CandActCFTR Seed Compounds

The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.

ID: 501

InChIKey: DPUYFRUJYACFFQ-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C3=C4C(=CC(=C13)OC)C(C(=O)C5=C(C=C(C(=C45)C2=O)OC)OC)(C)C)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4309556
synonyms found at PubChem are:
KBio2_002348, Spectrum_001843, Spectrum5_001816, AC1N7X0K, KBioSS_002351, KBio2_004916, KBio2_007484, RESISTOMYCIN, TETRAMETHYL ETHER

ID: 502

InChIKey: DPYIXBFZUMCMJM-BTJKTKAUSA-N
SMILES: CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6435335
synonyms found at PubChem are:
Flupirtine maleate, 75507-68-5, Katadolon, Flupirtine Maleate Salt, Flupirtine (Maleate), Flupirtin-maleat [German], UNII-0VCI53PK4A, Flupirtine maleate [USAN], W 2964M, EINECS 278-225-0, 0VCI53PK4A, D-9998, W-2964M, NCGC00093935-01, Ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate maleate (1:1), Ethyl-N-(2-amino-6-(4-fluorophenylmethylamino)pyridin-3-yl)carbamate maleate, Flupirtine maleate (USAN), (2-Amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)carbamic acid ethyl ester maleate, DSSTox_CID_25771, DSSTox_RID_81113, Ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino)pyridin-3-yl)carbamat maleat [German], DSSTox_GSID_45771, Q-101869, Flupirtin-maleat, 2-Amino-3-(ethoxycarbonylamino)-6-(4-fluorobenzylamino)pyridine Maleate Salt, ETHYL (2-AMINO-6-((4-FLUOROBENZYL)AMINO)PYRIDIN-3-YL)CARBAMATE MALEATE, Ethyl 2-amino-6-((4-fluorobenzyl)amino)pyridine-3-carbamate, compound with maleic acid (1:1), C19H21FN4O6, Carbamic acid, (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)-, ethyl ester, (Z)-2-butenedioate (1:1), CAS-75507-68-5, NCGC00015451-03, Flupirtinmaleat, D 9998, Effirma, (Z)-but-2-enedioic acid;ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate, Ethyl 2-amino-6-(4-fluorobenzylamino)pyridin-3-ylcarbamate maleate, FLUPIRITNE MALEATE, AC1O5JLR, flupirtine maleate (1:1), SCHEMBL124707, CHEMBL1256752, DTXSID8045771, DPYIXBFZUMCMJM-BTJKTKAUSA-N, MolPort-003-941-407, HMS3261N15, 56995-20-1 (Parent), 75507-68-5 (maleate)., C15H18N4O2.C4H4O4, Tox21_111232, Tox21_113397, Tox21_500547, ABP000440, AC-454, BG0448, Flupirtine maleate/D 9998,Katadolon, AKOS024286722, Ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino)pyridin-3-yl)carbamat maleat, Tox21_111232_1, AF10216, AN-1081, BCP9000699, CCG-221851, CS-0573, LP00547, RL04876, NCGC00015451-05, NCGC00093935-02, NCGC00261232-01, 133AP001, BC227821, HY-17001, LS-48933, ST096085, Flupirtine maleate salt, >=98% (HPLC), KB-297192, EU-0100547, F0736, D04226, F 8927, J10053, W-5234, 507F685, A838439, SR-01000075887, I06-1582, SR-01000075887-1, [2-AMINO-6-(4-FLUORO-BENZYLAMINO)-PYRIDIN-3-YL]-CARBAMIC ACID ETHYL ESTER MALEATE, 2-Amino-6-[(p-fluorobenzyl)amino]-3-pyridinecarbamic Acid Ethyl Ester Maleate, 2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid, ethyl ester maleate, ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridyl]carbamate; maleic acid, N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate, (Z)-but-2-enedioic acid; ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate, (Z)-but-2-enedioic acid; ethyl N-[2-azanyl-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate, [2-AMINO-6-[[(4-FLUOROPHENYL)METHYL]AMINO]-3-PYRIDINYL]-CARBAMIC ACID ETHYL ESTER MALEATE SALT, 2-AMINO-[6-[[(4-FLUOROPHENYL)METHYL]AMINO]]-3-PYRIDINYL-CARBAMIC ACID ETHYL ESTER MALEATE, 56995-21-2, Carbamic acid, (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)-, ethyl ester,(Z)-2-butenedioate (1:1), CARBAMIC ACID, N-[2-AMINO-6-[[(4-FLUOROPHENYL)METHYL]AMINO]-3-PYRIDINYL]-, ETHYL ESTER, (2Z)-2-BUTENEDIOATE (1:1), N-(2-amino-6-{[(4-fluorophenyl)methyl]amino}(3-pyridyl))ethoxycarboxamide, (2Z )but-2-enedioic acid, N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester; (Z)-2-butenedioic acid, N-[2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic Acid Ethyl Ester (2Z)-2-Butenedioate, N-[2-AMINO-6-[[[4-FLUOROPHENYL]METHYL]AMINO]-3-PYRIDINYL]CARBAMIC ACID ETHYL ESTER MALEATE

ID: 503

InChIKey: DQMZLTXERSFNPB-UHFFFAOYSA-N
SMILES: CCC1(C(=O)NCNC1=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4909
synonyms found at PubChem are:
primidone, 125-33-7, Primaclone, Mysoline, Lepimidin, Mylepsinum, Misodine, Mizodin, Mylepsin, Primidon, Sertan, 2-Deoxyphenobarbital, 2-Desoxyphenobarbital, Hexadiona, Lepsiral, Liskantin, Majsolin, Milepsin, Misolyne, Neurosyn, Prilepsin, Primakton, Primoline, Prysoline, Midone, Mizolin, Mysedon, Cyral, Medi-Pets, Primacone, Desoxyphenobarbitone, Pyrimidone Medi-pets, Primidonum, Primidona, Resimatil, Desoxyphenobarbital, Primacione, Roe 101, 5-Phenyl-5-ethyl-hexahydropyrimidine-4,6-dione, Myidone, 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl-, Apo-Primidone, Primidone (primaclone), 5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione, Primidonum [INN-Latin], Primidona [INN-Spanish], 5-ethyl-5-phenyldihydropyrimidine-4,6(1H,5H)-dione, NCI-C56360, Hexamidine (the antispasmodic), 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione, 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione, 5-Ethylhexahydro-4,6-dioxo-5-phenylpyrimidine, 5-Ethylhexahydro-5-phenylpyrimidine-4,6-dione, 4,4'-(Hexamethylenedioxy)dibenzamidine, Pms Primidone, CCRIS 54, NSC 41701, Mysoline (TN), 5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion, UNII-13AFD7670Q, HSDB 3169, Primidone [USAN:INN:BAN:JAN], EINECS 204-737-0, 5-Phenyl-5-aethylhexahydropyrimidindion-(4,6), Primidone Methanol Solution, BRN 0218034, Hexamidine(the antispasmodic), 5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion [German], 5-Phenyl-5-aethylhexahydropyrimidindion-(4,6) [German], MLS000028593, CHEBI:8412, DQMZLTXERSFNPB-UHFFFAOYSA-N, 13AFD7670Q, NCGC00015834-11, CAS-125-33-7, SMR000058501, DSSTox_CID_3510, P 7295, 5-ethylhe xahydro-4,6-dioxo-5-phenylpyrimidine, DSSTox_RID_77058, DSSTox_GSID_23510, 5-Ethyl-5-phenyldihydro-4,6(1H,5H)-pyrimidinedione, 5-ethyldihydro-5-phenyl-4,6[1H,5H]-pyrimidinedione, Primidon Holsten, SR-01000003162, 5-ethyl-5-phenyl-1,2,3,5-tetrahydropyrimidine-4,6-dione, Primidone [USP:INN:BAN:JAN], Mylepsinum (TN), Liskantin (TN), Prysoline (TN), Resimatil (TN), Primidone(Mysoline), Sertan (TN), Primidone (Mysoline), Apo-Primidone (TN), Spectrum_000832, Tocris-0830, Pyrimidone "Medi-pets", Pyrimidone 'Medi-pets', Pyrimidone (Medi-pets), Xcel Brand of Primidone, Astra Brand of Primidone, Opera_ID_1083, Prestwick0_000933, Prestwick1_000933, Prestwick2_000933, Prestwick3_000933, Spectrum2_001293, Spectrum3_000553, Spectrum4_000485, Spectrum5_001144, Lopac-P-7295, Apotex Brand of Primidone, Draxis Brand of Primidone, Zeneca Brand of Primidone, Mysoline;Neurosyn;Mylepsin, Biomol-NT_000261, CHEMBL856, D0U5RT, Desitin Brand of Primidone, Holsten Brand of Primidone, Pyrimidone ''Medi-pets'', Lopac0_001021, SCHEMBL34221, BSPBio_000866, BSPBio_002225, KBioGR_000969, KBioSS_001312, 5-24-08-00102 (Beilstein Handbook Reference), MLS001055411, MLS001074125, BIDD:GT0319, DivK1c_000324, Primidone, analytical standard, SPECTRUM1500501, AstraZeneca Brand of Primidone, SPBio_001325, SPBio_003035, Primidone (JP15/USP/INN), Primidone (JP17/USP/INN), AC1L1J82, BPBio1_000859, BPBio1_000954, GTPL5338, ZINC1979, hexamidine (the antispasmodic), DTXSID7023510, CTK8B3224, HMS501A06, KBio1_000324, KBio2_001312, KBio2_003880, KBio2_006448, KBio3_001725, WLN: T6MV DVMTJ C2 CR, MolPort-001-783-659, NINDS_000324, HMS1570L08, HMS1920J20, HMS2092A21, HMS2097L08, HMS2236G03, HMS3259K04, HMS3263M03, HMS3266H18, HMS3369J12, HMS3655L05, HMS3714L08, LS-48, Pharmakon1600-01500501, HY-B0339, KS-00000XM8, NSC41701, Tox21_110238, Tox21_201948, Tox21_303194, Tox21_501021, ANW-42020, BG0404, CCG-39231, NSC-41701, NSC757291, s1965, Sanofi-Synthelabo Brand of Primidone, SBB017254, AKOS003368409, Tox21_110238_1, API0003929, CS-2381, DB00794, KS-5217, LP01021, MCULE-2519004832, NC00532, NSC-757291, IDI1_000324, SMP1_000135, NCGC00015834-01, NCGC00015834-02, NCGC00015834-03, NCGC00015834-04, NCGC00015834-05, NCGC00015834-06, NCGC00015834-07, NCGC00015834-08, NCGC00015834-09, NCGC00015834-10, NCGC00015834-12, NCGC00015834-13, NCGC00015834-14, NCGC00015834-15, NCGC00015834-16, NCGC00015834-17, NCGC00015834-19, NCGC00016377-01, NCGC00023254-02, NCGC00023254-04, NCGC00023254-05, NCGC00023254-06, NCGC00023254-07, NCGC00023254-08, NCGC00023254-09, NCGC00023254-10, NCGC00257146-01, NCGC00259497-01, NCGC00261706-01, AN-22963, BC682375, CC-33920, CPD000058501, H808, SAM002554925, SC-18998, ST076725, ZB000454, SBI-0050994.P004, AB0013274, AB2000396, TR-003816, AB00052079, EU-0101021, FT-0603328, P1906, 5-Ethyldihydro-5-phenyl-4,5H)-pyrimidinedione, C07371, D00474, K-1838, 5-ethyl-5-phenyl-hexahydropyrimidine-4,6-dione, AB00052079-14, AB00052079_15, AB00052079_16, 125P337, 4,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl-, A805374, I06-0632, J-005215, SR-01000003162-2, SR-01000003162-4, SR-01000003162-5, SR-01000003162-8, BRD-K32247306-001-05-4, BRD-K32247306-001-17-9, 5-Ethyl-5-phenyldihydro-4,6(1H,5H)-pyrimidinedione #, Primidone, European Pharmacopoeia (EP) Reference Standard, Primidone, United States Pharmacopeia (USP) Reference Standard, Primidone for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 504

InChIKey: DQQCJDBYNZMPOA-FFXKMJQXSA-N
SMILES: CN1CCC2=CC=CC3=C2[C@H]1CC4=C3C(=C(C=C4)O)O.O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6852399
synonyms found at PubChem are:
R-(-)-Apomorphine, MLS000069811, Apomorphine hydrochloride hemihydrate, 41372-20-7, SMR000059235, R-(-)-Apomorphine hydrochloride hemihydrate, SMR000653528, (R)-Apomorphine Hydrochloride Hemihydrate, Opera_ID_1132, MLS001074112, MLS002153277, MLS002222153, C17H17NO2.ClH.H2O, SCHEMBL5429071, CHEMBL1256708, HW2A207, 2223AH, AKOS030526144, NCGC00180984-01, SMR001307246, R(-) Apomorphine hydrochloride hemihydrate, MLS-0235817.0001, (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride hydrate

ID: 505

InChIKey: DQUMVRSTGOLXHO-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC=CC=C1OCC2=CC=C(C=C2)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 9899825
synonyms found at PubChem are:
1-{2-[(4-methoxybenzyl)oxy]phenyl}ethanone, 371258-91-2, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]ethanone, SCHEMBL4938231, CTK1A9683, DTXSID80432562, DQUMVRSTGOLXHO-UHFFFAOYSA-N, 2'-(4-Methoxybenzyloxy)acetophenone, ZINC19475899, AKOS000180550, A1-05667, Ethanone, 1-[2-[(4-methoxyphenyl)methoxy]phenyl]-

ID: 506

InChIKey: DQVARXSGNFBPMB-UHFFFAOYSA-N
SMILES: COC1=CC=CC(=C1)C(=O)NCCN2CCN(CC2)C3=CC=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3626837
synonyms found at PubChem are:
N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide, CHEMBL93403, N-[2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl]-3-methoxybenzamide, n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide, N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide, AC1MTLV6, Lopac-C-7230, Lopac0_000287, MLS002153518, SCHEMBL1322020, CTK8G1437, HMS2230B03, HMS3260J16, HMS3373J10, PB-12, Tox21_500287, BDBM50068366, AKOS024728383, CCG-204382, LP00287, NCGC00015262-01, NCGC00015262-02, NCGC00015262-03, NCGC00015262-04, NCGC00093740-01, NCGC00093740-02, NCGC00260972-01, SMR001230850, EU-0100287, C 7230, SR-01000075777, SR-01000075777-1, F5264-0494, N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide

ID: 507

InChIKey: DQWQITFUWFBXON-UHFFFAOYSA-N
SMILES: COC(=O)C1=CC(=O)C(=C2C(=C1)C=CC(=C2O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5098884
synonyms found at PubChem are:
METHYL 7-DESHYDROXYPYROGALLIN-4-CARBOXYLATE, KBio2_003236, Spectrum_000188, SpecPlus_000185, Spectrum2_000602, Spectrum3_000223, Spectrum4_001438, Spectrum5_000296, AC1NP3I1, BSPBio_001865, KBioGR_001916, KBioSS_000668, SPECTRUM201505, DivK1c_006281, SPBio_000504, CHEMBL1556914, SCHEMBL12609926, KBio1_001225, KBio2_000668, KBio2_005804, KBio3_001365, DQWQITFUWFBXON-UHFFFAOYSA-N, MolPort-002-744-054, ZINC3198921, CCG-39164, STK785494, AKOS005621142, MCULE-6169483466, NCGC00095922-01, NCGC00095922-02, NCGC00178939-01, ST085228, A4092/0174489, methyl 3,4,5-trihydroxy-6-oxobenzo[7]annulene-8-carboxylate, methyl 2,8,9-trihydroxy-1-oxobenzo[c][7]annulene-4-carboxylate, methyl 3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulene-8-carboxylate, 5H-Benzo[a]cycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-5-oxo-, methyl ester

ID: 508

InChIKey: DRCMAZOSEIMCHM-UHFFFAOYSA-N
SMILES: C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2549
synonyms found at PubChem are:
capsazepine, 138977-28-3, capsazepin, N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide, UNII-LFW48MY844, N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, CHEMBL391997, LFW48MY844, ST50826300, CHEBI:70773, 2-[2-(4-chlorophenyl)ethylamino-thiocarbonyl]-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine, N-(2-[4-chlorophenyl]ethyl)-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide, N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide, SR-01000075437, capasazepine, Tocris-0464, Lopac-C-191, AC1MBZ0D, D0G8BN, Lopac0_000373, BSPBio_001550, KBioGR_000270, KBioSS_000270, MLS002153524, SCHEMBL122421, GTPL2461, BDBM20284, CTK8E8275, KBio2_000270, KBio2_002838, KBio2_005406, KBio3_000539, KBio3_000540, DTXSID20160852, DRCMAZOSEIMCHM-UHFFFAOYSA-N, MolPort-003-845-575, Bio1_000394, Bio1_000883, Bio1_001372, Bio2_000270, Bio2_000750, HMS1361N12, HMS1791N12, HMS1989N12, HMS2230F13, HMS3261K07, HMS3266C14, HMS3372M06, HMS3402N12, HMS3650G17, NK101, BCP12782, ZINC3871859, Tox21_500373, 1660AH, BG0125, MFCD00153778, s8137, AKOS024458271, Capsazepine, >=98% (HPLC), solid, CCG-204468, CS-1572, LP00373, IDI1_034020, KS-0000180V, NCGC00015190-01, NCGC00015190-02, NCGC00015190-03, NCGC00015190-04, NCGC00015190-05, NCGC00015190-06, NCGC00015190-07, NCGC00024602-01, NCGC00024602-02, NCGC00024602-03, NCGC00024602-04, NCGC00261058-01, ACM138977283, AN-31786, HY-15640, LS-27974, SC-97943, SMR001230854, RT-011911, C-191, EU-0100373, FT-0664232, 7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide, 977C283, J-007205, SR-01000075437-1, SR-01000075437-3, SR-01000075437-7, BRD-K44849676-001-03-0, N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-, 2-({[2-(4-chlorophenyl)ethyl]amino}thioxomethyl)-1H,3H,4H,5H-benzo[e]azepine-7 ,8-diol, N-(4-Chlorophenethyl)-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide, N-(4-chlorophenethyl)-7,8-dihydroxy-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carbothioamide, 6ET, N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine-2-carbothioamide

ID: 509

InChIKey: DRKXOTFIYYKGMI-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=CS3)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "O Zegarra-Moran" "LJ Galietta" "GL Lukacs" "K Du" "AS Verkman" "N Pedemonte"

CID is 734128
synonyms found at PubChem are:
N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]thiophene-2-carboxamide, (E)-N-(4-(3,4-dimethylphenyl)thiazol-2(3H)-ylidene)thiophene-2-carboxamide, 313374-94-6, AC1LED22, Oprea1_191452, SCHEMBL838040, IFLab1_000229, MolPort-002-274-721, MolPort-003-009-184, HMS1412K09, ZINC4031545, STL230210, AKOS000928713, AKOS024573936, MCULE-3709003538, IDI1_008448, EU-0067591, SR-01000394931, SR-01000394931-1, Z28298877, F0013-0146

ID: 510

InChIKey: DRLFMBDRBRZALE-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 896
synonyms found at PubChem are:
Melatonin, 73-31-4, Melatonine, N-Acetyl-5-methoxytryptamine, Circadin, 5-Methoxy-N-acetyltryptamine, N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide, N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide, Melatol, Melatonex, Melovine, N-[2-(5-methoxyindol-3-yl)ethyl]acetamide, Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-, Melapure, Posidorm, Vivitas, Pineal Hormone, Sleep Right, UNII-JL5DK93RCL, Night Rest, Rx Balance, Revital Melatonin, [3H]melatonin, Nature'S Harmony, Melatonina (TN), N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide, Mela-T, [3H]-melatonin, N-acetyl-5-methoxy-tryptamine, NSC 113928, CCRIS 3472, CHEMBL45, EINECS 200-797-7, IN1244, JL5DK93RCL, Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-, BRN 0205542, [3H]MLT, CHEBI:16796, PREVENTION 2 (MELATONIN), PREVENTION 3 (MELATONIN), PREVENTION 4 (MELATONIN), PREVENTION 5 (MELATONIN), DRLFMBDRBRZALE-UHFFFAOYSA-N, M-1200, M-1250, Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-, TNP00300, Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-, N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide, NSC113928, MT6, CAS-73-31-4, NCGC00015680-11, NMR/14327425, 3-(n-acetyl-2-aminoethyl)-5-methoxyindole, M1105, DSSTox_CID_2421, M 5250, DSSTox_RID_76585, DSSTox_GSID_22421, PREVENTION 1 (MELATONIN) (PREVENTION 1), 8041-44-9, Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}, Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}, 4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID, WLN: T56 BMJ D2MV1 GO1, ML1, SMR000326666, N-(2-(5-methoxyindol-3-yl)ethyl)-Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-Acetamide, N-[2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide, SR-01000075559, Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-(9CI), Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-(9CI), Melatonina, Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI), Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI), Melatonine;, Guna-dermo, HSDB 7509, Melatonin (MLT), Prestwick_312, Melatonex, Melatonin, PubChem18245, Spectrum_000185, Guna-dermo (Salt/Mix), Prestwick0_000458, Prestwick1_000458, Prestwick2_000458, Prestwick3_000458, Spectrum2_001344, Spectrum3_001393, Spectrum4_000066, Spectrum5_001745, Lopac-M-5250, Melatonin, 99% 5g, ChemDiv2_003916, D0AN7B, D0B5CB, D0M9SI, Melatonex, 73-31-4, Melatonin, >=99.5%, AC1L1A9Q, AC1Q4F1W, AC1Q4F1X, Lopac0_000787, Oprea1_104553, Oprea1_814234, SCHEMBL19018, BSPBio_000536, BSPBio_003006, GTPL224, KBioGR_000591, KBioSS_000665, 5-22-12-00042 (Beilstein Handbook Reference), KSC498C4R, MLS000859594, MLS001055382, MLS001240204, ARONIS24462, BIDD:ER0618, DivK1c_000353, SPECTRUM1500690, SPBio_001527, SPBio_002475, Melatonin (synth.) ultra-pure, ACE073, BDBM9019, BPBio1_000590, GTPL1357, DTXSID1022421, CTK3J8148, HMS501B15, KBio1_000353, KBio2_000665, KBio2_003233, KBio2_005801, KBio3_002226, ZINC57060, BBC/626, BIM0105, Melatonin 1.0 mg/ml in Methanol, MolPort-000-737-883, NINDS_000353, ZX-AFC003034, HMS1380B22, HMS1569K18, HMS1921E04, HMS2089F09, HMS2096K18, HMS2233D23, HMS3262M16, HMS3370J20, HMS3654A22, HMS3713K18, Melatonin (synth.) standard-grade, ACT03490, BCP28154, HY-B0075, KS-00000GX9, NSC56423, ZX-AS004827, Tox21_110195, Tox21_201527, Tox21_302926, Tox21_500787, ANW-42685, BG0247, CCG-38837, CM-539, GP8408, HSCI1_000400, KM1545, Melatonin, powder, >=98% (TLC), MFCD00005655, NSC-56423, SBB003265, STK386880, AKOS000276269, Tox21_110195_1, CS-1769, DB01065, KS-1454, LP00787, LS-1623, MCULE-1497884152, NSC-113928, RP17870, RTC-063565, SDCCGMLS-0065812.P001, SDCCGMLS-0065812.P002, SHG0000005, IDI1_000353, IDI1_002631, KS-000048J8, SMP2_000309, N-acetyl-5-methoxy-tryptamine Melatonine, NCGC00015680-01, NCGC00015680-02, NCGC00015680-03, NCGC00015680-04, NCGC00015680-05, NCGC00015680-06, NCGC00015680-07, NCGC00015680-08, NCGC00015680-09, NCGC00015680-10, NCGC00015680-12, NCGC00015680-13, NCGC00015680-14, NCGC00015680-15, NCGC00015680-16, NCGC00015680-18, NCGC00090727-01, NCGC00090727-02, NCGC00090727-03, NCGC00090727-04, NCGC00090727-05, NCGC00090727-06, NCGC00090727-07, NCGC00090727-08, NCGC00090727-09, NCGC00256404-01, NCGC00259077-01, NCGC00261472-01, 4CN-3100, AC-10019, AJ-09558, AK110931, BAS 01281092, BC200187, NCI60_004378, SC-16475, ST057260, ZB001948, AB0007332, AB2000011, KB-178582, TC-063565, AB00053279, EU-0100787, FT-0628191, FT-0658928, S1204, ST24031293, C01598, D08170, J10164, AB00053279-10, AB00053279_12, {N-[2-(5-methoxyindol-3-yl)ethyl]-} Acetamide, 005M655, L001261, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-Acetamide, I05-0076, I10-0345, SR-01000075559-1, SR-01000075559-6, SR-01000075559-7, SR-01000075559-8, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide, BRD-K97530723-001-07-6, BRD-K97530723-001-11-8, F1929-1777, 0E2B08C1-B325-45B1-8939-6F9081EFDFA4, A4039/0172195, Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI), Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-(6CI,8CI), Melatonin, United States Pharmacopeia (USP) Reference Standard, Disodium 4-acetamido-4'-isothiocyanato-stilben-2,2'-disulfonate, Melatonin, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 511

InChIKey: DRZDMSPFGPTPER-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)C3=C(C=C(C=C3)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603717
synonyms found at PubChem are:
N-(4-Amino-2-chlorophenyl)phthalimide, 19348-53-9, 2-(4-amino-2-chlorophenyl)isoindoline-1,3-dione, 2-(4-amino-2-chlorophenyl)-1H-isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione,2-(4-amino-2-chlorophenyl)-, 2-(4-amino-2-chlorophenyl)-2,3-dihydro-1H-isoindole-1,3-dione, NCGC00015106-01, AC1O7FZU, Lopac-A-9345, AC1Q51LZ, Lopac0_000153, MLS002153513, CHEMBL278755, SCHEMBL1322530, ZINC8695, CTK4E1267, DTXSID90424953, MolPort-004-307-504, HMS2230F03, HMS3260O08, HMS3372L10, Tox21_500153, MFCD00658249, AKOS000142827, CCG-204248, LP00153, MCULE-6724628192, NE11647, NCGC00015106-02, NCGC00015106-03, NCGC00015106-04, NCGC00093643-01, NCGC00093643-02, NCGC00260838-01, DA-08690, SMR001230845, EU-0100153, FT-0720847, EN300-41106, A 9345, 2-(4-amino-2-chlorophenyl)isoindole-1,3-dione, SR-01000075694, J-012528, SR-01000075694-1, 2-(4-Amino-2-chlorophenyl)-2H-isoindole-1,3-dione

ID: 512

InChIKey: DSGOSRLTVBPLCU-UHFFFAOYSA-N
SMILES: C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957552
synonyms found at PubChem are:
Fenoldopam Hydrobromide, Fenoldopam bromide, 67287-54-1, Fenoldopam monohydrobromide, SKF-82526, SMR000875267, 67227-56-9 (Parent), SR-01000075882, EINECS 266-634-7, SKF 82526 Hydrobromide, MLS001333093, MLS001333094, SCHEMBL1319766, CHEMBL1256646, DSGOSRLTVBPLCU-UHFFFAOYSA-N, 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol monohydrobromide, AOB33784, Fenoldopam monohydrobromide, >=98%, Tox21_500556, AKOS030558287, CCG-221860, LP00556, 6-Chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide, NCGC00093942-01, NCGC00261241-01, AS-16645, EU-0100556, FT-0668498, EN300-207690, F 6800, SR-01000075882-1, ( inverted exclamation markA)-Fenoldopam Hydrobromide, ( inverted exclamation markA)-SKF 82526 Hydrobromide, 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol Hydrobromide, 6-Chloro-7,8-dihydroxy-1-p-hydroxyphenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, 6-Chloro-7,8-dihydroxyl-1-p-hydroxyphenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

ID: 513

InChIKey: DSKIOWHQLUWFLG-SPIKMXEPSA-N
SMILES: CN1CCN(CC1)CCCN2C3=C(SC4=CC=CC=C24)C=CC(=C3)Cl.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281032
synonyms found at PubChem are:
Prochlorperazine dimaleate, Prochlorperazine maleate, 84-02-6, UNII-I1T8O1JTL6, Buccastem, Emetiral, Pasotomin, Prochlorperazine dimaleate salt, Nibromin A, Meterazin maleate, Stemetil dimaleate, I1T8O1JTL6, Proclorperazine maleate, Prochlorperazinu dimaleat, Prochlorperazine bimaleate, Prochlorperazine hydrogen maleate, Prochloroproazine hydrogen maleate, Prochlorperazinu dimaleat [Czech], Compazine (TN), EINECS 201-511-3, DSSTox_CID_28941, DSSTox_RID_83206, DSSTox_GSID_49015, C20H24ClN3S.2C4H4O4, CHEBI:8436, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine dimaleate, 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine, dimaleate, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine maleate (1:2), CAS-84-02-6, SR-01000000260, NCGC00015856-08, 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate (1:2), (Z)-but-2-enedioic acid;2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine, Prestwick_410, Prochlorperazine maleate [USP:JAN], AC1NQXXB, Prochlorperazin-dimaleat, (Z)-but-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine, 2-Chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine dimaleate, Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, maleate (1:2), SCHEMBL40755, CHEMBL1314751, DTXSID1049015, MolPort-001-727-970, HMS1569O19, HMS2096O19, HMS3263O09, HMS3713O19, Tox21_113522, Tox21_501034, MFCD00069330, Prochlorperazine maleate (JP17/USP), AKOS024457528, Tox21_113522_1, CCG-220399, CCG-222338, LP01034, NCGC00015856-10, NCGC00094323-01, NCGC00261719-01, AS-13744, EU-0101034, P2368, W0066, D00479, J10225, P 9178, SR-01000000260-2, SR-01000000260-9, 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine Dimaleate, Prochlorperazine maleate, British Pharmacopoeia (BP) Reference Standard, Prochlorperazine maleate, European Pharmacopoeia (EP) Reference Standard, 2-Chloro-10-[3[(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine dimaleate, Prochlorperazine maleate, United States Pharmacopeia (USP) Reference Standard, AC1NUWJK, 2-chloro-10-[3-(4-methylpiperazine-1,4-diium-1-yl)propyl]phenothiazine; (Z)-4-hydroxy-4-oxobut-2-enoate, 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioic acid]

ID: 514

InChIKey: DSSOOOVNLBRAPY-UHFFFAOYSA-N
SMILES: CC(C)(C)C1CCC2(CC1)NC(=S)N(N2)C3=NC4=CC=CC=C4S3

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "O Zegarra-Moran" "LJ Galietta" "GL Lukacs" "K Du" "AS Verkman" "N Pedemonte"

CID is 608835
synonyms found at PubChem are:
2-Benzothiazol-2-yl-8-tert-butyl-1,2,4-triaza-spiro[4.5]decane-3-thione, AC1LO30S, Oprea1_280562, SCHEMBL837825, DSSOOOVNLBRAPY-UHFFFAOYSA-N, MolPort-002-710-202, ZINC1067812, STK764818, AKOS001746223, A2544/0108255, 1,2,4-Triazaspiro[4.5]decane-3-thione, 2-(2-benzothiazolyl)-8-tert-butyl-, 2-(1,3-benzothiazol-2-yl)-8-tert-butyl-1,2,4-triazaspiro[4.5]decane-3-thione, 2-(benzo[d]thiazol-2-yl)-8-tert-butyl-1,2,4-triazaspiro[4.5]decane-3-thione, 3-(1,3-benzothiazol-2-yl)-8-tert-butyl-1,3,4-triazaspiro[4.5]decane-2-thione

ID: 515

InChIKey: DSSYKIVIOFKYAU-PVSHWOEXSA-N
SMILES: CC1([C@@H]2CCC1(C(=O)C2)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6857773
synonyms found at PubChem are:
SR-05000001993, 1R-CAMPHOR, AC1OAH6S, SPECTRUM1500156, SCHEMBL16582770, HMS1920I11, HMS2091O13, CCG-38655, SDCCGMLS-0066642.P001, (1R)-4,7,7-trimethylbicyclo[2.2.1]heptan-3-one, SR-05000001993-1, SR-05000001993-3

ID: 516

InChIKey: DTCZZBVPTHVXFA-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2C)OC)OC)C.Cl

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3060974
synonyms found at PubChem are:
Trequinsin hydrochloride, HL 725, 78416-81-6, TCMDC-125545, Trequinsin, Hydrochloride, HL-725, NCGC00094424-01, DSSTox_CID_25806, DSSTox_RID_81144, DSSTox_GSID_45806, 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, 9,10-Dimethoxy-2-mesitylimino-3-methyl-2,3,6,7-tetrahydro-4H-pyrimido-(6,1-a)-isoquinolin-4-one, HCl, CAS-78416-81-6, Trequinsin HCl, Trequinsinhydrochlorid, AC1MI0R6, C24H27N3O3.HCl, CHEMBL527956, SCHEMBL7327917, CHEMBL1256910, DTXSID8045806, CTK8G3572, MolPort-023-276-400, Trequinsin hydrochloride, >=98%, 79855-88-2 (Parent), Tox21_111279, Tox21_501165, MFCD01076563, AKOS024457057, Tox21_111279_1, CCG-222469, LP01165, NCGC00092376-01, NCGC00092376-06, NCGC00261850-01, LS-136233, B7022, EU-0101165, FT-0630860, T 2057, SR-01000076150, SR-01000076150-1, 2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride, 9,10-dimethoxy-3-methyl-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one hydrochloride, AC1Q1SZQ, SCHEMBL6375918, 9,10-dimethoxy-3-methyl-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[4,3-a]isoquinolin-4-one hydrochloride

ID: 517

InChIKey: DTFARBHXORYQBF-ORYQWCPZSA-N
SMILES: CC(C)[C@@H]1CC2=C(O1)C=CC3=C2O[C@H]4COC5=CC(=C(C=C5[C@H]4C3=O)OC)OC

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "D Zhang" "Y Luo" "JW Hanrahan" "R Robert" "KA Teske" "GW Carlile"

CID is 73068
synonyms found at PubChem are:
Dihydrorotenone, (2s,6ar,12ar)-8,9-dimethoxy-2-(propan-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6ah)-one, Caswell No. 353, Dihydrorotenone (VAN), 1',2'-Dihydrorotenone, Rotenone, dihydro- (VAN), NSC 53866, EPA Pesticide Chemical Code 071002, NSC 351138, AC1L2J7Q, AC1Q6KP8, CTK5C4931, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6a-alphah)-one, 1,2,12,12a-alpha-tetrahydro-2-alpha-isopropyl-8,9-dimethoxy-, LS-39365, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropyl-8,9-dimethoxy-, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-, (2R-(2alpha,6aalpha,12aalpha))-

ID: 518

InChIKey: DTNGBIGBPPPNNB-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(C(=C(C=C2O1)O)CC=C(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 68477
synonyms found at PubChem are:
Peucenin, 578-72-3, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-methyl-6-(3-methyl-2-butenyl)-, 5,7-Dihydroxy-2-methyl-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one, Chromone, 5,7-dihydroxy-2-methyl-6-(3-methyl-2-butenyl)-, Spectrum_000553, SpecPlus_000018, AC1Q6AFP, Spectrum2_000344, Spectrum3_000095, Spectrum4_001371, Spectrum5_000042, BSPBio_001650, KBioGR_001662, KBioSS_001033, SPECTRUM100528, DivK1c_006114, SPBio_000407, AC1L29T7, CHEMBL1415085, SCHEMBL15106595, CTK1H3643, KBio1_001058, KBio2_001033, KBio2_003601, KBio2_006169, KBio3_000750, DTNGBIGBPPPNNB-UHFFFAOYSA-N, CCG-38619, AKOS030553263, SDCCGMLS-0066289.P001, NCGC00095426-01, NCGC00095426-02, NCGC00179118-01, 5,7-dihydroxy-2-methyl-6-4h-1-benzopyran-4-one, SR-05000002510, SR-05000002510-1, BRD-K73103240-001-03-3, 5,7-dihydroxy-2-methyl-6-(3-methylbut-2-enyl)chromone, 5,7-dihydroxy-2-methyl-6-(3-methylbut-2-enyl)chromen-4-one, 5,7-Dihydroxy-2-methyl-6-(3-methyl-2-butenyl)-4H-chromen-4-one #

ID: 519

InChIKey: DTNMUOXAPMXVHZ-UHFFFAOYSA-N
SMILES: C(C1=C(SCC(=O)OC)C=CS1)1C(C(=O)OCC=C)=C(C)NC(C)=C1C(=O)OCC=C

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "M Zacchigna" "LJ Galietta" "F Cateni" "M Giampieri" "MT Mazzei" "N Pedemonte" "M Mazzei"

CID is 46227419
synonyms found at PubChem are:
CHEMBL596405

ID: 520

InChIKey: DTOUUUZOYKYHEP-UHFFFAOYSA-N
SMILES: CCCCC(CC)CN1CC(CN(C1)CC(CC)CCCC)(C)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3607
synonyms found at PubChem are:
hexetidine, 141-94-6, Oraldene, Hexoral, Glypesin, Hextril, Elsix, Collu hextril, Sterilate, Sterisil, Triocil, Triscol, Duranil Aerosol, Hexetidinum, Collu-Hextril, Steri/Sol, Drossadin, Hexetidina, Oraseptic, Paradenyl, Steri/Sol (VAN), Caswell No. 033BB, Hexetidinum [INN-Latin], Hexetidina [INN-Spanish], NSC 17764, 5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-, C21H45N3, EINECS 205-513-5, 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine, AI3-15546, MLS002207232, 5-Amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine, 5-Amino-1,3-bis(2-ethylhexyl)hexahydro-5-methylpyrimidine, P 252, DTOUUUZOYKYHEP-UHFFFAOYSA-N, Hexetidine, mixture of stereoisomers, 1,3-Bis(2-ethylhexyl)-5-amino-hexahydro-5-methylpyrimidin, DSSTox_CID_25297, DSSTox_RID_80788, DSSTox_GSID_45297, 1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidiamine, 5-Amino-1,3-bis(2-ethylhexyl)-5-methyl-hexhydropyrimidine, Hexigel, Pyrimidine, 5-amino-1,3-bis(2-ethylhexyl)hexahydro-5-methyl-, Hexetidine [BAN], Hexetidine [INN:BAN], SR-01000872662, Hexopyrimidine, Esetidina, Hexetidin, Hexocil, 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazaperhydroine-5-ylamine, HSDB 7828, NCGC00016404-01, CAS-141-94-6, Hexetidine (INN), Prestwick_800, Spectrum_000236, Prestwick0_000551, Prestwick1_000551, Prestwick2_000551, Prestwick3_000551, Spectrum2_000953, Spectrum3_000271, Spectrum4_000395, Spectrum5_001435, AC1L1GB5, AC1Q2V9B, AC1Q4V4W, SCHEMBL56672, BSPBio_000621, BSPBio_001742, KBioGR_000949, KBioSS_000716, DivK1c_000280, SPECTRUM1500633, SPBio_000946, SPBio_002542, BPBio1_000685, CHEMBL144673, DTXSID1045297, CHEBI:94339, CTK8G0178, HMS500N22, KBio1_000280, KBio2_000716, KBio2_003284, KBio2_005852, KBio3_001242, MolPort-001-770-543, NINDS_000280, HMS1569P03, HMS1921M09, HMS2096P03, HMS3713P03, Pharmakon1600-01500633, HY-B0996, NSC17764, ZX-AT010428, Tox21_110424, CCG-39752, NSC-17764, NSC757394, OR8156, SBB001384, AKOS000277944, AKOS024348907, Tox21_110424_1, CS-4490, DB08958, MCULE-8471986715, NSC-757394, IDI1_000280, NCGC00094819-01, NCGC00094819-02, NCGC00094819-03, NCGC00094819-04, NCGC00094819-07, AN-43898, CC-29333, SMR000059080, SBI-0051566.P002, KB-270000, LS-173102, AB00052133, FT-0627047, ST50826237, X6883, D07068, AB00052133_06, 141H946, C-20302, Pyrimidine,3-bis(2-ethylhexyl)hexahydro-5-methyl-, SR-01000872662-1, SR-01000872662-2, I14-44805, 5-Pyrimidinamine,3-bis(2-ethylhexyl)hexahydro-5-methyl-, 1,3-bis(2-ethylhexyl)-5-methyl-hexahydropyrimidin-5-amine, 1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine, 5-pyrimidinamine,1,3-bis(2-ethylhexyl)hexahydro-5-methyl-, Hexetidine, European Pharmacopoeia (EP) Reference Standard, 1,3-Bis(2-ethylhexyl)-5-methylhexahydro-5-pyrimidinamine #, Pyrimidine, 5-amino-1,3-bis(2-ethylhexyl)hexahydro-5-methyl- (8CI)

ID: 521

InChIKey: DTSOZYYWEZJFSS-XTHCGPPUSA-N
SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16218899
synonyms found at PubChem are:
Amikacin hydrate, 1257517-67-1, BAY416651 hydrate, MLS002207279, SMR001306795, N1-[(S)-4-Amino-2-hydroxybutyryl]kanamycin A, SCHEMBL2172496, CHEMBL1879513, BDBM91426, cid_16218899, DTSOZYYWEZJFSS-XTHCGPPUSA-N, C22H43N5O13.H2O, HY-B0509, 2212AH, AKOS030627375, CS-2711, Amikacin hydrate, aminoglycoside antibiotic, 1257517-67-1,37517-28-5(freebase), (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]

ID: 522

InChIKey: DUECABXXAMFFBH-CYBMUJFWSA-N
SMILES: CC(=C)[C@H]1COC2=C(O1)C=C3C=CC(=O)OC3=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708593
synonyms found at PubChem are:
OBLIQUIN, 16167-05-8, KBio2_006211, Spectrum_000595, SpecPlus_000178, AC1O8FER, Spectrum2_000348, Spectrum3_000100, Spectrum4_001382, Spectrum5_000084, BSPBio_001660, KBioGR_001704, KBioSS_001075, SPECTRUM100540, DivK1c_006274, SPBio_000415, CHEMBL3039091, SCHEMBL12062102, KBio1_001218, KBio2_001075, KBio2_003643, KBio3_000760, CHEBI:113544, CCG-38623, SDCCGMLS-0066301.P001, SR-05000002491, SR-05000002491-1, BRD-K88954184-001-03-0, (2S)-2-prop-1-en-2-yl-2,3-dihydropyrano[2,3-g][1,4]benzodioxin-7-one

ID: 523

InChIKey: DUHUCHOQIDJXAT-OLVMNOGESA-N
SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 104845
synonyms found at PubChem are:
Alfaxalone, Alphaxalone, 23930-19-0, 5alpha-Pregnan-3alpha-ol-11,20-dione, alfaxolone, Alfaxalonum [INN-Latin], GR 2/234, Alfaxalona [INN-Spanish], 3alpha-Hydroxy-5alpha-pregnane-11,20-dione, UNII-BD07M97B2A, BRN 3217240, Alfadione, 3alpha-Hydroxy-5alpha-pregnan-11,20-dion, MLS000069684, MLS001076262, BD07M97B2A, CHEMBL190279, CHEBI:34531, 3-alpha-Hydroxy-5-alpha-pregnane-11,20-dione, (3-alpha,5-alpha)-3-Hydroxypregnane-11,20-dione, 3-Hydroxypregnane-11,20-dione, NCGC00023100-03, SMR000058494, DSSTox_CID_2576, DSSTox_RID_76638, Alphaxolone, DSSTox_GSID_22576, 5-alpha-Pregnane-11,20-dione, 3-alpha-hydroxy-, Alfaxalona, Alfaxalonum, (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one, delta(16)-alfaxalone, SR-01000000168, Alfaxalone [INN:DCF:JAN], 5alpha-alphaxalone, Alfaxalone [INN:BAN:DCF:JAN], Alfaxalone (INN), CAS-23930-19-0, AC1L2XLT, Opera_ID_1629, Prestwick0_001002, Prestwick1_001002, Prestwick2_001002, Prestwick3_001002, D06UBH, 3 alpha-hydroxy-5 alpha-pregnane-11,20-dione, BIDD:PXR0037, Lopac0_000929, SCHEMBL57756, BSPBio_001123, 4-08-00-02091 (Beilstein Handbook Reference), SPBio_003004, BPBio1_001237, GTPL5461, DTXSID9022576, CTK8F7676, DUHUCHOQIDJXAT-OLVMNOGESA-N, MolPort-003-959-279, HMS1571I05, HMS2098I05, HMS2236N05, HMS3262J20, HMS3715I05, ZINC4081122, Tox21_110884, Tox21_500929, BDBM50164570, AKOS024457399, Tox21_110884_1, API0010033, CCG-205010, DB11371, LP00929, 5alpha-pregnane-3alpha-ol-11,20-dione, NCGC00023100-04, NCGC00023100-05, NCGC00023100-06, NCGC00023100-08, NCGC00261614-01, (3a,5a)-3-Hydroxypregnane-11,20-dione, LS-118546, (3?,5?)-3-Hydroxypregnane-11,20-dione, AB00384358, B7253, EU-0100929, C13803, D07282, P 5052, (3alpha,5alpha)-3-hydroxypregnane-11,20-dione, Pregnane-11,20-dione, 3-hydroxy-, (3a,5a)-, SR-01000076070, J-015280, SR-01000000168-2, SR-01000000168-3, SR-01000076070-1, BRD-K41445866-001-03-0, Pregnane-11,20-dione, 3-hydroxy-, (3-alpha,5-alpha)-, 5alpha-Pregnan-3alpha-ol-11,20-dione, powder, >=98% (TLC), Pregnane-11,20-dione, 3-hydroxy-, (3-alpha,5-alpha)- (9CI), (3R,5S,8S,9S,10S,13S,14S,17S)-17-Acetyl-3-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-11-one, EY4

ID: 524

InChIKey: DUIBXZLCROUOFD-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1C(=O)O)O)C)OC(=O)C2=C(C(=C(C=C2C)OC)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5321461
synonyms found at PubChem are:
Baeomycesic acid, Baeomycessaure, Beomycesic acid, AC1NT0J3, CHEMBL2227773, SCHEMBL18621794, 644-66-6, 4-(3-formyl-2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid

ID: 525

InChIKey: DUIGUKRYYAGJAF-UHFFFAOYSA-N
SMILES: C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3.OP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 158798
synonyms found at PubChem are:
Antazoline phosphate, 154-68-7, Antazoline HO, UNII-VPR5FPH326, Antazoline phosphate [USP], Antazoline phosphate salt, VPR5FPH326, MLS000028623, SMR000058669, N-Benzyl-4,5-dihydro-N-phenyl-1H-imidazole-2-methylamine monophosphate, Antazoline phosphate (USP), Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine HO, 91-75-8 (Parent), N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline; phosphoric acid, N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline;phosphoric acid, EINECS 205-831-4, AC1L4KMX, Opera_ID_1677, SCHEMBL23316, MLS001148180, 2-yl)methyl)aniline phosphate, SPECTRUM1500126, cid_158798, CHEMBL1200550, CTK5J6286, HMS500E05, C17H19N3.H3PO4, DTXSID00165507, 2-((N-Benzylanilino)methyl)-2-imidazoline phosphate (1:1), HMS1920E05, HMS2091K05, HMS2235H13, HMS3372H07, Pharmakon1600-01500126, 6397AF, CCG-39133, NSC755865, AKOS015963420, API0001509, MCULE-6727478889, NSC-755865, 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, phosphate (1:1), NCGC00094590-01, NCGC00094590-02, NCGC00094590-03, AC-20134, AN-23332, N-benzyl-N-((4,5-dihydro-1H-imidazol-, FT-0766726, ST51037133, D02950, J-009133, SR-01000000255-4, 2-(N-BENZYLANILINOMETHYL) IMIDAZOLINE PHOSPHATE, (2-imidazolin-2-ylmethyl)phenylbenzylamine, phosphoric acid, Antazoline phosphate salt, analytical standard, for drug analysis, Antazoline phosphate, United States Pharmacopeia (USP) Reference Standard, N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline,phosphoric acid

ID: 526

InChIKey: DUQADSPERJRQBW-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C=C(C#N)C#N)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2046
synonyms found at PubChem are:
AG 126, Tyrphostin AG 126, 118409-62-4, AG-126, ag126, alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile, (3-Hydroxy-4-nitrobenzylidene)malononitrile, UNII-7YA4AMD1JC, 7YA4AMD1JC, IN1431, 2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile, Tyrphostin AG127, Propanedinitrile, ((3-hydroxy-4-nitrophenyl)methylene)-, Propanedinitrile,2-[(3-hydroxy-4-nitrophenyl)methylene]-, Tyrphostin A 10, SR-01000076182, AG-127, ACMC-20dhp9, AC1L1CSU, BiomolKI_000026, Lopac-T-9177, BiomolKI2_000034, UPCMLD-DP015, AC1Q5AT2, Lopac0_001272, BMK1-D2, BSPBio_001196, KBioGR_000536, KBioSS_000536, CHEMBL77387, BDBM4326, SCHEMBL1802883, UPCMLD-DP015:001, UPCMLD-DP015:002, CHEBI:94704, CTK4B0663, KBio2_000536, KBio2_003104, KBio2_005672, KBio3_000971, KBio3_000972, DTXSID80152117, MolPort-009-019-541, Bio2_000438, Bio2_000918, HMS1362L17, HMS1792L17, HMS1990L17, HMS3403L17, HMS3648K20, BCP29141, ZINC2560269, HSCI1_000134, CCG-100630, CS-8032, IDI1_002193, NCGC00016062-01, NCGC00016062-02, NCGC00016062-03, NCGC00016062-04, NCGC00016062-05, NCGC00016062-06, NCGC00016062-07, NCGC00094508-01, NCGC00094508-03, NCGC00094508-04, NCGC00094508-05, NCGC00094508-06, NCGC00094508-07, ACM118409624, benzylidenemalononitrile (BMN) deriv. 10, HY-108330, LS-172382, RT-011205, EU-0101272, 2-(3-hydroxy-4-nitrobenzylidene)malononitrile, T 9177, J-003748, SR-01000076182-1, SR-01000076182-4, BRD-K67506692-001-03-8, BRD-K67506692-001-04-6, Propanedinitrile, 2-[(3-hydroxy-4-nitrophenyl)methylene]-

ID: 527

InChIKey: DURULFYMVIFBIR-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=C(C=C1)NC(=O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4883
synonyms found at PubChem are:
practolol, 6673-35-4, Dalzic, Eraldin, Teranol, Practololum, Praktololu, Practololo [DCIT], Praktololu [Polish], Practololo, dl-Practolol, rac Practolol, ICI 50172, Eralzdin Practolol, Practololum [INN-Latin], AY 21011, 1-(4-Acetamidophenoxy)-3-isopropylamino-2-propanol, ICI-50172, Practolol [USAN:BAN:INN], (+-)-Practolol, CCRIS 1089, N-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide, (+/-)-Practolol, 4'-(2-Hydroxy-3-(isopropylamino)propoxy)acetanilide, N-(4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide, N-[4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETAMIDE, EINECS 229-712-1, CHEMBL6995, N-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide, CHEBI:258351, N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide, Acetamide, N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, NCGC00024810-02, AY-21011, N-{4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}acetamide, Acetamide,N-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, DSSTox_CID_1179, N-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide, DSSTox_RID_75993, DSSTox_GSID_21179, 4'-[2-Hydroxy-3-(Isopropylamino)propoxy]acetanilide, Acetanilide, 4'-(2-hydroxy-3-(isopropylamino)propoxy)-, Acetanilide, 4'-[2-hydroxy-3-(isopropylamino)propoxy]-, N-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, Prestwick_742, Acetamide, N-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, Spectrum_001454, AC1Q1QBZ, SR-01000597449, Practalol, Practolol [USAN:INN:BAN], Racemic Practolol, Cordialina (TN), Eraldina (TN), Practolol,(+), Practolol,(-), Cardiol (TN), CAS-6673-35-4, Eraldin (TN), Practolol (USAN), Praktol (TN), Teranol (TN), Dalzic (TN), Pralon (TN), Prestwick0_000332, Prestwick1_000332, Prestwick2_000332, Prestwick3_000332, Spectrum2_001572, Spectrum4_000859, Spectrum5_001123, D0KD1U, Oprea1_095524, SCHEMBL39925, BSPBio_000363, GTPL555, KBioGR_001497, KBioSS_001934, MLS002153779, DivK1c_000901, SPBio_001504, SPBio_002284, AC1L1J62, BPBio1_000401, DTXSID0021179, Practolol, >=95% (HPLC), BDBM25749, CTK5C5115, HMS502N03, KBio1_000901, KBio2_001934, KBio2_004502, KBio2_007070, DURULFYMVIFBIR-UHFFFAOYSA-N, MolPort-000-182-968, NINDS_000901, HMS1569C05, HMS2089I09, HMS2096C05, HMS2233K23, HMS3374G04, HMS3713C05, Tox21_110928, CCG-39350, STL489279, AKOS002685374, AKOS016054902, Tox21_110928_1, DB01297, MCULE-7992924679, NE25450, ( inverted exclamation markA)-Practolol, IDI1_000901, NCGC00024810-03, NCGC00024810-04, NCGC00024810-07, LS-10763, SMR001233163, I.C.I. 50,172, SBI-0051937.P002, AY-21,011, KB-294694, AB00052459, FT-0673986, Z3381, EN300-72170, C11696, D05587, L000491, SR-01000597449-1, SR-01000597449-2, SR-01000597449-4, 4-[2-Hydroxy-3-(isopropylamino)propoxy]-acetanilide, BRD-A41304429-001-04-9, BRD-A41304429-001-12-2, DL-4'-[2-Hydroxy-3-(isopropylamino)propoxy]acetanilide, Z274728816, N-(4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl)acetamide #, [3-(4-Acetylamino-phenoxy)-2-hydroxy-propyl]-isopropyl-ammonium, 23313-50-0

ID: 528

InChIKey: DUUGKQCEGZLZNO-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1O)C(=CN2)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1826
synonyms found at PubChem are:
5-Hydroxyindole-3-acetic acid, 54-16-0, 5-HIAA, 2-(5-hydroxy-1H-indol-3-yl)acetic acid, 5-Hydroxyindoleacetic acid, 5-Hydroxyheteroauxin, (5-Hydroxy-1H-indol-3-yl)acetic acid, 5-Oxyindoleacetic acid, 5-Hydroxy-IAA, 5-Hydroxy-3-indoleacetic acid, 5-Hydroxyindol-3-ylacetic acid, Hydroxyindoleacetic acid, 5-Hydroxy-1H-indole-3-acetic acid, 5-Hydroxyindolacetic acid, 5-Hydroxyindolylacetic acid, 1H-Indole-3-acetic acid, 5-hydroxy-, 1321-73-9, Indole-3-acetic acid, 5-hydroxy-, 5-Hydroxyindoleacetate, UNII-YHC763JY1P, NSC 90432, CCRIS 4423, 1H-Indoleacetic acid, hydroxy-, 5-hydroxy-indole-3-acetic acid, EINECS 200-195-4, BRN 0168797, YHC763JY1P, 5-Hydroxyindol-3-acetic acid, CHEBI:27823, DUUGKQCEGZLZNO-UHFFFAOYSA-N, 5-22-05-00203 (Beilstein Handbook Reference), 2-(5-hydroxyindol-3-yl)acetic acid, INDOLEACETIC ACID, 5-HYDROXY-, H-6200, 5-hydroxyindole acetate, 5-hydroxyindolylaceticacid, 5-Oxyindoleacetate, Hydroxyindoleacetate, HIAA, 5HIAA, ACMC-1BTZR, AC1L1CBR, Lopac-H-8876, CBMicro_013565, 5-Hydroxyindole-3-acetate, bmse000364, D02VPC, 5-Hydroxy-3-indolylacetate, 5-Hydroxyindol-3-ylacetate, AC1Q1HA7, 5-hydroxy-Indole-3-acetate, NCIOpen2_001406, Lopac0_000636, Oprea1_139007, 5-Hydroxyindole-3-aceticAcid, MLS000859593, SCHEMBL138121, CHEMBL395915, 5-Hydroxy-1H-indole-3-acetate, 5-Hydroxyindolyacetic Acid,(S), 5-HYDROXYINDOLE-3acetic acid, 5-hydroxyl indole-3-acetic acid, CTK4B7780, KS-00000VYP, MolPort-002-507-333, (5-hydroxyindol-3-yl)acetic acid, 5-hydroxy-indol-3-yl-acetic acid, HMS2230M10, HMS3261P14, HMS3372G16, ZINC185722, ALBB-006262, BB_NC-01187, NSC90432, ZX-AN058764, Tox21_500636, ANW-31980, BBL012272, MFCD00005639, NSC-90432, SBB003639, STK501256, 1H-Indole-3-aceticacid, 5-hydroxy-, AKOS003382389, CCG-221940, CS-W008253, FCH1114712, HY-W008253, LP00636, MCULE-5193831459, TRA0074741, VI30289, (5-hydroxy-1H-indol-3-yl)-acetic acid, NCGC00015522-01, NCGC00015522-02, NCGC00015522-03, NCGC00015522-04, NCGC00094003-01, NCGC00094003-02, NCGC00261321-01, 2-(5-Hydroxy-1H-indol-3-yl)aceticacid, AJ-17701, AK-57807, CC-21853, DS-15683, EN001070, Indole-3-acetic acid, 5-hydroxy-, 1H-, Indoleacetic acid, 5-hydroxy- (Related), KB-73537, LS-82180, SMR000326665, ST059601, (5-Hydroxy-1H-indol-3-yl)acetic acid #, AX8012895, DB-007055, KB-208728, ST2403989, TR-004414, TX-016059, 4CH-018708, BB 0260171, EU-0100636, FT-0081418, FT-0620472, FT-0679205, X6993, C05635, H 8876, H19318, C-08237, SR-01000075583, I04-5778, I10-0543, J-006135, SR-01000075583-1, 5-Hydroxyindole-3-acetic acid, >=98% (HPLC), crystalline, 74C13742-18FA-4D80-8B54-1B85D9463949, 113303-91-6, 99155-61-0, HID

ID: 529

InChIKey: DVGGLGXQSFURLP-VWMSDXGPSA-N
SMILES: C1=CC(=CC=C1/C=C/C(=O)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5320686
synonyms found at PubChem are:
Tiliroside, 20316-62-5, Trans-Tiliroside, Tribuloside, UNII-15M04TXR9M, 15M04TXR9M, CHEMBL266564, CHEBI:80944, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 6'-ester with 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 22153-44-2, AC1NSZRJ, D0IB3K, SCHEMBL23597, Tiliroside, analytical standard, MEGxp0_000169, MolPort-001-740-347, 4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-b-D-glucopyranosyl]oxy]-, BDBM50241244, ZINC17654711, AKOS015896718, MCULE-6075035042, NCGC00163634-01, LS-123660, W1685, kaempferol 3-O-(6"-O-p-coumaroyl)-glucoside, C17140, Kaempferol-3-O-(6''''-p-coumaroyl)-glucoside, 316T625, A814433, I07-0175, Q-100248, kaempferol-3-beta-D-(6-O-trans-p-coumaroyl)glucopyranoside, Kaempferol-3-O-(6-O-trans-p-coumaroyl)-.beta.-glucopyranoside, kaempferol-3-O-beta-D-(6''-(E)-p-coumaroyl)-glucopyranoside, kaempferol 3-O-(6'''' ''''-O-E-p-coumaroyl)-beta-D-glucopyranoside, (E)-((2R,3S,4S,5R,6S)-6-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-2H-pyran-2-yl)methyl 3-(4-hydroxyphenyl)acrylate, (E)-((2R,3S,4S,5R,6S)-6-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yloxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3-(4-hydroxyphenyl)acrylate, (E)-3-(4-hydroxyphenyl)-2-propenoic acid [(2R,3S,4S,5R,6S)-6-[[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-1-benzopyran-3-yl]oxy]-3,4,5-trihydroxy-2-oxanyl]methyl ester, [(2R,3S,4S,5R,6S)-6-[2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)-4-oxidanylidene-chromen-3-yl]oxy-3,4,5-tris(oxidanyl)oxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate, [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-chromen-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate, [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-.beta.-D-glucopyranosyl]oxy]-, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4E-1-benzopyran-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside

ID: 530

InChIKey: DVZQTPMQQXAHSQ-UHFFFAOYSA-N
SMILES: C1CCN2CC3CC(C2C1)CN4C3CCCC4=O.OCl(=O)(=O)=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5351561
synonyms found at PubChem are:
LUPANINE PERCHLORATE, NSC59268, 14691-01-1, Dodecahydro-7,14-methano-4H,6H-dipyrido(1,2-a:1,2-e)(1,5)diazocin-4-one monoperchlorate, EINECS 238-733-5, CHEMBL1979081, CHEMBL3186825, CTK4C5164, NSC95094, NSC-59268, NSC-95094, AKOS030255103, Dodecahydro-7,14-methano-4H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocin-4-one monoperchlorate, NCGC00095701-01, MolPort-000-757-301, AKOS024384307, MCULE-3593851047, ST51034517

ID: 531

InChIKey: DWFIBKRMQRGBJH-UHFFFAOYSA-N
SMILES: C(C([HH0])=O)1C(CCC=C)=NN(C2=CC=CC=C2)C=1OC

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 100967242
synonyms found at PubChem are:
1-Phenyl-3-(3-butenyl)-5-methoxy-1H-pyrazole-4-carbaldehyde

ID: 532

InChIKey: DWOIUCRHVWIHAH-UHFFFAOYSA-N
SMILES: CCC1(CC2=CC=CC=C2O1)C3=NCCN3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957548
synonyms found at PubChem are:
Efaroxan hydrochloride, 89197-00-2, RX 821037A, 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride, 2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-4,5-dihydro-1H-imidazolehydrochloride, 2-(2-ETHYL-2,3-DIHYDROBENZOFURAN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HCL, SR-01000075857, Efaroxan HCl, EU-0100521, MLS002153473, SPECTRUM2300218, CHEMBL539313, SCHEMBL1320556, CTK8F9416, DTXSID00474686, MolPort-003-941-265, Pharmakon1600-02300218, Tox21_500521, BN0204, MFCD00069270, NSC759562, AKOS022488640, CCG-214022, LP00521, NSC-759562, Efaroxan hydrochloride, >=98% (HPLC), NCGC00093915-01, NCGC00093915-02, NCGC00093915-03, NCGC00261206-01, AS-53724, SMR001230826, FT-0732645, E 3263, C-54152, SR-01000075857-1, SR-01000075857-3, SR-01000075857-6, 2-(2-Ethyl-2,3-dihydro-2-benzofuranyl)-4,5-dihydro-1H-imidazole hydrochloride, 2-(2-Ethyl-2,3-dihydrobenzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride

ID: 533

InChIKey: DWSGTFTVBLXELC-MOTQWOLNSA-N
SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(C3=CC=CC=C3)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6419941
synonyms found at PubChem are:
51-56-9, homatropine bromide, HOMATROPINE HYDROBROMIDE, Homatropine (Bromide), Homatropine hydrobromide (R,S), Isopto Homatropine, (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobromide, Homatropini bromidum, Homatropini hydrobromidum, Homatropinum hydrobromicum, (+-)-Homatropine bromide, Homatropine dl- hydrobromide, DSSTox_CID_25099, DSSTox_RID_80669, DSSTox_GSID_45099, Homatropine (bromhydrate d'), EINECS 200-105-3, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2-phenylacetate hydrobromide, NCGC00179630-03, 1alphaH,5alphaH-Tropan-3alpha-ol mandelate (ester) hydrobromide, Homatropine HBr, Benzeneacetic acid, alpha-hydroxy-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, HBr, endo-(+-), Prestwick_261, Homatropine hydrobromide [USP:JAN], Homatropine(Bromide), AC1O4WGN, CAS-51-56-9, NCGC00016230-01, rac Homatropine Hydrobromide, SCHEMBL41950, MLS002154189, hydrobromide salt of homatropine, 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, mandelate (ester), hydrobromide, CHEMBL1319362, DTXSID5045099, HY-B0547A, MolPort-006-110-080, HMS1568M05, Benzeneacetic acid, alpha-hydroxy-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, hydrobromide, Benzeneacetic acid, alpha-hydroxy-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, hydrobromide, endo-(+-)-, KS-00001F7O, Tox21_110034, Tox21_110318, s4025, Homatropine hydrobromide (JP17/USP), AKOS025117351, Tox21_110318_1, CCG-220062, CS-2649, NCGC00013718-01, AK-88682, SMR001233480, KB-277832, ST2402114, D01004, Benzeneacetic acid, alpha-hydroxy-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, hydrobromide (1:1), SCHEMBL14672464, I06-1257

ID: 534

InChIKey: DWTTZBARDOXEAM-JSGCOSHPSA-N
SMILES: C[C@H]1CCC[C@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 65434
synonyms found at PubChem are:
beta-Zearalanol, Taleranol, 42422-68-4, beta zearalanol, UNII-HUN219N434, CHEMBL491510, CHEBI:35071, P 1560, HUN219N434, P-1560, (3S,7S)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one, (3S,7S)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10,11,12-decahydro-1H-2-benzoxacyclotetradecin-1-one, Taleranolum, Taleranol [USAN:INN], Taleranolum [INN-Latin], Taleranol (USAN/INN), BIDD:ER0109, SCHEMBL343276, 2,4-Dihydroxy-6-(6|A,10-dihydroxyundecyl]benzoic acid |I-lactone, DTXSID3022532, DWTTZBARDOXEAM-JSGCOSHPSA-N, MolPort-002-941-952, beta-Zearalanol, ~98% (HPLC), AC1L2391, ZINC3831617, (6S,10S)-6-(6,10-Dihydroxyundecyl)-beta-resorcyclic acid mu-lactone, BDBM50250268, MFCD00151077, STK078170, AKOS001582522, CCG-208500, MCULE-3886817675, FT-0639791, C14753, D05992, AB01329960-02, 2,4-Dihydroxy-6-(6beta,10-dihydroxyundecyl]benzoic acid mu-lactone, beta-Zearalanol solution, 10 mug/mL in acetonitrile, analytical standard, (3S,7S)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10,11,12-decahydro-1H-benzo[c][1]oxacyclotetradecin-1-one, (7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one, 1H-2-Benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-, (3S,7S)-, 1H-2-Benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-, (3S-(3R*,7R*))

ID: 535

InChIKey: DXDRHHKMWQZJHT-FPYGCLRLSA-N
SMILES: C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 638278
synonyms found at PubChem are:
isoliquiritigenin, 961-29-5, 2',4,4'-Trihydroxychalcone, 4,2',4'-Trihydroxychalcone, 6'-deoxychalcone, (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one, 2',4',4-Trihydroxychalcone, isoliquirtigenin, UNII-B9CTI9GB8F, GU 17, GU-17, CCRIS 7676, Chalcone, 2',4,4'-trihydroxy-, C15H12O4, EINECS 237-316-5, B9CTI9GB8F, 42'4'-trihydroxychalcone, 1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, BRN 1914295, Acrylophenone, 2',4'-dihydroxy-3-(p-hydroxyphenyl)-, CHEMBL129795, CHEBI:310312, DXDRHHKMWQZJHT-FPYGCLRLSA-N, (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one, (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 2-PROPEN-1-ONE, 1-(2,4-DIHYDROXYPHENYL)-3-(4-HYDROXYPHENYL)-, 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-, (2E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (E)-, 13745-20-5, Q-100904, (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone, SMR000112969, 1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one, SR-01000075499, iso-Liquiritigenin, Isoliquiritigenin/, ILTG, ISLQ, PubChem21917, Isoliquiritigenin, powder, Spectrum5_000612, AC1LCW23, Lopac0_000681, BSPBio_003411, 1-08-00-00707 (Beilstein Handbook Reference), MLS000438943, MLS002207240, MLS006010045, BIDD:ER0235, SCHEMBL161168, SPECTRUM1504200, BIFK0057, cid_638278, GU17, MEGxp0_001326, 2',4,4'-Trihydroxy-Chalcone, DTXSID2022466, 2'',4'',4-trihydroxychalcone, 2'',4,4''-trihydroxychalcone, ACon1_000047, CHEBI:94010, MolPort-001-741-660, BCPP000201, HMS2233H18, HMS3262I03, trans-2',4,4'-trihydroxychalcone, 2,4''-dihydroxy-4-hydroxychalcone, BCP02312, HY-N0102, ZINC3869608, Tox21_500681, ABP000708, BDBM50042944, CCG-40334, CI-098, CI0036, CMLD3_000056, GP4188, LMPK12120096, MFCD00075907, s2404, SBB066136, 2',4,4'-Trihydroxychalcone, 97%, Isoliquiritigenin, analytical standard, AKOS001590146, BCP9000795, CS-1745, DB03285, KS-5256, LP00681, MCULE-1557671934, SDCCGMLS-0066751.P001, NCGC00090504-01, NCGC00090504-02, NCGC00090504-03, NCGC00090504-04, NCGC00090504-05, NCGC00090504-06, NCGC00090504-07, NCGC00090504-08, NCGC00261366-01, AJ-46320, AK160201, AN-48170, CC-29647, KB-52784, LS-52925, O271, ST081356, AB0000350, AX8035519, LS-123872, EU-0100681, I0822, N1288, ST24047435, C08650, I 3766, M-1539, 961I295, A845551, NCGC00090504-04!2',4,4'-Trihydroxychalcone, 2',4'-Dihydroxy-3-(p-hydroxyphenyl)-Acrylophenone, I06-0544, SR-01000075499-1, SR-01000075499-5, BRD-K33583600-001-03-9, BRD-K33583600-001-04-7, 1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone, 1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one, (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one, (E)-1-[2,4-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one, 2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-, 4,2 inverted exclamation marka,4 inverted exclamation marka-Trihydroxychalcone, 1060-19-1, InChI=1/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3

ID: 536

InChIKey: DXGLGDHPHMLXJC-UHFFFAOYSA-N
SMILES: COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4632
synonyms found at PubChem are:
oxybenzone, 131-57-7, 2-HYDROXY-4-METHOXYBENZOPHENONE, Benzophenone-3, Oxybenzon, 4-Methoxy-2-hydroxybenzophenone, 2-Benzoyl-5-methoxyphenol, Oxibenzona, Oxybenzonum, (2-hydroxy-4-methoxyphenyl)(phenyl)methanone, Anuvex, Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-, Chimassorb 90, Uvinul 9, Advastab 45, Cyasorb UV 9, Sunscreen UV-15, Syntase 62, Uvistat 24, Usaf cy-9, Escalol 567, Spectra-sorb UV 9, Ongrostab HMB, Oxybenzonum [INN-Latin], Uvinul M40, Oxibenzona [INN-Spanish], Oxibenzonum, HMBP, Cyasorb UV 9 Light Absorber, (2-Hydroxy-4-methoxyphenyl)phenylmethanone, UF 3, UV 9, NSC-7778, Benzophenone, 2-hydroxy-4-methoxy-, DuraScreen, NCI-C60957, UNII-95OOS7VE0Y, CCRIS 1078, Uvinul M 40, CHEBI:34283, 2-hydroxy-4-methoxy benzophenone, HSDB 4503, NSC 7778, EINECS 205-031-5, BRN 1913145, 95OOS7VE0Y, CHEMBL1625, AI3-23644, (2-hydroxy-4-methoxyphenyl)-phenylmethanone, MOB, (2-hydroxy-4-methoxy-phenyl)-phenyl-methanone, NSC7778, DXGLGDHPHMLXJC-UHFFFAOYSA-N, NCGC00016394-07, CAS-131-57-7, 4-Methoxy-2-hydroxybenzophenone butyric acid, DSSTox_CID_2405, DSSTox_RID_76576, DSSTox_GSID_22405, 2-HYDROXY-4-METHOXYBENZOPHENONE (OXYBENZONE), 2-hydroxy-4-methoxyphenyl phenyl ketone, SMR000035344, SR-01000610567, Oxybenzone [USAN:USP:INN], Benzophenone 3, Neo heliopan BB, Kopben-3, PubChem3274, Solaquin (Salt/Mix), Spectrum_001049, DuraScreen (Salt/Mix), ACMC-1BVPH, KAHSCREEN BZ-3, AC1L1ILP, Prestwick0_000887, Prestwick1_000887, Prestwick2_000887, Prestwick3_000887, Spectrum2_001008, Spectrum3_000538, Spectrum4_000463, Spectrum5_001337, Benzophenone-3 (Bp-3), PreSun 15 (Salt/Mix), D02CWR, Epitope ID:131795, WLN: 1OR CQ DVR, EC 205-031-5, Oprea1_174131, SCHEMBL15551, BSPBio_000674, BSPBio_002155, KBioGR_000906, KBioSS_001529, KSC174M0J, MLS000039797, MLS001055487, BIDD:ER0353, DivK1c_000184, SPECTRUM1500451, SPBio_001135, SPBio_002893, Oxybenzone, analytical standard, BPBio1_000742, DTXSID3022405, CTK0H4604, HMS500J06, KBio1_000184, KBio2_001529, KBio2_004097, KBio2_006665, KBio3_001655, MolPort-001-760-048, NINDS_000184, HMS1570B16, HMS1920D16, HMS2091L16, HMS2097B16, HMS2424P09, HMS3714B16, Pharmakon1600-01500451, ZINC136138, ALBB-021277, BCP25880, HY-A0067, Tox21_110418, Tox21_201985, Tox21_302852, ANW-19363, BBL003220, BDBM50253134, CCG-40226, component of Presun 23 (Salt/Mix), component of Presun 29 (Salt/Mix), component of Presun 30 (Salt/Mix), LS-742, MFCD00008387, NSC757260, s4691, SBB056669, STK057962, AKOS000120532, Tox21_110418_1, 2-Hydroxy-4-methoxybenzophenone, 98%, CS-3186, DB01428, MCULE-2222013605, NSC-757260, RL01485, RTR-004325, TRA0043295, IDI1_000184, NCGC00016394-01, NCGC00016394-02, NCGC00016394-03, NCGC00016394-04, NCGC00016394-05, NCGC00016394-06, NCGC00016394-08, NCGC00016394-10, NCGC00065306-03, NCGC00065306-04, NCGC00065306-05, NCGC00065306-06, NCGC00256323-01, NCGC00259534-01, AC-11987, AJ-12292, AN-23061, AS-13616, CJ-01030, I956, ST029243, ZB004802, SBI-0051470.P003, KB-173071, KB-193020, ST2407894, TR-004325, AB00052063, FT-0612546, H2437, 2-Hydroxy-4-methoxybenzophenone, 98% 50g, (2-hydroxy-4-methoxyphenyl)(phenyl) methanone, C14285, D05309, AB00052063_13, AE-848/01549044, I01-3099, Q-200287, SR-01000610567-2, SR-01000610567-4, BRD-K59037100-001-05-5, BRD-K59037100-001-09-7, component of Caraloe snow & sun lip balm (Salt/Mix), Z1945708085, Oxybenzone, United States Pharmacopeia (USP) Reference Standard, 2-Hydroxy-4-methoxybenzophenone, certified reference material, TraceCERT(R), Oxybenzone, Pharmaceutical Secondary Standard; Certified Reference Material, 1-(cyclopropylcarbonyl)-N-(4-ethoxyphenyl)-3,3-dimethylindoline-5-sulfonamide, 2-Hydroxy-4-methoxybenzophenone (Neo Heliopan BB) 10 microg/mL in Cyclohexane, 138464-23-0, 14375-37-2, 153859-73-5, 58392-15-7, 58392-22-6, 897050-18-9, InChI=1/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H

ID: 537

InChIKey: DXVJRTIPBNBLLB-BJMVGYQFSA-N
SMILES: C1=CC(=CC=C1/C=C(\C#N)/C(=C(C#N)C#N)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5328804
synonyms found at PubChem are:
Tyrphostin AG 112, Tyrphostin A48, AG 112, ag112, AG-112, 2-Amino-4-(4′-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin-48, Tyrphostin Ag-112, AC1NS5DP, Lopac-T-6943, D02KVB, Lopac0_001140, CHEMBL76589, GTPL5913, SCHEMBL10144540, CHEBI:93930, HMS3229M17, HMS3263D21, 144978-82-5, Tox21_501140, HSCI1_000156, ZINC15977019, CCG-205214, LP01140, NCGC00016041-01, NCGC00016041-02, NCGC00016041-03, NCGC00016041-04, NCGC00094406-01, NCGC00094406-02, NCGC00261825-01, EU-0101140, T 6943, SR-01000076168, J-008034, SR-01000076168-1, BRD-K01192156-001-01-9, 2-amino-4-(4'-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene, 3-Amino-2,4-dicyano-5-(4'-hydroxyphenyl)-penta-2,4-dienonitrile, (3Z)-2-Amino-4-(4-hydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile, (3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile, 3-Amino-2,4-dicyano-5-(4 inverted exclamation marka-hydroxyphenyl)penta-2,4-dienonitrile

ID: 538

InChIKey: DYAYBCFQSRNPME-UHFFFAOYSA-N
SMILES: C(C1=CC=C([NH0+]([OH0-])=O)S1)1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "M Zacchigna" "LJ Galietta" "F Cateni" "M Giampieri" "MT Mazzei" "N Pedemonte" "M Mazzei"

CID is 15225370
synonyms found at PubChem are:
CHEMBL594332, SCHEMBL11686041

ID: 539

InChIKey: DYDCUQKUCUHJBH-UWTATZPHSA-N
SMILES: C1[C@H](C(=O)NO1)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6234
synonyms found at PubChem are:
D-cycloserine, cycloserine, 68-41-7, Seromycin, orientomycin, Oxamycin, Cyclorin, Cyclo-D-serine, Cicloserina, Farmiserina, Miroseryn, Tisomycin, Wasserina, Closina, D-4-amino-3-isoxazolidinone, (R)-4-AMINOISOXAZOLIDIN-3-ONE, alpha-Cycloserine, (+)-4-Amino-3-isoxazolidinone, Cycloserinum, Miroserina, D-4-amino-3-isoxazolidone, Oxamicina, PA 94, (+)-Cycloserine, (4R)-4-amino-1,2-oxazolidin-3-one, Oxamicina [Italian], Cycloserin, Micoserina, (4R)-4-aminoisoxazolidin-3-one, Cicloserina [Italian], PA-94, Tebemicina, Novoserin, D-Oxamycin, D-CS, Cycloserinum [INN-Latin], E-733-A, Cicloserina [INN-Spanish], (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, D-4-Amino-3-isossazolidone, D-(+)-Cycloserine, RO-1-9213, 3-Isoxazolidinone, 4-amino-, (R)-, Closerin, HSDB 3218, D-Oxamicina, 3-Isoxazolidinone, 4-amino-, d-, (R)-Cycloserine, K-300, Seromycin (TN), UNII-95IK5KI84Z, R-4-Amino-3-isoxazolidinone, Cycloserine [INN:BAN:JAN], I-1431, 3-Isoxazolidinone, 4-amino-, (+)-, D-4-Amino-3-isossazolidone [Italian], NSC 154851, 3-Isoxazolidinone, 4-amino-, (4R)-, R-(+)-Cycloserine, (R)-4-Amino-3-isoxazolidinone, CHEBI:40009, AI3-50153, (4R)-4-Amino-3-isoxazolidinone, D-Cycloserine, synthetic, DRG-0195, (R)-(+)-Cycloserine, EINECS 200-688-4, D-amino-3-isoxazolidinone, CHEMBL771, BRN 0080798, SC-49088, (R)-4-Amino-3-isoxazolidone, 95IK5KI84Z, 3-Isoxazolidinone, 4-amino-, D, DYDCUQKUCUHJBH-UWTATZPHSA-N, R(+)-4-Amino-3-isoxazolidinone, 3-Isoxazolidinone, 4-amino-, (R), (R)-(+)-4-Amino-3-isoxazolidinone, CAS-68-41-7, NCGC00016306-01, DSSTox_CID_2870, 3-Isoxazolidinone, 4-amino-, (+)- (8CI), 3-Isoxazolidinone, 4-amino-, (4R)- (9CI), C 3909, C-9390, C-9400, DSSTox_RID_76766, DSSTox_GSID_22870, FA6C7F8B-D080-4EA3-978F-1ECFB5A29D09, Cycloserine (JP15/USP/INN), Cycloserine, D-, .alpha.-Cycloserine, 4AX, CPD000058313, SMR000058313, (S)-(-)-Cycloserine, 3-Isoxazolidinone, 4-amino-, (+)-(8CI), 3-isoxazolidinone, 4-amino-, (4r)-(9ci), 4-Amino-isoxazolidin-3-one, SR-01000075432, D-Cycloserine synth. BP 88, Serine, cyclo-, Cycloserine [USP:INN:BAN:JAN], PubChem5763, D-Cycloserine, powder, Spectrum_000860, 1pb9, CYCLOSERINE (D), Prestwick0_001089, Prestwick1_001089, Prestwick2_001089, Prestwick3_001089, Spectrum2_000084, Spectrum3_000371, Spectrum4_000305, Spectrum5_000797, Lopac-C-1159, Lopac-C-3909, Lopac-C-7005, D02WFK, D04TMQ, D0G6RT, AC1Q4UA7, Lopac0_000252, SCHEMBL34322, BSPBio_001138, BSPBio_002121, KBioGR_000890, KBioSS_001340, 4-27-00-05549 (Beilstein Handbook Reference), MLS000758215, MLS001423962, MLS002548887, BIDD:GT0707, DivK1c_000098, SPECTRUM1500215, SPBio_000008, SPBio_003029, AC1L1M33, BPBio1_001252, GTPL9489, Cycloserine (JP17/USP/INN), 4-Amino-3-isoxazolidinone, D-, DTXSID8022870, HMS500E20, KBio1_000098, KBio2_001340, KBio2_003908, KBio2_006476, KBio3_001341, MolPort-000-858-643, NINDS_000098, HMS1571I20, HMS1920C06, HMS2051C15, HMS2091I14, HMS2098I20, HMS2232F03, HMS3259L19, HMS3260D06, HMS3715I14, NJ-21, Pharmakon1600-01500215, R (+)-4-amino-3-isoxazolidinone, (R)-3-Isoxazolidinone, 4-amino-, 4-Amino-3-isoxazolidinone, (R)-, ACT04767, HY-B0030, KS-00001FB7, Tox21_110361, Tox21_500252, BDBM50038178, BDBM50103516, CCG-39705, D-Cycloserine, >=96.0% (NT), FC1270, LMPK14000007, MFCD00005353, NSC756712, s1998, ZINC34676245, (R)-4-amino-1,2-oxazolidin-3-one, 4-Isoxazolidinamine, 3-oxo-, (D)-, AKOS015994626, Tox21_110361_1, AC-4721, CS-2395, DB00260, HS-0079, LP00252, MCULE-4212827696, NC00050, NC00676, NSC-756712, RL04615, IDI1_000098, SMP1_000167, NCGC00015213-01, NCGC00015213-02, NCGC00015213-03, NCGC00016306-02, NCGC00016306-03, NCGC00016306-04, NCGC00016306-05, NCGC00016306-07, NCGC00016306-08, NCGC00093713-01, NCGC00093713-02, NCGC00260937-01, AJ-89953, AN-11678, BR-26256, CAS-339-72-0, K138, KB-49618, LS-86757, SAM001247014, SAM002264599, SC-06256, ST075697, SBI-0050240.P004, AB0007232, AB2000415, ST2408171, AB00443920, EU-0100252, FT-0624464, (4R)-4-amino-2,4,5-trihydroisoxazol-3-one, C08057, D00877, AB00443920_09, AB00443920_10, 005C353, 101039-EP2295402A2, 101039-EP2301544A1, SR-01000759389, SR-01000075432-1, SR-01000075432-2, SR-01000075432-5, SR-01000075432-9, SR-01000759389-4, SR-01000075432-10, F2173-1228, Z1522567171, Cycloserine, United States Pharmacopeia (USP) Reference Standard, Cycloserine, Pharmaceutical Secondary Standard; Certified Reference Material, cycloserine zwitterion, D-cycloserine zwitterion, alpha-cycloserine zwitterion, CHEBI:74159, D-4-amino-3-isoxazolidinone zwitterion, CJ-18543, (+)-4-amino-3-isoxazolidinone zwitterion, (4R)-4-aminoisoxazolidin-3-one zwitterion, (4R)-4-ammonio-4,5-dihydroisoxazol-3-olate, (4R)-4-ammonio-3-oxo-1,2-oxazolidin-2-ide, A836140, (4R)-4-azaniumyl-4,5-dihydro-1,2-oxazol-3-olate

ID: 540

InChIKey: DYEFUKCXAQOFHX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3194
synonyms found at PubChem are:
ebselen, 60940-34-3, 2-Phenyl-1,2-benzisoselenazol-3(2H)-one, Ebselene, Ebseleno, Ebselenum, 2-phenyl-1,2-benzoselenazol-3-one, Ebselene [French], Ebselenum [Latin], Ebselen [INN], Ebseleno [Spanish], PZ 51, 2-phenylbenzo[d][1,2]selenazol-3(2H)-one, Harmokisane, SPI-1005, C13H9NOSe, MLS000028488, UNII-40X2P7DPGH, PZ-51, CCRIS 3714, PZ51, DR-3305, 2-Phenyl-1,2-benzisoselenazolin-3-one, SMR000058445, 2-phenyl-1,2-benzoisoselenazol-3(2H)-one, 1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-, CHEMBL51085, NSC 639762, DR 3305, Prestwick_1057, RP 60931, SPI-3005, AC1L1FDW, Prestwick0_000740, Prestwick1_000740, Prestwick2_000740, Prestwick3_000740, Spectrum2_001441, Spectrum3_000799, Spectrum4_000445, Spectrum5_001713, Lopac-E-3520, NSC639762, 40X2P7DPGH, Lopac0_000541, NCGC00015412-06, BSPBio_000700, BSPBio_001342, BSPBio_002538, CPD000058445, KBioGR_000062, KBioGR_000830, KBioSS_000062, DivK1c_000951, SPBio_001301, SPBio_002639, CAS-60940-34-3, MLS001148646, BPBio1_000770, BCBcMAP01_000149, CHEBI:77543, HMS502P13, KBio1_000951, KBio2_000062, KBio2_002630, KBio2_005198, KBio3_000123, KBio3_000124, KBio3_001758, NINDS_000951, DYEFUKCXAQOFHX-UHFFFAOYSA-N, E 3520, Bio2_000062, Bio2_000542, HMS1361D04, HMS1570C22, HMS1791D04, HMS1989D04, HMS2052N09, AC-1124, IDI1_000951, IDI1_033812, QTL1_000035, NCGC00015412-01, NCGC00015412-02, NCGC00015412-03, NCGC00015412-13, NCGC00024072-03, NCGC00024072-04, NCGC00024072-05, NCGC00178610-01, NCGC00178610-02, NCGC00178610-03, 2-phenyl-1,2-benzoselenazol-3(2h)-one, LS-33527, SAM001247071, AB00053217, EU-0100541, MLS-0003066.0001, BRD-K29359156-001-06-1, I09-1611, SR-01000003081, CID3194, Ebselen (C5), nchembio.109-comp1, Opera_ID_1643, Ebselen, cysteine modifier, D0B1FE, cid_3194, DSSTox_CID_25150, DSSTox_RID_80704, C042986, DSSTox_GSID_45150, SCHEMBL33829, MLS001424261, MLS006010108, E3520_SIGMA, DTXSID7045150, BDBM34233, CTK7H1817, CHEBI:175507, MolPort-003-666-383, HMS2097C22, HMS2235A11, HMS3394N09, HMS3402D04, HMS3649O05, HMS3714C22, KUC112559N, Pharmakon1600-01501188, BCP17134, EX-A1447, KS-00000G4G, Tox21_110140, 2-Phenyl-benzo[d]isoselenazol-3-one, BN0569, CCG-39161, DAP001372, DR3305, GP4285, MFCD00210937, NSC757883, AKOS015898841, API0002512, CS-5534, DB12610, LP00541, NC00431, NSC-639762, NSC-757883, TRA0091838, KSC-325-014, NCGC00015412-04, NCGC00015412-05, NCGC00015412-07, NCGC00015412-08, NCGC00015412-09, NCGC00015412-10, NCGC00015412-11, NCGC00015412-12, phenyl-1,2-benzisoselenazol-3(2H)-one, 2-phenyl-1,2-benzisoselazol-3(2H)-one, AK115695, AN-15216, BC224294, HY-13750, SBI-0050524.P003, 2-phenyl-1,2-benzisoselenazole-3(2H)-one, AB0020911, AX8127093, DB-072873, 2-phenyl-1,2-benzoisoselenazole-3(2H)-one, E0946, FT-0759332, V1941, 2-phenyl-1,2-benzoisoselenazole-3-(2H)-one, 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen), AB00053217_25, 940E343, SR-01000003081-2, SR-01000003081-7, SR-01000003081-8, BRD-K29359156-001-23-6, SR-01000003081-10, SR-01000003081-14

ID: 541

InChIKey: DYJVZTAMQYDCLP-VCSAJMHUSA-N
SMILES: CC(C)N1C=C2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)OC(C)C(C)O)C4=C2C1=CC=C4.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6437377
synonyms found at PubChem are:
Lilly 53857, LY 53857, LY-53857, LY-53,857 maleate, Ergoline-8-carboxylic acid, 6-methyl-1-(1-methylethyl)-, 2-hydroxy-1-methylpropyl ester, (8beta)-, (Z)-2-butenedioate (1:1) (salt), 60634-51-7, C23H32N2O3.C4H4O4, LY 53,857, SCHEMBL2970215, 6-Methyl-1-(1-methylethyl)-, CHEMBL1399645, NCGC00094069-01, LS-176115, EU-0100721, L-107, SR-01000075553, SR-01000075553-1, ergoline-8beta-carboxylic acid 2-hydroxy-1-methylpropyl ester maleate

ID: 542

InChIKey: DYOZWAJOUTVNAF-UHFFFAOYSA-N
SMILES: CNCCC1=CNC2=C1C=C(C=C2)O.C(=O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 260390
synonyms found at PubChem are:
3-(2-Methylaminoethyl)indol-5-ol oxalate, 15558-50-6, 1975-81-1, N-omega-Methylserotonin, N-omega-Methyl-5-hydroxytryptamine oxalate salt, H-7000, Nomega-Methyl-5-hydroxy-trypt-amine oxalate salt, NSC91541, EINECS 239-611-4, 5-hydroxy-nw-methyltryptamine oxalate, AC1Q5RMG, N-Methylserotonin oxalate, MLS000859941, SCHEMBL1320479, CHEMBL1256286, CTK0I2793, N|O-Methylserotonin oxalate salt, DTXSID80293695, HMS2234N19, HMS3262E08, HMS3371J12, Nomega-Methylserotonin oxalate salt, AC1L6327, N-Omega-methylserotonin oxalate salt, Tox21_500743, MFCD00013159, NSC-91541, AKOS024282337, 5-Hydroxy-N|O-methyltryptamine oxalate, ACM1975811, CCG-222047, LP00743, MCULE-1823155663, N-omega-METHYL-5-HYDROXYTRYPTAMINE, NCGC00094085-01, NCGC00261428-01, 5-Hydroxy-Nomega-methyltryptamine oxalate, SMR000326801, ST055634, EU-0100743, FT-0620492, M 1514, N|O-Methyl-5-hydroxy-trypt-amine oxalate salt, 5-Hydroxy-N-omega-methyltryptamine, oxalate salt, 5-Hydroxy-Nomega-methyltryptamine oxalate, 99%, 3-(2-(Methylamino)ethyl)-1H-indol-5-ol oxalate, Nomega'-Methyl-5-hydroxy trypt amine oxalate salt, SR-01000075980, J-012764, SR-01000075980-1, 3-[2-(methylamino)ethyl]indol-5-ol, ethanedioic acid, 3-[2-(methylamino)ethyl]-1H-indol-5-ol; oxalic acid, 1H-Indol-5-ol,3-[2-(methylamino)ethyl]-,ethanedioate(1:1), Nomega-Methyl-5-hydroxy??trypt??amine oxalate salt, >=98% (alkalimetric)

