Trihydroxy-3-methoxycoumestan, Wedelolactone, Eclipta alba, 7-Methoxy-5,11,12-trihydroxycoumestan, CHEMBL97453, 0K6L725GNS, CHEBI:10037, IKK Inhibitor II, Wedelolactone, 5,11,12-Trihydroxy-7-methoxycoumestan, 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-benzofuro[3,2-c]chromen-6-one, 1,8,9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one, AC1NQZ4Z, D0F8QJ, SCHEMBL601220, GTPL5551, CTK8G3781, DTXSID60200408, MolPort-003-960-187, Wedelolactone, analytical standard, HMS2043P19, BCP19859, ZINC6483512, BDBM50096619, CM-842, LMPK12090046, MFCD07778564, AKOS015897173, CCG-208289, SMP2_000112, NCGC00163667-01, NCGC00163667-02, NCGC00163667-03, Wedelolactone, >=98% (HPLC), powder, AN-45548, SC-67595, FT-0698529, N2131, C10541, K00058, 524W129, SR-05000002318, I07-0266, SR-05000002318-2, BRD-K53635676-001-01-5, BRD-K53635676-001-02-3, Wedelolactone; 7-Methoxy-5,11,12-trihydroxy-coumestan, 1,8,9-trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one, 1,8,9-trihydroxy-3-methoxy-[1]benzoxolo[3,2-c]chromen-6-one, Wedelolactone, European Pharmacopoeia (EP) Reference Standard, 1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]chromen-6-one, 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-, 6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy-

ID: 2626

chemical graph of compound 2626



InChIKey: XQFRJNBWHJMXHO-RRKCRQDMSA-N
SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5905
synonyms found at PubChem are:
idoxuridine, 5-Iodo-2'-deoxyuridine, 54-42-2, 5-Iododeoxyuridine, Idoxuridin, Iododeoxyridine, Iodoxuridine, IUDR, Joddeoxiuridin, Idoxene, Allergan 211, IDUR, Virudox, 5IUDR, (+)-5-Iodo-2'-deoxyuridine, Idoxuridinum, Antizona, Idoxuridina, Heratil, Allergan 201, Idossuridina [DCIT], IDU, Herpid, Herplex, Stoxil, Iduoculos, Dendrid, IdUrd, Iduridin, Kerecid, 2'-Deoxy-5-iodouridine, Herplex liquifilm, Idoxuridinum [INN-Latin], Idoxuridina [INN-Spanish], Ophthalmadine, Spectanefran, Herpesil, Iduviran, Emanil, Herpidu, Idexur, Iducher, Idulea, Synmiol, 5IdU, Idu Oculos, SK&F-14287, 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil, 1beta-D-2'-Deoxyribofuranosyl-5-iodouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil, 5-Iodouracil deoxyriboside, Iododeoxyuridine, Allergan-211, UNII-LGP81V5245, C9H11IN2O5, CCRIS 2827, URIDINE, 2'-DEOXY-5-IODO-, CHEBI:147675, 5-IUDR, EINECS 200-207-8, NSC-39661, BRN 0030397, Idossuridina, Kerecide, (+)-5-Iodo-2-deoxyuridine, AI3-50861, Oftan-IDU, LGP81V5245, NSC 39661, Uracil, 5-iodo-1-(2-deoxy-beta-D-ribofuranosyl)-, Uridine, 5-iodo-2'-deoxy-, 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione, ID2, SKF 14287, SK&F 14287, DSSTox_CID_25238, DSSTox_RID_80769, DSSTox_GSID_45238, Herpes-Gel, (+)-5-Iodo-2 -deoxyuridine, Herpe-Gel, 5-Iododesoxyuridine, Idoxuridine [USAN:INN:BAN:JAN], Dendrid (TN), 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione, HERPLEX (TN), 5-I-2'-dUrd, SR-05000001510, HSDB 7479, CAS-54-42-2, NCGC00016243-01, 5-Iodo-deoxyuridine, 33995-05-0, Idoxuridine [USAN:USP:INN:BAN:JAN], 5-iodo-2'deoxyuridine, Idoxuridine (5-IdU), PubChem14202, Prestwick3_000018, CHEMBL788, D02IED, Epitope ID:138107, AC1L1LE0, AC1Q77TF, SCHEMBL3683, BSPBio_000055, 4-24-00-01235 (Beilstein Handbook Reference), MLS002154175, 5-IODO-2-DEOXYURIDINE, BPBio1_000061, Idoxuridine (JP17/USP/INN), DTXSID2045238, SCHEMBL15850897, CTK4D1152, AOB5602, MolPort-001-792-514, XQFRJNBWHJMXHO-RRKCRQDMSA-N, HMS2090M10, HMS2095C17, HMS2230E10, HMS3712C17, HY-B0307, KS-00000JH7, ZINC3834173, Tox21_110324, ANW-32073, BDBM50370388, MFCD00134656, s1883, AKOS015920431, Tox21_110324_1, (+)-5-Iodo-2'-deoxyuridine, 98%, AC-8219, CCG-220018, CS-2346, DB00249, MCULE-5585466189, SMP2_000072, uridine, 2'-deoxy-5-(iodo-131I)-, NCGC00179673-01, NCGC00179673-03, AJ-45810, AK-35587, AS-13469, BR-35587, CJ-10798, I381, SC-16201, SMR001233472, AB0013659, AX8021350, DB-009133, LS-160825, TL8003566, 5-Iodo-2'-deoxyuridine, >=99% (HPLC), I0258, 1-(2-Deoxy- -D-ribofuranosyl)- 5-iodouracil, C-1149, D00342, 16509-EP2281563A1, 16509-EP2316459A1, 20495-EP2272827A1, 20495-EP2298768A1, 20495-EP2314585A1, 134I656, J-009907, J-700180, SR-05000001510-1, SR-05000001510-3, SR-05000001510-4, BRD-K76634210-001-14-7, Idoxuridine, European Pharmacopoeia (EP) Reference Standard, Idoxuridine, United States Pharmacopeia (USP) Reference Standard, 2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-iodo-, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione, 1336-77-2, 888-04-0

ID: 2627

chemical graph of compound 2627



InChIKey: XQOSNJUURCKQGN-AXSGJTORSA-N
SMILES: CC1=C2C(C(=O)OC3[C@@]2(C(CC1)[C@]4(C=CC(=O)C(C4C3)(C)C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708642
synonyms found at PubChem are:
MEROGEDUNIN, KBio2_006171, Spectrum_000555, SpecPlus_000295, Spectrum2_000337, Spectrum3_000086, Spectrum4_001372, Spectrum5_000044, BSPBio_001612, KBioGR_001664, KBioSS_001035, SPECTRUM100455, DivK1c_006391, SPBio_000373, CHEMBL3039254, KBio1_001335, KBio2_001035, KBio2_003603, KBio3_000692, CCG-38612, SDCCGMLS-0066293.P001, NCGC00179151-01, SR-05000002605, SR-05000002605-1, BRD-A21423998-001-03-4

ID: 2628

chemical graph of compound 2628



InChIKey: XQWBNXSENPTIDY-YXMARJSJSA-N
SMILES: C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9912668
synonyms found at PubChem are:
Phlorizin dihydrate, 7061-54-3, Phloridzin dihydrate, Phloridzin dihydrate, 99%, SCHEMBL8861774, MolPort-003-928-949, KS-00000R2I, C21H24O10.2H2O, C21H28O12, MFCD00149438, AKOS015895414, DS-5771, Phloridzin dihydrate, analytical standard, AK119797, AX8245213, ST24048910, 149P438, Q-100786, Phloretin 2 inverted exclamation marka-|A-D-glucoside, Phloridzin dihydrate, from apple wood, >=99% (HPLC), Phloretin 2 inverted exclamation marka-|A-D-glucopyranoside, 1-[2-(|A-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, 1-(2,4-dihydroxy-6-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one dihydrate, 1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate

ID: 2629

chemical graph of compound 2629



InChIKey: XQZXYNRDCRIARQ-LURJTMIESA-N
SMILES: C[C@@H](C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 65492
synonyms found at PubChem are:
iopamidol, Iopamiron, 60166-93-0, Iopamiro, Isovue, Niopam, Solutrast, Gastromiro, Iopamidol 300, Solutrast 370, Iopamidolum, Oypalomin, Isovue 370, Iopamiron 300, Iopamiron 370, Jopamiron 200, Iopamiro 370, Isovue-370, Niopam 300, iomapidol, Iopamidolum [INN-Latin], UNII-JR13W81H44, B-15000, EINECS 262-093-6, B 15000, BRN 6250226, SQ 13396, SQ-13396, (S)-N,N'-bis(2-Hydroxy-1-(hydroxymethyl)ethyl)-2,4,6-triiodo-5-lactamidoisophthalamide, L-(+)-N,N'-Bis(2-hydroxy-1-hydroxymethylethyl)-2,4,6-triiodo-5-lactamide isophthalamide, L-5alpha-Hydroxypropionylamino-2,4,6-triiodoisophthalic acid di(1,3-dihydroxy-2-propylamide), CHEBI:31711, JR13W81H44, 62883-00-5, NCGC00016892-01, CAS-60166-93-0, DSSTox_CID_3158, DSSTox_RID_76896, L-5alpha-Idrossipropionilamino-2,4,6-triiodoisoftal-di(1,3-diidrossi-2-propilamide), DSSTox_GSID_23158, (S)-N,N'-Bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodoisophthaldiamide, 1,3-Benzenedicarboxamide, N,N'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-(((2S)-2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-, 1,3-Benzenedicarboxamide, N,N'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-, (S)-, 1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-[[(2S)-2-hydroxypropanoyl]amino]-2,4,6-triiodobenzene-1,3-dicarboxamide, N,N'-bis(1,3-dihydroxypropan-2-yl)-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodobenzene-1,3-dicarboxamide, Iopamidol-200, Iopamidol-250, Iopamidol-300, Iopamidol-370, Scanlux-300, Scanlux-370, Isovue-128, Isovue-200, Isovue-250, Isovue-300, Isovue-M 200, Isovue-M 300, Iopamyron, Jopamiro, HSDB 8075, (S)-N,N'-Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactamidoisophthalamide, Iopamidol [USAN:INN:BAN:JAN], Iopamiron (TN), Iopamidol-200 in plastic container, Iopamidol-250 in plastic container, Iopamidol-300 in plastic container, Iopamidol-370 in plastic container, Isovue (TN), Iopamidol [USAN:USP:INN:BAN:JAN], SQ 13,396, AC1Q4PBP, Prestwick0_000871, Prestwick1_000871, Prestwick2_000871, Prestwick3_000871, Iopamidol (JP17/USP), D0O2HQ, AC1L23CM, Iopamidol injection (JP17), SCHEMBL27781, BSPBio_000941, SPBio_002862, BPBio1_001037, CHEMBL1200932, DTXSID1023158, MolPort-003-848-224, XQZXYNRDCRIARQ-LURJTMIESA-N, HMS1570P03, HMS2097P03, HMS3714P03, Pharmakon1600-01502304, ACT03261, HY-B0684, ZINC3830947, Tox21_110668, GP4065, NSC759636, s4532, AKOS015891034, Tox21_110668_1, API0003016, CCG-213024, CS-2917, DB08947, KS-1421, NSC-759636, NCGC00016892-02, NCGC00016892-04, AN-39478, CC-29575, LS-29730, SC-43948, AB00513941, FT-0627281, D01797, hydroxypropanamido)-2,4,6-triiodoisophthalamide, AB00513941_02, 166I930, C-23510, I01-8407, Q-201245, (S)-N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-, BRD-K75868704-001-01-2, (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamide, (S)-N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide, N,N inverted exclamation mark -Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxamide, N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-{[(2S)-2-hydroxypropanoyl]amino}-2,4,6-triiodobenzene-1,3-dicarboxamide, N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-[(2S)-2-hydroxypropanamido]-2,4,6-triiodobenzene-1,3-dicarboxamide, N1,N3-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxypropanoyl]amino]-2,4,6-triiodo-benzene-1,3-dicarboxamide

ID: 2630

chemical graph of compound 2630



InChIKey: XRBMKGUDDJPAMH-UHFFFAOYSA-N
SMILES: CC1=CC=CC(=C1OC(=O)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 78094
synonyms found at PubChem are:
4386-39-4, 2-(Acetyloxy)-3-methylbenzoic acid, 2-Acetoxy-3-methylbenzoic acid, 2-Acetoxy-m-toluic acid, UNII-2G83E641HZ, 2-Acetoxy-3-methyl-benzoic acid, 2-acetyloxy-3-methylbenzoic acid, 3-methylacetylsalicylic acid, Benzoic acid,2-(acetyloxy)-3-methyl-, 2G83E641HZ, Cresopirine, NSC49105, EINECS 224-499-1, CRESOPYRINE, Spectrum_001374, Maybridge3_006075, Spectrum2_000555, Spectrum3_001816, Spectrum4_000260, Spectrum5_001737, 3-Methylacetylsalicylsaure, AC1L2UH4, AC1Q1LA1, BSPBio_003431, KBioGR_000700, KBioSS_001854, SPECTRUM1401414, SPBio_000629, SCHEMBL1315833, ZINC1221, 3-Methyl-2-acetoxybenzoic Acid, CHEMBL1234172, CTK4I7839, KBio2_001854, KBio2_004422, KBio2_006990, KBio3_002934, KS-00003TEL, DTXSID40195964, 2-acetoxyl-3-methyl-benzoic acid, MolPort-000-146-114, XRBMKGUDDJPAMH-UHFFFAOYSA-N, 2-acetyloxy-3-methyl-benzoic acid, HMS1448E03, HMS3264F10, ZX-AT028338, BBL018945, CCG-50708, FCH916728, NSC-49105, SBB052707, STK360114, AKOS000109238, ACM4386394, MCULE-6533937024, VZ23464, IDI1_017462, 2-(AcetYl-Oxy)-3-Methyl-Benzoic Acid, NCGC00095965-01, NCGC00095965-02, CC-08510, KB-15298, TS-02755, AB1007738, DB-051175, BB 0245759, FT-0610941, ST50409471, T7849, X5293, AB00053091_02, A826449, C-08653, SR-01000640067-1, I14-90583

ID: 2631

chemical graph of compound 2631



InChIKey: XRCFXMGQEVUZFC-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2197
synonyms found at PubChem are:
anisindione, Miradon, 117-37-3, Anisin indandione, Unidone, 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione, 2-p-Anisyl-1,3-indandione, Anisindionum, Anisindiona, 2-(4-Methoxyphenyl)indan-1,3-dione, 1H-Indene-1,3(2H)-dione, 2-(4-methoxyphenyl)-, 2-(p-Methoxyphenyl)-1,3-indandione, 2-para-Anisyl-1,3-indandione, 2-(p-Methoxyphenyl)indane-1,3-dione, Anisindionum [INN-Latin], Anisindiona [INN-Spanish], SPE 2792, Anisindione [INN:BAN], UNII-S747T1ERAJ, Miradon (TN), Anisindione (INN), HSDB 3205, C16H12O3, EINECS 204-186-6, CHEMBL712, 2-(4-methoxyphenyl)indene-1,3-dione, BRN 1880681, S747T1ERAJ, 1,3-Indandione, 2-(p-methoxyphenyl)-, 2-(4-Methoxy-phenyl)-indan-1,3-dione, 1,3-Indanedione, 2-(4-methoxyphenyl)-, MLS000554135, CHEBI:133809, 2-(4-methoxyphenyl)indane-1,3-dione, NCGC00094969-01, SMR000146452, DSSTox_CID_2611, DSSTox_RID_76658, DSSTox_GSID_22611, 2-[4-(methyloxy)phenyl]-1H-indene-1,3(2H)-dione, CAS-117-37-3, SR-01000642873, Anisindione [INN:BAN:NF], Spectrum_001355, Opera_ID_1613, Spectrum2_000427, Spectrum3_001525, Spectrum4_000723, Spectrum5_000960, D09WKB, Oprea1_729452, SCHEMBL49379, BSPBio_002910, KBioGR_000986, KBioSS_001835, 3-08-00-02931 (Beilstein Handbook Reference), MLS001201835, DivK1c_000336, SPECTRUM1502198, SPBio_000414, AC1L1D53, GTPL6960, DTXSID3022611, CTK7A2798, HMS501A18, KBio1_000336, KBio2_001835, KBio2_004403, KBio2_006971, KBio3_002410, MolPort-002-318-562, NINDS_000336, XRCFXMGQEVUZFC-UHFFFAOYSA-N, HMS1921L18, HMS2092F04, HMS2231B10, HMS3369M11, Pharmakon1600-01502198, ALBB-013687, HY-B0924, KS-00001F9T, ZX-AN012459, Tox21_111370, 9940AC, BDBM50280155, CCG-40244, NSC759629, STK363125, AKOS000987728, Tox21_111370_1, ZINC100015486, API0009036, DB01125, MCULE-6278934749, NSC-759629, IDI1_000336, NCGC00094969-02, NCGC00094969-03, NCGC00094969-05, LS-81215, ST086181, SBI-0051739.P002, AX8077967, FT-0631668, D07457, AB00052289_10, AB00052289_11, I10-1303, J-003611, SR-01000642873-1, SR-01000642873-3, SR-01000642873-4, 2-(4-methoxyphenyl)-2,3-dihydro-1H-indene-1,3-dione, A2429/0102869, 2-(4-methoxyphenyl)-2-hydrocyclopenta[1,2-a]benzene-1,3-dione

ID: 2632

chemical graph of compound 2632



InChIKey: XRECTZIEBJDKEO-UHFFFAOYSA-N
SMILES: C1=NC(=O)NC(=C1F)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3366
synonyms found at PubChem are:
5-Fluorocytosine, flucytosine, 2022-85-7, Ancotil, Ancobon, Flucytosin, 5-Fluorocystosine, Fluocytosine, 5-FC, 5-Fluorocytosin, Fluorcytosine, Alcobon, 4-Amino-5-fluoropyrimidin-2(1H)-one, Flucytosinum, 4-Amino-5-fluoro-2(1H)-pyrimidinone, Ro 2-9915, Cytosine, 5-fluoro-, 5-fluoro cytosine, Flucitosina, 5-Flurocytosine, 5-Flucytosine, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-, 2-Hydroxy-4-amino-5-fluoropyrimidine, Flucitosina [DCIT], Flucystine, Ro 29915 E/265601, Flucytosinum [INN-Latin], Ancobon (TN), Flucytosine (Ancobon), 4-Amino-5-fluoro-2-hydroxypyrimidine, Flucytosone, Ancotyl, NSC 103805, 117969-88-7, UNII-D83282DT06, 4-amino-5-fluoropyrimidin-2-ol, HSDB 3082, 6-Amino-2-oxo-5-fluoropyrimidine, Flucytosine [USAN:INN:BAN:JAN], EINECS 217-968-7, 6-amino-5-fluoro-1H-pyrimidin-2-one, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-), 2-Pyrimidinol, 4-amino-5-fluoro- (9CI), MLS000069463, CHEBI:5100, 4-AMINO-2-HYDROXY-5-FLUOROPYRIMIDINE, XRECTZIEBJDKEO-UHFFFAOYSA-N, 4-Amino-5-fluoro-2-hyroxypyrimidine, NSC103805, D83282DT06, 4-Amino-5-fluoro-1H-pyrimidin-2-one, Ro-2-9915, NCGC00016599-01, CPD000059047, SMR000059047, ST028644, 2(1H)-Pyrimidinone, 6-amino-5-fluoro-, 6-amino-5-fluoro-3-hydropyrimidin-2-one, CAS-2022-85-7, F0321, DSSTox_CID_3059, 6-amino-5-fluoro-1,2-dihydropyrimidin-2-one, C4H4FN3O, DSSTox_RID_76856, DSSTox_GSID_23059, 130256-61-0, flucytosina, 5-fluorocytocine, Flucytosine,(S), 5 Fluoro Cytosine, Flucytosine(Ancobon), zlchem 343, Flucytosine [USAN), Flucytosine (5-FC), Flucytosine [USAN:USP:INN:BAN:JAN], ACMC-209zxs, Opera_ID_178, AC1L1FRT, Prestwick0_000934, Prestwick1_000934, Prestwick2_000934, Prestwick3_000934, D0S5WG, EC 217-968-7, AC1Q52OQ, WLN: T6MVNJ DZ EF, CHEMBL1463, SCHEMBL24063, BSPBio_000868, MLS000759519, MLS001076503, MLS001424013, Flucytosine, 5-Fluorocytosine, SPBio_003037, BPBio1_000956, Flucytosine (JP15/USP/INN), Flucytosine (JP17/USP/INN), DTXSID3023059, SCHEMBL14696800, CTK7B7906, CTK7E0508, CTK8A0854, QCR-271, ZLC0185, MolPort-000-155-561, MolPort-001-774-493, MolPort-002-317-353, 4-amino-5-fluoro-pyrimidin-2-ol, HMS1570L10, HMS2051M04, HMS2093J05, HMS2097L10, HMS2233I14, HMS3373L05, HMS3393M04, HMS3655G17, HMS3714L10, Pharmakon1600-01505429, ZINC896546, 5-Fluorocytosine, 98% 250mg, 5-Fluorocytosine, nucleoside analog, AMX10130, BCP02877, Flucytosine 2.0 mg/ml in Methanol, HY-B0139, Tox21_110515, ANW-50846, CF-075, MFCD00006035, NSC759130, Ro-29915, s1666, SBB000061, STK292386, AKOS004912683, AKOS005063821, AKOS015896898, AKOS030241326, Tox21_110515_1, 2-Hydroxy-4-amino-5-fluoro-pyrimidine, 6-amino-5-fluoropyrimidin-2(1H)-one, AN-9456, BCP9000692, CCG-100837, CCG-213434, CS-1935, Cytosine, 5-fluoro-(6CI,7CI,8CI), DB01099, GL663142 & 5FC, GS-5578, KS-1060, LS40595, MCULE-7094058995, NC00087, NSC-103805, NSC-759130, KS-00000A18, Cytosine, 5-fluoro- (6CI,7CI,8CI), NCGC00016599-02, NCGC00016599-04, NCGC00016599-05, AC-11748, AJ-24237, BC203393, BR-33991, LS-59140, NCI60_000093, SAM001246753, SC-09037, ZB015095, BCP0726000281, AB0005647, AB0071040, AB1000113, DB-005380, KB-189054, TL8001667, 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE, 5987P, 9074P, AB00513969, AM20090149, FT-0601273, LT00771985, 5-fluoro-4-imino-1,3-dihydropyrimidin-2-one, 22P857, 4-Amino-1,2-dihydro-5-fluoro-2-oxopyrimidine, B-7734, D00323, F-3010, 16469-EP2281563A1, 16469-EP2316459A1, AB00444223-16, AB00513969-02, AB00513969_03, AB00513969_04, 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine, 5-Fluorocytosine, Vetec(TM) reagent grade, 99%, SR-01000721885, Flucytosine|||6-Amino-5-fluoropyrimidin-2(1H)-one, I07-0006, SR-01000721885-5, BRD-K82143716-001-15-7, GL663142 & 4-Amino-5-fluoropyrimidin-2(1H)-one, 5-Fluorocytosine, Antibiotic for Culture Media Use Only, Flucytosine, European Pharmacopoeia (EP) Reference Standard, 2(1H)-Pyrimidinone, 5-fluoro-3,4-dihydro-4-imino- (9CI), Flucytosine, United States Pharmacopeia (USP) Reference Standard, Flucytosine, Pharmaceutical Secondary Standard; Certified Reference Material, Flucytosine for system suitability, European Pharmacopoeia (EP) Reference Standard, 1LD

ID: 2633

chemical graph of compound 2633



InChIKey: XRQSPUXANRGDAV-UHFFFAOYSA-N
SMILES: COC1=CC=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 94525
synonyms found at PubChem are:
5-Methoxyflavone, 42079-78-7, 5-methoxy-2-phenyl-4h-chromen-4-one, 5-methoxy-2-phenylchromen-4-one, 5-Methoxy-2-phenyl-4-benzopyrone, CHEMBL16685, 4H-1-Benzopyran-4-one, 5-methoxy-2-phenyl-, 5-Methoxy-2-phenyl-chromen-4-one, ST069360, EINECS 255-652-0, 5 - Methoxyflavone, ACMC-20am2h, AC1Q6AKD, D0V5HF, AC1L3SE9, Oprea1_842256, Oprea1_859852, BIDD:ER0473, ghl.PD_Mitscher_leg0.1155, MEGxp0_001704, SCHEMBL1629391, ZINC5954, ACon1_000175, DTXSID40194917, MolPort-001-742-472, XRQSPUXANRGDAV-UHFFFAOYSA-N, KS-000014KU, 5875AH, BDBM50296862, MFCD00016942, AKOS000599908, CCG-208437, MCULE-3326111781, ACM42079787, NCGC00142613-01, NCGC00142613-02, NCGC00142613-03, NCGC00180810-01, AK324079, ZB000625, KB-197929, TC-168272, FT-0620566, M2365, A-7797, C-57551, SR-05000002253, SR-05000002253-2, BRD-K81383664-001-01-2, I14-57807

ID: 2634

chemical graph of compound 2634



InChIKey: XSFJVAJPIHIPKU-XWCQMRHXSA-N
SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@]35C)F)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 82153
synonyms found at PubChem are:
flunisolide, 3385-03-3, Rhinalar, Synaclyn, Aerobid, Flunisolide HFA, Bronalide, Nasarel, Syntaris, Flunisolida, Lunis, Flunisolidum, Nasalide, Aerospan, Flunisolide [INN], Flunisolide (anhydrous), Flunisolide [anhydrous], Flunisolidum [INN-Latin], RS-3999, Flunisolida [INN-Spanish], UNII-78M02AA8KF, Nisolid, Soluzione, MLS002153928, 78M02AA8KF, CHEBI:5106, Aerobid M, EINECS 222-193-2, RS 3999, DSSTox_CID_25534, DSSTox_RID_80936, DSSTox_GSID_45534, Flunisolide Hemihydrate, 6-Fluoro-11,21-dihydroxy-16,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione, 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone, Pregna-1,4-diene-3,20-dione, 6-alpha-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-, CAS-3385-03-3, 77326-96-6, Flunie, NCGC00016983-01, lunisolide anhydrous, Prestwick_223, Flunisolide(Nasalide)/, Prestwick0_000643, Prestwick1_000643, Prestwick2_000643, Prestwick3_000643, AC1L32UV, SCHEMBL4351, CHEMBL1512, BSPBio_000645, SPBio_002566, BPBio1_000711, GTPL7076, DTXSID1045534, MolPort-005-943-434, HMS1570A07, HMS2097A07, HMS2236A06, HMS3259L10, HMS3714A07, HY-B1121, ZINC4097305, Tox21_110725, ABP000528, MFCD00133324, AKOS025402038, Tox21_110725_1, AC-3514, BCP9000696, CCG-220643, CS-4713, DB00180, NC00716, 6 alpha-fluorodihydroxy-16 alpha,17 alpha-isopropylidenedioxy-1,4-pregnadiene-3,20- dione, NCGC00179492-01, NCGC00179492-03, 6 alpha-fluoro-11 beta,16 alpha,17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16, 17-acetal with acetone, AN-12914, Q834, SMR001233272, AB1010905, LS-118464, C07005, 32277-EP2281815A1, 32277-EP2295402A2, 32277-EP2301933A1, 32277-EP2305640A2, 32277-EP2308562A2, 32277-EP2311827A1, 32277-EP2371811A2, 385F033, BRD-K49577446-001-03-1, 6-Fluoro-11,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide, (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0;{2,9}.0;{4,8}.0;{13,18}]icosa-14,17-dien-16-one, (6a,11b,16a)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

ID: 2635

chemical graph of compound 2635



InChIKey: XSGWRNKNCNDJLK-UHFFFAOYSA-N
SMILES: CC1CCC2=C(C=C3C(=C2O)C(=O)C=C(O3)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 612556
synonyms found at PubChem are:
DIHYDROPTAEROXYLIN, 13475-13-3, SPBio_000521, Spectrum_000741, SpecPlus_000210, AC1LD5RK, Spectrum2_000371, Spectrum3_000138, Spectrum4_001415, Spectrum5_000210, BSPBio_001816, KBioGR_001830, KBioSS_001221, DivK1c_006306, CHEMBL3039136, CHEBI:91955, KBio1_001250, KBio2_001221, KBio2_003789, KBio2_006357, KBio3_000996, XSGWRNKNCNDJLK-UHFFFAOYSA-N, CCG-38644, 4H-Pyrano[3,2-h][1]benzoxepin-4-one, 6,7,8,9-tetrahydro-5-hydroxy-2,8-dimethyl-, NCGC00178982-01, BRD-A91477472-001-01-4, 5-Hydroxy-2,8-dimethyl-6,7,8,9-tetrahydro-4H-oxepino[3,2-g]chromen-4-one #, 5-hydroxy-2,8-dimethyl-6,7,8,9-tetrahydropyrano[3,2-h][1]benzoxepin-4-one, 6,7,8,9-Tetrahydro-5-hydroxy-2,8-dimethyl-4H-pyrano[3,2-h][1]benzoxepin-4-one

ID: 2636

chemical graph of compound 2636



InChIKey: XTKDAFGWCDAMPY-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 15443
synonyms found at PubChem are:
Azaperone, 1649-18-9, Stresnil, Azaperon, Fluoperidol, Suicalm, Azeperone, Eucalmyl, Sedaperone vet, Azaperona, Azaperonum, R-1929, NSC 170976, Azaperonum [INN-Latin], Azaperona [INN-Spanish], 1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-, UNII-19BV78AK7W, 1-(3-(4-Fluorobenzoyl)propyl)-4-(2-pyridyl)piperazine, C19H22FN3O, CCRIS 1586, 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butanone, 4'-Fluoro-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone, EINECS 216-715-8, R 1929, BRN 0565491, MLS003106751, 19BV78AK7W, CHEMBL340211, CHEBI:88301, 1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one, 1-(4-fluorophenyl)-4-(4-(pyridin-2-yl)piperazin-1-yl)butan-1-one, 1-Butanone, 1-(4-fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-, NSC170976, NCGC00016590-01, Butyrophenone, 4'-fluoro-4-[4-(2-pyridyl)-1-piperazinyl]-, CAS-1649-18-9, 1-(4-fluorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one, DSSTox_CID_25361, DSSTox_RID_80826, DSSTox_GSID_45361, 4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone, 1-(4-fluorophenyl)-4-[4-(2-pyridyl)piperazin-1-yl]butan-1-one, 1-(4-Fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone, BUTYROPHENONE, 4'-FLUORO-4-(4-(2-PYRIDYL)-1-PIPERAZINYL)-, SMR001233462, SR-05000001712, Azaperone [USAN:INN:BAN], azaperone(usp), Azaperone [USAN:USP:INN:BAN], Stresnil (TN), Azaperone (USP/INN), AC1Q4NJV, Prestwick0_001117, Prestwick1_001117, Prestwick2_001117, Prestwick3_001117, Spectrum2_001250, Spectrum3_001966, D0Q7FM, AC1L25WI, BSPBio_001254, BSPBio_003566, 5-23-03-00041 (Beilstein Handbook Reference), MLS002154163, SCHEMBL121134, SPECTRUM1505332, SPBio_001160, SPBio_003117, BPBio1_001379, DTXSID2045361, CTK8E9220, KBio3_002914, MolPort-002-508-199, XTKDAFGWCDAMPY-UHFFFAOYSA-N, HMS1571O16, HMS1922D20, HMS2090K03, HMS2093D03, HMS2098O16, HMS2230C17, HMS3369I10, HMS3652D15, HMS3715O16, Pharmakon1600-01505332, BCP12176, HY-B1470, ZINC2596977, Tox21_110512, BBL011031, BDBM50036733, CCG-39158, NSC758969, PDSP1_000828, PDSP2_000815, s4219, STK802185, AKOS005622715, Tox21_110512_1, AM84563, API0001568, CS-5158, KS-5204, MCULE-4749695585, NSC-170976, NSC-758969, VA10355, NCGC00016590-02, NCGC00016590-03, NCGC00016590-04, NCGC00016590-06, NCGC00016590-08, NCGC00095171-01, NCGC00095171-02, NCGC00095171-03, AN-49615, CC-24215, L994, LS-48432, SBI-0206748.P001, AB0014996, TC-063579, WLN: T6N DNTJ D3VR DF& A- BT6NJ, AB00514057, FT-0602908, ST24037370, Azaperone, VETRANAL(TM), analytical standard, D02620, K-5140, AB00514057-06, AB00514057_07, 649A189, A810604, C-19900, L000791, I06-0254, J-010171, SR-05000001712-1, SR-05000001712-3, BRD-K45861246-001-05-0, BRD-K45861246-001-08-4, Azaperone, British Pharmacopoeia (BP) Reference Standard, {4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone}, 4'-Fluoro-4-[4-(2-pyridinyl)-1-piperazinyl]butyrophenone, Azaperone, European Pharmacopoeia (EP) Reference Standard, Azaperone, United States Pharmacopeia (USP) Reference Standard, Butyrophenone, {4'-fluoro-4-[4-(2-pyridyl)-1-piperazinyl]-}, 1-(4-fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanon, 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butznone, 1-(4-fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one, 1-Butanone, {1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-}, 1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone), 4 inverted exclamation mark -fluoro-4-(4-(2-pyridyl)-1-piperazinyl)-butyrophenon, 4 inverted exclamation marka-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone

ID: 2637

chemical graph of compound 2637



InChIKey: XTLJJHGQACAZMS-UHFFFAOYSA-N
SMILES: C1=C(NC(=CC1=O)C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8743
synonyms found at PubChem are:
CHELIDAMIC ACID, 138-60-3, 4-Hydroxypyridine-2,6-dicarboxylic acid, 4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid, 499-51-4, 4-HYDROXY-2,6-PYRIDINEDICARBOXYLIC ACID, 2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo-, Chelidamic acid hydrate, 4-oxo-1H-pyridine-2,6-dicarboxylic acid, CHEMBL252909, 2,6-Dicarboxy-4-hydroxypyridine, 1,4-Dihydro-4-oxopyridine-2,6-dicarboxylic acid, 2,6-Pyridinedicarboxylic acid, 4-hydroxy-, 4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid, chelidamic acid monohydrate, 4-oxohydropyridine-2,6-dicarboxylic acid, 1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate, NSC 3983, EINECS 205-335-8, Lopac-C-8011, UNII-1A59BH8SXE, AC1L1RM1, AC1Q6A8Z, 4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylicacid, Chelidamic acid, AldrichCPR, 1A59BH8SXE, Lopac0_000298, MLS000042771, SCHEMBL742928, 2, 1,4-dihydro-4-oxo-, CTK0H7778, CTK1D5079, DTXSID00160451, NSC3983, MolPort-000-882-841, MolPort-002-473-249, XTLJJHGQACAZMS-UHFFFAOYSA-N, HMS2439A21, HMS3260L18, KS-00000PB8, NSC-3983, ZINC6523946, Tox21_500298, ANW-70671, ANW-72230, BBL028110, BDBM50229870, SBB069057, STK793046, STL259705, AKOS000279986, AKOS003233475, CCG-204393, CS-W017065, DS-1684, LP00298, MCULE-2551574396, RL03828, NCGC00015270-01, NCGC00015270-02, NCGC00015270-03, NCGC00015270-04, NCGC00093748-01, NCGC00093748-02, NCGC00260983-01, 2,6-Pyridinedicarboxylicacid, 4-hydroxy-, AJ-62187, AN-43822, BP-12395, BR-54086, KB-39228, KB-48831, SC-20044, SC-23939, SMR000036248, AB0069409, AB0071625, AB1003610, DB-012857, DB-082252, KB-242253, ST2411586, TC-071277, TL8000881, 4CH-011022, C0821, EU-0100298, FT-0085071, FT-0623584, FT-0712040, ST50308105, A18191, C-1100, K-4485, 4-Oxo-1,4-dihydropyridine-2,6-dicarboxylicacid, 1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid, 138O603, AC-907/25014159, SR-01000075782, 2,6-Pyridinedicarboxylicacid, 1,4-dihydro-4-oxo-, 4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid #, I01-7863, J-400830, J-515530, S04-0004, SR-01000075782-1, 4-HYDROXYPYRIDINE-2,6-DICARBOXYLIC ACID HYDRATE, chelidamic acid (4-hydroxypyridine-2,6-dicarboxylic acid), 2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo- (8CI)(9CI), 1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate; 4-Hydroxypyridine-2,6-dicarboxylic acid

ID: 2638

chemical graph of compound 2638



InChIKey: XTPOZVLRZZIEBW-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CCNC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4397
synonyms found at PubChem are:
N6-2-(4-Aminophenyl)ethyladenosine, APNEA, [125I]APNEA, CHEMBL326958, [3H]N6-2-(4-Aminophenyl)ethyladenosine, 2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, D0A8EK, D0U6NZ, AC1L1I2P, AC1Q4Y3F, Lopac0_000118, GTPL417, GTPL462, ChEMBL_198532, SCHEMBL16585344, HMS3260G18, n-[2-(4-aminophenyl)ethyl]-9-pentofuranosyl-9h-purin-6-amine, Tox21_500118, BDBM50037785, CCG-204213, LP00118, NCGC00015017-02, NCGC00015017-03, NCGC00015017-04, NCGC00015017-05, NCGC00093612-01, NCGC00093612-02, NCGC00093612-03, NCGC00260803-01, A-202, EU-0100118, L000691, SR-01000075222, SR-01000075222-1, 2-(6-{[2-(4-aminophenyl)ethyl]amino}-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 2-{6-[2-(4-Amino-phenyl)-ethylamino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol

ID: 2639

chemical graph of compound 2639



InChIKey: XUARCIYIVXVTAE-ZAPOICBTSA-N
SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 92802
synonyms found at PubChem are:
Uvaol, 545-46-0, Urs-12-ene-3beta,28-diol, Urs-12-ene-3,28-diol, UNII-W599R31ROT, CHEMBL399873, W599R31ROT, CHEBI:67894, (3beta)-Urs-12-ene-3,28-diol, (3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-ol, EINECS 208-888-3, NSC 159627, D09OWE, AC1L3OV7, Uvaol, >=95%, 12-Ursen-3-beta,28-diol, SCHEMBL337913, BCBcMAP01_000233, MolPort-003-959-866, 3-beta,28-Dihydroxy-urs-12-ene, (3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14bR)-8a-Hydroxymethyl-4,4,6a,6b,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol, ZINC3978797, BDBM50218196, MFCD00009620, AKOS016036269, (3.beta.)-Urs-12-ene-3,28-diol, SMP1_000309, AN-45803, ST097776, Urs-12-ene-3,28-diol, (3.beta.), W2619, 545U460, SR-05000002219, SR-05000002219-2, (1S,7S,15S,16S,20S,2R,5R,10R,11R,17R)-20-(hydroxymethyl)-1,2,6,6,10,16,17-hept amethylpentacyclo[12.8.0.0<2,11>.0<5,10>.0<15,20>]docos-13-en-7-ol, (3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol

ID: 2640

chemical graph of compound 2640



InChIKey: XUBOMFCQGDBHNK-UHFFFAOYSA-N
SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5379
synonyms found at PubChem are:
Gatifloxacin, 112811-59-3, Tequin, Zymar, Gatiflo, Gatifloxacine, Gatiquin, Gatispan, Gatilox, Zymaxid, Gaity, AM-1155, AM 1155, gatifloxin, CG 5501, Gatifloxacin [USAN:INN], gatifloxacino, gatifloxacinum, BMS-206584, Bonoq, 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, BMS 206584-01, PD 135432, Gatifloxacin (TN), Gatifloxacin (INN), GTFX, gatifloxacin anhydrous, Zymer (TN), CHEMBL31, Gatifloxacin hydrate, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, Tequin in dextrose 5% in plastic container, CHEBI:5280, AM-1155 (*Sesquihydrate*), Gatifloxacin & Gamma Interferon, 160738-57-8, (+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, CG-5501, NCGC00068236-02, CPD000043336, PD135432, BMS-206584-01, PD-135432, Gatiflo (TN), Tequin (TN), G-2380, Zymar (TN), DSSTox_CID_25704, DSSTox_RID_81076, DSSTox_GSID_45704, Tymer, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid, 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, SMR000043336, CAS-112811-59-3, 1-cyclopropyl-6-fluoro-8-methoxy-7-, SR-01000610458, (3-methylpiperazin-1-yl)-4-oxo-1,4-, Gatifloxcin, Zymer, Tequin and Zymar, Gatifloxacin,(S), Kinome_3137, PubChem21048, Spectrum_001909, Gatiflo,Tequin and Zymar, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)- 4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, Spectrum2_000487, Spectrum3_000999, Spectrum4_001127, Spectrum5_001468, D03CQE, SCHEMBL22591, BSPBio_002697, KBioGR_001613, KBioSS_002448, MLS000040259, MLS000759493, MLS006011836, SPECTRUM1504272, SPBio_000353, Gatifloxacin Sesquihydrate,(S), AC1L1K82, DTXSID5045704, CTK6J4376, KBio2_002442, KBio2_005010, KBio2_007578, KBio3_001917, KS-00000IXR, MolPort-001-738-626, XUBOMFCQGDBHNK-UHFFFAOYSA-N, HMS1922J15, HMS2090K10, HMS2093G06, HMS2233D20, HMS3259P06, HMS3372J10, HMS3372J12, HMS3715N03, Pharmakon1600-01504272, ALBB-028535, BCP13408, RKL10068, ZX-AN079351, ZX-AP010622, Tox21_110984, BBL010485, BDBM50117914, BG0576, CCG-39529, CG5501, NSC758701, s1340, STK801620, AKOS004119932, AKOS016340697, Tox21_110984_1, AC-1944, API0002807, CS-1841, DB01044, Gatiflo,Tequin and Zymar, Gatifloxacin, KS-1066, MCULE-4557972261, NC00702, NSC-758701, RTR-002479, VA11838, NCGC00068236-03, NCGC00068236-04, NCGC00068236-05, NCGC00068236-06, NCGC00068236-07, NCGC00068236-08, NCGC00095126-01, NCGC00095126-02, NCGC00178525-01, AN-14480, AN-30562, AN-31062, BC204030, CC-34682, HY-10581, KB-71352, SAM001246715, SAM002589955, SC-12171, SBI-0206764.P001, AB0012064, AB1009302, AB2000056, AX8018671, DB-019145, LS-184402, TL8001438, TR-002479, FT-0082686, FT-0626635, FT-0631189, G0325, C07661, D08011, AB00171654-13, AB00171654-14, AB00171654_16, AB00171654_17, 811G593, A802657, C-21242, Gatifloxacin, Antibiotic for Culture Media Use Only, SR-01000610458-2, SR-01000610458-3, BRD-A74980173-001-02-8, BRD-A74980173-001-06-9, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-, 1-Cyclopropyl-6-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid, 1-Cyclopropyl-6-6-fluoro-1,4-dihydro-8-methoxy-7-(3methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoranyl-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxidanylidene-quinoline-3-carboxylic acid, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazino)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, 1-cyclopropyl-7-(3-methyl-1-piperazinyl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 3-Quinolinecarboxylic acid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, AC1NJHTG, MolPort-000-776-959, STL048947, AKOS005702286, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate, 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate

ID: 2641

chemical graph of compound 2641



InChIKey: XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES: C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3325
synonyms found at PubChem are:
Famotidina, Famotidinum, 76824-35-6, PEPCID, Brolin, Gastro, Famotin, DSSTox_CID_3039, 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide, DSSTox_RID_76846, DSSTox_GSID_23039, XUFQPHANEAPEMJ-UHFFFAOYSA-N, N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, Famotidine,(S), (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide, 3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine, NCGC00015446-05, CAS-76824-35-6, Pepcidin Pepcidine, Spectrum_001242, AC1L1FOE, Prestwick0_000104, Prestwick1_000104, Spectrum2_001036, Spectrum3_001427, Spectrum4_000408, KBioGR_000676, KBioSS_001722, DivK1c_000545, SPBio_001251, SPBio_002027, GTPL7074, DTXSID5023039, KBio1_000545, KBio2_001722, KBio2_004290, KBio2_006858, KBio3_002354, 2-[4-[2-(amino-sulfamoylimino-methyl)ethylsulfanylmethyl]-1,3-thiazol-2-yl]guanidine, 3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-4-YL)METHYLTHIO)-N-SULFAMOYLPROPANIMIDAMIDE, MolPort-006-167-663, NINDS_000545, HMS3372J17, HMS3393A07, HMS3604N21, HMS3655J17, Famotidine 1.0 mg/ml in Methanol, BCP22999, N inverted exclamation marka-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine, ZINC1530636, Tox21_110153, Tox21_301827, AKOS026750161, Tox21_110153_1, DB00927, LP00497, NCGC00018276-03, NCGC00021202-03, NCGC00255348-01, AB1009281, 89238-EP2275420A1, 89238-EP2305219A1, 89238-EP2305652A2, 95913-EP2303244A2, Z2196778897, N-sulfamoyl-3-[(2-guanidinothiazol-4-yl)methylthio]propionamidine, (Z)-3-(((2-((diaminomethylene)amino)thiazol-4-yl)methyl)thio)-N'-sulfamoylpropanimidamide, 3-[[[2-[(diaminomethylene) amino]-4-thiazolyl]methyl]thio]-n2-sulfamoyl propionamidine, 3-{[(2-carbamimidamido-1,3-thiazol-4-yl)methyl]sulfanyl}-N-sulfamoylpropanimidamide, N -[Aminosulfonyl]-3-[2-[diaminomethyleneamino]-4-thiazolyl)methylthio]-propanamidine, 3-[[[2-[( paragraph signthorn degrees +/->>uNC(1/4)x>>u)-4-acsso>>u](1/4)x>>u]Ao u]-N- degrees +/->>Co pound+/-uess. A feminineIae paragraph sign inverted exclamation mark, N'-(aminosulfonyl)-3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]propanimidamide, Pepcid Ac (geltab), UNII-5QZO15J2Z8, HSDB 3572, Major heartburn relief, CHEMBL902, 5QZO15J2Z8, Famotidine [USAN:USP:INN:BAN:JAN], AC1NS4DZ, Famotidine preservative free (pharmacy bulk), Spectrum5_001357, BSPBio_003134, SPECTRUM1501003, HMS501L07, HMS1921B05, HMS2092O18, Pharmakon1600-01501003, Propanimidamide, 3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)-, Propanimidamide, N'-(aminosulfonyl)-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-, BDBM50036754, CCG-40241, NSC757810, STL454342, NSC-757810, IDI1_000545, NCGC00094885-01, NCGC00094885-02, NCGC00094885-03, 108885-67-2 (HCl), AB00052192_02, SR-05000001558, SR-05000001558-1, BRD-K00673382-001-05-6, BRD-K00673382-001-07-2, 3-(2-Guanidino-thiazol-4-ylmethylsulfanyl)-N-sulfonylamino-propionamidine, (1E)-3-{[(2-carbamimidamido-1,3-thiazol-4-yl)methyl]sulfanyl}-N'-sulfamoylpropanimidamide, N-sulfomoyl-3-(2-Guanidino-2H-1lambda*4*-thiazol-4-ylmethylsulfanyl)-propionamidine, (1Z)-N''-(aminosulfonyl)-3-[({2-[(diaminomethylene)amino]-1,3-thiazol-4-yl}methyl)thio]propanimidamide, (1Z)-N''-(aminosulfonyl)-3-[({2-[(diaminomethylene)amino]-1,3-thiazol-4-yl}methyl)thio]propanimidamide (Famotidine), N''-(aminosulfonyl)-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propanimidamide, famotidine, Pepcid AC, Apogastine, Amfamox, Antodine, Bestidine, Digervin, Dispromil, Famodil, Gastridin, Pepcidine, Pepdine, Quamatel, Cepal, Fluxid, Gaster, Pepdul, Pepcid RPD, Gastrodomina, Blocacid, Confobos, Dispronil, Fagastine, Famodine, Famogard, Famopsin, Famovane, Famulcer, Farmotex, Ferotine, Gastridan, Gastrion, Gastrofam, Gastropen, Gastrosidin, Huberdina, Ingastri, Neocidine, Nulceran, Nulcerin, Pepcidin, Pepcidina, Pepfamin, Peptidin, Peptifam, Renapepsa, Restadin, Rubacina, Supertidine, Ulceprax, Ulgarine, Vagostal, Whitidin, Cronol, Cuantin, Dipsin, Duovel, Durater, Evatin, Fadine, Famocid, Famodar, Famodin, Famonit, Famosan, Famotal, Famotep, Famowal, Famoxal, Famtac, Fanobel, Fanosin, Fibonel, Fudone, Invigan, Lecedil, Mensoma, Midefam, Motiax, Muclox, Nevofam, Notidin, Panalba, Pepdif, Peptan, Pepzan, Purifam, Quamtel, Rogasti, Sigafam, Tairal, Tipodex, Topcid, Ulcatif, Ulcofam, Ulfagel, Ulfamid, Ulfinol, Weimok, Yamarin, Dinul, Fadin, Fadyn, Famos, Famox, Fanox, Ganor, Hacip, Logos, Mosul, Tamin, Ulfam, Famo, Novo-Famotidine, Apo-Famotidine, Nu-Famotidine, Pepcidin Rapitab, Sedanium-R, Mylanta AR, Dibrit 40, Famotidinum [Latin], Pepcidac, Famotidina [Spanish], MK-208, H2 Bloc, MK 208, YM 11170, YM-11170, Pepcid AC Gelcaps, Pepcid (TN), PEPCID PRESERVATIVE FREE, PEPCID COMPLETE, C8H15N7O2S3, Famotidine [USAN:BAN:INN:JAN], FAMOTIDINE PRESERVATIVE FREE, 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N-sulfamoylpropanimidamide, CHEBI:4975, L 643341, PEPCID PRESERVATIVE FREE IN PLASTIC CONTAINER, N'-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine, FAMOTIDINE PRESERVATIVE FREE IN PLASTIC CONTAINER, HS-0054, YM-1170, F0530, F 6889, XUFQPHANEAPEMJ-UHFFFAOYSA-, 3-(((2-((Diaminomethylene)amino)thiazol-4-yl)methyl)thio)-N'-sulfamoylpropanimidamide, 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpro, Propanimidamide, 3-[[[2-[aminoiminomethyl)amino]-4-thiazoyl]methyl]thio]-N-(aminosulfonyl), (1Z)-3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide, (1Z)-N'-(aminosulfonyl)-3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)thio]propanimidamide, SMR000058961, SR-05000001440, agufam, PepcidRPD, 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide, Pepcidine (TN), 3-[((2-[(DIAMINOMETHYLIDENE)AMINO]-1,3-THIAZOL-4-YL)METHYL)SULFANYL]-N-SULFAMOYLPROPANIMIDAMIDE, InChI=1/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14), Prestwick_212, Famotidine (Pepcid), Fluxid (TN), AC1NWASH, Prestwick2_000104, Prestwick3_000104, Lopac-F-6889, SCHEMBL972, SCHEMBL974, D0K0OZ, D0S7VH, Lopac0_000497, BSPBio_000088, MLS000028583, MLS000758205, MLS001423994, BIDD:GT0759, AC1Q50E0, AC1Q50E1, BPBio1_000098, Famotidine (JP17/USP/INN), BDBM22891, cid_5702160, MolPort-002-557-620, MolPort-003-941-395, MolPort-006-069-255, HMS1568E10, HMS2051A07, HMS2089I12, HMS2095E10, HMS2231I22, HMS3261D15, HMS3712E10, HY-B0377, Tox21_500497, BDBM50103514, KM1798, PDSP1_000398, PDSP2_000396, s2078, STK527689, AKOS005460541, AKOS015994617, AKOS030573443, AB03031, CCG-100767, CCG-220104, CCG-221801, CS-2445, MCULE-1972636463, NC00017, NCGC00015446-01, NCGC00015446-02, NCGC00015446-03, NCGC00015446-04, NCGC00015446-06, NCGC00018276-01, NCGC00018276-02, NCGC00093899-01, NCGC00093899-02, NCGC00093899-03, NCGC00188952-01, NCGC00261182-01, AC-11713, BC203224, CPD000058961, K328, SAM001247033, SBI-0050481.P003, LS-121117, TL8005267, EU-0100497, ST51001070, D00318, AB00383032_11, 824F356, L003830, L013386, SR-01000075883, SR-01000075883-1, SR-05000001440-1, SR-05000001440-2, Famotidine, European Pharmacopoeia (EP) Reference Standard, Famotidine, United States Pharmacopeia (USP) Reference Standard, 3-(((2-guanidinothiazol-4-yl)methyl)thio)-N-sulfamoylpropanimidamide, 3-[(2-guanidinothiazol-4-yl)methylsulfanyl]-N-sulfamoyl-propanamidine, Famotidine, Pharmaceutical Secondary Standard; Certified Reference Material, 3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-5-YL)METHYLTHIO)-N'-SULFAMOYLPROPANIMIDAMIDE, 3-[2-(diaminomethyleneamino] thiazol-4-ylmethylthio]-N-sulphamoyl propionamidine, Famotidine for system suitability, European Pharmacopoeia (EP) Reference Standard, N'-[Aminosulfonyl]-3-[2-[diaminomethyleneamino]-4-thiazolyl)methylthio]-propanamidine, N-(Aminosulfonyl)-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide, (1Z)-2-amino-4-{[2-(2,2-diamino-1-azavinyl)(1,3-thiazol-4-yl)]methylthio}-1-az abut-1-enesulfonamide, (Z)-3-((2-(DIAMINOMETHYLENEAMINO)THIAZOL-4-YL)METHYLTHIO)-N'-SULFAMOYLPROPANIMIDAMIDE, 1-AMINO-3-[[[[2-[(DIAMINOMETHYLENE)AMINO]-4-THIAZOLYL]METHYL]THIO]PROPYLIDENE]SULFAMIDE, 3-[({2-[(Diaminomethylene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide, 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N''-sulfamoylpropanimidamide, 3-[[[2-[(AMINOIMINOMETHYL)AMINO]-4-THIAZOLYL]METHYL]THIO]-N-(AMINOSULFONYL)-PROPANIMIDAMIDE

ID: 2642

chemical graph of compound 2642



InChIKey: XUKPZPRDNPUAJY-JEDNCBNOSA-N
SMILES: CC(=O)O.CSC(=NCCC[C@@H](C(=O)O)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957614
synonyms found at PubChem are:
S-Methyl-L-thiocitrulline acetate salt, S-Methyl-L-thiocitrulline acetate, S-Me-TC;SMTC, 156719-41-4, 174063-92-4, SR-01000075480, EU-0100777, SCHEMBL1320099, CHEMBL1256475, CTK8G3124, DTXSID70474693, HMS3262K16, Tox21_500777, CCG-222081, LP00777, NCGC00094114-01, NCGC00261462-01, M 5171, N5-[Imino(methylthio)methyl]-L-ornithine acetate, J-010964, SR-01000075480-1, S-Methyl-L-thiocitrulline acetate salt, >=98% (TLC)

ID: 2643

chemical graph of compound 2643



InChIKey: XUXBOSSCMLZGTA-UHFFFAOYSA-N
SMILES: CC1(C=CC2=C(C=CC(=C2O1)C(=O)CC(=O)O)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 795044
synonyms found at PubChem are:
URSINOIC ACID, 3-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxopropanoic acid, 30265-59-9, SR-01000388393, KBio2_004592, URSINIC ACID, Spectrum_001544, SpecPlus_000950, AC1LGHS0, Spectrum2_000733, Spectrum3_001646, Spectrum4_001669, Spectrum5_000577, AC1Q49IH, AC1Q5V7D, Oprea1_569596, Oprea1_707351, BSPBio_003371, KBioGR_002197, KBioSS_002024, MLS000105991, DivK1c_007046, SPECTRUM1504167, SPBio_000686, CHEMBL1609777, KBio1_001990, KBio2_002024, KBio2_007160, KBio3_002591, CHEBI:105327, MolPort-001-802-949, HMS2414E18, ZINC298413, 2h-1-benzopyran-8-propanoic acid, 5-methoxy-2,2-dimethyl-|A-oxo-, CCG-40137, STK039163, AKOS000546855, MCULE-6966159864, SDCCGMLS-0016268.P002, NCGC00074767-04, BAS 00015475, SMR000102965, ST50000040, X6843, SR-01000388393-1, SR-01000388393-3, BRD-K92405402-001-02-5, BRD-K92405402-001-11-6, 3-(5-methoxy-2,2-dimethylchromen-8-yl)-3-oxopropanoic acid, 3-(5-methoxy-2,2-dimethyl(2H-chromen-8-yl))-3-oxopropanoic acid, 3-(5-Methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-oxo-propionic acid

ID: 2644

chemical graph of compound 2644



InChIKey: XUYJLQHKOGNDPB-UHFFFAOYSA-N
SMILES: C(C(=O)O)P(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 546
synonyms found at PubChem are:
Phosphonoacetic acid, Fosfonet, phosphonoacetate, 4408-78-0, Acetic acid, phosphono-, 2-phosphonoacetic acid, Fosfonet sodium, Phosphonacetic acid, Carboxymethanephosphonic acid, Fosfonoacetic acid, Disodium phosphonoacetate, CHEBI:15732, UNII-N919E46723, EINECS 224-558-1, Lopac-P-6909, NSC 18205, BRN 1764355, MLS000069393, Abbott 38642, XUYJLQHKOGNDPB-UHFFFAOYSA-N, Disodium carboxymethylphosphonate, NCGC00014361-03, SMR000058341, Disodium phosphonoacetate monohydrate, N919E46723, NSC138745, DSSTox_CID_25107, DSSTox_RID_80674, DSSTox_GSID_45107, PAE, Abbott-38642, CAS-4408-78-0, NSC-138745, 36983-81-0, Fosfonoacetate, Phosphonacetate, Carboxymethanephosphonate, 1ew8, 2-phosphonoethanoic acid, ACMC-1AKGI, AC1Q5WSF, Opera_ID_1619, bmse000660, AC1L19HA, Phosphonoacetic acid, 98%, NCIStruc1_000084, NCIStruc2_000084, Lopac0_000991, SCHEMBL15612, C2H5O5P, 4-04-00-03612 (Beilstein Handbook Reference), CHEMBL50300, DTXSID2045107, CTK3J2395, XUYJLQHKOGNDPB-UHFFFAOYSA-, HMS2234F14, HMS3263G03, HMS3371G15, Phosphonoacetic acid, 98% 10g, NSC18205, ZINC3869741, ZX-AT022712, Tox21_110045, Tox21_500991, BDBM50008089, CCG-38040, FCH963793, NCGC00014361, NCI138745, NSC-18205, STK372961, AKOS005447286, Fosfonet Sodium (phosphonoacetic acid), Tox21_110045_1, ACM4408780, DB02823, ING0004650, LP00991, NCGC00014361-02, NCGC00014361-04, NCGC00014361-05, NCGC00014361-06, NCGC00014361-07, NCGC00014361-08, NCGC00094288-01, NCGC00094288-02, NCGC00094288-03, NCGC00261676-01, CC-33755, LS-12796, NCI60_000870, SC-48625, DB-009800, RT-000589, EU-0100991, FT-0635275, C05682, P 6909, A826485, C-01928, SR-01000076075, I04-9942, SR-01000076075-1, 7057FCB7-1B5A-4B59-B5AC-380E86F98C9D, Phosphonoacetic acid, TraceCERT(R), 31P-qNMR Standard, InChI=1/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7), 7230-09-3

ID: 2645

chemical graph of compound 2645



InChIKey: XVZBPRMCKGPWFX-BZNPZCIMSA-N
SMILES: N(CC#C)1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Désiré" "A Mingot" "S Thibaudeau" "F Becq" "Y Blériot" "V Cendret" "A Kato" "M Forcella" "I Adachi" "C Norez" "T Legigan" "P Parenti" "J Bertrand"


CID is 101518114
synonyms found at PubChem are:
1,5-Dideoxy-1,5-(propargylimino)-D-glucitol

ID: 2646

chemical graph of compound 2646



InChIKey: XWHHYOYVRVGJJY-QMMMGPOBSA-N
SMILES: C1=CC(=CC=C1C[C@@H](C(=O)O)N)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 716312
synonyms found at PubChem are:
4-FLUORO-L-PHENYLALANINE, 1132-68-9, p-Fluoro-L-phenylalanine, L-4-Fluorophenylalanine, (s)-4-fluorophenylalanine, h-phe(4-f)-oh, (s)-2-amino-3-(4-fluorophenyl)propanoic acid, (2S)-2-amino-3-(4-fluorophenyl)propanoic acid, UNII-E2K2VDK6KK, l-4-fluorophe, L-Phenylalanine, 4-fluoro-, S-(-)-p-Fluorophenylalanine, Phenylalanine, 4-fluoro-, E2K2VDK6KK, CHEBI:44909, XWHHYOYVRVGJJY-QMMMGPOBSA-N, h-p-fluoro-phe-oh, (S)-2-Amino-3-(4-fluorophenyl)propionic Acid, l-4-fluoro phenylalanine, l-4-fluoro-phenyl-alanine, 3-(4-fluorophenyl)-l-alanine, PFF, 4-fluor-l-phenylalanin, (s)-2-amino-3-(4-fluoro-phenyl)-propionic acid, F-Phe, h-phe(p-f)-oh, p-fluoro-phenylalanine, h-l-phe(4-f)-oh, AC1LEQDX, Para-Fluorophenylalanine, rarechem bk pt 0031, 4-fluorophenyl-L-alanine, L-4-F-Phe-OH, AC1Q4NO1, Lopac0_000545, SCHEMBL44071, L-3-(4-Fluorophenyl)alanine, (S)-b-(p-fluorophenyl)alanine, Jsp001032, CHEMBL1235242, CHEBI:10625, CTK2F1219, MolPort-001-771-502, HMS3261N11, ZINC113778, KS-00000AN7, Tox21_500545, ANW-16574, CF-338, SBB063698, AKOS010367425, AKOS015853512, AC-5833, CCG-204635, CS-W002291, LP00545, RP24396, RTR-002528, NCGC00093933-01, NCGC00093933-02, NCGC00093933-03, NCGC00261230-01, AJ-11452, AS-12890, BR-25301, KB-38849, KB-63573, SC-10780, SC-10782, SY030990, 4-Fluoro-L-phenylalanine; H-Phe(4-F)-OH, AB0012559, AB1007200, DB-016873, ST2408334, TL8000395, TR-002528, AM20060487, EU-0100545, F0274, FT-0613670, F 4646, M-2552, (2S)-2-amino-3-(4-fluorophenyl)propionic acid, (2S)-2-azanyl-3-(4-fluorophenyl)propanoic acid, 132F689, SR-01000075877, I01-5171, I01-7221, I01-7222, J-300403, J-650273, SR-01000075877-1, UNII-42T8578M1E component XWHHYOYVRVGJJY-QMMMGPOBSA-N, 3f3c, AC1OBS7W, CJ-00825, ZB003832, (2S)-2-azaniumyl-3-(4-fluorophenyl)propanoate

ID: 2647

chemical graph of compound 2647



InChIKey: XWIHRGFIPXWGEF-UHFFFAOYSA-N
SMILES: CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 36708
synonyms found at PubChem are:
PROPAFENONE HYDROCHLORIDE, 34183-22-7, Propafenone HCl, Rythmol, Rytmonorm, Arythmol, Pronon, Baxarytmon, Fenoprain, Rythmol SR, Rhythmonorm, Propafenon hydrochlorid, SA 79, Propafenone (hydrochloride), Propafenon hydrochlorid [German], EINECS 251-867-9, WZ 884, 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride, 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride, MLS000069682, CHEBI:8466, SMR000058493, 2'-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone hydrochloride, 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride, C21H28ClNO3, 1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride, Propiophenone, 2'-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride, SR-01000000192, 2'-[2-Hydroxy-3-(propylamino)propoxy]-3-phenylpropiophenone Hydrochloride, Propafenone, HCl, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride, Prestwick_831, Rythmol (TN), Propafenone hydrochloride [USAN:JAN], ACMC-20cvw7, ACMC-20cvw9, Propafenone hydrochloride [USAN:USP:JAN], AC1Q3DVX, Opera_ID_1835, AC1L1W9R, AC1Q39QV, SCHEMBL41412, MLS001148185, MLS002222267, SPECTRUM1503935, CHEMBL1201063, CTK6E5427, HY-B0432A, MolPort-003-666-514, XWIHRGFIPXWGEF-UHFFFAOYSA-N, HMS1569D19, HMS1922M16, Pharmakon1600-01503935, 1-Propanone,1-[2-[(2R)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride(9CI), 1-Propanone,1-[2-[(2S)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride(1:1), 54063-53-5 (Parent), BCP28548, KS-000000SR, Tox21_500919, CCG-39061, MFCD00079243, NSC758640, AKOS008901409, Propafenone hydrochloride (JP17/USP), AN-6428, CS-2538, KS-5030, LP00919, MCULE-5193630487, NSC-758640, NCGC00094230-01, NCGC00094230-02, NCGC00094230-03, NCGC00094230-04, NCGC00094230-05, NCGC00261604-01, AC-11360, CPD000058493, SAM002548929, SC-47004, AB0011670, LS-125353, EU-0100919, FT-0630579, P2301, EN300-51034, D00640, J10361, K-7828, P 4670, 183P227, A822113, J-019481, SR-01000000192-2, SR-01000000192-6, Z802671518, 1-(2-[2-Hydroxy-3-(propylamino)propoxy]phenyl)-3-phenyl-1propanone, 2'-(2-hydroxy-3-propylaminopropoxy)-3-phenylpropiophenone hydrochloride, Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-propan-1-one hydrochloride, 1-[2-[2-oxidanyl-3-(propylamino)propoxy]phenyl]-3-phenyl-propan-1-one hydrochloride, 2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]-N-propylpropan-1-aminium chloride, Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard, 163858-56-8, AC1LCWGM, AKOS026749966, hydron; 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one; chloride

ID: 2648

chemical graph of compound 2648



InChIKey: XWLCIDLCEZAOEY-UHFFFAOYSA-N
SMILES: CCCN(CCC1=CC=CC=C1)C2CCC3=C(C2)C=CC=C3O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957671
synonyms found at PubChem are:
(+/-)-PPHT hydrochloride, 71787-90-1, N-0434, PPHT hydrochloride, (y)-PPHT hydrochloride, (?)-PPHT hydrochloride, EU-0101006, MLS000860001, CHEMBL1256754, CTK8G7698, DTXSID30474699, MolPort-003-959-145, Tox21_501006, MFCD00055157, AKOS024418760, CCG-222310, LP01006, MCULE-3742110977, NCGC00094300-01, NCGC00261691-01, SMR000326860, NCG-C00094300-01, ( inverted question mark)-PPHT hydrochloride, FT-0757152, P-105, ( inverted exclamation markA)-PPHT hydrochloride, SR-01000075394, SR-01000075394-1, (+/-)-PPHT hydrochloride, >=98% (HPLC), solid, (+/-)-PPHT HYDROCHLORIDE (N-0434) POTENTD2 DOPAMINE RE, (+/-)-2-(N-Phenethyl-N-propyl)amino-5-hydroxytetralin hydrochloride, ( inverted exclamation markA)-2-(N-Phenethyl-N-propyl)amino-5-hydroxytetralin hydrochloride, ( inverted question mark)-2-(N-Phenylethyl)-N-propyl)amino-5-hydroxytetralin hydrochloride, 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[(2-phenylethyl)propylamino]-, hydrochloride

ID: 2649

chemical graph of compound 2649



InChIKey: XWQWACGTGFICFO-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C1(CCCC1)C2=CC=C(C=C2)[N+](=O)[O-].Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 25102587
synonyms found at PubChem are:
Nitrocaramiphen hydrochloride, 98636-73-8, CHEMBL543382, SR-01000597752, MLS002154082, SCHEMBL5302449, CTK8G1898, MolPort-003-983-649, HMS1571E03, BN0384, AKOS024458295, CCG-220981, MCULE-6038639819, SMR001233391, B6311, SR-01000597752-1, SR-01000597752-3, 2-Diethylaminoethyl 1-(4-nitrophenyl)cyclopentanecarboxylate hydrochloride

ID: 2650

chemical graph of compound 2650



InChIKey: XWXYUMMDTVBTOU-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4493
synonyms found at PubChem are:
nilutamide, 63612-50-0, Anandron, Nilandron, Nilandrone, Nilutamida, Nilutamidum, 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione, Nilutamidum [Latin], Nilutamida [Spanish], RU-23908, 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione, Nilutamide [USAN:INN:BAN], RU 23908, Nilandron (TN), RU 23908-10, Nilutamide [USAN:BAN:INN], UNII-51G6I8B902, 5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin, C12H10F3N3O4, Nilutamide (USAN/INN), BRN 0841906, CHEMBL1274, CHEBI:7573, XWXYUMMDTVBTOU-UHFFFAOYSA-N, 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione, 5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione, 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione, 51G6I8B902, NCGC00015754-08, CAS-63612-50-0, N 8534, 2,4-IMIDAZOLIDINEDIONE, 5,5-DIMETHYL-3-(4-NITRO-3-(TRIFLUOROMETHYL)PHENYL)-, DSSTox_CID_14165, DSSTox_RID_79118, DSSTox_GSID_34165, 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-1,3-diazolidine-2,4-dione, SR-01000076034, Nilutamide, solid, Anandron (TN), PubChem19359, Spectrum_001625, Tocris-1759, SpecPlus_000902, AC1L1IAG, Prestwick0_000928, Prestwick1_000928, Prestwick2_000928, Prestwick3_000928, Spectrum2_001973, Spectrum3_001633, Spectrum4_000600, Spectrum5_001512, Lopac-N-8534, D0SN9T, Aventis Brand of Nilutamide, Hoechst Brand of Nilutamide, BIDD:PXR0177, Lopac0_000879, SCHEMBL12670, BSPBio_000836, BSPBio_003325, KBioGR_001100, KBioSS_002105, MLS002154066, BIDD:GT0683, DivK1c_006998, SPECTRUM1504152, SPBio_002125, SPBio_003015, BPBio1_000920, GTPL2864, DTXSID3034165, CTK8B7740, KBio1_001942, KBio2_002105, KBio2_004673, KBio2_007241, KBio3_002545, MolPort-003-666-533, MolPort-005-975-300, BCPP000148, HMS1570J18, HMS1922F03, HMS2093A10, HMS2097J18, HMS2230E03, HMS3262P19, HMS3268C18, HMS3369I02, HMS3714J18, Pharmakon1600-01504152, Aventis Behring Brand of Nilutamide, BCP26617, ZINC3874498, Tox21 110213, Tox21_110213, Tox21_301589, Tox21_500879, ANW-58327, BDBM50135912, CCG-39427, MFCD00864670, NSC758683, SBB067297, STK633161, 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)- 2,4-imidazolidinedione, AKOS005565152, AKOS025147305, Tox21_110213_1, AC-5260, API0003576, BCP9000990, DB00665, LP00879, MCULE-3215206804, NSC-758683, NCGC00015754-01, NCGC00015754-02, NCGC00015754-03, NCGC00015754-04, NCGC00015754-05, NCGC00015754-06, NCGC00015754-07, NCGC00015754-09, NCGC00015754-10, NCGC00015754-11, NCGC00015754-12, NCGC00015754-15, NCGC00015754-16, NCGC00025280-01, NCGC00025280-02, NCGC00025280-03, NCGC00025280-04, NCGC00025280-05, NCGC00025280-06, NCGC00025280-07, NCGC00025280-08, NCGC00255271-01, NCGC00261564-01, 4CA-0906, AJ-46401, AN-11150, AS-14123, CC-32857, K002, KB-58335, LS-79181, SC-74493, SMR001233381, ST075550, SBI-0050854.P003, AB0013969, AX8041902, TC-030602, AB00053180, EU-0100879, FT-0080574, FT-0630740, C08164, D00965, AB00053180_07, 612N500, A834440, C-19507, L000759, I14-2740, SR-01000076034-1, SR-01000076034-3, SR-01000076034-5, SR-01000076034-6, SR-01000076034-9, BRD-K23566484-001-05-2, BRD-K23566484-001-09-4, Z2417927201, Nilutamide, European Pharmacopoeia (EP) Reference Standard, 1-(3'-trifluoromethyl-4'-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione, 1-(3'-trifluoromethyl-4'-nitrophenyl)4,4-dimethyl-imidazoline-2,5-dione, 1-(3'-trifluoromethyl-4'nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione, 1-(3'trifluoromethyl-4'-nitropheyl)-4,4-dimethyl-imidazoline-2,5-dione, 1-(3-'trifluoromethyl-4'-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione, 1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl imidazolidine-2,5-dione, 1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl-imidazolidine-2,5-dione, 1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl-imidazoline-2,5-dione, 1-(3-trifluoromethyl-4-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione, 3-(3-(trifluoromethyl)-4-nitrophenyl)-5,5-dimethylimidazolidine-2,4-dione, 5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)-phenyl)imidazolidine-2,4-dione, 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-imidazolidine-2,4-dione

ID: 2651

chemical graph of compound 2651



InChIKey: XXPDBLUZJRXNNZ-UHFFFAOYSA-N
SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6014
synonyms found at PubChem are:
PROMETHAZINE HYDROCHLORIDE, 58-33-3, Phenergan, Promethazine Hcl, Fenergan, N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride, Diprasine, Farganesse, Fellozine, Pipolfen, Pipolphen, Ganphen, Plletia, Diprazin, Romergan, Promethazine chloride, Promethiazin, Allerfen, Duplamin, Frinova, Goodnight, Hibechin, Histantil, Kinetosin, Phenadoz, Phencen, Primine, Promantine, Promine, Proneurin, Soporil, Bonnox, Closin, Dorme, Prome, Prometh Fortis, Prometh Plain, Eusedon Mono, Phenergan Fortis, Promethazine.HCl, PMS Promethazine, V GAN, Mymethazine Fortis, Promethazine Plain, Anergan 25, Anergan 50, Promethazine (hydrochloride), Promethazine monohydrochloride, PHENERGAN PLAIN, Promethiazin [German], ZIPAN-50, HL 8700, CCRIS 5873, Phenergan hydrochloride, N-(2-Dimethylaminopropyl-1)phenothiazine hydrochloride, EINECS 200-375-2, N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine hydrochloride, NSC 231688, 10-(3-Dimethylaminoisopropyl)phenothiazine hydrochloride, 10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride, 3277 R.P., MLS000069398, 10-(2-Dimethylamino-1-propyl)phenothiazine hydrochloride, CHEBI:8462, Sominex, 10-(2-Dimethylaminopropyl)phenothiazine hydrochloride, RP 3389, 10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride, CPD000058379, SMR000058379, Phenergan (TN), Phenothiazine, 10-(2-(dimethylamino)-propyl)-, hydrochloride, Promethegan (TN), (+-)-10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride, DSSTox_CID_1192, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride, DSSTox_RID_76002, DSSTox_GSID_21192, N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine hydrochloride, Phenothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride, (+-)-, Vallgerine, Phergan, N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride, prim ine, SR-01000002993, Promethazine hydrochloride [JAN], component of Mepergan, Promethazine hydrochloride [USP:JAN], PromethazineHydrochloride, Promethazine hydrochlorine, CAS-58-33-3, Opera_ID_1745, AC1L1LM3, SCHEMBL41904, MLS001074184, MLS002548850, SPECTRUM1500510, Promethazine Hydrochloride,(S), CHEMBL1200750, DTXSID3021192, CTK8G2592, BBC/878, MolPort-003-666-272, XXPDBLUZJRXNNZ-UHFFFAOYSA-N, (+/-)-Promethazine Hydrochloride, HMS1570B18, HMS1920L16, LS-40, Pharmakon1600-01500510, HY-B0781, Tox21_202264, Tox21_302878, Tox21_500899, MFCD00012652, NSC231688, NSC757301, s4293, AKOS016339657, API0003942, CCG-207895, CS-3543, KS-1385, LP00899, MCULE-6615710182, NC00471, NSC-231688, NSC-757301, Promethazine hydrochloride (JP17/USP), TRA0003095, KS-0000129F, NCGC00089735-04, NCGC00094215-01, NCGC00094215-02, NCGC00094215-03, NCGC00094215-04, NCGC00094215-05, NCGC00256588-01, NCGC00259813-01, NCGC00261584-01, 3277 R.P, AC-12482, AN-41751, H509, SAM002264636, SC-19551, AB0013086, AX8055660, EU-0100899, FT-0631258, P2029, ST24048193, ST51015100, D00480, J10089, P 4651, WLN: T C666 BN ISJ B1Y1&N1&1 &GH, A831833, SR-01000002993-2, SR-01000002993-7, W-105399, 10-(3-dimethylaminoisoprop yl)phenothiazine hydrochloride, F0138-3355, N-(2-dimethylaminoprop-1-yl)phenothiazine hydrochloride, Z1259273234, N,N-dimethyl-1-(10-phenothiazinyl)-2-propanamine hydrochloride, N-(2'-Dimethylamino-2'-methylaethyl)-phenothiazin hydrochlorid, N-(2'-dimethylamino-2'-methylethyl)phenothiazine hydrochlor ide, N-(2'-dimethylamino-2'-methylethyl)phenothiazine hydrochloride, N-(2'-Dimethylamino-2-methylethyl)phenothiazine hydrochloride, Promethazine hydrochloride, VETRANAL(TM), analytical standard, (2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine Hydrochloride, PROMETHAZINE HYDROCHLORIDE (SEE ALSO PROMETHAZINE 60-87-7), 10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl-, monohydrochloride, DIMETHYL[1-(10H-PHENOTHIAZIN-10-YL)PROPAN-2-YL]AMINE HYDROCHLORIDE, N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine monohydrochloride, Promethazine Hydrochloride 1.0 mg/ml in Dimethyl Sulfoxide (as free base), Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Promethazine hydrochloride, vial of 25 mg, certified reference material, 10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl-, hydrochloride (1:1), 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, hydrochloride (1:1), Promethazine for peak identification, European Pharmacopoeia (EP) Reference Standard, Promethazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Promethazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 16639-38-6, 88208-28-0, AC1LAODW, dimethyl(1-phenothiazin-10-ylpropan-2-yl)azanium chloride, Promethazine HCI, AC1LCW9R, AKOS015914197, (+/-)-10-[2-(Dimethylamino)propyl]phenothiazine HCl, N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine; hydron; chloride, SCHEMBL13257618

ID: 2652

chemical graph of compound 2652



InChIKey: XXRMYXBSBOVVBH-UHFFFAOYSA-N
SMILES: CC(C[N+](C)(C)C)OC(=O)N.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11548
synonyms found at PubChem are:
Bethanechol chloride, 590-63-6, Urecholine, Myocholine, Besacholine, Mechotane, Mechothane, Mecothane, Myotonachol, Myotonine, Mictone, Uro-Carb, Urecholine chloride, Mictrol, Duvoid, Muscaran, Carbamylmethylcholine chloride, Carbamyl-beta-methylcholine chloride, Bethaine choline chloride, Bethanechol (chloride), Trimethyl(2-carbamoyloxypropyl)ammonium chloride, (2-Hydroxypropyl)trimethylammonium chloride carbamate, 2-Carbamoyloxypropyltrimethylammonium chloride, beta-Methylcholine chloride urethan, EINECS 209-686-8, beta-Methyl carbachol chloride, NSC 30783, 2-((Aminocarbonyl)oxy)-N,N,N-trimethyl-1-propanaminium chloride, Carbaminoyl, beta-methylcholine chloride, MLS000028675, 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium chloride, CHEBI:3085, 1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride, SMR000058680, Urecholine (TN), 1-Propanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride, DSSTox_CID_2676, EN300-51035, 2-carbamoyloxypropyl(trimethyl)ammonium chloride, (2-Carbamoyloxypropyl)trimethylammonium chloride, DSSTox_RID_76686, DSSTox_GSID_22676, C7H16N2O2, (+-)-(2-Hydroxypropyl)trimethylammonium chloride carbamate, AMMONIUM, (2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, CARBAMATE, 1-Propanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride, (+-)-, CPD000058680, SR-01000000282, NCGC00163217-01, 2-carbamoyloxypropyl(trimethyl)azanium;chloride, 1-Propanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride (1:1), 1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1), Bethanechol chloride [BAN:JAN], Bethanechol chloride [USP:BAN:JAN], Bethanechol(chloride), AC1Q1RXM, regid855684, Opera_ID_1125, CAS-590-63-6, AC1L1XL7, CHEMBL1768, SCHEMBL37393, Ammonium, chloride, carbamate, MLS001148071, MLS006011984, SPECTRUM1500146, 674-38-4 (Parent), DTXSID2022676, .beta.-Methyl carbachol chloride, CTK4E5567, HMS500I21, HY-B0406A, Carbamyl-beta-methylcholine chlori, MolPort-003-666-134, Bethanechol chloride (JP17/USP), carbamyl-|A-methylcholine chloride, HMS1571G08, HMS1920G19, HMS2091M19, HMS2098G08, HMS2232D09, HMS3259L15, HMS3260N10, HMS3374D01, HMS3656G21, HMS3715G08, Pharmakon1600-01500146, NSC30783, Tox21_112028, Tox21_500304, BG0106, Carbamyl- beta-methylcholine chloride, CCG-38936, KM0280, MFCD00055224, NSC-30783, NSC755913, s2455, SBB070369, .beta.-Methylcholine chloride urethan, AKOS006230324, Tox21_112028_1, Carbamyl-beta-methylcholine chloride.cd, CS-2506, LP00304, MCULE-3425585639, NC00660, NSC-755913, KS-00001F76, NCGC00015245-10, NCGC00093753-01, NCGC00093753-02, NCGC00093753-03, NCGC00093753-04, NCGC00093753-05, NCGC00260989-01, AN-46182, AS-13371, BC204056, CC-25388, I014, LS-18505, SAM002548931, SAM002564198, Carbaminoyl, .beta.-methylcholine chloride, WLN: ZVOY1&1K1&1&1 &Q &G, AB2000570, carbamyl-B-methylcholinechloride*crystalline, EU-0100304, FT-0622944, 2-carbamoyloxypropyl(trimethyl)azanium chloride, C 5259, C08202, D01000, J10305, 2-aminocarbonyloxypropyl(trimethyl)azanium chloride, A832139, C-09023, I14-2242, SR-01000000282-2, SR-01000000282-4, SR-01000000282-7, 1-methyl-2-(trimethylamino)ethyl aminooate, chloride, [1-(trimethylaminiumyl)propan-2-yl] carbamate chloride, 2-[(aminocarbonyl)oxy]-N,N,N-trimethylpropan-1-aminium chloride, 2-[(AMINOCARBONYL) OXY]-N,N,N-TRIMETHYL-1-PROPANAMINIUMCHLORIDE, 21293-39-0, (non-labelled)Bethanechol-d6 Chloride

ID: 2653

chemical graph of compound 2653



InChIKey: XXWCODXIQWIHQN-UHFFFAOYSA-N
SMILES: C(CCN)CN.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9532
synonyms found at PubChem are:
1,4-Diaminobutane dihydrochloride, 333-93-7, Putrescine dihydrochloride, Tetramethylenediamine dihydrochloride, Putrescine hydrochloride, 1,4-Butanediamine dihydrochloride, UNII-X45SUR7RHY, 1,4-BUTANEDIAMINE, DIHYDROCHLORIDE, butane-1,4-diamine dihydrochloride, 1,4-Butanediamine, hydrochloride, 1,4-Diaminobutane, dihydrochloride, NSC 5861, EINECS 206-375-9, 1,4-Diaminobutane 2HCl, X45SUR7RHY, 1,4-Butanediamine, hydrochloride (1:2), AI3-18304, Tetramethylenediammonium dichloride, butane-1,4-diaminium dichloride, P-8000, Diaminobutane dihydrochloride, butane-1,4-diamine;dihydrochloride, SR-01000076079, 1,4-Diaminobutanedihydrochloride, Putrescindihydrochlorid, ACMC-1CMEU, 1,4-Diaminobutane DiHCl, AC1Q3AV7, SCHEMBL29458, KSC491O4B, SPECTRUM1503952, 1,4-Diaminobutanedihydrochlorid, AC1L1T94, Jsp006127, CHEMBL1528028, DTXSID5059824, CTK3J1740, BIP0733, MolPort-003-930-128, XXWCODXIQWIHQN-UHFFFAOYSA-N, ZX-AFC000366, KS-000009FZ, Tox21_500972, ACM333937, ANW-27625, CCG-39461, GP9873, MFCD00012526, AKOS015845890, AC-4426, API0008972, LP00972, RTR-032043, TRA0056188, NCGC00094272-01, NCGC00094272-02, NCGC00261657-01, AK-46742, AS-14367, BR-46742, K891, KB-10539, LS-45660, SC-20919, Putrescine dihydrochloride, >=98% (TLC), AB0014425, AB1000049, ST2414845, TR-032043, AM20090504, D0081, EU-0100972, FT-0082759, FT-0606835, M-6172, P 7505, SR-01000076079-1, SR-01000076079-4, 1,4-Diaminobutane dihydrochloride, purum, >=99.0% (AT), Putrescine dihydrochloride, Vetec(TM) reagent grade, >=98%, Putrescine dihydrochloride, powder, BioReagent, suitable for cell culture, 1,4-Butanediamine dihydrochloride; 1,4-Diaminobutane dihydrochloride; Putrescine dihydrochloride; Tetramethylenediamine dihydrochloride, 29142-66-3, Putrescine dihydrochloride, gamma-irradiated, lyophilized powder, BioXtra, suitable for cell culture, AC1LAP4K, tetramethylendiammonium-chlorid, CTK8D9986, 4-azaniumylbutylazanium dichloride, AKOS030569744, MolPort-028-751-638, AKOS025117319

ID: 2654

chemical graph of compound 2654



InChIKey: XXZSQOVSEBAPGS-UHFFFAOYSA-L
SMILES: C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 47320
synonyms found at PubChem are:
Atracurium besylate, Atracurium besilate, 64228-81-5, Tracrium, Atracurii besilas, Besilate d'atracurium, Besilato de atracurio, Atracurium (besylate), Tracrium Preservative Free, Atracurii besilas [INN-Latin], BW 33A, BW-33A, BW 33 A, Besilate d'atracurium [INN-French], EINECS 264-743-4, Atracurium Besylate Preservative Free, Besilato de atracurio [INN-Spanish], 33 A 74, CHEBI:2915, Tracrium (TN), Atracurium besilate (INN), Atracurium besilate [INN], 2-(2-Carboxyethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium benzenesulfonate, pentamethylene ester, benzenesulfonate; 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate, Pentamethylen bis(3-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-2-methyl-2-isochinolyl)propionat) bis(benzolsulfonat), 2,2'-((pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) benzenesulfonate, Isoquinolinium, 2,2'-(1,5-pentanediylbis(oxy(3-oxo-3,1-propanediyl)))bis(1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, dibenzenesulfonate, C53H72N2O12, hydro-1H-isoquinolin-2-ium-2-yl]propanoate, UNII-40AX66P76P, Atracurium besylate [USAN:BAN], Atracurium besylate [USAN:USP], NCGC00017127-01, C65H82N2O18S2, benzenesulfonate;5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-di, CAS-64228-81-5, LETROZOLEX, PubChem3018, TRACRIUM BESYLATE, AC1L2HUI, BW-33A BESYLATE, DSSTox_CID_2630, Atracurium besylate (USP), atracurium dibenzenesulfonate, DSSTox_RID_76665, DSSTox_GSID_22630, SCHEMBL41251, CHEMBL1200527, DTXSID6022630, HY-B0292A, MolPort-003-940-284, XXZSQOVSEBAPGS-UHFFFAOYSA-L, 40AX66P76P, HMS1568A11, HMS2095A11, HMS3651C21, HMS3712A11, Pharmakon1600-01505872, 64228-79-1 (Parent), benzenesulfonate; 5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1S,2S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propan, KS-00000L5H, Tox21_110790, CA0147, NSC760047, AKOS015895831, AB07163, AN-6664, Atracurium besylate, mixture of isomers, CCG-213566, CS-2306, DB00732, NC00429, NSC-760047, NCGC00262598-01, NCGC00262598-02, AN-15362, AS-14131, K027, AB1004899, LS-176358, TL8004537, A2566, FT-0659516, Atracurium besylate, >=98% (HPLC), powder, D00758, A834680, SR-01000781272, I06-1457, I14-0811, Q-101018, Q-200864, SR-01000781272-3, Atracurium besylate, European Pharmacopoeia (EP) Reference Standard, Atracurium besylate, United States Pharmacopeia (USP) Reference Standard, Atracurium for impurity F identification, European Pharmacopoeia (EP) Reference Standard, Atracurium for peak identification, European Pharmacopoeia (EP) Reference Standard, 2,2'-(3,3'-(pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium) benzenesulfonate, 2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] Dibenzenesulfonate, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-Isoquinolinium, dibenzenesulfonate (9CI); Atracurium besilate; Atracurium besylate; Atracurium dibesilate, 2,2'-[1,5-PENTANEDIYLBIS[OXY(3-OXO-3,1-PROPANEDIYL)]]BIS[1-[(3,4-DIMETHOXYPHENYL)METHYL]]-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-ISOQUINOLINIUM, BENZENESULFONATE (1:2), 2,2'-[1,5-PENTANEDIYLBIS[OXY(3-OXO-3,1-PROPANEDIYL)]]BIS[1-[3,4-DIMETHOXYPHENYL)METHYL]-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYLISO, 2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate, 2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-{[3,4-bis(methyloxy)phenyl]methyl}-2-methyl-6,7-bis(methyloxy)-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate, 2-(2-CARBOXYETHYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-VERATRYLISOQUINOLINIUM BENZENESULFONATE,PENTAMETHYLENE ESTER, benzenesulfonate; 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoic acid 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]-1-oxopropoxy]pentyl ester, ISOQUINOLINIUM,2,2'-[1,5-PENTANEDIYLBIS[OXY(3-OXO-3,1-PROPANEDIYL)]]BIS[1-(3,4-DIMETHOXYPHENYL)METHYL]-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-,DIBENZENESULFONATE, PENTAMETHYLENE BIS(3-(1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-1-(3,4-DIMETHOXYBENZYL)-2-METHYL-2-ISOCHINOLYL)PROPIONATE)BIS(BENZOLSULFONATE)

ID: 2655

chemical graph of compound 2655



InChIKey: XYHOHWPFEWJKOG-UHFFFAOYSA-N
SMILES: CCCCCCCCCC(=O)NC(CN1CCOCC1)C(C)C2=CC=CC=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 114736
synonyms found at PubChem are:
DAMPP, RV 538, 2-Decanoylamino-3-morpholino-1-phenylpropanol, threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, N-(2-Hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl)decanamide hydrochloride, Decanamide, N-(2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl)-, hydrochloride, RV-538, RV 538, (R-(R*,R*))-isomer, AC1L3FVK, AC1Q3E2I, C24H40N2O2.HCl, n-[1-(morpholin-4-yl)-3-phenylbutan-2-yl]decanamide hydrochloride(1:1), LS-177033, A813282, N-(1-morpholin-4-yl-3-phenyl-butan-2-yl)decanamide hydrochloride, N-(1-morpholin-4-yl-3-phenylbutan-2-yl)decanamide hydrochloride, N-[1-(4-morpholinyl)-3-phenylbutan-2-yl]decanamide hydrochloride

ID: 2656

chemical graph of compound 2656



InChIKey: XYNPYHXGMWJBLV-VXPJTDKGSA-N
SMILES: C[C@H]1CC[C@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)NC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 65576
synonyms found at PubChem are:
Tomatidine, 77-59-8, Tomatidin, UNII-2B73S48786, (3beta,5alpha,22beta,25S)-Spirosolan-3-ol, EINECS 201-040-3, NSC 27592, NSC 226903, CHEBI:9629, 5alpha-Tomatidan-3beta-ol, (22S,25S)-5alpha-spirosolan-3beta-ol, 2B73S48786, Spirosolan-3-ol, (3beta,5alpha,22beta,25S)-, SMR001233234, 5alpha-Tomatidan-3beta-ol (8CI), SR-05000002324, (3beta,5alpha,25S)-spirosolan-3-ol, Prestwick_473, Prestwick3_000573, BSPBio_000386, MLS002153880, MLS002222215, SCHEMBL335093, AC1L23J5, BPBio1_000426, CHEMBL2165711, DTXSID0037102, HMS2096D08, HY-N2149, ZINC8143640, 8282AH, CCG-208279, CS-5821, SMP1_000126, NCGC00179576-01, LS-184563, C10826, SR-05000002324-3

ID: 2657

chemical graph of compound 2657



InChIKey: XYPGDMUIGARFDK-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1C2=NOC(=C2)CO

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 10822101
synonyms found at PubChem are:
345967-78-4, (3-(2-Methoxyphenyl)isoxazol-5-yl)methanol, [3-(2-Methoxy-phenyl)-isoxazol-5-yl]-methanol, [3-(2-methoxyphenyl)-1,2-oxazol-5-yl]methanol, [3-(2-methoxyphenyl)isoxazol-5-yl]methanol, CHEMBL86154, SCHEMBL16915404, CTK8I3331, 9323AH, ZINC26572543, AKOS013482828, AB27277, ACM345967784, AJ-82611, AK153735, KB-07366, AX8028444, DB-069038, FT-0695428, 3-(2-methoxyphenyl)-5-hydroxymethylisoxazole, 3-(2-Methoxyphenyl)-5-(hydroxymethyl)isoxazole, (3-(2-Methoxyphenyl)isoxazol-5-yl)methanol, AldrichCPR

ID: 2658

chemical graph of compound 2658



InChIKey: XYPPDQHBNJURHU-IPOQXWOTSA-N
SMILES: C[C@@H]1CC[C@@H]2[C@@]([C@@]13CC[C@](O3)(CCO)CO)(CC[C@@H]([C@@]2(C)CO)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 7061097
synonyms found at PubChem are:
Lagochilin, Lagochiline, 23554-81-6, AC1OEQ0K, CHEMBL2165226, ZINC3881717, 131898-43-6, (1R,2S,4aS,5R,5'S,6R,8aS)-5'-(2-hydroxyethyl)-1,5'-bis(hydroxymethyl)-1,4a,6-trimethylspiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxolane]-2-ol

ID: 2659

chemical graph of compound 2659



InChIKey: XZMHJYWMCRQSSI-UHFFFAOYSA-N
SMILES: CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CSC(=N3)NC4=CC=CC(=C4)C(=O)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "N Pedemonte" "GL Lukacs" "LJ Galietta" "O Zegarra-Moran" "AS Verkman" "K Du"


CID is 2230879
synonyms found at PubChem are:
N-[2-(3-Acetyl-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide, N-{2-[(3-acetylphenyl)amino]-4'-methyl-4,5'-bi-1,3-thiazol-2'-yl}benzamide, Compound 4c, BAS 01247286, AC1M33KG, SCHEMBL837699, MolPort-000-690-616, ZINC2878845, STK027021, AKOS000565149, MCULE-5215377073, EU-0009712, J3.654.387F, SR-01000477244, SR-01000477244-1, N-(3-Acetylphenyl)-N'-benzoyl-4'-methyl-4,5'-bithiazole-2,2'-diamine, N-[5-[2-(3-acetylanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide

ID: 2660

chemical graph of compound 2660



InChIKey: XZNUGFQTQHRASN-XQENGBIVSA-N
SMILES: CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3081545
synonyms found at PubChem are:
apramycin, Nebramycin II, 37321-09-8, Nebramycin factor 2, Apramycinum, Apramicina, Apramycine, UNII-388K3TR36Z, Ambylan, Apralan, CHEBI:2790, 388K3TR36Z, 4-O-((8R)-2-Amino-8-O-(4-amino-4-deoxy-alpha-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine, 4-O-(3alpha-Amino-6alpha-((4-amino-4-deoxy-alpha-D-glucopyranosyl)oxy)-2,3,4,5abeta,6,7,8,8aalpha-octahydro-8beta-hydroxy-7beta-(methylamino)pyrano(3,2-b)pyran-2alpha-yl)-2-deoxy-D-streptamine, Apramycine [INN-French], Apramycinum [INN-Latin], Apramicina [INN-Spanish], EINECS 253-460-1, EL 857, (2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)octahydropyrano[3,2-b]pyran-2-yl 4-amino-4-deoxy-alpha-D-glucopyranoside, AM2, EL-857/820, Apramycin [USAN:INN:BAN], EL-857, NCGC00016836-01, CAS-37321-09-8, Apramycin (USAN/INN), AC1MIX4B, DSSTox_CID_25465, DSSTox_RID_80896, DSSTox_GSID_45465, SCHEMBL18388, CHEMBL1230961, DTXSID5045465, MolPort-003-983-409, HMS2090I15, D-Streptamine, 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-alpha-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-, ZINC8214486, Tox21_110639, 65710-07-8 (unspecified sulfate), AKOS032944905, API0006565, CS-3070, DB04626, CC-24164, HY-17558, O211, C01555, D02322, AB01275497-01, Apramycin, Antibiotic for Culture Media Use Only, C-23144, W-106548, UNII-NQJ13I4Z9U component XZNUGFQTQHRASN-XQENGBIVSA-N, (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol, (2R,3R,4S,5S,6S)-5-amino-2-((2R,3S,4R,4aR,6S,7R)-7-amino-6-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyloxy)-4-hydroxy-3-(methylamino)octahydropyrano[3,2-b]pyran-2-yloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol, D-Streptamine, O-4-amino-4-deoxy-alpha-D-glucopyranosyl-(1.fwdarw.8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1.fwdarw.4)-2-deoxy-, NEBRAMYCIN II, 4-O-(3ALPHA-AMINO-6ALPHA-((4-AMINO-4-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY)-2,3,4,5ABETA,6,7,8,8AALPHA-OCTAHYDRO-8BETA-HYDROXY-7BETA-(METHYLAMINO)PYRANO(3,2-B)PYRAN-2ALPHA-YL)-2-DEOXY-D-STREPTAMINE