ID: 543

InChIKey: DYYZXRCFCVDSKD-UHFFFAOYSA-N
SMILES: CN(C)C1=NC=C2C(=C1)C(=NC=N2)NC3=CC4=C(C=C3)N(N=C4)CC5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603857
synonyms found at PubChem are:
GW2974, 202272-68-2, CHEMBL30432, GW282974X, N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido-[3,4-d]-pyrimidine-4,6-diamine, Lopac-G-0668, AC1O7G3B, Lopac0_000509, SCHEMBL1737530, CHEBI:95273, CTK8E8381, DTXSID40424963, DYYZXRCFCVDSKD-UHFFFAOYSA-N, HMS3261F19, HMS3303J07, HMS3305C14, Tox21_500509, BDBM50099963, GW-974, MFCD04974495, ZINC18371391, CCG-204600, LP00509, KS-0000183M, SMP2_000268, SMP2_000301, NCGC00015468-01, NCGC00015468-02, NCGC00015468-03, NCGC00015468-04, NCGC00015468-05, NCGC00015468-06, NCGC00093907-01, NCGC00093907-02, NCGC00261194-01, GW2974, >=98% (HPLC), solid, RT-013147, EU-0100509, G 0668, AB01092265-01, SR-01000075892, J-013131, SR-01000075892-1, 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine, N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*,N*6*-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine, N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine, N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido[3,4-d]pyrimidine4-4,6-diamine

ID: 544

InChIKey: DZZGIXHAFVXSKV-UHFFFAOYSA-N
SMILES: CC1=C(C=CC(=C1C)S(=O)(=O)N2C=CN=C2C)OC

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"AB Wood" "JM Knapp" "GL Lukacs" "B Yang" "AS Verkman" "MJ Kurth" "PW Phuan"

CID is 1094932
synonyms found at PubChem are:
801224-90-8, BAS 09620936, F1696-0184, 1-(4-methoxy-2,3-dimethylphenyl)sulfonyl-2-methylimidazole, 1-((4-methoxy-2,3-dimethylphenyl)sulfonyl)-2-methyl-1H-imidazole, 1-(4-Methoxy-2,3-dimethyl-benzenesulfonyl)-2-methyl-1H-imidazole, AC1LM1YZ, MLS001202930, CHEMBL1360496, DZZGIXHAFVXSKV-UHFFFAOYSA-N, MolPort-002-015-475, HMS2833P13, ZINC816467, AKOS002286101, MCULE-7772630708, SMR000524602, ST50287774, AP-263/42610970, SR-01000367214, SR-01000367214-1, Z57705542, 1-[(4-methoxy-2,3-dimethylphenyl)sulfonyl]-2-methylimidazole, 1-(4-methoxy-2,3-dimethylbenzenesulfonyl)-2-methyl-1H-imidazole, 2,3-dimethyl-4-[(2-methyl-1H-imidazol-1-yl)sulfonyl]phenyl methyl ether

ID: 545

InChIKey: FACUYWPMDKTVFU-BYPYZUCNSA-N
SMILES: C1=CN(C(=O)NC1=O)C[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 440053
synonyms found at PubChem are:
(S)-WILLARDIINE, Willardiine, 21416-43-3, S(-)-Willardiine, 3-(Uracil-1-yl)-L-alanine, (-)-Willardiine, CHEMBL122005, CHEBI:15851, HWD, 3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, 1mqj, D04SMQ, 3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)alanine, AC1L98KY, Lopac0_001219, SCHEMBL401191, SCHEMBL13319907, BDBM17661, CTK5H8581, MolPort-003-959-938, ZINC901774, 96108-98-4, 2990AH, AKOS006281897, CCG-205293, CS-3618, DB04129, NCGC00094464-03, HY-12499, EU-0101219, W-105, C03584, (2S)-2-amino-3-(2,4-dioxopyrimidin-1-yl)propanoic acid, (S)-2-Amino-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid, 2-amino-3-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)propionic acid, S(-)-|A-Amino--3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid, S(-)-alpha-Amino-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid, (2S)-2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid, L-willardiine, CHEBI:57543, 3-(uracil-1-yl)-L-alanine zwitterion, ZB015307, (2S)-2-azaniumyl-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoate, (2S)-2-azaniumyl-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoate

ID: 546

InChIKey: FAEKWTJYAYMJKF-QHCPKHFHSA-N
SMILES: CCOC1=C(C=CC(=C1)CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 65981
synonyms found at PubChem are:
Repaglinide, 135062-02-1, Prandin, NovoNorm, GlucoNorm, AG-EE 623 ZW, Repaglinidum, Repaglinida, Repaglinidum [INN-Latin], Repaglinida [INN-Spanish], AG-EE 388 ZW, (S)-2-Ethoxy-4-(2-((3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid, AGEE-623ZW, Repaglinide [USAN], Actulin, Surepost, Prandin (TN), UNII-668Z8C33LU, AG-EE 388, CHEMBL1272, Repaglinide (JAN/USP/INN), (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid, AG-EE-623 ZW, CHEBI:8805, AG-EE-388, SMP-508, 668Z8C33LU, C27H36N2O4, NN-623, (S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)phenyl)butylamino)-2-oxoethyl)benzoic acid, 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid, 2-Ethoxy-4-[2-[[(1S)-3-Methyl-1-[2-(1-Piperidinyl)Phenyl]Butyl]Amino]-2-Oxoethyl]Benzoic Acid, NCGC00016978-01, 111GE012, CAS-135062-02-1, (+)-2-Ethoxy-alpha-(((S)-alpha-isobutyl-o-piperidinobenzyl)carbamoyl)-p-toluic acid, (S)-2-Ethoxy-4-(2-((methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-benzoic acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid, 2-ethoxy-N-(alpha-(2-methyl-1-propyl)-2-piperidinobenzyl)-4-carbamoylmethylbenzoic acid, (S)-2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)-phenyl)butyl)amino)-2-oxoethyl)-benzoic acid, Q-201663, (-)-Repaglinide, Reglin, repa-glinide, 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid, 2-ethoxy-4-(2-{[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino}-2-oxoethyl)benzoic acid, 2-ethoxy-4-[2-({(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid, Benzoic acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)-2-oxoethyl)-, (S)-, SMR000466305, repaglinide, (+-)-isomer, enyglid, (S)-Repaglinide, Repaglinide,(S), GlucoNorm (TN), Surepost (TN), (S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid, Repaglinide [USAN:USP:INN:BAN], NovoNorm (TN), (S)-(+)-Repaglinide, AC1Q5TZW, Prestwick0_001046, Prestwick1_001046, Prestwick2_001046, Prestwick3_001046, DSSTox_CID_3552, Prandin;GlucoNorm;NovoNorm, D0N5YA, DSSTox_RID_77078, DSSTox_GSID_23552, SCHEMBL16137, BSPBio_000972, MLS000759407, MLS001076684, MLS001424111, MLS006011560, AG-EE 623ZW, BIDD:GT0338, SPBio_002906, AC1L24D5, BPBio1_001070, GTPL6841, DTXSID3023552, CTK3J7345, Novo Nordisk brand of repaglinide, FAEKWTJYAYMJKF-QHCPKHFHSA-N, MolPort-003-850-140, HMS1571A14, HMS2051N08, HMS2094C07, HMS2098A14, HMS2231M21, HMS3715A14, Pharmakon1600-01506035, Glaxo Wellcome brand of replaginide, BCP04250, KS-00000GU9, ZINC3798537, Novo Nordisk brand 2 of repaglinide, Tox21_110721, AC-726, ANW-63956, BDBM50153520, BG0514, MFCD00906179, NSC759893, s1426, STK629501, AKOS005561792, Repaglinide, >=98% (HPLC), solid, API0004049, BS-1010, CCG-101013, CS-0979, DB00912, MCULE-3611790330, NC00263, NSC-759893, RTC-063882, NCGC00016978-02, NCGC00016978-04, NCGC00016978-05, AJ-45642, AK-59609, AN-15576, BC220160, CC-34234, CPD000466305, HY-15209, I979, LS-38509, SAM001246546, SC-17344, Prandin, GlucoNorm, NovoNorm, Repaglinide, SBI-0206942.P001, AB0013959, AB2000099, AX8145505, TC-063882, AB00514019, AM20090697, FT-0631150, R0179, ST24036034, 62R021, C07670, D00594, W-5210, AB00514019-09, AB00514019_10, AB00514019_11, C-22512, SR-01000759404, SR-01000759404-4, BRD-K82846253-001-03-0, Z1777729210, Repaglinide, European Pharmacopoeia (EP) Reference Standard, Repaglinide, United States Pharmacopeia (USP) Reference Standard, (s)-(+)-2-ethoxy-4-(2-oxo-2-[(alpha-isobutyl-2-piperidinobenzyl)amino]ethyl)-benzoic acid, Repaglinide for system suitability, European Pharmacopoeia (EP) Reference Standard, (S)-2-Ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoic acid, 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid, 2-Ethoxy-4-{[(S)-3-methyl-1-(2-piperidin-1-yl-phenyl)-butylcarbamoyl]-methyl}-benzoic acid, Benzoic acid, 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-

ID: 547

InChIKey: FAKRSMQSSFJEIM-RQJHMYQMSA-N
SMILES: C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 44093
synonyms found at PubChem are:
captopril, 62571-86-2, Capoten, L-Captopril, Captopryl, Lopirin, Cesplon, Captolane, Tensoprel, Acepress, Captoril, Dilabar, Garranil, Hypertil, Tenosbon, Alopresin, Captoprilum, Acepril, Lopril, Acediur, Aceplus, Isopresol, Tensobon, Apopril, Asisten, Captoprilum [INN-Latin], D-2-Methyl-3-mercaptopropanoyl-L-proline, (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid, SQ-14225, Hipertil, Lopirin [Switzerland], D-3-Mercapto-2-methylpropanoyl-L-proline, SQ 14225, (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline, 1-((2S)-3-Mercapto-2-methylpropionyl)-L-proline, SQ 14,225, SA 333, D-3-Mercapto-2-methylpropionylproline, Captril, Tensiomin, UNII-9G64RSX1XD, 3-Mercapto-2-methylpropionyl-proline, (-)-Captopril, Apopril (TN), Capoten (TN), 1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, CHEBI:3380, (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, HSDB 6527, Captopril [USAN:INN:BAN:JAN], Garranil (discontinued), EINECS 263-607-1, 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline, 9G64RSX1XD, CHEMBL1560, 1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-L-proline, C9H15NO3S, MLS000069484, 1-(D-3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S,S), L-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-, L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-, FAKRSMQSSFJEIM-RQJHMYQMSA-N, N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline, [2S]-1-[3-Mercapto-2-methylpropionyl]-L-proline, MFCD00168073, NCGC00023654-04, SMR000059061, SQ-14534, SQ-14,225, SQ-14,534, C 4042, 1-Pyrrolidinecarboxylic acid, 1-(D-3-mercapto-2-methyl-1-propionyl)-, L-(S,S)-, DSSTox_CID_17197, DSSTox_RID_79306, DSSTox_GSID_37197, (S)-1-(3-Mercapto-2-methyl-1-oxo-propyl)-L-proline, L-Proline, 1-((2S)-3-mercapto-2-methyl-1-oxopropyl)-, Novocaptopril, Farcopril, Hypopress, Zapto, Captopril (Capoten), (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid, Capozide (Salt/Mix), X8Z, 1-[(2s)-3-mercapto-2-methylpropionyl]-l-proline, SR-01000075603, component of Captea (Salt/Mix), component of Acezide (Salt/Mix), component of Ecazide (Salt/Mix), S-Captopril, (2S)-1-((2S)-2-methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid, Captopril,(S), Prestwick_103, Captopril [USAN:USP:INN:BAN:JAN], SCHEMBL4, Spectrum_000688, Opera_ID_1041, Prestwick3_000019, Spectrum2_001211, Spectrum3_001388, Spectrum4_000811, Spectrum5_001587, Lopac-C-4042, 1-((2S)-2-Methyl-3-sulfanylpropanoyl)-L-proline #, D0I0EG, Epitope ID:114065, UPCMLD-DP003, AC1L2B4L, AC1Q29GZ, (S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline, Lopac0_000302, BSPBio_000057, BSPBio_002976, KBioGR_001321, KBioSS_001168, MLS001076488, DivK1c_000208, SPECTRUM1500682, SPBio_001022, Captopril (JP15/USP/INN), Captopril (JP17/USP/INN), AC1Q5R48, BPBio1_000063, GTPL5158, DTXSID1037197, UPCMLD-DP003:001, BDBM21642, HMS500K10, KBio1_000208, KBio2_001168, KBio2_003736, KBio2_006304, KBio3_002196, KS-00000XHT, ZINC57001, 1j37, MolPort-001-794-639, NINDS_000208, HMS1921C12, HMS2089P19, HMS2092I12, HMS2095C19, HMS2233I04, HMS3259G10, HMS3260N06, HMS3712C19, Pharmakon1600-01500682, HY-B0368, MCO, Tox21_110890, Tox21_500302, BBL033600, CCG-39104, EI-213, KM0635, NSC757419, s2051, SBB017523, STK802012, AKOS005622581, Captopril, >=98% (HPLC), powder, Tox21_110890_1, AB04252, BCP9000485, CS-2425, DB01197, KS-5025, LP00302, MCULE-1716939647, NC00554, NSC-757419, SQ14225, SQ14534, IDI1_000208, SMP1_000056, NCGC00015235-01, NCGC00015235-02, NCGC00023654-03, NCGC00023654-05, NCGC00023654-06, NCGC00023654-07, NCGC00023654-08, NCGC00023654-09, NCGC00023654-10, NCGC00023654-11, NCGC00023654-13, NCGC00260987-01, AC-12047, BC203925, CPD000059061, SAM002564201, ST079562, SBI-0050290.P004, AB0007072, AB2000455, Captopril, meets USP testing specifications, LS-137465, EU-0100302, FT-0082749, ((S)-3-mercapto-2-methylpropanoyl)-L-proline, BIM-0050290.0001, C06867, D00251, J10167, 54254-EP2269989A1, 54254-EP2270011A1, 54254-EP2272841A1, 54254-EP2277879A1, 54254-EP2287165A2, 54254-EP2287166A2, 54254-EP2292620A2, 54254-EP2295406A1, 54254-EP2298742A1, 54254-EP2298772A1, 54254-EP2298776A1, 54254-EP2298779A1, 54254-EP2301923A1, 54254-EP2301931A1, 54254-EP2301936A1, 54254-EP2305219A1, 54254-EP2305648A1, 54254-EP2308562A2, 54254-EP2308839A1, AB00052156-16, AB00052156_17, AB00052156_18, 571C862, SR-01000000039, 1-[(2S)-3-Mercapto-2-methylpropionyl]- L-proline, SR-01000000039-2, SR-01000075603-1, SR-01000075603-3, 1-[(S)-3-mercapto-2-methyl-1-oxopropyl]-L-proline, BRD-K54529596-001-04-0, BRD-K54529596-001-15-6, Z2786051697, ([2S]-N-[3-MERCAPTO-2-METHYLPROPIONYL]-L-PROLINE, Captopril, European Pharmacopoeia (EP) Reference Standard, Captopril, United States Pharmacopeia (USP) Reference Standard, (S)-1-((S)-3-Mercapto-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid, Captopril, Pharmaceutical Secondary Standard; Certified Reference Material, L-?Proline, 1-?[(2S)?-?3-?mercapto-?2-?methyl-?1-?oxopropyl]?-, Captopril for system suitability, European Pharmacopoeia (EP) Reference Standard, 138452-88-7, 225661-74-5, 70903-77-4

ID: 548

InChIKey: FAOZLTXFLGPHNG-KNAQIMQKSA-N
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 9878
synonyms found at PubChem are:
fluorometholone, 426-13-1, Fluoromethalone, Oxylone, Flumetholon, Fluormetholone, FML Liquifilm, Fluor-Op, Cortilet, Delmeson, Trilcin, FML Forte, Fluorometolona, Fluorometholonum, Fluormetholon, Fluormetholonum, Fluorometolone, Efflumidex, Neo-Oxylone, Fluorometolone [DCIT], FML-S Liquifilm, Fluorometholonum [INN-Latin], Fluorometolona [INN-Spanish], NSC 33001, Fluorometholon, Fluaton, Loticort, Ursnon, component of Neo-Oxylone, UNII-SV0CSG527L, FML, Oxylone (TN), U 8614, Fluor-op (TN), CHEBI:31625, Fluorometholone [INN:BAN:JAN], Fml (TN), EINECS 207-041-5, (6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, FML S.O.P, SV0CSG527L, 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione, AI3-52813, MLS000069537, MLS001076157, NSC33001, 9-Fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione, SMR000058598, F0414, Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17-dihydroxy-6-alpha-methyl-, DSSTox_CID_27435, DSSTox_RID_82345, FML S.O.P., Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-, DSSTox_GSID_47435, Cortisdin, Fluoropos, Flucon, Fluoro Ophtal, Fluoro-Ophtal, Isopto Flucon, 11|A,17|A-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione, Flucon, Isopto, 11beta,17alpha-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione, Fluor Op, PMS Fluorometholone, PMS-Fluorometholone, 9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione, flumetholone, NSC-33001, NCGC00016442-01, CAS-426-13-1, Prestwick_227, Fluorometholone [USP:INN:BAN:JAN], Opera_ID_341, Prestwick0_000718, Prestwick1_000718, Prestwick2_000718, Prestwick3_000718, Fluorometholone, >=98%, D0P0HT, AC1L1U0Y, SCHEMBL5051, BSPBio_000935, Alcon Brand of Fluorometholone, Isdin Brand of Fluorometholone, SPBio_002856, BPBio1_001029, GTPL7079, Winzer Brand of Fluorometholone, CHEMBL1200600, DTXSID7047435, Novartis Brand of Fluorometholone, MolPort-003-941-413, Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methyl-, Ursapharm Brand of Fluorometholone, Fluorometholone (JP15/USP/INN), Fluorometholone (JP17/USP/INN), HMS1570O17, HMS2097O17, HMS2234F16, HMS3714O17, Allergan Brand 1 of Fluorometholone, Allergan Brand 2 of Fluorometholone, Allergan Brand 3 of Fluorometholone, Tox21_110440, Tox21_302593, BDBM50103631, MFCD00056461, Pharmascience Brand of Fluorometholone, AKOS015895108, Tox21_110440_1, ZINC118912517, AC-3520, CCG-220718, DB00324, Pharm Allergan Brand of Fluorometholone, Pharm-Allergan Brand of Fluorometholone, NCGC00021575-03, NCGC00021575-05, NCGC00256631-01, AN-12858, AS-12363, CC-28503, NCI60_002886, SC-46978, AB2000748, LS-118455, FT-0603391, Progesterone, 17-dihydroxy-6.alpha.-methyl-, D01367, 426F131, C-21266, SR-01000003019, SR-01000003019-2, BRD-K64862097-001-03-9, BRD-K64862097-001-12-0, Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17, Fluorometholone, British Pharmacopoeia (BP) Reference Standard, Fluorometholone, United States Pharmacopeia (USP) Reference Standard, 11beta, 17alpha-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,-20-dione, Pregna-1,20-dione, 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methyl-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl-, Progesterone, 1-dehydro-9-fluoro-11.beta., 17-dihydroxy-6.alpha.-methyl-, (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione, Pregna-1,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6-alpha,11-beta)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl- (8CI), Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl-(8CI), (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-5-one, (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one, Pregna-1, 4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha., 11.beta.)-

ID: 549

InChIKey: FATOICABJMDCPU-LHTZQXJVSA-N
SMILES: C[C@@H]1CC[C@H]2[C@@H]([C@H]3CC[C@@H]4[C@H]([C@@H]3CN2C1)C[C@H]5[C@H]4C[C@H]([C@@H]6[C@@]5(CC[C@H](C6)OC(=O)C)C)OC(=O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 90470318
synonyms found at PubChem are:
21851-07-0, FATOICABJMDCPU-LHTZQXJVSA-N, ZINC100110559

ID: 550

InChIKey: FAVUCMGCKDICCE-UHFFFAOYSA-N
SMILES: C[N+]1(C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43)C.[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957728
synonyms found at PubChem are:
3-Tropanylindole-3-carboxylate methiodide, EU-0101273, MLS002153353, CHEMBL1456417, HMS2232A17, HMS3263P08, HMS3373N11, Tox21_501273, CCG-222577, LP01273, NCGC00261958-01, SMR001230758, SR-01000076183, SR-01000076183-1

ID: 551

InChIKey: FBOZXECLQNJBKD-UHFFFAOYSA-N
SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4112
synonyms found at PubChem are:
Amethopterin, DL-Amethopterin, (+)-Amethopterin, DL-Methotrexate, Methylaminopterin, 60388-53-6, TCMDC-123832, 6-Mtx (DL), Amethopterin (R,S), EINECS 262-213-7, METHOTREXATE(+/-), MLS002701970, N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-DL-glutamic acid, N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-DL-glutamic acid, NSC 117356, Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, DL-, L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, Emtexate, Folex, C19H23N9O4, C20H22N8O5, 2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid, DL-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, (+-)-Methotrexate, D(-)-AMETHOPTERIN, SR-05000001673, Methotrexate polyglutamate, FBOZXECLQNJBKD-UHFFFAOYSA-N, NSC117356, ( )Amethopterin, 2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]methylamino}phenyl)carbonylamino]pent anedioic acid, Prestwick_753, Folex (Salt/Mix), AC1L1HFS, Prestwick0_000373, Prestwick1_000373, Prestwick2_000373, Prestwick3_000135, Prestwick3_000373, Methotrexate, (+/-)-, CHEMBL426, AC1Q5SF6, Methotrexate, (DL)-Isomer, SCHEMBL3712, BSPBio_000210, BSPBio_000525, BSPBio_001993, ChEMBL_59579, METHOTREXATE, U.S.P., SPECTRUM1500398, SPBio_002446, BPBio1_000232, BPBio1_000579, Methotrexate pound>>Amethopterin, SCHEMBL11986730, CHEBI:93775, Kyselina N-(p-((2,4-diamino-6-pteridinylmethyl)methylamino)benzoyl)-L-glutamova, MolPort-001-779-666, HMS1569K07, HMS1920L21, HMS2091D16, HMS2096K07, HMS3267F07, HMS3371G08, HMS3403O03, HMS3654M22, HMS3713K07, Pharmakon1600-01500398, BCP02078, BDBM50004545, METHOTREXATE USP AND EP GRADE, NSC757113, AKOS000281496, AKOS024282621, 4-Amino-N10-methylpteroylglutamic acid, CCG-212689, MCULE-3234195945, NSC-117356, NSC-757113, NCGC00015079-03, NCGC00015079-04, NCGC00095284-01, NCGC00095284-02, 4CA-0097, 82334-40-5, AC-11680, AN-39412, L-4-Amino-N10-methylpteroylglutamic acid, LS-71811, NCI60_041622, Poly(imino(1-carboxy-4-oxo-1,4-butanediyl)), alpha-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-omega-hydroxy-, (S)-, SMR001565548, ST057254, ST069344, SBI-0053664.P003, AB0012834, Kyselina 4-amino-N10-methylpteroylglutamova, M1664, 388A536, I06-0203, SR-05000001673-1, SR-05000001673-2, BRD-A55424491-001-07-4, BRD-A55424491-001-08-2, I14-19311, (MTX)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid, 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid, 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid, 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid, 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(MTX), Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)-, N-(4-[[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino]benzoyl)glutamic acid, (L)-, N-(p-((2,4-Diamino-6-pteridyl)methyl)methylamino)benzoyl)glutamic acid, (L)-, (methotrexate)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid, (Methotrexate, MTX)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid, 184883-35-0, 2-[(4-{[(4-amino-2-imino-3H-pteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid, 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid (Methotrexate), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid (MTX), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid bis-adamantan-1-ylamide, 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(Amethopterin), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(Methotrexate (MTX)), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(Methotrexate ), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(methotrexate(MTX)), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(Methotrexate), 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(Methotrexate, MXT), 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(methotrexate, MTX), Methotrexate solution, 1.0 mg/mL in methanol with 0.1N NaOH, ampule of 1 mL, certified reference material, Methotrexate2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid, Poly(imino((1S)-1-carboxy-4-oxo-1,4-butanediyl)), alpha-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-omega-hydroxy-

ID: 552

InChIKey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 126941
synonyms found at PubChem are:
methotrexate, 59-05-2, Rheumatrex, Abitrexate, Amethopterin, Trexall, Mexate, Metatrexan, Hdmtx, Methylaminopterinum, Antifolan, Ledertrexate, Methylaminopterin, Methotrexatum, Methotrexat, Metotrexato, MTX, 4-Amino-10-methylfolic acid, L-Amethopterin, (S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid, Folex, N-Bismethylpteroylglutamic acid, Amethopterine, Methoxtrexate, Maxtrex, Rasuvo, A-Methopterin, Mexate-Aq, A-Methpterin, Emtexate, Amethopterin L-, Folex-Pfs, Methotrexat-Ebewe, Methotrexate, L-, Methotrexate Lpf, Metotressato [DCIT], Folex Pfs, Methotextrate, METHOTREXATE SODIUM, 133073-73-1, NSC 740, NSC-740, CL-14377, NCI-C04671, UNII-YL5FZ2Y5U1, [3H]methotrexate, Methotrexatum [INN-Latin], Metotrexato [INN-Spanish], (+)-4-Amino-10-methylfolic acid, [3H]-methotrexate, EMT 25,299, CCRIS 1109, 4-Aminomethylpteroylglutamic acid, HSDB 3123, TCMDC-125858, Abitrexate (Methotrexate), EINECS 200-413-8, R 9985, YL5FZ2Y5U1, CHEMBL34259, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid, AI3-25299, NSC740, X 133, 4-Amino-N(sup 10)-methylpteroylglutamic acid, CHEBI:44185, L-(+)-N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid, N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-(+)-glutamic acid, Antifolan hydrate, MTX hydrate, Kyselina 4-amino-N(sup 10)-methylpteroylglutamova [Czech], NCGC00025060-04, C20H22N8O5, CL 14377, 4-amino-N(10)-methylpteroylglutamic acid, DSSTox_CID_822, Mexate-Aq Preserved, N-(p-(((2,4-Diamino-6-pteridyl)methyl)methylamino)benzoyl)glutamic acid, N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamicacid, DSSTox_RID_75810, Kyselina N-(p-((2,4-diamino-6-pteridinylmethyl)methylamino)benzoyl)-L-glutamova [Czech], DSSTox_GSID_20822, Methylaminopterin hydrate, Fauldexato, Medsatrexate, Methoblastin, Metotressato, Brimexate, Emthexat, Emthexate, Lantarel, Lumexon, Metrotex, Novatrex, Otrexup, Tremetex, Trexeron, Trixilem, Metex, Texate, MLS001401431, Methotrexate Preservative Free, MFCD00150847, (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid, Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, L-, N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid, SMR000112001, 4-Amino-10-methylfolic acid hydrate, SR-01000075682, SMR000449324, METHOTREXATE SODIUM PRESERVATIVE FREE, Arbitrexate, FBOZXECLQNJBKD-UHFFFAOYSA-N, Methotrate, Metolate, Xatmep, Intradose-MTX, 1dhi, 1dhj, 2drc, 4ocx, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid, N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid, N-{4-[[(2,4-diaminopteridin-6-yl)methyl](methyl)amino]benzoyl}-L-glutamic acid, CAS-59-05-2, Kyselina N-(p-((2,4-diamino-6-pteridinylmethyl)methylamino)benzoyl)-L-glutamova, (2S)-2-[(4-([(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO)PHENYL)FORMAMIDO]PENTANEDIOIC ACID, MPI-2505, Prestwick_322, Methotrexate [USAN:INN:BAN:JAN], Otrexup (TN), Xatmep (TN), folic acid antagonist, An-PDN, L-METHOTREXATE, Methotrexate 100mg, Methylaminopterin; MTX, DL-Amethopterin hydrate, Intrathecal methotrexate, Methotrexate [USAN:USP:INN:BAN:JAN], Spectrum_001836, Tocris-1230, 4kn0, WR-19039, METHYLAMINOPTERINE, N-(4-{[(2,4-Diaminopteridin-1-Ium-6-Yl)methyl](Methyl)amino}benzoyl)-L-Glutamic Acid, Prestwick0_000135, Prestwick1_000135, Prestwick2_000135, Spectrum2_001077, Spectrum3_000497, Spectrum4_000616, Spectrum5_000958, Methotrexate - Abitrexate, D07ALU, D0D3DU, D0SV8E, L(+)-Amethopterin hydrate, NCIMech_000767, SCHEMBL3711, BIDD:PXR0175, L-(+)-AMETHOPTERIN, Lopac0_000020, KBioGR_001172, KBioSS_002341, KSC269O8T, Kyselina 4-amino-N(sup 10)-methylpteroylglutamova, MLS000049968, MLS002154208, DivK1c_000114, SPBio_001094, SPBio_002149, AC1L2R79, cid_126941, cid_165528, GTPL4674, GTPL4815, DTXSID4020822, SCHEMBL12421860, BDBM18050, BDBM66082, CTK1G9789, HMS500F16, KBio1_000114, KBio2_002338, KBio2_004906, KBio2_007474, KBio3_001493, Methotrexate (JP17/USP/INN), AOB5585, FBOZXECLQNJBKD-ZDUSSCGKSA-N, g301, MolPort-003-665-521, NINDS_000114, Bio1_000486, Bio1_000975, Bio1_001464, HMS1568K12, HMS2095K12, HMS2233O18, HMS3260C21, HMS3712K12, ACT03341, APC-2002, BCP13701, KS-00000L8X, MPI-5004, ZINC1529323, Tox21_110944, Tox21_300269, Tox21_500020, ANW-72813, CCG-35800, LS-249, s1210, 15475-56-6 (hydrochloride salt), AKOS016340329, Tox21_110944_1, 7413-34-5 (di-hydrochloride salt), AB02593, ACN-050905, CL14377, CS-1732, DB00563, KS-5093, LP00020, MCULE-6523054194, RTR-020497, IDI1_000114, SMP2_000020, (methyl)amino)benzamido)pentanedioic acid, NCGC00025060-01, NCGC00025060-02, NCGC00025060-03, NCGC00025060-05, NCGC00025060-06, NCGC00025060-07, NCGC00025060-08, NCGC00025060-09, NCGC00025060-10, NCGC00025060-11, NCGC00025060-12, NCGC00025060-13, NCGC00025060-15, NCGC00025060-16, NCGC00254216-01, NCGC00260705-01, AJ-26587, BC202627, BR-77824, HY-14519, SC-19293, 4-Amino-N10-methylpteroyl-L-glutamic acid, EU-0100020, FT-0082628, FT-0601523, Methotrexate 1.0 mg/ml in Dimethyl Sulfoxide, 1771-EP0930075A1, 1771-EP2269989A1, 1771-EP2269994A1, 1771-EP2270001A1, 1771-EP2270008A1, 1771-EP2270018A1, 1771-EP2270505A1, 1771-EP2272825A2, 1771-EP2272827A1, 1771-EP2272832A1, 1771-EP2275413A1, 1771-EP2275420A1, 1771-EP2277565A2, 1771-EP2277566A2, 1771-EP2277567A1, 1771-EP2277568A2, 1771-EP2277569A2, 1771-EP2277570A2, 1771-EP2277865A1, 1771-EP2277876A1, 1771-EP2280012A2, 1771-EP2281563A1, 1771-EP2281815A1, 1771-EP2287156A1, 1771-EP2289892A1, 1771-EP2289894A2, 1771-EP2292233A2, 1771-EP2292280A1, 1771-EP2292595A1, 1771-EP2292614A1, 1771-EP2292615A1, 1771-EP2292617A1, 1771-EP2295055A2, 1771-EP2295416A2, 1771-EP2295426A1, 1771-EP2295427A1, 1771-EP2298743A1, 1771-EP2298748A2, 1771-EP2298764A1, 1771-EP2298765A1, 1771-EP2298768A1, 1771-EP2298772A1, 1771-EP2298778A1, 1771-EP2298780A1, 1771-EP2301928A1, 1771-EP2301933A1, 1771-EP2305243A1, 1771-EP2305640A2, 1771-EP2305642A2, 1771-EP2305660A1, 1771-EP2305668A1, 1771-EP2305671A1, 1771-EP2305679A1, 1771-EP2305689A1, 1771-EP2308833A2, 1771-EP2308839A1, 1771-EP2308855A1, 1771-EP2308861A1, 1771-EP2311453A1, 1771-EP2311807A1, 1771-EP2311808A1, 1771-EP2311825A1, 1771-EP2311827A1, 1771-EP2311829A1, 1771-EP2311840A1, 1771-EP2311842A2, 1771-EP2311850A1, 1771-EP2314590A1, 1771-EP2316459A1, 1771-EP2316832A1, 1771-EP2316833A1, 1771-EP2316834A1, 1771-EP2371811A2, 1771-EP2374454A1, 5947-EP0930075A1, 5947-EP2269994A1, 5947-EP2289892A1, 73M731, A-2190, C01937, D00142, J10045, DL-4-Amino-N10-methylpteroylglutamic acid hydrate, SR-01000597411, W-60383, (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl), I06-2098, Q-201366, SR-01000075682-1, SR-01000075682-2, SR-01000075682-6, SR-01000597411-1, W-105347, 2,2'-(9,10-anthracenediylidene)-bis-propanedinitrile, BRD-K59456551-001-09-3, BRD-K59456551-001-11-9, I14-18123, WLN: T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVQ2VQ, Z1541638527, UNII-99ITO15X8S component FBOZXECLQNJBKD-ZDUSSCGKSA-N, Methotrexate, European Pharmacopoeia (EP) Reference Standard, Methotrexate, United States Pharmacopeia (USP) Reference Standard, Glutamic acid,4-diamino-6-pteridinyl)methyl] methylamino]benzoyl]-, L-(+)-, L-Glutamic acid,4-diamino-6-pteridinyl)methyl]- methylamino]benzoyl]-, L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-,hydrate(9ci), L-Glutamicacid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, Methotrexate for peak identification, European Pharmacopoeia (EP) Reference Standard, Methotrexate for system suitability, European Pharmacopoeia (EP) Reference Standard, Methotrexate, Pharmaceutical Secondary Standard; Certified Reference Material, N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYL)METHYLAMINO)BENZOYL)L-GLUTAMIC ACID, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl] methylamino]benzoyl]-L-glutamic acid, (2S)-2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid;hydrate, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]glutaric acid;hydrate, (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;hydrate, (2S)-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid;hydrate, (S)-2-(4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-METHYL-AMINO]-BENZOYLAMINO)-PENTANEDIOIC ACID, 1082707-84-3, 70359-39-6, L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, hydrate (9CI), Methotrexate, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, meets EP, USP testing specifications

ID: 553

InChIKey: FBSMERQALIEGJT-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6240
synonyms found at PubChem are:
Chlorpromazine hydrochloride, 69-09-0, Sonazine, Chlorpromazine Hcl, Chloractil, Klorpromex, Promacid, Hebanil, Propaphenin, Hibernal, Hybernal, Klorproman, Lomazine, Marazine, Neurazine, Norcozine, Plegomazin, Promachel, Promexin, Taroctyl, Tranzine, Promapar, Unitensen, Aminazinum, Hibanil, Megatil, Chlorpromazinium chloride, Aminazin monohydrochloride, Fenactil monohydrochloride, Chloropromazine monohydrochloride, Ampliactil monohydrochloride, Contomin hydrochloride, Megaphen hydrochloride, Chlorpromazine monohydrochloride, Largactil monohydrochloride, NCI-C05210, CHLOROPROMAZINE HYDROCHLORIDE, CPZ (VAN), Chlorpromazine, Hydrochloride, Chlorpromazine (hydrochloride), CCRIS 6221, UNII-9WP59609J6, EINECS 200-701-3, NSC 17479, [3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-dimethylamine hydrochloride, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine hydrochloride, AI3-28023, MLS000069401, CHEBI:3649, 10-(3-Dimethylaminopropyl)-2-chlorophenothiazine monohydrochloride, 9WP59609J6, SMR000058254, 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine monohydrochloride, 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, monohydrochloride, 2-Chloro-10-[3-dimethylamino-propyl] phenothiazine, 4560 Rp hydrochloride, AC1LCWF1, Phenothiazine hydrochloride, [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride, Chlorpromazine-d6 Hydrochloride, 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, 2-Chloro-10-[3′-(dimethylamino)propyl]phenothiazine, HCl, Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-, monohydrochloride, 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1), CPD000058254, NSC17479, CAS-69-09-0, SR-01000000012, CPZ, Chloropromazin hydrochloride, Largaktyl, [3-(2-chlorophenothiazin-10-yl)propyl]dimethylamine, chloride, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine;hydrochloride, Prestwick_58, Sonazine (TN), Chlorpromazine Hydrochloride Intensol, Chlorpromazine chloride, AC1Q3BDA, Chlorpromazine hydrochloride [USP:BAN:JAN], Opera_ID_1294, Chlorpromazine hydrochloride [USAN:BAN:JAN], C17H19ClN2S.HCl, DSSTox_CID_4827, AC1L1M3I, CHEMBL1713, DSSTox_RID_77545, DSSTox_GSID_24827, SCHEMBL41771, MLS001148603, MLS002222157, ARONIS23911, ChlorpromazineHydrochloride,98%, DTXSID7024827, CTK8B3386, HY-B0407A, FBSMERQALIEGJT-UHFFFAOYSA-N, MolPort-003-928-768, Chlorpromazine hydrochloride, 98%, HMS1568M09, Tox21_300517, Tox21_500249, ANW-42443, MFCD00012654, NSC-17479, NSC226514, s2456, SBB057793, AKOS005111082, CCG-220064, CCG-221553, CS-2507, LP00249, LS-1585, MCULE-8792081568, NC00552, NSC-226514, KS-00000V46, Chlorpromazine hydrochloride (JP17/USP), NCGC00024409-09, NCGC00093711-01, NCGC00093711-02, NCGC00180973-01, NCGC00254272-01, NCGC00260934-01, AC-10573, AN-23781, H818, SAM002548952, SAM002564196, SC-18311, AB0013284, AB1009377, TR-031509, Chlorpromazine hydrochloride, >=98% (TLC), EU-0100249, FT-0623715, ST50331291, C 8138, C07952, D00789, MLS-0090820.0001, WLN: T C666 BN ISJ B3N1&1 EG &GH, 012C654, Q-200842, SR-01000000012-2, SR-01000000012-9, Z1259155914, 2-chloro-10-(3-dimethylaminopropyl) phenothiazine hydrochloride, 2-chloro-10-(3-dimethylaminopropyl)-phenothiazine hydrochloride, Chlorpromazine hydrochloride, meets USP testing specifications, Chlorpromazine hydrochloride, VETRANAL(TM), analytical standard, 10-[3-(dimethylamino)propyl]-2-chlorophenothiazine hydrochloride, 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine monohydrochloride, 2-Chloro-10-[3-(dimethylamino)-1-propyl]phenothiazine Hydrochloride, Chlorpromazine Hydrochloride 1.0 mg/ml in Methanol (as free base), 10H-phenothiazine-10-propanamine hydrochloride, 2-chloro-N,N-dimethyl-, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine hydrochloride, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine hydrochloride, Chlorpromazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride; CPZ; Largactil, Chlorpromazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, MLS000595399, SMR000149922, AC1LAWRW, Opera_ID_1263, HMS2234H07, HMS3370H01, [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-ammonium, 3-(2-chlorophenothiazin-10-yl)propyl-dimethylazanium chloride, AKOS015895975, I06-1260, 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine monohydrochloride, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine; hydron; chloride

ID: 554

InChIKey: FBUBVLUPUDBFME-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=C(C=C1OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 66654
synonyms found at PubChem are:
Xanthoxylin, 90-24-4, Xanthoxyline, 2'-Hydroxy-4',6'-dimethoxyacetophenone, 2-Hydroxy-4,6-dimethoxyacetophenone, Brevifolin, 1-(2-Hydroxy-4,6-dimethoxyphenyl)ethanone, Brevifolin (Zanthoxylum), Phloracetophenone dimethyl ether, Brevifolin (VAN), 1-(2-Hydroxy-4,6-dimethoxyphenyl)ethan-1-one, 2,4-Di-O-methylphloroacetophenone, 4,6-Dimethoxy-2-hydroxyacetophenone, Phloroacetophenone 2,4-dimethyl ether, UNII-Z8RSY5TZPA, Acetophenone der., Ethanone, 1-(2-hydroxy-4,6-dimethoxyphenyl)-, 1-Acetyl-2-hydroxy-4,6-dimethoxybenzene, Z8RSY5TZPA, NSC 17392, 4',6'-dimethoxy-2'-hydroxyacetophenone, CHEBI:10070, FBUBVLUPUDBFME-UHFFFAOYSA-N, 2-Hydroxyl-4,6-dimethoxy-acetophenone, 1-(2-hydroxy-4,6-dimethoxy-phenyl)ethanone, Acetophenone, 2'-hydroxy-4',6'-dimethoxy-, AQ-358/42007313, Acetophenone, 2'-hydroxy-4',6'-dimethoxy- (8CI), brevifolin(van), 6-Methoxypaeonol, EINECS 201-978-3, Spectrum_000577, SpecPlus_000713, AI3-26010, Spectrum2_000463, Spectrum3_000181, Spectrum4_001499, Spectrum5_000237, ACMC-209r5b, AC1L25UT, AC1Q5D4Z, Acetophenone,6'-dimethoxy-, SCHEMBL44708, BSPBio_001701, KBioGR_002137, KBioSS_001057, SPECTRUM200441, MLS002207182, DivK1c_006809, SPBio_000566, 2-Acetyl-3,5-dimethoxyphenol, CHEMBL450288, CTK3J0177, KBio1_001753, KBio2_001057, KBio2_003625, KBio2_006193, KBio3_001201, DTXSID10237981, MolPort-001-762-282, ZINC157077, KS-000012GK, NSC17392, ZX-AT021196, ANW-39453, CCG-38702, NSC-17392, SBB071509, 2-Hydroxy-4, 6-dimethoxyacetophenone, 4, 6-Dimethoxy-2-hydroxyacetophenone, AKOS015856339, FCH1116672, MCULE-4292389127, OR22374, RTR-030636, SDCCGMLS-0066937.P001, TRA0050729, 2'-hyroxy-4',6'-dimethoxyacetophenone, NCGC00095824-01, NCGC00095824-02, 4CN-0948, AJ-14872, AK135500, AS-40799, SC-69796, SMR001306755, ST098711, ZB006545, 2'-Hydroxy-4',6'-dimethoxy-Acetophenone, (2-hydroxy-4,6-dimethoxy-phenyl)-ethanone, AB1004782, AX8000172, KB-146755, TR-030636, 1-(2-hydroxy-4,6-dimethoxyphenyl)-ethanone, D2683, FT-0612544, ST24037116, 1-(2-Hydroxy-4,6-dimethoxyphenyl)ethanone #, 2'-Hydroxy-4',6'-dimethoxyacetophenone, 97%, A-8021, C10726, Ethanone,1-(2-hydroxy-4,6-dimethoxyphenyl)-, SR-05000002434, 2''-HYDROXY-4'',6''-DIMETHOXYACETOPHENONE, Brevifolin; 4',6'-Dimethoxy-2'-hydroxyacetophenone, SR-05000002434-1, BRD-K12260308-001-02-6, BRD-K12260308-001-04-2, I14-19971

ID: 555

InChIKey: FBWNMEQMRUMQSO-UHFFFAOYSA-N
SMILES: CCCCCCCCCC1=CC=C(C=C1)OCCOCCOCCOCCOCCOCCOCCOCCOCCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 72385
synonyms found at PubChem are:
Nonoxynol-9, Nonoxynol 9, Delfen, ToDay, Nonoxynol, n=9, 14409-72-4, PEG-9 Nonyl phenyl ether, Tergitol NP9, Nonaethylene glycol nonylphenyl ether, Nonylphenol octa(oxyethylene) ethanol, Tergitol NP-9, Nonaethylene glycol mono(nonylphenyl) ether, 26-(Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol, 26571-11-9, CHEBI:53775, 26-(4-nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol, Polyethylene Glycol Mono-4-nonylphenyl Ether, N-9, 2-[2-[2-[2-[2-[2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, Staycept, Gynoll, HSDB 8094, C-Film, Tergitol TP-9, EINECS 247-816-5, K-Y plus nonoxynol-9, NONOXINOL-9, Spectrum2_001247, Spectrum3_001946, AC1L2HZ4, AC1Q56ZY, CHEMBL1410, SCHEMBL36844, BSPBio_003546, SPECTRUM1505292, SPBio_001154, Dowfax 9N9, Neutronyx 611, CO-630SP, CTK8B3251, KBio3_002833, DTXSID00858720, HMS2093O22, Pharmakon1600-01505292, ZINC8214629, 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(nonylphenoxy)-, ANW-42093, BDBM50442874, CCG-39124, NSC758941, AKOS015910808, DB06804, NSC-758941, NCGC00095907-02, NCGC00095907-03, N 9, SBI-0206761.P001, TR-011783, AB01563056_01, SR-05000001885, J-016227, Q-201490, SR-05000001885-1, BRD-K88625236-001-01-8, I14-40150, 1-(4-nonylphenyl)-1,4,7,10,13,16,19,22,25-nonaoxaheptacosan-27-ol, 41257-07-2, N9, VCF

ID: 556

InChIKey: FBZONXHGGPHHIY-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=C1)O)NC(=CC2=O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5699
synonyms found at PubChem are:
xanthurenic acid, 59-00-7, 4,8-Dihydroxyquinoline-2-carboxylic acid, Xanthuric acid, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid, 4,8-Dihydroxyquinaldinic acid, Xanthurenate, 2-Quinolinecarboxylic acid, 4,8-dihydroxy-, UNII-58LAB1BG8J, NSC 401570, 8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid, C10H7NO4, CCRIS 4429, 4,8-Dihydroxy-2-quinolinecarboxylic acid, EINECS 200-410-1, NSC401570, BRN 0185954, 58LAB1BG8J, QUINALDIC ACID, 4,8-DIHYDROXY-, CHEMBL312535, CHEBI:10072, FBZONXHGGPHHIY-UHFFFAOYSA-N, X-1500, 4,8-Dihydroxyquinoline-2-carboxylate, Oxoxanthurenate, Xanthurate, gametocyte activating factor (GAF), 8-Hydroxykynurenate, 4-oxoxanthurenic acid, Spectrum_000253, 4,8-Dihydroxyquinaldate, Xanthurenic acid, 96%, AC1L1KXT, Spectrum2_000158, Spectrum3_000143, Spectrum4_000117, Spectrum5_001562, 4,8-dihydroxy-Quinaldate, 4,8-Dihydroxyquinaldinate, Quinaldic acid,8-dihydroxy-, Oprea1_107134, BSPBio_001846, KBioGR_000474, KBioSS_000733, 4,8-dihydroxy-Quinaldic acid, BIDD:GT0640, DivK1c_000262, SCHEMBL379760, SPECTRUM1500754, SPBio_000296, CTK1H0426, HMS500N04, KBio1_000262, KBio2_000733, KBio2_003301, KBio2_005869, KBio3_001046, DTXSID90207728, MolPort-001-792-867, MolPort-019-999-046, NINDS_000262, HMS1921G08, WLN: T66 BNJ CVQ EQ JQ, 4,8-DIHYDROXYGUINALDIC ACID, AC1Q7330, ZINC8738372, 4,8-dihydroxyquinoline-2-carboxylic, 5527AH, ANW-43693, BDBM50113313, CCG-38363, KM0268, SBB003498, 4,8-Dihydroxy-2-quinolinecarboxylate, AKOS003237896, AKOS015894330, 4,8-dihydroxyquinolinium-2-carboxylate, ACN-049214, API0004623, CS-W015382, HY-W014666, MCULE-1038310399, NSC-401570, RTR-020475, SDCCGMLS-0066616.P001, TRA0094822, 2-Quinolinecarboxylic acid,8-dihydroxy-, IDI1_000262, NCGC00094846-01, NCGC00094846-02, NCGC00094846-03, NCGC00094846-04, NCGC00094846-05, AJ-73368, AJ-73369, AN-41776, BP-10912, CC-17435, KB-62283, 2-Quinolinecarboxylicacid, 4,8-dihydroxy-, AX8000398, DB-053303, LS-139872, TR-020475, AM20061355, B7593, FT-0631263, ST24042681, ST45025626, Quinoline-2-carboxylic acid, 4,8-dihydroxy-, C02470, 4,8-Dihydroxy-quinoline-2-carboxylic acid anion, 059D007, A832107, C-10125, SR-05000002445, 2-Quinolinecarboxylic acid, 4,8-dihydroxy- (9CI), CU-01000012491-3, I04-9457, SR-05000002445-1, BRD-K07327532-001-03-6, 4,8-Dihydroxy-quinoline-2-carboxylic acid(Xanthurenate), 8-hydroxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, 8-oxidanyl-4-oxidanylidene-1H-quinoline-2-carboxylic acid, B5FF212D-76CB-4875-8A36-C67D8E69489C, 4KL

ID: 557

InChIKey: FCEVNJIUIMLVML-QPSVUOIXSA-N
SMILES: C/C=C\1/CC(=C)[C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281750
synonyms found at PubChem are:
SENECIPHYLLINE, 480-81-9, Seneciphyllin, Jacodine, NSC30622, UNII-0ZYZ9L5454, Seniciphylline, MLS000737616, CHEBI:9108, 0ZYZ9L5454, 13,19-Didehydro-12-hydroxysenecionan-11,16-dione, NSC 30622, CCRIS 4336, HSDB 5188, Seneciphylline, analytical standard, (1R,7R,17R)-4-ethylidene-7-hydroxy-7-methyl-6-methylene-2,9-dioxa-14-azatricyc lo[9.5.1.0<14,17>]heptadec-11-ene-3,8-dione, SMR000393787, NCI-C61165, Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-, trans-15-Ethylidene-12beta-hydroxy-12alpha-methyl-13-methylenesenec-1-enine, Prestwick_446, Prestwick2_000599, Prestwick3_000599, BSPBio_000478, MLS002222214, SCHEMBL177867, BPBio1_000526, CHEMBL523911, DTXSID8026016, CHEBI:92677, MolPort-004-955-368, HMS1569H20, HMS2096H20, HMS2763J21, (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-, (3Z,6R,14aR,14bR)-, NSC-30622, ZINC95627757, AKOS024282719, NCGC00017384-04, NCGC00142562-03, 4CN-1935, ST057705, C10391, Senecionan-11, 13,19-didehydro-12-hydroxy-, (Z)-ethylidene-hydroxy-methyl-methylene-[?]dione, BRD-K38449220-001-03-8, Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy- (9CI), 2H-Pyran-2-carboxylicacid,5-ethyltetrahydro-2,3-dimethyl-6-oxo-(9ci), (3Z,6R,14aR,14bR)-3-ethylidene-6-hydroxy-6-methyl-5-methylene-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, (6R,9a1R,14aR,Z)-3-ethylidene-6-hydroxy-6-methyl-5-methylene-3,4,5,6,9,9a1,11,13,14,14a-decahydro-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,(3Z,6R,14aR,14bR)-, Pyrrolizine-2, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene(1,6)dioxacyclododecino[2,3,4-gh]-

ID: 558

InChIKey: FCFZKAVCDNTYID-UHFFFAOYSA-M
SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2733504
synonyms found at PubChem are:
Diphenyleneiodonium chloride, 4673-26-1, Dibenziodolium chloride, UNII-7M9D81YZ2N, DPI, 7M9D81YZ2N, CHEBI:77967, CHEMBL397686, SR-01000075494, Dibenziodolium, chloride, D0N0GJ, AC1MBZ20, C12H8I.Cl, dibenzo[b,d]iodolium chloride, SCHEMBL159318, GTPL7802, CTK8F9249, DTXSID00196932, MolPort-003-983-758, MolPort-023-275-892, HMS3261I15, HMS3266G10, 2,2'-biphenylyleneiodonium chloride, BCP08692, Tox21_500367, 1726AH, Diphenyleneiodonium chloride, >=98%, MFCD00214165, AKOS015903219, CCG-221671, LP00367, NCGC00093801-01, NCGC00093801-02, NCGC00261052-01, HY-100965, CS-0020645, EU-0100367, [1,1'-Biphenyl]-2,2'-diyiodonium chloride, [1,1'-Biphenyl]-2,2'-diyliodonium chloride, KS-00001873, D 2926, SR-01000075494-1, SR-01000075494-3, I14-18990, I14-41043, 8$l^{3}-iodatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-8-ylium chloride, 8|E3-iodatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaen-8-ylium chloride, 8lambda(3)-iodatricyclo[7.4.0.0(2),]trideca-1(13),2,4,6,9,11-hexaen-8-ylium chloride

ID: 559

InChIKey: FCPVYOBCFFNJFS-LQDWTQKMSA-M
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6250
synonyms found at PubChem are:
Penicillin G sodium, Penicillin G sodium salt, 69-57-8, Benzylpenicillin sodium, Crystapen, American penicillin, Pencillin G sodium, Sodium penicillin G, BENZYLPENICILLIN SODIUM SALT, Sodium penicillin, Sodium benzylpenicillinate, Sodium penicillin II, Mycofarm, Novocillin, Penilaryn, Veticillin, Sodium benzylpenicillin, Kesso-Pen, Pen-A-Brasive, Sodium benzylpenicillin G, Monosodium benzylpenicillin, Benzylpenicillinic acid sodium salt, Penicillin G, sodium, Sugracillin sodium salt, Penicillin G Sodium, Crystalline, Sodium benzylpenicyllinate, UNII-YS5LY7JF4N, Penicillin-G, monosodium salt, Sodium 6-(phenylacetamido)penicillanate, EINECS 200-710-2, OK 431, YS5LY7JF4N, Penicillin, NSC 402815, Penicillin G sodium [USP], CHEBI:51765, Penicillin G sodium (USP), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-, monosodium salt, Monosodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 61-33-6 (Parent), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, monosodium salt, Sodium (2S-(2alpha,5alpha,6beta))-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, PenicillinGsodiumsalt, 61-33-6 (FREE ACID), Penicillin G Sodium [USAN], CHEMBL1126, D0K5OT, Penicillin G sodium (TN), sodium benzylpenicillin(1-), C16H17N2NaO4S, SCHEMBL34218, C16H17N2O4S.Na, DTXSID6040581, KS-00000WAN, BIP0142, BENZYL PENICILLIN POTASSIUM, FCPVYOBCFFNJFS-LQDWTQKMSA-M, MolPort-003-926-371, ZX-AFC000647, Benzylpenicillin sodium salt AAENI, HMS1571G18, HMS2098G18, HMS3715G18, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-(2S,5R,6R)-, monosodium salt, HY-B1463, MFCD00069666, s4160, AKOS015961217, CCG-221078, CS-7971, LS-1587, CAS-69-57-8, NCGC00017015-01, Penicillin G sodium salt, ~1650 U/mg, AC-13436, AN-23784, E706, K162, SC-16403, Penicillin G sodium salt, 96.0-102.0%, FT-0603271, P1770, D05408, P-1200, F0001-2583, Pencillin G sodium salt, Antibiotic for Culture Media Use Only, sodium 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate, Benzylpenicillin sodium, European Pharmacopoeia (EP) Reference Standard, Penicillin G sodium salt, powder, BioReagent, suitable for cell culture, Penicillin G sodium, United States Pharmacopeia (USP) Reference Standard, PENICILLIN G, SODIUM SALT (ALSO SEE: 1538-09-6 BENZATHINE PEN. G), 1406-09-3, 8049-60-3, sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylate

ID: 560

InChIKey: FDAYLTPAFBGXAB-UHFFFAOYSA-N
SMILES: C(CCl)N(CCCl)CCCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5561
synonyms found at PubChem are:
trichlormethine, TRIS(2-CHLOROETHYL)AMINE, 555-77-1, Sinalost base, Trimitan base, Tris-(2-chloroethyl)-amine, Trimustine, 2-Chloro-N,N-bis(2-chloroethyl)ethanamine, Agent HN3, SK 100, TL 145, TS 160, 2,2',2''-Trichlorotriethylamine, Tri-(2-chloroethyl)amine, Nitrogen mustard (HN-3), UNII-66WBM7N0NM, Tris(beta-chloroethyl)amine, C6H12Cl3N, Triclormetina [INN-Spanish], Trichlormethinum [INN-Latin], A 8729, Ethanamine, 2-chloro-N,N-bis(2-chloroethyl)-, trichlorotriethylamine, Triethylamine, 2,2',2''-trichloro-, CCRIS 7606, HN 3, HN-3, HSDB 6395, Tri-2-chloroethylamine, NSC 30211, BRN 1739647, 66WBM7N0NM, Tris(.beta.-chloroethyl)amine, AI3-16198, FDAYLTPAFBGXAB-UHFFFAOYSA-N, DSSTox_CID_28670, DSSTox_RID_82940, DSSTox_GSID_48744, Triclormetina, Trichlormethinum, CAS-555-77-1, TS-160, Trichlormethine [INN], NSC-260424, NCGC00095905-01, Trichlormethine [INN:BAN], trichloromethine, Triethylamine, 2,2',2"-trichloro-, Sinalost (Salt/Mix), Trimitan (Salt/Mix), Trillekamin (Salt/Mix), HN3 (nitrogen mustard), AC1L1KME, R 47 (Salt/Mix), Spectrum2_000780, Spectrum3_001231, Spectrum4_000113, Spectrum5_000965, tris-(2-chloroethyl)amine, Tris-N-lost (Salt/Mix), Tris(2-chloroethyl)-amine, SCHEMBL8224, Tris-.beta.-Chloroethylamine, WLN: G2N2G2G, BSPBio_002702, KBioGR_000466, tris-(2-chloro-ethyl)-amine, 2,2''-Trichlorotriethylamine, DivK1c_000728, SPBio_000860, 817-09-4 (hydrochloride), CHEMBL443613, 2,2',2''-trichloroethylamine, 6138-32-5 (monopicrate), DTXSID7048744, 2,2',2'-Trichlorotriethylamine, CTK5A3818, HMS502E10, KBio1_000728, KBio3_002202, NINDS_000728, Ethanamine,N-bis(2-chloroethyl)-, Triethylamine,2',2''-trichloro-, 2, 2',2''-trichlorotriethylamine, HY-B1249, NSC30211, Tox21_113198, 4698AJ, ZINC38139367, AKOS022145597, Tox21_113198_1, CS-4959, FCH1321619, NE63177, IDI1_000728, NCGC00178521-01, NCGC00178521-03, SBI-0051749.P002, LS-157415, FT-0706146, 2-chloranyl-N,N-bis(2-chloroethyl)ethanamine, 2-Chloro-N,N-bis(2-chloroethyl)ethanamine #, Ethanamine,2-chloro-N,N-bis(2-chloroethyl)-, AB00053635_02, A830707, C-50085

ID: 561

InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5333
synonyms found at PubChem are:
sulfanilamide, 4-Aminobenzenesulfonamide, 63-74-1, Sulphanilamide, Sulfamine, Sulphonamide, p-Aminobenzenesulfonamide, Sulfonylamide, Sulfonamide, p-Aminobenzenesulfamide, Bacteramid, Streptasol, p-Sulfamoylaniline, Prontosil Album, Sulfonamide P, Estreptocida, Exoseptoplix, Streptoclase, p-Sulfamidoaniline, Streptocide, Sulfamidyl, Sulfanalone, Sulfanidyl, Sulfanil, Sulfocidine, Sulfana, Sulfanilimidic acid, p-Anilinesulfonamide, p-Aminophenylsulfonamide, Ambeside, Antistrept, Astreptine, Astrocid, Bactesid, Collomide, Colsulanyde, Copticide, Deseptyl, Ergaseptine, Erysipan, Gombardol, Lysococcine, Neococcyl, Orgaseptine, Prontalbin, Prontylin, Proseptal, Proseptine, Proseptol, Pysococcine, Septanilam, Septinal, Septolix, Septoplex, Septoplix, Strepamide, Strepsan, Streptagol, Streptamid, Streptamin, Streptocid, Streptocom, Strepton, Streptopan, Streptosil, Streptozol, Streptozone, Streptrocide, Sulfocidin, Therapol, 4-Sulfamoylaniline, Albexan, Albosal, Dipron, Gerison, Infepan, Sanamid, Stramid, Tolder, Benzenesulfonamide, 4-amino-, Lusil, 4-Aminobenzene-1-Sulfonamide, Prontosil White, Pronzin Album, Septamide Album, Stopton Album, Streptocid album, Prontosil I, Rubiazol A, White streptocide, PABS, Streptocide White, p-Aminobenzenesulfonylamide, 4-Aminophenylsulfonamide, Fourneau 1162, Streptocidum, Sulfanilamide Vaginal Cream, Aniline-p-sulfonic amide, Sulfanilamida, Sulfanilamidum, Benzenesulfonamide, p-amino-, 4-Amino-benzenesulfonamide, Streptocide (VAN), Solfanilamide [DCIT], Caswell No. 809A, p-Aminobenzensulfonamide, HSDB 223, 1162 F, 4-azanylbenzenesulfonamide, A-349, Sulfanilamidum [INN-Latin], Sulfanilamida [INN-Spanish], C6H8N2O2S, CCRIS 764, F 1162, UNII-21240MF57M, CHEBI:45373, NSC 7618, CHEMBL21, EINECS 200-563-4, p-amino benzene sulfonamide, para-aminobenzenesulfonamide, EPA Pesticide Chemical Code 077902, BRN 0511852, AI3-00952, NSC7618, FDDDEECHVMSUSB-UHFFFAOYSA-N, 4-aminobenzene sulfonic acid amide, 21240MF57M, AVC, CAS-63-74-1, NCGC00016285-02, NCGC00016285-05, Sulfanilamide, >=99%, DSSTox_CID_3622, 3-ACTOXYMERCURI-4-AMINOBENZENESULFONAMIDE, DSSTox_RID_77115, DSSTox_GSID_23622, 1337-39-9, SMR000059035, SR-01000763435, sulfanilamine, Sulfanimide, Sulfanilamide [INN:DCF:NF], sulphanilic amide, 4-sulphanilamide, Sulfanimide,(S), Prestwick_36, 4-sulfamoyl-aniline, sulfanilamide reagent, sulfanilamide-reagent, 4-sulphamoyl aniline, Spectrum_000489, 4-aminobenzensulfonamide, WLN: ZSWR DZ, 4-(Aminosulfonyl)aniline, 4-aminobenzenesulphonamide, p-aminobenzene sulfonamide, Prestwick0_000729, Prestwick1_000729, Prestwick2_000729, Prestwick3_000729, Spectrum2_000846, Spectrum3_001406, Spectrum4_000398, Spectrum5_001081, 4-aminobenzene sulfonamide, 4-aminobenzene-sulfonamide, ACMC-1AYS4, p-aminosulfonyl phenylamine, SCHEMBL740, 4-amino-benzenesulphonamide, D0T8BA, Epitope ID:122232, AC1L1K4E, Oprea1_273157, p-aminobenzene sulfonyl amide, BSPBio_000658, BSPBio_003052, KBioGR_000955, KBioSS_000969, 4-14-00-02658 (Beilstein Handbook Reference), KSC490E8T, MLS001074682, MLS002152940, BIDD:GT0170, DivK1c_000528, SPECTRUM1500646, SPBio_000831, SPBio_002597, Sulfanilamide, 98% 100g, AC1Q51Y6, aromatic sulfonamide compound 5, BPBio1_000724, halogenosulfanilamide deriv. 5a, ZINC2101, (4-(Aminosulfonyl)phenyl)amine, DTXSID4023622, SCHEMBL11880061, 6101-31-1 (hydrochloride), BDBM10857, CTK3J0289, HMS501K10, KBio1_000528, KBio2_000969, KBio2_003537, KBio2_006105, KBio3_002272, Sulfanilamide, p.a., 99.0%, MolPort-000-871-476, NINDS_000528, HMS1570A20, HMS1921O07, HMS2092E20, HMS2097A20, HMS2233B19, HMS3370J16, HMS3655K19, HMS3714A20, Pharmakon1600-01500646, EBD35543, HY-B0242, KS-00000V0E, NSC-7618, Tox21_110351, Tox21_201331, Tox21_303336, ANW-43069, BBL005257, c1264, CCG-40302, LS-274, MFCD00007939, NSC757404, s1685, SBB008928, STK298902, 10103-15-8 (hydrochloride salt), AKOS000119305, Tox21_110351_1, CS-2221, DB00259, MCULE-8746683155, NSC-757404, RP23455, RTR-021919, IDI1_000528, NCGC00016285-01, NCGC00016285-03, NCGC00016285-04, NCGC00016285-06, NCGC00016285-08, NCGC00091144-01, NCGC00091144-02, NCGC00091144-03, NCGC00257174-01, NCGC00258883-01, AJ-08134, AN-23733, AS-13239, BP-12552, CJ-00080, H701, KB-36489, SC-16246, ST079295, Sulfanilamide (4-Aminobenzenesulfonamide), ZB000483, SBI-0051575.P002, 4-Aminobenzenesulphonamide (Sulphanilamide), AB1002011, KB-303071, ST2411104, TR-021919, AB00052138, FT-0657032, S0119, S0381, S0833, Sulfanilamide, JIS special grade, >=99.7%, Sulfanilamide, Vetec(TM) reagent grade, 97%, C07458, D08543, M-3994, 36799-EP2272517A1, 36799-EP2272834A1, 36799-EP2289871A1, 36799-EP2301923A1, 36799-EP2301929A1, 36799-EP2301935A1, 36799-EP2305250A1, 36799-EP2305640A2, 36799-EP2305674A1, 36799-EP2305808A1, 36799-EP2311796A1, 36799-EP2311797A1, 36799-EP2311798A1, 36799-EP2311799A1, 36799-EP2311801A1, 91143-EP2295053A1, 91143-EP2305219A1, AB00052138-10, AB00052138_11, AB00052138_12, A834498, AC-907/25014139, Sulfanilamide, VETRANAL(TM), analytical standard, I06-0505, SR-01000763435-2, SR-01000763435-3, SR-01000763435-4, F2190-0451, BENZENESULFONIC ACID,4-AMINO,AMIDE SULFANILAMIDE, Sulfanilamide, European Pharmacopoeia (EP) Reference Standard, Sulfanilamide, puriss. p.a., >=99% (calc. to the dried substance), Sulfanilamide, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10, Sulfanilamide Melting Point Standard, United States Pharmacopeia (USP) Reference Standard, 102489-34-9, 12765-80-9, 1337-36-6, 24706-25-0, Sulfanilamide melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 562

InChIKey: FDEACFAXFCKCHZ-MOROJQBDSA-N
SMILES: CCCCC#CC1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)C(=O)NCC)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 164437
synonyms found at PubChem are:
HE-NECA, 2-Hexynyl-NECA, Heneca, CHEMBL410873, 2-Hexynyl-5'-N-ethylcarboxamidoadenosine, 141018-30-6, (2S,3S,4R,5R)-5-(6-Amino-2-hex-1-ynyl-purin-9-yl)-N-ethyl-3,4-dihydroxy-oxolane-2-carboxamide, (2S,3S,4R,5R)-5-(6-amino-2-hex-1-ynylpurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide, 2-Hexynyladenosine-5'-N-ethylcarboxamide, AC1Q5OOO, AC1L4US1, Lopac0_000635, GTPL373, (2s,3s,4r,5r)-5-[6-amino-2-(hex-1-yn-1-yl)-9h-purin-9-yl]-n-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide(non-preferred name), SCHEMBL8102867, ZINC3779696, BDBM50453224, PDSP1_000292, PDSP1_000974, PDSP1_001061, PDSP2_000291, PDSP2_000958, PDSP2_001045, 2-Hexynyl-5'-ethylcarboxamidoadenosine, CCG-204723, 2-Hexynyl-5-N-ethylcarboxamidoadenosine, HE-NECA, solid, >=98% (HPLC), NCGC00094002-01, NCGC00094002-02, EU-0100635, H 8034, SR-01000075918, SR-01000075918-1, 2-Hexynyl-5 inverted exclamation marka-ethylcarboxamidoadenosine, 2-(1-Hexyn-1-yl)adenosine-5 inverted exclamation marka-N-ethyluronamide, beta-D-Ribosuranuronamide, 1-(6-amino-2-(1-hexynyl)-9H-purin-9-yl)-1-deoxy-N-ethyl-, (2S,3S,4R,5R)-5-(6-amino-2-hex-1-ynyl-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide

ID: 563

InChIKey: FDGHZUQYDACRTA-UHFFFAOYSA-N
SMILES: CCOC(=O)CCCCCCCCCCCCC1CCC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2700
synonyms found at PubChem are:
Chaulmoogric acid, ethyl ester, Chaulmoogric acid ethyl ester, NSC38010, Ethy6l chaulmoograte, 2-Cyclopentene-1-tridecanoic acid, ethyl ester, EINECS 210-786-9, Ethyl 2-cyclopentene-1-tridecanoate, NSC 38010, 2-Cyclopentene-1-tridecanoic acid, ethyl ester, (S)-, Ethyl 13-(cyclopent-2-enyl)tridecanoate, ETHYL CHAULMOOGRATE, 623-32-5, Spectrum_001411, Spectrum2_000511, Spectrum3_001357, Spectrum4_000118, Spectrum5_000724, ethyl 13-(cyclopent-2-en-1-yl)tridecanoate, AC1L1E9N, BSPBio_003173, KBioGR_000476, KBioSS_001891, SPECTRUM310017, DivK1c_000627, SPBio_000461, CHEMBL1329881, CTK5B4913, HMS501P09, KBio1_000627, KBio2_001891, KBio2_004459, KBio2_007027, KBio3_002393, NINDS_000627, AC1Q6578, CCG-39563, NSC-38010, IDI1_000627, NCGC00095864-01, NCGC00095864-02, LS-58339, ethyl 13-cyclopent-2-en-1-yltridecanoate, 2-Cyclopentene-1-tridecanoicacid, ethyl ester, (1S)-

ID: 564

InChIKey: FDGQSTZJBFJUBT-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1)C(=O)N=CN2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 790
synonyms found at PubChem are:
hypoxanthine, 68-94-0, 6-Hydroxypurine, 9H-Purin-6-ol, 6-Oxopurine, Sarkin, Sarcine, Sarkine, Purin-6(1H)-one, Purin-6-ol, Hypoxanthine enol, 6(1H)-Purinone, 7H-Purin-6-ol, 9H-Purin-6(1H)-one, 3H-Purin-6-ol, Purin-6(3H)-one, 6-Hydroxy-1H-purine, Purine-6-ol, 1,7-Dihydro-6H-purin-6-one, 6H-Purin-6-one, 1,7-dihydro-, 1H-Purin-6(9H)-one, 9H-Purin-6-ol (VAN), 1,9-dihydro-6H-purin-6-one, 3,7-dihydropurin-6-one, 6H-Purin-6-one, 1,9-dihydro-, NSC 14665, 1H-Purin-6-ol (9CI), 3H-Purin-6-ol (9CI), UNII-2TN51YD919, 6,7-dihydro-3H-purin-6-one, 146469-94-5, 1,7-Dihydro-6H-purine-6-one, CHEBI:17368, AI3-52242, EINECS 200-697-3, 1,9-dihydropurin-6-one, HX, CHEMBL1427, 9H-Purin-6-ol (9CI), Hypoxanthine (VAN) (8CI), FDGQSTZJBFJUBT-UHFFFAOYSA-N, 2TN51YD919, 146469-95-6, 51953-04-9, 95121-06-5, NCGC00095622-01, DSSTox_CID_25983, DSSTox_RID_81271, DSSTox_GSID_45983, 146445-70-7, AG-670/31547063, Hypoxanthine-13C2,15N, CAS-68-94-0, 51953-23-2, purin-6(1H)-on, 3h-hypoxanthine, 6-hydroxypurin, 1vfn, 3nrz, InChI=1/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10, Hypoxanthine,(S), 1h-purin-6-ol, Hypoxanthine (VAN), NSC 129419, PubChem9283, 4-Hydroxy-1H-purine, Spectrum_001417, 1a9q, 7H-Purin-6-ol #, SpecPlus_000461, AC1Q6GPF, Spectrum2_001907, Spectrum3_001352, Spectrum4_001742, Spectrum5_000564, 3H-purin-6(7H)-one, ACMC-1AY8Z, ACMC-209o5e, bmse000094, D03HVE, Epitope ID:167471, AC1Q2AP6, 1,9-Dihydro-purin-6-one, Hypoxanthine, >=99.0%, ACMC-1C9T0, SCHEMBL25381, 7H-Purin-6-ol (9CI), BSPBio_003163, C5H3N4O, KBioGR_002184, KBioSS_001897, SPECTRUM310023, KSC353S0F, DivK1c_006557, SPBio_001874, AC1L1A12, GTPL4555, SCHEMBL1867923, DTXSID8045983, SCHEMBL17276814, BDBM82018, CTK0H0419, CTK0H0424, CTK1E4768, CTK1G8777, CTK2F3902, CTK3I5985, FDGQSTZJBFJUBT-UHFFFAOYSA-, KBio1_001501, KBio2_001897, KBio2_004465, KBio2_007033, KBio3_002383, CAS_790, NSC_790, MolPort-000-510-424, MolPort-000-799-859, MolPort-001-783-695, MolPort-002-640-011, MolPort-003-941-579, BCP22929, HY-N0091, NSC14665, Tox21_111511, ANW-35568, CCG-38478, CH0066, EBD130553, MFCD00005725, NSC-14665, PDSP1_000299, PDSP2_000297, s2424, SBB004203, STK804424, ZINC18153302, AKOS000267572, AKOS005221762, AKOS009159101, AKOS015888571, AKOS022168213, AKOS030544777, AKOS030619920, Tox21_111511_1, DB04076, MCULE-8326019285, PS-3167, RP20238, SDCCGMLS-0065594.P001, SDCCGMLS-0065594.P002, NCGC00095622-04, AC-10518, AJ-70362, AK-96690, AN-23780, CC-29453, CJ-15841, KB-73995, SC-06274, SY012477, 6H-Purin-6-one, 1,7-dihydro- (9CI), 6H-Purin-6-one, 3,7-dihydro- (9CI), AB0008347, DB-029904, KB-157893, KB-249883, LS-127207, TL8004832, CS-0007792, FT-0627170, ST50160486, 1,7-Dihydro-6H-purin-6-one (Hypoxanthine), Discontinued. See H998503 or H998504", EN300-37579, Hypoxanthine, Vetec(TM) reagent grade, 98%, Hypoxsanthine (1,7-Dihydro-6H-purin-6-one), 2899-EP2269996A1, 2899-EP2270008A1, 2899-EP2270505A1, 2899-EP2292617A1, 2899-EP2292630A1, 2899-EP2295503A1, 2899-EP2302382A2, 2899-EP2302383A2, 2899-EP2316974A1, 68H940, C00262, Z-4186, 30233-EP2277880A1, 30233-EP2284165A1, 30233-EP2287167A1, 30233-EP2292604A2, 30233-EP2292610A1, 30233-EP2292615A1, 30233-EP2295433A2, 30233-EP2305825A1, 30233-EP2311464A1, AB00674258-01, SR-05000002375, I01-1127, S14-2816, SR-05000002375-1, W-104648, F1386-0269, Hypoxanthine, powder, BioReagent, suitable for cell culture, 8C229956-6BE8-4F8D-91B7-0AD1EC294077, Didanosine impurity A,, European Pharmacopoeia (EP) Reference Standard, Didanosine Related Compound A, United States Pharmacopeia (USP) Reference Standard, InChI=1/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10), 184856-40-4, 184856-41-5, 25991-07-5, 25991-08-6, 25991-09-7, 39464-15-8, 39464-17-0, 480-99-9, 6535-89-3, Hypoxanthine, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.

ID: 565

InChIKey: FDYFHDKFDSGDKM-MGPZMBRGSA-N
SMILES: CC(C)C1=CC2=C(C=C1)[C@]3(CCC[C@@](C3CC2)(C)CN)C.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16725076
synonyms found at PubChem are:
18-AMINOABIETA-8,11,13-TRIENE SULFATE, CHEMBL3039097, CCG-39972

ID: 566

InChIKey: FEBOTPHFXYHVPL-UHFFFAOYSA-N
SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16363
synonyms found at PubChem are:
BENPERIDOL, Anquil, 2062-84-2, Frenactil, Glianimon, Frenactyl, Concilium, Benzoperidol, McN-JR-4584, Benzperidol, Glianimon mite, R-4584, Anquil (VAN), Benperidolo [DCIT], Benperidol hydrochloride, Benzeridol, Benperidolum [INN-Latin], R 4584, Benperidol [USAN:INN:BAN], CB 8089, McN-JR 4584, UNII-97O6X78C53, 8089 C. B., EINECS 218-172-2, NSC 170982, BRN 0900981, 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1h-benzo[d]imidazol-2(3h)-one, 8089 C.B., C22H24FN3O2, FEBOTPHFXYHVPL-UHFFFAOYSA-N, NSC170982, 2H-Benzimidazol-2-one, 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl)-1,3-dihydro-, 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-, 97O6X78C53, NCGC00016602-01, CAS-2062-84-2, 1-(1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone, 4'-Fluor-4-(4-(2-oxo-1-benzimidazolinyl)piperidino)butyrophenon, 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-, 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1H-benzimidazol-2-one, DSSTox_CID_25364, DSSTox_RID_80827, DSSTox_GSID_45364, Benzperidol hydrochloride, Benperidolo, Benperidolum, 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-2-benzimidazolinone, 1-{1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl}-2-benzimidazolinone, 2-Benzimidazolinone, 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-, 3-[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl]-1H-benzimidazol-2-one, 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one, 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 983-42-6, Benquil, 1-1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl-2-benzimidazolinone, 1-1-[3-(p-Fluorobenzoyl)propyl]-4-piperidyl-2-benzimidazolinone, 1-(1-(4-(4-Fluorophenyl)-4-oxobutyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one, Anquil hydrochloride, Prestwick_778, Anquil (TN), Frenactyl hydrochloride, AC1Q4NJZ, Benperidol (USAN/INN), Prestwick0_000484, Prestwick1_000484, Prestwick2_000484, Prestwick3_000484, D0X7QQ, AC1L27SU, BSPBio_000347, 5-24-02-00375 (Beilstein Handbook Reference), MLS002153837, SCHEMBL122650, SPBio_002268, BPBio1_000383, CHEMBL297302, GTPL9215, DTXSID7045364, BDBM81492, CHEBI:93403, CTK4E4730, KS-00002WVI, MolPort-019-993-885, 2-Benzimidazolinone, hydrochloride, HMS1569B09, HMS2096B09, HMS2235H20, HMS3374B03, HMS3713B09, ZINC9232411, Tox21_110517, BDBM50183266, NSC_16363, NSC169873, PDSP1_000835, PDSP2_000822, AKOS016339645, Tox21_110517_1, API0001507, CCG-220484, DB12867, KS-1335, MCULE-4111012284, NSC-169873, NSC-170982, VZ21069, NCGC00016602-02, NCGC00016602-04, 8089 C.B, AC-12200, AN-50195, LS-33249, SC-75880, SMR001233200, CAS_2062-84-2, 8089 C. B, DB-045313, KB-151621, 2-Benzimidazolinone, hydrochloridemonohydrate, FT-0634013, ST50993924, WLN: T56 BMVNJ D- DT6NTJ A3VR DF, D02627, 062B842, A814756, L000947, SR-01000841254, 2H-Benzimidazol-2-one,3-dihydro-, monohydrochloride, SR-01000841254-2, BRD-K79425933-001-03-6, {1-1-[3-(p-Fluorobenzoyl)propyl]-4-piperidyl-2-benzimidazolinone}, 1-[1-[3-(p-Fluorbenzoyl)propyl]-4-piperidyl]-2-benzimidazolinon, 2-Benzimidazolinone, {1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-}, gamma-[4-(2-oxo-1-benzimidazolinyl)-piperidino]-p-fluorobutyrophenone, 1-[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl]-3H-benzoimidazol-2-one, 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl}-3-hydrobenzimidazol-2-one, 1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1H-benzo[d] imidazol-2(3H)-one, 2H-Benzimidazol-2-one,1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-, 3-[1-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]piperidin-4-yl]-1H-benzimidazol-2-one, 2-Benzimidazolinone, {1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-,} hydrochloridemonohydrate, 2H-Benzimidazol-2-one, {1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-}

ID: 567

InChIKey: FEFFSKLJNYRHQN-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)C(CCC(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 92225
synonyms found at PubChem are:
Phthalyl-DL-glutamic Acid, 2-Phthalimidoglutaric acid, 2301-52-2, 6349-98-0, 2-(1,3-dioxoisoindolin-2-yl)pentanedioic acid, Glutamic acid, phthalyl-, Phthaloyl-dl-glutamic acid, NPLG, Glutaric acid, 2-phthalimido-, N-Phthalylglutamic acid, Ba 2733, N-Phthalyl-dl-glutaminsaure, L-Glutamic acid, N-phthaloyl-, NSC43131, Glutaric acid, 2-phthalimido-, DL-, Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)pentanedioic acid, Phthalylglutamic acid, C13H11NO6, N-Phthalyl-dl-glutamate, N-Phthalyl-D,L-glutamic acid, PHTHALYL-DL-GLUTAMICACID, NSC-43131, EINECS 218-952-2, EINECS 228-754-8, NSC 43131, N-Phthalyl-DL-glutaminsaure [German], N-Phtaloylglutamic acid, 2-Phthalimidoglutaricacid, AC1L3NOG, AC1Q5SBN, Maybridge1_001721, N-Phtaloyl-DL-glutamic acid, N-Phthalyl-DL-glutamic acid, Oprea1_496228, CHEMBL71315, SCHEMBL411110, 2-Phthalimidylpentanedioic acid, CTK8B4029, HMS546G05, FEFFSKLJNYRHQN-UHFFFAOYSA-N, MolPort-001-840-723, 2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)glutaric acid, HMS3262P14, HMS3371P17, 2-(1,3-Dihydro-1,3-dioxy-2H-isoindole-2-yl)pentanedioicacid, AC1Q7573, ALBB-024228, KS-000017WI, Tox21_500956, 7639AH, ANW-43724, NSC120849, AKOS003236965, AKOS016050349, (L)-2-PHTHALIMIDOGLUTARIC ACID, CCG-205037, LP00956, MCULE-3857234778, NSC 120849, NSC-120849, TRA0084664, NCGC00261641-01, LS-72003, NCI60_003999, KB-285749, TR-010757, A8743, EU-0100956, FT-0634187, P0338, R1478, ST45002105, 2-(1,3-dioxo-2-isoindolyl)pentanedioic acid, 2-(1,3-dioxoisoindol-2-yl)pentanedioic acid, P 1801, A816489, SR-01000075452, I14-5745, SR-01000075452-1, 2-(1,3-dioxobenzo[c]azolidin-2-yl)pentanedioic acid, 2-[1,3-bis(oxidanylidene)isoindol-2-yl]pentanedioic acid, Pentanedioic acid,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 2-(1,3-Dihydro-1,3-dioxy-2H-isoindole-2-yl)pentanedioic acid, 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentanedioic acid, (1)-2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)glutaric acid, 942911-47-9

ID: 568

InChIKey: FEGCPHIPSRBREU-HVATVPOCSA-N
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(C=C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5283972
synonyms found at PubChem are:
Lithocholenic acid, UNII-BAO73Q70IY, BAO73Q70IY, 3alpha-Hydroxy-5beta-chol-11-en-24-oic Acid, 11,(5beta)-Cholenic acid-3alpha-ol, 1053-37-8, LITHOCHOL-11-ENIC ACID, AC1NR3GI, CHEMBL3138720, 11-Cholenic acid, 3alpha-hydroxy-, LMST04010210, CHOL-11-EN-24-oic acid, 3-hydroxy-, (3alpha,5beta)-, (4R)-4-[(3R,5R,8S,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

ID: 569

InChIKey: FEGVSPGUHMGGBO-VOTSOKGWSA-N
SMILES: COC1=CC=CC=C1/C=C/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 734154
synonyms found at PubChem are:
2-Methoxycinnamic acid, 6099-03-2, 1011-54-7, 3-(2-Methoxyphenyl)acrylic acid, trans-2-Methoxycinnamic acid, (2E)-3-(2-methoxyphenyl)acrylic acid, (E)-3-(2-Methoxyphenyl)acrylic acid, (2E)-3-(2-methoxyphenyl)prop-2-enoic acid, o-Methoxycinnamic acid, (E)-3-(2-Methoxyphenyl)-2-propenoic acid, (E)-o-Methoxycinnamic acid, trans-O-Methyl-o-coumaric Acid, Cinnamic acid, o-methoxy-, UNII-J77SK1Y4MY, 3-(2-methoxyphenyl)prop-2-enoic acid, J77SK1Y4MY, 2-Propenoic acid, 3-(2-methoxyphenyl)-, FEGVSPGUHMGGBO-VOTSOKGWSA-N, 2-Propenoic acid, 3-(2-methoxyphenyl)-, (E)-, COUMARINIC ACID METHYL ETHER, NSC638141, 2-Methoxy-cinnamic acid, (E)-3-(2-methoxyphenyl)prop-2-enoic acid, 3-(2-Methoxyphenyl)-2-propenoic acid, (2E)-3-(2-Methoxyphenyl)-2-propenoic acid #, FEGVSPGUHMGGBO-UHFFFAOYSA-N, 3-(2-Methoxy-phenyl)-acrylic acid, EINECS 213-785-1, 2-Methoxy-zimtsaure, 2-Propenoic acid, 3-(2-methoxyphenyl)-, (2E)-, AI3-11206, AC1Q5RAW, AC1LED48, AC1Q5T9F, 2-Methoxybenzeneacrylic acid, (E)-2-methoxycinnamic acid, CHEMBL95203, trans-O-Methyl-o-cumaric Acid, ARONIS023687, trans-ortho-methoxycinnamic acid, 3-(2-Methoxyphenyl)acrylicacid, CHEBI:93692, NSC8135, CHEBI:136676, MolPort-000-860-922, MolPort-004-288-328, HMS1748N22, ZINC149577, ALBB-007553, NSC-8135, EINECS 228-047-4, 2-Methoxycinnamic acid, >=97.0%, 7327AC, BBL013998, HTS001422, SBB043620, STK411567, AKOS000120225, BS-3963, NE10312, NSC 638141, NSC-638141, RL00073, RP16856, RTR-000333, (E)-3-(2-Methoxy-phenyl)-acrylic acid, AJ-12583, KB-26646, KB-68941, AB0047012, TC-170475, TR-000333, M0449, R1906, ST24041404, ST45026678, trans-3-(2-Methoxyphenyl)prop-2-enoic acid, Y1994, 2-Methoxycinnamic acid, predominantly trans, 98%, I04-1667, I04-9969, J-008350, J-509858, I04-13686, CD9AA602-23B3-4A72-B198-69C984F1152A

ID: 570

InChIKey: FEGZBVFKDOUDFN-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CN(CC2=NC=CN2)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957448
synonyms found at PubChem are:
Antozoline hydrochloride, EU-0100105, CHEMBL1487371, Tox21_500105, CCG-221409, LP00105, NCGC00093602-01, NCGC00260790-01, A 9899, SR-01000075257, SR-01000075257-1