ID: 2661

chemical graph of compound 2661



InChIKey: XZTUSOXSLKTKJQ-CESUGQOBSA-N
SMILES: C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4369270
synonyms found at PubChem are:
Digitoxigenin, 143-62-4, Thevetigenin, Echujetin, Digitoxigenine, Cerberigenin, Evonogenin, UNII-S63WOD4VOL, MLS002153810, S63WOD4VOL, NSC 407806, 3b,14-Dihydroxy-5b-card-20(22)-enolide, CHEBI:42219, XZTUSOXSLKTKJQ-CESUGQOBSA-N, 3beta,14-Dihydroxy-5beta-card-20(22)-enolide, SMR001233182, 3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 3-beta,14beta-dihydroxy-5-beta-card-20(22)-enolide, 3.beta.,14-Dihydroxy-5.beta.-card-20(22)-enolide, EINECS 205-603-4, BRN 0095448, 4-(3,14-DIHYDROXY-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-17-YL)-5H-FURAN-2-ONE, DTX, 3-beta,14-Dioxy-digen-(20:22)-olid [German], 3-beta,14-Dihydroxy-5-beta-card-20(22)-enolide, 3-beta,14-Dioxy-carden-(20:22)-olid [German], Cardogenen-(20:22)-diol-(3-beta,14) [German], MLS002701726, delta20:22-3,14,21-Trihydroxynorcholenic acid lactone, 3-beta,14-Dihydroxy-5-beta,14-beta-card-20(22)-enolide, Card-20(22)-enolide, 3,14-dihydroxy-, (3-beta,5-beta)-, delta-sup(20:22)-3,14,21-Trihydroxynorcholenic acid lactone, delta-sup(20:22)-3,14,21-Trihydroxynorcholenicacid lactone, NSC407806, 1lnm, Prestwick_169, 3-beta,14-Dioxy-carden-(20:22)-olid, 3-beta,14-Dioxy-digen-(20:22)-olid, Cardogenen-(20:22)-diol-(3-beta,14), AC1N9ZUQ, Prestwick0_000436, Prestwick1_000436, Prestwick2_000436, Prestwick3_000436, D08ZNS, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,14-DIHYDROXY-, CHEMBL1453, SCHEMBL61224, BSPBio_000452, 5-18-03-00348 (Beilstein Handbook Reference), SPBio_002391, BPBio1_000498, BDBM66977, cid_4369270, DTXSID80162276, MolPort-002-513-646, HMS1569G14, HMS2096G14, HMS2231J22, HMS3713G14, KS-000016KV, ZINC3875959, 7051AA, LMST01120001, MFCD00003687, AKOS015915862, ACN-030380, API0002356, CCG-220436, DB04177, NSC-407806, NCGC00179555-01, 5beta,20(22)-Cardenolide-3beta,14-diol, ST2406798, 3-.beta.,14-Dioxy-digen-(20:22)-olid, D0541, Cardogenen-(20:22)-diol-(3-.beta.,14), 3beta,14-Dihydroxy-5beta,20(22)-cardenolide, 5.beta.-Card-20(22)-enolide,14-dihydroxy-, 3-BETA, 14-BETA-CARD-20(22)-ENOLIDE, SR-01000841188, SR-01000841188-2, 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone, BRD-K18518344-001-03-5, I14-53594, .delta.20:22-3,21-Trihydroxynorcholenic acid lactone, 5.beta.-Card-20(22)-enolide, 3.beta.,14-dihydroxy, 5.beta.-Card-20(22)-enolide, 3.beta.,14-dihydroxy-, WLN: L E5 B666TJ A1 E1 F- DT5OV CUTJ IQ OQ, .delta.20:22-3,14,21-Trihydroxynorcholenic acid lactone, 5beta-Card-20(22)-enolide, 3beta,14-dihydroxy- (8CI), .delta.-sup(20:22)-3,21-Trihydroxynorcholenic acid lactone, 3,14,21-EyoC>>u-20(22)-E yen(1/4)xmicro I(c)EaAUo yen, 3,14-Dihydroxycard-20(22)-enolide, (3.beta.,5.beta.)- #, Card-20(22)-enolide,14-dihydroxy-, (3.beta.,5.beta.)-, .DELTA.-sup(20:22)-3,14,21-Trihydroxynorcholenicacid lactone, Card-20(22)-enolide, 3,14-dihydroxy-, (3.beta.,5.beta.)-, Card-20(22)-enolide, 3,14-dihydroxy-, (3beta,5beta)- (9CI), 3|A,14- paragraph signthornoC>>u-5|A,20(22)- inverted question mark I(c)AUo yen, 5|A,20(22)- inverted question mark I(c)AUo yen-3|A,14- paragraph signthorn (1/4), 3-[(3S,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,14-bis(oxidanyl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 4-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one

ID: 2662

chemical graph of compound 2662



InChIKey: XZWMZFQOHTWGQE-UHFFFAOYSA-N
SMILES: CC1=NNC(=O)NC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 70269
synonyms found at PubChem are:
6-Azathymine, 932-53-6, 6-Methyl-1,2,4-triazine-3,5(2H,4H)-dione, 5-Methyl-6-azauracil, Azathymine, USAF CB-28, 1,2,4-Triazine-3,5(2H,4H)-dione, 6-methyl-, 6-Methyl-1,2,4-triazine-3,5-dione, 6-methyl-2H-1,2,4-triazine-3,5-dione, UNII-ZWX58T58ZA, Azathymine, 6, NSC 3426, 6-Methyl-as-triazine-3,5-(2H,4H)-dione, NSC 38620, 6-Methyl-1,2,4-triazine-3,5-diol, CCRIS 3440, 3,5-Dihydroxy-6-methyl-1,2,4-triazine, 6-Methyl-as-triazine-3,5-diol, as-Triazine-3,5(2H,4H)-dione, 6-methyl-, EINECS 213-253-9, ZWX58T58ZA, AI3-50849, XZWMZFQOHTWGQE-UHFFFAOYSA-N, A-9600, WLN: T6NMVMVJ F1, AO-089/25085002, 6-Methyl-as-triazine-3,4H)-dione, 6-Methyl-1,4-triazine-3,5-dione, as-Triazine-3,4H)-dione, 6-methyl-, 6-methyl-2H,4H-1,2,4-triazine-3,5-dione, 1,4-Triazine-3,5(2H,4H)-dione, 6-methyl-, Prestwick_662, ACMC-209rkt, AC1L2DPT, AC1Q6CIM, Prestwick0_000483, Prestwick1_000483, Prestwick2_000483, Prestwick3_000483, BSPBio_000345, SCHEMBL814784, SPBio_002266, BPBio1_000381, TRI001, CHEMBL1741493, SCHEMBL10976253, CTK5H2221, XZWMZFQOHTWGQE-UHFFFAOYSA-, DTXSID70239325, NSC3426, CHEBI:102328, MolPort-000-367-665, MolPort-000-669-770, MolPort-008-011-389, HMS1569B07, HMS2096B07, ALBB-012970, As-triazine-3,5-diol, 6-methyl-, KS-000013YV, NSC-3426, NSC38620, ZX-AN011758, ANW-40011, BBL003529, FCH925677, MFCD00006457, NSC-38620, SBB017571, STK895085, STL216013, ZINC11666592, AKOS002339212, AKOS002350513, AKOS002860206, AKOS015866154, MCULE-1502977032, NUC0000658, VZ35694, NCGC00016550-01, NCGC00016550-02, AK162086, CAS-932-53-6, K697, SC-46360, 6-Aza-2,4-dihydorxy-5-methyl-pyrimidine, 6-Methyl-as-triazine-3,5(2H,4H)-dione, 6-Aza-2,4-dihydroxy-5-methyl- pyrimidine, AB0014337, AX8023162, LS-155397, 6-methyl-2H-[1,2,4]triazine-3,5-dione, A0556, FT-0620951, R1146, ST45022008, 5-hydroxy-6-methyl-1,2,4-triazin-3(2H)-one, 1,2,4-Triazine-3,5(2H,4H)-dione,6-methyl-, 932A536, A844488, I14-27753, F3098-5172, 1,2,4-Triazine-3,5(2H,4H)-dione, 6-methyl- (9CI), InChI=1/C4H5N3O2/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9), 16075-91-5

ID: 2663

chemical graph of compound 2663



InChIKey: XZZXIYZZBJDEEP-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8228
synonyms found at PubChem are:
Imipramine hydrochloride, 113-52-0, Imipramine Hcl, Tofranil, Chimoreptin, Chrytemin, Deprinol, Feinalmin, Imilanyle, Persamine, Pertofram, Presamine, Pryleugan, Teperine, Tofranile, Iprogen, IMP hydrochloride, IA-Pram, Imizin, Psicopramine, Thymopramin, Dynazina, Efuranol, Fujisawa, Imipramini, Odeoxil, Tipramine, Venefon, Imidol, Vionyl, Co cap imipramine 25, Antideprin hydrochloride, Imipramine monohydrochloride, Imipramini hydrochloridum, SK-Pramine hydrochloride, UNII-BKE5Q1J60U, Imipramine, Hydrochloride, EINECS 204-030-7, Imipramine (hydrochloride), G 22355, NSC 114900, N-(3-Dimethylaminopropyl)iminodibenzyl hydrochloride, BKE5Q1J60U, C19H24N2.HCl, MLS000028430, CHEBI:5882, N-(gamma-Dimethylaminopropyl)iminodibenzyl hydrochloride, CPD000058388, SMR000058388, N-(gamma-Dimetilaminopropil)-iminodibenzile cloridrato [Italian], Tofranil (TN), 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz(b,f)azepine hydrochloride, 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride, 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-, hydrochloride, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride, Q-200878, Imipram, Melipramine HCl, imipramine hydrochloride,berkomine,deprinol,dyna-zina,imiprin,iramil, 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride, 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, monohydrochloride, 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride, (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride, Melipramine hydrochloride, SR-01000003064, CAS-113-52-0, ST50985122, ImipramineHCl, Imipramine hydrochloride [JAN], cocapimipramine25, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1), 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1), SK-Pramine HCl, Prestwick_277, Imipramine hydrochloride [USP:JAN], antideprinhydrochloride, Nebumetone Impurity D, (3-(10H,11H-dibenzo[b,f]azepin-5-yl)propyl)dimethylamine, chloride, Opera_ID_319, Imipramine(hydrochloride), AC1L1QJV, SureCN41766, AC1Q3BL7, CHEMBL1692, DSSTox_CID_20738, DSSTox_RID_79581, DSSTox_GSID_40738, G 22150, REGID_for_CID_8228, SCHEMBL41765, MLS001146891, MLS002222195, 50-49-7 (Parent), SPECTRUM1500348, N-(gamma-Dimetilaminopropil)-iminodibenzile cloridrato, DTXSID7040738, CTK8E8407, MolPort-003-666-208, XZZXIYZZBJDEEP-UHFFFAOYSA-N, HMS1568O05, HMS1920F17, Pharmakon1600-01500348, HY-B1490, KS-00001FC4, KS-00002WV4, Tox21_301417, Tox21_500702, BG0219, CCG-40208, MFCD00012669, NSC114900, NSC757074, SBB057673, Imipramine hydrochloride (JP17/USP), AKOS015895330, AC-7587, AN-8868, API0002985, CS-6180, KS-1072, LP00702, MCULE-5997199711, NC00570, NSC-114900, NSC-757074, NCGC00024253-05, NCGC00094054-01, NCGC00094054-02, NCGC00094054-03, NCGC00094054-04, NCGC00094054-05, NCGC00255651-01, NCGC00261387-01, AK175066, BC210152, CC-29494, Imipramine hydrochloride, >=99% (TLC), LS-60471, M569, SAM002564216, AB1009320, TR-002613, EU-0100702, FT-0631652, I0971, C07982, D00815, I 7379, 113I520, Imipramine hydrochloride, BioXtra, >=99% (TLC), Imipramine hydrochloride, Sigma Reference Standard, I06-0739, J-002975, SR-01000003064-2, SR-01000003064-7, 5-(3-dimethylaminopropyl)-10,f)azepine hydrochloride, WLN: T C676 BN & T & J B3N1 & 1 & GH, Z1551429721, N-(.gamma.-Dimethylaminopropyl)iminodibenzyl hydrochloride, 5H-Dibenz[b, 10,11-dihydro-N,N-dimethyl-, monohydrochloride, Imipramine Hydrochloride 1.0 mg/ml in Methanol (as free base), 10,11-Dihydro-N,N-dimethyl- dibenz[b,f]azepine-5- propanamine, 10,11-dihydro-n,n-dimithyl-5,h-dibenz[b,f]azepine-5-propanamine, 10,11-Dihydro-N,N-dimethyl-dibenz[b,f]azepine-5-propanamine hydrochloride, 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride, 5H-Dibenz[b, 10,11-dihydro-5-[3-(dimethylamino)propyl]-, hydrochloride, Imipramine hydrochloride, European Pharmacopoeia (EP) Reference Standard, 10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine hydrochloride, 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, 10,11-Dihydro-N,N-dimethyl-5H-dibenzo[b,f]azepine-5-propanamine Hydrochloride, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine hydrochloride, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine hydrochloride, 5-(3-Dimethylaminopropyl)-10,11-dihydro-5h-dibenz-[b,f]-azepine, hydrochloride, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine Hydrochloride, 5H-Dibenz[b, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride, 5h-dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-,monohydrochloride, Imipramine for system suitability, European Pharmacopoeia (EP) Reference Standard, Imipramine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Imipramine hydrochloride, United States Pharmacopeia (USP) Reference Standard, (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride, 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride; 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride, AC1LCW6L, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine; hydron; chloride, 5-3-(Dimethylamino)propyl-10,11-dihydro-5H-dibenz[ b, f]-azepine monohydrochloride, AKOS024356992, 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-aminium chloride

ID: 2664

chemical graph of compound 2664



InChIKey: YAPQBXQYLJRXSA-UHFFFAOYSA-N
SMILES: CN1C=NC2=C1C(=O)NC(=O)N2C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5429
synonyms found at PubChem are:
theobromine, 83-67-0, 3,7-Dimethylxanthine, Diurobromine, Teobromin, Theosalvose, Theostene, Santheose, Thesodate, Thesal, Theobromin, 3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione, 3,7-dimethylpurine-2,6-dione, Xanthine, 3,7-dimethyl-, 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-, SC 15090, 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione, Theobromine (natural), 2,6-Dihydroxy-3,7-dimethylpurine, UNII-OBD445WZ5P, NSC 5039, 7-Dimethylxanthine, 2,6-Dihydroxy-3,7-dimethyl-purine, BRN 0016464, FEMA No. 3591, CCRIS 2350, HSDB 7332, 3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, EINECS 201-494-2, CHEMBL1114, OBD445WZ5P, CHEBI:28946, NSC5039, YAPQBXQYLJRXSA-UHFFFAOYSA-N, CAS-83-67-0, NCGC00016023-11, DSSTox_CID_6132, 3,7-Dimethyl-1H-purine-2,6(3H,7H)-dione, 3,7-dimethyl-1,3,7-trihydropurine-2,6-dione, DSSTox_RID_78030, DSSTox_GSID_26132, Theobromine [BAN], SR-01000000069, Theobromine [INN:BAN:NF], Xantheose, paraxanthine;, Theobromine;, Cocoa Theobromine, Prestwick_1054, Theobromine(20%), 3,7-dimethylxanthin, 3,7-dimethyl xanthine, Spectrum_000053, 3,7-Dimethyl-xanthine, Prestwick0_000874, Prestwick1_000874, Prestwick2_000874, Prestwick3_000874, Spectrum2_000985, Spectrum3_000279, Spectrum4_000403, Spectrum5_001387, Lopac-T-4500, ACMC-209pt0, D0I0DS, AC1L1KC8, SCHEMBL3184, Theobromine, >=98.0%, Lopac0_001187, BSPBio_000947, BSPBio_001758, KBioGR_000666, KBioSS_000433, 5-26-13-00553 (Beilstein Handbook Reference), KSC491G3F, MLS000028407, ARONIS24350, DivK1c_000611, SPECTRUM1500649, SPBio_001049, SPBio_002868, AC1Q3Z26, BPBio1_001043, ZINC2151, Theobromine, analytical standard, DTXSID9026132, CTK3J1332, HMS501O13, KBio1_000611, KBio2_000433, KBio2_003001, KBio2_005569, KBio3_001258, YAPQBXQYLJRXSA-UHFFFAOYSA-, MolPort-000-514-708, NINDS_000611, HMS1570P09, HMS1921O13, HMS2092G04, HMS2097P09, HMS3263N15, HMS3714P09, Pharmakon1600-01500649, EBD26471, HY-N0138, NSC-5039, Theobromine 0.1 mg/ml in Methanol, Theobromine (3,7-Dimethylxanthine), Theobromine, >=98.0% (HPLC), Tox21_110284, Tox21_300016, Tox21_501187, ANW-37714, BBL034679, BDBM50014260, CCG-40078, MFCD00022830, NSC757407, PDSP1_001017, PDSP2_001001, s2368, SBB012378, STL419465, AKOS000121558, Tox21_110284_1, 5-26-13-00553 (Beilstein), CS-7972, DB01412, LP01187, LS-1828, LS00156, MCULE-3914097400, NE10843, NSC-757407, SDCCGMLS-0002875.P003, IDI1_000611, NCGC00016023-01, NCGC00016023-02, NCGC00016023-03, NCGC00016023-04, NCGC00016023-05, NCGC00016023-06, NCGC00016023-07, NCGC00016023-08, NCGC00016023-09, NCGC00016023-10, NCGC00016023-12, NCGC00016023-13, NCGC00016023-14, NCGC00016023-15, NCGC00016023-17, NCGC00016023-18, NCGC00024123-03, NCGC00024123-04, NCGC00024123-05, NCGC00024123-06, NCGC00024123-07, NCGC00024123-08, NCGC00179030-01, NCGC00179030-02, NCGC00253943-01, NCGC00261872-01, WLN: T56 BN DN FNVMVJ B1 F1, AC-11381, AN-42268, AS-13904, BC003475, Q815, SC-06911, SC-90343, SMR000058357, ST069337, ZB000492, SBI-0051154.P003, 1H-Purine-2, 3,7-dihydro-3,7-dimethyl-, AB00052141, EU-0101187, FT-0660435, N1573, 7129-EP2269610A2, 7129-EP2277848A1, 7129-EP2277867A2, 7129-EP2280003A2, 7129-EP2284160A1, 7129-EP2289510A1, 7129-EP2295409A1, 7129-EP2298772A1, 7129-EP2301937A1, 7129-EP2305677A1, 7129-EP2305682A1, 7129-EP2308839A1, 7129-EP2308840A1, 7129-EP2308879A1, 7129-EP2311842A2, 7129-EP2314590A1, 7129-EP2314593A1, 7129-EP2316457A1, 7129-EP2316458A1, 7129-EP2316825A1, 7129-EP2316826A1, 7129-EP2316827A1, 7129-EP2316828A1, C07480, T 4500, 59621-EP2308852A1, AB00052141_12, 3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione #, I14-9714, Q-100848, SR-01000000069-2, SR-01000000069-4, SR-01000000069-7, SR-01000000069-8, SR-01000000069-9, 3,7-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE, BRD-K34888156-001-08-8, CEC63CCA-3B4B-4F4F-92C1-1789DF3C880A, SR-01000000069-10, Z56347209, 1H-purine-2,6-dione,3,7-dihydro-3,7- dimethyl- (9CI), Theobromine, European Pharmacopoeia (EP) Reference Standard, Theobromine, Pharmaceutical Secondary Standard; Certified Reference Material, 37T, InChI=1/C7H8N4O2/c1-10-3-8-5-4(10)6(12)9-7(13)11(5)2/h3H,1-2H3,(H,9,12,13)

ID: 2665

chemical graph of compound 2665



InChIKey: YASAKCUCGLMORW-UHFFFAOYSA-N
SMILES: CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 77999
synonyms found at PubChem are:
rosiglitazone, 122320-73-4, Avandia, 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione, Brl-49653, Rosiglizole, Brl 49653, rosiglitazone (Avandia), BRL49653, rosiglitazona, rosiglitazonum, Avandaryl, Rosiglitazone [INN:BAN], Avandamet, TDZ 01, CHEBI:50122, Rosigilitazone, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 5-((4-(2-Methyl-2-(pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione-2-butenedioate, C18H19N3O3S, YASAKCUCGLMORW-UHFFFAOYSA-N, NCGC00095124-01, 5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione, 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-, DSSTox_CID_17131, DSSTox_RID_79303, DSSTox_GSID_37131, Q-201681, 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, 2,4-thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione, CAS-122320-73-4, SR-01000763023, Rosiglitazon, Rosi, HSDB 7555, Rosiglitazone base, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, 5-[4-[2-[N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, Rosigliazone maleate, Gaudil (TN), Rosiglitazone (INN), Spectrum_001703, 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione, 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Spectrum2_001241, Spectrum3_000997, Spectrum4_001125, Spectrum5_001464, Avandia;BRL-49653, AC1L2U9N, SCHEMBL5169, BSPBio_002693, KBioGR_001609, KBioSS_002183, KSC914G9L, SPECTRUM1504263, SPBio_001142, GTPL1056, DTXSID7037131, SCHEMBL14383595, CTK8B4395, KBio2_002183, KBio2_004751, KBio2_007319, KBio3_001913, KS-00000IPU, MolPort-002-508-212, Rosiglitazone, >=98% (HPLC), HMS1922J11, HMS2094O13, HMS3649G08, HMS3656K16, Pharmakon1600-01504263, ACT04332, BCP03047, Tox21_111434, ANW-44906, BBL029079, BDBM50030474, BG0432, CCG-39102, GP6434, MFCD00871760, NSC758698, STL350047, AKOS015894872, Tox21_111434_1, AC-3459, API0006964, BCP9000017, CS-1088, DB00412, MCULE-8293284864, MP-0331, NSC-758698, RTC-064102, VA11695, 2,4-Thiazolidinedione, 5-004-02-((((methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-, NCGC00095124-02, NCGC00095124-03, NCGC00095124-04, NCGC00095124-05, NCGC00095124-06, NCGC00095124-08, 4CA-1110, AK-72839, AN-12970, BR-72839, CC-34292, HY-17386, SC-19017, BCP0726000232, AB0011992, AB2000652, AX8017813, LS-151340, FT-0602578, R0106, S2556, ST24029274, 20R734, 6P-065, D08491, J10213, S00306, AB00698473-15, AB00698473-17, AB00698473-18, AB00698473-19, AB00698473_20, AB00698473_21, AB00698473_22, AB00698473_23, C-20817, I06-0141, SR-01000763023-5, SR-01000763023-6, BRD-A97437073-001-02-3, BRD-A97437073-001-03-1, BRD-A97437073-001-04-9, SR-01000763023-12, (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion, 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4dione, 5-[4-[2-[Methyl(2-pyridyl)amino]ethoxy]benzyl]thiazolidine-2,4-dione, IDMB (1uM BRL49653, 1uM Dexamethasone, 0.5uM IBMX, 10ug/mL Insulin), (+/-)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione, 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]- (9CI), 5-[[4-[2-(methyl-(2-pyridyl)amino)ethoxy]phenyl]methyl] thiazolidine-2,4-dione, 5-[[4-[2-(methyl-2-pyridinylamino) ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 5-[[4-[2-(methyl-pyridin-2-ylamino)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, 5-[[4-[2-[methyl(2-pyridyl)amino]ethoxy]phenyl]methyl]thiazolidine-2,4-dione, 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl] thiazolidine-2,4-dione, 5-[4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]phenyl methyl]thiazolidine-2,4-dione

ID: 2666

chemical graph of compound 2666



InChIKey: YAWWQIFONIPBKT-FQEVSTJZSA-N
SMILES: CCCC[C@]1(CC2=CC(=C(C(=C2C1=O)Cl)Cl)OCC(=O)O)C3CCCC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10386195
synonyms found at PubChem are:
R(+)-Butylindazone, R-(+)-DIOA, 81166-47-4, R(+)-DIOA, R-(+)-[(2-n-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid, Lopac0_000457, MLS002153191, C20H24Cl2O4, CHEMBL1256719, DTXSID40439113, HMS2235L14, HMS3261K16, HMS3374K10, ZINC3874840, Tox21_500457, MFCD00069261, CCG-204549, LP00457, NCGC00093872-01, NCGC00093872-02, NCGC00093872-03, NCGC00261142-01, SMR000326932, D-129, EU-0100457, FT-0773868, X6846, R-(+)-DIOA, >=98% (HPLC), solid, C-54148, SR-01000075313, SR-01000075313-1, (S)-2-(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yloxy)acetic acid

ID: 2667

chemical graph of compound 2667



InChIKey: YAZSBRQTAHVVGE-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)N)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 72894
synonyms found at PubChem are:
2-Aminobenzenesulfonamide, 3306-62-5, Orthanilamide, o-Aminobenzenesulfonamide, o-Sulfanilamide, Benzenesulfonamide, 2-amino-, 2-Amino-benzenesulfonamide, Benzenesulfonamide, o-amino-, 2-aminobenzene-1-sulfonamide, o-Aminobenzenesulphonamide, EINECS 221-988-1, NSC 36945, BRN 0512329, CHEMBL6705, YAZSBRQTAHVVGE-UHFFFAOYSA-N, Benzenesulfonamide, 2-amino- (9CI), o-sulfamoylaniline, orthanilamide 17, 2-Sulphamoylaniline, aminobenzolsulfonamid, aminobenzene sulfonamide, 2-amino-benzensulfonamide, AC1L2IWK, o -aminobenzenesulfonamide, Prestwick0_000913, Prestwick1_000913, Prestwick2_000913, Prestwick3_000913, 2-Aminobenzenesulphonamide, 2-amino benzenesulfonamide, 2-Aminobenzene sulfonamide, 2-Aminobenzene-sulfonamide, ACMC-209hy7, D0OI1H, AC1Q50VN, BSPBio_000786, 4-14-00-02638 (Beilstein Handbook Reference), MLS002154059, SCHEMBL183126, SPBio_002975, BPBio1_000866, Jsp006085, 2-Aminobenzenesulfonamide, 98%, BDBM10855, CHEBI:94579, CTK3J3143, DTXSID00186717, MolPort-001-765-874, HMS1570H08, HMS2097H08, HMS2230O21, HMS3373I09, HMS3714H08, ZINC163348, ALBB-023260, HY-B2147, NSC36945, ANW-27533, aromatic/heteroaromatic sulfonamide 1, MFCD00007932, NSC-36945, SBB071583, 2-Aminobenzenesulfonamide, 98% 5g, AKOS000137240, CCG-214466, CS-7986, MCULE-3556055595, PS-4507, KS-0000105R, NCGC00016625-01, NCGC00016625-02, AC-16099, AJ-16020, BP-10578, KB-84777, LS-31209, R514, SC-80430, SMR001233376, ZB007972, CAS-3306-62-5, AB0018199, AB1002996, DB-020509, RT-001283, ST2404149, AB00513960, FT-0082180, FT-0602047, ST45026540, EN300-50902, M-2771, 306A625, SR-01000841823, SR-01000841823-2, W-106790, BRD-K32681104-001-03-3

ID: 2668

chemical graph of compound 2668



InChIKey: YBHMPNRDOVPQIN-VSOYFRJCSA-N
SMILES: CCCCC[C@@H](/C=C/C1=C(C(=O)CC1)CCCCCCC(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5280388
synonyms found at PubChem are:
prostaglandin B1, PGB1, 13345-51-2, Prostaglandin Bx, UNII-1TYI1PJ64T, 1TYI1PJ64T, MLS000069509, CHEMBL1561148, CHEBI:27624, (13E,15S)-15-hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid, 9-oxo-15S-hydroxy-8(12),13E-prostadienoic acid, 39306-29-1, SMR000058636, Prosta-8(12),13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-, 15(S)-hydroxy-9-oxo-8(12),13-trans-prostadienoic acid, PGBx, PGB1 (Prostaglandin B1), SR-01000000044, Prostaglandin-B1, (13E,15S)-15-hydroxy-9-oxoprosta-8(12),13-dien-1-oate, AC1NQWZ8, Opera_ID_1128, Prostaglandin B1 synthetic, BSPBio_001482, Prostaglandin Bx, sodium salt, BML1-F03, SCHEMBL9576915, SCHEMBL9576919, Prosta-8(12),13-dien-1-oicacid, 15-hydroxy-9-oxo-, (13E,15S)-, DTXSID70192547, MolPort-003-939-178, YBHMPNRDOVPQIN-VSOYFRJCSA-N, HMS1361K04, HMS1791K04, HMS1989K04, HMS2233A12, HMS3402K04, HMS3648K15, ZINC3874778, Prostaglandin B1, synthetic, powder, 2002AH, BDBM50390997, LMFA03010131, MFCD00036679, CCG-208254, IDI1_033952, NCGC00024019-03, NCGC00024019-04, NCGC00024019-05, 9-oxo-15S-hydroxy-8(12),13E-prostadienoate, C00959, J-006385, SR-01000000044-4, SR-01000000044-5, SR-01000000044-6, (S,E)-7-(2-(3-hydroxyoct-1-enyl)-5-oxocyclopent-1-enyl)heptanoic acid, 7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopenten-1-yl]heptanoic acid, 7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopenten-1-yl]heptanoic acid, Prostaglandin B1, United States Pharmacopeia (USP) Reference Standard

ID: 2669

chemical graph of compound 2669



InChIKey: YBJHBAHKTGYVGT-ZKWXMUAHSA-N
SMILES: C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 171548
synonyms found at PubChem are:
biotin, d-biotin, vitamin H, 58-85-5, coenzyme R, Vitamin B7, Bios II, Factor S, Bioepiderm, D(+)-Biotin, Biodermatin, Medebiotin, Biotinum, Biotine, Meribin, Factor S (vitamin), Injacom H, Lutavit H2, Biotina, (+)-Biotin, beta-Biotin, Vitamin Bw, 3H-Biotin, NSC 63865, CCRIS 3932, HSDB 346, Biotine [INN-French], Biotinum [INN-Latin], Biotina [INN-Spanish], Biotin Forte, 1swk, 1swn, 1swr, Rovimix H2, Rovimix H 2, D-Biotin Factor S, UNII-6SO6U10H04, cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid, cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid, D-(+)-Biotin, AI3-51198, EINECS 200-399-3, cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid, (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid, 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4beta,6aalpha))-, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid, 2'-Keto-3,4-imidazolido-2-tetrahydrothiophene-N-valeric acid, CHEBI:15956, 6SO6U10H04, (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-valeric acid, 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid, Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid, (3aS-(3aalpha,4beta,6aalpha))-, DSSTox_CID_2679, (3aS-(3aalpha,4b,6aalpha))-Hexahydro-2-oxo-1H-thieno(3,4-d)imidaz- ole-4-pentanoic acid, DSSTox_RID_76688, DSSTox_GSID_22679, medobiotin, Deacura, Gabunat, Rombellin, Biokur, Biotin Gelfert, Biotin Hermes, Biotine Roche, Gelfert, Biotin, Biotin ratiopharm, Biotin-ratiopharm, Hermes, Biotin, Roche, Biotine, (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid, 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4b,6aalpha))-, 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid, Biotin (Vitamin B7), BTN, SMR000112255, D(+)Biotin, 1H-thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)-, 22879-79-4, Biotin [USP:INN:JAN], Biotin [USAN:INN:JAN], Biopeiderm, 5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, d-biotine, delta-Biotin, Vitamin-h, 1avd, 1ndj, 1stp, 1swg, 1swp, 2avi, 4bcs, 4ggz, 4jnj, 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)-, Bioepiderm (TN), CAS-58-85-5, Bios H, NCGC00094984-04, 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3as-(3aalpha,4beta,6aalpha)]-, Biotin111In, delta-(+)-Biotin, Biotin (8CI), delta-biotin factor s, 1df8, 1n9m, 2gh7, 3t2w, 4bj8, Prestwick0_000418, Prestwick1_000418, Prestwick2_000418, Prestwick3_000418, cid_253, BDBM12, bmse000227, CHEMBL857, D0P8TJ, Probes2_000006, AC1L57PN, SCHEMBL8763, BSPBio_000376, Biotin (JP17/USP/INN), MLS001066402, MLS001074888, MLS001331736, MLS001333089, D-Biotin, analytical standard, SPBio_002315, BPBio1_000414, cid_171548, GTPL4787, 5-((4S)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, DTXSID7022679, BIB0603, 1n43, 2f01, Biotin, >=99.0% (T), MolPort-002-507-373, YBJHBAHKTGYVGT-ZKWXMUAHSA-N, ZX-AFC000477, HMS1569C18, HMS2096C18, HMS2271O06, HMS3713C18, BB_NC-01320, HY-B0511, Tox21_113050, Tox21_302161, BBL028095, Biotin, tested according to Ph.Eur., GV4685, MFCD00005541, s3130, STK801941, ZINC35024346, AKOS001287669, Tox21_113050_1, CCG-220418, CS-2719, DB00121, EBD2202242, LS-3171, MCULE-7440963355, RP28663, Biotin, meets USP testing specifications, Biotin, SAJ special grade, >=98.0%, NCGC00179580-01, NCGC00179580-02, NCGC00179580-04, NCGC00255377-01, 56846-45-8, AC-19998, AJ-45752, BP-20441, BR-44010, CC-35623, KB-49599, SC-18448, ST055761, AB0068872, AX8021635, Biotin, >=99% (TLC), lyophilized powder, Biotin, Vetec(TM) reagent grade, >=99%, TL8003761, AB00374191, B0463, FT-0601580, ST24024711, 58B855, C00120, D00029, M02926, S-1412, AB00374191-08, AB00374191_11, Biotin, plant cell culture tested, >=99% (TLC), C-14824, SR-01000765521, Biotin, certified reference material, TraceCERT(R), Q-200929, SR-01000765521-2, BRD-K89210380-001-03-8, BRD-K89210380-001-13-7, 6AE43AA3-BC3D-4C49-9DB9-5913A2401EB6, Biotin, European Pharmacopoeia (EP) Reference Standard, F2173-0855, Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoate, Z210803762, Biotin, United States Pharmacopeia (USP) Reference Standard, cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valerate, (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valerate, 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, Daunorubicin hydrochloride, Antibiotic for Culture Media Use Only, (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valerate, Biotin, Pharmaceutical Secondary Standard; Certified Reference Material, 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)- (9CI), 5-((3aR,6S,6aS)-2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid, 5-[(3aR,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoic acid, hexahydro-2-oxo-[3aS-(3aa,4b,6aa)]-1H-Thieno[3,4-d]imidazole-4-pentanoate, hexahydro-2-oxo-[3aS-(3aa,4b,6aa)]-1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-[3as-(3alpha,4beta,6alpha)]-1H-Thieno[3,4-d]imidazole-4-pentanoate, hexahydro-2-oxo-[3as-(3alpha,4beta,6alpha)]-1H-Thieno[3,4-d]imidazole-4-pentanoic acid, 15720-24-8, 3672-05-7, 58073-87-3, BIOTIN, PharmaGrade, USP, meets FCC testing specifications, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production., Biotin, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99%

ID: 2670

chemical graph of compound 2670



InChIKey: YBVNFKZSMZGRAD-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N.C(CS(=O)(=O)O)O.C(CS(=O)(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8813
synonyms found at PubChem are:
PENTAMIDINE ISETHIONATE, 140-64-7, Pentamidine isethionate salt, Pentamidine diisethionate, 4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate), Pentamidine isetionate, Pentamidine (isethionate), UNII-V2P3K60DA2, Pneumopent, Lomidine, Nebupent, PENTAM, Pentam 300, Pentamidine isothionate, CHEBI:7977, V2P3K60DA2, 1,5-Bis(p-amidinophenoxy)pentane bis(2-hydroxyethanesulfonate salt), 4,4'-(Pentamethylenedioxy)dibenzamidine bis(2-hydroxyethanesulfonate), USAF XR-10, CCRIS 1660, 4,4'-Diamidino-alpha,omega-diphenoxypentane isethionate, NCGC00017022-05, CAS-140-64-7, 4,4'-Diamidinodiphenoxypentane di(beta-hydroxyethanesulfonate), EINECS 205-424-1, DSSTox_CID_3796, p,p'-(Pentamethylenedioxy)dibenzamidine bis(beta-hydroxyethanesulfonate), DSSTox_RID_77194, DSSTox_GSID_23796, Pentamidine diisetionate, W-108199, 2512 R.P., 4,4'-(pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethane-1-sulfonate), 4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate);4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate), bis(2-hydroxyethane-1-sulfonic acid); 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide, 4,4'-(Pentamethylenedioxy)-dibenzamidine bis(2-hydroxyethanesulfonate), SR-01000075174, Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-(1,5-pentanediylbis(oxy))bis(benzenecarboximidamide) (2:1), 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide bis(2-hydroxyethanesulfonic acid), Prestwick_857, Pentamidine isethionate [USAN:USP], Pentamidin-Isethionat, Pentaminide isetionate, PubChem20964, 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid, Benzamidine, 4,4'-(pentamethylenedioxy)di-, bis(beta-hydroxyethanesulfonate), Pentam 300 (TN), AC1L1RR1, AC1Q6X9Y, 4,4'-diamidino-a,w-diphenoxypentane isethionate, SCHEMBL33615, Pentamidine isetionate (JAN), SPECTRUM1500641, CHEMBL361506, Pentamidine isethionate (USAN), DTXSID5023796, CTK8B5397, HMS501D11, HY-B0537B, MolPort-003-665-497, HMS1569P07, HMS1921M19, HMS2096P07, HMS3713P07, C23H36N4O10S2, KS-00000Z9I, Pentamidine isethionate salt, powder, Tox21_110742, Tox21_201722, Tox21_300312, ANW-48586, CCG-39715, MFCD00079213, AKOS015914189, Tox21_110742_1, API0003784, CS-4133, KS-5289, MCULE-6357662093, NCGC00017022-01, NCGC00017022-02, NCGC00017022-03, NCGC00017022-04, NCGC00091927-01, NCGC00091927-02, NCGC00091927-03, NCGC00091927-04, NCGC00179034-07, NCGC00254121-01, NCGC00259271-01, BC221820, BR-51766, M808, AB0015398, AX8027505, ST2407516, TC-137331, 4CH-018037, FT-0631814, ST51006692, D00834, S-3112, 140P647, 4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd, C-23299, SR-01000075174-1, SR-01000075174-6, SR-01000075174-7, I14-45109, Z1558572531, 4,4'-(pentamethylenedioxy)dibenzamide bis(2-hydroxyethanesulfonate), 4,4'-(Pentamethylenedioxy)dibenzamidine bis-2-hydroxyethanesulfonate salt, 4,4'-(pentamethylenedioxy)dibenzamidine, bis-2-hydroxyethanesulfonate, Pentamidine diisetionate, European Pharmacopoeia (EP) Reference Standard, Pentamidine isethionate, United States Pharmacopeia (USP) Reference Standard, 1,5-bis[p-amidinophenoxy]pentane bis[2-hydroxyethanesulfonate salt] isethionate salt, 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide bis(2-hydroxyethylsulfonate), [pentane-1,5-diylbis(oxy-4,1-phenylene)]bis(aminomethaniminium) bis(2-hydroxyethanesulfonate), 4,4 inverted exclamation marka-(Pentamethylenedioxy)dibenzamidine bis(2-hydroxyethanesulfonate), 4-[5-(4-amidinophenoxy)pentyloxy]benzenecarboxamidine, 2-hydroxyethanesulfonic acid, 2-hydroxyethanesulfonic acid

ID: 2671

chemical graph of compound 2671



InChIKey: YCAXNWFCHTZUMD-UHFFFAOYSA-N
SMILES: CCC(C)(CN(C)C)OC(=O)C1=CC=CC=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10766
synonyms found at PubChem are:
Amylocaine hydrochloride, 532-59-2, Amyleine hydrochloride, Stovaine hydrochloride, Amylocaine HCl, (2-Benzoyloxy-2-methylbutyl)dimethylammonium chloride, EINECS 208-541-6, 1-(Dimethylamino)-2-methyl-2-butanol benzoate hydrochloride, 1-(Dimethylaminomethyl)-1-methylpropyl benzoate hydrochloride, 2-Dimethylamino-1-ethyl-1-methylethyl benzoate hydrochloride, Methylethyldimethylaminomethylcarbinol benzoyl ester hydrochloride, DSSTox_CID_25320, DSSTox_RID_80799, DSSTox_GSID_45320, 2-BUTANOL, 1-(DIMETHYLAMINO)-2-METHYL-, BENZOATE, HYDROCHLORIDE, Prestwick_24, Dolodent (TN), AC1L1VWE, NCGC00016494-01, CAS-532-59-2, SCHEMBL25684, MLS002154185, 644-26-8 (Parent), CHEMBL1718204, DTXSID1045320, HMS1568I19, Tox21_110455, 6214AF, Tox21_110455_1, API0016325, CCG-220049, NCGC00179641-03, LS-46516, SMR001233476, FT-0622377, D07572, SR-01000841239, Q-200639, SR-01000841239-2, [1-(dimethylamino)-2-methylbutan-2-yl] benzoate hydrochloride, 2-Butanol,1-(dimethylamino)-2-methyl-, 2-benzoate, hydrochloride (1:1), CTK4J7377, AKOS030255077, KB-205853

ID: 2672

chemical graph of compound 2672



InChIKey: YCGPBVPZHGYLBK-QFHYWFJHSA-N
SMILES: CC1C(=O)NC(C(=O)N/C(=C/NC(=O)N)/C(=O)NC(C(=O)NCC(C(=O)N1)N)C2CCN=C(N2)N)CNC(=O)CC(CCCN)N.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 78357828
synonyms found at PubChem are:
Capreomycin (sulfate), CS-3072, HY-17566

ID: 2673

chemical graph of compound 2673



InChIKey: YCIMNLLNPGFGHC-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 289
synonyms found at PubChem are:
pyrocatechol, catechol, 1,2-dihydroxybenzene, 120-80-9, 1,2-benzenediol, benzene-1,2-diol, pyrocatechin, 2-hydroxyphenol, o-Benzenediol, Pyrocatechine, o-Dihydroxybenzene, o-Dioxybenzene, o-Hydroquinone, o-Hydroxyphenol, o-Phenylenediol, Oxyphenic acid, Phthalhydroquinone, Fouramine PCH, Durafur developer C, Pelagol Grey C, benzenediol, Catechin (phenol), Fourrine 68, Benzene, o-dihydroxy-, Catechol (phenol), o-Diphenol, ortho-Hydroxyphenol, Pyrokatechin, Pyrokatechol, Katechol, ortho-Dihydroxybenzene, C.I. Oxidation Base 26, ortho-Benzenediol, ortho-Dioxybenzene, ortho-Hydroquinone, Katechol [Czech], ortho-Phenylenediol, Pyrocatechinic acid, NCI-C55856, Pyrokatechin [Czech], Pyrokatechol [Czech], CI Oxidation Base 26, UNII-LF3AJ089DQ, NSC 1573, C.I. 76500, CCRIS 741, Catechol-pyrocatechol, HSDB 1436, YCIMNLLNPGFGHC-UHFFFAOYSA-N, EINECS 204-427-5, BRN 0471401, LF3AJ089DQ, CI 76500, AI3-03995, CHEMBL280998, CHEBI:18135, CAQ, DSSTox_CID_257, DSSTox_RID_75468, DSSTox_GSID_20257, 12385-08-9, Phthalic alcohol, CAS-120-80-9, SMR000326660, Benzcatechin, Oxyphenate, Kachin, benzene diol, o Dihydroxybenzene, 4oow, alpha-hydroxyphenol, 1,2-benzenedio, o-dihydroxy-benzene, 2-hydroxyphenol[qr], phenol derivative, 2, 1,2-benzenediol[qr], 3fw4, 4k7i, ACMC-1BTYG, Pyrocatechol, >=99%, benzene,1,2-dihydroxy-, Lopac-C-9510, WLN: QR BQ, 1,2-dihydroxybenzene[qr], bmse000385, EC 204-427-5, 1,2-Dihydroxybenzene, XI, AC1L18WM, AC1Q78GA, 1,2-Benzenediol; Catechol, Lopac0_000280, SCHEMBL18351, Catechol, 99% 250g, KSC177E7T, MLS002153385, MLS002303022, BIDD:ER0327, Pyrocatechinic acidPyrocatechol, ai3-03995[qr], 1,2-benzenediol (pyrocatechol), DTXSID3020257, Pyrocatechol, p.a., 99.0%, BDBM26188, CTK0H7279, Durafur Developer CFouramine PCH, NSC1573, Benzene-1,2-diol (Pyrocatechol), MolPort-000-871-939, HMS2233A17, HMS3260H22, HMS3373K16, KS-000000NB, NSC-1573, Tox21_202317, Tox21_300153, Tox21_500280, ANW-17534, BBL002408, LS-637, MFCD00002188, SBB040792, STK398651, ZINC13512214, AKOS000119002, CCG-204375, DB02232, LP00280, MCULE-9007211544, RP18956, RTR-003436, TRA0043461, 1,2-Benzenediol, 1,2-Dihydroxybenzene, NCGC00015283-01, NCGC00015283-02, NCGC00015283-03, NCGC00015283-04, NCGC00015283-05, NCGC00015283-06, NCGC00015283-07, NCGC00015283-08, NCGC00091262-01, NCGC00091262-02, NCGC00091262-03, NCGC00253952-01, NCGC00259866-01, NCGC00260965-01, 37349-32-9, AJ-63991, AN-22835, BC205707, BP-21156, CJ-14403, KB-48701, SC-19023, AB1002105, Catechol (Pyrocatechol; Benzene-1,2-diol), DB-003770, ST2407554, TR-003436, EU-0100280, FT-0606411, P0317, P0567, ST50214346, T7344, Pyrocatechol; 1,2-Dihydroxybenzene; Catechol, 20244-21-7 (unspecified hydrochloride salt), 3437-EP2298767A1, 3437-EP2301934A1, 3437-EP2305633A1, 3437-EP2314587A1, C 9510, C00090, C01785, C15571, 1,2-Dihydroxybenzene, ReagentPlus(R), >=99%, 28696-EP2314579A1, Pyrocatechol, purified by sublimation, >=99.5%, A804599, AB-131/40235236, SR-01000075791, I01-2906, SR-01000075791-1, W-109068, F0001-0332, Pyrocatechol, certified reference material, TraceCERT(R), Z1262246103, InChI=1/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8, Pyrocatechol, plant cell culture tested, BioReagent, >=99%, powder, 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-,(2R-trans)-, 16474-89-8, 16474-90-1

ID: 2674

chemical graph of compound 2674



InChIKey: YCTJMCQNCJQTMG-AATRIKPKSA-N
SMILES: COC1=CC2=C(C=C1/C=C/C(=O)C3=CC(=C(C=C3OC)OC)OC)OCO2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 24002872
synonyms found at PubChem are:
Spectrum5_000331, 6-METHOXYPROSOGERIN B DIETHYL ETHER

ID: 2675

chemical graph of compound 2675



InChIKey: YCVPRTHEGLPYPB-VOTSOKGWSA-N
SMILES: C1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5280457
synonyms found at PubChem are:
Pinosylvin, 22139-77-1, Pinosylvine, 3,5-stilbenediol, trans-3,5-Dihydroxystilbene, (E)-5-Styrylbenzene-1,3-diol, 5-Styrylresorcinol, 102-61-4, (E)-5-(2-Phenylethenyl)-1,3-benzenediol, trans-pinosylvin, (E)-3,5-stilbenediol, 3,5-Stilbenediol, (E)-, UNII-881R434AIB, 5-(2-phenylethenyl)benzene-1,3-diol, NSC 362430, BRN 1870942, CHEMBL101506, CHEBI:17323, 1,3-Benzenediol, 5-(2-phenylethenyl)-, (E)-, 881R434AIB, 3,5-Dihydroxystilbene, 5-[(E)-2-phenylvinyl]benzene-1,3-diol, 5-[(E)-2-phenylethenyl]benzene-1,3-diol, 5-[(1E)-2-phenylethenyl]benzene-1,3-diol, pound inverted question markPinosylvin, (E)-pinosylvin, Stilbene, 1f, 1,3-Benzenediol,5-[(1E)-2-phenylethenyl]-, PubChem19089, AC1NQX1Y, AC1Q7AYY, Spectrum5_000307, (trans)-3,5-stilbenediol, C01745, BSPBio_001753, 3-06-00-05577 (Beilstein Handbook Reference), SCHEMBL454262, CHEBI:36011, MolPort-000-880-993, MolPort-044-723-416, ZINC901115, BCP18617, Pinosylvin, >=97.0% (HPLC), 5-[(E)-styryl]benzene-1,3-diol, 5-(2-phenylvinyl)benzene-1,3-diol, BDBM50045924, CCG-38399, LMPK13090001, NSC362430, Stilbene, 3,5-dihydroxy-, trans-, 5-(2-phenylethenyl)-1,3-benzenediol, AKOS000276828, AC-7928, NSC-362430, SDCCGMLS-0066433.P001, NCGC00179033-01, 1,3-Benzenediol, 5-(2-phenylethenyl)-, AK162490, BC657151, SC-20584, ZB015246, AX8015298, LS-146810, ST24035072, W2082, 1,3-Benzenediol, 5-[(1E)-2-phenylethenyl]-, 139P771, A815968, 5-[(E)-2-PHENYLETHENYL]-1,3-BENZENEDIOL, I14-6890, BRD-K94645280-001-02-1, D33B05BD-8441-4288-A247-D461C3D1F1CA, UNII-75IT683K8W component YCVPRTHEGLPYPB-VOTSOKGWSA-N

ID: 2676

chemical graph of compound 2676



InChIKey: YCWSUKQGVSGXJO-NTUHNPAUSA-N
SMILES: C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5337997
synonyms found at PubChem are:
Nifuroxazide, 965-52-6, Nifuroxazid, Dicoferin, Diarlidan, Ercefuryl, Nifuroxazida, Nifuroxazidum, Ercefurol, UNII-PM5LI0P38J, Nifuroxazidum [INN-Latin], Nifuroxazida [INN-Spanish], CCRIS 5490, RC 27109, p-Hydroxybenzoic acid (5-nitrofurfurylidene)hydrazide, R.C. 27-109, EINECS 213-522-0, BRN 1352180, PM5LI0P38J, MLS000069620, C12H9N3O5, 4-Hydroxy-N'-(5-nitrofurfuryliden)benzhydrazid, (Nitro-5' furfurylidene-2') hydroxy-4 benzhydrazide, 4-hydroxy-N-[(E)-(5-nitro-2-furyl)methyleneamino]benzamide, RC-27109, SMR000058185, (Nitro-5' furfurylidene-2') hydroxy-4 benzhydrazide [French], 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide, Benzoic acid, 4-hydroxy-, ((5-nitro-2-furanyl)methylene)hydrazide, BENZOIC ACID, p-HYDROXY-, (5-NITROFURFURYLIDENE)HYDRAZIDE, 5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone, p-Hydroxybenzoic acid 5-nitrofurfurylidene hydrazide, pentofuryl, Benzoic acid, 4-hydroxy-, [(5-nitro-2-furanyl)methylene]hydrazide, Benzoic acid, 4-hydroxy-, 2-[(5-nitro-2-furanyl)methylene]hydrazide, Nifuroxazide [INN:DCF], Nifuroxazide [INN:BAN:DCF], Prestwick_874, Nifuroxazide (INN), Opera_ID_40, AC1NSQ2Z, Prestwick2_000555, Prestwick3_000555, BSPBio_000629, 4-hydroxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide, SCHEMBL542542, SCHEMBL543480, ARONIS016368, BPBio1_000693, CHEMBL244888, SCHEMBL14608895, CHEBI:94556, CHEBI:135136, MolPort-000-565-540, MolPort-009-032-827, YCWSUKQGVSGXJO-NTUHNPAUSA-N, HMS1569P11, HMS2096P11, HMS3713P11, Pharmakon1600-01505788, HY-B1436, ZINC7997719, BDBM50396177, NSC759261, s4182, STK091243, STL454990, AKOS000483758, AC-8713, AN-7764, CCG-213989, CS-4918, NSC-759261, AS-13310, H868, LS-37645, SC-16466, BIM-0014420.P001, SBI-0014420.P002, TX-017860, AB00513861, SJ000287313, D07111, AB00513861_02, AB00513861_03, Nifuroxazide, VETRANAL(TM), analytical standard, 965N526, A845610, 4-Hydroxy-N'-(5-nitrofurfurylidene)-benzo-hydrazide, W-100139, BRD-K68188368-001-03-7, p-Hydroxybenzoic acid (5-nitrofurfurylidene) hydrazide, 4-hydroxy-benzoicaci((5-nitro-2-furanyl)methylene)hydrazide, 4-Dydroxy-N-[(E)-(5-nitro-2-furyl)methyleneamino]benzamide, 4-hydroxy-N'-[(1E)-(5-nitro-2-furyl)methylene]benzohydrazide, Nifuroxazide, European Pharmacopoeia (EP) Reference Standard, 4-hydroxy-N'-[(E)-(5-nitrofuran-2-yl)methylidene]benzohydrazide, 4-hydroxy-N-[(E)-(5-nitro-2-furanyl)methylideneamino]benzamide, N-[(E)-(5-nitrofuran-2-yl)methylideneamino]-4-oxidanyl-benzamide, 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylidene]benzenecarbohydrazonic acid, Benzoic acid, 4-hydroxy-, [(1E)-(5-nitro-2-furanyl)methylene]hydrazide, (nitro-5 inverted exclamation mark furfurylidene-2 inverted exclamation mark )hydroxy-4benzhydrazide

ID: 2677

chemical graph of compound 2677



InChIKey: YCXDDPGRZKUGDG-UHFFFAOYSA-L
SMILES: C1=C(C(=CC2=C1N=C(C(=N2)[O-])[O-])[N+](=O)[O-])C#N.[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2821
synonyms found at PubChem are:
CNQX disodium, 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE, NCGC00015198-01, Lopac-C-239, HMS3261M09, Tox21_500384, CCG-204478, LP00384, NCGC00015198-02, NCGC00015198-03, NCGC00015198-04, NCGC00093813-01, NCGC00093813-02, NCGC00261069-01, C-239, EU-0100384, CNQX disodium salt, 479347-85-8, disodium 6-cyano-7-nitroquinoxaline-2,3-diolate, 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE DISODIUM, SODIUM 6-CYANO-7-NITROQUINOXALINE-2,3-BIS(OLATE), 6-Quinoxalinecarbonitrile,1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-, 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt hydrate, AC1L1EJN, AC1O1BGU, AC1Q1UPU, ACMC-20d746, CHEMBL1255647, CTK4A9165, MolPort-003-940-680, HMS3267C06, BN0154, AKOS024456347, MB01477, B6567, 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE 2NA, J-003249, 1,2,3,4-TETRAHYDRO-7-NITRO-2,3-DIOXOQUINOXALINE-6-CARBONITRILE DISODIUM

ID: 2678

chemical graph of compound 2678



InChIKey: YCXRBCHEOFVYEN-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)OC)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281696
synonyms found at PubChem are:
Sciadopitysin, 521-34-6, Amentoflavone-7,4',4'''-trimethyl ether, NSC45108, CHEBI:9050, CHEMBL208908, YCXRBCHEOFVYEN-UHFFFAOYSA-N, 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one, 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4H-chromen-4-one, 7,4',4'''-Trimethylamentoflavone, EINECS 208-311-5, NSC 45108, SCIADOPITISIN, AC1NQYWY, C10182, SCHEMBL1158050, DTXSID30200096, MolPort-009-754-970, ZINC1531697, BDBM50323206, LMPK12040006, NSC-45108, AKOS030231209, MCULE-2539246408, Amentoflavone-7,4',4'''trimethylether, NCGC00163619-01, 4CN-1273, FT-0632283, W1534, C-57763, 4H-1-Benzopyran-4-one,5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-, 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1- benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4- benzopyrone, 5,7-Dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4-benzopyrone, 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxy-phenyl]-2-(4-methoxy-phenyl)-chromen-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-2-(4-methoxyphenyl)chromen-4-one

ID: 2679

chemical graph of compound 2679



InChIKey: YDGHCKHAXOUQOS-BTJKTKAUSA-N
SMILES: CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5282318
synonyms found at PubChem are:
Trimipramine maleate, 521-78-8, Trimipramine maleate salt, Surmontil maleate, Trimeprimine maleate, Trimipramine (maleate), Trimeprimine monomaleate, Trimipramini maleas, Trimipramium maleinicum, Trimipramine acid maleate, Trimipramine hydrogen maleate, C20H26N2.C4H4O4, EINECS 208-318-3, UNII-D28E1043W5, UNII-I412286V22, D28E1043W5, Surmontil (TN), I412286V22, 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine maleate (1:1), DSSTox_CID_25315, DSSTox_RID_80796, DSSTox_GSID_45315, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (Z)-2-butenedioate (1:1), 739-71-9 (Parent), 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, maleate (1:1), CHEBI:35030, 138283-60-0, 138283-61-1, SR-01000076152, Trimipramine maleate [USAN:JAN], (Z)-but-2-enedioic acid;3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine, Prestwick_1022, Trimipramine maleate [USAN:USP:JAN], Trimipraminhydrogenmaleat, AC1NQZV7, (+)-Trimipramine maleate, (-)-Trimipramine maleate, NCGC00016483-01, CAS-521-78-8, SCHEMBL41289, Trimipramine maleate, (+)-, Trimipramine maleate, (-)-, MLS001056765, Trimipramine Maleate (1:1), SPECTRUM1503117, CHEMBL1200948, DTXSID2045315, HMS500E15, MolPort-003-666-451, Trimipramine maleate (JAN/USAN), HMS1570B13, HMS1922G07, HMS2092L08, HMS2097B13, HMS2233H17, HMS3263H13, HMS3714B13, Pharmakon1600-01503117, HY-B1213, Tox21_110449, Tox21_501156, 2768AH, ACM521788, CCG-39308, MFCD00082376, NSC758386, AKOS026750012, Tox21_110449_1, CS-4840, LP01156, NSC-758386, NCGC00016013-06, NCGC00094418-01, NCGC00094418-02, NCGC00094418-03, NCGC00094418-04, NCGC00094418-05, NCGC00261841-01, AN-10861, LS-60411, SMR000326720, LS-173816, EU-0101156, C14029, D02408, T 3146, SR-01000076152-1, SR-01000076152-4, SR-01000076152-6, Trimipramine Maleate 1.0 mg/ml in Methanol (as free base), 10,11-Dihydro-N,N,|A-trimethyl-5H-dibenz[b,f]azepine-5-propanamine (2Z)-2-butenedioate, 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine; maleic acid, (Z)-but-2-enedioic acid; 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-, (2Z)-2-butenedioate (1:1), 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-, (Z)-2-butenedioate (1:1), 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (-)-, (2Z)-2-butenedioate (1:1), 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (-)-, (Z)-2-butenedioate (1:1), 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (2Z)-2-butenedioate (1:1), 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine (Z)-2-butenedioate (1:1), 5-[3-(dimethylammonio)-2-methylpropyl]-10,11-dihydro-5H-dibenzo[b,f]azepinium (2Z)-but-2-enedioate

ID: 2680

chemical graph of compound 2680



InChIKey: YDHTWQABZAECEX-RPWSLPDSSA-N
SMILES: CC(=O)OC1CC[C@@]2(C3CCC4C5CC(CCC5(CC[C@]4([C@@]3(CCC2C1(C)C)C)C)C(=O)O)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708668
synonyms found at PubChem are:
SPBio_001766, Spectrum_000582, SpecPlus_000389, AC1O8FIG, Spectrum2_001723, Spectrum3_001289, Spectrum4_001595, Spectrum5_000310, BSPBio_002897, KBioGR_002210, KBioSS_001062, DivK1c_006485, OLEANANOIC ACID ACETATE, KBio1_001429, KBio2_001062, KBio2_003630, KBio2_006198, KBio3_002117, CCG-38793, NCGC00178402-01, (6aR,6bR,12aR)-10-acetyloxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14,14a,14b-hexadecahydropicene-4a-carboxylic acid

ID: 2681

chemical graph of compound 2681



InChIKey: YDOTUXAWKBPQJW-NSLWYYNWSA-N
SMILES: CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=CNC7=CC=CC(=C67)C5=C4)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 134551
synonyms found at PubChem are:
alpha-Ergocryptine, Ergocryptine, Ergocryptine-alpha, 511-09-1, alpha-Ergokryptine, UNII-6WFB60157B, NSC 169479, Ergokryptine, CHEMBL1403281, CHEBI:10276, YDOTUXAWKBPQJW-NSLWYYNWSA-N, 12'-Hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione, 6WFB60157B, EINECS 208-121-2, 12'-hydroxy-2'-(1-methylethyl)-5'alpha-(2-methylpropyl)ergotaman-3',6',18-trione, 12'-hydroxy-5'alpha-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman, BRN 0078810, alpha ergocryptine, 12'-Hydroxy-2'-(1-methylethyl)-5'-alpha-(2-methylpropyl)ergotaman-3',6',18-trione, Prestwick_1063, Prestwick0_000727, Prestwick1_000727, Prestwick2_000727, Prestwick3_000727, Biomol-NT_000068, D06PXY, AC1L34SL, SCHEMBL78951, BSPBio_000654, GTPL271, MLS002153977, SPBio_002593, BPBio1_000720, BPBio1_001360, HMS1570A16, HMS2097A16, HMS2232C08, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'.alpha.)-, BDBM50390993, ZINC59796557, AKOS024282675, NSC 407319, SMR001233314, ST057581, C07545, C-44227, BRD-K74212935-001-03-1, UNII-2J09Y26C6I component YDOTUXAWKBPQJW-NSLWYYNWSA-N, (5'|A)-12'-Hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione, 12 inverted exclamation marka-Hydroxy-2 inverted exclamation marka-(1-methylethyl)-5 inverted exclamation marka-|A-(2-methylpropyl)ergotaman-3 inverted exclamation marka,6 inverted exclamation marka,18-trione, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'alpha)- (9CI)

ID: 2682

chemical graph of compound 2682



InChIKey: YDQWDHRMZQUTBA-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C=C(C=C3C2=O)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10207
synonyms found at PubChem are:
Aloe-emodin, Aloe emodin, 481-72-1, Aloeemodin, Rhabarberone, Aloe-emodine, EMODINE, 3-Hydroxymethylchrysazin, 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione, 3-Hydroxymethylchrysazine, 1,8-Dihydroxy-3-hydroxymethylanthraquinone, 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone, NSC 38628, 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione, UNII-C8IYT9CR7C, 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-, CCRIS 3526, EINECS 207-571-7, C8IYT9CR7C, 3-(Hydroxymethyl)chrysazin, BRN 2059062, CHEMBL40275, CHEBI:2607, 1,8-dihydroxy-3-hydroxymethyl-anthraquinone, YDQWDHRMZQUTBA-UHFFFAOYSA-N, NSC38628, 1,8-Dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone, Q-100526, ANTHRAQUINONE, 1,8-DIHYDROXY-3-HYDROXYMETHYL-, SMR000470920, aloe emodine, Aloe-emodol, Rottlerin?, Aloe-Emodine,(S), 1,8-dihydroxy-3-(hydroxymethyl)-9,10-anthrachinon, AC1L1UPK, D09BUG, AC1Q6JR7, DSSTox_CID_10695, DSSTox_RID_78855, DSSTox_GSID_30695, 4-08-00-03578 (Beilstein Handbook Reference), cid_10207, MLS000697563, MLS006011799, SCHEMBL309756, Aloe-emodin, analytical standard, DTXSID2030695, Aloe-emodin, >=95% (HPLC), MolPort-003-931-716, HMS3655N16, BCP28272, HY-N0189, ZINC4098644, Tox21_302400, AC-020, Aloeemodin:9,10-Anthracenedione,1,8-dihydroxy-3-(hydroxymethyl)-,, BBL027838, BDBM50085551, CA-417, CA0128, LMPK13040002, MFCD00017373, NSC-38628, s2259, STL146380, AKOS005720864, API0001418, CCG-208456, CS-3709, LS-2202, MCULE-6965338444, RP29614, 9, 1,8-dihydroxy-3-(hydroxymethyl)-, SMP2_000291, NCGC00163510-01, NCGC00163510-02, NCGC00163510-03, NCGC00255349-01, AJ-48016, AN-16215, AS-11638, BC216172, CAS-481-72-1, NCI60_003685, SC-46578, AB0010470, AX8006287, TL8003252, TR-031339, FT-0622062, N1851, ST24045939, Anthraquinone,8-dihydroxy-3-(hydroxymethyl)-, C10294, 481A721, Anthraquinone, 1,8-dihydroxy-3-(hydroxymethyl)-, SR-01000765772, I14-1413, SR-01000765772-3, 1,8-Dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone #, 1,8-Dihydroxy-3-hydroxymethyl-9,10-anthracenedione, 9CI, 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- (9CI), 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-hydroxymethyl-anthracene, Diacerein impurity B, European Pharmacopoeia (EP) Reference Standard, 1,8-Dihydroxy-3-(hydroxymethyl)-anthracene-9,10-dione (Aloe-Emodin), InChI=1/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H

ID: 2683

chemical graph of compound 2683



InChIKey: YDVKLIWOUGSPJK-NXENZQSYSA-N
SMILES: C[C@@]12CCC3[C@](C14C(O4)C(=O)O[C@H]2C5=COC=C5)([C@@H](CC6[C@@]3(C(=O)C[C@H](C6(C)C)O)C)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "DY Thomas" "D Zhang" "Y Luo" "R Robert" "KA Teske"


CID is 6708751
synonyms found at PubChem are:
KBio1_001755, Spectrum_000625, SpecPlus_000715, Spectrum2_000443, Spectrum3_000106, Spectrum4_001387, Spectrum5_000094, BSPBio_001692, BSPBio_001778, KBioGR_001714, KBioSS_001105, DivK1c_006811, SPBio_000486, KBio2_001105, KBio2_003673, KBio2_006241, KBio3_000812, CCG-38692, NCGC00179012-01, NCGC00179012-02

ID: 2684

chemical graph of compound 2684



InChIKey: YECHEDVCXXVLIY-UHFFFAOYSA-N
SMILES: COC1=C(C=C2CC3=CC(=C(C=C3CC4=CC(=C(C=C4CC2=C1)OC)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 273730
synonyms found at PubChem are:
Cyclotriveratrylene, Cycloveratril, Cycloveratryl, 1180-60-5, YECHEDVCXXVLIY-UHFFFAOYSA-N, 2,3,7,8,12,13-Hexamethoxy-10,15-dihydro-5H-tribenzo[a,d,g]cyclononene, NSC627660, 5H-Tribenzo[a,d,g]cyclononene,10,15-dihydro-2,3,7,8,12,13-hexamethoxy-, hexamethoxy[?], CYCLOVERATRYLENE, Spectrum_001174, AC1L6TKW, AC1Q4EZL, Spectrum3_001121, Spectrum4_001963, Spectrum5_000775, BSPBio_002581, KBioGR_002430, KBioSS_001654, SPECTRUM500123, AC1Q56P4, SCHEMBL4571013, CHEMBL1416784, KBio2_001654, KBio2_004222, KBio2_006790, KBio3_002081, DTXSID40297912, MolPort-001-759-734, ZINC1708918, CCG-46970, NSC119127, 5H-Tribenzo[a,d,g]cyclononene, 10,15-dihydro-2,3,7,8,12,13-hexamethoxy-, AKOS017343633, MCULE-8651736721, NSC-119127, NSC-627660, OR10845, SDCCGMLS-0066965.P001, NCGC00095972-01, NCGC00095972-02, ST50306917, SR-01000636633, SR-01000636633-1, SR-01000636633-2, BRD-K49154891-001-01-3, BRD-K49154891-001-02-1, 2,3,7,8,12,13-hexamethoxy-5,10,15-trihydrotribenzo[a,d,g][9]annulene, 5H-Tribenzo[a,g]cyclononene, 10,15-dihydro-2,3,7,8,12,13-hexamethoxy-, 2,3,7,8,12,13-Hexamethoxy-10,15-dihydro-5H-tribenzo[a,d,g]cyclononene #, 5,6,12,13,19,20-hexamethoxytetracyclo[15.4.0.0^{3,8}.0^{10,15}]henicosa-1(17),3(8),4,6,10(15),11,13,18,20-nonaene, 5,6,12,13,19,20-hexamethoxytetracyclo[15.4.0.0^{3,8}.0^{10,15}]henicosa-1(17),3,5,7,10,12,14,18,20-nonaene

ID: 2685

chemical graph of compound 2685



InChIKey: YEJCDKJIEMIWRQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3932
synonyms found at PubChem are:
Linopirdine, 105431-72-9, Dup 996, DuP-996, Linopirine, Linopirdine [USAN:INN], UNII-I5TB3NZ94T, AVIVA, 1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indolin-2-one, I5TB3NZ94T, NCGC00015590-03, CHEBI:34823, 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one, 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one, 1-Phenyl-3,3-bis(4-pyridinylmethyl)-2-indolinone, 2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-, DSSTox_CID_25163, DSSTox_RID_80713, 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one, DSSTox_GSID_45163, C26H21N3O, CAS-105431-72-9, SR-01000075324, Tocris-1999, Lopac-L-134, Linopirdine (USAN/INN), D08YHS, AC1L1H1B, 3,3-bis(4-pyridylmethyl)-1-phenylindolin-2-one, Lopac0_000732, MLS000862189, SCHEMBL122699, CHEMBL319111, GTPL2599, DTXSID6045163, CTK7H4905, Linopirdine, >=98% (HPLC), AOB5353, YEJCDKJIEMIWRQ-UHFFFAOYSA-N, HMS2233C05, HMS3262C06, HMS3370B17, ZINC537908, Tox21_110177, Tox21_500732, AKOS032946532, Tox21_110177_1, API0003182, CCG-204817, LP00732, NCGC00015590-01, NCGC00015590-02, NCGC00015590-04, NCGC00015590-05, NCGC00015590-06, NCGC00015590-07, NCGC00025338-01, NCGC00025338-02, NCGC00025338-03, NCGC00261417-01, AJ-23374, AN-25054, AS-16868, SMR000326952, TZ000890, ZB014350, LS-186894, LS-187548, CS-0039654, EU-0100732, Y5884, C13780, D04741, 3,3-Bis (4-pyridylmethyl)-1-phenylindolin-2-one, 3,3-bis(4-pyridinylmethyl)-1-phenylindolin-2-one, SR-01000075324-1, BRD-K59332007-300-01-9, 2H-Indol-2-one,1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-

ID: 2686

chemical graph of compound 2686



InChIKey: YEWGIGCYIAMFMA-UHFFFAOYSA-N
SMILES: CN1CCC2=CC=CC=C2CC3=C(CC1)C4=CC=CC=C4N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4350931
synonyms found at PubChem are:
LE 300, 274694-98-3, LE-300, CHEMBL441618, 7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine, L 8401, SR-01000075963, Tocris-1674, LE 300, solid, AC1N8VWD, Lopac-L-8401, D07YLK, Lopac0_000699, MLS002153328, SCHEMBL12610513, CHEBI:92030, CTK8E8452, DTXSID20402244, MolPort-003-958-572, YEWGIGCYIAMFMA-UHFFFAOYSA-N, HMS2233O19, HMS3262K19, HMS3268M15, HMS3372E16, ZINC1486281, Tox21_500699, BDBM50088341, BN0302, AKOS024456742, API0008482, CCG-204784, LP00699, NCGC00015614-01, NCGC00015614-02, NCGC00015614-03, NCGC00015614-04, NCGC00015614-05, NCGC00025255-01, NCGC00025255-02, NCGC00025255-03, NCGC00261384-01, ACM274694983, SMR001230741, RT-013566, B6824, EU-0100699, J-016773, SR-01000075963-1, SR-01000075963-3, BRD-K01648091-001-01-8, BRD-K01648091-001-04-2, 6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f][3]benzazecine, 7-Methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]-benzazecine, 7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecine, 7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azecino[5,4-b]indole(LE 300), 11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene, 3-Methyl-1,2,3,4,5,8-hexahydro-(14,15-[1,4]butanediylidene-(7,6-(iminoethano)-3-benzoazecine))-17-ene

ID: 2687

chemical graph of compound 2687



InChIKey: YEWHJCLOUYPAOH-UHFFFAOYSA-N
SMILES: C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 147514
synonyms found at PubChem are:
62717-42-4, SKF38393 HCl, SKF 38393 hydrochloride, SKF-38393 hydrochloride, SKF 38393 (hydrochloride), (+/-)-SKF-38393 hydrochloride, 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride, 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, hydrochloride, CHEMBL542700, 81633-77-4, 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrochloride, (+/-)-SKF-38393, SR-01000075378, SKF 38393A, 159795-65-0, AC1L3VC1, MLS000859931, SKF 38393 HCl, SKF-38393 HCl, SCHEMBL3425787, (y)-SKF-38393 hydrochloride, AOB5359, (?)-SKF-38393 hydrochloride, MolPort-003-940-903, YEWHJCLOUYPAOH-UHFFFAOYSA-N, SKF-38393A, BCP28880, Tox21_500436, 2,3,4,5-Tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol hydrochloride, BN0484, HY-12520A, MFCD00069248, NSC320959, AKOS016012197, CCG-221740, CS-5354, LP00436, NSC-320959, NCGC00093856-01, NCGC00261121-01, AS-16874, LS-28000, SMR000326792, AX8246769, KB-219640, D-047, EU-0100436, S7993, (+/-)-SKF-38393 Hydrochloride, Crystalline, ( inverted question mark)-SKF-38393 hydrochloride, SR-01000075378-1, ( inverted exclamation markA)-SKF38393 hydrochloride, (+/-)-SKF-38393 hydrochloride, crystalline, >=98% (HPLC), (+/-)-1-Phenyl-2,3,4-tetrahydro(1H)-3-benzapezine-7,8-diol HCl, 5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrochloride, (+/-)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride, (+/-)-1-Phenyl-2,3,4-tetrahydro(1H)-3-benzapezine-7,8-diol hydrochloride, ( inverted exclamation markA)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride, ( inverted question mark)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride

ID: 2688

chemical graph of compound 2688



InChIKey: YEZNLOUZAIOMLT-UHFFFAOYSA-N
SMILES: CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 610479
synonyms found at PubChem are:
tolfenamic acid, 13710-19-5, Clotam, N-(3-Chloro-2-methylphenyl)anthranilic acid, 2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid, Tolfedine, Acido tolfenamico, Acide tolfenamique, Acidum tolfenamicum, Tolfine, GEA 6414, N-(2-Methyl-3-chlorophenyl)anthranilic acid, UNII-3G943U18KM, N-(3-Chloro-o-tolyl)-anthranilic acid, 2-(3-Chloro-2-methylanilino)benzoic acid, Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-, Anthranilic acid, N-(3-chloro-o-tolyl)-, CHEBI:32243, 3G943U18KM, NCGC00016705-05, Bifenac, CAS-13710-19-5, 2-(3-chloro-2-methylphenylamino)benzoic acid, 2-((3-Chloro-2-methylphenyl)amino)benzoic acid, DSSTox_CID_25409, DSSTox_RID_80860, DSSTox_GSID_45409, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid, SR-01000000102, Tolfenamic, Prestwick_579, Clotam (TN), Spectrum_001263, ACMC-209cat, Tolfenamic acid, NSAID, AC1LD1MD, Prestwick0_000205, Prestwick1_000205, Prestwick2_000205, Prestwick3_000205, Spectrum2_001446, Spectrum3_001762, Spectrum4_000238, Spectrum5_001143, AC1Q2F9Y, Oprea1_692996, SCHEMBL25190, Tolfenamic acid (JAN/INN), BSPBio_000189, BSPBio_003223, KBioGR_000935, KBioSS_001743, flufenamic acid analogue, 32, MLS000028531, BIDD:GT0343, SPECTRUM1501198, SPBio_001311, SPBio_002110, BPBio1_000209, CHEMBL121626, cid_610479, GTPL8769, ZINC2188, DTXSID1045409, BDBM35905, KBio2_001743, KBio2_004311, KBio2_006879, KBio3_002723, YEZNLOUZAIOMLT-UHFFFAOYSA-, MolPort-002-904-064, YEZNLOUZAIOMLT-UHFFFAOYSA-N, HMS1568J11, HMS1921P13, HMS2090D04, HMS2095J11, HMS2230J13, HMS3370A02, HMS3651E06, HMS3712J11, Pharmakon1600-01501198, HY-B0335, KS-00000H6I, Tox21_110570, ANW-20211, CCG-39189, NSC757873, s1959, SBB058187, AKOS012836098, Tox21_110570_1, 2-(3-Chloro-o-toluidino)benzoic Acid, API0002084, CS-2377, DB09216, MCULE-9901889833, NSC-757873, SEL10850963, 2(3-Chloro-2-methylanilino)benzoic acid, NCGC00016705-01, NCGC00016705-02, NCGC00016705-03, NCGC00016705-04, NCGC00016705-06, NCGC00016705-07, NCGC00016705-10, NCGC00022587-03, NCGC00022587-04, NCGC00022587-05, AS-13748, BC218925, DA-11289, n-(3-chloro-ortho-tolyl)anthranilic acid, SMR000058289, SBI-0051687.P002, AB0032595, AB2000392, TC-108956, 2-(3-Chloro-2-methylanilino)benzoic acid #, AB00052244, FT-0652603, ST51015128, UNM000001237003, X5948, D01183, J10240, AB00052244-15, AB00052244_16, AB00052244_17, A807198, Benzoic acid, 2-(3-chloro-2-methylphenylamino)-, 2-[(3-chloranyl-2-methyl-phenyl)amino]benzoic acid, J-006962, SR-01000000102-2, SR-01000000102-3, Tolfenamic acid, VETRANAL(TM), analytical standard, BRD-K50133271-001-05-4, BRD-K50133271-001-10-4, Benzoic acid, 2-((3-chloro-2-methylphenyl)amino)- (9CI), Tolfenamic acid, European Pharmacopoeia (EP) Reference Standard, Tolfenamic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)

ID: 2689

chemical graph of compound 2689



InChIKey: YFCUZWYIPBUQBD-ZOWNYOTGSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 73093
synonyms found at PubChem are:
4272-74-6, TLCK hydrochloride, TLCK, (S)-N-(7-Amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochloride, (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, Tos-Lys-chloromethylketone HCl, N-alpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride, EINECS 224-266-4, Na-p-Tosyl-L-lysine chloromethyl ketone hydrochloride, NCGC00094434-01, Tosyl-L-lysyl-chloromethane hydrochloride, L-N-(5-Amino-1-(chloroacetyl)pentyl)-p-toluenesulfonamide hydrochloride, p-Toluenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-, hydrochloride, L-, 2364-87-6, (S)-N-(5-Amino-1-(chloroacetyl)pentyl)-4-methylbenzenesulfonamide monohydrochloride, Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-, monohydrochloride, (S)-, DSSTox_CID_25807, DSSTox_RID_81145, DSSTox_GSID_45807, 4238-41-9, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride, (S)-N-(5-Amino-1-(chloroacetyl)pentyl)-p-toluenesulphonamide monohydrochloride, CAS-4272-74-6, SR-01000076171, EINECS 224-199-0, Benzenesulfonamide,N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-, Tosyllysine chloromethylketone hydrochloride, Tosyl-L-lysine chloromethylketone hydrochloride, 1-Chloro-3-tosylamido-7-amino-2-hepta none hydrochloride, MLS000859917, C14H22Cl2N2O3S, AC1L2J98, C14H21ClN2O3S hydrochloride, CHEMBL1256974, DTXSID3045807, SCHEMBL11406948, BIT3073, p-N-(7-Amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide, Tos-Lys-chloromethylketone . HCl, MolPort-003-895-956, ZX-AFC000027, KS-000019DA, Tox21_111280, Tox21_501180, AKOS024319626, AKOS024465073, Tox21_111280_1, ACM2364876, CCG-207871, LP01180, Tos-Lys-chloromethylketone hydrochloride, NCGC00162359-04, NCGC00261865-01, AK163781, AS-46909, SMR000326778, AX8294904, HY-112716, LS-154096, CS-0062851, EU-0101180, ST24036360, X6888, 1-Chloro-3-tosylamido-7-amino-L-2-heptanone, K-8802, T 7254, SR-01000076171-1, SR-01000076171-5, (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone HCl, Nalpha-Tosyl-L-lysine chloromethyl ketone hydrochloride, (3S)-7-Amino-1-chloro-3-tosylamino-2-heptanone hydrochloride, (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, 98%, Nalpha-Tosyl-L-lysine chloromethyl ketone hydrochloride, >=99.0% (AT), N-[(3S)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide hydrochloride, Nalpha-Tosyl-L-lysine chloromethyl ketone hydrochloride, >=96% (TLC), powder

ID: 2690

chemical graph of compound 2690



InChIKey: YFCWKIXGWIMLAM-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C(=CC(=NC2=C1)NC3=CC=CC=C3)C)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "N Pedemonte" "GL Lukacs" "LJ Galietta" "O Zegarra-Moran" "AS Verkman" "K Du"


CID is 740918
synonyms found at PubChem are:
4,5,7-trimethyl-N-phenylquinolin-2-amine, AC1LERUR, Oprea1_716671, SCHEMBL837742, MolPort-002-944-470, ZINC178560, STK091440, AKOS001640147, MCULE-4314803191, EU-0010423, Phenyl-(4,5,7-trimethyl-quinolin-2-yl)-amine

ID: 2691

chemical graph of compound 2691



InChIKey: YFGHCGITMMYXAQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4236
synonyms found at PubChem are:
modafinil, 68693-11-8, Provigil, Modiodal, Modafinilum [Latin], 2-(Benzhydrylsulfinyl)acetamide, 2-[(diphenylmethyl)sulfinyl]acetamide, Modafinilo [Spanish], Modafinilum, Alertec, Modafinilo, Sparlon, Modafinil [USAN:INN], (+-)-Modafinil, CRL 40476, CRL-40476, 2-((Diphenylmethyl)sulfinyl)acetamide, Moderateafinil, Modavigil, 2-benzhydrylsulfinylacetamide, CEP 1538, CHEMBL1373, DEA No. 1680, CHEBI:77585, 2-(diphenylmethyl)sulfinylacetamide, CEP-1538, Modafinil D5, NCGC00095176-03, Acetamide, 2-((diphenylmethyl)sulfinyl)-, DSSTox_CID_3329, DSSTox_RID_76980, DSSTox_GSID_23329, C15H15NO2S, 112111-49-6, Acetamide, 2-[(diphenylmethyl)sulfinyl]-, SMR000058957, CAS-68693-11-8, UNII-152JRG3T0U, SR-01000759419, 152JRG3T0U, modaphonil, Attenace, Modalert, Modasomil, CRL 40983, HSDB 7585, Modafinil [USAN:USP:INN:BAN], Provigil (TN), (+/-)-Modafinil, Modafinil, (+)-, Acetamide, 2-((S)-(diphenylmethyl)sulfinyl)-, AC1L1HPP, Spectrum2_001712, D07HQC, SCHEMBL34488, BSPBio_002270, MLS000759427, MLS001424049, Modafinil (JAN/USAN/INN), BIDD:GT0714, SPECTRUM1505361, (-)benzhydrylsulphinylacetamide, SPBio_001724, ACE069, GTPL7555, NH 02D, NH-02D, DTXSID0023329, Modafinil, >=98% (HPLC), 2-diphenylmethanesulfinylacetamide, AFT-801, YFGHCGITMMYXAQ-UHFFFAOYSA-N, HMS1922F12, HMS2051P17, HMS2093D15, HMS3264I03, HMS3393P17, HMS3713C12, Pharmakon1600-01504283, Pharmakon1600-01505361, 2-(diphenylmethane)sulfinylacetamide, 2-(diphenylmethyl)sulfinylethanamide, AOB87710, BCP28422, Tox21_111470, BDBM50156055, CCG-39511, CN-801, CRL-40983, HY-15201A, MFCD00868082, NSC751178, NSC751850, NSC758711, NSC759110, 2-[di(phenyl)methylsulfinyl]acetamide, Modafinil 1.0 mg/ml in Acetonitrile, AKOS004118314, Tox21_111470_1, 2-(Diphenyl-methanesulfinyl)-acetamide, AC-1382, API0003414, CS-2191, DB00745, MCULE-6678415272, NC00224, NSC-751178, NSC-751850, NSC-758711, NSC-759110, NCGC00095176-01, NCGC00095176-02, NCGC00095176-04, NCGC00095176-05, NCGC00095176-06, NCGC00095176-08, AN-38078, AS-17039, BC208846, BR-49128, CPD000058957, SAM001246587, SC-74637, SBI-0206841.P001, AB0021223, KB-226631, LS-176682, TL8004816, AM20060710, FT-0602599, ST45021999, D01832, S-3878, AB00639993_03, AB00639993_04, 693M118, A836219, C-45684, L001269, I06-0190, SR-01000759419-3, SR-01000759419-4, BRD-A16332958-001-02-4, BRD-A16332958-001-04-0, F2173-0797, Modafinil, European Pharmacopoeia (EP) Reference Standard, Modafinil for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 2692

chemical graph of compound 2692



InChIKey: YFYNOWXBIBKGHB-FBCQKBJTSA-N
SMILES: C1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 104766
synonyms found at PubChem are:
(1S,3R)-ACPD, 1S,3R-ACPD, (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid, trans-ACPD, 111900-32-4, 1-Amino-1,3-dicarboxycyclopentane, CB 1712, trans-(+/-)-ACPD, CHEMBL34453, (1S,3S)-ACPD, 1-Aminocyclopentane-1S,3R-dicarboxylic acid, (1S,3R)-1-ACPD, cis-ACPD, t-ACPD, 1-Amino-1,3-cyclopentanedicarboxylic acid, 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S,3R)-, 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S-cis)-, MLS002153209, ACPD, SR-01000597678, SMR001230688, ACPD-1S,3R, trans-(y)-ACPD, trans-(?)-ACPD, 1-aminocyclopentyl-1,3-dicarboxylic acid, AC1L2XGH, AC1Q5QYM, trans-1-aminocyclopentane-1,3-dicarboxylate, cis-1-amino-1,3-cyclopentanecarboxylic acid, (trans)-1-aminocyclopentyl-1,3-dicarboxylate, D04DKM, 1,3-Cyclopentanedicarboxylicacid, 1-amino-, (1S,3R)-, 1-amino-cyclopentyl-trans-1S,3R-dicarboxylate, trans-(1S,3R)-ACPD, Lopac0_000097, trans-( )-ACPD monohydrate, 1-amino-1,3-dicarboxycyclopentane, (trans)-isomer, SCHEMBL179741, GTPL1365, 1-amino-1,3-dicarboxycyclopentane, (cis)-(+-)-isomer, 1-amino-1,3-dicarboxycyclopentane, cis-(1R,3R)-isomer, 1-amino-1,3-dicarboxycyclopentane, cis-(1S,3S)-isomer, BDBM66976, CTK0H3900, YFYNOWXBIBKGHB-FBCQKBJTSA-, 1-amino-1,3-dicarboxycyclopentane, (trans)-(+-)-isomer, 1-amino-1,3-dicarboxycyclopentane, trans-(1R,3S)-isomer, cid_16218853, MolPort-003-940-060, HMS3260C16, 67684-64-4, ZINC2004213, Tox21_500097, BN0051, FCH839908, PDSP1_000813, PDSP2_000800, AKOS017344535, trans-( inverted question mark)-ACPD, CCG-204192, LP00097, NCGC00024488-03, NCGC00024488-04, NCGC00024488-05, NCGC00260782-01, LS-57947, A-155, B6220, B6245, EU-0100097, FT-0639513, FT-0639514, FT-0695375, FT-0695378, SR-01000075420, (1S,3S)-1-amino-1,3-cyclopentanedicarboxylic acid, I04-8357, J-500447, J-500459, SR-01000075420-1, SR-01000597678-1, SR-01000597678-2, (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;hydrate, trans-(1S,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid, (1S,3R)-1-azanylcyclopentane-1,3-dicarboxylic acid;hydrate, trans-( inverted question mark)-1-Amino-1,3-cyclopentanedicarboxylic acid, 130942-93-7, 149881-50-5, 27-84-9, C5b, InChI=1/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m1/s1

ID: 2693

chemical graph of compound 2693



InChIKey: YFZOUMNUDGGHIW-UHFFFAOYSA-M
SMILES: C1=CC(=CC=C1C(=O)O)[Hg]Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1730
synonyms found at PubChem are:
4-chloromercuribenzoic acid, p-Chloromercuribenzoic acid, PCMB, p-Chloromercurybenzoic acid, P-(CHLOROMERCURI)BENZOIC ACID, p-Chloromercuric benzoic acid, (p-carboxyphenyl)chloromercury, C-5150, (4-carboxyphenyl)-chloro-mercury, SR-01000075767, 4-Chloromercuribenzoate, C7H5HClgO2, Lopac-C-5913, WLN: QVR D-HG-G, AC1Q5TU8, DSSTox_CID_20725, DSSTox_RID_79572, DSSTox_GSID_40725, Lopac0_000275, SCHEMBL53888, MLS002153251, 4-(Hydroxymercuri)benzoic acid, AC1L1C40, (4-carboxyphenyl)-chloromercury, DTXSID8040725, Benzoic acid, p-(chloromercuri), CHEBI:28420, CTK5H1241, YFZOUMNUDGGHIW-UHFFFAOYSA-M, NSC32866, ZX-AT011541, Tox21_301861, 7833AF, NSC-32866, (4-carboxyphenyl)mercury(II) chloride, AKOS004910380, CCG-204370, LP00275, CAS-59-85-8, NCGC00015248-01, NCGC00015248-02, NCGC00015248-03, NCGC00015248-04, NCGC00093732-01, NCGC00093732-02, NCGC00164252-01, NCGC00255501-01, CC-18913, SMR001230705, TR-032819, EU-0100275, FT-0618221, C 5913, C03444, C-33496, SR-01000075767-1, SR-01000075767-3, I01-10396, 4-Chloromercuribenzoic acid, cysteine active site modifier, Chloromercuribenzoate, p-Chlormercuribenzoic acid, Chloromercuribenzoic acid, UNII-E1LE0WZ4BO, NSC 32866, E1LE0WZ4BO, p-Chloro-mercuric benzoic acid, EINECS 200-442-6, Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen, AI3-15315, (4-Carboxylatophenyl)chloromercurate(1-), hydrogen, AC1L1LOI, AC1Q1RQQ, LS-89688, A11258, 107296-30-0, 130973-93-2, 1356399-46-6, 136969-76-1, 139116-12-4, 145757-52-4, 172906-39-7, 75344-65-9, 77329-67-0, 792952-75-1, 856770-63-3

ID: 2694

chemical graph of compound 2694



InChIKey: YGCODSQDUUUKIV-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1Cl)N=C(O2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6103
synonyms found at PubChem are:
Zoxazolamine, 61-80-3, 2-Amino-5-chlorobenzoxazole, 5-chlorobenzo[d]oxazol-2-amine, 5-Chloro-1,3-benzoxazol-2-amine, Flexin, 2-Benzoxazolamine, 5-chloro-, Contrazole, Deflexol, Flexilon, Zoxamin, Zoxine, USAF MA-12, McN-485, 5-Chloro-2-benzoxazolamine, Zossazolamina [DCIT], C7H5ClN2O, Zoxazolaminum [INN-Latin], Zoxazolamina [INN-Spanish], NSC 24995, UNII-9DOW362Q29, BENZOXAZOLE, 2-AMINO-5-CHLORO-, CHEBI:35053, EINECS 200-519-4, AI3-63120, MLS002639033, YGCODSQDUUUKIV-UHFFFAOYSA-N, 9DOW362Q29, CAS-61-80-3, NCGC00016280-02, DSSTox_CID_25245, DSSTox_RID_80772, DSSTox_GSID_45245, 5-chlorobenzoxazole-2-ylamine, Zossazolamina, Zoxazolamina, Zoxazolaminum, SMR001233162, SR-05000001893, Zoxazolamine [INN:BAN], Zoxaxzolamine, Zoxazolamine [INN:BAN:NF], Prestwick_897, PubChem12473, Spectrum_001749, SpecPlus_000767, Prestwick0_000328, Prestwick1_000328, Prestwick2_000328, Prestwick3_000328, Spectrum2_000771, Spectrum3_001663, Spectrum4_000624, Spectrum5_001390, D0N0LB, AC1L1LT9, AC1Q3MT5, AC1Q52ZZ, 5-chloro-2-aminobenzoxazole, 2-Benzoxazolamine,5-chloro-, 5-Chlorobenzoxazol-2-ylamine, BSPBio_000335, BSPBio_003445, KBioGR_001208, KBioSS_002229, 2-amino-5--chlorobenzoxazole, MLS002153778, DivK1c_006863, SCHEMBL251567, SPECTRUM1504216, SPBio_000842, SPBio_002256, 5-chloro-benzooxazol-2-ylamine, BPBio1_000369, CHEMBL472566, GTPL2327, DTXSID1045245, BCBcMAP01_000023, CTK5B3744, KBio1_001807, KBio2_002229, KBio2_004797, KBio2_007365, KBio3_002665, MolPort-000-150-982, WLN: T56 BN DOJ CZ HG, HMS1569A17, HMS1922F21, HMS2093C16, HMS2096A17, HMS2234O12, HMS3371M19, HMS3652N17, HMS3713A17, Pharmakon1600-01504216, ALBB-018399, HY-B1307, KS-000018UI, NSC24995, ZINC8614810, 2-Amino-5-chlorobenzoxazole, 97%, Tox21_110346, 9267AB, ANW-58181, BBL023547, BDBM50127011, CCG-40150, MMV003270, NSC-24995, NSC758690, s4233, SBB003874, STL290662, 2-Benzoxazolamine, 5-chloro- (9CI), 5-Chloro-1,3-benzoxazol-2-amine #, AKOS001063493, Tox21_110346_1, NSC-758690, RL04341, SMP1_000323, NCGC00016280-01, NCGC00016280-03, NCGC00016280-04, NCGC00016280-05, NCGC00016280-07, NCGC00095114-01, NCGC00095114-02, NCGC00095114-03, NCGC00095114-04, AJ-57745, AN-41834, KB-42922, LS-42127, SC-15015, TS-02286, SBI-0052854.P002, AB0049173, DB-027769, TC-146926, AB00053350, CS-0013070, FT-0611160, R1128, ST45026642, EN300-13203, C13841, AB00053350_09, AB00053350_10, 005A770, I14-4834, J-517385, SR-05000001893-1, SR-05000001893-3, BRD-K66353228-001-04-7, BRD-K66353228-001-05-4, BRD-K66353228-001-08-8, InChI=1/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10, 36R

ID: 2695

chemical graph of compound 2695



InChIKey: YGEIMSMISRCBFF-UHFFFAOYSA-M
SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)N3C=C[N+](=C3)CC(C4=C(C=C(C=C4)Cl)Cl)OCC5=C(C=C(C=C5)Cl)Cl)Cl.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 644274
synonyms found at PubChem are:
calmidazolium chloride, 57265-65-3, R 24571, 1-[bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride, MLS002172477, CHEMBL1208858, SMR001254103, SR-01000075486, R 24571 chloride, AC1LD8WO, methoxy]ethyl]-, chloride, Calmidazolium chloride, solid, MLS006010820, SCHEMBL1020756, CTK8F8430, AOB2162, MolPort-023-276-485, HMS2230P23, HMS3260H06, HMS3269B13, HMS3372E22, Tox21_500272, MFCD00077679, AKOS024457168, CCG-221576, LP00272, NCGC00093729-01, NCGC00093729-02, NCGC00260957-01, SMR004701750, KB-271651, EU-0100272, C 3930, SR-01000075486-1, SR-01000075486-5, 1-[bis(p-Chlorophenyl)methyl]-3-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl], 1-[Bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-|A-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride, 1-[Bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride, 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazol-3-ium chloride, 1H-imidazolium, 3-[bis(4-chlorophenyl)methyl]-1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl), 3-[bis(4-chlorophenyl)methyl]-1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazol-1-ium chloride, Compound R24571, [1-bis -p-chlorophenyl) methyl]-3-[2,4-dichloro- beta-(2,4-dichlorobenzyloxy) phenyl]-imidazolium chloride, Compound R24571, [1-bis-p-chlorophenyl) methyl]-3-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy) phenyl]-imidazolium chloride

ID: 2696

chemical graph of compound 2696



InChIKey: YGKPIROTKVQCCU-UHFFFAOYSA-N
SMILES: C1CCN(CC1)CCOC(=O)C2=CNC3=CC=CC=C32

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3272300
synonyms found at PubChem are:
SB 203186, SB-203186, 2-piperidin-1-ylethyl 1H-indole-3-carboxylate, NCGC00015921-01, Tocris-0785, Lopac-S-0443, Biomol-NT_000150, D0E8KS, AC1MN68M, Lopac0_000347, GTPL255, BPBio1_000617, SCHEMBL1041116, CHEMBL1255781, BDBM85778, CHEBI:92477, ZINC14457, YGKPIROTKVQCCU-UHFFFAOYSA-N, CCG-204442, NCGC00015921-02, NCGC00015921-03, NCGC00015921-04, NCGC00024790-01, NCGC00024790-02, NCGC00024790-03, CAS_135938-17-9, (1-piperidinyl)ethyl 1h-indole 3-carboxylate, 2-(1-piperidyl)ethyl 1H-indole-3-carboxylate, 2-(1-Piperidyl)ethyl 1 H-indole-3-carboxylate, L005299, BRD-K27141178-001-01-0, BRD-K27141178-003-02-4, 1H-Indole-3-carboxylic acid 2-piperidin-1-yl-ethyl ester

ID: 2697

chemical graph of compound 2697



InChIKey: YGRFXPCHZBRUKP-UHFFFAOYSA-N
SMILES: CC(C(C1=C(C=CC(=C1)OC)OC)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6081
synonyms found at PubChem are:
METHOXAMINE HYDROCHLORIDE, 61-16-5, Methoxamine HCl, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol hydrochloride, Idasal, MLS000069686, Methoxamine hydrochloride [JAN], Vasoxyl hydrochloride, Vasylox hydrochloride, Pressomin hydrochloride, 2-Amino-1-(2,5-dimethoxyphenyl)-1-propanol hydrochloride, NCGC00094108-02, SMR000058479, Methoxamini hydrochloridum, Methoxamine hydrochloride (JAN), HSDB 3362, alpha-[1-Aminoethyl]-2,5-dimethoxybenzyl alcohol, EINECS 200-499-7, 1-(2,5-Dimethoxyphenyl)-2-aminopropanol, DL-2-Amino-1-(2,5-dimethoxyphenyl)propanol hydrochloride, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol;hydrochloride, alpha-(1-Aminoethyl)-2,5-dimethoxybenzenemethanol hydrochloride, SR-01000000198, (+-)-alpha-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride, alpha-(alpha-Aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride, Benzenemethanol, alpha-(1-aminoethyl)-2,5-dimethoxy-, hydrochloride, Benzyl alcohol, alpha-(1-aminoethyl)-2,5-dimethoxy-, hydrochloride, beta-(2,5-Dimethoxyphenyl)-beta-hydroxyisopropylamine hydrochloride, beta-Hydroxy-beta-(2,5-dimethoxyphenyl)-isopropylamine hydrochloride, Prestwick_866, Vasoxyl (TN), Methoxamine hydrochlorid, Opera_ID_389, AC1L1LRF, CAS-61-16-5, DSSTox_CID_25782, DSSTox_RID_81124, DSSTox_GSID_45782, MLS001074122, MLS002222272, SCHEMBL146117, SPECTRUM1500399, CHEBI:6840, CHEMBL1201103, DTXSID7045782, CTK8G0838, MolPort-003-666-230, YGRFXPCHZBRUKP-UHFFFAOYSA-N, HMS1569L11, HMS1920N03, Pharmakon1600-01500399, BCP19863, Tox21_111248, Tox21_500769, CCG-38999, MFCD00058607, NSC757102, AKOS017343946, API0003335, LP00769, MCULE-8719716451, NSC-757102, NCGC00094108-01, NCGC00094108-03, NCGC00094108-04, NCGC00094108-05, NCGC00261454-01, LS-42643, EU-0100769, FT-0603257, ST51015059, X0381, D01020, M 6524, 058M607, A833069, C-15154, SR-01000000198-2, SR-01000000198-6, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol, chloride, Z2756841808, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol,hydrochloride, 2-azanyl-1-(2,5-dimethoxyphenyl)propan-1-ol hydrochloride, alpha-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol hydrochloride, Methoxamine hydrochloride, United States Pharmacopeia (USP) Reference Standard, AC1LCWAO, AKOS026749996, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol; hydron; chloride

ID: 2698

chemical graph of compound 2698



InChIKey: YGWFCQYETHJKNX-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 14634
synonyms found at PubChem are:
Rhinactin, Olynth, Neo-Synephrine II, EINECS 214-936-4, 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline monohydrochloride, UNII-X5S84033NZ, 2-IMIDAZOLINE, 2-(4-tert-BUTYL-2,6-DIMETHYLBENZYL)-, MONOHYDROCHLORIDE, 1H-Imidazole, 2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydro-, monohydrochloride, X5S84033NZ, Xylometazoline hydrochloride [USP], Otrivin hydrochloride, 1H-Imidazole, 2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydro-, hydrochloride (1:1), AC1L248X, 526-36-3 (Parent), CX-004, LS-79582, 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazol-1-ium chloride, 28096-10-8, 8057-34-9, AC1LCW8F, AKOS026749771, 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole; hydron; chloride, Xylometazoline hydrochloride, 1218-35-5, Xylometazoline HCl, 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride, Xylometazoline (hydrochloride), MLS000069695, SMR000058526, DSSTox_CID_25223, DSSTox_RID_80760, DSSTox_GSID_45223, 2-[(4-tert-butyl-2,6-dimethyl-phenyl)methyl]-4,5-dihydro-1H-imidazole hydrochloride, 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole hydrochloride, Xylometazoline hydrochloride (USP), SR-01000000230, NCGC00016101-02, CAS-1218-35-5, 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1h-imidazole hydrochloride, stas hydrochloride, otrivinhydrochloride, otrivinehydrochloride, Prestwick_574, AC1NQZZM, 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride, 1H-Imidazole, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-, hydrochloride (1:1), Opera_ID_1744, xylometazolin hydrochloride, Neo-Synephrine II (TN), SCHEMBL41837, MLS001076518, SPECTRUM1500614, CHEMBL1256400, DTXSID3045223, CTK4B2768, MolPort-001-768-551, REGID_for_CID_5282386, YGWFCQYETHJKNX-UHFFFAOYSA-N, HMS1568N07, HMS1921K09, Pharmakon1600-01500614, Xylometazoline Hydrochloride ,(S), BCP22148, HY-B0475, Tox21_110305, Tox21_501269, ANW-41892, CCG-39900, MFCD00238707, NSC757378, s2576, AKOS015895456, Tox21_110305_1, AC-8301, AN-8175, API0006284, CS-2589, KS-5144, LP01269, NSC-757378, NCGC00016101-10, NCGC00094506-01, NCGC00094506-02, NCGC00094506-03, NCGC00094506-04, NCGC00094506-05, NCGC00261954-01, H812, AB0013278, AB1009546, KB-223225, TR-003540, EU-0101269, FT-0603554, D00757, K-1647, X 6000, Xylometazoline hydrochloride, analytical standard, 218X355, A804796, I06-0599, J-004686, SR-01000000230-2, SR-01000000230-7, 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazolinmonohydrochloride, Xylometazoline hydrochloride, British Pharmacopoeia (BP) Reference Standard, Xylometazoline hydrochloride, European Pharmacopoeia (EP) Reference Standard, 2-(4-(tert-butyl)-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazole hydrochloride, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1h-imidazol, Xylometazoline hydrochloride, United States Pharmacopeia (USP) Reference Standard

ID: 2699

chemical graph of compound 2699



InChIKey: YHKBUDZECQDYBR-UHFFFAOYSA-L
SMILES: CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C.[Br-].[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5965
synonyms found at PubChem are:
DEMECARIUM BROMIDE, 56-94-0, Humorsol, Frumtosnil, Tosmicil, Tosmilen, Tosmilene, Visumatic, Visumiotic, Tonilen, Demekastigmine bromide, Demecarii bromidum, Demekarium bromide, Bromuro de demecario, Bromure de demecarium, demecastigmine, Demecarii bromidum [INN-Latin], BC 48, UNII-61D5V4OKTP, Bromure de demecarium [INN-French], Bromuro de demecario [INN-Spanish], Humorsol (TN), Demecarium bromide [INN:BAN], HSDB 2168, EINECS 200-301-9, 61D5V4OKTP, (m-Hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate), Decamethylenebis(N-methylcarbamic acid m-dimethylaminophenyl ester) bromomethylate, N,N'-Bis(3-trimethylammoniumphenoxycarbonyl)-N,N'-dimethyldecamethylenediamine dibromide, CHEBI:4391, Demecarium bromide (USP/INN), Decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate) dimethobromide, (m-Hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate) (2:1), Ammonium, (m-hydroxyphenyl)trimethyl-, bromide, decamethylenebis(methylcarbamate) (2:1), decamethylenebis[m-dimethylaminophenyl n-methylcarbamate] dimethobromide, Ammonium, (m-hydroxyphenyl)trimethyl-, bromide, decamethylenebis(methylcarbamate), 3,3'-(((Decane-1,10-diylbis(methylazanediyl))bis(carbonyl))bis(oxy))bis(N,N,N-trimethylbenzenaminium) bromide, Benzenaminium, 3,3'-(1,10-decanediylbis((methylimino)carbonyloxy))bis(N,N,N-trimethyl-, dibromide, decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate)dimethobromide, (m-Hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate) (7CI), 3,3'-{decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide, trimethyl-[3-[methyl-[10-[methyl-[3-(trimethylazaniumyl)phenoxy]carbonylamino]decyl]carbamoyl]oxyphenyl]azanium dibromide, demecarium dibromide, Demecarium bromide [USP:INN:BAN], trimethyl-[3-[methyl-[10-[methyl-[3-(trimethylazaniumyl)phenoxy]carbonylamino]decyl]carbamoyl]oxyphenyl]azanium;dibromide, AC1L1LIL, D06IDT, AC1Q1R6E, SCHEMBL34283, C32H52Br2N4O4, CHEMBL1200514, MolPort-005-943-446, HMS2096L14, HMS3713L14, BCP24065, AC-305, AN-443, AKOS015896671, CCG-220616, C21H36N2O2.C12H18N2O2, AS-11735, BC226412, CC-26330, LS-18445, FT-0698614, D00667, C-23655, SR-01000838877, I06-2187, SR-01000838877-2, W-105496, 3,3'-(decane-1,10-diylbis(methylazanediyl))bis(oxomethylene)bis(oxy)bis(N,N,N-trimethylbenzenaminium) bromide, Benzenaminium,3,3'-(1,10-decanediylbis((methylimino)carbonyloxy))bis(N,N,N-trimethyl-, dibromide, trimethyl-[3-[methyl-[10-[methyl-[3-(trimethylammonio)phenoxy]carbonyl-amino]decyl]carbamoyl]oxyphenyl]ammonium dibromide

ID: 2700

chemical graph of compound 2700



InChIKey: YHSTYYHRDFATAQ-XURVNGJNSA-N
SMILES: C[C@H]1[C@H](CC[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@H]2O)C3=C(C4=C(C=C3)C(=O)C5=C(C4=O)C=C[C@]6([C@@]5(C(=O)C[C@](C6)(C)O[C@H]7CC[C@@H]([C@@H](O7)C)O[C@H]8C=CC(=O)[C@@H](O8)C)O)O)O)C)O[C@H]9C=CC(=O)[C@@H](O9)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 73213
synonyms found at PubChem are:
vineomycin a1, Vineomycin A(sub 1), Antibiotic OS 4742 A(sub 1), OS-4742 A1, P 1894B, BRN 5724539, 78164-00-8, Vineomycin, P-1894B, AC1L2JGN, AC1Q6CNI, (3R,4aR,12bS)-4a,8,12b-trihydroxy-9-[(2R,4R,5S,6R)-4-hydroxy-6-methyl-5-[(2S,5S,6S)-6-methyl-5-[[(2R,6S)-6-methyl-5-oxo-2H-pyran-2-yl]oxy]oxan-2-yl]oxyoxan-2-yl]-3-methyl-3-[(2S,5S,6S)-6-methyl-5-[[(2R,6S)-6-methyl-5-oxo-2H-pyran-2-yl]oxy]oxan-2-yl]oxy-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, LS-27927, SR-05000002221, SR-05000002221-2, (3R,4aR,12bS)-4a,8,12b-trihydroxy-9-[(2R,4R,5S,6R)-4-hydroxy-6-methyl-5-[(2S,5S,6S)-6-methyl-5-[[(2R,6S)-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]-3-methyl-3-[(2S,5S,6S)-6-methyl-5-[[(2R,6S)-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydropyran-2-yl]oxy-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, 66220-21-1

ID: 2701

chemical graph of compound 2701



InChIKey: YHYNDFTUZMEYNX-UHFFFAOYSA-N
SMILES: CC1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957580
synonyms found at PubChem are:
1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine dihydrochloride, Iso-H-7, Dihydrochloride, 140663-38-3, ISO-H7, IN1301, 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl, SR-01000075940, EU-0100662, SCHEMBL1321843, CHEMBL1412973, CTK8E3058, DTXSID90474690, YHYNDFTUZMEYNX-UHFFFAOYSA-N, Tox21_500662, LP00662, NCGC00094024-01, NCGC00261347-01, KB-147541, RT-018130, FT-0626847, I 6391, J-007414, SR-01000075940-1, SR-01000075940-2, 5-(3-methylpiperazin-1-ylsulfonyl)isoquinoline dihydrochloride, 1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine dihydrochloride (H7), 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE

ID: 2702

chemical graph of compound 2702



InChIKey: YIEIZLQDUWWSED-ICXZMCDNSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@](C=C[C@H](C2(C)C)O)(C3[C@@]1(C4=CC(=O)O[C@H]([C@@]4(CC3)C)C5=COC=C5)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708714
synonyms found at PubChem are:
KBio1_001631, Spectrum_000682, SpecPlus_000591, Spectrum2_000260, Spectrum3_000048, Spectrum4_001330, Spectrum5_000179, AC1O8FL8, BSPBio_001775, KBioGR_001799, KBioSS_001162, SPECTRUM100190, DivK1c_006687, SPBio_000080, SCHEMBL9973673, 3-alpha-HYDROXYDEOXYGEDININ, KBio2_001162, KBio2_003730, KBio2_006298, KBio3_000935, CCG-39820, SDCCGMLS-0066282.P001, NCGC00179014-01, [(1R,4bR,5R,8R,10aS,12aR)-1-(furan-3-yl)-8-hydroxy-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,10b,11,12-octahydronaphtho[2,1-f]isochromen-5-yl] acetate

ID: 2703

chemical graph of compound 2703



InChIKey: YIQRSAKVWZVLDN-QZTNRIJFSA-N
SMILES: C[C@@H]1CC(=O)CC(=O)[C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 71317160
synonyms found at PubChem are:
Griseofulvic acid, 469-54-5, (+/-)-Griseofulvic Acid, CHEMBL3138677, YIQRSAKVWZVLDN-QZTNRIJFSA-N, AKOS027326717, ZINC100122094, Spiro(benzofuran-2(3H),1'-cyclohexane)-2',3,4'-trione, 7-chloro-4,6-dimethoxy-6'-methyl-, trans-, FT-0669058, (1'S,6'R)-7-Chloro-4,6-dimethoxy-6'-methyl-,Spiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione, (2S,6'R)-7-Chloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione, trans-7-Chloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione

ID: 2704

chemical graph of compound 2704



InChIKey: YIVXMZJTEQBPQO-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1489
synonyms found at PubChem are:
4-(2,4-Dichlorophenoxy)butanoic acid, 94-82-6, 2,4-DB, Butoxone, Butyrac, 4-(2,4-DICHLOROPHENOXY)BUTYRIC ACID, 2,4-D butyric acid, Legumex D, Butormone, Buratal, Butirex, Butoxon, Butoxone ester, Butyrac ester, Butyrac 118, Butyrac 200, Sys 67 Buratal, Butoxone amine, Butanoic acid, 4-(2,4-dichlorophenoxy)-, Caswell No. 316, 2,4-DM, gamma-(2,4-Dichlorophenoxy)butyric acid, NSC 70337, UNII-SL314DW868, CCRIS 1021, 2,4-DB [BSI:ISO], Butyric acid, 4-(2,4-dichlorophenoxy)-, HSDB 6603, 2,4-(Dichlorophenoxy)butyric acid, 4-(2,4-DB), EINECS 202-366-9, EPA Pesticide Chemical Code 030801, Kyselina 4-(2,4-dichlorfenoxy)maselna, BRN 1976809, CHEBI:73173, Kyselina 4-(2,4-dichlorfenoxy)maselna [Czech], YIVXMZJTEQBPQO-UHFFFAOYSA-N, SL314DW868, (2,4-Dichlorophenoxy)butyric acid, NCGC00094532-06, gamma-(2,4-dichlorophenoxy)butanoic acid, gamma-(2,4-dichlorophenoxy)-butyric acid, .gamma.-(2,4-Dichlorophenoxy)butyric acid, gamma-(2,4-dichlorophenoxy)-butanoic acid, 2,4-DB (4-(2,4-Dichlorophenoxy)butanoic Acid), Venceweed, Embutox klean-up, Embutox (Salt/Mix), 2,4-D Butyric, Embutone (Salt/Mix), Campbell's db straight, Spectrum_001855, Embutox E (Salt/Mix), SpecPlus_000466, AC1L1BLF, Spectrum2_001854, Spectrum3_000833, Spectrum4_000673, Spectrum5_001980, DSSTox_CID_4035, Dichlorophenoxy)butyric acid, WLN: QV3OR BG DG, AC1Q75IZ, DSSTox_RID_77263, DSSTox_GSID_24035, BSPBio_002385, KBioGR_001105, KBioSS_002372, SPECTRUM330041, 4-06-00-00927 (Beilstein Handbook Reference), MB 2878 (Salt/Mix), MLS002207204, DivK1c_006562, SCHEMBL116448, SPBio_001668, CHEMBL1892377, DTXSID7024035, CTK7J3913, KBio1_001506, KBio2_002368, KBio2_004936, KBio2_007504, KBio3_001885, Butyric acid,4-dichlorophenoxy)-, MolPort-000-224-386, Butanoic acid,4-dichlorophenoxy)-, NSC70337, ZINC1696211, 19480-40-1 (potassium salt), Tox21_400080, 5654AF, BBL015279, CCG-39392, NSC-70337, SBB003160, STK107020, 10433-59-7 (hydrochloride salt), 2,4-dichloro-4-phenoxy-butanoic acid, AKOS000104014, MCULE-5266190327, 2,4-DB 10 microg/mL in Acetonitrile, CAS-94-82-6, 2,4-DB 100 microg/mL in Acetonitrile, 4-(2,4-Dichloro-phenoxy)-butyric acid, NCGC00094532-01, NCGC00094532-02, NCGC00094532-03, NCGC00094532-04, NCGC00094532-05, NCGC00094532-07, AJ-30301, AN-42709, BC202079, LS-47946, SMR000777852, gamma-2,4-DICHLOROPHENOXYBUTYRIC ACID, 2,4-DB, PESTANAL(R), analytical standard, FT-0616499, H3012, ST50051678, C14404, Butanoic acid, 4-(2,4-dichlorophenoxy)- (9CI), W-100182, 2,4-DB, certified reference material, TraceCERT(R), BRD-K69188402-001-04-2, I14-20035, Z57252704, 4-(2,4-Dichlorophenoxy)butyric acid, analytical standard

ID: 2705

chemical graph of compound 2705



InChIKey: YJGVMLPVUAXIQN-HAEOHBJNSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 72435
synonyms found at PubChem are:
Picropodophyllin, Picropodophyllotoxin, 477-47-4, AXL1717, Picropodophyllin (PPP), IGF-1R Inhibitor, PPP, NSC 36407, UNII-0F35AOI227, AXL1717 (Picropodophyllotoxin), NSC36407, 17434-18-3, BRN 0099161, CHEBI:75251, 0F35AOI227, C22H22O8, Insulin-like Growth Factor-1 Receptor Inhibitor, (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5-alpha,5a-alpha,8a-alpha,9-alpha))-, 4354-76-1, AXL 1717, Spectrum_001636, Picropodophyllin (8CI), Spectrum2_000520, Spectrum3_001671, Spectrum4_001836, Spectrum5_000631, AC1L2I2M, BSPBio_003481, KBioGR_002538, KBioSS_002116, SCHEMBL159598, SPECTRUM1504410, SPBio_000479, (-)PPP, CHEMBL283120, GTPL7873, KBio2_002116, KBio2_004684, KBio2_007252, KBio3_002701, DTXSID80197245, MolPort-003-665-514, YJGVMLPVUAXIQN-HAEOHBJNSA-N, HMS1923O05, BCP18482, KS-00000TA3, ZINC4098919, CCG-39920, IN1989, NSC-36407, s7668, AKOS015965529, CS-1184, DB12802, SDCCGMLS-0066757.P001, NCGC00161923-01, NCGC00161923-02, NCGC00161923-04, AC-20289, AJ-48021, HY-15494, LS-70860, SC-94922, X1203, Picropodophyllotoxin, >=96% (HPLC), powder, W-5271, BRD-K81829253-001-02-9, BRD-K81829253-001-03-7, Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer, WLN: T E5 C665 FVO NO PO OHTT&&J DR CO1 DO1 EO1& JQ, (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0?,?.0??,??]hexadeca-1(9),2,7-trien-12-one, (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one, (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, (5R,5aS,8aR,9R)-9-Hydroxy-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)furo[3 inverted exclamation marka,4 inverted exclamation marka:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, (5R,5aS,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, [5R-(.alpha.-5a.alpha.,8a.alpha.,9.alpha.)], Furo[3',7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.alpha.,8a.alpha.,9.alpha.)]-

ID: 2706

chemical graph of compound 2706



InChIKey: YJGVMLPVUAXIQN-XVVDYKMHSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10607
synonyms found at PubChem are:
podophyllotoxin, Podofilox, 518-28-5, Condylox, Condyline, Wartec, Podophyllinic acid lactone, Podophyllotoxin 7, Warticon, (-)-Podophyllotoxin, Podophyllum, Podofilox [USAN], CCRIS 565, UNII-L36H50F353, HSDB 7238, NSC24818, CHEMBL61, EINECS 208-250-4, NSC 24818, AI3-50456, MLS000069495, (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, CHEBI:50305, Podofilox (USAN), L36H50F353, 4354-76-1, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-, NCGC00022001-05, Podofilm, SMR000059121, C22H22O8, EN300-52746, DSSTox_CID_25645, DSSTox_RID_81023, DSSTox_GSID_45645, (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one, (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one, Podocon-25, Podophilox, (5R,9R,5aR,8aR)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,9,5a,8a-pentahydro-2H -isobenzofurano[5',6'-2,1]benzo[4,5-d]1,3-dioxolan-6-one, 1,3,3a,4,9,9a-Hexahydro-9-hydroxy-6,7-(methylenedioxy)-4-(3',4',5'-trimethoxyphenyl)benz(f)isobenzofuran-3-one, SR-05000001749, MLS002702981, CPH86, Podofillina, Podophylotoxin, Mayapple isolate, NSC-24818, Condylox (TN), CAS-518-28-5, Podophyllum (resin), Podophyllotoxin,(S), Prestwick_1018, Podofillina [Italian], podophyllinicacidlactone, Podophyllotoxin (BAN), Podophyllotoxin, 95%, PubChem20017, Spectrum_000199, AC1L1VKA, Opera_ID_1397, Prestwick0_000782, Prestwick1_000782, Prestwick2_000782, Prestwick3_000782, Spectrum2_000878, Spectrum4_000592, Spectrum5_001368, D0D4HN, D0SK5B, UPCMLD-DP035, AC1Q47JV, SCHEMBL42243, BSPBio_000884, BSPBio_002352, KBioGR_001084, KBioSS_000679, MLS001148204, MLS002172467, MLS006010754, MLS006011412, BIDD:GT0123, DivK1c_000292, UNII-16902YVY2B, SPBio_000955, SPBio_002823, BPBio1_000974, CCRIS 4391, DTXSID3045645, UPCMLD-DP035:001, UPCMLD-DP035:002, BCBcMAP01_000165, CTK6J6283, HMS500O14, KBio1_000292, KBio2_000679, KBio2_003247, KBio2_005815, MolPort-002-493-753, NINDS_000292, YJGVMLPVUAXIQN-XVVDYKMHSA-N, 16902YVY2B, HMS1570M06, HMS2093P16, HMS2097M06, HMS2235A23, HMS3259J19, HMS3714M06, Pharmakon1600-02300332, 9-Hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5ah)-one, ALBB-020906, BB_NC-01063, BCP24085, Podophyllotoxin, analytical standard, ZINC3861806, EINECS 232-546-2, Tox21_110874, Tox21_202922, B18-5C, BBL033695, BDBM50035218, CCG-39894, CP0089, MFCD00075290, NSC759591, STK801918, AKOS000265559, Tox21_110874_1, AC-1656, CS-1185, DB01179, KS-1281, MCULE-9617461427, NC00675, ND-1185, NSC-759591, RL03911, SDCCGMLS-0066888.P001, IDI1_000292, SMP1_000243, NCGC00022001-03, NCGC00022001-07, NCGC00022001-08, NCGC00022001-09, NCGC00022001-10, NCGC00022001-11, NCGC00022001-13, NCGC00022001-14, NCGC00260468-01, AJ-46241, AN-14707, BC202956, CC-33854, CPD000059121, HY-15552, KB-62928, LS-70859, NCI60_001981, RD4-6269, SAM002548978, SC-47262, SC-77494, ST066914, AB0012227, FT-0603436, ST24048942, C10874, D05529, P-6980, W-5067, 70339-EP2305243A1, 70339-EP2308833A2, 518P285, A828801, C-21968, SR-01000003030, SR-01000003030-3, SR-05000001749-1, SR-05000001749-2, BRD-K47869605-001-05-6, BRD-K47869605-001-18-9, Z1258578359, (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0;{3,7}.0;{11,15}]hexadeca-1(9),2,7-trien-12-one, (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0?,?.0??,??]hexadeca-1(9),2,7-trien-12-one, (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one, (5R,5aR,8aR,9R)-5-oxidanyl-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one, 11016-28-7, 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, [5R-(5.alpha.,5a.beta.,8a.alpha.,9.alpha.)], 8050-60-0, 8061-07-2, 8063-20-5, furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)-, Furo[3',7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.beta.,8a.alpha.,9.alpha.)]-, Naphtho[2,3-dioxole-6-carboxylic acid, 5,6,7,8-tetrahydro-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl-, .gamma.-lactone

ID: 2707

chemical graph of compound 2707



InChIKey: YJNLRCNFLREHBK-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC3(C(O3)CCC2(C)OC)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3344818
synonyms found at PubChem are:
2-METHOXY-5 (6)EPOXY-TETRAHYDROCARYOPHYLLENE, KBio2_001184, AC1MOJZV, Spectrum_000704, SpecPlus_000230, Spectrum2_001772, Spectrum3_001247, Spectrum4_001458, Spectrum5_000075, BSPBio_002754, KBioGR_001975, KBioSS_001184, SPECTRUM300111, DivK1c_006326, SPBio_001663, CHEMBL1488390, KBio1_001270, KBio2_003752, KBio2_006320, KBio3_002254, CCG-38421, SDCCGMLS-0066559.P001, NCGC00095586-01, NCGC00095586-02, SR-05000002498, SR-05000002498-1

ID: 2708

chemical graph of compound 2708



InChIKey: YJYGOWVFDGULLL-UHFFFAOYSA-N
SMILES: CN=C1N=C(N(S1)C2=CC=CC=C2)C3=CC=CC=C3.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9884675
synonyms found at PubChem are:
AKOS003611634, SCH-202676 hydrobromide, SCH-202676, CHEMBL536950, 265980-25-4, N-(2,3-DIPHENYL-1,2,4-THIADIAZOL-5(2H)-YLIDENE)METHANAMINE HYDROBROMIDE, 70375-43-8, MLS002153327, N-(2,3-Diphenyl-1,2,4-thiadiazol-5-(2H)-ylidene)methanamine, HBr, (Z)-N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)methanamine hydrobromide, N-(2,3-diphenyl-1,2,4-thiadiazol-5-(2H)-ylidene)methanamine hydrobromide, SMR001230740, SCH 202676 hydrobromide, CHEMBL3913449, SCHEMBL15824571, AOB5563, MolPort-003-177-839, YJYGOWVFDGULLL-UHFFFAOYSA-N, Tox21_501078, SCH-202676 hydrobromide, 98%, AKOS024456575, CCG-222382, LP01078, MCULE-9664951339, NCGC00094356-01, NCGC00094356-02, NCGC00261763-01, EU-0101078, S 4063, SR-01000076133, SR-01000076133-2, F3066-0002

ID: 2709

chemical graph of compound 2709



InChIKey: YKBGVTZYEHREMT-KVQBGUIXSA-N
SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC(=NC3=O)N)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 187790
synonyms found at PubChem are:
2'-deoxyguanosine, deoxyguanosine, 961-07-9, Guanine deoxyriboside, 2-Deoxyguanosine, Guanosine, 2'-deoxy-, Guanine deoxy nucleoside, 2'-DEOXY-GUANOSINE, 2;-Deoxyguanosine, UNII-G9481N71RO, 663615-45-0, Guanine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-, 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9H-Purin-6-ol, 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-, CHEBI:17172, G9481N71RO, 9-(2-Deoxy-b-D-erythro-pentofuranosyl)guanine, C00330, 38559-49-8, 2(acute)-Deoxyguanosine, 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, EINECS 213-505-8, NSC 22837, 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one, 9-[(4S,2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-imino-1,3-dihydropurin -6-one, CGP, GNG, Deoxyguanosine-14C, Guanine-2'-deoxyriboside, deoxy-guanosine, NSC22837, DGua, 19916-78-0, 2'-Desoxyguanosine, 9-(2-Deoxy-beta-D-ribofuranosyl)guanine, 2'-deoxy guanosine, 2a8g, 2''''-Deoxyguanosine, bmse000003, AC1L4LJ5, SCHEMBL20615, 961-07-9 (anhydrous), CHEMBL68908, CTK1C4229, CTK4E2719, guanosine-1-15N, 2'-deoxy-, MolPort-009-683-201, YKBGVTZYEHREMT-KVQBGUIXSA-N, ZINC404256, 116002-28-9, ACT02951, 2'-Deoxyguanosine monohydrate (dG), 3177AH, ANW-51699, BBL000985, BDBM50422404, MFCD00150760, SBB003059, STK361810, AKOS001715540, AKOS025116629, AKOS025117348, Guanosine,2'-deoxy-,monohydrate(9ci), CS-3151, MCULE-5458121764, RP29521, VZ21866, guanosine-N,1,3-15N3, 2'-deoxy-, guanosine-N,1,7-15N3, 2'-deoxy, NCGC00161975-01, AJ-22294, BR-75712, HY-17563, KB-18535, SC-09157, SC-83576, ST055520, ST066876, Guanosine, 2'-deoxy- (6CI,8CI,9CI), AB0213764, DB-006105, guanosine-1,3,7,9-15N4, 2'-deoxy-, D0052, Guanosine, 2'-deoxy-, labeled with carbon-14, guanosine-2-13C-N,1,7-15N3, 2'-deoxy, S-7530, 9-(2-deoxy-b-D-erythro-pentofuranosyl)-Guanine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine, I07-008, SR-01000147728, SR-01000147728-1, 9-(2-deoxy-beta-delta-erythro-pentofuranosyl)-Guanine, 9-(2-Deoxy-beta-delta-erythro-pentofuranosyl)guanine, 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol, 452E7995-3178-4132-A1ED-F81A3701094B, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one, 6H-purin-6-one, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,9-dihydro-, 6H-Purin-6-one,2-amino-9-(2-deoxy-a-D-erythro-pentofuranosyl)-1,9-dihydro-, 9-[(4S,2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-aminohydropurin-6-one, 123173-08-0, 130434-96-7, 197227-97-7, 197227-99-9, 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one, 244769-88-8, 246137-64-4, 77074-27-2

ID: 2710

chemical graph of compound 2710



InChIKey: YKJYKKNCCRKFSL-RDBSUJKOSA-N
SMILES: CC(=O)O[C@@H]1[C@H](CN[C@@H]1CC2=CC=C(C=C2)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 253602
synonyms found at PubChem are:
anisomycin, 22862-76-6, Flagecidin, (-)-Anisomycin, TCMDC-125504, UNII-6C74YM2NGI, NSC76712, NSC-76712, (2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate, (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate, Upjohn 204t3, 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate, 6C74YM2NGI, MLS001066392, Anisomycin,streptomyces griseolus, Anisomycin, Streptomyces griseolus, CHEBI:338412, 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate, Antibiotic PA-106, SMR000471874, [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate, 2-p-Methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidine, 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, EINECS 245-269-7, NSC 76712, (2R,3S,4S)-2-((4-Methoxyphenyl)methyl)-3,4-pyrrolidinediol 3-acetate, (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R,3S,4S)-, 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)-, BRN 0020705, ANM, AI3-50846, SR-01000597397, GNF-Pf-4549, (2R,3S,4S)-2-(p-Methoxyphenylmethyl)-3-acetoxy-4-hydroxypyrrolidine, 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, 3-acetate, (2S,3R,4R)-, 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2alpha,3alpha,4beta))-, 6185-RBK-10, (-) Anisomycin, 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2-alpha,3-alpha,4-beta))-, Spectrum_001534, AC1L5OGT, Prestwick3_000412, Spectrum2_000632, Spectrum4_000748, Spectrum5_001495, AC1Q1L8A, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, CBiol_002064, BSPBio_000364, BSPBio_001436, KBioGR_001076, KBioSS_002014, ZINC954, 5-21-05-00523 (Beilstein Handbook Reference), DivK1c_000855, SPECTRUM1503906, SPBio_000624, (2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, BPBio1_000402, CHEMBL423192, cid_253602, SCHEMBL2270183, DTXSID5040966, BDBM63919, HMS502K17, KBio1_000855, KBio2_002014, KBio2_004582, KBio2_007150, BIA4315, MolPort-003-666-504, NINDS_000855, YKJYKKNCCRKFSL-RDBSUJKOSA-N, ZX-AFC000035, Bio1_000350, Bio1_000839, Bio1_001328, HMS1922K06, HMS2096C06, HMS2231E05, HMS3267L11, EBD11190, BS0234, CCG-39185, GA2328, MFCD00077650, AKOS015916532, API0001506, CS-4981, DB07374, SDCCGMLS-0066810.P001, IDI1_000855, KS-0000001J, QTL1_000009, NCGC00025097-02, NCGC00025097-03, NCGC00025097-04, AS-44380, HY-18982, NCI60_041689, AB00513833, B6674, C11281, Anisomycin, Antibiotic for Culture Media Use Only, SR-01000597397-1, SR-01000597397-3, BRD-K91370081-001-04-6, BRD-K91370081-001-17-8, I14-51828, 3, 2-(p-methoxybenzyl)-, 3-acetate, (2S,3R,4R)-, Anisomycin from Streptomyces griseolus, >=98% (HPLC), solid, (2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol 3-Acetate, (2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate, acetic acid [(2R,3S,4S)-4-hydroxy-2-p-anisyl-pyrrolidin-3-yl] ester, [(2R,3S,4S)-2-[(4-methoxyphenyl)methyl]-4-oxidanyl-pyrrolidin-3-yl] ethanoate, 3, 2-[(4-methoxyphenyl)methyl]-, 3-acetate, [2S-(2.alpha.,3.alpha.,4.beta.)]-, 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, 3-acetate, (2S,3R,4R)- (8CI), acetic acid [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]-3-pyrrolidinyl] ester, 11023-48-6, 2322-08-9

ID: 2711

chemical graph of compound 2711



InChIKey: YKRAQIAZPKGEIC-JYRVWZFOSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)/C(=C\C3=CC(=C(C=C3)OC)OC)/CO2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6857791
synonyms found at PubChem are:
SAPPANONE A TRIMETHYL ETHER, AC1OAH7H, Spectrum5_000493, BSPBio_003362, SPECTRUM1600365, CHEMBL1606022, SCHEMBL14479888, CCG-39515, SDCCGMLS-0066899.P001, NCGC00095763-01, NCGC00095763-02, SR-05000002585, SR-05000002585-1, BRD-K03557653-001-01-9, (3Z)-3-[(3,4-dimethoxyphenyl)methylidene]-7-methoxychromen-4-one

ID: 2712

chemical graph of compound 2712



InChIKey: YKYOQIXTECBVBB-AWEZNQCLSA-N
SMILES: CCOC(=O)C1=C2[C@@H]3CCCN3C(=O)C4=C(N2C=N1)C=CC(=C4)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5311203
synonyms found at PubChem are:
L-655,708, L-655708, 130477-52-0, CHEMBL52030, L 655708, NCGC00025115-02, Ethyl (S)-11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylate, L655708, Lopac0_000700, SCHEMBL5533646, MolPort-003-983-605, YKYOQIXTECBVBB-AWEZNQCLSA-N, HMS3262K21, ZINC2584032, Tox21_500700, BDBM50067424, BN0287, MFCD02684528, AKOS024456530, API0007742, CCG-204785, CS-4943, FG-8094, LP00700, NCGC00025115-03, NCGC00025115-04, NCGC00261385-01, HY-14426, KB-78047, EU-0100700, L 9787, L-655,708, >=98% (HPLC), powder, SR-01000075970, SR-01000597405, J-005812, SR-01000075970-1, SR-01000597405-1, BRD-K13474508-001-01-2, (S)-9-Methoxy-7-oxo-3b,4,5,6-tetrahydro-7H-2,6a,11b-triaza-benzo[g]cyclopenta[e]azulene-3-carboxylic acid ethyl ester, 11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, ethyl ester, 9-Methoxy-7-oxo-3b,4,5,6-tetrahydro-7H-2,6a,11b-triaza-benzo[g]cyclopenta[e]azulene-3-carboxylic acid ethyl ester(MSD), Ethyl(S)-11,12,13,13a-tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrro-lo[2,1-c][1,4]-benzodiazepine-1-carboxylate

ID: 2713

chemical graph of compound 2713



InChIKey: YLEARPUNMCCKMP-DOFZRALJSA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5283389
synonyms found at PubChem are:
N-arachidonylglycine, N-arachidonoylglycine, N-arachidonoyl glycine, NAGly, arachidonoyl glycine, 179113-91-8, N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycine, CHEMBL161343, CHEBI:58961, NCGC00015042-03, DSSTox_CID_25124, DSSTox_RID_80688, DSSTox_GSID_45124, C22H35NO3, 2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]amino]acetic acid, CAS-179113-91-8, SR-01000076205, N-(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)glycine, N-[1-Oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]glycine, arachidonoylglycine, N-Arachidonyl Glycine, N-arachidonyl-L-glycine, Lopac-A-1977, D01ZHW, AC1NR26D, Lopac0_000074, BSPBio_001444, SCHEMBL158050, BML2-C05, GTPL3635, DTXSID5045124, MolPort-003-940-077, YLEARPUNMCCKMP-DOFZRALJSA-N, HMS1361I06, HMS1791I06, HMS1989I06, HMS3402I06, HMS3649B11, ZINC4467867, Tox21_110070, 1909AH, BDBM50056486, FA-029, LMFA08020003, NSC746569, AKOS024456602, Tox21_110070_1, CCG-204169, LP00074, NSC-746569, IDI1_033914, NCGC00015042-01, NCGC00015042-02, NCGC00015042-04, NCGC00015042-05, NCGC00015042-06, NCGC00015042-07, NCGC00015042-08, NCGC00015042-09, NCGC00015042-10, NCGC00015042-11, NCGC00093582-01, NCGC00093582-04, NCGC00093582-05, NCGC00093582-06, NCGC00093582-07, NCGC00093582-08, NCGC00093582-09, ACM179113918, B6742, EU-0100074, A 1977, J-011429, SR-01000076205-1, SR-01000076205-5, BRD-K51557114-001-02-1, ((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic acid, N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]glycine, ((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic acid, Glycine,N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]-

ID: 2714

chemical graph of compound 2714



InChIKey: YLFMCMWKHSDUCT-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4552
synonyms found at PubChem are:
153587-01-0, NS-1619, NS 1619, 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one, NS1619, CHEMBL384903, 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one, CHEBI:34879, YLFMCMWKHSDUCT-UHFFFAOYSA-N, 1-(2'-Hydroxy-5'-trifluoromethylphenyl)-5-trifluoromethyl-2(3H)-benzimidazolone, 1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2h-benzimidazol-2-one, 3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one, 2H-Benzimidazol-2-one,1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-, ACMC-20agb2, NS 1619, powder, Lopac-N-170, AC1Q4JIU, D09BVL, AC1L1IF4, Lopac0_000892, BSPBio_001425, KBioGR_000145, KBioSS_000145, MLS002172485, GTPL4272, SCHEMBL2820871, BCBcMAP01_000241, CTK4C7907, KBio2_000145, KBio2_002713, KBio2_005281, KBio3_000289, KBio3_000290, DTXSID80165363, MolPort-003-958-929, Bio2_000145, Bio2_000625, HMS1361H07, HMS1791H07, HMS1989H07, HMS2233C07, HMS3262D06, HMS3374I04, HMS3402H07, BCP23926, ZINC9225331, Tox21_500892, ANW-72060, BDBM50347497, KC-127, MFCD00928190, AKOS016007330, API0008317, CCG-204974, CS-3613, LP00892, TRA0006161, IDI1_033895, KS-0000001L, NCGC00015720-01, NCGC00015720-02, NCGC00015720-03, NCGC00015720-04, NCGC00015720-05, NCGC00015720-06, NCGC00015720-07, NCGC00094210-01, NCGC00094210-02, NCGC00094210-03, NCGC00094210-04, NCGC00261577-01, 2H-Benzimidazol-2-one, 1,3-dihydro-1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-, AJ-59395, AK-57021, HY-12496, KB-08405, SC-89069, SMR001254108, AX8016190, RT-014760, B7502, EU-0100892, FT-0643507, X6428, C13833, C-20935, SR-01000075337, J-009032, SR-01000075337-1, BRD-K54210043-001-02-0, 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one, 5-trifluoromethyl-2,3-dihydro-1-(5-trifluoromethyl-2-hydroxyphenyl)-1H-2-oxo-benzimidazole, 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imid azol-2(3H)-one, 1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

ID: 2715

chemical graph of compound 2715



InChIKey: YLKRUSPZOTYMAT-UHFFFAOYSA-N
SMILES: C1=C(C(=CC(=C1O)O)O)CC(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 107794
synonyms found at PubChem are:
6-Hydroxy-DL-DOPA, 6-Hydroxydopa, 6-Ohdopa, 2,4,5-Trihydroxyphenylalanine, 2,5-Dihydroxytyrosine, 3,4,6-Topa, 3,4,6-Trihydroxyphenylalanine, 21373-30-8, 23358-64-7, 2-amino-3-(2,4,5-trihydroxyphenyl)propanoic acid, 2,5-Dihydroxy-DL-tyrosine, MLS002153447, CHEMBL109037, CHEBI:20725, 2,4,5-Trihydroxy-DL-phenylalanine, SMR000326920, W-201873, SR-01000075906, DL-6-Hydroxydopa, 6-Hydroxy-DOPA, 2,4,5-Trihydroxyphenyl-D,L-alanine, Tyrosine,2,5-dihydroxy-, AC1L32RF, AC1Q5S4E, Tyrosine, 2,5-dihydroxy-, Lopac0_000633, SCHEMBL503251, CTK4E6601, MolPort-003-895-946, HMS3261P08, Tox21_500633, BDBM50436204, AKOS003382703, AKOS022145815, BRS0000296, CCG-204721, LP00633, MCULE-2477170525, VZ22370, NCGC00015503-02, NCGC00015503-03, NCGC00015503-04, NCGC00015503-05, NCGC00015503-06, NCGC00094000-01, NCGC00094000-02, NCGC00261318-01, EU-0100633, FT-0638316, 6-Hydroxy-DL-DOPA, >=98% (TLC), powder, H 2380, A816687, C-11226, J-015084, SR-01000075906-1, SR-01000075906-7, SR-01000075906-8, 2-azanyl-3-[2,4,5-tris(oxidanyl)phenyl]propanoic acid, ( inverted exclamation markA)-2,4,5-Trihydroxyphenylalanine;

ID: 2716

chemical graph of compound 2716



InChIKey: YLOYKYXNDHOHHT-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1C(=O)OC2=C(C(=C(C(=C2)C)C(=O)OC)O)C)O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 68066
synonyms found at PubChem are:
Atranorin, 479-20-9, Atranorine, Parmelin, Usnarin, Antranoric acid, Atranoric acid, Parmelin acid, Usnarin acid, UNII-450U2VJ2VG, NSC 249980, NSC 685591, EINECS 207-527-7, NSC-685591, 3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate, 450U2VJ2VG, CHEMBL173395, NSC685591, Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester, Benzoic acid,3-formyl-2,4-dihydroxy-6-methyl-,3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester, Benzoic acid,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester, Isophthalaldehydic acid,4-dihydroxy-6-methyl-, 4-ester with methyl 3,6-dimethyl-.beta.-resorcylate, Spectrum_000143, SpecPlus_000239, Spectrum2_001749, Spectrum3_001716, Spectrum4_001700, Spectrum5_000380, AC1L28YN, AC1Q60PP, BSPBio_003332, KBioGR_002000, KBioSS_000623, SPECTRUM200034, 3-formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester, DivK1c_006335, SPBio_001858, SCHEMBL1370191, CTK4J0470, KBio1_001279, KBio2_000623, KBio2_003191, KBio2_005759, KBio3_002552, DTXSID10197319, MolPort-003-665-750, YLOYKYXNDHOHHT-UHFFFAOYSA-N, ZINC608186, NSC87512, BDBM50056919, CCG-38801, NSC-87512, NSC249980, AKOS024319117, API0001563, MCULE-8680934648, NSC-249980, SDCCGMLS-0066426.P001, NCGC00095465-01, NCGC00095465-02, LS-37485, SC-19530, ZB014597, FT-0769622, W2047, C-57468, SR-05000002629, SR-05000002629-1, (3-hydroxy-4-methoxycarbonyl-2,5-dimethyl-phenyl) 3-formyl-2,4-dihydroxy-6-methyl-benzoate, (3-hydroxy-4-methoxycarbonyl-2,5-dimethylphenyl) 3-formyl-2,4-dihydroxy-6-methylbenzoate, 3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate #, Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester (9CI), Isophthalaldehydic acid, 2,4-dihydroxy-6-methyl-, 4-ester with methyl 3,6-dimethyl-.beta.-resorcylate, Isophthalaldehydic acid, 2,4-dihydroxy-6-methyl-, 4-ester with methyl 3,6-dimethyl-beta-resorcylate, Isophthalaldehydic acid, 2,4-dihydroxy-6-methyl-, 4-ester with methyl 3,6-dimethyl-beta-resorcylate (8CI), methyl 1-(3-formyl-2,4-dihydroxy-6-methylphenylcarbonyloxy)-3-hydroxy-2,5-dimethyl-4-benzenecarboxylate

ID: 2717

chemical graph of compound 2717



InChIKey: YLXDSYKOBKBWJQ-LBPRGKRZSA-N
SMILES: CCC(=O)NCC[C@@H]1CCC2=C1C3=C(C=C2)OCC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 208902
synonyms found at PubChem are:
Ramelteon, 196597-26-9, Rozerem, TAK-375, Ramelteon [USAN], Rozerem (TN), UNII-901AS54I69, (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, CHEMBL1218, Ramelteon (JAN/USAN/INN), (S)-N-(2-(1,6,7,8-tetrahydro-2H-indeno-(5,4)furan-8-yl)ethyl)propionamide, N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e][1]benzofuran-8-yl]ethyl]propanamide, 901AS54I69, (S)-N-(2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)propionamide, n-{2-[(8s)-1,6,7,8-tetrahydro-2h-indeno[5,4-b]fur-8-yl]ethyl}propanamid, (-)-N-(2-(((8S)-1,6,7,8-Tetrahydro-2H-indeno(5,4-b)furan-8-yl)ethyl)propanamide, (S)-N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionamide, N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e]benzofuran-8-yl]ethyl]propanamide, N-{2-[(8S)-1H,2H,6H,7H,8H-INDENO[5,4-B]FURAN-8-YL]ETHYL}PROPANAMIDE, Propanamide, N-(2-((8S)-1,6,7,8-tetrahydro-2H-indeno(5,4-b)furan-8-yl)ethyl)-, SMR002544684, SR-05000001957, HSDB 7787, (S)-N-(2-[1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl)propionamide, (S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, Ramelteon [USAN:INN:BAN:JAN], PubChem19120, Ramelteon, TAK-375, AC1L4LKM, AC1Q5OQL, Ramelteon (TAK-375), D0U0KW, SCHEMBL29237, BSPBio_002318, MLS003915619, MLS006010029, TAK-375SL, SPECTRUM1505817, GTPL1356, TAK375, Rozerem, TAK-375, Ramelteon, CTK8E7499, CHEBI:109549, MolPort-003-666-751, YLXDSYKOBKBWJQ-LBPRGKRZSA-N, HMS1922H18, HMS2093F12, ACT06830, AOB87305, HY-A0014, KS-00000XI5, ZINC3960338, ABP001059, BDBM50118470, CR0011, s1259, Ramelteon 1.0 mg/ml in Acetonitrile, AKOS015895741, AC-5275, AM84670, AN-3478, API0000796, CCG-213557, CS-0382, DB00980, PB27872, RL02472, NCGC00178707-03, AJ-47537, AS-15740, BC225579, Q499, SBI-0206874.P001, AB0017627, AB1008454, LS-186569, LS-187367, RT-015379, FT-0655799, ST24049116, D02689, Q-4378, AB01274760-01, AB01274760_02, AB01274760_03, 597R269, I06-1429, J-502508, SR-05000001957-1, SR-05000001957-3, BRD-K28761891-001-01-0, BRD-K28761891-001-04-4, Z2037281108, N-[-[(8S)-1,6,7,8-TETRAHYDRO-2H-INDENO[5,4-B]FURAN-8-YL]ETHYL]PROPANAMIDE, N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-indacen-8-yl)-ethyl]-propionamide(S)-(-)-22b, N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e][1]benzoxol-8-yl]ethyl]propanamide, Ramelteon solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material

ID: 2718

chemical graph of compound 2718



InChIKey: YMBCJWGVCUEGHA-UHFFFAOYSA-M
SMILES: CC[N+](CC)(CC)CC.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5946
synonyms found at PubChem are:
TETRAETHYLAMMONIUM CHLORIDE, 56-34-8, Tetraethyl ammonium chloride, Etamon chloride, Tea chloride, TEAC, N,N,N-Triethylethanaminium chloride, Ethanaminium, N,N,N-triethyl-, chloride, tetraethylammoniumchloride, tetraethyl-ammonium chloride, EINECS 200-267-5, UNII-8B82Z83XNN, Et4NCl, Ammonium, tetraethyl-, chloride, CHEBI:78161, N,N,N-Triethylethanaminium, NCGC00094439-01, 8B82Z83XNN, MFCD00011828, AK164439, N,N,N,N-TETRAETHYLAMMONIUM CHLORIDE, DSSTox_CID_21137, DSSTox_RID_79633, DSSTox_GSID_41137, Ethanaminium, N,N,N-triethyl-, chloride (1:1), 66-40-0 (Parent), t.e.a. chloride, CAS-56-34-8, C8H20N.Cl, ACMC-209lry, tetraethylazanium chloride, AC1Q1RXV, tetraethylammonium-chloride, tetra-ethylammonium chloride, AC1L1LH6, Lopac0_001185, SCHEMBL49847, tetra-ethyl ammonium chloride, KSC269G9N, MLS001056762, Tetra ethyl Ammonium Chloride, CHEMBL434435, DTXSID6041137, CTK1G9396, KS-00000EBM, MolPort-003-939-285, YMBCJWGVCUEGHA-UHFFFAOYSA-M, HMS2233B21, HMS3263N11, HMS3372P01, ACT05650, Tox21_111281, Tox21_302129, Tox21_501185, ANW-32492, AKOS017345097, Tox21_111281_1, CCG-222489, JC10005, LP01185, MCULE-7118179492, RP22850, RTR-019791, TRA0077711, NCGC00016008-04, NCGC00255648-01, NCGC00261870-01, AN-24437, AS-11727, LS-19031, SC-25801, SMR000326719, DB-050378, TR-019791, B7262, EU-0101185, FT-0631248, Tetraethylammonium chloride, >=98.0% (AT), T 2265, 42321-EP2311808A1, 42321-EP2311829A1, 60554-EP2286811A1, 60554-EP2308857A1, 60554-EP2308873A1, Tetraethylammonium chloride, >=98% (titration), SR-01000075347, J-524852, SR-01000075347-1, Tetraethylammonium chloride, Vetec(TM) reagent grade, 98%, Tetraethylammonium chloride, for electrochemical analysis, >=99.0%, Tetraethylammonium chloride, BioUltra, for molecular biology, >=99.0% (AT)

ID: 2719

chemical graph of compound 2719



InChIKey: YMBXTVYHTMGZDW-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3965
synonyms found at PubChem are:
Loxoprofen, 68767-14-6, 2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid, Loxoprofene, Loxoprofeno, Koloxo, sodium loxoprofen, Loxoprofenum, Loxoprofen sodium, Loxoprofen [INN], Loxoprofene [French], Loxoprofenum [Latin], Loxoprofeno [Spanish], 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid, yl]-propionic acid, 2-[4-(2-Oxo-cyclopentylmethyl)-phen, 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid, CHEMBL19299, Loxoprofen sodium hydrate, CHEBI:76172, CS-600, YMBXTVYHTMGZDW-UHFFFAOYSA-N, Loxoprofen (INN), Loxonin, Oxeno, NCGC00015594-02, CS 600, DSSTox_CID_25164, DSSTox_RID_80714, DSSTox_GSID_45164, (+-)-p-((2-Oxocyclopentyl)methyl)hydratropic acid, Q-201324, Q-300011, 2-(4-((2-oxocyclopentyl)methyl)phenyl)propionic acid, CAS-68767-14-6, Sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate, 2-OCPPP, 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid, Loxoprofen, solid, Lopac0_000677, SCHEMBL24423, C15H17NaO3, AC1L1H42, DTXSID1045164, CTK8B4007, MolPort-005-933-136, alpha-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, HMS3262G15, Loxoprofen (low-melting polymorph), BCP10971, EBD24378, HY-B0578, KS-00000GI6, Loxoprofen (high-melting polymorph), Tox21_110178, Tox21_500677, ANW-43655, BDBM50140320, MFCD00864331, s4682, AKOS015906359, Tox21_110178_1, AC-8108, AN-8339, API0000637, AT-7141, CCG-204763, CS-2760, DB09212, GS-3193, LP00677, NCGC00015594-03, NCGC00015594-04, NCGC00094037-01, NCGC00094037-02, NCGC00261362-01, NCGC00263577-01, AC-15776, AK-72809, BC202797, BR-72809, CC-30044, H883, SC-46851, AB0012364, AX8136713, KB-222031, LS-176693, ST2409307, TR-022937, 4CH-007428, EU-0100677, FT-0641207, L0244, D08149, L 0664, M-9376, (+-)-((2-oxocyclopentyl)methyl)hydratropic acid, 767L146, A836244, C-15016, SR-01000075955, SR-01000075955-1, 2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic acid, 2-[4-(2-oxocyclopentan-1-ylmethyl)phenyl]propionic acid, 2-[4-(2-Oxocyclopentan-1-ylmethyl)phenyl]-propionic Acid, 2-[4-[(2-oxidanylidenecyclopentyl)methyl]phenyl]propanoic acid, Benzeneacetic acid, .alpha.-methyl-4-[(2-oxocyclopentyl)methyl]-

ID: 2720

chemical graph of compound 2720



InChIKey: YMKDRGPMQRFJGP-UHFFFAOYSA-M
SMILES: CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 31239
synonyms found at PubChem are:
cetylpyridinium chloride, 123-03-5, 1-Hexadecylpyridinium chloride, hexadecylpyridinium chloride, Pristacin, 1-hexadecylpyridin-1-ium chloride, Cetamium, Dobendan, Pyrisept, Tserigel, Aktivex, Biosept, Cepacol, Ceprim, Ceepryn chloride, Cepacol chloride, Quaternario CPC, Acetoquat CPC, Intexsan CPC, Swabettes Hoechst, Ammonyx CPC, N-Hexadecylpyridinium chloride, Cetyl pyridinium chloride, N-Cetylpyridinium chloride, 1-Cetylpyridinium chloride, Medilave, Merocet, Ceeprin chloride, hexadecyl pyridinium chloride, Pyridinium, 1-hexadecyl-, chloride, 1-Palmitylpyridinium chloride, Cetylpyridini chloridum, Caswell No. 166A, Cloruro de cetilpiridinio, Chlorure de cetylpyridinium, UNII-6BR7T22E2S, Cetylpyridinii chloridum, HSDB 38, Cetilpiridinio cloruro [DCIT], CETYLPYRIDINIUM CHLORIDE ANHYDROUS, EINECS 204-593-9, Cetylpyridinii chloridum [INN-Latin], NSC 14864, EPA Pesticide Chemical Code 069160, Cloruro de cetilpiridinio [INN-Spanish], Chlorure de cetylpyridinium [INN-French], AI3-15070, 6BR7T22E2S, CETYL PYRIDINIUM CHLORINE, CHEBI:32915, Pyridinium, 1-hexadecyl-, chloride (1:1), C21H38N, Cetilpiridinio cloruro, CPC, cerigel, Cetylpyridinium chloride [INN], NB 002, Cetyl-pyridinium chloride, Hexadecylpyridiniumchloride, hexadecylpyridine, chloride, AC1L1L7M, AC1Q1RR6, C21H38ClN, SCHEMBL4763, DSSTox_CID_21761, DSSTox_RID_79838, DSSTox_GSID_41761, ARONIS24387, CHEMBL34833, SPECTRUM1500169, 1-Hexadecyl-Pyridinium Chloride, DTXSID6041761, CTK0H6090, HMS501B08, MolPort-001-789-391, YMKDRGPMQRFJGP-UHFFFAOYSA-M, HMS1920M13, HMS2091A20, HMS3652F05, Pharmakon1600-01500169, 1-hexadecylpyridine chloride hydrate, ACT02661, CETYLPYRIDINIUM CHLORIDE H2O, KS-00000FW6, NSC14864, Cetylpyridinium Chloride (anhydrous), Tox21_301296, 1-Cetylpyridinium chloride 1-hydrate, CCG-39719, NSC-14864, NSC756673, s4172, SBB080799, AKOS005267197, KS-5309, MCULE-9273804888, NE10697, NSC-756673, RP17926, WLN: T6KJ A16 & Q & G, NCGC00094618-01, NCGC00094618-02, NCGC00257543-01, AN-22898, CAS-123-03-5, SC-13698, U303, DB-041704, LS-132591, TL8003812, FT-0082393, FT-0602586, 97702-EP2277879A1, 97702-EP2295426A1, 97702-EP2295427A1, 97702-EP2305662A1, A832584, SR-05000001582, I02-0514, SR-05000001582-1, W-105282, Acetoquat CPCPyriseptEXADECYL-PYRIDINIUM, CHLORIDE, 136499-13-3, 27841-61-8, 50958-35-5, 951742-58-8, SCHEMBL5522396

ID: 2721

chemical graph of compound 2721



InChIKey: YMTINGFKWWXKFG-UHFFFAOYSA-N
SMILES: CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3339
synonyms found at PubChem are:
fenofibrate, 49562-28-9, Procetofen, Lipanthyl, Lipantil, Antara, Tricor, Fenobrate, Lipidil, Secalip, Fenoglide, Finofibrate, Lipoclar, Lipofene, Proctofene, Triglide, Fenogal, Lipirex, Lipofen, Sedufen, Elasterin, Fenotard, Protolipan, Ankebin, Lipidex, Lipifen, Liposit, Lipsin, Nolipax, Elasterate, Procetofene, Luxacor, Fenofibratum, Fenofibrato, Lofibra, Fenofibratum [INN-Latin], Fenofibrato [INN-Spanish], Lipantil (TN), Tricor (TN), Phenofibrate, Fibricor, Supralip, LF-178, Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate, Antara (micronized), TRICOR (MICRONIZED), propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate, Fenomax, Pharmavit, Fulcro, FENOFIBRATE (MICRONIZED), Lipidil Micro, Lipidil Supra, Fenofibrate [INN:BAN], CIP-Fenofibrate, Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate, LCP-FenoChol, Fenofibrate IDD-P, LCP-Feno, Triglide (TN), C20H21ClO4, Lipofen (TN), 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, NSC 281319, UNII-U202363UOS, Antara (TN), CCRIS 7282, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate, FNF, Fenofibrate (JAN/INN), EINECS 256-376-3, LF 178, CHEMBL672, BRN 2062462, Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester, MLS000028515, CHEBI:5001, isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate, GRS-027, YMTINGFKWWXKFG-UHFFFAOYSA-N, U202363UOS, Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester, NCGC00015437-10, Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate, SMR000058299, CAS-49562-28-9, 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester, DSSTox_CID_9874, F 6020, DSSTox_RID_78828, DSSTox_GSID_29874, Q-201111, durafenat, Fenofanton, Controlip, Fenobeta, isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate, Liparison, Apo Fenofibrate, Apo-Fenofibrate, Gen Fenofibrate, Gen-Fenofibrate, Nu Fenofibrate, Nu-Fenofibrate, Fenofibrat AbZ, Fenofibrat FPh, 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester, Fenofibrat AL, Fenofibrat Hexal, Fenofibrat Stada, Fenofibrate MSD, Lipidil Ter, Lipidil-Ter, Novo Fenofibrate, Novo-Fenofibrate, Fenofibrat AZU, MTW Fenofibrat, MTW-Fenofibrat, 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester, Fenofibrate Debat, Apo Feno Micro, Apo-Feno-Micro, AZU, Fenofibrat, fenofibrat von ct, Fenofibrat Heumann, Hexal, Fenofibrat, Stada, Fenofibrat, Debat, Fenofibrate, Heumann, Fenofibrat, Fenofibrat ratiopharm, Fenofibrat-ratiopharm, PMS Fenofibrate Micro, PMS-Fenofibrate Micro, SR-01000000091, Antara Micronized Procetofen, clorofibrate, Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate, Procetoken, Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate, Micronized Procetofen, Antara, Procetofen, Antara Micronized, fenofibrate;, methylethyl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate, HSDB 7736, Fenofibrate,(S), METHYLETHYL 2-(4-[(4-CHLOROPHENYL)CARBONYL]PHENOXY)-2-METHYLPROPANOATE, LF178, Lipanthyl (TN), Fenofibrate [USAN:USP:INN:BAN], Prestwick_217, Fenogal (TN), Lipidil (TN), Lofibra (TN), FENOFIBRITE, Fenocor-67 (TN), PubChem17489, Spectrum_001250, Opera_ID_328, AbZ Brand of Procetofen, Procetofen Reliant Brand, MTW Brand of Procetofen, AC1L1FPK, Anto Brand of Procetofen, Gate Brand of Procetofen, Prestwick0_000275, Prestwick1_000275, Prestwick2_000275, Prestwick3_000275, Spectrum2_001390, Spectrum3_001431, Spectrum4_000413, Spectrum5_001479, Lopac-F-6020, Aliud Brand of Procetofen, Hexal Brand of Procetofen, Knoll Brand of Procetofen, Abbott Brand of Procetofen, Apotex Brand of Procetofen, D07XGR, EC 256-376-3, Heumann Brand of Procetofen, Reliant Brand of Procetofen, SCHEMBL4670, Bouchara Brand of Procetofen, Fournier Brand of Procetofen, Genpharm Brand of Procetofen, Novartis Brand of Procetofen, Lopac0_000486, Q Pharm Brand of Procetofen, Q-Pharm Brand of Procetofen, betapharm Brand of Procetofen, BSPBio_000150, BSPBio_003162, KBioGR_000706, KBioSS_001730, Azupharma Brand of Procetofen, MLS001148191, MLS002548878, Novopharm Brand of Procetofen, Nu Pharm Brand of Procetofen, Nu-Pharm Brand of Procetofen, BIDD:GT0574, DivK1c_000557, ratiopharm Brand of Procetofen, SPECTRUM1501010, SPBio_001380, SPBio_002369, Stadapharm Brand of Procetofen, Fenofibrate, >=99%, powder, Merck dura Brand of Procetofen, BPBio1_000166, Fenofibrate (Tricor, Trilipix), GTPL7186, GNR Pharma Brand of Procetofen, GNR-Pharma Brand of Procetofen, DTXSID2029874, Lichtenstein Brand of Procetofen, United Drug Brand of Procetofen, CTK8B3039, HMS501L19, KBio1_000557, KBio2_001730, KBio2_004298, KBio2_006866, KBio3_002382, Pharmascience Brand of Procetofen, MolPort-002-887-051, NINDS_000557, HMS1568H12, HMS1921B17, HMS2090G20, HMS2092B05, HMS2095H12, HMS2231B14, HMS3259K03, HMS3261B13, HMS3369M13, HMS3649D20, HMS3655K12, HMS3712H12, Pharmakon1600-01501010, ZINC584092, ALBB-028958, BCP21243, ct Arzneimittel Brand of Procetofen, ct-Arzneimittel Brand of Procetofen, EBD45918, Schering Plough Brand of Procetofen, Schering-Plough Brand of Procetofen, ZX-AN079771, Tox21_110147, Tox21_300151, Tox21_500486, ANW-41658, BDBM50085042, BG0483, CCG-38996, GP4850, MFCD00133314, NSC281319, NSC757822, s1794, SBB037926, AKOS005107777, Tox21_110147_1, AB03716, AC-4227, AN-9654, API0003184, API0025994, API0026002, API0026009, CS-0892, DB01039, LP00486, MCULE-9460650238, MS-2223, NC00452, NSC-281319, NSC-757822, IDI1_000557, NCGC00015437-01, NCGC00015437-02, NCGC00015437-03, NCGC00015437-04, NCGC00015437-05, NCGC00015437-06, NCGC00015437-07, NCGC00015437-08, NCGC00015437-09, NCGC00015437-11, NCGC00015437-12, NCGC00015437-13, NCGC00015437-14, NCGC00015437-16, NCGC00015437-17, NCGC00021475-03, NCGC00021475-04, NCGC00021475-05, NCGC00021475-06, NCGC00021475-07, NCGC00021475-08, NCGC00253945-01, NCGC00261171-01, AJ-23609, BC202978, CC-28385, CPD000058299, FENOFIBRATE (MICRONIZED) (fenofibrate, Fenofibrate, analytical reference material, HY-17356, SAM002264613, ST085313, ZB014484, SBI-0050470.P003, AB0012237, AB2000298, AX8021009, LS-121256, TC-130403, TL8003296, AB00052196, EU-0100486, F0674, FT-0626400, FT-0654669, KS-00000655, C07586, D00565, J10318, K-9221, 28073-EP2272825A2, 28073-EP2272841A1, 28073-EP2277565A2, 28073-EP2277566A2, 28073-EP2277567A1, 28073-EP2277568A2, 28073-EP2277569A2, 28073-EP2277570A2, 28073-EP2287163A1, 28073-EP2287165A2, 28073-EP2287166A2, 28073-EP2292280A1, 28073-EP2292620A2, 28073-EP2295409A1, 28073-EP2298742A1, 28073-EP2298776A1, 28073-EP2301923A1, 28073-EP2301936A1, 28073-EP2305678A1, 28073-EP2314588A1, AB00052196-15, AB00052196-16, AB00052196_17, AB00052196_18, 562F289, A827746, C-20905, I06-0048, SR-01000000091-2, SR-01000000091-5, SR-01000000091-6, SR-01000000091-8, BRD-K50388907-001-05-6, BRD-K50388907-001-18-9, BRD-K50388907-001-20-5, SR-01000000091-16, Z2768724415, Fenofibrate, European Pharmacopoeia (EP) Reference Standard, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoicacidisopropylester, 2-1-methylethyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate, Fenofibrate, United States Pharmacopeia (USP) Reference Standard, Isopropyl (4''-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid,1-methylethylester, 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methyl-ethyl ester, Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material, propan-2-yl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate, propan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate, 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYL-PROPANOIC ACID 1-METHYLETHYL ESTER, 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid propan-2-yl ester, PROPAN-2-YL-2-(4-[(4-CHLOROPHENYL)CARBONYL]PHENOXY)-2-METHYLPROPANOATE

ID: 2722

chemical graph of compound 2722



InChIKey: YMVGDYYRAKPUNZ-UHFFFAOYSA-N
SMILES: C(C1=CC=CS1)1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "F Cateni" "N Pedemonte" "LJ Galietta" "M Giampieri" "M Mazzei" "MT Mazzei" "M Zacchigna"


CID is 619188
synonyms found at PubChem are:
3,5-dimethyl 2,6-dimethyl-4-(thiophen-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate, 162229-14-3, AC1LDIMI, BAS 01152212, Oprea1_161481, Oprea1_481779, AC1Q426N, CHEMBL593872, IFLab1_001827, MolPort-000-419-206, YMVGDYYRAKPUNZ-UHFFFAOYSA-N, HMS1417D01, CCG-17230, STK861970, ZINC19418567, AKOS000531409, MCULE-8156977914, SR-01000443548, SR-01000443548-1, Z57457542, dimethyl 2,6-dimethyl-4-(2-thienyl)-1,4-dihydropyridine-3,5-dicarboxylate, 2,6-DIMETHYL-4-THIOPHEN-2-YL-1,4-2H-PYRIDINE-3,5-DICARBOXYLIC ACID DI-ME ESTER, 4-(2-Thienyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester, dimethyl 2,6-dimethyl-4-(thiophen-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate, dimethyl 2,6-dimethyl-4-thiophen-2-yl-1,4-dihydropyridine-3,5-dicarboxylate

ID: 2723

chemical graph of compound 2723



InChIKey: YNAGNECWEKMWRM-UHFFFAOYSA-M
SMILES: CCCCCC(CCCC(=O)[O-])O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9794325
synonyms found at PubChem are:
5-hydroxydecanoic acid sodium, Sodium 5-hydroxydecanoate, 5-Hydroxydecanoic acid sodium salt, 5-hydroxydecanoate sodium salt, 71186-53-3, potassium 5-hydroxydecanoate, C10H19NaO3, SCHEMBL1320607, CHEMBL1255658, HMS1361O06, HMS3261N18, Tox21_500628, MFCD00153808, AKOS027257463, API0015022, CCG-221932, LP00628, NCGC00016152-02, NCGC00093996-01, NCGC00261313-01, EU-0100628, H-135, X6848, 5-Hydroxydecanoic acid sodium salt, >=97% (HPLC)

ID: 2724

chemical graph of compound 2724



InChIKey: YNDXUCZADRHECN-JNQJZLCISA-N
SMILES: C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6436
synonyms found at PubChem are:
TRIAMCINOLONE ACETONIDE, 76-25-5, Azmacort, Aristoderm, Aristogel, Kenalone, Solodelf, Tramacin, Triaceton, Tricinolon, Flutone, Kenalog, Rineton, Triam-Injekt, Adcortyl A, Nasacort AQ, Omcilon A, Coupe-A, Volon A, Aristocort acetonide, Kenalog 40, Tricort-40, Triamcinolone 16,17-acetonide, Acetospan, Oracort, Oralone, Triacort, Triatex, Triderm, Zilretta, Flutex, AllerNaze, Triamcincolone acetonide, Volon A 40, Kenalog-H, Nasacort HFA, Triamonide 40, Triamcinolone (acetonide), Kenalog in Orabase, Kenalog-10, Kenalog-40, Vetalog (Veterinary), Nasacort, Vetalog, Triamsinolone acetonide, Kenacort-A, TAC-3, Triacet, Trymex, Panolog Ointment (Veterinary), UNII-F446C597KA, Aristocort A, CCRIS 5231, Tri-Nasal, Triamcinolone Acetonide in Absorbase, EINECS 200-948-7, 9alpha-Fluoro-16alpha-17alpha-isopropyledenedioxyprednisolone, NSC 21916, BRN 0060069, MLS000028538, CHEBI:71418, 9alpha-Fluoro-16-hydroxyprednisolone acetonide, 9-alpha-Fluoro-16-hydroxyprednisolone acetonide, F446C597KA, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-, SMR000058335, 9-alpha-Fluoro-16-alpha-17-alpha-isopropyledenedioxyprednisolone, 9-alpha-Fluoro-16-alpha-hydroxyprednisolone 16-alpha,17-alpha-acetonide, DSSTox_CID_1371, 9-alpha-Fluoro-16-alpha-17-alpha-isopropylidenedioxy-delta-1-hydrocortisone, 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione, DSSTox_RID_76115, DSSTox_GSID_21371, (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha,17-alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione, 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, Cinonide, Trianex, Triesence, Trivaris, 9alpha-Fluoro-16alpha-hydroxyprednisolone 16alpha,17alpha-acetonide, Kenacort A, 9alpha-fluoro-16alpha-17alpha-isopropylidenedioxy-Delta-1-hydrocortisone, 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide, 9alpha-Fluoro-11beta,21-dihydroxy-16alpha,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione, CAS-76-25-5, (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, MLS002638825, Nasacort Allergy 24 Hour, aristicort, Triamcinolone acetonide [JAN], 9?-Fluoro-11?,21-dihydroxy-16?,17?-isopropylidenedioxypregna-1,4-diene-3,20-dione, FX006, NCGC00023193-04, triamcinoloneacetonide, Asmacort [Common Misspelling of Azmacort], Opera_ID_232, AC1Q2CRE, Triamcinolone acetonide [USP:INN:BAN:JAN], AC1L1MJ3, SCHEMBL4689, CHEMBL1504, 5-19-06-00568 (Beilstein Handbook Reference), fx-006, MLS001148264, MLS002207192, 9.alpha.-Fluoro-16.alpha.-17.alpha.-isopropyledenedioxyprednisolone, GTPL2867, DTXSID6021371, 1,2-d][1,3]dioxol-4-one, 9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone 16.alpha.,17.alpha.-acetonide, MolPort-002-529-154, YNDXUCZADRHECN-JNQJZLCISA-N, HMS2232F22, HMS3259A20, HY-B0636, NSC21916, ZINC3875481, Tox21_110885, Tox21_201795, Tox21_303014, MFCD00056834, NSC-21916, Triamcinolone acetonide (JP17/USP), AKOS015894871, Tox21_110885_1, AC-1239, ACN-043361, CS-2871, KS-5330, LS-1692, NC00591, VZ33964, NCGC00023193-05, NCGC00023193-06, NCGC00256560-01, NCGC00259344-01, AN-15131, AB1010917, Triamcinolone acetonide, analytical standard, S1628, ST24050240, C08183, D00983, J10453, 9.alpha.-Fluoro-16-hydroxyprednisolone acetonide, AB00383012-11, AB00383012_12, 056T834, C-22292, Q-201855, 9.alpha.-Fluoro-11.beta.,4-pregnadiene,3,20-dione, BRD-K53790871-001-08-6, TRIAMCINOLONE ACETONIDE (SEE ALSO TRIAMCINOLONE (124-94-7)), Triamcinolone acetonide, European Pharmacopoeia (EP) Reference Standard, Triamcinolone acetonide, United States Pharmacopeia (USP) Reference Standard, WLN: T F5 E5 B666 GO IO RV AHTTTT&J A1 BF CQ E1 FV1Q H1 H1, 9.alpha.-Fluoro-16.alpha.-17.alpha.-isopropylidenedioxy-.delta.-1-hydrocortisone, 9|A-Fluoro-11|A,21-dihydroxy-16|A,17-isopropylidenedioxy-1,4-pregnadiene-3,20-dione, alpha-Fluoro-11beta,16alpha,17,21-tetra-hydroxypregna-1,4-diene-3,20-dione, Pregna-1,20-dione, 9-fluoro-11.beta.,21-dihydroxy-16.alpha.,17-(isopropylidenedioxy)-, Triamcinolone Acetonide, Pharmaceutical Secondary Standard; Certified Reference Material, (4aS,4bR,5S,6aS,6bR,9aR)-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, (6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-6b-fluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[, 13586-95-3, 138265-06-2, 1TA, 8054-16-8, 911437-91-7, 9A-FLUORO-11B,16A,17A,21-TETRAHYDROXY-1,4-PREGNADIENE-3,20-DIONE 16,17-ACETONIDE, Pregna-1,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11.beta.,16.alpha.)-, Pregna-1,20-dione, 9-fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Pregna-1,20-dione, 9-fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-,cyclic 16,17-acetal with acetone, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (8CI), Triamcinolone acetonide for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 2725

chemical graph of compound 2725



InChIKey: YNEKMCSWRMRXIR-UHFFFAOYSA-N
SMILES: C1C2C(C(C(C1(Cl)Cl)(C2(CCl)C(Cl)Cl)CCl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 58167
synonyms found at PubChem are:
2,2,5-endo,6-exo,8,8,9,10-Octachlorobornane, BORNANE, 2,2,5-endo,6-exo,8,8,9,10-OCTACHLORO-, Camphechlor, Parlar 42b, AC1L1OEZ, 2,2,5-Endo,6-exo,8,9,9,10-octachlorobornane, UNII-9924JQ4D5J, YNEKMCSWRMRXIR-UHFFFAOYSA-N, 9924JQ4D5J, 101053-41-2, LS-45095, 2,2,5,6,8,8,9,10-Octachlorobornane, 2,3,5,5-tetrachloro-4,7-bis(chloromethyl)-7-(dichloromethyl)bicyclo[2.2.1]heptane, 2,2,5,6-Tetrachloro-1,7-bis(chloromethyl)-7-(dichloromethyl)bicyclo[2.2.1]heptane, (5-endo,6-exo,7-syn)-, Bicyclo[2.2.1]heptane, 2,2,5,6-tetrachloro-1,7-bis(chloromethyl)-7-(dichloromethyl)-, (5-endo,6-exo,7-syn)-

ID: 2726

chemical graph of compound 2726



InChIKey: YNNUSGIPVFPVBX-NHCUHLMSSA-N
SMILES: C[C@@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[C@H]3CCCN3C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 26987
synonyms found at PubChem are:
clemastine, Meclastin, Mecloprodin, Clemastina, Clemastinum, 15686-51-8, Meclastine, Clemastinum [INN-Latin], Clemastina [INN-Spanish], Tavegyl, HS-592, HS 592, Clemastine [USAN:BAN], C21H26ClNO, UNII-95QN29S1ID, Tavegil, (+)-(2R)-2-(2-(((R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine, Tavist (*Fumarate*), CHEMBL1626, 95QN29S1ID, CHEBI:3738, 2-(2-(4-Chlor-alpha-methylbenzhydryloxy)ethyl)-1-methylpyrrolidin, (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine, (+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine, (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine, MLS002154260, 2(R)-[2-[(1R)-(4-Chlorophenyl)-1-phenyl-ethoxy]ethyl-1-methylpyrrolidine, (2R)-2-(2-{[(1R)-1-(4-chlorophenyl)-1-phenylethyl]oxy}ethyl)-1-methylpyrrolidine, Tavist (TN), Pyrrolidine, 2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methyl-, (R-(R*,R*))-, NCGC00016710-01, SMR001233520, CAS-14976-57-9, Clemastine [USAN:INN:BAN], 2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine, (R)-2-(2-((R)-1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine, (R)-2-[2-[(R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine, Tavegyl (TN), Tocris-1453, AC1L1CAE, Prestwick0_000306, Prestwick1_000306, Prestwick2_000306, Prestwick3_000306, Spectrum2_000689, Spectrum3_000353, Spectrum4_000955, Spectrum5_001520, Lopac-C-8903, D0C5XC, SCHEMBL4178, BSPBio_000272, BSPBio_002045, KBioGR_001570, BIDD:GT0391, DivK1c_000285, SPBio_000817, SPBio_002491, AC1Q3N52, BPBio1_000300, GTPL6063, DTXSID2022832, BDBM94606, KBio1_000285, KBio3_001265, cid_45479735, NINDS_000285, YNNUSGIPVFPVBX-NHCUHLMSSA-N, HMS2089I22, KUC112480N, ZINC402830, BDBM50253157, DL-247, API0009140, DB00283, IDI1_000285, NCGC00015281-01, NCGC00016710-02, NCGC00025168-01, 63813-90-1, CC-25901, KSC-315-033-, M192, SBI-0052796.P003, LS-137531, FT-0772929, AB00053766-06, AB00053766-07, AB00053766_08, AB00053766_09, 686C518, C-23710, BRD-K30240666-051-05-0, BRD-K30240666-051-08-4, pyrrolidine,2-[2-[1-1-phenylethoxy]ethyl]-1-methyl-, -, (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine, (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine;fumarate, (E)-2-butenedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine, (E)-but-2-enedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine, (E)-but-2-enedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine

ID: 2727

chemical graph of compound 2727



InChIKey: YNPFMWCWRVTGKJ-UHFFFAOYSA-N
SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 68551
synonyms found at PubChem are:
Mianserin hydrochloride, 21535-47-7, Mianserin HCl, Mianserine hydrochloride, Tolvon, Bolvidon, Athymil, Norval, Tolvin, Mianserin (hydrochloride), ORG GB 94, Lerivon, MLS000069681, SMR000058472, GB 94, EINECS 244-426-7, Mianserin hydrochloride [USAN:JAN], 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride, mianserine HCl, 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)-pyrazino(1,2-a)azepine monohydrochloride, 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine hydrochloride, 1,2,3,4,10,14beta-Hexahydro-2-methyldibenzo[c,f]pyryzino[1,2-a]azepine hydrochloride, 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride, Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, monohydrochloride, CHEBI:31843, SR-01000000185, Tetramide (TN), Prestwick_514, Mianserin Hydrocloride, Bolvidon;Norval;Tolvon, (.+-.)-Athymil, Opera_ID_1505, (.+-.)-Norval, ORG GB-94 HCl, AC1L29ZA, AC1Q38XJ, C18H20N2.HCl, cid_68551, MLS001148213, MLS002222220, SCHEMBL340474, SPECTRUM2300292, CHEMBL544428, BDBM31005, CTK4F3129, HY-B0188A, KS-00000ZQX, MolPort-003-666-778, HMS1568C20, Pharmakon1600-02300292, 24219-97-4 (Parent), BCP09259, EBD23593, Mianserin hydrochloride (JAN/USAN), Tox21_500744, AN-730, CCG-39108, MFCD00055072, NSC292267, NSC759590, s1382, AKOS015902308, API0005729, CS-2079, KS-5096, LP00744, NSC-292267, NSC-759590, VA11292, 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride(1:1), NCGC00094086-01, NCGC00094086-02, NCGC00094086-03, NCGC00094086-04, NCGC00261429-01, AC-25005, BC683953, LS-61198, SC-14149, AB0008516, AB2000076, TX-017754, EU-0100744, FT-0628940, M2623, D01358, M 2525, 535M477, SR-01000000185-2, SR-01000000185-4, SR-01000000185-8, W-111733, I14-13356, Mianserin Hydrochloride 1.0 mg/ml in Methanol (as free base), Mianserin hydrochloride, analytical standard, for drug analysis, Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-, Mianserin hydrochloride, European Pharmacopoeia (EP) Reference Standard, 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyryzino[1,2-a]azepine hydrochloride, Mianserin for system suitability, European Pharmacopoeia (EP) Reference Standard, 5-methyl-2,5-diazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8(13),9,11,16,18-hexaene hydrochloride, 78644-54-9, Bolvidon; 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride, AC1LCW5X, AKOS026749945

ID: 2728

chemical graph of compound 2728



InChIKey: YNQQEYBLVYAWNX-WLHGVMLRSA-N
SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=C/C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5282408
synonyms found at PubChem are:
KETOTIFEN FUMARATE, 34580-14-8, Zaditen, Zaditor, Ketotifen hydrogen fumarate, Alaway, Ketotifen (fumarate), UNII-HBD503WORO, HC 20,511 fumarate, Ketotifen fumarate (Zaditor), Ketotifen fumarate [USAN:JAN], Ketotifen fumarate salt, EINECS 252-100-0, HBD503WORO, MLS000069701, SMR000058462, 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one fumarate (1:1), C23H23NO5S, 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (E)-2-butenedioate (1:1), 4,9-Dihydro-4-(1-methylpiperidin-4-ylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophene-10-one fumarate, SR-01000075951, HC-20511, Ketotifen fumerate, (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[2,4-b]thiophen-4-one, Prestwick_743, Zaditen (TN), fumaric acid; ketotifen, HC-20511 fumarate, Opera_ID_1952, butenedioic acid; ketotifen, SCHEMBL8809, SCHEMBL8810, CHEMBL1633, MLS000758236, MLS001148200, MLS001401421, SPECTRUM1500668, C19H21NOS.C4H4O4, HMS500F13, HY-B0157A, Ketotifen fumarate (JP17/USAN), MolPort-003-666-315, REGID_for_CID_5282408, YNQQEYBLVYAWNX-WLHGVMLRSA-N, HMS1569K03, HMS1921A12, HMS2052O11, HMS2092G16, HMS2096K03, HMS2232K10, HMS2233C06, HMS3262M13, HMS3266D20, HMS3713K03, Pharmakon1600-01500668, BCP23414, Tox21_500706, AN-674, CCG-40319, MFCD00079394, NSC757415, s2024, AKOS008901371, AC-7589, BCP9000812, CCG-101110, CS-1988, KS-1206, LP00706, NC00360, NSC-757415, NCGC00094057-01, NCGC00094057-02, NCGC00094057-03, NCGC00094057-04, NCGC00094057-05, NCGC00261391-01, CPD000058462, H904, KB-53037, LS-33821, SAM001246984, SMR000653460, BCP0726000236, AB0013347, AB1009287, EU-0100706, FT-0082715, K0048, D01332, K 2628, 580K148, J-019659, SR-01000075951-1, SR-01000075951-3, SR-01000075951-4, SR-01000075951-6, Ketotifen Hydrogen Fumarate 1.0 mg/ml in Methanol (as free base), Ketotifen hydrogen fumarate, European Pharmacopoeia (EP) Reference Standard, Ketotifen for peak identification, European Pharmacopoeia (EP) Reference Standard, (E)-but-2-enedioic acid,10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one, 126939-14-8, 4,9-Dihydro-4-(1-methyl-4-piperidinylidene-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate, 4-(1-Methyl-4-piperidylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one hydrogen fumarate, 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate, CHEBI:31750

ID: 2729

chemical graph of compound 2729



InChIKey: YNVGQYHLRCDXFQ-XGXHKTLJSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CCCC[C@H]34

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5857
synonyms found at PubChem are:
LYNESTRENOL, 52-76-6, Linestrenol, Ethinylestrenol, Ethynylestrenol, Lynoestrenol, Orgametril, Orgametrol, Exluton, Endometril, Exlution, Exlutona, Orgametil, 3-Desoxynorlutin, Ethynloestrenol, Exluten, Lynenol, Lynstranol, Ethinyloestranol, Ethinyl oestrenol, Org 485-50, IND 1006, Linestrenolo [DCIT], NSC-37725, 17alpha-Ethynylestrenol, 17-alpha-Ethynylestrenol, 17-alpha-Ethynyloestrenol, UNII-N2Z8ALG4U5, Linestrenol [INN-Spanish], Lynestrenolum [INN-Latin], CCRIS 9093, EINECS 200-151-4, Lynoestrenol [Progestins], NSC 37725, 17.alpha.-Ethynylestrenol, 19-Norpregn-4-en-20-yn-17-ol, (17alpha)-, Estr-4-en-17beta-ol, 17-ethynyl-, N2Z8ALG4U5, 17-alpha-Ethynylestr-4-en-17-beta-ol, delta4-17alpha-Ethinylestren-17beta-ol, 17-alpha-Ethynyloestr-4-en-17-beta-ol, 17-alpha-Ethinyl-17-beta-hydroxyestr-4-ene, 19-Nor-17alpha-pregn-4-en-20-yn-17-ol, 17-alpha-Ethinyl-17-beta-hydroxyoestr-4-ene, CHEBI:31790, 17-alpha-Ethynil-delta-4-estrene-17-beta-ol, (17-alpha)-19-Norpregn-4-en-20-yn-17-ol, delta(sup 4)-17-alpha-Ethinylestren-17-beta-ol, delta(sup 4)-17-alpha-Ethinyloestren-17-beta-ol, NSC37725, 19-Norpregn-4-en-20-yn-17-ol, (17.alpha.)-, (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol, 19-norpregn-4-en-20-yn-17alpha-ol, Estr-4-en-17.beta.-ol, 17-ethynyl-, 19-Nor-17-alpha-pregn-4-en-20-yn-17-ol, 19-Nor-17.alpha.-pregn-4-en-20-yn-17-ol, .DELTA.4-17.alpha.-Ethinylestren-17.beta.-ol, 19 Norpregn-4-en-20-yn-17-ol, (17alpha)-, Linesterol, Linestrenolo, Lynestrenolum, Lynestrenol [USAN:INN:JAN], HSDB 7899, (17alpha)-17-ethynylestr-4-en-17-ol, Lynestrenol [USAN:INN:BAN:JAN], Prestwick_533, AC1L1LAE, Prestwick0_000095, Prestwick1_000095, Prestwick2_000095, Prestwick3_000095, Lynestrenol (JAN/USAN), SCHEMBL37816, BSPBio_000050, SPBio_001989, 17-Ethynylestr-4-en-17-ol, BPBio1_000056, CHEMBL2107431, YNVGQYHLRCDXFQ-XGXHKTLJSA-N, HMS1568C12, HMS2095C12, HMS3712C12, BCP04136, NSC73879, ZINC3875355, LMST02030127, NSC-73879, AKOS024462708, 19-Nor-4-pregnen-20-yn-17beta-ol, CCG-220095, DB12474, LS-7125, NCGC00179676-01, AJ-46418, AK161684, AN-41632, SC-47263, L0246, ST24047514, 19-Norpregn-4-en-20-yn-17-ol,(17a)-, C13037, D01580, 052L766, 19-Nor-17alpha-pregn-4-en-20-yn-17-ol (8CI)

ID: 2730

chemical graph of compound 2730



InChIKey: YNZFFALZMRAPHQ-SYYKKAFVSA-N
SMILES: CCCCCCC(C)(C)C1=CC(=C(C=C1)[C@@H]2C[C@@H](CC[C@H]2CCCO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 104895
synonyms found at PubChem are:
CP55940, CP-55940, UNII-KFY70972J5, CP 55940, CP55,940, CP 55,940, 83003-12-7, YNZFFALZMRAPHQ-SYYKKAFVSA-N, KFY70972J5, 2-[(1r,2r,5r)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, [3H]CP55940, 83002-04-4, CP-55,940, C24H40O3, 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol, 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol, Phenol, 5-(1,1-dimethylheptyl)-2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-, rel-, Phenol, 5-(1,1-dimethylheptyl)-2-(5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-, (1alpha,2beta,5alpha)-, SR-01000075740, 5-(1,1-Dimethylheptyl)-2-(5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)phenol, 2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol, CP 56667, CP-56,667, AC1L2XOK, Lopac-C-1112, D0D6OH, D0EQ0T, Lopac0_000189, GTPL730, GTPL734, ChEMBL_75020, MLS002153159, CHEMBL48552, SCHEMBL120410, AC1Q59U5, CHEMBL559612, HMS2236E04, HMS3649D17, 83002-05-5, ZINC2568244, BDBM50072775, PDSP2_000199, PDSP2_000671, AKOS024458710, CCG-204284, LP00189, NCGC00015212-01, NCGC00024896-02, NCGC00024896-03, NCGC00024896-04, NCGC00024896-05, AN-36089, SMR001230653, CP 868388, CP-55940 [(-)-AC],XIV, CP-55940, >98% (HPLC), powder, LS-104511, EU-0100189, FT-0641893, (?)-CP-55940, C 1112, (+-)-CP 55940, SR-01000597481, SR-01000075740-1, SR-01000075740-4, SR-01000597481-1, UNII-8YX8JK1BQG component YNZFFALZMRAPHQ-SYYKKAFVSA-N, (1r,3r,4r)-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-4-(3-hydroxypropyl)cyclohexan-1-ol, 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxy-propyl)-cyclohexyl]-phenol, rel-5-(1,1-dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-phenol, (3S)-3-[3-(1-Carboxy-1-methylethoxy)phenyl]-1-piperidinecarboxylic Acid 1-[[4-(1-Methylethyl)phenyl]methyl] Ester, (S)-3-[3-(1-Carboxy-1-methylethoxy)phenyl]piperidine-1-carboxylic Acid 4-Isopropylbenzyl Ester, 5-(1,1-Dimethyl-heptyl)-2-[(4R,6R)-5-hydroxy-2-((R)-3-hydroxy-propyl)-cyclohexyl]-phenol, 86687-39-0, Phenol, 5-(1,1-dimethylheptyl)-2-(5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-,(1alpha,2beta,5alpha)-

ID: 2731

chemical graph of compound 2731



InChIKey: YODZTKMDCQEPHD-UHFFFAOYSA-N
SMILES: C(CSCCO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5447
synonyms found at PubChem are:
thiodiglycol, 2,2'-Thiodiethanol, 111-48-8, Thiodiethanol, Thiodiethylene glycol, Tedegyl, Kromfax solvent, Bis(2-hydroxyethyl) sulfide, Bis(2-hydroxyethyl)sulfide, Ethanol, 2,2'-thiobis-, 2,2'-THIOBISETHANOL, 2,2'-Thiodiglycol, Glyecine A, Di(2-hydroxyethyl) sulfide, 2,2-Thiodiethanol, Bis(2-hydroxyethyl) thioether, bis(hydroxyethyl)sulfide, beta-Hydroxyethyl sulfide, Sulfide, bis(2-hydroxyethyl), Thiodiglycolum, Tiodiglicol, Tiodiglicolo, Dihydroxyethyl sulfide, Diethanol sulfide, Bis(beta-hydroxyethyl) sulfide, beta,beta'-Dihydroxyethyl sulfide, Ethanol, 2,2'-thiodi-, 2-(2-hydroxyethylsulfanyl)ethanol, Thiodiglycol [INN], beta,beta'-Dihydroxydiethyl sulfide, Bis(beta-hydroxyethyl)sulfide, Tiodiglicolo [DCIT], 2,2'-Thiobis(ethanol), 3-Thiapentane-1,5-diol, beta-Thiodiglycol, Kromfax@ Solvent, NSC 6289, Tiodiglicol [INN-Spanish], Thiodiglycolum [INN-Latin], Bis(2-hydroxyethyl) sulphide, .beta.-Thiodiglycol, UNII-9BW5T43J04, C4H10O2S, 2-[(2-hydroxyethyl)sulfanyl]ethan-1-ol, HSDB 7482, 2,2'-Thiobis[ethanol], EINECS 203-874-3, 2,2'-sulfanediyldiethanol, .beta.-Hydroxyethyl sulfide, Bis(b-hydroxyethyl) sulfide, BRN 1236325, beta-Bis(hydroxyethyl) sulfide, AI3-05541, CHEBI:75184, .beta.-Bis(hydroxyethyl) sulfide, 2-[(2-hydroxyethyl)thio]ethanol, Bis(.beta.-hydroxyethyl) sulfide, YODZTKMDCQEPHD-UHFFFAOYSA-N, 9BW5T43J04, .beta.,.beta.'-Dihydroxyethyl sulfide, .beta.,.beta.'-Dihydroxydiethyl sulfide, NCGC00095074-01, DSSTox_CID_6878, DSSTox_RID_78233, DSSTox_GSID_26878, 2,2'-sulfobisethanol, 2-(2-hydroxyethylthio)ethan-1-ol, CAS-111-48-8, Kromfax Solvenl, Glyecine l, Ethanol,2'-thiodi-, Ethanol,2'-thiobis-, 2-hydroxyethyl sulfidl, 2-Hydroxyethyl Sulfide, Spectrum_001701, beta-hydroxyethyl sulfid, 2,2'-Thiodi-Ethanol, 2,2'-Thiobis-Ethanol, AC1L1KDE, AC1Q7DBQ, Spectrum2_000407, Spectrum4_000213, 2,2 -Thio-bis[ethanol], EC 203-874-3, bis(|A-hydroxyethyl)sulfidl, WLN: Q2S2Q, SCHEMBL40132, KBioGR_000845, KBioSS_002181, 1,5-dihydroxy-3-thiapentane, SPECTRUM1503325, 2-(2-hydroxyethylthio)ethanol, bis-(2-hydroxyethyl) sulphide, SPBio_000334, CHEMBL444480, SCHEMBL6679983, Jsp000864, DTXSID6026878, CTK0H5226, KBio2_002181, KBio2_004749, KBio2_007317, 2,2'-Thiodiethanol, >=99%, NSC6289, HMS1922I18, Pharmakon1600-01503325, HY-B0913, NSC-6289, ZINC1693386, Tox21_111413, Tox21_200827, CCG-39716, NSC758456, SBB060117, STL302034, AKOS009031578, Tox21_111413_1, MCULE-5502656030, NE10240, NSC-758456, NCGC00095074-02, NCGC00095074-03, NCGC00095074-05, NCGC00258381-01, AJ-30195, AN-22663, CJ-28318, LS-67064, 2,2'-Thiodiethanol, >=99.0% (GC), SBI-0051909.P002, DB-060096, TR-002273, FT-0609146, ST51046354, X3615, EN300-20661, 2,2'-Thiodiethanol, purum, >=95.0% (GC), AB00052435_02, 2,2'-Thiodiethanol, puriss., >=98.5% (GC), A802371, SR-01000872773, J-002590, S09-0119, SR-01000872773-1, F0001-0242, InChI=1/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H, 2,2'-Thiodiethanol, >=99.0%, suitable for amino acid analysis

ID: 2732

chemical graph of compound 2732



InChIKey: YOEWQQVKRJEPAE-UHFFFAOYSA-L
SMILES: C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 22475
synonyms found at PubChem are:
Succinylcholine chloride, 71-27-2, Succinyldicholine chloride, suxamethonium chloride, Midarine, Scoline, Anectine, Lysthenon, Succinylforte, Lysthenone, Myoplegine, Pantolax, Sukolin, Suxcert, Suxinyl, Succin, Suxamethonii chloridum, Succinyl-asta, Scoline chloride, Suxamethonium dichloride, Anectine chloride, Quelicin chloride, Chlorsuccinylcholin, Sucostrin chloride, Diacetylcholine dichloride, Succinylcholine dichloride, Succicuran, Sucostrin, Bis(succinyldichlorocholine), Cloruro de suxametonio, Suxamethionium chloride, Succamethonium chloratum, Succinoylcholine chloride, Chlorure de succinilcoline, Quelicin Preservative Free, UNII-I9L0DDD30I, Choline, chloride succinate, Choline succinate dichloride, Succinyl bischoline chloride, Succinylbischoline dichloride, 2-Dimethylaminoethyl succinate dimethochloride, Chlorsuccinylcholin [German], Sukcinylcholinchlorid [Czech], Succinilcolina cloruro [DCIT], Choline, succinyl-, dichloride, Choline chloride succinate (2:1), Chlorure de succinilcoline [French], Cloruro di succinilcolina [Italian], Suxamethonii chloridum [INN-Latin], EINECS 200-747-4, NSC 49132, Cloruro de suxametonio [INN-Spanish], I9L0DDD30I, Bis(2-dimethylaminoethyl)succinate bis(methochloride), AI3-51679, CHEBI:61219, (2-Hydroxyethyl)trimethylammonium chloride succinate, Choline, chloride, succinate (2:1), Choline, hydroxide, succinate (2:1), dihydrochloride, Succinic acid, diester with choline chloride, Succinyl-bis(N-(2-oxyethyl)trimethylammonium)-dichlorid, NCGC00094357-01, 3,8-Dioxa-4,7-dioxodercan-1,10-bis(trimethylammonium)dichlorid, Anectine (TN), Succinic acid, bis(beta-dimethylaminoethyl) ester, dimethochloride, DSSTox_CID_3603, DSSTox_RID_77103, DSSTox_GSID_23603, Suxamethonium chloride (INN), Suxamethonium chloride [INN], Q-201750, 306-40-1 (Parent), 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride, CAS-71-27-2, Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl-), dichloride, Sukcinylcholinchlorid, C14H28N2O4, Succinilcolina cloruro, Cloruro di succinilcolina, Succinylcholine chloride [USAN], Quelicin (TN), Succinylcholine chloride [USAN:USP], SUXAMETHONE, Succinylchline chloride, Sucinylcholine chloride, CHEMBL983, AC1L2KG8, SCHEMBL41536, anhydrous suxamethonium chloride, C14H30Cl2N2O4, Succinylcholine chloride (USP), DTXSID1023603, anhydrous succinylcholine chloride, CTK8B3901, suxamethonium chloride (anhydrous), HMS3263G22, Suxamethonium chloride, 98% 1g, anhydrous succinylcholine dichloride, succinylcholine chloride (anhydrous), Tox21_111268, Tox21_501080, anhydrous succinyldicholine dichloride, ANW-43407, succinylcholine dichloride (anhydrous), AKOS015961173, Tox21_111268_1, AC-4688, CCG-222384, LP01080, MCULE-2070369236, Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl-, dichloride, succinyldicholine dichloride (anhydrous), NCGC00015971-05, NCGC00261765-01, AN-11707, BC205664, LS-53219, TR-023470, EU-0101080, S0149, W0076, D00766, S 8251, C-50686, SR-01000075346, SR-01000075346-2, 2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethylethanaminium Chloride, trimethyl-[2-[4-oxo-4-[2-(trimethylammonio)ethoxy]butanoyl]oxyethyl]ammonium dichloride, trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium dichloride, 10168-63-5