ID: 571

InChIKey: FEWJPZIEWOKRBE-UHFFFAOYSA-N
SMILES: C(C(C(=O)O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 875
synonyms found at PubChem are:
DL-Tartaric acid, 2,3-Dihydroxysuccinic acid, 2,3-Dihydroxybutanedioic acid, tartaric acid, 133-37-9, Racemic acid, Uvic acid, 526-83-0, Traubensaure, Paratartaric acid, Paratartaric aicd, DL-Tartrate, Racemic tartaric acid, Resolvable tartaric acid, Tartaric acid D,L, (2R,3R)-Tartaric acid, BUTANEDIOIC ACID, 2,3-DIHYDROXY-, Threaric acid, (+)-Tartaric acid, Acidum tartaricum, CADAVERINE TARTRATE, (.+-.)-Tartaric acid, NSC62778, (2RS,3RS)-Tartaric acid, NSC 148314, CHEBI:15674, tartrate, (2R,3R)-2,3-Dihydroxybernsteinsaeure, Weinsteinsaeure, dl-2,3-dihydroxybutanedioic acid, Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-, FEWJPZIEWOKRBE-UHFFFAOYSA-N, Natural tartaric acid, (+-)-Tartaric acid, 2,3-Dihydrosuccinic acid, Tartaric acid, L-(+)-, Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-rel-, FEMA No. 3044, CCRIS 8978, Butanedioic acid, 2,3-dihydroxy-(R*,R*)-(.+/-.)-, EINECS 205-105-7, L-(+)-TARTARIC ACID, ACS, NSC155080, d-2,3-dihydroxysuccinic acid, (R,R)-(+)-Tartaric acid, L-2,3-Dihydroxybutanedioic acid, (+)-(2R,3R)-Tartaric acid, (+) tartaric acid, (-) tartaric acid, 1,2-Dihydroxyethane-1,2-dicarboxylic acid, 1,2-dicarboxylic acid, WLN: QVYQYQVQ, (-) D-Tartaric acid, ACMC-209qpg, Sal tartar (Salt/Mix), Tartaric acid, (DL)-, Butanedioic acid, 2,3-dihydroxy-, (2R,3S)-rel-, Butanedioic acid, 2,3-dihydroxy-, [S-(R*,R*)]-, Malic acid, 3-hydroxy-, laevo-(+)-tartaric acid, dextro,laevo-tartaric acid, Succinic acid,3-dihydroxy, Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-(+-)-, SCHEMBL848, ACMC-209cz3, bmse000167, AC1Q76KC, Succinic acid,3-dihydroxy-, (.+/-.)-Tartaric acid, Butanedioic acid, 2,3-dihydroxy-, (theta,theta)-(+-)-, DSSTox_CID_26986, DSSTox_RID_82036, 2,3-dihydroxy-succinic acid, DSSTox_GSID_46986, Oprea1_827092, TARTARIC ACID, (L), 2-Aminoethanethiol Bitartrate, Tartaric acid, (.+-.)-, Butanedioic acid,3-dihydroxy-, AC1L1A82, CHEMBL333714, Dihydroxysuccinic acid, (DL)-, Tartaric acid, (.+/-.)-, DTXSID5046986, CTK7J6041, L+Tartaric Acid FCC, NF, USP, MolPort-001-779-714, 2,3-bis(oxidanyl)butanedioic acid, D -2,3-Dihydroxybutanedioic acid, HMS3370M15, L -2,3-Dihydroxybutanedioic acid, DL-Tartaric acid, 99% 250g, (+)-2,3-dihydroxybutanedioic acid, (S,S)-Tartaric acid;Tartaric acid, BCP14303, Tox21_302052, BBL011588, MFCD00071626, NSC-62778, NSC133735, NSC148314, NSC608773, STK387106, 2,3-Dihydroxysuccinic acid, (DL)-, 3-carboxy-2,3-dihydroxypropanoic acid, AKOS000120086, AKOS016844048, L-(+)-Tartaric acid, ACS 100g, MCULE-3867000095, NE11122, NSC-133735, NSC-148314, NSC-608773, RL01525, RL03940, RP21326, TRA0007150, TRA0043481, SMP2_000051, d-.alpha.,.beta.-Dihydroxysuccinic acid, NCGC00256063-01, AN-20550, AN-23077, AN-23285, AN-23531, AN-24126, AS-10983, BC204248, CAS-133-37-9, NCI60_001102, (+)-2,3-dihydroxy-1,4-butanedioic acid, DB-053495, KB-164119, LS-164466, AM20110247, FT-0625514, FT-0656080, ST24027285, (+/-)-2,3-dihydroxy-1,4-butanedioic acid, 1467-EP2269610A2, 1467-EP2269986A1, 1467-EP2269988A2, 1467-EP2269989A1, 1467-EP2269990A1, 1467-EP2270003A1, 1467-EP2270006A1, 1467-EP2270008A1, 1467-EP2270011A1, 1467-EP2270014A1, 1467-EP2270505A1, 1467-EP2272516A2, 1467-EP2272537A2, 1467-EP2272822A1, 1467-EP2272827A1, 1467-EP2272835A1, 1467-EP2272843A1, 1467-EP2272844A1, 1467-EP2275401A1, 1467-EP2275411A2, 1467-EP2275413A1, 1467-EP2275414A1, 1467-EP2277507A1, 1467-EP2277848A1, 1467-EP2277858A1, 1467-EP2277866A1, 1467-EP2277867A2, 1467-EP2280003A2, 1467-EP2280009A1, 1467-EP2281559A1, 1467-EP2281563A1, 1467-EP2281817A1, 1467-EP2281819A1, 1467-EP2281823A2, 1467-EP2284149A1, 1467-EP2284160A1, 1467-EP2284169A1, 1467-EP2284178A2, 1467-EP2284179A2, 1467-EP2286795A1, 1467-EP2287147A2, 1467-EP2287154A1, 1467-EP2287155A1, 1467-EP2287156A1, 1467-EP2287160A1, 1467-EP2287161A1, 1467-EP2287162A1, 1467-EP2289510A1, 1467-EP2289518A1, 1467-EP2289879A1, 1467-EP2289883A1, 1467-EP2289885A1, 1467-EP2289890A1, 1467-EP2289893A1, 1467-EP2292227A2, 1467-EP2292231A1, 1467-EP2292234A1, 1467-EP2292592A1, 1467-EP2292611A1, 1467-EP2292612A2, 1467-EP2292617A1, 1467-EP2292619A1, 1467-EP2295055A2, 1467-EP2295402A2, 1467-EP2295406A1, 1467-EP2295414A1, 1467-EP2295416A2, 1467-EP2295418A1, 1467-EP2295424A1, 1467-EP2295433A2, 1467-EP2298731A1, 1467-EP2298734A2, 1467-EP2298735A1, 1467-EP2298742A1, 1467-EP2298746A1, 1467-EP2298747A1, 1467-EP2298748A2, 1467-EP2298755A1, 1467-EP2298758A1, 1467-EP2298759A1, 1467-EP2298763A1, 1467-EP2298767A1, 1467-EP2298768A1, 1467-EP2298772A1, 1467-EP2298777A2, 1467-EP2298779A1, 1467-EP2301544A1, 1467-EP2301922A1, 1467-EP2301931A1, 1467-EP2301937A1, 1467-EP2301940A1, 1467-EP2305219A1, 1467-EP2305248A1, 1467-EP2305257A1, 1467-EP2305633A1, 1467-EP2305636A1, 1467-EP2305641A1, 1467-EP2305646A1, 1467-EP2305651A1, 1467-EP2305653A1, 1467-EP2305655A2, 1467-EP2305659A1, 1467-EP2305663A1, 1467-EP2305664A1, 1467-EP2305672A1, 1467-EP2305673A1, 1467-EP2305675A1, 1467-EP2305676A1, 1467-EP2305679A1, 1467-EP2305683A1, 1467-EP2308839A1, 1467-EP2308841A2, 1467-EP2308849A1, 1467-EP2308850A1, 1467-EP2308851A1, 1467-EP2308854A1, 1467-EP2308857A1, 1467-EP2308861A1, 1467-EP2308869A1, 1467-EP2308871A1, 1467-EP2308872A1, 1467-EP2308873A1, 1467-EP2308875A1, 1467-EP2311453A1, 1467-EP2311801A1, 1467-EP2311802A1, 1467-EP2311803A1, 1467-EP2311807A1, 1467-EP2311809A1, 1467-EP2311810A1, 1467-EP2311811A1, 1467-EP2311818A1, 1467-EP2311821A1, 1467-EP2311831A1, 1467-EP2311834A1, 1467-EP2311837A1, 1467-EP2311839A1, 1467-EP2311842A2, 1467-EP2314295A1, 1467-EP2314574A1, 1467-EP2314575A1, 1467-EP2314576A1, 1467-EP2314584A1, 1467-EP2314585A1, 1467-EP2314586A1, 1467-EP2314587A1, 1467-EP2314588A1, 1467-EP2314589A1, 1467-EP2314593A1, 1467-EP2316457A1, 1467-EP2316458A1, 1467-EP2316459A1, 1467-EP2316470A2, 1467-EP2316825A1, 1467-EP2316826A1, 1467-EP2316827A1, 1467-EP2316828A1, 1467-EP2316829A1, 1467-EP2316831A1, 1467-EP2316832A1, 1467-EP2316833A1, 1467-EP2316834A1, 1467-EP2316835A1, 1467-EP2316836A1, 1467-EP2316837A1, 1467-EP2371814A1, 1467-EP2374454A1, 1467-EP2374780A1, 1467-EP2374781A1, 1467-EP2380874A2, A22830, A22866, Butanedioic acid,3-dihydroxy- [R-(R*,R*)]-, 133D379, A829202, I04-0225, I04-1071, I04-1113, Butanedioic acid,3-dihydroxy-, (R*,R*)-(.+-.)-, I14-11535, F2191-0230, Z1258943354, 1,2-Dihydroxyethane-1,2-dicarboxylic acid;2,3-Dihydrosuccinic acid, Copper, mixt. with [R-(R*,R*)]-2,3-dihydroxybutanedioic acid monopotassium salt

ID: 572

InChIKey: FFGPTBGBLSHEPO-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2554
synonyms found at PubChem are:
carbamazepine, 298-46-4, Tegretol, 5H-Dibenzo[b,f]azepine-5-carboxamide, Carbamazepen, Carbazepine, Finlepsin, Biston, Equetro, Carbamezepine, Tegretal, Epitol, Carbatrol, Neurotol, Timonil, 5H-Dibenz[b,f]azepine-5-carboxamide, Karbamazepin, Stazepine, Telesmin, Lexin, Tegretol-Xr, Carbamazepina, Carbamazepinum, Carbamazepin, Amizepin, Bipotrol, Teril, 5-Carbamyl-5H-dibenzo(b,f)azepine, 5-Carbamoyl-5H-dibenzo(b,f)azepine, Geigy 32883, Calepsin, Carnexiv, Stazepin, 5-Carbamoyl-5H-dibenz(b,f)azepine, 5H-Dibenz(b,f)azepine-5-carboxamide, benzo[b][1]benzazepine-11-carboxamide, 5-Carbamoyl-5H-dibenz[b,f]azepine, G 32883, G-32883, Carbamazepan, Carbelan, Sirtal, Tegretol Cr, Carbamazepinum [INN-Latin], Carbamazepina [INN-Spanish], NSC 169864, CHEBI:3387, UNII-33CM23913M, HSDB 3019, FFGPTBGBLSHEPO-UHFFFAOYSA-N, EINECS 206-062-7, CHEMBL108, BRN 1246090, 5-Carbamyldibenzo(b,f)azepine, MLS000069652, 5-Carbamoyldibenzo(b,f)azepine, Carbamazepine Hydrochloride, dibenzo[b,f]azepine-5-carboxamide, NSC169864, 33CM23913M, NCGC00015234-11, CAS-298-46-4, SMR000058201, carbamazepine hydrate, DSSTox_CID_2731, DSSTox_RID_76704, DSSTox_GSID_22731, Q-200792, Carbazepin, Amizepine, 2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene-2-carboxamide, SMR001227191, Carbamazepine Anhydrous, Carbamazepine Phosphate, SR-01000000229, Carbatrol extended-release, Atretol, Trimonil, Neurotop retard, Novo-Carbamaz, Nu-Carbamazepine, Apo-Carbamazepine, Tegretol Chewtabs, Taro-Carbamazepine, Tegretol (TN), Prestwick_104, carbamazepine sulfate, Equetro (TN), Carbamazepine [USAN:INN:BAN:JAN], carbamazepine tartrate, Carbamazepine, powder, Taro-Carbamazepine Cr, Opera_ID_72, Spectrum_000096, Carbamazepine [USAN:USP:INN:BAN:JAN], carbamazepine (Tegretol), AC1L1DXT, AC1Q4ZSU, AC1Q4ZSV, Prestwick0_000052, Prestwick1_000052, Prestwick2_000052, Prestwick3_000052, Spectrum2_000125, Spectrum3_000325, Spectrum4_000262, Spectrum5_000936, Carbamazepine (Carbatrol), Lopac-C-4024, ChemDiv1_018966, CBChromo1_000350, D04MSM, Epitope ID:174842, Iminostilbene-N-carboxamide, Lopac0_000292, Oprea1_790775, SCHEMBL21639, BSPBio_000203, BSPBio_001929, Carbamazepine (iv, epilepsy), KBioGR_000724, KBioSS_000516, MLS001055475, MLS001074172, MLS002548877, BIDD:GT0479, DivK1c_000388, DivK1c_003750, SPECTRUM1500159, SPBio_000170, SPBio_002124, CARBAMAZEPINE, U.S.P., BPBio1_000225, GTPL5339, ZINC4785, DTXSID4022731, SCHEMBL19838283, HMS501D10, HMS640O02, KBio1_000388, KBio2_000516, KBio2_003084, KBio2_005652, KBio3_001149, WLN: T C676 BNJ BVZ, AOB5783, Carbamazepine (JP17/USP/INN), SPD-417, Carbamazepine, analytical standard, MolPort-000-710-574, MolPort-023-220-275, NINDS_000388, HMS1568K05, HMS1920I17, HMS2090M07, HMS2091O19, HMS2095K05, HMS2233G16, HMS3039K09, HMS3259B21, HMS3260L06, HMS3372J13, HMS3657G03, HMS3712K05, Pharmakon1600-01500159, 85756-57-6 (di-hydrate), ACT02606, BCP21380, HY-B0246, KS-00000KI8, 5-Carbomoyl-5H-dibenzo(b,f)azepine, Tox21_110104, Tox21_202273, Tox21_300195, Tox21_500292, BBL005372, BDBM50003659, BG0497, CCG-38931, GP8250, MFCD00005073, NSC755920, s1693, STK177357, STL453548, 11-benzo[b][1]benzazepinecarboxamide, 5H-Dibenz[b,f]azepine-5-carboxamine, Carbamazepine 1.0 mg/ml in Methanol, AKOS003235644, AKOS025397243, IMED104589831, Tox21_110104_1, 5H-Dibenz[b,f]azepine-5- carboxamide, AC-9538, AN-6325, Carbamazepine (iv, epilepsy), Lundbeck, CS-2225, DB00564, KS-5146, LP00292, MCULE-9121567287, NC00679, NSC-169864, NSC-755920, 5H-Dibenz[ b, f]azepine-5-carboxamide, CDS1_002710, IDI1_000388, 5H-Dibenzo[b,f]azepine-5-carboxamide #, NCGC00015234-01, NCGC00015234-02, NCGC00015234-03, NCGC00015234-04, NCGC00015234-05, NCGC00015234-06, NCGC00015234-07, NCGC00015234-08, NCGC00015234-09, NCGC00015234-10, NCGC00015234-12, NCGC00015234-13, NCGC00015234-14, NCGC00015234-15, NCGC00015234-16, NCGC00015234-19, NCGC00023877-03, NCGC00023877-04, NCGC00023877-05, NCGC00023877-06, NCGC00023877-07, NCGC00023877-08, NCGC00253982-01, NCGC00259822-01, NCGC00260977-01, AJ-08227, AJ-08230, AK116064, BC200975, CC-25382, CC-25383, CPD001227191, H495, LS-60362, SAM002264603, SC-16243, ST075773, ZB000594, (z)-5h-dibenzo[b,f]azepine-5-carboxamide, SBI-0050280.P004, 5H-dibenzo[b,f]azepine-5-carboximidic acid, AB0070254, AB1009530, KB-246109, ST2418853, EU-0100292, FT-0602927, FT-0696814, H2605, EN300-21678, BIM-0050280.0001, C 4024, C06868, Carbamazepine, meets USP testing specifications, D00252, AB00051931-17, AB00051931-18, AB00051931_19, AB00051931_20, A820074, C-13993, I06-0863, SR-01000000229-2, SR-01000000229-4, SR-01000000229-7, BRD-K71799949-001-06-7, Carbamazepine (iv, epilepsy), Ovation Pharmaceuticals, F0348-2551, Z2199879032, Dibenzo[b,f]azepine-5-carboxylic acid amide(Carbamazepine), 5H-dibenzo[b,f]azepine-5-carboxamide;Oxcarbazepine IMpurity A, Carbamazepine, British Pharmacopoeia (BP) Reference Standard, Carbamazepine, European Pharmacopoeia (EP) Reference Standard, Carbamazepine, United States Pharmacopeia (USP) Reference Standard, 2-azatricyclo[9.4.0.0;{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene-2-carboxamide, Carbamazepine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Carbamazepine, Pharmaceutical Secondary Standard; Certified Reference Material, Azapentacene; Sodium 5,12-dihydroazapentacene disulfonate; 5,12-Dihydroquinoxalino[2,3-b]phenazine sulfonate sodium salt

ID: 573

InChIKey: FFKUDWZICMJVPA-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)O)OP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3418
synonyms found at PubChem are:
fosfosal, 2-(Phosphonooxy)benzoic acid, 6064-83-1, Disdolen, Salicyl phosphate, o-Carboxyphenyl phosphate, 2-Carboxyphenyl phosphate, 2-Phosphonoxybenzoic acid, Phosphonoxybenzoic acid, o-(Phosphonooxy)benzoic acid, 2-Phosphonooxybenzoic acid, Fosfosal [INN], Benzoic acid, o-(phosphonooxy)-, Salicylic acid dihydrogen phosphate, UR 1521, 2-Phosphonoxybenzoesaeure, Fosfosalum [INN-Latin], Benzoic acid, 2-(phosphonooxy)-, NSC 46475, UR 1522, UNII-124X2V25W4, Salicylic acid phosphate, 2-Phosphonoxybenzoesaeure [German], EINECS 227-993-5, 2-Phosphonooxy-benzoic acid, BRN 2619142, CHEMBL287275, Fosfosal (INN), Salicylic acid, dihydrogen phosphate, 124X2V25W4, NCGC00016668-02, CAS-6064-83-1, DSSTox_CID_25394, DSSTox_RID_80851, DSSTox_GSID_45394, Fosfosalum, SR-01000872625, Aydolid, C7H7O6P, o-cpp cpd, Prestwick_30, Disdolen (TN), Aydolid (TN), o-carboxyphenylphosphate, Spectrum_001347, WLN: QVR BOPQQO, AC1Q6SKP, Prestwick0_000815, Prestwick1_000815, Prestwick2_000815, Prestwick3_000815, Spectrum2_001458, Spectrum3_000940, Spectrum4_001039, Spectrum5_001180, D0N3UL, AC1L1FW2, SCHEMBL23401, BSPBio_000709, KBioGR_001597, KBioSS_001827, 4-10-00-00142 (Beilstein Handbook Reference), 2-Carboxyphenylphosphoric acid, DivK1c_000048, SPECTRUM1502012, SPBio_001355, SPBio_002630, BPBio1_000781, Benzoic acid,2-(phosphonooxy)-, DTXSID9045394, CHEBI:94564, CTK5B1978, HMS500C10, KBio1_000048, KBio2_001827, KBio2_004395, KBio2_006963, KBio3_001980, FFKUDWZICMJVPA-UHFFFAOYSA-N, MolPort-003-666-393, NINDS_000048, HMS1570D11, HMS1921D06, HMS2097D11, HMS3714D11, Pharmakon1600-01502012, NSC46475, ZINC1678159, 2-Carboxyphenyl dihydrogen phosphate, Tox21_110554, BDBM50112448, CCG-39194, NSC-46475, NSC758155, phosphoric acid o-carboxyphenyl ester, AKOS015958782, Tox21_110554_1, MCULE-1086101121, NSC-758155, UR-1521, VZ33514, IDI1_000048, NCGC00016668-01, NCGC00016668-03, NCGC00016668-06, NCGC00094938-01, NCGC00094938-02, Benzoic acid, 2-(phosphonooxy)- (9CI), SBI-0051697.P002, LS-144311, AB00052254, FT-0626545, P1952, VU0243472-2, D07991, AB00052254_04, SR-01000872625-1, SR-01000872625-2, BRD-K28687144-001-02-0, F9995-1274, Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-

ID: 574

InChIKey: FFNMBRCFFADNAO-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 71405
synonyms found at PubChem are:
Pirenzepine dihydrochloride, Pirenzepine hydrochloride, 29868-97-1, Tabe, Pirenzepine HCl, Bisvanil, Leblon, Maghen, Pirenzepine 2HCl, Pirenzepinehydrochloride, LS 519 dihydrochloride, UNII-10YM403FLS, LS 519 cl2, LS 519Cl2, EINECS 249-907-5, Pirenzepine hydrochloride [USAN:JAN], Pirenzepine (dihydrochloride), 10YM403FLS, 5,11-Dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one dihydrochloride, 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride, 6,11-Dihydro-11-((4-methyl-1-piperazinyl)acetyl)-5H-pyrido(2,3-b)(1,4)benzodiazepin-6-on dihydrochlorid, pircfar, CHEBI:32014, 11-(2-(4-methylpiperazin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one dihydrochloride, 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride, 5,11-Dihydro-11-((4-methylpiperazin-1-yl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one dihydrochloride, 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-, dihydrochloride, SR-01000000220, Prestwick_400, 5,11-Dihydro-11-, AC1L2G3Q, AC1Q3B3J, Pirenzepine, Dihydrochloride, SCHEMBL41704, SPECTRUM1501138, C19H21N5O2.2HCl, CHEMBL1531864, CTK8G2443, KS-00000GXM, C19H21N5O2.HCl.H2O, Pirenzepine hydrochloride (USAN), FFNMBRCFFADNAO-UHFFFAOYSA-N, MolPort-003-666-363, HMS1568I20, HMS1921J05, BCP12435, Tox21_500962, BG0383, CCG-38974, GP0823, LS 519, MFCD00055214, AKOS024456369, CS-6975, LP00962, LS-519-C12, NCGC00094263-01, NCGC00094263-02, NCGC00094263-03, NCGC00261647-01, AK162585, AN-14256, AS-15182, CC-33823, HY-17037, O383, LS-133129, B6582, EU-0100962, FT-0619757, ST24048937, D01297, M-1036, P 7412, 868P971, J-017673, Pirenzepine dihydrochloride, >=98% (TLC), powder, SR-01000000220-2, SR-01000000220-4, SR-01000000220-7, [(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride, (5,11-Dihydro-11-[(4-methyl-1-piperazinyl)-acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one), 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)-acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-,dihydrochloride, AKOS015896140, I06-1655, 11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride

ID: 575

InChIKey: FFWOKTFYGVYKIR-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 10639
synonyms found at PubChem are:
Physcion, 521-61-9, Physcione, Parietin, Rheochrysidin, Emodin 3-methyl ether, 1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione, NSC 251670, Emodin monomethyl ether, Emodin-3-methyl ether, Methoxyemodin, Parienin, UNII-H6PT94IV61, 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone, CCRIS 4399, 1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione, EINECS 208-315-7, Rheochrysidin (Physcione), NSC251670, BRN 1915778, 1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone, CHEMBL42624, H6PT94IV61, ANTHRAQUINONE, 1,8-DIHYDROXY-3-METHOXY-6-METHYL-, 1,8-Dihydroxy-3-methoxy-6-methyl-anthraquinone, Q-100587, 1,8-dihydroxy-3-methoxy-6-methyl-anthracene-9,10-dione, 9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl-, fischione, rheochrysidi), Physcion(e), Physcion,(S), Spectrum_001782, 9,10-dione, SpecPlus_000471, AC1L1VMS, PHYSCION (SENNA), Spectrum2_000503, Spectrum3_001829, Spectrum4_000909, Spectrum5_001742, Rheochrysidin - Physcione, BSPBio_003477, KBioGR_001378, KBioSS_002265, Physcion, analytical standard, DivK1c_006567, SCHEMBL486155, SPECTRUM1504070, SPBio_000425, MEGxm0_000018, CHEBI:38167, CTK8E3154, KBio1_001511, KBio2_002264, KBio2_004832, KBio2_007400, KBio3_002981, DTXSID20200101, FFWOKTFYGVYKIR-UHFFFAOYSA-N, MolPort-000-165-355, HMS3656I15, Physcion, >=98.0% (TLC), KS-00000NK5, ZINC3978794, BDBM50005886, CCG-38713, CP-228, CP0083, MFCD00017374, s2395, AKOS015905689, AC-7979, AN-8462, KS-5385, LS-2148, NSC-251670, RL03921, SDCCGMLS-0066772.P001, NCGC00096075-01, NCGC00096075-02, NCGC00096075-03, 9, 1,8-dihydroxy-3-methoxy-6-methyl-, AJ-47575, AK160252, AS-15488, BC216289, NCI60_002011, P564, SC-46573, AX8008593, TR-018534, FT-0657510, N1853, ST24048914, 1,8-dihydroxy-3-methoxy-6-methylanthracene-, 1,8-dihydroxy-6-methoxy-3-methylanthraquinone, Anthraquinone,8-dihydroxy-3-methoxy-6-methyl-, C17045, 521P619, A828949, SR-05000002537, SR-05000002537-1, 8,9-dihydroxy-3-methyl-6-methoxy-1,10-anthraquinone, 8,9-dihydroxy-6-methyl-3-methoxy-1,10-anthraquinone, BRD-K67772619-001-03-6, Physcion; Physcione; Parietin; Emodin 3-methyl ether, 1,8-Dihydroxy-3-methoxy-6-methylanthra-9,10-quinone #, 3-methoxy-6-methyl-1,8-bis(oxidanyl)anthracene-9,10-dione, 9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl- (9CI)

ID: 576

InChIKey: FGANMDNHTVJAHL-UHFFFAOYSA-N
SMILES: CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 73416
synonyms found at PubChem are:
EVOXINE, NSC94653, 522-11-2, CHEBI:4952, 1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methylbutane-2,3-diol, 2,3-Butanediol, 1-((4,8-dimethoxyfuro(2,3-b)quinolin-7-yl)oxy)-3-methyl-, (+)-, 1-(4,8-dimethoxyfurano[2,3-b]quinolin-7-yloxy)-3-methylbutane-2,3-diol, 1-(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methyl-butane-2,3-diol, Haplophytin B, 2,3-Butanediol, 1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-, (+)-, Prestwick_160, NSC 94653, Spectrum_001734, SpecPlus_000604, AC1L2JTP, Prestwick0_000665, Prestwick1_000665, Prestwick2_000665, Spectrum2_001625, Spectrum3_000985, Spectrum4_001111, Spectrum5_001911, CBMicro_015580, C10670, Cambridge id 5255766, BSPBio_002649, KBioGR_001582, KBioSS_002214, MLS000104988, DivK1c_006700, SPECTRUM1504020, SPBio_001689, SPBio_002650, AC1Q4Y62, CHEMBL1416006, SCHEMBL10200371, CTK4J5605, KBio1_001644, KBio2_002214, KBio2_004782, KBio2_007350, KBio3_001869, 2,3-Butanediol,1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-, (2R)-, MolPort-002-507-400, HMS1570E11, HMS2330P21, HMS3373D19, BBL028782, CCG-38745, NSC-94653, STL372642, AKOS005224064, MCULE-3132893909, SDCCGMLS-0005807.P002, (+)-1-((4,8-Dimethoxyfuro(2,3-b)quinolin-7-yl)oxy)-3-methyl-2,3-butanediol, NCGC00017284-02, NCGC00017284-03, NCGC00017284-04, NCGC00017284-05, NCGC00087752-02, NCGC00087752-03, 4CN-1332, NCI60_042106, SMR000054917, ST005174, BIM-0015493.P001, SR-01000624769, SR-01000624769-3, BRD-A99268498-001-03-5, BRD-A99268498-001-06-8, 1-(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol, 1-[(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-2,3-butanediol

ID: 577

InChIKey: FGICTAQFCLUOBH-UHFFFAOYSA-N
SMILES: CN(C1=CC(=O)C=CC1=O)NO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5353574
synonyms found at PubChem are:
dephostatin, 151606-30-3, 2-(Methylnitrosoamino)-1,4-benzenediol, 1,4-Benzenediol, 2-(methylnitrosoamino)-, 2-[(hydroxyamino)-methylamino]cyclohexa-2,5-diene-1,4-dione, Lopac-D-8065, AC1NS4C2, Lopac0_000403, CHEMBL269733, SCHEMBL3893046, SCHEMBL12305062, CTK8E8374, HMS3261A08, ZINC3872250, 2-(N-methyl-N-nitroso)hydroquinone, Tox21_500403, HSCI1_000163, AKOS006271953, 2-(N-methyl-N-nitroso)-hydro-quinone, CCG-204496, LP00403, 1,4-Dihydroxy-N-methyl-N-nitrosoaniline, NCGC00015372-01, NCGC00015372-02, NCGC00015372-03, NCGC00015372-04, NCGC00093830-01, NCGC00093830-02, NCGC00261088-01, 1,4-Benzenediol,2-(methylnitrosoamino)-, KB-49655, LS-30000, 1,4-Dihydroxy-N-methyl-N-nitroso-aniline, RT-012251, D8065, EU-0100403, FT-0694317, D 8065, N-(2,5-dihydroxyphenyl)-N-methylnitrous amide, SR-01000075834, J-008825, SR-01000075834-1

ID: 578

InChIKey: FGNUNVVTHHKDAM-UHFFFAOYSA-N
SMILES: C1CNCC(=C1)C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957555
synonyms found at PubChem are:
Guvacine hydrochloride, 6027-91-4, 1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride, 1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid hydrochloride, MLS000859975, SR-01000075614, SMR000326834, Guvacine HCl, SPECTRUM1502126, SCHEMBL1057880, CHEMBL1256362, CTK7I6002, FGNUNVVTHHKDAM-UHFFFAOYSA-N, MolPort-003-665-602, ZX-CM014693, Tox21_500571, 8985AB, ACM498964, ANW-67778, BN0243, CCG-38871, MFCD00055191, AKOS015849631, AKOS025243938, LP00571, MCULE-9382105537, TRA0072680, NCGC00093955-01, NCGC00093955-02, NCGC00093955-03, NCGC00261256-01, CS-13242, EN000938, AX8236874, HY-100809, KB-123426, TR-020835, B6229, CS-0020452, EU-0100571, FT-0669083, G-007, Y1163, Guvacine hydrochloride, >=97% (NMR), solid, 1,2,5,6-Tetrahydronicotinic acid hydrochloride, Z-2043, GUVACINE HYDROCHLORIDE >96% \ GABA UPTAK, GUVACINE HYDROCHLORIDE gt96% \ GABA UPTAK, SR-01000075614-1, SR-01000075614-3, SR-01000075614-6, 1,2,5,6-Terahydropyridine-3-carboxylic acid hydrochloride, 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, hydrochloride salt

ID: 579

InChIKey: FHHSEFRSDKWJKJ-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC(=C(C=C3)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5317284
synonyms found at PubChem are:
6-Methoxyluteolin, 520-11-6, Nepetin, EUPAFOLIN, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one, Eurafolin, UNII-I3O7LF3GED, I3O7LF3GED, CHEMBL172350, NSC122416, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one, SMR000440634, Pedaltin, NSC 122416, AC1NSVCV, D03MLC, MLS000728561, MLS000877025, SCHEMBL828390, MEGxp0_000458, ACon1_000516, BDBM23412, cid_5317284, DTXSID10199959, FHHSEFRSDKWJKJ-UHFFFAOYSA-N, MolPort-000-774-377, REGID_for_CID_5317284, HMS2218H11, ZINC5998557, 7300AB, LMPK12111230, AKOS016009654, MCULE-7564407072, VA10871, NCGC00163594-01, NCGC00163594-02, NCGC00169005-01, AJ-55455, AK111278, Flavone,4',5,7-tetrahydroxy-6-methoxy-, ST081374, 6-methoxy 5,7,3',4'-tetrahydroxyflavone, AX8109560, KB-221429, 4CH-024481, FT-0632276, ST24039237, Flavone, 3',4',5,7-tetrahydroxy-6-methoxy-, A828884, C-19474, SR-01000777526, SR-01000777526-3, BRD-K05728858-001-01-7, Flavone, 3',4',5,7-tetrahydroxy-6-methoxy- (8CI), 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-chromen-4-one, 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-1-benzopyran-4-one, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one #, 2-[3,4-bis(oxidanyl)phenyl]-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy- (9CI)

ID: 580

InChIKey: FHIKZROVIDCMJA-UHFFFAOYSA-N
SMILES: CCCC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCCN(CC)CC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 65341
synonyms found at PubChem are:
Proadifen hydrochloride, 62-68-0, Proadifen HCl, Propyladiphenin, SKF-525A hydrochloride, SKF 525A, Proadifen (hydrochloride), SK&F 525-A, RP 5171, Proadifen hydrochloride [USAN], UNII-30624AA6X2, SKF 525-A, NSC 39690, U 5446, NSC 170997, SKF-525A, Hydrochloride, 5171 RP, 2-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride, 2-(Diethylamino)ethyl-2,2-diphenylvalerate hydrochloride, AI3-22677, 2'-Diethylaminoethyl 2,2-diphenylpentanoate hydrochloride, SKF-525A, 5171 R. P., Diethylaminoethanol ester of diphenylpropylacetic acid hydrochloride, 30624AA6X2, beta-Diethylaminoethyl diphenylpropylacetate hydrochloride, Proafiden hydrochloride, NCGC00094220-02, 2-Diethylaminoethyl alpha,alpha-diphenyl valerate hydrochloride, Pentanoic acid, 2,2-diphenyl-, 2-(N,N-diethylamino)ethyl ester, hydrochloride, Benzeneacetic acid, alpha-phenyl-alpha-propyl-, 2-(diethylamino)ethyl ester hydrochloride, DSSTox_CID_25792, DSSTox_RID_81133, DSSTox_GSID_45792, Proadifen hydrochloride (USAN), 2-(diethylamino)ethyl 2,2-diphenylpentanoate hydrochloride, Valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethyl ester, hydrochloride, WLN: 3XR&R&VO2N2&2 &GH, Benzeneacetic acid, alpha-phenyl-alpha-propyl-, 2-(diethylamino)ethyl ester, hydrochloride, Benzeneacetic acid, alpha-phenyl-alpha-propyl-, 2-(diethylamino)ethyl ester, monohydrochloride, SMR000326771, NSC39690, NSC170997, CAS-62-68-0, SR-01000075627, .beta.-Diethylaminoethyl diphenylpropylacetate hydrochloride, .beta.-Diethylaminoethyldiphenylpropylacetate hydrochloride, 2-(diethylamino)ethyl 2,2-diphenylpentanoate;hydrochloride, C23H31NO2.ClH, Benzeneacetic acid, 2-(diethylamino)ethyl ester hydrochloride, Valeric acid,2-diphenyl-, 2-(diethylamino)ethyl ester hydrochloride, Valeric acid,2-diphenyl-, 2-diethylaminoethyl ester, hydrochloride, Pentanoic acid,2-diphenyl, 2-(N,N-diethylamino)ethyl ester, hydrochloride, 2-(Diethylamino)ethyl 2,2-diphenylvalerate hydrochloride, Prestwick_124, 2-Diethylaminoethyl .alpha.,.alpha.-diphenyl valerate hydrochloride, Proadifen(hydrochloride), PROADIFENHYDROCHLORIDE, MLS000859910, MLS002222169, SCHEMBL122629, SPECTRUM1502084, SKF-525A HCl (Proadifen), CHEMBL347036, 302-33-0 (Parent), DTXSID1045792, CTK8G3113, KS-00001FBK, SK&F-525A, AOB5207, MolPort-002-218-942, [SKF-525A], HMS1570K18, HMS1921J04, Pharmakon1600-01502084, AC1L2331, HY-B1311, SK & F 525A, Tox21_111260, Tox21_500906, 2670AH, CCG-39663, MFCD00055151, NSC-39690, NSC758181, AKOS024463904, Tox21_111260_1, CS-4907, LP00906, MCULE-3342860303, NSC-170997, NSC-758181, RP-5171, NCGC00015799-06, NCGC00094220-01, NCGC00094220-03, NCGC00094220-04, NCGC00094220-05, NCGC00261591-01, AK161755, 5171 R. P, AX8149084, LS-161094, N,N-Diethylaminoethyl 2,2-diphenylvalerate, 4CH-023228, EU-0100906, FT-0603261, ST24049038, VU0244505-3, D05614, C-21528, Proadifen hydrochloride, analytical standard, >=95%, SR-01000075627-1, SR-01000075627-6, 2-diethylaminoethyl-2,2-diphenylvalerate hydrochloride, 2-diethylaminoethyl 2,2-diphenylpentanoate hydrochloride, Pentanoic acid,2,2-diphenyl-,diethylaminoethyl ester, hydrochloride, alpha-Phenyl-alpha-propylbenzeneacetic acid 2-(diethylamino)ethyl ester, Benzeneacetic acid, a-phenyl-a-propyl-, 2-(diethylamino)ethylester, hydrochloride (1:1), N,N- paragraph signthornOO degrees +/-OO>>u-2,2- paragraph signthorn+/-(1/2)IiEao yen, AKOS026750150

ID: 581

InChIKey: FHIVAFMUCKRCQO-UHFFFAOYSA-N
SMILES: CCOP(=S)(OCC)OC1=NC(=NC(=C1)C)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3017
synonyms found at PubChem are:
diazinon, Dimpylate, 333-41-5, Diazinone, Oleodiazinon, Neocidol, Ciazinon, Dassitox, Diazitol, Ektoband, Nedcidol, Spectracide, Antigal, Basudin, Bazuden, Dacutox, Dazzel, Diazide, Diazol, Exodin, Flytrol, Galesan, Nucidol, Sarolex, Dicid, Alfa-tox, Diazajet, Dimpylat, Garden Tox, Neocidol (oil), Bassadinon, Terminator, Compass, Disonex, Dizinon, Drawizon, Kayazinon, Kayazol, Meodinon, Dyzol, Nipsan, Diazinon ag 500, Knox-out, Delzinon, Dimpylatum, Dipofene, Dizictol, Neodinon, Optimizer, Bazudin, Dizinil, Srolex, Basudin 10 G, Geigy 24480, Basudin S, Knox Out 2FM, Bazudine, Diagran, Fezudin, Neotsidol, NCI-C08673, Kleen-Dok, AG-500, ENT 19,507, Isopropylmethylpyrimidyl diethyl thiophosphate, G-24480, KFM Blowfly Dressing, Compass (insecticide), Caswell No. 342, gardentox, Diziktol, Diaterr-fos, Dimpylatum [INN-Latin], O,O-Diethyl 2-isopropyl-4-methylpyrimidyl-6-thiophosphate, Cooper's Flystrike Powder, Dimpilato [INN-Spanish], NSC 8938, G 301, O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate, UNII-YUS1M1Q929, Dimpylate [INN], Diazinon [ANSI:BSI:ISO], CCRIS 204, Diethyl 4-(2-isopropyl-6-methylpyrimidinyl)phosphorothionate, O-2-Isopropyl-4-methylpyrimidyl-O,O-diethyl phosphorothioate, HSDB 303, Knox Out Yellow Jacket Contorl, O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) thionophosphate, CHEBI:34682, O,O-Diethyl O-6-methyl-2-isopropyl-4-pyrimidinyl phosphorothioate, OMS 469, EINECS 206-373-8, PT 265, EPA Pesticide Chemical Code 057801, Phosphorothioate, O,O-diethyl O-6-(2-isopropyl-4-methylpyrimidyl), BRN 0273790, Thiophosphate de O,O-diethyle et de O-2-isopropyl-4-methyl-6-pyrimidyle, 4-Pyrimidinol, 2-isopropyl-6-methyl-, O-ester with O,O-diethyl phosphorothioate, AI3-19507, Phosphorothioic acid, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester, YUS1M1Q929, Diethyl 2-isopropyl-4-methyl-6-pyrimidinyl phosphorothionate, NSC8938, Dimpylate (INN), O,O-Diethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiofosfaat, G 24480, Phosphorothioic acid, O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) ester, Diethyl 2-isopropyl-4-methyl-6-pyrimidyl thionophosphate, NCGC00091073-01, O,O-Diethyl 2-isopropyl-6-methyl-4-pyrimidinylphosphorothioate, DSSTox_CID_407, O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl)phosphorothioate, O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidyl)phosphorothioate, Thiophosphoric acid 2-isopropyl-4-methyl-6-pyrimidyl diethyl ester, O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate, O,O-diethyl O-[6-methyl-2-(1-methylethyl)pyrimidin-4-yl] thiophosphate, O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidinyl)-phosphorothioate, Phosphorothioic acid, O,O-diethyl O-(isopropylmethylpyrimidinyl) ester, O,O-Diaethyl-O-(2-isopropyl-4-methyl)-6-pyrimidyl-thionophosphat [German], O,O-Diaethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiophosphat [German], O,O-Diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl)phosphorothioate, O,O-Diethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiofosfaat [Dutch], O,O-Dietil-O-(2-isopropil-4-metil-pirimidin-6-il)-monotiofosfato [Italian], DSSTox_RID_75567, Phosphorothioic acid, O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] ester, Thiophosphate de O,O-diethyle et de O-2-isopropyl-4-methyl-6-pyrimidyle [French], DSSTox_GSID_20407, Diazinon, analytical standard, Q-200952, Dimpilato, O,O-Diaethyl-O-(2-isopropyl-4-methyl-pyrinidin-6-yl)-monothiophosphat, O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) phosphorothioate, diethoxy-(2-isopropyl-6-methyl-pyrimidin-4-yl)oxy-thioxo-$l^{5}-phosphane, CAS-333-41-5, Spertacide, Bazanon, Antlak, C12H21N2O3PS, Root guard, Fl ytrol, Diazinon solution, Di aterr-fos, Knox Out, Diethyl dimpylatum, diethoxy-(6-methyl-2-propan-2-ylpyrimidin-4-yl)oxy-sulfanylidene-?^{5}-phosphane, Dimpylate, INN, Basudin 5G, Spectracide 25EC, Agridin 60, Basudin 10G, 250MG - Diazinon, Spectrum_001777, Dimpylate [INN:BAN], New Z Diazinon (TN), SpecPlus_000344, AC1L1EZH, Spectrum2_001226, Spectrum3_000802, Spectrum4_000642, Spectrum5_001929, Optimizer Insecticide (TN), SCHEMBL17453, BSPBio_002263, KBioGR_000983, KBioSS_002258, 5-23-11-00187 (Beilstein Handbook Reference), MLS002207243, BIDD:ER0457, DivK1c_006440, SPBio_001072, CHEMBL388560, ZINC1309, DTXSID9020407, CTK1C2496, FHIVAFMUCKRCQO-UHFFFAOYSA-, KBio1_001384, KBio2_002257, KBio2_004825, KBio2_007393, KBio3_001763, FHIVAFMUCKRCQO-UHFFFAOYSA-N, HMS3264I04, Pharmakon1600-00330017, EBD29972, HY-B1113, NSC-8938, O,O-Diaethyl-O-(2-isopropyl-4-methyl)-6-pyrimidyl-thionophosphat, o,o-diethyl o-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate, Tox21_111077, Tox21_201409, Tox21_300730, ACM333415, BDBM50005409, CCG-39143, ENT 19507, NSC755893, O,O-Diaethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiophosphat, O,O-Dietil-O-(2-isopropil-4-metil-pirimidin-6-il)-monotiofosfato, Diazinon 10 microg/mL in Cyclohexane, AKOS025311513, Tox21_111077_1, CS-4712, Diazinon 10 microg/mL in Acetonitrile, Diazinon 100 microg/mL in Cyclohexane, LS-1209, NSC-755893, PST0000180, Diazinon 100 microg/mL in Acetonitrile, Phosphorothioic acid O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] ester, NCGC00091073-02, NCGC00091073-03, NCGC00091073-04, NCGC00091073-05, NCGC00091073-06, NCGC00091073-07, NCGC00254636-01, NCGC00258960-01, AN-44362, BC225665, CC-26452, SMR000777921, ZB000307, SBI-0052498.P002, DB-048387, Diazinon, PESTANAL(R), analytical standard, FT-0603088, C14324, D07856, AB00053004_04, 333D415, C-18970, SR-01000872734, SR-01000872734-1, BRD-K60567437-001-04-5, Diazinon, certified reference material, TraceCERT(R), 4-Pyrimidinol, O-ester with O,O-diethyl phosphorothioate, WLN: T6N CNJ BY1 & 1 DOPS & O2 & O2 F1, Diethyl 2-isopropyl-4-met hyl-6-pyrimidyl thionophosphate, O, O-Diethyl 2-isopropyl-4-methylpyrimidyl-6-thiophosphate, O,O-Diethyl-O-(2-isopropyl-4-methylpyrimidyl)thiophosphate, diethyl 2-isopropyl-6-methyl-4-pyrimidinyl phosphorothionate, O,O-diethyl O-2-isopropyl-4-methyl-6-pyrimidyl thiophosphate, o,o-Dietil-o-(2-isopropil-4-metil-pirimidin-il)-monotiofosato, Phosphorothioate,O-diethyl O-6-(2-isopropyl-4-methylpyrimidyl), Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate, O,O-Diethyl O-(2-isopropyl-6-methyl-4-primidinyl)phosphorothioate, O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) thiophosphate, O,O-Diethyl o-(2-isopropyl-6-methyl-4-pyrimidinyl) thiophosphate #, O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate, O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidyl) thiophosphate, diethoxy-(6-methyl-2-propan-2-ylpyrimidin-4-yl)oxy-sulfanylidenephosphorane, Diethoxy-[(2-isopropyl-6-methyl-4-pyrimidinyl)oxy]-thioxophosphorane, O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidinyl) thiophosphoric acid, O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl), phosphorothioa te, O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl), phosphorothioate, O,O-Diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosophorothioate, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosphorothioate, O,O-diethyl O-[6-methyl-2-(propan-2-yl)pyrimidin-4-yl] phosphorothioate, o,o-Diethyl-O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl)phosophorothioate, Phosphorothioic acid, O,O-diethyl 2-isopropyl-6-methyl-4-pyrimidinyl ester, Phosphorothioic acid,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) ester, Diazinon solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, ethyl 6-methyl-2-(propan-2-yl)pyrimidin-4-yl ethoxy(sulfanylidene)phosphonite, Phosphorothioc Acid O,O-Diethyl O-[6-Methyl-2-(1-methylethyl)-4-pyrimidinyl] Ester, Phosphorothioic acid O,O-diethyl O-[6-methyl- 2-(1-methylethyl)-4-pyrimidinyl] ester, Phosphorothioic acid, O,O-diethyl {O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl]} ester, PHOSPHOROTHIOIC ACID,O-DIETHYL O-[6-METHYL-2-(1-METHYLETHYL)-4-PYRIMIDINYL] ESTER, 27936-40-9, 30583-38-1, 65863-03-8, InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3, O,O-Diethyl O-2-isopropyl-4-methyl-6-pyrimidyl thiophosphate; O,O-Diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosophorothioate

ID: 582

InChIKey: FHYWNBUFNGHNCP-UHFFFAOYSA-N
SMILES: CC1=CC=CC(=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)C.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957685
synonyms found at PubChem are:
SKF 83959 hydrobromide, SKF-83959 hydrobromide, 67287-95-0, CHEBI:63996, 6-chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, 80751-85-5, CHEMBL520992, 6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, SR-01000076126, EU-0101067, 6-CHLORO-2,3,4,5-TETRAHYDRO-3-METHYL-1-(3-METHYLPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE, MLS002153381, DTXSID9042629, SCHEMBL12610614, CTK8G3112, MolPort-003-959-525, Tox21_501067, BN0488, MFCD03792727, AKOS024456929, API0007826, CCG-222371, LP01067, SKF-83,959, NCGC00094346-01, NCGC00261752-01, 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide, 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide (1:1), LS-27995, SMR001230770, S 2816, SKF-83959 hydrobromide, >=98% (HPLC), solid, SR-01000076126-2, SR-01000076126-3, 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-1H-3-benzazepine-7,8-diol, 6-chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide, N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide

ID: 583

InChIKey: FIKFLLIUPUVONI-UHFFFAOYSA-N
SMILES: C1CN(CCC12CNC(=O)O2)CCC3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 68626
synonyms found at PubChem are:
Fenspiride hydrochloride, Fenspiride HCl, 5053-08-7, Decaspiride, Fluiden, Pneumorel, Fenspiride (Hydrochloride), Espiran, Tegencia hydrochloride, Viarespan hydrochloride, NDR-5998A, NAT-333, JP 428, UNII-832NBX878V, Fenspiride hydrochloride [USAN], 832NBX878V, 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride, EINECS 225-752-9, NCGC00093898-02, DSSTox_CID_25770, DSSTox_RID_81112, DSSTox_GSID_45770, Fenspiride hydrochloride (USAN), 8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride, Phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2-hydrochloride, 8-Phenethyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one monohydrochloride, 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-phenethyl-, monohydrochloride, 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride, 8-N-Fenetil-1-oxa-2-oxo-3,8-diazaspiro-(4,5)-decano cloridrato [Italian], Chlorhydrate de phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 [French], 1-Oxa-3,8-diazaspiro(4,5)decan-2-one, 8-(2-phenylethyl)-, monohydrochloride, 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(2-phenylethyl)-, monohydrochloride, CAS-5053-08-7, SR-01000075878, Decaspir, Erespal, Tegencia, zlchem 11, Prestwick_218, D0V8KI, AC1L2A4D, AC1Q3ES9, MLS001056735, C15H20N2O2.ClH, SCHEMBL613462, SPECTRUM1501021, CHEMBL1256849, DTXSID3045770, CTK4J2764, NDR 5998A, KSP-193, NAT 333, ZLA0013, MolPort-003-666-347, HMS1568L07, HMS1921D09, Pharmakon1600-01501021, BCP13398, HY-A0027, Tox21_111230, Tox21_500496, 2410AH, CCG-39014, MFCD00133315, NSC757825, s4090, 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride(1:1), AKOS027326501, Tox21_111230_1, API0002692, CS-0764, EBD3062809, LP00496, NSC-757825, NCGC00015438-07, NCGC00093898-01, NCGC00093898-03, NCGC00093898-04, NCGC00093898-05, NCGC00261181-01, LS-98946, SMR000326706, EU-0100496, D04163, F 6145, W-5078, 5053-08-7, 5053-06-5(free base), SR-01000075878-1, SR-01000075878-6, Fenspiride hydrochloride, analytical standard, for drug analysis, 8-N-Fenetil-1-oxa-2-oxo-3,8-diazaspiro-(4,5)-decano cloridrato, 8-phenethyl-4-oxa-2,8-diazaspiro[4.5]decan-3-one hydrochloride, Chlorhydrate de phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2, 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one,hydrochloride, 1-Oxa-3,8-diazaspiro[4.5]decan-2-one,8-(2-phenylethyl)-, hydrochloride (1:1), 2-OXAZOLIDINONE-5-SPIRO-4'-[N-(2-PHENYLETHYL)PIPERIDINE] HYDROCHLORIDE, SCHEMBL17006239, AKOS026749884

ID: 584

InChIKey: FIMUDWRKPYKTJN-UHFFFAOYSA-N
SMILES: C1C[N+]2=CC=CC=C2N1.[Br-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 44887158
synonyms found at PubChem are:
2,3-Dihydro-imidazo[1,2-a]pyridine Hydrobromide, AKOS027447857

ID: 585

InChIKey: FIQGIOAELHTLHM-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NCCN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5697
synonyms found at PubChem are:
Xanthine amine congener, Papaxac, 96865-92-8, XAC, [3H]xanthine amine congener, [3H]XAC, CHEMBL273094, 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine, N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide, n-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1h-purin-8-yl)phenoxy]acetamide, Xanthine amine congener xac, 8-[4-[[[[(2-Aminoethyl)amino]carbonyl]methyl]oxy]phenyl]-1,3-dipropylxanthine, N-(2-aminoethyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide, Lopac-X-103, AC1L1KXN, AC1Q5PIP, D09HUM, D0H9BP, 8-(4-(((2-(4-Aminophenylacetylamino)ethyl)carbonyl)methyl)oxy)phenyl-1,3-dipropylxanthine, Lopac0_001279, GTPL404, GTPL432, SCHEMBL1000686, CTK8G3788, DTXSID10242595, FIQGIOAELHTLHM-UHFFFAOYSA-N, ZINC9210767, BDBM50207816, PDSP1_000319, PDSP1_000445, PDSP2_000317, PDSP2_000443, CCG-205352, LP01279, NCGC00016097-01, NCGC00016097-02, NCGC00016097-03, NCGC00016097-04, NCGC00094514-01, NCGC00094514-02, Xanthine amine congener, >=96% (HPLC), EU-0101279, X-103, L000963, SR-01000075243, SR-01000075243-1, 3,7-diethyl-9-(4-(N-2-aminoethylcarboxamidomethoxy))phenylxanthine, Xanthine, 8-[4-[(2-aminoethyl)aminocarbonyl]methoxyphenyl]-1,3-dipropyl, 8-[4-[[[[(2-Aminoethyl)amino] carbonyl]methyl]oxy]phenyl]-1,3-dipropylxanthine, XAC(8-[4-[[[[(2-Aminoethyl)amino] carbonyl]methyl]oxy]phenyl]-1,3-dipropylxanthine, Acetamide, N-(2-aminoethyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)-, N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide, N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide (xanthine amine congenere, XAC), N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide(XAC), N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide, N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide hydrochloride, N-(2-Aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy]acetamide #

ID: 586

InChIKey: FIVHOHCAXWQPGC-UHFFFAOYSA-N
SMILES: CN(C)CCOC(=O)COC1=CC=C(C=C1)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 19379
synonyms found at PubChem are:
Meclofenoxate hydrochloride, 3685-84-5, Centrophenoxine hydrochloride, Meclofenoxate HCl, Lucidril, Cerutil, Atsefen, Helfergin, Marucotol, Acefen, Brenal, Centrophenoxine, Centrofenoxin, Amipolen, Cellative, Proserout, Lutiaron, Meclophenoxate hydrochloride, Methoxynal, 235 Anp hydrochloride, Centrophenoxine (VAN), 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride, UNII-5BK3070BDY, Meclofenoxate (hydrochloride), Lucidryl hydrochloride, Dimethylaminoethyl p-chlorophenoxyacetate hydrochloride, NSC 4268, EINECS 222-975-3, 2-(dimethylamino)ethyl (4-chlorophenoxy)acetate hydrochloride, Chlorowodorki centrofenoksyna [Polish], NSC 113619, Dimethylaminoethyl 4-chlorophenoxyacetate hydrochloride, 5BK3070BDY, p-Chlorphenoxyessigsaeure-beta-dimethylaminoaethylesters [German], Dimethylaminoethyl ester of p-chlorophenoxyacetic acid hydrochloride, (p-Chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester hydrochloride, C12H16ClNO3, DSSTox_CID_25141, DSSTox_RID_80699, DSSTox_GSID_45141, 2-(Dimethylamino)ethyl (p-chlorophenoxy)acetate hydrochloride, 4-chlorophenoxy-acetic acid 2-(dimethylamino)ethyl ester hydrochloride, WLN: GR DO1VO2N1&1 &GH, 2-(4-Chlorophenoxy)acetic Acid 2-(Dimethylamino)ethyl Ester Hydrochloride, ACETIC ACID, (p-CHLOROPHENOXY)-, 2-DIMETHYLAMINOETHYL ESTER, HYDROCHLORIDE, SR-01000075788, NCGC00015279-02, CAS-3685-84-5, Acetic acid, 2-(dimethylamino)ethyl ester hydrochloride, Chlorowodorki centrofenoksyna, Methocynal, 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate;hydrochloride, (Dimethylamino)ethyl ester of (p-chlorophenoxy)acetic acid hydrochloride, Meclofenoxate hydrochloride [JAN], Centrophenoxine HCl, Lucidril (TN), Prestwick_978, PubChem23391, AC1Q3BLJ, Meclofenoxat hydrochloride, Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride, C12H17Cl2NO3, MLS002153989, SCHEMBL218322, SPECTRUM1503226, AC1L2E01, p-Chlorphenoxyessigsaeure-beta-dimethylaminoaethylesters, CHEMBL1256131, DTXSID8045141, CTK8F3645, NSC4268, HMS1570I08, HMS1922K09, Pharmakon1600-01503226, Centrophenoxine hydrochloride, 99%, BCP21567, Meclofenoxate (Centrophenoxine) HCl, Meclofenoxate hydrochloride (JP17), NSC-4268, Tox21_110123, Tox21_302398, Tox21_500250, CCG-39961, NSC113619, NSC758420, s4280, AKOS008968424, Tox21_110123_1, AC-1680, AN-6971, CS-2216, KS-1179, LP00250, MCULE-1367655174, NSC-113619, NSC-758420, NCGC00015279-08, NCGC00093712-01, NCGC00093712-02, NCGC00093712-03, NCGC00093712-04, NCGC00180932-01, NCGC00256151-01, NCGC00260935-01, BC213252, H907, HY-17555, LS-11345, SC-15165, SMR001233323, AB0013350, EU-0100250, FT-0603646, M2460, EN300-35717, C 8773, D02243, K-8196, I01-1863, SR-01000075788-1, SR-01000075788-5, SR-01000075788-6, W-106584, Dimethylaminoethyl 4-Clorophenoxyacetate Hydrochloride, Z57281900, 2-dimethylaminoethyl 2-(4-chlorophenoxy)acetate hydrochloride, Meclofenoxate Hydrochloride 1.0 mg/ml in Acetonitrile (as free base), Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride (9CI), 1334-20-9, AKOS026750100

ID: 587

InChIKey: FIVPIPIDMRVLAY-RBJBARPLSA-N
SMILES: CN1C(=O)[C@]23CC4=CC=C[C@@H]([C@H]4N2C(=O)[C@]1(SS3)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6223
synonyms found at PubChem are:
gliotoxin, 67-99-2, Aspergillin, UNII-5L648PH06K, CCRIS 4025, Gliotoxin from Gliocladium fimbriatum, NSC 102866, BRN 0050675, AI3-62383, CHEBI:5385, CHEMBL331627, S.N. 12870, 5L648PH06K, Gliotoxin, Gladiocladium fimbriatum, 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione, 2,3,5a,6-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-, Gliotoxins, (3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione, 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione, 2,3,5a,6-hydroxy-3- (hydroxymethyl)-2-methyl-, (3R-(3-alpha,5a-beta,6-beta,10a-alpha))-, 2,3,5a,6-Tetrahydro-6-hydroxy-3(hyroxymethyl)-2-methyl-10H-3a,10a-epidithio-pyrazinol[1,2alpha]indole-1,4-dione, NSC102866, D0N1XD, SCHEMBL54420, BSPBio_001237, 4-27-00-08902 (Beilstein Handbook Reference), AC1L1M29, MolPort-008-268-260, ZX-AFC000329, HMS1792M19, HMS1990M19, HMS3403M19, PI129, ZINC3875454, BDBM50134315, CCG-35318, CCG-36058, MFCD00058534, AKOS024457211, QTL1_000040, NCGC00163466-01, NCGC00163466-02, LS-63988, C10595, C-46242, SR-05000002340, SR-05000002340-2, Gliotoxin solution, 100 mug/mL in acetonitrile, analytical standard, (3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione, 6-Hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione, 7-hydroxy-11-hydroxymethyl-12-methyl-14,15-dithia-9,12-diazatetracyclo[9.2.2.01,9.03,8]pentadeca-3,5-diene-10,13-dione

ID: 588

InChIKey: FJDDSMSDZHURBJ-UHFFFAOYSA-N
SMILES: CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 115348
synonyms found at PubChem are:
2-Iodomelatonin, 93515-00-5, 2-iodo-melatonin, n-[2-(2-iodo-5-methoxy-1h-indol-3-yl)ethyl]acetamide, 2-I-MLT, CHEMBL289233, N-(2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl)acetamide, acetamide,n-[2-(2-iodo-5-methoxy-1h-indol-3-yl)ethyl]-, Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-, (3beta)-, Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-, SR-01000075935, Melatonin,2-Iodo, ML2, Tocris-0737, Lopac-I-1899, D08VEJ, D0H6YF, AC1L3GZ8, AC1Q5P6Z, Lopac0_000610, SCHEMBL163451, GTPL1343, BDBM29611, CTK8F4316, DTXSID30239462, CHEBI:109558, FJDDSMSDZHURBJ-UHFFFAOYSA-N, MolPort-003-983-480, HMS3266P03, ZINC2516056, BN0011, N-acetyl-2-iodo-5-methoxytriptamine, N-Acetyl-2-iodo-5-methoxytryptamine, PDSP1_001785, PDSP2_001768, AKOS024458623, CCG-204699, DB08190, LS-9790, NCGC00015552-01, NCGC00015552-02, NCGC00015552-03, NCGC00024758-01, NCGC00024758-02, KB-270628, B6428, EU-0100610, FT-0737435, A15343, I 1899, L000060, SR-01000075935-1, SR-01000075935-3, BRD-K25649279-001-01-2, N-[2-(2-IODO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE

ID: 589

InChIKey: FJIKEFFDENQLIH-UHFFFAOYSA-M
SMILES: CC1=C2C=C(C(=CC2=CC3=[N+]1C=CC4=CC(=C(C=C43)OC)OC)OC)OC.O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6419900
synonyms found at PubChem are:
Coralyne chloride hydrate, 1031265-39-0, Prestwick_129, AC1O4WG2, MLS002153808, SCHEMBL4022544, CHEMBL1444353, FJIKEFFDENQLIH-UHFFFAOYSA-M, MolPort-000-698-746, HMS1569G04, HMS2096G04, AKOS024374919, NCGC00017109-01, NCGC00017109-02, SMR001233180, CAS-38989-38-7, ST51014955, 2,3,10,11-tetramethoxy-8-methylisoquinolino[2,1-b]isoquinolin-7-ium chloride hydrate, 2,3,10,11-tetramethoxy-8-methylisoquinolino[2,1-b]isoquinoline, oxamethane, ch loride

ID: 590

InChIKey: FJLBFSROUSIWMA-UHFFFAOYSA-N
SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4174
synonyms found at PubChem are:
metyrapone, 54-36-4, Metopirone, 2-Methyl-1,2-di-3-pyridyl-1-propanone, Methopyrapone, Metopiron, Methapyrapone, Methopirapone, Methopyrinine, Methopyrone, Metyrapon, Methbipyranone, Metopyrone, Mepyrapone, Metroprione, Metapirone, Metapyron, Metirapona, Metyraponum, Su 4885, Metapyrone, 1-Propanone, 2-methyl-1,2-di-3-pyridinyl-, Metyraponum [INN-Latin], Metirapona [INN-Spanish], 2-Methyl-1,2-di-3-pyridinyl-1-propanone, 2-methyl-1,2-dipyridin-3-ylpropan-1-one, UNII-ZS9KD92H6V, 2-Methyl-1,2-bis(3-pyridyl)-1-propanone, NSC 25265, 1,2-Di-3-pyridyl-2-methyl-1-propanone, C14H14N2O, HSDB 2500, 1-Propanone, 2-methyl-1,2-di-3-pyridyl-, Metyrapone [USAN:INN:BAN:JAN], METOPIRONE (TN), Su-4885, EINECS 200-206-2, CHEMBL934, ZS9KD92H6V, 1-Propanone, 1,2-di-3-pyridyl-2-methyl-, 2-methyl-1,2-dipyridin-3-yl-propan-1-one, CHEBI:44241, 2-methyl-1,2-bis(pyridin-3-yl)propan-1-one, FJLBFSROUSIWMA-UHFFFAOYSA-N, CAS-54-36-4, NCGC00016242-01, DSSTox_CID_3314, DSSTox_RID_76971, DSSTox_GSID_23314, MYT, SMR000059134, Metyrapone [USAN:USP:INN:BAN:JAN], PubChem16052, AC1L1HKV, AC1Q1LHX, Metyrapone Alliance Brand, Metyrapone Novartis Brand, Prestwick0_000904, Prestwick1_000904, Prestwick2_000904, Prestwick3_000904, D0Q9JT, Alliance Brand of Metyrapone, Novartis Brand of Metyrapone, BIDD:PXR0082, BSPBio_000748, MLS001066377, MLS001335881, MLS001335882, SCHEMBL637432, SPBio_002947, 1-Propanone,2-di-3-pyridyl-, BPBio1_000824, GTPL5224, Metyrapone (JP15/USP/INN), Metyrapone (JP17/USP/INN), ZINC1728, DTXSID1023314, 1-Propanone,2-di-3-pyridinyl-, CTK8B5187, KS-00001FBF, MolPort-001-794-644, HMS1570F10, HMS2094I07, HMS2097F10, HMS2235E16, HMS3259O05, HMS3371B16, HMS3714F10, Pharmakon1600-01506014, BCP19099, EX-A1403, HY-B1232, NSC25265, Tox21_110323, ANW-47874, BDBM50028166, BG0427, MFCD00006397, NSC-25265, NSC760076, AKOS015919707, Metyrapone, >=98% (HPLC), solid, Tox21_110323_1, API0003315, CCG-213598, CS-4879, DB01011, MCULE-7018205003, NC00462, NSC-760076, NCGC00016242-02, NCGC00016242-03, NCGC00016242-05, NCGC00161837-01, AJ-08075, AN-41656, BR-51541, CC-30940, CPD000059134, SAM002297829, SC-49180, ZB000400, 2-methyl-1,2-di(3-pyridyl)propan-1-one, 2-methyl-1,2-bis(3-pyridyl)propan-1-one, AX8140081, LS-123097, TC-136619, 2-methyl-1,2-bis(3-pyridinyl)-1-propanone, AB00513955, B7347, EU-0009322, FT-0603230, ST24028079, ST51006925, W6860, 2-methyl-1,2-di(pyridin-3-yl)propan-1-one, 2-Methyl-1,2-di(3-pyridinyl)-1-propanone #, C07205, D00410, S-6399, 2-Methyl-1,2-di-3-pyridyl-1-propanone, 96%, AB00513955_07, 054M364, A830124, C-12887, SR-01000765398, SR-01000765398-2, BRD-K46862739-001-03-6, I14-92873, Metyrapone, United States Pharmacopeia (USP) Reference Standard, 37245-80-0

ID: 591

InChIKey: FKJIJBSJQSMPTI-CAOXKPNISA-M
SMILES: C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1(C(=O)C[C@H]3[C@H]2C(=O)C[C@H]4[C@@]3(CCC(=O)C4)C)C.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 13338976
synonyms found at PubChem are:
Sodium dehydrocholate, 145-41-5, DEHYDROCHOLATE SODIUM, Dehydrocholate (sodium), Biliron, Carachol, Dehydrocholic acid sodium salt, UNII-W4193719XR, Biliton, Dycholium, Suprachol, Dilabil sodium, Decholin Sodium, Decholin sodium salt, W4193719XR, Natriumdehydrocholat [German], Dehydrocholic acid, sodium salt, Sodium 3,7,12-triketocholanate, Natrii dehydrocholas [INN-Latin], Dehidrocolato sodico [INN-Spanish], EINECS 205-652-1, 81-23-2 (Parent), Dehydrocholate de sodium [INN-French], Natriumdehydrocholat, Sodium 3,7,12-trioxo-5-beta-cholanate, Dehidrocolato sodico, Natrii dehydrocholas, Triceto 3-7-12 cholanate de Na [French], Sodium 3,7,12-trioxo-5beta-cholan-24-oate, Sodium 3,7,12-trioxo-5-beta-cholan-24-oate, Dehydrocholate de sodium, Dehydrocholate sodium [USP], 5-beta-Cholan-24-oic acid, 3,7,12-trioxo-, monosodium salt, Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5-beta)-, Triceto 3-7-12 cholanate de Na, 3,7,12-Trioxo-5beta-cholanic acid sodium salt, E yenCamicro Ea AAENI, Dehydrocholic acid sodium, 5-beta-Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, Sodium dehydrocholate [INN], C24H33NaO5, Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5beta)-, SCHEMBL164693, CHEMBL2106184, FKJIJBSJQSMPTI-CAOXKPNISA-M, MolPort-003-929-781, HY-B0998, AKOS025311010, CS-4492, 3,7,12-EyNo-5|A-micro IeEa AAENI, O606, D0043, J-008101, I14-101286, 1510-17-4, sodium (4R)-4-[(1S,2S,7S,10R,11S,14R,15R)-2,15-dimethyl-5,9,16-trioxotetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanoate, sodium (4R)-4-[(1S,2S,7S,10R,11S,14R,15R)-2,15-dimethyl-5,9,16-trioxotetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]pentanoate

ID: 592

InChIKey: FKUVCCNCUAFKAH-UTONKHPSSA-N
SMILES: CCCN(CCC)[C@@H]1CCC2=C(C=CC(=C2C1)O)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957726
synonyms found at PubChem are:
R(+)-UH-301 hydrochloride, UNII-O8ROD11G06, O8ROD11G06, R(+)-5-Fluoro-8-Hydroxy-DPAT hydrochloride, SR-01000075591, 127126-18-5, CHEMBL1256996, (R)-5-Fluoro-8-hydroxy-2-(dipropylamino)tetralin hydrochloride, 5-Fluoro-8-hydroxy-2-(dipropylamino)tetralin hydrochloride, (R)-, (R)-(+)-5-Fluoro-8-hydroxy-2-(dipropylamino)tetralin hydrochloride, R(+)-UH-301 hydrochloride, solid, 1-Naphthalenol, 7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydro-, hydrochloride (1:1), (7R)-, NCGC00094487-01, 127126-20-9, EU-0101246, U-109, J-005466, SR-01000075591-1, SR-01000075591-2, R(+)-5-Fluoro-8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalene hydrochloride

ID: 593

InChIKey: FLEXCYTURSFUNC-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C3=C(O2)C4=C(C=C(C=C4)OC)OC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 624785
synonyms found at PubChem are:
Dehydrovariabilin, Anhydrovariabilin, 3,9-Dimethoxypterocarpene, 1433-08-5, FLEXCYTURSFUNC-UHFFFAOYSA-N, KBio2_000462, AC1LDQRU, Spectrum_000062, 3,9-Dimethoxypterocarpen, Spectrum2_000058, Spectrum3_000259, Spectrum4_001626, Spectrum5_000411, BSPBio_001678, KBioGR_002031, KBioSS_000462, SPECTRUM210658, 3,9-Dimethoxy-6H-benzofuro[3,2-c][1]benzopyran, SPBio_000215, 6H-Benzofuro[3,2-c][1]benzopyran, 3,9-dimethoxy-, CHEMBL1520512, SCHEMBL13657398, KBio2_003030, KBio2_005598, KBio3_001178, ZINC3473153, CCG-38365, LMPK12070150, 3,9-Dimethoxypterocarp-6a(11a)-en, AKOS000277249, SDCCGMLS-0066548.P001, NCGC00095524-01, NCGC00095524-02, NCGC00179096-01, 3,9-dimethoxy-6H-benzofuro[3,2-c]chromene, 3,9-Dimethoxy-6H-[1]benzofuro[3,2-c]chromene, SR-05000002528, 3,9-Dimethoxy-6H-[1]benzofuro[3,2-c]chromene #, SR-05000002528-1, NCGC00095524-04!3,9-dimethoxy-6H-[1]benzofuro[3,2-c]chromene

ID: 594

InChIKey: FLGYCSPPJQJZCH-LCYFTJDESA-N
SMILES: C1=CC=C2C=C(C=CC2=C1)NCC(=O)NN/C=C\3/C=C(C(=C(C3=O)Br)O)Br

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"H Senderowitz" "BB Stauffer" "BR Imhoff" "NA McCarty" "N Khazanov" "DT Infield" "G Cui"

CID is 11260414
synonyms found at PubChem are:
GlyH-101, 328541-79-3, CFTR Inhibitor II, (Naphthalen-2-ylamino)-acetic acid (3,5-dibromo-2,4,-dihydroxy-benzylidene)-hydrazide, GlyH - 101, MolPort-006-416-077, N-(2-naphthalenyl)-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide, N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide, 3698AH, AKOS025148694, ZINC100478919, CS-2098, BC600597, HY-18336, KB-02594, KB-52296, (Naphthalen-2-ylamino)-acetic acid (3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide, (Naphthalen-2-ylamino)acetic acid (3,5-dibromo-2,4,-dihydroxybenzylidene)hydrazide

ID: 595

InChIKey: FLGYCSPPJQJZCH-UHFFFAOYSA-N
SMILES: C1=CC=C2C=C(C=CC2=C1)NCC(=O)NNC=C3C=C(C(=C(C3=O)Br)O)Br

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"H Senderowitz" "BB Stauffer" "BR Imhoff" "NA McCarty" "N Khazanov" "DT Infield" "G Cui"

CID is 53397780
synonyms found at PubChem are:
GlyH-101, CTK8E9894, AGN-PC-005HH0, 328541-79-3, CFTR Inhibitor II, GlyH-101, CFTR Inhibitor II, D0S1FV, GTPL4202, N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide, AOB87126, BCP10956, KS-00001DB4, ZINC22115071, AKOS026750493, N'-[(3,5-dibromo-4-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-2-(naphthalen-2-ylamino)acetohydrazide

ID: 596

InChIKey: FLGYCSPPJQJZCH-UKTHLTGXSA-N
SMILES: C1=CC=C2C=C(C=CC2=C1)NCC(=O)NN/C=C/3\C=C(C(=C(C3=O)Br)O)Br

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"H Senderowitz" "BB Stauffer" "BR Imhoff" "NA McCarty" "N Khazanov" "DT Infield" "G Cui"

CID is 16760366
synonyms found at PubChem are:
GlyH-101, GlyH 101, CFTR Inhibitor II, GlyH-101, CHEMBL1221576, 328541-79-3, N-(2-Naphthalenyl)-((3,5-dibromo-2,4-dihydroxyphenyl)methylene)glycine hydrazide, SCHEMBL12648530, BDBM50324733, AKOS032947331, ZINC100478920, S8094, EC-000.1907, J-018908, N''-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide, N'-[(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide, N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide

ID: 597

InChIKey: FLMOMVBGUCEQEW-UHFFFAOYSA-L
SMILES: C[N+](C)(C)CCCCCC[N+](C)(C)C.O.O.[Br-].[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6419940
synonyms found at PubChem are:
UNII-E010109G6B, Hexamethonium dibromide dihydrate, E010109G6B, Hexamethonium bromide dihydrate, Prestwick_259, AC1O4WGM, CHEMBL1405927, HMS1568G17, HMS2095G17, HMS3712G17, CCG-220038, 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide, hydrate (1:2:2), CAS-55-97-0, NCGC00017011-01, 5187-74-6, hexamethylene di(trimethylammonium) dibromide dihydrate, trimethyl-[6-(trimethylazaniumyl)hexyl]azanium dibromide dihydrate

ID: 598

InChIKey: FLMPHRLJTGZEDL-UHFFFAOYSA-N
SMILES: C1=CC=[NH0+]2C3C=CC=CC=3C(O)=CC2=C1.[ClH0-]

biological descriptors:

CFTR relevance: inactive analogue

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"C Rogier" "L Dannhoffer" "H DeJonge" "Y Mettey" "S Noël" "M Wilke" "F Becq" "PO Strale"

CID is 11776085
synonyms found at PubChem are:
CHEMBL171993, 71711-67-6, DTXSID40472368, NSC368298, NSC-368298, benzo[c]quinolizin-11-ium-6-ol,chloride

ID: 599

InChIKey: FLMSQRUGSHIKCT-DDZQJACLSA-N
SMILES: C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2[C@@H](C[C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6437
synonyms found at PubChem are:
Sarmentogenin, 11-alpha-Hydroxydigitoxigenin, UNII-EX5655UIRZ, EX5655UIRZ, CHEBI:37665, 3beta,11alpha,14-Trihydroxy-5beta-card-20(22)-enolide, 76-28-8, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,11-alpha,14-TRIHYDROXY-, Card-20(22)-enolide, 3,11,14-trihydroxy-, (3beta,5beta,11alpha)-, AC1L1MJ6, SCHEMBL1230965, CHEMBL1075814, LS-52504, 3-[(3S,5R,8R,9S,10S,11R,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

ID: 600

InChIKey: FLOSMHQXBMRNHR-UHFFFAOYSA-N
SMILES: CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4100
synonyms found at PubChem are:
methazolamide, 554-57-4, Methenamide, Neptazane, Neptazaneat, Metazolamida, Metazolamide, Methazolamidum, Naptazane, Metazolamide [DCIT], Metazolamida [INN-Spanish], Methazolamidum [INN-Latin], UNII-W733B0S9SD, C5H8N4O3S2, CHEBI:6822, HSDB 3269, EINECS 209-066-7, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide, BRN 0232387, UNII-DA43GW06P1, MLS000028532, CHEMBL288100, DA43GW06P1, W733B0S9SD, Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-, Acetamide, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-, NCGC00016508-01, CAS-554-57-4, SMR000058287, 2-Acetylimino-3-methyl-delta(sup 4)-1,3,4-thiadiazoline-5-sulfonamide, 5-Acetylimino-4-methyl-delta(sup 2)-1,3,4-thiadiazoline-2-sulfonamide, N-(4-Methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)acetamide, N-(3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene)acetamide, Acetamide, N-(4-methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)-, N-[(2E)-5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, SR-05000001844, Methazolamid, Methazolamide [INN:BAN:JAN], 2-Acetylimino-3-methyl-.delta.(4)-1,3,4-thiadiazoline-5-sulfonamide, 3-methyl-2-(2-oxo-1-azapropylidene)-1,3,4-thiadiazoline-5-sulfonamide, 5-Acetylimino-4-methyl-.delta.(2)-1,3,4-thiadiazoline-2-sulfonamide, N-(4-Methyl-2-sulfamoyl-.delta.2-1,3,4-thiadiazolin-5-ylidene)acetamide, N-(5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide #, Acetamide, N-(4-methyl-2-sulfamoyl-.delta.2-1,3,4-thiadiazolin-5-ylidene)-, Neptazane (TN), Methazolamide,(S), Methazolamide [USP:INN:BAN:JAN], Methazolamide, MZA, Prestwick_1007, Methazolamide (MZA), Methazolamide, (Z)-, Spectrum_001615, Opera_ID_717, AC1L1HEV, CHEMBL19, MZA3, Prestwick0_000802, Prestwick1_000802, Prestwick2_000802, Prestwick3_000802, Spectrum2_001543, Spectrum3_001914, Spectrum4_000190, Spectrum5_001006, DSSTox_CID_3281, D0C2II, cid_4100, DSSTox_RID_76956, DSSTox_GSID_23281, Oprea1_161738, SCHEMBL24686, SCHEMBL24687, BSPBio_000663, BSPBio_003508, KBioGR_000739, KBioSS_002095, 4-27-00-08221 (Beilstein Handbook Reference), MLS001146905, DivK1c_000582, SPECTRUM1503252, SPBio_001386, SPBio_002584, AC1Q40D8, AC1Q40D9, BPBio1_000731, GTPL6828, Methazolamide (JAN/USP/INN), CHEMBL1335656, DTXSID1023281, SCHEMBL13825893, BDBM10881, CHEBI:94513, CTK8G0825, HMS501N04, KBio1_000582, KBio2_002095, KBio2_004663, KBio2_007231, KBio3_003013, FLOSMHQXBMRNHR-DAXSKMNVSA-N, FLOSMHQXBMRNHR-QPJJXVBHSA-N, FLOSMHQXBMRNHR-UHFFFAOYSA-N, Methazolamide, >=98% (HPLC), MolPort-001-791-152, MolPort-019-998-640, NINDS_000582, HMS1570B05, HMS1922M19, HMS2093A05, HMS2097B05, HMS2234L03, HMS3259H05, HMS3372G12, HMS3652E21, HMS3714B05, Pharmakon1600-01503252, EBD27355, HY-B0553, KS-000010PT, Tox21_110464, BDBM50013792, CCG-39321, NSC758426, SBB037875, ZINC12503151, AKOS015897587, AKOS024464790, AKOS026749792, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, ZINC100019188, ZINC253917094, CS-2658, DB00703, FCH4114988, KS-5328, MCULE-1665001985, NC00618, NSC-758426, IDI1_000582, Methazolamide (oral, sustained release), NCGC00018188-01, NCGC00018188-02, NCGC00018188-03, NCGC00018188-04, NCGC00018188-05, NCGC00018188-06, NCGC00018188-07, NCGC00022950-03, NCGC00022950-04, NCGC00178022-01, NCGC00178022-02, AN-45878, AS-13272, CC-30264, CPD001453721, CPD001496938, H773, LS-10006, SAM002548986, SAM002589943, ST081366, SBI-0051804.P002, AB0013250, A4364, AB00490015, FT-0603467, S4039, C07764, D00655, K-9905, AB00052336_04, 554M574, A830656, L584601, Methazolamide, VETRANAL(TM), analytical standard, I09-1225, L 584601, SR-05000001844-1, SR-05000001844-2, SR-05000001844-3, BRD-K13356952-001-15-2, BRD-K71053238-001-03-6, BRD-K71053238-001-04-4, (E)-N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)ethanamide, Methazolamide, United States Pharmacopeia (USP) Reference Standard, (E)-N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, 5-Acetylimino-4-methyl-| currency2-1,3,4-thiadiazoline-2-sulfonamide, Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-, (N(Z))-, N-(4-Methyl-2-sulfamoyl-| currency2-1,3,4-thiadiazolin-5-ylidene) acetamide, N-(4-Methyl-2-sulfamoyl-| currency2-1,3,4-thiadiazolin-5-ylidene)acetamide, N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide, 1164547-86-7

ID: 601

InChIKey: FLRUCNJMPLRHQE-MYAXKPMNSA-N
SMILES: CC(C)/C(=C/1\C2[C@]([C@@H](OC1=O)C3=COC=C3)(C([C@H]([C@@]45[C@]26[C@@H]([C@]7(C(C8(CC7([C@]4([C@H]8CC(=O)O)C)OC(O5)(O6)C)C)O)O)O)O)O)C)/O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 54699399
synonyms found at PubChem are:
HYDROLYSIS PRODUCT OF BUSSEIN, Spectrum5_000139, BSPBio_001735, SPECTRUM100117, CHEMBL3039083, CCG-38539, SDCCGMLS-0066307.P001, NCGC00179047-01, SR-05000002773, SR-05000002773-1

ID: 602

InChIKey: FLVRDMUHUXVRET-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)OC2=CC=CC(=C2)C3=C(C4=C(C=C(C=C4)Cl)NC3=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 115113
synonyms found at PubChem are:
L-701324, 142326-59-8, L-701,324, L 701324, UNII-I9WY146163, C21H14ClNO3, L 701,324, CHEMBL31741, 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolone, I9WY146163, compund 13 [PMID: 8182696], 7-Chloro-4-hydroxy-3-(3-pheoxyphenyl)-2(1H)-quinolinone, 2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-pheoxyphenyl)-, SMR000326934, Tocris-0907, AC1L3GJN, Biomol-NT_000206, D0M1WN, MLS000860076, MLS002153302, BPBio1_001264, GTPL4240, SCHEMBL1998890, CHEBI:92140, DTXSID00162016, EX-A587, MolPort-003-941-887, 2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)quinolin-2(1H)-one, HMS2234A14, HMS3267A09, HMS3370N04, BCP14852, BDBM50038168, MFCD00910917, ZINC95541799, AKOS005067008, AKOS026750257, API0026404, CS-4968, NCGC00024864-01, NCGC00024864-02, 940943-34-0, HY-18698, KB-53089, LS-173140, B6499, FT-0687292, L-701, L-701,324, >=98% (HPLC), solid, L701324, SR-01000597439, J-007638, SR-01000597439-1, BRD-K08109516-001-01-1, BRD-K08109516-001-02-9, L-701 324, 7-chloro-2-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-4-one, 7-Chloro-2-hydroxy-3-(3-phenoxyphenyl)-4(1H)-quinolinone, 7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinolin-2-one, 7-chloro-2-hydroxy-3-(3-phenoxyphenyl)-1,4-dihydroquinolin-4-one, 7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE

ID: 603

InChIKey: FMETVQKSDIOGPX-UHFFFAOYSA-N
SMILES: C1CCC(C1)N2C=C(C3=C2N=CN=C3N)C4=CC=C(C=C4)OC5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603792
synonyms found at PubChem are:
213743-31-8, 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, CHEMBL47940, IN1272, KIN001-051, RK-24466, 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR, 4-Amino-5-(4-Phenoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl-Cyclopentane, 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[3,2-d]pyrimidin-7-yl-cyclopentane, 3gen, 3vry, B43, NCGC00015280-01, Lopac-C-8863, D0OZ2S, AC1O7G1S, Lopac0_000450, MLS002153184, SCHEMBL378454, GTPL6003, CTK8E9535, AOB5698, DTXSID90424958, FMETVQKSDIOGPX-UHFFFAOYSA-N, MolPort-003-940-860, HMS2232E04, HMS3229G15, HMS3261I22, HMS3371C06, ZINC2541690, Tox21_500450, BDBM50092228, MFCD04974490, CCG-204542, CS-8050, LP00450, NCGC00015280-02, NCGC00015280-03, NCGC00015280-04, NCGC00015280-05, NCGC00093866-01, NCGC00093866-02, NCGC00261135-01, ACM213743318, SMR001230675, HY-108318, RT-013564, EU-0100450, C 8863, SR-01000075852, J-014016, SR-01000075852-1, 7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine, 4-Amino-5-(4-phenoxyphenyl)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine, 7-Cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3d]pyrimidin-4-ylamine, 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, >=98% (HPLC)

ID: 604

InChIKey: FMGSKLZLMKYGDP-USOAJAOKSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5881
synonyms found at PubChem are:
Dehydroepiandrosterone, DHEA, 53-43-0, PRASTERONE, Dehydroisoandrosterone, Androstenolone, trans-Dehydroandrosterone, 3beta-hydroxyandrost-5-en-17-one, Diandron, Diandrone, Psicosterone, 17-Hormoforin, 17-Chetovis, Prestara, 5-Dehydroepiandrosterone, Andrestenol, Intrarosa, Siscelar plus, 5,6-Didehydroisoandrosterone, Epiandrosterone, 5-dehydro-, dehydroepiandrosterone (dhea), Caswell No. 051F, 5,6-Dehydroisoandrosterone, 5,6-Dehydroisoandrostorone, CCRIS 3277, Prasteronum [INN-Latin], Prasterona [INN-Spanish], 3beta-hydroxy-5-androsten-17-one, (+)-Dehydroisoandrosterone, 3-beta-Hydroxy-5-androsten-17-one, GL 701, Prasterone [INN], Androst-5-en-17-one, 3-hydroxy-, (3beta)-, EPA Pesticide Chemical Code 126510, UNII-459AG36T1B, 5-Androsten-3beta-ol-17-one, Dehydro-epi-androsterone, (3-beta)-3-Hydroxyandrost-5-en-17-one, NSC 9896, EINECS 200-175-5, EM-760, BRN 2058110, (3beta)-3-hydroxyandrost-5-en-17-one, Prasterona, Prasteronum, Androst-5-en-17-one, 3-beta-hydroxy-, CHEMBL90593, (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, CHEBI:28689, NSC9896, FMGSKLZLMKYGDP-USOAJAOKSA-N, 459AG36T1B, Prasterone (INN), DSSTox_CID_379, Androst-5-en-17-one, 3-hydroxy-, (3b)-, Androst-5-en-17-one, 3beta-hydroxy- (8CI), DSSTox_RID_75553, DSSTox_GSID_20379, Astenile, Deandros, AND, Androst-5-en-17-one, 3-hydroxy-, (3.beta.)-, CAS-53-43-0, (1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-14-one, (1S,5S,11S,15S,2R,10R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11,15> ]heptadec-7-en-14-one, SMR000059075, Androst-5-en-17-one, 3.beta.-hydroxy-, SR-01000075815, Prasterone [USAN:INN], D5-Androsten-3beta-ol-17-one, Androst-5-ene-3beta-ol-17-one, 5-Androsten-3.beta.-ol-17-one, Anastar, Fidelin, Inflabloc, Vaginorm, Aslera, 3-|A-hydroxy-5-androsten-17-one, 3-beta-hydroxyandrost-5-en-17-one, 3beta-Hydroxy-D5-androsten-17-one, Fidelin T, NCGC00093802-04, NCGC00093802-06, Biolaif (TN), Dehydroepiandrosternoe, DHEA, Paladin Labs, dehydroepiandrostenedione, trans-de-hydroandrosterone, bmse000665, D00OAW, D0K0EK, DHEA, Neuroscience Pharma, EC 200-175-5, AC1L1LC4, 5,6-didehydroepiandrosterone, BIDD:PXR0080, Lopac0_000368, SCHEMBL24156, Hydroxyandrost-5-en-17-one, 4-08-00-00994 (Beilstein Handbook Reference), MLS001066350, MLS001333231, MLS001333232, MLS001424274, GTPL2370, DTXSID4020379, BCPE00002, DHEA (trans-Dehydroandrosterone), MolPort-003-929-763, 3beta-Hyroxyandrost-5-en-17-one, BCPP000260, EL-10, GL701, HMS2052P11, HMS2090C04, HMS2232K11, IM 28, trans-Dehydroandrosterone, >=99%, 3-beta-hydroxy-5-androsten-17-on, ACT02646, BCP02453, Dehydroepiandrosterone, Paladin Labs, IPL-1001, NSC-9896, ZINC3807917, 3beta-Hydroxyandrost-5-ene-17-one, Tox21_111222, Tox21_201996, Tox21_302761, BDBM50223368, CMC_13435, Delta5-androsten-3-beta-ol-17-one, DL-373, GL-701, LMST02020021, MFCD00003613, PB-007, s2604, SBB012501, 3.beta.-Hydroxyandrost-5-en-17-one, 5-Androsten-3beta-ol-17-one; DHEA, AKOS007930299, AKOS015951378, Tox21_111222_1, BCP9000602, CCG-101190, CS-1667, DB01708, EBD1328208, GS-0906, IP-1001, LS-7296, NC00440, SH-K-04828, Androst-5-en-17-one, 3beta-hydroxy-, NCGC00093802-09, NCGC00256412-01, NCGC00259545-01, (3beta)-3-Hydroxyandrost-5-ene-17-one, AC-28716, AJ-45664, AK125048, AN-24410, CC-26313, HY-14650, NCI60_042215, Prasterone (DHEA; Dehydroepiandrosterone), ST069381, Dehydroepiandrosterone, Neuroscience Pharma, AB0007943, AB1009532, TR-018899, D0044, EU-0100368, C01227, D 4000, D-0340, D08409, J10065, M-1336, AB00375810-06, AB00375810_09, Androst-5-en-17-one, 3-hydroxy-, (3-beta)-, C-18147, SR-01000075815-1, SR-01000075815-4, BRD-K41256143-001-12-7, Androst-5-en-17-one, 3-hydroxy-, (3-beta)- (9CI), Androst-5-en-17-one, 3-hydroxy-, (3beta)- (9CI), Z2213891300, 1A9D2040-240C-427D-ADE4-0CB700B785CB, Prasterone (DHEA; Dehydroepiandrosterone) 1.0 mg/ml in Acetonitrile, (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one, (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-3,4,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one, 105597-37-3, 108673-53-6, 9013-35-8

ID: 605

InChIKey: FMHHVULEAZTJMA-UHFFFAOYSA-N
SMILES: CC1=CC(=O)OC2=C1C=C3C=C(OC3=C2C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5585
synonyms found at PubChem are:
trioxsalen, Trioxysalen, Trisoralen, 3902-71-4, Trimethylpsoralen, 4,5',8-Trimethylpsoralen, Elder 8011, Trioxisaleno, Trioxysalene, Trioxysalenum, 2',4,8-Trimethylpsoralen, 4,5',8-Trimethylpsoralene, NSC-71047, 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one, UNII-Y6UY8OV51T, NSC71047, Trioxysalene [INN-French], Trioxysalenum [INN-Latin], Trioxisaleno [INN-Spanish], NSC 71047, TRIOXSALIN, 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-, EINECS 223-459-0, 4,8,5'-Trimethylpsoralen, BRN 0221723, Y6UY8OV51T, 2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one, 2,5,9-trimethylfuro[3,2-g]chromen-7-one, CHEBI:28329, 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one, FMHHVULEAZTJMA-UHFFFAOYSA-N, 7-Oxo-2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyron, 7H-Furo(3,2-g)(1)benzopyran-7-one, 2,5,9-trimethyl-, NCGC00016643-01, CAS-3902-71-4, 6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid gamma-lactone, DSSTox_CID_3716, DSSTox_RID_77160, DSSTox_GSID_23716, Trioxsalen [USAN], SR-01000812969, Trioxsalen [USAN:USP], 2,5,9-Trimethylpsoralen, 4,5,8-Trimethylpsoralen, antipsoriatic, Trioxalen, Trixsalen, Trisoralen (TN), Trioxsalen (USP), Prestwick_148, Trioxysalen [INN], LACTONE, 4,8-Trimethylpsoralen, Spectrum_000169, 4,8-Trimethylpsoralene, 2',8-Trimethylpsoralen, AC1L1KOB, Trioxysalen (JAN/INN), Prestwick0_000709, Prestwick1_000709, Prestwick2_000709, Prestwick3_000709, Spectrum2_001083, Spectrum3_001378, Spectrum4_000883, Spectrum5_001557, D0FA2O, SCHEMBL1252, CHEMBL1475, Oprea1_203343, BSPBio_000897, BSPBio_002936, KBioGR_001286, KBioSS_000649, 5-19-04-00472 (Beilstein Handbook Reference), MLS001173417, DivK1c_000380, SPECTRUM1500596, SPBio_001126, SPBio_002818, BPBio1_000987, MEGxm0_000462, ZINC2226, DTXSID3023716, ACon0_000603, ACon1_000251, HMS501C22, KBio1_000380, KBio2_000649, KBio2_003217, KBio2_005785, KBio3_002156, MolPort-001-740-054, NINDS_000380, HMS1570M19, HMS1921I05, HMS2092A12, HMS2097M19, HMS2879M06, HMS3714M19, Pharmakon1600-01500596, 7H-Furo[3, 2,5,9-trimethyl-, HY-B1157, Tox21_110541, ANW-41902, CCG-39937, MFCD00005010, NSC757371, AKOS015912601, Tox21_110541_1, Trioxsalen, >=98% (HPLC), powder, ACM3902714, CS-4760, DB04571, KS-5184, MCULE-5301264270, NSC-757371, SDCCGMLS-0066609.P001, IDI1_000380, NCGC00016643-02, NCGC00016643-03, NCGC00016643-04, NCGC00016643-05, NCGC00016643-06, NCGC00016643-09, NCGC00016643-10, NCGC00094804-01, NCGC00094804-02, NCGC00178384-01, NCGC00178384-02, NCGC00178384-03, CC-35440, LS-70743, NCI60_038883, SMR000538905, ST083486, ZB000511, SBI-0051547.P002, AB2000428, TR-015676, FT-0603651, W0082, 4,7,9-trimethylfurano[3,2-g]chromen-2-one, A-8462, BENZOFURANACRYLIC ACID,2,7-TRIMETHYL-,, C09314, D01034, EN300-122631, J10195, 4,7,9-trimethyl-2H-furo[3,2-g]chromen-2-one, AB00052119_09, 2,5,9-trimethyl-7-furo[3,2-g][1]benzopyranone, 902T714, A824380, C-13067, Trimethylpsoralen;Trioxysalen;Trisoralen;Trisoralen, 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one #, SR-01000812969-2, SR-01000812969-5, SR-01000812969-6, SR-01000812969-7, 2,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one, BRD-K54790157-001-06-4, BRD-K54790157-001-10-6, I14-48205, Z1551429738, 5-Benzofuranacrylic acid,2,7-trimethyl-, .delta.-lactone, Trioxsalen, United States Pharmacopeia (USP) Reference Standard, 5-Benzofuranacrylic acid, 6-hydroxy-.beta.,2,7-trimethyl-, .delta.-lactone, 6-hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactone

ID: 606

InChIKey: FMKJUUQOYOHLTF-OWOJBTEDSA-N
SMILES: C(/C=C/C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5310987
synonyms found at PubChem are:
TACA, (E)-4-Amino-2-butenoic acid, 38090-53-8, TRANS-4-AMINOCROTONICACID, t-4-AMINOCROTONIC ACID (TACA), trans-4-Aminocrotonic acid, CHEMBL33086, NCGC00024485-02, 4-aminobut-2-enoic acid, DSSTox_CID_25648, DSSTox_RID_81026, DSSTox_GSID_45648, CAS-38090-53-8, 4-amino-2-butenoic acid, E-4-Amino-2-butenoic acid, 2-Butenoic acid, 4-amino-, SR-01000075646, 25747-40-4, 4 Aminocrotonic Acid, AC1NSJS2, Spectrum5_001675, Biomol-NT_000233, 4-Amino-but-2-enoic acid, Lopac0_001145, BSPBio_002528, SCHEMBL232135, SCHEMBL489325, SPECTRUM1502123, (E)-4-aminobut-2-enoic acid, BPBio1_000683, DTXSID8045648, (E)-4-amino-but-2-enoic acid, MolPort-003-959-679, HMS3263F11, ZINC2558023, Tox21_110902, Tox21_501145, BDBM50087271, CCG-39246, PDSP1_000613, PDSP2_000610, AKOS022632601, Tox21_110902_1, 2-Butenoic acid, 4-amino-, (2E)-, API0004306, LP01145, NCGC00024485-03, NCGC00024485-04, NCGC00024485-05, NCGC00024485-06, NCGC00024485-07, NCGC00024485-08, NCGC00261830-01, (E)-4-Amino-but-2-enoic acid (TACA), B6217, EU-0101145, EN300-188085, T 1694, SR-01000075646-1, SR-01000075646-3

ID: 607

InChIKey: FMKJUUQOYOHLTF-UPHRSURJSA-N
SMILES: C(/C=C\C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603697
synonyms found at PubChem are:
cis-4-Aminocrotonic acid, CACA, 4-aminocrotonic acid, (Z)-4-aminobut-2-enoic acid, cis-aminocrotonic acid, CHEMBL32307, 55199-25-2, 4-aminobut-2-enoic acid, Tocris-0181, Lopac-A-201, AC1O7FZA, Lopac-T-1694, Biomol-NT_000234, D0O9UH, Lopac0_000108, 4-Amino-cis-2-butenoic acid, SCHEMBL339699, BPBio1_000376, GTPL4148, (Z)-4-Amino-2-butenoic acid, (Z)-4-Amino-but-2-enoic acid, HMS3260E18, Tox21_500108, BDBM50087277, PDSP1_000243, PDSP2_000242, ZINC29227709, AKOS006272743, CCG-204203, LP00108, NCGC00015016-01, NCGC00015016-02, NCGC00015016-03, NCGC00015016-04, NCGC00015016-05, NCGC00015016-06, NCGC00024485-01, NCGC00093605-01, NCGC00093605-02, NCGC00093605-03, NCGC00260793-01, A-201, EU-0100108, SR-01000076226, SR-01000076226-1

ID: 608

InChIKey: FMMWHPNWAFZXNH-UHFFFAOYSA-N
SMILES: C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C4C(=CC=C5)C=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2336
synonyms found at PubChem are:
benzo[a]pyrene, 50-32-8, 3,4-Benzopyrene, BENZO(A)PYRENE, benzo[pqr]tetraphene, 3,4-Benzpyrene, Benzpyrene, benzo[def]chrysene, 6,7-Benzopyrene, Benz[a]pyrene, 3,4-BP, 3,4-Benz[a]pyrene, 3,4-Benzopirene, 3,4-Benzpyren, Benzo[d,e,f]chrysene, Benz(a)pyrene, (B(a)P), B(a)P, BP, 3,4 Benzpyrene, RCRA waste number U022, 3,4-Benz(a)pyrene, Benzo(d,e,f)chrysene, NSC 21914, 3,4-Benzo(a)pyrene, B[a]p, 3,4-Benzpyren [German], Benzo[A]-Pyrene, CCRIS 76, Benzo(def)chrysene, 3,4-benzylpyrene, 3,4-Benzopirene [Italian], UNII-3417WMA06D, CHEBI:29865, HSDB 2554, FMMWHPNWAFZXNH-UHFFFAOYSA-N, EINECS 200-028-5, RCRA waste no. U022, CHEMBL31184, AI3-50461, 3417WMA06D, Coal tar pitch volatiles: benzo(a)pyrene, Benzo(a)pyrene [Polycyclic aromatic compounds], Benzo(a)pyrene [Polycyclic aromatic hydrocarbons], 3,4 Benzopyrene, Benzo[a]pyrene (BaP), Benzo(a)pyrene radical cation, 3,4-Benzypyrene, Benzo(a)pyrene, radical ion(1+), Benzo(a)pyrene, radical ion(1-), Benzo[d,f]chrysene, Benzo(a)pyrene, labeled with tritium, Benzo Pyrene[BAP], Benzo(3,4)pyrene, radical ion(1+), Spectrum_001871, Benzo[a]pyrene solution, ACMC-209sok, SpecPlus_000953, AC1Q1HKZ, DSSTox_CID_139, Spectrum2_001081, Spectrum3_001695, Spectrum4_000609, Spectrum5_001824, Epitope ID:117721, AC1L1DG9, DSSTox_RID_75392, DSSTox_GSID_20139, BSPBio_003250, KBioGR_001138, KBioSS_002390, KSC269M1J, MLS002695983, BIDD:ER0497, DivK1c_007049, SPBio_001122, 3,4-Benzopyrene (carcinogen), DTXSID2020139, CTK1G9614, KBio1_001993, KBio2_002385, KBio2_004953, KBio2_007521, KBio3_002470, Benzo[a]pyrene, 96% 100mg, MolPort-001-785-827, HMS3089C04, NSC21914, ZINC1530818, Benzo[a]pyrene, >=96% (HPLC), Tox21_200710, ANW-41442, BDBM50137506, CCG-39759, LS-139, NSC-21914, SBB061395, AKOS015907666, 3,4-Benzopyrene(purifiedbysublimation), AM61580, CB-1807, CS-7789, MCULE-1109963029, RTR-017988, CAS-50-32-8, WLN: L D6 B6666 2AB TJ, NCGC00178185-01, NCGC00178185-02, NCGC00258264-01, 34505-58-3, 42299-33-2, 6699-27-0, AJ-26702, AK-49838, AN-41549, BR-49838, CC-24344, CJ-05216, CJ-24042, EN002216, KB-47598, NCI60_001824, SC-08054, SMR000393676, AX8115689, DB-071166, HY-107377, TR-017988, 4CH-007056, B0085, Benzo(a)pyrene 10 microg/mL in Acetonitrile, FT-0614185, ST24030136, ST45022245, W6563, Benzo(a)pyrene 100 microg/mL in Acetonitrile, Benzo(a)pyrene 100 microg/mL in Cyclohexane, 4809-EP2270014A1, 4809-EP2270895A2, 4809-EP2272517A1, 4809-EP2277880A1, 4809-EP2277898A2, 4809-EP2278637A1, 4809-EP2284157A1, 4809-EP2292088A1, 4809-EP2292610A1, 4809-EP2292630A1, 4809-EP2295424A1, 4809-EP2295428A2, 4809-EP2298735A1, 4809-EP2298744A2, 4809-EP2298780A1, 4809-EP2302015A1, 4809-EP2305250A1, 4809-EP2305689A1, 4809-EP2305825A1, 4809-EP2308852A1, 4809-EP2311820A1, 4809-EP2316827A1, 4809-EP2316836A1, 4809-EP2316937A1, 4809-EP2371805A1, 4809-EP2374895A1, C07535, J10073, S-4361, A828066, A828067, Benzo[a]pyrene, vial of 1 g, analytical standard, C-29981, I14-2877, BRD-K09668667-001-02-0, Benzo[a]pyrene, certified reference material, TraceCERT(R), UNII-0TNN3Q0D4D component FMMWHPNWAFZXNH-UHFFFAOYSA-N, Benzo[a]pyrene, analytical standard, for environmental analysis, BENZO(A)PYRENE (SEE ALSO: BENZO(E)PYRENE (CAS 192-97-2)), Benzo[a]pyrene solution, 100 mug/mL in cyclohexane, analytical standard, Benzo[a]pyrene solution, certified reference material, 100 mug/mL in methylene chloride, 819804-28-9, Benzo[a]pyrene solution, certified reference material, TraceCERT(R), 1000 mug/mL in acetone, Benzo[a]pyrene solution, certified reference material, TraceCERT(R), 200 mug/mL in methylene chloride

ID: 609

InChIKey: FMOKUKPRJSMPOI-QRPNPIFTSA-N
SMILES: CC(=O)C[C@@H]1CCCCN1.Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "D Zhang" "Y Luo" "JW Hanrahan" "R Robert" "KA Teske" "GW Carlile"

CID is 72942005
synonyms found at PubChem are:
UNII-Q107JES56Y, Q107JES56Y, Pelletierine hydrochloride, (+)-, 2-Propanone, 1-(2S)-2-piperidinyl-, hydrochloride (1:1), 1250851-48-9, UNII-516910XH33 component FMOKUKPRJSMPOI-QRPNPIFTSA-N

ID: 610

InChIKey: FMOKUKPRJSMPOI-UHFFFAOYSA-N
SMILES: CC(=O)CC1CCCCN1.Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "D Zhang" "Y Luo" "JW Hanrahan" "R Robert" "KA Teske" "GW Carlile"

CID is 16667749
synonyms found at PubChem are:
PELLETIERINE HYDROCHLORIDE, 5984-61-2, Isopelletierine hydrochloride, Pelletierine hydrochloride [MI], (+/-)-Pelletierine hydrochloride, Pelletierine hydrochloride, (+/-)-, SPECTRUM300553, SCHEMBL4270933, 2-Propanone, 1-(2-piperidinyl)-, hydrochloride (1:1), CHEMBL3039396, CTK1E6396, CCG-38558, NCGC00095603-01, 2-Propanone, 1-(2-piperidinyl)-, hydrochloride, SR-05000002412, SR-05000002412-1

ID: 611

InChIKey: FMQURVHYTBGYSQ-UHFFFAOYSA-H
SMILES: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C4C(=CC(=CC4=C(C=C3)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC5=C6C(=CC(=CC6=C(C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4465
synonyms found at PubChem are:
NF-023, GTPL4266, MolPort-003-983-646, 1,3,5-trisodium 8-{[3-({[3-({4,6,8-tris[(sodiooxy)sulfonyl]naphthalen-1-yl}carbamoyl)phenyl]carbamoyl}amino)benzene]amido}naphthalene-1,3,5-trisulfonate, NF 023, 104869-31-0, NF 023 hydrate, CHEMBL216504, hexasodium 8-[[3-[[3-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]benzoyl]amino]naphthalene-1,3,5-trisulfonate, NCGC00016181-01, Lopac-N-8652, D0B7MW, AC1O1BH0, AC1L1I87, HMS3262B21, MFCD11046019, AKOS024456482, CCG-208808, LP00810, NCGC00016181-02, NCGC00094143-01, NCGC00261495-01, RT-014691, EU-0100810, N 8652, J-001279, 8,8'-(carbonyl-bis(imino-3,1-phenylenecarbonylimino))bis(naphthalene-1,3,5-trisulfonic acid)-hexasodium salt, 8,8'-[carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt, 8,8'-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt

ID: 612

InChIKey: FMZXNVLFJHCSAF-DNVCBOLYSA-N
SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 21743
synonyms found at PubChem are:
CEFALONIUM, Cephalonium, 5575-21-3, Cefalonum, Cefalonium hydrate, Cefalonium [INN-Latin], Cefalonio [INN-Spanish], Lilly 41071, UNII-K2P920217W, EINECS 226-948-7, BRN 4169337, C20H18N4O5S2, K2P920217W, 7-(alpha-Thienylacetamido)-3-(4-carbamoylpyridinomethyl)-3-cephem-4-carboxylic acid, DSSTox_CID_25388, DSSTox_RID_80845, DSSTox_GSID_45388, (6R,7R)-3-(4-(4-Carbamoyl-1-pyridiniomethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylat, 3-(4-Carbamoylpyridylmethyl)-8-oxo-7-(alpha-(thien-2-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2carbonsaeure, Cefalonio, (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Cefalonium [INN], Pyridinium, 4-carbamoyl-1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-aza-bicyclo(4.2.0)oct-2-en-3-yl)methyl)- hydroxide, inner salt, Cefalonium [INN:BAN], NCGC00016657-01, Cefalonium (BAN), CAS-5575-21-3, Cepravin dry cow (TN), AC1L2IZP, SCHEMBL125252, CHEMBL2105567, DTXSID5045388, CHEBI:95345, CTK8F8515, MolPort-006-117-037, HMS1571G13, HMS2098G13, Pharmakon1600-01505997, Tox21_110548, NSC759292, AKOS026749802, Tox21_110548_1, API0006602, CCG-213999, NSC-759292, NCGC00179310-01, NCGC00179310-03, Q767, LS-132299, AB00513991, D07634, AB00513991_02

ID: 613

InChIKey: FMZYZILCSUARND-ZENOOKHLSA-N
SMILES: C[C@]12CC[C@H](C[C@@H]1CCC3=C2C=C(C=C3)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6728946
synonyms found at PubChem are:
12-METHOXY-4,4-BISNOR-5alpha-8,11,13-PODOCARPATRIEN-3-OL, SPBio_001190, Spectrum2_001255, AC1O9AU6, CHEMBL3039053, CCG-39129, (2R,4aS,10aS)-6-methoxy-4a-methyl-2,3,4,9,10,10a-hexahydro-1H-phenanthren-2-ol

ID: 614

InChIKey: FNDGLVOYAQNQPE-UHFFFAOYSA-N
SMILES: CN(C(CN1CCCC1)C2=CC(=CC=C2)OCC(=O)O)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 129407
synonyms found at PubChem are:
ICI 204,448 hydrochloride, 121264-04-8, ICI-204,448 hydrochloride, Ici 204448, 4,4'-(2-ACETYL-1,3-GLYCEROL)BISANHYDRO MELLITATE, MLS002153186, (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride, R,S-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl] phenoxy]-acetic acid hydrochloride, SR-01000075504, SMR001230677, AC1L2VJX, SCHEMBL3167955, CHEMBL1256750, CTK8F0814, FNDGLVOYAQNQPE-UHFFFAOYSA-N, MolPort-003-941-768, Tox21_500704, ICI 204,448 hydrochloride, solid, MFCD00153814, AKOS024458659, API0007622, CCG-222008, LP00704, N(1)-(2-(N-Methyl-3,4-dichlorophenylacetamido)-2-(3-carboxyphenyl)ethyl)pyrrolidine, NCGC00094056-01, NCGC00261389-01, RT-013314, EU-0100704, I-122, J-004474, SR-01000075504-1, SR-01000075504-3, 2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methylamino]-2-pyrrolidin-1-ylethyl]phenoxy]acetic acid hydrochloride, 3-{1-[2-(3,4-dichlorophenyl)-N-methylacetamido]-2-(pyrrolidin-1-yl)ethyl}phenoxyacetic acid hydrochloride, Acetic acid, (3-(1-(((3,4-dichlorophenyl)acetyl)methylamino)-2-(1-pyrrolidinyl)ethyl)phenoxy)-, monohydrochloride, (+-)-

ID: 615

InChIKey: FNPXMHRZILFCKX-KAJVQRHHSA-N
SMILES: CCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)OC(=O)OCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6714002
synonyms found at PubChem are:
PREDNICARBATE, Dermatop, 73771-04-7, Peitel, Hoe 777, Hoe-777, Dermatop E emollient, Prednitop, UNII-V901LV1K7D, Dermatop (TN), Prednicarbate (USP/INN), S-770777, MLS002154121, V901LV1K7D, [2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate, Prednicarbatum [INN-Latin], Prednicarbato [INN-Spanish], S-77 0777, Prednicarbato, Prednicarbatum, EINECS 277-590-3, S 770777, Prednicarbat, Regenit, 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 17-(ethyl carbonate) 21-propionate, NCGC00016926-01, Pregna-1,4-diene-3,20-dione, 17-((ethoxycarbonyl)oxy)-11-hydroxy-21-(1-oxopropoxy)-, (11beta)-, Prednicarbate [USAN:USP:INN:BAN], CAS-73771-04-7, Prestwick0_001044, Prestwick1_001044, Prestwick2_001044, Prestwick3_001044, D09IEE, SCHEMBL3941, DSSTox_CID_25502, DSSTox_RID_80919, DSSTox_GSID_45502, BSPBio_000968, SPBio_002904, AC1O8Q04, BPBio1_001066, GTPL7605, CHEMBL1200386, DTXSID9045502, CHEBI:135791, HMS1571A10, HMS2098A10, HMS2230O11, HMS3715A10, ZINC3938652, Tox21_110687, AKOS025402043, AC-3521, AN-6763, API0009173, CCG-221044, DB01130, NCGC00179357-01, BC226387, SC-81331, SMR001233428, AB2000755, AB00514017, D05601, 771P047, Prednisolone 17-(Ethyl Carbonate) 21-Propionate, SR-01000841201, Q-101379, SR-01000841201-2, BRD-K46137903-001-03-3, S 77 0777, S 77-0777, (11|A)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, [2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate, Pregna-1,4-diene-3,20-dione,17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-, (11b)-

ID: 616

InChIKey: FNQQBFNIYODEMB-UHFFFAOYSA-N
SMILES: CC1=C(C=C2C(=C1)CCCS2(=O)=O)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4165
synonyms found at PubChem are:
meticrane, 1084-65-7, Arresten, Fontiliz, 6-Methylthiochroman-7-sulfonamide 1,1-dioxide, Meticran, Meticranum [INN-Latin], Meticrano [INN-Spanish], UNII-I7EKN1924Q, Meticrane [INN:DCF:JAN], C10H13NO4S2, EINECS 214-112-4, E-103-E, SD 17102, I7EKN1924Q, 6-Methyl-7-sulfamido-thiochroman-1,1-dioxide, Thiochroman-7-sulfonamide, 6-methyl-, 1,1-dioxide, NCGC00016561-01, CAS-1084-65-7, 2H-1-Benzothiopyran-7-sulfonamide, 3,4-dihydro-6-methyl-, 1,1-dioxide, 6-Methyl-3,4-dihydro-2H-1-benzothiopyran-7-sulfonamide 1,1-dioxide, DSSTox_CID_25346, DSSTox_RID_80814, DSSTox_GSID_45346, Meticranum, Meticrano, 6-methyl-1,1-dioxo-3,4-dihydro-2H-thiochromene-7-sulfonamide, 6-Methylthiochroman-7-sulphonamide 1,1-dioxide;6-Methylthiochroman-7-sulfonamide 1,1-dioxide, SR-01000838874, Arresten (TN), Prestwick_881, AC1Q6TPB, Prestwick0_000011, Prestwick1_000011, Prestwick2_000011, Prestwick3_000011, 6-methyl-7-sulfamoylthiochroman 1,1-dioxide, Meticrane (JP17/INN), AC1L1HK4, SCHEMBL49070, BSPBio_000041, MLS002154170, Meticrane, analytical standard, SPBio_001962, BPBio1_000047, ZINC1718, CHEMBL1318341, DTXSID9045346, CHEBI:31839, CTK4A6055, FNQQBFNIYODEMB-UHFFFAOYSA-N, MolPort-002-070-500, HMS1568C03, HMS2095C03, HMS2235D06, HMS3371D22, HMS3712C03, Pharmakon1600-01506077, HY-B0908, Tox21 110495, Tox21_110495, 2541AH, NSC759309, AKOS016014038, Tox21_110495_1, API0019488, CCG-214046, NSC-759309, NCGC00016561-02, NCGC00016561-05, AJ-08074, SD-17102, SMR001233468, ZB000397, SBI-0207038.P001, AX8140024, KB-249210, LS-152602, TR-002132, FT-0725174, 6-Methylthiochroman-7-sulfonamide1,1-dioxide, D01605, C-54999, J-002149, SR-01000838874-2, SR-01000838874-3, BRD-K58265391-001-03-6, BRD-K58265391-001-06-9, 6-Methyl-3,4-dihydro-2H-thiochromene-7-sulfonamide 1,1-dioxide, 2H-1-Benzothiopyran-7-sulfonamide,3,4-dihydro-6-methyl-, 1,1-dioxide, 3,4-Dihydro-6-methyl-2H-1-benzothiopyran-7-sulfonamide 1,1-dioxide, 3,4-Dihydro-6-methyl-2H-1-benzothiopyran-7-sulfonamide- 1,1-dioxide, 6-Methyl-1-thia-1,2,3,4-tetrahydronaphthalene-7-sulfonamide 1,1-dioxide, 2H-1-Benzothiopyran-7-sulfonamide, 3,4-dihydro-6-methyl-, 1,1-dioxide (9CI)

ID: 617

InChIKey: FNWNGQGTFICQJU-UHFFFAOYSA-N
SMILES: CC1=C(C(=C(C=C1)C(C)C)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11052
synonyms found at PubChem are:
2-Hydroxy-3-isopropyl-6-methylbenzoic acid, 548-51-6, o-Thymotic acid, o-Thymotinic acid, Orthothymotic acid, o-Thymolcarboxylic acid, 2-Thymolcarboxylic acid, 2-Thymotic acid, ORTHOTHYMOTINIC ACID, 3-Isopropyl-6-methylsalicylic acid, 6-Methyl-3-isopropylsalicylic acid, 3-Hydroxy-2-p-cymenecarboxylic acid, 3-Isopropyl-6 methyl salicylic acid, UNII-GF566F3K7L, 2-Methyl-5-isopropylsalicyclic acid, EINECS 208-949-4, NSC 68360, 3-Hydroxy-p-cymene-2-carboxylic acid, BRN 2578282, Benzoic acid, 2-hydroxy-6-methyl-3-(1-methylethyl)-, GF566F3K7L, p-CYMENE-2-CARBOXYLIC ACID, 3-HYDROXY-, 2-Hydroxy-6-methyl-3-(1-methylethyl)benzoic acid, 2-hydroxy-6-methyl-3-propan-2-ylbenzoic acid, Benzoic acid,2-hydroxy-6-methyl-3-(1-methylethyl)-, o-Thymotinsaure, Spectrum_001420, ACMC-1AVNZ, AC1L1WIK, Spectrum2_000438, Spectrum3_001779, Spectrum4_000088, Spectrum5_001130, AC1Q1OF7, BSPBio_003277, KBioGR_000356, KBioSS_001900, 3-10-00-00629 (Beilstein Handbook Reference), MLS002207117, SCHEMBL503619, SPBio_000456, CHEMBL1905986, CHEBI:93677, CTK5A2665, KBio2_001900, KBio2_004468, KBio2_007036, KBio3_002778, DTXSID80203279, FNWNGQGTFICQJU-UHFFFAOYSA-N, MolPort-001-792-258, ZINC389607, ALBB-014373, NSC68360, NSC76970, 5425AE, CCG-40250, NSC-68360, NSC-76970, AKOS005174254, VZ24721, 1012-86-8 (mono-hydrochloride salt), LS-58918, SMR001306720, DB-052656, KB-173041, TC-170544, FT-0632365, R1396, 2-Hydroxy-3-Isopropyl-6-Methyl-Benzoic Acid, 2-hydroxy-6-methyl-3-(propan-2-yl)benzoic acid, 6-methyl-2-oxidanyl-3-propan-2-yl-benzoic acid, 2-Hydroxy-3-isopropyl-6-methylbenzoic acid, 98%, A830383, Benzoicacid,2-hydroxy-6-methyl-3-(1-methylethyl)-, BRD-K95788524-001-02-4, I01-16067, Benzoic acid, 2-hydroxy-6-methyl-3-(1-methylethyl)- (9CI), InChI=1/C11H14O3/c1-6(2)8-5-4-7(3)9(10(8)12)11(13)14/h4-6,12H,1-3H3,(H,13,14

ID: 618

InChIKey: FNYLWPVRPXGIIP-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=NC3=C(N=C2N)N=C(N=C3N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5546
synonyms found at PubChem are:
triamterene, 396-01-0, 6-phenylpteridine-2,4,7-triamine, 2,4,7-Triamino-6-phenylpteridine, Dyrenium, Triamteren, Dytac, Pterofen, Pterophene, Triamteril, Triteren, Ademin, Diurene, Noridil, Taturil, Teridin, Urocaudal, Ademine, Jatropur, Noridyl, Triampur, Diren, Ditak, Dyren, Teriam, Tri-Span, Triamteril complex, Trispan, Diucelpin, 6-Phenyl-2,4,7-pteridinetriamine, Triamterenum, Triamthiazid, Dinazide, Diutensat, Diuteren, Dyberzide, Dytenzide, Esiteren, Hidiurese, Hypertorr, Jenateren, Kalspare, Masuharmin, Renezide, Triamizide, Tricilone, Triurene, Amteren, Diarol, Hydrene, Isobar, Nephral, Reviten, Trizid, Uretren, Anjal, Dazid, Turfa, Apo-triazide, Thiazid Wolff, 2,4,7-Pteridinetriamine, 6-phenyl-, Ademin(e), Triamterena, Triazide, Fluss 40, SALI-PUREN, 6-Phenyl-2,4,7-triaminopteridine, SKF 8542, SK&F 8542, Triamterenum [INN-Latin], Triamterena [INN-Spanish], Triamterine, pter ophene, Pteridine, 2,4,7-triamino-6-phenyl-, 2,4,7-Triamino-6-fenilpteridina, UNII-WS821Z52LQ, Dyrenium (TN), BRN 0266723, CCRIS 5872, TRIAMTERENE USP, Pteridine deriv. 11, HSDB 3405, 2,4,7-Triamino-6-fenilpteridina [Italian], NCI C56042, C12H11N7, Triamterene [USAN:INN:BAN:JAN], EINECS 206-904-3, NSC 77625, NSC 639359, SK-8542, AI3-60017, WS821Z52LQ, NCI-C56042, NSC77625, NSC-77625, SK&F-8542, NCGC00016016-10, CAS-396-01-0, 6-PHENYL-2,4,7-TRIAMINO PTERIDINE, DSSTox_CID_1373, T 4143, DSSTox_RID_76117, DSSTox_GSID_21373, SR-01000002968, Triamtereno, Prestwick_480, Ademine(Triamterene), Dyazide (Salt/Mix), Triamterene [USAN:USP:INN:BAN:JAN], Spectrum_000508, Triamterene, >=99%, Prestwick0_000034, Prestwick1_000034, Prestwick2_000034, Prestwick3_000034, Spectrum2_000938, Spectrum3_001372, Spectrum4_000366, Spectrum5_001034, Lopac-T-4143, ACMC-1CT1F, CHEMBL585, D00NKB, Jorba Brand of Triamterene, AC1L1KL5, AC1Q52QZ, NCIOpen2_004741, Lopac0_001196, Oprea1_825704, SCHEMBL40707, BSPBio_000127, BSPBio_002924, KBioGR_000831, KBioSS_000988, 5-26-17-00447 (Beilstein Handbook Reference), KSC492C7T, MLS000069431, ARONIS23836, BIDD:GT0534, DivK1c_000433, SPECTRUM1500589, SPBio_000876, SPBio_002048, BDBM6644, BPBio1_000141, CHEBI:9671, Goldshield Brand of Triamterene, GTPL4329, Wellspring Brand of Triamterene, Jsp006872, Triamterene (JP15/USP/INN), Triamterene (JP17/USP/INN), 2,7-Triamino-6-phenylpteridine, 6-Phenyl-2,7-triaminopteridine, DTXSID6021373, CTK3J2179, HMS501F15, KBio1_000433, KBio2_000988, KBio2_003556, KBio2_006124, KBio3_002144, FNYLWPVRPXGIIP-UHFFFAOYSA-N, MolPort-001-641-070, NINDS_000433, HMS1568G09, HMS2092O17, HMS2095G09, HMS2232B04, HMS3259C08, HMS3263P13, HMS3371D10, HMS3652E10, HMS3712G09, Pharmakon1600-01500589, ZINC120286, 2,7-Pteridinetriamine, 6-phenyl-, Pteridine,4,7-triamino-6-phenyl-, BCP28855, EBD44439, HY-B0575, KS-00000X8I, KS-000046GO, 2,4,7-triamino-6-phenyl-pteridine, Tox21_110283, Tox21_202021, Tox21_302833, Tox21_501196, ANW-74763, BBL023360, CCG-40090, MFCD00006708, NSC639359, NSC757367, s4080, SBB017574, STK300348, AKOS003790819, Tox21_110283_1, CS-2682, DB00384, LP01196, LS-1250, MCULE-5832721534, NC00544, NSC-757367, RTR-015817, IDI1_000433, SmithKline Beecham Brand of Triamterene, SMP1_000147, NCGC00016016-01, NCGC00016016-02, NCGC00016016-03, NCGC00016016-04, NCGC00016016-05, NCGC00016016-06, NCGC00016016-07, NCGC00016016-08, NCGC00016016-09, NCGC00016016-11, NCGC00016016-12, NCGC00016016-13, NCGC00016016-14, NCGC00016016-15, NCGC00016016-16, NCGC00016016-18, NCGC00023458-03, NCGC00023458-04, NCGC00023458-05, NCGC00023458-06, NCGC00023458-07, NCGC00256495-01, NCGC00259570-01, NCGC00261881-01, AC-14066, AJ-11688, AN-23435, AS-12471, CJ-00900, CPD000059118, KB-67376, SAM002554937, SC-77320, SMR000059118, ST093702, ZB004096, SBI-0051163.P003, AB0011988, TR-015817, AB00052116, B2275, BB 0256885, EU-0101196, FT-0609936, ST24029840, Triamterene 1.0 mg/ml in Dimethyl Sulfoxide, Dyrenium|||2,4,7-Triamino-6-phenylpteridine, D00386, WLN: T66 BN DN GN JNJ CZ EZ HR& IZ, Z-0803, AB00052116_13, AB00052116_14, 396T010, A824641, I06-1678, SR-01000002968-2, SR-01000002968-4, SR-01000002968-6, BRD-K92049597-001-05-9, BRD-K92049597-001-10-9, Z275128596, Triamterene, European Pharmacopoeia (EP) Reference Standard, Triamterene, United States Pharmacopeia (USP) Reference Standard, Triamterene, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 619

InChIKey: FOCVUCIESVLUNU-UHFFFAOYSA-N
SMILES: C1CN1P(=S)(N2CC2)N3CC3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5453
synonyms found at PubChem are:
thiotepa, THIO-TEPA, 52-24-4, Triethylenethiophosphoramide, Thiophosphamide, Tiofosfamid, Tiofosyl, Thiofozil, Tespamin, Thioplex, Tiofozil, Girostan, Oncotepa, Tespamine, Thiotef, Stepa, Tio-tef, Thio-Tep, Oncotiotepa, Tifosyl, Oncothio-tepa, TESPA, TSPA, Thio-tepa S, Ledertepa, Thiotriethylenephosphoramide, TIO TEF, N,N',N''-Triethylenethiophosphoramide, Tris(1-aziridinyl)phosphine sulfide, tepadina, 1,1',1''-phosphorothioyltriaziridine, Thiophosphamidum, Triethylene thiophosphoramide, Triaziridinylphosphine sulfide, Tri(aziridin-1-yl)phosphine sulfide, Triethylenethiophosphorotriamide, Tris(ethylenimino)thiophosphate, CBC 806495, Phosphorothioic acid triethylenetriamide, Tris(aziridinyl)phosphine sulfide, Phosphine sulfide, tris(1-aziridinyl)-, Tri(ethyleneimino)thiophosphoramide, Aziridine, 1,1',1''-phosphinothioylidynetris-, NCI-C01649, NSC 6396, NSC-6396, N,N',N''-Triethylenethiophosphamide, SK 6882, Thiotepum [INN-Latin], Tiotepa [INN-Spanish], Tri-1-aziridinylphosphine sulfide, Tris(1-aziridinyl)phosphine sulphide, UNII-905Z5W3GKH, Phosphoric tri(ethyleneamide), C6H12N3PS, CCRIS 586, N,N',N''-Triethylenethiophosphortriamide, AI3-24916, HSDB 3258, NSC6396, 1,1',1''-Phosphinothioylidynetrisaziridine, N,N',N''-Triethylenephosphorothioic triamide, N,N',N''-Tri-1,2-ethanediylthiophosphoramide, EINECS 200-135-7, Thiophosphoramide, N,N',N''-tri-1,2-ethanediyl-, BRN 0145978, N,N',N''-Tri-1,2-ethanediylphosphorothioic triamide, WR-45312, MLS001333083, MLS003389372, 905Z5W3GKH, CHEBI:9570, Phosphorothioic triamide, N,N',N''-tri-1,2-ethanediyl-, AI 3-24916, FOCVUCIESVLUNU-UHFFFAOYSA-N, Phosphorothioic triamide, N,N',N''-triethylene-, NCGC00095042-04, NCGC00095042-06, DSSTox_CID_1339, tris(aziridin-1-yl)-thioxo-$l^{5}-phosphane, Tris(aziridinyl)-phosphine sulfide (thio-tepa), DSSTox_RID_76093, DSSTox_GSID_21339, AZIRIDINE,1,1',1''-PHOSPHINOTHIOYLIDYNETRIS-, Thiotepum, Tiotepa, CAS-52-24-4, SMR000058542, tris(aziridin-1-yl)-sulfanylidene-, SR-05000001855, Thiotepa [USP:INN:BAN:JAN], Thiotepa [USAN:INN:BAN:JAN], N,N',N"-Triethylenethiophosphamide, Tepadina (TN), Thioplex (TN), N,N',N"-Triethylenethiophosphoramide, Spectrum_001689, Thiophosphoramide, N,N',N"-triethylene-, WR 45312, Thiophosphoramide, N,N',N''-triethylene-, AC1L1KDQ, Spectrum2_001557, Spectrum3_001594, Spectrum4_000208, Spectrum5_001641, Aziridine, 1,1,1"-phosphinothioylidynetris-, CHEMBL671, D00YZA, Thioplex (TN) (Immunex), SCHEMBL4760, Phosphorothioic triamide, N,N',N"-triethylene-, Thiotepa (JAN/USP/INN), Triethylenethiop hosphoramide, Thio-TEPA, 98%, solid, BSPBio_003188, KBioGR_000815, KBioSS_002169, triethylenethiophosphortriamide, 4-20-00-00052 (Beilstein Handbook Reference), KSC917M9N, MLS001333084, MLS002207150, MLS006009972, ARONIS24177, BIDD:GT0127, DivK1c_000817, SPECTRUM1503324, SPBio_001434, GTPL7622, DTXSID0021339, CTK8B7696, HMS502I19, KBio1_000817, KBio2_002169, KBio2_004737, KBio2_007305, KBio3_002688, N,N''-Triethylenethiophosphamide, THIOPHOSPHRAMIDE,THIO-TEPA, AOB5373, 1,1,1-phosphorothioyltriaziridine, MolPort-001-783-551, NINDS_000817, HMS1922A14, HMS2093E05, HMS2232P17, HMS3372D10, N,N''-Triethylenethiophosphoramide, Pharmakon1600-01503324, BCP04110, KS-000010LT, ZINC1530867, Tox21_111399, Tox21_400065, ANW-58232, BDBM50418086, CCG-39776, LS-170, MFCD00145452, NSC758455, RW2156, AKOS005267118, CS-3119, DB04572, GC10080, MCULE-5478761622, NSC-758455, RL03925, RTR-018556, 1,1''-Phosphinothioylidynetrisaziridine, IDI1_000817, Thiophosphoramide,N',N'' -triethylene-, NCGC00095042-01, NCGC00095042-02, NCGC00095042-03, NCGC00095042-05, NCGC00095042-07, NCGC00095042-08, NCGC00095042-09, PHOSPHOROTHIOIC TRI(ETHYLENEAMIDE), AN-41625, AS-16885, HY-17574, KB-81272, N,N''-Triethylenephosphorothioic triamide, NCI60_013117, SC-27282, SBI-0051814.P002, tris(1-aziridinyl)-sulfanylidenephosphorane, tris(aziridin-1-yl)-lambda-phosphanethione, AB0006704, AB2000286, Aziridine,1',1''-phosphinothioylidynetris-, N,N''-Tri-1,2-ethanediylthiophosphoramide, Phosphorothioic triamide,N',N''-triethylene, Thiophosphoramide, N,N',N'' -triethylene-, TR-018556, tris(aziridin-1-yl)-lambda5-phosphanethione, Aziridine,1,1',1'-phosphinothioylidynetris-, FT-0082517, FT-0600281, tris(aziridin-1-yl)-$l;{5}-phosphanethione, tris(aziridin-1-yl)-sulfanylidenephosphorane, WLN: T3NTJ APS&- AT3NTJ&- AT3NTJ, Y0223, 1-[Di(1-aziridinyl)phosphorothioyl]aziridine #, C07641, D00583, Phosphorothioic triamide, N,N',N''-triethylene, Thiophosphoramide,N',N''-tri-1,2-ethanediyl-, Z-0841, 24126-EP2272827A1, 24126-EP2272832A1, 24126-EP2275420A1, 24126-EP2280012A2, 24126-EP2292615A1, 24126-EP2295055A2, 24126-EP2295416A2, 24126-EP2295426A1, 24126-EP2295427A1, 24126-EP2298748A2, 24126-EP2298764A1, 24126-EP2298765A1, 24126-EP2298768A1, 24126-EP2298778A1, 24126-EP2301928A1, 24126-EP2305642A2, 24126-EP2308833A2, 24126-EP2311453A1, 24126-EP2314590A1, AB00052346-06, AB00052346_07, N,N',N''-Tri-1,2-et hanediylthiophosphoramide, 145T452, A828998, N,N''-Tri-1,2-ethanediylphosphorothioic triamide, 1-(DI(1-AZIRIDINYL)PHOSPHOROTHIOYL)AZIRIDINE, I09-1625, Q-201826, SR-05000001855-1, SR-05000001855-5, tris(aziridin-1-yl)-sulfanylidene-$l^{5}-phosphane, BRD-K09631521-001-05-7, Phosphorothioic triamide,N',N''-tri-1,2-ethanediyl-, TRIS(AZIRIDIN-1-YL)-LAMBDA(5)-PHOSPHANETHIONE, Tiofosyl;Tiofosfamid;Triethylenethiophosphoramide;Thioplex, Z2574360269, Thiotepa, United States Pharmacopeia (USP) Reference Standard, 1631739-26-8, 639-23-6, 85177-92-0

ID: 620

InChIKey: FOGDPGQSHLLYIK-XYQGXRRISA-N
SMILES: C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 64740
synonyms found at PubChem are:
Spectinomycin dihydrochloride, 21736-83-4, actinospectacin, Spectinomycin hydrochloride, Spectinomycin HCl, Spectinomycin (dihydrochloride), Spectinomycin dihydrochloride pentahydrate, CHEBI:9216, Spectinomycin hydrochloride anhydrous, EN300-74585, DSSTox_CID_25429, DSSTox_RID_80873, DSSTox_GSID_45429, 22189-32-8, UNII-296JEI210Z, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-benzo[b]pyrano[2,3-e][1,4]dioxin-4-one dihydrochloride, Spectinomycin hydrochloride hydrate, 296JEI210Z, (+)-Spectinomycin Dihydrochloride, SR-05000001868, Spectinomycin 2HCl, Prestwick_106, NCGC00016754-01, CAS-21736-83-4, SCHEMBL184452, SPECTRUM1500538, AC1L21U2, CHEMBL3184600, DTXSID9045429, FOGDPGQSHLLYIK-XYQGXRRISA-N, MolPort-003-666-283, HMS1570B09, HMS1920P22, HY-B0438, Tox21_110592, CCG-39253, s2510, AKOS016010051, Tox21_110592_1, API0004215, CS-2544, NE47662, NCGC00017354-07, AK115166, CC-34517, AB2000613, AX8151790, S0584, ST24049298, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one Hydrochloride, C11619, C-21807, SR-05000001868-3, SR-05000001868-5, W-107526, Spectinomycin hydrochloride, Antibiotic for Culture Media Use Only, (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.0?,?]tetradecan-7-one dihydrochloride, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one dihydrochloride, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-N,N',2-trimethyl-4-oxodecahydro-2H-pyrano[2,3-b][1,4]benzodioxine-6,8-diaminium dichloride, Spectogard, Stanilo, Spectam Scour Halt, EINECS 244-554-3, Trobicin, 1695-77-8 (Parent), 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, 4H-Pyrano(2,3-b)(1,4)benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride, (2R-(2-alpha,4a-beta,5a-beta,6-beta,7-beta,8-beta,9-alpha,9a-alpha,10a-beta))-, Spectinomycin Hydrochloride (anhydrous), Spectinomycin Dihydrochloride, Anhydrous, NSC 248616, AC1MHWL1, LS-127328, Spectinomycin hydrochloride

ID: 621

InChIKey: FOIVPCKZDPCJJY-JQIJEIRASA-N
SMILES: C/C(=C\C1=CC=C(C=C1)C(=O)O)/C2=CC3=C(C=C2)C(CCC3(C)C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5289501
synonyms found at PubChem are:
TTNPB, Arotinoid acid, 71441-28-6, Arotinoic acid, Ro 13-7410, CCRIS 3297, AGN 191183, UNII-673M8C29UR, 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid, Tocris-0761, Lopac-T-3757, AGN-191183, BRN 2008247, CHEMBL275311, CHEBI:75261, 673M8C29UR, 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid, (E)-4-(2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl)benzoic acid, p-((E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl)benzoic acid, 4-(2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthenyl)-1E-propen-1-yl)benzoic acid, 4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid, (E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl)benzoic acid, 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID, Benzoic acid, 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)-, (E)-, SR-01000076154, arotinoid Ro-137410, 1xap, 4-[2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHENYL)-1E-PROPEN-1-YL]BENZOIC ACID, Ttnpb(arotinoid acid), AC1NRDEA, Spectrum5_001943, TTNPB (Arotinoid Acid), D0G6JM, DSSTox_CID_20743, DSSTox_GSID_40743, Lopac0_001176, BSPBio_001532, MLS002153338, SCHEMBL177444, T3757_SIGMA, BML2-E10, GTPL2646, DTXSID6040743, 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid, FOIVPCKZDPCJJY-JQIJEIRASA-N, MolPort-003-959-717, HMS1361M14, HMS1791M14, HMS1989M14, HMS2232G03, HMS3263L13, HMS3402M14, Benzoic acid,4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-, ZINC4475360, Tox21_304044, Tox21_501176, BDBM50032219, MFCD00673917, s4627, AKOS024458636, CCG-205250, CS-3253, DB02877, LP01176, Ro-137410, (e)-4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid, (e)-4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1-propenyl) benzoic acid, IDI1_034002, NCGC00016015-01, NCGC00016015-02, NCGC00016015-03, NCGC00016015-04, NCGC00016015-05, NCGC00016015-06, NCGC00016015-07, NCGC00016015-08, NCGC00016015-09, NCGC00016015-10, NCGC00024775-01, NCGC00024775-02, NCGC00024775-03, NCGC00024775-04, NCGC00024775-05, NCGC00024775-06, NCGC00024775-07, NCGC00024775-08, NCGC00261861-01, NCGC00357251-01, BC251620, HY-15682, LS-38311, SMR001230750, CAS-71441-28-6, EU-0101176, Ro 13-7410;Arotinoid acid;AGN191183, X6862, C15634, T 3757, 102723-EP2272841A1, 102723-EP2301936A1, 102724-EP2272841A1, 102724-EP2301936A1, SR-01000076154-1, SR-01000076154-3, SR-01000076154-5, BRD-K49685476-001-02-7, BRD-K49685476-001-05-0, (e)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid, 4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid, p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-benzoic acid, (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1 -propenyl] benzoic acid, 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid, 4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid

ID: 622

InChIKey: FOJWIEHQODXJCL-UHFFFAOYSA-N
SMILES: C(C1=C(SCC(=O)OC)C=CS1)1C(C(=O)OCC2=CC=CC=C2)=C(C)NC(C)=C1C(=O)OCC1=CC=CC=C1

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Fossa" "M Zacchigna" "LJ Galietta" "F Cateni" "M Giampieri" "MT Mazzei" "N Pedemonte" "M Mazzei"

CID is 46196543

ID: 623

InChIKey: FOWAIJYHRWFTHR-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)Cl)N=C(N)N=C(N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16444
synonyms found at PubChem are:
1-(3-Chlorophenyl)biguanide hydrochloride, 2113-05-5, m-chlorophenylbiguanide hydrochloride, 1-(m-Chlorophenyl)-biguanide hydrochloride, m-CPBG hydrochloride, 1-(3-CHLOROPHENYL)BIGUANIDE HCL, 1-(m-Chlorophenyl)biguanide hydrochloride, 1-carbamimidamido-N-(3-chlorophenyl)methanimidamide hydrochloride, Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, monohydrochloride, N-m-Chlorophenylbiguanide hydrochloride, SR-01000075547, BIGUANIDE, 1-(m-CHLOROPHENYL)-, MONOHYDROCHLORIDE, N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride, N-(3-Chlorophenyl)-imidodicarbonimidic diamide monohydrochloride, ACMC-20apbq, AC1MBRPQ, EU-0100343, MLS001056739, SCHEMBL1320574, CHEMBL1256027, CTK1A2803, KS-00000LTE, DTXSID80175361, MolPort-001-756-912, ZX-AT005881, Tox21_500343, BN0321, MFCD00053019, NSC210906, OR0928, SBB100366, AKOS023093273, CCG-221647, LP00343, MCULE-2237141498, NSC-210906, PS-7507, VZ20899, KS-00003R36, NCGC00093781-01, NCGC00261028-01, KB-17058, SMR000326726, TC-172493, B6306, C-144, FT-0634040, ST50825927, K-0005, 1-(3-Chlorophenyl)biguanide hydrochloride, solid, C-15185, J-013867, SR-01000075547-1, SR-01000075547-3, {[(3-Chloroanilino)(imino)methyl]amino}methanimidamide hydrochloride, 2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine hydrochloride, amino{[(3-chlorophenyl)amino]iminomethyl}carboxamidine, chloride, Imidodicarbonimidicdiamide, N-(3-chlorophenyl)-, hydrochloride (1:1), NSC 210906, AI3-60023, 48144-44-1 (Parent), Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, monohydrochloride (9CI), C8H10ClN5.HCl, LS-43875

ID: 624

InChIKey: FPHMSKWSSWNMQV-UHFFFAOYSA-M
SMILES: CC1=CC(=CN2C1=NC3=[N+](C2)C=C(C=C3C)Br)Br.[I-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 10696617

ID: 625

InChIKey: FPLMIPQZHHQWHN-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281699
synonyms found at PubChem are:
Tamarixetin, 603-61-2, 4'-Methoxyquercetin, 4'-O-Methylquercetin, Quercetin 4'-methyl ether, UNII-73WRA8Z8M8, 3,3',5,7-Tetrahydroxy-4'-methoxyflavone, 4'-O-Methyl Quercetin, Quercetin-4'-methylether, 73WRA8Z8M8, CHEMBL226034, CHEBI:67492, 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one, 4'-Methoxy-3,3',5,7-tetrahydroxyflavone, Tamaraxetin, 3-O-rhamnopyranosyl-1-2-glucopyranoside, 3-O-alpha-L-rhamnopyranosyl-1-2-beta-D-glucopyranoside, AC1NQYX7, D06PZE, C10188, SCHEMBL892776, DTXSID00209056, FPLMIPQZHHQWHN-UHFFFAOYSA-N, MolPort-001-741-910, ZINC6484604, BDBM50325674, LMPK12110606, AKOS024287252, MCULE-8124433804, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)- (9CI), 4'-methoxy-3,5,7,3'-tetrahydroflavone, CC-34633, FT-0603487, W2755, C-19473, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-chromen-4-one, 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-

ID: 626

InChIKey: FPOQLQZHRCEVOT-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CC(=O)NO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 220184
synonyms found at PubChem are:
N-HYDROXY-2-PHENYLACETAMIDE, N-Hydroxy-2-phenyl-acetamide, PHENYLACETOHYDROXAMIC ACID, 5330-97-2, CHEMBL152665, FPOQLQZHRCEVOT-UHFFFAOYSA-N, 2-phenylethanehydroxamic acid, NSC2544, benzylhydroxamic acid, n-hydroxyphenylacetamide, AC1Q5QCW, Spectrum2_001716, Spectrum3_001684, N-hydroxy-phenyl-acetamide, AC1L58DD, BSPBio_003208, SPECTRUM210031, SCHEMBL213873, SPBio_001732, CHEBI:93303, CTK1H4422, KBio3_002428, DTXSID80277490, MolPort-002-479-420, HMS1923A21, NSC-2544, BDBM50015094, CCG-39445, SBB086771, ZINC16887669, AKOS000184738, MCULE-5154879216, NCGC00095226-01, NCGC00095226-02, NCGC00095226-03, NCGC00095226-04, KB-58301, FT-0693745, ST51029581, 330H972, AD-266/40386900, BRD-K74112339-001-02-7, BRD-K74112339-001-03-5

ID: 627

InChIKey: FQEQMASDZFXSJI-BPCQOVAHSA-N
SMILES: C1CCN2CC3CC([C@@H]2C1)CN4C3=CC=CC4=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 228640
synonyms found at PubChem are:
Thermopsine, Rhombinin, NSC21725, AC1L5GDH, AC1Q6APS, Spectrum2_001627, Spectrum4_001842, Spectrum5_000344, KBioGR_002244, THERMOPSINE PERCHLORATE, SPBio_001693, SDCCGMLS-0066774.P001

ID: 628

InChIKey: FQPFAHBPWDRTLU-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC=N2.CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 9433
synonyms found at PubChem are:
aminophylline, 317-34-0, Aminophyllin, Theophyllamine, Cardophyllin, Phyllocontin, Somophyllin, Truphylline, Theophylline ethylenediamine, Cardiofilina, Ethophylline, Metaphylline, Methophylline, Peterphyllin, Syntophyllin, Theophyldine, Theophyllaminum, Variaphylline, Aminocardol, Ammophyllin, Cardiomin, Cardophylin, Cariomin, Diaphylline, Diophllin, Diuxanthine, Eurphyllin, Euufillin, Genophyllin, Grifomin, Inophylline, Linampheta, Lixaminol, Metaphyllin, Minaphil, Miofilin, Neophyiline, Norofilina, Phylcardin, Phyllindon, Stenovasan, Theodrox, Theolamine, Theolone, Thephyldine, Vasofilina, Aminodur, Carena, Lasodex, Somophyllin O, Aminophylline Dye Free, Euphylline, Euphyllin, Diaphilline, Euphyllinum, Diophyllin, DOBO, Euufilin, Theomin, Rectalad aminophylline, Rectalad-aminophylline, Theophyllaminium, Theophyllin aethylendiamin, Aminodur dura-tabs, Theophyline ethylenediamine, Theophyllin ethylenediamine, Eufilina [Polish], Eufilina, Aminophylline ethylenediamine, Aminofillina [DCIT], Etilen-xantisan tabl., Aminofilina [Spanish], Dura-Tab S.M. Aminophylline, Aminophylline Anhydrous, Somopphyllin, Dura-tab sm aminophylline, Aminofilina [INN-Spanish], Aminophyllinum [INN-Latin], Aminofilina, Aminofillina, Diaphyllin, Mudrane GG Tablets, Phyllotemp, UNII-27Y3KJK423, HSDB 221, Theophyllinum et ethylendiaminum, Theophylline compound with ethylenediamine, Mudrane GG-2 Tablets, Theophyllin aethylendiamin [German], NSC 7919, EINECS 206-264-5, TH/100, Aminophylline dihydrate, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1), BY 108, AMINOPHYLLINE IN SODIUM CHLORIDE 0.45%, Theophylline, compd with ethylenediamine (2:1), 27Y3KJK423, Ethylenediamine, compd. with theophylline (1:2), Theophylline compound with ethylenediamine (2:1), Theophylline, compd. with ethylenediamine (2:1), Somophyllin-O, 1,3-dimethyl-7H-purine-2,6-dione; ethane-1,2-diamine, AMINOPHYLLINE IN SODIUM CHLORIDE 0.45% IN PLASTIC CONTAINER, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd with 1,2-ethanediamine (2:1), 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione compd. with 1,2-ethanediamine (2:1), Aminophyllinum, Euphyllin Retard, Theophylline-Ethylenediamine Anhydrous, C7H8N4O2, Mundiphyllin Retard, Pulmophyllin (new), Pulmophylline (new), 95646-60-9, 1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine, Aminocadol, A 1755, Aminophylline [INN:BAN:JAN], Prestwick_93, Somophyllin (TN), Phyllocontin-350, Aminophylline [USP:INN:BAN:JAN], C16H24N10O4, Etilen-xantisan tabl, Ammonium Carbonate NF, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, cmpd. with 1,2-ethanediamine (2:1), Lopac-A-1755, Aminophylline (USP/INN), Aminophylline (Truphylline), SCHEMBL5037, Aminophylline Anhydrous Powder, AC1L1T14, CHEBI:2659, Aminophylline, >=98%, powder, CHEMBL1370561, bis(constant-T); ethylenediamine, ethylenediamine; bis(theophylline), FQPFAHBPWDRTLU-UHFFFAOYSA-N, MolPort-004-959-540, MolPort-006-069-308, Theophylline ethylenediamine (TN), (Theophylline)2 . Ethylenediamine, HMS1570D21, HMS2097D21, HMS3260C09, HMS3655A19, HMS3714D21, BCP23387, HY-B0140, Tox21_500014, MFCD00013221, AKOS015951253, AKOS015960458, Aminophylline, anhydrous, 98% 25g, BCP9000293, CCG-220820, CCG-221318, CS-1936, DB01223, KS-5340, LP00014, Aminophylline(Phyllocontin, Truphylline), NCGC00016113-01, NCGC00016113-02, NCGC00016113-03, NCGC00093539-01, NCGC00260699-01, AC-11138, AN-44247, CAS-317-34-0, Theophylline hemi(ethylenediamine) complex, BCP0726000247, AB1009250, LS-149548, A2805, EU-0100014, FT-0622295, ST50298827, D00227, SR-01000872628, SR-01000872628-1, W-106881, 1,3-dimethyl-1H-purine-2,6(3H,7H)-dione compound with ethane-1,2-diamine (2:1), 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione compound with ethane-1,2-diamine (2:1), 1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione compound with ethane-1,2-diamine (2:1), 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1), 1,3-dimethyl-1,3-dihydropurine-2,6-dione, 1,3-dimethyl-1,3-dihydropurine-2,6-d ione, ethane-1,2-diamine, 12767-26-9, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1), mixt. with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione, 442519-87-1, 8013-40-9, 80186-94-3

ID: 629

InChIKey: FQRUARKLFVTIIK-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC=C(C=C3)F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 10378415
synonyms found at PubChem are:
CHEMBL344504, 2-(4-fluorophenyl)-7-methoxy-4H-chromen-4-one, D0G6MA, 4'-Fluoro-7-methoxyflavone, SCHEMBL9142214, BDBM50310198, ZINC27557271, 2-(4-Fluoro-phenyl)-7-methoxy-chromen-4-one

ID: 630

InChIKey: FQTXPVLCCDQRHY-UHFFFAOYSA-N
SMILES: CC(C1=C(C(=CC=C1)Cl)Cl)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957540
synonyms found at PubChem are:
39959-66-5, 1-(2,3-Dichlorophenyl)ethanamine hydrochloride, LY 78335, (+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride, EU-0100476, SCHEMBL1321451, CHEMBL1255749, CTK8F1484, KS-00000TZV, DTXSID80474684, DCMB hydrochloride; LY-78335, MolPort-003-940-937, Tox21_500476, 1-(2,3-dichlorophenyl)ethanamine hcl, AKOS024457957, CCG-221780, LP00476, ACM39959665, NCGC00093885-01, NCGC00093885-02, NCGC00261161-01, DS-19653, D-103, 2,3-Dichloro-?-methylbenzylamine hydrochloride, SR-01000075609, SR-01000075609-1, (?)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride, (y)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride, ( inverted question mark)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride

ID: 631

InChIKey: FQWLMRXWKZGLFI-BQYFGGCBSA-N
SMILES: C1=CC(=CC=C1/C=C/C2=CC(=CC3=C2[C@@H]([C@H](O3)C4=CC=C(C=C4)O)C5=CC(=CC(=C5)O)O)O)O

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"H Yang" "B Yu" "T Ma" "Y Sui" "Y Zhang" "X Gao"

CID is 5315233
synonyms found at PubChem are:
(+)-epsilon-Viniferin, Trans-E-Viniferin, UNII-0AF07924BM, CHEBI:76137, 0AF07924BM, trans-epsilon-Viniferin, Viniferin, 129170-22-5, 5-[(2S,3S)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol, 5-{(2S,3S)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol, AC1NSSU1, (+)-trans-epsilon-viniferin, CHEMBL498439, SCHEMBL13004136, 253435-07-3, ZINC5722187, 1,3-Benzenediol, 5-((2S,3S)-2,3-dihydro-6-hydroxy-2-(4-hydroxyphenyl)-4-((1E)-2-(4-hydroxyphenyl)ethenyl)-3-benzofuranyl)-

ID: 632

InChIKey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
SMILES: CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2733525
synonyms found at PubChem are:
Tamoxifen citrate, 54965-24-1, Istubal, Tamoxifen (Citrate), Zitazonium, UNII-7FRV7310N6, I.C.I. 46474 citrate, Tamoxifen citrate salt, ICI 46474, Farmifeno, Ginarsan, Jenoxifen, Ledertam, Nourytan, Noxitem, Oncotam, Tafoxen, Tamofen, Tamoplex, Tamoxasta, Tamoxifen Citrate (Nolvadex), Terimon, Zynoplex, Emblon, Nolgen, Noltam, Zemide, Genox, Tamax, Taxus, Tamox-Puren, 7FRV7310N6, Z-Tamoxifen citrate, NSC180973, NCGC00024928-06, CAS-54965-24-1, DSSTox_CID_1301, N,N-Dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)ethylamine citrate, DSSTox_RID_76068, Ethylamine, 2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, citrate (Z)-, DSSTox_GSID_21301, CCRIS 6718, Caditam, EINECS 259-415-2, ICI 46,474, 7244-97-5, Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate, SMR000677949, SR-01000075523, citro; tamoxifen, trans-1-(p-beta-Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate, (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine citrate (1:1), 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid, Prestwick_458, Tamoxifen citrate [USAN:USP:JAN], Tamoxifen (Nolvadex), Tamoxifen Citrate,(S), Tamoxifen, citrate salt, AC1MBZ3O, Lopac-T-9262, CHEMBL786, SCHEMBL6365, MLS001055370, MLS002154210, ARONIS23853, SPECTRUM1500557, Nolvadex (TN) (AstraZeneca), DTXSID8021301, Tamoxifen citrate (JP17/USP), HMS500M20, Tamoxifen citrate salt, >=99%, FQZYTYWMLGAPFJ-OQKDUQJOSA-N, HMS1568M14, HMS1921C13, HMS2092K17, HMS2095M14, HMS2232E08, HMS3263B08, HMS3712M14, Pharmakon1600-01500557, (2-{4-[1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine; 2-hydroxypropane-1,2,3-tricarboxylic acid, (Z)-(2-(4-(1,2-Diphenylbut-1-enyl)phenoxy)ethyl)dimethylammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate, 10540-29-1 (Parent), 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt), Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), hydroxypropane-1,2,3-tricarboxylate, Tox21_110938, Tox21_202070, Tox21_300274, Tox21_501203, CCG-39629, MFCD00058321, NSC757345, s1238, s1972, SBB080554, AKOS005111126, Tox21_110938_1, CS-1852, KS-5046, LP01203, NSC-180973, NSC-757345, NCGC00016206-01, NCGC00016206-02, NCGC00016206-03, NCGC00016206-04, NCGC00016206-05, NCGC00016206-06, NCGC00024928-02, NCGC00024928-23, NCGC00094450-01, NCGC00094450-02, NCGC00094450-03, NCGC00094450-04, NCGC00254000-01, NCGC00259619-01, NCGC00261888-01, CPD000677949, HY-13757, KB-80806, LS-68202, M936, SAM002564256, SC-13399, BCP0726000223, AB0006810, AB2000015, EU-0101203, (Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy), D00966, J10303, K-9859, T 9262, 965T241, Q-201776, SR-01000075523-1, SR-01000075523-3, SR-01000075523-5, SR-01000075523-6, SR-01000075523-10, (Z)-1-(4-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene Citrate, Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard, (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate, Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard, (Z)-2-[ p-(1,2-Diphenyl-1-butenyl)phenoxy]- N, N-dimethylethylamine citrate (1:1), (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-ethanamine cirtrate (1:1), Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard, (Z)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate, (Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate, {2-[4-((1Z)-1,2-diphenylbut-1-enyl)phenoxy]ethyl}dimethylamine, 2-hydroxypropa ne-1,2,3-tricarboxylic acid, 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine; 2-hydroxypropane-1,2,3-tricarboxylic acid, Ethanamine, 2-(4-((1Z)-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Ethanamine,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Tamoxan, Tamoxene, Tamoxin, Tamox, 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate

ID: 633

InChIKey: FRCCEHPWNOQAEU-UHFFFAOYSA-N
SMILES: C1=CC(C2C1C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3589
synonyms found at PubChem are:
heptachlor, Heptachlorane, Heptamul, 3-Chlorochlordene, Rhodiachlor, Aahepta, Agroceres, Heptagran, Hepta, 76-44-8, Velsicol heptachlor, GPKh, Technical heptachlor, Eptacloro, Heptachloor, Heptachlore, Heptox, Velsicol 104, Arbinex 30TN, Heptagranox, Basaklor, Heptamak, Heptasol, Soleptax, Rcra waste number P059, NCI-C00180, Eptacloro [Italian], Heptachloor [Dutch], Heptachlore [French], Caswell No. 474, Latka 104, ENT 15,152, Heptachlor [BSI:ISO], Heptachlorotetrahydro-4,7-methanoindene, Latka 104 [Czech], H-34, Heptachlore [ISO-French], NSC 8930, Gold Crest H-60, Termide, Heptachlor (technical grade), CCRIS 324, 4,7-Methano-1H-indene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-, E 3314, HSDB 554, Drinox H-34, H-60, OMS 193, 3,4,5,6,7,8,8a-Heptachlorodicyclopentadiene, EINECS 200-962-3, Heptachlor and metabolites, RCRA waste no. P059, EPA Pesticide Chemical Code 044801, Dicyclopentadiene, 3,4,5,6,7,8,8a-heptachloro-, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene, AI3-15152, CHEBI:34785, 1,4,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-methyleneindene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-1H-4,7-methanoindene, 1,4,5,6,7,8,8a-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane, 4,7-Methanoindene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-, 1(3a),4,5,6,7,8,8-Heptachloro-3a(1),4,7,7a-tetrahydro-4,7-methanoindene, alpha-Dicyclopentadiene, 3,4,5,6,7,8,8A-heptachloro-, 1,4,5,6,7,8,8-Heptachlorotetrahydro-4,7-methanoindene, DSSTox_CID_679, 1,4,5,6,7,8,8-Eptacloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indene, 1,4,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-endomethyleneindene, 1,4,5,6,7,8,8-Heptachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indeen, 1,4,5,6,7,8,8-Heptachlor-3a,4,7,7,7a-tetrahydro-4,7-endo-methano-inden, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-endomethanoindene, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanol-1H-indene, 1,4,5,6,7,8,8-Eptacloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indene [Italian], 1,4,5,6,7,8,8-Heptachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indeen [Dutch], 1,4,5,6,7,8,8-Heptachlor-3a,4,7,7,7a-tetrahydro-4,7-endo-methano-inden [German], DSSTox_RID_75727, DSSTox_GSID_20679, heptaklor, 1,5,7,8,9,10,10-heptachlorotricyclo[5.2.1.0(2,6)]deca-3,8-diene, CAS-76-44-8, Tetrahydro, hepta klor, Spectrum_001951, SpecPlus_000590, AC1Q3LFN, Spectrum2_001891, Spectrum3_000865, Spectrum4_000705, Spectrum5_002052, AC1L1G9N, AC1Q3HE4, SCHEMBL65124, BSPBio_002509, KBioGR_001229, KBioSS_002505, SPECTRUM330078, MLS002454407, DivK1c_006686, SPBio_001822, CHEMBL194400, DTXSID3020679, KBio1_001630, KBio2_002497, KBio2_005065, KBio2_007633, KBio3_002009, NSC8930, FRCCEHPWNOQAEU-UHFFFAOYSA-N, NSC-8930, Tox21_201911, Tox21_300534, BDBM50410521, CCG-39341, LS-1694, NCGC00091514-01, NCGC00094549-01, NCGC00094549-02, NCGC00094549-03, NCGC00094549-04, NCGC00094549-05, NCGC00254523-01, NCGC00259460-01, SMR001372010, 3,5,6,7,8,8-Heptachlorodicyclopentadiene, C14185, Dicyclopentadiene,4,5,6,7,8,8a-heptachloro-, WLN: L C555 A DU IUTJ AG AG BG FG HG IG JG, 4, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-, 1,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, 3a,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, 1(3a),5,6,7,8,8-Heptachloro-3a(1),4,7,7a-tetrahydro-4,7-methanoindene, 1,4,5,6,7,10,10-hept achloro-4,7,8,9-tetrahydro-4,7-methyleneindene, 1,4,5,6,7,8,8-h eptachloro-3a,4,7,7a-tetrahydro-4,7-endomethanoindene, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7,7a-tetrahydro-4,7-methylene indene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7,7a-tetrahydro-4,7-methyleneindene, 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-endo-methanoindene, 1,4,5,6,7,8,8a-heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, 1,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-endo-methyleneindene, 1,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-methyleneindene, 1,5,6,7,8,8-Eptacloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indene, 1,5,6,7,8,8-Heptachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indeen, 1,5,6,7,8,8-Heptachlor-3a,4,7,7,7a-tetrahydro-4,7-endo-methano-inden, 1,5,6,7,8,8-Heptachloro-3a,4,7,7,7a-tetrahydro-4,7-methylene indene, 1,5,6,7,8,8-Heptachloro-3a,4,7,7a- tetrahydro-4,7-methanoindene, 1,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-endo-methanoindene, 1H-1,4,5, 6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, 1H-1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene, (4S,7S)-1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-1H-4,7-methanoindene, 1,4,5,6,7,10,10-Heptachloro-4,7,8,9-tetrahydro-4,7-endo-methyleneindene, Indene, 1,4,5,6,7,8,8-heptachloro-3alpha,4,7,7alpha-tetrahydro-4,7-methano-, 23720-59-4, 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-3-methyl-4,7-Methano-1H-ind ene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-6,9-methano-2,4,3-benzodioxathiepin, 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-3-methyl-4,7-Methano-1H-indene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-6,9-methano-2,4,3-benzodioxathiepin

ID: 634

InChIKey: FSEUPUDHEBLWJY-HWKANZROSA-N
SMILES: C/C(=N\O)/C(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6409633
synonyms found at PubChem are:
2,3-butanedione monoxime, Diacetyl monoxime, Diacetylmonoxime, Biacetyl monoxime, Biacetyl monooxime, Diacetyl monooxime, Diacetylmonooxime, 2,3-Butanedione 2-oxime, 57-71-6, 2-Oximino-3-butanone, 3-Oximino-2-butanone, 2,3-Butanedione-2-monoxime, DAM (oxime), 2,3-Butanedione, monooxime, 2,3-Butanedione 3-monoxime, 3-oxo-2-butanone oxime, 2,3-Butanedione monooxime, Isonitrosoethyl methyl ketone, (3E)-3-hydroxyiminobutan-2-one, 2,3-Butanedione oxime, UNII-19SQ93LM6H, 3-(hydroxyimino)butan-2-one, C4H7NO2, NSC 116103, CCRIS 6215, CHEBI:4480, EINECS 200-348-5, BRN 0605582, AI3-23962, 19SQ93LM6H, BDM, DAM, (2E)-butane-2,3-dione oxime, CHEMBL1255578, 2, monooxime, NSC-660, 2, monoxime, NSC-116103, WLN: QNUY1&V1, 2,3-Butanedione, 2-oxime, 2,3-Butanedione 2-Monoxime, 17019-25-9, KBDO, SR-01000075306, FSEUPUDHEBLWJY-HWKANZROSA-N, 2,3-BUTANEDIONE-2-OXIME, 2,3-BDMO, potassium 2,3-butanedione monoximate, AC1O4OEO, 2, 3-Butanedione Monoxime, Lopac0_000090, 4-01-00-03646 (Beilstein Handbook Reference), SCHEMBL257234, SCHEMBL282899, NSC660, DTXSID7024669, FSEUPUDHEBLWJY-HWKANZROSA-, (3E)-3-hydroxyimino-2-butanone, 2,3-Butanedione monoxime, 97%, cMAP_000064, MolPort-001-779-942, HMS3260A22, 110828-81-4, 3-[(Z)-Hydroxyimino]-2-butanone, Tox21_500090, 2,3-Butanedione monoxime, >=98%, 2,3-Butanedione, monooxime, (E)-, BDBM50024959, HSCI1_000099, MFCD00002116, NSC116103, ZINC12358749, 2,3-Butanedione, monooxime, (2E)-, AKOS005207181, 2,3-Butanedione, 2-oxime, (2E)-, CCG-204185, LS-1392, NCGC00024887-02, NCGC00024887-03, NCGC00024887-04, NCGC00024887-05, NCGC00260775-01, L027, SC-46911, 2,3-Butanedione monoxime, p.a., 99.0%, EU-0100090, FT-0082821, A feminineOOo poundO>>e inverted question mark, B 0753, C07509, A831569, J-610059, S14-1109, SR-01000075306-1, SR-01000075306-3, W-105446, paragraph signthornOOo poundO>>e inverted question mark, InChI=1/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+, 2,3-Butanedione monoxime, for spectrophotometric det. of urea, >=99.0%

ID: 635

InChIKey: FSKVGWXINKZUKS-UHFFFAOYSA-M
SMILES: C[N+](C)(C)CC=O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2735510
synonyms found at PubChem are:
Betaine aldehyde chloride, 7758-31-8, N,N,N-Trimethyl-2-oxoethanaminium chloride, trimethyl(2-oxoethyl)azanium chloride, (2-Oxoethyl)trimethylammonium chloride, BTL chloride, EU-0100182, AC1MC3H4, MLS002153203, SCHEMBL116970, CHEMBL1256576, DTXSID10370761, MolPort-001-761-299, REGID_for_CID_2735510, HMS2230C14, HMS3260F05, HMS3373H22, Tox21_500182, AKOS027320642, (Formylmethyl)trimethylammonium chloride, CCG-221486, LP00182, KS-0000194S, (formylmethyl)-trimethylammonium chloride, NCGC00093661-01, NCGC00260867-01, SMR000326966, 2-Oxo-N,N,N-trimethylethanaminium chloride, FT-0622916, B 3650, SR-01000075715, Ethanaminium,N,N,N-trimethyl-2-oxo-,chloride(1:1), SR-01000075715-1

ID: 636

InChIKey: FSNITHOUQGJHTR-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(C=C)C2=CC(=O)C(=CC2=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 364106
synonyms found at PubChem are:
4,4'-Dimethoxydalbergione, NSC629751, 2-Methoxy-5-(1-(4-methoxyphenyl)-2-propenyl)benzo-1,4-quinone, Spectrum_000021, SpecPlus_000153, AC1Q6BVY, Spectrum2_000597, Spectrum3_000682, Spectrum5_001863, AC1L7O5Y, BSPBio_002403, KBioSS_000381, SPECTRUM201448, DivK1c_006249, SPBio_000474, CHEMBL1436980, CTK7A2184, KBio1_001193, KBio2_000381, KBio2_002949, KBio2_005517, KBio3_001623, CCG-38518, NSC-629751, NCGC00095719-01, NCGC00095719-02, SR-05000002539, SR-05000002539-1, 2-methoxy-5-[1-(4-methoxyphenyl)allyl]-1,4-benzoquinone, 2-methoxy-5-[1-(4-methoxyphenyl)prop-2-enyl]cyclohexa-2,5-diene-1,4-dione

ID: 637

InChIKey: FSQKKOOTNAMONP-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1981
synonyms found at PubChem are:
acemetacin, 53164-05-9, Rantudil, Emflex, Acemetacinum, Acemix, Acemetacina, Acemetacine, Aximeixin, Rheumibis, Bay f 4975, indomethacin carboxymethyl ester, Solart, Acemetacine [INN-French], Acemetacinum [INN-Latin], Acemetacina [INN-Spanish], TVX 3322, UNII-5V141XK28X, K 708, K-708, TVX 1322, indometacin glycolic ester, EINECS 258-403-4, indomethacin glycolic ester, BRN 0501672, C21H18ClNO6, indometacin carboxymethyl ester, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester, CHEMBL189171, CHEBI:31162, FSQKKOOTNAMONP-UHFFFAOYSA-N, 5V141XK28X, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester, NCGC00016868-09, CAS-53164-05-9, ((1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetoxy)acetic acid, DSSTox_CID_2540, (1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-acetoxy)essigsaeure [German], 2-(2-(1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetoxy)acetic acid, DSSTox_RID_76618, DSSTox_GSID_22540, Rantodil, [1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetoxyacetic Acid, [1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid carboxymethyl ester, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ester with glycolic acid, 1-[p-Chlorobenzoyl]-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester, 2-(2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetoxy)acetic acid, 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid, SMR000058409, SR-01000000070, acemet, acemethacin, acemethazine, Acemetacin [BAN:INN:JAN], Acemetacin [INN:BAN:JAN], {[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetoxy}acetic acid, Rantudil (TN), Prestwick_669, Acemetacin (Emflex), Spectrum_000428, AC1L1CNQ, Prestwick0_000296, Prestwick1_000296, Prestwick2_000296, Prestwick3_000296, Spectrum2_001162, Spectrum3_001868, Spectrum4_000803, Spectrum5_001385, Acemetacin (JP17/INN), {2-[1-(4-chlorbenzoyl)-5-methoxy-2-methyl-1h-indol-3-yl]acetoxy}essigs, AC1Q3N7Y, Bay-f-4975, SCHEMBL23843, BSPBio_000232, BSPBio_003316, KBioGR_001285, KBioSS_000908, 5-22-05-00241 (Beilstein Handbook Reference), MLS000028440, MLS006010622, DivK1c_000490, SPECTRUM1500666, SPBio_001143, SPBio_002451, Acemetacin, analytical standard, BPBio1_000256, DTXSID7022540, CTK8B3535, HMS501I12, KBio1_000490, KBio2_000908, KBio2_003476, KBio2_006044, KBio3_002818, KS-00000FKT, MolPort-002-045-405, NINDS_000490, HMS1568L14, HMS1921A08, HMS2090E21, HMS2095L14, HMS2230G08, HMS3372K20, HMS3656E22, HMS3712L14, Pharmakon1600-01500666, ZINC601272, BCP13127, HY-B0482, TVX-1322, Tox21_113473, (1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-acetoxy)essigsaeure, ANW-42684, BDBM50336272, CCG-39550, MFCD00151473, NSC757413, s2602, AKOS015895194, Tox21_113473_1, AB03974, API0001356, CS-2597, DB13783, MCULE-3371205328, NSC-757413, TV-1322, IDI1_000490, NCGC00016868-01, NCGC00016868-02, NCGC00016868-03, NCGC00016868-04, NCGC00016868-05, NCGC00016868-06, NCGC00016868-07, NCGC00016868-08, NCGC00016868-11, NCGC00016868-12, NCGC00022084-03, NCGC00022084-04, NCGC00022084-05, NCGC00022084-06, NCGC00022084-07, AN-25630, CC-23639, LS-82122, SC-66348, SBI-0051585.P002, AB2000691, A2452, AB00052149, FT-0630659, ST50993919, D01582, AB00052149-15, AB00052149_16, AB00052149_17, 164A059, C-21993, I06-0330, SR-01000000070-2, SR-01000000070-3, BRD-K67563174-001-05-1, BRD-K67563174-001-09-3, 1-[P-CHLOROBENZOYL]-5-METHOXY-2-METHYLINDOLE-3-ACE, Acemetacin, European Pharmacopoeia (EP) Reference Standard, [1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetoxy]-acetic acid, ({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl}oxy)acetic acid, [({1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetyl)oxy]acetic acid, {2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid, 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic Acid Carboxymethyl Ester, 1-[p-Chlorobenzoyl]-5-methoxy- 2-methylindole-3-acetic acid carboxymethyl ester, 1H-Indole-3-aceticacid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester, 2-(2-(1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl)acetyloxy)acetic acid, 2-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetyloxy)acet ic acid, 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetyl]oxyacetic acid, [({1-[(4-chlorophenyl)carbonyl]-2-methyl-5-(methyloxy)-1H-indol-3-yl}acetyl)oxy]acetic acid

ID: 638

InChIKey: FSVJFNAIGNNGKK-UHFFFAOYSA-N
SMILES: C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4891
synonyms found at PubChem are:
praziquantel, 55268-74-1, Droncit, Biltricide, Pyquiton, Cesol, Azinox, Embay 8440, Cutter Tape Tabs, Prasiquantel, Praziquantelum, Traziquantel, Biliricide, Cysticide, Distocide, Drontsit, Prazinon, Praziquantelum [INN-Latin], Cutter, Biltricide (TN), 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one, CCRIS 4114, MLS000038419, Praziquantel [USAN:INN:BAN:JAN], EINECS 259-559-6, Praziquantel (Biltricide), NPFAPI-02, BRN 0761557, SMR000037139, Bay-8440, Praziquantel (JAN/USP/INN), EMBAY-8440, FSVJFNAIGNNGKK-UHFFFAOYSA-N, 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one, 2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino[2,1-a]isoquinolin-4-one, 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, DSSTox_CID_1182, P 4668, 2-(cyclohexanecarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one, 2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a) isoquinolin-4-one, 4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, DSSTox_RID_75995, DSSTox_GSID_21182, 135526-78-2, Cisticid, (11bS)-2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazinoe(2,1a)isoquinolin-4-one, 2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one, SR-01000003100, Praziquantel, (R)-Isomer, Praziquantel, (S)-Isomer, saniquantrel, Praziquantel, (+-)-Isomer, Praziquantel,(S), NCGC00016877-01, Prestwick_402, CAS-55268-74-1, (+-)-Praziquantel, ACMC-20emeg, (+/-)-Praziquantel, Praziquantel [USAN:USP:INN:BAN:JAN], Spectrum_001119, Opera_ID_378, Prestwick0_000260, Prestwick1_000260, Prestwick2_000260, Prestwick3_000260, Spectrum2_001288, Spectrum3_000550, Spectrum4_000482, Spectrum5_001064, CHEMBL976, D0L9ZR, AC1L1J6N, Bayer Brand of Praziquantel, cid_4891, Merck Brand of Praziquantel, Lopac0_000909, Oprea1_163497, SCHEMBL44153, BSPBio_000080, BSPBio_002199, KBioGR_000963, KBioSS_001599, 5-24-03-00361 (Beilstein Handbook Reference), MLS000028528, MLS001201812, MLS001304085, MLS002548849, MLS006011880, DivK1c_000130, SPECTRUM1500494, SPBio_001295, SPBio_002299, BPBio1_000088, DTXSID9021182, SCHEMBL16019896, 8440, EMBAY, BDBM74574, CHEBI:91583, HMS500G12, KBio1_000130, KBio2_001599, KBio2_004167, KBio2_006735, KBio3_001699, Biltricide, Droncit, Praziquantel, MolPort-001-926-470, NINDS_000130, Praziquantel(Biltricide, Droncit), HMS1568D22, HMS1920J06, HMS2090J19, HMS2092A09, HMS2095D22, HMS3259K07, HMS3262F20, HMS3655O19, HMS3712D22, Pharmakon1600-01500494, BCP28525, HY-B0244, KS-000002NE, Tox21_110660, Tox21_201950, Tox21_302927, Tox21_500909, CCG-39773, CP0098, MFCD00058531, NSC757285, Praziquantel, anthelminic, neurogenic, s1691, STK030186, AKOS000541869, AKOS016398525, Tox21_110660_1, AC-8426, AN-8035, CS-2223, DB01058, LP00909, LS-7155, MCULE-1638759858, NC00468, NE56665, NSC-757285, RP17849, (+-)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1a)isoquinolin-4-one, IDI1_000130, NCGC00015818-04, NCGC00015818-05, NCGC00015818-06, NCGC00015818-07, NCGC00015818-08, NCGC00015818-11, NCGC00015818-12, NCGC00015818-14, NCGC00015818-15, NCGC00089733-02, NCGC00089733-03, NCGC00089733-04, NCGC00089733-05, NCGC00256422-01, NCGC00259499-01, NCGC00261594-01, AS-12459, BAS 00347357, CPD000037139, KB-59949, LS-23174, SAM002264632, SC-46696, TA-01001, SBI-0050884.P004, AB0011974, AB1009469, AB00052075, EU-0100909, FT-0630676, P2125, ST24049030, ST50904686, 1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one, 2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-, C07367, D00471, J10194, AB00052075-13, AB00052075-15, AB00052075_16, AB00052075_17, Praziquantel, VETRANAL(TM), analytical standard, 268P741, I06-0088, Praziquantel, Antibiotic for Culture Media Use Only, Q-201612, SR-01000003100-3, SR-01000003100-5, SR-01000003100-7, BRD-A21858158-001-05-2, BRD-A21858158-001-16-9, F0037-0136, Z1563145961, Praziquantel, European Pharmacopoeia (EP) Reference Standard, Praziquantel, United States Pharmacopeia (USP) Reference Standard, 10-(cyclohexylcarbonyl)-5,6,7,11a-tetrahydropiperazino[2,1-a]isoquinolin-8-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2,1- a]isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]-isoquinolin-4-one, 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-aisoquinolin-4-one, 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one, 2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one, Praziquantel for system suitability, European Pharmacopoeia (EP) Reference Standard, Praziquantel, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H

ID: 639

InChIKey: FSXRLASFHBWESK-HOTGVXAUSA-N
SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 515709
synonyms found at PubChem are:
phenylalanyltyrosine, 17355-18-9, H-Phe-Tyr-OH, CHEBI:73637, L-phenylalanyl-L-tyrosine, L-Tyrosine,L-phenylalanyl-, L-Tyrosine, L-phenylalanyl-, (S)-2-((S)-2-Amino-3-phenylpropanamido)-3-(4-hydroxyphenyl)propanoic acid, Phe-Tyr, L-Phe-L-Tyr, L-Phe-L-Tyr-OH, AC1LAL1E, L-Phenylalanin L-Tyrosin, Spectrum2_001496, Spectrum3_001813, BSPBio_003425, CHEMBL54572, SPBio_001511, SCHEMBL3037096, CTK4D4680, KBio3_002928, DTXSID30333656, FSXRLASFHBWESK-HOTGVXAUSA-N, FY, ZINC2384778, 7225AH, BDBM50049728, CCG-39203, L-Tyrosine, L-phenylalanyl-, monomer, AKOS022181529, NCGC00178074-01, AJ-35117, J-010920, BRD-K22337096-001-01-8, (2S)-2-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid, (2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid, Melanin synthesized from Phe-Tyr substrate catalyzed by tyrosinase for 40 hrs, F-Y

ID: 640

InChIKey: FTBGFGQPUMCUSC-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C=C2C(=C1O)C(=O)C(=CO2)C3=CC4=C(C=C3)OCO4)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5810067
synonyms found at PubChem are:
derrubone, 5,7-Dihydroxy-3',4'-methylenedioxy-6-prenylisoflavone, KBio2_007443, AC1NXMCX, Spectrum_001813, Spectrum2_000048, Spectrum3_000230, Spectrum4_000946, Spectrum5_001728, BSPBio_001879, KBioGR_001532, KBioSS_002309, SPECTRUM201650, SPBio_000175, CHEMBL412010, KBio2_002307, KBio2_004875, KBio3_001379, CHEBI:107656, CCG-40042, LMPK12050239, SDCCGMLS-0066443.P001, NCGC00095513-01, NCGC00095513-02, NCGC00178932-01, 22044-58-2, SR-05000002621, SR-05000002621-1, BRD-K59272984-001-02-6, 3-(1,3-benzodioxol-5-yl)-5,7-dihydroxy-6-(3-methylbut-2-enyl)chromen-4-one

ID: 641

InChIKey: FTLDJPRFCGDUFH-UHFFFAOYSA-N
SMILES: CC(C)(CC1=CC=CC=C1)N(C)C(=O)CN(CCO)CC(=O)N(C)C(C)(C)CC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4621
synonyms found at PubChem are:
Oxethazaine, Oxetacaine, 126-27-2, Mucaine, Oxaethacainum, Oxethacaine, Oxaine, Betalgil, Muthesa, Stomacain, Topicain, Oxethacaina [Italian], Tepilta, Oxetacainum [INN-Latin], Oxetacaina [INN-Spanish], UNII-IP8QT76V17, CCRIS 4692, EINECS 204-780-5, FH 099, WY 806, BRN 2404063, CHEMBL127592, IP8QT76V17, CHEBI:31947, Wy-806, Oxetacaine (INN), Oxetacaine [INN], 2,2'-((2-Hydroxyethyl)imino)bis(N-(1,1-dimethyl-2-phenylethyl)-N-methylacetamide), NCGC00016382-01, CAS-126-27-2, 2-Di(N-methyl-N-phenyl-tert-butyl-carbamoylmethyl)aminoethanol, DSSTox_CID_5818, N,N-Bis(N-methyl-N-phenyl-tert-butylacetamido)-beta-hydroxyethylamine, 2,2'-((2-Hydroxyethyl)imino)bis(N-(alpha,alpha-dimethylphenethyl)-N-methylacetamide), Acetamide, 2,2'-((2-hydroxyethyl)imino)bis(N-(1,1-dimethyl-2-phenylethyl)-N-methyl-, DSSTox_RID_77936, DSSTox_GSID_25818, Milzine, Acetamide, 2,2'-((2-hydroxyethyl)imino)bis(N-(alpha,alpha-dimethylphenethyl)-N-methyl-, Acetamide, 2,2'-[(2-hydroxyethyl)imino]bis[N-(1,1-dimethyl-2-phenylethyl)-N-methyl-, 2-[2-hydroxyethyl-[2-[methyl-(2-methyl-1-phenylpropan-2-yl)amino]-2-oxoethyl]amino]-N-methyl-N-(2-methyl-1-phenylpropan-2-yl)acetamide, N-(1,1-dimethyl-2-phenyl-ethyl)-2-[[2-[(1,1-dimethyl-2-phenyl-ethyl)-methyl-amino]-2-oxo-ethyl]-(2-hydroxyethyl)amino]-N-methyl-acetamide, SR-05000001851, Oxethazaine [USAN:JAN], storocaine, Storocain, Prestwick_767, degrees centEuEuOo, Spectrum_001657, AC1L1IKS, Prestwick0_000058, Prestwick1_000058, Prestwick2_000058, Prestwick3_000058, Spectrum2_001987, Spectrum3_001751, Spectrum4_000202, Spectrum5_001269, cid_4621, Oxethazaine (JP17/USAN), SCHEMBL24489, BSPBio_000215, BSPBio_003482, KBioGR_000803, KBioSS_002137, 4-12-00-02822 (Beilstein Handbook Reference), MLS002154188, DivK1c_000715, SPECTRUM1503279, SPBio_002136, SPBio_002173, BPBio1_000237, Oxethazaine, analytical standard, DTXSID0025818, HMS502D17, KBio1_000715, KBio2_002137, KBio2_004705, KBio2_007273, KBio3_002702, KS-00000GVG, FTLDJPRFCGDUFH-UHFFFAOYSA-N, MolPort-003-666-480, NINDS_000715, 13930-31-9 (hydrochloride), HMS1568K17, HMS1922A04, HMS2093C15, HMS2095K17, HMS2236A03, HMS3370M13, HMS3712K17, Pharmakon1600-01503279, BCP07626, HY-B0955, ZINC3874585, Tox21_110407, 2622AH, BDBM50017672, CCG-39525, LS-703, NSC758444, AKOS024284189, Tox21_110407_1, API0003711, CS-4432, DB12532, MCULE-5155939580, NSC-758444, IDI1_000715, NCGC00016382-02, NCGC00016382-03, NCGC00016382-04, NCGC00016382-07, NCGC00095039-01, NCGC00095039-02, NCGC00095039-03, AN-43561, CC-33412, SMR001233479, ST073363, SBI-0051816.P002, AB00052348, FT-0603332, C12552, D01152, AB00052348_08, AB00052348_09, 126O272, C-22674, J-005353, SR-05000001851-1, SR-05000001851-3, BRD-K56940463-001-05-4, BRD-K56940463-001-08-8, 2-Hydroxyethyliminobis[N-(alpha,alpha-dimethylphenethyl)-N-methyl-acetamide], 2,2'-((2-hydroxyethyl)imino)bis(N-alpha,alpha-dimethylphenethyl)-N-methylacetamide, 2,2'-(2-hydroxyethylazanediyl)bis(N-methyl-N-(2-methyl-1-phenylpropan-2-yl)acetamide), 2-Hydroxyethyliminobis[N-(alpha,alpha-dimethylphenethyl)-N-methyl- acetamide], 2-oCOO>>uNC degrees +/->>uE<<(N-[|A,|A- paragraph signthorn(1/4)x>>u+/-(1/2)OO>>u]-N-(1/4)x>>uOOo pound degrees .), N-(1,1-Dimethyl-2-phenyl-ethyl)-2-[{[(1,1-dimethyl-2-phenyl-ethyl)-methyl-carbamoyl]-methyl}-(2-hydroxy-ethyl)-amino]-N-methyl-acetamide, N-(1,1-dimethyl-2-phenylethyl)-2-({[N-(1,1-dimethyl-2-phenylethyl)-N-methylcar bamoyl]methyl}(2-hydroxyethyl)amino)-N-methylacetamide

ID: 642

InChIKey: FTNWXGFYRHWUKG-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 66069
synonyms found at PubChem are:
Triflupromazine hydrochloride, 1098-60-8, Flumazin, Fluorofen, Neoprin, Nivoman, Vesprin hydrochloride, Triflupromazine (hydrochloride), Triflupromazine monohydrochloride, Triflupromazine HCl, Trifluopromazine hydrochloride, Fluopromazine monohydrochloride, UNII-9E75N4A5HM, MC 4703, EINECS 214-149-6, Trifluopromazine hydrochloride (VAN), NSC 14959, NSC 17473, MLS000069672, 9E75N4A5HM, NCGC00094410-02, SMR000058517, 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine monohydrochloride, 10-(3-Dimethylaminopropyl)-2-(trifluoromethyl)phenothiazine hydrochloride, 10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-, monohydrochloride, DSSTox_CID_25804, DSSTox_RID_81142, DSSTox_GSID_45804, CHEBI:9712, Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(trifluoromethyl)-, monohydrochloride, C18H19F3N2S, NSC14959, NSC17473, WLN: T C666 BN ISJ B3N1&1 EXFFF, SR-01000000224, CAS-1098-60-8, C18H19F3N2S.ClH, SR-01000000224-4, 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine hydrochloride, dimethyl{3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl}amine, chloride, 10H-Phenothiazine-10-propanamine,N-dimethyl-2-(trifluoromethyl)-, monohydrochloride, Triflupromazine hydrochloride [JAN], Prestwick_893, Triflupromazine hydrochloride [USP:JAN], N,N-dimethyl-3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propan-1-amine hydrochloride, N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine;hydrochloride, Opera_ID_486, AC1L24JZ, Triflupromazine(hydrochloride), MLS001148408, MLS002222277, SCHEMBL317144, SPECTRUM1503118, REGID_for_CID_66069, CHEMBL1201102, DTXSID8045804, CTK8G3605, MolPort-003-666-452, HMS1568K07, HMS1922G15, Pharmakon1600-01503118, HY-B0909, Tox21_111276, Tox21_501146, 2767AH, NSC-14959, NSC-17473, NSC758387, SBB058191, AKOS024288004, Tox21_111276_1, API0004503, CCG-213116, LP01146, MCULE-4776607695, NSC-758387, KS-00001F94, NCGC00016012-12, NCGC00094410-01, NCGC00094410-03, NCGC00094410-04, NCGC00094410-05, NCGC00261831-01, Triflupromazine hydrochloride (JAN/USP), LS-105501, EU-0101146, FT-0736671, ST51015135, D00800, T 2896, J-002339, SR-01000000224-2, SR-01000000224-8, Z1642388275, Triflupromazine Hydrochloride 1.0 mg/ml in Methanol (as free base), Triflupromazine hydrochloride, VETRANAL(TM), analytical standard, 10-[3-(Dimethylamino)-1-propyl]-2-(trifluoromethyl)phenothiazine Hydrochloride, dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine hydrochloride, Phenothiazine, 10-(3-dimethylaminopropyl)-2-(trifluoromethyl)-, hydrochloride, Triflupromazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine hydrochloride, AC1LCW96, AKOS026749861, N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine; hydron; chloride

ID: 643

InChIKey: FTSCEGKYKXESFF-LXTVHRRPSA-N
SMILES: CCCCCCCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Parenti" "M Forcella" "J Désiré" "C Norez" "J Bertrand" "V Cendret" "T Legigan" "I Adachi" "Y Blériot" "A Mingot" "F Becq" "A Kato" "S Thibaudeau"

CID is 501640
synonyms found at PubChem are:
N-Nonyldeoxynojirimycin, N-(N-NONYL)DEOXYNOJIRIMYCIN, NN-DNJ, 81117-35-3, N-Nonyl-deoxynojirimycin, (2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol, CHEBI:76399, N-nonyl-1-deoxynojirimycin, N-Nonyl-DNJ, AC1L9V9L, N-Nonyl 1-Deoxynojirimycin, N-(n-Nonyl)-deoxynojirimycin, (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol, BICL4182, CHEMBL408500, SCHEMBL2268575, BDBM18358, CTK8G1326, DTXSID60333407, MolPort-023-276-901, ZINC14253608, NN-DNJ, >=98% (HPLC), AKOS024457751, DB08283, NCGC00182087-01, N-(n-Nonyl)-1-deoxynojirimycin min. 99%, B7472, W-203849, (2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonyl-piperidine-3,4,5-triol, (5S,2R,3R,4R)-2-(Hydroxymethyl)-1-nonylpiperidine-3,4,5-triol, 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-nonyl-, (2R,3R,4R,5S)-

ID: 644

InChIKey: FTVWIRXFELQLPI-CYBMUJFWSA-N
SMILES: C1[C@@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazur" "S Barnes" "J Prasain" "SM Rowe" "JP Clancy" "LC Pyle" "JC Fulton" "PA Sloane" "K Backer"

CID is 667495
synonyms found at PubChem are:
(2R)-naringenin, (R)-naringenin, (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, naringenin, (S)-Naringenin, 480-41-1, (+)-(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, (-)-Naringenin, 17654-19-2, R-naringenin, (+)-naringenin, AC1LDI7C, ZINC1785, SCHEMBL17166263, CHEBI:50201, MolPort-002-507-277, (2R)-5,7,4'-trihydroxyflavone, HMS3468H18, (2R)-4',5,7-trihydroxyflavanone, ALBB-015405, BBL010488, MFCD03265520, STK801623, AKOS004119880, MCULE-5852778653, (2R)-4',5,7-trihydroxyflavan-4-one, AJ-08090, SC-85987, ZB000410, BB 0261506, N1370, R6691, ST24036200, (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one, 4H-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2R)-

ID: 645

InChIKey: FTVWIRXFELQLPI-ZDUSSCGKSA-N
SMILES: C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazur" "S Barnes" "J Prasain" "SM Rowe" "JP Clancy" "LC Pyle" "JC Fulton" "PA Sloane" "K Backer"

CID is 439246
synonyms found at PubChem are:
naringenin, 480-41-1, (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, (2S)-Naringenin, naringetol, pelargidanon, salipurpol, Asahina, (S)-Naringenin, Salipurol, UNII-HN5425SBF2, CCRIS 5839, C15H12O5, YSO1, (-)-(2S)-Naringenin, CHEMBL9352, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, AI3-23355, HN5425SBF2, CHEBI:17846, (-)-Naringenin, Flavanone, 4',5,7-trihydroxy- (8CI), NSC 11855, (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-, NAR, EINECS 207-550-2, pelargidanon 1602, (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, SR-01000721771, (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, NSC-11855, 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 2uxu, 4deu, Spectrum_000247, 4eh3, Spectrum2_000325, Spectrum3_000567, Spectrum4_000124, Spectrum5_001423, D02ABO, 4',5,7-triOH-Flavone, AC1L96YW, SCHEMBL20570, BSPBio_001954, KBioGR_000508, KBioSS_000727, MLS000574861, BIDD:ER0116, DivK1c_000118, SPECTRUM1500746, SPBio_000329, 4',5, 7-Trihydroxyflavanone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, AC1Q78P1, DTXSID1022392, BDBM23419, CTK8C4789, HMS500F20, KBio1_000118, KBio2_000727, KBio2_003295, KBio2_005863, KBio3_001454, FTVWIRXFELQLPI-ZDUSSCGKSA-N, MolPort-001-796-145, NINDS_000118, (2S)-5,7,4'-trihydroxyflavone, AIDS001417, HMS2202M06, ZINC156701, (2S)-4',5,7-trihydroxyflavanone, HY-N0100, KS-000010IV, TNP00287, 2580AH, ANW-73132, CCG-38601, LMPK12140001, Phytochemistry 8: 127 (1969), s2394, AKOS016843490, CS-6421, DB03467, RTR-017609, SDCCGMLS-0066570.P001, (2S)-4',5,7-trihydroxyflavan-4-one, IDI1_000118, NCGC00016457-01, NCGC00016457-02, NCGC00016457-03, NCGC00017346-01, NCGC00163598-01, AJ-13871, CAS-480-41-1, SMR000156272, ZB006427, FT-0617134, FT-0617135, C00509, Q-100666, SR-01000721771-3, SR-01000721771-4, BRD-K08832567-001-02-4, BRD-K08832567-001-06-5, (-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one, (S)-2,3-dihydo-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 13308-00-4, 15912-71-7

ID: 646

InChIKey: FUMINTAAUJUVMP-UHFFFAOYSA-N
SMILES: C1CN(CCC1N)C2=NC(=CC=C2)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 131746
synonyms found at PubChem are:
SR 57227A, 77145-61-0, SR 57227 HYDROCHLORIDE, SR 57227A hydrochloride, UNII-OW45B79UZD, 4-amino-1-(6-chloro-2-pyridyl)-piperidine hydrochloride, SR-57227A, CM57227, OW45B79UZD, SR 57,227A, 1-(6-chloro-2-pyridinyl)-4-piperidinamine hydrochloride, 4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride, 1-(6-Chloro-2-pyridinyl)-4-piperidinamine monohydrochloride, 4-Amino-1-(6-chloro-2-pyridyl)piperidine monohydrochloride, 4-Piperidinamine, 1-(6-chloro-2-pyridinyl)-, monohydrochloride, DSSTox_CID_25201, DSSTox_RID_80745, DSSTox_GSID_45201, 1-(6-chloropyridin-2-yl)piperidin-4-amine hydrochloride, SMR000449299, CAS-77145-61-0, SR-01000075564, NCGC00015931-04, 1-(6-chloropyridin-2-yl)piperidin-4-amine hydrochloride(1:1), AC1Q3BCO, C10H14ClN3.HCl, SR 57227A, solid, AC1L2ZQ2, MLS000758285, MLS001424006, SCHEMBL3282207, sr57227, CHEMBL1256322, DTXSID5045201, MolPort-003-959-507, Tox21_110263, BN0505, MFCD01756430, AKOS024456463, Tox21_110263_1, API0008440, CCG-100768, LP01066, NC00018, NCGC00015931-07, NCGC00094345-01, CPD000449299, SAM001246999, KB-147557, LS-113853, B6632, EU-0101066, X6887, SR-01000075564-2, SR-01000075564-3, [1-(6-chloropyridin-2-yl)piperidin-4-yl]amine hydrochloride, AC1Q1T0S

ID: 647

InChIKey: FUQAYSQLAOJBBC-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC3(CCCC2(C3)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 61125
synonyms found at PubChem are:
beta-Caryophyllene alcohol, Caryophyllenol, Caryolan-1-ol, 472-97-9, Tricyclo[6.3.1.02,5]dodecan-1-ol, 4,4,8-trimethyl-, (1R,2S,5R,8S)-, beta-caryolan-1-ol, Spectrum_000678, SpecPlus_000224, AC1L1UKR, Spectrum2_001727, Spectrum3_001279, Spectrum4_001455, Spectrum5_000069, 4,4,8-Trimethyltricyclo(6.3.1.02,5)dodecan-1-ol, BSPBio_002878, KBioGR_001969, KBioSS_001158, SPECTRUM300105, DivK1c_006320, SPBio_001774, SCHEMBL3508459, CHEMBL1374805, KBio1_001264, KBio2_001158, KBio2_003726, KBio2_006294, KBio3_002378, FUQAYSQLAOJBBC-UHFFFAOYSA-N, CCG-38795, SDCCGMLS-0066495.P001, NCGC00095583-01, NCGC00095583-02, AN-23476, SR-05000002464, SR-05000002464-1, 4,4,8-Trimethyl-Tricyclo(6.3.1.02,5)dodecan-1-ol, 4,4,8-trimethyltricyclo[6.3.1.0;{2,5}]dodecan-1-ol, 4,4,8-Trimethyltricyclo[6.3.1.02,5]dodecan-1-ol, 9CI

ID: 648

InChIKey: FUQOTYRCMBZFOL-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1Cl)C=C(N2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 82693
synonyms found at PubChem are:
5-Chloroindole-2-carboxylic acid, 10517-21-2, 5-Chloro-1H-indole-2-carboxylic acid, 5-Chloroindole-2-carboxylate, 1H-Indole-2-carboxylic acid, 5-chloro-, EINECS 234-050-1, BRN 0153229, FUQOTYRCMBZFOL-UHFFFAOYSA-N, Spectrum_000183, 5-Chloroindoline-2-carboxylicacid, PubChem1670, ACMC-1BZTJ, SpecPlus_000670, Spectrum2_000513, Spectrum3_000783, Spectrum4_001044, Spectrum5_001833, Biomol-NT_000198, 2-Carboxy-5-chloro-indole, AC1Q73TG, NCIOpen2_000893, 5-chloroindolecarboxylic acid, Oprea1_643267, BSPBio_002486, KBioGR_001308, KBioSS_000663, KSC181I8F, MLS002207052, CHEMBL23906, DivK1c_006766, SCHEMBL720582, SPECTRUM1502057, SPBio_000465, AC1L33X8, BPBio1_001228, 5-Chloroindole-2-carboxylicacid, Jsp000495, CTK0I1482, KBio1_001710, KBio2_000663, KBio2_003231, KBio2_005799, KBio3_001706, KS-00000NGC, 5-chloro-2-indolecarboxylic acid, 5-chloroindole-2-carboxylic-acid, DTXSID60146993, CHEBI:107646, MolPort-000-148-158, 5-chloro indole-2-carboxylic acid, 5-chloro-indole-2-carboxylic acid, ZINC164954, ACT03581, ALBB-006019, BCP15099, NSC75651, 5chloro-1H-indole-2-carboxylic acid, ANW-15178, BBL001474, CCG-39574, CL3504, HTS000962, MFCD00005613, NSC-75651, SBB003591, STK287956, 5-chloro-indole-2-carbo--xylic acid, 5-Chloro-1H-indol-2-carboxylic acid, AKOS000137114, AC-8793, AN-7657, CG-0517, CS-W007385, MCULE-5711501424, RL00239, RP04019, RTC-060641, TRA0013214, VI30019, 5-chloro-1 H-indole-2-carboxylic acid, 5-Chloroindole-2-carboxylic acid, 98%, NCGC00095877-01, NCGC00095877-02, NCGC00095877-03, AJ-16329, BP-11766, BR-28711, I798, KB-73467, LS-82555, SC-00214, SMR001306706, AB0013897, AB1005637, DB-012761, KB-245386, ST2418704, TC-060641, TL8000199, 4CH-015451, A1974, AM20061127, BB 0248943, C1868, FT-0620319, ST50406277, EN300-28911, M-2316, 517C212, BRD-K57244822-001-03-1, 3ZB

ID: 649

InChIKey: FUSNMLFNXJSCDI-UHFFFAOYSA-N
SMILES: CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5510
synonyms found at PubChem are:
tolnaftate, 2398-96-1, Tolnaphthate, Tinactin, Tonoftal, Sporiline, Tinaderm, Tolsanil, Aftate, Chinofungin, Dermoxin, Focusan, Tinavet, Pitrex, Naphthiomate T, Phytoderm, Tolnaftato, Tolnaftatum, Timoped, Tritin, HI-Alazin, Fungistop, Sorgoa, Dungistop, Tniaderm, Separin, Tolnaftato [DCIT], Naphthiomate-T, Hi-alarzin, O-2-Naphthyl m,N-dimethylthiocarbanilate, Tolnaftatum [INN-Latin], Sch 10144, 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, Tolnaftato [INN-Spanish], Genaspore cream, Tinactin powder, Tinavet (Veterinary), Tinactin cream, Pitrex cream, Ting Products, Tinactin solution, Zeasorb-AF powder, Tinactin (TN), Prestwick_472, Separin (TN), NP-27 Solution, Tinactin plus powder, Dr. Scholl's athlete's foot spray, Ting antifungal cream, NP-27 Powder, m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester, Ting antifungal powder, NP-27 Cream, Tinactin aerosol liquid, Tinactin aerosol powder, NP-27 Spray Powder, Tinactin jock itch cream, Aftate for jock itch gel, Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester, Tinactin plus aerosol powder, Ting antifungal spray liquid, Ting antifungal spray powder, Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester, Tolnaftate(USAN), UNII-06KB629TKV, Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester, Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester, Aftate for athlete's foot gel, NSC 233648, TOLNAFRATE, Tinactin jock itch spray powder, MLS000028526, Tinactin jock itch aerosol powder, Tolnaftate [USAN:BAN:INN:JAN], Tolnaftate [USAN:INN:BAN:JAN], Aftate for jock itch sprinkle powder, EINECS 219-266-6, Tolnaftate (JP14/USP), Tolnaftate (JP15/USP), BRN 2752620, O-2-Naphthyl N,N-dimethylthiocarbanilate, SMR000058288, C19H17NOS, Aftate for jock itch aerosol spray powder, Tinactin antifungal deodorant powder aerosol, 06KB629TKV, CHEBI:9620, O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate, FUSNMLFNXJSCDI-UHFFFAOYSA-N, N-methyl-N-(3-methylphenyl)-1-naphthalen-2-yloxy-methanethioamide, Carbamothioic acid, N-methyl-N-(3-methylphenyl)-, O-2-naphthalenyl ester, O-2-naphthyl methyl(3-methylphenyl)carbamothioate, NCGC00016610-01, Aftate for athlete's foot sprinkle powder, Methyl-[3-methylphenyl]-carbamothioic acid O-2-naphthyl ester, CAS-2398-96-1, Aftate for athlete's foot aerosol spray liquid, Aftate for athlete's foot aerosol spray powder, DSSTox_CID_22477, DSSTox_RID_80034, DSSTox_GSID_42477, O-2-Naphthyl methyl(3-methylphenyl)thiocarbamate, 94256-64-1, o-(2-Naphthyl) methyl(3-methylphenyl)thiocarbamate, O-(2-naphthyl) N-methyl-N-(m-tolyl)carbamothioate, W-107363, O-naphthalen-2-yl methyl(3-methylphenyl)carbamothioate, Breezee, Genaspor, Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester, Micoisdin, O-Naphthalen-2-yl N-Methyl-N-(3-Methylphenyl)Thiocarbamate, Tinatox, Ting, ZeaSorb, N-Methyl-(3-methylphenyl)-carbamothioic acid, O-2-naphthalenyl ester, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide, Ony Clear, Ony-Clear, Tolnaftat Purder N, Purder N, Tolnaftat, SR-01000003084, Tolnaflate, NP27, Tolnaftate-10KG, Absorbine (TN), NP 27, Carbamothiolic Acid, Genaspor (TN), Aftate (TN), Odor Eaters (TN), Scholl (TN), Lamasil AF (TN), Tolnaftate [USAN:USP:INN:BAN:JAN], Ting (TN), Spectrum_000963, N-dimethylthiocarbanilate, Tolnaftate Douglas Brand, Opera_ID_1698, Prestwick0_000070, Prestwick1_000070, Prestwick2_000070, Prestwick3_000070, Spectrum2_000950, Spectrum4_000360, Spectrum5_001000, Tolnaftate Schering Brand, Essex Brand of Tolnaftate, Isdin Brand of Tolnaftate, D02NTO, Zenith Brand of Tolnaftate, AC1L1KI4, Bioglan Brand of Tolnaftate, cid_5510, Douglas Brand of Tolnaftate, Insight Brand of Tolnaftate, SCHEMBL3520, Stiefel Brand of Tolnaftate, Chinosol Brand of Tolnaftate, Schering Brand of Tolnaftate, Thompson Brand of Tolnaftate, BSPBio_000259, KBioGR_000799, KBioSS_001443, MLS001146910, ARONIS24597, CHEMBL83668, DivK1c_000334, SPECTRUM1500583, SPBio_000920, SPBio_002180, Pedinol Brand 1 of Tolnaftate, Pedinol Brand 2 of Tolnaftate, BPBio1_000285, Tolnaftate (JP15/USP/INN), Tolnaftate (JP17/USP/INN), Wernigerode Brand of Tolnaftate, DTXSID3042477, BDBM39349, CTK5H6131, HMS501A16, KBio1_000334, KBio2_001443, KBio2_004011, KBio2_006579, KS-00000ZUQ, ZINC57522, MolPort-002-893-958, NINDS_000334, HMS1568M21, HMS1921E21, HMS2092O05, HMS2095M21, HMS2231O21, HMS3373P10, HMS3655D15, HMS3712M21, NP 27 (TN), Pharmakon1600-01500583, Carter Wallace Brand of Tolnaftate, BCP12071, HY-B0370, KS-000046KG, Tox21_110521, Tox21_301363, MFCD00056611, NSC233648, NSC757355, s2058, SCH-10144, STL069548, AKOS005111014, Schering-Plough Brand 1 of Tolnaftate, Schering-Plough Brand 2 of Tolnaftate, Tox21_110521_1, AC-5548, API0004445, CCG-212827, CS-2427, DB00525, KS-5115, MCULE-6942707513, NSC-233648, NSC-757355, IDI1_000334, NCGC00016610-02, NCGC00016610-03, NCGC00016610-04, NCGC00016610-05, NCGC00016610-07, NCGC00016610-08, NCGC00023506-03, NCGC00255761-01, AN-10909, CC-35091, LS-51199, Q770, SC-16758, ZB002142, Carbamothioic acid, O-2-naphthalenyl ester, SBI-0051538.P002, AB2000462, TR-011103, AB00052111, FT-0603605, D00381, K-6488, O-naphthalen-2-yl methyl(m-tolyl)carbamothioate, AB00052111_17, AB00052111_18, N-Dimethylthiocarbanilic acid O-2-naphthyl ester, 398T961, C-19112, O-(naphthalen-2-yl) methyl(m-tolyl)carbamothioate, Carbanilic acid,m-dimethylthio-, O-2-naphthyl ester, Carbanilic acid,N-dimethylthio-, O-2-naphthyl ester, SR-01000003084-2, SR-01000003084-4, BRD-K44273375-001-04-5, BRD-K44273375-001-14-4, BRD-K44273375-001-23-5, O-(2-Naphthyl) methyl(3-methylphenyl)thiocarbamate #, Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester, N-methyl-N-(m-tolyl)thiocarbamic acid O-(2-naphthyl) ester, Tolnaftate, European Pharmacopoeia (EP) Reference Standard, Tolnaftate, United States Pharmacopeia (USP) Reference Standard, N-methyl-N-(3-methylphenyl)carbamothioic acid O-(2-naphthalenyl) ester, Tolnaftate, Pharmaceutical Secondary Standard; Certified Reference Material, Tolnaftate for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 650

InChIKey: FUZBPOHHSBDTJQ-CFOQQKEYSA-L
SMILES: C[C@H](CC1=CC2=C(C=C1)OC(O2)(C(=O)[O-])C(=O)[O-])NC[C@@H](C3=CC(=CC=C3)Cl)O.[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5312115
synonyms found at PubChem are:
CL 316,243, UNII-CF9MRO9QWW, CL-316243, 138908-40-4, CF9MRO9QWW, CL-316,243, CL316243, BTA-243, CL 316243, CL316,243, FUZBPOHHSBDTJQ-CFOQQKEYSA-L, Disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate, CHEMBL32590, Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate, 151126-84-0, disodium 5-[(2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}propyl]-1,3-benzodioxole-2,2-dicarboxylate, 1,3-Benzodioxole-2,2-dicanboxylic acid, 5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)propyl)-, disodium salt, (R-(R*,R*))-, CL-316243 sodium, AC1NSM16, SCHEMBL2016430, DTXSID6041004, MolPort-003-940-777, HMS3260L12, Tox21_500295, 138908-40-4 (sodium salt), AKOS024456637, API0008511, LP00295, NCGC00093745-01, NCGC00260980-01, AS-16747, CC-20995, EU-0100295, FT-0697629, C 5976, 102718-EP2272841A1, 102718-EP2301936A1, 5-[(2R)-2-([(2R)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYL]AMINO)PROPYL]-1,3-BENZODIOXOLE-2,2-DICARBOXYLATE DISODIUM, 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt, sodium 5-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)benzo[d][1,3]dioxole-2,2-dicarboxylate, AOB33751, NCGC00092282-01

ID: 651

InChIKey: FUZMQNZACIFDBL-KYJUHHDHSA-N
SMILES: CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(CCN6C)C(=C(C(=C7O3)OC)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 72343
synonyms found at PubChem are:
Hernandezine, (+)-Hernandezine, 6681-13-6, CHEBI:5677, (1|A)-5,6,6',7,12-pentamethoxy-2,2'-dimethylberbaman, AC1L2HVY, pentamethoxy(dimethyl)[?], NSC626650, AC1Q58FE, CHEMBL504936, SCHEMBL16254179, DTXSID40216926, BDBM50201796, ZINC19685806, AKOS015969728, CCG-208358, C09461, SR-05000002295, SR-05000002295-2, Berbaman, 5,6,6',7,12-pentamethoxy-2,2'-dimethyl-, (1beta)-, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-, (4aS,16aS)-

ID: 652

InChIKey: FVLVBPDQNARYJU-UHFFFAOYSA-N
SMILES: CC1CCC(CC1)NC(=O)N(CCCl)N=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5198
synonyms found at PubChem are:
semustine, Methyl-CCNU, 13909-09-6, MeCCNU, METHYL CCNU, trans-Methyl-CCNU, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, Lomustine, methyl-, Semustina, Semustinum, NSC 95441, ICIG 1110, Semustine [USAN:INN], Semustinum [INN-Latin], UNII-EGU4CMI14D, Semustina [INN-Spanish], NCI-C04955, Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, Lomustine, methyl, UNII-2281H4FBL9, CCRIS 6336, N-(2-Chloroethyl)-N'-(4-methylcyclohexyl)-N-nitrosourea, NSC95441, EGU4CMI14D, NSC 135091, CHEBI:6863, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, 1-(2-Chloroethyl)-3-(trans-4-methylcyclohexane)-1-nitrosourea, 2281H4FBL9, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, trans-, UNII-6YY7T1T567, 33185-87-4, Methyl-CCNU [Chloroethyl nitrosoureas], NCGC00095051-01, cis-1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, N-(2-Chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea, Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, cis-, Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, trans-, 33073-59-5, 1-(2-Choroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-urea, Urea,N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, trans-Semustine, cis-Semustine, Urea, 3-(beta-chloroethyl)-1-(4-methylcyclohexyl)-3-nitroso-, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, (Z)-, 1-(2-Chloroethyl)-1-([(4-methylcyclohexyl)amino]carbonyl)-2-oxohydrazine, cis-Methyl CCNU, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea [Chloroethyl nitrosoureas], SMR000058889, trans-Methyl CCNU, 6YY7T1T567, MeCCNU (trans), Me-CCNU, 1-[2-Chloroethyl]-3-[4-methylcyclohexyl]-1-nitrosourea, methyl lomustine, 1-(2-Chloroethyl)-1-(((4-methylcyclohexyl)amino)carbonyl)-2-oxohydrazine, HSDB 7760, NSC-95441, Prestwick_1013, Spectrum_001335, AI3-52897, Semustine (USAN/INN), AC1L1JTC, AC1Q5MLQ, Spectrum2_000911, Spectrum3_000966, Spectrum4_001084, Spectrum5_001087, SCHEMBL4500, DSSTox_CID_11603, DSSTox_RID_78887, DSSTox_GSID_31603, BSPBio_002571, KBioGR_001468, KBioSS_001815, MLS000069831, MLS001074931, CHEMBL12948, DivK1c_000020, SPECTRUM1503422, SPBio_000782, SCHEMBL4959160, CHEMBL1967746, CHEMBL2051944, DTXSID8031603, CTK4C1614, HMS500A22, KBio1_000020, KBio2_001815, KBio2_004383, KBio2_006951, KBio3_001791, FVLVBPDQNARYJU-UHFFFAOYSA-N, NINDS_000020, HMS1922C16, HMS2093E21, Pharmakon1600-01503422, 1-trans-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, KS-000018RB, ZINC3874951, Tox21_111404, CCG-39897, LS-814, NSC135091, NSC758471, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, cis-, Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, cis- (9CI), API0004155, NSC-135091, NSC-758471, IDI1_000020, QTL1_000073, NCGC00095051-02, NCGC00095051-03, NCGC00095051-04, NCI60_042122, SBI-0051825.P002, CAS-13909-09-6, LS-159442, C07640, D05822, AB01563283_01, 909S096, SR-01000763446, J-007221, SR-01000763446-2, 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosoure, 1-(2-Chloroethyl)-3-(4-methyl-cyclohexyl)-1-nitrosourea, UNII-6YY7T1T567 component FVLVBPDQNARYJU-DTORHVGOSA-N, UNII-6YY7T1T567 component FVLVBPDQNARYJU-KYZUINATSA-N, 1-(2-Chloroethyl)-3-(4alpha-methylcyclohexan-1alpha-yl)-1-nitrosourea, 1-(2-Chloroethyl)-3-(4beta-methylcyclohexan-1alpha-yl)-1-nitrosourea, Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, cis- (8CI), Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, trans- (8CI), 56748-54-0

ID: 653

InChIKey: FVWJYYTZTCVBKE-ROUWMTJPSA-N
SMILES: CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 72326
synonyms found at PubChem are:
Betulin, 473-98-3, Betulinol, Betuline, Trochol, Betulol, Lup-20(29)-ene-3b,28-diol, Lup-20(29)-ene-3beta,28-diol, UNII-6W70HN7X7O, C30H50O2, NSC 4644, EINECS 207-475-5, Lup-20(30)-ene-3beta,28-diol, AI3-62999, 6W70HN7X7O, CHEBI:3086, Lup-20(29)-ene-3,28-diol, (3beta)-, (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(Hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol, Betulinic alcohol, lup-20(29)-ene-3 beta,28-diol, (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymethyl)-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosan-17-ol, (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol, SR-05000002167, NSC4644, NSC-4644, NSC692218, (3beta)-lup-20(29)-ene-3,28-diol, Betulin, 23, Betulin, >=98%, Prestwick3_000990, D05KJY, AC1L2HV4, Betulin, analytical standard, BSPBio_001059, ARONIS24303, CHEMBL23236, SCHEMBL131739, BPBio1_001165, MEGxp0_001726, ACon1_000091, BDBM23207, FVWJYYTZTCVBKE-ROUWMTJPSA-N, MolPort-001-742-486, HMS2098E21, HY-N0083, ZINC3978650, MFCD00016802, SBB080743, Lup-20(29)-ene-3 ,28-diol, AKOS005267212, Lup-20(29)-ene-3beta, 28-diol, ACN-035289, AN-8466, API0001703, CCG-208619, CS-6156, GS-3254, LMPR0106140005, NSC-692218, RL03767, NCGC00168803-01, NCGC00168803-02, NCGC00168803-04, AJ-47572, AK-72923, BR-72923, CC-24647, LS-88195, SC-47257, AX8001985, ST2413202, AB00513988, B0803, N1290, V0184, (3.beta.)-Lup-20(29)-ene-3,28-diol, C08618, S-1793, 473B983, C-22391, Q-100501, SR-05000002167-2, SR-05000002167-3, BRD-K64874225-001-01-3, NCGC00168803-04_C30H50O2_Lup-20(29)-ene-3,28-diol, (3beta)-, (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymethyl)-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0(2),(1)?.0?,?.0(1)?,(1)?]henicosan-17-ol, (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3 a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol, (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(Hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-e, (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol, (5S,17S,1R,2R,8R,9R,10R,13R,14R,19R)-5-(hydroxymethyl)-1,2,14,18,18-pentamethy l-8-(1-methylvinyl)pentacyclo[11.8.0.0<2,10>.0<5,9>.0<14,19>]henicosan-17-ol

ID: 654

InChIKey: FVXYCYOANPHZHB-ZSWFMMJVSA-N
SMILES: C[C@@]12CCC3[C@@]4([C@H](C(C5(C(C4=O)C[C@]3(C1=CC(=O)O[C@H]2C6=COC=C6)O5)Cl)(C)C)CC(=O)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708564
synonyms found at PubChem are:
SPBio_000072, Spectrum_000642, SpecPlus_000131, Spectrum2_000256, Spectrum3_000039, Spectrum4_001321, Spectrum5_000161, BSPBio_001737, KBioGR_001781, KBioSS_001122, DivK1c_006227, KBio1_001171, KBio2_001122, KBio2_003690, KBio2_006258, KBio3_000877, CCG-39940, NCGC00179045-01, 3-CHLORO-8beta-HYDROXYCARAPIN, 3,8-HEMIACETAL, BRD-A66979321-001-02-1

ID: 655

InChIKey: FVYXIJYOAGAUQK-UHFFFAOYSA-N
SMILES: C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 72303
synonyms found at PubChem are:
Honokiol, 35354-74-6, 5,3'-Diallyl-2,4'-dihydroxybiphenyl, NSC 293100, Honokiol,(S), 3,5'-Diallyl-4,2'-dihydroxybiphenyl, UNII-11513CCO0N, 3',5-Diallylbiphenyl-2,4'-diol, CPD000387107, CHEMBL16901, CHEBI:5759, 3',5-diallyl-[1,1'-biphenyl]-2,4'-diol, 4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol, 11513CCO0N, 3',5-diallyl-2,4'-biphenyldiol, 5,3′-Diallyl-2,4′-dihydroxydiphenyl, Q-100425, [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl-, SMR000387107, 3',5-di(prop-2-en-1-yl)biphenyl-2,4'-diol, houpa, Honokiol, HO, 5,3&prime, AC1L2HTG, D04DQJ, AC1Q7A9U, Honokiol, analytical standard, cid_72303, MLS000759481, MLS001048916, MLS001423980, MLS006011755, SCHEMBL133034, REGID_for_CID_72303, ZINC1536, CTK5J3931, KS-00000NQF, DTXSID30188845, 3',1'-biphenyl)-2,4'-diol, FVYXIJYOAGAUQK-UHFFFAOYSA-N, MolPort-002-507-432, HMS2051C12, HMS2271J07, HMS3393C12, HMS3656G03, BCP28282, HY-N0003, 3',5'-Diallyl-2,4'-biphenyldiol, 5,3'-Diallyl-biphenyl-2,4'-diol, AC-486, ANW-56605, BBL027819, BDBM50157304, BN0719, MFCD00016674, NSC293100, s2310, STK801954, 3'',5-diallylbiphenyl-2,4''-diol, Honokiol, >=98% (HPLC), powder, AKOS005622639, 3',5-Diallyl-2,4'-dihydroxybiphenyl, ACN-035410, API0002927, AT-5464, CCG-100864, CS-1696, MCULE-5001549020, NC00114, NSC-293100, RTR-014635, VZ32385, 5,3''-Diallyl-biphenyl-2,4''-diol, SMP2_000040, NCGC00163567-01, NCGC00163567-02, NCGC00163567-03, 4CN-0876, AJ-08043, AK-25837, AN-15767, AS-15333, BC205226, O900, SAM001246690, SC-17371, AB0016711, AX8008971, LS-174528, TR-014635, 5,3''''-Diallyl-biphenyl-2,4''''-diol, FT-0601638, N1672, ST24044036, C10630, J10347, W-2613, 354H746, SR-01000758208, I06-0428, SR-01000758208-5, {1,1'-Biphenyl]-2,4'-diol, 3,5-di-2-propenyl-, 3'',5-di-2-propenyl-1,1''-biphenyl-2,4''-diol, BRD-K98493452-001-01-6, 2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol, 3',5-Di-2-propen-1-yl[1,1'-biphenyl]-2,4'-diol, Honokiol, European Pharmacopoeia (EP) Reference Standard, [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propen-1-yl-, InChI=1/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H

ID: 656

InChIKey: FWKQNCXZGNBPFD-UHFFFAOYSA-N
SMILES: CC1=C2C=CC(=C2C=C(C=C1)C(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3515
synonyms found at PubChem are:
guaiazulene, 489-84-9, 1,4-Dimethyl-7-isopropylazulene, 7-Isopropyl-1,4-dimethylazulene, Vetivazulen, Azulon, Azunol, Eucazulen, Guajazulene, Kessazulen, Purazulen, Silazulon, Uroazulen, S-Guaiazulene, Cuteazul, Guiazulene, Gurjunazulen, Azulen-beris, 3,8-Dimethyl-5-(2-propyl)azulene, Azulene, 1,4-dimethyl-7-(1-methylethyl)-, 1,4-Dimethyl-7-(1-methylethyl)azulene, Azulol, 1,4-dimethyl-7-(propan-2-yl)azulene, guaiazulen, Vaumigan, hepatoprotectant, UNII-2OZ1K9JKQC, NSC 4714, AZ-8 beris, Azunol (TN), 7-isopropyl- 1,4-dimethylazulene, 7-isopropyl-1,4-dimethyl-azulene, AZULENE, 1,4-DIMETHYL-7-ISOPROPYL-, EINECS 207-701-2, 2OZ1K9JKQC, Azulene, 7-isopropyl-1,4-dimethyl-, BRN 1365001, CHEBI:5550, 1,4-dimethyl-7-propan-2-ylazulene, C15H18, 1,4-Dimethyl-7-isopropylazulene (JAN), NCGC00095836-02, Azulene, 7-isopropyl-1,4-dimethyl- (8CI), DSSTox_CID_25996, DSSTox_RID_81279, DSSTox_GSID_45996, CAS-489-84-9, Eucazulene, Guajazulen, Kessazulene, Guaiazulene 98%, Guaiazulene, 99%, Azulene,4-dimethyl-, PubChem15731, Spectrum_001198, Spectrum2_001089, Spectrum3_001537, Spectrum4_000762, Spectrum5_001090, AC1L1G3Z, BSPBio_002954, KBioGR_001144, KBioSS_001678, 4-05-00-01751 (Beilstein Handbook Reference), KSC492A3L, MLS002207286, 1,3,5,7,9-Guaiapentaene, DivK1c_001006, SPECTRUM1502249, SPBio_001138, AZ-8, CHEMBL1408759, DTXSID7045996, CTK3J2035, HMS503I13, KBio1_001006, KBio2_001678, KBio2_004246, KBio2_006814, KBio3_002454, Azulene,4-dimethyl-7-isopropyl-, NSC4714, FWKQNCXZGNBPFD-UHFFFAOYSA-N, MolPort-001-766-757, NINDS_001006, 1, 4-Dimethyl-7-isopropylazulene, ZINC968478, 1,4-Dimethyl-7-isopropyl-Azulene, BB_NC-01536, KS-000001GN, NSC-4714, ZX-AT020641, Tox21_111526, ANW-41603, BBL027440, CCG-40099, MFCD00003811, STK801958, 1,4-dimethyl-7-(methylethyl)azulene, 1,4-dimethyl-7-propan-2-yl-azulene, 1,4-Dimethyl-7-(prop-2-yl)azulene, AKOS001082716, Tox21_111526_1, LMPR0103410006, MCULE-9349286347, OR28914, RTR-017759, SDCCGMLS-0066686.P001, WLN: L57J B1 F1 IY1&1, IDI1_001006, Azulene,4-dimethyl-7-(1-methylethyl)-, NCGC00095836-01, NCGC00095836-03, NCGC00095836-05, NCGC00178373-01, 1,4-dimethyl-7-(1-methylethyl)-azulene, AN-45261, AS-13972, CC-29080, CJ-04653, KB-52304, LS-23575, SMR001306801, ST098714, ZB015559, TL8003279, TR-017759, FT-0626818, G0228, V0215, 1,4-Dimethyl-7-(1-methyl)-azulene (azulon), 1,4-Dimethyl-7-(1-methylethyl)azulene, 9CI, C09675, D01037, A827639, C-30056, SR-05000002441, SR-05000002441-1, BRD-K36719159-001-04-9, I14-99343, Z56347227, 12040-47-0, InChI=1/C15H18/c1-10(2)13-7-5-11(3)14-8-6-12(4)15(14)9-13/h5-10H,1-4H

ID: 657

InChIKey: FWYSBEAFFPBAQU-LBPRGKRZSA-N
SMILES: CC(C)([C@@H]1CC2=C(O1)C=C3C(=C2)C=CC(=O)O3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 334704
synonyms found at PubChem are:
Marmesin, (+)-Marmesin, 13849-08-6, S-(+)-Marmesin, (7S)-marmesin, (S)-Marmesin, MARMESIN, (+)-, CHEBI:6695, CHEMBL442813, (2S)-2-(1-hydroxy-1-methylethyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one, (S)-2-(2-Hydroxypropan-2-yl)-2H-furo[3,2-g]chromen-7(3H)-one, (+)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one, (S)-(+)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one, (S)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one, (S)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one, S(+)-Marmesin, Spectrum_001516, SpecPlus_000918, AC1L7FYQ, Spectrum2_000737, Spectrum3_001642, Spectrum4_001701, Spectrum5_000402, BSPBio_003363, KBioGR_002022, KBioSS_001996, DivK1c_007014, SPBio_000694, MEGxp0_001933, 2-(1-Hydroxy-1-methylethyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one #, SCHEMBL12062107, KBio1_001958, KBio2_001996, KBio2_004564, KBio2_007132, KBio3_002583, ZINC51924, FWYSBEAFFPBAQU-LBPRGKRZSA-N, MolPort-002-321-244, HY-N2176, BDBM50250917, CCG-40145, NSC340840, AKOS021983162, CS-7901, MCULE-3509624985, MCULE-4926964615, NSC-340840, SDCCGMLS-0066759.P001, 7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-, C09276, AB00053150-02, BRD-K36377456-001-02-0, 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (+)-, 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-, (2S)-2-(2-hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one, 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-(+)-, (2S)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (+)-, 7H-Furo[3,2-g][1]benzopyran-7-one,2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (2S)-, NCGC00178117-02!(2S)-2-(2-hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one

ID: 658

InChIKey: FXKCQWIUITUJFU-UHFFFAOYSA-N
SMILES: CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 203135
synonyms found at PubChem are:
Chlortropbenzyl, FC-1, Tropine 4-chlorobenzhydryl ether hydrochloride, 3-CPMT, SL-6057, WY 2149, SL 6057, 1-alpha-H,5-alpha-H-Tropane, 3-alpha-((p-chloro-alpha-phenylbenzyl)oxy)-, hydrochloride, 3-alpha-((p-Chloro-alpha-phenylbenzyl)oxy)-1-alpha-H,5-alpha-H-tropane hydrochloride, CHEMBL540034, 14008-79-8, 4'-Chloro-3-alpha-(diphenylmethoxy)tropane hydrochloride, SCHEMBL466951, AC1L49W9, CTK8F5025, FXKCQWIUITUJFU-UHFFFAOYSA-N, MolPort-003-940-668, AKOS024458694, NCGC00093782-01, LS-157770, C-207, EU-0100344, SR-01000075361, SR-01000597868, J-007352, SR-01000075361-1, SR-01000597868-1, 3?-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride, 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride

ID: 659

InChIKey: FXNFHKRTJBSTCS-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281605
synonyms found at PubChem are:
baicalein, 491-67-8, 5,6,7-Trihydroxyflavone, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Noroxylin, Biacalein, BaiKalein, Baicelein, UNII-49QAH60606, NSC661431, NSC 661431, CHEMBL8260, 5,6,7-trihydroxy-2-phenylchromen-4-one, CHEBI:2979, FXNFHKRTJBSTCS-UHFFFAOYSA-N, IN1408, 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-, 49QAH60606, 5,7-Trihydroxyflavone, 5,6,7-trihydroxy-2-phenyl-chromen-4-one, 4H-1-Benzopyran-4-one,5,6,7-trihydroxy-2-phenyl-, Sho-saiko-to, 27462-75-5, SMR000112462, SR-01000597499, Baicalein, 8, Baicalein,(S), 3WL, Baicalein, 14, Baicalein, 98%, AC1NQYPP, Spectrum_000427, Tocris-1761, SpecPlus_000758, Spectrum2_000466, Spectrum3_001608, Spectrum4_000537, Spectrum5_001418, D00YEV, Oprea1_765614, BSPBio_003215, KBioGR_001173, KBioSS_000907, MLS002473007, MLS006011756, BIDD:ER0121, DivK1c_006854, SCHEMBL139617, SPECTRUM1504002, 5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one, SPBio_000572, GTPL5144, DTXSID2022389, KBio1_001798, KBio2_000907, KBio2_003475, KBio2_006043, KBio3_002435, MolPort-001-741-408, HMS1922O22, HMS2267F15, HMS3268C22, HMS3649O19, HMS3655P18, ALBB-028286, BCP14393, HY-N0196, TNP00121, ZINC3871633, BBL027840, BDBM50009001, CCG-38705, IN2067, LMPK12111095, MFCD00017459, NSC729192, s2268, SBB067246, STL146746, AKOS005747014, AC-7991, AN-8474, CS-6159, MCULE-8669340472, NSC-661431, NSC-729192, SDCCGMLS-0066744.P001, Baicalein, analytical reference material, SMP1_000037, NCGC00017236-01, NCGC00017236-02, NCGC00017236-03, NCGC00017236-04, NCGC00017236-05, NCGC00017236-06, NCGC00017236-07, NCGC00017236-08, NCGC00017236-10, NCGC00025282-01, NCGC00025282-02, NCGC00025282-03, NCGC00025282-04, NCGC00178204-01, KB-47494, LS-39842, SC-04798, SC-20654, ST057152, 5,6,7-Trihydroxy-2-phenyl-chroman-4-one, AB0018364, FT-0622548, N1858, Baicalein, disposable screening library format, C10023, S00113, W-2736, 491B678, 5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one, Q-100550, SR-01000597499-1, SR-01000597499-3, SR-01000597499-4, SR-01000597499-6, W-202870, 5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one, BRD-K72327355-001-02-2, BRD-K72327355-001-06-3

ID: 660

InChIKey: FXUAIOOAOAVCGD-WCTZXXKLSA-N
SMILES: C1C[C@H]([C@@H]2[C@@H]([C@@H](CN2C1)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 51683
synonyms found at PubChem are:
swainsonine, Tridolgosir, 72741-87-8, (-)-Swainsonine, Tridolgosir [INN], UNII-RSY4RK37KQ, RSY4RK37KQ, CHEBI:9367, CHEMBL371197, FXUAIOOAOAVCGD-WCTZXXKLSA-N, (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, NCGC00163481-02, (1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol, (1S,2R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,2,8-triol, 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-, SWA, Swainosine, Locoweed deriv., NSC614553, 1hww, Octahydro-1,2,8-indolizinetriol hydrochloride, AC1L1BJG, (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol, AC1Q1GU1, DSSTox_CID_26356, DSSTox_RID_81558, CBiol_001919, DSSTox_GSID_46356, BSPBio_001148, KBioGR_000488, KBioSS_000488, SCHEMBL765848, DTXSID5046356, KBio2_000488, KBio2_003056, KBio2_005624, KBio3_000895, KBio3_000896, MolPort-003-850-377, Bio1_000205, Bio1_000694, Bio1_001183, Bio2_000414, Bio2_000894, HMS1362J09, HMS1792J09, HMS1990J09, HMS3403J09, ZINC3875041, Tox21_112058, 2057AH, BDBM50168995, MFCD00017554, (1S,2R,8aR)-Octahydroindolizinetriol, AKOS016344385, CCG-208274, DB02034, NSC-614553, IDI1_002169, SMP1_000286, NCGC00163481-03, NCGC00163481-04, LS-83623, CAS-72741-87-8, B7316, BB 0261154, FT-0630815, C10173, (1S, 2R, 8R, 8AR)-1,2,8-Indolizidinetriol, 8|A,|A-Octahydroindolizidine-1|A,2|A,8|A-triol, SR-05000002325, SR-05000002325-2, (1S,2R,8R,8aR)-Octahydro-indolizine-1,2,8-triol, 1,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-, 1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)-, CFCE4066-9132-492F-B4E1-B50B974FE148, 1,2,8-Indolizinetriol, octahydro-, (1S-(1-alpha,2-alpha,8-beta,8a-beta))-, 1,8-Indolizinetriol, octahydro-,[1S-(1.alpha.,2.alpha., 8.beta.,8a.beta.)]-, SWS

ID: 661

InChIKey: FXYZDFSNBBOHTA-UHFFFAOYSA-N
SMILES: C1COCCN1C(=N)N=C(N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 76621
synonyms found at PubChem are:
Moroxydine hydrochloride, 3160-91-6, Moroxydine HCl, Flumidin, Virustat, Influcol, Spenitol, Virusmin, ABOB hydrochloride, Flumadon, N-Carbamimidoylmorpholine-4-carboximidamide hydrochloride, Moroxidine hydrochloride, Flumidin (VAN), Morpholinobiguanide hydrochloride, Moroxydine (hydrochloride), Morpholinobiguanide monohydrochloride, UNII-6Y9698W0XT, 4-(Amidinoamidino)morpholine, hydrochloride, EINECS 221-612-6, NSC 43840, NSC 47838, NSC 52355, NSC 63755, NSC 407204, AI3-51320, N-[amino(imino)methyl]morpholine-4-carboximidamide hydrochloride, 6Y9698W0XT, 4-Morpholinecarboxamidine, N-amidino-, monohydrochloride, N1,N1-Anhydrobis(beta-hydroxyethyl)biguanide hydrochloride, Biguanide, 1,1-anhydrobis(beta-hydroxyethyl)-, hydrochloride, 4-Morpholinecarboximidamide, N-(aminoiminomethyl)-, monohydrochloride, N(sup 1),N(sup 1)-Anhydrobis(beta-hydroxyethyl)biguanide hydrochloride, DSSTox_CID_25376, DSSTox_RID_80837, DSSTox_GSID_45376, 1-(morpholine-4-carboximidoyl)guanidine hydrochloride, 3731-59-7 (Parent), assur, SMR000718626, 4-Morpholinecarboxamidine, monohydrochloride, SR-01000841820, NCGC00016623-01, CAS-3160-91-6, amino(iminomorpholin-4-ylmethyl)carboxamidine, chloride, N-carbamimidoylmorpholine-4-carboximidamide;hydrochloride, N1,N1-Anhydrobis(.beta.-hydroxyethyl)biguanide hydrochloride, Prestwick_547, EINECS 231-039-3, virustat hydrochloride, N-Amidinomorpholine-4-carboxamidine HCl, Moroxydine,hydrochloride, ACMC-1BCAT, AC1Q3CFW, moroxydine monohydrochloride, C6H14ClN5O, AC1L2RB4, C6H13N5O.HCl, N-Amidinomorpholine-4-carboxamidine hydrochloride, SCHEMBL92735, Moroxydine Hydrochloride,(S), MLS001032033, MLS002154194, Moroxydine hydrochloride, 99%, Morpholinbiguanide Hydrochloride, CHEMBL1874337, DTXSID1045376, SCHEMBL14973476, CTK8C5518, HY-B0420A, FXYZDFSNBBOHTA-UHFFFAOYSA-N, MolPort-002-506-667, MolPort-006-836-134, HMS1568A10, Pharmakon1600-01506078, 1-Morpholinobiguanide Hydrochloride, KS-00000GO9, NSC43840, NSC47838, NSC52355, NSC63755, Tox21_110532, NSC-43840, NSC-47838, NSC-52355, NSC-63755, NSC407204, NSC759315, s2486, SBB009855, AKOS005256937, Tox21_110532_1, API0000667, CCG-213951, CS-2526, GL-0672, NSC-407204, NSC-759315, TRA0011334, VA11325, VA11326, KS-00001P37, NCGC00016623-05, 7420-18-0, AC-14457, AK162412, AS-13339, H933, LS-92555, SC-13975, SC-18646, ST060170, AB0013368, AB1009433, AB2000592, AX8140384, TR-015161, FT-0698221, M2443, ST24048531, EN300-216965, M-2138, 160M916, A823597, J-018491, SR-01000841820-2, SR-01000841820-3, I14-18788, N-(morpholine-4-carboximidoyl)guanidine hydrochloride, N''-(morpholine-4-carboximidoyl)guanidine hydrochloride, Z2160887313, N-(Aminoiminomethyl)-4-morpholinecarboximidamide hydrochloride, N-(diaminomethylidene)-4-morpholinecarboximidamide hydrochloride, N-(diaminomethylidene)morpholine-4-carboximidamide hydrochloride, 4-Morpholinecarboximidamide, N-(aminoiminomethyl)-,monohydrochloride, N-[bis(azanyl)methylidene]morpholine-4-carboximidamide hydrochloride, 4-Morpholinecarboximidamide, N-(aminoiminomethyl)-, monohydrochloride (9CI), 1195550-67-4, 8058-46-6, MolPort-000-745-489, MCULE-6852238035, AKOS015917943, I14-8679

ID: 662

InChIKey: FYBXRCFPOTXTJF-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 40127
synonyms found at PubChem are:
carteolol hydrochloride, 51781-21-6, Carteolol HCl, Arteoptic, Mikelan, Abbott-43326, Cartrol, Endak, Endak hydrochloride, Ocupress, Carbonolol, Endak mite, Abbott 43326, OPC-1085, Teoptic, Carteolol (hydrochloride), OPC 1085, EINECS 257-415-7, dl-Carteolol Hydrochloride, NSC 300906, Ocupress (TN), Cartrol (TN), 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril hydrochloride, 5-(3-tert-Butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyril hydrochloride, 5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1H)-quinolinone hydrochloride, 5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydrocarbostyril monohydrochloride, 5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1H)-chinolinon-hydrochlorid [German], DSSTox_CID_25478, DSSTox_RID_80904, DSSTox_GSID_45478, CHEBI:3438, 5-(3-((tert-Butyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2-quinolone monohydrochloride, 2(1H)-Quinolinone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, monohydrochloride, 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, monohydrochloride, 5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone Hydrochloride, 5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1H)-chinolinon-hydrochlorid, Arteolol, Carteol, Mikelan LA, 5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydrocarbostyril monohydrochloride, Carteolol hydrochloride [USAN:JAN], Carteolol hydrochloride [USAN:USP:JAN], 5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydroquinolin-2(1H)-one hydrochloride, Carteolol(hydrochloride), NCGC00016865-01, CAS-51781-21-6, SCHEMBL41380, MLS002153816, C16H24N2O3.HCl, Carteolol Hydrochloride ,(S), (+/-)-Carteolol Hydrochloride, CHEMBL1201002, DTXSID4045478, CTK8F8480, MolPort-006-129-555, HMS1569I14, Pharmakon1600-01505519, 51781-06-7 (Parent), AC1L2343, BCP28338, EX-A1257, KS-00001D9M, Tox21_110654, Carteolol hydrochloride (JP17/USP), HY-17495A, NSC300906, NSC760060, s4278, AKOS027379166, Tox21_110654_1, CCG-213475, CS-2955, NSC-300906, NSC-760060, NCGC00179541-03, CC-05270, SMR001233186, LS-142780, B5944, FT-0640026, D00599, WLN: T66 BMVT&J GO1YQ1MX1&1&1 &GH, C-35682, SR-01000841202, SR-01000841202-2, 5-(3-t-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyril hydrochloride, 2(1H)-Quinolinone,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-, monohydrochloride, 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinolin-2-one hydrochloride, 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one hydrochloride, 2(1H)-Quinolinone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-,monohydrochloride, 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro, monohydrochloride, 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2hydroxypropoxy]-3,4-dihydro, monohydrochloride, AKOS026750076, 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one hydrochloride, N-tert-butyl-2-hydroxy-3-[(2-oxo-1,2,3,4-tetrahydroquinolin-5-yl)oxy]propan-1-aminium chloride

ID: 663

InChIKey: FYDVPEVHFUBOJG-UHFFFAOYSA-N
SMILES: C1OC2=C(O1)C=C(C=C2)CC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 97807
synonyms found at PubChem are:
SAFROLGLYCOL, 7154-01-0, 1,2-Propanediol, 3-(1,3-benzodioxol-5-yl)-, 3-(Benzo[d][1,3]dioxol-5-yl)propane-1,2-diol, 3-(1,3-benzodioxol-5-yl)-1,2-propanediol, 3-(3,4-Methylenedioxyphenyl)-1,2-propanediol, 3-(2H-1,3-benzodioxol-5-yl)propane-1,2-diol, (+)-3-(3,4-Methylenedioxyphenyl)-1,2-propanediol, NSC43297, NSC 43297, 2',3'-Dihydro-2',3'-dihydroxysafrole, Spectrum_000901, SpecPlus_000090, AI3-20686, AC1L3ZAL, AC1Q6ZXS, AC1Q7BPP, Spectrum2_000683, Spectrum3_000113, Spectrum4_000935, Spectrum5_001785, BSPBio_001726, KBioGR_001490, KBioSS_001381, SPECTRUM100577, DivK1c_006186, 1,2-Propanediol, 3-(3,4-(methylenedioxy)phenyl)-, SPBio_000805, MEGxp0_001786, CHEMBL1527944, SCHEMBL11447270, ACon1_002342, CHEBI:91667, CTK2H7770, KBio1_001130, KBio2_001381, KBio2_003949, KBio2_006517, KBio3_000866, MolPort-001-742-534, CCG-38575, NSC-43297, 1, 3-(1,3-benzodioxol-5-yl)-, AKOS022184763, WLN: T56 BO DO CHJ G1YQ1Q, MCULE-1341874849, SDCCGMLS-0066370.P001, 1, 3-[3,4-(methylenedioxy)phenyl]-, NCGC00095438-01, NCGC00095438-02, NCGC00095438-03, 4CN-2553, ST24041531, 3-(1,3-benzodioxol-5-yl)propane-1,2-diol, SR-05000002431, SR-05000002431-1, BRD-A37867643-001-01-7

ID: 664

InChIKey: FYEHYMARPSSOBO-UHFFFAOYSA-N
SMILES: C1=CC(=O)C=CC1=C(C2=CC=C(C=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5100
synonyms found at PubChem are:
Aurin, rosolic acid, Corallin, 603-45-2, p-Rosolic acid, Aurine, Spirit Aurine, Corallin Spirit Soluble, 4,4'-Dihydroxyfuchsone, Aurin No. 555, C.I. 43800, 4-(Bis(4-hydroxyphenyl)methylene)cyclohexa-2,5-dienone, Pararosolic Acid, UNII-85N4AK3JAU, NSC 7805, 4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one, 85N4AK3JAU, 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]-, CHEBI:34544, NSC7805, C19H14O3, 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one, CI-43800, 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, 2,5-Cyclohexadien-1-one, 4-(bis(4-hydroxyphenyl)methylene)-, SMR001224399, ROSOLICACID, Corallin yellow, p-rosolic acin, EINECS 210-041-8, Rosolic acid 25g, Spectrum_000988, AI3-18245, Spectrum2_000762, Spectrum3_000609, Spectrum4_000904, Spectrum5_001864, AC1L1JM0, AC1Q69YI, Corallin yellow (Salt/Mix), p-Rosolic acid, 85.0%, BSPBio_002118, CORALLIN (FREE ACID), KBioGR_001368, KBioSS_001468, MLS001359834, MLS002695900, BIDD:ER0176, DivK1c_000400, SCHEMBL590856, SPECTRUM1500762, SPBio_000804, CHEMBL210868, DTXSID2022387, HMS501D22, KBio1_000400, KBio2_001468, KBio2_004036, KBio2_006604, KBio3_001618, FYEHYMARPSSOBO-UHFFFAOYSA-N, MolPort-003-666-326, NINDS_000400, 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one, HMS1923K11, HMS3058N04, p-Rosolic acid, JIS special grade, KS-00000X6Y, NSC-7805, ZINC3874879, p-Rosolic acid (C.I. 43800), p-Rosolic acid, Dye content 85 %, BDBM50427512, CCG-39006, MFCD00001624, SBB058277, STL453788, AKOS015903417, MCULE-1450942647, 2, 4-[bis(p-hydroxyphenyl)methylene]-, IDI1_000400, SMP1_000134, 2, 4-[bis(4-hydroxyphenyl)methylene]-, NCGC00095266-01, NCGC00095266-02, NCGC00095266-03, AJ-46406, AN-21594, NCI60_041721, ST080685, Aurin (p-Rosolic acid) (C.I. 43800), TR-031574, A0598, ST24043040, A-8703, C14213, BRD-K24453427-001-02-9, BRD-K24453427-001-04-5, I14-19309, 4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one, 2,5-Cyclohexadien-1-one, 4-(bis(p-hydroxyphenyl)methylene)-, 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one #, 2,5-Cyclohexadien-1-one, 4-(bis(p-hydroxyphenyl)methylene)- (8CI)

ID: 665

InChIKey: FYEMNIIBXSJOLP-UHFFFAOYSA-N
SMILES: CC(C)NNC(=O)C1=CC=NC=C1.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5702132
synonyms found at PubChem are:
IPRONIAZID SULFATE, NCGC00094820-01, DSSTox_CID_25852, DSSTox_RID_81174, DSSTox_GSID_45852, CAS-36504-56-0, AC1NWAR7, SPECTRUM1500634, CHEMBL1534878, DTXSID8045852, SCHEMBL15200763, HMS500G03, HMS1921M11, Pharmakon1600-01500634, Tox21_111341, CCG-39720, NSC757380, Tox21_111341_1, NSC-757380, NCGC00015565-06, NCGC00094820-02, NCGC00094820-03, SR-01000075585-6, N'-propan-2-ylpyridine-4-carbohydrazide; sulfuric acid, 36504-56-0

ID: 666

InChIKey: FYPMFJGVHOHGLL-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4912
synonyms found at PubChem are:
probucol, Lorelco, 23288-49-5, Biphenabid, Bisphenabid, Lurselle, Bisbid, Lesterol, Lursell, Panavir, DH-581, Probucolum, Sinlestal, Probucolum [INN-Latin], DH 581, Superlipid, Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, 4,4'-(Isopropylidenedithio)bis(2,6-di-tert-butylphenol), UNII-P3CTH044XJ, NSC 86225, NSC 652160, Acetone, bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, CCRIS 7510, Probucol [USAN:BAN:INN:JAN], C31H48O2S2, LORELCO (TN), EINECS 245-560-9, CHEMBL608, BRN 2026253, P3CTH044XJ, MLS000028492, CHEBI:8427, FYPMFJGVHOHGLL-UHFFFAOYSA-N, 4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol), NSC86225, ZERO/001429, 4,4'-[(1-Methylethylidene)bis(thio)]bis-[2,6-bis(1,1-dimethylethyl)phenol], NSC652160, 2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol, DE-3872, 4,4'-(Isopropylidenedithio)bis(2, 6-di-tert-butylphenol), 4,4'-(Isopropylidenedithio)bis[2, 6-di-tert-butylphenol], 4,4'-(Isopropylidenedithio)bis[2,6-di-tert-butylphenol], NCGC00016777-01, Acetone, bis (3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, SMR000058265, CAS-23288-49-5, 4,4'-(propane-2,2-diylbis(sulfanediyl))bis(2,6-di-tert-butylphenol), Phenol, 4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-, DSSTox_CID_25440, DSSTox_RID_80881, DSSTox_GSID_45440, 2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol, W-107409, 4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol), 4,4'- (Isopropylidenedithio)bis(2, 6-di-tert-butylphenol), 2,6-bis(tert-butyl)-4-{1-[3,5-bis(tert-butyl)-4-hydroxyphenylthio]-isopropylth io}phenol, Phenol, 4,4'-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-, SR-01000695447, phenbutol, Serterol, DH581, Probucol,(S), Prestwick_408, Probucol [USAN:USP:INN:BAN:JAN], PubChem17621, Spectrum_001296, Opera_ID_1820, Prestwick0_000384, Prestwick1_000384, Prestwick2_000384, Prestwick3_000384, Spectrum2_001400, Spectrum3_001438, Spectrum4_000414, Spectrum5_001343, Aventis Brand of Probucol, Hoechst Brand of Probucol, Almirall Brand of Probucol, D0H2DQ, SCHEMBL4150, Probucol (JAN/USP/INN), BSPBio_000567, BSPBio_003176, KBioGR_000708, KBioGR_002394, KBioSS_001776, KBioSS_002399, Probucol, analytical standard, DivK1c_000599, SPECTRUM1501109, Probucol (JP17/USP/INN), SPBio_001420, SPBio_002488, AC1L1J88, BPBio1_000625, GTPL7277, DTXSID2045440, CTK8G2582, HMS501N21, KBio1_000599, KBio2_001776, KBio2_002394, KBio2_004344, KBio2_004962, KBio2_006912, KBio2_007530, KBio3_002396, KBio3_002873, KS-00000XMC, cMAP_000039, MolPort-002-042-265, NINDS_000599, HMS1569M09, HMS1921D21, HMS2092D05, HMS2096M09, HMS2233C08, HMS3655P19, HMS3713M09, Pharmakon1600-01501109, BCP06487, HY-B0388, ZINC1530755, Tox21_110605, BDBM50007260, BG0666, CCG-38986, MFCD00079281, NSC-86225, NSC757837, s2119, SBB001675, STK762566, AKOS001740866, Tox21_110605_1, API0003932, CS-2473, DB01599, KS-1459, MCULE-4445301513, NSC-652160, NSC-757837, IDI1_000599, Phenol, 4,4'-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl))-, NCGC00016777-02, NCGC00016777-03, NCGC00016777-04, NCGC00016777-05, NCGC00016777-07, NCGC00016777-08, NCGC00094895-01, NCGC00094895-02, NCGC00094895-03, NCGC00094895-04, CC-33926, CJ-24018, LS-13188, SC-47042, ST075698, SBI-0051640.P002, AB2000521, AB00052202, FT-0630498, P2002, C07373, D00476, S-8042, AB00052202_14, AB00052202_15, 288P495, C-23041, Acetone,5-di-tert-butyl-4-hydroxyphenyl) mercaptole, SR-01000695447-2, SR-01000695447-3, BRD-K72029282-001-04-8, BRD-K72029282-001-15-4, I14-31835, Acetone bis(3,5-di-t-butyl-4-hydroxyphenyl) mercaptole, Z1551900339, Probucol, United States Pharmacopeia (USP) Reference Standard, Phenol,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-, 2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol, 4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol], 2,6-di(tert-butyl)-4-[(1-{[3,5-di(tert-butyl)-4-hydroxyphenyl]sulfanyl}-1-methylethyl)sulfanyl]phenol, 2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol, 2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol), 2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol, 2,6-Ditert-butyl-4-((1-[(3,5-ditert-butyl-4-hydroxyphenyl)sulfanyl]-1-methylethyl)sulfanyl)phenol #, 2,6-ditert-butyl-4-[1-(3,5-ditert-butyl-4-hydroxy-phenyl)sulfanyl-1-methyl-ethyl]sulfanyl-phenol

ID: 667

InChIKey: FZERHIULMFGESH-UHFFFAOYSA-N
SMILES: CC(=O)NC1=CC=CC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 904
synonyms found at PubChem are:
acetanilide, N-Phenylacetamide, 103-84-4, Acetanil, Acetamidobenzene, Antifebrin, Acetylaniline, Acetanilid, N-Acetylaniline, Acetamide, N-phenyl-, Acetic acid anilide, Acetoanilide, Phenalgene, Acetylaminobenzene, Phenalgin, Aniline, N-acetyl-, N-acetylarylamine, Benzenamine, N-acetyl-, USAF EK-3, NSC 7636, AN [Analgesic], Caswell No. 003E, Ethananilide, UNII-SP86R356CC, N-Phenyl-acetamide, N-Acetylaminobenzene, Acetic acid amide, N-phenyl-, CCRIS 4452, HSDB 2665, Acetanilide (Antifebrin), EINECS 203-150-7, C8H9NO, AI3-01045, SP86R356CC, CHEBI:28884, NSC7636, FZERHIULMFGESH-UHFFFAOYSA-N, N-Phenylacetamide;N-Phenylacetamide, NCGC00091326-01, DSSTox_CID_2543, DSSTox_RID_76620, DSSTox_GSID_22543, N-Phenylacetamide (Acetanilide), Acetamide, N-(phenyl-d5)-, n-phenylacetamid, Acetanilide [NF], CAS-103-84-4, SMR001306799, PhNHAc, N-phenyl acetamide, Acetanilide, 99%, Spectrum_000178, AC1L1AAE, Spectrum2_001434, Spectrum3_000935, Spectrum4_001034, Spectrum5_000989, WLN: 1VMR, ACMC-1AR90, Ethanimidic acid, N-phenyl-, SCHEMBL24681, KBioGR_001587, KBioSS_000658, Acetanilide, 98% 100g, KSC492K1L, MLS002207284, MLS002415707, DivK1c_000073, SPECTRUM1501173, SPBio_001568, AC1Q5N69, ARONIS003513, CHEMBL269644, DTXSID2022543, SCHEMBL14255226, Acetanilide, LR, >=98.5%, CTK3B8627, CTK3J2515, HMS500D15, KBio1_000073, KBio2_000658, KBio2_003226, KBio2_005794, KBio3_001970, KS-00003WHS, MolPort-000-564-428, NINDS_000073, ACETANILIDE (RING-13C6), ACETIC ACID,AMIDE,N-PHENYL, BCPP000440, HMS1921N07, HMS2092J11, HMS2234E18, HMS3374L04, HMS3651D07, Pharmakon1600-01501173, ZINC142824, BCP02363, NSC-7636, Tox21_111113, Tox21_200925, ANW-74570, CCG-38984, LS-366, MFCD00008674, NSC757879, s2538, SBB040833, STK046402, AKOS000121114, AKOS030596060, Tox21_111113_1, BCP9000226, MCULE-1268638727, NE10600, NSC-757879, RTR-000889, TRA0025008, Acetanilide, NIST(R) SRM(R) 141d, IDI1_000073, KS-00000W21, NCGC00091326-02, NCGC00091326-03, NCGC00091326-04, NCGC00091326-06, NCGC00258479-01, 55576-55-1, AJ-12477, AN-24658, AS-13389, CJ-01073, I054, SC-78966, ST040202, ZB004945, SBI-0051673.P002, AB2000635, KB-259064, KB-294800, ST2419721, TR-000889, 795-EP2269979A1, 795-EP2277880A1, 795-EP2288595A2, 795-EP2292610A1, 795-EP2296664A1, 795-EP2298729A1, 795-EP2308872A1, 795-EP2316829A1, B2071, CS-0010112, FT-0621730, FT-0621731, 1947-EP2275407A1, 1947-EP2298752A1, 1947-EP2301918A1, C07565, AB00052235_07, AB00052235_08, Acetanilide, purified by sublimation, >=99.9%, Acetanilide, puriss. p.a., >=99.5% (CHN), AH-034/32461060, SR-05000001777, I01-2061, Q-200578, SR-05000001777-1, BRD-K11094367-001-04-4, F0808-0907, Acetanilide, zone-refined, purified by sublimation, >=99.95%, Acetaminophen Related Compound D, United States Pharmacopeia (USP) Reference Standard, Acetanilide Melting Point Standard, United States Pharmacopeia (USP) Reference Standard, InChI=1/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10, N-phenylacetamide;Acetanil;Acetamidobenzene;Acetylaniline;NSC 7636;Antifebrin, 88070-49-9, Acetanilide (Acetaminophen Related Compound D), Pharmaceutical Secondary Standard; Certified Reference Material, Acetanilide melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 668

InChIKey: FZHKNEWQWRWDJI-UHFFFAOYSA-N
SMILES: CC1=C(N=CC=C1)NC2=NC(=CS2)C3=CC(=C(C=C3)OC)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "O Zegarra-Moran" "LJ Galietta" "GL Lukacs" "K Du" "AS Verkman" "N Pedemonte"

CID is 4416391
synonyms found at PubChem are:
AC1N9U4M, Oprea1_174232, SCHEMBL838280, MolPort-008-345-333, ZINC6391717, STK947466, AKOS005641136, MCULE-1699686726, EU-0013908, 4-(4-methoxy-3-methylphenyl)-N-(3-methylpyridin-2-yl)thiazol-2-amine, [4-(4-Methoxy-3-methyl-phenyl)-thiazol-2-yl]-(3-methyl-pyridin-2-yl)-amine, 4-(4-methoxy-3-methylphenyl)-N-(3-methylpyridin-2-yl)-1,3-thiazol-2-amine, N-[4-(4-methoxy-3-methylphenyl)-1,3-thiazol-2-yl]-3-methylpyridin-2-amine

ID: 669

InChIKey: GAAKALASJNGQKD-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCC2=CC=C(C=C2)N)C3=CC=CC(=C3)C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 121930
synonyms found at PubChem are:
PAPP, p-NH2-PE-Tfmpp, LY-165163, LY-165,163, UNII-8HAJ699EWG, 1814-64-8, LY 165163, 8HAJ699EWG, 4-[2-[4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]aniline, 1-(2-(4-Aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine, 4-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)aniline, LY 165,163, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine, Benzenamine, 4-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-, NSC628235, C19H22F3N3, Lopac-S-009, Biomol-NT_000160, D0T4PS, GTPL18, AC1L3TO7, AC1Q4K3D, Lopac0_001132, MLS000859974, LY-165,163, solid, BPBio1_000375, SCHEMBL3976547, CHEMBL1256693, CHEBI:92250, CTK8D5097, DTXSID30171136, HMS2232I03, HMS3263D05, HMS3369D03, ZINC1619831, Tox21_501132, MFCD00055098, AKOS030547154, CCG-205206, LP01132, NCGC00015907-01, NCGC00015907-02, NCGC00015907-03, NCGC00015907-04, NCGC00015907-05, NCGC00094399-01, NCGC00094399-02, NCGC00094399-03, NCGC00261817-01, NCI60_009079, SMR000326833, LS-173712, EU-0101132, S-009, SR-01000075576, J-011585, SR-01000075576-1, BRD-K14282469-001-01-5, PAPP (LY-165,163) SELECTIVE 5-HT1A SERO, LY-165,163; p-Aminophenethyl-m-trifluoromethylphenyl piperazine

ID: 670

InChIKey: GAAOKTBHSXYRNH-UHFFFAOYSA-N
SMILES: CCN(CCCl)CC1=CC=CC=C1C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 42604
synonyms found at PubChem are:
AC1L2867, 2-chloroethyl-ethyl-[(2-methylphenyl)methyl]azanium chloride, Xylamine hydrochloride, 57913-68-5, n-(2-chloroethyl)-n-ethyl-2-methylbenzylamine hydrochloride, N-(2-Chloroethyl)-N-ethyl-2-methylbenzylamine, N-CHLOROETHYL-N-ETHYL-2'-METHYLBENZYLAMINE HYDROCHLORIDE, CHEMBL1355604, CTK8G3796, DTXSID60587867, CCG-39198, NCGC00094936-01, KB-309386, FT-0746088, C-48816, 2-chloro-N-ethyl-N-(2-methylbenzyl)ethanamine hydrochloride, (2-chloroethyl)(ethyl)[(2-methylphenyl)methyl]amine hydrochloride, 2-Chloro-N-ethyl-N-[(2-methylphenyl)methyl]ethan-1-amine--hydrogen chloride (1/1)

ID: 671

InChIKey: GADIKQPUNWAMEB-UHFFFAOYSA-N
SMILES: CCC1=C2C3=CC(=C(C=C3NC2=CN=C1C(=O)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 104999
synonyms found at PubChem are:
DMCM, 82499-00-1, Methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate, UNII-1309288N1J, CHEMBL17468, METHYL-6,7-DIMETHOXY-4-ETHYL-BETA-CARBOLINE-3-CARBOXYLATE, methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate, 1309288N1J, Methyl 4-ethyl-6,7-dimethoxy-9H-pyrido(3,4-b)indole-3-carboxylate, 4-Ethyl-6,7-dimethoxy-9H-pyrido(3,4-b)indole-3-carboxylic acid, methyl ester, 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 4-ethyl-6,7-dimethoxy-, methyl ester, C17H18N2O4, Lopac-E-007, Biomol-NT_000249, D0GQ1S, AC1L2XV2, AC1Q5ZP9, Lopac0_000543, SCHEMBL472510, BPBio1_001013, GTPL4179, BDBM81951, CHEBI:92263, GADIKQPUNWAMEB-UHFFFAOYSA-N, methyl 4-ethyl-6,7-dimethoxy-9h-|A-carboline-3-carboxylate, ZINC2516023, BDBM50065229, PDSP1_001756, PDSP1_001780, PDSP2_001739, PDSP2_001763, AKOS015897178, CAS_104999, CCG-204633, NSC_104999, KS-0000003O, NCGC00015392-01, NCGC00015392-02, NCGC00015392-03, NCGC00015392-04, NCGC00093931-01, NCGC00093931-02, NCGC00093931-03, LS-133444, E-007, EU-0100543, SR-01000075869, I07-0311, SR-01000075869-1, BRD-K14844937-001-01-6, 4-Ethyl-6,7-dimethoxy-9H-carbazole-3-carboxylic acid methyl ester, 4-Ethyl-6,7-dimethoxy-9H-beta-carboline-3-carboxylic acid methyl ester, 4-Ethyl-6,7-dimethoxy-9H-beta-carboline-3-carboxylic acid methyl ester(DMCM)

ID: 672

InChIKey: GAMKNLFIHBMGQT-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 363417
synonyms found at PubChem are:
palmitoyl-dl-carnitine chloride, 6865-14-1, (+/-)-Palmitoylcarnitine chloride, MLS002153285, 3-carboxy-n,n,n-trimethyl-2-(palmitoyloxy)propan-1-aminium chloride, Palmitoyl-DL- carnitine chloride, P-1100, P-1105, CHEMBL1256761, NSC628323, SR-01000076069, C23H46NO4.Cl, Palmitoylcarnitine chlorid, DL-Palmitoyl carnitine HCl, Palmityl dl-carnitine chloride, Palmitoyl carnitine hydrochloride, O-Palmitoyl-dl-carnitine chloride, NSC 628323, AC1Q1SGU, AC1L7MO9, BMK1-F9, SCHEMBL515545, PALMITOYL-DL-CARNITINE Cl, MolPort-003-983-794, HMS2232I17, HMS3262N18, HMS3266B11, HMS3370O16, Tox21_500948, 7612AH, BS0142, 3-Carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-1-propanaminium chloride, AKOS024284765, Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, palmitate, (+-)-, CCG-222252, LP00948, MCULE-1423669260, NSC-628323, 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, chloride, NCGC00094252-01, NCGC00261633-01, SMR000326758, ST079282, EU-0100948, A-8734, P 4509, SR-01000076069-1, SR-01000076069-3, 3-hexadecanoyloxy-4-(trimethylamino)butanoic acid, chloride, (2-hexadecanoyloxy-4-hydroxy-4-oxobutyl)-trimethylazanium chloride, 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-,chloride(1:1), 127719-10-2, 52234-80-7, 6819-24-5, 68960-79-2

ID: 673

InChIKey: GAPWCQHXCIXKLV-WXPPGMDDSA-N
SMILES: CC1=C2CC=C3[C@](C2=CC(=C1O)O)(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)OC)C)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 24861846
synonyms found at PubChem are:
PRISTIMEROL, CHEMBL56163, SCHEMBL12998329, (2R,4aS,6aS,6aS,14aS,14bR)-10,11-dihydroxy-2,4a,6a,6a,9,14a-hexamethyl-3,4,5,6,8,13,14,14b-octahydro-1H-picene-2-carboxylic acid methyl ester

ID: 674

InChIKey: GAQAKFHSULJNAK-UHFFFAOYSA-N
SMILES: CCOC(=O)NC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)CCN4CCOCC4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 34632
synonyms found at PubChem are:
MORICIZINE HYDROCHLORIDE, Moracizine hydrochloride, Ethmozine, Ethmosine, 29560-58-5, Ethmozin, Etmozin, Moricizine HCl, UNII-71OK3Z1ESP, 71OK3Z1ESP, MLS000830274, Moricizine hydrochloride [USP], EN 313, moracizine HCl, SMR000036736, Ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate hydrochloride, Ethyl 10-(beta-N-morpholinylpropionyl)phenothiazine-2-carbamate hydrochloride, DSSTox_CID_27766, DSSTox_RID_82543, Ethyl ether of 10-(beta-morpholylpropionyl)phenthiazinecarbamino acid hydrochloride, DSSTox_GSID_47786, (10-(3-(4-Morpholinyl)-1-oxopropyl)-10H-phenothiazin-2-yl)carbamic acid, ethyl ester, monohydrochloride, Moricizine hydrochloride (USP), Ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate, hydrochloride, Phenothiazine-2-carbamic acid, 10-(3-morpholinopropionyl)-, ethyl ester, hydrochloride, CHEBI:60937, Carbamic acid, (10-(3-(4-morpholinyl)-1-oxopropyl)-10H-phenothiazin-2-yl)-, ethyl ester, monohydrochloride, Carbamic acid, (10-(3-(4-morpholinyl)-l-oxopropyl)-10H-phenothiazin-2yl)-, ethyl ester, hydrochloride, CAS-29560-58-5, NCGC00016809-01, NCGC00016809-07, Ethmozine (TN), Opera_ID_267, AC1Q3EDS, AC1L1RZ0, Cambridge id 5229972, SCHEMBL41358, MLS000080120, REGID_for_CID_34632, CHEMBL1200334, DTXSID1047786, GAQAKFHSULJNAK-UHFFFAOYSA-N, MolPort-000-917-706, HMS1571C04, ethyl 10-(3-morpholinopropanoyl)-, Tox21_110622, AKOS030506898, Tox21_110622_1, API0003427, CCG-221051, VA11324, ACM29560585, NCGC00180924-01, CC-31001, LS-105268, E-313, E-350, FT-0630550, D02087, SR-01000614327, SR-01000614327-4, ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate hydrochloride, ethyl-[10-(3-morpholin-4-ylpropanoyl)-10h-phenothiazin-2-yl]carbamathydrochlorid, Carbamic acid, N-(10-(3-(4-morpholinyl)-1-oxopropyl)-10H-phenothiazin-2-yl)-, ethyl ester, hydrochloride (1:1), AC1LCXWF, ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate; hydron; chloride, MolPort-000-704-120, AKOS024357574, MCULE-2107794795, ST50985948, ethoxy-N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carboxamide, chlorid e, ethyl {10-[3-(morpholin-4-yl)propanoyl]-10HH-phenothiazin-2-yl}carbamate hydrochloride, 4-(3-{2-[(ethoxycarbonyl)amino]-10H-phenothiazin-10-yl}-3-oxopropyl)morpholin-4-ium chloride

ID: 675

InChIKey: GBABOYUKABKIAF-UHFFFAOYSA-N
SMILES: CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5672
synonyms found at PubChem are:
Vinorelbine base, 71486-22-1, AC1L1KVK, CHEBI:93786, CTK8G3751, STL450984, AKOS030228758, AN-6508, I06-0084, I06-0085, methyl 4-(acetyloxy)-15-[4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate

ID: 676

InChIKey: GBVCHRDRVDOMQV-RTWAWAEBSA-N
SMILES: CC(=CCC1=C(C=CC2=C1O[C@@H]3COC4=CC(=C(C=C4[C@@H]3C2=O)OC)OC)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708539
synonyms found at PubChem are:
Rotenonic acid, KBio2_001127, Spectrum_000647, SpecPlus_000073, AC1O8FCI, Spectrum2_000396, Spectrum3_000195, Spectrum4_001512, Spectrum5_000303, BSPBio_001749, KBioGR_002203, KBioSS_001127, SPECTRUM200851, DivK1c_006169, SCHEMBL752362, SPBio_000611, CHEMBL2181295, CHEBI:92599, KBio1_001113, KBio2_003695, KBio2_006263, KBio3_001249, GBVCHRDRVDOMQV-RTWAWAEBSA-N, CCG-38667, SDCCGMLS-0066410.P001, BRD-K34330170-001-01-8, (6aS,12aS)-9-Hydroxy-2,3-dimethoxy-8-(3-methyl-2-butenyl)-6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one, (6aS,12aS)-9-hydroxy-2,3-dimethoxy-8-(3-methylbut-2-enyl)-6a,12a-dihydro-6H-chromeno[3,4-b]chromen-12-one

ID: 677

InChIKey: GBWVAAKKEIOROG-UHFFFAOYSA-N
SMILES: CC(C(=O)O)NC(=O)C(CCSC)NC=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4363
synonyms found at PubChem are:
N-formylmethionylalanine, N-Formyl-Met-Ala, KBio2_004238, Spectrum_001190, AC1L1HZV, Spectrum2_001060, Spectrum3_001519, Spectrum4_000055, Spectrum5_001229, BSPBio_003197, KBioGR_000549, KBioSS_001670, MLS002207228, DivK1c_000925, SPBio_001020, SCHEMBL4287202, CHEMBL2130597, CHEBI:91785, HMS502O07, KBio1_000925, KBio2_001670, KBio2_006806, KBio3_002697, DTXSID10274432, NINDS_000925, CCG-40124, IDI1_000925, N-Formyl-Met-Ala, >=95% (HPLC), NCGC00178212-01, SMR001306773, 2-[(2-formamido-4-methylsulfanylbutanoyl)amino]propanoic acid

ID: 678

InChIKey: GCZZOZBWAZHCAN-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC(=S)NC2=NC=CS2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1395
synonyms found at PubChem are:
1-phenyl-3-(2-thiazolyl)-2-thiourea, 14901-16-7, Thiourea, N-phenyl-N'-2-thiazolyl-, 1-Phenyl-3-(2-thiazolyl)thiourea, PHENYLTHIAZOLYLTHIOUREA, 1-Phenyl-3-(thiazol-2-yl)thiourea, Urea, 1-phenyl-3-(2-thiazolyl)-2-thio-, MLS000766102, U 14624, 1-phenyl-3-(1,3-thiazol-2-yl)thiourea, Thiourea,N-phenyl-N'-2-thiazolyl-, EINECS 238-970-4, NSC 139257, BRN 0789556, 1-Phenyl-3-thiazol-2-yl-thiourea, NSC139257, NSC-139257, SMR000528602, U-14,624, (phenylamino)(1,3-thiazol-2-ylamino)methane-1-thione, Prestwick_76, AC1LEX1Z, AC1Q7EKW, Lopac-P-4015, Lopac0_000898, cid_719408, SCHEMBL1321656, CHEMBL1256364, CTK4C6008, DTXSID20164153, GCZZOZBWAZHCAN-UHFFFAOYSA-N, MolPort-000-402-219, BDBM114545, HMS2886G14, HMS3262D18, ZINC8553055, Tox21_500898, CCG-53204, SBB015047, AKOS001571131, LP00898, MCULE-5028582889, MS-7715, VZ21625, KS-0000298R, NCGC00015811-01, NCGC00015811-02, NCGC00015811-03, NCGC00015811-04, NCGC00094214-01, NCGC00094214-02, NCGC00261583-01, BAS 00344416, CC-04978, ST072638, N-Phenyl-N'-(1,3-thiazol-2-yl)thiourea, Thiourea, 1-phenyl-3-(2-thiazolyl)-2-, DB-042964, KB-160331, LS-160661, EU-0100898, FT-0637155, N-Phenyl-N'-(1,3-thiazol-2-yl)thiourea #, P 4015, A808834, C-13910, SR-01000076066, U-14624, SR-01000076066-1, SR-01000076066-3

ID: 679

InChIKey: GDCXPZPXAWTYJM-LDXVYITESA-N
SMILES: CCN1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)N[C@@H]4CCCC[C@@H]4N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957495
synonyms found at PubChem are:
CGP-74514A hydrochloride, N2-(cis-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine hydrochloride, CGP-74514A, EU-0100291, SCHEMBL2515986, CHEMBL1256911, Tox21_500291, IN2314, CCG-221595, LP00291, NCGC00093743-01, NCGC00260976-01, C 3353, SR-01000075754, J-003582, SR-01000075754-1, N2-(cis-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine hydrochloride; Compound 13

ID: 680

InChIKey: GDLBFKVLRPITMI-UHFFFAOYSA-N
SMILES: CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3019
synonyms found at PubChem are:
diazoxide, 364-98-7, Proglycem, Hyperstat, Eudemine, Hypertonalum, Proglicem, Dizoxide, Mutabase, Diazossido, 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Diazoxido, Diazoxidum, Sch 6783, Diazossido [Italian], Sch-6783, Diazossido [DCIT], SRG 95213, SRG-95213, Diazoxidum [INN-Latin], Diazoxido [INN-Spanish], 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide, Aroglycem, C8H7ClN2O2S, UNII-O5CB12L4FN, Hyperstat (TN), NSC 76130, Diazoxide [USAN:INN:BAN], EINECS 206-668-1, NSC 64198, NSC-64198, 7-chloro-3-methyl-4H-1, Diazoxide (JAN/USP/INN), O5CB12L4FN, MLS000028459, 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido, CHEBI:4495, GDLBFKVLRPITMI-UHFFFAOYSA-N, 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian], NSC64198, NSC76130, 3-methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide, NCGC00015380-09, CAS-364-98-7, SMR000058392, DSSTox_CID_2914, D 9035, DSSTox_RID_76786, DSSTox_GSID_22914, 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine1,1-dioxide, 7-chloro-3-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide, 7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide, 7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide, 7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide, SR-01000075314, 7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide, 2H-1,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide, 7-chloro-3-methyl-2H-1?^{6},2,4-benzothiadiazine 1,1-dioxide, Eudemine injection, Prestwick_163, Diazoxide [USAN:USP:INN:BAN:JAN], Tocris-0964, Opera_ID_608, AC1L1EZN, Prestwick0_000087, Prestwick1_000087, Prestwick2_000087, Prestwick3_000087, Spectrum3_000735, Spectrum4_001248, Lopac-D-9035, CHEMBL181, D07WEP, CBiol_001750, Lopac0_000404, SCHEMBL41254, BSPBio_000014, BSPBio_001307, BSPBio_002290, KBioGR_000027, KBioGR_001776, KBioSS_000027, MLS001076071, MLS001424164, SPECTRUM2300206, SPBio_001953, BPBio1_000016, GTPL2409, CHEMBL1518123, DTXSID7022914, BDBM86248, KBio2_000027, KBio2_002595, KBio2_005163, KBio3_000053, KBio3_000054, KBio3_001510, AOB5782, MolPort-003-666-772, MolPort-003-941-186, Bio1_000036, Bio1_000525, Bio1_001014, Bio2_000027, Bio2_000507, HMS1361B09, HMS1568A16, HMS1791B09, HMS1922L22, HMS1989B09, HMS2051P20, HMS2089L04, HMS2093N12, HMS2095A16, HMS2234B23, HMS3261A10, HMS3267I11, HMS3371L13, HMS3393P20, HMS3402B09, HMS3712A16, Pharmakon1600-02300206, BCP26107, HY-B1140, NSC_3019, ZINC3872277, Tox21_110132, Tox21_500404, ACM364987, BG0437, KC-115, MFCD00078578, NSC-76130, NSC759574, s4630, AKOS015896340, AKOS024458715, Tox21_110132_1, CCG-101062, CCG-204497, CS-4745, DB01119, FCH1327708, KS-1444, LP00404, MCULE-5031397425, NC00312, NSC-759574, IDI1_033777, KS-000010A1, NCGC00015380-01, NCGC00015380-02, NCGC00015380-03, NCGC00015380-04, NCGC00015380-05, NCGC00015380-06, NCGC00015380-07, NCGC00015380-08, NCGC00015380-10, NCGC00015380-11, NCGC00015380-12, NCGC00015380-13, NCGC00022882-03, NCGC00024907-01, NCGC00024907-02, NCGC00024907-03, NCGC00024907-04, NCGC00024907-05, NCGC00024907-06, NCGC00024907-07, NCGC00024907-08, NCGC00261089-01, AN-23421, CAS_364-98-7, CC-26456, CPD000058392, LS-40410, SAM001246872, SC-83321, B6526, D5402, EU-0100404, FT-0603087, Z3125, VU0239714-6, 2270-EP2281815A1, 2270-EP2295550A2, 2270-EP2301933A1, 2270-EP2308838A1, 2270-EP2311827A1, C06949, D00294, EN300-122611, 32273-EP2281815A1, 32273-EP2298415A1, 32273-EP2301933A1, 32273-EP2305640A2, 32273-EP2311827A1, 364D987, A823275, C-13401, I06-2041, SR-01000075314-1, SR-01000075314-3, SR-01000075314-4, SR-01000075314-6, BRD-K73109821-001-05-2, BRD-K73109821-001-10-2, 7-chloro-3-methyl-1,2,4-benzothiadiazine,1,1-dioxide, Diazoxide, European Pharmacopoeia (EP) Reference Standard, 2H-1,2,4-Benzothiadiazine,7-chloro-3-methyl-, 1,1-dioxide, 4H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide, 7-chloro-3-methyl-4H-1|E?,2,4-benzothiadiazine-1,1-dione, Diazoxide, United States Pharmacopeia (USP) Reference Standard, 7-chloranyl-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide, 7-chloro-3-methyl-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide, 7-chloro-3-methyl-4H-1$l;{6},2,4-benzothiadiazine-1,1-dione, 1342899-70-0