ID: 2733

chemical graph of compound 2733



InChIKey: YOSHYTLCDANDAN-UHFFFAOYSA-N
SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3749
synonyms found at PubChem are:
irbesartan, 138402-11-6, Aprovel, Avapro, Karvea, SR-47436, BMS-186295, BMS 186295, Irbesartan [USAN:INN], SR 47436, Irbesarran, Lrbesartan, Irbetan, [3H]irbesartan, UNII-J0E2756Z7N, Avapro (TN), CHEMBL1513, 8-butyl-7-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-7,9-diazaspiro[4.4]non-8-en-6-one, CHEBI:5959, 3-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one, C25H28N6O, YOSHYTLCDANDAN-UHFFFAOYSA-N, J0E2756Z7N, 2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one, 2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one, Irbesartan HCl, NCGC00095122-01, DSSTox_CID_3169, 2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one, 2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one, DSSTox_RID_76900, DSSTox_GSID_23169, 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 2-BUTYL-3-[[2'-(2H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE, 3-BUTYL-2-[[4-[2-(2H-TETRAZOL-5-YL)PHENYL]PHENYL]METHYL]-2,4-DIAZASPIRO[4.4]NON-3-EN-1-ONE, Irbesartan Krka, Irbesartan BMS, Irbesartan Winthrop, 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one, SMR000466306, CAS-138402-11-6, ifirmasta, HSDB 8215, Irbesartan [USAN:USP:INN:BAN], Irbesartan ,(S), 2-BUTYL-3-((4-[2-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]PHENYL)METHYL)-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE, 2-BUTYL-3-([4-[2-(2H-1,2,3,4-TETRAZOL-5-YL)PHENYL]PHENYL]METHYL)-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE, 2-butyl-3-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one, 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE, 2-butyl-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, 3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one, Aprovel (TN), Avalide (TN), Irbesartan (Avapro), Irbesartan(Avapro)/, Karvea (TN), IRBESARTIN, PubChem21382, Spectrum_001751, BMS Brand of Irbesartan, AC1L1GMK, Spectrum2_001675, Spectrum3_000994, Spectrum4_001122, Spectrum5_001288, D00JAU, D0F8KG, SCHEMBL4246, BSPBio_002687, GTPL589, KBioGR_001603, KBioSS_002231, MLS000759408, MLS001424099, BIDD:GT0347, Irbesartan (JAN/USAN/INN), SPECTRUM1504259, SPBio_001889, GTPL6908, Jsp002315, DTXSID0023169, Irbesartan (JP17/USAN/INN), KBio2_002231, KBio2_004799, KBio2_007367, KBio3_001907, KS-00000ISW, EBD8758, Bristol Myers Brand of Irbesartan, MolPort-003-666-550, MolPort-006-167-687, BCPP000202, HMS1922J05, HMS2051L08, HMS2093E16, HMS2232F23, HMS3370B06, HMS3393L08, HMS3715L04, Pharmakon1600-01504259, SanofiWinthrop Brand of Irbesartan, BCP02004, HY-B0202, ZINC3872931, Tox21_111433, ABP000523, AC-537, BDBM50042235, CCG-39091, MFCD00864464, NSC758696, STK645362, AKOS005576396, AKOS015895353, Irbesartan, >=98% (HPLC), powder, Tox21_111433_1, AB07472, AM90289, BCP9000792, CCG-101012, CS-2140, DB01029, KS-1151, MCULE-9617953373, NC00262, NSC-758696, NCGC00095122-02, NCGC00095122-03, NCGC00095122-05, 4CA-0654, AK-57149, AN-15743, BC207567, BR-57149, CPD000466306, H931, KB-52707, LS-60064, SAM001246548, SC-08814, SBI-0206769.P001, AB0013366, AB1009632, TL8000875, FT-0601598, I0859, S1507, ST24028252, C07469, D00523, J10394, S-1797, 54246-EP2270011A1, 54246-EP2295406A1, 54246-EP2295422A2, 54246-EP2298772A1, 54246-EP2298776A1, 54246-EP2298779A1, 54246-EP2301923A1, 54246-EP2301931A1, 54246-EP2305219A1, 54246-EP2308562A2, 54246-EP2308839A1, AB00639954-06, AB00639954_07, AB00639954_08, 402I116, A807387, L000319, SR-05000001997, I06-0690, Q-201249, SR-05000001997-1, (-)-Styrene glycol; (R)-(-)-Phenylethylene glycol, BRD-K60038276-001-02-5, BRD-K60038276-001-03-3, BMS-186295, SR-47436,Aprovel, Karvea, Irbesartan, Irbesartan, European Pharmacopoeia (EP) Reference Standard, Irbesartan, United States Pharmacopeia (USP) Reference Standard, 2-butyl-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[, 2-butyl-3-[2'-(1h-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[, Irbesartan, Pharmaceutical Secondary Standard; Certified Reference Material, 2-butyl-3-[ p -( o -1 H -tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one, 2-butyl-3-[ p-(o-1 H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one, 2-(n-butyl)-3-[[2'-(tetrazol-5-yl)biphenyl-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, 2-BUTYL-3-[[2'-(2H-TETRAZOL-5-YL)-4-BIPHENYLYL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE, 2-butyl-3-{[2''-(1H-tetrazol-5-yl)[1,1''-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-{[2''-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one, 2-n-butyl-3-<<2'-(1H-tetrazol-5-yl)biphenyl-4-yl>methyl>-1,3-diazaspiro<4.4>non-1-en-4-one;, 3-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one, 3-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one, 8-butyl-7-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]-7,9-diazaspiro[4.4]non-8-en-6-one

ID: 2734

chemical graph of compound 2734



InChIKey: YOURSPNOEWYAKO-UHFFFAOYSA-N
SMILES: C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)I.Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957592
synonyms found at PubChem are:
L-750,667 trihydrochloride, 1021868-80-3, NCGC00094070-01, EU-0100722, CHEMBL1496166, CTK8G0467, DTXSID10474692, L-750,667 trihydrochloride, solid, LP00722, L-133, SR-01000075972, SR-01000075972-1, ( inverted question mark)-3-[4-Iodophenyl)-1-piperazyl] methylpyrrolo [2,3-b] pyrimidine, 3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride

ID: 2735

chemical graph of compound 2735



InChIKey: YOYAIZYFCNQIRF-UHFFFAOYSA-N
SMILES: C1=CC(=C(C(=C1)Cl)C#N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3031
synonyms found at PubChem are:
2,6-Dichlorobenzonitrile, dichlobenil, 1194-65-6, Dichlobanil, Casoron, Benzonitrile, 2,6-dichloro-, Casaron, Prefix D, DU-Sprex, Decabane, Surfassol, Casoron 133, DBN (the herbicide), 2,6-Dichlorophenyl cyanide, 2,6-DBN, Niagara 5,996, DBN (pesticide), 2,6-DICHLOROBENZNITRILE, Code H 133, Cyclomec, Dyclomec, Norosac, Casoron gsr, Nia 5996, Casoron G-4, Casoron G-10, Casoron G20 SR, Casoron W-50, Caswell No. 297, Carsoron, 2,6-Dichlorbenzonitril, 2,6-Dichlorobenzoic acid nitrile, H 133, NSC 521490, UNII-N42NR4196R, Dichlobenil [ANSI:BSI:ISO], CCRIS 1470, HSDB 312, Niagara 5006, 2,6-Dichlorbenzonitril [German], EINECS 214-787-5, 2,6-dichloro-benzonitrile, EPA Pesticide Chemical Code 027401, BRN 1909167, CHEBI:943, AI3-26665, YOYAIZYFCNQIRF-UHFFFAOYSA-N, N42NR4196R, H 1313, 2,6-dichlorobenzenecarbonitrile, Casoron G, (14-C)2,6-Dichlorobenzonitrile, Casoron G4, BH Prefix D, DICHLORBENIL, DICLOBENIL, Fyducit (Salt/Mix), Fydumas (Salt/Mix), DBN STANDARD, Spectrum_001835, dichlobenil, dichlobanil, CASORON(R), Fydulan G (Salt/Mix), SpecPlus_000436, 2.6-Dichlorobenzonitrile, Benzonitrile,6-dichloro-, Spectrum2_001886, Spectrum3_000828, Spectrum4_000668, Spectrum5_001968, WLN: NCR BG FG, ACMC-209a2v, EC 214-787-5, AC1L1F0N, 2,4-Dbn, Benzonitrile,2,6-dichloro-, DSSTox_CID_12365, DSSTox_RID_78927, DSSTox_GSID_32365, SCHEMBL55606, BSPBio_002355, KBioGR_001075, KBioSS_002340, SPECTRUM330036, KSC174Q7N, DivK1c_006532, SPBio_001792, 2,6-DCBN, AC1Q4R88, CHEMBL3039332, DTXSID5032365, 2,6-Dichlorobenzonitrile, 97%, CTK0H4876, KBio1_001476, KBio2_002337, KBio2_004905, KBio2_007473, KBio3_001855, KS-00000ECV, TIMTEC-BB SBB041083, MolPort-000-872-210, ZINC157318, AKOS BBS-00004654, Tox21_300791, ANW-17333, BBL011045, CCG-39424, CK1056, LABOTEST-BB LT01148261, LABOTEST-BB LT03333499, MFCD00001781, NSC521490, SBB041083, STK802216, AKOS000269672, AS02651, LS11439, MCULE-1360009724, NE18461, NSC-521490, PS-5306, RTR-003270, TRA0085563, Dichlobenil 10 microg/mL in Cyclohexane, NCGC00094529-01, NCGC00094529-02, NCGC00094529-03, NCGC00094529-04, NCGC00094529-05, NCGC00094529-06, NCGC00254695-01, 104809-79-2, AC-10715, AJ-14983, AN-48824, CJ-01635, Dichlobenil 100 microg/mL in Cyclohexane, I898, KB-18201, LS-38675, SC-25936, TL806241, ZB006641, CAS-1194-65-6, Dichlobenil 100 microg/mL in Acetonitrile, AB0013926, DB-030805, KB-226134, ST2415916, TR-003270, D1137, FT-0081742, FT-0610598, FT-0695514, H-133, ST45027659, C11040, Dichlobenil, PESTANAL(R), analytical standard, 33182-EP2305655A2, 33182-EP2311815A1, 33182-EP2371823A1, I01-2577, Q-200960, Q-200961, BRD-K43714461-001-02-8, InChI=1/C7H3Cl2N/c8-6-2-1-3-7(9)5(6)4-10/h1-3

ID: 2736

chemical graph of compound 2736



InChIKey: YPDVTKJXVHYWFY-UHFFFAOYSA-N
SMILES: CC(C)NNC(=O)C1=CC=NC=C1.OP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9367
synonyms found at PubChem are:
Iproniazid phosphate, 305-33-9, Iproniazide phosphate, N'-Isopropylisonicotinohydrazide phosphate, Marsilid phosphate, Isoproniazid phosphate, Iproniazid as phosphate, Iproniazid dihydrogen phosphate, Iproniazid phosphate (VAN), UNII-8DE00V62TV, Iproniazid (phosphate), 1-Isopropyl-2-isonicotinylhydrazine phosphate, EINECS 206-164-1, NSC 81850, AI3-62177, MLS000069781, 8DE00V62TV, ISONICOTINIC ACID, 2-ISOPROPYLHYDRAZIDE, PHOSPHATE, SMR000058459, 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, phosphate (1:1), NSC81850, SR-01000075585, phosphoric acid;N'-propan-2-ylpyridine-4-carbohydrazide, 305-33-9{phosphate}, C9H13N3O.H3O4P, Marsilid (TN), Prestwick_280, Iproniazid(phosphate), Opera_ID_317, Iproniazid phosphate salt, Iproniazid (as phosphate), AC1L1SW7, AC1Q5Q8G, Isonicotinic acid, phosphate, MLS002222196, SCHEMBL158555, CHEMBL1256361, MolPort-003-941-839, HMS1568D13, HMS2095D13, HMS2235O15, HMS3262A07, HMS3372C05, HMS3712D13, HY-B0886, KS-00001F9Q, Tox21_500643, ACM305339, Isonicotinic acid, phosphate (1:1), NSC-81850, AKOS024258484, CCG-220176, CCG-221947, LP00643, NCGC00094010-01, NCGC00094010-02, NCGC00261328-01, AK158395, LS-84938, 4CH-022556, EU-0100643, ST24048128, D08085, I 7627, Isonicotinic acid 2-isopropylhydrazide phosphate salt, SR-01000075585-1, SR-01000075585-5, I14-60534, phosphoric acid; N'-propan-2-ylpyridine-4-carbohydrazide, Isonicotinic acid, 2-isopropylhydrazide, phosphate (1:1), Isonicotinic acid, 2-isopropylhydrazide, phosphate (1:1) (8CI), 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, phosphate (1:1) (9CI)

ID: 2737

chemical graph of compound 2737



InChIKey: YPHMISFOHDHNIV-FSZOTQKASA-N
SMILES: C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6197
synonyms found at PubChem are:
cycloheximide, 66-81-9, ACTIDIONE, Cicloheximide, NARAMYCIN A, Kaken, Actidion, Actidone, Hizarocin, Naramycin, Neocycloheximide, Acti-Aid, Actispray, Actidione PM, Cicloheximida, Cicloheximidum, Cycloheximid, Zykloheximid, Actidione BR, Actidione TGF, Aktidion [Czech], NSC 185, Cycloheximide [USAN], Caswell No. 270A, NSC-185, Acti-dione BR, Cicloheximidum [INN-Latin], Cicloheximida [INN-Spanish], CCRIS 937, U-4527, CBC 500046, NSC185, C15H23NO4, HSDB 1552, TCMDC-125838, 3-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, EINECS 200-636-0, U 4527, UNII-98600C0908, Cycloheximide [BSI:ISO], Cycloheximide, High Purity, EPA Pesticide Chemical Code 043401, BRN 0088868, Aktidion, NM-MCD 80, 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione, AI3-15541, CHEMBL123292, CHEBI:27641, GNF-PF-5118, 3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, beta-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 3-(2R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethylglutarimide, Cicloheximide (INN), Cicloheximide [INN], (1S-(1alpha(S*),3alpha,5beta))-4-(2-(3,5-Dimethyl-2-oxo-cyclohexyl))-2-hydroxyethyl-2,6-piperidinedione, 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-, CX, Cycloheximide (USAN), FT 3422-2, DSSTox_CID_4882, 4-((2R)-2-((1S,3S,5S)-(3,5-Dimethyl-2-oxocyclohexyl))-2-hydroxyethyl)piperidine-2,6-dione, 4-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)piperidine-2,6-dione, DSSTox_RID_77565, Cyclohemimide, Cyclohexamide, DSSTox_GSID_24882, 98600C0908, TZA, .beta.-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione, 4-[(2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]azaperhydro ine-2,6-dione, SMR000686067, Glutarimide, 3-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, SR-01000597484, SR-05000001596, Acti-dione PM, Acti-dione TGF, CAS-66-81-9, NCGC00024910-01, Prestwick_976, actidione, actispray, naramycin a, hizarocin, Spectrum_001344, Prestwick0_000790, Prestwick1_000790, Prestwick2_000790, Prestwick3_000790, Spectrum2_000900, Spectrum3_001510, Spectrum4_000914, Spectrum5_001635, kaken, U-4527, D06ZWX, cid_6197, SCHEMBL26617, BSPBio_000900, BSPBio_003159, KBioGR_001408, KBioSS_001824, 5-21-13-00434 (Beilstein Handbook Reference), ksc-8-190, MLS001055333, MLS002154001, DivK1c_000050, SPECTRUM1502112, SPBio_000720, SPBio_002839, 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl] glutarimide, 4-[2-(3,6-piperidinedione, AC1L1M03, BPBio1_000990, GTPL5433, 4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione, DTXSID6024882, HMS500C12, KBio1_000050, KBio2_001824, KBio2_004392, KBio2_006960, KBio3_002659, MolPort-002-070-550, NINDS_000050, YPHMISFOHDHNIV-FSZOTQKASA-N, ZX-AFC000592, HMS1570M22, HMS1921L04, HMS2092D10, HMS2097M22, HMS3714M22, KUC105858N, Pharmakon1600-01502112, Cycloheximide, Streptomyces griseus, 2,6-Piperidinedione, 4-((2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, ZINC3872170, Tox21_113580, Tox21_201158, Tox21_303652, AN-189, BDBM50080528, BI2521, CCG-39902, Cycloheximide, >=93.0% (HPLC), MFCD00082346, NSC758187, SBB005972, AKOS024282670, Tox21_113580_1, CC-2256, CS-4985, LS-1558, NSC-758187, IDI1_000050, NCGC00017363-05, NCGC00017363-06, NCGC00017363-07, NCGC00017363-08, NCGC00017363-10, NCGC00024910-02, NCGC00024910-03, NCGC00024910-04, NCGC00024910-05, NCGC00024910-06, NCGC00169964-05, NCGC00257430-01, NCGC00258710-01, AS-14624, BP-12396, CC-26065, HY-12320, L918, NCI60_001540, SC-19304, ST057527, SBI-0051732.P002, WLN: T6VMVTJ E1YQ- BL6VTJ D1 F1, Cycloheximide, from microbial, >=94% (TLC), C-9217, C06685, Cycloheximide solution, 0.1%, for microbiology, D03625, M01527, AB00052279_08, Cycloheximide, PESTANAL(R), analytical standard, 082C346, C-17728, Cycloheximide, Biotechnology Performance Certified, Cycloheximide, Antibiotic for Culture Media Use Only, SR-01000597484-1, SR-01000597484-4, SR-05000001596-1, SR-05000001596-3, SR-05000001596-4, BRD-K36055864-001-05-1, BRD-K36055864-001-07-7, BRD-K36055864-001-09-3, BRD-K36055864-001-16-8, 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione, 2, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-, 4-[(2R)-2-[(1S,3S,5R)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione, Cycloheximide solution, Ready-Made Solution, microbial, 100 mg/mL in DMSO, 0.2 mum filtered

ID: 2738

chemical graph of compound 2738



InChIKey: YPIDZFLQKNEKRA-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1O)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 238769
synonyms found at PubChem are:
5-methoxy-2-methylbenzene-1,3-diol, 2,6-DIHYDROXY-4-METHOXYTOLUENE, 6307-89-7, NSC43301, Spectrum_001926, Spectrum2_001803, Spectrum3_001718, Spectrum4_001799, Spectrum5_000477, 2-Methyl-5-methoxyresorcinol, BSPBio_003336, KBioGR_002380, KBioSS_002468, SPECTRUM1600025, SPBio_001785, AC1L61Q5, AC1Q7A07, SCHEMBL1607351, CHEMBL1374151, CTK5B7427, KBio2_002461, KBio2_005029, KBio2_007597, KBio3_002556, DTXSID40285950, YPIDZFLQKNEKRA-UHFFFAOYSA-N, ZINC1676018, CCG-38449, NSC-43301, 1,3-Benzenediol,5-methoxy-2-methyl-, SDCCGMLS-0066876.P001, NCGC00095758-01, NCGC00095758-02, SR-05000002385, SR-05000002385-1, BRD-K35568433-001-02-3, BRD-K35568433-001-03-1

ID: 2739

chemical graph of compound 2739



InChIKey: YPTJKHVBDCRKNF-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=CC=C1O)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 69687
synonyms found at PubChem are:
2',6'-Dihydroxyacetophenone, 699-83-2, 1-(2,6-Dihydroxyphenyl)ethanone, 2,6-Dihydroxyacetophenone, 2-Acetylresorcinol, Resorcinol, 2-acetyl-, 1-(2,6-dihydroxyphenyl)ethan-1-one, 2,6-dihydroxy acetophenone, gamma-Resacetophenone, Ethanone, 1-(2,6-dihydroxyphenyl)-, UNII-88BO51G3Y2, 1,3-Benzenediol, 2-acetyl-, NSC 615, .gamma.-Resacetophenone, 2, 6-Dihydroxyacetophenone, Acetyl-2,6-dihydroxybenzene, 2',6'-dihydroxy-acetophenone, CHEMBL454739, YPTJKHVBDCRKNF-UHFFFAOYSA-N, 88BO51G3Y2, 1-(2,6-dihydroxyphenyl)-ethanone, Acetophenone, 2',6'-dihydroxy- (8CI), Ethanone, 1-(2,6-dihydroxyphenyl)- (9CI), 1-acetyl-2,6-dihydroxybenzene, Acetophenone, 2',6'-dihydroxy-, EINECS 211-833-6, 2-Acetyl-Resorcinol, mono acetyl resorcinol, PubChem3378, ACMC-209obz, AC1L2CFQ, EC 211-833-6, 2-Acetylbenzene-1,3-diol, AC1Q1JI6, Acetophenone,6'-dihydroxy-, 2-Acetyl-1,3-Benzenediol, dihydroxyacetophenone(2,6-), 2;,6;-Dihydroxyacetophenone, Ethanone,6-dihydroxyphenyl)-, KSC352Q3J, BIDD:ER0607, SCHEMBL105807, 2',6'-dihydroxy acetophenone, 2-Acetyl-1,3-dihydroxybenzene, AC1Q5D59, NSC615, (2',6'-dihydroxy)acetophenone, 2'',6''-dihydroxyacetophenone, 2 ',6 '-Dihydroxyacetophenone, 2/',6/'-Dihydroxyacetophenone, 2\',6\'-Dihydroxyacetophenone, CTK2F2834, laquo gammaRaquo -resacetophenone, YPTJKHVBDCRKNF-UHFFFAOYSA-, DTXSID00220185, NSC-615, MolPort-000-154-541, ZINC157768, ACT00503, 1-(2,6-dihydroxy-phenyl)-ethanone, 2',6'-Dihydroxyacetophenone, 97%, ANW-35805, BDBM50249071, HTS001838, MFCD00002270, SBB063298, STL195537, AKOS000299253, CS-W019984, FS-2546, LS-3428, MCULE-4595729640, RP21566, RTR-033313, TRA0041998, 1-(2,6-Dihydroxyphenyl)ethanone, 9CI, NCGC00166008-01, AC-10724, AJ-15104, AN-47304, BR-47368, CJ-01713, KB-18349, SC-06375, SY001633, ZB006765, AB0011052, DB-020214, TL8004919, TR-033313, D1716, FT-0610665, ST24032156, ST50331349, KS-00000161, 99D832, D-3400, M-3163, AB-131/40185723, I01-1172, W-203531, 1-(2,6-Dihydroxyphenyl)ethanone (2',6'-Dihydroxyacetophenone), 2',6'-Dihydroxyacetophenone, matrix substance for MALDI-MS, >=99.5%, 2',6'-Dihydroxyacetophenone, matrix substance for MALDI-MS, >=99.5% (HPLC), Ultra pure, InChI=1/C8H8O3/c1-5(9)8-6(10)3-2-4-7(8)11/h2-4,10-11H,1H3

ID: 2740

chemical graph of compound 2740



InChIKey: YQBNJPACAUPNLV-UHFFFAOYSA-N
SMILES: CC(C)C1=C(C2=C(O1)C=C3C(=C2)C=CC(=O)O3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8616
synonyms found at PubChem are:
Peucedanin, Peutsedin, Oreoselone methyl ether, 133-26-6, 4-Methoxy-5-isopropylfuro(2,3:6,7)coumarin, UNII-N021633LOB, BRN 0234473, CHEBI:8034, 3-Methoxy-2-(1-methylethyl)-7H-furo(3,2-g)(1)benzopyran-7-one, N021633LOB, 6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylic acid delta-lactone, 2-isopropyl-3-methoxy-7H-furo[3,2-g]chromen-7-one, 5-Benzofuranacrylic acid, 6-hydroxy-2-isopropyl-3-methoxy-, delta-lactone, 3-methoxy-2-(propan-2-yl)-7H-furo[3,2-g]chromen-7-one, 7H-FURO(3,2-g)(1)BENZOPYRAN-7-ONE, 2-ISOPROPYL-3-METHOXY-, Spectrum_001546, SpecPlus_000952, AC1L1RCV, Spectrum2_000729, Spectrum3_001647, Spectrum4_001666, Spectrum5_000571, Oprea1_190644, Oprea1_837278, BSPBio_003373, KBioGR_002191, KBioSS_002026, 5-19-06-00042 (Beilstein Handbook Reference), MLS001049116, DivK1c_007048, SPECTRUM1504168, SPBio_000658, MEGxp0_001552, SCHEMBL2249089, ZINC1912, CHEMBL1410943, CTK4B8448, KBio1_001992, KBio2_002026, KBio2_004594, KBio2_007162, KBio3_002593, YQBNJPACAUPNLV-UHFFFAOYSA-, DTXSID10157897, MolPort-000-882-022, HMS2675C08, CCG-40070, STK396320, AKOS000278122, MCULE-2664497001, SDCCGMLS-0066802.P001, NCGC00095695-01, NCGC00095695-02, LS-70731, SMR000102964, ST50909203, C09283, AB00053108-02, 2-isopropyl-3-methoxy-furo[3,2-g]chromen-7-one, 3-methoxy-2-propan-2-ylfuro[3,2-g]chromen-7-one, 6-methoxy-7-(methylethyl)furano[3,2-g]chromen-2-one, BRD-K72034655-001-02-1, 7H-Furo[3,2-g][1]benzopyran-7-one,3-methoxy-2-(1-methylethyl)-, NCGC00095695-03!3-methoxy-2-propan-2-ylfuro[3,2-g]chromen-7-one, 3-Methoxy-2-(1-methylethyl)-7 H -furo[3,2- g ][1]benzopyran-7-one; 2-Isopropyl-3-methoxy-7 H -furo[3,2- g ][1]benzopyran-7-one, InChI=1/C15H14O4/c1-8(2)14-15(17-3)10-6-9-4-5-13(16)18-11(9)7-12(10)19-14/h4-8H,1-3H3

ID: 2741

chemical graph of compound 2741



InChIKey: YQGOJNYOYNNSMM-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)O)Br)Br)Br)C(=O)O.[Na+]

biological descriptors:

CFTR relevance: stimulates CFTR, inhibites it at high concentrations

Category:
Influence on CFTR function inconsistent assignment
Order of interaction unknown
subcellular compartment unknown

reference list:

"U Russ" "A Bachmann" "U Quast" "S Waldegger"


CID is 24180873
synonyms found at PubChem are:
Bromoeosine, Sodium eosine, Bronze Bromo, Certiqual Eosine, Aizen eosine GH, Bromo Fluorescein, Eosine A, Eosine B, Eosine J, Eosine w/s, Bromo B, Eosine BS, Eosine DA, Eosine FA, Eosine GF, Eosine OJ, Eosine YB, Eosine YS, Phloxine Toner B, Pure Eosine YY, Toyo Eosine G, Eosine BPC, Bromo FL, Bromo TS, Bromo XX, Eosin YS, Bromo JPS, Eosine 3G, Eosine 3Y, Eosine BS-SF, Bromo 4D, Bromo 4DC, Bromo 4DL, Hidacid White Bromo, Symuler Eosin Toner, Eosine K Salt Free, Eosine DWC 73, Hidacid Boiling Bromo, 1903 Yellow Pink, Tetrabromofluorescein D, Tetrabromofluorescein S, Irgalite Bronze Red CL, Hidacid Eosine Soda Salt, Hidacid Bromo acid regular, Hidacid Dibromo Fluorescein, Phloxine Red 20-7600, Phlox Red Toner X-1354, Eosine Extra Conc. A. Export, 11445 Red, 11731 Red, C.I. 45380, NSC2087, NSC667238, 548-26-5, NSC-2087, NSC-667238, Fluorescein,4',5',7'-tetrabromo-, disodium salt, Benzoic acid,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)-, disodium salt

ID: 2742

chemical graph of compound 2742



InChIKey: YQLZOAVZWJBZSY-UHFFFAOYSA-N
SMILES: C(CCCCCN)CCCCN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1317
synonyms found at PubChem are:
1,10-Diaminodecane, 1,10-Decanediamine, 646-25-3, decane-1,10-diamine, Decyldiamine, Decamethylenediamine, 1,10-Decamethylenediamine, UNII-6GPF1OF9Y1, EINECS 211-471-9, NSC 10400, BRN 1738591, 6GPF1OF9Y1, YQLZOAVZWJBZSY-UHFFFAOYSA-N, 1.10-diaminodecane, 10-amino-decyl-amine, 1,10-decane diamine, 1,10-diamino decane, 1,10-Decylenediamine, ACMC-209nnf, Lopac-D14204, EC 211-471-9, AC1L1B7K, AC1Q54FN, DA10; Decamethylenediamine, Lopac0_000458, SCHEMBL25919, 4-04-00-01368 (Beilstein Handbook Reference), WLN: Z10Z, 1,10-Diaminodecane, 97%, CHEMBL570383, DTXSID8060953, CTK2F3855, KS-00000WFC, MolPort-000-732-126, HMS3261K18, NSC10400, ZINC1706212, Tox21_500458, ANW-34921, NSC-10400, PDSP1_000331, PDSP2_000329, STK618544, AKOS005552456, CCG-204550, LP00458, MCULE-8635244158, NE10556, RTR-022115, TRA0019550, NCGC00015388-01, NCGC00015388-02, NCGC00015388-03, NCGC00015388-04, NCGC00093873-01, NCGC00093873-02, NCGC00261143-01, AJ-30653, AN-47081, AS-14350, AT-14564, K834, KB-64138, LS-59288, SC-74376, DB-054701, TL8004605, TR-022115, D0085, EU-0100458, FT-0606031, ST50330594, D14204, SR-01000075446, S14-1029, SR-01000075446-1, W-104826, 1062154-50-0, 95931-01-4

ID: 2743

chemical graph of compound 2743



InChIKey: YQNHFSXRABPJLP-BTJKTKAUSA-N
SMILES: CC(CC1=CNC2=C1C=C(C=C2)O)N.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9922558
synonyms found at PubChem are:
alpha-Methyl-5-hydroxytryptamine maleate, 97469-12-0, 304-52-9, alpha-Methylserotonin maleate, SR-01000075558, EU-0100823, SCHEMBL1321599, CHEMBL1256710, DTXSID70432894, MolPort-003-958-628, HMS3262F07, alpha-methyl serotonin maleate salt, Tox21_500823, ACM304529, BN0060, AKOS024458563, CCG-222127, LP00823, NCGC00094154-01, NCGC00261508-01, DB-022462, alpha-Methylserotonin maleate salt, >=98% (HPLC), SR-01000075558-1, SR-01000075558-3, ( inverted exclamation markA)-3-(2-Aminopropyl)indol-5-ol maleate salt

ID: 2744

chemical graph of compound 2744



InChIKey: YQZBAXDVDZTKEQ-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 71399
synonyms found at PubChem are:
Loxapine succinate, 27833-64-3, Loxapine succinate salt, Loxapac, Cloxazepin, Daxolin, Lederle, Loxapine (succinate), UNII-X59SG0MRYU, Loxapine,succinate, Loxapine, Succinate, CCRIS 1917, EINECS 248-682-0, X59SG0MRYU, CL 71563, CPD000058470, MLS000069383, NCGC00016160-02, SMR000058470, Loxitane (TN), CAS-27833-64-3, 2-chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]oxazepine succinate, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine succinate (1:1), DSSTox_CID_25227, DSSTox_RID_80764, DSSTox_GSID_45227, C22H24ClN3O5, CL-71563, W-107092, CHEBI:6549, 1977-10-2 (Parent), Butanedioic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine (1:1), Butanedioic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine (1:1), Succinic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine (1:1), Succinic acid, compound with 2-chloro-11-(4-methylpiperazin-1-yl)dibenz(b,f)(1,4)oxazepine (1:1), AZ-004, SR-01000002971, Loxapine succinate [USAN], Loxapine succinate [USAN:USP], Staccato-loxapine, butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, Loxipine Succinate, Prestwick_304, Lopac-L-106, AC1Q5VQU, Opera_ID_1518, Loxapine succinate (USP), SCHEMBL41643, MLS000758291, MLS001146961, MLS001401432, MLS002222201, SPECTRUM2300242, Loxapine succinate salt, solid, REGID_for_CID_71399, AC1L2G38, CHEMBL1201155, DTXSID3045227, CTK4G0318, AOB5330, MolPort-003-666-776, ZX-AFC001324, HMS1568K06, HMS1922L14, HMS2051E05, HMS2093N20, HMS2095K06, HMS2232N05, HMS3262O21, HMS3374F02, HMS3393E05, HMS3652O10, HMS3712K06, Pharmakon1600-02300242, Tox21_110311, Tox21_500720, AZ-104, CCG-39497, HY-17390A, MFCD00069298, NSC759578, s4086, AKOS015994711, Tox21_110311_1, CS-4285, KS-1083, LP00720, NC00011, NSC-759578, VA11204, NCGC00016160-01, NCGC00016160-03, NCGC00016160-04, NCGC00016160-05, NCGC00021145-11, NCGC00094068-01, NCGC00094068-02, NCGC00094068-03, NCGC00261405-01, O287, SAM001247061, LS-147408, EU-0100720, FT-0653022, VU0239541-8, D00794, 833L643, C-54162, SR-01000002971-2, SR-01000002971-6, SR-01000002971-9, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, Succinate, Loxapine succinate, United States Pharmacopeia (USP) Reference Standard, (E)-2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine succinate, 2-Chloro-11-(4-methyl-1- piperazinyl)-dibenz[b,f][1,4]- oxazepine succinate, butanedioic acid; 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine butanedioic acid

ID: 2745

chemical graph of compound 2745



InChIKey: YRCWQPVGYLYSOX-UHFFFAOYSA-N
SMILES: CNCC(C1=CC=C(C=C1)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 7172
synonyms found at PubChem are:
Synephrine, Oxedrine, p-Synephrine, 94-07-5, Parasympatol, Sympaethamine, Sympatol, Sympaethamin, Analeptin, Simpatol, Simpalon, Synephrin, Synthenate, (+/-)-Synephrine, Sympathol, p-Oxedrine, 4-(1-Hydroxy-2-(methylamino)ethyl)phenol, Ethaphene, DL-SYNEPHRINE, Synefrin, 4-[1-Hydroxy-2-(methylamino)ethyl]phenol, Synefrin [Czech], Pentedrin [German], Parakorper [German], p-Methylaminoethanolphenol, 1-(4-Hydroxyphenyl)-N-methylethanolamine, 1-(4-Hydroxyphenyl)-2-methylaminoethanol, Oxedrine [BAN], NSC 166285, p-Hydroxyphenylmethylaminoethanol, CHEBI:29081, S 38537-9, EINECS 202-300-9, beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol, Methylaminomethyl(4-hydroxyphenyl)carbinol, 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol, YRCWQPVGYLYSOX-UHFFFAOYSA-N, (RS)-1-(4-Hydroxyphenyl)-2-(methylamino)ethanol, Oxedrine (BAN), p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol, 4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol, NSC166285, 582-84-3, Benzenemethanol, 4-hydroxy-.alpha.-[(methylamino)methyl]-, alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan [German], 1-(4-Hydroxyphenyl)-(2-methylamino)ethanol, BENZYL ALCOHOL, p-HYDROXY-alpha-((METHYLAMINO)METHYL)-, (-)-, WLN: QR DYQ1M1, Oxedrine hydrochloride, DSSTox_CID_10588, DSSTox_RID_78850, 4-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol, DSSTox_GSID_30588, p-Hydroxy-alpha-[(methylamino)methyl]benzyl alcohol, 4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol, l-Synephrine, Q-100668, W-100214, l-Sympatol, p-((Methylamino)ethanol)phenol, p-[(Methylamino)ethanol]phenol, p-Hydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol, .beta.-Methylamino-.alpha.-(4-hydroxyphenyl)ethyl alcohol, Benzyl alcohol, p-hydroxy-.alpha.-[(methylamino)methyl]-, Parakorper, BENZYL ALCOHOL, p-HYDROXY-alpha-((METHYLAMINO)METHYL)-, p-Hydroxyphenyl(methylamino)ethanol, ( )-Synephrine, Oxedrine ((-)-), 1-[4-Hydroxyphenyl]-2-methylaminoethanol, SMR000059111, 1-(4-Hydroxyphenyl)-(N-methylethanol)amine, 1-(4-hydroxyphenyl)-2-(methylamino)ethan-1-ol, Oxedrine [INN:BAN], ((Methylamino)methyl)((4-hydroxyphenyl)carbinol), [(Methylamino)methyl][(4-hydroxyphenyl)carbinol], SR-01000002983, p-Hydroxy-.alpha.-[(methylamino)methyl]benzylalcohol, (+-)-N-Methyloctopamine, Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-, (S)-, oxedrine HCl, (y)-Synephrine, Synephrine,(S), CAS-94-07-5, NCGC00016351-01, (?)-Synephrine, (+/-)synephrine, (+,-)-Synephrine, NSC 170956, Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-, Synephrine (Oxedrine), Synephrine - Oxedrine, Prestwick0_001088, Prestwick1_001088, Prestwick2_001088, Prestwick3_001088, (.+/-.)-Synephrine, Lopac0_001085, BSPBio_001136, alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan, MLS000069435, MLS001424216, CHEMBL33720, SCHEMBL146500, SPBio_003028, BENZYL ALCOHOL, p-HYDROXY-alpha-((METHYLAMINO)METHYL)-, (+)-, Synephrine, analytical standard, (.+/-.)-N-Methyloctopamine, AC1L1O67, AC1Q412W, BPBio1_001250, DTXSID0030588, CTK2F4574, MolPort-000-787-358, (+/-)-Synephrine, >=98%, HMS1571I18, HMS2052G09, HMS2098I18, HMS2233F20, HMS3263I12, HMS3264E11, HMS3369C13, HMS3394G09, HMS3656O09, HMS3715I18, Pharmakon1600-01506085, ALBB-025740, ZX-AN024253, Tox21_110390, Tox21_200962, Tox21_501085, ( inverted question mark)-Synephrine, BBL015111, BDBM50102660, CS0043, NSC170956, NSC759316, PDSP1_000167, PDSP2_000166, s2362, SBB063601, STK803113, AKOS004119915, AKOS016038542, Tox21_110390_1, API0024621, CCG-101098, CCG-205162, DB09203, FCH1116446, KS-5152, LP01085, MCULE-4991429316, NC00348, NSC-166285, NSC-170956, NSC-759316, RP23020, ( inverted exclamation markA)-Synephrine, NCGC00015924-03, NCGC00015924-04, NCGC00015924-05, NCGC00015924-06, NCGC00015924-08, NCGC00015924-09, NCGC00015924-12, NCGC00015924-13, NCGC00089788-02, NCGC00089788-03, NCGC00089788-04, NCGC00258515-01, NCGC00261770-01, (+)-[(methylamino)methyl]-Benzenemethano, AK141733, BP-12742, CC-34623, CPD000059111, K712, LS-43028, LS-43029, LS-43031, SAM001246896, SC-46736, ST095769, SBI-0051055.P002, AB0014348, AX8011379, TR-038493, AB00514040, EU-0101085, FT-0618685, FT-0653012, N1706, S0232, T5534, 4-[1-Hydroxy-2-(methylamino)ethyl]phenol #, 4-Hydroxy-a-(methylaminomethyl)benzyl alcohol, 94S075, C04548, D07148, S 0752, AB00384265_11, C-33457, I01-2279, I01-8196, I06-0007, SR-01000002983-3, SR-01000002983-7, SR-01000002983-8, 4-Hydroxy-.alpha.-((methylamino)methyl)benzenemethanol, 7336264B-EDC9-42C5-939B-FF800AB5BB4A, Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)- (9CI), Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-, (-)-, Oxedrine|||4-Hydroxy-a-[(methylamino)methyl]-benzenemethanol, Oxedrine, p-Synephrine, Sympatol, Parasympatol, Sympaethamine, 34520, benzenemethanol, 4-hydroxy-alpha-[(methylamino)methyl]-, 2,3-dihydroxybutanedioate (1:1) (salt)

ID: 2746

chemical graph of compound 2746



InChIKey: YRRYHMLYGVNPBW-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CCSC(=N)N)CCSC(=N)N.Br.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957667
synonyms found at PubChem are:
1,4-PB-ITU dihydrobromide, 1,4-PBIT dihydrobromide, 157254-60-9, SR-01000076085, EU-0100983, C12H18N4S2.2HBr, SCHEMBL2283156, CHEMBL1451880, CTK8E9434, DTXSID70474698, MolPort-039-138-838, 1127AH, AKOS015910211, LP00983, NCGC00094283-01, RT-005884, FT-0643537, P 8352, 1,4-Phenylene-bis(1,2-ethanediyl)bis-isothiourea, C-42304, J-009398, SR-01000076085-1, SR-01000076085-5, I14-40866, 2,2'-(1,4-phenylene)bis(ethane-2,1-diyl) dicarbamimidothioate dihydrobromide

ID: 2747

chemical graph of compound 2747



InChIKey: YRWLZFXJFBZBEY-UHFFFAOYSA-N
SMILES: CCCCC1=CC2=C(C=C1)N=C(N2)NC(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 26596
synonyms found at PubChem are:
Parbendazole, 14255-87-9, Helmatac, Worm Guard, Verminum, Helatac, PBDZ, Methyl (5-butyl-1H-benzo[d]imidazol-2-yl)carbamate, SKF 29044, UNII-N4X8WVX2UG, Parbendazol [INN-Spanish], Parbendazolum [INN-Latin], METHYL 5-BUTYL-2-BENZIMIDAZOLECARBAMATE, SK&F 29044, Carbamic acid, (5-butyl-1H-benzimidazol-2-yl)-, methyl ester, 5-Butyl-2-(carbomethoxyamino)benzimidazole, TCMDC-131798, EINECS 238-133-3, SKF-29044, N4X8WVX2UG, 5-Butyl-2-benzimidazolecarbamic acid methyl ester, methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate, 2-Benzimidazolecarbamic acid, 5-butyl-, methyl ester, NCGC00016706-01, (4-Butyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester, N-(Butyl-5, benzimidazolyl)-2, carbamate de methyle [French], CAS-14255-87-9, Methyl 5(6)-butyl-2-benzimidazolecarbamate, DSSTox_CID_25410, DSSTox_RID_80861, DSSTox_GSID_45410, Methyl 5-butyl-1H-benzo[d]imidazol-2-ylcarbamate, Parbendazol, Parbendazolum, C13H17N3O2, Parbendazole [USAN:BAN:INN], Parbendazole [USAN:INN:BAN], Prestwick0_001110, Prestwick1_001110, Prestwick2_001110, Prestwick3_001110, Parbendazole (USAN/INN), AC1L1BH3, BSPBio_001220, SCHEMBL259455, SPBio_003090, BPBio1_001342, CHEMBL528271, N-(Butyl-5, benzimidazolyl)-2, carbamate de methyle, DTXSID0045410, CHEBI:94267, KS-00000GVU, MolPort-003-986-418, HMS1571M22, HMS2098M22, HMS3715M22, ZINC5424253, Tox21_110571, NSC256420, WLN: T56 BM DNJ CMVO1 G4, AKOS015898352, AKOS015967508, Tox21_110571_1, 2H-Benzimidazole, carbamic acid deriv., AC-1936, CCG-221110, NSC-256420, SK&F-29044, Methyl 5-butylbenzimidazole-2-carbamate, NCGC00016706-02, NCGC00016706-03, NCGC00016706-04, NCGC00016706-05, NCGC00016706-07, AJ-54021, AJ-54022, AK121902, AN-14473, BC220775, KB-59429, LS-32693, OR305450, SC-79806, 2-carbomethoxyamino-5-n-butylbenzimidazole, AB0001013, AX8146768, HY-115364, TL8000939, AB00514054, CS-0035171, FT-0630413, methyl 5-butyl-1H-benzimidazol-2-ylcarbamate, D05365, Z-3080, Methyl (5-butyl-1H-benzimidazol-2-yl)carbamate, Methyl (5-butyl-1H-benzoimidazol-2-yl)carbamate, Parbendazole, VETRANAL(TM), analytical standard, 255P879, methyl N-(5-butyl-1H-benzimidazol-2-yl)carbamate, SR-01000872691, (5-Butyl-2-benzimidazole)carbamic acid methyl ester, I10-0671, Methyl(5-butyl-1H-benzo[d]imidazol-2-yl)carbamate, SR-01000872691-1, BRD-K02407574-001-03-0, BRD-K02407574-001-04-8, BRD-K02407574-001-06-3, Parbendazole, United States Pharmacopeia (USP) Reference Standard, 52980-90-2

ID: 2748

chemical graph of compound 2748



InChIKey: YSEXMKHXIOCEJA-FVFQAYNVSA-N
SMILES: CN1C[C@@H](C[C@]2([C@H]1CC3=CN(C4=CC=CC2=C34)C)OC)COC(=O)C5=CC(=CN=C5)Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 34040
synonyms found at PubChem are:
nicergoline, 27848-84-6, Nicotergoline, Nimergoline, Nimergoline base, Nicergolinum, Nicergolin, Nicergolina, Sermion, Nicergolin [German], Nicergolina [DCIT], Nicergolinum [INN-Latin], Nargoline, Nicergoline [USAN:BAN:INN:JAN], UNII-JCV8365FWN, C24H26BrN3O3, Sermion (TN), FI 6714, RP 19651, EINECS 248-694-6, NSC 150531, BRN 4828393, JCV8365FWN, 1-Methyl-lumilysergol 8-(5-bromonicotinate) 10-methyl ether, CHEBI:31902, 10-Methoxy-1,6-dimethylergoline-8beta-methanol 5-bromonicotinate, (+)-10-Methoxy-1,6-dimethylergoline-8-beta-methanol 5-bromonicotinate, 10-Methoxy-1,6-dimethylergoline-8beta-methanol 5-bromonicotinate (ester), 10-Methoxy-1,6-dimethyl-ergolin-8-beta-methanol-(5-bromnicotinat) [German], 8-beta-((5-Bromonicotinoyloxy)methyl)-1,6-dimethyl-10-alpha-methoxyergoline, 10-Methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyrindinecarboxylate (ester), Ergoline-8-beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), NCGC00017259-04, 10-Methoxy-1,6-dimethyl-ergolin-8-beta-methanol-(5-bromnicotinat), 5-Bromonicotinic acid 10-methoxy-1,6-dimethylergoline-8-methyl ester, Ergoline-8-beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester), Ergoline-8beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester), DSSTox_CID_25607, DSSTox_RID_81000, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8beta)-, 5-bromo-3-pyridinecarboxylate (ester), Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8beta)-, DSSTox_GSID_45607, MNE, [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl 5-Bromopyridine-3-carboxylate, ((6AR,9R,10AS)-10A-METHOXY-4,7-DIMETHYL-4,6,6A,7,8,9,10,10A-OCTAHYDROINDOLO[4,3-FG]QUINOLIN-9-YL)METHYL 5-BROMONICOTINATE, CAS-27848-84-6, SR-01000597616, cergodum, duracebrol, nicergolent, Nicergoline,(S), [(6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl]methyl 5-bromopyridine-3-carboxylate, Nicergoline [USAN:INN:BAN:JAN], Spectrum_001370, F.I. 6714, Prestwick0_000147, Prestwick1_000147, Prestwick2_000147, Prestwick3_000147, Spectrum2_001414, Spectrum3_001933, Spectrum4_000440, Spectrum5_001352, D0V2GH, AC1L1QT0, SCHEMBL22964, BSPBio_000254, BSPBio_003533, KBioGR_000800, KBioSS_001850, DivK1c_000124, SPECTRUM1501133, SPBio_001488, SPBio_002193, BPBio1_000280, CHEMBL1372950, DTXSID7045607, HMS500G06, KBio1_000124, KBio2_001850, KBio2_004418, KBio2_006986, KBio3_002787, Nicergoline (JP15/USAN/INN), Nicergoline (JP17/USAN/INN), MolPort-002-513-778, NINDS_000124, YSEXMKHXIOCEJA-FVFQAYNVSA-N, HMS1568M16, HMS1923O09, HMS2089I03, HMS2092F07, HMS2095M16, HMS3712M16, Pharmakon1600-01501133, HY-B0702, ZINC3873817, Tox21_110810, CCG-39032, MFCD00869626, NSC757853, AKOS005067888, AKOS015969107, Tox21_110810_1, AB07582, API0003559, CS-2941, DB00699, Nicergoline 1.0 mg/ml in Acetonitrile, NSC-757853, IDI1_000124, QTL1_000060, NCGC00017259-03, NCGC00017259-05, NCGC00017259-07, NCGC00024678-02, NCGC00024678-03, AJ-46381, AK-77489, AS-12239, CC-32827, LS-64447, ST055762, SBI-0051652.P002, AB0011579, AX8041546, N0904, ST24048789, D01290, AB00052214-04, AB00052214_05, 848N846, C-22831, SR-05000001751, I06-1875, J-016896, Nicergoline, analytical standard, for drug analysis, SR-01000597616-1, SR-01000597616-2, SR-05000001751-1, BRD-K76810206-001-05-7, BRD-K76810206-001-06-5, Nicergoline, European Pharmacopoeia (EP) Reference Standard, Ergoline-8beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester) (8CI), Nicergoline for peak identification, European Pharmacopoeia (EP) Reference Standard, Nicergoline for system suitability, European Pharmacopoeia (EP) Reference Standard, (8BETA)-10-METHOXY-1,6-DIMETHYLERGOLINE-8-METHANOL 5-BROMO-3-PYRIDINE CARBOXYLATE ESTER, [(2S,4R,7R)-2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0;{2,7}.0;{12,16}]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl 5-bromopyridine-3-carboxylate, 5-BROMO-NICOTINIC ACID (6AR,9R,10AS)-10A-METHOXY-4,7-DIMETHYL-4,6,6A,7,8,9,10,10A-OCTAHYDRO-INDOLO[4,3-FG]QUINOLIN-9-YLMETHYL ESTER, 5-Bromopyridine-3-carboxylic Acid [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl Ester

ID: 2749

chemical graph of compound 2749



InChIKey: YSUCWSWKRIOILX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CCN=C(N)N=C(N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 13266
synonyms found at PubChem are:
PHENFORMIN HYDROCHLORIDE, 834-28-6, Phenformin HCl, Meltrol, Dipar, Phenethylbiguanide hydrochloride, Meltrol-50, Phenformin.HCl, USAF VI-6, 1-Phenethylbiguanide hydrochloride, DBI-TD, Phenformin, hydrochloride, Phenformin (hydrochloride), Phenethylbiguanide hydrochloride (VAN), Phenformin HCl No. 9113, UNII-91XC93EU03, Biguanide, 1-phenethyl-, hydrochloride, CCRIS 4857, 1-(2-Phenylethyl)biguanide hydrochloride, Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride, EINECS 212-637-3, NSC 23100, 1beta-Phenylethylbiguanide hydrochloride, 1-Fenetilbiguanide cloridrato [Italian], N'-beta-Phenethylbiguanide hydrochloride, N-Phenethylbiguanide hydrochloride (VAN), C10H15N5.HCl, N'-beta-Phenylethylbiguanide-hydrochloride, N-beta-Phenylethyl biguanide hydrochloride, Biguanide, 1-phenethyl-, monohydrochloride, AI3-51271, MLS000028506, 1-Phenylaethylbiguanid hydrochlorid [German], N(sup 1)-beta-Phenethylbiguanide hydrochloride, 91XC93EU03, 1-phenethyl-biguanidmonohydrochloride, NCGC00091940-01, SMR000058276, DSSTox_CID_1121, DSSTox_RID_75952, DSSTox_GSID_21121, W-104144, 1-(diaminomethylene)-2-(2-phenylethyl)guanidine hydrochloride, 1-Carbamimidamido-N-(2-phenylethyl)methanimidamide hydrochloride, N-(2-phenylethyl)imidodicarbonimidic diamide hydrochloride, Phenformini Hydrochloride, NCGC00016543-01, CAS-834-28-6, 1-carbamimidoyl-3-(2-phenylethyl)guanidine;hydrochloride, 1-Fenetilbiguanide cloridrato, Phenformin hydrochloride [USP], SR-05000001790, 1-Phenylaethylbiguanid hydrochlorid, Prestwick_615, Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride, Debei (TN), Opera_ID_374, MLS001148130, MLS002154228, SCHEMBL210008, AC1L21E0, WLN: MUYZMYUM&M2R &GH, CHEMBL1528839, DTXSID0021121, CTK2G5282, KS-00000GWG, MolPort-000-715-918, YSUCWSWKRIOILX-UHFFFAOYSA-N, HMS1568D19, Pharmakon1600-01505983, BCP21997, NSC23100, Tox21_110484, Tox21_111185, Tox21_202197, Tox21_303004, HY-16397A, KM2166, NSC-23100, NSC751918, NSC759903, s2542, 1-phenethylbiguanide monohydrochloride, AKOS015895377, Tox21_111185_1, AC-5631, AN-5862, API0025906, CCG-213589, CCG-230656, CS-1850, LS-1832, MCULE-2649903903, NSC-751918, NSC-759903, .alpha.-Phenethylbiguanide hydrochloride, NCGC00016543-07, NCGC00164394-01, NCGC00180985-01, NCGC00256332-01, NCGC00259746-01, 1.beta.-Phenylethylbiguanide hydrochloride, AS-10997, SC-22718, N'-.beta.-Phenethylbiguanide hydrochloride, AB0008519, AB2000639, FT-0603518, N'-.beta.-Phenylethylbiguanide-hydrochloride, Phenformin hydrochloride, analytical standard, ST50409947, 34P286, D08352, N(sup 1)-beta- phenethylbiguanide hydrochloride, 2-(N-phenethylcarbamimidoyl)guanidine hydrochloride, C-14530, I06-0620, SR-05000001790-2, 1-(diaminomethylidene)-2-phenethylguanidine hydrochloride, amino{imino[(2-phenylethyl)amino]methyl}carboxamidine, chloride, PHENFORMIN HYDROCHLORIDE (SEEALSO PHENFORMIN 114-86-3), Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1), Phenformin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 21228-47-7, 78445-32-6, AKOS026750110

ID: 2750

chemical graph of compound 2750



InChIKey: YSVYWVPJJXVIFM-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5702250
synonyms found at PubChem are:
DL-Stearoylcarnitine chloride, STEAROYLCARNITINE CHLORIDE, S-7947, 18822-91-8, 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[(1-oxooctadecyl)oxy]-, chloride (1:1), AC1NWAWY, Stearoyl-DL-carnitine chloride, SCHEMBL1321243, CHEMBL1476762, HMS503K15, YSVYWVPJJXVIFM-UHFFFAOYSA-N, HMS3263O14, Tox21_501116, AKOS015914578, LP01116, NCGC00094386-01, NCGC00261801-01, EU-0101116, S 2381, SR-01000076124, SR-01000076124-2, I14-40996, (4-hydroxy-2-octadecanoyloxy-4-oxobutyl)-trimethylazanium chloride

ID: 2751

chemical graph of compound 2751



InChIKey: YTFVRYKNXDADBI-SNAWJCMRSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 735755
synonyms found at PubChem are:
3,4,5-TRIMETHOXYCINNAMIC ACID, 90-50-6, O-Methylsinapic acid, 20329-98-0, 3,4,5-Trimethoxyphenylacrylic acid, 3-(3,4,5-trimethoxyphenyl)acrylic acid, NSC 66175, 3-(3,4,5-Trimethoxyphenyl)-2-propenoic acid, 3,4,5-Trimethoxy cinnamic acid, (E)-3-(3,4,5-trimethoxyphenyl)acrylic acid, SINAPIC ACID METHYL ETHER, Cinnamic acid, 3,4,5-trimethoxy-, EINECS 201-999-8, (2E)-3-(3,4,5-trimethoxyphenyl)acrylic acid, 3,4,5-Trimethoxy-trans-cinnamic acid, (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoic acid, BRN 1537834, (2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoic acid, 2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, (2E)-, UNII-C9096D920O, YTFVRYKNXDADBI-SNAWJCMRSA-N, NSC66175, NSC-66175, 2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, C9096D920O, W-100329, 3,4,5-Trimethoxycinnamate, SMR000371917, CHEBI:566519, O-Methylsinapate, o-methylsinapicacid, trans-3,4,5-Trimethoxycinnamic acid, PubChem8300, AC1LEGKZ, rarechem bk hc t328, AC1Q5RAK, Spectrum5_000448, bmse010224, AC1Q5T8W, 3,5-Trimethoxycinnamic acid, 3,4,5-Trimethoxy cinnamate, BSPBio_002796, SPECTRUM290032, 2-10-00-00354 (Beilstein Handbook Reference), MLS000757621, MLS002207275, SCHEMBL207441, 3,4,5-trimethoxy-cinnamicaci, CHEMBL501235, Cinnamic acid,4,5-trimethoxy-, 3,4,5-Trimethoxyphenylacrylate, otava-bb bb7119152925, DTXSID7059010, 3,4,5-trimethoxyphenylacrylicacid, MolPort-000-685-197, MolPort-004-288-326, BDBM232204, HMS2232E22, ZINC152561, 3, 4, 5-Trimethoxycinnamic Acid, ALBB-007558, BB_NC-00387, ZX-AN007080, ZX-AT009367, 3,4,5-Trimethoxybenzeneacrylic acid, BBL011951, CCG-39479, CT-191, HTS001488, KM2928, OR6576, SBB038595, STK500969, AKOS000120453, 3,4,5-Trimethoxycinnamic acid, 97%, BS-4465, CS-W012839, MCULE-8351376607, RP09331, RTR-030993, SDCCGMLS-0066950.P001, 3,4,5-Trimethoxycinnamic acid (TMCA), NCGC00095563-01, NCGC00095563-02, 2-Propenoic acid,4,5-trimethoxyphenyl)-, AC-16693, AC-24565, AJ-12757, AK-43306, AN-42525, AS-11999, LS-54183, SC-07259, 3-(3,4,5-Trimethoxyphenyl)propenoic acid, AB1000948, BC2197781, Cinnamic acid, 3,4,5-trimethoxy-, (E)-, KB-177506, RT-002812, TR-030993, 3,4,5-Trimethoxycinnamic acid, pred. trans, 3-(3,4,5-trimethoxyphenyl)-2-propenoicaci, 3-(3,5-Trimethoxyphenyl)-2-propenoic acid, ST24032529, ST45027564, 3-(3,4,5-trimethoxyphenyl)-2-propenoicacid, (E)-3-(3,4,5-trimethoxyphenyl) acrylic acid, (e)-3-(3,4,5-trimethoxy-phenyl)-acrylic acid, 004T388, AS-871/13102032, SR-01000773278, SR-01000773278-2, BRD-K63758740-001-02-3, 2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, (E)-, 2-Propenoic acid,3-(3,4,5-trimethoxyphenyl)-, (2E)-, F3284-8534, 646E4CC1-F441-40D8-B1BB-87A43D1B3600, 3,4,5-Trimethoxycinnamic acid, analytical reference material

ID: 2752

chemical graph of compound 2752



InChIKey: YTNKWDJILNVLGX-UHFFFAOYSA-N
SMILES: CN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 71764
synonyms found at PubChem are:
Alfuzosin Hydrochloride, 81403-68-1, Uroxatral, Alfuzosin HCl, Xatral, Urion, Alfoten, Alfetim, Xatral Retard, Alfuzosin (hydrochloride), Xatral OD, Xatral SR, Xatral XL, Uroxatral (TN), Alfuzosin hydrochloride [USAN], SL 77499-10, SL 77 499-10, SL-7749910, Alfuzosin hydrochloride (Uroxatral), Alfuzosin hydrochloride (JAN/USAN), (+-)-N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furamide monohydrochloride, SL-77499, SL-77499-10, SL-77.0499-10, DSSTox_CID_25514, DSSTox_RID_80924, DSSTox_GSID_45514, n-{3-[(4-amino-6,7-dimethoxychinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamidhydrochlorid, CHEBI:32286, 2-Furancarboxamide, N-(3-((4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-, monohydrochloride (+-)-, N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide hydrochloride, N-[3-[4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride, C19H27N5O4, N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride, N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl), SR-01000759345, N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, n-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride, Alfuzosin hydrochloride [USAN:USP], Uroxatral hydrochloride, Alfuzosin hydrochloride;, AC1L2GRP, AC1Q5PED, NCGC00016946-01, D0H1YQ, SL77.0499-10, CAS-81403-68-1, Alfuzosin Hydrochloride,(S), CHEMBL1723, C19H28ClN5O4, SCHEMBL179910, DTXSID3045514, CTK8F7637, HY-B0192A, MolPort-006-391-851, Uroxatral, Alfuzosin hydrochloride, YTNKWDJILNVLGX-UHFFFAOYSA-N, BCPP000417, HMS1569A05, 81403-80-7 (Parent), KS-00000XK8, Tox21_110701, Tox21_500224, MFCD00879135, s1409, (methyl)amino)propyl)tetrahydrofuran-2, AKOS015966770, Tox21_110701_1, AC-1116, API0001407, BCP9000271, CCG-213373, CS-2087, LP00224, NCGC00095152-09, NCGC00260909-01, AS-14240, AT-12271, BC677639, CC-23835, K448, LS-70107, AB0008072, AB2000094, A2591, FT-0630890, D01692, Alfuzosin hydrochloride, >=98% (HPLC), solid, 403A681, SR-01000759345-5, Alfuzosin hydrochloride, European Pharmacopoeia (EP) Reference Standard, Alfuzosin hydrochloride, United States Pharmacopeia (USP) Reference Standard, Alfuzosin for peak identification, European Pharmacopoeia (EP) Reference Standard, Alfuzosin for system suitability A, European Pharmacopoeia (EP) Reference Standard, Alfuzosin for system suitability, European Pharmacopoeia (EP) Reference Standard, Alfuzosin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 133880-44-1, 4-Amino-6,7-dimethoxy-2-[methyl[3-[(tetrahydro-2-furoyl)amino]propyl]amino]quinazoline Hydrochloride, N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)(methyl)amino]propyl]tetrahydro-2-furancarboxamide Hydrochloride, N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolynyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride, N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide hydrochloride, AKOS026749786

ID: 2753

chemical graph of compound 2753



InChIKey: YUFRRMZSSPQMOS-UHFFFAOYSA-N
SMILES: C(CSSCCN)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5941
synonyms found at PubChem are:
Cystamine dihydrochloride, 56-17-7, 2,2'-Disulfanediyldiethanamine dihydrochloride, Cystamin dihydrochloride, Ethanamine, 2,2'-dithiobis-, dihydrochloride, USAF CB-34, 2-Aminoethyl disulfide dihydrochloride, Bis(2-aminoethyl) disulfide dihydrochloride, Cystamine 2HCL, UNII-I90T518457, EINECS 200-260-7, NSC 39322, 2,2'-Dithiodi(ethylammonium) dichloride, Decarboxycystine dihydrochloride, 2,2'-Dithio-bis-(ethylamine) dihydrochloride, Usafcb-34, 2-Aminoethyl Dislufide Dihydrochloride, {2-[(2-aminoethyl)disulfanyl]ethyl}amine dihydrochloride, I90T518457, 2,2'-Diaminodiethyl disulfide dihydrochloride, C-9450, 2-(2-aminoethyldisulfanyl)ethanamine dihydrochloride, ETHYLAMINE, 2,2'-DITHIOBIS-, DIHYDROCHLORIDE, 2-[(2-aminoethyl)disulfanyl]ethan-1-amine dihydrochloride, 51-85-4 (Parent), Cystamine HCl, 111625-30-0, di2-aminoethyl disulfide, chloride, chloride, Cystaminedihydrochloride, 2,2'-Dithiobis(ethylamine) dihydrochloride, Cystamine DiHCl, cystamine-di-hcl, cystamine dihydrocloride, cystamine dihyrochloride, AC1L1LGR, AC1Q3AVW, cystamine bis-hydrochloride, D0WI3W, ACMC-1B12F, C4H12N2S2.2HCl, SCHEMBL320311, SPECTRUM1503821, AC1Q3B76, ARONIS014392, Cystamine dihydrochloride, 96%, CHEMBL1594935, DTXSID6058766, CTK7E9525, BBC/119, Cystamine dihydrochloride, BioXtra, MolPort-002-320-854, YUFRRMZSSPQMOS-UHFFFAOYSA-N, HMS1922I14, ZX-AS004339, Tox21_500297, ANW-32460, CCG-39369, MFCD00012905, SBB003325, AKOS005111080, API0002170, GS-3569, LP00297, RTR-032041, TRA0101345, 2,2-DITHIOBIS(ETHYLAMINE)DI HCl, KS-000009I6, KS-000044U7, BIS(2-AMINOETHYL)DISULFIDE di HCl, NCGC00093747-01, NCGC00093747-02, NCGC00093747-03, NCGC00260982-01, AK-47593, BC201501, BP-30235, BR-47593, KB-76367, LS-68221, SC-62201, SY012856, 2,2'-Dithiobis(Ethylamine)Dihydrochloride, 2,2-Dithiobis(Ethylamine) Dihydrochloride, AB0010624, AX8123147, DB-052857, KB-220713, ST2412772, TR-032041, 2,2'-Dithio-Bis-(Ethylamine)Dihydrochloride, AM20100373, C0875, EU-0100297, FT-0624311, ST45051085, C 7255, M-6458, 012C905, C-36402, Cystamine dihydrochloride, purum, >=98.0% (AT), SR-01000075778, Ethanamine, 2,2'-dithiobis-, hydrochloride (1:2), SR-01000075778-1, I14-13918, Cystamine dihydrochloride, PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production., MolPort-000-778-338, MCULE-3814449504, AKOS025117325, Cystamine dihydrochloride, 97% 25g, {2-[(2-aminoethyl)dithio]ethyl}amine dihydrochloride

ID: 2754

chemical graph of compound 2754



InChIKey: YUSWMAULDXZHPY-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281600
synonyms found at PubChem are:
Amentoflavone, 1617-53-4, 3',8''-Biapigenin, Didemethyl-ginkgetin, Amenthoflavone, UNII-9I1VC79L77, CHEMBL63354, MLS000574827, CHEBI:2631, 9I1VC79L77, SMR000156235, Q-100192, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, 8-[5-(5,7-dihydroxy-4-oxo-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one, Tridemethylsciadopitysin, SR-01000721725, NSC 295677, AC1NQYPA, D06HRX, BIDD:PXR0028, SCHEMBL312563, MEGxp0_000924, cid_5281600, CTK8F7701, DTXSID20167225, Amentoflavone, analytical standard, MolPort-001-741-078, YUSWMAULDXZHPY-UHFFFAOYSA-N, HMS2228B12, HMS3343J17, BCP13255, HY-N0662, ZINC3984030, Amentoflavone, >=99.0% (HPLC), BDBM50129952, LMPK12040009, MFCD00017470, MFCD20275041, NSC295677, (4-hydroxyphenyl)-4H-chromen-4-one, AKOS015896819, CS-4945, NSC-295677, 3',8-Bi[4',5,7-trihydroxyflavone], NCGC00247542-01, AN-49542, CC-24050, SC-13592, FT-0622262, N2268, W1536, KS-00000037, C10018, 617A534, A810291, C-23136, 8-(5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2, I07-0160, SR-01000721725-2, SR-01000721725-3, 4',5,7-Trihydroxyflavone(3'->8)-4',5,7-trihydroxyflavone, 4',4''',5,5'',7,7''-Hexahydroxy-3''',8-biflavone, 8CI, 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,8'-bi-4H-1-benzopyran]-4,4'-dione, 2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-, 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl), 4H-1-Benzopyran-4-one,8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-, 8-[5-(5,7-dihydroxy-4-oxo-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one, 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one, 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one

ID: 2755

chemical graph of compound 2755



InChIKey: YUTIFCZVCWLLRH-UHFFFAOYSA-N
SMILES: CC1=CC=CC2=C1N=C(C(=C2)C#N)NCCNC(=O)C3=CC(=C(C=C3)OC)OC

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"MJ Kurth" "AB Wood" "PW Phuan" "GL Lukacs" "JM Knapp" "AS Verkman" "B Yang"


CID is 3217019
synonyms found at PubChem are:
606105-18-4, N-[2-(3-Cyano-8-methyl-quinolin-2-ylamino)-ethyl]-3,4-dimethoxy-benzamide, N-[2-[(3-cyano-8-methylquinolin-2-yl)amino]ethyl]-3,4-dimethoxybenzamide, N-{2-[(3-Cyano-8-methylquinolin-2-yl)amino]ethyl}-3,4-dimethoxybenzamide, AC1MLAR1, MLS001212849, CHEMBL1583913, SCHEMBL14235623, CTK5B1861, DTXSID80390436, HMS1684M07, HMS2838E04, ZINC4881259, AKOS000765246, MCULE-9320928985, ASN 06146799, SMR000503707, KB-301142, SR-01000341399, SR-01000341399-1, N-[2-[(3-cyano-8-methylquinolin-2-yl)amino]ethyl]-3,4-dimeth, N-{2-[(3-Cyano-8-methyl-2-quinolinyl)amino]ethyl}-3,4-dimethoxybenzamide, BENZAMIDE, N-[2-[(3-CYANO-8-METHYL-2-QUINOLINYL)AMINO]ETHYL]-3,4-DIMETHOXY-

ID: 2756

chemical graph of compound 2756



InChIKey: YVCVYCSAAZQOJI-JHQYFNNDSA-N
SMILES: COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 122797
synonyms found at PubChem are:
4'-Demethylepipodophyllotoxin, 6559-91-7, 4'-DMEP, 4-Demethylepipodophyllotoxin, UNII-X0S6I23X6L, (-)-4'-Demethylepipodophyllotoxin, BRN 1358259, 4'-Demethyl-epipodophyllotoxin, X0S6I23X6L, CHEBI:74422, C21H20O8, (5R,5aR,8aR,9S)-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5-alpha,5a-beta,8a-alpha,9-beta))-, Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-, 4'-O-demethylepipodophyllotoxin, etoposide aglycone, NCGC00161927-01, (5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, D03YCW, AC1L3V9U, DSSTox_CID_28668, DSSTox_RID_82938, DSSTox_GSID_48742, CHEMBL31929, 4'-demethyl epipodophyllotoxin, 4/'-Demethylepipodophyllotoxin, epi-4'-demethylpodophyllotoxin, SCHEMBL9885196, DTXSID7048742, 4'-demethyl-9-epipodophyllotoxin, Epipodophyllotoxin, 4'-demethyl-, MolPort-016-633-323, YVCVYCSAAZQOJI-JHQYFNNDSA-N, 4'-O-demethyl-4-epipodophyllotoxin, EX-A1205, ZINC5670074, ZX-AT011557, (-)-4'-demethyl-epipodophyllotoxin, Tox21_113196, AKOS015896348, AC-7468, ACN-029912, AN-6408, API0008256, CCG-208563, CS-1426, 4'-Demethyl epi-Podophyllotoxin (DMEP), AS-18736, HY-17435, LS-70855, SC-87273, CAS-6559-91-7, AB0028992, AB3000013, KB-308876, FT-0082692, FT-0618332, X1118, C-1183, C21185, C-28519, SR-05000002194, I06-2044, Q-100747, SR-05000002194-2, (10R,11R,15R,16S)-16-hydroxy-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one, (10R,11R,15R,16S)-16-hydroxy-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1,3(7),8-trien-12-one, (5R,5aR,8aR,9S)-5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one, (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one, (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, (5s,5ar,8ar,9r)-9-(3,5-Dimethoxy-4-Oxidanyl-Phenyl)-5-Oxidanyl-5a,6,8a,9-Tetrahydro-5h-[2]benzofuro[6,5-F][1,3]benzodioxol-8-One, 4'-DMEP|||(5S,5aR,8aR,9R)-5-Hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, 89O, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9beta))-, Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-

ID: 2757

chemical graph of compound 2757



InChIKey: YVGGHNCTFXOJCH-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)C(Cl)(Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3036
synonyms found at PubChem are:
Clofenotane, Chlorophenothane, p,p'-DDT, dichlorodiphenyltrichloroethane, Dicophane, 50-29-3, Chlorphenothan, Chlorphenotoxum, Parachlorocidum, Pentachlorin, 4,4'-DDT, Zerdane, Arkotine, Benzochloryl, Bovidermol, Estonate, Guesarol, Santobane, Agritan, Anofex, Deoval, Detoxan, Didigam, Didimac, Genitox, Gesafid, Gesarol, Ivoran, Ixodex, Kopsol, Neocid, Pentech, Rukseam, Chlorophenotoxum, Citox, Detox, Dykol, Gyron, DDT, Bosan Supra, Chlorophenothan, Penticidum, Dibovin, Mutoxan, Tafidex, Zeidane, Dodat, Hildit, Aavero-extra, PEB1, p,p'-Dichlorodiphenyltrichloroethane, Chlorphenotane, Chlofenotan, Clofenotan, Ppzeidan, Azotox, Chlorophenothanum, 4,4'-Dichlorodiphenyltrichloroethane, 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane, Trichlorobis(4-chlorophenyl)ethane, Clofenotane technique, Clofenotanum, Dibovan, Gesapon, Gesarex, Geusapon, Guesapon, Mutoxin, Penticide, Dedelo, Havero-extra, Neocidol (solid), OMS 16, Chlorophenothanum technicum, Detox (pesticide), Rcra waste number U061, D.D.T. technique, NCI-C00464, Neocid (VAN), 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane, 1,1-Bis(4-chlorophenyl)-2,2,2-trichloroethane, Azotox M 33, Caswell No. 308, p'-Zeidane [France], 2,2-Bis(p-chlorophenyl)-1,1,1-trichloroethane, Neocidol, solid, Tech ddt, DDT [BSI:ISO], 1-Chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene, Clofenotanum [INN-Latin], Clofenotano [INN-Spanish], DDT, p,p'-, NSC 8939, OMS 0016 [French], para,para'-DDT, ENT 1,506, CCRIS 194, DDT 50 WP, DDT and metabolites, Micro ddt 75, UNII-CIW5S16655, HSDB 200, Azotox M-33, Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-, 1,1'-(2,2,2-trichloroethylidene)bis[4-chlorobenzene], 1,1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane, Klorfenoton [Swedish Pharmacopoeia], EINECS 200-024-3, 1,1,1-Trichloro-2,2-di(4-chlorophenyl)-ethane, 1,1-Bis-(p-chlorophenyl)-2,2,2-trichloroethane, RCRA waste no. U061, EPA Pesticide Chemical Code 029201, 1,1,1-Trichloro-2,2-bis-(4'-chlorophenyl)ethane, 1,1,1-Trichlorobis(chlorophenyl)ethane, BRN 1882657, Ethane, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-, AI3-01506, Bis(p-chlorophenyl)-2,2,2-trichloroethane, Benzene, 1,1'-(2,2,2-trichloroethylidene)bis[4-chloro-, 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-chlorobenzene), alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichlorethane, CHEBI:16130, YVGGHNCTFXOJCH-UHFFFAOYSA-N, 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano, 2,2,2-Trichloro-1,1-bis(4-chlorophenyl)ethane, CIW5S16655, 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan, ENT-1506, Trichlorobis(4'-chlorophenyl)ethane, 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan, Clofenotane (INN), Clofenotane [INN], Dichlorodiphenyltrichloroethane (DDT), 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene), 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan [Dutch], 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan [German], 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano [Italian], 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano [Italian], NCGC00091071-01, 2,2,2-trichlorobis(4-chlorophenyl)ethane, alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichloroethane, DSSTox_CID_375, 1,1-Bis(p-chlorophenyl)-2,2,2-trichloroethane, DSSTox_RID_75551, 1,1,1-trichloro-2-2-bis(4-chlorophenyl)ethane, 1,1-bis(p-Chlorophenyl)-2,2,2-trichIoroethane, DSSTox_GSID_20375, R50, 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane solution, Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-, Clofenotano, Klorfenoton, p'-Zeidane, CAS-50-29-3, Dicophaner, 4,4'-DDT (1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane), 4-chloro-1-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene, pe ntech, micro ddt 75, 4,4-DDT, Dicophane, BAN, OMS 0016, p,p-DDT, Chlorophenothane [NF], Spectrum_001927, 4,4'-DDT solution, SpecPlus_000558, p,p'-Dichlorodiphenyltrichloroethane (DDT), Spectrum2_001233, Spectrum3_000859, Spectrum4_000699, Spectrum5_002036, p,p'-DDT, BSI, DDT(p,p'), bmse000634, SCHEMBL7181, 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano, BIDD:PXR0066, BSPBio_002477, Dichlorojiphinyltrichloroethane, KBioGR_001197, KBioSS_002469, SPECTRUM330070, WLN: GXGGYR DG&R DG, BIDD:ER0496, DivK1c_006654, SPBio_001106, AC1L1F12, CHEMBL416898, DTXSID4020375, 4,4|A-DDT, KBio1_001598, KBio2_002462, KBio2_005030, KBio2_007598, KBio3_001977, NSC8939, ACM50293, NSC-8939, ZINC1530011, 4,4 inverted exclamation marka-DDT, Tox21_111076, Tox21_201495, Tox21_300067, BDBM50410508, CCG-39114, LS-138, MFCD00000802, SBB061567, .alpha.,.beta.,.beta.-trichlorethane, AKOS003235691, Tox21_111076_1, MCULE-1446144401, NCGC00091071-02, NCGC00091071-03, NCGC00091071-04, NCGC00091071-05, NCGC00091071-06, NCGC00091071-07, NCGC00091071-08, NCGC00254176-01, NCGC00259046-01, Trichloro-2,2-bis(p-chlorophenyl)ethane, 4,4'-DDT 10 microg/mL in Cyclohexane, AC-12071, AJ-26640, CC-25919, CJ-23947, 4,4'-DDT 100 microg/mL in Cyclohexane, 4,4'-DDT, 98%, p,p'-Dichlorodiphenyltrichloromethylmethane, 2,2,2-trichlorobis(4-chloroph enyl)ethane, TR-017982, 4,4 inverted exclamation marka-DDT solution, Bis(p-chlorophenyl)-2,2,2-trichloroetha ne, FT-0603206, ST51047572, T0379, 1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane, 1,1-Trichloro-2,2-di(4-chlorophenyl)ethane, 1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano, 4,4'-DDT solution 100 ng/muL in methanol, 1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan, 4,4'-DDT, PESTANAL(R), analytical standard, C04623, D07367, 1,1,1-Trichloro-2,2-di(4-chlorophenyl)ethane, 1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan, Ethane,1,1-trichloro-2,2-bis(4-chlorophenyl)-, Ethane,1,1-trichloro-2,2-bis(p-chlorophenyl)-, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane, 2,2,2-Trichloro-1,1-bis(p-chlorophenyl)-Ethane, C-20741, SR-01000883717, SR-01000883717-1, 1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane, Benzene,1'-(2,2,2-trichloroethylidene)bis[4-chloro-, BRD-K51799616-001-02-2, I14-19023, 1,1'-(2,2,2,-Trichloroethylidene)bis[4-chlorobenzene], 1,1'-(2,2,2-Trichloroethylidene)bis(4-chloro)-Benzene, 4,4'-DDT, certified reference material, TraceCERT(R), Benzene, 1,1'(2,2,2-trichloroethylidene)bis[4-chloro-, 1,1,1-TRICHLORO-2,2-BIS(PARA-CHLOROPHNYL)ETHANE, 1,1,1-Trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), 4,4'-(2,2,2-Trichloroethane-1,1-diyl)bis(chlorobenzene), 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene), 9CI, 1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane chlorophenothane, p,p'-DDT~p,p' -Dichloro-1,1-diphenyl-2,2,2-trichloroethane, p,p'-DDT~p,p'-Dichloro-1,1-diphenyl-2,2,2-trichloroethane, 1-Chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene #, 4,4'-DDT solution, 200 mug/mL in isooctane, analytical standard, .alpha.,.alpha.-Bis(p-chlorophenyl)-.beta.,.beta.,.beta.-trichlorethane, 1-Chloranyl-4-[2,2,2-Tris(Chloranyl)-1-(4-Chlorophenyl)ethyl]benzene, 4,4'-DDT solution, certified reference material, 5000 mug/mL in methanol, 4,4'-DDT solution, 100 ng/muL in methanol, PESTANAL(R), analytical standard, 1081843-15-3, 6WT, InChI=1/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13

ID: 2758

chemical graph of compound 2758



InChIKey: YVNAYSHNIILOJS-UHFFFAOYSA-N
SMILES: CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 64646
synonyms found at PubChem are:
6398-98-7, Amodiaquin dihydrochloride dihydrate, Amodiaquine dihydrochloride dihydrate, Amodiaquine HCl, Amodiaquine hydrochloride, UNII-K6PW2S574L, Amodiaquin (dihydrochloride dihydrate), 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol dihydrochloride dihydrate, K6PW2S574L, Amodiaquine hydrochloride [USP], CAM-AQ 1, NCGC00017063-01, CAS-6398-98-7, SN 10751, Amodiaquine hydrochloride (USP), CHEBI:50652, 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride, Amodiaquin dihydrochlorid-2-wasser, Prestwick_677, Amodiaquin diHCl dihydrate, AC1L21NB, Camoquin hydrochloride (TN), DSSTox_CID_25568, DSSTox_RID_80965, DSSTox_GSID_45568, CHEMBL1357648, DTXSID3045568, CTK8F7747, KS-00000SRX, S4589 Amodiaquin (dihydrochlori, MolPort-019-999-825, C20H22ClN3O.2HCl.2H2O, HMS1568N20, HY-B1322, Tox21_110765, s4589, AKOS016339633, CCG-220309, CS-4895, KS-1326, KS-5250, TRA0068429, 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol dihydrochloride dihydrate, NCGC00017063-02, NCGC00017063-03, AK164307, FT-0740309, ST24042755, D02466, A834604, Z1563146060, 4-(7-Chloro-4-quinolinylamino)-2-(diethylaminomethyl)phenol dihydrochloride dihydrate, 4-[(7-chloranylquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol dihydrate dihydrochloride, 4-[(7-chloro-4-quinolinyl)amino]-2-(diethylaminomethyl)phenol dihydrate dihydrochloride, 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol dihydrate dihydrochloride, 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol dihydrate dihydrochloride, o-Cresol, 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-, dihydrochloride, dihydrate, Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-, dihydrochloride, dihydrate, AC1LAOEE, [5-[(7-chloroquinolin-1-ium-4-yl)amino]-2-hydroxyphenyl]methyl-diethylazanium dichloride dihydrate, AKOS026749883

ID: 2759

chemical graph of compound 2759



InChIKey: YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES: CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10206
synonyms found at PubChem are:
CEPHARANTHINE, 481-49-2, Cepharanthin, (+)-Cepharanthine, O-Methylcepharanoline, Cepharantin, Cepharanthine [JAN], UNII-7592YJ0J6T, CCRIS 6539, C37H38N2O6, NSC 623442, 6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))oxyacanthan, BRN 0075231, CHEBI:3546, 7592YJ0J6T, NSC623442, Cepharanthine (JAN), ecaene (non-preferred name), DSSTox_CID_25957, DSSTox_RID_81253, DSSTox_GSID_45957, Oxyacanthan, 6',12'-dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))-, CAS-481-49-2, SR-01000779734, NSC-623442, Cepharanthin,(S), NCGC00095194-01, (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dod, Cepharanthine (TN), AC1L1UPH, Spectrum2_000832, Spectrum3_001963, UPCMLD-DP054, BSPBio_003563, 4-27-00-09061 (Beilstein Handbook Reference), MLS000728518, SCHEMBL154545, SPECTRUM1505322, SPBio_000783, CHEMBL449782, DTXSID6045957, UPCMLD-DP054:001, KBio3_002909, Cepharanthine, >=95% (HPLC), Cepharanthine, >=98% (HPLC), MolPort-000-775-465, HMS1922J12, HMS2232F21, Pharmakon1600-01505322, Tox21_111483, BBL030154, BDBM50423643, CCG-40294, NSC758965, s4238, STK801907, ZINC30726863, AKOS004119865, Tox21_111483_1, MCULE-4243165865, NSC-758965, SDCCGMLS-0066893.P001, NCGC00161621-01, NCGC00161621-02, NCGC00161621-03, NCGC00161621-05, AC-15206, AN-45199, AS-17451, LS-52756, SC-14006, SMR000445632, SBI-0207049.P001, FT-0082435, V0178, C09391, D01035, AB00643356_08, AB00643356_09, 481C492, Q-100524, SR-01000779734-3, SR-01000779734-4, BRD-K96194081-001-06-0, 6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))-oxyacanthan, 6',12'-Dimethoxy-2,2'-dimethyl-6,7-[methylenebis-(oxy)]oxyacanthan, Oxyacanthan, 6',12'-dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))- (9CI), (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2(16,19).1(3,10).1(21,25).0(4,8).0(14,39).0(31,35)]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene, (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2??,??.1?,??.1??,??.0?,?.0??,??.0??,??]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene

ID: 2760

chemical graph of compound 2760



InChIKey: YVUQSNJEYSNKRX-UHFFFAOYSA-N
SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 16362
synonyms found at PubChem are:
pimozide, Orap, 2062-78-4, Opiran, Pimozidum, Pimozidum [INN-Latin], McN-JR-6238, pimozida, Primozida, R-6238, Primozida [INN-Spanish], Primozide, R 6238, Pimozida [INN-Spanish], UNII-1HIZ4DL86F, NSC 170984, McN-JR 6238, CCRIS 9172, C28H29F2N3O, Orap (TN), Pimozide [USAN:INN:BAN:JAN], EINECS 218-171-7, 1-(1-(4,4-Bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone, 1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone, BRN 0729089, 1HIZ4DL86F, CHEMBL1423, 1-(4,4-Bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine, 1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, MLS000028410, MLS002702058, CHEBI:8212, 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one, NSC170984, 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one, 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-, NCGC00015802-08, NCGC00015802-18, SMR000058385, CAS-2062-78-4, DSSTox_CID_3474, P 1793, 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, 2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-, DSSTox_RID_77042, DSSTox_GSID_23474, Antalon, Orap forte, 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine, 2-Benzimidazolinone, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-, 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one, SR-01000075392, 2-Benzimidazolinone, 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-, Prestwick_395, Pimozide [USAN:USP:INN:BAN:JAN], Spectrum_000445, Tocris-0937, Opera_ID_1580, Prestwick0_000308, Prestwick1_000308, Prestwick2_000308, Prestwick3_000308, Spectrum2_001026, Spectrum3_001451, Spectrum4_000420, Spectrum5_001308, Lopac-P-1793, Janssen Brand of Pimozide, D00KHM, GTPL90, NCIMech_000356, AC1L27SR, AC1Q4NM9, Pimozide (JAN/USP/INN), Lopac0_000946, SCHEMBL41584, BSPBio_000276, BSPBio_001439, BSPBio_002941, KBioGR_000720, KBioSS_000925, 5-24-02-00367 (Beilstein Handbook Reference), MLS001077311, BIDD:GT0435, DivK1c_000386, SPECTRUM1501134, Pimozide (JP17/USP/INN), SPBio_001211, SPBio_002495, ASTA Medica Brand of Pimozide, AC1Q4M09, BPBio1_000304, Pharmascience Brand of Pimozide, SCHEMBL7519553, DTXSID8023474, BCBcMAP01_000043, CTK8G2428, HMS501D08, KBio1_000386, KBio2_000925, KBio2_003493, KBio2_006061, KBio3_002441, AOB5780, MolPort-001-736-597, NINDS_000386, YVUQSNJEYSNKRX-UHFFFAOYSA-N, HMS1568N18, HMS1791H21, HMS1921H19, HMS1989H21, HMS2089C11, HMS2092F09, HMS2095N18, HMS2231P23, HMS3262N14, HMS3267E19, HMS3370N13, HMS3402H21, HMS3712N18, Pharmakon1600-01501134, KS-000018AL, ZINC4175630, Tox21_110224, Tox21_301586, Tox21_500946, BDBM50334150, BG0381, CCG-35918, CCG-36461, CCG-39728, MFCD00055081, NSC757854, AKOS024458706, Tox21_110224_1, API0003851, DB01100, LP00946, NSC-170984, NSC-757854, IDI1_000386, SMP1_000241, NCGC00015802-01, NCGC00015802-02, NCGC00015802-03, NCGC00015802-04, NCGC00015802-05, NCGC00015802-06, NCGC00015802-07, NCGC00015802-09, NCGC00015802-10, NCGC00015802-11, NCGC00015802-12, NCGC00015802-13, NCGC00015802-14, NCGC00015802-15, NCGC00015802-16, NCGC00015802-26, NCGC00016601-01, NCGC00022282-03, NCGC00024888-01, NCGC00024888-02, NCGC00024888-03, NCGC00024888-04, NCGC00024888-05, NCGC00024888-06, NCGC00024888-07, NCGC00255294-01, NCGC00261631-01, AN-50194, AS-13916, HY-12987, LS-33236, M828, SBI-0050920.P003, AB00052215, CS-0012921, EU-0100946, FT-0673903, C07566, D00560, AB00052215-06, AB00052215_07, AB00052215_08, 062P784, 117210-EP2272537A2, 117210-EP2275420A1, 117210-EP2295061A1, 117210-EP2298776A1, L000494, WLN: T56 BMVNJ D- DT6NTJ A3YR DF&R DF, J-013477, SR-01000075392-1, SR-01000075392-3, SR-01000075392-4, SR-01000075392-6, BRD-K01292756-001-06-0, BRD-K01292756-001-13-6, Pimozide, European Pharmacopoeia (EP) Reference Standard, Z241910386, 2-Benzimidazolinone,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-, N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine, Pimozide, United States Pharmacopeia (USP) Reference Standard, 1-[1-[4,4-Bis(p-flurophenyl)butyl]-4-piperidyl]-2-benzimidazolinone, 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H- benzimidazol-2-one, 1-{1-[4,4-bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one, 2H-Benzimidazol-2-one,1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-, 2H-Benzimidazol-2-one,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-, 1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide), PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE

ID: 2761

chemical graph of compound 2761



InChIKey: YWAFNFGRBBBSPD-OCMLZEEQSA-M
SMILES: C[N+](C)(C)CCOP(=O)([O-])OP(=O)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=NC2=O)N)O)O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 36605
synonyms found at PubChem are:
CITICOLINE SODIUM, Citicoline sodium salt, 33818-15-4, UNII-7XQ5AKD9YD, IP 302 sodium, CDP-choline, Brassel, Cebroton, Flussorex, Gerolin, Neurotron, Sinkron, Logan, CDP-cholin, cidifos, citicoline, MLS000028567, 7XQ5AKD9YD, Citicoline sodium [USAN], CerAxon, MFCD00150508, SMR000058983, Citicoline sodium (USAN), DSSTox_CID_25760, DSSTox_RID_81103, DSSTox_GSID_48981, CDP-coline, CDP-choline-Na, cytidine diphosphate choline, CAS-33818-15-4, Acticolin, cytidine 5'-diphosphocholine sodium, Acticolin-d9, Flussorex-d9, Neurotron-d9, Cebroton-d9, Brassel-d9, Cidifos-d9, Gerolin-d9, Sinkron-d9, Logan-d9, EINECS 251-689-1, CerAxon (TN), Citicoline-d9 Sodium, Cytidine 5-diphosphocholine sodium salt, Opera_ID_98, IP-302-Sodium, Citicoline Sodium,(S), CYTIDINE 5'-DIPHOSPHOCHOLINE SODIUM SALT, IP 302-d9 Sodium, NCGC00183032-01, Citicoline-d9 Sodium Salt, AC1L1W3C, SCHEMBL667104, Jsp006161, CHEMBL1256994, DTXSID4048981, MolPort-023-298-836, YWAFNFGRBBBSPD-OCMLZEEQSA-M, HMS2230N10, Tox21_111218, Tox21_113440, AKOS015896462, C14H25N4NaO11P2??2H2O, Choline hydroxide, 5'-ester with cytidine 5'-(sodium dihydrogen diphosphate), inner salt, AS-12295, MLS-0072913.P020, Cytidine 5'-diphosphocholine monosodium salt, ST24046355, D03528, I06-1933, Cytidine 5'-(Trihydrogen Diphosphate) P'-[2-(Trimethylammonio)ethyl] Ester Inner Salt Sodium Salt, Cytidine 5'-(Trihydrogen Diphosphate) P'-[2-(Trimethylammonio-d9)ethyl] Ester Inner Salt Sodium Salt, Cytidine 5'-(trihydrogen diphosphate), mono(2-(trimethylammonio)ethyl) ester, hydroxide, inner salt, monosodium salt, Cytidine 5'-(trihydrogen diphosphate), P'-(2-(trimethylammonio)ethyl) ester, inner salt, monosodium salt, P'-[2-(Trimethylammonio)-ethyl]-ester cytidine 5'-(tri-hydro-gen di-phos-phate) inner salt monosodium, sodium [[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] 2-(trimethylazaniumyl)ethyl phosphate, sodium;[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] 2-(trimethylazaniumyl)ethyl phosphate

ID: 2762

chemical graph of compound 2762



InChIKey: YWPZOTNKHMBWPD-QAWKRFFXSA-N
SMILES: C[C@H]1[C@H]2CN3CCC4=C([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)NC5=CC=CC=C45.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 168978
synonyms found at PubChem are:
Ajmalicine hydrochloride, Ajmalicine, hydrochloride, UNII-I0V9KZN41X, gamma-Yohimbin hydrochloride, 4373-34-6, gamma-Yohimbine hydrochloride, RAUBASINE HYDROCHLORIDE, EINECS 224-471-9, I0V9KZN41X, Methyl (19alpha)-16,17-didehydro-19-methyloxayohimban-16-carboxylate hydrochloride, Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, monohydrochloride, Ajmalicine, monohydrochloride, Prestwick_8, AC1L52WI, AC1Q3E9M, MLS002153894, C21H24N2O3.HCl, SCHEMBL4135134, CHEMBL1554397, HMS1569H06, Ajmalicine, monohydrochloride (8CI), AKOS015916623, ajmalicine, hydrochloride(19alpha)-isomer, AN-45213, LS-15652, SMR001233243, I14-51617, (4S,4aR,13bS,14aS)-methyl 4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate hydrochloride