ID: 681

InChIKey: GDLMLQJISATCEL-UHFFFAOYSA-M
SMILES: [Li+].CCCCCCCCCCCCCCCCOCC(COCC(F)(F)F)OP(=O)([O-])OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4214
synonyms found at PubChem are:
mj33 lithium salt, MJ33, 199106-13-3, IN1224, 1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol, Li, AC1L1HO4, CTK4E2711, DTXSID30274419, MolPort-003-958-706, lithium 1-(hexadecyloxy)-3-(2,2,2-trifluoroethoxy)propan-2-yl methyl phosphate, RT-013911, MJ33 lithium salt, powder, >=90% (NMR), J-012863, 1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol lithium, lithium [1-hexadecoxy-3-(2,2,2-trifluoroethoxy)propan-2-yl] methyl phosphate, 1007476-63-2, Phosphoric acid lithium methyl 1-[(2,2,2-trifluoroethoxy)methyl]-2-(hexadecyloxy)ethyl ester salt

ID: 682

InChIKey: GDLVLDUGLOXLPW-NBTHXAOBSA-N
SMILES: CC(=O)O[C@@H]1CC2=C(C=C(C=C2O[C@@H]1C3=CC4=C(C(=C(C=C4[C@@H]5C(CC6=C(C=C(C=C6O5)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)C(=O)C(=C3)OC(=O)C)OC(=O)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6710778
synonyms found at PubChem are:
KBio3_003017, Spectrum3_001916, AC1O8K2Y, THEAFLAVIN NONAACETATE, BSPBio_003512, NCGC00178018-01, [(2R,3R)-5,7-diacetyloxy-2-[3,4,6-triacetyloxy-5-oxo-1-[(2R)-3,5,7-triacetyloxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-8-yl]-3,4-dihydro-2H-chromen-3-yl] acetate

ID: 683

InChIKey: GDTYEEIHTCXGOB-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)COCC2=CC(=NO2)C3=NOC(=C3)COCCC4=CC(=NO4)C5=CC=CC=N5

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 10551836
synonyms found at PubChem are:
5-[[2-[3-(2-Pyridinyl)-5-isoxazolyl]ethoxy]methyl]-5'-(benzyloxymethyl)-3,3'-biisoxazole

ID: 684

InChIKey: GDUPBUZZJUIEDX-PNYVIBBQSA-N
SMILES: CC12CCC3C(C1C[C@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)OCC5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5702175
synonyms found at PubChem are:
estriol benzyl ether, NINDS_000552, AC1NWATE, Spectrum_001993, Spectrum2_001442, Spectrum3_000934, Spectrum4_001033, Spectrum5_001027, KBioGR_001585, KBioSS_002562, DivK1c_000552, SPBio_001303, SCHEMBL10026706, HMS501L14, KBio1_000552, KBio2_002553, KBio2_005121, KBio2_007689, KBio3_001968, CCG-39162, IDI1_000552, (16R,17R)-13-methyl-3-phenylmethoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol

ID: 685

InChIKey: GDWDBGSWGNEMGJ-UHFFFAOYSA-N
SMILES: CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 32169
synonyms found at PubChem are:
ARTICAINE HYDROCHLORIDE, 23964-57-0, Articaine HCl, Septanest, Ultracaine, Carticaine hydrochloride, Ultracain, Articaine (hydrochloride), EINECS 245-957-7, HOE 40045, HOE 045, 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl, DSSTox_CID_25444, DSSTox_RID_80885, DSSTox_GSID_45444, Q-200653, Hoe-045, Methyl 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-2-thenoate monohydrochloride, Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride, METHYL 4-METHYL-3-(2-PROPYLAMINOPROPANOYLAMINO)THIOPHENE-2-CARBOXYLATE HYDROCHLORIDE, methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate hydrochloride, 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride, 2-Thiophenecarboxylic acid, 4-methyl-3-(2-(propylamino)propionamido)-, methyl ester, monohydrochloride, Articaine hydrochloride [USAN], methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate;hydrochloride, Articaine hydrochloride [USAN:USP], articain hydrochloride, Aarticaine hydrochloride, NCGC00016784-01, AC1L1N5B, CAS-23964-57-0, MLS002154112, ARONIS24180, SCHEMBL329749, CHEMBL1200819, DTXSID2045444, CTK4F2654, BBC/327, MolPort-006-666-485, HMS1571O05, BCP11709, EBD51009, HY-B0516, ZX-AS004540, Articaine hydrochloride (JAN/USAN), Tox21_110609, BG0647, s3150, SBB080672, AKOS005267121, Tox21_110609_1, AC-1918, API0000403, CCG-221032, CS-2728, H64A581, KS-1404, MCULE-6268951673, NCGC00179248-03, AN-14456, Articaine hydrochloride, >=98% (HPLC), BC683303, S050, SC-20835, SMR001233419, AB0018456, LS-153040, FT-0621704, D02991, K-6482, SR-01000841204, SR-01000841204-2, Articaine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Articaine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Articaine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, methyl 4-methyl-3-(2-(propylamino)propanamido)thiophene-2-carboxylate hydrochloride, methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate, chlo ride, AKOS015896265, I06-2145

ID: 686

InChIKey: GECHUMIMRBOMGK-UHFFFAOYSA-N
SMILES: C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5336
synonyms found at PubChem are:
sulfapyridine, 144-83-2, Sulphapyridine, 2-Sulfapyridine, Sulfidin, Sulfidine, 2-Sulfanilamidopyridine, Streptosilpyridine, Coccoclase, Eubasinum, Piridazol, Pyridazol, Eubasin, Haptocil, Plurazol, 2-Sulfanilylaminopyridine, Relbapiridina, Sulfapiridina, Sulfapyridinum, Pyriamid, Septipulmon, Thioseptal, Adiplon, Dagenan, Trianon, Ronin, 2-Sulfanilamidopyridin, Solfapiridina, N-2-Pyridylsulfanilamide, N1-2-Pyridylsulfanilamide, 4-amino-N-pyridin-2-ylbenzenesulfonamide, 4-amino-N-pyridin-2-yl-benzenesulfonamide, N(sup 1)-2-Pyridylsulfanilamide, 2-(p-Aminobenzenesulphonamido)pyridine, Benzenesulfonamide, 4-amino-N-2-pyridinyl-, 2-Sulfanilyl aminopyridine, Sulphapyridin, 2-(4-Aminobenzenesulfonamido)pyridine, Solfapiridina [DCIT], N(sup1)-Pyridylsulfanilamide, 4-[(2-Pyridylamino)sulfonyl]aniline, 4-(2-Pyridinylsulfonyl)aniline, 4-amino-N-(pyridin-2-yl)benzenesulfonamide, M+B 693, Sulfapyridinum [INN-Latin], Sulfapiridina [INN-Spanish], A-499, 2-Sulfanilamidopyridin [German], N(1)-Pyridylsulfanilamide, M + B 693, UNII-Y5V2N1KE8U, M and B 693, NSC 4753, NSC 41791, Sulfanilamide, N(sup 1)-2-pyridyl-, N(1)-2-Pyridylsulfanilamide, Sulfapyridine (TN), M&B 693, 4-Amino-N,2-pyridinylbenzenesulfonamide, Sulfanilamide, N1-2-pyridyl-, 4-Amino-n-2-pyridinyl-benzenesulfonamide, Sulfapyridine [USAN:INN:BAN], C11H11N3O2S, CHEBI:132842, N'-2-Pyridylsulfanilide, EINECS 205-642-7, Sulfapyridine (USP/INN), Y5V2N1KE8U, AI3-01049, MLS000069725, N1-(Pyridin-2-yl)sulfanilamide, 4-AMINO-N-2-PYRIDINYLBENZENESULFONAMIDE, NSC4753, 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide, GECHUMIMRBOMGK-UHFFFAOYSA-N, ALBB-006215, 4-amino-N-(2-pyridyl)benzenesulfonamide, NCGC00016408-01, CAS-144-83-2, SMR000058213, 4-amino-n-(2-pyridinyl)benzenesulfonamide, DSSTox_CID_6067, DSSTox_RID_78003, DSSTox_GSID_26067, WLN: T6NJ BMSWR DZ, AO-801/41077453, [(4-aminophenyl)sulfonyl]-2-pyridylamine, SR-01000000207, pirodazole, Sulfapyridin, Sulfapyridine [USP:INN:BAN], Prestwick_1015, N1-Pyridylsulfanilamide, Spectrum_000996, Sulfapyridine (Dagenan), Sulfasalazine Impurity J, Prestwick0_000762, Prestwick1_000762, Prestwick2_000762, Prestwick3_000762, Spectrum2_001323, Spectrum3_001773, Spectrum4_000346, Spectrum5_001182, CHEMBL700, D0D4CY, Epitope ID:122235, EC 205-642-7, AC1L1K4N, AC1Q51XL, cid_5336, Sulfapyridine, >=99.0%, Oprea1_344996, SCHEMBL44219, BSPBio_000804, BSPBio_003265, KBioGR_000751, KBioSS_001476, DivK1c_000216, SPECTRUM1500551, SPBio_001445, SPBio_002743, BPBio1_000886, ZINC2105, DTXSID3026067, BDBM39340, CTK3J2133, GECHUMIMRBOMGK-UHFFFAOYSA-, HMS500K18, KBio1_000216, KBio2_001476, KBio2_004044, KBio2_006612, KBio3_002766, MolPort-000-883-306, NINDS_000216, 4-(2-Pyridinylsulfonyl)aniline #, HMS1570I06, HMS1921C03, HMS2092K05, HMS2097I06, HMS2233H20, HMS3372N13, HMS3714I06, Pharmakon1600-01500551, HY-B0212, NSC-4753, NSC41791, Tox21_110426, ANW-43071, BBL007713, CCG-39261, LS-854, NSC-41791, NSC757329, s1617, SBB003154, STK292439, 2-(p-Aminobenzenesulfonamido)pyridine, Sulfanilamide, N1-2-pyridyl-(8CI), AKOS000121424, Tox21_110426_1, CS-2157, DB00891, HS-0063, M&B-693, MCULE-7911106459, NSC-757329, RTR-005667, Sulfanilamide, N1-2-pyridyl- (8CI), VZ28286, IDI1_000216, KS-00000G93, UPCMLD0ENAT5889155:001, NCGC00016408-02, NCGC00016408-03, NCGC00016408-04, NCGC00016408-05, NCGC00016408-06, NCGC00016408-09, NCGC00016408-10, NCGC00022008-03, NCGC00022008-04, Sulfanilamide, N1-2(1H)-pyridylidene-, AC-26818, AN-43961, H460, SC-65296, ZB000484, 4-Amino-N-[2-pyridyl]benzene sulfonamide, 4-Amino-N-2-pyridinyl- benzenesulfonamide, SBI-0051525.P003, 4-azanyl-N-pyridin-2-yl-benzenesulfonamide, AB2000164, DB-042750, TR-005667, AB00052100, BB 0258406, Coccoclase;Eubasin;Eubasinum;Haptocil;Dagenan, FT-0631839, R1664, S0071, ST45026614, Benzenesulfonamide, 4-amino-N-(2-pyridinyl)-, D02434, J10161, AB00052100_14, AB00052100_15, A808279, Sulfapyridine, VETRANAL(TM), analytical standard, I14-1461, SR-01000000207-2, SR-01000000207-3, W-108148, BRD-K41406082-001-05-5, BRD-K41406082-001-09-7, Z271004858, Sulfapyridine, European Pharmacopoeia (EP) Reference Standard, 4-Amino-N-(pyrimidin-2-yl) benzenesulfonamide (Sulfadiazine) (14), Sulfapyridine, United States Pharmacopeia (USP) Reference Standard, Sulfapyridine Melting Point Standard, United States Pharmacopeia (USP) Reference Standard, InChI=1/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14), SFY, Sulfapyridine melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 687

InChIKey: GEFQWZLICWMTKF-CDUCUWFYSA-N
SMILES: C[C@@H]([C@@H](C1=CC(=C(C=C1)O)O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 164739
synonyms found at PubChem are:
levonordefrin, Corbadrine, Neo-Cobefrin, 829-74-3, Corbadrinum, Corbadrina, Nordefrin, alpha-Methylnoradrenaline, Corbadrinum [INN-Latin], Corbadrina [INN-Spanish], L-alpha-Methylnoradrenaline, Levonordefrin [USP], Nordefrin, (-)-, UNII-V008L6478D, Corbadrin, (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol, (-)3,4-Dihydroxynorephedrine, (-)-3,4-Dihydroxynorephedrine, CHEBI:10304, Corbadrine (INN), Corbadrine [INN], Levonordefrin (USP), V008L6478D, CAS-829-74-3, DSSTox_CID_26349, DSSTox_RID_81553, DSSTox_GSID_46349, l-Cobefrin, 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-, (R-(R*,S*))-, Levonordefrin [USAN], SR-05000002090, 3,4-Dihydroxynorephedrin, 4-((1R,2S)-2-amino-1-hydroxypropyl)benzene-1,2-diol, levoepinefrina, L-Nordefrin, alpha-Me-NE, NCGC00163349-01, (-)-cobefrin, 74812-63-8, Neo-cobefrin (TN), BA 2818, Spectrum_001642, Prestwick3_000739, Spectrum2_001055, Spectrum3_000480, Spectrum4_000032, Spectrum5_000912, Lopac-D-5290, CHEMBL677, D0E9VU, AC1L4VD7, (R-(R*,S*))-isomer, BSPBio_000698, BSPBio_002220, GTPL508, KBioGR_000463, KBioSS_002122, (-)-alpha-Methylnoradrenaline, DivK1c_000315, SCHEMBL119171, SPECTRUM1500365, SPBio_001010, BPBio1_000768, DTXSID6046349, HMS500P17, KBio1_000315, KBio2_002122, KBio2_004690, KBio2_007258, KBio3_001440, ZINC34157, (-)-3,4-Dihydroxy Norephedrine, CHEBI:141146, NINDS_000315, erythro-(-)-alpha-(1-Aminoethyl)-3,4-dihydrobenzyl alcohol, HMS1920J07, HMS2091P13, HMS2097C20, HMS3714C20, Pharmakon1600-01500365, Tox21_112051, CCG-40121, NSC757084, AKOS006280500, Tox21_112051_1, DB06707, NSC-757084, IDI1_000315, NCGC00015345-01, NCGC00016542-01, NCGC00016542-02, NCGC00016542-03, NCGC00016542-04, NCGC00016542-06, ST049172, SBI-0051428.P003, LS-177715, AB00513909, FT-0603517, C11768, D02388, AB00052030_04, 829D743, SR-05000002090-1, SR-05000002090-2, I14-45238, 4-((2S,1R)-2-amino-1-hydroxypropyl)benzene-1,2-diol, UNII-R81X549E70 component GEFQWZLICWMTKF-CDUCUWFYSA-N, Levonordefrin, United States Pharmacopeia (USP) Reference Standard, 13725-11-6, 16906-83-5, 18829-78-2, 34535-70-1

ID: 688

InChIKey: GELRVIPPMNMYGS-RVXRQPKJSA-N
SMILES: C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 62878
synonyms found at PubChem are:
Paroxetine hydrochloride, 78246-49-8, Paroxetine Hcl, Paroxat, Aropax 20, (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride, paroxetine (hydrochloride), BRL 29060 hydrochloride, UNII-3I3T11UD2S, 110429-35-1, Paroxetine hydrochloride [USP], BRL 29060A, SDB 7175, 3I3T11UD2S, HSDB 7175, S3005, C19H21ClFNO3, Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, hydrochloride, (3S,4R)-, Paroxetine hydrochloride hemihydrate (MW = 374.83), Paroxetine hydrochloride (USP), CHEMBL1708, (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine hydrochloride, (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride, (-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-methylenedioxy)phenoxy)-methyl)piperidine hydrochloride, (3S-TRANS)-3-[(1,3-BENZODIOXOL-5-YLOXY)METHYL]-4-(4-FLUOROPHENYL)PIPERIDINE HYDROCHLORIDE, Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, hydrochloride, (3S-trans)-, 61869-08-7 (Parent), paroxatene, Paroxetine hydrochloride [USAN], BRL29060A, Paroxetine, HCl, paroxetine (Paxil), paroxetinehydrochloride, AC1L1XYV, C19H20FNO3.HCl, SCHEMBL33348, MLS002222322, PAROXETIN HYDROCHLORIDE, SPECTRUM1504085, CHEBI:7944, KS-00000JOT, DTXSID50228914, GELRVIPPMNMYGS-RVXRQPKJSA-N, MolPort-003-666-523, HMS1922B11, Pharmakon1600-01504085, (-)-trans-paroxetine hydrochloride, HY-B0492, Tox21_500095, ANW-49202, BG0380, CCG-39866, MFCD03658863, NSC758654, AKOS015849162, AKOS015907108, API0003757, CS-2611, H29P351, KS-5097, LP00095, NSC-758654, YF10047, NCGC00093597-01, NCGC00260780-01, AK-49032, AN-15600, BR-49032, SMR001307264, AB0008509, AB1004558, AX8022605, LS-114251, TC-137947, TL8005348, EU-0100095, P1977, ST24025708, D05374, J10285, Paroxetine or other medication - algorithm used, S-2491, 110429-35-1(hemihydrate) 61869-08-7, SR-01000759305, SR-01000759305-6, Z1741971218, (-)-trans-4-(-4-fluorophenyl)-3-(3,4-methylenedioxy-phenoxymethyl)-piperidine hydrochloride, (-)-trans-4-(-4-fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)-piperidine hydrochloride, (-)-trans-4-(4-fluorophenyl)-3-(3,4-methylene dioxyphenoxymethyl)-piperidine hydrochloride, (3S,4R)-3-((BENZO[D][1,3]DIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)PIPERIDINE HCL, (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-piperidine hydrochloride, (-)TRANS-3-[(1,3-BENZODIOXOL-5-YLOXY) METHYL]-4-(4-FLUOROPHENYL) PAROXETINE HYDROCHLORIDE, (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride, (3S,4R)-3-[(1,3-BENZODIOXOL-5-YLOXY)METHYL]-4-(4-FLUOROPHENYL)-PIPERIDINE HYDROCHLORIDE, (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride; Paroxetine Hydrochloride Anhydrous; (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl, (S)-3-(BENZO[1,3]DIOXOL-5-YLOXYMETHYL)-4-(4-FLUORO-PHENYL)-PIPERIDINE HYDROCHLORIDE, Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, hydrochloride,(3S-trans)-

ID: 689

InChIKey: GELVZYOEQVJIRR-UHFFFAOYSA-N
SMILES: C1=CN=C(C=N1)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 73277
synonyms found at PubChem are:
2-Chloropyrazine, 14508-49-7, Chloropyrazine, Pyrazine, chloro-, pyrazine, 2-chloro-, 2-chloro-pyrazine, 2-chloro pyrazine, GELVZYOEQVJIRR-UHFFFAOYSA-N, chioropyrazine, chloropyrazin, chloro-pyrazine, 6-chloropyrazine, 2- chloropyrazine, chloropyrazine, 2-, EINECS 238-517-0, PubChem8546, Pyrazin-2-yl chloride, AC1Q3KUY, AC1Q3PYU, Prestwick0_001087, Prestwick1_001087, Prestwick2_001087, Prestwick3_001087, 2-Chloropyrazine, 97%, ACMC-209cu5, AC1L2JL1, SCHEMBL6771, BSPBio_001134, KSC182Q7R, SPBio_003027, BPBio1_001248, Jsp002642, CHEMBL1741693, DTXSID0065779, CHEBI:95323, CTK0I2878, MolPort-000-141-404, HMS1571I16, HMS2098I16, BCP26699, STR02733, ZINC2008821, ANW-20907, BBL011919, MFCD00006124, STL163428, AKOS000121584, AC-2454, CCG-221087, CS-W018537, LS20940, MCULE-9767491317, PS-9235, RP00611, RTC-068556, TRA0090022, NCGC00016707-01, NCGC00016707-02, AJ-32485, AM803218, AN-13967, BC226186, BP-12074, CJ-07343, CJ-31078, KB-23283, SC-01136, CAS-14508-49-7, DB-006092, ST2409936, TC-068556, TR-031670, AB00514039, FT-0601046, FT-0649350, AZ0001-0478, EN300-21095, B-7269, 20848-EP2301923A1, 20848-EP2305682A1, 20848-EP2308879A1, 20848-EP2314585A1, 58099-EP2287141A1, 58099-EP2301918A1, 58099-EP2305682A1, 58099-EP2308879A1, SR-01000872682, S14-0683, SR-01000872682-1, W-108142, BRD-K84075000-001-03-0, F2173-0204, InChI=1/C4H3ClN2/c5-4-3-6-1-2-7-4/h1-3

ID: 690

InChIKey: GEOCVSMCLVIOEV-BTJKTKAUSA-N
SMILES: CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5358907
synonyms found at PubChem are:
Nomifensine maleate, Nomifensine (maleate), 32795-47-4, NOMIFENSINE MALEATE SALT, NCGC00094199-02, 1,2,3,4-Tetrahydro-2-methyl-4-phenylisoquinolin-8-amine maleate, DSSTox_CID_25790, DSSTox_RID_81131, DSSTox_GSID_45790, 24524-90-1, SR-01000000201, Neurolene, Prestwick_360, EINECS 246-297-2, Merital (TN), NOMIFENSIN MALEATE, AC1NSDD3, Nomifensine Maleic Acid Salt, MLS000069687, SCHEMBL125019, SPECTRUM1503267, CHEMBL1256842, DTXSID1045790, HMS502H11, HY-B1110A, MolPort-003-666-476, HMS1568E18, HMS1922O11, HMS2093C03, HMS2095E18, HMS2232B10, HMS3262P11, HMS3712E18, Pharmakon1600-01503267, Tox21_111258, Tox21_500875, 2594AH, BG0532, CCG-39326, NSC758441, AKOS015962104, Tox21_111258_1, CS-4709, LP00875, NSC-289114, NSC-758441, NCGC00015727-10, NCGC00094199-01, NCGC00094199-03, NCGC00094199-04, NCGC00094199-05, NCGC00261560-01, SMR000058485, KB-216162, EU-0100875, D05200, N 1530, ( inverted exclamation markA)-Nomifensine maleate, I08-0236, J-018882, SR-01000000201-2, SR-01000000201-4, SR-01000000201-6, ( inverted exclamation markA)-Nomifensine Hydrogen Maleate, 8-Amino-1,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate (1:1), (8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline (Z)-2-Butenedioate, (Z)-but-2-enedioic acid; 2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, (Z)-but-2-enedioic acid;2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine (2Z)-2-Butenedioate, 4-cyclohexyl-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-amine (2Z)-2-butenedioate, 8-Isoquinolinamine,2,3,4-tetrahydro-2-methyl-4-phenyl-, (Z)-2-butenedioate (1:1), Hostalival, Psicronizer, Merital AM, Alival (antidepressant), Nomifensine maleate [USAN], CCRIS 1914, (+-)-Nomifensine hydrogen maleate, EINECS 251-223-7, NSC 289114, 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate, 8-Ammonio-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinolinium maleate, 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-, (Z)-2-butenedioate (1:1), AC1O5HEL, MolPort-019-995-863, 24526-64-5 (Parent), AKOS024456897, LS-85808, A821419, ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-8-AMINO-2-METHYL-4-PHENYL-, MALEATE, (Z)-4-hydroxy-4-oxo-2-butenoate; 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium-8-amine, (Z)-4-hydroxy-4-oxobut-2-enoate; 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium-8-amine, 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium-8-amine; (Z)-4-oxidanyl-4-oxidanylidene-but-2-enoate, 98644-14-5

ID: 691

InChIKey: GFFGJBXGBJISGV-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1)C(=NC=N2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 190
synonyms found at PubChem are:
adenine, 73-24-5, 6-Aminopurine, 1H-Purin-6-amine, 9H-Purin-6-amine, Vitamin B4, Adenin, 7H-Purin-6-amine, Adeninimine, Leuco-4, 6-Amino-1H-purine, 6-Amino-3H-purine, 6-Amino-7H-purine, 6-Amino-9H-purine, 1,6-Dihydro-6-iminopurine, 3,6-Dihydro-6-iminopurine, Purine, 6-amino-, USAF CB-18, 1H-Purine, 6-amino, ADE, Adenine [JAN], Pedatisectine B, 9H-Purine, 1,6-dihydro-6-imino-, CCRIS 2556, adenine-ring, AI3-50679, NSC 14666, purine, 6, UNII-JAC85A2161, Leucon (TN), Adenine (8CI), 1H-Purine-6-amine, 9H-Purine-6-amine, 9H-purin-6-ylamine, CHEBI:16708, Adenine (JAN/USP), 1H-Purine, 6-amino-, EINECS 200-796-1, 1H-purin-6(9H)-imine, 1,6-Dihydro-6-Imnopurine, 1H-Purin-6-amine (9CI), CHEMBL226345, purine-6-ylamine, GFFGJBXGBJISGV-UHFFFAOYSA-N, JAC85A2161, ALBB-005925, NCGC00094856-01, Adenine-8-14C, DSSTox_CID_2557, 2'-DEOXY-ADENOSINE-3'-5'-DIPHOSPHATE, DSSTox_RID_76627, DSSTox_GSID_22557, 134434-49-4, 134454-76-5, 66224-65-5, 66224-66-6, 71660-29-2, 71660-30-5, CAS-73-24-5, 134434-48-3, 134461-75-9, 66224-67-7, 66224-69-9, AD2, ANE, Vitamin B 4, 4, Vitamin B, B 4, Vitamin, Adenine [USP:JAN], SR-05000001754, 6-Aminopurine (Adenine), 3H-PURIN-6-AMINE, 3h-adenine, 6-amino purine, 6-amino-Purine, 1jys, 1nli, 1wei, 2pqj, 3kpv, Vitamin-B4, [3H]adenine, Adenine, 1, Adenine,(S), 6-Aminopurine phospha, 7H-purin-6-ylamine, PubChem9587, 9H-Purin-6-yl-amin, PubChem14133, Spectrum_001106, 2p8n, 9H-Purin-6-yl-amine, SpecPlus_000535, Adenine, >=99%, 9H-Purin-6-amine #, Spectrum2_000583, Spectrum3_000616, Spectrum4_001891, Spectrum5_000542, 3H-purin-6(9H)-imine, bmse000060, bmse000861, bmse000995, D08IBS, Epitope ID:140097, 3H-Purin-6(7H)-imine, Adenine, 99% 50g, AC1L18OI, AC1Q52XT, SCHEMBL8110, 6-Aminopurine; Vitamin B4, ACMC-1BC21, Oprea1_057274, US9138393, Adenine, US9144538, Adenine, BSPBio_002152, KBioGR_002447, KBioGR_002562, KBioSS_001586, KBioSS_002571, ZINC882, KSC375M3B, MLS001066342, 3H-Purin-6-amine (9CI), 7H-Purin-6-amine (9CI), 9H-Purin-6-amine (9CI), DivK1c_006631, SPECTRUM1500807, SPBio_000426, AC1Q52Y5, GTPL4788, 9H-Purine,6-dihydro-6-imino-, DTXSID6022557, BDBM33218, CTK1I0610, CTK1I0611, CTK2H5630, CTK2H5631, CTK8C4706, CTK8J9100, CTK8J9101, CTK8J9102, KBio1_001575, KBio2_001586, KBio2_002562, KBio2_004154, KBio2_005130, KBio2_006722, KBio2_007698, KBio3_001652, KBio3_003040, cMAP_000085, MolPort-001-785-186, MolPort-001-785-762, MolPort-004-759-679, BCPP000433, BDBM181146, HMS1921I14, HMS2092K20, HMS2269I04, Pharmakon1600-01500807, BCP02865, HY-B0152, NSC14666, 6H-Purin-6-imine, 1,9-dihydro-, Tox21_111348, Tox21_302108, ANW-36312, ANW-72859, BBL007925, CA0118, CCG-38506, HTS027705, MFCD00041790, NSC-14666, NSC757793, s1981, SBB017528, STK387542, WLN: T56 BM DN FN HNJ IZ, AKOS000118903, AKOS005171607, AKOS016000265, AKOS027322497, Tox21_111348_1, AC-2028, AM83908, BCP9000233, CS-1984, DB00173, MCULE-6556342774, NSC-757793, RP17323, RTR-023809, SDCCGMLS-0066584.P001, NCGC00094856-02, NCGC00094856-03, NCGC00094856-05, NCGC00255120-01, 66224-68-8, AJ-07930, AN-14387, AS-11841, BL008313, CJ-00019, KB-46998, LS-15058, NCI60_000998, SC-09021, SMR000471871, TL806440, ZB000195, SBI-0052324.P002, 6H-Purin-6-imine, 1,7-dihydro- (9CI), 6H-Purin-6-imine, 3,7-dihydro- (9CI), 6H-Purin-6-imine, 3,9-dihydro- (9CI), AB1004094, AB1009319, Adenine, Vetec(TM) reagent grade, >=99%, DB-013503, KB-199046, KB-249881, ST2408921, TC-161604, TL8005091, TR-023809, A0149, FT-0082877, FT-0620943, FT-0656198, ST50298870, T6972, 4175-EP2270010A1, 4175-EP2270015A1, 4175-EP2270505A1, 4175-EP2272517A1, 4175-EP2275404A1, 4175-EP2292088A1, 4175-EP2292593A2, 4175-EP2295441A2, 4175-EP2295503A1, 4175-EP2295550A2, 4175-EP2298783A1, 4175-EP2301536A1, 4175-EP2301538A1, 4175-EP2303884A1, 4175-EP2305250A1, 4175-EP2305808A1, 4175-EP2311455A1, 4175-EP2316452A1, 73A245, Adenine, suitable for cell culture, BioReagent, C-4677, C00147, D00034, AB00052833-18, AB00052833-19, AB00052833_20, AB00052833_22, AB00052833_23, AB00052833_24, 6-Aminopurine hemisulfate salt; Adenine sulfate salt, 6H-Purin-6-imine, 1,7-dihydro-, (Z)- (9CI), 6H-Purin-6-imine, 1,9-dihydro-, (E)- (9CI), 6H-Purin-6-imine, 3,7-dihydro-, (Z)- (9CI), 6H-Purin-6-imine, 3,9-dihydro-, (Z)- (9CI), I06-0527, I07-0071, I14-7794, Q-200595, SR-05000001754-1, SR-05000001754-2, W-106856, I14-23800, Adenine, BioReagent, plant cell culture tested, >=99%, Adenine, European Pharmacopoeia (EP) Reference Standard, F0001-1848, Z1250132272, 6379C0E0-C1BB-4087-96C5-1DE281B8EA4C, Adenine, United States Pharmacopeia (USP) Reference Standard, Adenine, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10, 1000264-10-7, 22051-90-7, 42911-33-1, 42911-34-2, 520-75-2

ID: 692

InChIKey: GFFJYISJZJIKAF-UHFFFAOYSA-N
SMILES: C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957618
synonyms found at PubChem are:
L-745,870 hydrochloride, CHEMBL555670, NCGC00094126-01, 3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine hydrochloride, SR-01000075388, EU-0100791, UNII-X2UD7T27FU, X2UD7T27FU, MLS002153286, CTK8G0466, Tox21_500791, CCG-222095, LP00791, NCGC00261476-01, SMR001230711, L-131, SR-01000075388-1

ID: 693

InChIKey: GFGSZUNNBQXGMK-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1[N+](=O)[O-])Cl)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2075
synonyms found at PubChem are:
2-Chloro-4-nitrobenzamide, aklomide, 3011-89-0, Aklomix, Clomide, Alkomide, Benzamide, 2-chloro-4-nitro-, component of Aklomix, component of Novastat-W, UNII-B0E341RA20, 2-CHLORO-4-NITRO BENZAMIDE, NSC 191832, GFGSZUNNBQXGMK-UHFFFAOYSA-N, B0E341RA20, NCGC00094557-01, DSSTox_CID_21405, DSSTox_RID_79716, DSSTox_GSID_41405, Aklomida, Aklomidum, CAS-3011-89-0, Caswell No. 198A, Aklomidum [INN-Latin], SR-01000318823, 2-Chlor-4-nitrobenzamid, Aklomida [INN-Spanish], Aklomide [USAN:INN:BAN], Novastat, Novastat-W, EINECS 221-143-7, ACMC-20anzk, EPA Pesticide Chemical Code 298100, Aklomide (USAN/INN), AC1Q5DZD, Spectrum2_001511, Spectrum3_001544, Spectrum4_000923, Spectrum5_001605, M & B 5921, AC1L1CV0, BSPBio_002988, KBioGR_001446, ZINC887, Benzamide,2-chloro-4-nitro-, DivK1c_000648, SCHEMBL328368, SPECTRUM1503014, SPBio_001581, CHEMBL1450565, DTXSID3041405, component of Aklomix (Salt/Mix), CTK4G4469, HMS502A10, KBio1_000648, KBio3_002488, CHEBI:109542, component of Novastat (Salt/Mix), MolPort-000-147-065, NINDS_000648, HMS1922A03, HMS2092H10, Pharmakon1600-01503014, ACT07769, HY-B1094, component of Novastat-W (Salt/Mix), Tox21_111296, Tox21_301142, CCG-39930, NSC191832, NSC758209, SBB092660, STK061509, AKOS003260176, Tox21_111296_1, CS-4682, MCULE-5665968434, NE10777, NSC-191832, NSC-758209, PS-4712, VZ24266, IDI1_000648, NCGC00094557-02, NCGC00094557-03, NCGC00094557-04, NCGC00094557-05, NCGC00094557-06, NCGC00255040-01, KB-68460, ZB000198, SBI-0051750.P002, DB-020837, TR-032820, FT-0611788, ST50407527, V0331, Aklomide, VETRANAL(TM), analytical standard, D02785, AB00052299_02, J-017786, SR-01000318823-1, SR-01000318823-2, BRD-K26807903-001-03-5, I01-13941

ID: 694

InChIKey: GFIGWAJEIMHJJB-LINSIKMZSA-N
SMILES: CO[C@H]1CC=C2CCN3[C@]2(C1)C4=C(CC3)COC(=O)C4.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957537
synonyms found at PubChem are:
Dihydro-beta-erythroidine hydrobromide, 29734-68-7, UNII-NS1U03GC05, MLS002172468, NS1U03GC05, CHEMBL1319741, (2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-one hydrobromide, DH?E, EU-0100468, SCHEMBL1320306, MolPort-003-940-972, Dihydro-?-erythroidine hydrobromide, Tox21_500468, AKOS024457064, LP00468, NCGC00093880-01, NCGC00261153-01, SMR001254098, 3|A-1,6-Didehydro-14,17-dihydro-3-methoxy-16(15H)-oxaerythrinan-15-one hydrobromide, 3beta-1,6-Didehydro-14,17-dihydro-3-methoxy-16(15H)-oxaerythrinan-15-one hydrobromide

ID: 695

InChIKey: GFNANZIMVAIWHM-OBYCQNJPSA-N
SMILES: C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 31307
synonyms found at PubChem are:
triamcinolone, 124-94-7, Fluoxyprednisolone, Aristocort, Rodinolone, Triamcinolon, Kenacort, Volon, Adcortyl, Delphicort, Ledercort, Triamcet, Tricortale, Celeste, Triam-Tablinen, Cinolone-T, SK-Triamcinolone, Triamcinlon, Triamcinolona, Triamcinolonum, Mycolog, Omcilon, Fluoxiprednisolone, Kenacort-AG, Triamcinolonum [INN], Aristocort Tablets, Tiamcinolonum, Triamcinalone, Tiamcinolonum [INN-Latin], Triamcinolona [INN-Spanish], Cinolone, 9alpha-Fluoro-16alpha-hydroxyprednisolone, CL 19823, Tristoject, Fougera, Omicilon, Trilone, UNII-1ZK20VI6TY, Aristocort (TN), Kenacort (TN), C21H27FO6, HSDB 3194, 9-alpha-Fluoro-16-alpha-hydroxyprednisolone, 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, EINECS 204-718-7, Triamcinolone [USAN:INN:BAN:JAN], NSC 13397, (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, BRN 2341955, 1ZK20VI6TY, Prednisolone, 9-fluoro-16alpha-hydroxy-, MLS000028542, MLS001066543, CHEBI:9667, 9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone, NSC13397, 9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione, SMR000058333, Prednisolone, 9-fluoro-16.alpha.-hydroxy-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-, DSSTox_CID_20742, DSSTox_RID_79584, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11-beta,16-alpha)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha), Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)-, DSSTox_GSID_40742, (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, 11.beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione, 11beta,16alpha,17alpha,21-Tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione, 9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione, 9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 9alpha-Fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione, TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7)), Triamcinolone (Aristocort), Triaderm, 9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione, Triamcinolone Base, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11.beta.,16.alpha.)-, Tricortone (TN), Tristoject (TN), Triesence (TN), NCGC00094799-01, CAS-124-94-7, Triamcinolone [USP:INN:BAN:JAN], Prestwick_438, Fougera (TN), Triderm (TN), Trilone (TN), Tri-Nasal (TN), Triamcinolone, topical, Volon A (TN), AC1L1LDH, AC1Q5HJC, Prestwick0_000120, Prestwick1_000120, Prestwick2_000120, Prestwick3_000120, D03BLF, SCHEMBL4447, CHEMBL1451, Lopac0_001179, BSPBio_000140, 4-08-00-03629 (Beilstein Handbook Reference), cid_31307, MLS002695935, SPBio_002079, BPBio1_000154, GTPL2870, DTXSID1040742, Pregna-1,4-diene-3,20-dio, BDBM41132, Triamcinolone (JP15/USP/INN), Triamcinolone (JP17/USP/INN), (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione, 9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione, GFNANZIMVAIWHM-OBYCQNJPSA-N, MolPort-002-528-981, HMS1568G22, HMS2090D12, HMS2095G22, HMS2231E20, HMS3263L19, HMS3712G22, BCP11941, HY-B0328, ZINC3882036, droxypregna-1,4-diene-3,20-dione, Tox21_111332, Tox21_300178, Tox21_501179, LS-698, MFCD00010477, NSC-13397, s1933, AKOS015895436, Tox21_111332_1, AC-2072, CCG-205253, CS-2370, DB00620, LP01179, BRN-2341955, SMP1_000300, NCGC00021580-03, NCGC00021580-04, NCGC00021580-05, NCGC00021580-06, NCGC00021580-07, NCGC00021580-08, NCGC00178404-03, NCGC00254049-01, NCGC00261864-01, 51855-44-8, AN-14322, AS-13657, BC214769, NCI60_000750, SC-46306, AB1010916, EU-0101179, D00385, J10062, 124T947, SR-01000000079, SR-01000000079-3, 9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy, BRD-K77554836-001-03-3, BRD-K77554836-001-14-0, Triamcinolone, British Pharmacopoeia (BP) Reference Standard, Triamcinolone, European Pharmacopoeia (EP) Reference Standard, WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ, Triamcinolone, United States Pharmacopeia (USP) Reference Standard, 9.alpha.-Fluoro-11.beta.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione, 9.alpha.-Fluoro-11.beta.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, Pregna-1,20-dione, 9-fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, 11.beta.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione, 9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d, 9.alpha.-Fluoro-11.beta.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione, 9|A-Fluoro-11|A,16|A,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione; Fluoxyprednisolone, Pregna-1,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11.beta.,16.alpha.)-, Pregna-1,4-diene-3, 20-dione, 9-fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI), Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-(8CI), (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-5-one, (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one, 83474-03-7, 9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)-, tetrahydro deriv.

ID: 696

InChIKey: GFNNBHLJANVSQV-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2051
synonyms found at PubChem are:
AG-1478, Tyrphostin AG 1478, 153436-53-4, N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine, 175178-82-2, Tyrphostin AG-1478, AG 1478, 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline, AG1478, TYRPHOSTIN, AG-1478 hydrochloride, CHEMBL7917, CHEBI:75404, IN1030, N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine, 4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-, AG-1478 (Tyrphostin AG-1478), N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine, BRD6408, BRD-6408, SR-01000076156, NSC693255, tyrphostin AG1478, PubChem22408, Tocris-1276, AC1Q3OYU, BiomolKI_000018, Maybridge1_004001, Lopac-T-4182, BiomolKI2_000028, D0ZH1U, AC1L1CT3, DSSTox_CID_30044, CBiol_002058, DSSTox_GSID_51447, Lopac0_001127, Oprea1_653581, SCHEMBL93838, BSPBio_001390, KBioGR_000110, KBioSS_000110, MLS006012026, n-(3-chlorphenyl)-6,7-dimethoxy-4-chinazolinamin, PD153035 Analog 31, BDBM3532, GTPL4862, DTXSID0051447, BCBcMAP01_000035, CTK0H4249, HMS552N19, KBio2_000110, KBio2_002678, KBio2_005246, KBio3_000219, KBio3_000220, KS-00001PSC, AOB2928, GFNNBHLJANVSQV-UHFFFAOYSA-N, MolPort-001-734-428, Bio1_000344, Bio1_000833, Bio1_001322, Bio2_000110, Bio2_000590, HMS1361F12, HMS1791F12, HMS1989F12, HMS3229O03, HMS3263B15, HMS3656B19, ZINC116937, BCP07988, BCP15152, EX-A1236, KS-00000I0W, Tyrphostin AG 1478, >=98%, Tox21_303781, Tox21_501127, CCG-52663, IN2334, s2728, AKOS002350880, AG-1478 - Tyrphostin AG-1478, AG-1478/AG1478, CS-1606, KIN0001450, LP01127, MCULE-8403703571, NSC-693255, RL01961, VZ27727, IDI1_033860, KS-0000185L, NCGC00016017-01, NCGC00016017-02, NCGC00016017-03, NCGC00016017-04, NCGC00016017-05, NCGC00016017-06, NCGC00016017-07, NCGC00016017-08, NCGC00016017-09, NCGC00016017-20, NCGC00025093-01, NCGC00025093-02, NCGC00025093-03, NCGC00025093-04, NCGC00025093-05, NCGC00261812-01, NCGC00357072-01, 4CA-0124, AJ-11523, AK-63142, AN-16876, AN-30850, GK 03499, HY-13524, NCI60_033425, SMR001456495, ZB003901, DB-026463, KB-333907, RT-011360, Tyrphostin AG-1478;153436-53-4, CAS-175178-82-2, EU-0101127, FT-0643504, FT-0643682, 6,7-dimethoxy-4-(3'-chloroanilino)quinazoline, A15294, A24890, S-7703, T 4182, 11N-812, CU-00000000399-1, J-011074, J-519544, SR-01000076156-1, SR-01000076156-4, SR-01000076156-7, BRD-K68336408-001-02-6, BRD-K68336408-003-02-2, I14-40939, COC1=C(OC)C=C2C(NC3=CC(Cl)=CC=C3)=NC=NC2=C1, 0TO

ID: 697

InChIKey: GGCJGNBVVMDYKM-UHFFFAOYSA-N
SMILES: C1C2=NC(=NC=C2C3=C(C(=O)N1)NC(=C3Br)Br)N

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"DY Thomas" "RG Linington" "DE Williams" "CA Gray" "HM Sampson" "R Robert" "SM Anjos" "RM Centko" "L Yan" "D Zhang" "RJ Andersen" "JW Hanrahan" "J Liao" "RA Keyzers" "KA Teske" "GW Carlile"

"DY Thomas" "Q Yang" "R Solari" "R Andersen" "JW Hanrahan" "E Matthes" "R Robert" "CM Edge" "V Birault" "GW Carlile" "R Hatley"

CID is 11440210
synonyms found at PubChem are:
Latonduine A, SCHEMBL13042347

ID: 698

InChIKey: GGCLNOIGPMGLDB-GYKMGIIDSA-N
SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CCC(=O)C4)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 9908107
synonyms found at PubChem are:
5-Cholesten-3-one, CHOLEST-5-EN-3-ONE, 601-54-7, Oxidized cholesterol, Cholesterone, 3-Keto Cholesterol, 3-ketocholesterol, Cholestenone (delta 5), NSC 118979, UNII-58D45D7T5H, CHEBI:63906, GGCLNOIGPMGLDB-GYKMGIIDSA-N, 58D45D7T5H, delta(sup 5)-Cholestenone, EINECS 210-004-6, .delta.(sup5)-Cholestenone, 5-Cholestenone, 3-Oxocholest-5-ene, 3-Keto-5-cholestene, Delta(5)-cholestenone, SCHEMBL288930, CHEMBL307301, CTK2F4715, DTXSID40208841, ZINC6569094, ANW-69614, LMST01010248, AKOS016006104, AJ-56380, BP-13156, SC-48055, KB-197502, TC-158359, X2096

ID: 699

InChIKey: GGIPOZCJJKKBBV-UHFFFAOYSA-N
SMILES: C1C2C(C3=C(O1)C(=C(C=C3)O)O)OC4=CC5=C(C=C24)OCO5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 24013844
synonyms found at PubChem are:
4-Hydroxymaackiain, 3,4-Dihydroxy-8,9-methylenedioxypterocarpan, CHEMBL490702, ACon1_001836, 9-HYDROXYDEMETHYLPTEROCARPIN, LMPK12070080, BRD-A49758889-001-01-7

ID: 700

InChIKey: GGMCFLXPZMBJMV-NPVWYNPDSA-N
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)OC)O)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5489090
synonyms found at PubChem are:
Centaurein, UNII-Y985P9U3S7, 35595-03-0, Y985P9U3S7, AC1NUR2B, CHEMBL484037, DTXSID20189063, MCULE-2537205840, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-7-[(2S, 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, NCGC00385512-01!5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

ID: 701

InChIKey: GGUSQTSTQSHJAH-UHFFFAOYSA-N
SMILES: C1CN(CCC1CC2=CC=C(C=C2)F)CC(C3=CC=C(C=C3)Cl)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 60703
synonyms found at PubChem are:
Eliprodil, 119431-25-3, Eliprodil [INN], C20H23ClFNO, SL 82-0715, CHEMBL28564, SL 820715, alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NCGC00092329-02, 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-(4-fluorophenyl)-, (+-)-, DSSTox_CID_25744, DSSTox_RID_81089, DSSTox_GSID_45744, 1-(4-Chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethanol, (+-)-alpha-(p-Chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol, 1-(4-chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanol, 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-((4-fluorophenyl)methyl)-, (+-)-, CAS-119431-25-3, UNII-YW62A6TW29, SL-820715, AC1Q3NGJ, SL 82.0715, D0S8CI, AC1L1TR8, MLS006010706, SCHEMBL154047, YW62A6TW29, DTXSID1045744, CHEBI:91784, CTK8E9229, EX-A878, MolPort-003-941-250, HMS3261M16, HMS3268B06, (4-chlorophenyl)-4-((4-fluorophenyl)methyl)-1-piperidineethanol, BCP23813, KS-00001D2U, Tox21_111194, Tox21_500467, 3607AH, BDBM50079387, BN0206, MFCD00866651, PDSP1_000365, PDSP2_000363, AKOS015850327, Eliprodil, >=98% (HPLC), powder, Tox21_111194_1, CCG-221771, DB12869, LP00467, RTR-003265, TRA0018540, NCGC00092329-01, NCGC00092329-03, NCGC00092329-04, NCGC00092329-06, NCGC00261152-01, HY-12881, SMR001456245, LS-172417, TR-003265, EU-0100467, FT-0716701, C-33107, SR-01000597358, J-004126, SR-01000597358-1, BRD-A61392169-001-01-9, 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol

ID: 702

InChIKey: GGXKWVWZWMLJEH-UHFFFAOYSA-N
SMILES: CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3324
synonyms found at PubChem are:
famciclovir, 104227-87-4, Famvir, Famciclovirum, 2-(2-(2-Amino-9H-purin-9-yl)ethyl)propane-1,3-diyl diacetate, Famciclovirum [INN-Latin], BRL-42810, BRL 42810, Anti-Farnesyl Rabbit pAb, Famciclovir (Famvir), Oravir, UNII-QIC03ANI02, Famvir (TN), Famciclovir [USAN:BAN:INN], FAMCYCLOVIR, 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate, FCV, 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine, IN1338, QIC03ANI02, Famciclovir (JAN/USAN/INN), CHEBI:4974, [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-1,3-propanediol diacetate, GGXKWVWZWMLJEH-UHFFFAOYSA-N, C14H19N5O4, 2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate (ester), 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine, NCGC00095133-01, Acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate, DSSTox_CID_3038, 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester), DSSTox_RID_76845, DSSTox_GSID_23038, [2-(acetoxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate, Diacetyl 6-deoxy-9-(4-hydroxy-3-hydroxymethyl-but-1-yl)guanine, 2-(2-(2-AMINO-9H-PURIN-9-YL)ETHYL)-1,3-PROPANEDIOL DIACETATE ESTER, 2-(acetoxymethyl)-4-(2-amino-4,5-dihydro-9H-purin-9-yl)butyl acetate, 2-[2-(2-Amino-9H-purin-9-yl)ethyl]trimethylene diacetate;2-[2-(2-Amino-9H-purin-9-yl)ethyl]trimethylene diacetate, SMR000466375, CAS-104227-87-4, SR-01000759358, famcivir, famtrex, (2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl) acetate, [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl] acetate, Famciclovir [USAN:INN:BAN], 1,3-propanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-, diacetate (ester), 2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol diacetate (ester), HSDB 8121, Famciclovir,(S), 1,3-diyl diacetate, Spectrum_000466, AC1L1FOB, Spectrum2_001101, Spectrum3_001675, Spectrum4_000611, Spectrum5_001548, CHEMBL880, D0VT8P, SCHEMBL2949, BSPBio_003489, KBioGR_001162, KBioSS_000946, MLS000759505, MLS001424115, MLS006011896, SPECTRUM1505201, SPBio_001202, DTXSID0023038, CTK8B7737, Famciclovir, >=98% (HPLC), KBio2_000946, KBio2_003514, KBio2_006082, KBio3_002709, KS-00000XOD, MolPort-003-666-602, HMS1922L09, HMS2051G22, HMS2090G10, HMS2093K12, HMS2232H09, HMS3262O08, HMS3370D14, HMS3393G22, HMS3656A04, HMS3715F03, Pharmakon1600-01505201, ALBB-027262, BCP21312, ZINC1530635, Tox21_111442, Tox21_500793, AK-120, ANW-58321, CCG-39277, CF0039, MFCD00866964, NSC758921, s2467, STK623204, AKOS005556609, Tox21_111442_1, AB07547, AC-8066, AN-8356, CS-1357, DB00426, KS-5020, MCULE-6850246103, NC00156, NSC-758921, NCGC00095133-02, NCGC00095133-03, NCGC00095133-04, NCGC00095133-06, NCGC00261478-01, AJ-26674, BC201648, CJ-23991, CPD000466375, HY-17426, I789, SAM001246732, SC-43883, SBI-0206743.P001, AB0013893, AB2000579, KB-220353, LS-120147, RT-012693, F0842, FT-0602549, A19583, D00317, K-0411, 2-(2-(2-amino-9H-purin-9-yl)ethyl)propane-, AB00639952-06, AB00639952-08, AB00639952_09, AB00639952_10, 227F874, I03-0096, J-001134, SR-01000759358-4, SR-01000759358-5, 9-(4-acetoxy-3-acetoxymethylbut-1-yl)-2-aminopurine, BRD-K45033733-001-02-3, BRD-K45033733-001-05-6, 9-[4-acetoxy-3-(acetoxymethyl)butyl]-2-amino-9h purine, Famciclovir, United States Pharmacopeia (USP) Reference Standard, 1,3-Propanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-, 1,3-diacetate, Famciclovir, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 703

InChIKey: GHASVSINZRGABV-UHFFFAOYSA-N
SMILES: C1=C(C(=O)NC(=O)N1)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3385
synonyms found at PubChem are:
5-Fluorouracil, fluorouracil, 51-21-8, 5-FU, Fluoroplex, Adrucil, Efudex, Carac, Fluracil, Fluoroblastin, 5-fluoropyrimidine-2,4(1H,3H)-dione, Kecimeton, Carzonal, Timazin, Arumel, Efudix, Fluril, Fluracilum, Queroplex, Ulup, 5-Fluoracil, Phthoruracil, Fluro Uracil, Fluorouracilum, Ftoruracil, Efurix, Fluri, 5 Fluorouracil, Effluderm (free base), 5-fluoro-1H-pyrimidine-2,4-dione, 5-Fluoro-2,4(1H,3H)-pyrimidinedione, Fluorouracilo, Fluroblastin, Phtoruracil, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-, 2,4-Dihydroxy-5-fluoropyrimidine, Fluoro-uracile, Fluoro-uracilo, 5-Fluoropyrimidine-2,4-dione, Uracil, 5-fluoro-, 5-Fluoruracil, 5-Faracil, Cinco FU, Fluorouracile, Fluoruracil, Effluderm, Ro 2-9757, 5-Fluor-2,4-pyrimidindiol, Fluorouracile [DCIT], 5-Fluoracil [German], 5-fluoro uracil, 5-Fluoracyl, 5-Ftouracyl, 5-Fluoruracil [German], Fluorouracil, 5-, Fluorouracilum [INN-Latin], Fluorouracilo [INN-Spanish], 5-Fluoropyrimidin-2,4-diol, 5-fluoropyrimidine-2,4-diol, NSC 19893, 2,4-Dioxo-5-fluoropyrimidine, 5-Fluoro-2,4-pyrimidinedione, 5-Fluor-2,4-dihydroxypyrimidin, U-8953, 5-fluoro-uracil, Fluoroplex (TN), FU, 5-Fluor-2,4-pyrimidindiol [Czech], NSC-19893, Adrucil (TN), C4H3FN2O2, UNII-U3P01618RT, CCRIS 2582, Carac (TN), 5-Fluor-2,4-dihydroxypyrimidin [Czech], HSDB 3228, Fluorouracil (Adrucil), 5-Fluor-2,4(1H,3H)-pyrimidindion [Czech], Fluorouracil [USAN:INN:BAN:JAN], EINECS 200-085-6, IN1335, 5-Fluor-2,4(1H,3H)-pyrimidindion, CHEMBL185, Ro-2-9757, 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione, 5-fluoro-2,4-Pyrimidinediol, inhibits thymilidate synthetase, 2,4-Dioxo-5-fluoropryimidine, AI3-25297, MLS000069498, 5FU, 5-FU (TN), CHEBI:46345, GHASVSINZRGABV-UHFFFAOYSA-N, U 8953, U3P01618RT, 1-fluoro-1h-pyrimidine-2,4-dione, NSC19893, 191047-65-1, URF, NCGC00015442-02, Fluracedyl, SMR000038082, DSSTox_CID_634, F0151, F 6627, DSSTox_RID_75705, DSSTox_GSID_20634, Flurodex, Neofluor, Onkofluor, Ribofluor, Haemato fu, Haemato-fu, Fluorouracil GRY, Fluorouracil-GRY, Fluorouracil Cream, CAS-51-21-8, 191047-64-0, 191115-88-5, 5 FU Lederle, 5-FU Lederle, Fluorouracile Dakota, Fluoro Uracile ICN, Fluoro-Uracile ICN, 5 FU medac, 5-fluoro-1,3-dihydropyrimidine-2,4-dione, 5-FU medac, 5 HU Hexal, 5-HU Hexal, Dakota, Fluorouracile, 5 Fluorouracil biosyn, 5-Fluorouracil-biosyn, Fluorouracil Mononitrate, Fluorouracilo Ferrer Far, SR-01000075881, Fluorouracil Potassium Salt, Fluorouracil Monosodium Salt, tetratogen, Fluouracil, Tolak, Fluorouracil Monopotassium Salt, 5-fluorourasil, Fluoro Uracil, 5-florouracil, 5-fluorouacil, 5-Fluracil, 1upf, 5F-uracil, Adrucil (ICN), Efudex (TN), Cantide + 5-FU, Adrucil (Fluorouracil), Fluorouracil - Adrucil, Fluorouracil [USAN:USP:INN:BAN:JAN], Fluorouracil Teva Brand, Spectrum_000841, ACMC-1ATRK, Opera_ID_134, 5-Fluorouracil, 99%, TS antisense + 5-FU, AC1L1FTE, Spectrum2_000076, Spectrum3_000434, Spectrum4_000557, Spectrum5_000718, WLN: T6MVMVJ EF, Lopac-F-6627, Gry Brand of Fluorouracil, CSP Brand of Fluorouracil, ICN Brand of Fluorouracil, D05LEO, D08EPN, D0A7VK, D0K7CG, Dermik Brandof Fluorouracil, Teva Brand of Fluorouracil, UPCMLD-DP130, EC 200-085-6, medac Brand of Fluorouracil, AC1Q4N2X, Hexal Brand of Fluorouracil, Roche Brand of Fluorouracil, SCHEMBL3646, 5-fluorpyrimidin-2,4-diol, biosyn Brand of Fluorouracil, Dakota Brand of Fluorouracil, Ferrer Brand of Fluorouracil, Lopac0_000536, BSPBio_002048, KBioGR_001253, KBioSS_001321, Haemato Brand of Fluorouracil, KSC270K6T, MLS002415705, Neocorp Brand of Fluorouracil, Riemser Brand of Fluorouracil, 5-Fluorouracil, 99% 5g, DivK1c_000054, SPECTRUM1500305, Allergan Brand of Fluorouracil, SPBio_000291, 5-fluoro-2,4-dioxo-pyrimidin, 5-fluoro-pyrimidine-2,4-diol, Dermatech Brand of Fluorouracil, GTPL4789, Onkoworks Brand of Fluorouracil, DTXSID2020634, UPCMLD-DP130:001, CTK1H0569, CTK8H4220, Fluorouracil (JP15/USP/INN), Fluorouracil (JP17/USP/INN), HMS500C16, KBio1_000054, KBio2_001321, KBio2_003889, KBio2_006457, KBio3_001268, ribosepharm Brand of Fluorouracil, 5-Fluoro-2,3H)-pyrimidinedione, 2,4-Pyrimidinedione, 5-fluoro-, MolPort-000-156-102, MolPort-003-990-447, NINDS_000054, BCPP000428, HMS1920O18, HMS2090I04, HMS2091F19, HMS3259O03, HMS3261L13, HMS3654K22, HMS3715H03, Pharmakon1600-01500305, 5-Fluorouracil, analytical standard, BCP02083, KS-00000DY3, 2,3H)-Pyrimidinedione, 5-fluoro-, Tox21_110150, Tox21_202335, Tox21_300112, Tox21_500536, ANW-31214, BBL009635, BDBM50340677, CCG-39879, CF0033, DL-399, LS-153, MFCD00006018, NSC757036, Ro-29757, RW2456, s1209, SBB085751, STK297802, STL367375, ZINC38212689, AKOS000119162, AKOS003237897, AKOS008044307, AKOS022965835, Tox21_110150_1, AN-7240, BCP9000239, CS-0993, DB00544, KS-5129, LP00536, LS40596, MCULE-6338086431, NC00454, NSC-757036, RP19888, IDI1_000054, 2,4-Pyrimidinediol, 5-fluoro- (9CI), NCGC00015442-01, NCGC00015442-03, NCGC00015442-04, NCGC00015442-05, NCGC00015442-06, NCGC00015442-07, NCGC00015442-08, NCGC00015442-09, NCGC00015442-10, NCGC00015442-11, NCGC00015442-12, NCGC00015442-15, NCGC00015442-16, NCGC00091349-01, NCGC00091349-02, NCGC00091349-03, NCGC00091349-04, NCGC00091349-05, NCGC00091349-07, NCGC00091349-08, NCGC00254023-01, NCGC00259884-01, NCGC00261221-01, 4CA-0544, 5-Fluoro-2,4-(1H,3H)-pyrimidinedione, AC-11201, AJ-94651, BC227022, CPD000038082, HY-90006, NCI60_001652, SAM002264615, SC-09038, SRI-10792-04, SRI-10792-05, SRI-10792-06, SRI-10792_07, SRI-10792_08, 5-Fluoro-1H-pyrimidine-2,4-dione(5FU), 5-Fluorouracil, >=99% (HPLC), powder, SBI-0050519.P004, 5-Fluoro-1H-pyrimidine-2,4-dione(5-FU), AB1000177, DB-051923, DB-065735, TL8006093, 5-Fluoro-1H-pyrimidine-2,4-dione (5-FU), AM20100252, EU-0100536, FT-0082524, FT-0601511, FT-0707652, ST45025877, 5-Fluoro-1H-pyrimidine-2,4-dione(5-FUra), Fluorouracil, meets USP testing specifications, 51F218, 7375-EP2269989A1, 7375-EP2269994A1, 7375-EP2270008A1, 7375-EP2270018A1, 7375-EP2272827A1, 7375-EP2272832A1, 7375-EP2275102A1, 7375-EP2275412A1, 7375-EP2275413A1, 7375-EP2277876A1, 7375-EP2280012A2, 7375-EP2281563A1, 7375-EP2281815A1, 7375-EP2287156A1, 7375-EP2289892A1, 7375-EP2292233A2, 7375-EP2292614A1, 7375-EP2292615A1, 7375-EP2292617A1, 7375-EP2295416A2, 7375-EP2295426A1, 7375-EP2295427A1, 7375-EP2298748A2, 7375-EP2298768A1, 7375-EP2298772A1, 7375-EP2298780A1, 7375-EP2301928A1, 7375-EP2301933A1, 7375-EP2305219A1, 7375-EP2305243A1, 7375-EP2305640A2, 7375-EP2305642A2, 7375-EP2305671A1, 7375-EP2305689A1, 7375-EP2308833A2, 7375-EP2308839A1, 7375-EP2308855A1, 7375-EP2308861A1, 7375-EP2311807A1, 7375-EP2311808A1, 7375-EP2311825A1, 7375-EP2311827A1, 7375-EP2311829A1, 7375-EP2311840A1, 7375-EP2314590A1, 7375-EP2316459A1, 7375-EP2316831A1, 7375-EP2316834A1, 7375-EP2316974A1, 7375-EP2374454A1, C07649, D00584, W-5036, 29507-EP2270008A1, 29507-EP2270505A1, 29507-EP2272827A1, 29507-EP2289892A1, 29507-EP2292234A1, 29507-EP2292617A1, 29507-EP2295426A1, 29507-EP2295427A1, 29507-EP2298305A1, 29507-EP2308861A1, 29507-EP2311842A2, 42164-EP2272827A1, 42164-EP2275420A1, 42164-EP2277565A2, 42164-EP2277566A2, 42164-EP2277567A1, 42164-EP2277568A2, 42164-EP2277569A2, 42164-EP2277570A2, 42164-EP2277876A1, 42164-EP2292280A1, 42164-EP2292614A1, 42164-EP2295412A1, 42164-EP2295413A1, 42164-EP2295416A2, 42164-EP2298748A2, 42164-EP2298764A1, 42164-EP2298765A1, 42164-EP2298778A1, 42164-EP2305642A2, 42164-EP2308833A2, 42164-EP2311808A1, 42164-EP2311829A1, 42164-EP2311840A1, 2(1H)-Pyrimidinone, 5-fluoro-4-hydroxy- (9CI), 4(3H)-Pyrimidinone, 5-fluoro-2-hydroxy- (9CI), 5-Fluorouracil, Vetec(TM) reagent grade, >=99%, W-60379, (5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione, 5-Fluoro-1H-pyrimidine-2,4-dione(5-fluoro uracil), I07-0022, SR-01000075881-1, SR-01000075881-3, SR-01000075881-5, W-202929, 5-Fluoro-1H-pyrimidine-2,4-dione (5-Fluorouracil), BRD-K24844714-001-02-1, Z275128052, 5-Fluoro-1H-pyrimidine-2,4-dione(5-fluorouracil)(5-FU), 5-Fluorouracil, certified reference material, TraceCERT(R), Fluorouracil, European Pharmacopoeia (EP) Reference Standard, Fluorouracil, United States Pharmacopeia (USP) Reference Standard, pyrimidine antimetabolite: inhibits nucleic acid replication; tetratogen, 2,4-Dihydroxy-5-fluoropyrimidine; 5-Fluoro-2,4(1H,3H)-pyrimidinedione; 5-FU, Fluorouracil, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9, 1004-03-1, 4921-97-5, 79108-01-3

ID: 704

InChIKey: GHCZYXUOYFOXIP-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C2=C(C3=C1OC(C=C3)(C)C)OC=C(C2=O)C4=CC(=C(C=C4)O)O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4871
synonyms found at PubChem are:
pomiferin, 572-03-2, UNII-74YIS40APM, NSC5113, 74YIS40APM, MLS002701889, CHEBI:8329, NSC-5113, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one, NSC 5113, Spectrum_000295, AI3-22130, AC1Q6NKZ, Spectrum2_000799, Spectrum3_000685, Spectrum4_001808, Spectrum5_000515, NCIStruc1_001168, NCIStruc2_001049, BSPBio_002409, KBioGR_002419, KBioSS_000775, SPECTRUM201580, DivK1c_000996, SPBio_000938, AC1L1J58, CHEMBL393136, SCHEMBL8059171, CTK5A6455, HMS503G13, KBio1_000996, KBio2_000775, KBio2_003343, KBio2_005911, KBio3_001629, DTXSID00205831, NCI5113, MolPort-003-665-850, NINDS_000996, HMS1923A09, ZINC899897, HY-N4315, CCG-36078, CCG-37331, LMPK12050244, NCGC00013053, MCULE-3476922697, SDCCGMLS-0066466.P001, IDI1_000996, NCGC00013053-02, NCGC00013053-03, NCGC00013053-04, NCGC00013053-05, NCGC00095220-01, NCGC00095220-02, NCGC00095220-03, NCGC00178667-01, NCI60_004233, SMR001565475, CS-0032736, C10519, SR-05000002658, SR-05000002658-1, BRD-K50660510-001-04-0, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one, 4H,2-b:3,4-b']dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-, 4H,8H-Benzo(1,2-b:3,4-b')dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-, 4H,8H-Benzo(1,2-b:3,4-b)dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-

ID: 705

InChIKey: GHEHNICLPWTXJC-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=N)N)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 75626
synonyms found at PubChem are:
4-Aminobenzamidine dihydrochloride, 2498-50-2, p-Aminobenzamidine dihydrochloride, 4-aminobenzimidamide dihydrochloride, 4-Aminobenzenecarboximidamide dihydrochloride, 4-AMINOBENZAMIDINE 2HCL, 4-Amidinoaniline Dihydrochloride, Benzenecarboximidamide, 4-amino-, dihydrochloride, UNII-3C7VNU62AG, Benzamidine, p-amino-, dihydrochloride, EINECS 219-692-2, 3C7VNU62AG, CHEBI:10618, P-AMINOBENZAMIDINE DIHCL, 4-AMINOBENZAMIDINE HCL SALT, ST50825558, 4-aminobenzenecarboxamidine, chloride, chloride, 4-Aminobenzamidinedihydrochloride, [AMINO(4-AMMONIOPHENYL)METHYLENE]AMMONIUM DICHLORIDE, ACMC-209ggc, 4-Aminobenzamidine DiHCl, 4-aminobenzamidine di-hcl, AC1Q39ZW, KSC204E4D, SCHEMBL236095, AC1L2P67, BIMI2126, CHEMBL1562872, P-AMINOBENZAMIDINE 2 HCL, CTK1A4241, DTXSID10179695, GHEHNICLPWTXJC-UHFFFAOYSA-N, MolPort-000-139-962, ZX-AFC000532, 4-AMINOBENZAMIDINE DI, HCL, ACT00225, BCP12270, KS-000009WH, Tox21_500070, ANW-25594, CA-377, MFCD00013001, SBB063615, AKOS008901225, AB01119, AS01988, CCG-221374, CS-W019509, GS-3168, H98A502, LP00070, RL02813, RTR-032697, VZ28291, 4-Aminobenzamidine dihydrochloride, 98%, NCGC00093580-01, NCGC00260755-01, AC-29284, AK-34349, BC213772, BP-13026, BR-34349, LS-27460, 4-AMINOBENZAMINODINE DIHYDROCHLORIDE, 4-aminobenzenecarboximidamide,dihydrochloride, AB0011024, AX8008250, KB-189267, TR-032697, EU-0100070, FT-0617552, ST24032737, A 7148, C-1048, C11628, 4-aminobenzene-1-carboximidamide dihydrochloride, SR-01000075172, I01-2330, SR-01000075172-1, Benzenecarboximidamide, 4-amino-, hydrochloride (1:2), 4-Aminobenzamidine dihydrochloride, BioReagent, suitable for fluorescence, >=99.0% (TLC), MCULE-4344862493

ID: 706

InChIKey: GHKISGDRQRSCII-UHFFFAOYSA-N
SMILES: CN1CC2=C(C=CC3=C2OCO3)C4C1C5=CC6=C(C=C5CC4O)OCO6

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 10147
synonyms found at PubChem are:
CHELIDONINE (+), Chelidonin [German], Chelidoniny [Polish], TNP00274, EINECS 207-504-1, NSC646661, Spectrum_001123, SpecPlus_000569, AC1L1ULB, AC1Q6ZQM, Spectrum2_000585, Spectrum3_000625, Spectrum4_001879, Spectrum5_000478, BSPBio_002190, KBioGR_002381, KBioSS_001603, DivK1c_006665, SCHEMBL679625, SPECTRUM1500824, SPBio_000430, CHEMBL436279, KBio1_001609, KBio2_001603, KBio2_004171, KBio2_006739, KBio3_001690, GHKISGDRQRSCII-UHFFFAOYSA-N, [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-13-methyl-, (5bR,6S,12bS)-, CCG-38508, AKOS024282591, MCULE-7728607823, NSC-646661, NCGC00017335-02, NCGC00017335-03, NCGC00017335-04, NCGC00095635-01, NCGC00095635-02, NCGC00095635-03, AN-45153, LS-52944, SC-19965, ST057180, V0183, BRD-A19527356-001-02-4, 13-methyl-6,7,13,14,12b,5b-hexahydro-2H,10H-1,3-dioxolano[4'',5''-8',7']phenan thridino[4',3'-2,1]benzo[4,5-d]1,3-dioxolen-6-ol

ID: 707

InChIKey: GHMLBKRAJCXXBS-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5054
synonyms found at PubChem are:
resorcinol, 108-46-3, 1,3-Benzenediol, Resorcin, 1,3-Dihydroxybenzene, benzene-1,3-diol, 3-Hydroxyphenol, m-Hydroquinone, m-Dihydroxybenzene, m-Hydroxyphenol, Resorcine, m-Benzenediol, m-Dioxybenzene, Dihydroxybenzol, Resorzin, Developer O, Developer R, Developer RS, Fouramine RS, Fourrine EW, Pelagol RS, Pelagol Grey RS, Resorcinolum, Fourrine 79, Nako TGG, Durafur developer G, Phenol, m-hydroxy-, C.I. Developer 4, Benzene, m-dihydroxy-, C.I. Oxidation Base 31, Rcra waste number U201, Acnomel, Benzene, 1,3-dihydroxy-, Resorcino, Rezamid, Sulforcin, 3-Hydroxycyclohexadien-1-one, Caswell No. 723, Resorcinol, homopolymer, FEMA No. 3589, UNII-YUL4LO94HK, NCI-C05970, RCRA waste no. U201, NSC 1571, C.I. 76505, .alpha.-Resorcinol, Resorcin (JAN), Resorcin (TN), Resorcinol (USP), Resorcinol [USP], 1,3-Benzenediol, homopolymer, CCRIS 4052, HSDB 722, EINECS 203-585-2, UN2876, YUL4LO94HK, EPA Pesticide Chemical Code 071401, BRN 0906905, CHEMBL24147, AI3-03996, CHEBI:27810, GHMLBKRAJCXXBS-UHFFFAOYSA-N, Resorcinol [UN2876] [Poison], NCGC00091501-01, BENZENE,1,3-DIHYDROXY RESORCINOL, DSSTox_CID_1238, DSSTox_RID_76030, DSSTox_GSID_21238, RCO, Rezorsine, Resorcinol (1,3-Dihydroxybenzene), Rodol RS, CAS-108-46-3, Phoroglucin, Eskamel, m-hydroxy-phenol, 3-hydroxy-phenol, 3aqt, 3-Hydroxy phenol, Resorcinol, 8CI, benzen-1,3-diol, 1,3-benzene diol, Resorcine, technical, 1,3-dihyroxybenzene, 1,3-Dihydroxybenzol, Acnomel (Salt/Mix), Eskamel (Salt/Mix), Rezamid (Salt/Mix), phenol derivative, 3, Benzene,3-dihydroxy-, Resorcinol (Resorcin), Sulforcin (Salt/Mix), 1,3-dihydroxy-benzene, PubChem22214, Spectrum_000173, M-Dihydroxybenzene,(S), AC1L1JIF, Spectrum2_001310, Spectrum3_000895, Spectrum4_000990, Spectrum5_001152, ACMC-1BUC4, WLN: QR CQ, bmse000415, D02DBP, EC 203-585-2, Resorcinol, 99% 50g, 1,3-Dihydroxybenzene, XII, NCIOpen2_003867, SCHEMBL15515, KBioGR_001399, KBioSS_000653, Resorcinol, >=98%, FG, Resorcinol, LR, >=99%, 4-06-00-05658 (Beilstein Handbook Reference), KSC174M8L, BIDD:ER0285, DivK1c_000041, SPECTRUM1500527, SPBio_001379, AC1Q791C, Resorcinol, BioXtra, >=99%, ZINC2028, Jsp000731, DTXSID2021238, BDBM26189, CTK0H4685, FEMA 3589, HMS500C03, KBio1_000041, KBio2_000653, KBio2_003221, KBio2_005789, KBio3_001810, KS-00000WDP, Resorcinol, reagent grade, 98%, NSC1571, 4e49, MolPort-000-872-000, NINDS_000041, Resorcinol [UN2876] [Poison], HMS1920P06, HMS2092G07, Pharmakon1600-01500527, 1,3-Dihydroxybenzene (Resorcinol), HY-B0907, NSC-1571, Resorcinol, ReagentPlus(R), 99%, Tox21_111140, Tox21_202417, Tox21_300140, ANW-15944, CCG-39248, LS-464, MFCD00002269, NSC757310, SBB040843, STL185604, AKOS000119813, Resorcinol, ACS reagent, >=99.0%, Tox21_111140_1, 6025-45-2 (di-hydrochloride salt), DB11085, MCULE-7018276061, NSC-757310, RP18955, RTR-001961, TRA0056209, UN 2876, 1,3-Dihydroxybenzene; 1,3-Benzenediol, IDI1_000041, NCGC00091501-02, NCGC00091501-03, NCGC00091501-04, NCGC00091501-05, NCGC00091501-06, NCGC00253918-01, NCGC00259966-01, Resorcinol, p.a., 99.0-100.5%, Resorcinol, tested according to Ph.Eur., 26982-54-7, 4CN-0976, AC-14363, AJ-08122, AN-42882, BC207605, BP-21158, BR-79460, CJ-00074, KB-60339, Resorcinol, SAJ first grade, >=98.0%, SC-19106, ZB000464, SBI-0051505.P003, AB1009335, Resorcinol, JIS special grade, >=99.0%, ST2413782, TR-001961, FT-0606668, R0008, S4579, ST50214427, 3252-EP2270101A1, 3252-EP2280005A1, 3252-EP2289884A1, 3252-EP2298312A1, 3252-EP2311806A2, 3252-EP2314579A1, 6393-EP2289483A1, 6393-EP2371806A1, 6393-EP2372017A1, C01751, D00133, M-6074, TRANSGENIC MODEL EVALUATION (RESORCINOL), AB00052085_03, Resorcinol (Resorcin) 10 microg/mL in Methanol, A801880, SR-05000002092, I01-6006, Q-201666, SR-05000002092-1, BRD-K74190368-001-02-7, F1908-0097, Resorcinol, certified reference material, TraceCERT(R), Z955123646, Resorcinol, European Pharmacopoeia (EP) Reference Standard, TRANSGENIC LEP (RESORCINOL) (SEE ALSO RESORCINOL), Resorcinol, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8, Hymecromone impurity A, European Pharmacopoeia (EP) Reference Standard, RESORCINOL (SEE ALSO TRANSGENIC MODEL EVALUATION (RESORCINOL)), Resorcinol, Pharmaceutical Secondary Standard; Certified Reference Material, 2-[(3,4-Dihydroxy-9,10-dioxo-2-anthryl)methyl-(2-oxido-2-oxoethyl)ammonio]acetate, Resorcinol, meets analytical specification of Ph.??Eur., BP, 98.5-100.5% (calc. to the dried substance)

ID: 708

InChIKey: GHOSNRCGJFBJIB-UHFFFAOYSA-N
SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2540
synonyms found at PubChem are:
Candesartan cilexetil, 145040-37-5, Atacand, Amias, TCV-116, Parapres, Kenzen, TCV 116, Candesartan (Cilexetil), candesartancilexetil, Candesartan cilexetil [USAN], candesartan cilexitil, TCY 116, CANDESARTAN CILEXTIL, CHEMBL1014, CHEBI:3348, C33H34N6O6, 2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate, 1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-, 2-ETHOXY-1-[[2'-(2H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID 1-[[(CYCLOHEXYLOXY)CARBONYL]OXY]ETHYL ESTER, (+-)-1-Hydroxyethyl 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester), 1-(cyclohexoxycarbonyloxy)ethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate, 1-(cyclohexyloxycarbonyloxy)ethyl 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-benzimidazole-7-carboxylate, 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate, 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate, 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, (+-)-, Racanda, Candesartan hexetil, 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate, Spectrum_001707, AC1L1DWQ, DSSTox_CID_239, Spectrum2_000485, Spectrum3_000996, Spectrum4_001124, Spectrum5_001462, CANDESARTAN CILEXETILE, DSSTox_RID_85567, DSSTox_GSID_20239, SCHEMBL40831, BSPBio_002691, KBioGR_001607, KBioSS_002187, MLS004774127, PBCMNDESARTAN CILEXETIL, SPECTRUM1504261, SPBio_000349, GTPL8352, Candesartan cilexetil (Atacand), DTXSID5020239, KBio2_002187, KBio2_004755, KBio2_007323, KBio3_001911, KS-00000IVU, EBD4212, GHOSNRCGJFBJIB-UHFFFAOYSA-N, MolPort-003-666-552, MolPort-020-393-560, HMS1922J09, HMS2093E20, HMS3651I08, Pharmakon1600-01504261, BCP22050, Candesartan cilexetil (JP17/USAN), Tox21_302202, AC-204, BDBM50318907, BG0573, CCG-39530, MFCD00871371, NSC758697, s2037, STL451065, AKOS015894954, AKOS015920180, AB07617, AM90293, AN-7256, BCP9000480, CCG-222334, CS-2893, DB00796, DS-1302, KS-1147, NSC-758697, VA10473, Candesartan cilexetil, >=98% (HPLC), NCGC00095123-01, NCGC00095123-02, NCGC00095123-03, NCGC00255218-01, 1-(cyclohexylocarbonyloxy)ethyl-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-1H-benzimidazole-7-carboxylate, AK-75900, BC209195, BR-75900, HY-17505, LS-32741, SC-12740, SMR003500784, SBI-0206767.P001, AB0012012, AB2000442, TL8000995, 4CH-009595, CAS-145040-37-5, FT-0082579, FT-0602914, ST24030238, A-2005, C07709, D00626, J10436, AB01274805-01, AB01274805_02, AB01274805_03, 040C375, H212/91, L006257, SR-05000001976, Atacand;Amias;Blopress;Ratacand;TCV 116;TCY 116, Camptothecine, Antibiotic for Culture Media Use Only, I06-0090, Q-200786, SR-05000001976-1, BRD-A65671304-001-02-6, BRD-A65671304-001-03-4, Candesartan cilexetil, European Pharmacopoeia (EP) Reference Standard, Candesartan cilexetil, United States Pharmacopeia (USP) Reference Standard, Candesartan cilexetil for peak identification, European Pharmacopoeia (EP) Reference Standard, Candesartan cilexetil for system suitability, European Pharmacopoeia (EP) Reference Standard, Candesartan Cilexetil, Pharmaceutical Secondary Standard; Certified Reference Material, (+/-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[2'-(1H-tetrazol-5-yl) biphenyl-4-yl]methylbenzimidazole-7-carboxylate, (+/-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methylbenzimidazole-7-carboxylate, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethox, 1-(Cyclohexyloxycarbonyloxy)ethyl-2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazol-7-carboxylate, 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate, 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-3-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-benzodiazole-4-carboxylate, 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-benzodiazole-4-carboxylate, 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl] methyl]benzimidazole-4-carboxylate, 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, ( -)-, 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, 2-ETHOXY-1-[[2'-(2H-TETRAZOL-5-YL)-4-BIPHENYLYL]METHYL]-1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID, 2-Ethoxy-1-[2'-(1H-tetrazole-5-yl)-4-biphenylylmethyl]-1H-benzimidazole-7-carboxylic acid 1-(cyclohexyloxycarbonyloxy)ethyl ester, 2-Ethoxy-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester, 2-Ethoxy-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester, 2-ethoxy-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3h-benzoimidazole-4-carboxylic acid 1-cyclohe, RS-1-[[(CYCLOHEXYLOXY)CARBONYL]OXY]ETHYL 2-ETHOXY-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-BENZIMIDAZOLE-7-CARBOXYLATE

ID: 709

InChIKey: GHSDQCKTVPWTLM-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=NN=C(N=N2)C3=CC=C(C=C3)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 269795
synonyms found at PubChem are:
3,6-bis(4-methoxyphenyl)-1,2,4,5-tetrazine, 14141-66-3, NSC111299, AC1Q4XDH, AC1L6N8O, CTK4C2619, DTXSID30296757, ZINC193661, AKOS001690066, MCULE-2926669176, NSC-111299, EU-0015627, 1,2,4,5-Tetrazine,3,6-bis(4-methoxyphenyl)-, SR-01000085103, SR-01000085103-1

ID: 710

InChIKey: GHUUBYQTCDQWRA-UHFFFAOYSA-N
SMILES: CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 60560
synonyms found at PubChem are:
pioglitazone hydrochloride, 112529-15-4, Pioglitazone HCl, 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride, U-72107A, Pioglitazone (hydrochloride), Pioditazone hydrochloride, [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride, NCGC00095131-01, U-72107E, (+-)-5-(p-(2-(5-Ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione monohydrochloride, DSSTox_CID_24203, DSSTox_RID_80116, C19H21ClN2O3S, DSSTox_GSID_44203, Piomed, 5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-thiazolidine-2,4-dione HCl, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride, 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione hydrochloride, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, monohydrochloride, (+-)-, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride, SMR000469167, CAS-112529-15-4, 5-(4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzyl)-thiazolidine-2,4-dione hcl, 5-(4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzyl)-thiazolidine-2,4-dione hydrochloride, 5-[4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzyl]-thiazolidine-2,4-dione hydrochloride, 5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-thiazolidine-2,4-dione hydrochloride, Pioglitazone hydrochloride [USAN], 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione hydrochloride, 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride, Pioglitazone hydrochloride [USAN:USP], AC1L1THE, pioglitazone, hydrochloride, AC1Q6GK5, CHEMBL1715, SCHEMBL21843, C19H20N2O3S.HCl, MLS001306462, MLS001401386, SPECTRUM1504401, CHEBI:8229, DTXSID3044203, Pioglitazone Hydrochloride ,(S), CTK8B3228, GHUUBYQTCDQWRA-UHFFFAOYSA-N, MolPort-003-666-558, MolPort-027-851-177, HMS1922L05, Pioglitazone hydrochloride (Actos), ACT04238, BCP22942, KS-00000IO7, Tox21_111440, Tox21_300584, ANW-42027, CCG-39097, CP0139, MFCD04975446, s2046, AKOS015844016, Tox21_111440_1, AC-1037, CCG-100931, CS-2235, KS-1186, MCULE-1259842295, NC00181, Pioglitazone hydrochloride (JP17/USP), RTR-001112, NCGC00095131-02, NCGC00163128-08, NCGC00254492-01, AA-10090, AN-15335, BC204340, BR-50391, CPD000469167, HY-14601, I868, SAM001246600, SC-19064, BCP0726000151, AB0013914, AB1009260, LS-151328, LS-172192, Pioglitazone hydrochloride, >=98% (HPLC), ST2411660, TL8000362, TR-001112, AM20061770, FT-0082357, FT-0601607, P1901, 112529-15-4 (HCl), A-2403, D00945, J10107, 025P468, A802593, I06-0413, Q-201584, Pioglitazone hydrochloride, European Pharmacopoeia (EP) Reference Standard, [(+-)-5-[[4-[4-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] monohydrochloride, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, hcl, 5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, hydrochloride, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione hydrochloride, 5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione hydrochloride, 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione Hydrochloride, 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride, Pioglitazone for system suitability, European Pharmacopoeia (EP) Reference Standard, Pioglitazone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Pioglitazone hydrochloride, United States Pharmacopeia (USP) Reference Standard, 127676-30-6, 2,4-thiazolidinedione,5-((4-(2-(5-ehtyl-2-pyridinyl)ethoxy)phenyl)methyl)-monohydrochloride, Pioglitazone hydrochioride, AKOS026749830, Pioglitazone hydrochloride, 98% 250mg, Pioglitazone hydrogen chloride

ID: 711

InChIKey: GHXZTYHSJHQHIJ-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2713
synonyms found at PubChem are:
Chlorhexidine Base, GHXZTYHSJHQHIJ-UHFFFAOYSA-N, AC1L1EAQ, Epitope ID:115577, 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(4-chlorophenyl)-3,12-diimino-, HMS3373P16, KS-000010PY, ZINC14768621, AKOS026749998, NCGC00016246-12, FT-0602988, 97703-EP2284172A1, 97703-EP2295410A1, 97703-EP2301939A1, 97703-EP2305662A1, 97703-EP2372017A1, 2-[6-[[amino-[[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine, AC1NS4AD, (1Z)-2-[6-[[amino-[(Z)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine, AC1NSEOA, AC-11801, (1E)-2-[6-[[amino-[(Z)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine, chlorhexidine, 55-56-1, Chlorhexidinum, Chlorhexidin, Nolvasan, Rotersept, Tubulicid, Fimeil, Hexadol, Soretol, Cloresidina, Clorhexidina, Sterilon, Cloresidina [DCIT], Chlorhexidin [Czech], Chlorhexidinum [INN-Latin], Clorhexidina [INN-Spanish], Chlorohexidine, Hibistat, Novalsan, Sterido, Savlon babycare, Sebidin A, Chlorhexidine [INN:BAN], Hibiclens, Peridex, AVAGARD, Chlorhexidine gluconate, Savloclens, Superspray, Hibispray, 1,6-Bis(p-chlorophenyldiguanido)hexane, 1,6-Di(4'-chlorophenyldiguanido)hexane, Oro-Clense, UNII-R4KO0DY52L, 1,6-Bis(5-(p-chlorophenyl)biguandino)hexane, Exidine, Hibiscrub, Hibitane, Periogard, CCRIS 9230, Chlorhexidine (INN), Sodium Houttuyfonamide, C22H30Cl2N10, Dyna-hex, 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide), HSDB 7196, Merfen-incolore (TN), MK-412A, 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, Nolvasan (*Diacetate*), EINECS 200-238-7, CHEMBL790, Lisium (*Dihydrochloride*), BRN 2826432, R4KO0DY52L, 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide), 1,6-Di(N-p-chlorophenyldiguanido)hexane, Dentisept [veterinary] (TN), MLS001332388, CHEBI:3614, Decanoylacetaldehyde Sodium Sulfide, Bioscrub, Hibidil, Microderm, Periochip, Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-, Brian Care, Prevacare R, Steri-Stat, CAS-55-56-1, Cida-Stat, NCGC00016246-03, SMR000857146, Hibiclens (TN), Peridex (TN), N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)], Pharmaseal Scrub Care, 56-95-1, DSSTox_CID_13314, DSSTox_RID_79062, DSSTox_GSID_33314, Q-200828, chlorhexidine diacetate salt, MLS001304094, 1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide], 2,4,11,13-Tetraazatetradecanediimidamide, N,N'-bis(4-chlorophenyl)-3,12-diimino-, N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)], N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca- nediimidamide, N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine, 1-(4-chlorophenyl)-3-[N-[6-[[N-[N-(4-chlorophenyl)carbamimidoyl]carbamimidoyl]amino]hexyl]carbamimidoyl]guanidine, N-(4-chlorophenyl)-1-3-(6-{N-[3-(4-chlorophenyl)carbamimidamidomethanimidoyl]amino}hexyl)carbamimidamidomethanimidamide, SR-01000799135, 1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide), SMR000718621, chlorohex, Merfen-incolore, 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane, Chlorohex (TN), Hibiscrub (TN), Perichlor (TN), Periochip (TN), Prestwick_53, ChloraPrep (TN), Perioxidina (TN), Clorexil (TN), Corsodyl (TN), Peridont (TN), Chlorhexamed (TN), Avagard (TN), Chlorhexidine (1), Dexidin (TN), Exidine (TN), Oronine (TN), Savacol (TN), Clohex (TN), Suthol (TN), Hibidil (Salt/Mix), Hibisol (Salt/Mix), Dejavu-MW (TN), Chlorhexidine diacetate salt hydrate, Hibitane (Salt/Mix), Dentisept [veterinary], Hibiscrub (Salt/Mix), Hibispray (Salt/Mix), NSC526936, Spectrum_000237, Savloclens (Salt/Mix), BIOPATCH (TN), Prestwick0_000143, Prestwick1_000143, Prestwick2_000143, Prestwick3_000143, Spectrum2_000135, Spectrum3_000339, Spectrum4_000277, Spectrum5_001322, Chlorhexidine (free base), D0V4GY, EC 200-238-7, SCHEMBL3984, Periogard Oral Rinse (TN), SOLU-I.V (TN), Chlorhexidine, >=99.5%, BSPBio_000246, BSPBio_001977, KBioGR_000774, KBioSS_000717, 4-12-00-01201 (Beilstein Handbook Reference), MLS001332387, MLS002154209, DivK1c_000761, SPBio_000210, SPBio_002185, BPBio1_000272, DTXSID2033314, BDBM51937, BDBM64773, cid_9552079, KBio1_000761, KBio2_000717, KBio2_003285, KBio2_005853, KBio3_001197, cid_12303047, MolPort-002-541-741, MolPort-006-167-649, NINDS_000761, REGID_for_CID_9552079, BDBM152706, HMS1568M08, HMS2095M08, HMS2233B16, HMS3712M08, HY-B1248, Tox21_110325, Tox21_201404, Tox21_303445, BDBM50170723, GA1676, MFCD00012532, SBB057564, STK089248, AKOS005394319, Tox21_110325_1, CCG-220143, CS-4958, DB00878, EBD2224760, MCULE-4644073142, IDI1_000761, QTL1_000020, NCGC00016246-01, NCGC00016246-02, NCGC00016246-04, NCGC00016246-05, NCGC00016246-06, NCGC00016246-07, NCGC00016246-09, NCGC00016246-13, NCGC00091025-01, NCGC00091025-02, NCGC00091025-04, NCGC00247766-01, NCGC00257242-01, NCGC00258955-01, AK173132, AN-11702, AN-41674, AS-12648, CC-25659, LS-43917, SC-17656, Chlorhexidine, purum, >=99.0% (HPLC), SBI-0051301.P003, AB1003159, AB00053427, C06902, D07668, AB00053427-24, AB00053427-28, AB00053427_29, 009C673, C-22973, 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide, I06-0621, I14-0050, SR-01000799135-5, 1,1''-Hexamethylene bis(5-(p-chlorophenyl)biguanide), BRD-K52256627-300-03-3, BRD-K52256627-300-05-8, SR-01000799135-10, SR-01000799135-11, Chlorhexidine, European Pharmacopoeia (EP) Reference Standard, 1,1'-(Hexane-1,6-diyl)bis[5-(4-chlorophenyl)biguanide] diacetate, Chlorhexidine, United States Pharmacopeia (USP) Reference Standard, Chlorhexidine, Pharmaceutical Secondary Standard; Certified Reference Material, N'',N''''''''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)], N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca-nediimidamide, (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine;hydrochloride, (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine, (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;hydrochloride, (1E)-2-[6-[[azanyl-[(E)-[azanyl-[(4-chlorophenyl)amino]methylidene]amino]methylidene]amino]hexyl]-1-[azanyl-[(4-chlorophenyl)amino]methylidene]guanidine, (1E)-2-[6-[[azanyl-[(E)-[azanyl-[(4-chlorophenyl)amino]methylidene]amino]methylidene]amino]hexyl]-1-[azanyl-[(4-chlorophenyl)amino]methylidene]guanidine;hydrochloride, {[(4-chlorophenyl)amino]iminomethyl}{[(6-{[({[(4-chlorophenyl)amino]iminomethy l}amino)iminomethyl]amino}hexyl)amino]iminomethyl}amine, 111883-36-4, 2-[amino-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexylimino]methyl]-1-(4-chlorophenyl)guanidine, 2-[amino-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexylimino]methyl]-1-(4-chlorophenyl)guanidine;hydrochloride, 328933-19-3, SCHEMBL9931995

ID: 712

InChIKey: GIEHIZKCIZLXLF-UHFFFAOYSA-N
SMILES: C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "SM Anjos" "D Zhang" "Y Luo" "JW Hanrahan" "J Liao" "N Liu" "R Robert" "C Pavel" "GW Carlile"

CID is 1241327
synonyms found at PubChem are:
KM11060, 774549-97-2, KM 11060, KM-11060, 7-chloro-4-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]quinoline, 7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline, 7-chloro-4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)quinoline, 7-chloro-4-{4-[(4-chlorobenzene)sulfonyl]piperazin-1-yl}quinoline, 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline, AC1LOJDH, AC1Q3JAI, D06TCC, Oprea1_790000, GTPL4234, CHEMBL1905600, SCHEMBL15774887, CTK8E8287, KS-00000TTX, DTXSID40361304, MolPort-001-608-277, BCP17185, ZINC1040357, CCG-44815, STK206351, AKOS000424630, CS-5499, MCULE-1021162800, NCGC00378786-01, HY-19970, RT-013447, B7286, KM11060, >=98% (HPLC), SR-01000634629-1, BRD-K32856097-001-01-4, Z31097998, 7-Chloro-4-[4-(4-chloro-benzenesulfonyl)-piperazin-1-yl]-quinoline, 7-chloro-4-[4-(4-chlorobenzenesulfonyl)piperazin-1-yl]quinoline

ID: 713

InChIKey: GIIZNNXWQWCKIB-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5152
synonyms found at PubChem are:
Salmeterol, 89365-50-4, Serevent, Aeromax, Astmerole, Salmeterolum [Latin], Salmeterolum, GR 33343X, SALMATEROL, Salmeterol [USAN:BAN:INN], HSDB 7315, Salmeterol (USAN/INN), 136112-01-1, 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol, 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol, CHEBI:64064, GIIZNNXWQWCKIB-UHFFFAOYSA-N, GR-33343X, (+-)-4-Hydroxy-alpha'-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-m-xylene-alpha,alpha'-diol, (+-)-4-Hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedimethanol, Salmeterol Fluticasone Propionate Mixture, CPD000466295, S 2692, Q-101428, 1,3-Benzenedimethanol, 4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-, (+-)-, 2-(hydroxymethyl)-4-[1-hydroxy-2-({6-[(4-phenylbutyl)oxy]hexyl}amino)ethyl]phenol, 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol, 1,3-Benzenedimethanol, 4-hydroxy-alpha(sup 1)-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-, (+-)-, 1,3-Benzenedimethanol, 4-hydroxy-alpha(sup 1)-(((6-(4-phenylbutoxy)hexyl)amino)methyl-, (+-)-, SMR000466295, SR-01000076139, Salmeterol [USAN:INN:BAN], SN408D, 4-(1-hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol, NCGC00025247-01, Fluticasonepropiponate, AC1L1JPX, Glaxo Wellcome brand of salmeterol xinafoate, Prestwick3_000945, ACMC-1C1VM, DSSTox_CID_3571, D0L5YV, SCHEMBL4767, CHEMBL1263, DSSTox_RID_77087, DSSTox_GSID_23571, Lopac0_001100, BSPBio_000910, GTPL559, MLS000759000, MLS001424322, BPBio1_001002, DTXSID6023571, BDBM25771, CTK4C0163, MolPort-005-933-084, HMS2052H13, HMS2090E17, HMS2097N12, HMS3268K19, HMS3394H13, HMS3714N12, BCP04199, KS-00000L6B, SalMeterol Xinafoate Adduct IMpurity, Tox21_113584, CS0057, STK629186, AKOS005561914, AN-6615, API0004131, CCG-101194, CCG-205176, CS-2815, DB00938, GR 33343 X, GR-33343-X, NC00444, 1,3-Benzenedimethanol, 4-hydroxy-.alpha.1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-, MRF-0000468, NCGC00015938-03, NCGC00025247-02, ACM136112011, BC202639, CC-34358, HY-14302, K590, LS-29869, SAM001247096, SC-23297, SC-67460, CAS-89365-50-4, KB-146003, AB00513972, FT-0600807, FT-0674509, TL80090037, C07241, D05792, AB00513972-07, 365S504, C-21992, L000532, Salmeterol Impurity H (Xinafoate Adduct Impurity), SR-01000076139-2, SR-01000076139-6, BRD-A01320529-001-05-9, 2-hydroxymethyl-4-{1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}phenol, 1,3-Benzenedimethanol,4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-, 5-[2-[6-(4-Phenylbutoxy)hexylamino]-1-hydroxyethyl]-2-hydroxybenzenemethanol, ( inverted question mark) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol; GR 33343X, (inverted question mark) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol, 1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol

ID: 714

InChIKey: GIPLQLQEWXCSIX-UHFFFAOYSA-N
SMILES: CCOC1=CC=CC(=C1)C(=O)C2=C(C(=C(C=C2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4000243
synonyms found at PubChem are:
3,4-DIDESMETHYL-5-DESHYDROXY-3'-ETHOXYSCLEROIN, KBio2_006130, Spectrum_000514, SpecPlus_000562, Spectrum2_001957, Spectrum3_001302, Spectrum4_001583, Spectrum5_000266, BSPBio_002963, KBioGR_002166, KBioSS_000994, SPECTRUM240429, DivK1c_006658, SPBio_002053, AC1N165R, CHEMBL1336287, SCHEMBL12998336, KBio1_001602, KBio2_000994, KBio2_003562, KBio3_002183, CHEBI:108601, CCG-39495, SDCCGMLS-0066955.P001, NCGC00095542-01, NCGC00095542-02, SR-05000002524, (3-ethoxyphenyl)(2,3,4-trihydroxyphenyl)methanone, (3-ethoxyphenyl)-(2,3,4-trihydroxyphenyl)methanone, SR-05000002524-1

ID: 715

InChIKey: GITPCGSPKUQZTE-UHFFFAOYSA-N
SMILES: CCCOC1=C(C=CC(=C1)N)C(=O)OCCN(CC)CC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11078
synonyms found at PubChem are:
Propoxycaine hydrochloride, Ravocaine hydrochloride, Propoxycaine HCl, Propoxycaine (hydrochloride), 550-83-4, Pravocaine hydrochloride, UNII-K490D39G46, WIN 3459, EINECS 208-988-7, Propoxycaine hydrochloride [USP], K490D39G46, 2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate monohydrochloride, 4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride, Propoxycaine hydrochloride (USP), BENZOIC ACID, 4-AMINO-2-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER, MONOHYDROCHLORIDE, C16H26N2O3, NCGC00016505-01, CAS-550-83-4, 2-(diethylamino)ethyl 4-amino-2-propoxybenzoate;hydrochloride, Blockain Hydrochloride, AC1L1WKH, CHEMBL1769, DSSTox_CID_25325, DSSTox_RID_80804, DSSTox_GSID_45325, SCHEMBL24720, Blockaine hydrochloride (TN), MLS002154133, DTXSID6045325, 2-diethylaminoethyl 4-amino-2-propoxybenzoate hydrochloride, HMS1571C20, Pharmakon1600-01505572, HY-B1243, Tox21_110462, NSC760044, AKOS030526159, API0009273, CCG-213485, CS-4955, NSC-760044, LS-36011, SMR001233440, D02099, SR-01000841224, SR-01000841224-2, AC1LAVRI, 2-(4-amino-2-propoxybenzoyl)oxyethyl-diethylazanium chloride

ID: 716

InChIKey: GIXWDMTZECRIJT-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)O)C(=O)O)C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2259
synonyms found at PubChem are:
aurintricarboxylic acid, 4431-00-9, Aluminon free acid, Aluminon, NSC 4056, EINECS 224-628-1, BRN 2228904, MLS002153482, CHEBI:87397, 5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid), Benzoic acid, 5-((3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl)-2-hydroxy-, SMR000326731, 1,4-Cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylene)-6-oxo-, Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, 1,4-Cyclohexadiene-1-carboxylic acid, 3-[bis(3-carboxy-4-hydroxyphenyl)methylene]-6-oxo-, 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid), 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene)bis(2-hydroxybenzoic acid), 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxocyclohexa-2,5-dienylidene)methyl ]-2-hydroxybenzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid, NSC643698, aurin tricarboxylic acid, SR-01000075661, Benzoic acid, 3,3'-((3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene)bis(6-hydroxy-, Benzoic acid, 3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy-, Dupont ATA, Lopac-A-1895, chrome violet CG free acid, AC1L1DA3, AURINTRICARBOXYLICACID, cid_2259, Lopac0_000054, SCHEMBL98495, 4-10-00-04161 (Beilstein Handbook Reference), SPECTRUM1505163, CHEMBL275938, DTXSID9063453, BDBM60996, CTK7I5976, GIXWDMTZECRIJT-UHFFFAOYSA-N, HMS3260K09, 569-58-4 (tri-ammonium salt), KS-00000US4, ZINC3833863, Tox21_500054, GL9736, MFCD00011663, SBB005410, AKOS015969706, CCG-204149, LP00054, MCULE-4200379590, Dupont DA 639 (SD-095345), NCGC00015040-01, NCGC00015040-02, NCGC00015040-03, NCGC00015040-04, NCGC00015040-05, NCGC00015040-06, NCGC00093568-01, NCGC00096052-01, NCGC00096052-02, NCGC00260739-01, 13186-45-3 (tri-hydrochloride salt), LS-56254, O147, SC-88716, ST057219, 63451-31-0 (calcium (2:3) salt), 93480-02-5 (calcium (1:3) salt), EU-0100054, FT-0622509, A 1895, EN300-226544, SR-01000075661-1, SR-01000075661-7, I04-13102, Aurintricarboxylic acid, practical grade, >=85% (titration), powder, 5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxy-benzoic acid, 5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-oxo-cyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxy-benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2-hydroxybenzoic acid, 5-[(3-carboxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)-(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, 857155-55-6, Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl) (3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-

ID: 717

InChIKey: GIYAQDDTCWHPPL-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2446
synonyms found at PubChem are:
bromopride, 4093-35-0, Bromoprida, Valopride, Artomey, Bromopridum, Emepride, Viaben, Bromoprida [Spanish], Bromoprid, Emoril, Viadil, Bromopride [INN:DCF], Bromopridum [INN-Latin], Bromoprida [INN-Spanish], VAL 13081, C14H22BrN3O2, UNII-75473V2YZK, EINECS 223-842-2, 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, BRN 2381893, 4-Amino-5-bromo-N-(2-(diethylamino)ethyl)-o-anisamide, 75473V2YZK, N-(Diethylaminoethyl)-2-methoxy-4-amino-5-bromobenzamide, NCGC00016646-02, CAS-4093-35-0, Benzamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxy-, DSSTox_CID_25383, DSSTox_RID_80841, DSSTox_GSID_45383, o-Anisamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-, Benzamide, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-2-methoxy-, o-ANISAMIDE, 4-AMINO-5-BROMO-N-(2-(DIETHYLAMINO)ETHYL)-, SR-01000841242, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-2-methoxybenzamide, N-Diethylaminoethyl-2-methoxy-4-amino-5-bromobenzamide, 2-Methoxy-4-amino-5-bromo-N,N-diethylaminoethylbenzamide, Movipride (TN), Prestwick_61, Bromopride (INN), Spectrum_001394, Prestwick0_000704, Prestwick1_000704, Prestwick2_000704, Prestwick3_000704, Spectrum2_001527, Spectrum3_001559, Spectrum4_000726, Spectrum5_000970, AC1L1DP2, SCHEMBL54497, BSPBio_000887, BSPBio_003038, KBioGR_000992, KBioSS_001874, MLS002153965, DivK1c_000317, SPECTRUM1503108, SPBio_001314, SPBio_002808, BPBio1_000977, CHEMBL399510, DTXSID0045383, CHEBI:95304, HMS500P19, KBio1_000317, KBio2_001874, KBio2_004442, KBio2_007010, KBio3_002538, GIYAQDDTCWHPPL-UHFFFAOYSA-N, MolPort-003-666-447, NINDS_000317, HMS1570M09, HMS1922E21, HMS2097M09, HMS2230K23, HMS3374M06, HMS3714M09, Pharmakon1600-01503108, 4093-36-1 (di-hydrochloride), HY-B1164, ZINC2038104, Tox21_110543, CCG-39305, NSC758391, AKOS015994598, Tox21_110543_1, API0001767, CS-4764, DB09018, HS-0004, NSC-758391, IDI1_000317, NCGC00016646-01, NCGC00016646-05, NCGC00095309-01, LS-20037, Q937, SMR001233304, SBI-0051774.P002, AB00052316, FT-0663848, D07101, AB00052316_08, SR-01000841242-2, SR-01000841242-3, BRD-K73642618-001-05-9, BRD-K73642618-001-08-3, 4-amino-5-bromo-N-(2-diethylaminoethyl)-2-methoxybenzamide, 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide #, Benzamide, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-2-methoxy- (9CI)

ID: 718

InChIKey: GIYXAJPCNFJEHY-UHFFFAOYSA-N
SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 62857
synonyms found at PubChem are:
FLUOXETINE HYDROCHLORIDE, Prozac, 56296-78-7, Fluoxetine Hcl, Sarafem, 59333-67-4, Flunirin, Fluoxeren, Adofen, Fluctin, Lovan, Fluoxetine (hydrochloride), Equilibrane, Affectine, Alental, Bioxetin, Depreks, Deproxin, Digassim, Felicium, Fluctine, Fludeka, Flufran, Fluneurin, Fluoxac, Fluoxifar, Fluoxil, Flutine, Fluxene, Foxetin, Margrilan, Mitilase, Modipran, Motivone, Nycoflox, Pragmaten, Proctin, Rowexetina, Seronil, Siquial, Tuneluz, Verotina, Zedprex, Cramin, Erocap, Fludac, Flunil, Flutin, Fluxen, Fluxil, Fondur, Fonzac, Lorien, Neupax, Nopres, Oxedep, Prizma, Prodep, Psipax, Sanzur, Saurat, Sinzac, Zactin, Mutan, Mutin, Nuzak, Zepax, Apo-Fluoxentine, Fluox-Puren, Prozac 20, Alzac 20, Fluoxetine hydrochoride, Selfemra, Fluoxetine.HCl, Lilly 110140, Reconcile, CCRIS 6150, HSDB 6633, LY-110140, Fluoxetine, Hydrochloride, EINECS 260-101-2, LY-110,140 hydrochloride, LY 110140, MLS000069361, CHEMBL1201082, Fluoxetine hydrochloride [USAN], N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride, IN1336, CPD000058452, LY110140, SMR000058452, dl-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, HCl, 3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine hydrochloride, Prozac (TN), (+-)-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine hydrochloride, (+-)-N-Methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propylamine hydrochloride, methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine hydrochloride, C17H18F3NO.HCl, (+/-)-N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine, HCl, Profluzac, Methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)ammonium chloride, N-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride, N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride, Propylamine, N-methyl-3-phenyl-3-(p-trifluoromethylphenoxy)-, hydrochloride, (+/-)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, hydrochloride, Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, hydrochloride, (+-)-, N-METHYL-3-[(4-TRIFLUOROMETHYL)PHENOXY]-3-PHENYLPROPYLAMINE HYDROCHLORIDE, N-methyl-3-phenyl-3-{[4-(trifluoromethyl)phenyl]oxy}propan-1-amine hydrochloride, FluoxetineHydrochloride, SR-01000002988, Framex, Prozac;Sarafem, Fluoxetin HCl, Fluoxetine HCl, Fluoxetine, HCl, N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride, Prestwick_798, Fluoxetine hydrochloride [USAN:USP], (S)-N-Methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine, METHYL(3-PHENYL-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)AMINE HYDROCHLORIDE, AC1L1XXD, DSSTox_CID_635, Opera_ID_1538, DSSTox_RID_75706, DSSTox_GSID_20635, SCHEMBL33384, MLS001076338, MLS002222264, SPECTRUM1504173, Fluoxetine hydrochloride, solid, PROZAC(R) HYDROCHLORIDE, DTXSID7020635, CTK8B3427, HY-B0102A, GIYXAJPCNFJEHY-UHFFFAOYSA-N, MolPort-003-666-535, HMS1569H03, HMS1922F07, Pharmakon1600-01504173, 54910-89-3 (Parent), BCP19962, KS-00000JJ6, NPL-2008, Fluoxetine hydrochloride (JAN/USP), Tox21_200182, Tox21_500558, ANW-42507, CCG-39084, KM0299, MFCD00214288, NSC714457, NSC758685, Prozac; LY-110,140 hydrochloride, s1333, AKOS015894939, AB04860, AC-1697, CS-1838, KS-1061, LP00558, LS-7403, NC00715, NSC-714457, NSC-758685, RL04127, TRA0057937, TRA0075235, (+/-)-FLUOXETINE HYDROCHLORIDE, TRA-0205161, NCGC00093943-01, NCGC00093943-02, NCGC00093943-03, NCGC00093943-04, NCGC00093943-05, NCGC00257736-01, NCGC00261243-01, AN-14688, AN-40216, BC208532, LS-31041, SAM002589965, SC-12129, SC-53387, AB2000053, CAS-56296-78-7, LS-185085, EU-0100558, F-132, F0750, FT-0626490, FT-0652216, ST24047216, D00823, J10277, 910F893, I06-079, I06-0079, J-521372, SR-01000002988-2, SR-01000002988-4, SR-01000002988-9, Z1741982921, Fluoxetine hydrochloride, VETRANAL(TM), analytical standard, Fluoxetine Hydrochloride 1.0 mg/ml in Methanol (as free base), Fluoxetine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Fluoxetine hydrochloride, European Pharmacopoeia (EP) Reference Standard, BENZENEPROPANAMINE, N-METHYL-G-[4-(TRIFLUOROMETHYL)PHENOXY]-, HYDROCHLORIDE (1:1), Fluoxetine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Fluoxetine hydrochloride, United States Pharmacopeia (USP) Reference Standard, METHYL(3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPYL)AMINE, CHLORIDE, N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1), N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propylamine Hydrochloride, (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine, hydrochloride, Fluoxetine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, AC1LCWCY, AKOS015896352, I06-2071, hydron; N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; chloride

ID: 719

InChIKey: GJAWHXHKYYXBSV-UHFFFAOYSA-N
SMILES: C1=CC(=C(N=C1)C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1066
synonyms found at PubChem are:
quinolinic acid, Pyridine-2,3-dicarboxylic acid, 2,3-pyridinedicarboxylic acid, 89-00-9, quinolinate, Pyridine-2,3-dicarboxylate, UNII-F6F0HK1URN, AI3-63017, 2,3-PyridinedicarboxylicAcid, 339155-13-4, EINECS 201-874-8, pyridine-2,3-carboxylate, NSC 13127, F6F0HK1URN, CHEMBL286204, 2,3-pyridine dicarboxylic acid, CHEBI:16675, GJAWHXHKYYXBSV-UHFFFAOYSA-N, Pyridin-2,3-dicarbonsaeure, 2,3-pyridinedicarboxylate, SMR000112287, 2,3-pyridindicarbons, SR-01000075472, HSDB 7511, PubChem8035, Pyridinedicarboxylicacid, Spectrum_001525, Tocris-0225, pyridinedicarboxylic acid, ACMC-1CIWY, AC1L1ANH, pyridine carboxylate, 6c, Spectrum2_000929, Spectrum3_001502, Spectrum4_000336, Spectrum5_001170, Lopac-P63204, bmse000219, D0L8CF, EC 201-874-8, AC1Q1GY6, DSSTox_CID_21327, DSSTox_RID_79688, DSSTox_GSID_41327, Lopac0_000989, Oprea1_139764, SCHEMBL69230, BSPBio_003143, KBioGR_000711, KBioSS_002005, KSC199O4N, MLS001332417, MLS001332418, MLS002153210, TPC-PY101, DivK1c_000773, SPECTRUM1502102, pyridine-2,3-dicarboxlic acid, SPBio_000838, AC1Q73P5, pyridine-5,6-dicarboxylic acid, DTXSID8041327, BDBM26115, CTK0J9746, HMS502G15, KBio1_000773, KBio2_002005, KBio2_004573, KBio2_007141, KBio3_002643, KS-00000CBY, MolPort-000-140-640, NINDS_000773, Pyridine-2 3-Dicarboxylic Acid, 2,3-Pyridinedicarboxylic Acid-d3, HMS1921J12, HMS2267B04, HMS3263E19, HMS3266C15, ZINC331671, NSC13127, NSC18836, 87314-99-6 (strontium salt), Tox21_302051, Tox21_500989, ANW-39203, BBL007601, CCG-39677, NSC-13127, NSC-18836, NSC403247, PDSP1_000133, PDSP2_000132, SBB040573, STK365157, 2,3-Pyridinedicarboxylic acid, 99%, AKOS000119760, AM81291, CS-W020665, DB01796, FG-0461, LP00989, LS20272, MCULE-7041185901, NSC-403247, RP22971, RTC-063613, TRA0001180, CAS-89-00-9, IDI1_000773, MLS-0411909, NCGC00015865-01, NCGC00015865-02, NCGC00015865-03, NCGC00015865-04, NCGC00015865-05, NCGC00015865-06, NCGC00015865-07, NCGC00015865-08, NCGC00024506-01, NCGC00024506-02, NCGC00024506-03, NCGC00024506-04, NCGC00024506-05, NCGC00024506-06, NCGC00255468-01, NCGC00261674-01, 18970-62-2 (copper(2+) salt), 28605-84-7, AC-11734, AJ-19446, AN-42454, BC203300, BR-50219, KB-60133, SC-07191, 2,3-Pyridinedicarboxylic acid (8CI,9CI), MLS-0411909.P016, AB1001981, DB-016184, HY-100807, LS-131173, ST2413775, TC-063613, TL8005760, B6228, EU-0100989, FT-0609764, FT-0689818, P0550, ST50213959, 2,3-Pyridinedicarboxylicacid,labeledwithtritium, 89Q009, A10681, C03722, M-5995, P63204, AC-907/25014157, J-019373, Q-201654, SR-01000075472-1, SR-01000075472-3, Z57160166, F2191-0231, 2,3-Pyridinedicarboxylic acid, Vetec(TM) reagent grade, 98%, InChI=1/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12

ID: 720

InChIKey: GJOHLWZHWQUKAU-UHFFFAOYSA-N
SMILES: CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2.OP(=O)(O)O.OP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6135
synonyms found at PubChem are:
primaquine diphosphate, 63-45-6, PRIMAQUINE PHOSPHATE, Primaquine bisphosphate, Primaquine (Diphosphate), Primaquine bis(phosphate), CCRIS 1946, EINECS 200-560-8, NSC 149765, 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline diphosphate, 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-, phosphate (1:2), 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline phosphate (1:2), DSSTox_CID_25248, DSSTox_RID_80773, DSSTox_GSID_45248, (+-)-8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline phosphate (1:2), 1,4-Pentanediamine, N(sup 4)-(6-methoxy-8-quinolinyl)-, phosphate (1:2), Quinoline, 8-((4-amino-1-methylbutyl)amino)-6-methoxy-, phosphate (1:2), 1,4-Pentanediamine, N(sup 4)-(6-methoxy-8-quinolinyl)-, (+-)-, phosphate (1:2), SR-05000001864, NCGC00178754-06, Primaquine phosphate [USP], Primaquine phosphate [USAN], C15H21N3O.2H3O4P, Primaquine (TN), Prestwick_406, 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine; phosphoric acid, PubChem15391, AC1L1LVF, CAS-63-45-6, NCGC00016284-01, PRIMACHINE PHOSPHATE, SCHEMBL41096, 90-34-6 (Parent), CHEMBL43128, Primaquine bisphosphate, 98%, SPECTRUM1500500, DTXSID6045248, bis(phosphoric acid); primaquine, HMS502I08, Primaquine phosphate (JAN/USP), C15H21N3O.2H3PO4, GJOHLWZHWQUKAU-UHFFFAOYSA-N, MolPort-003-666-267, HMS1569O14, HMS1920J18, HMS2092A19, HMS2096O14, HMS3652B19, HMS3713O14, Primaquine bisphosphate, 98% 1g, Tox21_110350, CCG-40283, CP0101, AKOS026749962, Tox21_110350_1, CS-3875, MCULE-4488548921, NE35433, NCGC00094767-01, NCGC00094767-02, AN-41858, AS-13148, H449, HY-12651, LS-141315, ST24048764, D02126, 013P166, SR-05000001864-1, SR-05000001864-3, SR-05000001864-7, 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline diphosphate, 8-(4-Amino-1-methylbutylamino)-6-methoxyquinolinediphosphate, N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine; phosphoric acid, N4-(6-methoxyquinolin-8-yl)pentane-1,4-diamine bis(phosphate), 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-, phosphate (1:2) (9CI), 8-?(4-?Amino-?1-?methylbutylamino)?-?6-?methoxyquinoline diphosphate salt, N-(5-aminopentan-2-yl)-6-methoxyquinolin-8-amine; bis(phosphoric acid), Primaquine diphosphate, European Pharmacopoeia (EP) Reference Standard, Primaquine phosphate, United States Pharmacopeia (USP) Reference Standard, N4-(6-METHOXYQUINOLIN-8-YL)PENTANE-1,4-DIAMINE; BIS(PHOSPHORIC ACID), AKOS024370832, ST51006727, (4-amino-1-methylbutyl)(6-methoxy(8-quinolyl))amine, phosphoric acid, phosphor ic acid

ID: 721

InChIKey: GJQPMPFPNINLKP-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3038
synonyms found at PubChem are:
dichlorphenamide, Diclofenamide, 120-97-8, Dichlofenamide, 4,5-dichlorobenzene-1,3-disulfonamide, Dichlorophenamide, Daranide, Dichlorphenamid, Antidrasi, Glauconide, Glaucol, Oratrol, Diclofenamid, Diclofenamida, Diclofenamidum, Barastonin, Glafco, Glajust, Glaumid, 4,5-Dichloro-m-benzenedisulfonamide, 1,3-Benzenedisulfonamide, 4,5-dichloro-, Diclofenamidum [INN-Latin], 1,3-Disulfamoyl-4,5-dichlorobenzene, 4,5-Dichloro-1,3-disulfamoylbenzene, Diclofenamida [INN-Spanish], 1,3-Disulfamyl-4,5-dichlorobenzene, Dasanide, Keveyis, 3,4-Dichloro-5-sulfamylbenzenesulfonamide, Dichlorphenamide [BAN], CB 8000, UNII-VVJ6673MHY, Daranide (TN), m-Benzenedisulfonamide, 4,5-dichloro-, 4,5-Dichloro-1,3-benzenedisulfonamide, Dichlorphenamide (Diclofenamide), HSDB 3267, Dichlorphenamide (USP), Dichlorphenamide [USP], Dichlorophenamide (DCP), CHEMBL17, EINECS 204-440-6, BRN 2703329, VVJ6673MHY, CHEBI:101085, GJQPMPFPNINLKP-UHFFFAOYSA-N, 4,5-Dichloro-m-benzendisulfonamide, NCGC00016371-01, CAS-120-97-8, 4,5-Dichloro-benzene-1,3-disulfonic acid diamide, W-108466, I7A, 120D978, C6H6Cl2N2O4S2, sulfonamide 4, 2pou, Prestwick_1071, Diclofenamide [INN], Dichlorophenamide, DCP, PubChem22279, Prestwick0_000809, Prestwick1_000809, Prestwick2_000809, Prestwick3_000809, DSSTox_CID_2922, D0J4GO, D0R0QE, Diclofenamide (JP15/INN), Diclofenamide (JP17/INN), DSSTox_RID_76789, DSSTox_GSID_22922, BSPBio_000677, MLS002154010, SCHEMBL112376, Dichlorphenamide(Diclofenamide), SPBio_002598, AC1L1F18, BPBio1_000745, GTPL6807, Merck Brand of Dichlorphenamide, DTXSID1022922, BDBM10883, CTK6G6454, Llorens Brand of Dichlorphenamide, MolPort-004-285-635, HMS1570B19, HMS2097B19, HMS2236I07, HMS3373G04, HMS3655H06, HMS3714B19, ZINC896918, BCP22591, EX-A1311, HY-B0397, 4,5-dichloro-3-benzenedisulfonamide, Tox21_110401, RW3382, s2177, SBB058142, AKOS015899860, API0002217, CCG-220809, CS-2491, DB01144, MCULE-4570158631, 4,5-Dicholorobenzene-1,3-disulfonamide, KS-00001F78, NCGC00016371-02, NCGC00016371-04, NCGC00016371-05, NCGC00016371-06, AC-25007, AN-43370, BC221062, LS-30043, SMR001233338, ZB015115, 4,5-Dichloro-1,3-benzenedisulfonamide #, AB0108325, AB2000539, FT-0084528, FT-0648264, ST51014977, 120-97-8,76382-13-3(disodiumsalt), A21072, C07459, D00518, SR-01000841825, SR-01000841825-2, BRD-K71499074-001-03-8, I14-11391, Diclofenamide; 4,5-Dichloro-benzene-1,3-disulfonic acid diamide, Dichlorphenamide, United States Pharmacopeia (USP) Reference Standard

ID: 722

InChIKey: GKAJCVFOJGXVIA-DXKBKAGUSA-N
SMILES: COC1=C(C=C(C=C1)/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 637213
synonyms found at PubChem are:
rhapontin, Rhaponticin, 155-58-8, Ponticin, Rhaponiticin, UNII-K691M2Z08V, NSC 43321, CHEBI:8824, K691M2Z08V, (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(3-hydroxy-4-methoxy-phenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol, 3,3 inverted exclamation marka,5-Trihydroxy-4 inverted exclamation marka-methoxystilbene 3-O-|A-D-glucoside, Rhaponticin,(S), 3-Hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)vinyl)phenyl-beta-D-glucopyranoside, 3-hydroxy-5-[2-(3-hydroxy-4-methoxyphenyl)vinyl]phenyl-beta-d-glucopyranoside, (2S,3R,4S,5S,6R)-2-(3-hydroxy-5-(3-hydroxy-4-methoxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, C21H24O9, Rhapontin (8CI), EINECS 205-845-0, Rhapontigenin, 3-beta-D-glucopyranoside, 4'-Methoxy-3,3',5-stilbenetriol-3-glucoside, AC1LCTQS, Glucopyranoside, rhapontigenin-3, beta-D-, Spectrum5_001757, rhapontin from rhubarb root, BSPBio_002946, MLS002207294, Rhapontin, analytical standard, SCHEMBL160068, CHEMBL109266, CHEBI:92176, HMS503I09, b-D-Glucopyranoside,3-hydroxy-5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenyl, GKAJCVFOJGXVIA-DXKBKAGUSA-N, MolPort-003-666-052, 4'-methoxy-3,3',5-stilbenetrol, ZINC3983954, CCG-38881, LMPK13090002, AKOS016034205, Rhapontigenin 3-beta-D-glucopyranoside, 3-Hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)ethenyl)phenyl-beta-D-glucopyranoside, IDI1_001004, NCGC00178379-01, AN-44055, SC-17130, SMR001306806, V0346, C10288, 155R588, SR-05000002217, Q-100184, SR-05000002217-2, BRD-K10098805-001-02-0, 3,3',5-trihydroxy-4'-methoxystilbene 3-o-|A-d-glucoside, 3,3',5-trihydroxy-4'-methoxy-stilbene 3-o-beta-d-glucoside, .beta.-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenyl, 3-hydroxy-5-[(E)-2-(3-hydroxy-4-methoxyphenyl)vinyl]phenyl beta-D-glucopyranoside, beta-D-Glucopyranoside, 3-hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)ethenyl)phenyl (9CI), beta-D-glucopyranoside, 3-hydroxy-5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenyl, (2S,3R,4S,5S,6R)-2-(3-hydroxy-5-((E)-3-hydroxy-4-methoxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol, (2S,3R,4S,5S,6R)-2-{3-Hydroxy-5-[(E)-2-(3-hydroxy-4-methoxy-phenyl)-vinyl]-phenoxy}-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol

ID: 723

InChIKey: GKEGFOKQMZHVOW-UHFFFAOYSA-M
SMILES: C[N+]12CCC(CC1)C(C2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 19004
synonyms found at PubChem are:
CLIDINIUM BROMIDE, 3485-62-9, Quarzan, Clidinium (bromide), Clidinii bromidum, Bromuro de clidinio, Bromure de clidinium, 3-Hydroxy-1-methylquinuclidinium bromide benzilate, Quinuclidinol methylbromide, benzilate, Clidinii bromidum [INN-Latin], Bromure de clidinium [INN-French], Bromuro de clidinio [INN-Spanish], EINECS 222-471-3, 1-Methyl-3-(benziloyloxy)quinuclidinium bromide, 3-(Benziloyloxy)-1-methylquinuclidinium bromide, Ro 2-3773, MLS000028560, 3-(2,2-Diphenyl-2-hydroxyethanoyloxy)-quinuclidinium bromide, 1-Methyl-3-benzil-oxyloxy-quinuclidinium bromide, (+-)-3-Hydroxy-1-methylquinuclidinium bromide benzilate, Quinuclidinium, 3-hydroxy-1-methyl-, bromide, benzilate, DSSTox_CID_2835, 1-Azoniabicyclo(2.2.2)octane, 3-((hydroxydiphenylacetyl)oxy)-1-methyl-, bromide, DSSTox_RID_76750, DSSTox_GSID_22835, Quarzan bromide, (1-methyl-1-azoniabicyclo[2.2.2]octan-8-yl) 2-hydroxy-2,2-diphenylacetate bromide, 1-Azoniabicyclo(2.2.2)octane, 3-((hydroxydiphenylacetyl)oxy)-1-methyl-, bromide, (+-)-, 3-{[hydroxy(diphenyl)acetyl]oxy}-1-methyl-1-azoniabicyclo[2.2.2]octane bromide, SMR000058806, SR-01000000078, (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide, Prestwick_71, Clidinium bromide [USAN:INN:BAN], Quarzan (TN), Clidinium bromide [USAN:USP:INN:BAN], Opera_ID_114, clidinium bromide bromide, NCGC00016630-01, CAS-3485-62-9, AC1L2D9C, SCHEMBL99017, SCHEMBL99018, MLS001148169, MLS002222158, Clidinium bromide (USP/INN), SPECTRUM1500192, REGID_for_CID_19004, CHEBI:3744, CHEMBL1200950, DTXSID7022835, C22H26NO3, HMS502C20, 7020-55-5 (Parent), MolPort-003-666-147, HMS1570F05, HMS1920O15, HMS2091E22, HMS2097F05, HMS2230L12, HMS3370H21, HMS3714F05, Pharmakon1600-01500192, HY-B1132, Tox21_110535, CCG-38925, NSC756686, AKOS015895118, Tox21_110535_1, API0002050, CS-4737, KS-1295, MCULE-6671202274, NSC-756686, VA10607, NCGC00018171-06, NCGC00094625-01, NCGC00094625-02, NCGC00094625-03, NCGC00094625-04, SMR000058806CLIDINIUM BROMIDE, AC-13157, AK-48844, AN-20225, AB1008569, AX8001508, KB-276168, LS-143176, FT-0634879, ST51014934, D00716, A822441, I06-0406, J-019784, SR-01000000078-2, SR-01000000078-4, 1-methylquinuclidin-3-yl 2-hydroxy-2,2-diphenylacetate, bromide, (1-methylquinuclidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate bromide, (1-methyl-1-azoniabicy-clo[2.2.2]oct-8-yl) 2-hydroxy-2,2-diphenyl-acetate bro-mide, (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate bromide, (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-oxidanyl-2,2-diphenyl-ethanoate bromide, 3-(2-hydroxy-2,2-diphenylacetoxy)-1-methyl-1-azoniabicyclo[2.2.2]octane bromide, 2-hydroxy-2,2-diphenylacetic acid (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) ester bromide

ID: 724

InChIKey: GKGKBZYMDILCOF-UHFFFAOYSA-N
SMILES: CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)N4CCC5=C4C=C6C(=C5)OCC67CCN(CC7)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11226716
synonyms found at PubChem are:
SB 224289 hydrochloride, SB-224289 hydrochloride, 180084-26-8, UNII-RTX59ZSB74, SB 224289 HCl, sb224289 hydrochloride, SB 224289A, SB-224289A, RTX59ZSB74, CHEBI:64067, 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE, (1'-methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride, 1'-methyl-5-{[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl}-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidinium] chloride, SMR001254111, SR-01000075552, EU-0101173, MLS002172488, MLS006010774, SCHEMBL6926494, SB 224289 (hydrochloride), CHEMBL1256869, DTXSID9042627, AOB1765, MolPort-003-959-515, BCP27864, ABP000460, AKOS024427780, CS-7876, HY-101105A, MCULE-1380259298, NCGC00094430-01, AC-27413, AS-16681, Methanone, (2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)(1,1'-biphenyl)-4-yl)(2,5,6,7-tetrahydro-1'-methylspiro(3H-furo(2,3-f)indole-3,4'-piperidin)-5-yl)-, hydrochloride (1:1), Spiro(2H-furo(2,3-f)indole-3(5H),4'-piperidine), 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)(1,1'-biphenyl)-4-yl)carbonyl)-, monohydrochloride, KB-275282, RT-015645, B6641, S-201, ST24033673, J-011498, J-011499, SR-01000075552-1, SR-01000075552-3, (2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl), 1 inverted exclamation marka-Methyl-5-[[2 inverted exclamation marka-methyl-4 inverted exclamation marka-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4 inverted exclamation marka-piperidine] hydrochloride, 1'-Methyl-5-([2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl] carbonyl)-2,3,6,7-tetrahydro-spiro(furo[2,3-f]indole-3,4'-piperidine), 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1 ,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6, 7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride, 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride, 1'-methyl-5-{[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl}-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidine] hydrochloride

ID: 725

InChIKey: GKPNPQODFXMCGO-IFXJQAMLSA-N
SMILES: COC1=C(C=C(C=C1)[C@@H]2[C@H](CC3=C(C=C(C=C3O2)OC)OC)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 182659
synonyms found at PubChem are:
CATECHIN TETRAMETHYLETHER, GKPNPQODFXMCGO-IFXJQAMLSA-N, 51079-25-5, (+)-Catechin tetramethyl ether, Spectrum_000310, SpecPlus_000273, AC1L4BEH, Spectrum2_000164, Spectrum3_000247, Spectrum4_001538, Spectrum5_000076, 3',4',5,7-Tetra-O-methyl-(+)-catechin, 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-3-chromanol #, BSPBio_001634, KBioGR_001976, KBioSS_000790, SPECTRUM210220, DivK1c_006369, SPBio_000027, CHEMBL3039226, SCHEMBL12632524, KBio1_001313, KBio2_000790, KBio2_003358, KBio2_005926, KBio3_001134, CHEBI:114199, ZINC2170446, CCG-40008, SDCCGMLS-0066490.P001, 2H-1-Benzopyran-3-ol, 2-(3,4-dimethoxyphenyl)-3,4-dihydro-5,7-dimethoxy-, (2R-trans)-, NCGC00179132-01, (2R,3S)-5,7,3',4'-tetrakis(methyloxy)flavan-3-ol, BRD-K74727418-001-03-4, (2R)-2alpha-(3,4-Dimethoxyphenyl)-5,7-dimethoxychroman-3beta-ol, (2R,3S)-2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3,4-dihydro-2H-chromen-3-ol, 22425-55-4

ID: 726

InChIKey: GKXKQKUIWCLEFJ-UHFFFAOYSA-M
SMILES: COC1=C[N+](=CC=C1)CCCO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 10560095

ID: 727

InChIKey: GLEVLJDDWXEYCO-UHFFFAOYSA-N
SMILES: CC1=C(C(=C2CCC(OC2=C1C)(C)C(=O)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 40634
synonyms found at PubChem are:
trolox, 53188-07-1, 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, TROLOX C, 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid, 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, EINECS 258-422-8, 56305-04-5, BRN 5052542, CHEBI:82625, GLEVLJDDWXEYCO-UHFFFAOYSA-N, (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (+-)-, Trolox®, Trolox(TM), Prestwick_855, ACMC-20apju, ACMC-1ATBW, Prestwick0_000530, Prestwick1_000530, Prestwick2_000530, Prestwick3_000530, CHEMBL153, SCHEMBL3226, Oprea1_727377, BSPBio_000519, MLS002153860, SPBio_002440, AC1L245A, AC1Q2E15, BPBio1_000571, CTK1H0082, MolPort-001-738-524, HMS1569J21, HMS2096J21, HMS2230A15, HMS3369E20, HMS3713J21, 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLICACID, BCP16474, KS-000015YX, ANW-31653, BDBM50359629, GEO-03688, MFCD00006846, SBB005933, AKOS015856256, API0004530, CCG-207912, CS-8035, MCULE-8649288753, RTR-018812, TRA0085345, NCGC00179534-01, AK116067, AS-30121, CC-22776, LS-39163, SC-94697, SMR001233218, ST057520, AX8109302, DB-052268, HY-101445, KB-248834, TR-018812, FT-0621156, C-30819, SR-01000841227, SR-01000841227-2, BRD-A17846016-001-03-0, BRD-A17846016-001-07-1, 6-hydroxy-2,5,7,8-tetramethychroman-2-carboxylic acid, 6-Hydroxy-2,5,7,8-tetramethyl-2-chromancarboxylic acid, I14-105380, 6-Hydroxy-2,5,7,8-tetramethyl-2-chromanecarboxylic acid #, 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid, 6-hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid, (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)carboxylic acid, (+/-)- 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, (+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 97%, 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid, 2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzo-pyran-2-carboxylic Acid, 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid, 6-hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid

ID: 728

InChIKey: GLFIGGLPOXATJW-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1NC2=CC=CC=C2[N+](=O)[O-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 618469
synonyms found at PubChem are:
GLFIGGLPOXATJW-UHFFFAOYSA-N, 2-methoxy-N-(2-nitrophenyl)aniline, N-(2-Methoxyphenyl)-2-nitroaniline, 2-Methoxy-2'-nitrodiphenylamine, AC1LDH8Q, SCHEMBL4940856, MolPort-008-429-782, 2-Nitro-N-(2-methoxyphenyl)aniline, STL432209, ZINC32264713, (2-methoxyphenyl)(2-nitrophenyl)amine, AKOS005209040, MCULE-4074190956, N-(2-Methoxyphenyl)-2-nitroaniline #, N-(2-methoxyphenyl)-N-(2-nitrophenyl)amine

ID: 729

InChIKey: GLKCOBIIZKYKFN-UHFFFAOYSA-N
SMILES: C1=NC2=C(NC1=O)NC(=NC2=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 10729
synonyms found at PubChem are:
Isoxanthopterin, 2-Amino-4,7-dihydroxypteridine, 529-69-1, Ranachrome 4, 2-Aminopteridine-4,7-diol, 2-Amino-4,7(3H,8H)-pteridinedione, 2-AMINO-4,7(1H,8H)-PTERIDINEDIONE, EINECS 208-469-5, NSC 118090, 2-Amino-4,7-pteridinediol, 4,7(3H,8H)-Pteridinedione, 2-amino-, CHEBI:16713, NSC118090, 2-Aminopteridine-4,7(1H,8H)-dione, 2-amino-1,8-dihydropteridine-4,7-dione, 4,7(1H,8H)-Pteridinedione, 2-amino-, 4,7(1H,8H)-Pteridinedione, 2-amino- (9CI), W-202999, 7-hydroxypterin, Isoxanthopterin, 97%, Spectrum_000248, SpecPlus_000308, AC1L1VTN, Spectrum4_001242, UNII-XR11PF6TYR, Lopac-I-7388, XR11PF6TYR, Lopac0_000712, KBioGR_001764, KBioSS_000728, 2-amino-pteridine-4,7-diol, DivK1c_006404, CHEMBL464251, SCHEMBL1331103, SCHEMBL9148336, CTK8G0404, KBio1_001348, KBio2_000728, KBio2_003296, KBio2_005864, DTXSID20200949, GLKCOBIIZKYKFN-UHFFFAOYSA-N, MolPort-003-937-665, MolPort-004-799-633, HMS3262O05, 4,8H)-Pteridinedione, 2-amino-, Tox21_500712, ACM529691, CCG-40096, Isoxanthopterin, >=97.5%, powder, MFCD00006696, NSC614991, ZINC14419577, 2-amino-3H,8H-pteridine-4,7-dione, 2-aminopteridine-4,7(3H,8H)-dione, AKOS024327289, AKOS027320489, Isoxanthopterin, >=97.5% (HPLC), API0003051, FCH1118695, LP00712, MCULE-3517565148, NSC-118090, NSC-614991, VZ23604, 4,7(3H,8H)-Pteridinedione,2-amino-, NCGC00015564-01, NCGC00015564-02, NCGC00015564-03, NCGC00015564-04, NCGC00094062-01, NCGC00094062-02, NCGC00261397-01, 2-amino-3,8-dihydropteridine-4,7-dione, 2-Amino-4,7(1H,8H)-pteridinedione #, NCI60_000432, SC-48731, 2-azanyl-1,8-dihydropteridine-4,7-dione, DB-020417, LS-126307, EU-0100712, FT-0632314, ST50451823, C03975, I 7388, 2-amino-1,4,7,8-tetrahydropteridine-4,7-dione, A829331, SR-01000075227, SR-01000075227-1, 2-Amino-4,7-dihydroxy-1,3,5,8-tetraazanaphthalene, 2- degrees +/->>u-4,7- paragraph signthornoC>>umicroua currency, 2- degrees +/->>u-4,7-microua currency paragraph signthorn (1/4), 2- degrees +/->>u-4,7- paragraph signthornoC>>u-1,3,5,8-EAmicro feminineOOYA, 2-Amino-4,7-dihydroxy-1,3,5,8-tetraazanaphthalene, 2-Amino-4,7-dihydroxypteridine

ID: 730

InChIKey: GLMUPSMDHQHUED-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"AA Shelat" "H Yang" "T Ma" "LJ Galietta" "VS Gopinath" "GL Lukacs" "K Du" "AS Verkman" "RK Guy" "C Folli" "N Pedemonte" "A Taddei"

CID is 722862
synonyms found at PubChem are:
CHEMBL209937, 2-[(2-methylbenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, AC1LF4HZ, Oprea1_406206, Oprea1_857326, ARONIS018977, SCHEMBL5453093, MolPort-000-999-154, ZINC127333, BDBM50185106, STK007957, AKOS000291770, MCULE-9702864044, KS-00004B19, BAS 00803292, ST015560, BB0274140, EU-0068219, SR-01000401029, SR-01000401029-1, 2-(2-methylbenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, 2-[(2-methylphenyl)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbox amide, 2-{[(2-methylphenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

ID: 731

InChIKey: GLVAUDGFNGKCSF-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1)C(=S)N=CN2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4071
synonyms found at PubChem are:
6-Mercaptopurine, mercaptopurine, 50-44-2, Mercapurin, Purinethol, 6-Thiopurine, Leukerin, Leupurin, Mercaleukin, 6-Thioxopurine, Puri-Nethol, Ismipur, Mern, 6-Thiohypoxanthine, 6-Mercaptopurin, 6-Purinethiol, 7H-purine-6-thiol, Purimethol, Purinethiol, Purine-6-thiol, 3H-Purine-6-thiol, 6 MP, Mercaleukim, 6-MP, 9H-Purine-6-thiol, Mercaptopurina, Mercaptopurinum, 1,9-dihydro-6H-purine-6-thione, Hypoxanthine, thio-, 3,7-dihydropurine-6-thione, 1,7-Dihydro-6H-purine-6-thione, Mercaptopurin, Merkaptopuryna, 6H-Purine-6-thione, 1,7-dihydro-, 6-Merkaptopurin, Purine, 6-mercapto-, 9H-Purine-6(1H)-thione, Mercaptopurine anhydrous, Purine-6(1H)-thione, Xaluprine, Mercaptopurine (VAN), NCI-C04886, Mercaptopurin [German], Merkaptopuryna [Polish], Mercaptopurine (6-MP), 7-Mercapto-1,3,4,6-tetrazaindene, 6-Merkaptopurin [Czech], Mercaptopurine (anhydrous), 1H-Purine, 6-mercapto-, NSC 755, Mercaptopurinum [INN-Latin], Mercaptopurina [INN-Spanish], Thiopurine, thiohypoxanthine, U-4748, Leupu rin, NSC-755, UNII-PKK6MUZ20G, Purinethol (TN), C5H4N4S, CCRIS 2761, NSC755, Mercaptopurine (INN), HSDB 3235, EINECS 200-037-4, PKK6MUZ20G, NCIMech_000025, 9H-Purin-6-yl hydrosulfide, 1,9-dihydropurine-6-thione, CHEBI:2208, MP, GLVAUDGFNGKCSF-UHFFFAOYSA-N, DSSTox_CID_810, M0063, DSSTox_RID_75801, DSSTox_GSID_20810, 157930-13-7, 157930-14-8, AG-670/31547064, Purixan, 6 Mercaptopurine, 6 Thiopurine, CAS-50-44-2, 6 Thiohypoxanthine, PM6, SMR000544948, Mercaptopurine, 6-, Mercaptopurina Wellcome, SR-05000001925, 1H-purine-6(7H)-thione, 6 Mercaptopurine Monohydrate, Mercaptopurine;, Mercaptopurine [USAN:USP:INN], 6-Mercaptoadenine, BW 57 323H, PubChem9680, Leukerin, 99%-Carc, Spectrum_000921, ACMC-1AUNA, Spectrum2_000060, Spectrum3_000491, Spectrum4_000857, Spectrum5_000950, H-Purine-6(1H)-thione, D09UZO, Leukerin, 99% - Carc, AC1LDI73, SCHEMBL3893, CHEMBL1425, BSPBio_001981, KBioGR_001493, KBioGR_002363, KBioSS_001401, KBioSS_002366, KSC270A9L, MLS001066623, MLS001304020, MLS001304953, MLS006011869, ARONIS27054, DivK1c_000493, SPECTRUM1500387, SPBio_000219, Mercaptopurine (Purine analog), GTPL7226, SCHEMBL2790086, 7H-Purin-6-yl hydrosulfide #, 6112-76-1 (monohydrate), DTXSID0020810, SCHEMBL12683725, CHEBI:50667, CHEBI:94796, CTK1H0095, CTK8A7797, HMS501I15, KBio1_000493, KBio2_001401, KBio2_002363, KBio2_003969, KBio2_004931, KBio2_006537, KBio2_007499, KBio3_001481, KBio3_002842, 7-Mercapto-1,4,6-tetrazaindene, cMAP_000033, MolPort-001-783-696, MolPort-001-815-626, MolPort-003-846-751, MolPort-006-167-688, NINDS_000493, Purinethol;6-mercaptopurine;6-MP, 3,7-dihydro-6H-purine-6-thione, 6,7-dihydro-3H-purine-6-thione, HMS1920L07, HMS2091B20, HMS2236L06, HMS3259N03, HMS3369M05, HMS3651G07, HMS3713N10, Pharmakon1600-01500387, Wellcome Brand of 6 Mercaptopurine, Wellcome Brand of 6-Mercaptopurine, ACT11542, EBD16256, KS-000048JV, ZINC4658290, Tox21_111158, Tox21_202591, 6450AJ, ANW-30999, ANW-57555, BBL033743, BDBM50423778, CCG-35344, CCG-39915, EBD540779, LS-141, NSC759614, s1305, SBB037953, STK727062, STL257085, 6-Mercaptopurine, analytical standard, WLN: T56 BM DN FN HNJ ISH, AKOS000170222, AKOS000275858, AKOS005224624, AKOS008901311, AKOS016903205, Tox21_111158_1, AM81386, AN-6979, CM-1232, CS-1499, DB01033, LS20858, MCULE-4811219863, NC00613, NSC-759614, RP21622, RTR-021065, IDI1_000493, Glaxo Wellcome Brand of 6 Mercaptopurine, Glaxo Wellcome Brand of 6-Mercaptopurine, NCGC00091641-02, NCGC00091641-03, NCGC00091641-04, NCGC00094717-01, NCGC00094717-02, NCGC00094717-03, NCGC00094717-05, NCGC00094717-06, NCGC00188973-01, NCGC00260139-01, AC-11464, AJ-51833, AN-24375, AS-13109, BC202313, CPD000544948, GlaxoSmithKline Brand of 6 Mercaptopurine, GlaxoSmithKline Brand of 6-Mercaptopurine, H348, HY-13677, KB-45590, NCI60_041653, SAM002589937, SC-04873, SMR004703503, ST086505, ST086506, SBI-0051437.P004, AB0013000, AB0119973, AB2000041, DB-026398, TR-021065, 4CH-021382, BB 0241023, FT-0083571, FT-0621175, EN300-61517, 1766-EP2270008A1, 1766-EP2272827A1, 1766-EP2272832A1, 1766-EP2277876A1, 1766-EP2292614A1, 1766-EP2292617A1, 1766-EP2295409A1, 1766-EP2295426A1, 1766-EP2295427A1, 1766-EP2298768A1, 1766-EP2298778A1, 1766-EP2308833A2, 1766-EP2308855A1, 1766-EP2308861A1, 1766-EP2314590A1, 1766-EP2316834A1, 1766-EP2374454A1, 50M442, C01756, C02380, D04931, W-5114, 15150-EP2272827A1, 15150-EP2275420A1, 15150-EP2295055A2, 15150-EP2295416A2, 15150-EP2298748A2, 15150-EP2298764A1, 15150-EP2298765A1, 15150-EP2305642A2, 15150-EP2305679A1, 15150-EP2308833A2, 15150-EP2311453A1, 15150-EP2311825A1, 15150-EP2311840A1, 15150-EP2311842A2, 15150-EP2316832A1, 15150-EP2316833A1, 21414-EP2270006A1, 21414-EP2270014A1, 21414-EP2272509A1, 21414-EP2272847A1, 21414-EP2275413A1, 21414-EP2277874A1, 21414-EP2284158A1, 21414-EP2287156A1, 21414-EP2287159A1, 21414-EP2295439A1, 21414-EP2311818A1, 21414-EP2314295A1, AB00171799_05, AB00641894-03, AB00641894-04, AB00641894_05, AB00876276-13, 233D552, 462M721, 599M524, A828129, I14-1716, Purinethol, 6-mercaptopurine, 6-MP, Mercaptopurine, SR-05000001925-1, SR-05000001925-2, W-105961, Purineantimetabolite: inhibits nucleic acid replication, purine antimetabolite: inhibits nucleic acid replication, 1,9-Dihydropurine-6-thione DISCONTINUED, see M225450, 39454-94-9, 5759-99-9, 5818-33-7, 5818-60-0

ID: 732

InChIKey: GLZPCOQZEFWAFX-YFHOEESVSA-N
SMILES: CC(=CCC/C(=C\CO)/C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 643820
synonyms found at PubChem are:
nerol, 106-25-2, cis-Geraniol, Neryl alcohol, (Z)-3,7-dimethylocta-2,6-dien-1-ol, (Z)-Geraniol, (2Z)-3,7-dimethylocta-2,6-dien-1-ol, 2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)-, Nerol (natural), cis-3,7-Dimethyl-2,6-octadien-1-ol, (Z)-3,7-dimethyl-2,6-octadien-1-ol, Z-Geraniol, CHEBI:29452, 2-cis-3,7-Dimethyl-2,6-octadien-1-ol, UNII-38G5P53250, 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-, (2Z)-3,7-Dimethyl-2,6-octadien-1-ol, 3,7-Dimethyl-2,6-octadien-1-ol, cis-, GLZPCOQZEFWAFX-YFHOEESVSA-N, 38G5P53250, DSSTox_CID_6728, DSSTox_RID_78203, DSSTox_GSID_26728, W-108769, FEMA No. 2770, EINECS 203-378-7, 3,7-dimethyl-cis-2,6-octadien-1-ol, CAS-106-25-2, AI3-28202, 3,7-Dimethyl-2,6-octadien-1-ol, (Z)-, Nerol 900, Vernol, 3,7-dimethylocta-2,6-dien-1-ol, (Z)-Nerol, cis-2,6-dimethyl-2,6-octadien-8-ol, NEROL PUR, Nerol, analytical standard, EC 203-378-7, NEROL 90, SCHEMBL19825, AC1LD810, CHEMBL452683, Jsp000569, DTXSID3026728, HSDB 8262, (E)3,7-Dimethyl-Octadien-1-ol, NEROL BRI (98+%) FCC, Tox21_202029, Tox21_300542, BDBM50036946, MFCD00063204, ZINC12405252, AKOS016008578, LMPR0102010010, (E)3,7-dimethyl-2,6-Octadien-1-ol, (Z)3,7-dimethyl-2,6-Octadien-1-ol, (2E)3,7-dimethyl-2,6-octadien-1-ol, (2Z)3,7-dimethyl-2,6-octadien-1-ol, (cis)3,7-dimethyl-2,6-Octadien-1-ol, NCGC00164117-01, NCGC00164117-02, NCGC00164117-03, NCGC00254346-01, NCGC00259578-01, AJ-62183, AK109285, CJ-14044, M755, (2Z)-3,7-dimethyl-1-octa-2,6-dienol, 3,7-Dimethyl-trans-2, 6-octadien-1-ol, (2Z)-3,7-dimethyl-octa-2,6-dien-1-ol, AX8144197, KB-212106, N0077, ST24026690, (2Z)-3,7-Dimethyl-2,6-octadien-1-ol #, cis-3,7-Dimethyl-2,6-octadien-1-ol, 97%, C09871, 3,7-DIMETHYL-2,6-OCTADIEN-1-OL(CIS), 3,7-Dimethyl-Octane-1-ol tetrahydro derivative, A801400, Nerol Solution, 1000 mg/L, (RM, ISO GUIDE 34), cis-3,7-Dimethyl-2,6-octadien-1-ol, >=97%, FCC, FG

ID: 733

InChIKey: GMBQZIIUCVWOCD-UQHLGXRBSA-N
SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 91439
synonyms found at PubChem are:
Smilagenin, Isosarsapogenin, Isosarsasapogenin, (25R)-5beta-Spirostan-3beta-ol, 126-18-1, UNII-GQE3Q7YMVZ, (25R)-Spirostan-3beta-ol, GQE3Q7YMVZ, Spirostan-3-ol, (3b,5b,25R)-, 5beta-Spirostan-3beta-ol, (25R)- (8CI), Spirostan-3-ol, (3beta,5beta,25R)- (9CI), Esmilagenin, Cogane, Smilagenin [INN], (25R)-Spirostan-3.beta.-ol, PYM50028, EINECS 204-775-8, 5.beta.-Spirostan-3.beta.-ol, (25R)-, NSC 93747, PYM 50028, AI3-44895, AC1L3M2V, (25R)-5-spirostan-3-ol, SCHEMBL180194, CHEBI:28933, CTK0H5504, GMBQZIIUCVWOCD-UQHLGXRBSA-N, Spirostan-3-ol,5.beta.,25R)-, NSC93747, ZINC8234226, LMST01080005, NSC-93747, (3beta,5beta,25R)-spirostan-3-ol, 5beta -Spirostan-3beta (25R)--ol, SMP1_000275, CC-34443, C08913, C-22015

ID: 734

InChIKey: GMBQZIIUCVWOCD-WWASVFFGSA-N
SMILES: C[C@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 92095
synonyms found at PubChem are:
Sarsasapogenin, 126-19-2, Parigenin, (25S)-5beta-Spirostan-3beta-ol, Sasarasapogenin, Sarsagenin, sarsapogenin, Sarsasapogenenin, UNII-CFS802C28F, CFS802C28F, CHEBI:15578, (3beta,5beta,25S)-spirostan-3-ol, Spirostan-3-ol, (3b,5b,25S)-, Spirostan-3-ol, (3beta,5beta,25S)- (9CI), Sarsagenin [INN], SR-05000002243, cogan, sarsasopogenin, Sarsapogenine, Sarsasapogenine, Sarsasapogenin;, Parigenin;, (25S)-5-beta-spirostan-3-beta-ol, NSC 1615, EINECS 204-776-3, Sarsasapogenin, 95%, AC1L3NEM, Sarsasapogenin, >=98%, (25S)-Spirostan-3beta-ol, (25S)-5-spirostan-3-ol, (25S)-Spirostan-3|A-ol, SCHEMBL180164, BITH3027, CHEMBL1171146, GMBQZIIUCVWOCD-WWASVFFGSA-N, MolPort-005-932-869, ZX-AFC000149, HY-N0073, ZINC8218968, 2770AC, BDBM50442865, LMST01080007, MFCD00270414, AKOS015960455, ACN-035281, CCG-208441, CS-7949, 4CN-0892, AC-11191, AN-43560, BC201861, SC-15309, LS-193826, 5beta-Spirostan-3beta-ol, (25S)- (8CI), N1451, Resorufin-|A-D-glucuronide sodium salt, 98%, C03963, SR-05000002243-2, SR-05000002243-3, SR-05000002243-4, (1'R,2R,2'S,4'S,5S,7'S,8'R,9'S,12'S,13'S,16'S,18'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo[10.8.0.0?,?.0?,?.0??,??]icosane]-16'-ol

ID: 735

InChIKey: GMDFJIJNFIKGNV-UHFFFAOYSA-N
SMILES: CCCCN1CCC(CC1)N2C3=CC=CC=C3NC2=O.C(=O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 9907039
synonyms found at PubChem are:
NS 521 oxalate, 198969-52-7, 1-(1-Butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine oxalate, EU-0100849, MLS002153322, SCHEMBL5772154, CHEMBL1257076, CTK4E2674, DTXSID60432681, LP00849, NCGC00094177-01, SMR001230735, N 7904, SR-01000076031, SR-01000076031-1, 1-(1-Butyl-piperidin-4-yl)-1,3-dihydro-benzimidazol-2-one-oxalate, 2H-Benzimidazol-2-one, 1-(1-butyl-4-piperidinyl)-1,3-dihydro-,ethanedioate (1:1)

ID: 736

InChIKey: GMGIWEZSKCNYSW-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5284452
synonyms found at PubChem are:
Quercetin dihydrate, 6151-25-3, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one dihydrate, Quercetine dihydrate, Quercetin, Dihydrate, CCRIS 3304, UNII-53B03V78A6, 3,3',4',5,7-Pentahydroxyflavone dihydrate, Quercetin dihydrate (Sophoretin), Flavone, 3,3',4',5,7-pentahydroxy-, dihydrate, 53B03V78A6, NCGC00017056-01, CAS-6151-25-3, DSSTox_CID_1219, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone, DSSTox_RID_76018, DSSTox_GSID_21219, C15H14O9, Quercetin,(S), Prestwick_541, PubChem19976, ACMC-20a8z6, AC1NR4H7, SCHEMBL22103, BMK1-G2, KSC919I6H, CHEMBL1520590, DTXSID9021219, Quercetin dihydrate - Sophoretin, CTK8B9463, BIK9012, MolPort-002-131-742, Quercetin dihydrate, 97% 25g, HMS1569F15, HMS2096F15, HMS3403F09, HMS3656A09, BCP07318, KS-00000Q7H, ZX-AT015955, Tox21_110761, Tox21_201150, 3,3 ,4 ,5,7-Pentahydroxyflavone, ANW-62560, GP1387, MFCD00149487, s2347, SBB058176, 2-(3,4-dihydroxyphenyl)-3,5,7-, AKOS004910448, Tox21_110761_1, trihydroxy-4H-chromen-4-one dihydrate, CCG-208320, LS-1471, NUT0000108, OR17030, RTR-021187, TRA0050187, NCGC00015870-27, NCGC00258702-01, AK101905, AS-13663, H655, AB0013168, AX8233444, KB-221422, FT-0082527, FT-0601606, ST24021688, ST50309238, J10072, A833274, I06-0267, F0001-1629, QUERCETIN DIHYDRATE (SEE ALSOQUERCETIN (117-39-5)), 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one dihydrate, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;dihydrate, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyran-4-one dihydrate, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-onedihydrate, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one, hydrate, hydrate, 2-[3,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one dihydrate, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one, oxamethane, oxamethane, Sophoretin, Meletin, Quercetine, Xanthaurine, Quercetol, Quercitin, 6151-25-3, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one Dihydrate (Quercetin Dihydrate)

ID: 737

InChIKey: GMHKMTDVRCWUDX-UHFFFAOYSA-N
SMILES: CCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4060
synonyms found at PubChem are:
MEPHENYTOIN, Methoin, Mesantoin, Methylphenetoin, Phenantoin, Epiazin, Methyl hydantoin, Fenantoin, Sedantoin, Sedantoinal, Triantoin, Insulton, Metydan, Sacerno, Epilan, 50-12-4, Mesontoin, Phenylethylmethylhydantoin, mephentoin, Mephenytoinum, 3-Ethylnirvanol, Mephenetoinum, Mephenytoine, Mefenitoina, Mesdontoin, 5-Ethyl-3-methyl-5-phenylhydantoin, 3-Methyl-5,5-phenylethylhydantoin, 3-Methyl-5-ethyl-5-phenylhydantoin, Sedantional, Mefenetoin, Gerot-epilan, (+/-)-Mephenytoin, Methyl Phenetoin, 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione, Hydantoin, 5-ethyl-3-methyl-5-phenyl-, Mefenitoina [INN-Spanish], Mephenytoine [INN-French], Mephenytoinum [INN-Latin], 5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione, 5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, NSC-34652, 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, Mephenytoin [USAN:INN], 5-Ethyl-5-fenyl-3-methylhydantoin, Mesantoin (TN), 5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione, HSDB 3581, 5-Ethyl-5-fenyl-3-methylhydantoin [Czech], 3-Methyl-5,5-ethylphenylhydantoin, Mephenytoin (USP/INN), EINECS 200-012-8, NSC 34652, BRN 0017282, (+-)-5-Ethyl-3-methyl-5-phenylhydantoin, GMHKMTDVRCWUDX-UHFFFAOYSA-N, NSC34652, 3-Methyl-5, 5-ethylphenylhydantoin, l-Mephenytoin, (+/-)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (R)-Mephenytoin, 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (+-)-, Phenetoin, Methyl, (+/-)-5-Ethyl-3-methyl-5-phenylhydantoin, SR-05000001478, ydantoin, DL-Mephenytoin, Mephenytoin [USAN:USP:INN:BAN], 5 Ethyl 3 Methyl 5 Phenylhydantoin, (+-)-Mephenytoin, l-3-Methyl-5-ethyl-5-phenylhydantoin, Spectrum_001494, (-)-5-Ethyl-3-methyl-5-phenylhydantoin, AC1L1HBP, Prestwick0_001108, Prestwick1_001108, Prestwick2_001108, Prestwick3_001108, Spectrum4_001094, CHEMBL861, D07RGW, Oprea1_289074, SCHEMBL21766, BSPBio_001216, KBioGR_001508, KBioSS_001974, MLS002154157, 3-Methyl-5-ethyl-5-phenylh, DivK1c_000937, SPBio_003088, BPBio1_001338, CHEBI:6757, GTPL7223, DTXSID9023257, CTK8F2163, HMS502O19, KBio1_000937, KBio2_001974, KBio2_004542, KBio2_007110, MolPort-003-666-498, NINDS_000937, HMS1571M18, HMS2089J22, HMS2098M18, HMS2230E21, HMS3369F15, HMS3715M18, 2, 5-ethyl-3-methyl-5-phenyl-, HY-B1184, Mephenytoin 1.0 mg/ml in Methanol, BDBM50103593, GL1129, MFCD00022407, WLN: T5MVNV EHJ C1 E2 ER, AKOS015962176, API0003306, API0004188, CCG-213191, CS-4793, DB00532, MCULE-6021512202, IDI1_000937, NCGC00165924-01, NCGC00165924-02, (?)-5-Ethyl-3-methyl-5-phenylhydantoin, AC-15964, LS-76188, LS-76189, SMR001233457, MU2276000, AB00052368, (.+/-.)-5-Ethyl-3-methyl-5-phenylhydantoin, BIM-0051837.0001, D00375, AB00052368-07, AB00052368_08, 5-Ethyl-3-methyl-5-phenyl-2,5H)-imidazoledione, 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione, SR-05000001478-1, SR-05000001478-3, 2, 4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, BRD-A83937277-001-03-0, A1073/0050334, 4-ethyl-2-hydroxy-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-5-one, Mephenytoin, United States Pharmacopeia (USP) Reference Standard

ID: 738

InChIKey: GMSNIKWWOQHZGF-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)NC1=O)NC=N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 70639
synonyms found at PubChem are:
3-Methylxanthine, 1076-22-8, 3-Methyl-1H-purine-2,6(3H,7H)-dione, 2,6-Dihydroxy-3-methylpurine, Xanthine, 3-methyl-, 3 MX, 3-methyl-7H-purine-2,6-dione, 3-METHYL XANTHINE, 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-, UNII-WS6X982OEC, 3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, CCRIS 5817, 3-methyl-7H-xanthine, 3,7-Dihydro-3-methyl-1H-purine-2,6-dione, EINECS 214-058-1, CHEMBL619, NSC 515466, WS6X982OEC, CHEBI:62207, GMSNIKWWOQHZGF-UHFFFAOYSA-N, 3-Methyl-3,9-dihydro-purine-2,6-dione, 3-Methyl-3,9-dihydro-1H-purine-2,6-dione, 3-methyl-1,3-dihydropurine-2,6-dione, 3-methyl-3,7(9)-dihydro-purine-2,6-dione, 3-methyl-xanthine, 3-methyl-9H-xanthine, Spectrum_001898, Theophylline Impurity B, 3-methyl-1H-purine-2,6(3H,9H)-dione, SpecPlus_000737, AC1L2EIS, AC1Q6LGD, 3-methyl-3,7-dihydro-1h-purin-2,6-dion, Spectrum2_000502, Spectrum3_001652, Spectrum4_001571, Spectrum5_001544, 3-Methylxanthine, 98%, N(1)-demethyltheophylline, 2-oxo-3-methylhypoxanthine, AC1Q3ZJ4, ACMC-1BT43, Oprea1_233226, Oprea1_288071, BSPBio_003403, KBioGR_002122, KBioSS_002428, KSC492Q5R, BIDD:GT0266, DivK1c_006833, SCHEMBL237146, SPECTRUM1504182, SPBio_000423, ACMC-2098x5, SCHEMBL8663339, Jsp000680, 3-Methyl-3H-purine-2,6-diol, 3-methyl-9H-purine-2,6-dione, CHEBI:62208, CTK3J2858, KBio1_001777, KBio2_002422, KBio2_004990, KBio2_007558, KBio3_002623, KS-00000DPJ, DTXSID90148107, MolPort-000-511-760, MolPort-001-783-700, 1-METHYLXANTHINE (1-MX), 3-Methylxanthine, 98% 250mg, BCP18161, ZERO/005108, ZINC4685854, ANW-15831, BBL012772, BDBM50001515, CCG-39565, GEO-01981, MFCD00005580, NSC515466, SBB002920, STK776266, WLN: T56 BM DN FNVMVJ F1, AKOS002272340, AKOS004120009, AKOS006221835, ZINC100459831, CS-W020049, DS-1280, LS21223, MCULE-1015315695, NSC-515466, RP22873, 3-methyl-3,7-dihydropurine-2,6-dione, 1H-Purine-2, 3,7-dihydro-3-methyl-, NCGC00095330-01, NCGC00095330-02, NCGC00178088-01, 3-Methyl-3,7-dihydro-purine-2,6-dione, AJ-51923, AN-25217, BR-72940, CJ-12209, HY-50723, KB-67712, SC-14084, AB0034663, DB-040769, LS-162544, ST4105010, TC-171085, 3,9-dihydro-3-methyl-1H-purine-2,6-dione, 4CH-013701, AM20080030, FT-0616197, M2073, X8852, C16357, S-2007, 3-Methyl-3,9-dihydro-1H-purine-2,6-dione #, 3-methyl-3,9-dihydro-2H,6H-purine-2,6-dione, 076M228, A801730, I14-4637, J-505016, W-108741, 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl- (9CI), Z1741977122, 3-Methyl-3,9-dihydro-purine-2,6-dione(3-methyl xanthine), 3-Methyl-3,7-dihydro-1H-purine-2,6-dione (3-Methylxanthine), Theophylline Related Compound B, United States Pharmacopeia (USP) Reference Standard

ID: 739

InChIKey: GMVPRGQOIOIIMI-DWKJAMRDSA-N
SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5280723
synonyms found at PubChem are:
Prostaglandin E1, alprostadil, 745-65-3, PGE1, Edex, Muse, Caverject, Prostin VR, Alprostadilum, Prostavasin, Topiglan, Vasaprostan, Femprox, Befar, Alprox-TD, Liprostin, Prostandin, Sugiran, Viridal, Vitaros, PGE1 Oligomer, PGE-1, Befar (TN), Prink (TN), Alista, Prink, FemLife, RayVa, l-Prostaglandin E1, MR-256, Minprog, UNII-F5TD010360, Alprostadil(Caverject), MR 256, CHEMBL495, Prostin VR Pediatric, Prostin VR pediatric (TN), (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, Alprostadil Prostoglandin E1, Lipoprost, Prostivas, 11alpha,15alpha-Dihydroxy-9-oxo-13-trans-prostenoic acid, BML1-F06, (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, CHEBI:15544, PGE1alpha, HEI-507, 9-oxo-11R,15S-dihydroxy-13E-prostaenoic acid, GMVPRGQOIOIIMI-DWKJAMRDSA-N, U-10136, 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid, F5TD010360, (-)-Protaglandin E1, (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid, l-PGE1, Alprostadilum [INN-Latin], 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid, Promostan, (11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid, ONO 1608, EINECS 212-017-2, Prostaglandine E, Caverject Impulse, NSC 165559, Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11alpha,13E,15S)-, homopolymer, CPD000112594, SMR000112594, AI3-62116, U 10136, SR-01000597593, Lipo-alprostadil, 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid, l-3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid, Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11alpha,13E,15S)-, Prostaglandin-E1, Alprostadil(usan), (1R,2R,3R)-3-Hydroxy-2-((E)-(3S)-3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid, Caverject (TN), NCGC00016535-01, 119314-69-1, CAS-745-65-3, Vitaros (TN), (13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate, Alprostadil [USAN:USP:INN:BAN:JAN], Edex (TN), Muse (TN), AC1NQXHQ, 11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid, PGE1;Prostaglandin E1, Prestwick2_001018, Prestwick3_001018, U-10,136, DSSTox_CID_2578, D0I4DQ, D0N2EF, DSSTox_RID_76640, DSSTox_GSID_22578, SCHEMBL33317, BSPBio_001175, BSPBio_001488, MLS000758964, MLS001424250, BIDD:GT0747, BPBio1_001293, GTPL1882, Alprostadil (JP15/USP/INN), Alprostadil (JP17/USP/INN), Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, l-, DTXSID9022578, SYN3025, MolPort-003-939-183, HMS1361K10, HMS1571K17, HMS1791K10, HMS1989K10, HMS2052L11, HMS2090L08, HMS2098K17, HMS3268I09, HMS3402K10, HMS3648O17, HMS3715K17, BCP01740, EX-A1411, HY-B0131, ZINC3813088, Tox21_110482, BDBM50101853, BG0025, LMFA03010134, MFCD00077860, s1508, AKOS015961103, Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11.alpha.,13E,15S)-, AC-6095, BCP9000277, CCG-101188, CS-1905, NC00438, RP17688, IDI1_033958, Prostaglandin E1, >=99.0% (TLC), SMP2_000271, NCGC00025234-02, NCGC00025234-03, NCGC00025234-04, NCGC00025234-05, AS-16360, BC205461, K274, SAM001246840, SAM001246845, SAM001247093, AB0014134, AB2000131, 11,15-Dihydroxy-9-oxoprost-13-en-1-oate, AB00514004, B2154, ST50826271, Alprostadil, meets USP testing specifications, C04741, D00180, Prostaglandin E1, >=98% (HPLC), synthetic, Prostaglandin E1;Edex;Muse;Liprostin;Caverject, AB00514004-06, AB00514004-08, AB00514004_09, 745P653, SR-01000946253, SR-01000597593-1, SR-01000597593-5, SR-01000597593-6, SR-01000946253-1, W-104416, BRD-K52459643-001-06-0, BRD-K52459643-001-10-2, BRD-K52459643-001-17-7, (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoate, (13E)-(15S)-11,15-dihydroxy-9-oxoprost-13-enoic acid, Alprostadil, European Pharmacopoeia (EP) Reference Standard, (13e)-(15s)-11alpha,15-dihydroxy-9-oxoprost-13-enoic acid, (11?,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid, (13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoic acid, 11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (ACD/Name 4.0), 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoate, 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid, Alprostadil, United States Pharmacopeia (USP) Reference Standard, (+)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoate, (+)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoic acid, (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoate, (-)-3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-Cyclopentaneheptanoic acid, Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture, 7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoic acid, 7-[(1r,3r)-3-Hydroxy-2-[(1e,3s)-3-Hydroxyoct-1-En-1-Yl]-5-Oxocyclopentyl]heptanoic Acid, Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, (-)-, Prostaglandin E1, powder, gamma-irradiated, BioXtra, suitable for cell culture, 22299-37-2, 50-83-9, 50865-30-0, 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]hepta noic acid, XPG

ID: 740

InChIKey: GMZVRMREEHBGGF-UHFFFAOYSA-N
SMILES: C1CC(=O)N(C1)CC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4843
synonyms found at PubChem are:
piracetam, 7491-74-9, 2-(2-oxopyrrolidin-1-yl)acetamide, Nootropil, 2-Oxo-1-pyrrolidineacetamide, Nootropyl, Pyracetam, Normabrain, Gabacet, Pyramem, 1-Pyrrolidineacetamide, 2-oxo-, Ciclofalina, Genogris, Pirazetam, Pirroxil, Euvifor, Nootron, 2-Pyrrolidinoneacetamide, 2-Oxo-pyrrolidine acetamide, 2-Pyrrolidoneacetamide, Naofukang [Chinese], 1-Acetamido-2-pyrrolidinone, UCB 6215, 2-(2-oxo-pyrrolidin-1-yl)acetamide, 2-Oxo-pyrrolidin-1-ylacetamide, 2-Ketopyrrolidine-1-ylacetamide, Cl-871, Piracetamum [INN-Latin], UNII-ZH516LNZ10, KT-801, MLS000069719, 2-(2-Oxo-1-pyrrolidinyl)acetamide, EINECS 231-312-7, BRN 1526393, SMR000058196, 2-(2-Oxopyrrolidino)acetamide, ZH516LNZ10, GMZVRMREEHBGGF-UHFFFAOYSA-N, NCGC00015821-02, CAS-7491-74-9, 2-(2-oxidanylidenepyrrolidin-1-yl)ethanamide, DSSTox_CID_24491, DSSTox_RID_80267, DSSTox_GSID_44491, 2-(2-oxopyrrolidinyl)acetamide, Cerebroforte, Piracetamum, Avigilen, Breinox, Naofukang, Nootrop, Axonyl, Geram, SR-01000076071, 2-Pyrrolidone-N-Acetamide, neuracetam, Encetrop, Myocalm, Norzetam, Piracetam [USAN:BAN:INN], Piracetam [USAN:INN:BAN], HSDB 7529, Piracetam,(S), UCB-6215, Prestwick_870, Myocalm (TN), Deshydroxy Oxiracetam, Spectrum_001421, Opera_ID_1766, Prestwick0_000537, Prestwick1_000537, Prestwick2_000537, Prestwick3_000537, Spectrum2_001074, Spectrum3_001523, Spectrum4_000742, Spectrum5_001037, Lopac-P-5295, D0Q4YK, ssAA-I/I(1), AC1L1J2W, cid_4843, Lopac0_000949, Oprea1_512927, SCHEMBL20172, BSPBio_000553, BSPBio_002906, KBioGR_001064, KBioSS_001901, 5-21-06-00360 (Beilstein Handbook Reference), Piracetam (JAN/USAN/INN), CHEMBL36715, DivK1c_000259, SPECTRUM1502195, SPBio_001088, SPBio_002474, 2-(2-ketopyrrolidino)acetamide, BPBio1_000609, GTPL4288, DTXSID5044491, BDBM62877, CHEBI:32010, Cl-781, CTK7D3269, HMS500M21, KBio1_000259, KBio2_001901, KBio2_004469, KBio2_007037, KBio3_002406, MolPort-000-839-314, NINDS_000259, HMS1569L15, HMS1921L12, HMS2092D18, HMS2096L15, HMS2230B24, HMS3262N20, HMS3371G01, HMS3657A05, HMS3713L15, Pharmakon1600-01502195, BCP28414, HY-B0585, KS-00000K5B, ZINC3812874, Tox21_110229, Tox21_301990, Tox21_500949, BBL028161, CCG-39282, MFCD00079246, NSC758191, s3070, SBB086233, STK535612, 2 - Oxo - 1 - pyrrolidineacetamide, AKOS001038683, Tox21_110229_1, 2-(2-Oxo-1-pyrrolidinyl)acetamide #, CS-2774, DB09210, LP00949, MCULE-7645397226, NSC-758191, IDI1_000259, NCGC00015821-01, NCGC00015821-03, NCGC00015821-04, NCGC00015821-05, NCGC00015821-06, NCGC00015821-07, NCGC00015821-08, NCGC00015821-10, NCGC00094253-01, NCGC00094253-02, NCGC00094253-03, NCGC00094253-04, NCGC00255727-01, NCGC00261634-01, AS-13920, BC204713, K282, SC-78454, SBI-0050923.P003, AB0014139, AB1009436, DB-019407, KB-162500, LS-137082, TX-017921, AB00052287, EU-0100949, FT-0636504, ST50182453, Piracetam, VETRANAL(TM), analytical standard, D01914, M-3297, P 5295, 96625-EP2287163A1, 96625-EP2305678A1, AB00052287_12, A838261, AE-641/30117005, I05-0236, SR-01000076071-1, SR-01000076071-4, SR-01000076071-6, W-104408, BRD-K19456237-001-22-7, Z56865289, Piracetam, European Pharmacopoeia (EP) Reference Standard, 2-(2-Oxopyrrolidino)acetamide; 2-Oxo-1-pyrrolidineacetamide, 2-No u-1-ssA inverted question mark(c)IeOOo pound degrees ., Breinox, Dinagen, Lucetam, Nootropil, Nootropyl, Oikamid, and many others

ID: 741

InChIKey: GNMSLDIYJOSUSW-LURJTMIESA-N
SMILES: CC(=O)N1CCC[C@H]1C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 66141
synonyms found at PubChem are:
N-Acetyl-L-proline, 68-95-1, Ac-Pro-OH, Acetylproline, N-Acetylproline, 1-Acetyl-L-proline, Acetyl proline, L-Proline, 1-acetyl-, Acetyl-L-Proline, (S)-1-acetylpyrrolidine-2-carboxylic acid, (2S)-1-acetylpyrrolidine-2-carboxylic acid, UNII-CC8XZ138VZ, CC8XZ138VZ, (S)-1-Acetyl-pyrrolidine-2-carboxylic acid, CHEBI:21560, L-Proline, 1-acetyl- (9CI), GNMSLDIYJOSUSW-LURJTMIESA-N, N7P, Proline, 1-acetyl-, L-, acetyl-proline, 4avs, N-Acetyl Proline, 1-Acetylproline #, EINECS 200-698-9, (s)-n-acetylproline, NSC 280718, PubChem6388, DL-Proline, 1-acetyl-, AC1L24PQ, AC1Q1KD1, (S)-(-)-N-acetylproline, KSC178K1R, MLS000774349, SCHEMBL358379, CHEMBL1234599, CTK0H8518, MolPort-000-000-506, HMS2765I14, ZINC119664, ACT08606, KS-00000A9M, Proline, 1-acetyl-, L- (8CI), ANW-74566, KM1230, AKOS000302142, AKOS001121369, AM82193, CS-W004114, DB03360, MCULE-9915147289, RP22098, (S)-acetyl-pyrrolidine-2-carboxylic acid, AJ-11606, AN-41912, BAS 16579166, DS-13404, KB-47118, SC-06276, SMR000365399, SY008844, AB1007097, DB-055208, ST2402732, TR-022972, A7277, FT-0657941, A44136, 020A837, I14-2783, J-300220, N-Acetyl-L-proline, Vetec(TM) reagent grade, 98%, Q-101648, Z85923459, 4-methoxy-2-methylbenzoic acid;2-methyl-4-methoxybenzoicacid

ID: 742

InChIKey: GNOGSFBXBWBTIG-UHFFFAOYSA-N
SMILES: CC(=O)NC1=C(C=C(C(=C1I)C(=O)O)I)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6806
synonyms found at PubChem are:
Acetrizoic acid, 85-36-9, 3-Acetamido-2,4,6-triiodobenzoic acid, Opacaron, Urokon, Acetrizoesaeure, Urokonic acid, Acide acetrizoique, ACETRIAZOIC ACID, 3-(Acetylamino)-2,4,6-triiodobenzoic acid, UNII-24256BQV7M, EINECS 201-600-7, Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-, BRN 2219129, 3-acetamido-2,4,6-triiodo-benzoic acid, Acido 3-acetilamino-2,4,6-triiodobenzoico, CHEBI:34521, 2,4,6-TRIIODO-3-ACETAMIDOBENZOIC ACID, 24256BQV7M, BENZOIC ACID, 3-ACETAMIDO-2,4,6-TRIIODO-, Acido 3-acetilamino-2,4,6-triiodobenzoico [Italian], 3-Acetamino-2,4,6-triiodobenzoic acid, NCGC00095105-01, DSSTox_CID_2549, DSSTox_RID_76623, DSSTox_GSID_22549, Acetrizoate, CAS-85-36-9, Acetrizoic acid [USP], AcetrizoicAcid, Benzoic acid, 3-(acetamido)-2,4,6-triiodo-, monosodium salt, Spectrum_001759, AC1L1NCG, 129-63-5, Spectrum2_000028, Spectrum3_000988, Spectrum4_001114, Spectrum5_001859, BSPBio_002655, KBioGR_001588, KBioSS_002239, MLS004773977, SCHEMBL433123, SPECTRUM1504142, SPBio_000095, AC1Q5M09, CHEMBL1201327, DTXSID2022549, CTK5F4807, GNOGSFBXBWBTIG-UHFFFAOYSA-, KBio2_002239, KBio2_004807, KBio2_007375, KBio3_001875, GNOGSFBXBWBTIG-UHFFFAOYSA-N, MolPort-001-783-520, HMS1922D11, HMS2093A04, Pharmakon1600-01504142, HY-B1406, KS-000013BP, ZINC3830175, Tox21_111423, CCG-40045, NSC758681, AKOS015902793, Tox21_111423_1, API0000348, CS-4861, DB09347, NSC-758681, NCGC00095105-02, NCGC00095105-03, NCGC00095105-05, AN-42305, CC-07169, LS-35477, SMR003500670, SBI-0206722.P001, AX8007307, DB-019835, A0858, FT-0621816, TL80090825, Benzoic acid,3-(acetylamino)-2,4,6-triiodo-, C14164, D02457, AB01563018_01, 085A369, C-23210, SR-05000001942, SR-05000001942-1, I14-19882, InChI=1/C9H6I3NO3/c1-3(14)13-8-5(11)2-4(10)6(7(8)12)9(15)16/h2H,1H3,(H,13,14)(H,15,16)

ID: 743

InChIKey: GNRIZKKCNOBBMO-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C=C2C(=C1O)C(=O)C3=C(C(=C(C=C3O2)O)OC)CC=C(C)C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281650
synonyms found at PubChem are:
alpha-Mangostin, Mangostin, 6147-11-1, 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, Mangostine, NSC27593, NSC30552, NSC-30552, UNII-U6RIV93RU1, U6RIV93RU1, CHEMBL323197, CHEBI:67547, GNRIZKKCNOBBMO-UHFFFAOYSA-N, 1,3,6-trihydroxy-7-methoxy-2,8-diprenylxanthone, TNP00140, NSC 27593, NSC 30552, NSC 139154, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one, 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one, Q-100010, 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3,3-dimethylallyl)xanthone, 1,3,6-Trihydroxy-7-methoxy-2,8-di(3-methyl-2-butenyl)xanthone, 1,7-bis(3-methylbut-2-enyl)-3,6,8-trihydroxy-2-methoxyxanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one, a-Mangostin, 9H-Xanthen-9-one,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-, Xanthen-9-one,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-, 9H-Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-, AC1NQYTD, Mangostin, a-Mangostin, Spectrum_001726, SpecPlus_000574, Spectrum2_001620, Spectrum3_001297, Spectrum4_001911, Spectrum5_000622, D02ZPE, D06PRC, 4-(4-Aminoethyl)Morpholine, BSPBio_002933, KBioGR_002529, KBioSS_002206, BIDD:ER0576, DivK1c_006670, SCHEMBL354735, SPECTRUM1504015, SPECTRUM1505128, SPBio_001659, CTK8C4814, HSDB 8103, KBio1_001614, KBio2_002206, KBio2_004774, KBio2_007342, KBio3_002153, KS-00000LYA, DTXSID00210420, MolPort-001-736-566, ACT09245, BCP13253, HY-N0328, ZINC5430812, alpha-Mangostin, >=98% (HPLC), ANW-73224, BDBM50214969, CCG-36465, MFCD00135200, NSC-27593, NSC139154, AKOS015912806, AC-6089, CS-6435, DS-3359, MCULE-1080742368, NSC-139154, SDCCGMLS-0066796.P001, NCGC00017251-01, NCGC00017251-02, NCGC00017251-03, NCGC00017251-04, NCGC00017251-05, NCGC00095730-01, NCGC00095730-02, NCGC00095730-03, NCGC00178385-01, 4CN-1087, AJ-54080, AK105375, AN-10378, SC-86167, ST057241, AX8053706, DB-053898, KB-216381, TR-021173, FT-0635997, M2793, N1590, N2590, ST24036751, W2645, C10080, 147M111, A833244, SR-05000002649, I14-4849, SR-05000002649-1, BRD-K11991978-001-02-6, BRD-K11991978-001-03-4, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9-xanthenone, 1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2-enyl)-xanthen-9-one, 2-methoxy-1,7-bis(3-methylbut-2-enyl)-3,6,8-tris(oxidanyl)xanthen-9-one, 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one, 9H-Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-, 9H-Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)- (9CI), 9H-Xanthen-9-one,1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-, Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)- (8CI)