ID: 2763

chemical graph of compound 2763



InChIKey: YWTYJOPNNQFBPC-UHFFFAOYSA-N
SMILES: C1CN(C(=N1)N[N+](=O)[O-])CC2=CN=C(C=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 86418
synonyms found at PubChem are:
Imidacloprid, 138261-41-3, Admire, Provado, 105827-78-9, Confidor, Premise 75, Gaucho, Merit, Confidor SL, (E)-imidacloprid, Merit (insecticide), Imidacloprid [ISO], Confidor 200 SL, Advantage Flea Adulticide, (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, (Z)-imidacloprid, C9H10ClN5O2, UNII-3BN7M937V8, 1-((6-Chloro-3-pyridyl)methyl)-N-nitro-2-imidazolidinimine, CP 1, 1-((6-Chloro-3-pyridinyl)methyl)-N-nitro-2-imidazolidinimine, BAY-NTN 33893, HSDB 7373, Imidacloprid (old RN), NTN 33893, NTN 33893-240FS, EPA PEsticide Chemical Code 129099, (2Z)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, CHEBI:5870, CHEMBL406819, YWTYJOPNNQFBPC-UHFFFAOYSA-N, 3BN7M937V8, NCGC00166169-01, 2-Imidazolidinimine, 1-((6-chloro-3-pyridinyl)methyl)-N-nitro-, 2-Imidazolidinimine, 1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-, DSSTox_CID_12442, DSSTox_RID_78948, DSSTox_GSID_32442, 1-(2-Chloro-5-pyridylmethyl)-2-(nitroimino)imidazolidine, Hachikusan, Imidaclopride, Meritgreen, Baimieshi, Confidate, Couraze, Imicide, Kohinor, Advise, Alias, Grubex, CoreTect, ProAgro, Gaucho Grande, Couraze Max, Admire Pro, Preventol TM, Trimax Pro, Macho Max, Marathon II, 1-((6-Chloro-3-pyridinyl)methyl)-4,5-dihydro-N-nitro-imidazol-2-amine, 1H-Imidazol-2-amine, 1-((6-chloro-3-pyridinyl)methyl)-4,5-dihydro-N-nitro-, 1H-Imidazol-2-amine, 1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydro-N-nitro-, 1H-Imidazol-2-amine, 4,5-dihydro-1-((6-chloro-3-pyridinyl)methyl)-N-nitro-, 2-Imidazolidinimine, 1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-, (2E)-, N-[1-[(6-chloropyridin-3-yl)methyl]-4,5-dihydroimidazol-2-yl]nitramide, Admire 2F, Mallet 2F, Confidor 70WG, Alias 2F, Confidor 200SL, CAS-138261-41-3, Gaucho 600FS, Premise (insecticide), Senator (neonicotinoid), Confidor 200 O-TEQ, Confidor 240 O-TEQ, CCRIS 9318, (NE)-N-[1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-ylidene]nitramide, N-[1-[(6-chloro-3-pyridyl)methyl]-4,5-dihydroimidazol-2-yl]nitramide, AGST 03001, Imidacloprid solution, AEF 106464, Bayer Advanced Season-Long Grub control, 1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine, AE-F 106464-00GR01B0, EC 428-040-8, AC1L3BI5, Bayer Brand of Imidacloprid, SCHEMBL22278, MLS001304087, IMI070, DTXSID5032442, SCHEMBL12002532, CHEBI:39168, CHEBI:39169, YWTYJOPNNQFBPC-UHFFFAOYSA-, MolPort-000-770-602, MolPort-002-747-983, MolPort-003-931-374, MolPort-005-933-877, HMS2231F05, HMS3373H06, ALBB-017950, BCP10193, HY-B0838, ZINC4474604, ZX-AN016636, Tox21_111298, Tox21_113358, Tox21_301028, BBL012806, BDBM50212288, LS-809, STK786692, AKOS004119901, AKOS005622077, AKOS015895351, AKOS015994761, AKOS028109228, Tox21_111298_1, CS-6904, DB11421, LD-0259, MCULE-7224198077, NCGC00163736-01, NCGC00163736-02, NCGC00163736-03, NCGC00163736-04, NCGC00254930-01, AN-31828, AN-33871, BC218951, H169, LS-77945, SC-18937, SMR000718777, Imidacloprid 10 microg/mL in Acetonitrile, AB0222177, Imidacloprid 100 microg/mL in Acetonitrile, KB-124672, 292-EP2274983A1, 292-EP2275422A1, 292-EP2280009A1, 292-EP2281812A1, 292-EP2292608A1, 292-EP2298076A1, 292-EP2298077A1, 292-EP2301353A1, 292-EP2305031A1, 292-EP2305034A1, 292-EP2305035A1, 292-EP2305658A1, 292-EP2305662A1, 292-EP2308857A1, 292-EP2308858A1, 292-EP2311816A1, 292-EP2311817A1, 292-EP2314583A1, 292-EP2377845A1, FT-0631157, FT-0656073, R4841, C11110, J90054, 1-(6-Chloronicotinyl)-2-nitroiminoimidazolidine, AB00876233-04, A801327, IMIDACLOPRID (CAS NO. 105827-78-9), I06-0728, J-007111, 1-(2-chloro-5-pyridylmethyl)-2-nitroiminoimidazolidine, 1-(6-chloro-3-pyridyl)methyl-2-nitroiminoimidazolidine, 1-(2-chloro-5-pyridyl-methyl)-2-(nitroimino)imidazolidine, 1-(6-chloro-3-pyridylmethyl)-N-nitromidazolidin-2-ylideneamine, 1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, Imidacloprid 100 mg/L in Acetonitrile (RM, ISO GUIDE 34), 1-(6-Chloropyridin-3-ylmethyl)-N-nitroimidazolidin-2-ylidenamine, 2-chloro-5-{[(2Z)-2-(nitroimino)imidazolidin-1-yl]methyl}pyridine, (E)-N-(1-((6-chloropyridin-3-yl)methyl)imidazolidin-2-ylidene)nitramide, (ez)-1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine, (Z)-N-(1-((6-chloropyridin-3-yl)methyl)imidazolidin-2-ylidene)nitramide, 1-((6-chloro-3-pyridinyl)methyl)-n-nitro-4,5-dihydro-1h-imidazol-2-amine, 2-Chloro-5-(((2Z)-2-[oxido(oxo)hydrazono]imidazolidinyl)methyl)pyridine #, N-[1-[(6-chloranylpyridin-3-yl)methyl]-4,5-dihydroimidazol-2-yl]nitramide, N-[1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydroimidazol-2-yl]nitramide, 1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-N-nitro-1H-imidazol-2-amine, 9CI, 2-{1-[(6-chloro-3-pyridyl)methyl]tetrahydro-2H-imidazol-2-yliden}-1-oxo-1-hydraziniumolate, N-(1-((6-chloropyridin-3-yl)methyl)-4,5-dihydro-1H-imidazol-2-yl)nitramide, 1223531-53-0, 1248963-04-3, 936094-08-5, 937701-26-3, InChI=1/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)

ID: 2764

chemical graph of compound 2764



InChIKey: YXIWHUQXZSMYRE-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)NC(=S)S2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8997
synonyms found at PubChem are:
2-Mercaptobenzothiazole, 149-30-4, 2-Benzothiazolethiol, Captax, Benzothiazolethiol, Benzo[d]thiazole-2-thiol, Benzothiazole-2-thiol, 1,3-Benzothiazole-2-thiol, Rotax, 2(3H)-Benzothiazolethione, Accelerator M, MERCAPTOBENZOTHIAZOLE, Dermacid, Sulfadene, Kaptax, Mertax, Thiotax, Rokon, Benzo[d]thiazole-2(3H)-thione, Vulkacit M, Ekagom G, Accel M, 2-MBT, Mebetizole, Mebithizol, Kaptaks, Nuodeb 84, Soxinol M, Vulkacit Mercapto, Pneumax MBT, 2-Mercaptobenzthiazole, Royal MBT, Mercaptobenzothiazol, Mercaptobenzthiazole, Vulkacit Mercapto/C, 2-Mercptobenzothiazole, Pennac mbt powder, Benzothiazole-2-thione, 2-Benzothiazolinethione, mebetizol, Nuodex 84, Usaf gy-3, Nocceler M, Usaf xr-29, MBT, Benzothiazole, mercapto-, 2-Benzothiazolyl mercaptan, 118090-09-8, 2-Merkaptobenzotiazol, 2-Merkaptobenzthiazol, AG 63, Perkacit MBT, 1,3-Benzothiazol-2-yl hydrosulfide, Kaptax [Czech], 2-thiobenzothiazole, Mercaptobenzothiazole (VAN), Caswell No. 541, benzothiazolyl mercaptan, 2-Mercapto benzothiazole, pennac mbt, CHEBI:34292, Thiot ax, NCI-C56519, UNII-5RLR54Z22K, 2-benzothiazolthiol, Accelerator mercapto, C7H5NS2, CCRIS 891, Bantex, 2-Merkaptobenzthiazol [Czech], 2-sulfanyl-1,3-benzothiazole, 2-Merkaptobenzotiazol [Polish], 3H-1,3-benzothiazole-2-thione, HSDB 4025, 2-Mercaptobenzothioazole, 2-mercapto-benzothiazole, captax, zinc salt, NSC 2041, EINECS 205-736-8, captax, sodium salt, EPA Pesticide Chemical Code 051701, AI3-00985, 5RLR54Z22K, 155-04-4 (zinc salt), 2-Mercaptobenzothiazole (in liquid mixtures), NSC2041, YXIWHUQXZSMYRE-UHFFFAOYSA-N, 7778-70-3 (potassium salt), 4162-43-0 (copper(+2) salt), NCGC00091643-07, NCGC00091643-08, DSSTox_CID_807, DSSTox_RID_75799, DSSTox_GSID_20807, 3-hydrobenzothiazole-2-thione, 2(3H)-Benzothiazolethione, potassium salt, CAS-149-30-4, captax, potassium salt, captax, lead(+2) salt, captax, cobalt(+2) salt, captax, copper(+2) salt, captax, silver(+1) salt, captax, bismuth(+3) salt, captax, mercury (+2) salt, Drmacid, thiotax(tm), rokon(r), MBT, captax, mercapto-benzothiazole, mercaptobenzothiazole;, 2-Benzothiazolethione, 2-mercaptobenzothiazol, 2-mercapto-benzthiazole, PubChem20577, Spectrum_001669, 2-Mercaptobenzothiazolyl, SpecPlus_000728, 2-thiocarbamidothiophenol, AC1LF5KF, AC1Q7FDD, 57948-09-1, Spectrum2_001666, Spectrum3_001665, Spectrum4_000628, Spectrum5_001400, mercapto(2-)benzothiazole, benzo[d]thiazole-2-thione, Epitope ID:116044, EC 205-736-8, Benzothiazole, 2-mercapto-, ACMC-1C6V5, 2-Benzothiazolethiol (9CI), SCHEMBL23237, 1,3-Benzothiazole-2-thione, BSPBio_003449, KBioGR_001216, KBioSS_002149, KSC159S8T, BIDD:ER0373, DivK1c_006824, SPECTRUM1504225, SPBio_001851, 2-Mercaptobenzothiazole, 97%, CHEMBL111654, WLN: T56 BN DSJ CSH, DTXSID1020807, Vulkacit M, vulkacit merkapto/c, CTK0F9989, KBio1_001768, KBio2_002149, KBio2_004717, KBio2_007285, KBio3_002669, 2-Mercaptobenzothiazole (2-MBT), MolPort-001-029-534, MolPort-001-826-176, 1,3-benzothiazol-2-ylhydrosulfide, LS-61, 2(3H)-Benzothiazolethione (9CI), EBD46479, NSC-2041, 2492-26-4 (hydrochloride salt), Tox21_113450, Tox21_400016, 2953AA, ANW-21199, BBL003621, BDBM50444459, c1019, CCG-39092, MFCD00005781, SBB037840, STK499589, ZINC18098783, AKOS000119128, AKOS002337495, 1,3-Benzothiazol-2-yl hydrosulfide #, 2-Mercaptobenzothiazole, 97% 100g, CS-W017829, FS-1801, MCULE-4331370211, RP23031, RTR-006035, TRA0026553, KS-000001D2, NCGC00091643-01, NCGC00091643-02, NCGC00091643-04, NCGC00091643-05, NCGC00091643-06, NCGC00091643-09, 29904-98-1 (cobalt(+2) salt), 32510-27-3 (unspecified copper salt), 81605-65-4, AC-11606, AN-44000, BC202804, KB-68910, L287, SC-18901, ST023801, 26622-66-2 (mercury (+2) salt), AB0003265, AB1002882, DB-042988, KB-168536, KB-250781, KB-271347, ST2412662, TL8001072, TR-006035, FT-0612758, FT-0699702, M0055, M0247, T7418, 49M304, C14437, 2-Mercaptobenzothiazole, technical, >=90% (T), AB00053232-04, A808877, AE-641/31369054, I09-0270, Q-200294, BRD-K55160477-001-02-1, BRD-K55160477-001-03-9, F3066-0005, Z1250100728, 112242-83-8, 119170-41-1, 12640-90-3, 1321-08-0, 27157-85-3, 4464-58-8, 55199-93-4

ID: 2765

chemical graph of compound 2765



InChIKey: YYBNDIVPHIWTPK-KYJQVDHRSA-N
SMILES: C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6150
synonyms found at PubChem are:
Eserine sulphate, Physostigmine SO4, Physostigmine sulfate (2:1), Eserine sulfate, Physostigmine sulphate, PHYSOSTIGMINE SULFATE, EINECS 200-585-4, Physostigmine hemisulfate, Physostigmine sulfate [USP], UNII-G63V2J2N71, Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS,8aR)-, sulfate (2:1) (salt), Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-, sulfate (2:1), Pyrrolo(2,3-b)indole, 1,2,3,3a,8,8a-hexahydro-5-hydroxy-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-, sulfate (2:1), G63V2J2N71, 2C15H21N3O2.H2O4S, physostigmine sulfate(usp), AC1L1LWF, 64-47-1, AC1Q22KK, Physostigmine sulfate [USAN], LS-139388, [(3aS,8bS)-3,4,8b-trimethyl-1,2,3,3a-tetrahydropyrrolo[2,3-b]indol-3-ium-7-yl] N-methylcarbamate sulfate, 11036-67-2, 11041-29-5, Eserine sulfate, physostigmine sulfate, Eserine hemisulfate salt, ESERINE HEMISULFATE, Physostigmine sulfate (USP), Prestwick_206, Eserine sulfate (TN), AC1O4WGE, SCHEMBL63288, Physostigmine hemisulfate salt, CHEMBL2105891, CTK8G2408, bis(physostigmine); sulfuric acid, HMS1569B14, HMS2096B14, HMS3713B14, 2402AH, MFCD06795853, AKOS030254937, CCG-220566, D03826, SR-01000872637, SR-01000872637-1, [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate; sulfuric acid

ID: 2766

chemical graph of compound 2766



InChIKey: YYLQUHNPNCGKJQ-LWMBPPNESA-N
SMILES: [C@H]([C@@H](C(=O)O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 443239
synonyms found at PubChem are:
DL-threo-beta-Hydroxyaspartic acid, 7298-99-9, UNII-Z9Q5W0U8VW, (2S,3S)-2-amino-3-hydroxybutanedioic acid, L-(-)-threo-3-Hydroxyaspartic acid, Z9Q5W0U8VW, DL-threo-beta-hydroxyaspartate, CHEBI:10696, (3S)-3-hydroxy-L-aspartic acid, D,L-threo-beta-Hydroxy Aspartic Acid, 4294-45-5, beta-Hydroxyaspartic acid, L-threo-beta-Hydroxyaspartic acid, L-threo-3-Hydroxyaspartate, threo-3-Hydroxy-L-aspartate, 3-Hydroxyaspartic acid, threo-beta-Hydroxyaspartate, SR-01000075907, Threo-3-hydroxy-DL-aspartic acid, beta-Hydroxyaspartic acid, l-threo-, EINECS 224-299-4, beta-Hydroxy-L-aspartic acid, threo-, L-Aspartic acid, 3-hydroxy-, (3S)-, Tocris-0183, DL-THA, AC1L9EAT, D0JT2N, Lopac0_000564, (3S)-3-Hydroxyaspartic acid, GTPL4497, L-threo-?-Hydroxyaspartic acid, SCHEMBL1130719, CHEMBL1231330, BDBM85209, CTK8F8919, MolPort-003-847-751, YYLQUHNPNCGKJQ-LWMBPPNESA-N, HMS3261B10, ZINC901878, Tox21_500564, D,L-threo-|A-Hydroxy Aspartic Acid, AKOS006275015, CCG-204654, LP00564, NCGC00024486-01, NCGC00024486-02, NCGC00024486-03, NCGC00024486-04, NCGC00024486-05, NCGC00261249-01, SC-10301, (2S,3S)-2-amino-3-hydroxy-succinic acid, B6218, EU-0100564, C11511, DL-tHya, threo-2-Amino-3-hydroxysuccinic Acid, H 2775, SR-01000597674, UNII-F1 component YYLQUHNPNCGKJQ-LWMBPPNESA-N, SR-01000075907-1, SR-01000075907-4, SR-01000597674-1, UNII-VI4F0K069V component YYLQUHNPNCGKJQ-LWMBPPNESA-N, UNII-Z9Q5W0U8VW component YYLQUHNPNCGKJQ-LWMBPPNESA-N

ID: 2767

chemical graph of compound 2767



InChIKey: YYQLEVUVEAKBKB-UHFFFAOYSA-N
SMILES: COC1=C(C(=C(C=C1)C(=O)C2=CC=C(C=C2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3908719
synonyms found at PubChem are:
2,3,4'-TRIHYDROXY-4-METHOXYBENZOPHENONE, KBio3_001171, AC1MZYZW, Spectrum_000567, SpecPlus_000353, Spectrum2_000204, Spectrum3_000176, Spectrum4_001496, Spectrum5_000231, BSPBio_001671, KBioGR_002131, KBioSS_001047, SPECTRUM200412, DivK1c_006449, SPBio_000187, SCHEMBL4007482, CHEMBL1599728, KBio1_001393, KBio2_001047, KBio2_003615, KBio2_006183, CCG-39999, NCGC00095817-01, NCGC00095817-02, BRD-K53923343-001-03-4, (2,3-dihydroxy-4-methoxyphenyl)-(4-hydroxyphenyl)methanone

ID: 2768

chemical graph of compound 2768



InChIKey: YYUAYBYLJSNDCX-UHFFFAOYSA-N
SMILES: CC1=CC(=NO1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 54677972
synonyms found at PubChem are:
isoxicam, 34552-84-6, Maxicam, Isoxicamo, Isoxicamum, UNII-8XU734C4NG, Pacyl (antiinflammatory), Isoxicamum [INN-Latin], Isoxicamo [INN-Spanish], EINECS 252-084-5, W 8495, BRN 0577221, 8XU734C4NG, C14H13N3O5S, CHEBI:76163, NCGC00016829-05, CAS-34552-84-6, 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide, DSSTox_CID_25462, DSSTox_RID_80893, DSSTox_GSID_45462, 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide, 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide, 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, SR-01000003112, floxicam, Isoxicam [USAN:BAN:INN], Isoxicam [USAN:INN:BAN], Prestwick_505, Maxicam (TN), AC1NSEWF, Spectrum_001605, Isoxicam (USAN/INN), AC1NS4GQ, Prestwick0_000044, Prestwick1_000044, Prestwick2_000044, Prestwick3_000044, Spectrum2_000862, Spectrum3_001580, Spectrum4_000183, Spectrum5_001253, D03JPH, AC1L1GP8, SCHEMBL25947, BSPBio_000167, BSPBio_003120, Isoxicam, analytical standard, KBioGR_000725, KBioSS_002085, MLS000069554, CHEMBL53292, DivK1c_000661, SPECTRUM1503242, SPBio_000903, SPBio_002088, BPBio1_000185, SCHEMBL1477990, CHEMBL1898455, DTXSID0045462, CTK6C5653, HMS502B03, KBio1_000661, KBio2_002085, KBio2_004653, KBio2_007221, KBio3_002620, MolPort-002-669-818, NINDS_000661, YYUAYBYLJSNDCX-UHFFFAOYSA-N, HMS1568I09, HMS1922M07, HMS2092P16, HMS2095I09, HMS2232A13, HMS3373J12, HMS3712I09, Pharmakon1600-01503242, HY-B1130, Tox21_110634, 2482AH, CCG-40307, MFCD00079374, NSC758436, STK603272, ZINC13130154, ZINC49538599, AKOS005539580, AKOS026749856, Tox21_110634_1, API0007739, CS-4726, DB08942, KS-1364, MCULE-1659746677, NSC-758436, ACM34552846, IDI1_000661, SMP1_000071, NCGC00016829-01, NCGC00016829-02, NCGC00016829-03, NCGC00016829-04, NCGC00016829-06, NCGC00016829-09, NCGC00023881-03, NCGC00023881-04, LS-40540, SMR000058828, SBI-0051800.P002, FT-0725584, ST51015023, D04639, AB00052335_13, AB00052335_14, J-019644, SR-01000003112-2, SR-01000003112-3, (3E)-3-[hydroxy-[(5-methyl-1,2-oxazol-3-yl)amino]methylidene]-2-methyl-1,1-dioxo-1, (3Z)-3-[hydroxy-[(5-methyl-1,2-oxazol-3-yl)amino]methylidene]-2-methyl-1,1-dioxo-1, 3-[hydroxy-[(5-methyl-1,2-oxazol-3-yl)amino]methylidene]-2-methyl-1,1-dioxo-1, (4-hydroxy-2-methyl-1,1-dioxobenzo[e]1,2-thiazin-3-yl)-N-(5-methylisoxazol-3-y l)carboxamide, 3-{hydroxy[(5-methyl-1,2-oxazol-3-yl)amino]methylidene}-2-methyl-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H- 1,2-benzothiazine-3-carboxamide-1,1-dioxide, N-(5-methyl-3-isoxazolyl)-4-hydroxy-2-methyl-2H-1,2-benzthiazine-3-carboxamide 1,1-dioxide

ID: 2769

chemical graph of compound 2769



InChIKey: YYVFXSYQSOZCOQ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 8639
synonyms found at PubChem are:
8-quinolinol sulfate(2:1), AC1L1REJ, 8-Hydroxy-chinolin-sulfat, AC1Q22KR, quinolin-1-ium-8-ol sulfate, 148-24-3 (Parent), Oxyquinoline sulfate [USAN:NF], bis(8-hydroxyquinolinium) sulfate, 8-Hydroxyquinoline sulfate, 98% 1g, MCULE-3699419571, ST50826710, Hydroxyquinoline sulfate, Chinosol, 8-Quinolinol hemisulfate salt, 8-Quinolinol, sulfate (2:1), 8-Hydroxyquinoline hemisulfate salt, quinolin-8-ol;sulfuric acid, Oxychinolinsulfat, 8-Quinolinone Sulfate, AC1LANQZ, quinolin-8-ol hemisulfate, DSSTox_CID_5436, Oxyquinoline sulfate (NF), DSSTox_RID_77785, DSSTox_GSID_25436, Oxyquinoline sulfate [USAN], SCHEMBL324753, CHEMBL1697698, DTXSID6025436, CHEBI:81774, MolPort-001-770-636, ZX-AT029604, Tox21_303537, LS-777, MFCD00013095, OR8254, AKOS015961714, 8-Quinolinol hemisulfate salt, puriss., bis(8 hydroxyquinoline); sulfuric acid, RP20987, C9H7NO.1/2H2SO4.1/2H2O, NCGC00257493-01, AC-14590, AS-13622, BC207913, CAS-134-31-6, I973, Q0017, ST24031595, C18478, D02414, J-006515, J-519475, 8-Quinolinol hemisulfate salt, SAJ first grade, 99.0%, 8-Quinolinol hemisulfate salt, >=98.0% (dry substance, T), yellow, 8-HYDROXYQUINOLINE SULFATE (SEE ALSO 8-HYDROXYQUINOLINE 148-24-3), Oxyquinoline sulfate, United States Pharmacopeia (USP) Reference Standard

ID: 2770

chemical graph of compound 2770



InChIKey: YZLZPSJXMWGIFH-BCXQGASESA-N
SMILES: C1CC(C1)CN2CC[C@]34[C@@H]5[C@H](CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5360733
synonyms found at PubChem are:
NALBUPHINE HYDROCHLORIDE, Nalbuphine HCL, Nubain, 23277-43-2, Nalbufina clorhidrato [Spanish], En 2234A, Nalbuphine hydrochloride [USAN], UNII-ZU4275277R, EN-2234A, EINECS 245-549-9, ZU4275277R, Nubain (TN), 17-(Cyclobutylmethyl)-4,5alpha-epoxymorphinan-3,6alpha,14-triol hydrochloride, (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride, Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, hydrochloride, (5-alpha,6-alpha)-, N-Cyclobutylmethyl-14-hydroxydihydronormorphine hydrochloride, Nalbuphine hydrochloride (USAN), CHEBI:7455, Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, hydrochloride, (5alpha,6alpha)-, Morphinan-3,6-alpha,14-triol, 17-(cyclobutylmethyl)-4,5-alpha-epoxy-, hydrochloride, (4R,4aS,7S,7aR,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol;hydrochloride, Prestwick_344, 17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride hydrate, D06ZXH, C21H32ClNO6, C21H27NO4.HCl, SCHEMBL41123, MLS002154202, CHEMBL1201132, DTXSID20177844, PHN-131, YZLZPSJXMWGIFH-BCXQGASESA-N, HMS1568G18, 20594-83-6 (Parent), API0003485, CCG-220118, PW-4142, LS-92174, SMR001233488, V1613, D00843, Nalbufina clorhidrato, 17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol hydrochloride

ID: 2771

chemical graph of compound 2771



InChIKey: YZODJQFXMFEJRM-UHFFFAOYSA-N
SMILES: CCCCCCC1=C(C=C(C=C1)O)O.C1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 24144
synonyms found at PubChem are:
ACRISORCIN, Akrinol, Acrisorcinum [INN-Latin], Acrisorcina [INN-Spanish], UNII-2U918O4BEV, Sch 7056, 7527-91-5, EINECS 231-389-7, 2U918O4BEV, Bis(9-aminoacridinium)salz des hexylresorcine, Bis(9-aminoacridinium 4-hexyl-1,3-resorcindiolat, 4-Hexylresorcinol compound with 9-aminoacridine (1:1), 9-Aminoacridine compd. with 4-hexylresorcinol (1:1), 1,3-Benzenediol, 4-hexyl-, compd. with 9-acridinamine (1:1), Acrisorcina, Acrisorcinum, Acrisorcin [USAN:INN], Acrisorcin [USAN:USP:INN], Akrinol (TN), C13H10N2.C12H18O2, Spectrum_000107, SpecPlus_000886, Acrisorcin (USAN/INN), Spectrum2_001107, Spectrum3_001213, Spectrum4_000625, Spectrum5_001392, 9-aminoacridine compd with 4-hexylresorcinol, D04VKS, AC1L2N8L, AC1Q79ZK, BSPBio_002626, KBioGR_001210, KBioSS_000547, DivK1c_006982, SCHEMBL148836, SPECTRUM1504218, SPBio_001214, CHEMBL1201038, KBio1_001926, KBio2_000547, KBio2_003115, KBio2_005683, KBio3_002126, DTXSID10226234, HMS1922H03, HMS2093C18, Pharmakon1600-01504218, SCH-7056, CCG-40100, NSC758691, NSC-758691, NCGC00095115-01, NCGC00095115-02, NCGC00095115-03, acridin-9-amine,4-hexylbenzene-1,3-diol, SBI-0052753.P002, acridin-9-amine; 4-hexylbenzene-1,3-diol, LS-177177, D02759, AB00053836_02, SR-05000001975, SR-05000001975-1, BRD-M49658242-001-02-5, BRD-M49658242-001-03-3

ID: 2772

chemical graph of compound 2772



InChIKey: YZYRTEYMUTWJPL-UHFFFAOYSA-N
SMILES: C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 123738
synonyms found at PubChem are:
NNC 711, NO-711 hydrochloride, 145645-62-1, Nnc-711, NO 711, UNII-500M0G931K, 1-(2-(((Diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, 500M0G931K, 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE, 1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride, C21H23ClN2O3, CHEMBL545050, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-(2-(((diphenylmethylene)amino)oxy)ethyl)-, monohydrochloride, SR-01000076236, AC1L3X7A, MLS002153333, C21H22N2O3.HCl, SCHEMBL679911, CTK8F0672, DTXSID20163126, MolPort-003-958-918, Tox21_500880, BN0388, MFCD00153853, AKOS024456774, CCG-222184, LP00880, NCGC00094203-01, NCGC00261565-01, SMR001230746, NO-711 hydrochloride, >=98% (HPLC), LS-173254, RT-014726, B6854, EU-0100880, N-142, X6835, J-008133, SR-01000076236-1, SR-01000076236-3, 1-(2-(((Diphenylmethylene)imino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridine-carboxylic acid hydrochloride, 1-[2-(benzhydrylideneamino)oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid hydrochloride, 3-Pyridinecarboxylicacid,1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro-,hydrochloride(1:1)

ID: 2773

chemical graph of compound 2773



InChIKey: ZAFYATHCZYHLPB-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5732
synonyms found at PubChem are:
zolpidem, 82626-48-0, Ambien, Zolpidemum, Lorex, Zolpidemum [Latin], Zolpidem [INN:BAN], [3H]zolpidem, UNII-7K383OQI23, N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide, CHEMBL911, N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide, DEA No. 2783, CHEBI:10125, ZAFYATHCZYHLPB-UHFFFAOYSA-N, 7K383OQI23, NCGC00095179-01, N,N,6-Trimethyl-2-p-tolylimidazo[1,2-a]pyridine-3-acetamide, SL-800750, N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide, Imidazo[1,2-a]pyridine-3-acetamide,N,N,6-trimethyl-2-(4-methylphenyl)-, SL 800750, DSSTox_CID_25946, DSSTox_RID_81244, DSSTox_GSID_45946, SL 80-0750, Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-, CAS-82626-48-0, zolpidem Ambien, Imidazo[1,2-a]pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-, Zolpidem (INN), Sanval (TN), SL800750, SL-800750-23-N, SL 80.0750, D0Q1LT, D0T1WN, AC1L1L0K, SCHEMBL80516, BSPBio_002278, BIDD:GT0785, SPECTRUM1505369, GTPL4348, GTPL4362, ZINC3876, DTXSID7045946, BDBM26266, CTK8D4202, AOB5703, 2C19H21N3O, HMS1922F22, BCP10205, KS-000000IY, Tox21_111471, MFCD00153885, STK627113, Zolpidem, >=98% (HPLC), solid, AKOS005560130, Tox21_111471_1, API0004656, CCG-213403, CS-1468, DB00425, N,N,6-trimethyl-2-(4-methylphenyl)imidazo(1,2a)pyridine-3-acetamide hemitartrate, NCGC00095179-02, NCGC00095179-03, NCGC00095179-04, NCGC00095179-05, AJ-08185, AN-36130, AS-35386, BC220519, HY-17441, LS-80196, ZB000550, LS-187761, TC-072264, FT-0659828, A-1776, C07219, D08690, AB00698471-07, AB00698471_09, 294Z936, SR-01000763006, I06-0128, SR-01000763006-3, BRD-K44876623-001-01-1, Zolpidem (low-dose oral spray, middle-of-the-night awakenings), Imidazo(1,2-a)pyridine-3-acetamide, 2-(4-methylphenyl)-N,N,6-trimethyl-, N,N,6-Trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide, N,N-dimethyl-2-[6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl]acetamide, Zolpidem (low-dose oral spray, middle-of-the-night awakenings), NovaDel, 6-methyl-N,N-dimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide, N,N,6-Trimethyl-2-(4-Methyl Phenyl) Imidazo [1,2-alpha] Pyridine-3-Acetamide, N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide #, N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[3,2-a]pyridin-3-yl]acetamide, Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, 6-a?5-aChloro-apyridin-a?-ayl)a?a?-ahydroxy-a?,a?-adihydro-apyrrolo[3,a?-ab]apyrazin-a?-aone, ZPM

ID: 2774

chemical graph of compound 2774



InChIKey: ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 51082
synonyms found at PubChem are:
Mitoxantrone hydrochloride, Mitoxantrone dihydrochloride, 70476-82-3, Mitoxantrone HCl, Novantron, Novantrone, Immunex, Bisantrone, CL-232315, UNII-U6USW86RD0, DHAD, Mitoxantrone (dihydrochloride), CCRIS 2592, HSDB 6543, EINECS 274-619-1, NSC 301739, U6USW86RD0, 1,4-dihydroxy-5,8-bis-[2-(2-hydroxyethylamino)ethylamino]anthraquinone 2hcl, CL 232315, Mitozantrone hydrochloride, CHEBI:50727, MITOXANTHRONE HYDROCHLORIDE, novatrone, 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione dihydrochloride, CL 232,315, NSC-301739, 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride, DSSTox_CID_25173, DSSTox_RID_80722, DSSTox_GSID_45173, 1,4-Dihydroxy-5,8-bis-[2-(2-hydroxyethylamino)ethylamino]anthraquinone dihydrochloride, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride, 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione dihydrochloride, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride, 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride, 65271-80-9 (Parent), NCGC00015693-02, CAS-70476-82-3, Onkotrone, Ralenova, Eslep, SR-01000076001, mitoxanthrone hcl, Mitoxantrone Dihcl, Novantron (TN), 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione dihydrochloride, 1,4-dihydroxy-5,8-bis(2-(2-hydroxyethylamino)ethylamino)anthracene-9,10-dione dihydrochloride, 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione dihydrochloride, Prestwick_571, ACMC-20enxy, Mitoxantrone hydrochloride [USAN:JAN], Mitoxantrone hydrochloride [USAN:USP:JAN], AC1L1AED, Mitroxantrone Hydrochloride, SCHEMBL3928, NSC-310739;Novantrone, SPECTRUM1503278, C22H28N4O6.2HCl, C22H30Cl2N4O6, AC1Q3B38, CHEMBL1417019, DTXSID0045173, CTK8F1285, KS-00000XLU, MolPort-003-665-506, ZAHQPTJLOCWVPG-UHFFFAOYSA-N, HMS1569M11, HMS1922O21, BCP23424, dhaq dihydrochloride 65271-80-9, Tox21_110197, Tox21_500779, CCG-39938, HY-13502A, MFCD00242943, s2485, Mitoxantrone hydrochloride (JAN/USP), AKOS015895228, Tox21_110197_1, AC-1591, BCP9000932, CS-2525, LP00779, NSC-310739, NCGC00015693-09, NCGC00094116-01, NCGC00094116-02, NCGC00094116-03, NCGC00094116-04, NCGC00261464-01, AS-13162, BC215535, H492, LS-20325, BCP0726000265, AB0013075, AB2000351, TL8004973, TX-017757, EU-0100779, ST24048109, Mitoxantrone dihydrochloride, >=97% (HPLC), D02166, M 6545, X-2300, 271M809, I06-0260, SR-01000076001-1, SR-01000076001-8, W-104553, Z2569867923, Mitoxantrone dihydrochloride pound>>Mitozantrone dihydrochloride, 70476-82-3,65271-80-9(freebase),70711-41-0(diacetate), Mitoxantrone hydrochloride, European Pharmacopoeia (EP) Reference Standard, 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino-ethyl)amino)anthraquinone dihyrochloride, 1,4-dihydroxy-5,8-bis-[[2-(2-hydroxyethylamino)ethyl]amino]-anthraquinone dihydrochloride, 1,4-dihydroxy-5,8-bis-[2-(2-hydroxyethylamino)ethylamino]anthraquinonedihydrochloride, 1,4-dihydroxy-5,8-bis[[2-(2-hydroxyethylamino)ethyl]amino]anthraquinone dihydrochloride, Mitoxantrone hydrochloride, United States Pharmacopeia (USP) Reference Standard, 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride, AKOS015896216, AKOS015896367, FT-0628954, A835043, I06-1581, I06-1952, 1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione; hydron; dichloride, 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione; hydron; dichloride

ID: 2775

chemical graph of compound 2775



InChIKey: ZAKOWWREFLAJOT-UHFFFAOYSA-N
SMILES: CC1=C2C(=C(C(=C1C)OC(=O)C)C)CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2117
synonyms found at PubChem are:
Tocopheryl acetate, alpha-tochopheryl acetate, DL-alpha-Tocopherol acetate, E-vicotrat, 7695-91-2, Syntopherol acetate, Fertilvit, d-Vitamin E acetate, Rovimix E 50SD, all-rac-alpha-Tocopheryl acetate, Vitamin E acetate dl-form, d,l-alpha-Tocopheryl acetate, Tocopherex, Spondyvit, D-.alpha.-Tocopheryl acetate, DL-alpha-Tocopheryl acetate, E-Ferol, (+-)-alpha-Tocopherol acetate, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl acetate, Ephynal, Vectan (TN), [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] acetate, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate, SMR000857224, O-Acetyl-alpha-tocopherol, .alpha.-Tocopheryl acetate, SR-05000001545, 52225-20-4, D-.alpha.-Tocopherol acetate, Alpha-tocopherol acetate, dl-, CCRIS 6054, (+)-.alpha.-Tocopherol acetate, (+)-.alpha.-Tocopheryl acetate, Eusovit, Vectan, EINECS 257-757-7, (R,R,R)-.alpha.-Tocopheryl acetate, [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] acetate, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate, OptoVit E, SynAC, a-tocopherol acetate, Rovimix E 50, (2R,4'R,8'R)-.alpha.-Tocopheryl acetate, dl-Vitamin E acetate, Vitamin E 500, Spectrum_000257, AC1L1CYI, alpha -tocopherol acetate, alpha -tocopheryl acetate, Spectrum2_000743, Spectrum3_001339, Spectrum4_001814, Spectrum5_000547, vitamin E acetate, (2R-(2R*(4R*,8R*)))-isomer, d-Alpha Tocopheryl Acetate, vitamin E acetate, ((2R*(4R*,8R*))-(+-))-isomer, AC1Q61YQ, D-alpha -tocopherol acetate, D-alpha -tocopheryl acetate, Tocopherol acetate (JP15), BSPBio_003097, KBioGR_002452, KBioSS_000737, SPECTRUM310040, MLS001333081, MLS001333082, DivK1c_000803, dl-.alpha.-Tocopherol acetate, SPBio_000726, (+)-alpha -tocopherol acetate, (+)-alpha -tocopheryl acetate, CHEMBL247481, SCHEMBL1007153, Vitamin E Acid Succiniate-Gran, HMS502I05, KBio1_000803, KBio2_000737, KBio2_003305, KBio2_005873, KBio3_002317, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #, MolPort-003-666-781, NINDS_000803, ZAKOWWREFLAJOT-UHFFFAOYSA-N, DL-Alpha Tocopheryl Acetate 50%, HMS1923I05, HMS2091C13, HMS2233A03, HMS3373K10, Pharmakon1600-00310040, (2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, [2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate, 133-80-2, 1406-70-8, 1407-18-7, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,(2R*(4R*,8R*))-(+-)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, 6-acetate, (2R)-, KS-000000XR, Vitamin E Acid Succiniate - Powder, CCG-40138, HSCI1_000393, NSC755840, SBB012605, AKOS015896288, MCULE-8838142737, NSC-755840, SDCCGMLS-0066580.P001, DL-alpha-TOCOPHEROL ACETATE POWDER, IDI1_000803, NCGC00095255-01, NCGC00095255-02, NCGC00095255-03, NCGC00095255-05, NCGC00095255-06, (2R,4'R,8'R)-alpha-Tocopherol acetate, AN-21824, AN-23611, ST072191, SBI-0051262.P003, AB00051899_06, 006T847, I06-2173, SR-05000001545-1, SR-05000001545-4, I14-51224, 3FA20801-746B-4265-AD7D-988D692C04CF, Acetic acid 2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-tridecyl)-chroman-6-yl ester, Acetic acid 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl ester, 18920-61-1, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate, 6-ACETOXY-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECAN-1-YL)-2H-1-BENZOPYRANE

ID: 2776

chemical graph of compound 2776



InChIKey: ZASHKPXYYPYQRI-UHFFFAOYSA-N
SMILES: CS(=O)(=O)O.C1CCC(CC1)(C2=CC(=CC=C2)N=C=S)N3CCCCC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6604126
synonyms found at PubChem are:
METAPHIT METHANESULFONATE, Metaphit methanesulfonate salt, 99287-12-4, 1-[1-(3-Isothiocyanato)phenyl]cyclohexylpiperidine methanesulfonate salt, SR-01000076019, metaphit mesylate, NCGC00016163-01, Lopac-M-120, AC1O7G9B, metaphit; methanesulfonic acid, MLS002153341, CHEMBL1256971, CTK3I6301, MolPort-003-958-635, HMS2230C06, BN0329, MFCD00069307, SMR001230752, EU-0100843, FT-0671116, M-120, SR-01000076019-1, Metaphit methanesulfonate salt, >=98% (HPLC), solid, 1-(1-[3-Isothiocyanato]phenyl)cyclohexylpiperidine methansulfonate, 1-(1-[3-Isothiocyanato]phenyl)cyclohexylpiperidine, Methanesulfonate Salt, 1-[1-(3-isothiocyanatophenyl)cyclohexyl]piperidine; methanesulfonic acid, Piperidine, 1-[1-(3-isothiocyanatophenyl)cyclohexyl]-, methanesulfonate (1:1)

ID: 2777

chemical graph of compound 2777



InChIKey: ZBIAKUMOEKILTF-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3926
synonyms found at PubChem are:
LIDOFLAZINE, Ordiflazine, Corflazine, Clinium, Lidoflazin, Lidoflazinum, 3416-26-0, Klinium, Angex, Lidoflazina [Italian], McN-JR 7904, UNII-J4ZHN3HBTE, Lidoflazinum [INN-Latin], Lidoflazina [INN-Spanish], Lidoflazine [USAN:INN:BAN], C30H35F2N3O, J4ZHN3HBTE, EINECS 222-312-8, R 7904, BRN 0904339, CHEMBL92870, MCN-JR-7904, 4-(4,4-Bis(p-fluorophenyl)butyl)-1-piperazineaceto-2',6'-xylidide, 1-Piperazineacetamide, 4-(4,4-bis(4-fluorophenyl)butyl)-N-(2,6-dimethylphenyl)-, NCGC00016627-01, NCGC00016627-04, CAS-3416-26-0, 1-Piperazineaceto-2',6'-xylidide, 4-(4,4-bis(p-fluorophenyl)butyl)-, 4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide, 1-(4,4-Bis(4-fluorofenil)butil)-4-((2,6-dimetilanilinocarbonil)metil)piperazina [Italian], DSSTox_CID_25377, DSSTox_RID_80838, DSSTox_GSID_45377, Lidoflazina, 1-Piperazineacetamide, 4-[4,4-bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-, 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,6-dimethylphenyl)acetamide, 2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide, Prestwick_700, Angex (TN), Lidoflazine,98.5%, Prestwick0_000381, Prestwick1_000381, Prestwick2_000381, Prestwick3_000381, Lidoflazine (USAN/INN), D0L7VL, AC1L1H0T, SCHEMBL79037, BSPBio_000561, 5-23-02-00297 (Beilstein Handbook Reference), MLS002153793, SPBio_002482, McN-JR-7094, BPBio1_000619, DTXSID6045377, BDBM23619, CHEBI:93095, CTK8G0582, ZBIAKUMOEKILTF-UHFFFAOYSA-N, HMS1569M03, HMS2096M03, HMS2232O16, HMS3372I14, HMS3713M03, Tox21_110533, MFCD00057353, ZINC22034381, Tox21_110533_1, API0007738, CCG-220381, Lidoflazine, >=98% (HPLC), powder, 1-(4,4-Bis(4-fluorofenil)butil)-4-((2,6-dimetilanilinocarbonil)metil)piperazina, NCGC00016627-02, SMR001233173, LS-110144, X3337, D04733, R-7904, 118379-EP2275420A1, 118379-EP2280008A2, 118379-EP2298764A1, 118379-EP2298765A1, SR-01000841235, J-019473, SR-01000841235-2, BRD-K62996583-001-03-8, 1-[4,4-Bis(fluorophenyl)butyl]-4-(2,6-dimethylanilino carbonylmethyl) piperazine, 2-(4-[4,4-Bis(4-fluorophenyl)butyl]-1-piperazinyl)-N-(2,6-dimethylphenyl)acetamide #, 2-[4-[4,4-bis(4-fluorophenyl)butyl]-1-piperazinyl]-N-(2,6-dimethylphenyl)acetamide

ID: 2778

chemical graph of compound 2778



InChIKey: ZBJJDYGJCNTNTH-UHFFFAOYSA-N
SMILES: CNCCC1=CC=CC=N1.CS(=O)(=O)O.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 198334
synonyms found at PubChem are:
54856-23-4, Betahistine mesilate, Extovyl, Meginalisk, Melopat, Merislon, Riptonin, Tenyl, UNII-X1L0E3R43Y, 2-Pyridineethanamine, N-methyl-, dimethanesulfonate, EINECS 259-377-7, Bethahistinemethanesulfonate, X1L0E3R43Y, 2-(Ethylammonio)-N-methylpyridinium dimethanesulphonate, W-105601, Tenoxican, C8H12N2.2CH4O3S, Suzutolon (TN), Betahistinedimesilate, betahistine dimesylate, Betahistine mesilate [JAN], Betahistine mesilate (JP17), BETAHISTINE DI MESYLATE, SCHEMBL194604, AC1L555B, CHEBI:31274, C10H20N2O6S2, MolPort-027-720-507, HMS2096N07, HMS3713N07, AKOS015898737, API0001688, CCG-220543, LS41082, VA11836, AC-23916, AN-40483, H520, KB-258966, LS-131556, FT-0622912, D01592, n-methyl-2-pyridineethylamine dimethanesulfonate, C-19935, I09-1518, N-Methyl-2-(2-pyridinyl)ethanamine methanesulfonate, SR-01000722006-3, methanesulfonic acid;N-methyl-2-pyridin-2-ylethanamine, methanesulfonic acid; N-methyl-2-(2-pyridyl)ethanamine, N-methyl-2-(pyridin-2-yl)ethanamine dimethanesulfonate

ID: 2779

chemical graph of compound 2779



InChIKey: ZBPAHEUAJMCLRD-BTJKTKAUSA-N
SMILES: CN1CCN(CC1)C2=NC3=C(C=CC(=C3)C(F)(F)F)N4C2=CC=C4.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6438352
synonyms found at PubChem are:
CGS-12066A maleate, CGS 12066B, CPD000468733, CGS-12066A maleate salt, CGS 12066B dimaleate, SR-01000075259, AC1O5PJ2, MLS000860007, MLS001424273, SCHEMBL7746196, CHEMBL1256689, CGS-12066 maleate salt, solid, HMS2052P09, HMS2231A12, HMS3261C05, Tox21_500332, CCG-101182, LP00332, NC00432, NCGC00093772-01, NCGC00261017-01, SAM001247066, SMR000326866, SMR000468733, C-106, EU-0100332, J-006642, SR-01000075259-1, 7-Trifluoromethyl-4(4-methyl-1-piperazinyl)-pyrrolo[1,2-a]quinoxaline maleate, (Z)-but-2-enedioic acid; 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline

ID: 2780

chemical graph of compound 2780



InChIKey: ZBUVYROEHQQAKL-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 92965
synonyms found at PubChem are:
Tolperisone hydrochloride, 3644-61-9, Midocalm, Muscalm, Tolperisone HCl, Tolperisone (hydrochloride), 2,4'-Dimethyl-3-piperidinopropiophenone hydrochloride, EINECS 222-876-5, AV 650, N-553, 2-Methyl-3-piperidino-1-p-tolylpropan-1-one hydrochloride, NCGC00094929-01, 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone hydrochloride, 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, hydrochloride, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-Propanone hydrochloride, DSSTox_CID_25868, DSSTox_RID_81187, DSSTox_GSID_45868, W-106614, Propiophenone, 2,4'-dimethyl-3-piperidino-, hydrochloride, 2-methyl-3-(piperidin-1-yl)-1-p-tolylpropan-1-one hydrochloride, 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one hydrochloride, 2-methyl-1-(4-methylphenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride, CAS-3644-61-9, Arantoick, Atmosgen, Besnoline, Isocalm, Kineorl, Metosomin, 2-methyl-1-(4-methylphenyl)-3-piperidylpropan-1-one, chloride, Abbsa, Tolperisone hydrochloride [JAN], Muscalm (TN), 2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydrochloride, NCGC00182078-02, AC1L3P7D, MLS004773941, SCHEMBL872770, SPECTRUM1501194, Jsp006490, CHEMBL1395150, DTXSID2045868, CHEBI:32244, MolPort-003-666-384, Tolperisone hydrochloride (JP17), ZBUVYROEHQQAKL-UHFFFAOYSA-N, HMS1921P09, Pharmakon1600-01501194, HY-B1139, Tox21_111360, Tox21_113139, BG0665, CCG-40311, MFCD00058211, NSC757872, s4200, SBB058192, AKOS005167032, Tox21_111360_1, AC-4685, API0004446, CS-4744, MCULE-6977793578, NSC-757872, NCGC00094929-02, NCGC00178060-03, 3644-61-9 (HCl), AN-11704, AS-12472, BP-10588, KB-81181, SC-16164, SMR003500666, AB0011989, LS-125221, FT-0603642, ST51015142, A18694, D01507, K-8138, 644T619, C-17744, SR-01000872774, Tolperisone hydrochloride, >=98% (HPLC), solid, SR-01000872774-1, 2,4'-Dimethyl-3-piperidino-propiophenone Hydrochloride, F9995-4198, 2-methyl-3-(1-piperidyl)-1-(p-tolyl)propan-1-one hydrochloride, 2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride, SCHEMBL15663055, AKOS015918417, I14-7905

ID: 2781

chemical graph of compound 2781



InChIKey: ZCDDBUOENGJMLV-QRPNPIFTSA-N
SMILES: CC(C)[C@@H](C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 60772
synonyms found at PubChem are:
Valacyclovir hydrochloride, 124832-27-5, Valaciclovir hydrochloride, Valacyclovir HCl, Valaciclovir Hcl, 256U87 hydrochloride, Valacyclovir (hydrochloride), UNII-G447S0T1VC, BW-256U87, C13H20N6O4.HCl, CHEBI:9919, G447S0T1VC, Valacyclovir hydrochloride [USAN], BW 256, L-Valine, ester with 9-((2-hydroxyethoxy)methyl)guanine, monohydrochloride, DSSTox_CID_24210, DSSTox_RID_80121, DSSTox_GSID_44210, Valacyclovir hydrochloride (USAN), L-Valacyclovir Hydrochloride, 2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl L-valinate hydrochloride, 256U87 HCl, L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, monohydrochloride, (S)-2-((2-AMINO-6-OXO-1H-PURIN-9(6H)-YL)METHOXY)ETHYL 2-AMINO-3-METHYLBUTANOATE HYDROCHLORIDE, 136489-37-7, 256u, CAS-124832-27-5, BW 256U87, NCGC00159520-02, L-valylacyclovir, L-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride, Valacyclovir hydrochloride [USAN:USP], 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methyl-butanoate, acyclovir, L-valyl ester, D05MFA, AC1L1TW2, AC1Q3EH7, SureCN1888797, SureCN5665934, SCHEMBL40830, MLS001401440, SPECTRUM1505368, Valaciclovir Hydrochloride,(S), CHEMBL1201110, DTXSID2044210, MolPort-003-666-655, MolPort-046-033-466, ZCDDBUOENGJMLV-QRPNPIFTSA-N, HMS1922F20, Pharmakon1600-01505368, Valaciclovir hydrochloride (JP17), BCP06722, Tox21_111738, HY-17425A, NSC759101, s1876, AKOS008901386, AKOS015951215, Tox21_111738_1, AC-8065, AN-8355, API0004558, CCG-100889, CCG-213402, CS-1966, H32V264, KS-1126, NC00139, NSC-759101, NCGC00178638-02, BC202740, CPD000469208, KB-62215, SAM001246749, SMR000469208, AB0012705, AB1009371, LS-172602, FT-0631117, V0111, C07184, D00398, L-Valine 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-ylmethoxy)ethyl Ester Hydrochloride, Valaciclovir for system suitability, European Pharmacopoeia (EP) Reference Standard, Valaciclovir hydrochloride (anhydrous), European Pharmacopoeia (EP) Reference Standard, Valacyclovir HCl, Pharmaceutical Secondary Standard; Certified Reference Material, Valacyclovir hydrochloride, United States Pharmacopeia (USP) Reference Standard, 2-((2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester monohydrochloride; L-Valine; Valtrex, 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methyl-butanoate hydrochloride, 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate hydrochloride, L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, hydrochloride (1:1)

ID: 2782

chemical graph of compound 2782



InChIKey: ZCDNRPPFBQDQHR-SSYATKPKSA-N
SMILES: CCOC(=O)OC1=C(C=C(C=C1OC)C(=O)O[C@@H]2C[C@@H]3CN4CCC5=C([C@H]4C[C@@H]3[C@@H]([C@H]2OC)C(=O)OC)NC6=C5C=CC(=C6)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6769
synonyms found at PubChem are:
syrosingopine, Syringopine, 84-36-6, Syrosingopin, Singoserp, Ipores, Elufinesin, Etropres, Isotense, Londomin, Menatensina, Neoreserpan, Novoserpina, Seringina, Serpagon, Siringal, Siringina, Siringone, Siriserpin, Siroshuten, Vegaserpina, Nichiserpine-S, Revelox-wirkstoff, Zentos, Methyl carbethoxysyringoyl reserpate, HF-41T, Carbethoxysyringoyl methylreserpate, UNII-PPG46JF0EG, Syrosingopinum [INN-Latin], Sirosingopina [INN-Spanish], SU 3118, EINECS 201-527-0, NSC 77030, PPG46JF0EG, Methyl reserpate ester of syringic acid ethyl carbonate, Syringic acid ethyl carbonate ester with methyl reserpate, NSC77030, Methyl 18-O-(4-ethoxycarbonyloxy-3,5-dimethoxybenzyoyl)reserpat, Methyl reserpate, 4-ethoxycarbonyl-3,5-dimethoxybenzoic acid ester, 18-O-(3,5-Dimethoxy-4-ethoxycarbonyloxybenzoyl)eserpsaeuremethylester, Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ethyl carbonate, ester with methyl reserpate, Reserpic acid, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate, Methyl 18beta-(4-(ethoxycarbonyloxy)-3,5-dimethoxybenzoyloxy)-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylat, Yohimban-16-carboxylic acid, 18-((4-((ethoxycabonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, Sirosingopina, Syrosingopinum, Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 4-hydroxy, hf 41t, Syrosingopine [INN:BAN:JAN], CAS-84-36-6, Siringina (TN), Syrosingopine [INN:BAN:JAN:NF], NCGC00016336-01, Prestwick_457, C35H42N2O11, Prestwick3_000564, DSSTox_CID_3629, Syrosingopine (JAN/INN), AC1L1N9J, DSSTox_RID_77119, DSSTox_GSID_23629, BSPBio_000348, MLS002153876, SCHEMBL219705, AC1Q65O9, BPBio1_000384, CHEMBL1399124, DTXSID9023629, CHEBI:32175, AOB5345, MolPort-006-110-320, HMS2096B10, HMS2234L13, ZINC4214363, Tox21_110379, NSC-77030, CCG-208497, VA11808, AS-16863, CC-34625, SMR001233230, LS-162727, Methyl reserpate,5-dimethoxybenzoic acid ester, D01659, C-23425, SR-01000838851, SR-01000838851-3, BRD-K14200658-001-02-6, Benzoic acid,5-dimethoxy-, ethyl carbonate, ester with methyl reserpate, WLN: T F6 D5 C666 EM ON&&TTTJ HO1 SOVR CO1 EO1 DOVO2& TO1 UVO1, Reserpic acid, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate, 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-,methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate, 3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester), 3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy-, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate, 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester), 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI), methyl (1R,15S,17R,18R,19S,20S)-17-(4-ethoxycarbonyloxy-3,5-dimethoxybenzoyl)oxy-6,18-dimethoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate, methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({[4-{[(ethyloxy)carbonyl]oxy}-3,5-bis(methyloxy)phenyl]carbonyl}oxy)-11,17-bis(methyloxy)yohimban-16-carboxylate, Yohimban-16-carboxylic acid,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-, Yohimban-16-carboxylicacid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-,methyl ester, (3b,16b,17a,18b,20a)-

ID: 2783

chemical graph of compound 2783



InChIKey: ZCEPWIDYPWMCOY-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(N1CC3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4059895
synonyms found at PubChem are:
1-(4-Chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, 1h-indole-3-acetic acid,1-[(4-chlorophenyl)methyl]-5-methoxy-2-methyl-, 4584-39-8, 2-[1-[(4-chlorophenyl)methyl]-5-methoxy-2-methylindol-3-yl]acetic acid, 2-{1-[(4-chlorophenyl)methyl]-5-methoxy-2-methylindol-3-yl}acetic acid, NCGC00015217-01, Lopac-C-1610, Lopac0_000239, AC1N36K9, SCHEMBL1322507, CHEMBL1256814, ZCEPWIDYPWMCOY-UHFFFAOYSA-N, HMS3260P19, ZINC156826, Tox21_500239, SBB058158, AKOS024374946, CCG-204334, LP00239, MCULE-7136865175, WAY-121316, NCGC00015217-02, NCGC00015217-03, NCGC00015217-04, NCGC00015217-05, NCGC00093702-01, NCGC00093702-02, NCGC00260924-01, KB-214510, KB-303675, EU-0100239, ST51015027, C 1610, SR-01000075743, SR-01000075743-1, 1-(4-Chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, >98% (HPLC), 1-[(4-Chlorophenyl)methyl]-5-methoxy-2-methyl-1H-indole-3-acetic acid

ID: 2784

chemical graph of compound 2784



InChIKey: ZCNBZFRECRPCKU-UHFFFAOYSA-N
SMILES: C1CN(CCC1=C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CCN4C(=O)C5=CC=CC=C5NC4=S

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3013
synonyms found at PubChem are:
diacylglycerol kinase inhibitor ii, 120166-69-0, R59949, R 59949, R 59 949, R-59949, MLS000069510, SMR000058550, 3-[2-[4-(bis(4-Fluorophenyl)methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one, 3-{2-[4-[bis-(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone, 3-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-2-sulfanylidene-1H-quinazolin-4-one, AC1LCWEP, D04SFM, 3-(2-(4-(Bis(4-fluorophenyl)methylene)-1-piperdinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, SCHEMBL317664, CHEMBL261131, cid_657356, GTPL5957, STO500, BDBM43868, CTK8E9214, DTXSID70152707, CHEBI:109551, HMS2232E20, HMS3229C17, HMS3369C17, HSCI1_000348, MFCD00069258, ZINC25782729, CCG-206745, NCGC00018133-01, NCGC00018133-02, NCGC00018133-03, Diacylglycerol Kinase Inhibitor II, solid, FT-0759122, C-54146, J-004272, BRD-K31273080-001-01-2, 3-[2-[4-[bis(4-fluorophenyl)methylene]piperidino]ethyl]-2-thioxo-1H-quinazolin-4-one, 3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one, 3-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one, 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl] -2,3-dihydro-2-thioxo-4(1h)quinazolinone, 3-[2-[4-[bis(4-fluorophenyl)methylidene]-1-piperidinyl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one, 3-[2-[4-[bis(4-fluorophenylmethylene]-1-piperidinyl]ethyl]- 2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 3-[2-[4-[bis(4-fluorophenylmethylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 4(1H)-Quinazolinone, 3-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-, 4(1H)-Quinazolinone,3-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-

ID: 2785

chemical graph of compound 2785



InChIKey: ZCOLJUOHXJRHDI-CMWLGVBASA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5281377
synonyms found at PubChem are:
Genistin, 529-59-9, Genistine, Genisteol 7-monoglucoside, Genistoside, Genistein 7-glucoside, Glucosyl-7-genistein, Genistein 7-O-beta-D-glucoside, UNII-1POG3SCN5T, Genistein glucoside, Genistein-7-glucoside, CHEBI:27514, Genistein, 7-O-beta-D-glucoside, NSC 5112, Genistein, 7-beta-D-glucopyranoside, 1POG3SCN5T, Isoflavone, 4',5,7-trihydroxy-, 7-D-glucoside, Glucopyranoside, genistein-7, beta-D-, BRN 0064479, ZCOLJUOHXJRHDI-CMWLGVBASA-N, C21H20O10, genistein 7-O-glucoside, 4',5,7-trihydroxyisoflavone 7-D-glucoside, 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside, Genistin (8CI), Genistein-7-O-beta-D-glucopyranoside, 7-O-.beta.-D-glucopyranosyl genistein, Genistin,(S), 4',5,7-Trihydroxyisoflavone 7-glucoside, 5-hydroxy-3-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, Prevention 10 (soy isoflavone concentrate), AC1NQYEA, 4',5,7-Trihydroxyisoflavone 7-.beta.-D-glucopyranoside, SCHEMBL62148, Genistin, analytical standard, 4-18-00-02732 (Beilstein Handbook Reference), MLS006010735, BIDD:ER0520, CHEMBL486625, MEGxp0_000436, DTXSID3022324, ACon1_001495, KS-00000XPJ, AOB5041, MolPort-001-740-608, ZX-AFC003190, Genistin, >=97.5% (TLC), HY-N0595, ZINC4097913, Genistein-7-O-|A-D-glucopyranoside, BDBM50025609, MFCD00016883, AKOS025146960, CCG-208377, CS-4240, MCULE-3462482152, NCGC00163559-01, NCGC00163559-02, NCGC00180447-01, AK164233, AN-45603, AS-11684, LS-39678, SC-47264, SMR003929926, FT-0626644, N1860, C09126, S-7711, S-7758, 529G599, Genistin, primary pharmaceutical reference standard, Q-100603, BRD-K51391729-001-01-4, Genistin, from Glycine max (soybean), >=95% (HPLC), UNII-71B37NR06D component ZCOLJUOHXJRHDI-CMWLGVBASA-N, Genistin, United States Pharmacopeia (USP) Reference Standard, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone 7-glucoside, 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-, 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)- (9CI), 4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-, 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one

ID: 2786

chemical graph of compound 2786



InChIKey: ZCTXEAQXZGPWFG-UHFFFAOYSA-N
SMILES: C(NC(=O)NC1C(=O)NC(=O)N1CO)NC(=O)NC2C(=O)NC(=O)N2CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 38258
synonyms found at PubChem are:
Imidazolidinyl urea, 39236-46-9, IMIDUREA, 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea), Germall 115, Imidazolinidyl urea, Imidurea [NF], EINECS 254-372-6, Methanebis(N,N'-(5-ureido-2,4-diketotetrahydroimidazole)-N,N-dimethylol), MLS002154142, CHEBI:51805, Imidurea (NF), N,N''-Methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea), NCGC00164388-01, SMR001233448, 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea), N',N'''-methanediylbis{1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea}, Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-, DSSTox_CID_20151, DSSTox_RID_79449, DSSTox_GSID_40151, 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoylamino]methyl]urea, Methanebis(N,N'-(5-Ureido-2,4-Diketotetrahydroimidazole)-N,N-Dimethylol, N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea), N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea), N,N'-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea), Urea, N,N''-methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-, Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)-, 1,1'-methylenebis{3-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea}, C11H16N8O8, CAS-39236-46-9, AC1L1ZEE, AC1Q6LJH, Prestwick0_001071, Prestwick1_001071, Prestwick2_001071, Prestwick3_001071, EC 254-372-6, SCHEMBL34461, BSPBio_001082, cid_38258, CHEMBL65433, SPBio_002991, BPBio1_001192, DTXSID2040151, BDBM66981, CTK8C4780, MolPort-003-941-818, HMS1571G04, HMS2098G04, HMS2230O16, HMS3369E04, HMS3715G04, HY-B1158, Tox21_112112, Tox21_302325, ANW-73112, SBB058157, AKOS015895558, CCG-221071, COS0000034, CS-4609, MCULE-6258433159, TRA0046318, KS-000018Z5, NCGC00179313-01, NCGC00179313-03, NCGC00255574-01, 71042-94-9 (mono-hydrochloride salt), AK106225, AS-15260, O658, SC-18639, AX8134466, KB-216135, LS-160463, TC-161857, AB00514030, FT-0658132, I0665, ST24036558, ST50307320, D04513, SR-01000841816, I06-1034, SR-01000841816-2, Imidurea, United States Pharmacopeia (USP) Reference Standard, Imidurea, Pharmaceutical Secondary Standard; Certified Reference Material, N,N"-Methylenebis[N"-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea], N,N'-Methylenebis[N'-(3-hydroxymethyl-2,5-dioxo-4-imidazolidinyl)urea], N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea, 1-(2,5-diketo-3-methylol-imidazolidin-4-yl)-3-[[(2,5-diketo-3-methylol-imidazolidin-4-yl)carbamoylamino]methyl]urea, 1-[1-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]- 3-[[[1-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl] carbamoylamino]methyl]urea, 1-[3-(hydroxymethyl)-2,5-bis(oxidanylidene)imidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-bis(oxidanylidene)imidazolidin-4-yl]carbamoylamino]methyl]urea, 1-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-3-[[[[[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]amino]-oxomethyl]amino]methyl]urea, 1-[3-(hydroxymethyl)-2,5-dioxo-imidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxo-imidazolidin-4-yl]carbamoylamino]methyl]urea, 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]c, 3-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1-[({[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoyl}amino)methyl]urea, 82852-50-4, Imidurea, Germall 115;''N',N-methylenebis[3-[1-(hydroxymethyl)- 2,5-dioxoimidazolidin-4-yl]urea], N-[3-(hydroxymethyl)-2,5-dioxo(1,3-diazolidin-4-yl)]{[({[3-(hydroxymethyl)-2,5 -dioxo(1,3-diazolidin-4-yl)]amino}carbonylamino)methyl]amino}carboxamide, N-[3-(hydroxymethyl)-2,5-dioxo(1,3-diazolidin-4-yl)]{[({N-[3-(hydroxymethyl)-2 ,5-dioxo(1,3-diazolidin-4-yl)]carbamoyl}amino)methyl]amino}carboxamide

ID: 2787

chemical graph of compound 2787



InChIKey: ZCYCZDZSEDMTRV-UHFFFAOYSA-N
SMILES: C1CN(CCN1C2=NC=CC=N2)S(=O)(=O)C3=CC=C(C=C3)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "N Liu" "GW Carlile" "C Pavel" "SM Anjos" "DY Thomas" "D Zhang" "Y Luo" "R Robert" "J Liao"


CID is 703841
synonyms found at PubChem are:
334973-48-7, 4-CHLORO-1-((4-PYRIMIDIN-2-YLPIPERAZINYL)SULFONYL)BENZENE, 2-{4-[(4-chlorophenyl)sulfonyl]piperazino}pyrimidine, 2-[4-(4-chlorobenzenesulfonyl)piperazin-1-yl]pyrimidine, 2-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}pyrimidine, 4-chloro-1-[(4-pyrimidin-2-ylpiperazinyl)sulfonyl]benzene, AC1LDZAN, Cambridge id 7242062, Oprea1_446286, MLS000626846, SCHEMBL5251664, CHEMBL1882279, CTK6H0916, ZINC87272, MolPort-001-545-940, HMS2688D22, CCG-24345, STK441472, AKOS001689286, MCULE-2186472217, MS-7569, KS-0000296C, SMR000299226, ZB003126, ST50927795, AB00040178-01, BRD-K73961382-001-08-1, Z31098000, 2-(4-(4-chlorophenylsulfonyl)piperazin-1-yl)pyrimidine, 2-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]pyrimidine, 2-{4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl}pyrimidine

ID: 2788

chemical graph of compound 2788



InChIKey: ZDASUJMDVPTNTF-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=C(C=C2Br)Br)O)N=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2453
synonyms found at PubChem are:
broxyquinoline, 5,7-Dibromoquinolin-8-ol, 521-74-4, 5,7-Dibromo-8-hydroxyquinoline, 5,7-Dibromo-8-quinolinol, Broxyquinolin, Dibromoxin, Dibromoxine, Dibromoxyquinoline, Broxiquinoline, Dibromoquin, Broxykinolin, Dibromoksin, Paramiba, Brodiar, Colepur, Colipar, Fenilor, 5,7-Dibromooxine, Paramibe, Broxichinolinum, 8-QUINOLINOL, 5,7-DIBROMO-, Brossichinolina, Broxyquinolinum, Dibromohydroxyquinoline, Bromoxine, Brossichinolina [DCIT], Broxyquinoline [INN:DCF], NSC 1810, UNII-UK4C618C8T, Broxyquinolinum [INN-Latin], Broxiquinolina [INN-Spanish], UCB 5055, EINECS 208-317-8, BRN 0153624, AI3-19529, MLS002207288, UK4C618C8T, NSC1810, ZDASUJMDVPTNTF-UHFFFAOYSA-N, NCGC00094815-01, SMR000054336, DSSTox_CID_25849, DSSTox_RID_81171, DSSTox_GSID_45849, Broxiquinolina, CAS-521-74-4, C9H5Br2NO, oxichinolinum, Intensopan, Starogyn (TN), 5,7-Dibromo-oxine, Broxyquinoline (INN), Spectrum_000760, AC1L1DPN, Spectrum2_000944, Spectrum3_000575, Spectrum4_000387, Spectrum5_001463, 8-Quinolinol,7-dibromo-, ACMC-209ky3, Probes1_000369, Probes2_000040, cid_2453, NCIOpen2_009022, 5,7-dibromo-quinolin-8-ol, Oprea1_209922, 8-Quinolinol,5,7-dibromo-, BSPBio_001990, KBioGR_000913, KBioSS_001240, 5-21-03-00290 (Beilstein Handbook Reference), KSC495I8B, DivK1c_000776, SCHEMBL115293, SPECTRUM1500623, SPBio_000908, (5,7-Dibromo-8-quinolinol), AC1Q25I5, CHEMBL223448, ZINC1064, 5,7-dibromoquinolinium-8-olate, DTXSID9045849, BDBM76301, CTK3J5480, HMS502G18, KBio1_000776, KBio2_001240, KBio2_003808, KBio2_006376, KBio3_001490, 5,7-bis(bromanyl)quinolin-8-ol, CHEBI:109543, MolPort-000-721-891, MolPort-000-877-520, NINDS_000776, HMS1921K19, HMS3652L09, Pharmakon1600-01500623, AC1Q7811, HY-B1212, KS-000010LS, NSC-1810, Tox21_111338, ANW-31417, BBL033923, CCG-40333, NSC757389, s4195, SBB058002, STK252144, STK563617, AKOS000119895, AKOS005489208, Tox21_111338_1, AC-4821, CS-4839, MCULE-8850820694, NSC-757389, RTR-033510, TRA0021739, VQ10487, 5,7-Dibromo-8-hydroxyquinoline, 98%, IDI1_000776, NCGC00094815-02, NCGC00094815-03, NCGC00094815-05, AJ-07955, AN-11573, BR-39445, CJ-00027, KB-41347, R343, ZB000234, SBI-0051561.P002, LS-142530, TR-033510, D0208, FT-0619840, ST24029246, ST50308120, D07109, AB00052129-04, AB00052129_07, AB00052129_08, AG-690/03055006, SR-01000872768, SR-01000872768-1, W-105847, Z256709392, 22307-80-8

ID: 2789

chemical graph of compound 2789



InChIKey: ZDPACSAHMZADFZ-UHFFFAOYSA-N
SMILES: COC1=CC(=C(C(=C1)OC)C(=O)CCCN2CCCC2)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 37170
synonyms found at PubChem are:
1-[3-(2,4,6-Trimethoxybenzoyl)propyl]pyrrolidinium chloride, Bufedil, Irrodan, Buflan, Lofton, C17H25NO4.HCl, 4-pyrrolidin-1-ium-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one chloride, EINECS 252-611-9, 1-(3-(2,4,6-Trimethoxybenzoyl)propyl)pyrrolidinium chloride, A-48257, Botamiral (TN), 4-(1-Pyrrolidyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride, 1-BUTANONE, 4-(1-PYRROLIDINYL)-1-(2,4,6-TRIMETHOXYPHENYL)-, HYDROCHLORIDE, Chlorhydrate de (trimethoxy-2-4-6) phenyl-(pyrrolidine-3) propylacetone [French], ACMC-20ap06, AC1L1X6C, Buflomedil hydrochloride (JAN), CTK8C6191, MolPort-006-127-244, KS-00000T6N, AKOS015900393, AN-6964, LS-46879, KB-309885, TC-172077, D07548, A822860, I14-0945, 4-(2,3,4,5-tetrahydropyrrol-1-yl)-1-(2,4,6-trimethoxyphenyl)-1-butanone chloride, 4-(2,3,4,5-tetrahydropyrrol-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one chloride, Buflomedil hydrochloride, Buflomedil HCl, 35543-24-9, Fonzylane, Loftyl, Buflomedil (hydrochloride), UNII-3J944AFS8S, 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride, MLS000028735, 3J944AFS8S, LL 1656, SMR000058803, 4-(pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride, DSSTox_CID_26977, DSSTox_RID_82032, DSSTox_GSID_46977, Q-200766, Buflocit, Irrodan R, SR-01000721839, NCGC00016831-01, CAS-35543-24-9, 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one;hydrochloride, lofton hydrochloride, Prestwick_782, Opera_ID_262, AC1O4WHX, Buflomedil Hydrochloride,(S), MLS001148174, MLS001401458, MLS002222262, MLS006010627, SCHEMBL211907, CHEMBL1715107, DTXSID6046977, AOB5031, MolPort-003-983-416, HMS1569E14, Pharmakon1600-01505992, 55837-25-7 (Parent), BCP13305, HY-B0484, Tox21_110636, Tox21_301435, BG0112, MFCD00078965, NSC759291, s2607, AKOS015962015, Chlorhydrate de (trimethoxy-2-4-6) phenyl-(pyrrolidine-3) propylacetone, Tox21_110636_1, AB03021, API0001779, CCG-100878, CS-2600, DS-9078, NC00128, NSC-759291, VA10440, NCGC00016831-06, NCGC00180961-01, NCGC00256242-01, AC-15509, CPD000058803, H747, SAM001246680, AB2000696, TL8002637, B3647, Buflomedil hydrochloride, analytical standard, FT-0623281, 543B249, C-20428, SR-01000721839-4, SR-01000721839-5, Buflomedil Hydrochloride 1.0 mg/ml in Methanol (as free base), 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one hydrochloride, Buflomedil hydrochloride, European Pharmacopoeia (EP) Reference Standard, Buflomedil for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 2790

chemical graph of compound 2790



InChIKey: ZDWWJLALGOXFJG-NSIMAFANSA-N
SMILES: CC(=O)O[C@H]1C=CC(C2[C@]1(C3CC[C@]4([C@@H](OC(=O)C5C4([C@@]3([C@@H](C2)O)C)O5)C6=COC=C6)C)C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 98042576
synonyms found at PubChem are:
1alpha-ACETOXY--1-DEOXO-7-DEACETYLISOGEDUNIN

ID: 2791

chemical graph of compound 2791



InChIKey: ZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES: C(CC(=O)N)[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5961
synonyms found at PubChem are:
L-glutamine, glutamine, 56-85-9, Levoglutamide, L-(+)-Glutamine, Glutamic acid amide, H-Gln-OH, Stimulina, Cebrogen, glumin, Levoglutamid, Glavamin, glutamic acid 5-amide, L-Glutamide, 2-aminoglutaramic acid, (S)-2,5-Diamino-5-oxopentanoic acid, Miglu-P, Polyglutamine, Saforis, L-2-Aminoglutaramidic acid, L-Glutamic acid gamma-amide, L-Glutamin, Glumin (amino acid), Glutamine (VAN), L-2-Aminoglutaramic acid, (2S)-2-amino-4-carbamoylbutanoic acid, L-Glutamic acid 5-amide, Levoglutamida, Levoglutamidum, Nutrestore, 2-Aminoglutaramic acid, L-, (2S)-2,5-diamino-5-oxopentanoic acid, Levoglutamidum [INN-Latin], Levoglutamida [INN-Spanish], FEMA No. 3684, Levoglutamina, Pentanoic acid, 2,5-diamino-5-oxo-, (S)-, GLUTAMINE, L-, L-Glutamid, 2,5-Diamino-5-oxopentanoic acid, (S)-, AI3-24392, Glutamine [USP], NSC 27421, UNII-0RH81L854J, BRN 1723797, L-Glutaminsaeure-5-amid, EINECS 200-292-1, CHEMBL930, N-(2)-L-alanyl-L-glutamine, AES-14, CHEBI:18050, ZDXPYRJPNDTMRX-VKHMYHEASA-N, d(-)-glutamine, 0RH81L854J, Glutamine (USP), gln, [3H]glutamine, L-gln, [14C]glutamine, [3H]-glutamine, Glutamine (L-Glutamine), Poly(glutamine), [14C]-glutamine, Levoglutamide [DCF:INN], gamma-Glutamine, .gamma.-Glutamine, Glutamine [USAN], GLUTAMINE (D), L-Glutamic acid .gamma.-amide, Glutamine [USAN:USP:INN], laevo-glutamine, CCRIS 9428, 3h-l-glutamine, HSDB 8165, 1wdn, (S)-glutamine, Nutrestore (TN), S(+)Glutamine, Glutamine (INN), L-Glutamine Powder, Cebrogen, Stimulina, L-Glutamine,(S), H-Gln, Aesgen-14, L-Alanyl-L-glutamide, L-Glutamine [JAN], Spectrum_000131, L-Glutamine [JAN], L-Glutaminsaure-5-amid, SpecPlus_000380, L-Glutamine (JP17), GLUTAMINE (L), L-Glutamine, homopolymer, Spectrum2_001377, Spectrum3_001416, Spectrum4_001709, Spectrum5_000418, L-Glutamine, 98.5%, bmse000038, bmse001014, D01JIA, AC1L1LI9, AC1Q4U8A, SCHEMBL7453, Lopac0_000549, BSPBio_003092, GTPL723, KBioGR_002038, KBioSS_000591, 26700-71-0, 4-04-00-03038 (Beilstein Handbook Reference), KSC269S9J, DivK1c_006476, L-Glutamine, 99% 50g, SPECTRUM1500987, S(+)-Glutamic acid 5-amide, SPBio_001334, Glutamine Fuel Mega (Twinlab), L-[3,4-3H(N)]glutamine, AC1Q5J69, GTPL4633, GTPL4634, DTXSID1023100, SCHEMBL19240116, BDBM18121, CTK1G9994, Glutamine Fuel Powder (Twinlab), KBio1_001420, KBio2_000591, KBio2_003159, KBio2_005727, KBio3_002312, MolPort-001-794-053, HMS3261N19, HMS3264C03, Pharmakon1600-01300018, Pharmakon1600-01500987, (S)-2,5-Diamino-5-oxopentanoate, HY-N0390, KS-00000AA5, KS-000010SX, ZINC1532526, (2S)-2-amino-4-carbamoylbutanoate, Tox21_500549, ANW-32592, CCG-38853, EBD968977, MFCD00008044, NSC759628, NSC760081, s1749, AKOS015854078, (S)-2-Amino-4-carbamoyl-butyric acid, AM81759, CS-1947, DB00130, LP00549, MCULE-8718820108, NE10548, NSC-759628, NSC-760081, RP21049, RTC-066534, SDCCGMLS-0066691.P001, L-Glutamine Power (Champion Nutrition), NCGC00093936-01, NCGC00093936-02, NCGC00093936-03, NCGC00093936-04, NCGC00093936-05, NCGC00261234-01, (2S)-2,5-diamino-5-oxo-pentanoic acid, AJ-26776, AS-11765, BP-13284, KB-53212, KB-77550, LS-71898, SBI-0050532.P003, AB0004431, AB1002635, L-Glutamine, BioUltra, >=99.5% (NT), ST2407066, TC-066534, EU-0100549, FT-0627836, G0063, L-Glutamine, SAJ special grade, >=99.0%, C00064, D00015, E-6014, G 3126, M02960, 16575-EP2269996A1, 16575-EP2270004A1, 16575-EP2275412A1, 16575-EP2277861A1, 16575-EP2277876A1, 16575-EP2281563A1, 16575-EP2281815A1, 16575-EP2281824A1, 16575-EP2284157A1, 16575-EP2284171A1, 16575-EP2286812A1, 16575-EP2289876A1, 16575-EP2289883A1, 16575-EP2289892A1, 16575-EP2289893A1, 16575-EP2292611A1, 16575-EP2292614A1, 16575-EP2295055A2, 16575-EP2295401A2, 16575-EP2295411A1, 16575-EP2295416A2, 16575-EP2295417A1, 16575-EP2295429A1, 16575-EP2298312A1, 16575-EP2298748A2, 16575-EP2298780A1, 16575-EP2301533A1, 16575-EP2301940A1, 16575-EP2302382A2, 16575-EP2302383A2, 16575-EP2305640A2, 16575-EP2305652A2, 16575-EP2305663A1, 16575-EP2305688A1, 16575-EP2305689A1, 16575-EP2305695A2, 16575-EP2305696A2, 16575-EP2305697A2, 16575-EP2305698A2, 16575-EP2308844A2, 16575-EP2308845A2, 16575-EP2308846A2, 16575-EP2311453A1, 16575-EP2311806A2, 16575-EP2316459A1, 29474-EP2272827A1, 29474-EP2277867A2, 29474-EP2280003A2, 29474-EP2292088A1, 29474-EP2292611A1, 29474-EP2295410A1, 29474-EP2301939A1, 29474-EP2311842A2, AB00173347-03, AB00173347_04, L-Glutamine, ReagentPlus(R), >=99% (HPLC), L-Glutamine, Vetec(TM) reagent grade, >=99%, 008G044, 141066-EP2269996A1, 141066-EP2292625A1, Glutamine Express (Genetic Evolutionary Nutrition), L-glutamine (oral, short bowel syndrome), Emmaus, 7FBA778C-D6B8-495C-BFE7-1CB8EC4ABEAB, I14-2733, J-521645, Q-100459, BRD-K83896451-001-01-8, Earthlink Science Glutamine Chews Chocolate (Amerifit), F0001-1471, L-Glutamine, certified reference material, TraceCERT(R), Z1250208676, (S)-2,5-Diamino-5-oxopentanoic acid; L-Glutamic acid 5-amide, Glutamine, United States Pharmacopeia (USP) Reference Standard, L-glutamine (topical, chemotherapy-induced mucositis), Aesgen, UNII-5L555N1902 component ZDXPYRJPNDTMRX-VKHMYHEASA-N, L-Glutamine, gamma-irradiated, BioXtra, suitable for cell culture, L-glutamine (oral, sickle cell anemia/sickle beta-0 thalassemia), Emmaus, L-Glutamine, Pharmaceutical Secondary Standard; Certified Reference Material, L-Glutamine Solution 200 mM, 29.23 mg/mL in saline, solution, suitable for cell culture, L-Glutamine solution, 200 mM, Hybri-Max(TM), sterile-filtered, suitable for hybridoma, Proteinogene aminos?uren und stereoisomer D-formen und ihre salze mit gegenionen der WGK 1, 32640-56-5, L-glutamine (oral, sickle cell anemia/sickle beta-0 thalassemia), Emmaus/University of California Los Angeles, L-Glutamine solution, 200 mM, solution, sterile-filtered, BioXtra, suitable for cell culture, L-Glutamine, meets USP testing specifications, cell culture tested, 99.0-101.0%, from non-animal source, L-Glutamine, PharmaGrade, Ajinomoto, USP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture, glum, L-glutamine zwitterion, D01DET, D03BVK, H-Gln-2-Chlorotrityl Resin, CHEBI:58359, (2S)-5-amino-2-ammonio-5-oxopentanoate, CJ-05250, CJ-24200, (2S)-5-amino-2-azaniumyl-5-oxopentanoate

ID: 2792

chemical graph of compound 2792



InChIKey: ZDZDSZQYRBZPNN-UHFFFAOYSA-N
SMILES: C1CNCC2=C1C(=O)NO2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5702253
synonyms found at PubChem are:
THIP hydrochloride, GABOXADOL HYDROCHLORIDE, 85118-33-8, UNII-478RVH3TVD, 478RVH3TVD, 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride, 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HCL, GABOXADOL-HCL, SR-01000075651, EINECS 285-687-7, THIP NIEaNI, THIP HCl, AC1NWAX4, (THIP), D00XNY, MLS002154080, SPECTRUM1503648, CHEMBL1255746, CTK8G3449, AOB5024, DTXSID90234251, MolPort-003-666-496, MolPort-006-141-665, HMS1571C05, Pharmakon1600-01503648, BCP16610, Tox21_501233, BN0520, CCG-39368, NSC759585, AKOS024015212, AKOS027250817, API0007055, LP01233, MCULE-7038235366, NSC-759585, NCGC00094475-01, NCGC00094475-02, NCGC00094475-03, NCGC00094475-04, NCGC00261918-01, AS-53745, BP-12453, KB-71828, SMR000875361, J Med Chem 26: 895 (1983), 85118-33-8 (HCl), B6460, EU-0101233, G0405, T-101, EN300-152453, Gaboxadol hydrochloride, solid, >=98% (HPLC), 4,5,6,7-Tetra-hydroisoxazolo[5,4-c]pyridin-3-ol, SR-01000075651-1, SR-01000075651-3, SR-01000075651-6, SR-01000075651-7, 4,5,6,7-Tetra- hydroisoxazolo[5,4-c]pyridin-3-ol, 4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol, 4,5,6,7-EACaOidouble daggerfsso[5,4-c]ssAa currency-3- (1/4) NIEaNI, 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one hydrochloride, SCHEMBL567225

ID: 2793

chemical graph of compound 2793



InChIKey: ZEASWHWETFMWCV-UHFFFAOYSA-N
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=O)C(=C4C(=C3)C(=CC(=C4O)O)C5C(CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)OC(=O)C8=CC(=C(C(=C8)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3589471
synonyms found at PubChem are:
CHEMBL1451483, Theaflavin 3,3'-di-O-gallate, AC1MSSNV, Theaflavin-di-O-gallate, BDBM50335560, NCGC00095721-01, [2-[1-[5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,5-trihydroxy-6-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, 2,2''-(3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulene-1,8-diyl)bis(5,7-dihydroxychroman-3,2-diyl)bis(3,4,5-trihydroxybenzoate), 2-(8-{5,7-dihydroxy-3-[(3,4,5-trihydroxyphenyl)carbonyloxy]-3,4-dihydro-2H-1-benzopyran-2-yl}-3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulen-1-yl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate

ID: 2794

chemical graph of compound 2794



InChIKey: ZEEDZJJOWWIIFH-UHFFFAOYSA-N
SMILES: COC1=CC=CC2=CC(=C(C(=C2C1=O)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 234873
synonyms found at PubChem are:
Purpurogallin tetramethyl ether, CHEMBL134871, 6273-57-0, 2,3,4,6-Tetramethoxy-benzocyclohepten-5-one, 2,3,4,6-tetramethoxy-5H-benzo[7]annulen-5-one, NSC52570, Spectrum_001940, SpecPlus_000490, Spectrum5_001688, ChemDiv2_001976, AC1L5T5B, AC1Q6JK0, Oprea1_001909, KBioSS_002492, MLS001048925, DivK1c_006586, 5h-benzocyclohepten-5-one, 2,3,4,6-tetramethoxy-, SCHEMBL12171162, CTK5B5808, KBio1_001530, KBio2_002485, KBio2_005053, KBio2_007621, ZINC56820, DTXSID80284104, MolPort-000-516-171, HMS1374J18, HMS2268J06, NSC35623, BDBM50133358, NSC-35623, NSC-52570, STK235005, AKOS000525526, MCULE-2860542554, BAS 00160614, SMR000387113, 2,3,4,6-tetramethoxybenzo[7]annulen-5-one, ST50167780, 2,7,8,9-tetramethoxybenzo[a][7]annulen-1-one, AB00052896-09, 2,3,4,6-Tetramethoxy-5H-benzocyclohepten-5-one, SR-01000323883, 5H-Benzocyclohepten-5-one,2,3,4,6-tetramethoxy-, SR-01000323883-1, BRD-K78848902-001-07-8

ID: 2795

chemical graph of compound 2795



InChIKey: ZEFNOZRLAWVAQF-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1C(=O)N)[N+](=O)[O-])[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3092
synonyms found at PubChem are:
dinitolmide, 2-Methyl-3,5-dinitrobenzamide, 148-01-6, Zoalene, Coccidot, Zoamix, 3,5-Dinitro-o-toluamide, Coccidine A, Dinitolmida, Benzamide, 2-methyl-3,5-dinitro-, Zoalene [ANSI], Dinitolmidum, Salcostat, Dinitrotoluamide, Dinitolmide [INN:BAN], Dinitro-o-toluamide, Methyldinitrobenzamide, Caswell No. 932, UNII-AOX68RY4TV, Dinitolmidum [INN-Latin], Dinitolmida [INN-Spanish], o-Toluamide, 3,5-dinitro-, HSDB 7192, 3,5-Dinitro Toluamide, EINECS 205-706-4, AOX68RY4TV, EPA Pesticide Chemical Code 037510, BRN 1990738, 3,5-Dinitro-2-methylbenzamide, 2-methyl-3,5-dinitro-benzamide, NCGC00094985-01, DSSTox_CID_22521, DSSTox_RID_80047, DSSTox_GSID_42521, W-108109, CAS-148-01-6, SR-01000872611, Bornylformiat, Abilene, Coccidin, Coccidine, Zamix, Whitsyn T, Dinitolmide (INN), Dinitolmide (Zoalene), Spectrum_001272, Dinitolmide, BAN, INN, Spectrum2_000677, Spectrum3_001545, Spectrum4_000732, Spectrum5_001231, Dinitrotoluamide (Related), AC1L1F5K, SCHEMBL43712, 3,5-Dinitro-ortho-toluamide, BSPBio_002990, KBioGR_001024, KBioSS_001752, 3-09-00-02316 (Beilstein Handbook Reference), MLS002695903, DivK1c_000214, SPECTRUM1503036, SPBio_000773, CHEMBL472565, Methyldinitrobenzamide (Related), DTXSID6042521, CTK5I2357, D.O.T. (TN), HMS500K16, KBio1_000214, KBio2_001752, KBio2_004320, KBio2_006888, KBio3_002490, 3,5-Dinitro-o-toluamide, 98%, MolPort-001-526-950, NINDS_000214, ZEFNOZRLAWVAQF-UHFFFAOYSA-N, HMS1922A07, HMS3089A22, HMS3652K20, Pharmakon1600-01503036, HY-B1004, ZERO/002890, ZINC2040950, Tox21_111374, Tox21_301320, AN-808, BBL003876, CCG-40029, NSC758213, s4141, SBB002442, STK395739, 2-Methyl-3,5-dinitrobenzamide, 9CI, AKOS003282656, Tox21_111374_1, CS-4501, MCULE-1522724975, NSC-758213, IDI1_000214, NCGC00094985-02, NCGC00094985-03, NCGC00094985-05, NCGC00255914-01, AC-20062, AJ-33257, CC-11337, CJ-32448, P425, SC-22566, SMR001253784, SBI-0051752.P002, AX8006191, DB-021326, KB-173642, LS-154003, ST4083911, FT-0614722, T7414, D07857, EN300-199771, AB00052301_04, Dinitolmide, VETRANAL(TM), analytical standard, 148M016, C-12747, I14-0951, SR-01000872611-2, SR-01000872611-3, BRD-K93240442-001-02-7, BRD-K93240442-001-04-3

ID: 2796

chemical graph of compound 2796



InChIKey: ZEGDFCCYTFPECB-UHFFFAOYSA-N
SMILES: COC1=C(C(=O)C2=CC=CC=C2C1=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3136
synonyms found at PubChem are:
dmnq, 2,3-Dimethoxy-1,4-naphthoquinone, 6956-96-3, DiMeNQ, 2,3-dimethoxynaphthalene-1,4-dione, NSC 69355, 1,4-Naphthalenedione, 2,3-dimethoxy-, CHEBI:64215, ZEGDFCCYTFPECB-UHFFFAOYSA-N, 2,3-dimethoxy-1,4-naphthalenedione, IN1354, 2,3-Dimethoxynaphthoquinone, AC1Q6JAE, Lopac-D-5439, NCIOpen2_003296, Lopac0_000399, MLS002153320, SCHEMBL571557, 2,3-Dimethoxynaphthoquinone #, AC1L1F92, CHEMBL402468, DTXSID8040935, CTK5D0467, MolPort-002-510-862, HMS3261O19, ZINC518909, 2,3-Dimethoxy[1,4]naphthoquinone, NSC69355, Tox21_500399, NSC-69355, 1,4-Naphthalenedione,2,3-dimethoxy-, AKOS022506394, CCG-204492, LP00399, MCULE-3113555147, NCGC00015348-01, NCGC00015348-02, NCGC00015348-03, NCGC00015348-04, NCGC00015348-05, NCGC00093826-01, NCGC00093826-02, NCGC00261084-01, SMR001230733, EU-0100399, D 5439, SR-01000075819, 2,3-Dimethoxy-1,4-naphthoquinone, >=99%, solid, SR-01000075819-1

ID: 2797

chemical graph of compound 2797



InChIKey: ZEKALTOSWFXTCN-UHFFFAOYSA-N
SMILES: CC1(C2CC1C(=C)C(C2)N)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3612673
synonyms found at PubChem are:
3-AMINO-beta-PINENE, KBio3_002370, Spectrum_000680, SpecPlus_000226, AC1MU4OJ, Spectrum2_001903, Spectrum3_001275, Spectrum4_001456, Spectrum5_000071, BSPBio_002870, KBioGR_001971, KBioSS_001160, DivK1c_006322, SPBio_001866, SCHEMBL4272806, CHEMBL3039430, KBio1_001266, KBio2_001160, KBio2_003728, KBio2_006296, CHEBI:103983, SDCCGMLS-0066529.P001, NCGC00178418-01, BRD-A31576716-003-02-6, BRD-A31576716-003-03-4, 6,6-dimethyl-4-methylidenebicyclo[3.1.1]heptan-3-amine

ID: 2798

chemical graph of compound 2798



InChIKey: ZEMGGZBWXRYJHK-UHFFFAOYSA-N
SMILES: C1=CNC(=S)NC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1586
synonyms found at PubChem are:
2-thiouracil, Thiouracil, 141-90-2, 4-Hydroxy-2-mercaptopyrimidine, Antagothyroid, Antagothyroil, Deracil, Nobilen, 2-thioxo-2,3-dihydropyrimidin-4(1H)-one, 2-Mercapto-4-hydroxypyrimidine, 2-Mercapto-4-pyrimidone, 2-Mercapto-4-pyrimidinol, 2-Mercaptopyrimidin-4-ol, 6-Thiouracil, 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-, 4-Hydroxy-2-pyrimidinethiol, 4-Pyrimidinol, 2-mercapto-, 2-sulfanylpyrimidin-4-ol, Uracil, 2-thio-, 2-TU, 6-Hydroxy-2-mercaptopyrimidine, 2,3-Dihydro-2-thioxo-4(1H)-pyrimidinone, 2-Thio-1,3-pyrimidin-4-one, 80275-68-9, Tiouracyl [Polish], 2-Thiouracil (VAN), 2-Thio-4-oxypyrimidine, 2-Thio-6-oxypyrimidine, 2-Thio-2,4-(1H,3H)-pyrimidinedione, C4H4N2OS, UNII-59X161SCYL, NSC 19473, CCRIS 587, 2-Thio-4-oxo-1,3-pyrimidine, 2-Mercapto-4(1H)-pyrimidinone, HSDB 2954, NCI-C01490, 4-Hydroxy-2(1H)-pyrimidinethione, 2-Mercaptopyrimid-4-one, EINECS 205-508-8, TU, 2-Mercapto-pyrimidin-4-ol, 4-Hydroxypyrimidine-2-thiol, 2-thioxo-1H-pyrimidin-4-one, 2-Thioxo-2,3-dihydro-1H-pyrimidin-4-one, AI3-25474, 59X161SCYL, 125220-28-2, 156-82-1, 2-sulfanylpyrimidin-4(3H)-one, 2-thio-uracil, CHEBI:348530, ZEMGGZBWXRYJHK-UHFFFAOYSA-N, 4-hydroxypyrimidine-2(1H)-thione, 2-sulfanylidene-1H-pyrimidin-4-one, 124700-71-6, 126160-72-3, NCGC00095088-01, 4(1H)-Pyrimidinone, 2-mercapto- (9CI), 2(1H)-Pyrimidinethione, 4-hydroxy- (9CI), DSSTox_CID_1347, DSSTox_RID_76100, DSSTox_GSID_21347, 2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one, Tiouracyl, 124700-72-7, CAS-141-90-2, 2-thio-4-pyrimidone, Spectrum_001652, ACMC-1BSCK, SpecPlus_000746, 4-hydroxypyrimidinethione, AC1LOT6W, Spectrum3_000979, Spectrum4_001104, Spectrum5_001378, WLN: T6MYMVJ BUS, 2-Thiouracil, >=99%, 4-hydroxy-2-thiopyrimidine, SCHEMBL9172, Uracil, 2-thio- (VAN), 2-Sulfanyl-4-pyrimidinol #, 6-hydroxypyrimidine-2-thione, BSPBio_002617, KBioGR_001548, KBioSS_002132, KSC490Q8R, DivK1c_000104, DivK1c_006842, SPECTRUM1503973, CHEMBL345768, DTXSID4021347, CTK3J0888, CTK8A0606, CTK8G7241, CTK8G7242, CTK8G7299, CTK8G7379, HMS500F06, KBio1_000104, KBio1_001786, KBio2_002132, KBio2_004700, KBio2_007268, KBio3_001837, KS-00000IUN, MolPort-001-762-546, MolPort-001-785-696, MolPort-004-758-315, MolPort-004-758-322, NINDS_000104, HMS1922O08, HMS3651F22, Pharmakon1600-01503973, 4(3H)-Pyrimidinone, 2-mercapto-, 4-?Hydroxy-?2-?mercaptopyrimidine, HY-B0503, NSC19473, ZINC5127810, Tox21_111418, Tox21_202418, Tox21_302955, Uracil, 2-thio- (VAN) (8CI), 4-Pyrimidinol, 2-mercapto- (9CI), ANW-20654, BBL005253, BBL013523, BBL018366, BBL027996, CCG-39926, KM2026, MFCD00006039, NSC-19473, NSC758660, s3100, SBB007592, STL011919, STL134904, STL168055, STL185506, AKOS000119226, AKOS002303247, AKOS005366847, AKOS022061520, Tox21_111418_1, AM84374, CS-2704, GS-6727, LS-7724, LS40673, MCULE-8341460410, NSC-758660, RP19789, 2-sulfanyl-3,4-dihydropyrimidin-4-one, IDI1_000104, SMP1_000293, NCGC00095088-02, NCGC00095088-03, NCGC00095088-05, NCGC00249223-01, NCGC00256423-01, NCGC00259967-01, AJ-53209, AN-23215, BR-41390, CJ-12446, KB-87279, SC-46212, ST075010, 2,3-dihydro-2-thioxo-4(1h)-pyrimidinon, 2,3-dihydro-2-thioxopyrimidin-4(1h)-one, SBI-0051878.P002, 4(3H)-Pyrimidinone, 2-mercapto- (9CI), DB-004877, DB-028206, KB-173427, FT-0613452, FT-0725874, T7366, 2(1H)-Pyrimidinethione, 6-hydroxy- (9CI), 2-Thiouracil, Vetec(TM) reagent grade, 99%, A-8511, C19304, T-3800, T-3808, 16426-EP2272832A1, 16426-EP2281563A1, 16426-EP2316459A1, 16432-EP2281563A1, 16432-EP2316459A1, 48873-EP2287157A1, 48873-EP2311841A1, AB00052397_02, AB00171996_02, 2-Thiouracil, VETRANAL(TM), analytical standard, SR-01000872748, I09-1091, SR-01000872748-1, 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- (9CI), Z56771015, F0001-0490, InChI=1/C4H4N2OS/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8, 107646-88-8, 107646-89-9, 4401-53-0, 4401-54-1, TUL

ID: 2799

chemical graph of compound 2799



InChIKey: ZEMIJUDPLILVNQ-ZXFNITATSA-N
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)OCOC(=O)C(C)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 33478
synonyms found at PubChem are:
Pivampicillin, Pivaloylampicillin, Pivampicilina, Pivampicilline, Pivampicillinum, Pivaloyloxymethyl ampicillinate, Ampicillin pivaloyloxymethyl ester, 33817-20-8, Pivampicilina [INN-Spanish], Pivampicilline [INN-French], Pivampicillinum [INN-Latin], Pondocillin, Pivampicillin [INN:BAN], MK 191, Ampicillin Pivaloyl Ester, UNII-0HLM346LL7, Pondocillin (TN), Berocillin, Pivampicillin Monohydrochloride, Pivampicillin (INN), EINECS 251-688-6, 0HLM346LL7, CHEBI:8255, C22H29N3O6S, DSSTox_CID_25459, DSSTox_RID_80890, DSSTox_GSID_45459, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-(2alpha,5alpha,6beta(S*)))-, [(2,2-dimethylpropanoyl)oxy]methyl 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate, 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-, hydroxymethyl ester, pivalate (ester), D-(-)-, NCGC00016823-01, CAS-33817-20-8, Prestwick0_001009, Prestwick1_001009, Prestwick2_001009, Prestwick3_001009, D04KAQ, AC1L1PP5, SCHEMBL34182, BSPBio_001137, SPBio_003018, BPBio1_001251, CHEMBL3182343, DTXSID1045459, HMS1571I19, HMS2098I19, HMS3715I19, Tox21_110631, ZINC34967244, 26309-95-5 (mono-hydrochloride), Tox21_110631_1, CCG-221009, DB01604, NCGC00179290-01, NCGC00179290-03, AN-16708, CC-33832, LS-149724, AB00513999, FT-0773781, D08396, C-23814, SR-01000872693, SR-01000872693-1, (2S,5R,6R)-pivaloyloxymethyl 6-((R)-2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, [(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carbonyloxy]methyl 2,2-dimethylpropanoate, {[(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-yl]carbonyloxy}methyl 2,2-dimethylpropanoate, 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

ID: 2800

chemical graph of compound 2800



InChIKey: ZESRJSPZRDMNHY-YFWFAHHUSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)CO)CCC4=CC(=O)CC[C@]34C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6166
synonyms found at PubChem are:
Desoxycortone, 21-Hydroxyprogesterone, desoxycorticosterone, 11-Deoxycorticosterone, Deoxycorticosterone, Cortexone, Deoxycortone, 64-85-7, 11-Desoxycorticosterone, Reichstein's substance Q, 4-Pregnen-21-ol-3,20-dione, Desossicortone, Desoxicortonum, Kendall's desoxy compound B, 11-Dehydroxycorticosterone, Corticosterone, 11-deoxy-, 21-HYDROXYPREGN-4-ENE-3,20-DIONE, 21-Hydroxy-4-pregnene-3,20-dione, Desoxycorticosteronum, Progesterone, 21-hydroxy-, DOC, Pregn-4-ene-3,20-dione, 21-hydroxy-, 1,2(3H)-Deoxycorticosterone, Desossicortone [DCIT], 11-Deoxy Corticosterone, Desoxycortonum [INN-Latin], NSC 11319, Desoxicortona [INN-Spanish], UNII-40GP35YQ49, EINECS 200-596-4, MLS000028537, CHEBI:16973, ZESRJSPZRDMNHY-YFWFAHHUSA-N, 40GP35YQ49, 21-Hydroxy-3,20-dioxopregn-4-ene, SMR000058340, DSSTox_CID_25254, DSSTox_RID_80776, DSSTox_GSID_45254, (8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, Desoxicortona, [4-14C]-11-deoxycorticosterone, 1CA, Desoxycortone [INN:BAN], Reichstein Q, Desoxycorticosteron, CAS-64-85-7, NCGC00016292-01, 11-Dcortic, Desoxycortone (INN), DOCA (Salt/Mix), Opera_ID_581, 11-deoxy-Corticosterone, 21-hydroxy-Progesterone, AC1L1LXL, Prestwick0_000957, Prestwick1_000957, Prestwick2_000957, Prestwick3_000957, Kendalls desoxy compound B, bmse000535, D04SQY, SCHEMBL4065, CHEMBL1498, BSPBio_000954, MLS001076270, ARONIS24592, SPBio_003103, BDBM8582, BPBio1_001050, GTPL2871, DTXSID0045254, hydroxy-4-pregnene-3,20-dione, 4-pregnene-3,20-dione-21-ol, HMS1570P16, HMS2097P16, HMS2235G07, HMS3714P16, D4-Pregnene-21-ol-3,20-dione, ZINC3833823, Tox21_110356, Tox21_302402, CMC_13409, delta4-Pregnen-21-ol-3,20-dione, LMST02030087, MFCD00003661, Delta4-Pregnene-21-ol-3,20-dione, 21-Hydroxy-D4-pregnane-3,20-dione, 21-Hydroxy-D4-pregnene-3,20-dione, AKOS005111365, Tox21_110356_1, 21-hydroxy-Pregn-4-ene-3,20-dione, CCG-220957, 21-Hydroxypregn-4-ene-3,20-dione #, NCGC00021304-03, NCGC00021304-05, NCGC00256184-01, 21-Hydroxy-Delta4-pregnane-3,20-dione, 21-Hydroxy-Delta4-pregnene-3,20-dione, 21-Hydroxyprogesterone, >=97% (HPLC), BC226378, LS-59472, N730, AB00490029, C03205, D07792, 99527-EP2270011A1, 99527-EP2301931A1, 003H661, 139372-EP2270008A1, 139372-EP2292617A1, SR-01000003106, SR-01000003106-2, W-104814, BRD-K98521173-001-03-8, Kendall inverted exclamation mark s desoxy compound B, BD5D7BC9-0CD8-404E-9BA0-F670962012F8, inverted exclamation mark(R)Reichstein Q inverted exclamation mark, (1S,2R,10S,11S,14S,15S)-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-6-en-5-one

ID: 2801

chemical graph of compound 2801



InChIKey: ZFLWDHHVRRZMEI-UHFFFAOYSA-N
SMILES: CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2303
synonyms found at PubChem are:
71145-03-4, Bay K 8644, (+/-)-BAY K 8644, BAY-K-8644, BayK8644, methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate, Bay K8644, MLS000028858, 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester, C16H15F3N2O4, (+/-)-Bay K8644, R(+)-BAY K 8644, SMR000058424, Methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate, 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2&prime;-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid Methyl Ester, SR-01000075305, CHEMBL283013, 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, Bay-K-8644, (+-)-Isomer, Opera_ID_789, AC1L1DDI, D01RAD, AC1Q5A9R, CBiol_001744, Lopac0_000186, BSPBio_001578, MLS001148586, MLS002153190, SCHEMBL133106, (y)-Bay K 8644, GTPL2511, CHEMBL1322959, SCHEMBL14612812, BAYK 8644, CHEBI:34555, CTK2H8725, CHEBI:131345, MolPort-003-983-521, ZFLWDHHVRRZMEI-UHFFFAOYSA-N, BAY-R 4407, BAY-R 5417, Bio1_000030, Bio1_000519, Bio1_001008, HMS1791O20, HMS1989O20, HMS2231A11, HMS2232B12, HMS3260F13, HMS3268C13, HMS3370M19, HMS3371N20, HMS3402O20, (?)-Bay K 8644, AOB33740, BCP15942, BCP23924, BCP24795, KS-000018EV, R-(+)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester, ( )-Bay K 8644, Tox21_500186, BDBM50035800, BN0100, CA-410, HSCI1_000381, IN2054, s7924, STL213543, AKOS015858973, CCG-204281, LP00186, MCULE-8564076696, 3-pyridine carboxylic acid methyl ester, ( inverted question mark)-Bay K 8644, NCGC00015124-03, NCGC00015124-04, NCGC00015124-05, NCGC00015124-06, NCGC00015124-07, NCGC00015124-08, NCGC00025209-02, NCGC00025209-03, NCGC00025209-04, NCGC00025209-05, NCGC00025209-06, NCGC00260871-01, AS-16745, KB-71094, KB-74868, KB-74869, SMR001230679, (+/-)-BAY K-8644, (+/-)-BAY-K-8644, NCG-C00025209-02, LS-178346, LS-184293, TX-011326, AM20080536, B-112, EU-0100186, FT-0742944, (+/-)-Bay K8644, calcium channel agonist, C13758, SR-01000075305-1, SR-01000075305-3, BRD-A05457250-001-03-5, BRD-A05457250-001-04-3, 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)-phenyl]-, (S)-2,6-Dimethyl-5-nitro-4-(2-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid methyl ester, 1,4-Dihydro-2,6-dimethyl-5-nitro-4- [2-(trifluoromethyl)-phenyl]-3-pyridine- carboxylic acid methyl ester, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylic acid methyl este, 1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylic acid methyl ester, 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)-phenyl]-3-pyridine-carboxylic acid methyl ester, 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester, 3-Pyridinecarboxylic acid,1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-,methyl ester, 93468-89-4

ID: 2802

chemical graph of compound 2802



InChIKey: ZFSPFXJSEHCTTR-UHFFFAOYSA-N
SMILES: C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 207841
synonyms found at PubChem are:
Procyclidine hydrochloride, 1508-76-5, Procyclidine HCl, Tricyclamol hydrochloride, (-)-Tricyclamol iodide, Procyclidine (hydrochloride), (-)-Procyclidine methyl iodide, EINECS 216-141-8, C19H29NO.HCl, MLS000028556, Procyclidine hydrochloride [USP], alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride, 30953-84-5, 1-cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol hydrochloride, SMR000058821, (-)-1-(3-Cyclohexyl-3-hydroxy-3-phenylpropyl)-1-methylpyrrolidinium iodide, DSSTox_CID_25357, DSSTox_RID_80823, Pyrrolidinium, 1-(3-cyclohexyl-3-hydroxy-3-phenylpropyl)-1-methyl-, iodide, (-)-, DSSTox_GSID_45357, alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol, Procyclidine hydrochloride (USP), 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl-, hydrochloride, 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl-, monohydrochloride, CHEBI:8449, 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride, SR-01000000095, Procyclidine hydrochloride [USAN], Kemadrin (TN), Prestwick_125, 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride, 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol hydrochloride, Opera_ID_270, AC1L4JJJ, NCGC00016585-01, CAS-1508-76-5, CHEMBL1761, MLS001076129, MLS002222170, SCHEMBL121684, SPECTRUM1500507, DTXSID8045357, REGID_for_CID_207841, CTK4G6182, HMS1570J09, HMS1920L10, Pharmakon1600-01500507, HY-B1487, Tox21_110508, CCG-39236, NSC757293, AKOS030575627, Tox21_110508_1, API0025896, CS-5893, NC00585, NSC-757293, NCGC00018186-07, NCGC00094769-01, NCGC00094769-02, NCGC00094769-03, NCGC00094769-04, AN-19714, CPD000058821, SAM002564231, LS-138143, LS-138318, FT-0674043, Y0487, D00782, 508P765, J-008753, SR-01000000095-4, ( inverted exclamation markA)-Procyclidine hydrochloride, (R)-1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol hydrochloride, Procyclidine hydrochloride, United States Pharmacopeia (USP) Reference Standard, (+-)-Procyclidine hydrochloride, AC1LCWH4, 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol; hydron; chloride

ID: 2803

chemical graph of compound 2803



InChIKey: ZFWVWZODBGTOIL-UHFFFAOYSA-N
SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 24351
synonyms found at PubChem are:
Propionylpromazine hydrochloride, PROPIOPROMAZINE HYDROCHLORIDE, 7681-67-6, UNII-U0BND6SD2I, U0BND6SD2I, DSSTox_CID_25187, DSSTox_RID_80734, DSSTox_GSID_45187, MLS000859893, CAS-7681-67-6, NCGC00015838-03, SMR000326755, Tranvet, SR-01000076080, Propionylpromazine HCl, AC1L2NDK, Propionpromazine Hydrochloride, propionylpromazinehydrochloride, SCHEMBL1321671, CHEMBL1256661, DTXSID4045187, Propionylpromazine, Hydrochloride, CTK8G2607, Tox21_110240, Tox21_500992, 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)-1-propanone, MFCD01941563, Tox21_110240_1, API0000769, CCG-222296, CS-W020886, LP00992, 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)-1-propanone monohydrochloride, 1-Propanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-, monohydrochloride, NCGC00015838-06, NCGC00094289-01, NCGC00261677-01, LS-87165, EU-0100992, FT-0674078, P 7780, SR-01000076080-1, 10-(3-Dimethylaminopropyl)-2-propionylphenothiazine Hydrochloride, 2-Propionyl-10-(3-dimethylaminopropyl)phenothiazine Hydrochloride, Propionylpromazine hydrochloride, VETRANAL(TM), analytical standard, 1-[10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]-1-propanone Hydrochloride, 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one hydrochloride, 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one;hydrochloride, AC1Q1STM

ID: 2804

chemical graph of compound 2804



InChIKey: ZFXYFBGIUFBOJW-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC=N2

biological descriptors:

CFTR relevance: Nonspecific phosphodiesterase inhibitor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

"PC Chao" "KL Hamilton"


CID is 2153
synonyms found at PubChem are:
theophylline, 58-55-9, 1,3-Dimethylxanthine, Elixophyllin, Theophyllin, Theolair, Nuelin, Theophylline anhydrous, Respbid, Theocin, Theo-dur, Elixophylline, Pseudotheophylline, Lanophyllin, Theovent, Uniphyl, Slo-phyllin, Accurbron, Armophylline, Bronkodyl, Doraphyllin, Liquophylline, Maphylline, Medaphyllin, Optiphyllin, Parkophyllin, Synophylate, Teofyllamin, Theacitin, Theocontin, Uniphyllin, Xantivent, Aerolate, Elixicon, Solosin, Teolair, Theobid, Theofol, Theograd, Theolix, Elixex, Acet-theocin, Slo-bid, Theophyl-225, Aerolate III, Duraphyl, Euphylong, Sustaire, Austyn, Somophyllin-t, Constant-T, Teofilina, Theochron, Xanthium, Asmax, Quibron T/SR, Theal tablets, Somophyllin-DF, Bronkodyl SR, Theoclair-SR, Theoclear LA, Spophyllin retard, Choledyl SA, Quibron-T, Theoclear 80, Aquaphyllin, Aerobin, Tefamin, Theo-11, Theodur, Theopek, Theospan, Theostat 80, Synophylate-L.A. Cenules, Theophylline, anhydrous, Theo-24, Theo-Dur-Sprinkle, LaBID, Cetraphylline, Chronophyllin, Diffumal, Duraphyllin, Elixomin, Etheophyl, Theolixir, Theophyl, Theophyline, Theostat, Theodel, Unifyl, LASMA, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, Elixophyllin SR, Theophylline-SR, Pro-vent, Somophyllin-CRT, Constant T, Aerolate SR, Theolair-SR, Theophyl-SR, 1,3-dimethyl-7H-purine-2,6-dione, Theona P, Uni-Dur, Theoclear-80, Quibron-T/SR, T-Phyl, Euphylline, Theoclear-200, Teofilina [Polish], Labophylline, Uniphylline, Afonilm, Bilordyl, Bronkotabs, Egifilin, Mudrane, Physpan, Pulmidur, Teonova, Theokin, Theonite, Asbron, Hylate, Afonilum Retard, Somophyllin T, Theo-Organidin, GS 2591A, Nuelin SA, 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione, Bronchodid Duracap, Theobid Jr., Theoclear L.A.-130, Uniphyllin continus, Quibron T-SR, Xanthine, 1,3-dimethyl-, Dimethylxanthine, NSC 2066, Teocen 200, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, X 115, Bronchoretard, Theo 24, Afonilum, Asmalix, Quadrinal, Respicur, Talotren, Teosona, Theoclear, Theodrip, Theoplus, Theotard, Unilong, Respid, Tesona, Pulmo-Timelets, Theobid Duracap, Elixophyllin(e), Somophyllin CRT, Quibron T, Theo-Nite, Theal tabl., Theodur Dry Syrup, Nuelin S.A, Telb-DS, Theo-DS, Theolair (TN), 1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, Bronchoparat, Elixophyllin (TN), Uniphyl (TN), Quibron-t (TN), SloPhyllin, SomophyllinT, UNII-0I55128JYK, ConstantT, Theodur G (TN), CCRIS 4729, Slo Phyllin, theo von ct, HSDB 3399, Theo Dur, Quibron TSR, ct, theo von, von ct, theo, Purine-2,6(1H,3H)-dione, 1,3-dimethyl-, Quibron T SR, EINECS 200-385-7, Nuelin S.A., CHEMBL190, Theo-24 (TN), Theo24, Theophylline [USP], C7H8N4O2, THEOBID JR, AI3-50216, MLS000069390, CHEBI:28177, ZFXYFBGIUFBOJW-UHFFFAOYSA-N, 0I55128JYK, 2,6-Dihydroxy-1,3-dimethylpurine, Euphyllin, 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine, 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, Theodur G, NCGC00018117-07, NCGC00018117-17, SMR000058537, DSSTox_CID_1336, 1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, Aminophylline dihydrate, DSSTox_RID_76090, DSSTox_GSID_21336, CAS-58-55-9, 111079-49-3, 75448-53-2, Theoconfin Continuous, Glycine Theophyllinate, 1,3 Dimethylxanthine, 1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione, SR-01000075195, throphylline, Telbans, Physpa, Telbans DrySyrup, Unicontin CR, 4eoh, Aescin-IIA, Telbans Dry Syrup, PubChem9695, Theophylline 454g, theophylline solu-tion, component of Primatene, Theophylline-[8-3H, Xanthine,3-dimethyl-, Opera_ID_76, Spectrum_001038, Theophylline (JP15), Theophylline (JP17), 2a3a, Theophylline aminoacetate, Theophylline (anhydrous), Prestwick0_000820, Prestwick0_000873, Prestwick1_000820, Prestwick1_000873, Prestwick2_000820, Prestwick2_000873, Prestwick3_000820, Prestwick3_000873, Spectrum2_000842, Spectrum3_000672, Spectrum4_000353, Spectrum5_001232, 8-(2-Furyl)theophylline, D0F8RA, UPCMLD-DP123, component of Theo-Organidin, EC 200-385-7, AC1L1D1F, SCHEMBL4915, Theophylline Anhydrous,(S), Theophylline Anhydrous, USP, Lopac0_000014, BSPBio_000719, BSPBio_000945, BSPBio_002363, component of Dicurin Procaine, GTPL413, KBioGR_000785, KBioSS_001518, 49746-06-7, KSC491S8L, MLS002152943, MLS002153487, MLS004491910, MLS006011970, ARONIS25346, BIDD:ER0557, BIDD:GT0151, DivK1c_000203, SPECTRUM1500568, SPBio_000823, SPBio_002640, SPBio_002866, BPBio1_000791, BPBio1_001041, SCHEMBL8312163, component of Tedral (Salt/Mix), DTXSID5021336, UPCMLD-DP123:001, BCBcMAP01_000071, BDBM10847, BDBM82053, component of Quibron (Salt/Mix), CTK3J1985, HMS500K05, KBio1_000203, KBio2_001518, KBio2_004086, KBio2_006654, KBio3_001583, NSC2066, component of Hecadrol (Salt/Mix), MolPort-001-002-058, MolPort-001-737-342, NINDS_000203, HMS1921E03, HMS2089A06, HMS2092M05, HMS2233E16, HMS3259O06, HMS3369N14, Pharmakon1600-01500568, component of Primatene (Salt/Mix), component of Bronkotabs (Salt/Mix), HY-B0809, NSC-2066, Theophylline 1.0 mg/ml in Methanol, Theophylline, >=99.0% (HPLC), Tox21_110827, Tox21_202375, Tox21_300028, BBL023514, CCG-20301, LS-241, MFCD00079619, NSC757346, PDSP1_001018, PDSP1_001234, PDSP2_001002, PDSP2_001218, STK397040, Theophylline (1,3-dimethylxanthine), ZINC18043251, AKOS000120961, AKOS005434016, component of Quibron Plus (Salt/Mix), Tox21_110827_1, component of Quibron-T/SR (Salt/Mix), component of Theo-organdin (Salt/Mix), component of Theolair plus (Salt/Mix), CS-4158, DB00277, MCULE-8236489917, NC00542, NE11194, NSC-757346, Purine-2,3H)-dione, 1,3-dimethyl-, RP24142, SDCCGMLS-0066620.P001, component of Theo-Organidin (Salt/Mix), IDI1_000203, KS-000010T0, KS-0000477R, SMP1_000291, component of Slo-phyllin GG (Salt/Mix), NCGC00018117-01, NCGC00018117-02, NCGC00018117-03, NCGC00018117-04, NCGC00018117-05, NCGC00018117-06, NCGC00018117-08, NCGC00018117-09, NCGC00018117-10, NCGC00018117-11, NCGC00018117-12, NCGC00018117-13, NCGC00018117-14, NCGC00018117-15, NCGC00018117-16, NCGC00018117-18, NCGC00018117-19, NCGC00018117-20, NCGC00018117-23, NCGC00022112-03, NCGC00022112-04, NCGC00022112-05, NCGC00022112-07, NCGC00022112-08, NCGC00022112-09, NCGC00022112-10, NCGC00022112-11, NCGC00022112-12, NCGC00254040-01, NCGC00259924-01, WLN: T56 BM DN FNVNVJ F1 H1, AC-20328, AN-23602, component of Dicurin Procaine (Salt/Mix), CPD000058537, NCI60_001736, SAM002554935, SC-05534, SC-95891, SMR003435989, ST024762, Theophylline, anhydrous, >=99%, powder, component of Primatene tablets (Salt/Mix), Purine,6(1H,3H)-dione, 1,3-dimethyl-, SBI-0050003.P004, AB1009249, component of Mudrane GG elixir (Salt/Mix), DB-053224, 1H-Purine-2, 3,7-dihydro-1,3-dimethyl-, AB00052106, FT-0631259, N1442, 1,3-dimethyl-1H-purine-2,6(3H,9H)-dione, 6461-EP1441224A2, 6461-EP2272835A1, 6461-EP2272841A1, 6461-EP2272844A1, 6461-EP2280006A1, 6461-EP2281813A1, 6461-EP2281815A1, 6461-EP2286811A1, 6461-EP2295434A2, 6461-EP2298305A1, 6461-EP2301933A1, 6461-EP2301936A1, 6461-EP2301937A1, 6461-EP2305219A1, 6461-EP2305640A2, 6461-EP2308562A2, 6461-EP2311827A1, 6461-EP2314590A1, C07130, D00371, 83377-EP2371823A1, AB00052106-20, AB00052106-22, AB00052106-23, AB00052106_24, AB00052106_25, AB00052106_26, 3,7-dihydro-1,3-dimethyl-1H- purine-2,6-dione, L000595, 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione #, Q-201819, SR-01000075195-1, SR-01000075195-3, SR-01000075195-5, 1,3-Dimethyl-6-hydroxy-1,3-dihydro-2H-purin-2-one, BRD-K97799481-001-02-0, BRD-K97799481-001-12-9, BRD-K97799481-002-03-6, I14-16783, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, mo, F2173-0145, Z271004650, A3133D49-AAB6-49A1-B60B-B5198F327D3F, Theophylline, British Pharmacopoeia (BP) Reference Standard, Theophylline, European Pharmacopoeia (EP) Reference Standard, (8alpha, 9S)-10,11-Dihydro-6'-methoxycinchonan-9-amine trihydrochloride, min. 90%, Theophylline melting point standard, United States Pharmacopeia (USP) Reference Standard, Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material, 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine; 1,3-Dimethylxanthine; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, 46157-00-0, 56645-32-0, InChI=1/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9, Theophylline melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material, Theophylline, certified reference material, United States Pharmacopeia (USP) Reference Standard

ID: 2805

chemical graph of compound 2805



InChIKey: ZGFJRZYSVJDCRU-UHFFFAOYSA-M
SMILES: COC1=C[N+](=CC=C1)C(CO)C2=CC=CC=C2.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 10611756

ID: 2806

chemical graph of compound 2806



InChIKey: ZGHHIOBQEXZBAG-UHFFFAOYSA-N
SMILES: C1CC2=CC(=C(C=C2CC1N)O)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11230706
synonyms found at PubChem are:
6,7-ADTN.HBr, CTK8F7016, 6,7-ADTN hydrobromide, (+/-)-Adtn hydrobromide, 13575-86-5, (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, 73304-33-3, NSC-287353, 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene HBr, MLS002172466, SMR001254097, Adtn hydrobromide, (+/-)-, SR-01000075362, EU-0100415, 2-Amino-6,7-dihydroxytetralin hydrobromide, (+/-)-, SCHEMBL3763048, CHEMBL1255656, MolPort-003-940-881, 6-amino-5,6,7,8-tetrahydro-2,3-naphthalenediol hydrobromide, Tox21_500415, NSC287353, 2,3-Naphthalenediol, 6-amino-5,6,7,8-tetrahydro-, hydrobromide (1:1), AKOS027383301, CCG-221719, LP00415, NCGC00093839-01, NCGC00261100-01, CC-00135, DB-017865, D-002, FT-0641453, FT-0708038, Aminotetraline hydrobromide, 6,7-Dihydroxy-2-, C-16205, J-006771, SR-01000075362-1, ( )-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, 2,3-Naphthalenediol,6-amino-5,6,7,8-tetrahydro-,hydrobromide(1:1), 6-AMINO-5,6,7,8-TETRAHYDRONAPHTHALENE-2,3-DIOL HYDROBROMIDE, ( inverted exclamation markA)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, ( inverted question mark)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydro-naphthalene hydrobromide

ID: 2807

chemical graph of compound 2807



InChIKey: ZGTBTVGPDLJINX-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C2=CC=CC=C2C=C1)OC(=O)C3=CC=NC=C3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 323483
synonyms found at PubChem are:
MLS003115552, NSC283844, AC1L88Q0, CHEMBL2132251, ZINC240790, NSC-283844, SMR001831126, (2-acetylnaphthalen-1-yl) pyridine-4-carboxylate

ID: 2808

chemical graph of compound 2808



InChIKey: ZGZXKIHFNHZFBL-UHFFFAOYSA-N
SMILES: CCCC1(NC(=S)N(N1)C2=NC3=CC=CC=C3S2)CCC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "N Pedemonte" "GL Lukacs" "LJ Galietta" "O Zegarra-Moran" "AS Verkman" "K Du"


CID is 885368
synonyms found at PubChem are:
2-(1,3-benzothiazol-2-yl)-5,5-dipropyl-1,2,4-triazolidine-3-thione, AC1LHCX4, Oprea1_717603, SCHEMBL838385, MolPort-001-679-743, ZINC457579, STK016145, AKOS024348547, MCULE-9221241446

ID: 2809

chemical graph of compound 2809



InChIKey: ZHPWRQIPPNZNML-UHFFFAOYSA-N
SMILES: C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 47471
synonyms found at PubChem are:
BUTOCONAZOLE NITRATE, 64872-77-1, Gynomyk, Exelgyn, Femstat One, Gynazole-1, Mycelex-3, Butoconazole (nitrate), Femstat 3, RS-35887, Butaconazole nitrate, nitrato de butoconazol, (+-)-1-(4-(4-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole mononitrate, (+-)-1-(4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)imidazole mononitrate, C19H17Cl3N2S.HNO3, CHEBI:3241, RS-35887-00-10-3, 1-(4-(4-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole nitrate, 1-(4-(4-Chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl)imidazole nitrate, 1H-Imidazole, 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-, mononitrate, DSSTox_CID_25452, DSSTox_RID_80888, DSSTox_GSID_45452, MLS002153798, 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole nitrate, 1-{4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl}-1H-imidazole nitrate, 1H-Imidazole, 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-, (+-)-, mononitrate, 1H-Imidazole, 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-, mononitrate, (+-)-, 67085-14-7, CAS-64872-77-1, SMR001233176, Butoconazole nitrate [USAN], 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole;nitric acid, 1-{4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl}-1H-imidazole nitrate, Butoconazole nitrate [USAN:USP], Femstat (TN), Butoconazole nitrate/, Gynazole-1 (TN), duplicate RN for nitrate, butoconazole; nitric acid, NCGC00016812-01, AC1L2I4O, Butoconazole nitrate (USP), SCHEMBL41394, C19H18Cl3N3O3S, CHEMBL1200398, DTXSID6045452, CTK8E8274, MolPort-003-845-449, ZHPWRQIPPNZNML-UHFFFAOYSA-N, HMS1569A18, HMS2096A18, HMS2234A19, HMS3370O18, HMS3655A16, HMS3713A18, 67085-13-6 (Parent), ACT06285, BCP02595, HY-B0293, KS-00000M1R, Tox21_110624, ABP000787, AC-199, KM0882, s1833, AKOS015855542, AKOS015964937, Tox21_110624_1, API0000434, Butoconazole nitrate, >=90% (HPLC), CCG-220408, CS-2307, NCGC00179596-03, AK164492, AN-16063, AS-14137, BC220322, K050, LS-78314, LS-78315, AB0007996, AB2000320, KB-217326, TC-070891, B4801, FT-0653569, C08066, D00880, C-46110, SR-01000841222, I14-0940, SR-01000841222-2, 1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]imidazole Nitrate, Butoconazole nitrate, United States Pharmacopeia (USP) Reference Standard, 1-(4-(4-chlorophenyl)-2-(2,6-dichlorophenylthio)butyl)-1H-imidazole nitrate, 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole; nitric acid, 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole nitrate, 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole; nitric acid, Butoconazole Nitrate, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 2810

chemical graph of compound 2810



InChIKey: ZHXIMGYEMBZGOI-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C=C(O2)C3=CC=C(C=C3)F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 261391
synonyms found at PubChem are:
4'-Fluoroflavone, 2-(4-fluorophenyl)-4h-chromen-4-one, 2-(4-fluorophenyl)chromen-4-one, 2-(4-Fluoro-phenyl)-chromen-4-one, UNII-A96898YA6S, MLS000526645, 1645-21-2, A96898YA6S, NSC-93392, 2-(4-fluorophenyl)-1-benzopyran-4-one, BAS 01121721, SMR000117119, ST070967, 4hlh, 4kzl, 20D, NSC93392, 4/'-Fluoroflavone, AC1Q4OHV, Maybridge3_000480, 2-(4-fluorophenyl)chromone, Oprea1_515170, Oprea1_675538, CHEMBL53738, AC1L657G, cid_261391, SCHEMBL2426329, BDBM89825, DTXSID40293999, MolPort-000-695-727, HMS1432F18, HMS2177I14, ZINC135412, STL328122, AKOS000603630, CCG-233341, MCULE-5111558124, IDI1_011867

ID: 2811

chemical graph of compound 2811



InChIKey: ZHXRDXTYPCPBTI-UHFFFAOYSA-N
SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 145949
synonyms found at PubChem are:
Virstatin, 88909-96-0, Isodibut, 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid, 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid, 4-(N-(1,8-naphthalimide))-n-butyric acid, 4-NAPHTHALIMIDOBUTYRIC ACID, 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butyric acid, 1,3-dioxo-1H-Benz[de]isoquinoline-2(3H)-butanoic acid, 1H-Benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-dioxo-, 4-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid, ACMC-209qxu, SpecPlus_000928, Spectrum2_000449, Spectrum3_001240, CBMicro_014897, CBKinase1_000229, CBKinase1_012629, AC1L3S8Q, AC1Q75GX, AC1Q75GY, BSPBio_002720, CBDivE_001858, CBDivE_003272, MLS001207259, DivK1c_007024, SPBio_000498, CHEMBL403272, SCHEMBL3134908, SCHEMBL3852274, CTK3E8959, KBio1_001968, KBio3_002220, DTXSID10237406, MolPort-000-434-137, KS-000024ED, ZINC3884670, ANW-39184, CCG-39963, KM2782, MFCD00181400, SBB043186, STK395003, AKOS000114634, DG-0077, MCULE-6695567974, NCGC00178507-01, AJ-47161, BAS 00114818, LS-21670, SMR000504925, TC-127929, FT-0734904, ST50049126, X6840, EN300-00247, AB00053241-05, 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid, BRD-K60241851-001-02-8, BRD-K60241851-001-06-9, Z56891243, F0303-0081, 1H-Benz[de]isoquinoline-2(3H)-butanoicacid, 1,3-dioxo-, 4-{2,4-dioxo-3-azatricyclo[7.3.1.0,(1)(3)]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid, 4-{2,4-dioxo-3-azatricyclo[7.3.1.0?,??]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid, 4-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca- 1(13),5,7,9,11-pentaen-3-yl}butanoic acid, 4-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(12),5,7,9(13),10-pentaen-3-yl}butanoic acid, 4-{2,4-dioxo-3-azatricyclo[7.3.1.05,13]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid

ID: 2812

chemical graph of compound 2812



InChIKey: ZIIQCSMRQKCOCT-RXMQYKEDSA-N
SMILES: CC(=O)N[C@H](C(=O)O)C(C)(C)SN=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 157991
synonyms found at PubChem are:
S-Nitroso-N-acetylpenicillamine, N-Acetyl-3-(nitrosothio)-valine, Valine, N-acetyl-3-(nitrosothio)-, 273921-90-7, N-acetyl-3-(nitrosothio)-D-Valine, 81739-40-4, 79032-48-7, SNAP(D), 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid, AC1L4J2E, Lopac0_000856, SCHEMBL220202, CHEMBL347940, s-nitroso-l-acetyl penicillamine, CTK2I6924, MolPort-044-812-344, HMS3262L13, N-Acetyl-S-nitroso-D-penicillamine, 152971-80-7, ZINC3793144, Tox21_500856, MFCD00272624, CCG-204939, LP00856, NCGC00094182-01, NCGC00094182-02, NCGC00094182-03, NCGC00261541-01, AS-52710, B6368, EU-0100856, FT-0672932, S-Nitroso-N-acetyl-D-|A,|A-dimethylcysteine, N 3398, SR-01000076023, SR-01000076023-1, (2R)-2-acetamido-3-methyl-3-nitrososulfanylbutanoic acid

ID: 2813

chemical graph of compound 2813



InChIKey: ZIMGGGWCDYVHOY-UHFFFAOYSA-N
SMILES: C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4201
synonyms found at PubChem are:
minoxidil, 38304-91-5, Rogaine, Loniten, Regaine, Minoximen, Theroxidil, Tricoxidil, Alopexil, Alostil, Lonolox, Minoxidilum, Normoxidil, Prexidil, Minodyl, Minossidile [Italian], 2,6-Diamino-4-(piperidin-1-yl)pyrimidine 1-oxide, Minoxidilum [INN-Latin], Minossidile, Pierminox, Apo-Gain, RiUP, Minoxigaine, Trocoxidil, Neoxidil, Gen-Minoxidil, Rogaine for Men, 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide, ROGAINE (FOR MEN), 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide, Avacor and Mintop, Rogaine for Women, MINOXIDIL (FOR MEN), ROGAINE (FOR WOMEN), Loniten (TN), Minoxidil [USAN:BAN:INN], Rogaine (TN), MINOXIDIL (FOR WOMEN), Men s Rogaine Foam, U-10858, 6-(piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide, Riup (TN), 2,4-Diamino-6-piperidinopyrimidine 3-oxide, 6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine, U 10858, ROGAINE EXTRA STRENGTH (FOR MEN), 2,6-Diamino-4-piperidinopyrimidin-1-oxid, MINOXIDIL EXTRA STRENGTH (FOR MEN), MLS000028566, C9H15N5O, CHEBI:6942, Rogaine Extra Strength for Men, 6-Piperidino-2,4-diaminopyrimidine 3-oxide, 2,4-Diamino-6-piperidinopyrimidine 3-N-oxide, 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide, 6-[1-Piperidinyl]pyrimidine-2,4-diamine 3 oxide, U-10,858, 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine, MFCD00063409, TM-160, 2,4-Diamino-6-piperidinilpirimidina-3-ossido [Italian], 2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate, MINOXIDIL EXTRA STRENGTH FOR MEN, NCGC00015673-08, SMR000058963, 2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine, CAS-38304-91-5, M1389, 2,4-Diamino-6-piperidino-pyrimidine-3-oxide, M 4145, DSSTox_CID_20685, DSSTox_RID_79541, DSSTox_GSID_40685, Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide, 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine, 6-amino-2-imino-4-(piperidin-1-yl)pyrimidin-1(2H)-ol, Men's Rogaine, 2,6-diamino-4-piperidylpyrimidin-1-ol, SMR000326812, SR-01000075331, SR-05000001479, 3-oxido-6-piperidin-1-ylpyrimidin-3-ium-2,4-diamine, Kopdil, HSDB 6538, Mens Rogaine Foam, Minoxidil,(S), UNII-5965120SH1, Prestwick_521, EINECS 253-874-2, Regaine (TN), BRN 0886240, Minoxidil Pfizer Brand, pyrimidin-1(2H)-ol, Spectrum_000969, Tocris-0583, Minoxidil (USP/INN), PfizerBrand of Minoxidil, regid855572, Opera_ID_1150, Prestwick0_000020, Prestwick1_000020, Prestwick2_000020, Prestwick3_000020, Spectrum2_001053, Spectrum3_000509, Spectrum4_000063, Spectrum5_001299, Lopac-M-4145, 2,4-Diamino-6-piperidinilpirimidina-3-ossido, CHEMBL802, D0Y2CJ, AC1L1HN1, Minoxidil (JAN/USP/INN), CBiol_001798, Lopac0_000786, SCHEMBL29698, BSPBio_000059, BSPBio_001385, BSPBio_002037, KBioGR_000105, KBioGR_000585, KBioSS_000105, KBioSS_001449, MLS000859953, MLS001077294, DivK1c_000160, SCHEMBL232565, SPECTRUM1500415, SPBio_001006, SPBio_001980, BPBio1_000065, GTPL4254, Minoxidil, >=99% (TLC), SGCUT00112, ZINC1735, Jsp006715, CHEMBL1372483, DTXSID9040685, BCBcMAP01_000193, BDBM81463, C9H15N5.H2O, CHEBI:92128, HMS500H22, KBio1_000160, KBio2_000105, KBio2_001449, KBio2_002673, KBio2_004017, KBio2_005241, KBio2_006585, KBio3_000209, KBio3_000210, KBio3_001537, BIM0127, MolPort-003-666-236, MolPort-005-932-694, NINDS_000160, ZFMITUMMTDLWHR-UHFFFAOYSA-N, ZIMGGGWCDYVHOY-UHFFFAOYSA-N, BCPP000162, Bio1_000084, Bio1_000573, Bio1_001062, Bio2_000105, Bio2_000585, HMS1361F07, HMS1568C21, HMS1791F07, HMS1920P03, HMS1989F07, HMS2089L08, HMS2091F20, HMS2095C21, HMS2233E04, HMS2235N21, HMS3259P21, HMS3262M14, HMS3266O06, HMS3371E15, HMS3372M19, HMS3402F07, HMS3712C21, Pharmakon1600-01500415, ACT04612, BCP01409, CAS_4201, HY-B0112, KS-00000X2A, NSC_4201, to_000070, ZINC6507066, Tox21_110193, Tox21_500786, 3853AH, CCG-40112, GP5950, NSC757106, s1383, SBB056986, STL453211, AKOS015920078, AKOS016339636, Tox21_110193_1, 6-amino-2-imino-4-(piperidin-1-yl), AC-5271, API0003399, BCP9000929, CCG-220020, CS-1867, DB00350, GS-3605, KS-5164, LP00786, NC00686, NSC-757106, IDI1_000160, IDI1_033855, SMP1_000192, NCGC00015673-01, NCGC00015673-02, NCGC00015673-03, NCGC00015673-04, NCGC00015673-05, NCGC00015673-06, NCGC00015673-07, NCGC00015673-09, NCGC00015673-10, NCGC00015673-11, NCGC00015673-13, NCGC00018278-01, NCGC00018278-02, NCGC00018278-03, NCGC00018278-04, NCGC00024666-01, NCGC00024666-02, NCGC00024666-03, NCGC00024666-04, NCGC00024666-05, NCGC00024666-06, NCGC00024666-07, NCGC00024666-08, NCGC00179672-01, NCGC00261471-01, AN-11161, BC201579, BR-49175, CPD000058963, H766, KB-55048, SAM002589949, SC-16492, ZB000401, SBI-0050764.P004, AB0013244, AB0093459, AB1009393, LS-135040, 2,6-Diamino-4-piperidinopyrimidine 1-Oxide, 5965120SH1, AB00513797, EU-0100786, FT-0620793, ST24027359, ST50993884, D00418, J10235, M-7481, Rogaine, Regaine, Avacor and Mintop, Minoxidil, 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide, AB00052047-08, AB00052047_09, AB00052047_10, AB00513797-02, 102666-EP2272841A1, 102666-EP2281816A1, 102666-EP2301936A1, 304M915, 6-(1-piperidinyl)-2,4-pyrimidinediamine-3-oxide, A824098, 2,4-diamino-6-(1-piperidinyl)-pyrimidine-3-oxide, Q-201408, SR-01000075331-1, SR-01000075331-3, SR-01000075331-5, SR-05000001479-1, SR-05000001479-2, 3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine, BRD-K06902185-001-05-2, BRD-K06902185-001-10-2, BRD-K14888893-001-02-3, Z1541638524, Minoxidil, European Pharmacopoeia (EP) Reference Standard, 2-azanylidene-3-oxidanyl-6-piperidin-1-yl-pyrimidin-4-amine, 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidino-pyrimidine, Minoxidil, United States Pharmacopeia (USP) Reference Standard, Minoxidil for system suitability, European Pharmacopoeia (EP) Reference Standard, 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide; 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide

ID: 2814

chemical graph of compound 2814



InChIKey: ZJBMQVPEJHVSQA-OCYVVMCSSA-N
SMILES: CC[C@]1(C[C@@H](C2=C([C@H]1C(=O)OC)C=C3C(=C2O)C(=O)C4=C(C=CC(=C4C3=O)O)O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 196990
synonyms found at PubChem are:
Pyrromycin, Pyromycin, Antibiotic MA 144T2, CCRIS 2264, MA144 T2, NSC 267229, 668-17-7, (1R-(1alpha,2beta,4beta))-2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-1-naphthacenecarboxylic acid, methyl ester, 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R,2R,4S)-, 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-, methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate, Pyyromycin, Pyrromycin (8CI), Spectrum_001680, Spectrum2_000694, Spectrum3_000229, Spectrum4_000945, Spectrum5_000895, AC1L52ON, BSPBio_001877, KBioGR_001530, KBioSS_002160, SPECTRUM201604, SPBio_000847, CHEMBL3039044, KBio2_002160, KBio2_004728, KBio2_007296, KBio3_001377, HMS1923A19, CCG-39695, AKOS027426996, NCGC00178933-01, LS-93908, SR-05000002759, SR-05000002759-1, 1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2

ID: 2815

chemical graph of compound 2815



InChIKey: ZJJXGWJIGJFDTL-UHFFFAOYSA-N
SMILES: CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3478
synonyms found at PubChem are:
glipizide, 29094-61-9, Glucotrol, Glydiazinamide, Melizide, Glibenese, Glucozide, Glupizide, Sucrazide, Dipazide, Glupitel, Mindiab, Minidiab, Minodiab, Napizide, Ozidia, Glucotrol XL, Glibetin, Glucolip, Aldiab, Digrin, Glican, Glidiab, Glipid, Minidab, Glyde, Gluco-Rite, Glipizidum, Glipizida, Glide, Glidiazinamide, Glypidizine, Metaglip, Glipizidum [INN-Latin], Glipizida [INN-Spanish], K 4024, K-4024, CP 28720, Semiglynase, TK 1320, C21H27N5O4S, CP-28720, CP 28,720, UNII-X7WDT95N5C, Glucotrol (TN), Glipizide [USAN:BAN:INN], Glipizide (Glucotrol), Glipizide (USP/INN), EINECS 249-427-6, BRN 0903495, CHEMBL1073, X7WDT95N5C, 1-Cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)urea, MLS000069386, N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide, CHEBI:5384, K4024, Glipizide Extended-Release Tablets, N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-5-methylpyrazine-2-carboxamide, N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide, N-(4-(beta-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N'-cyclohexylurea, Pyrazinecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-, KS-1068, NCGC00015462-07, SMR000058455, CP-28,720, CAS-29094-61-9, G-117, 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea, DSSTox_CID_20676, DSSTox_RID_79535, Urea, 1-cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)-, DSSTox_GSID_40676, W-107005, 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea, 1-Cyclohexyl-3-{4-[2-(5-methylpyrazine-2-carboxamido)ethyl]phenylsulfonyl}urea, N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-pyrazine-2-carboxamide, N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide, N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea, 29094-66-4, Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-, SR-01000000010, glipizid, Glipizibe, Glipizide, solid, N-(4-[N-(cyclohexylcarbamoyl)sulfamoyl]phenethyl)-5-methylpyrazine-2-carboxamide, Glipizide [USAN:USP:INN:BAN], Glipizide,(S), Prestwick_242, Metaglip (Salt/Mix), Glipizide Kenfarma Brand, Lopac-G-117, Lacer Brand of Glipizide, Lilly Brand of Glipizide, Opera_ID_1908, Prestwick0_000131, Prestwick1_000131, Prestwick2_000131, Prestwick3_000131, D0Z4SB, Samarium(III) ionophore I, AC1L1G0Z, AC1Q2OG0, Kenfarma Brand of Glipizide, PfizerBrand 1 of Glipizide, Glibenese Brand of Glipizide, CBiol_001788, Lopac0_000621, SCHEMBL17094, BSPBio_000202, BSPBio_001349, KBioGR_000069, KBioSS_000069, Pfizer Brand 2 of Glipizide, Alphapharm Brand of Glipizide, MLS001148176, BIDD:GT0476, SPBio_002141, BPBio1_000224, GTPL6821, DTXSID0040676, CTK8B3212, KBio2_000069, KBio2_002637, KBio2_005205, KBio3_000137, KBio3_000138, MolPort-002-885-830, ZJJXGWJIGJFDTL-UHFFFAOYSA-N, Bio1_000074, Bio1_000563, Bio1_001052, Bio2_000069, Bio2_000549, HMS1361D11, HMS1568K04, HMS1791D11, HMS1989D11, HMS2089C21, HMS2093J09, HMS2095K04, HMS2233N11, HMS3259K12, HMS3261N04, HMS3369L12, HMS3402D11, HMS3655G04, HMS3712K04, Pharmakon1600-01505433, ZINC537795, BCP09195, Glucotrol XL, Glucotrol, Glipizide, HY-B0254, Tox21_110156, Tox21_301834, Tox21_500621, ANW-41980, BBL028143, BDBM50012956, BG0209, MFCD00072159, NSC759120, s1715, STK631952, AKOS005564405, Tox21_110156_1, API0002842, CCG-204710, CS-2239, DB01067, LP00621, MCULE-5142805548, NC00564, NSC-759120, IDI1_033819, NCGC00015462-01, NCGC00015462-02, NCGC00015462-03, NCGC00015462-04, NCGC00015462-05, NCGC00015462-06, NCGC00015462-08, NCGC00015462-09, NCGC00015462-10, NCGC00015462-11, NCGC00015462-12, NCGC00015462-14, NCGC00016802-01, NCGC00023748-03, NCGC00023748-04, NCGC00023748-05, NCGC00023748-06, NCGC00023748-07, NCGC00255522-01, NCGC00261306-01, AC-15789, AN-15826, BC209538, CC-28982, CPD000058455, KB-52251, SAM002564210, SC-13933, SBI-0050603.P002, AB0012143, LS-159679, TC-063559, TL8006447, EU-0100621, FT-0626714, FT-0659737, G0369, ST50826363, D00335, 094G619, C-22417, I06-0186, I06-1985, SR-01000000010-2, SR-01000000010-5, BRD-K12219985-001-04-8, BRD-K12219985-001-15-4, Z1880962274, Glipizide, European Pharmacopoeia (EP) Reference Standard, Glipizide, United States Pharmacopeia (USP) Reference Standard, Glipizide, Pharmaceutical Secondary Standard; Certified Reference Material, N-[4-(3-Cyclohexylureidosulfonyl)phenethyl]-5-methyl-2-pyrazinecarboxamide, 1-cyclohexyl-3-(4-(2-(2-methylpyrazine-5-carboxamido)ethyl)phenylsulfonyl)urea, N-(4-(.beta.-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N'-cyclohexylurea, 172964-66-8, 38777-27-4, N-(2-[4-(([(Cyclohexylamino)carbonyl]amino)sulfonyl)phenyl]ethyl)-5-methyl-2-pyrazinecarboxamide, N-[2-(4-{[(cyclohexylamino)carbonylamino]sulfonyl}phenyl)ethyl](5-methylpyrazi n-2-yl)carboxamide

ID: 2816

chemical graph of compound 2816



InChIKey: ZJKNESGOIKRXQY-UHFFFAOYSA-N
SMILES: CC1=C(NC(=O)N1)C(=O)C2=CC=C(C=C2)SC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 53708
synonyms found at PubChem are:
ENOXIMONE, Perfan, 77671-31-9, Fenoximone, Enoximonum [Latin], Enoximona [Spanish], MDL-17043, Enoximona, Enoximonum, MDL 17,043, Perfane, UNII-C7Z4ITI7L7, Enoximone [USAN:BAN:INN], MDL-17,043, Perfan (TN), Enoximone (USAN/INN), RMI-17043, 4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one, C7Z4ITI7L7, 4-Methyl-5-(p-(methylthio)benzoyl)-4-imidazolin-2-one, CHEMBL249856, 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-, NCGC00015400-02, 1,3-Dihydro-4-methyl-5-[4-methylthiobenzoyl]-2H-imidazol-2-one, E 1279, DSSTox_CID_25147, DSSTox_RID_80702, DSSTox_GSID_45147, 1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one, SMR000857318, CAS-77671-31-9, Enoximone [USAN:INN:BAN], 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-, Enoximone, solid, AC1L1FGC, Lopac-E-1279, D08EYI, D0E0SW, AC1Q4GY8, Lopac0_000410, SCHEMBL44049, MLS001335963, MLS001335964, MLS002172494, GTPL9063, SCHEMBL5702510, DTXSID8045147, CTK8E9085, CHEBI:135010, HMS2234C20, HMS3261A22, HMS3369O01, BCP04265, ZINC9225358, Tox21_110137, Tox21_500410, 1,3-Dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one, BDBM50241379, MFCD00867130, AKOS005145769, Tox21_110137_1, AC-3396, API0002549, CCG-204503, DB04880, LP00410, NCGC00015400-01, NCGC00015400-03, NCGC00015400-04, NCGC00015400-05, NCGC00093835-01, NCGC00093835-02, NCGC00261095-01, AN-13012, CC-27472, K360, LS-78854, SC-47916, B6833, EU-0100410, FT-0630855, D04004, 671E319, C-15217, SR-01000075850, SR-01000075850-1, 4-methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one, 5-methyl-4-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one, 4-methyl-5-(4-(methylthio)benzoyl)-1,3-dihydro-2H-imidazol-2-one, 4-Methyl-5-(4-methylsulfanyl-benzoyl)-1,3-dihydro-imidazol-2-one, 4-methyl-5-[4-(methylsulfanyl)benzoyl]-1,3-dihydroimidazol-2-one, 2H-Imidazol-2-one,1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-, 4-methyl-5-[4-(methylsulfanyl)benzoyl]-1,3-dihydro-2H-imidazol-2-one, (enoximone)4-Methyl-5-(4-methylsulfanyl-benzoyl)-1,3-dihydro-imidazol-2-one, 4-Methyl-5-(4-methylsulfanyl-benzoyl)-1,3-dihydro-imidazol-2-one (Enoximone), 4-Methyl-5-(4-methylsulfanyl-benzoyl)-1,3-dihydro-imidazol-2-one(Enoximone), 4-Methyl-5-(4-methylsulfanyl-benzoyl)-1,3-dihydro-imidazol-2-one(fenoximone, MDL-17043), 4-methyl-5-{[4-(methylsulfanyl)phenyl]carbonyl}-2,3-dihydro-1H-imidazol-2-one

ID: 2817

chemical graph of compound 2817



InChIKey: ZJONSYFOVDKINV-UHFFFAOYSA-N
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=C(C(=C(C=C4)O)O)O

biological descriptors:

CFTR relevance: proteostasis regulator (targeting disabled autophagy and CK2 overactivation)

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"S Esposito" "CA Leone" "S Guido" "A Sepe" "A Tosco" "E Ferrari" "D De Stefano" "A Di Pasqua" "G Stoll" "I Sana" "L Maiuri" "F De Gregorio" "G De Rosa" "V Raia" "R Grassia" "P Buonpensiero" "L Salvadori" "S Lusa" "G Kroemer" "G Bona" "A Mehta" "MC Maiuri"


CID is 44134699
synonyms found at PubChem are:
(-) EPIGALLOCATECHIN GALLATE, BDBM84980, AC-390, AKOS015963174, BC215524, A845931, [5,7-bis(oxidanyl)-2-[3,4,5-tris(oxidanyl)phenyl]-3,4-dihydro-2H-chromen-3-yl] 2,3,4-tris(oxidanyl)benzoate, 2,3,4-trihydroxybenzoic acid [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl] ester, 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 2,3,4-trihydroxybenzoate

ID: 2818

chemical graph of compound 2818



InChIKey: ZJRFCXHKYQVNFK-HPUCVXDUSA-M
SMILES: C1C2[C@@H](C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957455
synonyms found at PubChem are:
8-Bromo-cGMP sodium, HMS3260I22, Tox21_500130, CCG-221434, LP00130, NCGC00260815-01, EU-0100130, 8-Bromoguanosine-3',5'-cyclophosphate sodium, B 1381

ID: 2819

chemical graph of compound 2819



InChIKey: ZJVFLBOZORBYFE-UHFFFAOYSA-N
SMILES: CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3671
synonyms found at PubChem are:
ibudilast, 50847-11-5, Ketas, Ibudilastum, KC-404, Ke Tas, Ibudilastum [Latin], Ibudilast [INN:JAN], MN-166, Eyevinal, AV-411, UNII-M0TTH61XC5, Ketas (TN), 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, 3-Isobutyryl-2-isopropylpyrazolo(1,5-a)pyridine, Tocris-1694, Ibudilast (JAN/INN), Lopac-I-0157, 2-Isopropyl-3-isobutyrylpyrazolo(1,5-a)pyridine, 1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one, AV 411, KC 404, 2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one, BRN 0656579, M0TTH61XC5, CHEMBL19449, I0157_SIGMA, 1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-, Pyrazolo(1,5-a)pyridine, 3-isobutyryl-2-isopropyl-, NCGC00015542-05, 1-(2-Isopropylpyrazolo(1,5-a)pyridin-3-yl)-2-methyl-1-propanone, 1-Propanone, 2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-, I 0157, DSSTox_CID_28933, DSSTox_RID_83199, 2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine, DSSTox_GSID_49007, 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone, 2-Methyl-1-[2-(Propan-2-Yl)pyrazolo[1,5-A]pyridin-3-Yl]propan-1-One, CAS-50847-11-5, SR-01000075927, Pinatos, AV411, Ibudilast,(S), AC1L1GGB, Ibudilast (JP17/INN), D03QJL, Lopac0_000599, SCHEMBL30390, 5-24-03-00396 (Beilstein Handbook Reference), MLS000862198, GTPL7399, ZINC4234, DTXSID7049007, CHEBI:31684, CTK8B3008, KS-00000LWH, MolPort-003-848-127, ZJVFLBOZORBYFE-UHFFFAOYSA-N, BCPP000209, HMS2089B21, HMS2233H08, HMS3261H20, HMS3268O11, HMS3374P02, HMS3715L09, BCP02335, HY-B0763, Tox21_113503, Tox21_500599, ANW-41585, BDBM50240404, BS0097, KP-305, MFCD00864808, SBB056343, Ibudilast, >=99% (HPLC), solid, AKOS015895123, Tox21_113503_1, AC-1044, API0002963, BCP9000768, CCG-204688, CS-2966, DB05266, LP00599, RL03870, NCGC00015542-01, NCGC00015542-02, NCGC00015542-03, NCGC00015542-04, NCGC00015542-06, NCGC00015542-07, NCGC00025261-01, NCGC00025261-02, NCGC00025261-03, NCGC00025261-04, NCGC00261284-01, AJ-08199, AK160499, AN-15342, BC205064, SMR000326961, AB0007937, AX8005265, KB-308542, LS-129153, TR-018156, EU-0100599, FT-0654591, I0740, ST24047395, D01385, AB00698306-06, 3-Isobutyryl-2-isopropyl-Pyrazolo(1,5-a)pyridine, 847I115, A828320, H-20256, L003042, I06-0361, J-512714, SR-01000075927-1, SR-01000075927-3, SR-01000075927-6, BRD-K16444452-001-03-4, 1-(2-isopropylH-pyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one, 1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methyl-propan-1-one, 1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3-yl)-2-methyl-propan-1-one, 1-(2-Isopropyl-pyrazolo[1,5-alpha]pyridin-3-yl)-2-methyl-propan-1-one, 1-(2-isopropylpyrazolo[1,5-alpha]pyridin-3-yl)-2-methylpropan-1-one, 2-methyl-1-(2-propan-2-yl-3-pyrazolo[1,5-a]pyridinyl)-1-propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone, (Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3-yl)-2-methyl-propan-1-one, 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one (Ibudilast), 2-methyl-1-[2-(methylethyl)(8-hydropyrazolo[1,5-a]pyridin-3-yl)]propan-1-one, AVL

ID: 2820

chemical graph of compound 2820



InChIKey: ZJXVNNSMRGTDBI-UHFFFAOYSA-N
SMILES: C1=C(C=C2C(=C1O)C(=O)C3=C(C=C(C=C3C2=O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 361510
synonyms found at PubChem are:
Emodic acid, MLS000876948, NSC624610, SMR000440655, 4,5,7-Trihydroxy-9,10-dioxo-9,10-dihydro-2-anthracenecarboxylic acid, 478-45-5, 4,5,7-trihydroxy-9,10-dioxoanthracene-2-carboxylic acid, Spectrum_000189, SpecPlus_000784, AC1Q5TTZ, Spectrum2_000421, Spectrum3_001129, Spectrum4_001974, Spectrum5_000645, AC1L7IT6, BSPBio_002597, KBioGR_002473, KBioSS_000669, DivK1c_006880, SPECTRUM1504060, SPBio_000402, CHEMBL290914, cid_361510, MEGxm0_000113, SCHEMBL5073407, ACon0_001437, ACon1_000410, CHEBI:93655, CTK1D6935, KBio1_001824, KBio2_000669, KBio2_003237, KBio2_005805, KBio3_002097, MolPort-001-739-339, ZJXVNNSMRGTDBI-UHFFFAOYSA-N, BDBM115127, HMS2267O14, ZINC3977762, CCG-38681, MCULE-5764934360, NSC-624610, SDCCGMLS-0066762.P001, NCGC00095847-01, NCGC00095847-02, NCGC00095847-03, 4,5,7- trihydroxy-2-carboxyanthraquinone, 4,5,7-trihydroxyanthraquinone-2-carboxylic acid, BRD-K94841585-001-03-6, 4,5,7-trihydroxy-9,10-diketo-anthracene-2-carboxylic acid, 4,5,7-trihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, 4,5,7-trihydroxy-9,10-dioxo-anthracene-2-carboxylic acid, 2-Anthracenecarboxylicacid, 9,10-dihydro-4,5,7-trihydroxy-9,10-dioxo-, 4,5,7-tris(oxidanyl)-9,10-bis(oxidanylidene)anthracene-2-carboxylic acid

ID: 2821

chemical graph of compound 2821



InChIKey: ZKKYQWOBXVJKIR-UHFFFAOYSA-N
SMILES: C1CC2=CC=CC=C2C3(C1)CCN(CC3)CC4=CC=CC=C4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957591
synonyms found at PubChem are:
L-687,384 hydrochloride, CHEMBL1256916, NCGC00094067-01, 1'-Benzyl-3,4-dihydrospiro[naphthalene-1-(2H),4'-piperidine] hydrochloride, EU-0100719, MLS002153397, CTK8G0464, Tox21_500719, CCG-222023, LP00719, NCGC00261404-01, SMR001230776, L 8539, SR-01000075964, SR-01000075964-1, L-687,384 hydrochloride, >=98% (HPLC), powder, 1 inverted exclamation marka-Benzyl-3,4-dihydrospiro-[naphthalene-1-(2H),4 inverted exclamation marka-piperidine]

ID: 2822

chemical graph of compound 2822



InChIKey: ZLHFONARZHCSET-UHFFFAOYSA-N
SMILES: C(CC(=O)O)C(=O)CN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 123608
synonyms found at PubChem are:
5-Aminolevulinic acid hydrochloride, 5451-09-2, 5-Amino-4-oxopentanoic acid hydrochloride, Levulan, Aminolevulinic acid hydrochloride, Levulan Kerastick, delta-Aminolevulinic acid hydrochloride, Gliolan, Aminolevulinic Acid HCl, Ameluz, 5-Aminolevulinate hydrochloride, 5-amino-levulinic acid hydrochloride, UNII-V35KBM8JGR, Pentanoic acid, 5-amino-4-oxo-, hydrochloride, V35KBM8JGR, 5-Aminolevulinic acid (hydrochloride), 5-Aminolevulinic acid HCl, 5-Aminolaevulinic acid hydrochloride, EINECS 226-679-5, NSC 18509, NCGC00095111-01, 5-Amino-3-oxopentanoic acid (hydrochloride), Levulan (TN), C5H9NO3.HCl, A-6100, A-6102, A-6103, DSSTox_CID_25914, DSSTox_RID_81222, DSSTox_GSID_45914, 5-amino-4-oxopentanoic acid hydrochloride;5-Amino-4-oxopentanoic acid, 5-amino-4-oxopentanoic acid, chloride, CAS-5451-09-2, 4-carboxy-2-oxobutan-1-aminium chloride, 5-Aminolevulinic acid hydrochloride, >=97.0% (AT), Gleolan, AlaCare, Ameluz (TN), ALA HCl, ALA-PDT, AC1L3WYV, AC1Q5HEA, 5-aminolevulinic acid.HCl, 5 ALA HCL, D0O4GY, 5-Aminolevulinic acid, HCl, Pentanoic acid, hydrochloride, 5-amino-4-keto-valeric acid, KSC269S3H, SCHEMBL192308, SPECTRUM1504184, TPC-I025, CHEMBL1200582, DTXSID5045914, CTK1G9933, CHEBI:132969, MolPort-001-757-321, ZLHFONARZHCSET-UHFFFAOYSA-N, HMS1922F13, PD-P-506-A, Pharmakon1600-01504184, ACT05562, BCP02161, HY-N0305, KS-000001DZ, NSC18509, ZX-AT009947, 5-amino levulinic acid hydrochloride, Tox21_111426, ANW-43114, CA-291, CCG-39079, GM8475, MFCD00012869, NSC-18509, NSC758687, OR1490, SBB003880, del.-Aminolevulinic acid hydrochloride, AKOS015904495, Tox21_111426_1, AC-4252, ACN-040155, AT-6127, BCP9000174, CS-2575, GS-3020, MCULE-8125179397, NSC-758687, RL04038, RP23037, RTR-019277, 5-Amino-4-oxovaleric acid hydrochloride, 5-aminolevulinic acid hydrochloride salt, .delta.-Aminolevulinic acid hydrochloride, 5-Amino-4-ketovaleric acid hydrochloride, 5-AMINO-4-OXOPENTANOIC ACID HCL, 5-Aminolevulinic acid hydrochloride, GMP, Aminolevulinic acid hydrochloride [USAN], Levulinic acid, 5-amino-, hydrochloride, NCGC00095111-02, NCGC00095111-03, NCGC00178086-03, 5-Aminolevulinic Acid, Hydrochloride Salt, AK-30504, BC210778, BR-30504, CC-21174, LS-87948, SC-18502, SC-52394, CAS 5451-09-2, AB1005459, AX8102341, DB-005367, KB-196689, KB-244625, ST2411714, TR-019277, 5-Aminolevulinic acid hydrochloride, >=98%, A0325, AM20100341, FT-0082845, S2553, ST50824911, Aminolevulinic acid hydrochloride (JAN/USAN), D02908, M-2865, Levulinic acid, 5-amino-, hydrochloride (8CI), 451A092, C-04944, I14-1649, Pentanoicacid, 5-amino-4-oxo-, hydrochloride (1:1), 0C1E43DB-1221-4963-BFA4-18D3170000A4, 5-Aminolevulinic acid hydrochloride, particle size < 0.25 mm, 5-Aminolevulinic acid hydrochloride, BioReagent, suitable for cell culture, powder, >=98%, Aminolevulinic acid hydrochloride, United States Pharmacopeia (USP) Reference Standard, delta-AMINOLEVULINIC ACID HCl, AKOS026750168, FT-0601317

ID: 2823

chemical graph of compound 2823



InChIKey: ZLUNDKGGMHFJPK-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1C2=CC(=O)C3=C(O2)C(=CC=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6708756
synonyms found at PubChem are:
8,2'-DIMETHOXYFLAVONE, 115713-42-3, 4H-1-Benzopyran-4-one, 8-methoxy-2-(2-methoxyphenyl)-, KBio1_001771, ACMC-20mlgr, Spectrum_000317, SpecPlus_000731, Spectrum2_000326, Spectrum3_000245, Spectrum4_001715, Spectrum5_000450, AC1O8FN2, BSPBio_001630, KBioGR_002070, KBioSS_000797, DivK1c_006827, SCHEMBL516353, SPECTRUM1500740, SPBio_000331, CHEMBL1516007, CTK0G0662, KBio2_000797, KBio2_003365, KBio2_005933, KBio3_001130, DTXSID30425106, CHEBI:107649, CCG-38602, AKOS030553546, NCGC00095956-01, NCGC00095956-02, NCGC00179137-01, 8-methoxy-2-(2-methoxyphenyl)chromen-4-one

ID: 2824

chemical graph of compound 2824



InChIKey: ZLWYEPMDOUQDBW-UHFFFAOYSA-N
SMILES: C1=CC(=NC=C1C(=O)N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9500
synonyms found at PubChem are:
6-aminonicotinamide, 329-89-5, 6-Aminopyridine-3-carboxamide, 2-Amino-5-carbamoylpyridine, 3-PYRIDINECARBOXAMIDE, 6-AMINO-, 6-amino-3-pyridinecarboxamide, 6-Aminonicotinic acid amide, 6-Aminonikotinsaeureamid, Nicotinamide, 6-amino-, Aminonicotinamide, FDA 0121, NSC 21206, 6-AN, SR 4388, 6-Amino-nicotinsaeureamid, UNII-D6FNW67F2B, U-8774, CCRIS 7679, 6-Aminonikotinsaeureamid [German], NSC21206, EINECS 206-349-7, BRN 0116042, 6-ANA, D6FNW67F2B, AI3-50770, CHEBI:74514, ZLWYEPMDOUQDBW-UHFFFAOYSA-N, 6-Aminonitoinamide, 6-amino-nicotinamide, 6-Amino nicotinamide, ACMC-1CRSU, Spectrum2_001709, Spectrum3_001976, Aminonicotinamide (Related), NCIMech_000769, WLN: T6NJ BZ EVZ, 6-Aminonicotinamide, 99%, AC1L1T6M, AC1Q4ZC9, DSSTox_CID_30043, DSSTox_GSID_51446, BSPBio_003576, 5-22-13-00618 (Beilstein Handbook Reference), MLS002207034, 2-Aminopyridine-5-carboxamide, SCHEMBL105510, SPECTRUM1505315, SPBio_001698, 6-azanylpyridine-3-carboxamide, CHEMBL1324108, DTXSID5051446, CTK3J0288, KBio3_002955, KS-00000KUJ, Nicotinamide, 6-amino- (8CI), MolPort-001-769-428, BDBM225673, GTC000445A, ALBB-025399, Tox21_303956, ANW-27511, CCG-35857, NSC-21206, SBB051875, ZINC19796190, AKOS003406190, MCULE-4611667997, RTR-013828, TRA0057959, 3-Pyridinecarboxamide, 6-amino- (9CI), NCGC00095299-01, NCGC00095299-02, NCGC00095299-03, NCGC00357190-01, AJ-75033, AN-44337, BP-13037, CAS-329-89-5, KB-44635, NCI60_001784, SC-45404, SMR001306701, ST076851, TS-00033, AB0119844, AB1003032, DB-048308, LS-130528, TR-013828, A0986, FT-0620940, R1140, ST24045111, Z2495, 329A895, A821549, I02-1579, W-202353, 4FG

ID: 2825

chemical graph of compound 2825



InChIKey: ZMISODWVFHHWNR-UHFFFAOYSA-N
SMILES: C1CNCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 15723
synonyms found at PubChem are:
Azacyclonol, 115-46-8, diphenyl(piperidin-4-yl)methanol, Frenquel, alpha,alpha-Diphenyl-4-piperidinemethanol, alpha,alpha-diphenyl-4-piperidinomethanol, alpha-(4-Piperidyl)benzhydrol, gamma-Pipradol, Ataractan, Calmeran, Diphenyl-piperidin-4-yl-methanol, 4-Piperidinemethanol, alpha,alpha-diphenyl-, Azaciclonolo [DCIT], Azacyklonol, Frenoton, MER 17, Psychosan, Diphenyl(4-piperidinyl)methanol, Azacyclonol [INN:BAN], UNII-2MMR990PEM, Azacyclonolum [INN-Latin], EINECS 204-092-5, Diphenyl-4-piperidylmethanol, BRN 0230221, 2MMR990PEM, MLS000558844, CHEMBL127508, 4-(alpha,alpha Diphenyl) piperidine methanol, ZMISODWVFHHWNR-UHFFFAOYSA-N, NCGC00016366-01, CAS-115-46-8, SMR000149160, DSSTox_CID_25280, DSSTox_RID_80781, 4-Piperidinemethanol, .alpha.,.alpha.-diphenyl-, DSSTox_GSID_45280, diphenyl-4-piperidylmethan-1-ol, Azaciclonolo, Azacyclonolum, .gamma.-Pipradol, Azacyclonol (alpha,alpha-Diphenyl-4-piperidinomethanol), Prestwick_84, PubChem23824, Maybridge3_001033, Opera_ID_1183, Prestwick0_000093, Prestwick1_000093, Prestwick2_000093, Prestwick3_000093, timtec-bb sbb003057, ACMC-2099qa, D08TBU, EC 204-092-5, AC1L26HO, Oprea1_114075, Oprea1_848733, BSPBio_000046, diphenyl 4-piperidyl carbinol, diphenyl(4-piperidyl)methanol, KSC909E9N, MLS001201777, SCHEMBL241817, SPBio_001985, BPBio1_000052, DTXSID2045280, 1798-50-1 (hydrochloride), CHEBI:93706, CTK8A9296, KS-00000NQJ, .alpha.-(4-Piperidyl)benzhydrol, alpha-(Piperidin-4-yl)benzhydrol, MolPort-001-888-124, Diphenyl(4-piperidinyl)methanol #, HMS1433O21, HMS1568C08, HMS2095C08, HMS2230G14, HMS3652K11, HMS3712C08, 4-(Diphenylhydroxymethyl)piperidine, 4-(hydroxydiphenylmethyl)piperidine, ACT07452, HY-B0530, ZX-AT014984, 4-(diphenylhydroxymethyl) piperidine, Tox21_110399, ANW-16880, BBL010986, BDBM50017724, CCG-51239, CD-021, MFCD00066980, s3196, SBB003057, STK802108, ZINC12375998, AKOS000121583, MER-17, MDL-4,829, Tox21_110399_1, 4-(hydroxy-diphenyl-methyl)-piperidine, AC-2127, CS-2754, MCULE-3573622912, OR13627, alpha,alpha-diphenyl-4-piperidinemethano, IDI1_012420, NCGC00016366-02, NCGC00016366-04, NCGC00179677-01, AJ-61958, AK-78903, AN-14251, AS-13114, BAS 04395180, BC208224, H361, SC-15689, alpha, alpha-diphenyl-4-piperidinemethanol, alpha,alpha -diphenyl-4-piperidinemethanol, AB0013009, alpha,alpha -diphenyl-4-piperidine-methanol, AX8008979, DB-041270, KB-251680, LS-115607, ST2406816, TL8000455, 4CH-018255, AM20020238, FT-0622512, P1369, ST50275420, .alpha.,.alpha.-Diphenyl-4-piperidinemethanol, Diphenyl(piperidin-4-yl)methanol (Azacyclonol), M-1450, SR-01000640550, J-003293, J-523943, SR-01000640550-1, SR-01000640550-4, BRD-K97061094-001-03-2, Diphenyl(piperidin-4-yl)methanol (Azacyclonol; Pipradrol 4-Isomer), Diphenyl(piperidin-4-yl)methanol (Azacyclonol; Pipradrol 4-Isomer) 1.0 mg/ml in Methanol

ID: 2826

chemical graph of compound 2826



InChIKey: ZMMJGEGLRURXTF-UHFFFAOYSA-N
SMILES: CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 14710
synonyms found at PubChem are:
ETHIDIUM BROMIDE, Homidium bromide, 1239-45-8, Dromilac, EtBr, 3,8-Diamino-5-ethyl-6-phenylphenanthridinium bromide, Ethydium bromide, 3,8-Diamino-5-ethyl-6-phenylphenanthridin-5-ium bromide, 2,7-Diamino-10-ethyl-9-phenylphenanthridinium bromide, 2,7-Diamino-9-phenyl-10-ethylphenanthridinium bromide, UNII-059NUO2Z1L, 2,7-Diamino-9-phenylphenanthridine ethobromide, Homidium bromide [INN:BAN], Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-, bromide, Homidii bromidum [INN-Latin], CCRIS 1017, HSDB 7297, Bromure d'homidium [INN-French], Bromuro de homidio [INN-Spanish], EINECS 214-984-6, NSC 268986, RD 1572, 3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide, AI3-62997, MLS002702536, 059NUO2Z1L, CHEBI:4883, NSC268986, NCGC00091387-01, NCGC00095070-01, DSSTox_CID_5258, E-4000, DSSTox_RID_77719, DSSTox_GSID_25258, Homidii bromidum, CHEMBL284328, Bromure d'homidium, Bromuro de homidio, CAS-1239-45-8, 2,7-Diamino-9-Phenyl-10-Ethylphenanthridiniumbromide, 5-ethyl-6-phenylphenanthridine-3,8-diamine, bromide, Ethidium bromide solution, Ethidium bromide, 98%, SCHEMBL20520, SPECTRUM1503806, AC1L24E9, AC1Q2C92, Ethidium bromide, >=95.0%, SCHEMBL1505620, DTXSID8025258, CTK3J2116, HMS502O22, MolPort-003-666-501, ZMMJGEGLRURXTF-UHFFFAOYSA-N, ZX-AFC000512, ZX-AFC003107, HMS1922I08, Pharmakon1600-01503806, Ethidium bromide, ~95% (HPLC), KS-000000YI, Tox21_111123, Tox21_111410, Tox21_202511, ANW-41701, BI4663, CCG-39365, GT1710, LS-688, MFCD00011724, NSC758630, Ethidium bromide solution, 10 mg/mL, AKOS015904050, Tox21_111410_1, AM84361, MCULE-8684380812, NSC-268986, NSC-758630, RTR-003732, Ethidium bromide, for biochemistry, 98%, NCGC00091387-08, NCGC00095070-02, NCGC00260060-01, AK114459, AN-48932, SMR001566146, AX8127683, KB-234388, TR-003732, E0370, FT-0614786, ST24041300, ST50308645, C11161, Ethidium bromide, Vetec(TM) reagent grade, 95%, SR-01000872761, SR-01000872761-1, 2,7-Diamino-10-ethyl-6-phenylphenanthridinium bromide, 5-Ethyl-6-phenyl-phenanthridine-3,8-diamine bromide, Ethidium bromide, for fluorescence, >=95.0% (HPLC), I14-17987, Phenanthridinium,8-diamino-5-ethyl-6-phenyl-, bromide, 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine bromide, Ethidium bromide solution, for fluorescence, ~1% in H2O, WLN: T B666 HKJ EJ H2 IR& LZ &E &9/26, 5-ethyl-6-phenyl-phenanthridin-5-ium-3,8-diamine bromide, Ethidium bromide, ~10 mg/tablet ethidium bromide, tablet, Ethidium bromide, BioReagent, for molecular biology, powder, J Mol Biol 13: 269 (1965); 27: 87 (1967), Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-, bromide (1:1), Ethidium bromide solution, BioReagent, for molecular biology, 10 mg/mL in H2O, Ethidium bromide solution, BioReagent, for molecular biology, 500 mug/mL in H2O, 131089-24-2, 35322-47-5, 125546-EP2272972A1, 125546-EP2272973A1, 125546-EP2277872A1, 125546-EP2279750A1, 125546-EP2289890A1, 125546-EP2295424A1, 2,7-Diamino-10-ethyl-9-phenylphenanthridinium bromide >95%

ID: 2827

chemical graph of compound 2827



InChIKey: ZMQAAUBTXCXRIC-UHFFFAOYSA-N
SMILES: C=CCC1=CC2=C(C=C1)OCO2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5144
synonyms found at PubChem are:
safrole, 94-59-7, Safrol, 5-Allyl-1,3-benzodioxole, Shikimole, Shikomol, Safrene, Sassafras, Rhyuno oil, Safrole MF, Allylcatechol methylene ether, Shikimol, 1,3-Benzodioxole, 5-(2-propenyl)-, 5-(2-Propenyl)-1,3-benzodioxole, m-Allylpyrocatechin methylene ether, Allylpyrocatechol methylene ether, 4-Allylpyrocatechol formaldehyde acetal, 3,4-(Methylenedioxy)allylbenzene, 4-Allyl-1,2-methylenedioxybenzene, Allyldioxybenzene methylene ether, RCRA waste number U203, 1,2-Methylenedioxy-4-allylbenzene, 1-Allyl-3,4-methylenedioxybenzene, Caswell No. 729, 1,3-Benzodioxole, 5-allyl-, Benzene, 4-allyl-1,2-(methylenedioxy)-, NSC 11831, CCRIS 553, UNII-RSB34337V9, Benzene, 1,2-methylenedioxy-4-allyl-, 5-allylbenzo[d][1,3]dioxole, HSDB 2653, EINECS 202-345-4, RCRA waste no. U203, EPA Pesticide Chemical Code 097901, BRN 0136380, 3-(3,4-Methylenedioxyphenyl)prop-1-ene, 1,3-Benzodioxole, 5-(2-propen-1-yl)-, AI3-00514, CHEBI:8994, 3,4-methylenedioxy-allylbenzene, 5-prop-2-enyl-1,3-benzodioxole, ZMQAAUBTXCXRIC-UHFFFAOYSA-N, RSB34337V9, (Allyldioxy)benzene methylene ether, 1-Allyl-3,4-(methylenedioxy)benzene, 4-Allyl-1,2-(methylenedioxy)benzene, (1,2-(Methylenedioxy)-4-allyl)benzene, 3-[(3,4-Methylenedioxy)phenyl]-1-propene, 5-(prop-2-en-1-yl)-2H-1,3-benzodioxole, DSSTox_CID_1254, DSSTox_RID_76041, DSSTox_GSID_21254, CAS-94-59-7, [1,2-(Methylenedioxy)-4-allyl]benzene, Rhyuno, 4-Allyl-procatecol, Spectrum_001446, Safrole, >=97%, 1, 5-allyl-, Spectrum2_000775, Spectrum3_001105, Spectrum4_001939, Spectrum5_000843, AC1L1JP9, 1, 5-(2-propenyl)-, 5-allyl-1,3-benzodiox ole, 5-allyl-benzo[1,3]dioxole, SCHEMBL56828, BSPBio_002810, KBioGR_002319, KBioSS_001926, 5-19-01-00553 (Beilstein Handbook Reference), MLS001056251, DivK1c_001022, SPECTRUM1503620, SPBio_000850, 3,4-Methylenedioxy-allybenzene, 4-allylcatechol methylene ether, CHEMBL242273, ZINC2050, 5-?Allyl-?1,3-?benzodioxole, DTXSID0021254, SCHEMBL13045858, Benzodioxole, 5-(2-propenyl)-, CTK5H6850, HMS503M05, KBio1_001022, KBio2_001926, KBio2_004494, KBio2_007062, KBio3_002030, NINDS_001022, 5-prop-2-enylbenzo[1,3]dioxole, HMS1922E22, 3, 4-(Methylenedioxy)allylbenzene, 4-allylpyrocatechol methylene ether, 3,4-methylenedioxyphenyl-2-propene, NSC11831, 1,2-methylenedioxy-4-allyl-Benzene, 1-Allyl,3,4-methylenedioxy benzene, Tox21_202439, Tox21_300520, NSC-11831, 1,2-(Methylenedioxy)-4-allylbenzene, 3-Allyl-1,2-(methylenedioxy)benzene, WLN: T56 BO DO CHJ G2U1, (E)5-1-Propenyl]-1,3-benzodioxole, AKOS016017163, 1, 2-(Methylenedioxy)-4-allylbenzene, 4-?Allyl-?1,2-?methylenedioxybenzene, 4-Allyl-1, 2-(methylenedioxy)benzene, 4-Allyl-1,2-(methylenedioxy)-benzene, 5-Allyl-1,3-benzodioxolerlet DS Base, CCG-214763, FCH3411428, FS-3451, LS-1965, SDCCGMLS-0066708.P001, 3-(3,4-methylendioxyphenyl)-1-propene, IDI1_001022, 4-Allyl-1,2-(methylened ioxy)-benzene, NCGC00091122-01, NCGC00091122-02, NCGC00091122-03, NCGC00091122-04, NCGC00091122-05, NCGC00091122-06, NCGC00254416-01, NCGC00259988-01, AN-24294, CC-34344, SC-75261, SMR001216599, ZB000468, 5-(2-Propenyl)-1,3-benzodioxole, 9CI, 1-ALLYL-3,4-METHYLIDENEDIOXYBENZENE, 4-Allyl-1,2-(methylenedioxy)benzene, 8CI, DB-057512, FT-0606467, S0002, ST50406117, 10024-001a, C10490, C-30422, SR-05000002392, Safrole, certified reference material, TraceCERT(R), SR-05000002392-1, BENZENE,1-ALLYL,3,4-METHYLENEDIOXY SAFROLE, I14-56876, F0000-0021, 4-I(c)+/-u>>u-1,2-NC(1/4)x>>u paragraph signthornNo>>u+/-(1/2), 5-I(c)+/-u>>u-1,3-+/-(1/2)(2) cent paragraph signthorndouble daggerfA, InChI=1/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2,4-6H,1,3,7H, 1406-55-9, 8022-92-2

ID: 2828

chemical graph of compound 2828



InChIKey: ZMRUPTIKESYGQW-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 62882
synonyms found at PubChem are:
Propranolol hydrochloride, 318-98-9, Propranolol Hcl, Inderal, Avlocardyl, Herzbase, Inderalici, Naprilin, Pronovan, Dociton, Ikopal, Kemi, Beta Neg, InnoPran XL, Anapriline, Propranolol chloride, Anaprilin, Berkolol, Caridolol, Inderex, 3506-09-0, Indermigran, Proprahexal, Propranovitan, Angilol, Apsolol, Arcablock, Artensol, Beprane, Biocard, Blocaryl, Cardinol, Corbeta, Deralin, Detensol, Dibudinate, Dumopranol, Duranol, Efectolol, Emforal, Farprolol, Frekven, Hemipralon, Indobloc, Kidoral, Nelderal, Noloten, Novopranol, Panolol, Prandol, Propabloc, Propadex, Propalong, Propayerst, Prophylux, Propral, Propranur, Pylapron, Rapynogen, Sagittol, Sawatol, Scandrug, Sloprolol, Sudenol, Tensiflex, Tiperal, Acifol, Cinlol, Ciplar, Elbrol, Herzul, Oposim, Pranix, Procor, Prosin, Tesnol, Nedis, Sinal, Tonum, Half-Inderal, Propranolol.HCl, Prano-Puren, Propanolol hydrochloride, propra vt ct, Inderal La, Proberta LA, Pur-Bloka, beta-NEG, Obsidan, R+C5989educor, NSC-91523, 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride, propranolol (hydrochloride), 1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride, ICI 45520, CCRIS 1105, Beta-Tablinen, Beta-Timelets, HSDB 3176, (+/-)-Propranolol, Hydrochloride, DL-Propranolol hydrochloride, EINECS 206-268-7, I 2065, AY 64043, 1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol hydrochloride, Efektolol, Inderol, Migrastat, Pranolol, ICI-45520, IN1139, AY-64043, 1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride, 1-(Isopropylamino)-3-(alpha-naphthoxy)-2-propanol hydrochloride, (??)-Propranolol HCl, DSSTox_CID_1198, Inderal hydrochloride, 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, hydrochloride, C16H22ClNO2, DSSTox_RID_76007, C16H21NO2.HCl, DSSTox_GSID_21198, 1-Isopropylamino-3-(1-naphthoxy)-propan-2-ol-hydrochloride, Q-201632, W-109142, Propranolol Hcl Intensol, 1-(1-Naphthyloxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, (+-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride, (2-Hydroxy-3-(naphthyloxy)propyl)isopropylammonium chloride, Hemangeol, Innopran, Propraratiopharm, (+/-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol, HCl, 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride, DL-Anapriline, 1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride, CHEBI:8500, 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, hydrochloride, (+-)-, CPD000059167, SMR000059167, NSC91523, Inderal (TN), Innopran XL (TN), SR-01000075285, PROPRANOLOL HYDROCHLORIDE (+/-), (R)-Propranolol hydrochloride, d,l-Propranolol hydrochloride, PROPRANOLOLHYDROCHLORIDE, 1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride, Tev-Tropin, Propranolol hydrochloride intensol, Relax-B, EINECS 222-501-5, NSC 91523, Propranolol hydrochloride [USAN:JAN], Propranolol hydrochloride [USAN:USP:JAN], Propranolon hydrochloride, CAS-318-98-9, AC1L1XZ4, CHEMBL1671, SCHEMBL41688, (y)-Propranolol hydrochloride, MLS000859628, MLS001055449, MLS001056753, MLS002222321, MLS002548855, (?)-Propranolol hydrochloride, ARONIS24408, SPECTRUM1505270, Jsp005924, Propranolol hydrochloride, 99%, DTXSID3021198, CTK3J2636, (+/-)-Propranolol hydrochloride, BBC/572, MolPort-001-759-087, ZMRUPTIKESYGQW-UHFFFAOYSA-N, HMS1570P06, HMS1571G12, HMS1571I04, HMS1922P19, Pharmakon1600-01505270, ACT02695, BCP15350, EUR-1000, HY-B0573, KDM-1102, KS-00000V0D, ZX-AS004773, Tox21_201886, Tox21_302905, Tox21_500896, 4289AB, ACM318989, ANW-62232, BG0302, CCG-39239, CCG-39447, GP3553, MFCD00012558, NSC758950, s4076, SBB080817, 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride, (+-)-, AKOS005267141, Propranolol hydrochloride (JP17/USP), CHM0004159, CS-2680, KS-1097, LP00896, LS-7676, MCULE-6124856976, NC00687, NSC-758950, RTR-013480, NCGC00024690-04, NCGC00091932-01, NCGC00094212-01, NCGC00094212-02, NCGC00094212-03, NCGC00094212-04, NCGC00094212-05, NCGC00256554-01, NCGC00259435-01, NCGC00261581-01, AN-23392, CC-33976, SAM002264638, SAM002699889, SC-15116, AB0011639, AX8233861, KB-215769, TL8002432, TR-013480, EU-0100896, FT-0603377, FT-0635178, P0995, ST50319806, WLN: L66J BO1YQ1MY1 & 1 & GH, BIM-0050871.0001, C-4618, D00483, J10004, P 0884, ( inverted question mark)-Propranolol hydrochloride, I14-2718, SR-01000075285-1, SR-01000075285-3, Z90121066, (+/-)-Propranolol hydrochloride, >=99% (TLC), powder, 1-[(methylethyl)amino]-3-naphthyloxypropan-2-ol, chloride, 3-[(methylethyl)amino]-1-naphthyloxypropan-2-ol, chloride, (+/-)-Propranolol hydrochloride, analytical reference material, 1-(Isopropylamino)-3-(1-napthyloxy)-2-propanol hydrochloride, Propranolol Hydrochloride 1.0 mg/ml in Methanol (as free base), (+/-)-[2-Hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride, (+/-)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, 1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane hydrochloride, 1-(1-naphthyloxy)-2-hydroxy-3-isopropylaminopropanehydrochloride, 1-(alpha-naphthoxy)-3-(iso-propylamino)-2-propanol hydrochloride, 1-(alpha-naphthoxy)-3-(isopropylamino)-2-propanol hydrochloride, 1-(Isopropylamino)-3-(.alpha.-naphthoxy)-2-propanol hydrochloride, 1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol hydrochloride, 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol hydrochloride, Propranolol hydrochloride, European Pharmacopoeia (EP) Reference Standard, ( inverted question mark)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride, (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride, Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard, 146874-86-4, Propranolol hydrochloride for performance test, European Pharmacopoeia (EP) Reference Standard, 3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol hydrochloride, AKOS026749955, MolPort-000-795-663

ID: 2829

chemical graph of compound 2829



InChIKey: ZMRUPTIKESYGQW-UQKRIMTDSA-N
SMILES: CC(C)NC[C@@H](COC1=CC=CC2=CC=CC=C21)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 165193
synonyms found at PubChem are:
(S)-(-)-Propranolol hydrochloride, 4199-10-4, (S)-Propranolol hydrochloride, UNII-YP6GDU0L78, YP6GDU0L78, (S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride, EINECS 224-096-0, MFCD00064547, (S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, (S)-(2-Hydroxy-3-(naphthyloxy)propyl)isopropylammonium chloride, 2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride (1:1), (2S)-, SR-01000076087, (S)-Propranolol HCl, PubChem11059, AC1Q3DQZ, l-Propranolol Chlorhydrate, (2s)-1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride, l-Propranolol Hydrochloride, AC1L4W8U, Levopropranolol hydrochloride, SCHEMBL41689, MLS000859887, SPECTRUM1500514, (-)-Propranolol Hydrochloride, CHEMBL545328, CTK4I5507, L-(-)-Propranolol Hydrochloride, Propranolol hydrochloride, (-)-, MolPort-002-051-398, (S)-()-Propranolol hydrochloride, HMS1920L20, Pharmakon1600-01500514, Tox21_501023, (2S)-(-)-Propanolol Hydrochloride, 4395AH, BG0413, NSC757295, AKOS015960770, API0000929, CCG-212772, LP01023, NSC-757295, VC30037, VC30279, NCGC00261708-01, AC-12294, SMR000326749, AX8048175, LS-184130, B6466, EU-0101023, ST24035739, P 8688, C-18535, SR-01000597856, SR-01000076087-1, SR-01000076087-5, SR-01000076087-6, SR-01000597856-1, (S)-(-)-Propranolol hydrochloride, >=98% (TLC), powder, UNII-F8A3652H1V component ZMRUPTIKESYGQW-UQKRIMTDSA-N, S-(-)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol Hydrochloride, (2S)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride (1:1), (2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol hydrochloride, (2S)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol hydrochloride, (2S)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol Hydrochloride, (S)-(-)-1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride, 2-Propanol,1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride (1:1), (2R)-

ID: 2830

chemical graph of compound 2830



InChIKey: ZMZGIVVRBMFZSG-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=O)NN)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 1742
synonyms found at PubChem are:
4-hydroxybenzhydrazide, 4-Hydroxybenzohydrazide, 5351-23-5, 4-Hydroxybenzoic acid hydrazide, 4-Hydroxybenzoic hydrazide, p-Hydroxybenzhydrazide, p-Hydroxybenzoic acid hydrazide, 4-Hydroxybenzoylhydrazine, Benzoic acid, 4-hydroxy-, hydrazide, p-Hydroxybenzoic hydrazide, (p-Hydroxybenzoyl)hydrazine, 4-Hydroxy-benzoic acid hydrazide, NSC 647, p-hydroxybenzoylhydrazine, Benzoic acid, p-hydroxy-, hydrazide, (4-Hydroxybenzoyl)hydrazine, CHEMBL124267, ZMZGIVVRBMFZSG-UHFFFAOYSA-N, 4-???phenol, EINECS 226-326-5, PubChem3885, 4-hydroxy benzhydrazide, 4OHPhCON2, 4-hydroxy-benzohydrazide, 4-hydroxybenzo hydrazide, AC1Q5ECZ, Lopac-H-9882, p-Hydroxybenzoyl hydrazide, 4-hydroxybenzoate hydrazide, ACMC-209l8c, benzoylhydrazine, P-hydroxy, AC1Q54TX, Lopac0_000568, Oprea1_145739, SCHEMBL80530, KSC490O5F, MLS002153529, 4-HYDROXY BENZHYRAZIDE, AC1L1C50, NSC647, PARAGOS 530170, 4-Hydroxybenzhydrazide, >=97%, 4-Hydroxybenzoic acid, hydrazide, CTK3J0752, TIMTEC-BB SBB043780, DTXSID90201721, NSC-647, ATTERCOP-CHM AT112837, MolPort-000-183-230, para-Hydroxybenzoic acid hydrazide, HMS3062I15, HMS3261B18, ZINC122698, ART-CHEM-BB ACB003095, ACT08149, ALBB-001058, KS-00000W8E, AKOS BBS-00008116, Tox21_500568, AKOS A1230-0374, AN-271, ANW-31786, BBL008415, BDBM50320734, HTS001729, LABOTEST-BB LT00053673, MFCD00007605, SBB043780, STK076141, AKOS000119735, AS00896, BS-3839, CCG-204657, LP00568, MCULE-1791196578, RTR-018931, TRA0059153, VZ36759, NCGC00015528-01, NCGC00015528-02, NCGC00015528-03, NCGC00015528-04, NCGC00093952-01, NCGC00093952-02, NCGC00261253-01, AJ-11811, CJ-00926, KB-85972, KB-98144, SC-73730, SMR000247649, ZB004231, AB0012918, AB1008043, DB-052349, KB-192714, TR-018931, Benzoic acid, 4-hydroxy-, hydrazide (9CI), Benzoic acid, p-hydroxy-, hydrazide (8CI), EU-0100568, FT-0618692, ST50046190, A-7968, H 9882, 4-Hydroxybenzohydrazide (p-Hydroxybenzohydrazide), SR-01000075923, I02-1418, SR-01000075923-1, 4-Hydroxybenzhydrazide, suitable for fluorescence, >=97.0% (T), 4-Hydroxybenzoylhydrazine; p-Hydroxybenzoic acid hydrazide; 4-Hydroxybenzoic hydrazide

ID: 2831

chemical graph of compound 2831



InChIKey: ZNIFSRGNXRYGHF-UHFFFAOYSA-N
SMILES: C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 20179
synonyms found at PubChem are:
CLONIDINE HYDROCHLORIDE, 4205-91-8, Clonidine HCl, Catapres, 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride, Chlophazolin, Dispaclonidin, Normopresan, Atensina, Barclyd, Capresin, Caprysin, Catanidin, Clofelin, Clonilou, Clonisin, Clonistada, Edolglau, Glausine, Haemiton, Ipotensium, Katapresan, Klophelin, Iporel, Kapvay, Apo-Clonidine, Clonidil-Riker, Novo-Clonidine, Clonid-Ophal, Nu-Clonidine, N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride, ST-155, clonidine (hydrochloride), Clonidine monohydrochloride, UNII-W76I6XXF06, EINECS 224-121-5, C9H9Cl2N3.HCl, W76I6XXF06, DICHLORANILINO IMIDAZOLIN, Clonidine hydrochloride (Catapres), 2-((2,6-Dichlorophenyl)amino)-2-imidazoline hydrochloride, 2-((2,6-Dichlorophenyl)imino)imidazolidine monohydrochloride, 2-Imidazoline, 2-(2,6-dichloroanilino)-, monohydrochloride, 2-(2,6-Dichlorophenylamino)-2-imidazolin hydrochlorid [German], Catapres (TN), 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- [CAS], Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, hydrochloride, Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride, 2-(2,6-Dichlorophenylamino)-2-imidazoline Hydrochloride, Isaglaucon, Bapresan, Clonicel, Haemitom, Trialox, SMR000466276, 205C918, SR-01000075246, CAS-4205-91-8, (2,6-dichlorophenyl)-2-imidazolin-2-ylamine, chloride, N-(2,6-dichlorophenyl)imidazolidin-2-imine;hydrochloride, Jenloga, clonidine-hcl, SR-01000759380, Prestwick_73, 4,5-dihydro-, Clonidine hydrochloride [USAN:BAN:JAN], AC1L2FPH, Clonidine hydrochloride [USAN:USP:BAN:JAN], ACMC-209jn5, AC1Q3B9Y, N-(2,6-dichlorophenyl)-, CHEMBL1705, Clonidine Hydrochloride,(S), DSSTox_CID_24670, DSSTox_RID_80388, DSSTox_GSID_44670, SCHEMBL40751, MLS000758256, MLS001424222, ARONIS24351, Clonidine hydrochloride, solid, 2-(2,6-Dichlorophenylamino)-2-imidazolin hydrochlorid, CHEBI:3758, DTXSID8044670, CTK8B1674, HY-B0409A, KS-00000XRG, 4205-90-7 (Parent), MolPort-001-684-471, MolPort-003-928-972, ZNIFSRGNXRYGHF-UHFFFAOYSA-N, HMS1568B18, Pharmakon1600-01500198, BCP14375, Tox21_301552, Tox21_500268, ANW-29727, BDBM50020341, CCG-40087, Clonidine hydrochloride (JP17/USP), MFCD00036705, NSC756699, s2458, SBB003065, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride, AKOS005267207, AKOS024458609, AKOS028114993, ACN-034830, CCG-101051, CCG-212540, CCG-229466, CS-2509, KS-1253, LP00268, MCULE-6555265624, NC00301, NSC-756699, VA10617, NCGC00093726-01, NCGC00093726-02, NCGC00180902-01, NCGC00256172-01, NCGC00260953-01, AC-10306, AC-29742, AN-18868, BC204172, CPD000466276, H535, LS-79607, SAM001247073, SC-16715, ST088475, AB1009402, Clonidine hydrochloride, >=98.0% (TLC), KB-166292, RT-004883, D1353, EU-0100268, FT-0601096, C 7897, D00604, J10306, M-1457, A825736, I14-070, I14-0070, Q-200880, SR-01000075246-1, SR-01000075246-3, SR-01000759380-5, 2-[(2,6-dichlorophenyl)imino]imidazolidine hydrochloride, 2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE HYDROCHLORID, 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride, Clonidine Hydrochloride 1.0 mg/ml in Methanol (as free base), Clonidine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Clonidine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Clonidine hydrochloride, United States Pharmacopeia (USP) Reference Standard, N-(2,6-DICHLOROPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-2-AMINE HCL, 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-, monohydrochloride (9CI), N-[2,6-bis(chloranyl)phenyl]-4,5-dihydro-1H-imidazol-2-amine hydrochloride, 57665-50-6, 64638-22-8, 66009-47-0, 66073-52-7, 73121-65-0, 7555-15-9, Clonidine HCI, AC1Q1SX8, AKOS026750072

ID: 2832

chemical graph of compound 2832



InChIKey: ZNRYCIVTNLZOGI-UHFFFAOYSA-N
SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 108047
synonyms found at PubChem are:
ML-9, 105637-50-1, ML 9, ML-9, Hydrochloride, UNII-BZ2L6JK93I, ML 9 hydrochloride, 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine HCl, BZ2L6JK93I, IN1221, 1-(5-Chloronaphthalenesulfonyl)homopiperazine hydrochloride, 1-(5-chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine, 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride, 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl, 1-(5-chloronaphthalen-1-ylsulfonyl)-1,4-diazepane hydrochloride, 1-((5-Chloronaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride, 1H-1,4-Diazepine, 1-((5-chloro-1-naphthalenyl)sulfonyl)hexahydro-, monohydrochloride, SR-01000075741, ML-9 hydrochloride, C15H17ClN2O2S.HCl, BMK1-E7, AC1L338K, SCHEMBL1848494, CHEMBL1257075, CTK8E8325, DTXSID60147228, OR7351T, MolPort-001-769-947, ZX-AT008912, Tox21_500209, MFCD00065525, NSC734549, AKOS022180145, ML-9, >=99% (TLC), powder, CCG-221513, LP00209, NSC-734549, VZ20991, NCGC00093681-01, NCGC00260894-01, CC-02396, KB-147534, LS-171976, RT-013917, B6300, EU-0100209, FT-0642604, C 1172, K00008, C-20914, J-001466, SR-01000075741-1, SR-01000075741-3, 1-(5-CHLORONAPHTHALENE-SULFONYL)HOMOPIPERAZINE, 1-(5-chloronaphthalenesulfonyl)homo piperazine hydrochloride, ML-9; 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl, 1-(5-chloronaphthalen-1-yl)sulfonyl-1,4-diazepane hydrochloride, 1-(5-Chloronaphthalenesulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride, 1-(5-Chloronaphthalenesulphonyl)-1H-hexahydro-1,4-diazepine hydrochloride [ML-9], 1H-1,4-Diazepine,1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-, hydrochloride (1:1)

ID: 2833

chemical graph of compound 2833



InChIKey: ZNWMRWWNJBXNKJ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5702295
synonyms found at PubChem are:
Benzamil hydrochloride, Benzylamiloride hydrochloride, 161804-20-2, 2898-76-2, UNII-I7L324A070, I7L324A070, N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride, SMR000326882, SR-01000075711, Benzamil HCl, Benzamil*HCl, Prestwick_985, AC1NWAZ2, MLS000860024, MLS002153339, MLS002153937, SPECTRUM2300179, SCHEMBL9464171, CHEMBL1256878, CTK8F7959, HY-B1546A, MolPort-035-765-689, HMS1570C15, BCP20263, EX-A1706, Tox21_500211, AKOS024457593, ACM2898762, CCG-220657, CCG-221515, CS-7692, LP00211, NCGC00093683-01, NCGC00093683-02, NCGC00093683-03, NCGC00093683-04, NCGC00178271-01, NCGC00178271-02, NCGC00260896-01, B7391, EU-0100211, B 2417, J-009861, J-017341, SR-01000075711-1, SR-01000075711-4, 3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride, 3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride, 3,5-diamino-N-[amino(benzylamino)methylidene]-6-chloropyrazine-2-carboxamide hydrochloride, (E)-3,5-diamino-N-(amino(benzylamino)methylene)-6-chloropyrazine-2-carboxamide hydrochloride, 2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-(imino((phenylmethyl)amino)methyl)-, hydrochloride (1:1)

ID: 2834

chemical graph of compound 2834



InChIKey: ZOCUOMKMBMEYQV-GSLJADNHSA-N
SMILES: CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 224246
synonyms found at PubChem are:
ISOFLUPREDONE ACETATE, 338-98-7, Predef, 9-Fluoroprednisolone acetate, Biorinil, 9-Fluoroprednisolone 21-acetate, U-6013, Isoflupredone 21-acetate, UNII-55P9TUL75S, U 6013, Predef R 2X, Predef 2X, NSC 12600, NSC 37977, MLS002154168, 55P9TUL75S, CHEBI:34517, 9-Fluorprednisolone acetate, Predef (Veterinary), 9alpha-Fluoroprednisolone acetate, Prednisolone, 21-acetate, 9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, DSSTox_CID_25306, DSSTox_RID_80792, DSSTox_GSID_45306, Predef, veterinary, EINECS 206-423-9, Prednisolone, 9-fluoro-, 21-acetate, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11beta)-, Isoflupredone acetate (USAN), MLS002701905, deltarhinol, 9.alpha.-Fluoroprednisolone acetate, NSC12600, NSC37977, 9-Fluoro-11.beta.,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, Pregna-1,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-, 21-acetate, 9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, Pregna-1,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.)-, 9.alpha.-Fluoroprednisolone 21-acetate, Isoflupredone acetate [USAN:USP], NCGC00016433-01, 7793-38-6, CAS-338-98-7, Prestwick0_000006, Prestwick1_000006, Prestwick2_000006, Prestwick3_000006, AC1L5D5K, SCHEMBL42746, BSPBio_000011, SPBio_001932, 9|A-Fluoroprednisolone Acetate, BPBio1_000013, CHEMBL1608183, DTXSID3045306, Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-, 21-acetate, HMS1568A13, HMS2095A13, HMS2230O19, HMS3712A13, 9|A-Fluoroprednisolone 21-Acetate, BCP11877, ZINC4213604, Tox21_110437, 9alpha-Fluoroprednisolone 21-acetate, NSC-12600, NSC-37977, AKOS025402238, Tox21_110437_1, AC-6833, AN-9612, API0010029, CCG-220006, NCGC00179685-01, NCGC00179685-03, NCI60_000602, NCI60_003588, SMR001233466, AB2000747, AB00513794, C14636, D04627, 338I987, Q-101369, 21-Acetoxy-9-fluoro-11|A,17-dihydroxypregna-1,4-diene-3,20-dione, 21-Acetoxy-9-fluoro-11beta,17-dihydroxypregna-1,4-diene-3,20-dione, 9-Fluoro-11|A,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-Acetate, 9|A-Fluoro-11|A,17|A,21-trihydroxypregna-1,4-diene-3,20-dione 21-Acetate, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-, 21-acetate (8CI), [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate, [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-, 21-acetate (6CI,7CI,8CI)

ID: 2835

chemical graph of compound 2835



InChIKey: ZOCXUHJGZXXIGQ-NPXWYGMKSA-N
SMILES: CC(C)CCCCCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 56927836
synonyms found at PubChem are:
tunicamycin B, tunicamycin VII, Tunicamycin C1, UNII-6SE66719OT, 6SE66719OT, 66081-36-5, (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-14-methylpentadec-2-enamide, (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(14-methylpentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine, Corynetoxin U-16I, TUNICAMYCIN C1 HOMOLOG, CHEBI:64256, ZINC96085314, B7417, UNII-55W4525Q2E component ZOCXUHJGZXXIGQ-NPXWYGMKSA-N

ID: 2836

chemical graph of compound 2836



InChIKey: ZOEFQKVADUBYKV-MCDZGGTQSA-N
SMILES: C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6419976
synonyms found at PubChem are:
Adenosine 5'-monophosphate monohydrate, 18422-05-4, Adenosine-5'-monophosphate monohydrate, ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate hydrate, Adenosine-5-monophosphate, Prestwick_546, A-5'-P, AC1O4WHA, MLS001306420, SCHEMBL968911, CHEMBL1315633, C10H16N5O8P, CTK0H6998, HY-A0181A, BIB3002, MolPort-003-925-190, ZX-AFC000582, adenosine 5'-monophosphate hydrate, adenosine-5'-phosphate monohydrate, HMS1569G13, HMS2096G13, HMS2232G19, HMS3713G13, Adenosine 5'-monophosphate free acid, MFCD00005750, AKOS025310791, CCG-220356, CS-8159, RTR-008499, SMR000718790, U657, (-)-Adenosine 5'-monophosphate monohydrate, KB-200372, TR-008499, ST24045921, A-7264, SR-01000837507, SR-01000837507-2, Adenosine 5'-monophosphate monohydrate, from yeast, >=97%, Adenosine 5'-monophosphate monohydrate, from yeast, >=99%, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate hydrate

ID: 2837

chemical graph of compound 2837



InChIKey: ZOGNBLKDKPCKGB-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)CC=C)OC(=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 62362
synonyms found at PubChem are:
Eugenyl benzoate, 4-Allyl-2-methoxyphenyl benzoate, Eugenol benzoate, Benzoyl eugenol, p-Eugenol, benzoate, 531-26-0, UNII-YRO21E9Z35, PHENOL, 2-METHOXY-4-(2-PROPENYL)-, BENZOATE, Phenol, 4-allyl-2-methoxy-, benzoate, Phenol, 2-methoxy-4-(2-propen-1-yl)-, 1-benzoate, 2-Methoxy-4-(2-propenyl)phenyl benzoate, YRO21E9Z35, 2-methoxy-4-(prop-2-en-1-yl)phenyl benzoate, Phenol, 4-allyl-2-methoxy-, benzoate (8CI), Eugenyl Benzoat, FEMA No. 2471, EINECS 208-504-4, NSC 408913, Spectrum_000718, SpecPlus_000268, AI3-23236, AC1L1WYY, Spectrum2_001905, Spectrum3_001313, Spectrum4_001465, Spectrum5_000109, Oprea1_410467, BSPBio_003005, KBioGR_002009, KBioSS_001198, SPECTRUM300157, MLS001049077, DivK1c_006364, SCHEMBL357066, SPBio_001870, CHEMBL264141, FEMA 2471, KBio1_001308, KBio2_001198, KBio2_003766, KBio2_006334, KBio3_002225, MolPort-000-716-472, ZOGNBLKDKPCKGB-UHFFFAOYSA-N, HMS2268G13, ZINC519080, CCG-38476, NSC408913, (4-allyl-2-methoxy-phenyl) benzoate, AKOS030490315, benzoic acid eugenyl ester, AldrichCPR, MCULE-4240897420, NSC-408913, SDCCGMLS-0066560.P001, NCGC00095927-01, NCGC00095927-02, AN-23547, SMR000386915, (2-methoxy-4-prop-2-enylphenyl) benzoate, AE-562/13525005, SR-01000758224, SR-01000758224-2

ID: 2838

chemical graph of compound 2838



InChIKey: ZOMSMJKLGFBRBS-UHFFFAOYSA-N
SMILES: CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2328
synonyms found at PubChem are:
Bentazone, bentazon, Basagran, 25057-89-0, Bendioxide, Leader, Basagran 480, Pentazone, Laddok, Pledge, Basagran-plus, Graminon-plus, Basagran M, Basagran KV, 1H-2,1,3-Benzothiadiazin-4(3H)-one, 3-(1-methylethyl)-, 2,2-dioxide, Bentazon [ANSI], Caswell No. 509C, BAS 351H, Bentazone [BSI:ISO], BAS 3510H, BAS 3512H, BAS 3517H, UNII-R4S7ZGZ9CT, BAS 3510, BAS 351-07H, CCRIS 6977, BAS 351-H, HSDB 3430, EINECS 246-585-8, R4S7ZGZ9CT, 3-Isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one-2,2-dioxide, EPA Pesticide Chemical Code 275200, 1H-2,1,3-Benzothiadiazin-4(3H)-one, 3-isopropyl-, 2,2-dioxide, BRN 0530220, CHEBI:3018, ZOMSMJKLGFBRBS-UHFFFAOYSA-N, 3-Isopropyl-2,1,3-benzothiadiazinon-(4)-2,2-dioxid, 3-Isopropyl-4H-2,1,3-benzothiadiazin-4-one 2,2-dioxide, 3-Isopropyl-1H-benzo-2,1,3-thiadiazin-4-one 2,2-dioxide, 3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide, 3-Isopropyl-2,1,3-benzothiadiazinon-(4)-2,2-dioxid [German], 1H-2,1,3-Benzothiadiazin-4(3H)-one-2,2-dioxide, 3-isopropyl-, 3-(1-Methylethyl)-(1H)-2,1,3-benzothiadiazin-4(3H)-one-2,2-dioxide, DSSTox_CID_3901, DSSTox_RID_77225, DSSTox_GSID_23901, Basamais, Bazargan, Adagio, Corsar, bentazon(basagran), CAS-25057-89-0, 2,2-dioxo-3-propan-2-yl-1H-2?^{6},1,3-benzothiadiazin-4-one, BENTASON, Spectrum_001851, BASAGRAN(R), SpecPlus_000462, AC1L1DFL, AC1Q6FGA, Spectrum2_001889, Spectrum3_000831, Spectrum4_000671, Spectrum5_001976, Oprea1_558180, Oprea1_729468, SCHEMBL53939, Bentazon, analytical standard, BSPBio_002381, KBioGR_001101, KBioSS_002368, SPECTRUM330039, DivK1c_006558, SPBio_001798, CHEMBL1567045, DTXSID0023901, CTK4F4881, KBio1_001502, KBio2_002364, KBio2_004932, KBio2_007500, KBio3_001881, ZOMSMJKLGFBRBS-UHFFFAOYSA-, BCP27977, Tox21_201951, Tox21_300742, CCG-15052, ZINC95630288, 1H-2,1,3-Benzothiadiazin-4(3H)-one, 3-isopropyl-, 2,2-dioxide (8CI), 3-(1-METHYLETHYL)-1H-2,1,3-BENZOTHIADIAZIN-4(3H)-ONE 2,2-DIOXIDE, 50723-80-3 (hydrochloride salt), AKOS015897484, JC10172, RTR-011473, 1H-2,1,3-Benzothiadiazin-4(3H)-one, 3-(1-methylethyl)-, 2,2-dioxide (9CI), 3-(1-Methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide (8CI)(9CI), Bentazone 10 microg/mL in Acetonitrile, Bentazone 100 microg/mL in Acetonitrile, NCGC00094531-01, NCGC00094531-02, NCGC00094531-03, NCGC00094531-04, NCGC00094531-05, NCGC00094531-06, NCGC00094531-07, NCGC00254648-01, NCGC00259500-01, AN-17527, CC-24281, LS-40458, O666, SC-81110, TR-011473, Bentazon, PESTANAL(R), analytical standard, FT-0638490, C10965, 057B890, A817619, C-24262, SR-01000388483, I09-1325, SR-01000388483-1, 3-isopropyl-2,1,3-benzothiadiazin-4-one-2,2-dioxide, BRD-K33986892-001-02-3, 3-Isopropyl-4-oxo-2,1,3-benzothiadiazine 2,2-dioxide, 3-isopropyl-2,2-dioxo-1H-2$l;{6},1,3-benzothiadiazin-4-one, 3-isopropyl-2,2-dioxo-1H-2$l^{6},1,3-benzothiadiazin-4-one, 2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one, 2,2-dioxo-3-propan-2-yl-1H-benzo[d][1,2,6]thiadiazin-4-one, 3-(1-Methylethyl)-2,1,3-benzothiadiazin-4(3H)-one 2,2-Dioxide, 3-(propan-2-yl)-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide, 2-ISO-PROPYL-(1H)-BENZO-2,1,3-THIADIAZIN 4-ONE-2,2-DIOXIDE, 3,4-Dihydro-3-isopropyl-1H-2,1,3-benzothiadiazin-4-one 2,2-Dioxide, 3-(1-Methylethyl)-1H-2,1,3-benzothia-diazin-4(3H)-one 2,2-dioxide, 3-(1-methylethyl)-1H-2,1,3-benzothiadiazin- -4 (3H)-one-2,2-dioxide, 3-(1-methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one- -2,2-dioxide, 3-(1-methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one-2,2-dioxide, 2,2-bis(oxidanylidene)-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one, 3-(1-Methylethyl)-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide (8CI), 12705-05-4, 21723-40-0, 58856-82-9, InChI=1/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3

ID: 2839

chemical graph of compound 2839



InChIKey: ZONYXWQDUYMKFB-UHFFFAOYSA-N
SMILES: C1C(OC2=CC=CC=C2C1=O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 10251
synonyms found at PubChem are:
FLAVANONE, 487-26-3, 2-Phenylchroman-4-one, 2,3-Dihydroflavone, 2-Phenyl-4-chromanone, 4-Flavanone, 2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-2-phenyl-, 2-Phenyl-2,3-dihydro-4H-chromen-4-one, NSC-50393, 2,3-Dihydro-2-phenyl-4H-benzopyran-4-one, 2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one, 2-Phenyl-chroman-4-one, EINECS 207-654-8, NSC 50393, BRN 0183227, MLS002667384, CHEBI:5070, CHEMBL274318, ZONYXWQDUYMKFB-UHFFFAOYSA-N, NSC50393, 2-phenyl-2,3-dihydrochromen-4-one, (-)-Flavanone, SMR001306759, 2-Phenylchromanone, Flavanone, 98%, Spectrum_000081, SpecPlus_000724, AC1L1USZ, Spectrum2_000205, Spectrum3_000174, Spectrum4_001646, Spectrum5_000491, Flavone, 2,3-dihydro-, ACMC-1C3CR, D0B4VE, D0L3CJ, AC1Q6EE1, AC1Q6EE2, AC1Q6EE3, Oprea1_401736, SCHEMBL19745, BSPBio_001667, GTPL408, KBioGR_002111, KBioSS_000501, SPECTRUM200343, 5-17-10-00480 (Beilstein Handbook Reference), MLS002207195, DivK1c_006820, SPBio_000189, MEGxp0_001684, DTXSID9022318, ACon1_002246, FLAVANONE (3,3-D2), KBio1_001764, KBio2_000501, KBio2_003069, KBio2_005637, KBio3_001167, ZONYXWQDUYMKFB-UHFFFAOYSA-, MolPort-000-696-915, ANW-30691, BBL027613, BDBM50051358, CCG-21177, MFCD00006841, SBB042502, STL373060, AKOS000120276, AKOS016040110, MCULE-3925941144, NE10459, RTR-017732, VA10912, KS-0000121T, NCGC00095802-01, NCGC00095802-02, NCGC00095802-03, AS-48159, BAS 00733073, LS-68930, NCI60_004213, ST098942, TR-017732, 2-Phenyl-2,3-dihydro-4H-chromen-4-one #, EU-0012871, F0255, FT-0618436, Y2045, 4H-1-Benzopyran-4-one,3-dihydro-2-phenyl-, C00766, L000786, SR-01000500943, F4C11F5A-DFFA-4E0E-BCC9-2FD60204B2DD, SR-01000500943-1, (2RS)-2-Phenyl-2,3-dihydro-4H-1-benzopyran-4-one, BRD-A07824748-001-02-6, BRD-A07824748-001-03-4, I14-54589, Z57085783, 24271-98-5, InChI=1/C15H12O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-9,15H,10H2

ID: 2840

chemical graph of compound 2840



InChIKey: ZPAKPRAICRBAOD-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)CCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3335
synonyms found at PubChem are:
fenbufen, 36330-85-5, Lederfen, Cinopal, Bufemid, Napanol, 4-(4-Biphenylyl)-4-oxobutyric acid, 3-(4-Phenylbenzoyl)propionic acid, 3-(4-Biphenylylcarbonyl)propionic acid, 4-(biphenyl-4-yl)-4-oxobutanoic acid, gamma-Oxo(1,1'-biphenyl)-4-butanoic acid, 3-(4-Biphenylcarbonyl)propionic acid, Cinopol, 4-oxo-4-(4-phenylphenyl)butanoic acid, Fenbufene [INN-French], Fenbufenum [INN-Latin], 4-([1,1'-biphenyl]-4-yl)-4-oxobutanoic acid, CL 82204, CL-82204, 4-biphenyl-4-yl-4-oxobutanoic acid, Butyric acid 4-(4-biphenyl)-4-oxo-, UNII-9815R1WR9B, MLS000069810, beta,p-Phenylbenzoylpropionic acid, Propionic acid, 3-(4-biphenylylcarbonyl)-, EINECS 252-979-0, BRN 2378560, Diphenyl-4-gamma-oxo-gamma-butyric acid, SMR000059150, CHEMBL277522, CHEBI:31599, ZPAKPRAICRBAOD-UHFFFAOYSA-N, 9815R1WR9B, 4-(4-biphenyl)-4-oxobutyric acid, (1,1'-BIPHENYL)-4-BUTANOIC ACID, gamma-OXO-, NCGC00016834-01, CAS-36330-85-5, DSSTox_CID_3043, 4-[1,1'-biphenyl-4-yl]-4-oxobutanoic acid, DSSTox_RID_76849, DSSTox_GSID_23043, Fenbufenum, Fenbufene, 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid, SR-01000721906, Fenbufen [USAN:BAN:INN:JAN], Fenbufen [USAN:INN:BAN:JAN], Fenbufen,(S), Prestwick_567, Fenbufen, 96%, Spectrum_001248, Opera_ID_464, Prestwick0_000218, Prestwick1_000218, Prestwick2_000218, Prestwick3_000218, Spectrum2_001389, Spectrum3_001430, Spectrum4_000411, Spectrum5_001528, D06LHG, AC1L1FP8, SCHEMBL25117, BSPBio_000235, BSPBio_003140, Fenbufen, analytical standard, KBioGR_000702, KBioSS_001728, [1,1'-Biphenyl]-4-butanoic acid, .gamma.-oxo-, 3-10-00-03334 (Beilstein Handbook Reference), MLS001074090, DivK1c_000025, SPECTRUM1501008, SPBio_001378, SPBio_002156, AC1Q754O, BPBio1_000259, Fenbufen (JP17/USAN/INN), ZINC1427, DTXSID9023043, HMS500B07, KBio1_000025, KBio2_001728, KBio2_004296, KBio2_006864, KBio3_002360, MolPort-001-788-506, NINDS_000025, HMS1568L17, HMS1921B13, HMS2090G14, HMS2092B03, HMS2095L17, HMS2235I24, HMS3372M18, HMS3712L17, Pharmakon1600-01501008, 4-biphenyl-4-yl-4-oxobutyric acid, BCP12106, HY-B1138, KS-00000CM9, .beta.,p-Phenylbenzoylpropionic acid, 3-(4-Phenyl)benzoyl propionic acid, Tox21_110638, BDBM50240374, CCG-38988, MFCD00056701, NSC757812, s4526, STK202178, 4-biphenyl-4-yl-4-oxo-butyric acid, 4-(Biphenyl-4-yl)-4-oxobutanoicAcid, 4-(biphenyl-4-yl)-4-oxobutyric acid, AKOS000200430, Tox21_110638_1, AN-4522, CS-4743, DB08981, MCULE-7151650091, NSC-757812, SS-4225, TRA0020080, 3-(4'-biphenylcarbonyl) propanoic acid, IDI1_000025, 3-(4-biphenylylcarbonyl) propionic acid, 3-(4-biphenylylcarbonyl)-propionic acid, NCGC00016834-02, NCGC00016834-03, NCGC00016834-04, NCGC00016834-07, NCGC00094886-01, NCGC00094886-02, NCGC00094886-03, AC-14459, AJ-08026, H787, LS-44188, SC-58146, SBI-0051631.P002, AB0013262, CL 82,204, TC-307545, AB00052195, BB 0221124, FT-0626394, gamma-oxo(1,1''-biphenyl)-4-butanoic acid, gamma-Oxo-(1,1'-biphenyl)-4-butanoic acid, .gamma.-Oxo(1,1'-biphenyl)-4-butanoic acid, Diphenyl-4-.gamma.-oxo-.gamma.-butyric acid, 4-[1,1''-biphenyl-4-yl]-4-oxobutanoic acid, D01344, J10171, K-8124, 4-[1,1'-Biphenyl]-4-yl-4-oxobutanoic acid #, AB00052195-13, AB00052195_14, I06-0354, SR-01000721906-2, SR-01000721906-4, SR-01000721906-5, BRD-K12513978-001-05-0, BRD-K12513978-001-16-7, Z99599540, Fenbufen, European Pharmacopoeia (EP) Reference Standard, N-(4-(piperidin-1-yl)phenethyl)-5-chloro-3-ethyl-1H-indole-2-carboxamide

ID: 2841

chemical graph of compound 2841



InChIKey: ZPBWCRDSRKPIDG-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 60496
synonyms found at PubChem are:
AMLODIPINE BESYLATE, 111470-99-6, Amlodipine besilate, Cardiorex, Amlodipine benzenesulfonate, Istin, Amdepin, Amdipin, Amlodin, Amlogard, Amlopin, Amlosyn, Antacal, Astudar, Cordarene, Monopina, Myodura, Norlopin, Norvask, Tensivask, Amcard, Norvas, Pelmec, Terloc, Amlodipine (besylate), 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate, Amlodipine besylate [USAN], CHEBI:2669, UK 48340-26, HSDB 7079, NCGC00095835-01, Amlodipine besylate (USAN), DSSTox_CID_23909, DSSTox_RID_80087, C26H31ClN2O8S, DSSTox_GSID_43909, 3-Ethyl 5-methyl (+-)-2-((2-aminoethoxy)methyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, monobenzenesulfonate, Q-101934, Q-200627, Stamlo, 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (+-)-, monobenzenesulfonate, 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl-5-methyl ester, monobenzenesulfonate, CAS-111470-99-6, MFCD00864687, NCGC00165957-04, r-amlodipine, Amlodipine besylate [USAN:USP], C20H25ClN2O5.C6H6O3S, 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate, Istin;Norvasc;Norvasc, Spectrum_000573, AC1L1TCT, AC1Q6WSZ, Amlodipine benzenesulphonate, D0H7WA, Amlodipine besilate (JP17), SCHEMBL41282, FCP-3P1, KBioSS_001053, MLS001361394, Amlodipine besylate (Norvasc), SPECTRUM1505202, amlodipine; benzenesulfonic acid, CHEMBL1200402, CHEMBL3193637, CHEMBL3207778, DTXSID2043909, HY-B0317B, KBio2_001053, KBio2_003621, KBio2_006189, AOB5215, MolPort-001-759-081, ZPBWCRDSRKPIDG-UHFFFAOYSA-N, HMS2094E13, HMS2232D22, HMS2235B19, HMS3269B19, HMS3372O18, HMS3373F15, Pharmakon1600-01505202, BCP21993, Amlodipine besylate, racemic mixture, Tox21_111525, Tox21_113476, AC-079, Antihyperlipidemic, Forbes Medi-Tech, CA0135, CCG-39531, MFCD00887594, NSC758922, s1813, AKOS001260256, AKOS016340493, Amlodipine besylate, >=98% (HPLC), AN-7254, API0005435, BCP9000059, CS-3988, KS-1029, MCULE-3638128556, NSC-758922, AK122586, SMR000875356, AB0012646, AB2000306, AX8246764, KB-295583, LS-131175, TL8000339, UK-48,340, FT-0082675, FT-0622301, UK-4834026, UK-48340-26, VU0244594-3, D00615, J10223, J10238, UK-48,340-26, 470A996, A802368, I06-0736, SR-05000001461-2, F6170-0024, Amlodipine besylate, European Pharmacopoeia (EP) Reference Standard, Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard, Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material, Amlodipine for peak identification, European Pharmacopoeia (EP) Reference Standard, (R,S,)3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulphonate, 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona, 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester; benzenesulfonic acid, 2-[(2-Aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate, 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate, 3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate, benzenesulfonic acid; 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, benzenesulfonic acid; O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, benzenesulfonic acid; O3-ethyl O5-methyl 2-(2-azanylethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

ID: 2842

chemical graph of compound 2842



InChIKey: ZPMVNZLARAEGHB-UHFFFAOYSA-N
SMILES: CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 13770
synonyms found at PubChem are:
cyproheptadine hydrochloride, Cyproheptadine Hcl, 969-33-5, Cipractin, Periactin hydrochloride, Anarexol, Antegan, Nuran, Periactin syrup, Peritol, component of Dronactin, Periactinol (VAN), Cyproheptadiene hydrochloride, Periactinol hydrochloride, Cyproheptadine chlorhydrate, Cycloheptadine hydrochloride, Cyproheptadine hydrochloride anhydrous, Cyproheptadine (hydrochloride), UNII-0S9323MCT0, VUFB3511, EINECS 213-535-1, NSC 169911, 41354-29-4, Cyproheptadine Hydrochloride (anhydrous), CPD000058431, AI3-26940, MLS000028462, CHEBI:59695, 0S9323MCT0, Cyproheptadine hydrochloride sesquihydrate, SMR000058431, 4-(5-Dibenzo(a,e)cycloheptatrienylidene)piperidine hydrochloride, 1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine hydrochloride, Piperidine, 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-, hydrochloride, W-106308, Contrallerg, Kulinet, Kyliver, Sialotin, Vinorex, Istam, C21H21N.HCl, 1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene) piperidinehydrochloride, 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride, SR-01000003077, 4-(5-Dibenzo[a,e]cycloheptatrienylidene)piperidine hydrochloride, 1-Methyl-4-(5-dibenzo[a,e]cycloheptatrienylidene)piperidine hydrochloride, Prestwick_139, Opera_ID_383, AC1Q3BNN, Cypoheptadine hydrochloride, Cyproheptadine-hydrochloride, AC1L22FV, AC1Q38XK, 969-33-5(anhydrous), CHEMBL1716, Cyproheptadine(hydrochloride), SCHEMBL41842, MLS001077277, MLS001424281, MLS002222173, REGID_for_CID_13770, Cyproptadine Hydrochloride,(S), DTXSID5042586, CTK8F8876, HY-B0366A, MolPort-003-940-781, ZPMVNZLARAEGHB-UHFFFAOYSA-N, HMS1568E08, Pharmakon1600-01505973, cyproheptadine hydrochloride (anh.), Tox21_500246, anhydrous cyproheptadine hydrochloride, BG0159, NSC169911, NSC759282, s2044, AKOS015905305, CCG-101144, CS-2423, LP00246, NC00394, NSC-169911, NSC-759282, Cyproheptadine hydrochloride (Periactin), KS-00001F75, NCGC00093708-01, NCGC00093708-02, NCGC00260931-01, AC-15790, AN-48180, AS-14697, M230, SAM001246883, SC-94573, AB0015125, AB2000448, LS-114934, EU-0100246, FT-0603147, C 6022, J10393, WLN: L C676 BYJ BU- DT6N DYTJ A1 &GH, SR-01000003077-2, SR-01000003077-4, SR-01000003077-9, Piperidine,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, 4-(5h-dibenzo [a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride, 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidine)-methylpiperidine hydrochloride, 1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaen-2-ylidene}piperidine hydrochloride, AC1LCW8O, AKOS024366257, MCULE-4137922083, ST50999681, 4-dibenzo[b,f][7]annulen-5-ylidene-1-methylpiperidine, chloride

ID: 2843

chemical graph of compound 2843



InChIKey: ZQKVPFKBNNAXCE-WFIJOQBCSA-L
SMILES: C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11957711
synonyms found at PubChem are:
Uridine-5'-diphosphate disodium salt, Uridine 5'-diphosphate sodium, UDP disodium salt, 27821-45-0, Uridine 5'-diphosphoric acid disodium salt, Uridine 5'-diphosphate disodium salt, URIDINE-5'-DIPHOSPHATE, DISODIUM SALT, Uridine 5'-diphosphate disodium salt hydrate, C9H12N2O12P2.2Na, 21931-53-3, UDP sodium salt, MFCD00006524, SCHEMBL1873401, Jsp005377, CHEMBL1457622, Uridine 5'-(Trihydrogen Pyrophosphate) Sodium Salt, MolPort-020-003-811, ZQKVPFKBNNAXCE-WFIJOQBCSA-L, HMS3263B12, Tox21_501205, HG1373, AKOS015893509, CCG-222509, CS-W011548, LP01205, NCGC00094452-01, NCGC00261890-01, AS-12237, B7278, EU-0101205, Z6031, M-1013, U 4125, Uridine 5a(2)-diphosphate disodium salt hydrate, I04-5936, Uridine 5-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate, UNII-CU84BH96WL, CU84BH96WL, Uridine 5'-(trihydrogen diphosphate), disodium salt, Disodium uridine 5'-diphosphate, EINECS 248-678-9, 909878-96-2, CTK8G3711, 975U448

ID: 2844

chemical graph of compound 2844



InChIKey: ZQPPMHVWECSIRJ-KTKRTIGZSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 445639
synonyms found at PubChem are:
oleic acid, 112-80-1, cis-9-Octadecenoic acid, cis-Oleic acid, Elaidoic acid, oleate, Glycon wo, Wecoline OO, Pamolyn 100, Glycon RO, (Z)-Octadec-9-enoic acid, Metaupon, Oelsauere, Vopcolene 27, Groco 5l, Groco 2, Groco 4, Groco 6, Tego-oleic 130, Emersol 211, Industrene 105, Industrene 205, Industrene 206, Pamolyn, Z-9-Octadecenoic acid, Oleinic acid, Emersol 210, Emersol 213, L'Acide oleique, cis-Octadec-9-enoic acid, Century cd fatty acid, Emersol 6321, Extraolein 90, Oleine 7503, 9-Octadecenoic acid (Z)-, Emersol 205, Emersol 233LL, Hy-phi 1055, Hy-phi 1088, Hy-phi 2066, Hy-phi 2088, Hy-phi 2102, Priolene 6906, White oleic acid, Wochem no. 320, Emersol 220 white oleic acid, Extra Oleic 80R, Extra Oleic 90, Extra Oleic 99, Extra Olein 80, Extra Olein 90R, Lunac O-CA, Lunac O-LL, Lunac O-P, neo-Fat 92-04, Priolene 6907, Priolene 6928, Priolene 6930, Priolene 6933, 9Z-Octadecenoic acid, Elainic acid, Emersol 6313NF, cis-Oleate, Elaic acid, delta9-cis-Oleic acid, 9-Octadecenoic acid (9Z)-, 9-Octadecenoic acid, (Z)-, 9-octadecenoic acid, (9Z)-Octadecenoic acid, FEMA Number 2815, Oleic acid, pure, D 100 (fatty acid), Emersol 221 low titer white oleic acid, K 52, Caswell No. 619, Oleic acid (natural), Wecoline OO (VAN), FEMA No. 2815, Oelsaeure, Acide oleique [French], HSDB 1240, l'Acide oleique [French], UNII-2UMI9U37CP, D 100, (9Z)-octadec-9-enoic acid, CCRIS 682, Oleic acid [NF], 9-octadecylenic acid, Emersol 233, NAA 35, 18:1Delta9cis, CHEBI:16196, cis-delta(sup 9)-Octadecenoic acid, NSC 9856, 9,10-Octadecenoic acid, EINECS 204-007-1, C18:1n-9, neo-Fat 90-04, .delta.9-cis-Oleic acid, 9-(Z)-octadecenoic acid, (Z)-9-Octadecanoic acid, EPA Pesticide Chemical Code 031702, 9-Octadecenoic acid, cis-, cis-.delta.9-Octadecenoate, (9Z)-9-Octadecenoic acid, BRN 1726542, 2UMI9U37CP, CHEMBL8659, AI3-01291, cis-.delta.9-Octadecenoic acid, cis-Delta(9)-octadecenoic acid, Red oil, NSC9856, ZQPPMHVWECSIRJ-KTKRTIGZSA-N, Oleic acid (NF), C18:1 n-9, Octadec-9-enoic acid, NCGC00091119-02, 18:1 n-9, C18:1, cis-9-octadecenoate, (9Z)- Octadecenoic acid, DSSTox_CID_5809, DSSTox_RID_77930, DSSTox_GSID_25809, (Z)-octadec-9-enoate, Acide oleique, cis-delta9-octadecenoic acid, CAS-112-80-1, SMR000326739, Sulfurized oleic acid, Sulphurized oleic acid, Oleic acid, sulfurized, Distoline, Oleinate, oleaic acid, Rapinic acid, 1gni, 1hms, 1vyf, 2lkk, Lunac OA, Edenor ATiO5, Edenor FTiO5, Industrene 104, Z-9-Octadecenoate, EINECS 270-164-8, Oleic acid, p.a., Emersol 213NF, Emersol 214NF, OLEICACID, Pamolyn 125, Priolene 6900, 9,10-Octadecenoate, 9-Octadecenoic acid (Z)-, sulfurized, Oleic acid (8CI), oleic acid extra pure, cis-Octadec-9-enoate, Pamolyn 100 FG, Pamolyn 100 FGK, 9-(Z)-octadecenoate, Emersol 7021, 9-Octadecenoic acid (9Z)-, sulfurized, (Z)-9-Octadecanoate, Emersol 6313 NF, Emersol 6333 NF, PubChem24077, Oleic acid-9,10-t, (9Z)-9-Octadecenoate, 9-cis-Octadecenoic acid, z-octadeca-9-enoic acid, AC1L9IBL, Oleic Acid-Water Soluble, D0A4EA, Epitope ID:187036, Oleic acid, natural, FCC, (9Z)octadec-9-enoic acid, Emersol 220 White Oleate, Oleic acid, technical grade, SCHEMBL1138, Delta9-cis-Octadecenoic acid, WLN: QV8U9-C, 4-02-00-01641 (Beilstein Handbook Reference), MLS001056779, MLS002153498, MLS002454427, 9-octadecenoic acid, (9Z)-, (9Z)-9-Octadecenoic acid #, GTPL1054, Oleic acid, analytical standard, DTXSID1025809, Oleic acid, >=93% (GC), Oleic acid, >=99% (GC), REGID_for_CID_445639, Oleic Acid CCyclodextrin Complex, 1g74, MolPort-001-788-274, s158, cis-| currency9-Octadecenoic acid, HMS2234O13, HMS3649H21, Oleic acid, technical grade, 90%, HY-N1446, NSC-9856, ZINC6845860, Tox21_111086, Tox21_201967, Tox21_303324, BDBM50150484, HSCI1_000362, LMFA01030002, LS-560, MFCD00064242, s4707, SBB058695, 9-Octadecenoic acid (9Z)- (9CI), cis-9-Octadecenoic-9,10-3H2 acid, Emersol 221 Low Titer White Oleate, AKOS017343225, cis-.delta.(sup 9)-Octadecenoic acid, RL00518, 9-Octadecenoic-9,10-t2 acid, (Z)-, NCGC00091119-01, NCGC00091119-03, NCGC00257233-01, NCGC00259516-01, 68412-07-7, AK187813, AN-22719, AS-16066, BP-24023, CC-33313, SC-19057, Oleic acid, SAJ first grade, >=70.0%, Oleic acid, Selectophore(TM), >=99.0%, CS-0016886, O0011, O0180, ST24031497, C00712, D02315, K-0971, Oleic acid, from suet, natural, >=60% (GC), AB00641912_08, 9-Octadecenoic-9,10-t2 acid, (9Z)- (9CI), Oleic acid, suitable for cell culture, BioReagent, SR-01000780573, SR-01000780573-6, F0001-0262, Oleic acid, certified reference material, TraceCERT(R), Oleic acid, European Pharmacopoeia (EP) Reference Standard, UNII-13FB83DEYU component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-44NH37HHP9 component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-5U9XZ261ER component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-7N137Q0QYJ component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-96GS7P39SN component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-9B22238JYI component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-B6G0Y5Z616 component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-HBA528N3PW component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-MO7HV04S9Y component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-ODL221H4AM component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-UDR641JW8W component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, UNII-V1PY73ZXPE component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, 459CE4C0-C836-4249-8E2D-69874B714E9C, UNII-79P21R4317 component ZQPPMHVWECSIRJ-KTKRTIGZSA-N, Oleic acid, United States Pharmacopeia (USP) Reference Standard, Oleic acid, meets analytical specification of Ph, Eur., 65.0-88.0% (GC), Oleic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, Oleic Acid-Water Soluble, powder, BioReagent, suitable for cell culture, 1190712-11-8, 1190965-71-9, 1380514-02-2, 17156-84-2, 56833-51-3, 8046-01-3, 949900-16-7, Oleic acid compound with (2R,3R,4S)-2-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol (1, Oleic acid, PharmaGrade, Manufactured under appropriate controls for use as raw material in pharma or biopharmaceutical production.

ID: 2845

chemical graph of compound 2845



InChIKey: ZRJBHWIHUMBLCN-SEQYCRGISA-N
SMILES: C/C=C\1/[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 907504
synonyms found at PubChem are:
(-)-huperzine A, 102518-79-6, Huperzine A, (-)-Selagine, (-)huperzine A, (-)-Huperzine A (HupA), (-)- HUPPERZINE A, SCHEMBL136369, MolPort-003-941-684, ZRJBHWIHUMBLCN-SEQYCRGISA-N, HUPERZINE A (naturally extracted), ZINC2094254, CH0011, MFCD01714949, s2251, (-)-Huperzine A, analytical standard, AKOS015895133, AKOS015951180, AKOS025312517, CS-1153, CPD000469231, HY-17387, Q437, SAM001246851, AB1008571, KB-333575, BRD-K45888792-001-01-0, (1R,9R)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,10-trien-5-one, (5R,9R,Z)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2-ol

ID: 2846

chemical graph of compound 2846



InChIKey: ZRSCGBGNKZDPOF-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C(CO2)CC3=CC(=C(C=C3)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4643334
synonyms found at PubChem are:
DEOXYSAPPANONE B TRIMETHYL ETHER, KBio2_001243, AC1NEJNT, Spectrum_000763, SpecPlus_000930, Spectrum2_000187, Spectrum3_000211, Spectrum4_001617, Spectrum5_000373, BSPBio_001821, KBioGR_001993, KBioSS_001243, SPECTRUM201331, DivK1c_007026, SPBio_000113, SCHEMBL4736096, CHEMBL1482446, KBio1_001970, KBio2_003811, KBio2_006379, KBio3_001321, CHEBI:110184, CCG-38395, SDCCGMLS-0066444.P001, NCGC00095504-01, NCGC00095504-02, SR-05000002588, SR-05000002588-1, BRD-A77164655-001-02-3, BRD-A77164655-001-03-1, 3-[(3,4-dimethoxyphenyl)methyl]-7-methoxy-2,3-dihydrochromen-4-one

ID: 2847

chemical graph of compound 2847



InChIKey: ZRVDANDJSTYELM-FXAWDEMLSA-N
SMILES: CC(C)C1=C(C=CC2=C1CC[C@@H]3[C@@]2(CCCC3(C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 92783
synonyms found at PubChem are:
Totarol, 511-15-9, (+)-Totarol, UNII-67NH2854WW, 14-Isopropylpodocarpa-8,11,13-trien-13-ol, CHEBI:69241, 67NH2854WW, (+)-8,11,13-totara-trien-13-ol, (4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, AC1L3OTS, AC1Q7AH2, MLS002695958, SCHEMBL285501, CHEMBL487602, DTXSID9047752, BCBcMAP01_000081, CTK8F1814, MolPort-003-936-051, 2-Phenanthrenol,4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, (4bS,8aS)-, BCP15142, ZINC1872131, BDBM50392993, AKOS025296157, API0004459, LMPR0104070001, 4b,5,6,7,8,8a,9,10-Octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-2-phenanthrenol, SMP1_000215, NCGC00385162-01, 2-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, (4bS,8aS)-, CC-35114, CJ-30698, SMR001562118, FT-0603433, V2342, (4bS,8aS)-1-isopropyl-4b,8,8-trimethyl-, 4b,5,6,7,8,8a,9,10-octahydrophenanthren-2-ol, C-18050, (4bS,8aS)-4b,8,8-trimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol, (4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol, 98%

ID: 2848

chemical graph of compound 2848



InChIKey: ZRWPUFFVAOMMNM-UHFFFAOYSA-N
SMILES: C1C=C2C(=CC(=O)O2)C(O1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4696
synonyms found at PubChem are:
patulin, Clavacin, Expansin, Clavatin, Claviform, Expansine, Patuline, Clairformin, Claviformin, 149-29-1, Gigantin, Leucopin, Tercinin, Mycoin, Mycoine C3, Mycoin C3, Penicidin, Mycosin, Penatin, Terinin, Mycoin C, 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one, Sch-351633, NSC 8120, NSC 32951, 4-Hydroxy-4H-furo(3,2-C)pyran-2(6H)-one, CCRIS 4940, (2,4-Dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid, 3,4-lactone, 4,6-Dihydro-4-hydroxy-2H-furo(3,2-c)pyran-2-one, HSDB 3522, NSC8120, NSC32951, EINECS 205-735-2, 4H-Furo(3,2-c)pyran-2(6H)-one, 4-hydroxy-, 4H-Furo[3,2-c]pyran-2(6H)-one, 4-hydroxy-, SCH 351633, (2,4-Dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid-3,4-lactone, BRN 0149675, CHEMBL294018, CHEBI:74926, 4-hydroxy-4,6-dihydrofuro[3,2-c]pyran-2-one, ZRWPUFFVAOMMNM-UHFFFAOYSA-N, 4H-Furo(3,3-c)pyran-2(6H)-one, 4-hydroxy-, Acetic acid, (2,4-dihydroxy-2H-pyran-3(6H)-ylidene)-, 3,4-lactone, 4,6-dihydro-4-hydroxy-2H-furo[3,2-c]pyran-2-one, (2, 3,4-lactone, 2,4-Dihydroxy-2H-pyran-delta-3(6H),alpha-acetic acid-3,4-lactone, 2H-Pyran-delta(sup 3(6H),alpha)-acetic acid, 2,4-dihydroxy-, 3,4-lactone, 4-Hydroxy-4,6-dihydrofuro[4,5-c]pyran-2-one, 4H-Furo[3, 4-hydroxy-, 4-hydroxy-4,6-dihydro-2H-furo[3,2-c]pyran-2-one, 2,.alpha.-acetic acid, 3,4-lactone, WLN: T56 BOV GO IU & TJ FQ, 748133-69-9, SR-05000002238, Clavicin, Clavitin, Expansion, 2H-Pyran-.delta.(sup 3(6H), 2,4-dihydroxy-, 3,4-lactone, Acetic acid,4-dihydroxy-2H-pyran-3(6H)-ylidene)-, 3,4-lactone, Gigantic acid?, Spectrum_000015, Antibiotic YS 1649, AC1L1IQY, Spectrum3_000796, Spectrum4_000753, Spectrum5_001659, Standard Solution Patulin, D0LB4A, PATULIN 13C3, Antibiotic Sch 351633, Patulin, reference material, Neuro_000008, SCHEMBL29056, BSPBio_002532, KBioGR_001106, KBioSS_000355, 5-18-03-00005 (Beilstein Handbook Reference), DivK1c_000438, SPECTRUM1503904, MEGxm0_000442, DTXSID2021101, ACon1_002106, HMS501F20, KBio1_000438, KBio2_000355, KBio2_002923, KBio2_005491, KBio3_001752, MolPort-003-665-945, NINDS_000438, ZX-AFC003098, HMS1923M19, Patulin, >=98.0% (HPLC), BCP29227, NSC-8120, BDBM50158841, CP0142, LS-868, MFCD00005858, NSC-32951, AKOS015904103, CCG-208451, FCH1114665, YS 1649, IDI1_000438, SMP1_000230, NCGC00095272-01, NCGC00095272-02, NCGC00095272-03, NCGC00095272-04, NCGC00095272-05, CC-33482, NCI60_041782, TR-006033, 4-Hydroxy-4H,6H-furo[3,2-c]pyran-2-one, FT-0631849, ST50824441, 4-Hydroxy-4H-Furo(3,3-c)pyran-2(6H)-one, C16748, 4-hydroxy-2H,4H,6H-furo[3,2-c]pyran-2-one, 4-hydroxy-6-hydro-4H-furano[3,2-c]pyran-2-one, C-30428, J-008576, SR-05000002238-2, SR-05000002238-3, I14-18325, 4-oC>>u-4H-ss>>[3,2-c]ssAa<<-2(6H)-I feminine, 2,4-Dihydroxy-2H-pyran-alpha -acetic acid, 3, 4-lactone, 2-Hydroxy-3,7-dioxabicyclo[4.3.0]nona-5,9-dien-8-one, 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one, 9CI, 8CI, 2H-Pyran-.delta.(sup 3(6H), 2,4-dihydroxy-,3,4-lactone, 2H-Pyran-alpha )-acetic acid, 2, 4-dihydroxy-,3,4-lactone, 2H-Pyran-alpha )-acetic acid, 2,4-dihydroxy-, 3,4-lactone, Patulin solution, 100 mug/mL in acetonitrile, analytical standard, Patulin solution, 100 mug/mL in chloroform, analytical standard, 2,4-Dihydroxy-2H-pyran-.delta.-3(6H),.alpha.-acetic acid, 3,4-lactone, 2H-Pyran-.delta.(3(6H),.alpha.)-acetic acid, 2,4-dihydroxy-,3,4-lactone, Patulin solution, certified reference material, 100 mug/mL in chloroform, ampule of 1 mL, 247172-18-5

ID: 2849

chemical graph of compound 2849



InChIKey: ZSBXGIUJOOQZMP-JLNYLFASSA-N
SMILES: C1C[C@@H]2[C@H]3CCCN4[C@H]3[C@@H](CCC4)CN2C(=O)C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 91466
synonyms found at PubChem are:
Matrine, 519-02-8, (+)-Matrine, Matridin-15-one, Matrinium, UNII-N390W430AC, Matrene, (+)-, NSC 146051, BRN 0085851, CHEBI:6700, N390W430AC, C15H24N2O, (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aS,13aR,13bR,13cS)-, alpha-Matrine, cis-Neomatrine, (+)-Matrine, 519-02-8, trans-Neomatrine, Matrine,(S), Matrine ((+)-Matrine), AC1L3M4P, Matridin-15-one (9CI), 5-24-02-00301 (Beilstein Handbook Reference), SCHEMBL177907, CHEMBL204860, CTK1H0283, DTXSID00274188, MolPort-002-517-366, BCP08193, HY-N0164, ZINC2083329, ANW-43480, CM0087, MFCD00210527, NSC146051, s2322, AKOS007930266, CCG-208589, CS-1601, KS-5203, NSC-146051, RL03912, RTR-031399, NCGC00346593-01, AK164135, AN-45507, LS-89363, O723, TR-031399, FT-0698746, M2120, N1836, 19M028, C10774, (41S,7aS,13aR,13bR)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, (7aS,13aR,13bS,13cS)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3,2,1-ij][1,6]naphthyridin-10-one

ID: 2850

chemical graph of compound 2850



InChIKey: ZSDSQXJSNMTJDA-UHFFFAOYSA-N
SMILES: CCCN(CCC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5569
synonyms found at PubChem are:
trifluralin, 1582-09-8, Treflan, Agreflan, Elancolan, Crisalin, Triflurex, Trifurex, Tristar, Nitran, Nitran K, 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline, Trifluraline, Crisalina, Digermin, Synfloran, Trefanocide, Treficon, Trikepin, Ipersan, Olitref, Super-Treflan, Agriflan 24, Treflam, Benzenamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-, Tri-4, Treflan EC, Su seguro carpidor, Trifluralina 600, Lilly 36,352, PREMERLIN, Treflanocide elancolan, Caswell No. 889, UNII-C8BX46QL7K, Trifluraline [ISO-French], Trifluralin, technical grade, Trilin 4EC, 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine, CCRIS 607, Trifluralin [ANSI:BSI:ISO], L-36352, 2,6-Dinitro-N,N-dipropyl-4-trifluoromethylaniline, Treflan (trifluralin), HSDB 1003, NCI-C00442, EINECS 216-428-8, EPA Pesticide Chemical Code 036101, alpha,alpha,alpha-Trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine, N,N-Dipropyl-4-trifluoromethyl-2,6-dinitroaniline, BRN 1893555, C8BX46QL7K, 4-(Trifluoromethyl)-2,6-dinitro-N,N-dipropylaniline, N,N-Di-n-propyl-2,6-dinitro-4-trifluoromethylaniline, AI3-28203, 4-(Di-n-propylamino)-3,5-dinitro-1-trifluoromethylbenzene, CHEBI:35027, ZSDSQXJSNMTJDA-UHFFFAOYSA-N, N,N-Dipropyl-2,6-dinitro-4-trifluoromethylaniline, 2,6-Dinitro-4-trifluormethyl-N,N-dipropylanilin [German], 2,6-Dinitro-6-trifluormethyl-N,N-dipropylanilin [German], N,N-Dipropyl-2,6-dinitro-4-trifluormethylanilin [German], 2,6-Dinitro-N,N-di-n-propyl-alpha,alpha,alpha-trifluoro-p-toluidine, DSSTox_CID_1395, p-Toluidine, .alpha.,.alpha.,.alpha.-trifluoro-2,6-dinitro-N,N-dipropyl-, DSSTox_RID_76136, DSSTox_GSID_21395, Trifluralin, analytical standard, 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)-benzamine, p-Toluidine, alpha,alpha,alpha-trifluoro-2,6-dinitro-N,N-dipropyl-, 75635-23-3, CAS-1582-09-8, elanocolan, trifuraline, Sinflouran, Brassix, Commence, Trifloran, Zeltoxone, Trilin, Treflan MTF, Treflan 5G, Agriphlan 24, Treflan 4EC, Agreflan 24, Treflan 10G, Trefl an 10G, Treflan TR-10, TRIFLURALIN EC, Trimaran (Salt/Mix), Spectrum_001839, SpecPlus_000440, TREFLAN(R), AC1Q2XPP, Spectrum2_001888, Spectrum3_000830, Spectrum4_000670, Spectrum5_001972, AC1L1KN2, 2,6-Dinitro-4-trifluormethyl-N,N-dipropylanilin, 2,6-Dinitro-6-trifluormethyl-N,N-dipropylanilin, BIDD:PXR0025, N,N-Dipropyl-2,6-dinitro-4-trifluormethylanilin, SCHEMBL21994, BSPBio_002359, KBioGR_001079, KBioSS_002344, SPECTRUM330038, MLS002454453, BIDD:ER0382, CHEMBL31970, DivK1c_006536, SPBio_001796, DTXSID4021395, CTK5E1805, KBio1_001480, KBio2_002341, KBio2_004909, KBio2_007477, KBio3_001859, MolPort-000-698-870, Benezeneamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-, NCI C00443, EBD43337, HY-B2050, ZINC3873953, Tox21_201352, Tox21_300918, CCG-39426, LS-906, Scotts Stop Weeds Before They Start, STK792949, AKOS005608916, CS-5200, KF10033, KS-5357, MCULE-3549367398, NCGC00091301-01, NCGC00091301-02, NCGC00091301-03, NCGC00091301-04, NCGC00091301-05, NCGC00091301-06, NCGC00091301-07, NCGC00091301-08, NCGC00254821-01, NCGC00258904-01, Trifluralin 10 microg/mL in Cyclohexane, 71281-30-6, AN-49490, I703, SMR000778097, ST046418, Trifluralin 10 microg/mL in Acetonitrile, FT-0603564, EN300-67184, C14343, K-4963, Trifluralin, PESTANAL(R), analytical standard, 582T098, A809905, 2,6-dinitro-N,N-dipropyl-4-trifluoromethyl-aniline, 4-DIPROPYLAMINO-3,5-DINITROBENZO-TRIFLUORIDE, I01-8048, J-009482, N,N-dipropyl-2,6-dini tro-4-trifluoromethylaniline, (2,6-Dinitro-4-trifluoromethyl-phenyl)-dipropyl-amine, [2,6-dinitro-4-(trifluoromethyl)phenyl]dipropylamine, 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline #, N,N-di-n-propyl-2,6-dinitro-4-(trifluoromethyl)aniline, 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine, 4-(Di-n-propylamino)-3,5-dinitro-1-(trifluoromethyl)benzene, A,A,A-TRIFLUORO-2,6-DINITRO-N,N-DIPROPYL-P-TOLUIDINE, Benezeneamine, 2,6-di nitro-N,N-dipropyl-4-(trifluoromethyl)-, Benzeneamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-, Trifluralin2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline, 2,6-dinitro-N,N-dipropyl-alpha,alph a,alpha-trifluoro-p-toluidine, 2,6-dinitro-N,N-dipropyl-alpha,alpha,alpha-trifluoro-p-toluidine, Benzenamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- (9CI), .alpha.,.alpha.,.alpha.-Trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine, 2,6-Dinitro-N,N-di-n-propyl-.alpha.,.alpha.,.alpha.-trifluoro-p-toluidine, Trifluralin solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 39300-53-3, 52627-52-8, 61373-95-3, trifluralin;2,6-dinitro-n,n-dipropyl-4-(trifluoromethyl)-benzamine; 4-(di-n-propylamino)-3,5-dinitro-1-trifluoromethylbenzene; alpha,alpha,alpha-trifluoro-2,6-dinitro-n,n-dipropyl-p-toluidine; agrefla

ID: 2851

chemical graph of compound 2851



InChIKey: ZSKVGTPCRGIANV-ZXFLCMHBSA-N
SMILES: C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 104838
synonyms found at PubChem are:
imipenem, Imipemide, N-Formimidoylthienamycin, 64221-86-9, Imipenem anhydrous, Tienamycin, Imipenemum, N-formimidoyl thienamycin, Imipenen, MK 0787, Imipenem, N-Formimidoyl thienamycin, (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure, UNII-Q20IM7HE75, Imipenem (INN), Primaxin, CHEBI:471744, CHEMBL148, Q20IM7HE75, (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, Imipenem [INN], Imipenemum [Latin], (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, DSSTox_CID_3143, DSSTox_RID_76888, DSSTox_GSID_23143, (5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, EINECS 264-734-5, MK-787, (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, CAS-64221-86-9, SR-05000000294, NCGC00016928-01, Primaxin (TN), (5R,6S)-3-[2-(aminomethyleneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-(2-methanimidamidoethylsulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-((1R)-1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R,6S)-, Prestwick_844, AC1L2XLB, Prestwick0_000519, Prestwick1_000519, Prestwick2_000519, Prestwick3_000519, D0H3TD, Epitope ID:120384, BSPBio_000477, BIDD:GT0686, SPBio_002398, BPBio1_000525, SCHEMBL1649260, SCHEMBL8781920, DTXSID2023143, ZSKVGTPCRGIANV-ZXFLCMHBSA-N, HMS1569H19, HMS2090A15, HMS2096H19, HMS3260H20, HMS3713H19, Pharmakon1600-01506001, 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5-alpha,6-alpha(R*)))-, 64221-86-9 (Parent), BCP13012, ZINC4097225, Tox21_110689, Tox21_500279, BDBM50049708, NSC717864, NSC759901, AKOS016010844, Tox21_110689_1, AN-9651, CCG-220519, CCG-221583, DB01598, LP00279, NSC-717864, NSC-759901, 64221-86-9 (ANHYDROUS), NCGC00167958-01, NCGC00167958-02, NCGC00167958-03, NCGC00167958-05, NCGC00260964-01, AJ-47996, AN-15734, BC209124, FT-0627191, C06665, D04515, X-2302, AB01563339_01, 847I667, SR-05000000294-2, SR-05000000294-5, (5R,6S)-3-((2-formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-3-(2-formimidamidoethylthio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, [5R-[5.alpha.,6.alpha.(R*)]]-6-(1-Hydroxyethyl)-3-[[2- [(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2- ene-2-carboxylic acid monohydrate, [5R-[5.alpha.,6.alpha.(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, 103730-39-8, 127644-14-8, 3-[(2-Aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methylester monohydrochloride compd. with 1-methyl-2-pyrrolidinone (1:1), 345631-68-7, 75902-88-4

ID: 2852

chemical graph of compound 2852



InChIKey: ZUFQODAHGAHPFQ-UHFFFAOYSA-N
SMILES: CC1=NC=C(C(=C1O)CO)CO.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6019
synonyms found at PubChem are:
PYRIDOXINE HYDROCHLORIDE, 58-56-0, Pyridoxine HCl, Pyridoxol hydrochloride, vitamin B6, Alestrol, Becilan, Benadon, Hexavibex, Hexermin, Hexobion, Pyridipca, Beesix, Pydox, Campoviton 6, Pyridoxine chloride, Aderoxin, Aderoxine, Bonasanit, Godabion, Hexabetalin, Paxadon, Pyridox, Pyridoxinium chloride, Rodex, Hexa-Betalin, Aderomine hydrochloride, Hexabione hydrochloride, Pyridoxin hydrochloride, Hexa-Betalin (R), Spondylonal, Bendectin, Adermine hydrochloride, Rodex (R), Pyridoxol, hydrochloride, Pyridoxine monohydrochloride, PN HCl, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride, Pyridoxine, hydrochloride, 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride, UNII-68Y4CF58BV, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride, Pyridoxinum hydrochloricum (Hungarian), Hexa-betalin (TN), CCRIS 1903, component of Alestrol, Pyridoxinum hydrochloricum, HSDB 1212, Tex Six T.R., 3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride, 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride, Vitamin B6-hydrochloride, EINECS 200-386-2, (5-hydroxy-6-methylpyridine-3,4-diyl)dimethanol hydrochloride, NSC 36225, Adermin hydrochloride, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride, AI3-19016, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride, 68Y4CF58BV, 3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride, CHEBI:30961, Pyridoxine hydrogen chloride, Hexermine, Nestrex, Vitaped, PYRIDOXINE HYDROCHLORIDE, U.S.P., Rodex TD, 4,5-Bis(hydroxymethyl)-3-hydroxy-2-methylpyridine hydrochloride, Cernevit-12, Pyridoxine (INN), Q-201647, 3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride, 4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride (1:1), Pyridoxine-HCl Microencapsulated, SMR000674613, AIDS006784, AIDS-006784, NSC36225, Clorhidrato de piridoxina, NCGC00164317-01, 58-56-0 (HCL), 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;hydrochloride, 4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, chloride, Vitamin V6, Vitamin-B6, vitamin B-6, Vitamin B6 HCl, Prestwick_925, Pyridoxine hydrochloride [USP:JAN], Pyridoxine hydrochloride [USAN:JAN], Vitamin V6 (TN), Vitamin-B6 hydrochloride, AC1L1LMI, I notEuEO B6 NIEaNI, D07MUN, DSSTox_CID_10780, DSSTox_RID_79601, DSSTox_GSID_40792, SCHEMBL42293, MLS001074329, MLS002153915, 65-23-6 (Parent), Pyridoxine Hydrochloride (B6), Pyridoxine hydrochloride, 98%, AC1Q3F63, CHEMBL1200756, DTXSID1040792, BIP0612, MolPort-002-137-856, ZUFQODAHGAHPFQ-UHFFFAOYSA-N, ZX-AFC000745, HMS1569N08, KS-00000H0O, Pyridoxine hydrochloride[USAN:JAN], Tox21_302476, GE7948, MFCD00012807, NSC-36225, s3113, 65-23-6 (FREE BASE), Pyridoxine hydrochloride (JP15/USP), Pyridoxine hydrochloride (JP17/USP), ssA paragraph signss (1/4) NIEaNI, AKOS015891679, API0003993, CCG-220623, CS-W020418, LS-2332, MCULE-3103603321, 2-methyl-4,5-dimethylol-pyridin-3-ol, 3, 5-hydroxy-6-methyl-, hydrochloride, NCGC00180946-01, NCGC00256911-01, AC-12024, AK175099, AN-23603, AS-11752, BC203894, Pyridoxin hydrochloride (Vitamin B6-HCl), SC-16202, ST007554, WLN: T6NJ B1 CQ D1Q E1Q &GH, Pyridoxine hydrochloride, >=98% (HPLC), AB0010673, KB-105573, Pyridoxine hydrochloride, p.a., 98-102%, B2017, FT-0631260, P0561, D02179, 91086-EP2281816A1, 91086-EP2305219A1, inverted question mark(1)AE currencyNxEO NIEaNI, Pyridoxine Hydrochloride (B6), analytical standard, Pyridoxine hydrochloride, plant cell culture tested, SR-05000001644-4, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydro, F0001-2400, Pyridoxine hydrochloride, SAJ special grade, >=98.0%, Pyridoxine hydrochloride, Vetec(TM) reagent grade, 98%, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol hydrochloride, Pyridoxine hydrochloride, meets USP testing specifications, Pyridoxine Hydrochloride 1.0 mg/ml in Methanol (as free base), Pyridoxine hydrochloride, certified reference material, TraceCERT(R), Pyridoxine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Pyridoxine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Pyridoxine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Pyridoxine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Pyridoxine HCl (Vitamin B6) solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Pyridoxine hydrochloride, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, Pyridoxine hydrochloride, PharmaGrade, EP, manufactured under appropriate GMP controls for pharma or biopharmaceutical production, AC1LAOEB, MolPort-000-729-069, SBB057400, AKOS025116942, 4,5-bis(hydroxymethyl)-2-methylpyridin-1-ium-3-ol chloride, Pyridoxine hydrochloride, 99% 25g, AKOS026749988, A831923, 4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol; hydron; chloride, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol; hydron; chloride, SCHEMBL8992241

ID: 2853

chemical graph of compound 2853



InChIKey: ZULBIBHDIQCNIS-HNCPQSOCSA-N
SMILES: C1CSC2=N[C@H](CN21)C3=CC=C(C=C3)Br.C(=O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2724023
synonyms found at PubChem are:
62284-79-1, (-)-p-Bromotetramisole oxalate, L-p-BROMOTETRAMISOLE OXALATE, (-)-4-Bromotetramisole oxalate, S(-)-p-Bromotetramisole oxalate, (-)-p-Bromotetramisole (oxalate), 6-Bromolevamisole oxalate salt, (-)-p-Bromolevamisole oxalate, L-(-)-p-Bromotetramisole oxalate, (-)-4-Bromotetramisole oxalate salt, (S)-(-)-4-Bromotetramisole oxalate, (S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate, (S)-(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate salt, (S)-(-)-4-Bromotetramisole Oxalate;(-)-4-bromotetramisole oxalate salt;()-p-Bromolevamisole oxalate, 6-Bromolevamisole oxalate, L(-)-p-bromotetramisole oxalate, C11H11BrN2S.C2H2O4, PubChem6166, R 30402 oxalate, EU-0100021, AC1MC43I, ()-p-Bromolevamisole oxalate, BMK1-H3, MLS000860040, CHEMBL1256792, CTK8G0647, (-)-p-Bromotetramisole(oxalate), MolPort-003-927-347, HMS2231M14, HMS3260E03, BCP16717, KS-00001DG1, Tox21_500021, (-)-p-Bromolevamisole oxalate 99%, (-)-p-Bromotetramisole oxalate salt, 2125AH, s7383, (-)-p-Bromolevamisole oxalate, 99%, AKOS030526170, CCG-221325, CS-5385, LP00021, NCGC00093544-01, NCGC00260706-01, BC003102, HY-19695, SMR000326898, MLS-0317970.P017, FT-0640818, ST50308584, SR-01000075599, SR-01000075599-1, S(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate, (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole; oxalic acid, (6S)-6-(4-bromophenyl)-2H,3H-2-imidazolino[2,1-b]1,3-thiazolidine, ethanedioic acid

ID: 2854

chemical graph of compound 2854



InChIKey: ZUXABONWMNSFBN-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2818
synonyms found at PubChem are:
clozapine, 5786-21-0, Leponex, Clozapin, Fazaclo, CLOZARIL, Clorazil, Iprox, Clozapinum, Asaleptin, Clozapina, Lepotex, Fazaclo ODT, HF-1854, Clozapinum [INN-Latin], Clozapina [INN-Spanish], W-801, clozapine(tautomer), Azaleptine, 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, UNII-J60AR2IKIC, Clozaril (TN), Clozapine [USAN:INN:BAN], HF 1854, CCRIS 9171, HSDB 6478, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, CHEMBL42, EINECS 227-313-7, HF1854, J60AR2IKIC, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, BRN 0764984, Clozapine (JAN/USP/INN), 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, C18H19ClN4, MLS000028472, CHEBI:3766, LX 100-129, LEX-123, QZUDBNBUXVUHMW-UHFFFAOYSA-N, 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, KS-1166, NCGC00015254-12, CPD000058365, SMR000058365, CAS-5786-21-0, 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b,e)(1,4)diazepine, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine, DSSTox_CID_2855, C 6305, DSSTox_RID_76759, DSSTox_GSID_22855, W-105432, Versacloz, 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine, 8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, 1333667-72-3, 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene, SR-01000000096, Azaleptin, Klozapol, Clozapine, solid, Clozapine [USAN:USP:INN:BAN], Denzapine (TN), Klozapol (TN), Prestwick_693, Clopine (TN), Fazaclo (TN), Froidir (TN), Leponex (TN), Zaponex (TN), Clozapine (Clozaril), Spectrum_000139, Tocris-0444, Opera_ID_482, AC1L1EJE, AC1Q3OPZ, AC1Q3ZWP, Prestwick0_000350, Prestwick1_000350, Spectrum2_000919, Spectrum3_001828, Spectrum4_000898, Lopac-C-6305, D0Z1RV, GTPL38, SCHEMBL8397, REGID_for_CID_2818, SCHEMBL33323, KBioGR_000310, KBioGR_001336, KBioSS_000310, KBioSS_000599, MLS001077282, DivK1c_000343, SPECTRUM1500685, SPBio_000798, SPBio_002340, DTXSID5022855, BDBM22869, CHEBI:92657, CTK6I2968, HMS501B05, KBio1_000343, KBio2_000310, KBio2_000599, KBio2_002878, KBio2_003167, KBio2_005446, KBio2_005735, KBio3_000619, KBio3_000620, KBio3_002979, AOB5635, MolPort-001-728-041, MolPort-006-167-528, NINDS_000343, Bio1_000436, Bio1_000925, Bio1_001414, Bio2_000310, Bio2_000790, HMS1361P12, HMS1569E21, HMS1791P12, HMS1921C16, HMS1989P12, HMS2089L13, HMS2092I16, HMS2096E21, HMS2235E19, HMS3259J17, HMS3260H14, HMS3266A10, HMS3371H05, HMS3402P12, HMS3657E15, HMS3713E21, Pharmakon1600-01500685, BCP25196, ZINC3872123, Tox21_110113, Tox21_500276, ANW-42470, BDBM50001884, BG0154, CC0176, CCG-39881, GP7633, MFCD00153785, NSC757429, s2459, ZINC19796155, Clozapine 1.0 mg/ml in Acetonitrile, AKOS005064444, AKOS026749900, Tox21_110113_1, CS-0644, DB00363, LP00276, MCULE-3665900006, NC00667, NSC-757429, NCGC00015254-01, NCGC00015254-02, NCGC00015254-03, NCGC00015254-04, NCGC00015254-05, NCGC00015254-06, NCGC00015254-07, NCGC00015254-08, NCGC00015254-09, NCGC00015254-10, NCGC00015254-11, NCGC00015254-13, NCGC00015254-14, NCGC00015254-15, NCGC00015254-16, NCGC00015254-17, NCGC00015254-18, NCGC00015254-20, NCGC00022902-02, NCGC00022902-04, NCGC00022902-05, NCGC00022902-06, NCGC00022902-07, NCGC00022902-08, NCGC00022902-09, NCGC00022902-10, NCGC00022902-11, NCGC00022902-12, NCGC00022902-13, NCGC00188978-01, NCGC00260961-01, AN-16004, BC204168, H482, HY-14539, LS-60881, SAM002548976, SAM002589962, SC-12183, SC-26976, SBI-0050264.P004, AB0013069, AB1009321, TC-063560, D-107, EU-0100276, FT-0082373, FT-0600382, EN300-52510, C06924, D00283, W-2845, AB00052158-13, AB00052158-14, AB00052158_15, AB00052158_16, 786C210, C-36335, Clozapine, drug standard, 1.0 mg/mL in methanol, L000195, L013417, I06-0047, SR-01000000096-2, SR-01000000096-4, SR-01000000096-5, SR-01000000096-8, BRD-K37289225-001-09-1, BRD-K37289225-001-23-2, Clozapine, British Pharmacopoeia (BP) Reference Standard, Z1245633277, Clozapine, European Pharmacopoeia (EP) Reference Standard, Clozapine, United States Pharmacopeia (USP) Reference Standard, 8-Chloro-11-(4-methylpiperazino)-5H-dibenzo[b,e][1,4]diazepine, (E)-8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, 3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methylpiperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine, 3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester, 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine), 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine ), 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine), 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine), Clozapine for peak identification, European Pharmacopoeia (EP) Reference Standard, Clozapine Resolution Mixture, United States Pharmacopeia (USP) Reference Standard, CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE, 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0(3),]pentadeca-1,3,5,7,10,12,14-heptaene, 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,9,12,14-heptaene

ID: 2855

chemical graph of compound 2855



InChIKey: ZUXNZUWOTSUBMN-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=NN=C2NN.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 9351
synonyms found at PubChem are:
HYDRALAZINE HYDROCHLORIDE, 304-20-1, 1-Hydrazinophthalazine hydrochloride, Apresoline, 1-Hydrazinylphthalazine hydrochloride, HYDRALAZINE HCL, Aiselazine, Hydralazine chloride, Hyperazin, Hyperex, Lopress, Slow-Apresolin, Dralzine, Hydralazine monohydrochloride, Apresoline hydrochloride, Hydrallazine hydrochloride, Hydralazine (hydrochloride), 1-Hydrazinophthalazine monohydrochloride, 1(2H)-Phthalazinone, hydrazone, monohydrochloride, CHEBI:31672, 1(2H)-Phthalazinone, hydrazone, hydrochloride, 1-hydrazinyl-Phthalazine hydrochloride, phthalazin-1-ylhydrazine hydrochloride, Apresoline (TN), DSSTox_CID_24645, DSSTox_RID_80373, DSSTox_GSID_44645, SR-01000075903, NCGC00015501-02, CAS-304-20-1, Hydralazine hydrochloride [JAN], Prestwick_610, Hydralazinhydrochlorid, ACMC-209hfr, AC1Q3COW, AC1Q3DGV, 1-hydrazinophthalazine HCL, C8H8N4.HCl, AC1L1SV4, SCHEMBL36271, Phthalazine, monohydrochloride, Hydralazine mono-Hydrochloride, KSC911I1L, ARONIS27196, SPECTRUM1500334, CHEMBL542541, Phthalazinone, monohydrochloride, DTXSID1044645, CTK3E4473, CTK8B1415, KS-00000XOB, AOB5342, BPI-103, MolPort-003-666-202, MolPort-003-941-613, mono-HYDRAZINOPHTHALAZINE HCl, ZUXNZUWOTSUBMN-UHFFFAOYSA-N, HMS1568B19, HMS1920D17, Pharmakon1600-01500334, 1-Hydrazinylphthalazinehydrochloride, HY-B0464, KS-000048OG, NSC89394, WLN: T66 CNNJ BMZ & GH, 1(2H)-Phthalazinone, hydrochloride, Tox21_110163, Tox21_302496, Tox21_500593, ANW-26869, CCG-40185, NSC-89394, NSC757058, s2562, SBB000358, AKOS008968535, AKOS025116605, AKOS028109609, Hydralazine hydrochloride (JP17/USP), Tox21_110163_1, 1(2H)-Phthalazinone, monohydrochloride, AN-1061, CS-2578, LP00593, MCULE-9301781478, NE41773, NSC-757058, RTR-013075, Phthalazinone hydrazone monohydrochloride, NCGC00015501-09, NCGC00093972-01, NCGC00093972-02, NCGC00093972-03, NCGC00093972-04, NCGC00256719-01, NCGC00261278-01, AC-18050, SC-16076, 1(2H)-Phthalazinone hydrazone hydrochloride, AB0062919, AB2000658, LS-109173, TR-013075, EU-0100593, FT-0669283, ST50825409, EN300-03637, D01302, H 1753, (1Z)-1-hydrazinylidene-2H-phthalazine hydrochloride, Q-201208, SR-01000075903-1, SR-01000075903-5, I14-85667, Z57980178, 81411-23-6, SCHEMBL36272, AKOS023093312, AKOS026750157

ID: 2856

chemical graph of compound 2856



InChIKey: ZUYKJZQOPXDNOK-UHFFFAOYSA-N
SMILES: CCNC1(CCCCC1=O)C2=CC=CS2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 26534
synonyms found at PubChem are:
TILETAMINE HYDROCHLORIDE, 14176-50-2, Tiletamine HCl, Tiletamin hydrochloride, Tiletamine (hydrochloride), Tiletamine monohydrochloride, CI-634, CN-54521-2, CL 399, 2-(Ethylamino)-2-(2-thienyl)cyclohexanone hydrochloride, Cyclohexanone, 2-(ethylamino)-2-(2-thienyl)-, hydrochloride, NSC 167740, CI 634, 2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one;hydrochloride, 2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one hydrochloride, Tiletamine hydrochloride [USAN:USP], NCGC00017004-01, AC1L1BC3, DSSTox_CID_25539, DSSTox_RID_80941, DSSTox_GSID_45539, SCHEMBL258460, Tiletamine hydrochloride (USP), CHEMBL2105342, DTXSID6045539, MolPort-028-720-449, HMS1571M05, Pharmakon1600-01503879, 14176-49-9 (Parent), HY-B0995, KS-00000TT5, Tox21_110731, CL-399, NSC167740, NSC760368, AKOS015914250, CCG-213233, CS-4489, NSC-167740, NSC-760368, AC-28315, KB-61734, TILETAMINE HYDROCHLORIDE (200 MG), CAS-14176-50-2, FT-0675235, D06146, 2-(Ethylamino)-2-(2-thienyl)cyclohexanone HCl, SR-01000872642, SR-01000872642-1, I14-44707, Cyclohexanone, 2-(ethylamino)-2-(2-thienyl)-, hydrochloride (8CI)(9CI), AKOS026749834

ID: 2857

chemical graph of compound 2857



InChIKey: ZVOIMYHOERDLNX-UVTDQMKNSA-N
SMILES: C1(=CC=CC=N1)/C(/[HH0])=N\NC1=CC=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 6090970
synonyms found at PubChem are:
(Z)-2-pyridine-carbaldehyde phenylhydrazone, 30915-37-8, AC1O198X, Picolinaldehyde phenyl hydrazone, ZINC5279218, N-[(Z)-pyridin-2-ylmethylideneamino]aniline, Pyridine-2-carbaldehyde (E)-phenyl hydrazone

ID: 2858

chemical graph of compound 2858



InChIKey: ZWAOHEXOSAUJHY-ZIYNGMLESA-N
SMILES: C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 18343
synonyms found at PubChem are:
doxifluridine, 5'-Deoxy-5-fluorouridine, 3094-09-5, 5-fluoro-5'-deoxyuridine, Furtulon, 5'-Dfur, Uridine, 5'-deoxy-5-fluoro-, Flutron, Doxifluridina, Doxifluridinum, 5'-Doxifluridine, Furtulon (TN), Uridine-5'-deoxy-5-fluoro-, 5'dFUrd, Ro 21-9738, Doxifluridine [INN:JAN], 5-DFUR, UNII-V1JK16Y2JP, Ro 219738, Doxifluridinum [INN-Latin], CHEMBL1130, V1JK16Y2JP, Doxifluridina [INN-Spanish], CHEBI:31521, 1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil, EINECS 221-440-1, NCGC00093926-03, Doxifluridine (5-Fluoro-5'-deoxyuridine), DSSTox_CID_2967, 5'FDUR, DSSTox_RID_76809, DSSTox_GSID_22967, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione, doxyfluridine, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione, 5'-dFUrd, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-dione, SMR000326811, CAS-3094-09-5, SR-01000075886, 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione (5'-Deoxy-5-fluorouridine), 38817-29-7, (+)-Doxifluridine, PubChem21074, AC1L2BUF, 5-Deoxy-5-fluorouridine, 5-Fluoro-5;-deoxyuridine, D03KXY, AC1Q29PS, SCHEMBL8094, Doxifluridine (JP17/INN), Lopac0_000537, KSC492G6N, MLS001332579, MLS001332580, MLS002172440, MLS002207077, URI004, DTXSID2022967, CTK3J2366, KS-00000EUP, MolPort-003-936-171, ZWAOHEXOSAUJHY-ZIYNGMLESA-N, HMS2090C22, HMS2231I05, HMS3261L15, ACN-S003358, HY-B0021, ZINC1319177, ZX-AP001976, Tox21_111231, Tox21_500537, ANW-13803, BDBM50132295, CD-197, MFCD00866530, PC5775, s2045, AKOS015852921, AKOS015896821, Tox21_111231_1, API0015889, CCG-204627, CS-1270, DB12947, Doxifluridine/5-Fluoro-5'-deoxyuridine, KS-5065, LP00537, NCGC00093926-01, NCGC00093926-02, NCGC00093926-05, NCGC00261222-01, Ro-21-9738, AK163078, CJ-04859, KB-50427, SRI-11552-08, SRI-11552_09, SY017052, ZB016270, 5''-Deoxy-5-Fluorouridine (5''-Dfur), LS-160821, EU-0100537, C12739, D01309, F 8791, W-5145, 15185-EP2272827A1, 15185-EP2275420A1, 15185-EP2295055A2, 15185-EP2295416A2, 15185-EP2295426A1, 15185-EP2295427A1, 15185-EP2298748A2, 15185-EP2298764A1, 15185-EP2298765A1, 15185-EP2298768A1, 15185-EP2298778A1, 15185-EP2305642A2, 15185-EP2311453A1, 15185-EP2311808A1, 15185-EP2311829A1, 15185-EP2316832A1, 15185-EP2316833A1, 094F095, A820661, SR-01000075886-1, SR-01000075886-5, (+)-1-(beta-D-5'-Deoxyribofuranosyl)-5-fluorouracil, 5'-DFUR (5'-Deoxy-5-fluorouridine, Doxifluridine), BRD-K58262659-001-09-7, Capecitabine impurity B, European Pharmacopoeia (EP) Reference Standard, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-2-oxolanyl]-5-fluoropyrimidine-2,4-dione, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-3H-pyrimidine-2,4-dione, 5-fluoranyl-1-[(2R,3R,4S,5R)-5-methyl-3,4-bis(oxidanyl)oxolan-2-yl]pyrimidine-2,4-dione, Capecitabine Related Compound B, United States Pharmacopeia (USP) Reference Standard, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione, 1-((2R,5R)-3,4-Dihydroxy-5-methyl-tetrahydro-furan-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione, 1-((4S,2R,3R,5R)-3,4-Dihydroxy-5-methyloxolan-2-yl)-5-fluoro-1,3-dihydropyrimidine-2,4-dione, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

ID: 2859

chemical graph of compound 2859



InChIKey: ZWBRYKKWRCXNTF-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=NN(C(=O)C2)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 5223467
synonyms found at PubChem are:
AC1NQJZU, AC1Q40CG, 2-methyl-5-(4-methylphenyl)-4H-pyrazol-3-one, SCHEMBL8619935, CTK8H4104, ZINC5682742, AKOS006276624, 2-METHYL-5-P-TOLYL-2,4-DIHYDRO-PYRAZOL-3-ONE, 1-methyl-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-5-one

ID: 2860

chemical graph of compound 2860



InChIKey: ZWIBGKZDAWNIFC-UHFFFAOYSA-N
SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O

biological descriptors:

CFTR relevance: cross-links WT and ΔF508 CFTR

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"W Wang" "KL Kirk" "R Narlawar" "B Schmidt" "K Bernard"


CID is 100658
synonyms found at PubChem are:
Disuccinimidyl suberate, 68528-80-3, bis(2,5-dioxopyrrolidin-1-yl) octanedioate, Suberic acid bis(N-hydroxysuccinimide ester), 68526-60-3, ZWIBGKZDAWNIFC-UHFFFAOYSA-N, 2,5-Pyrrolidinedione, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis-, Nhs-SA, Disuccinimidylsuberate, DSIS, N-Hydroxysuccinimide suberic acid ester, DSS Crosslinker, 2,5-Pyrrolidinedione, 1,1'-((1,8-dioxo-1,8-octanediyl)bis(oxy))bis-, Suberic acid bis(N-succinimidyl) ester, Disuccinimidyl octanedioate, ACMC-1B3E4, Di(N-succinimidyl) Suberate, SCHEMBL37833, BICL100, (DSS);Disuccinimidyl suberate, Disuccinimidyl suberate (DSS), AC1L2P76, Di(N-succinimidyl) Octanedioate, DSS (Chemical Shape Indicator), CTK5C8144, MolPort-003-959-513, ZX-AFC000038, KS-000002IF, 1,1'-((1,8-Dioxo-1,8-octanediyl)bis(oxy))bis-2,5-pyrrolidinedione, ANW-43415, KM1211, NSC340008, ZINC64857732, AKOS015915589, Suberic Acid Di(N-succinimidyl) Ester, GS-6316, NSC-340008, AK117747, AN-38041, BP-22656, KB-76674, SC-98072, Octanedioic Acid Di(N-succinimidyl) Ester, DB-055162, TR-037485, D3895, FT-0625348, FT-0641189, X3599, 528D803, I14-53916, 2, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis-, 1,8-Bis(2,5-dioxo-1-pyrrolidinyl)ester octanedioic acid, Octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl) ester, Suberic acid bis(N-hydroxysuccinimide ester), >=95%, powder, Amides, rice bran-oil,N-[2-[(2-hydroxyethyl)amino]ethyl], acetates (salts)

ID: 2861

chemical graph of compound 2861



InChIKey: ZWJINEZUASEZBH-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4386
synonyms found at PubChem are:
N-phenylanthranilic acid, 91-40-7, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Fenamic acid, Diphenylamine-2-carboxylic acid, Phenylanthranilic acid, Benzoic acid, 2-(phenylamino)-, 2-Carboxydiphenylamine, o-Anilinobenzoic acid, N-Phenyl-2-aminobenzoic acid, N-Phenyl-o-aminobenzoic acid, Anthranilic acid, N-phenyl-, 2-Phenylamino-benzoic acid, UNII-952VN06WBB, NSC 215211, EINECS 202-066-8, BRN 1456607, CHEMBL23832, AI3-08880, 952VN06WBB, 2,2&prime;-Iminodibenzoic Acid, CHEBI:34756, ZWJINEZUASEZBH-UHFFFAOYSA-N, IN1488, diphenylamine carboxylate, SR-01000075342, diphenylamine-2-carboxylate, N-Phenylanthranilic, DPC cpd, 2-anilino-benzoic acid, ACMC-209rbb, ortho-anilinobenzoic acid, n-phenyl anthranilic acid, N-phenyl-anthranilic acid, D03APP, AC1L1I1S, AC1Q5UU1, AC1Q72GC, AC1Q72GD, Lopac-144509, o-(Phenylamino)benzoic acid, CBiol_001836, Lopac0_000011, Oprea1_414882, Oprea1_622264, SCHEMBL25828, BSPBio_001421, CBDivE_001949, KBioGR_000141, KBioGR_002302, KBioSS_000141, KBioSS_002304, KSC494E8T, MLS002153472, BIDD:GT0820, SPECTRUM1505156, ARONIS004022, GTPL4182, N-Phenylanthranilic acid, 98%, DTXSID6059025, N-phenyl-ortho-aminobenzoic acid, BCBcMAP01_000076, CTK3J4289, Diphenylaminecarboxylic acid-(2), KBio2_000141, KBio2_002302, KBio2_002709, KBio2_004870, KBio2_005277, KBio2_007438, KBio3_000281, KBio3_000282, KBio3_002782, KS-00000GUN, KS-00003WVW, ZWJINEZUASEZBH-UHFFFAOYSA-, NSC4273, cMAP_000012, MolPort-000-927-722, Bio1_000122, Bio1_000611, Bio1_001100, Bio2_000141, Bio2_000621, HMS1361H03, HMS1791H03, HMS1989H03, HMS2232G15, HMS3260C03, HMS3373F04, HMS3402H03, ZINC154642, NSC-4273, Tox21_500011, ANW-39669, BBL008122, BDBM50337278, HTS027688, MFCD00002421, NSC215211, SBB012416, STK089446, Diphenylamine-2-carboxylic acid; DPC, AKOS000118791, CCG-204107, LP00011, MCULE-6051331548, NSC-215211, RP26754, RTR-028727, IDI1_033891, MLS-0412242, NCGC00014989-01, NCGC00014989-02, NCGC00014989-03, NCGC00014989-04, NCGC00014989-05, NCGC00014989-06, NCGC00014989-07, NCGC00014989-08, NCGC00093536-01, NCGC00093536-02, NCGC00093536-03, NCGC00093536-04, NCGC00093536-05, NCGC00093536-06, NCGC00260696-01, AJ-13327, AN-24211, DS-14719, KB-79548, LS-20563, SMR001230825, ST067120, MLS-0412242.P016, AB1003506, DB-057256, TR-028727, BB 0255314, D0873, EU-0100011, FT-0631438, ST24027651, T8281, C13697, 002P421, AE-641/02494034, N-Phenylanthranilic acid, technical, >=95% (T), SR-01000075342-1, SR-01000075342-2, W-100309, BRD-K80863915-001-02-9, BRD-K80863915-001-05-2, F3145-3322, 2-(Phenylamino)benzoic acid; Diphenylamine-2-carboxylic acid; DPC, InChI=1/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)

ID: 2862

chemical graph of compound 2862



InChIKey: ZXHLDNILIVGKPC-WOERNGHISA-N
SMILES: C[C@@]12CC[C@@H]3[C@]4(C=CC(=O)C([C@@H]4C=C[C@]3([C@@]15[C@H](O5)C(=O)O[C@H]2C6=COC=C6)C)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 52897276
synonyms found at PubChem are:
CHEMBL3138690, 7-Desacetoxy-6,7-dehydrogedunin, BDBM50155930

ID: 2863

chemical graph of compound 2863



InChIKey: ZXNRTKGTQJPIJK-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(=O)N2CCCC2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2196
synonyms found at PubChem are:
aniracetam, 72432-10-1, Draganon, Sarpul, Ampamet, 1-(4-Methoxybenzoyl)-2-pyrrolidinone, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Ro 13-5057, 1-p-Anisoyl-2-pyrrolidinone, Memodrin, Aniracetamun [INN-Latin], Aniracetam [USAN:INN:JAN], UNII-5L16LKN964, Ro 135057, BRN 4807205, 1-p-anisoylpyrrolidin-2-one, Ro-13-5057, 2-Pyrrolidinone, 1-(4-methoxybenzoyl)-, CHEMBL36994, MLS000079240, CHEBI:47943, 1-(p-Methoxybenzoyl)-2-pyrrolidinon [German], ZXNRTKGTQJPIJK-UHFFFAOYSA-N, 5L16LKN964, 1-(4-Methoxybenzoyl)-2-pyrrolidone, P-METHOXYBENZOYL-2-PIRROLIDONE, NCGC00015116-10, 1-(4-Methoxy-benzoyl)-pyrrolidin-2-one, SMR000038438, DSSTox_CID_25128, DSSTox_RID_80691, DSSTox_GSID_45128, Aniracetamun, CAS-72432-10-1, SR-01000003147, 1-anisoyl-2-pyrrolidinone, Reset, Aniracetam/, Aniracetam ,(S), 1-(p-Methoxybenzoyl)-2-pyrrolidinon, Draganon;Sarpul;Ampamet, Spectrum_001342, Tocris-0867, Aniracetam, >=98%, Opera_ID_294, Spectrum3_001553, Spectrum4_000761, Spectrum5_001609, Lopac-A-9950, Biomol-NT_000222, D02DPU, Lopac0_000115, SCHEMBL70998, BSPBio_003026, KBioGR_001142, KBioSS_001822, MLS000028591, MLS001201800, Aniracetam (JAN/USAN/INN), DivK1c_000403, SPECTRUM1503078, AC1L1D50, BPBio1_001316, GTPL4133, DTXSID5045128, CTK7A1943, HMS501E05, KBio1_000403, KBio2_001822, KBio2_004390, KBio2_006958, KBio3_002526, ZINC15951, AOB5256, MolPort-002-348-163, NINDS_000403, BCPP000399, HMS2089O17, HMS2094K07, HMS2234E11, HMS3260G12, HMS3266L08, HMS3657G11, HMS3713N20, Pharmakon1600-01503078, BCP02091, EBD34297, Tox21_110086, Tox21_500115, ABP000598, BN0777, KM1483, MFCD00153767, NSC758223, s1281, 1-(4-methoxybenzoyl)-2-pyrrolidinon, 1-(p-methoxybenzoyl)-2-pyrrolidinone, AKOS005066313, Tox21_110086_1, AB04115, ACN-048215, API0001505, BCP9000303, CCG-204210, CS-1793, DB04599, KS-5313, LP00115, NSC-758223, Ro-135057, 1-(4-ANISOYL)PYRROLIDIN-2-ONE, 2-Pyrrolidinone,1-(4-methoxybenzoyl)-, IDI1_000403, P-METHOXYBENZOYL-2-PYRROLIDINONE, NCGC00015116-01, NCGC00015116-02, NCGC00015116-03, NCGC00015116-04, NCGC00015116-05, NCGC00015116-06, NCGC00015116-07, NCGC00015116-08, NCGC00015116-09, NCGC00015116-11, NCGC00015116-12, NCGC00015116-13, NCGC00021402-02, NCGC00021402-05, NCGC00021402-06, NCGC00021402-07, NCGC00021402-08, NCGC00260800-01, Ro-13-3057, 1-(4-Methoxybenzoyl)-2-pyrrolidinone #, AC-15651, AN-16891, BC209377, HY-10932, K231, KB-47407, SC-27439, SBI-0050103.P004, AB0008034, AB2000026, LS-138873, TL8005061, 1-(4-methoxyphenyl)carbonylpyrrolidin-2-one, Draganon, Sarpul, Ampamet, 72432-10-1, EU-0100115, FT-0649064, 1-[(4-methoxyphenyl)carbonyl]pyrrolidin-2-one, 2-PYRROLIDINONE, 1-(4-METHOXYBENZOYL), A 9950, C13355, D01883, 1-[(4-methoxyphenyl)-oxomethyl]-2-pyrrolidinone, AB00053303-14, AB00053303_15, AB00053303_16, ANIRACETAM, 1-P-ANISOYL-2-PYRROLIDINONE, 432A101, A837527, C-58416, I06-2190, SR-01000003147-2, SR-01000003147-4, SR-01000003147-6, SR-01000003147-8, BRD-K88611939-001-02-6, BRD-K88611939-001-13-3

ID: 2864

chemical graph of compound 2864



InChIKey: ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC(=O)O2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 323
synonyms found at PubChem are:
coumarin, 2H-Chromen-2-one, 91-64-5, 2H-1-Benzopyran-2-one, cumarin, 1,2-Benzopyrone, Rattex, Tonka bean camphor, Coumarinic anhydride, chromen-2-one, Coumarine, Benzo-alpha-pyrone, cis-o-Coumarinic acid lactone, o-Hydroxycinnamic acid lactone, o-Hydroxycinnamic lactone, 2-Oxo-1,2-benzopyran, Coumarinic lactone, Kumarin, Benzo-a-pyrone, Kumarin [Czech], 2H-1-Benzopyran, 2-oxo-, 5,6-Benzo-2-pyrone, 5,6-Benzo-alpha-pyrone, 2H-Benzo(b)pyran-2-one, 2H-Benzo[b]pyran-2-one, Caswell No. 259C, o-Coumaric acid lactone, o-Hydroxyzimtsaure-lacton, NCI C07103, cis-o-Coumaric acid anhydride, benzopyranone, Benzopyrone, o-Hydroxyzimtsaure-lacton [German], UNII-A4VZ22K1WT, Benzopyran-2-one, NSC 8774, 2-Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone, CCRIS 181, EPA Pesticide Chemical Code 127301, BRN 0383644, C9H6O2, 1-Benzopyran-2-one, Benzo-.alpha.-pyrone, Cinnamic acid, o-hydroxy-, delta-lactone, CHEBI:28794, 2H-Benzopyran-2-one, AI3-00753, HSDB 1623, o-hydroxycinnamic acid delta-lactone, 2-oxo-2H-1-benzopyran, EINECS 202-086-7, 3-(2-Hydroxyphenyl)-2-propenoic delta-lactone, A4VZ22K1WT, CHEMBL6466, 2-Propenoic acid, 3-(2-hydroxyphenyl)-delta-lactone, MLS000028741, 103802-83-1, NSC8774, ZYGHJZDHTFUPRJ-UHFFFAOYSA-N, NCGC00091502-01, Coumarin, >=98%, SMR000059040, ST023509, DSSTox_CID_348, DSSTox_RID_75529, DSSTox_GSID_20348, 2-Propenoic acid, 3-(2-hydroxyphenyl)-, d-lactone, CAS-91-64-5, Coumarin [NF], COU, Coumarin [NF X], SR-01000721887, chromenone, chromen-one, d-lactone, 2-chromenone, coumarinac lactone, Benzo-2-pyrone, benzopyrylium olate, Coumarin (DCF), 1, 2-Benzopyrone, Venalot mono (TN), CUMARINA, Coumarinic acid lactone, PubChem21620, Spectrum_001336, ACMC-20aj0i, Opera_ID_268, Coumarinic acid lactone, 2H-Chromen-2-one #, 3-(2-hydroxyphenyl)-, 2H-1-benzopyran-2-on, AC1Q6HKG, Spectrum2_000303, Spectrum3_001772, Spectrum4_001818, Spectrum5_000555, 2-oxo-1,2-benzopy ran, bmse000077, Epitope ID:114082, 1,2-Benzopyrone, Cumarin, EC 202-086-7, AC1L18ZG, AC1Q6CR1, cis-O-coumaric acid lactone, SCHEMBL6252, WLN: T66 BOVJ, BSPBio_003263, Coumarin, 98% 250g, KBioGR_002460, KBioSS_001816, 5-17-10-00143 (Beilstein Handbook Reference), MLS001148422, MLS002454395, {2H-Benzo[b]pyran-2-one}, ARONIS24593, BIDD:ER0667, SPECTRUM1400208, SPBio_000266, Cinnamic acid, .delta.-lactone, Coumarin, >=99% (HPLC), DTXSID7020348, BDBM12342, KBio2_001816, KBio2_004384, KBio2_006952, KBio3_002764, ZINC74709, MolPort-000-881-054, HMS1923M11, HMS2091E19, HMS2232H18, HMS3369L08, HMS3652B05, Pharmakon1600-01400208, HY-N0709, NSC-8774, Tox21_111141, Tox21_202427, Tox21_300057, ANW-75568, BBL009203, CCG-38580, MFCD00006850, NSC755852, RW2544, s4170, SBB000094, STK066167, AKOS000120175, Tox21_111141_1, 2H-chromen-2-one (ACD/Name 4.0), CS-8148, DB04665, LS-1926, MCULE-5433669098, NE10460, NSC-755852, RTR-003307, SDCCGMLS-0066912.P001, TRA0051794, TRA0064405, KS-000046K1, NCGC00091502-02, NCGC00091502-03, NCGC00091502-04, NCGC00091502-05, NCGC00091502-06, NCGC00091502-07, NCGC00091502-08, NCGC00091502-09, NCGC00091502-11, NCGC00254092-01, NCGC00259976-01, AJ-10333, AN-24222, K669, KB-49118, NCI60_041938, R539, SC-19598, ZB002686, SBI-0061760.P002, AB1008368, DB-057267, KB-171532, Cinnamic acid, o-hydroxy-, .delta.-lactone, Coumarin, Vetec(TM) reagent grade, >=99%, FT-0606287, N1707, ST24028147, 1930-EP2269987A1, 1930-EP2270018A1, 1930-EP2270895A2, 1930-EP2272828A1, 1930-EP2272972A1, 1930-EP2272973A1, 1930-EP2275409A1, 1930-EP2276085A1, 1930-EP2277872A1, 1930-EP2278637A1, 1930-EP2284170A1, 1930-EP2284920A1, 1930-EP2287158A1, 1930-EP2292593A2, 1930-EP2295053A1, 1930-EP2295421A1, 1930-EP2298312A1, 1930-EP2298780A1, 1930-EP2298828A1, 1930-EP2299509A1, 1930-EP2299510A1, 1930-EP2299785A1, 1930-EP2301921A1, 1930-EP2305689A1, 1930-EP2305808A1, 1930-EP2306788A1, 1930-EP2306789A1, 1930-EP2308872A1, 1930-EP2309584A1, 1930-EP2311842A2, 1930-EP2316829A1, 1930-EP2316974A1, 1930-EP2371810A1, 1930-EP2371812A1, BIM-0061760.0001, C05851, D07751, 16253-EP2281563A1, 16253-EP2292593A2, 16253-EP2316459A1, 22856-EP2275469A1, 22856-EP2287159A1, 22856-EP2287940A1, 22856-EP2289965A1, 22856-EP2298774A1, 22856-EP2301926A1, 22856-EP2305808A1, 22856-EP2315502A1, 30441-EP2284170A1, 30441-EP2311835A1, 45232-EP2311806A2, AB00375898_11, AB00375898_12, Coumarin, primary pharmaceutical reference standard, CU-01000013121-2, I14-6974, Q-100890, SR-01000721887-2, SR-01000721887-3, BRD-K23913458-001-02-5, BRD-K23913458-001-13-2, Coumarin, certified reference material, TraceCERT(R), Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone, Z57169486, Coumarin, European Pharmacopoeia (EP) Reference Standard, F3096-1712, 1,2-Benzopyrone; 1-Benzopyran-2-one; 2H-Chromen-2-one, 2-Propenoic acid, 3-(2-hydroxyphenyl)-, .delta.-lactone, D3E956C4-9541-4F57-9435-7D915C38E19E, InChI=1/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6

ID: 2865

chemical graph of compound 2865



InChIKey: ZYHMJXZULPZUED-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(C=C1)OC2CCCCC2OS(=O)OCC#C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 4936
synonyms found at PubChem are:
propargite, 2312-35-8, OMITE, Comite, BPPS, 2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite, Cyclosulfyne, Omait, Uniroyal D014, Omite 57E, Omite 85E, Naugatuck D-014, Caswell No. 130I, 2-(p-tert-Butylphenoxy)cyclohexyl propargyl sulfite, U.S. Rubber D-014, 2-(p-tert-Butylphenoxy)cyclohexyl 2-propynyl sulfite, 2-(4-tert-Butylphenoxy)cyclohexyl prop-2-ynyl sulfite, Propargite [ANSI:BSI:ISO], 2-(p-t-Butylphenoxy)cyclohexyl propargyl sulfite, HSDB 1528, DO 14, 2-(4-tert-Butylphenoxy)cyclohexyl prop-2-ynyl sulphite, D 014, EINECS 219-006-1, ENT 27226, EPA Pesticide Chemical Code 097601, 2-(4-tert-Butylphenoxy)cyclohexyl 2-propynyl sulfite, AI3-27226, [2-(4-tert-butylphenoxy)cyclohexyl] prop-2-ynyl sulfite, 2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite, CHEBI:39300, Sulfurous acid, 2-(p-tert-butylphenoxy)cyclohexyl 2-propynyl ester, 2-(4-(1,1-Dimethylethyl)phenoxy)cyclohexyl 2-propynyl sulfite, 2-(4-(1,1-Dimethylethyl)phenoxy)cyclohexyl-2-propynyl sulfite, 2-(4-(1,1-Dimethylethyl)phenoxy)cyclohexyl 2-propynyl sulfurous acid, DSSTox_CID_4276, Sulfurous acid, 2-(4-(1,1-dimethylethyl)phenoxy)cyclohexyl 2-propynyl ester, Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl ester, DSSTox_RID_77352, DSSTox_GSID_24276, Propargiet, Sulfurous acid, 2-(p-tert-butylphenoxy)cyclohexyl-2-propynyl ester, CAS-2312-35-8, Propargil, C19H26O4S, Omite&reg;, Naugatuck D 014, Spectrum_001925, SpecPlus_000556, AC1Q6YPV, Spectrum2_001875, Spectrum3_000858, Spectrum4_000698, Spectrum5_002034, EC 219-006-1, AC1L1J9K, SCHEMBL15358, BSPBio_002475, KBioGR_001195, KBioSS_002467, SPECTRUM330067, DivK1c_006652, SPBio_001750, Propargite, analytical standard, CHEMBL1416084, DTXSID4024276, CTK8E6775, KBio1_001596, KBio2_002460, KBio2_005028, KBio2_007596, KBio3_001975, MolPort-003-665-462, ZYHMJXZULPZUED-UHFFFAOYSA-N, KS-000024PQ, Tox21_202046, Tox21_300805, CCG-39413, AKOS007930242, ACM2312358, DS-2860, MP-1429, Propargite 100 microg/mL in Isooctane, NCGC00094545-01, NCGC00094545-02, NCGC00094545-03, NCGC00094545-04, NCGC00094545-05, NCGC00094545-06, NCGC00094545-07, NCGC00254709-01, NCGC00259595-01, Propargite 10 microg/mL in Acetonitrile, AC-12687, AK122241, AN-50690, CC-33956, AX8149200, KB-222129, LS-148250, ST2409316, TR-010792, 4CH-007645, FT-0603603, C18602, 312P358, C-20631, I14-7446, 2-(p-tert-Butylphenoxy)cyclohexyl 2'-propynyl sulfite, 2-(4-tert-Butylphenoxy)cyclohexyl 2-propynyl sulfite #, 2-(Para-tert-butylphenoxy)cyclohexyl-2'-propynyl sulfite, Propargite, PESTANAL(R), analytical standard, technical mixture, 60098-53-5, Pesticide5_Propargite_C19H26O4 S_Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propyn-1-yl ester

ID: 2866

chemical graph of compound 2866



InChIKey: ZYVYPNZFOCZLEM-UHFFFAOYSA-N
SMILES: C1CN(CCN1)C2=CC=CC3=CC=CC=C32.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 2737391
synonyms found at PubChem are:
1-(1-Naphthyl)piperazine hydrochloride, 1-(Naphthalen-1-yl)piperazine hydrochloride, 104113-71-5, 57536-86-4, naphthylpiperazine hydrochloride, 1-naphthalen-1-ylpiperazine hydrochloride, 1-Naphthalen-1-yl-piperazine hydrochloride, Piperazine,1-(1-naphthalenyl)-, zlchem 1062, EU-0101181, AC1MC78M, MLS000859936, SCHEMBL466870, CHEMBL1256192, 1-(1-Naphthyl)piperazine HCl, CTK7D1665, ZLD0528, MolPort-000-157-702, ZYVYPNZFOCZLEM-UHFFFAOYSA-N, KS-000027JJ, Tox21_501181, AKOS005256796, 1-naphthalen-1-yl-piperazine HCl salt, CCG-222485, LF-0546, LP01181, MCULE-2765378601, N-(1-naphthyl)piperazine hydrochloride, 1-(1-Naphthyl)piperazine dihydrochloride, NCGC00094435-01, NCGC00261866-01, SMR000326797, 1-(1-naphthalenyl)piperazine hydrochloride, KB-146289, KB-180324, FT-0640467, S-003, 1-naphthalen-1-yl-piperazine monohydrochloride, 4-(naphthalen-1-yl)piperazin-1-ium chloride, 1-(1-Naphthyl)piperazine hydrochloride, needles, A831482, SR-01000075572, Piperazine, 1-(1-naphthalenyl)-, monohydrochloride, SR-01000075572-1, I14-37532, SCHEMBL15285070

ID: 2867

chemical graph of compound 2867



InChIKey: ZZGVJHSBRGZEML-UHFFFAOYSA-N
SMILES: CC(C)CCCC1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4CC5CC6C4(O3)C(C5O)(OC6(C)C)CCC(C)C(=O)O)CCC(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5149276
synonyms found at PubChem are:
DECAHYDROGAMBOGIC ACID, CHEMBL1314749, KBio1_001645, SpecPlus_000605, Spectrum4_000975, KBioGR_001349, SPECTRUM201538, DivK1c_006701, BDBM50442908, CCG-40097, SDCCGMLS-0066897.P001, NCGC00095509-01, SR-05000002770, SR-05000002770-1, BRD-A97026779-001-01-3

ID: 2868

chemical graph of compound 2868



InChIKey: ZZIKIHCNFWXKDY-GNTQXERDSA-N
SMILES: CCCCCCC(=O)CCCCCC/C=C/C[C@H]([C@@H]([C@@](CO)(C(=O)O)N)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 6438394
synonyms found at PubChem are:
Myriocin, thermozymocidin, 35891-70-4, ISP-I, ISP-1, UNII-YRM4E8R9ST, (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid, YRM4E8R9ST, Myriocin, Mycelia sterilia, Myriocin from Mycelia sterilia, CHEBI:582124, NCGC00163597-02, NCGC00163597-03, (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid, DSSTox_CID_26360, DSSTox_RID_81561, DSSTox_GSID_46360, (E,2S,3R,4R)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid, [2S,3R,4R]-(E)-2-Amino-3,4-dihydroxy-2-[hydroxymethyl]-14-oxo-6-eicosenoic Acid, 6-Eicosenoic acid, 2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-, (2S-(2R*,3S*,4S*,6E))-, CAS-35891-70-4, SR-05000002333, C21H39NO6, antibiotic ISP-I, (+)-Myriocin, Myriocin,mycella sterilia, D07MQF, AC1O5PM5, CHEMBL55076, GTPL6664, SCHEMBL6542261, SCHEMBL8499386, DTXSID9046360, BIM1005, MolPort-003-958-633, ZX-AFC000311, HMS3649I03, ZINC5782527, Tox21_112062, Tox21_113400, 1865AH, LMFA01060203, MFCD01632772, AKOS030568046, Tox21_112062_1, CCG-208239, NSC 177379, NCGC00163597-01, NCGC00163597-04, LS-63800, LS-185036, C19914, SR-05000002333-2, SR-05000002333-3, Myriocin from Mycelia sterilia, >=98% (HPLC), powder, (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid, (2S,3R,4R,E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid, [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid, 36564-60-0, 37836-36-5

ID: 2869

chemical graph of compound 2869



InChIKey: ZZORFUFYDOWNEF-UHFFFAOYSA-N
SMILES: COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5323
synonyms found at PubChem are:
sulfadimethoxine, Sulphadimethoxine, 122-11-2, Sulfadimethoxydiazine, Sulfadimethoxin, Sulfadimetoxin, Albon, Dimetazina, Sulfadimetoxina, Agribon, Deposul, Sulfadimethoxinum, Arnosulfan, Bactrovet, Diasulfa, Diasulfyl, Dimethoxysulfadiazine, Madribon, Madrigid, Madriqid, Madroxin, Madroxine, Maxulvet, Memcozine, Metoxidon, Neostrepal, Persulfen, Roscosulf, Scandisil, Sulfastop, Sulfoplan, Theracanzan, Dinosol, Dorisul, Omnibon, Radonin, Redifal, Sudine, Sulxin, Symbio, 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide, Abcid, Fuxal, Sulfadimetossina, 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, 2,6-Dimethoxy-4-sulfanilamidopyrimidine, Solfadimetossina, 2,4-Dimethoxy-6-sulfanilamido-1,3-diazine, Benzenesulfonamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-, Agribon (TN), 6-Sulfanilamido-2,4-dimethoxypyrimidine, Abcid (TN), Neostreptal, Sulfadimetoxine, Sulfadimoxine, Rofenaid, Suldixine, Sulfabon, Primor, Solfadimetossina [DCIT], UNII-30CPC5LDEX, Di-Methox, Sulfadimetossina [Italian], 2,6-Dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidine, NSC 683544, Sulfadimethoxinum [INN-Latin], Sulfadimetoxina [INN-Spanish], CHEBI:32161, EINECS 204-523-7, N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide, 30CPC5LDEX, BRN 0306856, MLS000069720, ZZORFUFYDOWNEF-UHFFFAOYSA-N, NSC683544, N(sup 1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide, 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzolsulfonamid, Sulfanilamide, N(sup 1)-(2,6-dimethoxy-4-pyrimidinyl)-, NCGC00016375-01, CAS-122-11-2, SMR000017367, DSSTox_CID_3607, DSSTox_RID_77105, DSSTox_GSID_23607, N(1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide, 4-Amino-N-[2,6-dimethoxy-4-pyrimidinyl]benzenesulfonamide, [(4-aminophenyl)sulfonyl](2,6-dimethoxypyrimidin-4-yl)amine, 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide, SULFAMED-G, Benzenesulfonamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-, monosodium salt, Sulfadimethoxine [JAN], SR-01000000227, Sulfdimethoxine, Ultrasulfon, Lasibon, Mecozine, Sumbio, Sdmo, CCRIS 9326, sulfadimethoxydiazin, Prestwick_979, Rofenaid (Salt/Mix), Spectrum_001408, Sulfadimethoxine [USP:INN:BAN:JAN:NF], Benzenesulfonamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-, sodium salt (1:1), Opera_ID_1856, Prestwick0_000728, Prestwick1_000728, Prestwick2_000728, Prestwick3_000728, Spectrum2_001419, Spectrum3_001454, Spectrum4_000442, Spectrum5_001221, CBKinase1_000256, CBKinase1_012656, Epitope ID:122237, AC1L1K3K, Cambridge id 5251398, Oprea1_486812, Oprea1_495206, SCHEMBL93845, Sulfadimethoxine (JAN/USP), BSPBio_000656, BSPBio_002947, KBioGR_000824, KBioSS_001888, 5-25-13-00290 (Beilstein Handbook Reference), MLS000103402, MLS000104965, MLS001148602, CHEMBL62193, DivK1c_000088, SPECTRUM1501144, SPBio_001498, SPBio_002595, AC1Q48V4, ARONIS018062, BPBio1_000722, component of Prazil (Salt/Mix), component of Primor (Salt/Mix), DTXSID1023607, HMS500E10, KBio1_000088, KBio2_001888, KBio2_004456, KBio2_007024, KBio3_002447, 4-Sulfa-2,6-dimethoxypyrimidine, component of Maxutrim (Salt/Mix), component of Rofenaid (Salt/Mix), MolPort-001-018-216, NINDS_000088, HMS1570A18, HMS1921J15, HMS2090P11, HMS2092F21, HMS2097A18, HMS2230L05, HMS3370K02, HMS3655H05, HMS3714A18, Pharmakon1600-01501144, component of Trivalbon (Salt/Mix), BCP15413, HY-B0337, KS-00004AC0, Tox21_110405, AN-973, BBL023015, CCG-38972, MFCD00057345, NSC757860, s1962, SBB001275, STK018258, ZINC13233295, AKOS000485038, Tox21_110405_1, API0004264, CS-2379, DB06150, KS-5335, MCULE-5924558211, NSC-683544, NSC-757860, 4-Sulfanilamido-2,6-dimethoxypyrimidine, IDI1_000088, KS-00000Z01, SMP2_000079, 2,4-Dimethoxy-6-Sulfanilamidopyrimidine, NCGC00016375-02, NCGC00016375-03, NCGC00016375-04, NCGC00016375-05, NCGC00016375-06, NCGC00016375-09, NCGC00016375-10, NCGC00024020-03, NCGC00024020-04, AC-10998, BAS 00836042, CC-34609, KB-97581, M932, ST007535, SBI-0051656.P002, AB0015456, AB1004582, BB0273640, LS-147775, 6-Sulfanilamido-2,4-dimethoxy-1,3-diazine, AB00052219, B3301, FT-0603324, S0359, T7352, 2,4-Dimethoxy-6-sulfanilamido-1,3-pyrimidine, 22S112, D01142, N1-(2.6-Dimethoxy-4-pyrimidinyl)sulfanilamide, AB00052219-15, AB00052219-17, AB00052219_18, AB00052219_19, A804847, C-19228, I06-0762, J-004764, SR-01000000227-2, SR-01000000227-4, Sulfadimethoxine, VETRANAL(TM), analytical standard, Sulfanilamide, N1-(2,6-dimethoxy-4-pyrimidinyl)-, 4-(p-Aminobenzenesulfonamido)-2,6-dimethoxypyrimidine, BRD-K71125014-001-05-7, BRD-K71125014-001-07-3, BRD-K71125014-001-17-2, N(Sup1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide, F1443-4783, Sulfadimethoxine, analytical standard, >=98.5% (TLC), 4-azanyl-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, A0400/0018451, 4-Amino-N-(2,6-dimethoxy-pyrimidin-4-yl)-benzenesulfonamide, 4-amino-N-[2,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide, Sulfadimethoxine, European Pharmacopoeia (EP) Reference Standard, Sulfadimethoxine, United States Pharmacopeia (USP) Reference Standard, Sulfadimethoxine for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 2870

chemical graph of compound 2870



InChIKey: ZZPKZRHERLGEKA-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=CC(=C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5055
synonyms found at PubChem are:
RESORCINOL MONOACETATE, 3-Hydroxyphenyl acetate, 102-29-4, Euresol, Remonol, Acetylresorcinol, 3-Acetoxyphenol, Resorcitate, m-Hydroxyphenyl acetate, 1,3-Benzenediol, monoacetate, Resorcinol, monoacetate, resorcinol acetate, Resorcin monoacetate, m-Acetoxyphenol, Resorcinol (monoacetate), Resorcin acetate, UNII-YL6O37RD1S, NSC 40511, 1,3-Benzenediol, 1-acetate, EINECS 203-022-0, (3-hydroxyphenyl) acetate, BRN 1865490, YL6O37RD1S, Resorcinol monoacetate [USP], AI3-02359, CHEBI:29672, ZZPKZRHERLGEKA-UHFFFAOYSA-N, Acetic Acid 3-Hydroxyphenyl Ester, NCGC00095054-01, DSSTox_CID_25901, DSSTox_RID_81213, DSSTox_GSID_45901, Resorcinol monoacetate (USP), CAS-102-29-4, resorcinacetate, 3-hydroxyphenyl, Resorcinol Monoacetate [USAN], Resorcinmonoacetat, resorcinmonoacetate, Resorcinol, acetate, resorcinolmonoacetate, Euresol (TN), Spectrum_001737, ACMC-20an2g, AC1L1JII, AC1Q1LAX, Spectrum3_000967, Spectrum4_001086, Spectrum5_001091, 3-Hydroxyphenyl acetate #, 1,3-benzenediol monoacetate, 1,3-Benzenediol,1-acetate, 1,3-Benznendiol monoacetate, SCHEMBL27801, BSPBio_002573, KBioGR_001472, KBioSS_002217, 4-06-00-05672 (Beilstein Handbook Reference), DivK1c_000300, SPECTRUM1503500, ZINC2029, CHEMBL1593874, DTXSID6045901, CTK3J4321, HMS500O22, KBio1_000300, KBio2_002217, KBio2_004785, KBio2_007353, KBio3_001793, MolPort-001-792-862, NINDS_000300, HMS1922C22, HMS2093G09, Pharmakon1600-01503500, Acetic acid 3-hydroxy-phenyl ester, Acetic acid, 3-hydroxyphenyl ester, HY-B0894, NSC40511, Acetylresorcinol;Resorcin monoacetate, Tox21_111406, 8061AF, CCG-40330, NSC-40511, NSC758475, AKOS015916482, Tox21_111406_1, NSC-758475, Resorcinol monoacetate, technical grade, IDI1_000300, KS-000015L4, NCGC00095054-02, NCGC00095054-03, NCGC00095054-05, ZB000465, SBI-0051828.P002, LS-143415, RT-001947, FT-0693914, R0009, C12064, D02393, AB00052359_02, SR-05000002069, J-000667, SR-05000002069-1, BRD-K85603128-001-01-9, BRD-K85603128-001-02-7, I14-49954

ID: 2871

chemical graph of compound 2871



InChIKey: ZZQHNBGRWRQWFI-XNTDXEJSSA-N
SMILES: C1=CC=C(C=C1)CCNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 5328773
synonyms found at PubChem are:
Tyrphostin AG 698, CHEMBL293749, Tyrphostin B52, NCGC00016029-01, Tyrphostin deriv. 52, Lopac-T-5193, AC1NS5B4, Lopac0_001168, MLS002172487, BDBM4306, HMS2230N17, HMS3263J17, ZINC2557956, Tox21_501168, CCG-205242, LP01168, NCGC00016029-02, NCGC00016029-03, NCGC00016029-04, NCGC00016029-05, NCGC00094426-01, NCGC00094426-02, NCGC00261853-01, SMR001254110, EU-0101168, T 5193, N-Phenethyl-alpha-cyano-3,4-dihydroxycinnamamide, SR-01000076161, J-006472, SR-01000076161-1, SR-01000076161-5, 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)acrylamide, (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenethylprop-2-enamide, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide

ID: 2872

chemical graph of compound 2872



InChIKey: ZZTCNNZHOWDRPS-UHFFFAOYSA-N
SMILES: C1CN(CCC1OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3)CCCl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 11417991
synonyms found at PubChem are:
4-Diphenylacetoxy-N-(2-chloroethyl)piperidine hydrochloride, 4-DAMP mustard hydrochloride, 130817-71-9, 130817-72-0, 4-DAMPMUSTARDHCL, EU-0100448, MLS002153428, SCHEMBL1320988, CHEMBL1256751, CTK8E4979, AKOS030548816, NCGC00093864-01, SMR001230803, RT-009644, SR-01000075847, J-005885, SR-01000075847-1, 4-diphenylacetoxy-N-[2-chloroethyl] piperidine hydrochloride

ID: 2873

chemical graph of compound 2873



InChIKey: ZZUFCTLCJUWOSV-UHFFFAOYSA-N
SMILES: C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 3440
synonyms found at PubChem are:
furosemide, 54-31-9, Frusemide, Lasix, Furosemid, Furanthril, Errolon, Fusid, Aisemide, Beronald, Desdemin, Frusemin, Fuluvamide, Furanthryl, Furantril, Fursemide, Lowpstron, Macasirool, Prefemin, Rosemide, Trofurit, Fulsix, Furesis, Katlex, Lasilix, Radonna, Seguril, Transit, Lasex, Salix, Urex, Eutensin, Frusetic, Fursemid, Promedes, Frusid, Lazix, Frusemid, Frusenex, Furanturil, Furosedon, Profemin, Urosemide, Aluzine, Diural, Dryptal, Impugan, Rusyde, Uremide, Uresix, Yidoli, Disal, Laxur, Urian, Apo-Frusemide, Hydro-rapid, Anfuramaide, Arasemide, Bioretic, Disemide, Diurapid, Diurolasa, Diusemide, Durafurid, Fluidrol, Frusedan, Fuluvamine, Furobeta, Furodiurol, Furodrix, Furorese, Furosemidu, Furosemidum, Furosemix, Furoside, Furosifar, Furovite, Fursemida, Hissuflux, Hydroled, Jenafusid, Lasiletten, Logirene, Lowpston, Marsemide, Moilarorin, Novosemide, Protargen, Radisemide, Selectofur, Sigasalur, Spirofur, Synephron, Zafimida, Aldalix, Aquarid, Aquasin, Cetasix, Dirine, Discoid, Diurin, Diusil, Diuzol, Dranex, Edemid, Edenol, Endural, Farsix, Franyl, Frumex, Frumide, Frusema, Furetic, Furfan, Furmid, Furocot, Furomen, Furomex, Furosan, Furose, Furosix, Furoter, Fursol, Hydrex, Kofuzon, Kolkin, Kutrix, Lasemid, Liside, Luscek, Mirfat, Nelsix, Odemase, Odemex, Oedemex, Promide, Puresis, Radouna, Salinex, Salurex, Salurid, Uridon, Uritol, Aldic, Depix, Desal, Eliur, Fluss, Furex, Furix, Golan, Hydro, Nadis, Retep, Rosis, Vesix, Mita, Apo-Furosemide, Furo-puren, Lasix Retard, Polysquall A, less Diur, Neo-renal, Furo-Basan, Furosemida, Urex-M, Nephron, 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid, Furomide M.D., Frumil, Furosemidu [Polish], Furosemidum [INN-Latin], Furosemida [INN-Spanish], LB 502, Furantral, Myrosemide, 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid, Sal diureticum, Diumide-K, Furosemide "mita", NCI-C55936, 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid, Lasix (TN), fulvamide, LB-502, 5-(Aminosulfonyl)-4-chloro-2-[(2-furylmethyl)amino]benzoic acid, Octan draselny, Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-, Lasix Special, Fu sid, UNII-7LXU5N7ZO5, Furomide M.D, C12H11ClN2O5S, Furosemide [USAN:INN:JAN], 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid, CCRIS 1951, Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure, furosemide ''mita'', FUROSEMIDE USP, Anthranilic acid, 4-chloro-N-furfuryl-5-sulfamoyl-, HSDB 3086, CHEMBL35, EINECS 200-203-6, 4-Chloro-2-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid, 4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid, Hoe-058A, NSC 269420, Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)-, BRN 0840915, 7LXU5N7ZO5, 106391-48-4, Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure [German], CHEBI:47426, ZZUFCTLCJUWOSV-UHFFFAOYSA-N, 5-(Aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid, 5-(Aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid, CAS-54-31-9, NCGC00016241-06, 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid, DSSTox_CID_648, F0182, DSSTox_RID_75710, DSSTox_GSID_20648, FUN, 4-chloro-2-(2-furylmethylamino)-5-sulfamoyl-benzoic acid, 4-chloro-2-[(2-furylmethyl)amino]-5-sulfamoylbenzoic acid, Furosemide mita, Furosemide oral, 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid, 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(furan-2-ylmethyl)amino]benzoic acid, 5-[Aminosulfonyl]-4-chloro-2-[(2-furanylmethyl)-amino]benzoic acid, SMR000058202, SR-01000765380, Furosemide Monosodium Salt, Furosemide Monohydrochloride, Neosemid, Zafurida, Lasix;Frusemide, furosemide(lasix), Furosemide, 4, Fuluvamide (TN), Hydro-rapid(TN), Macasirool (TN), Durafurid (TN), Furosedon (TN), Furosemide (mita), Urex M, Aisemide (TN), Beronald (TN), Desdemin (TN), Diurapid (TN), Eutensin (TN), Frusetic (TN), furosemide (lasix), Lowpston (TN), Profemin (TN), Rosemide (TN), Trofurit (TN), Prestwick_752, Discoid (TN), Dryptal (TN), Errolon (TN), Furesis (TN), Furosemide(Lasix)/, Impugan (TN), Lasilix (TN), Nicorol (TN), Odemase (TN), Oedemex (TN), Furo-Puren (TN), Diural (TN), Frudix (TN), Frumil (Salt/Mix), Frusid (TN), Fulsix (TN), Katlex (TN), Mirfat (TN), Rusyde (TN), Furix (TN), Lodix (TN), Salix (TN), PubChem7165, Furosemide [USAN:USP:INN:BAN:JAN], Apo-Furosemide (TN), Spectrum_001100, 1z9y, AC1L1FXW, Prestwick0_000341, Prestwick1_000341, Prestwick2_000341, Prestwick3_000341, Spectrum2_001005, Spectrum3_000437, Spectrum4_000560, Spectrum5_000744, ACMC-20e7w6, D0PQ3G, UPCMLD-DP022, SCHEMBL9811, Salix (brand of furosemide), Oprea1_667724, BSPBio_000401, BSPBio_002054, KBioGR_001259, KBioSS_001580, Lasix, Frusemide, Furosemide, 5-18-09-00555 (Beilstein Handbook Reference), KSC181M1P, MLS001066374, MLS001306403, MLS002548896, ARONIS24304, BIDD:GT0139, DivK1c_000575, F4381_SIGMA, SPECTRUM1500310, SPBio_001129, SPBio_002322, AC1Q557O, BPBio1_000443, Furosemide (JP15/USP/INN), Furosemide (JP17/USP/INN), GTPL4839, DTXSID6020648, UPCMLD-DP022:001, BDBM25902, CTK0I1617, HMS501M17, KBio1_000575, KBio2_001580, KBio2_004148, KBio2_006716, KBio3_001274, ZINC35804, BBC/460, MolPort-001-641-065, NINDS_000575, HMS1569E03, HMS1920B03, HMS2090K06, HMS2091H05, HMS2096E03, HMS2233H03, HMS3259M03, HMS3370J22, HMS3655E09, HMS3713E03, Pharmakon1600-01500310, Furosemide 1.0 mg/ml in Methanol, ALBB-019200, HY-B0135, ZX-AN034923, ZX-AS004664, ZX-AT016383, Tox21_110322, Tox21_202213, Tox21_302971, ABP000639, BBL027780, BG0201, CCG-40223, MFCD00010549, NSC269420, NSC757039, OR5475, SBB012613, STK177334, WLN: T5OJ B1MR CG FVQ DSZW, AKOS000266625, Tox21_110322_1, API0002772, BCP9000708, CS-1915, DB00695, KS-1226, MCULE-8037874224, NC00453, NSC-269420, NSC-757039, IDI1_000575, SMP1_000129, NCGC00016241-01, NCGC00016241-02, NCGC00016241-03, NCGC00016241-04, NCGC00016241-05, NCGC00016241-07, NCGC00016241-08, NCGC00016241-10, NCGC00016241-11, NCGC00090893-01, NCGC00090893-02, NCGC00090893-03, NCGC00090893-05, NCGC00090893-06, NCGC00256523-01, NCGC00259762-01, 41733-55-5 (mono-hydrochloride salt), AC-11067, AN-16917, BC201654, BP-13261, CC-28906, CPD000058202, H788, SAM002264614, SC-05214, ST005581, SBI-0051389.P003, AB0007947, AB2000153, RT-000186, TL8003563, AB00052001, FT-0603229, 54F319, C07017, D00331, J10011, K-9798, AB00052001-10, AB00052001-11, AB00052001_12, AB00052001_13, A830094, C-20036, I04-0179, SR-01000765380-2, SR-01000765380-3, SR-01000765380-7, BRD-K78010432-001-05-8, BRD-K78010432-001-10-8, Z275128584, 4-chloro-2-(2-furanylmethylamino)-5-sulfamoylbenzoic acid, Furosemide, British Pharmacopoeia (BP) Reference Standard, Furosemide, European Pharmacopoeia (EP) Reference Standard, 4-chloranyl-2-(furan-2-ylmethylamino)-5-sulfamoyl-benzoic acid, Furosemide, United States Pharmacopeia (USP) Reference Standard, 4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID pound>>Fu, 5-(Aminosulfamyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid, 5-(Aminosulfonyl)-4-chloro-2-[(2-furylmethyl)amino]benzoic acid #, 4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID pound>>Furosemide, Furosemide, Pharmaceutical Secondary Standard; Certified Reference Material, Furosemide for peak identification, European Pharmacopoeia (EP) Reference Standard, STL455072, 4-chloro-2-[(furan-2-ylmethyl)ammonio]-5-sulfamoylbenzoate

ID: 2874

chemical graph of compound 2874



InChIKey: ACMPJJXJGXDZQQ-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2875

chemical graph of compound 2875



InChIKey: AQWKVJFRGORALM-UHFFFAOYSA-N
SMILES: OC1=CC=C(C)C=C1C2=NNC(C3=CC=CC=C3)=C2

biological descriptors:

CFTR relevance: CFTR chaperone and potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"MC Bartlett" "DM Clarke" "TW Loo" "Y Wang"


CID is 781239

ID: 2876

chemical graph of compound 2876



InChIKey: AWSYHYROGLLOKT-GXDHUFHOSA-N
SMILES: C(/C=N/O)1C(CCC=C)=NN(C)C=1OCCCC

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2877

chemical graph of compound 2877



InChIKey: AXBFLDGTEBSJDR-UHFFFAOYSA-N
SMILES: C(C([HH0])=O)1C(C2=CC=CC=C2)=NN(C)C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 86059026

ID: 2878

chemical graph of compound 2878



InChIKey: AYSBGNFXZVMBFB-LCYFTJDESA-N
SMILES: C(/C(/[HH0])=N\O)1C(CCC=C)=NN(C)C=1OCCC

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2879

chemical graph of compound 2879



InChIKey: AZELSOYQOIUPBZ-UHFFFAOYSA-N
SMILES: COc1cc2c(cc1O)c(cc(=O)o2)c3ccccc3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "J Goepp" "B Kus" "D Rotin" "E Matthes" "DY Thomas" "SD Macknight" "R Robert" "J Liao"


CID is 442768
synonyms found at PubChem are:
Dalbergin, 482-83-7, 6-Hydroxy-7-methoxy-4-phenylcoumarin, 2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-4-phenyl-, CHEBI:4308, 6-hydroxy-7-methoxy-4-phenyl-2H-chromen-2-one, 6-hydroxy-7-methoxy-4-phenylchromen-2-one, AC1L9DDQ, C10414, SCHEMBL620349, CHEMBL1829658, CTK8D4059, DTXSID60331943, AZELSOYQOIUPBZ-UHFFFAOYSA-N, ZINC899783, LMPK12100003, MFCD00075721, AKOS015856200, ZB015167, KB-248863, TC-071472, 6-Hydroxy-7-methoxy-4-phenyl-chromen-2-one, FT-0660660, ST50308886, C-54609

ID: 2880

chemical graph of compound 2880



InChIKey: BAVRWDCSJSFVNJ-LDADJPATSA-N
SMILES: C1=CC=C(C=C1)N/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]

biological descriptors:

CFTR relevance: CFTR chaperone binding to NBD1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"JW Hanrahan" "GW Carlile" "HM Sampson" "E Matthes" "DY Thomas" "R Robert" "J Liao"


CID is 9566157
synonyms found at PubChem are:
5-(4-Nitrophenyl)-2-furaldehyde 2-phenylhydrazone, (1E)-1-{[5-(4-nitrophenyl)furan-2-yl]methylidene}-2-phenylhydrazine, CHEMBL3585378, CCG-684, BAVRWDCSJSFVNJ-LDADJPATSA-N, MolPort-001-828-272, STK001879, AKOS001588752, 5-(4-Nitrophenyl)-2-furaldehyde phenylhydrazone #, SR-01000631014-1

ID: 2881

chemical graph of compound 2881



InChIKey: BAYMNCHSODLCJV-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=C2)S(=O)(=O)NC3=CC=C(C=C3)C(=O)O)C(=C1)N

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 235593
synonyms found at PubChem are:
NSC37173, NSC-37173, CHEMBL221733, 6305-91-5, 4-{[(5-aminonaphthalen-2-yl)sulfonyl]amino}benzoic acid, 4-[(5-aminonaphthalen-2-yl)sulfonylamino]benzoic acid, D0B3XP, AC1L5UQ8, AC1Q6VU5, NCIStruc1_001028, NCIStruc2_001521, CTK5B7325, DTXSID10284415, NCI37173, ZINC1669798, BDBM50158388, CCG-36845, NCGC00013434, AKOS030548133, NCGC00013434-02, NCGC00096549-01, NCI60_003431, 4-(1-aminonaphthalene-6-sulfonamido)benzoic acid, 4-(5-aminonaphthalene-2-sulfonamido)benzoic acid, 4-(((5-amino-2-naphthyl)sulfonyl)amino)benzoic acid

ID: 2882

chemical graph of compound 2882



InChIKey: BFBZAASQFWNNIU-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC=C2OC)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2883

chemical graph of compound 2883



InChIKey: BGOJJHGVMOOKAU-UHFFFAOYSA-N
SMILES: C1C2=CC=CC=C2C3=C1C=C(C=C3)NC(=O)C4=C(C=CC(=C4)C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector, pocket 2

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 252007
synonyms found at PubChem are:
NSC73100, AC1L5L3Q, NCIStruc1_001290, NCIStruc2_001412, SCHEMBL806014, CHEMBL1412139, CTK7F5945, NCI73100, ZINC1698877, CCG-37000, NCGC00013802, NCGC00013802-02, NCGC00096912-01, NCI60_041594, 2-(9H-fluoren-2-ylcarbamoyl)terephthalic acid, 2-((9H-fluoren-2-ylamino)carbonyl)terephthalic acid, 2-(9h-fluoren-2-ylcarbamoyl)benzene-1,4-dicarboxylic acid

ID: 2884

chemical graph of compound 2884



InChIKey: BLLINNMWOCXNKA-UHFFFAOYSA-M
SMILES: [NH0+](CC1CCC(CO)CC1)1C=CC=CC=1.[ClH0-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2885

chemical graph of compound 2885



InChIKey: BOBBZTCRILASNM-UHFFFAOYSA-N
SMILES: C12C=CC=CC=1C=CC1C(=O)C=C(C3=C(C4=CC=CC(N)=C4)C=CC=C3)OC2=1

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2886

chemical graph of compound 2886



InChIKey: BOFFDTYASKWXTL-IFMALSPDSA-N
SMILES: Cc1ccc2c(c1)O[C@H](C[C@H]2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6cccc(c6)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301079
synonyms found at PubChem are:
SCHEMBL17708747, BOFFDTYASKWXTL-IFMALSPDSA-N, 3-[(2R,4R)-4-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-methyl-3,4-dihydro-2H-chromen-2-yl]benzoic acid

ID: 2887

chemical graph of compound 2887



InChIKey: BPXKJGXZDJAJEW-UHFFFAOYSA-N
SMILES: C2=CC1=C([N]C(=C1Br)C)C(=O)NC2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "Q Yang" "CM Edge" "V Birault" "E Matthes" "DY Thomas" "R Hatley" "R Andersen" "R Robert" "R Solari"


ID: 2888

chemical graph of compound 2888



InChIKey: BXIUMZGBYAQASY-HFYYSOHNSA-N
SMILES: N(CC(C)F)1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1

biological descriptors:

CFTR relevance: Non-effective CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Désiré" "A Mingot" "S Thibaudeau" "F Becq" "Y Blériot" "V Cendret" "A Kato" "M Forcella" "I Adachi" "C Norez" "T Legigan" "P Parenti" "J Bertrand"


ID: 2889

chemical graph of compound 2889



InChIKey: BXSABLKMKAINIU-QOHCMMFCSA-N
SMILES: C[C@]12C[C@H]([C@H]3[C@H]([C@]1(CC[C@@H]2C4=CC(=O)OC4)O)CC[C@]5([C@@]3([C@@H](C[C@@H](C5)O)O)CO)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"A Luini" "JW Hanrahan" "GW Carlile" "SM Anjos" "F Ciciriello" "DY Thomas" "D Zhang" "A Carissimo" "H Balghi" "R Robert" "J Liao"


CID is 12313812
synonyms found at PubChem are:
Ouabagenin, g-Strophanthidin, 508-52-1, UNII-R2692W2T67, Ouabain genin, CHEBI:71016, R2692W2T67, 1beta,3beta,5,11alpha,14,19-Hexahydroxy-5beta-card-20(22)-enolide, NSC 97088, BRN 0060306, 1-beta,3-beta,5,11-alpha,14,19-Hexahydroxy-5-beta-card-20(22)-enolide, Ouabagenin, >=95%, 4-18-00-03554 (Beilstein Handbook Reference), SCHEMBL643840, CHEMBL2068926, 5-beta-Card-20(22)-enolide, 1-beta,3-beta,5,11-alpha,14,19-hexahydroxy-, ZINC13475048, 1|A,3|A,5,11|A,14,19-Hexahydroxy-5|A-card-20(22)-enolide, 1 beta,3beta,5alpha,11alpha,14,19-Hexa-hydroxy-5 beta,20[22]-cardenolide, 5beta-Card-20(22)-enolide, 1beta,3beta,5,11alpha,14,19-hexahydroxy- (8CI), 4-[(1S,2R,3R,5S,7S,10R,11S,14R,15R,17R)-3,5,7,11,17-pentahydroxy-2-(hydroxymethyl)-15-methyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]-5H-furan-2-one, Card-20(22)-enolide, 1,3,5,11,14,19-hexahydroxy-, (1-beta,3-beta,5-beta,11-alpha)- (9CI)

ID: 2890

chemical graph of compound 2890



InChIKey: BZRSNJXOHYRQSB-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2(C4=CC=C(C=C4)Cl)SCC(C(=O)O)N

biological descriptors:

CFTR relevance: CFTR corrector, pocket 2

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 276215
synonyms found at PubChem are:
NSC123526, MLS002707308, s-[9-(4-chlorophenyl)-9h-fluoren-9-yl]cysteine, 27486-80-2, 2-amino-3-{[9-(4-chlorophenyl)-9H-fluoren-9-yl]sulfanyl}propanoic acid, S-(9-(4-chlorophenyl)-9H-fluoren-9-yl)cysteine, AC1L5JCI, AC1Q3NO8, SCHEMBL3473170, CHEMBL1898204, DTXSID00298506, NCI60_000557, SMR001574700, 2-amino-3-[9-(4-chlorophenyl)fluoren-9-yl]sulfanylpropanoic acid

ID: 2891

chemical graph of compound 2891



InChIKey: CGKULGRKHMORMQ-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC=C1C(C(C(=O)OC(C)(C)C)CN1CCCCC1)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2892

chemical graph of compound 2892



InChIKey: CJFNUDMDMGMQSU-UHFFFAOYSA-N
SMILES: C1=CC=C(OC)C(OC)=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2893

chemical graph of compound 2893



InChIKey: CMFNMSMUKZHDEY-UHFFFAOYSA-M
SMILES: N(=O)O[O-]

biological descriptors:

CFTR relevance: PARP-1 activator

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction indirect
subcellular compartment Nucleus (Transcription)

reference list:

"D Waller" "J Goepp" "SM Anjos" "F Ciciriello" "R Phillipe" "R Robert" "J Liao" "F Dantzer" "JW Hanrahan" "DL Zhang" "GW Carlile" "HM Sampson" "DY Thomas" "P Ferraro" "H Balghi" "P Lesimple"


CID is 104806
synonyms found at PubChem are:
oxido nitrite, 19059-14-4, Peroxynitrite (8CI,9CI), Oxoperoxonitrate(1-), Peroxonitrous acid anion, ONOO-, oxidoperoxidonitrate(1-), AC1L2XJ8, Peroxynitrosyl (NO3) (6CI), CHEBI:25941, CTK0H5961, DTXSID10172540, CMFNMSMUKZHDEY-UHFFFAOYSA-M, [NO(OO)](-), LS-102485, C16845

ID: 2894

chemical graph of compound 2894



InChIKey: CQMIFESSLNOXAB-UHFFFAOYSA-N
SMILES: C(C(=O)OC1=C(C(=O)C)C(OC(=O)C2=C(F)C=CC=C2)=CC=C1)1=CC=CC=C1F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2895

chemical graph of compound 2895



InChIKey: CTPJRBCFXXWXOH-UHFFFAOYSA-M
SMILES: [IH0-].N(C)1C2C=CC=CC=2N2C([HH0])=[NH0+]3C4C=CC=CC=4N(C)C3=NC12

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2896

chemical graph of compound 2896



InChIKey: CUQLSENJIWKESD-UHFFFAOYSA-N
SMILES: C(C(=O)OCC)1C(C2=CC=CC=C2)NNC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 12868893

ID: 2897

chemical graph of compound 2897



InChIKey: CZHKNJDXPPNMFV-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)C3=CC(=C(C=C3)C)C

biological descriptors:

CFTR relevance: CFTR corrector, pocket 2

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 266881
synonyms found at PubChem are:
NSC105687, NSC-105687, N-(2-(3,4-dimethylbenzoyl)phenyl)-4-methylbenzenesulfonamide, N-[2-(3,4-dimethylbenzoyl)phenyl]-4-methylbenzenesulfonamide, AC1L6H0U, NCIStruc1_001377, NCIStruc2_001114, CHEMBL1443168, ZINC1691755, CCG-37452, NCGC00014077, NCI105687, NCGC00014077-02, NCGC00097186-01, NCI60_000136

ID: 2898

chemical graph of compound 2898



InChIKey: CZMBBESMLWNVEM-UHFFFAOYSA-N
SMILES: C(C([HH0])=O)1C(CCC=C)=NN(C)C=1OCCC

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2899

chemical graph of compound 2899



InChIKey: DFVMSKLJAKHGHK-UHFFFAOYSA-N
SMILES: C1(=CC=CO1)C(=O)OC1=C(C(=O)C)C(OC(=O)C2=CC=CO2)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2900

chemical graph of compound 2900



InChIKey: DGNDJPPKJOAWAC-GWQXNCQPSA-N
SMILES: c1ccc2c(c1)C(C[C@@H](O2)c3cccc(c3)CO)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301194
synonyms found at PubChem are:
SCHEMBL17708875, DGNDJPPKJOAWAC-GWQXNCQPSA-N, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-{(2R)-2-[3-(hydroxymethyl)phenyl]-3,4-dihydro-2H-chromen-4-yl}cyclopropanecarboxamide

ID: 2901

chemical graph of compound 2901



InChIKey: DHLQGNWAQFDXPO-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C(C)=C(C3=CC=C(I)C=C3)OC1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2902

chemical graph of compound 2902



InChIKey: DIKVHTCRLXZEJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)[N+](=O)[O-])CSC2=NC(=O)C3=C(N2)N=CN3

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 3246417
synonyms found at PubChem are:
2-((3-Nitrobenzyl)thio)-9H-purin-6-ol, 15870-55-0, NSC118208, NSC-118208, 2-((3-nitrobenzyl)thio)-3H-purin-6(7H)-one, AC1MMYGF, NCIStruc1_001314, NCIStruc2_001113, CHEMBL1568233, SCHEMBL16318809, DTXSID00390574, MolPort-038-940-924, ZINC7996341, CCG-36621, NCGC00014199, NCI118208, NSC211342, AKOS024464712, AKOS025328668, NSC-211342, 2-(3-nitrobenzylthio)-9H-purin-6-ol, NCGC00014199-02, NCGC00097308-01, AK162280, NCI60_000435, AX8294627, 2-(3-nitrobenzylthio)-3H-purin-6(7H)-one, 2-((3-(hydroxy(oxido)amino)benzyl)thio)-9H-purin-6-ol, F9994-0116, 2-[(3-nitrophenyl)methylsulfanyl]-3,7-dihydropurin-6-one

ID: 2903

chemical graph of compound 2903



InChIKey: DJJHVHJQNMBUEX-UHFFFAOYSA-N
SMILES: C1=CC=CC(C(=O)CC)=C1OC(=O)C1=CC=C(F)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2904

chemical graph of compound 2904



InChIKey: DKDSDCUGRXTFJJ-UHFFFAOYSA-N
SMILES: C12C=CC=CC=1C=CC1C(=O)C=C(C3=C(C4=CC=CC=C4)C=CC=C3)OC2=1

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2905

chemical graph of compound 2905



InChIKey: DQZKLTAELTVXRE-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=O)OC2=CC(OC(=C)C3=CC=CC=C3F)=C(C(=O)C)C=C2)C(F)=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2906

chemical graph of compound 2906



InChIKey: DXWHZJXKTHGHQF-UHFFFAOYSA-N
SMILES: CCCCNC1=C2C=CC=C3C2=C(C=C1)C(=O)N(C3=O)CCCC

biological descriptors:

CFTR relevance: Weak PARP-1 inhibitor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Nucleus (Transcription)

reference list:

"D Waller" "J Goepp" "SM Anjos" "F Ciciriello" "R Phillipe" "R Robert" "J Liao" "F Dantzer" "JW Hanrahan" "DL Zhang" "GW Carlile" "HM Sampson" "DY Thomas" "P Ferraro" "H Balghi" "P Lesimple"


CID is 87935
synonyms found at PubChem are:
Solvent Yellow 43, 19125-99-6, MLS000780025, 2-Butyl-6-(butylamino)-1H-benz(de)isoquinoline-1,3(2H)-dione, SMR000420208, 12226-96-9, 2-Butyl-6-butylamino-benzo[de]isoquinoline-1,3-dione, 2-butyl-6-(butylamino)benzo[de]isoquinoline-1,3-dione, DXWHZJXKTHGHQF-UHFFFAOYSA-N, 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-butyl-6-(butylamino)-, 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-butyl-6-(butylamino)-, EINECS 242-828-7, 4-Butylamino-N-butyl-1,8-naphthalimide, 4-(Butylamino)-N-butyl-1,8-naphthalimide, AC1L3EPE, AC1Q6JKW, C.I.Solvent Yellow 43, cid_87935, SCHEMBL372370, CHEMBL1472131, DTXSID3051830, BDBM51269, MolPort-000-725-928, HMS2801M18, ZINC4344110, CCG-46786, STK530702, AKOS003611595, MCULE-8597348586, n-butyl-4-butylamino-1,8-naphthalimide, NCGC00246448-01, 4-(Butylamino)-N-butyl-1,8-naphthalenedicarbimide, SR-01000636460-1, 2-butyl-6-(butylamino)benzo[de]isoquinoline-1,3-quinone, 2-butyl-6-(butylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione, 103598-93-2, 11118-22-2, 12765-30-9, 199396-78-6, 39471-51-7, 85537-62-8

ID: 2907

chemical graph of compound 2907



InChIKey: FAAJBDQTQFYAJA-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)C(CC(O2)c3ccc(cc3)Cl)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301400
synonyms found at PubChem are:
SCHEMBL17709097

ID: 2908

chemical graph of compound 2908



InChIKey: FAXXFIOVHFSKRF-ZVBGSRNCSA-N
SMILES: C1=CC(=C(C=C1N/N=C/C2=CC=C(O2)C3=C(C=C(C=C3)[N+](=O)[O-])Br)C(=O)O)Cl

biological descriptors:

CFTR relevance: CFTR chaperone binding to NBD1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"JW Hanrahan" "GW Carlile" "HM Sampson" "E Matthes" "DY Thomas" "R Robert" "J Liao"


CID is 9604668
synonyms found at PubChem are:
MolPort-002-161-272

ID: 2909

chemical graph of compound 2909



InChIKey: FCLIHRPKEBQSNV-UHFFFAOYSA-N
SMILES: [BrH0-].C1=CC(C)=C2NCC[NH0+]2=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2910

chemical graph of compound 2910



InChIKey: FFIONGKVUNGDJS-UHFFFAOYSA-N
SMILES: C1(=C(OCC2=CC=C(OC)C=C2)C=CC=C1)C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2911

chemical graph of compound 2911



InChIKey: FGRUYVALZXMMSO-UHFFFAOYSA-N
SMILES: C1C2C(CC3C=CC=CC=3)C(C3=CC=CC=C3)=CC(=S)C=2C=CC=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2912

chemical graph of compound 2912



InChIKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

biological descriptors:

CFTR relevance: CFTR corrector, pocket 2

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 3151
synonyms found at PubChem are:
domperidone, 57808-66-9, Motilium, Nauzelin, Domperidonum, Domperidona, Domperidon, Motinorm, Costi, Domperidonum [INN-Latin], Domperidona [INN-Spanish], Motillium, R-33812, NSC299589, Motilium (TN), KW-5338, R 33,812, Domperidone (Motilium), Lopac-D-122, 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine, Domperidone [USAN:BAN:INN:JAN], Domperidone Maleate, EINECS 260-968-7, UNII-5587267Z69, KW 5338, BRN 0903774, 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone, MLS000069343, CHEMBL219916, CHEBI:31515, R-33,812, NCI299589, 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one, NSC-299589, HS-0067, D-122, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone, DSSTox_CID_25116, DSSTox_RID_80682, DSSTox_GSID_45116, 2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-, 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, W-105440, 5587267Z69, 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, 2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one, SMR000326802, CAS-57808-66-9, SR-01000003002, peridon, Nauzelin OD, Domperidone,(S), domperidone betadex, Motillium (TN), Motinorm (TN), 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-{1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, Domperidone [USAN:INN:BAN:JAN], Prestwick_794, Domperidone,Motilium, Costi (TN), PubChem15679, Spectrum_000391, Opera_ID_616, SpecPlus_000825, AC1L1FAB, Prestwick0_000461, Prestwick1_000461, Prestwick2_000461, Prestwick3_000461, Spectrum4_000087, domperidone betacyclodextrin, Biomol-NT_000022, D0AV3G, NCIStruc1_001686, NCIStruc2_001819, Lopac0_000427, SCHEMBL43729, BSPBio_002350, GTPL965, KBioGR_000354, KBioSS_000871, 5-24-02-00402 (Beilstein Handbook Reference), MLS000859942, MLS001306482, MLS002222324, DivK1c_006921, SPECTRUM2300212, SPBio_002501, Domperidone (JAN/USAN/INN), BPBio1_000620, BPBio1_001185, DTXSID1045116, CTK8B3352, Domperidone (JP17/USAN/INN), KBio1_001865, KBio2_000871, KBio2_003439, KBio2_006007, KS-00000PNZ, BBC/763, 99497-03-7 (maleate), FGXWKSZFVQUSTL-UHFFFAOYSA-N, MolPort-003-666-773, HMS1922N04, HMS2089C14, HMS2093N22, HMS2096C21, HMS2230N18, HMS3261E16, HMS3269O13, HMS3370L03, HMS3656M21, HMS3713C21, Pharmakon1600-02300212, BCP28265, Domperidone 1.0 mg/ml in Methanol, EBD46624, HY-B0411, ZINC4175569, ZX-AS004963, Tox21_110056, Tox21_500427, ANW-42358, BBL028136, BDBM50241107, BG0172, CCG-37870, CD0227, GP3849, MFCD00069256, NCGC00014670, NSC759575, s2461, STK622843, AKOS005555858, Tox21_110056_1, AC-2037, AN-5531, CS-2511, DB01184, Domperidone, powder, >=98% (HPLC), LP00427, MCULE-4430288884, NSC-759575, NCGC00014670-01, NCGC00014670-02, NCGC00014670-03, NCGC00014670-04, NCGC00014670-05, NCGC00014670-06, NCGC00014670-07, NCGC00014670-08, NCGC00014670-09, NCGC00014670-10, NCGC00014670-11, NCGC00014670-12, NCGC00014670-13, NCGC00014670-14, NCGC00014670-16, NCGC00014670-17, NCGC00015306-01, NCGC00021472-02, NCGC00021472-03, NCGC00021472-04, NCGC00021472-05, NCGC00021472-06, NCGC00021472-07, NCGC00021472-08, NCGC00097773-01, NCGC00261112-01, LS-33301, NCI60_002512, SC-18462, SMR000058969, 83898-65-1 (maleate (1:1)), AB0110085, AB1009278, AB00052423, D4125, EU-0100427, FT-0625588, D01745, AB00052423-06, AB00052423-07, AB00052423_08, AB00052423_09, 808D669, L000230, R 33812, I01-0054, SR-01000003002-2, SR-01000003002-4, SR-01000003002-7, BRD-K38305202-001-02-6, BRD-K38305202-001-08-3, I14-14161, Domperidone, European Pharmacopoeia (EP) Reference Standard, 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one, 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]-4-piperidyl]-1H-benzimidazol-2-one, 2H-Benzimidazol-2-one,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-2H-1,2,4-triazol-3(4H)-one, 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]- 1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1- yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidine-4-yl]-1,3-dihydro-2H-benzimidazol-2-one;, 5-chloro-1-{1-[3(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-{1-[3-(1,3-dihydro-2-oxo-2H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, 5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one, 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone), DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one

ID: 2913

chemical graph of compound 2913



InChIKey: FUFUPUBTKUKWJT-UHFFFAOYSA-N
SMILES: C1=CC=CC(C(=O)CC)=C1OC(=O)C1=CC(F)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2914

chemical graph of compound 2914



InChIKey: FWLFUQFVVJVAJR-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)C(CC(O2)c3cccc(c3)Cl)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301402
synonyms found at PubChem are:
SCHEMBL17709099

ID: 2915

chemical graph of compound 2915



InChIKey: FYLYSEXHKNLCOF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)P(=O)(CCP(=O)(C2=CC=CC=C2)O)O

biological descriptors:

CFTR relevance: CFTR corrector, pocket 2

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 348520
synonyms found at PubChem are:
NSC407882, 1089-77-6, NSC-407882, AC1L89QR, NCIStruc1_001723, NCIStruc2_001208, SCHEMBL806049, diphenylethylenediphosphinic acid, CHEMBL1742186, 1,2-Bis(phenylphosphonyl)ethane, DTXSID90324863, ZINC1600154, CCG-37062, NCGC00014903, NCI407882, AKOS030621632, NCGC00014903-02, NCGC00098004-01, NCI60_003901, Ethane-1,2-diylbis(phenylphosphinic acid), 2-(hydroxy-phenyl-phosphoryl)ethyl-phenyl-phosphinic acid, 2-[hydroxy(phenyl)phosphoryl]ethyl-phenylphosphinic acid, {2-[hydroxy(phenyl)phosphoryl]ethyl}(phenyl)phosphinic acid

ID: 2916

chemical graph of compound 2916



InChIKey: GALYZWCGYCEXNA-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2917

chemical graph of compound 2917



InChIKey: GOVKKBWDALWZGY-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3=CC=CC(F)=C3)C([HH0])C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2918

chemical graph of compound 2918



InChIKey: GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CN2)C=C1C(=O)N

biological descriptors:

CFTR relevance: α-site binder

Category:
Influence on CFTR function unknown
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"LJ Byrnes" "H Wang" "JD Hall" "JD Forman-Kay" "AE Aulabaugh" "PA Chong" "IV Efremov" "S Shanker" "K Wang"


CID is 14973220
synonyms found at PubChem are:
1H-Indole-5-carboxamide, 1670-87-7, Indole-5-carboxamide, SD169, SD-169, 5-Carboxamidoindole, SD 169, 5-Carbamoylindole, MLS006010711, 5-(Aminocarbonyl)-1H-indole, SCHEMBL170646, CHEMBL1435541, BDBM93020, CHEBI:93599, CTK0H1666, 1H-Indole-5-carboxamide, 97%, DTXSID50566323, SYN1079, GQMYQEAXTITUAE-UHFFFAOYSA-N, MolPort-004-768-623, HMS3229J11, HMS3244I21, HMS3244I22, HMS3244J21, HMS3262M03, HMS3267H21, BCP01964, Tox21_500701, ABP000279, RS0058, ZINC13816304, AKOS013029770, LP00701, SD 169/, TRA0047574, NCGC00162142-01, NCGC00162142-02, NCGC00162142-03, NCGC00261386-01, AJ-64416, AN-49655, AS-16234, SMR001456333, KB-157690, LS-193646, FT-0670336, ST24038286, L-2207, 670I877, J-504708, BRD-K91904471-001-01-6

ID: 2919

chemical graph of compound 2919



InChIKey: GRQULPVAWRWZBM-UHFFFAOYSA-N
SMILES: O(C(=O)C)C1C=C(CBr)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2920

chemical graph of compound 2920



InChIKey: GXZRBVKDLNXVJG-UHFFFAOYSA-N
SMILES: C1=CC=CC(C(=O)CC)=C1OC(=O)C1=CC=C(C(F)(F)F)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2921

chemical graph of compound 2921



InChIKey: GYCFACVXYWODRE-UHFFFAOYSA-N
SMILES: C1(=CC=CS1)C(=O)OC1=C(C(=O)C)C(OC(=O)C2=CC=CS2)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2922

chemical graph of compound 2922



InChIKey: GYKFXFYRHJPFGH-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2923

chemical graph of compound 2923



InChIKey: HEMNVSCJOZIBEQ-UHFFFAOYSA-N
SMILES: C1=CNC(=C1)C(=O)C2=C(C=CC(=C2)Cl)NC(=O)CN

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 284708
synonyms found at PubChem are:
NSC140873, MLS000766105, 106410-13-3, NSC-140873, 2-amino-N-[4-chloro-2-(1H-pyrrole-2-carbonyl)phenyl]acetamide, Acetamide, 2-amino-N-[4-chloro-2-(1H-pyrrol-2-ylcarbonyl)phenyl]-, GCPK, 2-Amino-N-(4-chloro-2-(1H-pyrrole-2-carbonyl)phenyl)acetamide, ACMC-20ma4y, AC1L61GU, NCIStruc1_000814, NCIStruc2_000850, SCHEMBL9851289, CHEMBL1450586, CTK0D7247, ZINC21557, DTXSID00301064, HEMNVSCJOZIBEQ-UHFFFAOYSA-N, CCG-38259, NCGC00014365, NCI140873, AKOS030563283, NCGC00014365-02, NCGC00014365-03, NCGC00014365-04, NCGC00097473-01, NCI60_000895, SMR000528603, MLS000766105-02, MLS000766105-03, 2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, 2-amino-N-(4-chloro-2-(1H-pyrrol-2-ylcarbonyl)phenyl)acetamide

ID: 2924

chemical graph of compound 2924



InChIKey: HNEMOUFEHWAYRN-UHFFFAOYSA-N
SMILES: C1(=C(O)C=CC=C1)C(=O)C(C)C(=O)C1=CC=C([NH0+]([OH0-])=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2925

chemical graph of compound 2925



InChIKey: HOGSBGKVQPTDKE-UHFFFAOYSA-N
SMILES: C1(=C(O)C=C(OC)C=C1)C(=O)CC(=O)C1=CC=C(F)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2926

chemical graph of compound 2926



InChIKey: HRCYEQFRHAXCRH-UHFFFAOYSA-N
SMILES: CN1C2=C(C=N1)C(=NC(=N2)NC3=CC(=CC=C3)Cl)NC4=CC(=CC=C4)Cl

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 223753
synonyms found at PubChem are:
NSC11668, MLS000737956, NSC-11668, 4-N,6-N-bis(3-chlorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine, AC1L5CSO, NCIStruc1_001174, NCIStruc2_000793, cid_223753, CHEMBL1335220, SCHEMBL13100664, BDBM32629, MolPort-003-594-732, N4,4-d]pyrimidine-4,6-diamine, NCI11668, ZINC1718486, CCG-36888, NCGC00013125, AKOS024255121, MCULE-2217239478, NCGC00013125-02, NCGC00096246-01, NCI60_000381, SMR000528106, N4,N6-bis(3-chlorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

ID: 2927

chemical graph of compound 2927



InChIKey: HVSJZGGHNBBISO-OVCLIPMQSA-N
SMILES: CC1=NN(C2=CC=CC=C2)C(=O)C1/C(/C)=N/NC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2928

chemical graph of compound 2928



InChIKey: HWVWNQHBXROLPA-UHFFFAOYSA-N
SMILES: C1(=C(OCCCC)C=CC=C1)C1C=C(CCl)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 14674316

ID: 2929

chemical graph of compound 2929



InChIKey: ILIVMFBUBOLGDH-OAHLLOKOSA-N
SMILES: c1cc2c(cc1C3(CC3)C(=O)N[C@@H]4CC(Oc5c4ccc(c5)F)(CF)CF)OC(O2)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301346
synonyms found at PubChem are:
SCHEMBL17709038

ID: 2930

chemical graph of compound 2930



InChIKey: ILYSXJKVFYLRJF-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3C=CC(OC)=CC=3)C(CC3=CC=C(OC)C=C3)C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2931

chemical graph of compound 2931



InChIKey: IMMGMIGOJWHQPN-UHFFFAOYSA-N
SMILES: C1(=CC=CC=C1OC(=O)C1=CC=C(OC)C=C1)C(CC)=O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2932

chemical graph of compound 2932



InChIKey: INVTYAOGFAGBOE-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"EJ Sorscher" "J Matteson" "T Okiyoneda" "GL Lukacs" "WR Skach" "RA Frizzell" "Y Matsumura" "W Kellner" "B Hoch" "JR_3rd Yates" "WE Balch" "AP Rodrigues" "D Herman" "DM Hutt" "S Noel" "PJ Thomas" "M Gentzsch" "JM Pilewski" "A Schmidt" "G Manning" "JM Gottesfeld" "JR Riordan" "JW Kelly"


CID is 4261
synonyms found at PubChem are:
Entinostat, ms-275, 209783-80-2, SNDX-275, MS 275, MS-27-275, SNDX 275, MS 27-275, Histone Deacetylase Inhibitor I, Entinostat (USAN/INN), Entinostat (MS-275), UNII-1ZNY4FKK9H, 1ZNY4FKK9H, CHEMBL27759, pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate, pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate, INVTYAOGFAGBOE-UHFFFAOYSA-N, MS275, N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate, Entinostat (MS-275,SNDX-275), IN1470, NSC706995, BAY86-5274, NSC-706995, BAY 86-5274, pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate, pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate, 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate, Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester, W-201831, 3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide, pyridin-3-ylmethyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate, Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester, N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester, 442532-99-2, entinostatum, pyridin-3-ylmethyl (4-((2-aminophenyl)carbamoyl)benzyl)carbamate, N-(2-aminophenyl)-4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzamide, 3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, PubChem24433, AC1L1HRM, AC1Q5NOI, Entinostat [USAN:INN], MS-275 (Entinostat), MS-275 - Entinostat, D0M8FD, benzamide-type inhibitor, 3, MLS006010183, SCHEMBL148309, GTPL7007, DTXSID0041068, BDBM19410, CTK8F0220, AOB2570, EX-A038, SYN3039, CHEBI:132082, MolPort-005-942-713, BCPP000155, HMS3648K12, HMS3654O11, ACT06782, BCP01824, MS-275,Entinostat,SNDX-275/, ZINC1488870, ABP000145, BN0881, GP3697, s1053, AKOS024262667, AC-8968, AN-1299, BCP9000967, Carbamic acid, 3-pyridinylmethyl ester, CCG-208680, CS-0511, DB11841, Entinostat (MS-275, SNDX-275), RL02591, KS-0000063I, NCGC00165833-01, NCGC00165833-02, NCGC00165833-03, NCGC00165833-04, NCGC00165833-13, AJ-26331, AK158952, AS-17906, BC654076, HY-12163, KB-55107, MS27-275, NCI60_038022, SMR004458705, MS-275, A HDAC1 and HDAC3 inhibitor, AB0021206, AX8140473, KB-302728, LS-185285, RT-013958, ST2406823, FT-0667871, V2451, D09338, W-5370, 48247-EP2298768A1, 48247-EP2305643A1, 48247-EP2308868A1, 48247-EP2311494A1, 48247-EP2311840A1, 783M802, A815057, MS-275,Entinostat, SNDX-275, MS-27-275, SR-01000946382, Entinostat, SNDX-275, MS-27-275, MS-275, SR-01000946382-1, BRD-K77908580-001-02-1, BRD-K77908580-001-04-7, (pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate, [4-(2-Amino-phenylcarbamoyl)-benzyl]-carbamic acid pyridin-3-ylmethyl ester, N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]-3-pyridinylmethyl ester, carbamic acid, Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester

ID: 2933

chemical graph of compound 2933



InChIKey: IOEFAGPRYUOIGM-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC(C)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2934

chemical graph of compound 2934



InChIKey: IPGCPQVGKGPJDW-UHFFFAOYSA-N
SMILES: C1=CC=C2C=C(C=CC2=C1)C3=C(C=CC4=C3C(=O)C5=CC=CC=C5C4=O)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 222760
synonyms found at PubChem are:
NSC9608, NSC-9608, NCIStruc1_001012, NCIStruc2_000716, AC1L5C23, SCHEMBL5022959, CHEMBL1399619, CTK7I8558, NCI9608, ZINC3953831, CCG-36883, NCGC00013098, NCGC00013098-02, NCGC00096220-01, NCI60_042143, 1-naphthalen-2-yl-9,10-dioxoanthracene-2-carboxylic acid, 1-(naphthalen-2-yl)-9,10-dihydroanthracene-2-carboxylic acid, 1-(2-naphthyl)-9,10-dioxo-9,10-dihydro-2-anthracenecarboxylic acid, 1-(naphthalen-2-yl)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

ID: 2935

chemical graph of compound 2935



InChIKey: ISSNGBUFJXTJKY-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC=C2O)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2936

chemical graph of compound 2936



InChIKey: ITVSXBHQYQATBY-UHFFFAOYSA-N
SMILES: C1=CC=CC(C(=O)CC)=C1OC(=O)C1=C(F)C=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2937

chemical graph of compound 2937



InChIKey: IVGGOMCOSDERTG-UHFFFAOYSA-M
SMILES: [BrH0-].N(C)1C2C=CC=CC=2N2C(C3=CC=CC=C3)=[NH0+]3C4C=CC=CC=4N(C)C3=NC12

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2938

chemical graph of compound 2938



InChIKey: JAESBJYPWJXREU-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=O)OC2=CC(OC(=C)C3=CC(F)=CC=C3)=C(C(=O)C)C=C2)C=C1F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2939

chemical graph of compound 2939



InChIKey: JILWFSLORAUHMR-HNNXBMFYSA-N
SMILES: CC1(C[C@@H](c2cc(ccc2O1)F)NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301303
synonyms found at PubChem are:
SCHEMBL17708991

ID: 2940

chemical graph of compound 2940



InChIKey: JNAHVYVRKWKWKQ-CYBMUJFWSA-N
SMILES: C[C@@]1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N

biological descriptors:

CFTR relevance: PARP inhibitor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Nucleus (Transcription)

reference list:

"CA Gray" "SM Anjos" "L Yan" "R Robert" "KA Teske" "J Liao" "JW Hanrahan" "GW Carlile" "HM Sampson" "RJ Andersen" "DY Thomas" "RA Keyzers" "RG Linington" "D Zhang" "DE Williams" "RM Centko"
"D Waller" "J Goepp" "SM Anjos" "F Ciciriello" "R Phillipe" "R Robert" "J Liao" "F Dantzer" "JW Hanrahan" "DL Zhang" "GW Carlile" "HM Sampson" "DY Thomas" "P Ferraro" "H Balghi" "P Lesimple"


CID is 11960529
synonyms found at PubChem are:
Veliparib, 912444-00-9, ABT-888, ABT 888, Veliparib (ABT-888), ABT-888 (Veliparib), ABT888, UNII-01O4K0631N, 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide, CHEBI:62880, 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide, (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide, 01O4K0631N, 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-, Veliparib dihydrochloride, 2-((2r)-2-methyl-2-pyrrolidinyl)-1h-benzimidazole-7-carboxamide, (2r)-2-(7-Carbamoyl-1h-Benzimidazol-2-Yl)-2-Methylpyrrolidinium, (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-7-carboxamide, 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide, ABT-888(Veliparib), NSC-737664, Veliparib [USAN:INN], 2-((2R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide, 2-[(2R)-2-methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide, 78P, ABT-888 Veliparib, ABT888 (free base), D0Q7UD, A861695, benzimidazole carboxamide, 3a, MLS006010184, Veliparib (JAN/USAN/INN), SCHEMBL422318, CHEMBL506871, GTPL7417, QCR-33, BDBM27135, ABT-695, DTXSID90238456, EX-A001, MolPort-016-633-168, BDBM209932, AOB87114, EBD52357, 1H-Benzimidazole-7-carboxamide, 2-[(2R)-2-methyl-2-pyrrolidinyl]-, ABP000419, AN-034, BN0721, IN2264, NSC737664, s1004, ZINC84610155, AKOS015951440, AKOS017343746, API0024782, CS-0076, DB07232, EX-7209, RL05736, ABT-888(Veliparib)/MX-1,ABT888, NCGC00250404-01, AC-23330, AN-26402, AS-19397, BC623040, EN002695, HY-10129, KB-67929, SMR004701290, ABT-888 (Veliparib, NSC 737664), AB1010175, FT-0660949, X7540, A24888, D09692, W-5661, A-861695, J-505211, BRD-K87142802-001-02-7, Veliparib;ABT-888;ABT888;ABT 888;912444-00-9, 1H-Benzimidazole-4-carboxamide, 2-((2R)-2-methyl-2-pyrrolidinyl)-, 2-[(2R)-2-methylpyrrolidin-2-yl]-3H-1,3-benzodiazole-4-carboxamide, (R)-2-(2-Methylpyrrolidin-2-yl)-1H-benimidazole-4-carboxamide (VELIPARIB), ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide;(R)-2-(2-methylpyrrolidin-2-yl)-3H-benzo[d]imidazole-4-carboxamide

ID: 2941

chemical graph of compound 2941



InChIKey: JQFYWDFHYYBWDL-UHFFFAOYSA-N
SMILES: C1(=C(O)C=CC=C1)C(=O)C(C)C(=O)C1=C(F)C=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2942

chemical graph of compound 2942



InChIKey: JSMKCCIMZBFWNW-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CC2=C(C=CC(=C2)NC3=C4C=C(C=CC4=[NH+]C5=C3C=CC(=C5)Cl)OC)O.[Cl-]

biological descriptors:

CFTR relevance: CFTR corrector, pocket 1

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"EL Saussereau" "D Tondelier" "N Servel" "F Becq" "J Fritsch" "M Dadlez" "G Faure" "GL Lukacs" "MF da Cunha" "K Tarnowski" "M Ollero" "A Kupniewska" "S Bitam" "N Odolczyk" "L Wiszniewski" "C Norez" "P Zielenkiewicz" "J Colas" "H Herrmann" "A Edelman" "P Melin-Heschel" "A Roldan" "G Wieczorek"


CID is 5458251
synonyms found at PubChem are:
NSC130813, AC1NUQ41, DTXSID60419997, Phenol, 4-[(6-chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-, 4-[(6-chloro-2-methoxyacridin-10-ium-9-yl)amino]-2-[(4-methylpiperazin-1-yl)methyl]phenol chloride, CHEMBL1970271, 4-(6-chloro-2-methoxyacridin-9-ylamino)-2-((4-methylpiperazin-1-yl)methyl)phenol, dihydrochloride

ID: 2943

chemical graph of compound 2943



InChIKey: JTDYUFSDZATMKU-UHFFFAOYSA-N
SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"EJ Sorscher" "J Matteson" "T Okiyoneda" "GL Lukacs" "WR Skach" "RA Frizzell" "Y Matsumura" "W Kellner" "B Hoch" "JR_3rd Yates" "WE Balch" "AP Rodrigues" "D Herman" "DM Hutt" "S Noel" "PJ Thomas" "M Gentzsch" "JM Pilewski" "A Schmidt" "G Manning" "JM Gottesfeld" "JR Riordan" "JW Kelly"


CID is 5186
synonyms found at PubChem are:
scriptaid, 287383-59-9, Scriptide, 6-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-hydroxyhexanamide, GCK 1026, GNF-PF-2024, CGK1026, IN1099, 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexanoic acid hydroxyamide, CHEMBL96051, SB-556629, 6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide, JTDYUFSDZATMKU-UHFFFAOYSA-N, N-Hydroxy-1,3-dioxo-1H-benz(de)isoquinoline-2(3H)-hexan amide, N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide, Scriptaid(GCK1026), AC1L1JSF, scriptaid and CGK1026, D0J8OC, AC1Q6JL7, CBDivE_004422, Scriptaid, >=95%, solid, SCHEMBL780490, SCHEMBL780491, GTPL7505, CHEBI:92401, CTK8A6808, KS-00002WSH, DTXSID70274458, MolPort-000-434-144, HMS3269C11, HMS3653D06, 1h-benz[de]isoquinoline-2(3h)-hexanamide, n-hydroxy-1,3-dioxo-, BCP06506, CGK-1026, EX-A1108, ZINC3873638, ANW-62572, BDBM50328678, s8043, SBB039068, STL259803, AKOS000267387, CCG-208690, CS-1014, EG-0074, MCULE-6788459337, QC-8209, NCGC00159564-01, AJ-46378, BAS 00383114, BC600420, HY-15489, AB0097168, AX8233431, KB-144449, RT-015680, FT-0674544, ST45174702, SJ000016636, W-5105, AB00075588-01, SR-01000398526, J-017229, SR-01000398526-1, BRD-K22503835-001-03-7, BRD-K22503835-001-05-2, I14-11722, N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexananmide, 6-(1,3-Dioxo-1H, 3H-benzo[de]isoquinolin-2-yl)-hexanoic acid hydroxyamide, 6-(1,3-DIOXO-1H,3H-BENZO[DE]ISOQUINOLIN-2-YL)-N-HYDROXYHEXANAMIDE

ID: 2944

chemical graph of compound 2944



InChIKey: JVNIIBYLOWNHTF-UHFFFAOYSA-N
SMILES: O(CCC1ON=C(C2SC=CC=2)C=1)CC1=CC(C2C=C(COCCCC)ON=2)=NO1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2945

chemical graph of compound 2945



InChIKey: JWUWDIDAEMXJGS-UHFFFAOYSA-N
SMILES: C1(=C(OCC2=CC=C(OC)C=C2)C=CC=C1)C(=O)CC(=O)C1=CC=C(F)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2946

chemical graph of compound 2946



InChIKey: KBGSVTREQRCYHG-UHFFFAOYSA-N
SMILES: C2(=CC=C1C=C(C(=NC1=C2)N3CCN(CCC3)C(C4=CC=CS4)=O)C#N)C.CC

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"MJ Kurth" "AB Wood" "PW Phuan" "GL Lukacs" "JM Knapp" "AS Verkman" "B Yang"


ID: 2947

chemical graph of compound 2947



InChIKey: KCSNPRILQSVFOU-UHFFFAOYSA-N
SMILES: C1=CC=CC(C(=O)CC)=C1OC(=O)C1=C(C(F)(F)F)C=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2948

chemical graph of compound 2948



InChIKey: KDOQEEMQPHIANX-NFBKMPQASA-N
SMILES: COc1ccc2c(c1)O[C@H](C[C@H]2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6ccc(c(c6)OC)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301295
synonyms found at PubChem are:
SCHEMBL17708983

ID: 2949

chemical graph of compound 2949



InChIKey: KDOQEEMQPHIANX-REWPJTCUSA-N
SMILES: COc1ccc2c(c1)O[C@@H](C[C@@H]2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6ccc(c(c6)OC)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301422
synonyms found at PubChem are:
SCHEMBL17709121

ID: 2950

chemical graph of compound 2950



InChIKey: KDOQEEMQPHIANX-UHFFFAOYSA-N
SMILES: COc1ccc2c(c1)OC(CC2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6ccc(c(c6)OC)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301071
synonyms found at PubChem are:
SCHEMBL17708738

ID: 2951

chemical graph of compound 2951



InChIKey: KDPLWCIHSTZJEV-UHFFFAOYSA-N
SMILES: C1(=CC=CC(I)=C1)C(=O)OC1=C(C(=O)C)C(OC(C2=CC(I)=CC=C2)=O)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2952

chemical graph of compound 2952



InChIKey: KITUSBSMWKXNRB-UHFFFAOYSA-N
SMILES: C1(=CC=C(C(=O)OC2=CC(OC(=C)C3=CC=C(OC)C=C3)=C(C(=O)C)C=C2)C=C1)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2953

chemical graph of compound 2953



InChIKey: KOSYICZFSFHGCD-UHFFFAOYSA-N
SMILES: C(C1=C(C)C=CS1)1C(C(=O)OC2=CC=CC=C2)=C(C)NC(C)=C1C(=O)OCC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "F Cateni" "N Pedemonte" "LJ Galietta" "M Giampieri" "M Mazzei" "MT Mazzei" "M Zacchigna"


ID: 2954

chemical graph of compound 2954



InChIKey: KQGDQANXUPFIIA-UHFFFAOYSA-N
SMILES: C1=CC=CC=C1C(=O)NNC(C)CC(=O)OCC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2955

chemical graph of compound 2955



InChIKey: KWNVHMCTCWXXLZ-TZIWHRDSSA-N
SMILES: c1cc(cc(c1)C(=O)O)[C@H]2C[C@H](c3ccc(cc3O2)OC(F)F)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301330
synonyms found at PubChem are:
SCHEMBL17709022, KWNVHMCTCWXXLZ-TZIWHRDSSA-N, 3-((2R,4R)-4-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-7-(difluoromethoxy)chroman-2-yl)benzoic acid

ID: 2956

chemical graph of compound 2956



InChIKey: KXTYBXCEQOANSX-MQYZIMMHSA-N
SMILES: C[C@@H]1[C@H]\2CC[C@H](/C2=C/[C@]3([C@@H](CC(=C3[C@@H]([C@H]1O)O[C@@H]4[C@H]([C@@H]([C@H]([C@@H](O4)COC(C)(C)C=C)O)OC(=O)C)O)[C@H](C)COC(=O)C)O)C)COC

biological descriptors:

CFTR relevance: selective interaction with CFTR secondary binding motif (pS753)

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment several

reference list:

"GW Carlile" "DS van Scheppingen" "DY Thomas" "C Ottmann" "LM Stevers" "L Brunsveld" "FA Meijer" "LG Milroy" "CV Lam" "SF Leysen" "RM de Vries"


CID is 46936214
synonyms found at PubChem are:
20108-30-9, SCHEMBL158595

ID: 2957

chemical graph of compound 2957



InChIKey: KXZVPHGDSJNZRR-IFRROFPPSA-N
SMILES: CC1=CC=C(NCC(N/N=C/C2=C(O)C(Br)=C(O)C(Br)=C2)=O)C=C1

biological descriptors:

CFTR relevance: CFTR inhibitor/ potentiator

Category:
Influence on CFTR function inconsistent assignment
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"H Senderowitz" "N Khazanov" "BR Imhoff" "NA McCarty" "G Cui" "DT Infield" "BB Stauffer"


ID: 2958

chemical graph of compound 2958



InChIKey: LAQHMYWBDXANEB-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3=CC=C(C(C)(C)C)C=C3)C([HH0])C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2959

chemical graph of compound 2959



InChIKey: LDBZGWZLNWRWQR-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3C=CC=CC=3)C(CC3=CC=C(OC)C=C3)C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2960

chemical graph of compound 2960



InChIKey: LJBFRHUDVJSADK-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C(O)=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2961

chemical graph of compound 2961



InChIKey: LJRKZRPXQQKVHM-UHFFFAOYSA-N
SMILES: C1(=CC=C(Br)C=C1)C(=O)OC1=C(C(=O)C)C(OC(C2=CC=C(Br)C=C2)=O)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2962

chemical graph of compound 2962



InChIKey: LOZMSKIOLRIOMA-UHFFFAOYSA-N
SMILES: C1C2OC(C3C=CC(O)=CC=3)=CC(=O)C=2C(OC)=C(O)C=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 45359983

ID: 2963

chemical graph of compound 2963



InChIKey: LPMXVESGRSUGHW-HBYQJFLCSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"A Luini" "JW Hanrahan" "GW Carlile" "SM Anjos" "F Ciciriello" "DY Thomas" "D Zhang" "A Carissimo" "H Balghi" "R Robert" "J Liao"


CID is 439501
synonyms found at PubChem are:
ouabain, G-Strophanthin, Ouabaine, Astrobain, Gratibain, Purostrophan, Strodival, Oubain, Ouabagenin L-rhamnoside, Ouabain anhydrous, Kombetin, Uabanin, Ouabagenin-L-rhamnosid, 630-60-4, Acocantherin, Ouabain octahydrate, Acocantherine, Quabain, Strophanthin-G, Strophalen, Uabaina, Gratus strophanthin, Ouabain, Octahydrate, Rectobaina, Solufantina, Strophoperm, Strophosan, G-Strophicor, UNII-5ACL011P69, Ouabagenin-L-rhamnosid [German], CHEBI:472805, G-Strophanthin (JAN), Strophanthin G, MLS000069786, CHEMBL222863, LPMXVESGRSUGHW-HBYQJFLCSA-N, 5ACL011P69, Acolongifloroside K, SMR000058492, O 3125, DSSTox_CID_23765, DSSTox_RID_80072, DSSTox_GSID_43765, 3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, Card-20(22)-enolide, 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, (1.beta.,3.beta.,5.beta.,11.alpha.)-, CCRIS 965, OBN, HSDB 3519, EINECS 211-139-3, Ouabain (anhydrous), NSC 25485, NSC-25485, BRN 0101712, CAS-630-60-4, SR-01000076047, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11,14,19-pentahydroxy-, (1beta,3beta,5beta,11alpha)-, Cardiac glycoside, 1ibg, 3-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11alpha,14,19-pentahydroxycard-20(22)-enolide, 3-(6-Deoxy-alpha-L-mannopyranosyloxy)-1,5,11a,14,19-pentahydroxycard-20(22)-enolide, NCGC00163473-01, 3a3y, Opera_ID_395, 4-[5-((6S,2R,3R,4R,5R)-3,4,5-trihydroxy-6-methyl(2H-3,4,5,6-tetrahydropyran-2- yloxy))(1S,5S,7S,11S,2R,3R,10R,14R,15R,17R)-3,7,11,17-tetrahydroxy-2-(hydroxym ethyl)-15-methyltetracyclo[8.7.0.0<2,7>.0<, Prestwick0_000471, Prestwick1_000471, Prestwick2_000471, Prestwick3_000471, D0AR3J, Epitope ID:161502, Lopac0_000943, SCHEMBL15433, BSPBio_000602, 5-18-05-00625 (Beilstein Handbook Reference), SPBio_002541, AC1L97H2, BPBio1_000664, cid_439501, GTPL4826, DTXSID0043765, REGID_for_CID_439501, 3n23, HMS2089J19, HMS2235A07, HMS3262N08, ZINC8143614, Tox21_110024, Tox21_112057, Tox21_301547, Tox21_500943, BDBM50286739, AKOS024285581, Tox21_112057_1, CCG-205024, CCG-208243, DB01092, LP00943, SMP1_000142, NCGC00013319-01, NCGC00017394-02, NCGC00017394-07, NCGC00017394-11, NCGC00255970-01, NCGC00261628-01, NCGC00263656-01, ST085767, TL8004371, EU-0100943, C01443, D00112, 11,15>]heptadec-14-yl]-5-hydrofuran- 2-one, SR-01000721848, SR-01000076047-1, SR-01000076047-5, SR-01000721848-2, SR-01000721848-4, BRD-K35708212-331-03-1, I14-91595, dro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide, 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahy, 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one, 3-[(6-Deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11.alpha.,14,19-pentahydroxycard-20(22)-enolide, 36-06-6, 4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one, 4-((1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one, 4-((1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one, 4-((1R,3S,5S,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one, 4-[(1R,3S,5S,10R,11R,13R,14S,17R)-1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-methyl-3-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one, 4-[(1S,2R,3R,5S,7S,10R,11S,14R,15R,17R)-3,7,11,17-tetrahydroxy-2-(hydroxymethyl)-15-methyl-5-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one, 4-[(1S,2R,3R,5S,7S,10R,11S,14R,15R,17R)-3,7,11,17-tetrahydroxy-2-(hydroxymethyl)-15-methyl-5-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one, 4-[(R)-1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-methyl-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one, 4-[1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-methyl-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one, 4-[1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-methyl-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one(Ouabain), Ouabain4-[1,5,11,14-Tetrahydroxy-10-hydroxymethyl-13-methyl-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one

ID: 2964

chemical graph of compound 2964



InChIKey: LSBRKYXIZOVMPC-IFMALSPDSA-N
SMILES: COc1ccc2c(c1)O[C@H](C[C@H]2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6cccc(c6)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301099
synonyms found at PubChem are:
SCHEMBL17708770

ID: 2965

chemical graph of compound 2965



InChIKey: LZXFUJLBNMWMTG-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C(C)(C)C)C(CC3=CC=C(OC)C=C3)C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2966

chemical graph of compound 2966



InChIKey: MEIWPWUOEABHDN-UHFFFAOYSA-N
SMILES: C1C2C(CC3C=CC(OC)=CC=3)C(C3=CC=C(OC)C=C3)=CC(=S)C=2C=CC=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2967

chemical graph of compound 2967



InChIKey: MFNQKAIAXLFNSY-UHFFFAOYSA-N
SMILES: C(C1=C(SCC(=C)OC)C=CS1)1C(C(=O)OC=C)=C(C)NC(C)=C1C(=O)OCC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "F Cateni" "N Pedemonte" "LJ Galietta" "M Giampieri" "M Mazzei" "MT Mazzei" "M Zacchigna"


ID: 2968

chemical graph of compound 2968



InChIKey: MGASRLPRYQFEOV-UHFFFAOYSA-N
SMILES: C1=CC(OC)=C(OC)C=C1C1CC(C2=C(O)C=CC=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2969

chemical graph of compound 2969



InChIKey: MMWQJOSBRVMGOI-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)C(CC(O2)c3ccc(cc3)F)NC(=O)C4(CC4)c5ccc6c(c5)OC(O6)(F)F

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301441
synonyms found at PubChem are:
SCHEMBL17709144

ID: 2970

chemical graph of compound 2970



InChIKey: MSJZLLIPXKKZGX-UHFFFAOYSA-N
SMILES: C1(=NC=CC=C1)C1C=C(CCCCO)ON=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2971

chemical graph of compound 2971



InChIKey: MVMMUALTIFMQMK-IFRROFPPSA-N
SMILES: CC1=CC=CC(NCC(N/N=C/C2=C(O)C(Br)=C(O)C(Br)=C2)=O)=C1

biological descriptors:

CFTR relevance: CFTR inhibitor/ potentiator

Category:
Influence on CFTR function inconsistent assignment
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"H Senderowitz" "N Khazanov" "BR Imhoff" "NA McCarty" "G Cui" "DT Infield" "BB Stauffer"


ID: 2972

chemical graph of compound 2972



InChIKey: MVOGWHHKDLPIRK-UHFFFAOYSA-N
SMILES: C([HH0])1C(CCCC=C)=NN(C)C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2973

chemical graph of compound 2973



InChIKey: MXKWAONIBDUVHH-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3=CC=CC=C3)C(C)C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2974

chemical graph of compound 2974



InChIKey: NAHUFJFDQUVAKK-UHFFFAOYSA-N
SMILES: C1=C(OC)C(OC)=CC2C(=O)C=C(C3=CC=CC=C3)C([HH0])C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2975

chemical graph of compound 2975



InChIKey: NBOUPBHKHJTNRN-UHFFFAOYSA-N
SMILES: C12C3=NOC=C3CCC1=NN(C1=CC=CC=C1)C2OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2976

chemical graph of compound 2976



InChIKey: NGBOHPTYWQLVMV-UHFFFAOYSA-N
SMILES: C1(=CC=NC=C1)C(=O)OC1=C(C(=O)C)C(OC(C2=CC=NC=C2)=O)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2977

chemical graph of compound 2977



InChIKey: NOGRVEQYQUCZIW-UHFFFAOYSA-N
SMILES: C2=C(C=C1C=C(C(=NC1=C2)N3CCN(CC3)C(C4=CC=CC=C4F)=O)C#N)OC.CC

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"MJ Kurth" "AB Wood" "PW Phuan" "GL Lukacs" "JM Knapp" "AS Verkman" "B Yang"


ID: 2978

chemical graph of compound 2978



InChIKey: NRWHTHBUNDPHEF-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC(Cl)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2979

chemical graph of compound 2979



InChIKey: NTGHLTJGUCFIPS-UHFFFAOYSA-N
SMILES: C1=CC(OC)=CC(OC)=C1C1CC(C2=C(O)C=CC(C)=C2)=NN1C1=CC=C(S(N)(=O)=O)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"HK Lee" "DK Jeon" "Y Seo" "W Namkung" "J Park" "PK Sharma" "S Jo" "P Khloya" "S Kumar"


ID: 2980

chemical graph of compound 2980



InChIKey: NVRPGIJDVFYITJ-UHFFFAOYSA-N
SMILES: C1(=C(OCC2=CC=C(OC)C=C2)C=CC=C1)C(=O)CC(=O)C1=CC(F)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2981

chemical graph of compound 2981



InChIKey: NYGSCGZLRDWSCH-OAHLLOKOSA-N
SMILES: CC1(C[C@H](c2ccc(cc2O1)F)NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301017
synonyms found at PubChem are:
SCHEMBL17708679

ID: 2982

chemical graph of compound 2982



InChIKey: OBDBYTRXBRUTCB-UHFFFAOYSA-N
SMILES: C1(=CC=C(I)C=C1)C(=O)OC1=C(C(=O)C)C(OC(C2=CC=C(I)C=C2)=O)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2983

chemical graph of compound 2983



InChIKey: OFOBYRCVWRMUBR-CQSZACIVSA-N
SMILES: CC1(C[C@H](c2ccc(c(c2O1)Cl)F)NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301090
synonyms found at PubChem are:
SCHEMBL17708759

ID: 2984

chemical graph of compound 2984



InChIKey: OGSFIMJSKBBFSW-GZTJUZNOSA-N
SMILES: C(/C=N/O)1C(C2=CC=CC=C2)=NN(C2=CC=CC=C2)C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2985

chemical graph of compound 2985



InChIKey: OOTDVWYTCGAGSF-UHFFFAOYSA-M
SMILES: [NH0+](C(C1=CC=CC=C1)CO)1C=CC(C2=CC=CC=C2)=CC=1.[ClH0-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 15032068

ID: 2986

chemical graph of compound 2986



InChIKey: OTBDHKHVNBQWFV-UHFFFAOYSA-N
SMILES: C1(=CC([NH0+](=O)[OH0-])=CC([NH0+](=O)[OH0-])=C1)C(=O)OC1=C(C(=O)C)C(OC(C2=CC([NH0+](=O)[OH0-])=CC([NH0+]([OH0-])=O)=C2)=O)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2987

chemical graph of compound 2987



InChIKey: OWFSTCAGKNYXRG-OVCLIPMQSA-N
SMILES: C(/C(=N/NC(N)=S)/C)1C(C)=NN(C2=CC=CC=C2)C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2988

chemical graph of compound 2988



InChIKey: OYXCBBGZDQAGIJ-UHFFFAOYSA-N
SMILES: C1=CC=CC2C(=O)C=C(C3=CC=CC=C3F)C([HH0])C1=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2989

chemical graph of compound 2989



InChIKey: PEZMUBLXTZBCNH-UHFFFAOYSA-N
SMILES: COc1ccc2c(c1)OC(CC2NC(=O)C3(CC3)c4ccc5c(c4)OC(O5)(F)F)c6ccccc6

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown


CID is 121301272
synonyms found at PubChem are:
SCHEMBL17708957, PEZMUBLXTZBCNH-UHFFFAOYSA-N, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(7-methoxy-2-phenyl-3,4-dihydro-2H-chromen-4-yl)cyclopropanecarboxamide

ID: 2990

chemical graph of compound 2990



InChIKey: PFHMJXYLDFULMN-UHFFFAOYSA-N
SMILES: C1(=C(OCC2=CC=C(OC)C=C2)C=C(OC)C=C1)C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2991

chemical graph of compound 2991



InChIKey: PIQXRWPBEVAGHI-UHFFFAOYSA-N
SMILES: C1(=C(O)C=CC=C1)C(=O)C(C)C(=O)C1=CC=C(Br)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2992

chemical graph of compound 2992



InChIKey: PKSAVTDUQSLZSC-UHFFFAOYSA-N
SMILES: C1C2OC(C3C=CC(C4=CC(N)=CC=C4)=CC=3)=CC(=O)C=2C(O)=CC=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2993

chemical graph of compound 2993



InChIKey: PLVMNQFZAPDHTE-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=O)OC2=CC(OC(=C)C3=CC=CC=C3I)=C(C(=O)C)C=C2)C(I)=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2994

chemical graph of compound 2994



InChIKey: PMAIUMUDXRAWIA-RIYZIHGNSA-N
SMILES: CN/N=C/C1=CC=C(O1)C2=CC=C(C=C2)[N+](=O)[O-]

biological descriptors:

CFTR relevance: no effect

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"JW Hanrahan" "GW Carlile" "HM Sampson" "E Matthes" "DY Thomas" "R Robert" "J Liao"


CID is 5899356
synonyms found at PubChem are:
AC1NZ3F4, CCG-683, MolPort-002-912-560, N-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]methanamine

ID: 2995

chemical graph of compound 2995



InChIKey: PSPRNONTFBJUDQ-SCFUHWHPSA-N
SMILES: O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]4O[C@@H](n2cnc1c(ncnc12)NCCc3ccccc3)[C@H](O)[C@@H]4O

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"H Miki" "M Li" "SG Bompadre" "TC Hwang" "Z Zhou"


CID is 11505398
synonyms found at PubChem are:
n6-(2-phenylethyl)adenosine-5'-O-triphosphate, N-(2-Phenylethyl)adenosine 5'-(Tetrahydrogen Triphosphate), B44

ID: 2996

chemical graph of compound 2996



InChIKey: PSTBVOOOXULDDA-UHFFFAOYSA-N
SMILES: C1(=C(O)C=CC=C1)C(=O)C(C)C(=O)C1=CC(F)=CC=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2997

chemical graph of compound 2997



InChIKey: PTGJZUROQFKRIW-UHFFFAOYSA-N
SMILES: C([HH0])1C(CCCC=C)=NN(C2=CC=CC=C2)C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


ID: 2998

chemical graph of compound 2998



InChIKey: PVGXJMXLVGVBKO-JNSGDMPLSA-N
SMILES: N(CCC(F)C)1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1

biological descriptors:

CFTR relevance: Non-effective CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"J Désiré" "A Mingot" "S Thibaudeau" "F Becq" "Y Blériot" "V Cendret" "A Kato" "M Forcella" "I Adachi" "C Norez" "T Legigan" "P Parenti" "J Bertrand"


ID: 2999

chemical graph of compound 2999



InChIKey: QIQCNQCWHDCIQD-UHFFFAOYSA-M
SMILES: [IH0-].C12C=CC(Cl)=CN1C[NH0+]1C=C(Cl)C=CC=1N=2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"


CID is 15476027

ID: 3000

chemical graph of compound 3000



InChIKey: QQCLEZZIXKKGQV-UHFFFAOYSA-N
SMILES: C(C(=O)CC)1=CC=CC=C1OC(=O)C1=CC=C(Br)C=C1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "MF Springsteel" "EJ Niedzinski" "LJ Galietta" "MH Nantz" "AS Verkman" "M Eda" "MJ Haddadin" "K By"