ID: 744

InChIKey: GNUCGROXDZMCJI-UHFFFAOYSA-N
SMILES: CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 33254
synonyms found at PubChem are:
Minaprine dihydrochloride, MINAPRINE HYDROCHLORIDE, Minaprine (dihydrochloride), Minaprine HCl, 25953-17-7, UNII-82Y7NT6DFT, 30038CB, Minaprine hydrochloride [USAN], AGR 620, NSC 305742, 82Y7NT6DFT, CM 30038, MINAPRIN DIHYDROCHLORIDE, 3-(2-Morpholinoethylamino)-4-methyl-6-phenylpyridazine dihydrochloride, 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine dihydrochloride, 4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-, dihydrochloride, N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine dihydrochloride, DSSTox_CID_25864, DSSTox_RID_81184, Morpholine, 4-(2-((4-methyl-6-phenyl-3-pyridazinyl)amino)ethyl)-, dihydrochloride, DSSTox_GSID_45864, Minaprine hydrochloride (USAN), CHEBI:51040, 30038CM, CAS-25953-17-7, Alcas, SR-01000003128, Minaprin diHCl, Prestwick_2, 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine dihydrochloride, C17H22N4O.2HCl, SCHEMBL124092, SPECTRUM1501120, AC1L1P95, CHEMBL1364551, DTXSID2045864, CTK8G1122, HY-B0884A, AOB5323, MolPort-003-666-357, HMS1568M13, HMS1921F21, 25905-77-5 (Parent), KS-00001F9P, Tox21_111355, CCG-39019, MFCD00083410, AKOS030526122, Tox21_111355_1, API0003396, ACM25905775, NCGC00016795-06, NCGC00016795-11, NCGC00094902-01, NCGC00094902-02, LS-92884, SC-62488, Minaprine dihydrochloride, analytical standard, D05040, J-016170, SR-01000003128-3, 4-methyl-N-(2-morpholinoethyl)-6-phenylpyridazin-3-amine dihydrochloride, Morpholine, 4-(2-((4-methyl-6-phenyl-3-pyridazinyl)amino)ethyl)-, dihydrochloride (8CI), AKOS026749868

ID: 745

InChIKey: GNUXVOXXWGNPIV-UHFFFAOYSA-N
SMILES: CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3326
synonyms found at PubChem are:
Famprofazone, 22881-35-2, Famprofazon, Famprofazone [INN:BAN], Famprofazonum [INN-Latin], Famprofazona [INN-Spanish], EINECS 245-284-9, BRN 5768367, C24H31N3O, Antipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-, 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine [French], DSSTox_CID_25435, DSSTox_RID_80877, Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-, DSSTox_GSID_45435, 1,2-Dihydro-1-methyl-4-(1-methylethyl)-5-((methyl(1-methyl-2-phenylethyl)amino)methyl)-2-phenyl-3H-pyrazol-3-one, 3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-, 3H-Pyrazolin-5-one, 4-isopropyl-2-methyl-3-((methyl(alpha-methylphenethyl)amino)methyl)-1-phenyl-, Famprofazona, Famprofazonum, Geodowin, 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one, 3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-((methyl(1-methyl-2-phenylethyl)amino)methyl)-2-phenyl-, 3H-Pyrazol-3-one,1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-, 4-Isopropyl-2-methyl-3- (methyl(alpha-methylphenethyl)amino)methyl -1-phenyl-3-pyrazolin-5-one, 4-Isopropyl-2-methyl-3-{(methyl(alpha-methylphenethyl)amino)methyl}-1-phenyl-3-pyrazolin-5-one, SR-01000838884, NCGC00016769-01, 1,2-Dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-3H-pyrazol-3-one, CAS-22881-35-2, AC1L1FOH, Prestwick0_000703, Prestwick1_000703, Prestwick2_000703, Prestwick3_000703, AC1Q6IH5, BSPBio_000885, MLS002153964, SCHEMBL893453, SPBio_002806, BPBio1_000975, CHEMBL1475693, DTXSID3045435, CHEBI:93799, component of Gewodin (Salt/Mix), CTK4F0380, Famprofazone, analytical standard, GNUXVOXXWGNPIV-UHFFFAOYSA-N, MolPort-003-941-405, HMS1570M07, HMS2097M07, HMS2235J18, HMS3369C14, HMS3714M07, Pharmakon1600-01505773, HY-B1054, Famprofazone 1.0 mg/ml in Methanol, Tox21_110600, 2409AH, BDBM50103614, NSC602800, NSC759244, AKOS015894771, Tox21_110600_1, API0007990, CCG-213983, CS-4576, KS-1356, NSC-602800, NSC-759244, 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine, NCGC00179385-01, NCGC00179385-03, 4-isopropyl-1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-1,2-dihydro-3h-pyrazol-3-one, SMR001233303, SBI-0207052.P001, LS-128895, AB00513898, FT-0668467, AB00513898_06, AB00513898_07, I05-2875, J-014886, SR-01000838884-2, SR-01000838884-3, BRD-A08255417-001-03-0, BRD-A08255417-001-06-3, Antipyrine, 4-isopropyl-3-(.alpha.-(methyl-(1-phenyl-2-propyl)amino))-, 3-(N,.alpha.-Dimethylphenethylaminomethyl)-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-one, 3-(N-Methyl-(.alpha.-methyl-.beta.-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine, 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one, 4-Isopropyl-2-methyl-3-([methyl(.alpha.-methylphenethyl)amino]methyl)-1-phenyl-3-pyrazolin-5-one, 4-isopropyl-2-methyl-3-(N-methyl-N-(alpha-methylphenylethyl)aminomethyl)-1-phenyl-3-pyrazolin-5-one, 4-Isopropyl-2-methyl-3-[[methyl(|A-methylphenethyl)amino]methyl]-1-phenyl-3-pyrazolin-5-one

ID: 746

InChIKey: GNWUOVJNSFPWDD-XMZRARIVSA-M
SMILES: CO[C@@]1([C@@H]2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)[O-])NC(=O)CC3=CC=CS3.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441392
synonyms found at PubChem are:
CEFOXITIN SODIUM, Cefoxitin sodium salt, 33564-30-6, Cenomycin, Betacef, Merxin, Cefoxitin (sodium), Monosodium cefoxitin, Mefoxin, Mefoxitin, Mefoxithin, Farmoxin, UNII-Q68050H03T, Cefoxil, Cefoxotin sodium, MLS000028557, CHEBI:3501, Q68050H03T, SMR000058809, Mefoxin (TN), MEFOXIN IN PLASTIC CONTAINER, EINECS 251-574-6, Cefoxitin sodium (JAN/USP), MK 206, (6R,7S)-3-[[(Aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt, CPD000058809, Sodium (6R-cis)-3-((carbamoyloxy)methyl)-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, MEFOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER, NCGC00183034-01, L 620388, MEFOXIN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER, Serviflox, C16H16N3NaO7S2, Cefaxilin Sodium, Prestwick_12, Sodium (6R,7S)-3-(hydroxymethyl)-7-methoxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate carbamate (ester), CAS-33564-30-6, Cefoxitin sodium [USAN:USP:BAN:JAN], Cefoxitin and dextrose in duplex container, Opera_ID_912, CFX, sodium;(6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, DSSTox_CID_28921, DSSTox_RID_83187, DSSTox_GSID_48995, SCHEMBL41178, MLS001076334, MLS002222151, BIDD:GT0505, SPECTRUM1502031, CHEMBL1200530, DTXSID8048995, CTK8F8533, HMS501M18, GNWUOVJNSFPWDD-XMZRARIVSA-M, MolPort-003-666-398, HMS1570H05, HMS1921F14, HMS2092P11, HMS2097H05, HMS2232E15, HMS3259K10, HMS3714H05, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)-, monosodium salt, (6R-cis)-, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)-, sodium salt, (6R-cis)-, BCP12069, HY-B1117, Tox21_113485, 35607-66-0 (acid), CCG-39693, MK 306, AKOS024464829, AC-1303, CS-4716, NC00556, AN-15062, BC202499, O877, SAM002564251, SAM002703131, AB1009432, FT-0603033, C08106, D00913, Cefoxitin sodium salt, Antibiotic for Culture Media Use Only, sodium (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, sodium (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, AKOS015951242

ID: 747

InChIKey: GNXFOGHNGIVQEH-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1OCC(COC(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4107
synonyms found at PubChem are:
methocarbamol, 532-03-6, Robaxin, Metocarbamol, Metocarbamolo, Lumirelax, Parabaxin, Etroflex, Methocal, Metofenia, Miolaxene, Miorilas, Myolaxene, Neuraxin, Reflexyn, Relestrid, Romethocarb, Surquetil, Tresortil, Avetil, Delaxin, Miowas, Perilax, Robinax, Metofenina, Guaiacol glyceryl ether carbamate, Guaiphenesin carbamate, Guaiphenesine carbamate, Glycerylguaiacolate carbamate, Glycerylguajacol-carbamat, Methocarbamolum, Forbaxin, 2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate, AHR 85, Robamol, Robaxan, Robaxine, Robaxon, Traumacut, Guiacol-gliceriletere monocarbammato, Metocarbamolo [DCIT], Robaxisol, 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-carbamate, 3-(2-Methoxyphenoxy)-1-glyceryl carbamate, ROBAXIN-750, Metocarbamol [INN-Spanish], Methocarbamolum [INN-Latin], 3-(o-Methoxyphenoxy)-2-hydroxypropyl carbamate, NSC 170960, 2-Hydroxy-3-(o-methoxyphenoxy)propyl 1-carbamate, 3-(o-Methoxyphenoxy)-1,2-propanediol 1-carbamate, C11H15NO5, HSDB 3122, Methocarbamol (Robaxin), EINECS 208-524-3, BRN 1884446, 1,2-Propanediol, 3-(o-methoxyphenoxy)-, 1-carbamate, MLS000028610, Carbamic acid, 2-hydroxy-3-(o-methoxyphenoxy)propyl ester, CHEBI:77498, [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate, SMR000058719, DSSTox_CID_3286, DSSTox_RID_76958, 1-carbamoyloxy-3-(2'-methoxyphenoxy)-2-propanol, DSSTox_GSID_23286, (+-)-3-(o-Methoxyphenoxy)-1,2-propanediol 1-carbamate, guaiamar carbamate, 2-hydroxy-3-(2-methoxyphenoxy)propyl aminooate, SR-01000000240, 2-hydroxy-3-{[2-(methyloxy)phenyl]oxy}propyl carbamate, Methacarbamol, Methocarbamo, Methocarbamol [INN:BAN:JAN], rac-methocarbamol, NCGC00016492-01, Methocarbamol,(S), CAS-532-03-6, Methocarbamol [USP:INN:BAN:JAN], Prestwick_614, Delaxin (TN), Robaxin (TN), Robaxisol (Salt/Mix), PubChem20751, Spectrum_000997, AC1L1HFD, Opera_ID_1471, Prestwick0_000184, Prestwick1_000184, Prestwick2_000184, Prestwick3_000184, Spectrum2_001272, Spectrum3_000496, Spectrum4_000049, Spectrum5_000956, D0FN7J, 2-Hydroxy-3-(o-methoxyphenoxy)propyl carbamate, SCHEMBL34365, BSPBio_000107, BSPBio_001991, KBioGR_000517, KBioSS_001477, MLS001148605, DivK1c_000434, SPECTRUM1500397, WLN: ZVO1YQ1OR BO1, SPBio_001264, SPBio_002028, BPBio1_000119, GTPL6829, Methocarbamol (JAN/USP/INN), CHEMBL1201117, DTXSID6023286, CTK8B3542, HMS501F16, KBio1_000434, KBio2_001477, KBio2_004045, KBio2_006613, KBio3_001491, KS-00000GJG, GNXFOGHNGIVQEH-UHFFFAOYSA-N, MolPort-003-666-229, NINDS_000434, HMS1568F09, HMS1920L19, HMS2091D14, HMS2095F09, HMS2233G18, HMS3259M17, HMS3369B17, HMS3655O06, HMS3712F09, Pharmakon1600-01500397, BCP13801, HY-B0262, Tox21_110454, ANW-42701, CCG-39655, MFCD00057662, NSC170960, NSC757112, s1736, SBB056990, AKOS015960743, Tox21_110454_1, API0003331, CS-2248, DB00423, MCULE-7298838587, NC00509, NE28012, NSC-170960, NSC-757112, RL03963, IDI1_000434, NCGC00018257-02, NCGC00018257-03, NCGC00018257-04, NCGC00018257-07, NCGC00018257-08, NCGC00089805-02, NCGC00089805-03, 1, 3-(o-methoxyphenoxy)-, 1-carbamate, AC-12037, AN-23552, AS-11691, BC203907, CPD000058719, SAM002554900, SC-13605, 1, 3-(2-methoxyphenoxy)-, 1-carbamate, ACM1189699704, SBI-0051442.P003, AB2000260, LS-120555, 3-O-(2-Methoxyphenyl)-1-glyceryl carbamate, AB00052040, FT-0628302, M2254, ST50993887, D00402, EN300-119525, AB00052040-15, AB00052040_16, AB00052040_17, 2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate #, A829442, [3-(2-methoxyphenoxy)-2-oxidanyl-propyl] carbamate, SR-01000000240-2, SR-01000000240-3, (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate, 1,2-Propanediol,3-(2-methoxyphenoxy)-, 1-carbamate, BRD-A31521121-001-05-8, Guaiacol glyceryl ether carbamate, analytical standard, (+/-)-3-( o-Methoxyphenoxy)-1,2-propanediol 1-carbamate, carbamic acid [2-hydroxy-3-(2-methoxyphenoxy)propyl] ester, Carbamic Acid 2-Hydroxy-3-(2-methoxyphenoxy)propyl Ester, carbamic acid [2-hydroxy-3-(2-methoxy-phenoxy)-propyl] ester, Methocarbamol, United States Pharmacopeia (USP) Reference Standard, Methocarbamol, Pharmaceutical Secondary Standard; Certified Reference Material, 145308-03-8, 3967-43-9

ID: 748

InChIKey: GODATXYKWYGJRN-FTUKGHNWSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C=C[C@H](C2(C)C)OC(=O)C)(C3[C@]1(C4=CC(=O)O[C@@H]([C@]4(CC3)C)C5=COC=C5)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 73357344
synonyms found at PubChem are:
DEOXYGEDUNOL ACETATE, CHEMBL3039133

ID: 749

InChIKey: GOYZKWCPWBKPIG-RNKBQGBYSA-N
SMILES: C[C@@]12CCC3C(=C)[C@]1(CC(=O)O[C@H]2C4=COC=C4)O[C@@H]5[C@]3([C@H](C(C(=O)C5)(C)C)C(C(=O)OC)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708540
synonyms found at PubChem are:
6-HYDROXYANGOLENSIC ACID METHYL ESTER, KBio1_001121, Spectrum_000562, SpecPlus_000081, Spectrum2_000241, Spectrum3_000021, Spectrum4_001301, Spectrum5_000081, BSPBio_001681, KBioGR_001701, KBioSS_001042, SPECTRUM100058, DivK1c_006177, SPBio_000022, CHEMBL1170898, SCHEMBL12998443, KBio2_001042, KBio2_003610, KBio2_006178, KBio3_000801, CCG-39802, SDCCGMLS-0066344.P001, NCGC00179093-01, SR-05000002721, SR-05000002721-1, BRD-A15454510-001-02-8, BRD-A15454510-001-03-6

ID: 750

InChIKey: GPLGAQQQNWMVMM-MYAJQUOBSA-N
SMILES: C[C@H]1[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)N(C)C)C)CN1C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441082
synonyms found at PubChem are:
conessine, Roquessine, Neriine, 546-06-5, Conessinum, Wrightine, Conessin, UNII-EZ38J9BBDF, NSC 119994, EZ38J9BBDF, Konessin, CHEBI:27965, GPLGAQQQNWMVMM-MYAJQUOBSA-N, Conessine [INN], N,N-dimethylcon-5-enin-3beta-amine, ST066907, Conesina [INN-Spanish], Conessinum [INN-Latin], DSSTox_CID_26000, DSSTox_RID_81281, DSSTox_GSID_46000, 3beta-(Dimethylamino)con-5-ene, Conesina, EINECS 208-897-2, BRN 4702160, Con-5-enine, 3.beta.-(dimethylamino)-, ((2S,5S,12S,16S,1R,9R,13R)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0<2,9>.0<5, 9>.0<13,18>]icos-18-en-16-yl)dimethylamine, (3-beta)-N,N-Dimethylcon-5-enin-3-amine, 3beta-(Dimethylamino)con-5-enine, NCGC00095844-01, CAS-546-06-5, Prestwick_692, AC1L9AIB, Prestwick0_000638, Prestwick1_000638, Prestwick2_000638, Prestwick3_000638, D0M9IC, BSPBio_000636, BIDD:ER0525, SCHEMBL791146, SPBio_002855, BPBio1_000700, CHEMBL191703, GTPL8981, Conessine, >=97% (HPLC), DTXSID6046000, BDBM27193, MolPort-004-955-852, HMS1569P18, HMS2096P18, N,N-Dimethyl-con-5-enin-3-amine, ZINC4097188, Tox21_111531, MFCD00016752, SBB012585, AKOS024283367, Tox21_111531_1, NCGC00092388-01, NCGC00092388-03, NCGC00092388-05, (3|A)-N,N-dimethyl-con-5-enin-3-amine, (3beta)-N,N-dimethyl-con-5-enin-3-amine, B7044, Conkurchine, N,18-dihydrotrimethyl- (7CI), Con-5-enine, 3beta-(dimethylamino)- (8CI), C06545, A1-00780, Con-5-enin-3-amine, N,N-dimethyl-, (3beta)- (9CI), (1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-amine

ID: 751

InChIKey: GPTONYMQFTZPKC-UHFFFAOYSA-N
SMILES: COC1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5326
synonyms found at PubChem are:
sulfameter, 651-06-9, 5-Methoxysulfadiazine, Sulfamethoxydiazine, Sulfamethoxine, Sulfametin, Sulphamethoxydiazine, Sulfametoxydiazine, Sulfamethoxypyrimidine, Sulfametorine, Sulphameter, Methoxypyrimal, Sulfamethoxydin, Berlicid, 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide, Sulla, Ultrax, Sulfamethorine, Longasulf, Supramid, Bayrena, Dairena, Durenat, Juvoxin, Kinecid, Kirocid, Kiron, Sulfa-5-methoxypyrimidine, Solfametossidiazina, Sulfametoxipirimidine, Sulfametinum, AHR-857, 2-Sulfanilamido-5-methoxypyrimidine, 5-Methoxy-2-sulfanilamidopyrimidine, Sulfametoxidiazina, Bayer 5400, Sulfametoxydiazinum, 4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide, Sulfameter [USAN], Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyrimidinyl)-, 2-(4-Aminobenzenesulfonamido)-5-methoxypyrimidine, Sulfamethoxydiazin, 2-Sulfanilamido-5-methoxypyrimidin, sulfamethoxidiazine, Solfametossidiazina [DCIT], SH 613, NSC 683528, Sulfameter (Bayrena), Sulfametoxydiazinum [INN-Latin], UNII-3L179F09D6, Sulfametoxidiazina [INN-Spanish], EINECS 211-480-8, I-2586, N(sup 1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide, BRN 0621130, N1-(5-Methoxy-2-pyrimidinyl)sulfanilamide, 2-Sulfanilamido-5-methoxypyrimidin [German], CHEBI:53727, Sulfameter (USAN), NSC683528, Sulfanilamide, N(sup 1)-(5-methoxy-2-pyrimidinyl)-, 3L179F09D6, NCGC00016530-01, CAS-651-06-9, Sulfametoxydiazine (INN), Sulfametoxydiazine [INN], DSSTox_CID_3613, N(1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide, DSSTox_RID_77110, DSSTox_GSID_23613, W-104807, 4-amino-N-(5-methoxypyrimidin-2-yl)benzene-1-sulfonamide, Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyridimidinyl)-, SR-01000721917, [(4-aminophenyl)sulfonyl](5-methoxypyrimidin-2-yl)amine, Sulfametorin, Sulfametorinum, Sulfametoxidine, Sulfamethoxydine, Sulfameter(Bayrena), Prestwick_1048, Sulfameter(Bayrena)/, Sulla (TN), Spectrum_001149, Prestwick0_000769, Prestwick1_000769, Prestwick2_000769, Prestwick3_000769, Spectrum2_001428, Spectrum3_001463, Spectrum4_000426, Spectrum5_000981, D07SYJ, AC1L1K3T, AC1Q4F5G, 2-Sulfa-5-methoxypyrimidine, Oprea1_482593, SCHEMBL79417, BSPBio_000818, BSPBio_002985, KBioGR_000752, KBioSS_001629, 5-25-12-00525 (Beilstein Handbook Reference), MLS000069640, BIDD:GT0693, DivK1c_000468, SPECTRUM1501155, SPBio_001536, SPBio_002757, BPBio1_000900, CHEMBL1200359, DTXSID5023613, GPTONYMQFTZPKC-UHFFFAOYSA-, HMS501H10, KBio1_000468, KBio2_001629, KBio2_004197, KBio2_006765, KBio3_002485, KS-00000GAF, ZINC49142, GPTONYMQFTZPKC-UHFFFAOYSA-N, MolPort-001-838-192, NINDS_000468, HMS1570I20, HMS1921L15, HMS2092J03, HMS2097I20, HMS2233B12, HMS3374J11, HMS3655A11, HMS3714I20, Pharmakon1600-01501155, Sulphanilamide p-methoxy pyrimidine, HY-B0213, Tox21_110478, ABP000630, CCG-38965, MFCD00006067, NSC757874, s1618, SBB057653, AKOS015897255, Tox21_110478_1, API0004272, CS-2158, MCULE-7934329522, NSC-683528, NSC-757874, IDI1_000468, NCGC00016530-02, NCGC00016530-03, NCGC00016530-04, NCGC00016530-06, NCGC00016530-07, NCGC00094915-01, NCGC00094915-02, AC-19932, AJ-09071, AK126667, AN-47084, AS-13912, CC-21973, K058, SC-13276, SMR000058215, ST007538, ZB001465, N1-(5-Methoxypyrimidin-2-yl)sulfanilamide, SBI-0051665.P002, AB0007999, AB2000165, AX8013105, LS-147812, AB00052227, FT-0632748, ST51006758, 51S069, D02517, Sulfameter, VETRANAL(TM), analytical standard, AB00052227-11, AB00052227_12, AB00052227_13, A834976, C-17636, SR-01000721917-2, SR-01000721917-3, BRD-K87492696-001-05-8, BRD-K87492696-001-09-0, 4-azanyl-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide, Z1522567176, 4-amino-N-[5-(methyloxy)pyrimidin-2-yl]benzenesulfonamide, Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyridimidinyl)- (9CI), InChI=1/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

ID: 752

InChIKey: GPTXWRGISTZRIO-UHFFFAOYSA-N
SMILES: CC1=NC2=C(C=C1)C(=CC(=C2O)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6301
synonyms found at PubChem are:
Chlorquinaldol, 72-80-0, 5,7-Dichloro-8-hydroxyquinaldine, Chloroquinaldol, 5,7-dichloro-2-methylquinolin-8-ol, Clorquinaldol, Sterosan, 5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-quinaldinol, Chlorchinaldol, Siasteran, Siosteran, Steroxin, Siogene, Chlorchinaldolum, Chlorquinaldolum, Gyno-sterosan, Clorchinaldolo, Hydroxydichloroquinaldine, 8-QUINOLINOL, 5,7-DICHLORO-2-METHYL-, 5,7-Dichloro-8-hydroxy-2-methylquinoline, Chloquinan, Chlorchinaldin, Chlorguinaldon, Clorchinaldolo [DCIT], Siogen, 5,7-Dichloro-2-methyl-quinolin-8-ol, UNII-D6VHC87LLS, 5,7-Dichloro-2-methyl-8-hydroxyquinoline, C10H7Cl2NO, Clorquinaldol [INN-Spanish], Chlorquinaldolum [INN-Latin], Chlorquinaldol [INN:BAN:DCF], EINECS 200-789-3, D6VHC87LLS, BRN 0156683, MLS002695929, CHEBI:74500, GPTXWRGISTZRIO-UHFFFAOYSA-N, NCGC00095795-04, SMR001549973, 5,7-bis(chloranyl)-2-methyl-quinolin-8-ol, DSSTox_CID_28924, DSSTox_RID_83190, DSSTox_GSID_48998, Chlorchinaldine, CHLORQUINALDOL, Chlorquinaldol (5,7-Dichloro-2-methyl-8-quinolinol), CAS-72-80-0, Gynotherax, Vagisteran, Florabina, Saprosan, Siogenal, Siogeno, Siogenon, Siosept, Sterozan, Quesil, PubChem7553, Chlorquinaldol (INN), 5,7-Dichloro-2-me, Hydroxydichloroquinaldinol, Spectrum2_000524, Spectrum3_001092, Spectrum4_001263, AC1Q2P6V, cid_6301, Oprea1_721210, BSPBio_002764, KBioGR_001846, SPECTRUM212151, 5-21-03-00346 (Beilstein Handbook Reference), SCHEMBL301405, SPBio_000507, AC1L1M83, CHEMBL224325, DTXSID3048998, BDBM76302, KBio3_001984, KS-00000XNR, MolPort-001-770-140, HMS3089A18, HMS3264I07, HMS3652H09, Pharmakon1600-00212151, ZINC119403, BCP11865, HY-B1360, Tox21_113490, CCG-39580, MFCD00023984, NSC755830, s4192, SBB037925, STL502989, AKOS000119838, Tox21_113490_1, 8-Quinolinol,5,7-dichloro-2-methyl-, AN-1262, CS-4899, MCULE-9796243224, NSC-755830, PS-7753, RP27735, NCGC00095795-01, NCGC00095795-02, NCGC00095795-03, NCGC00095795-06, AC-29743, BC215775, KB-86974, Quinolin-8-ol, 5,7-dichloro-2-methyl-, SC-06541, ST085312, ZB003961, 2-methyl-5,7-dichloro-8-hydroxyquinoline, SBI-0207012.P001, LS-142535, TC-071397, TL8005075, FT-0623717, D07208, J10451, M-1867, 5,7-Dichloro-8-hydroxy-2-methylquinoline, 98%, AB00443827_06, AB00443827_07, A837624, SR-01000872737, SR-01000872737-1, W-104478, Z118257784

ID: 753

InChIKey: GQJUGJHJUZSJLZ-UHFFFAOYSA-N
SMILES: CCN1C2=NC=C(C(=C2C=N1)NN=C(C)C)C(=O)OCC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 37274
synonyms found at PubChem are:
Etazolate hydrochloride, Etazolate HCl, 35838-58-5, UNII-7YO3254Y6B, SQ 20009, Etazolate hydrochloride [USAN], 7YO3254Y6B, IN1483, NCGC00093857-01, DSSTox_CID_25767, DSSTox_RID_81109, DSSTox_GSID_45767, Etazolate hydrochloride (USAN), 1-Ethyl-4-[(1-methylethylidene)hydrazino]1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester hydrochloride, ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate hydrochloride, Ethyl 1-ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo(3,4-b)pyridine-5-carboxylate monohydrochloride, CAS-35838-58-5, NSC163611, SR-01000076243, SQ 20,009, Ethyl 1-ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate monohydrochloride, NSC 163611, Etazolate.Hydrochloride, AC1L1XER, 1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester, monohydrochloride, Etazolate hydrochloride, solid, SCHEMBL123105, CHEMBL1256671, DTXSID4045767, CTK8F9510, MolPort-003-666-862, Tox21_111226, Tox21_500440, BS0076, MFCD00209848, AKOS024458128, Tox21_111226_1, API0008346, CCG-221744, Etazolate, Hydrochloride and SQ20009, LP00440, NSC-163611, ACM35838585, NCGC00015403-05, NCGC00261125-01, SO-20009, B6304, EU-0100440, D02655, E 1896, M01713, A828403, SR-01000076243-1, SR-01000076243-3, 1H-Pyrazolo[3, 1-ethyl-4-[(1-methylethylidene)hydrazino]-, ethyl ester, monohydrochloride, 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester hydrochloride, 1-Ethyl-4-[(1-methylethylidene)hydrazino]-1H-pyrazolo-[3,4-b]-pyridine-5-carboxylic acid, ethyl ester hydrochloride, ethyl 1-ethyl-4-(2-(propan-2-ylidene)hydrazinyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate hydrochloride, SQ 20,009; 1-Ethyl-4-[(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester hydrochloride, SCHEMBL16702579

ID: 754

InChIKey: GQWNECFJGBQMBO-UHFFFAOYSA-N
SMILES: CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 27421
synonyms found at PubChem are:
Moban, EN 1733 A, 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one monohydrochloride, 3-Ethyl-6,7-dihydro-2-methyl-5-morpholinomethylindol-4(5H)-one hydrochloride, 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, monohydrochloride, AC1L1D6M, C16H24N2O2.HCl, Molindone hydrochloride [USAN], AKOS026749933, LS-83892, 3-ethyl-2-methyl-5-(morpholin-4-ium-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one chloride, Molindone hydrochloride, 15622-65-8, Molindone HCl, Lidone, Molindone (hydrochloride), EN-1733A, EN300-51039, Moban (TN), 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride, DSSTox_CID_25417, DSSTox_RID_80866, Indol-4(5H)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-, monohydrochloride, DSSTox_GSID_45417, 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-4,5,6,7-tetrahydro-1H-indol-4-one hydrochloride, SMR000499578, Lindone, Molindone hydrochloride [USAN:USP], NCGC00016717-01, AC1Q39NF, CAS-15622-65-8, SCHEMBL41018, C16H25N2O2Cl, MLS001076677, MLS001333061, MLS001333062, MLS002222311, Molindone hydrochloride (USP), CHEBI:6966, CHEMBL1200419, DTXSID5045417, CTK6D0630, 7416-34-4 (Parent), AOB5379, SPN-810, MolPort-006-395-239, HMS1571O11, BCP09555, EN 1733A, HY-B1017, Tox21_110579, Tox21_500665, MFCD01718304, AKOS025401596, Tox21_110579_1, API0004721, CCG-213599, CS-4531, LP00665, NC00658, NCGC00094027-01, NCGC00162218-05, NCGC00261350-01, AC-22611, AS-13875, CPD000499578, SAM002548933, EU-0100665, FT-0672453, M2252, V1985, D00796, Molindone hydrochloride, >=98% (HPLC), solid, SR-01000765437, J-009287, SR-01000765437-3, Molindone hydrochloride, United States Pharmacopeia (USP) Reference Standard, 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-oneHydrochloride, 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-1H-indol-4(5H)-one Hydrochloride, 3-Ethyl-2-Methyl-5-(4-Morpholin-4-Iumylmethyl)-1,5,6,7-Tetrahydroindol-4-One Chloride; 3-Ethyl-6,7-Dihydro-2-Methyl-5-(Morpholinomethyl)Indol-4(5H)-One Monohydrochloride; 3-Ethyl-6,7-Dihydro-2-Methyl-5-Morpholinomethylindol-4(5H)-One Hydrochloride;3-Ethyl, 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1)

ID: 755

InChIKey: GRIXGZQULWMCLU-HUTAOCTPSA-L
SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)[O-])OC)OC2)C(=O)[O-].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441242
synonyms found at PubChem are:
MOXALACTAM DISODIUM, Moxam, latamoxef sodium, Antibiotic 6059-S, Shiomarin, Moxalactam disodium salt, Shionogi 6059S, 64953-12-4, Disodium latamoxef, 6059-S, LY-127935, DSSTox_CID_25595, DSSTox_RID_80988, DSSTox_GSID_45595, LY 127935, EINECS 265-288-4, 6059S, Moxalactam disodium (USAN), S-6059, Moxalactam disodium [USAN:USP], Prestwick_33, Shiomarin (TN), NCGC00017130-01, N-((6R,7R)-2-Carboxy-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4.2.0)oct-2-en-7-yl)-2-(p-hydroxyphenyl)malonamic acid disodium salt, CAS-64953-12-4, Moxam (TN), Latamoxef sodium (JP17), D04VXN, AC1L9AT9, SCHEMBL49015, SPECTRUM1500418, CHEMBL1200357, DTXSID0045595, HMS502N11, HMS1570D19, HMS1920P05, HMS2091H04, 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, disodium salt, 7-[[Carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.o]oct-2-ene-2-carboxylic acid, disodium salt, Disodium 7-((carboxylato(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, Tox21_110793, CCG-40101, AKOS025310623, Tox21_110793_1, API0003434, NCGC00178851-03, D02198, disodium (6R,7R)-7-[[2-(4-hydroxyphenyl)-3-oxido-3-oxopropanoyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, disodium (6R,7R)-7-[2-carboxylato-2-(4-hydroxyphenyl)acetamido]-7-methoxy-3-{[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

ID: 756

InChIKey: GRRIYLZJLGTQJX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 13085
synonyms found at PubChem are:
Dibenzoylhydrazine, N,N'-Dibenzoylhydrazine, 787-84-8, N'-Benzoylbenzohydrazide, 1,2-Dibenzoylhydrazine, Benzoic acid, 2-benzoylhydrazide, N2-Benzoylbenzoic acid hydrazide, HYDRAZINE, 1,2-DIBENZOYL-, N,N-dibenzoylhydrazine, NN'-Dibenzoylhydrazine, C6H5-CO-NH-NH-CO-C6H5, NSC 2762, EINECS 212-329-9, BRN 0523810, AI3-16232, CHEMBL115405, Benzoic acid,2-benzoylhydrazide, CHEBI:38453, N'-(phenylcarbonyl)benzohydrazide, GRRIYLZJLGTQJX-UHFFFAOYSA-N, FR-0116, phenyl-N-(phenylcarbonylamino)carboxamide, PhCOOH azine de, Benzoic acid, azine, sym-Dibenzoylhydrazine, Hydrazine,2-dibenzoyl-, ACMC-209pfb, N''-benzoylbenzohydrazide, N'-benzoyl-benzohydrazide, N,N''-dibenzoylhydrazine, N'-(benzoyl)benzohydrazide, N'-Benzoylbenzohydrazide #, AC1Q5Q6H, ghl.PD_Mitscher_leg0.908, 4-09-00-00935 (Beilstein Handbook Reference), SCHEMBL400890, DTXSID7061142, CTK5E6105, NSC2762, MolPort-000-649-525, Benzoic Acid N'-Benzoyl-Hydrazide, AC1L2106, NSC-2762, ZINC6568023, ANW-37221, BDBM50056896, SBB069503, STK993801, AKOS002311362, MCULE-3930909407, CC-31766, LS-76714, OR315363, ST001541, KB-104255, TR-025155, D0150, FT-0629437, A839496, C-33749, S14-0969, F1048-2711, (NZ,Z)-N-[hydroxy(phenyl)methylene]benzenecarbohydrazonic acid

ID: 757

InChIKey: GSAOUZGPXSGVRS-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=CC(=C(C=C3O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5353357
synonyms found at PubChem are:
6,7-dihydroxyflavone, 38183-04-9, 6,7-dihydroxy-2-phenyl-4H-chromen-4-one, 6,7-Dihydroxy-2-phenyl-chromen-4-one, 6,7-dihydroxy flavone, 4H-1-Benzopyran-4-one, 6,7-dihydroxy-2-phenyl-, CHEMBL300814, 6,7-dihydroxy-2-phenylchromen-4-one, SR-05000002250, PubChem9843, 6,7 - Dihydroxyflavone, D05HBF, AC1NS43N, DivK1c_000421, SCHEMBL980197, SPECTRUM1500718, CTK4H9455, HMS501F03, KBio1_000421, DTXSID60191569, GSAOUZGPXSGVRS-UHFFFAOYSA-N, NINDS_000421, ZINC3871176, BDBM50077318, AKOS024283483, CCG-208431, MCULE-6698063887, ACM38183049, IDI1_000421, NCGC00096018-01, NCGC00096018-02, DA-06282, ST069294, 6,7-bis(oxidanyl)-2-phenyl-chromen-4-one, 6,7-dihydroxy-2-phenyl-1-benzopyran-4-one, FT-0729797, 4H-1-Benzopyran-4-one,6,7-dihydroxy-2-phenyl-, A824040, C-57554, SR-05000002250-2, SR-05000002250-3

ID: 758

InChIKey: GSCPDZHWVNUUFI-UHFFFAOYSA-N
SMILES: C1=CC(=CC(=C1)N)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1645
synonyms found at PubChem are:
3-aminobenzamide, 3544-24-9, m-Aminobenzamide, Benzamide, 3-amino-, INO-1001, 3-Amino-benzamide, Benzamide, m-amino-, meta-aminobenzamide, 3-ABA, 3-Aminobenzimide, 3-amino benzamide, aniline-3-carboxamide, 3-aminobenzoic acid amide, UNII-8J365YF1YH, CCRIS 3925, EINECS 222-586-9, NSC 36962, BRN 2802373, 3-H2NC6H4CONH2, PARP Inhibitor I, 3-ABA, CHEMBL81977, 3-AB, 8J365YF1YH, CHEBI:64042, GSCPDZHWVNUUFI-UHFFFAOYSA-N, SR-01000075657, HSDB 7581, 3-azanylbenzamide, m-amino benzamide, 3-Aminobenzaminde, 4pml, INO1001, 3AB, INO 1001, 3-AB cpd, Spectrum_001492, Tocris-0788, ACMC-209igu, AC1Q4ZAY, AC1Q4ZAZ, Spectrum2_001577, Spectrum3_000972, Spectrum4_001096, Spectrum5_001459, 3-Aminobenzamide, 97%, Lopac-A-0788, D0E7OJ, D0K2PD, UPCMLD-DP128, AC1L1BX0, Lopac0_000043, Oprea1_589004, SCHEMBL16070, BSPBio_001432, BSPBio_002603, KBioGR_000152, KBioGR_001512, KBioGR_002355, KBioSS_000152, KBioSS_001972, KBioSS_002358, 4-14-00-01094 (Beilstein Handbook Reference), MLS002153497, 3-NH2-C6H4CONH2, DivK1c_000717, INO-1001,3-Aminobenzamide, INO-1001/3-Aminobenzamide, SPBio_001514, Benzamide, 3-amino- (9CI), ARONIS015032, UPCMLD-DP128:001, 3-ABA; 3-AB, BCBcMAP01_000186, BDBM27506, CTK1C3689, HMS502D19, KBio1_000717, KBio2_000152, KBio2_001972, KBio2_002355, KBio2_002720, KBio2_004540, KBio2_004923, KBio2_005288, KBio2_007108, KBio2_007491, KBio3_000303, KBio3_000304, KBio3_001823, KBio3_002834, KS-00000VUZ, DTXSID90188922, INO-1001 (3-Aminobenzamide), cMAP_000029, MolPort-000-150-925, NINDS_000717, ZERENEX E/1009157, BCPP000203, Bio1_000466, Bio1_000955, Bio1_001444, Bio2_000152, Bio2_000632, HMS1361H14, HMS1791H14, HMS1989H14, HMS3260I07, HMS3266F08, HMS3402H14, HMS3654C08, HMS3656P18, ZINC157165, ACT07905, BCP27669, KS-000045BT, NSC36962, 3-Aminobenzamide, >=99% (TLC), Tox21_500043, ABP000247, ANW-28204, BBL027669, CCG-39623, HSCI1_000265, MFCD00007989, NSC-36962, s1132, SBB028153, STK730785, AKOS000118163, AS05882, BCP9000790, CM13163, CS-0157, LP00043, MCULE-2277005047, RP20270, RTR-014660, TRA0050413, VZ26330, IDI1_000717, IDI1_033902, SMP2_000089, Biochem Biophys Res Commun 225: 826, NCGC00015034-01, NCGC00015034-02, NCGC00015034-03, NCGC00015034-04, NCGC00015034-05, NCGC00015034-06, NCGC00015034-07, NCGC00015034-08, NCGC00024792-01, NCGC00024792-02, NCGC00024792-03, NCGC00024792-04, NCGC00024792-05, NCGC00024792-06, NCGC00260728-01, AC-10266, AJ-14916, AN-16828, AS-17352, CJ-01603, HY-12022, KB-70407, LS-25343, SC-21769, SMR000375902, U693, ZB006582, AB0019404, DB-022254, ST2417476, TR-014660, A0630, BB 0242898, EU-0100043, FT-0615020, ST45051718, EN300-21784, A 0788, M-3383, 54240-EP2281818A1, 54240-EP2308562A2, A822809, I01-3900, J-511678, SR-01000075657-1, SR-01000075657-3, BRD-K08703257-001-01-4, F3377-1722, INO1001, INO-1001, 3544-24-9, Z119992484, InChI=1/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10

ID: 759

InChIKey: GSDSWSVVBLHKDQ-UHFFFAOYSA-N
SMILES: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4583
synonyms found at PubChem are:
ofloxacin, 82419-36-1, Ofloxacine, Floxin, Tarivid, Oxaldin, Ofloxacino, Ofloxacinum, Ocuflox, Oflocet, Visiren, OFLX, Exocin, DL-8280, Hoe-280, Ofloxacina, Floxin otic, Ofloxacin Otic, Ofloxacina [DCIT], Ofloxacine [French], Ofloxacinum [Latin], Exocine, Flobacin, Zanocin, Floxil, Ofloxacino [Spanish], HOE 280, FLOXIN IN DEXTROSE 5%, Marfloxacin, Medofloxine, Bactocin, Danoflox, Effexin, Flodemex, Flotavid, Floxstat, Fugacin, Inoflox, Kinflocin, Kinoxacin, Loxinter, Mergexin, Novecin, Nufafloqo, Occidal, Oflocee, Oflocin, Oflodal, Oflodex, Oflodura, Ofloxin, Onexacin, Pharflox, Puiritol, Qinolon, Quinolon, Quotavil, Taravid, Tariflox, Tructum, Viotisone, Flovid, Floxal, Liflox, Operan, Orocin, Otonil, Praxin, Sinflo, Tabrin, Telbit, Obide, Ofcin, Oflin, Oflox, Qipro, Rilox, DL 8280, Ofus, Uro Tarivid, PT 01, 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, O-Flox, ORF 18489, Floxin (TN), CCRIS 5233, CHEBI:7731, CHEMBL4, Ofloxacin [USAN:BAN:INN:JAN], Ofloxacin, (S)-Isomer, (+/-)-Floxin, ORF-28489, Ru-43280, 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER, BRN 3657947, MLS000028749, (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, WP-0405, SMR000058192, O 8757, DSSTox_CID_21085, DSSTox_RID_79623, DSSTox_GSID_41085, 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid, C18H20FN3O4, (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, OFX, SR-01000076050, LEVOFLOXACIN HCL, gailuoxian, prifloxcin, prifloxin, Monoflocet, ofloxacin;, HSDB 8030, Ofloxacin,(S), Marfloxacin (TN), NCGC00016948-01, (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, XED, Ocuflox (TN), Ofloxacin (Floxin), CAS-82419-36-1, Floxin Otic (TN), Ofloxacin [USAN:USP:INN:BAN:JAN], Spectrum_001186, AC1L1IHM, Opera_ID_1114, Prestwick0_000237, Prestwick1_000237, Prestwick2_000237, Prestwick3_000237, Spectrum2_001464, Spectrum3_001499, Spectrum4_000324, Spectrum5_001063, ACMC-20m40v, D03NHW, Epitope ID:116889, Lopac0_000904, Oprea1_242882, SCHEMBL24373, BSPBio_000313, BSPBio_003117, KBioGR_000667, KBioSS_001666, fluoro-methyl-(4-methylpiperazin-1-yl)-oxo-[?]carboxylic acid, MLS001074203, MLS006011774, DivK1c_000721, SPECTRUM1502044, SPBio_001387, SPBio_002234, Ofloxacin (JP15/USP/INN), Ofloxacin (JP17/USP/INN), BPBio1_000345, DTXSID3041085, SCHEMBL14163982, HMS502E03, KBio1_000721, KBio2_001666, KBio2_004234, KBio2_006802, KBio3_002617, KS-00000UJW, GSDSWSVVBLHKDQ-UHFFFAOYSA-N, MolPort-000-422-241, NINDS_000721, HMS1568P15, HMS1921H12, HMS2090F07, HMS2092B10, HMS2095P15, HMS2235C05, HMS3259G07, HMS3262F10, HMS3369B01, HMS3393K06, HMS3604B17, HMS3712P15, Pharmakon1600-01502044, BCP14346, EBD13209, HY-B0125, RKL10083, 118120-51-7 (hydrochloride), Ofloxacin, fluoroquinolone antibiotic, Tox21_110703, Tox21_500904, BBL005605, BDBM50045004, CCG-39210, MFCD00226105, MFCD00865049, NSC727071, NSC758178, s1463, STK256723, AKOS001033517, AKOS016042783, Ofloxacine; DL-8280; HOE-280, Tox21_110703_1, AC-7616, AN-8832, BCP9000851, CS-1891, DB01165, KS-5011, LP00904, NC00466, NSC-727071, NSC-758178, VA11432, IDI1_000721, NCGC00015772-02, NCGC00015772-03, NCGC00015772-04, NCGC00015772-05, NCGC00015772-06, NCGC00015772-07, NCGC00015772-08, NCGC00015772-09, NCGC00015772-10, NCGC00015772-12, NCGC00015772-13, NCGC00094219-01, NCGC00094219-02, NCGC00094219-03, NCGC00094219-04, NCGC00094219-05, NCGC00094219-06, NCGC00178284-01, NCGC00178284-02, NCGC00261589-01, ( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure, (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure, (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid, 83380-47-6, CPD000058192, H778, SAM002264629, SC-12664, SC-17360, ST073364, SBI-0050879.P003, AB0013254, AB1009384, LS-133259, AB00513820, EU-0100904, FT-0630905, O0403, ST24048838, Ofloxacin, VETRANAL(TM), analytical standard, VU0243192-7, 86O854, C07321, D00453, J10376, O-2800, W-3058, AB00052263-12, AB00052263-13, AB00052263_14, AB00052263_15, Ofloxacin, Antibiotic for Culture Media Use Only, I06-0112, I06-0380, SR-01000076050-1, SR-01000076050-4, SR-01000076050-7, BRD-A24228527-001-05-9, BRD-A24228527-001-19-0, Z56761309, F0020-0095, F0472-0226, 138199-71-0 (0.5H2O), Ofloxacin, European Pharmacopoeia (EP) Reference Standard, Ofloxacin, United States Pharmacopeia (USP) Reference Standard, (+/-)-9-Fluoro-2,2,3-de)-1,4-benzoxazine-6-carboxylic acid, Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material, DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin, ()-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoazine-6-carboxylic acid, (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, (-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure, 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,(1)(3)]trideca-5(13),6,8,11-tetraene-11-carboxylic acid, 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0;{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid, 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, 85344-55-4, 9-Fluoro-10-(4-methylpiperazino)-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzooxazine-6-carboxylic acid, 9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid, 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de]-1,4-Benzoxazin-6-carboxylic Acid, 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid, 9-fluoro-3-methyl-10-(4-methylpiperazino)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, AC1MMN6P, MolPort-000-758-642, STL047996, AKOS005701543, MCULE-5746531107, 9-fluoro-3-methyl-10-(4-methylpiperazin-4-ium-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

ID: 760

InChIKey: GSNOZLZNQMLSKJ-UHFFFAOYSA-N
SMILES: CCN(CC)C1=CC(=NC2=NC=NN12)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5531
synonyms found at PubChem are:
trapidil, Rocornal, Trapymin, 15421-84-8, Avantrin, Trapymine, N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, AR 12008, Trapidilum [INN-Latin], UNII-EYG5Y6355E, EINECS 239-434-2, BRN 0186842, 7-Diethylamino-5-methyl-s-triazolo(1,5-a)pyrimidine, MLS000567667, EYG5Y6355E, N,N-Diethyl-5-methyl-(1,2,4)triazolo(1,5-a)pyrimidine-7-amine, (1,2,4)Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-, 5-Methyl-7-diethylamino-s-triazolo-(1,5-a)-pyrimidine, NCGC00016715-01, AR-12008, s-Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-, SMR000154170, 5-Methyl-7-diaethylamino-s-triazolo(1.5-a)pyrimidin [German], CAS-15421-84-8, DSSTox_CID_25416, DSSTox_RID_80865, DSSTox_GSID_45416, 7-(Diethylamino)-5-methyl-s-triazolo(1,5-a)pyrimidine, Trapidilum, [1,2,4]Triazolo[1,5-a]pyrimidin-7-amine,N,N-diethyl-5-methyl-, [1,2,4]Triazolo[1,5-a]pyrimidin-7-amine, N,N-diethyl-5-methyl-, N,N-Diethyl-4-methyl-1,5,7,9-Tetrazabicyclo[4.3.0]Nona-2,4,6,8-Tetraen-2-Amine, Trapidil [INN:JAN], Trapidil [INN:BAN:JAN], 7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE, Rocornal (TN), Trapidil,(S), Opera_ID_461, AC1L1KJW, AC1Q2YYL, Prestwick0_001012, Prestwick1_001012, Prestwick2_001012, Prestwick3_001012, Trapidil (JP17/INN), D0U2CV, D0X8TP, SCHEMBL33563, BSPBio_001163, MLS000881142, SPBio_003034, 5-Methyl-7-diaethylamino-s-triazolo(1.5-a)pyrimidin, BPBio1_001281, CHEMBL132767, ZINC2202, Trapidil, >=98% (HPLC), DTXSID0045416, CHEBI:32254, CTK4C8160, GSNOZLZNQMLSKJ-UHFFFAOYSA-N, MolPort-001-815-742, HMS1571K05, HMS1735K19, HMS2098K05, HMS2231G07, HMS3372J09, HMS3715K05, BCP09350, HY-B1016, KS-00001FA2, Tox21_110578, MFCD00193104, s4736, AKOS001093408, Tox21_110578_1, CCG-221012, CS-4529, DB09283, HS-0048, MCULE-8684419953, SU10991, NCGC00016715-02, NCGC00016715-04, BC282674, ZB000502, LS-156746, AB00457635, FT-0763046, D01220, AB00457635-12, 421T848, SR-01000673280, SR-01000673280-3, 5-Methyl-7-diethylamino-S-triazolo(1,5-a)pyrimidine, BRD-K95763993-001-03-7, Z56791867, 5-Methyl-7-(diethylamino)-s-triazolo[1,5-a]pyrimidine, 7-(Diethylamino)-5-methyl-2-triazolo[1,5-a]pyrimidine, Trapidil, European Pharmacopoeia (EP) Reference Standard, N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine, N,N-Diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine #, N,N-diethyl-N-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amine

ID: 761

InChIKey: GSQOBTOAOGXIFL-LFIBNONCSA-N
SMILES: C1=CC=C(C=C1)CCCNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5328770
synonyms found at PubChem are:
TYRPHOSTIN AG 555, AG 555, 133550-34-2, MLS000069704, SMR000058519, CHEMBL53898, Tyrphostin B46, AG-555, (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide, (e)-2-cyano-3-(3,4-dihydroxyphenyl)-n-(3-phenylpropyl)acrylamide, (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide, 149092-34-2, SR-01000000219, Tyrphostin B-46, Tocris-0618, Tyrphostin deriv. 46, Opera_ID_732, AC1NS5AX, Lopac-T-4818, N-(3-Phenylpropyl)-3,4-dihydroxy-alpha-cyanocinnamide, Lopac0_001158, MLS001076316, SCHEMBL645290, SCHEMBL645291, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide, BDBM4303, cid_5328770, MolPort-003-983-734, HMS2230N06, BCP25507, EX-A1470, ZINC2557957, BS0024, HSCI1_000030, AKOS016368124, CCG-205232, CS-7554, LP01158, NCGC00016028-01, NCGC00016028-02, NCGC00016028-03, NCGC00016028-04, NCGC00016028-05, NCGC00016028-06, NCGC00016028-07, NCGC00016028-08, NCGC00021314-02, NCGC00021314-04, NCGC00021314-05, HY-15336, B6377, EU-0101158, T 4818, J-006402, SR-01000000219-2, SR-01000000219-4, BRD-K34428485-001-01-0, N-(3-Phenylpropyl)-3,4-dihydroxy-alpha cyanocinnamide, 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)acrylamide, N-(3-Phenylpropyl)-alpha-cyano-3,4-dihydroxy-trans-cinnamamide, (2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-(3-Phenylpropyl)-2-Propenamide, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide, (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)- 2-propenamide, (E)-3-[3,4-bis(oxidanyl)phenyl]-2-cyano-N-(3-phenylpropyl)prop-2-enamide, 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-,(2E)-, Tyrphostin B46, N-(3(c) yen-Phenylpropyl)-3,4-Dihydroxybenzylidenecyanoacetamide, Tyrphostin AG-555,133550-34-2,,Tyrphostin AG 555,Tyrphostin AG-555,Tyrphostin AG555

ID: 762

InChIKey: GSVQIUGOUKJHRC-UHFFFAOYSA-N
SMILES: CC(CN(C1=C(C=C(C(=C1I)N)I)I)C(=O)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 27648
synonyms found at PubChem are:
IOCETAMIC ACID, Cholebrine, Cholimil, Colebrina, Acidum jocetamicum, 16034-77-8, Acide iocetamique [INN-French], Acido iocetamico [INN-Spanish], Acidum iocetamicum [INN-Latin], HSDB 3344, DRC 1201, EINECS 240-173-1, MP 620, MP-620, BRN 2171366, beta-Alanine, N-acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-, N-Acetyl-N-(3-amino-2,4,6-triiodophenl)-2-methyl-beta-alanine, N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-2-methyl-beta-alanine, 3-(Acetyl-(3-amino-2,4,6-triiodophenyl)amino)-2-methylpropanoic acid, N-Acetyl-N-(2,4,6-triiodo-3-aminophenyl)-beta-aminoisobutyric acid, N-Acetyl-N-(3-amino-2,4,6-triiodophenyl)-beta-aminoisobutyric acid, Propanoic acid, 3-(acetyl(3-amino-2,4,6-triiodophenyl)amino)-2-methyl-, Propionic acid, 3-(acetyl-(3-amino-2,4,6-triiodophenyl)amino)-2-methyl-, Acido iocetamico, 3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic acid, 3-[acetyl(3-amino-2,4,6-triiodophenyl)amino]-2-methylpropanoic acid, Acide iocetamique, Acidum iocetamicum, Iocetamic acid [USAN:BAN:INN], Cholebrine (TN), NCGC00016720-01, CAS-16034-77-8, Iocetamic acid [USAN:USP:INN:BAN], Iocetamic acid (USAN), AC1L1DNS, Prestwick0_000838, Prestwick1_000838, Prestwick2_000838, Prestwick3_000838, DSSTox_CID_3149, D0P5CD, DSSTox_RID_76891, DSSTox_GSID_23149, SCHEMBL38499, BSPBio_000795, MLS002154025, SPBio_002716, BPBio1_000875, CHEMBL1200770, DTXSID2023149, CHEBI:91662, HMS1570H17, HMS2097H17, HMS2234P18, HMS3373O18, HMS3714H17, Tox21_110580, AKOS022181574, CCG-220838, NCGC00179430-01, SMR001233352, LS-124477, AB00513935, D04563, SR-01000838894, SR-01000838894-2, BRD-A37492983-001-03-8, 3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic, 3-(N-(3-Amino-2,4,6-triiodophenyl)acetamido)-2-methylpropanoic acid

ID: 763

InChIKey: GSZQTIFGANBTNF-UHFFFAOYSA-N
SMILES: C(CN)CP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 97587
synonyms found at PubChem are:
3-Aminopropylphosphonic acid, 13138-33-5, (3-aminopropyl)phosphonic acid, Aminopropylphosphonate, 3-Aminopropylphosphonicacid, UNII-VM92T06VPB, (3-Amino-propyl)-phosphonic acid, Phosphonic acid, (3-aminopropyl)-, VM92T06VPB, CHEMBL286077, GSZQTIFGANBTNF-UHFFFAOYSA-N, GEO-00218, 3-phosphonopropylamine, NSC-133832, NSC 133832, Phosphate analogue, 8, PubChem10325, ACMC-1BXXY, 3-aminopropyl-phosphonate, AC1L3YTO, timtec-bb sbb004184, Lopac-A-7162, D04LZJ, AC1Q6RQ7, Lopac0_000080, Oprea1_378449, SCHEMBL35883, C3H10NO3P, (3-amino-propyl)phosphonic acid, (3-aminopropyl)-phosphonic acid, CTK4B7246, DTXSID50157018, 3-aminopropylphosphonic acid 97%, MolPort-003-928-865, HMS3260O21, 3-Aminopropylphosphonic acid, 98%, ACT06752, KS-00000NW8, ZX-AT015239, Phosphonic acid,P-(3-aminopropyl)-, Tox21_500080, (3-aminopropyl)phosphonic acid,97%, ANW-51509, BDBM50032981, FCH931628, MFCD00008222, NSC133832, SBB004184, ZINC19737048, AKOS003614667, Phosphonic acid, P-(3-aminopropyl)-, CA-1914, CCG-204175, CM10052, GS-4398, LP00080, LS40178, MCULE-7175026527, OR60033, RP20497, NCGC00015085-01, NCGC00015085-02, NCGC00015085-03, NCGC00015085-04, NCGC00093586-01, NCGC00093586-02, NCGC00260765-01, AJ-74762, AK-33107, BR-33107, CC-14235, KB-29845, SC-00767, ST055646, (3-aminopropyl)phosphonic acid, 97% 1gr, AB0021174, AX8009316, DB-042022, ST2417484, TR-004283, 4CH-001847, AM20080224, BB 0259732, EU-0100080, FT-0636807, V2414, A 7162, S-3558, Phosphonic acid, (3-aminopropyl)- (8CI)(9CI), 138A335, C-01856, L000070, SR-01000075683, I04-1567, J-511723, SR-01000075683-1, (3-aminopropyl)phosphonate, AC1NJ8F7, 3-azaniumylpropyl(hydroxy)phosphinate, CJ-16346

ID: 764

InChIKey: GTACSIONMHMRPD-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)S(=O)(=O)NCCSC2=CC(=C(C(=C2)F)OCC(=O)N)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603828
synonyms found at PubChem are:
PEPA, 141286-78-4, 2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide, 4-(2-(phenylsulfonylamino)ethylthio)-2,6-difluorophenoxyacetamide, 2-[2,6-Difluoro-4-[[2-[(phenylsulfonyl)amino]ethyl]thio]phenoxy]acetamide, 2-[2,6-Difluoro-4-({2-[(Phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, P99, NCGC00015379-01, Lopac-D-8941, AC1O7G2N, Lopac0_000800, SCHEMBL1171583, CHEMBL1097940, CTK8E9461, KS-00001CYW, DTXSID60424960, MolPort-003-941-182, HMS3262O22, BCP16187, ZINC2541692, Tox21_500800, 3963AH, MFCD04974493, AKOS024457340, CCG-204884, CS-3633, LP00800, NCGC00015379-02, NCGC00015379-03, NCGC00015379-04, NCGC00094134-01, NCGC00094134-02, NCGC00261485-01, HY-12509, KB-288630, RT-015006, EU-0100800, D 8941, SR-01000076010, J-007478, SR-01000076010-1, 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoropheno-xyacetamide, 2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acet-amide, 2,6-Difluoro-4-[2-(phenylsul-fonyl-amino)-ethyl-thio]-phenoxy-acetamide, 2-[4-[2-(benzenesulfonamido)ethylsulfanyl]-2,6-difluorophenoxy]acetamide, 2,6-Difluoro-4-[2-(phenylsul??fonyl??amino)??ethyl??thio]??phenoxy??acet??amide, >=98% (HPLC), solid

ID: 765

InChIKey: GTDIWCITYRGAKM-OBRHJWQCSA-N
SMILES: C[C@H]1[C@@H]2CC[C@]3(C=CC(=O)[C@@]4([C@@]3([C@H]2OC1=O)O4)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6481646
synonyms found at PubChem are:
EPOXY (4,5alpha)-4,5-DIHYDROSANTONIN, Santonin alpha-epoxide, Spectrum_001085, Spectrum_001211, SpecPlus_000028, SpecPlus_000483, Spectrum2_000161, Spectrum3_001310, Spectrum4_000895, Spectrum4_001683, Spectrum5_001404, Spectrum5_001666, BSPBio_002979, KBioGR_001330, KBioGR_001946, KBioSS_001565, KBioSS_001691, SPECTRUM211031, DivK1c_006124, DivK1c_006579, SPBio_000021, CHEMBL3039359, KBio1_001068, KBio1_001523, KBio2_001565, KBio2_001691, KBio2_004133, KBio2_004259, KBio2_006701, KBio2_006827, KBio3_002199, CCG-38374, Epoxy(4,5alpha)-4,5-dihydrosantonin, SDCCGMLS-0066547.P001, NCGC00178362-01, SR-05000002512, SR-05000002512-1, BRD-K82229777-001-02-8

ID: 766

InChIKey: GTKXSYHXQSKWNP-UHFFFAOYSA-N
SMILES: C1CCC(CC1)(C(=O)O)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2724466
synonyms found at PubChem are:
39692-17-6, 1-Amino-1-cyclohexanecarboxylic acid hydrochloride, 1-aminocyclohexanecarboxylic acid hydrochloride, 1-Aminocyclohexane-1-carboxylic acid hydrochloride, UNII-0480546720, 1-AMINO-CYCLOHEXANECARBOXYLIC ACID HCL, 1-aminocyclohexanecarboxylic acid, chloride, Homocycloleucine hydrochloride, EINECS 254-594-3, ACMC-20aoyd, 1-Aminocyclohexane-1-carboxylic acid HCl, AC1MC4Z2, 1-AMINO-CYCLOHEXANECARBOXYLIC ACID HYDROCHLORIDE, SCHEMBL1321302, CHEMBL1256358, CTK1C3541, DTXSID30192780, GTKXSYHXQSKWNP-UHFFFAOYSA-N, MolPort-004-946-882, KS-000023VG, ZX-RL004479, Tox21_500117, SBB003752, AKOS015893011, CCG-221421, LP00117, ACM39692176, NCGC00093611-01, NCGC00260802-01, BP-13274, CS-10015, KB-11085, OR300710, 1-Amino-1-cyclohexanecarboxylic acid, HCl, DB-049466, TC-172012, A-162, EU-0100117, FT-0639567, ST50405341, 1-aminocyclohexane-carboxylic acid hydrochloride, C-49905, SR-01000075423, I04-1630, SR-01000075423-1, F0001-1116, 1-Aminocyclohexanecarboxylic acid hydrochloride, AldrichCPR, MolPort-000-720-237, MCULE-1248384499

ID: 767

InChIKey: GTVPOLSIJWJJNY-UHFFFAOYSA-N
SMILES: CN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4592
synonyms found at PubChem are:
olomoucine, 101622-51-9, 4erk, UNII-6A839B2HYS, InSolution™ Olomoucine, 2-(2-Hydroxyethylamino)-6-benzylamino-9-methylpurine, 6A839B2HYS, CHEMBL280074, IN1179, 6-Benzylamino-2-(2-hydroxyethylamino)-9-methylpurine, 6-(Benzylamino)-2-(2-hydroxyethylamino)-9-methylpurine, 2-{[6-(benzylamino)-9-methyl-9h-purin-2-yl]amino}ethanol, Ethanol,2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine, OLO, 6-Benylamino-2-(2-hydroxyethylamino)-9-methylpurine, 6-benzylamino-2-[2-hydroxyethylamino]-9-methylpurine, 2-(2-Hydroxyethylamino)-6-benzylamino-9-isopropylpurine, 2-[[6-(benzylamino)-9-methylpurin-2-yl]amino]ethanol, C15H18N6O, 2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethan-1-ol, SR-01000075518, Olomucine, purine deriv. 5, NSC 666096, NSC-666096, Kinome_2870, Tocris-1284, 1w0x, ACMC-20cp0o, AC1L1IID, AC1Q4XZU, BiomolKI_000046, Lopac-O-0886, BiomolKI2_000052, D00BPA, UPCMLD-DP136, CBiol_002050, Lopac0_000883, BSPBio_000990, KBioGR_000330, KBioSS_000330, SCHEMBL135056, BDBM5718, BMK1-E10, 2-(2-Hydroxyethylamino)-6-(benzylamino)-9-methylpurine, Olomoucine, >=98% (HPLC), UPCMLD-DP136:001, UPCMLD-DP136:002, BCBcMAP01_000205, CTK4A0020, KBio2_000330, KBio2_002898, KBio2_005466, KBio3_000659, KBio3_000660, BIO3107, DTXSID90144068, GTVPOLSIJWJJNY-UHFFFAOYSA-N, MolPort-003-849-700, ZX-AFC001655, Bio1_000336, Bio1_000825, Bio1_001314, Bio2_000335, Bio2_000815, HMS1362B11, HMS1792B11, HMS1990B11, HMS3262B08, HMS3267L09, HMS3403B11, HMS3650F19, ZINC1641925, Tox21_500883, 1966AH, IN1182, MFCD00189360, NSC666096, AKOS005145988, CCG-100650, DB02116, LP00883, TRA0035611, IDI1_002090, SMP1_000281, 2,6,9-Trisubstituted purine deriv. 26, NCGC00015763-01, NCGC00015763-02, NCGC00015763-03, NCGC00015763-04, NCGC00015763-05, NCGC00015763-06, NCGC00015763-07, NCGC00015763-08, NCGC00015763-09, NCGC00025096-01, NCGC00025096-02, NCGC00025096-03, NCGC00025096-04, NCGC00025096-05, NCGC00025096-06, NCGC00025096-07, NCGC00261568-01, CJ-26517, NCI60_022916, KB-162429, RT-014854, EU-0100883, FT-0642456, ST50298830, O 0886, C-28477, J-000453, SR-01000075518-1, SR-01000075518-3, SR-01000075518-6, BRD-K82731415-001-03-9, BRD-K82731415-001-04-7, 2-[[6-(benzylamino)-9-methyl-purin-2-yl]amino]ethanol, 2-({9-methyl-6-[benzylamino]purin-2-yl}amino)ethan-1-ol, 2-(6-(benzylamino)-9-methyl-9H-purin-2-ylamino)ethanol, 6-(benzylamino)-2-[(2-hydroxyethyl)amino]-9-methylpurine, 2-[[9-methyl-6-(phenylmethylamino)purin-2-yl]amino]ethanol, 2-[[9-Methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol, 2-[[9-Methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]ethanol, 2-[[9-Methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]ethanol, 9CI, Ethanol, 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-

ID: 768

InChIKey: GUBNMFJOJGDCEL-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441344
synonyms found at PubChem are:
Dicyclomine hydrochloride, 67-92-5, Dicyclomine Hcl, Antispas, Benacol, Icramin, Spasmoject, Stannitol, Ametil, Dibent, Dicycloverine hydrochloride, UNII-CQ903KQA31, BENTYL PRESERVATIVE FREE, Dicycloverin hydrochloride, EINECS 200-671-1, NSC 404381, AI3-18105, MLS000028426, MLS001074064, CQ903KQA31, 2-Diethylaminoethyl bicyclohexyl-1-carboxylate hydrochloride, SMR000058440, 2-(Diethylamino)ethyl (bicyclohexyl)-1-carboxylate hydrochloride, beta-Diethylaminoethyl-1-cyclohexylhexahydrobenzoate hydrochloride, Bis(cyclohexyl)carboxylic acid diethylaminoethyl ester hydrochloride, beta-Diethylaminoethyl-1-cyclohexylcyclohexanecarboxylate hydrochloride, Bentyl (TN), (1,1'-Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride, 1-Cyclohexyl-cyclohexan-1-carbonsaeure-2-diaethylaminoaethylester hydrochlorid [German], Cloridrato dell'estere beta-dietil aminoetilico dell'acido cicloesil-1-cicloesancarbossilico, [Bicyclohexyl]-1-carboxylic acid diethylaminoethyl ester, beta-Diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate hydrochloride, (2-(((1,1'-Bicyclohexyl)-1-ylcarbonyl)oxy)ethyl)diethylammonium chloride, 2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, CHEBI:4515, (BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE, SR-01000003056, 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate, chloride, Dicyclomine hydrochloride [USP], 2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate;hydrochloride, Dicyclomine hydrochloride [USAN], Dicycloverine HCl, (1,1'-Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride (1:1), [1,1'-Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride (1:1), Prestwick_891, Opera_ID_272, Dicyclomine hydrochloride (preservative-free), AC1L9B0G, C19H35NO2.HCl, SCHEMBL41670, 77-19-0 (Parent), SPECTRUM1500240, CHEMBL1200479, DTXSID0058778, REGID_for_CID_441344, MolPort-003-666-161, HMS1568I17, HMS1920E22, Pharmakon1600-01500240, Tox21_500432, CCG-39149, Dicyclomine hydrochloride (JAN/USP), MFCD00079158, NSC756727, SBB058148, 1-Cyclohexyl-cyclohexan-1-carbonsaeure-2-diaethylaminoaethylester hydrochlorid, AKOS015950777, LP00432, MCULE-7810636561, NC00504, NSC-756727, 67-92-5 (HCl), NCGC00093853-01, NCGC00093853-02, NCGC00093853-03, NCGC00093853-04, NCGC00093853-05, NCGC00261117-01, AN-23770, CPD000058440, LS-43730, LS-56641, SAM002554894, AB1004835, EU-0100432, FT-0624744, ST51014989, D 7909, D00717, 067D925, Dicyclomine hydrochloride, >=99% (TLC), powder, SR-01000003056-2, SR-01000003056-7, 2-(diethylamino)ethyl bi(cyclohexane)-1-carboxylate hydrochloride, 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate hydrochloride, Dicycloverine hydrochloride, European Pharmacopoeia (EP) Reference Standard, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride, Dicyclomine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride; [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride, Dicyclomine HCI, AC1LCWDV, AKOS026750112, 2-Diethylaminoethyl bicyclohexyl-1-carboxylate HCl, 2-diethylaminoethyl 1-cyclohexylcyclohexane-1-carboxylate; hydron; chloride, dicycloverin HCl, 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate hydrochloride, 2-{[1,1'-bi(cyclohexyl)-1-ylcarbonyl]oxy}-N,N-diethylethanaminium chloride

ID: 769

InChIKey: GUGJQAFPKZZOIV-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN=C(N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6917872
synonyms found at PubChem are:
HA-1004 hydrochloride, 92564-34-6, N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide hydrochloride, HA-1004 DIHYDROCHLORIDE, ha-1004, AC1OCER2, HA 1004 Hydrochloride, SCHEMBL1165287, CHEMBL1204354, GUGJQAFPKZZOIV-UHFFFAOYSA-N, MFCD00069285, FT-0629134, HA-1004 hydrochloride, >=98% (HPLC), powder, N-(2-guanidinoethyl)isoquinoline-5-sulfonamide hydrochloride, N-(2-guanidinoethyl)-5-isoquinolinesulfonamide monohydrochloride, 2-[2-(isoquinolin-5-ylsulfonylamino)ethyl]guanidine hydrochloride, N-[2-[(Aminoiminomethyl)amino]ethyl]-5-isoquinolinesulfonamide Monohydrochloride

ID: 770

InChIKey: GUGOEEXESWIERI-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5405
synonyms found at PubChem are:
terfenadine, Seldane, 50679-08-8, Ternadin, Triludan, Teldane, Allerplus, Teldanex, Aldaban, Terdin, Terfenadina, Terfenadinum, Cyater, Terfen, Terfenidine, Terfex, RMI 9918, RMI-9918, Terfenadinum [INN-Latin], Terfenadina [INN-Spanish], MDL 9918, Seldane (TN), C32H41NO2, HSDB 6508, MDL-9918, Terfenadine [USAN:BAN:INN:JAN], EINECS 256-710-8, BRN 5857899, alpha-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, CHEMBL17157, MLS000028499, Terfenadine (JAN/USAN/INN), CHEBI:9453, GUGOEEXESWIERI-UHFFFAOYSA-N, alpha-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, 1-(4-tert-Butylphenyl)-4-(4-(alpha-hydroxybenzhydryl)piperidino)-butan-1-ol, 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol, 1-(p-tert-Butylphenyl)-4-(4'-(alpha-hydroxydiphenylmethyl)-1'-piperidyl)butanol, alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, 1-Piperidinebutanol, .alpha.-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-, 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-, NCGC00016064-04, NCGC00016064-06, SMR000058260, DSSTox_CID_3642, 1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol, T 9652, alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol, DSSTox_RID_77124, DSSTox_GSID_23642, Terfemundin, Hisfedin, Rapidal, Terfedura, Terfenadin AL, Terfenadin Stada, 1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol, terfenadin von ct, Terfenadin Heumann, 1-(4-(tert-Butyl)phenyl)-4-(4-(hydroxydiphenylmethyl)-piperidin-1-yl)butan-1-ol, 1-(4-(tert-butyl)phenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol, 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]butan-1-ol, 1-[4-(1,1-dimethylethyl)phenyl]-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butan-1-ol, alpha-(4-[1,1-Dimethylethyl]phenyl)-4-[hydroxydiphenylmethyl]-1-piperidinebutanol, Balkis Saft Spezial, Terfenadin-ratiopharm, SR-01000000104, teraenadine, UNII-7BA5G9Y06Q, Terfenadin, Terfenadine,(S), RMI9918, racemic terfenadine, (-)-Terfenadine, Triludan (TN), Prestwick_460, Teldane (TN), CAS-50679-08-8, Terfenadine [USAN:USP:INN:BAN:JAN], Opera_ID_334, AC1Q1LZA, Prestwick0_000138, Prestwick1_000138, Prestwick2_000138, Prestwick3_000138, (.+/-.)-Terfenadine, Bial Brand of Terfenadine, Aliud Brand of Terfenadine, D08SOF, Wolff Brand of Terfenadine, AC1L1KA8, SCHEMBL5152, Heumann Brand of Terfenadine, Hoechst Brand of Terfenadine, Lopac0_001213, Oprea1_343139, BSPBio_000216, MLS001148415, DivK1c_001011, Cantabria Brand of Terfenadine, Dolorgiet Brand of Terfenadine, SPBio_002155, ratiopharm Brand of Terfenadine, 7BA5G9Y06Q, BPBio1_000238, GTPL2608, Sigma Tau Brand of Terfenadine, Sigma-Tau Brand of Terfenadine, Stadapharm Brand of Terfenadine, Merck dura Brand of Terfenadine, DTXSID2023642, Mundipharma Brand of Terfenadine, HMS503K03, KBio1_001011, MolPort-002-904-065, NINDS_001011, HMS1568K18, HMS2089I14, HMS2093I11, HMS2095K18, HMS2231N07, HMS3263D08, HMS3373J07, HMS3712K18, Pharmakon1600-01503708, HY-B1193, ct Arzneimittel Brand of Terfenadine, ct-Arzneimittel Brand of Terfenadine, Tox21_110295, Tox21_110296, Tox21_501213, AC-928, BDBM50017376, BG0333, MFCD00079622, NSC665802, NSC758627, AKOS015962091, Tox21_110295_1, API0024492, CCG-205287, CS-4800, DB00342, LP01213, MCULE-8216311776, NSC-665802, NSC-758627, VA11848, ACM50679088, IDI1_001011, NCGC00016064-03, NCGC00016064-05, NCGC00016064-08, NCGC00016064-09, NCGC00016064-12, NCGC00089746-02, NCGC00089746-03, NCGC00089746-04, NCGC00261898-01, AC-15791, AN-41415, CC-34708, NCI60_022784, SBI-0051180.P003, KB-270766, LS-114369, AB00052367, EU-0101213, FT-0630637, ST50307835, BIM-0051180.0001, C07463, D00521, AB00052367-16, AB00052367_17, AB00052367_18, C-22717, L000888, ( inverted exclamation markA)-Terfenadine;MDL-9918, SR-01000000104-2, SR-01000000104-4, SR-01000000104-7, BRD-A06352418-001-03-6, BRD-A06352418-001-15-0, I14-107294, Terfenadine, European Pharmacopoeia (EP) Reference Standard, Terfenadine, United States Pharmacopeia (USP) Reference Standard, .alpha.-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, 1-[4-(tert-butyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidyl]butan-1-ol, (+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol, (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol, .alpha.-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenyl-methyl)-1-piperidine butanol, .alpha.-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, 1-(4-tert-Butyl-phenyl)-4-[4-(hydroxy-diphenyl-methyl)-piperidin-1-yl]-butan-1-ol, 1-(4-tert-Butylphenyl)-4-(4-[hydroxy(diphenyl)methyl]-1-piperidinyl)-1-butanol #, 1-(4-tert-butylphenyl)-4-[4-[hydroxy-di(phenyl)methyl]piperidin-1-yl]butan-1-ol, Alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenyl-methyl)-1-piperidine butanol, 1-(4-tert-Butyl-phenyl)-4-[4-(hydroxy-diphenyl-methyl)-piperidin-1-yl]-butan-1-ol(Terfenadine)

ID: 771

InChIKey: GUHPRPJDBZHYCJ-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(S1)C(=O)C2=CC=CC=C2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5468
synonyms found at PubChem are:
tiaprofenic acid, 33005-95-7, Tiaprofensaeure, Surgam, Acido tiaprofenico, Acide tiaprofenique, 2-(5-benzoylthiophen-2-yl)propanoic acid, Acidum tiaprofenicum, 5-Benzoyl-alpha-methyl-2-thiopheneacetic acid, 2-(5-Benzyl-2-thienyl)propionsaeure, Acide tiaprofenique [INN-French], Acido tiaprofenico [INN-Spanish], Acidum tiaprofenicum [INN-Latin], FC 3001, RU 15060, Dom-tiaprofenic, Surgam SR, Tiaprofenic acid [INN:BAN:DCF:JAN], 2-[5-(phenylcarbonyl)-2-thienyl]propanoic acid, Surgam (TN), CHEBI:32221, Apo-Tiaprofenic Tablets, alpha-methyl-5-benzoyl-2-thienylacetic acid, EINECS 251-329-3, BRN 1380662, Tiaprofenic acid (JAN/INN), 5-benzoyl-alpha-methylthiophene-2-acetic acid, GUHPRPJDBZHYCJ-UHFFFAOYSA-N, 2-(5-Benzoyl-thiophen-2-yl)-propionic acid, DSSTox_CID_3665, 2-Thiopheneacetic acid, 5-benzoyl-alpha-methyl-, DSSTox_RID_77134, DSSTox_GSID_23665, Nu-Tiaprofenic, Novo-Tiaprofenic, PMS-Tiaprofenic, Surgam SA, tiaprofen, Tiaprofensaure, Suralgan, Tiaprofen (TN), NCGC00016815-01, Surgamyl (TN), 103667-49-8, Prestwick_814, CAS-33005-95-7, Tiaprofenic-200-Tab, Tiaprofenic-300-Tab, (RS)-Tiaprofenic acid, ACMC-20dh1z, ACMC-20i3qm, AC1L1KEZ, 2-Thiopheneacetic acid,5-benzoyl-a-methyl-, (aR)-, Prestwick0_000496, Prestwick1_000496, Prestwick2_000496, Prestwick3_000496, Tiaprofenic-200 - Tab, Tiaprofenic-300 - Tab, (+/-)-Tiaprofenic acid, D0S7VO, Epitope ID:131796, SCHEMBL25639, BSPBio_000391, 2-Thiopheneacetic acid, 5-benzoyl-.alpha.-methyl-, 5-18-08-00405 (Beilstein Handbook Reference), MLS002153845, SPBio_002312, BPBio1_000431, CHEMBL365795, DTXSID5023665, CTK4G9712, MolPort-006-126-627, BDBM223313, HMS1569D13, HMS2096D13, HMS2230E19, HMS3372D06, HMS3713D13, KS-000001NZ, Tox21_110627, GP9951, STL454339, (5-benzoyl-2-thienyl)-propionic acid, AKOS015969058, Tox21_110627_1, AC-8970, API0009145, CCG-220496, DB01600, TRA0080822, VZ23228, 2-(5-Benzoylthiophen-2-yl)propanoicacid, NCGC00179573-03, AK129846, RU-15060, SMR001233207, 2-(5-Benzoyl-2-thienyl)propanoic acid #, 2-(5-Benzoylthiophen-2-yl)propionic Acid, alpha-(5-benzoyl-2-thienyl)propionic acid, 2-Thiopheneacetic acid,5-benzoyl-a-methyl-, AX8152290, KB-125385, LS-152878, FT-0675220, (RS)-2-(5-benzoyl-2-thienyl)propanoic acid, D01325, 5-Benzoyl-.alpha.-methyl-2-thiopheneacetic acid, 005T957, SR-01000841193, 2-(5-Benzoyl-2-thienyl)propanoic acid, AldrichCPR, 2-[5-(phenylcarbonyl)thiophen-2-yl]propanoic acid, J-018971, SR-01000841193-2, BRD-A72988804-001-03-8

ID: 772

InChIKey: GVEZIHKRYBHEFX-NQQPLRFYSA-N
SMILES: C/C=C/C/C=C/CCC(=O)[C@@H]1[C@@H](O1)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5282054
synonyms found at PubChem are:
cerulenin, 17397-89-6, Helicocerin, UNII-MF286Y830Q, EINECS 241-424-8, NSC 116069, CHEMBL45627, 3-(1-Oxo-4,7-nonadienyl)oxiranecarboxamide, (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide, CHEBI:171741, Cerulenin, Cephalosporium caerulens, MF286Y830Q, 7,10-DODECADIENAMIDE, 2,3-EPOXY-4-OXO-, Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, (2R-(2alpha,3alpha(4E,7E)))-, (2R,3S)-2,3-Epoxy-4-oxo-7E,10E-dodecadienamide, (2S)(3R)-2,3-Epoxy-4-oxo-7,10-dodecadienoylamide, 2,3-Epoxy-4-oxo-7,10-dodecadienamide, (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide, (2r,3s)-3-(nona-4,7-dienoyl)oxirane-2-carboxamide, (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide, (2R-(2alpha,3alpha(4E,7E)))-3-(1-Oxonona-4,7-dienyl)oxirane-2-carboxamide, 2,3-Epoxy-4-oxo-7,10-dodecadienoylamide, SR-05000002362, (+)-Cerulenin, AC1NQZF4, (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide, AC1Q5H5H, SCHEMBL41207, BSPBio_001276, MLS006010821, DTXSID2040995, CHEBI:94649, MolPort-016-580-730, HMS1362P17, HMS1792P17, HMS1990P17, HMS3403P17, HMS3649F20, HY-A0210, ZINC4102315, 1668AH, BDBM50009248, MFCD00077686, 2,3-Epoxy-4-oxo-10-dodecadienamide, AKOS030568044, CCG-208171, CS-6992, IDI1_002233, NCGC00163492-01, NCGC00163492-02, BC653191, G237, LS-63388, SMR000058786, C12058, 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide, J-010957, SR-05000002362-2, SR-05000002362-3, BRD-K52075040-001-02-2, BRD-K52075040-001-03-0, BRD-K52075040-001-04-8, Cerulenin, >=98% (HPLC), from Cephalosporium caerulens, (2R,3S)-3-[(4E,7E)-4,7-Nonadienoyl]-2-oxiranecarboxamide, 2R,3S)-3-[(4E,7E)-Nona-4,7-dienoyl]oxirane-2-carboxamide, 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide(Cerulenin), Oxiranecarboxamide, 3-[(4E,7E)-1-Oxo-4,7-nonadienyl]-, (2R,3S)-, Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, (2R-(2-alpha,3-alpha(4E,7E)))-, Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, (2R-(2-alpha,3-alpha(4E,7E)))- (9CI), 1X9

ID: 773

InChIKey: GVJHHUAWPYXKBD-IEOSBIPESA-N
SMILES: CC1=C(C(=C2CC[C@@](OC2=C1C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 14985
synonyms found at PubChem are:
VITAMIN E, alpha-Tocopherol, D-alpha-Tocopherol, 59-02-9, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol, (R,R,R)-alpha-Tocopherol, Phytogermine, Eprolin, (2R,4'R,8'R)-alpha-Tocopherol, dl-a-Tocopherol, Aquasol E, a-Tocopherol, Tocopherol alpha, a-Vitamin E, 10191-41-0, alpha-Tocopherol, D-, (+)-|A-Tocopherol, 2074-53-5, Vitamin Ea, Mixed tocopherols, (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, D-alpha tocopherol, Syntopherol, Denamone, Viteolin, Esorb, Tocopherol (R,S), UNII-N9PR3490H9, alpha Tocopherol, 2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol, Evitaminum, Profecundin, Waynecomycin, Almefrol, Emipherol, Ephanyl, Epsilan, Etamican, Tokopharm, Vascuals, Viprimol, Vitayonon, Etavit, Ilitia, Verrol, Evion, alpha-Tokoferol, BPBio1_000362, alpha-Vitamin E, Vitamin E alpha, Vitaplex E, Eprolin S, Viterra E, CHEBI:18145, E Prolin, Spavit E, GVJHHUAWPYXKBD-IEOSBIPESA-N, ido-E, Endo E, N9PR3490H9, Vita E, EINECS 215-798-8, Lan-E, Med-E, (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol, Antisterility vitamin, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol, alpha-Tocopherol acid, Tenox GT 1, 1406-18-4, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-, Rhenogran Ronotec 50, Vi-E, Covitol F 1000, alpha-Tocopherol, DL-, E 307 (tocopherol), (+-)-alpha-Tocopherol, DSSTox_CID_6339, (all-R)-alpha-Tocopherol, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, DSSTox_RID_78103, DSSTox_GSID_26339, 18920-62-2, E-Oil 1000, CCRIS 3588, CCRIS 5853, HSDB 2556, .alpha.-Tocopherol, EINECS 200-412-2, EINECS 233-466-0, NSC 20812, (2R)-2-((4R,8R)-4,8,12-trimethyltridecyl)-2,5,7,8-tetramethylchroman-6-ol, BRN 0094012, CAS-59-02-9, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R-(2R*(4R*,8R*)))-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R-[2R*(4R*,8R*)]]-, SMR000471844, VIV, E 307, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol, Phytogermin, Daltose, Palmvtee, alpha-Tocoferol, Vitec, (+-)-Med-E, Vitamin Ealpha, a-D-Tocopherol, Pheryl-E, Vita plus E, Amino-Opti-E, Gordo-Vite E, d-..-Tocopherol, alpha-D-Tocopherol, NCGC00016688-02, Vitamin E, liquid, (+)--tocopherol, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-, E-Vitamin succinate, Prestwick_653, EINECS 218-197-9, .alpha.-Vitamin E, (+)-a-Tocopherol, NSC 82623, RRR-alpha-tocopherol, RRR-alpha-tocopheryl, Vitamin E (liquid), Vitamin E [USP], ()-alpha-Tocopherol, delta-alpha-tocopherol, alpha-delta-Tocopherol, E-Complex-600, Vitamin E (D-form), CHEMBL47, (R,R,R)-a-Tocopherol, Prestwick3_000404, Vitamin Plus E Softgells, DL-all-rac- -Tocopherol, (+)-.alpha.-Tocopherol, (+/-)-alpha-Tocopherol, all-rac-alpha-Tocopherolum, .Alpha.-tocopherol, DL-, bmse000600, EC 200-412-2, AC1L24WT, AC1Q2QG9, E-200 I.U. Softgels, SCHEMBL3097, DL-all-rac-alpha-Tocopherol, UNII-H4N855PNZ1, BIDD:PXR0174, BSPBio_000328, MLS001066396, MLS001335981, MLS001335982, BIDD:ER0562, T1539_SIGMA, H4N855PNZ1, Jsp004249, .ALPHA.-TOCOPHEROL, D-, DTXSID0026339, (2R,4'R,8'R)-a-Tocopherol, Vitamin E (DL-alpha-Tocopherol), ((addition))-(alpha)-Tocopherol, (2R,4'R,8'R)-2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- -benzopyran-6-ol, MolPort-000-735-907, HMS2096A10, HMS2231G08, DL-alpha-Tocopherol, 97% 50g, HY-N0683, ZINC4095858, Tox21_110563, Tox21_113208, Tox21_202081, LMPR02020001, MFCD00006848, MFCD00072045, AKOS004910417, CS-8161, DB00163, LS-7727, MCULE-3684036705, NCGC00142625-01, NCGC00142625-04, NCGC00142625-05, NCGC00142625-06, NCGC00142625-07, NCGC00142625-10, NCGC00259630-01, (2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, AJ-47974, AK305272, AN-22333, AS-13990, E307, M349, P500, SC-18444, SC-19194, ST073358, AX8156561, KB-308953, LS-173092, TR-000459, FT-0600386, FT-0624406, C02477, d-alpha, d-beta, d-gamma & d-delta tocopherols, I06-2201, I14-8436, Q-201932, W-107596, W-109164, I14-16780, 07AA93F0-3339-4EEC-B50B-ADB70F657087, UNII-7QWA1RIO01 component GVJHHUAWPYXKBD-IEOSBIPESA-N, UNII-N53I4V2IA6 component GVJHHUAWPYXKBD-IEOSBIPESA-N, UNII-R0ZB2556P8 component GVJHHUAWPYXKBD-IEOSBIPESA-N, (+)-alpha-Tocopherol, from vegetable oil, Type V, ~1000 IU/g, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol, (+)-alpha-Tocopherol, Type VI, from vegetable oil, neat (liquid, >=0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, >=1000 IU/g, (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol, (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol, 11105-14-9, 121854-78-2, 2,5,7,8-Tetramethyl-2-(4 inverted exclamation marka,8 inverted exclamation marka,12 inverted exclamation marka-trimethyltridecyl)-6-chromanol, 21-59-0, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 2R- 2R*(4R*,8R*) -, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R*(4R*,8R*))-(+-)- (9CI), 364-49-8

ID: 774

InChIKey: GWBBVOVXJZATQQ-UHFFFAOYSA-L
SMILES: CC(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 23894
synonyms found at PubChem are:
Etidronate disodium, 7414-83-7, Didronel, Sodium etidronate, Disodium etidronate, Disodium ethydronate, Sodium ethidronate, Sodium ethydronate, Didronel R, Disodium ethanol-1,1-diphosphonate, Etidronsaeure dinatriumsalz, Disodium (1-hydroxyethylidene)diphosphonate, UNII-M16PXG993G, Disodium 1-hydroxyethylidene phosphonate, Disodium ethane-1-hydroxy-1,1-diphosphonate, Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt, EINECS 231-025-7, Etidronate disodium hydrate, SM-5600, (1-Hydroxyethylidene)diphosphonic acid, disodium salt, Disodium dihydrogen (1-hydroxyethylidene)diphosphonate, Etidronic Acid Disodium Salt, Etidronic acid, disodium salt, 1-Hydroxyethylidene-1,1-diphosphonic acid disodium salt, (1-Hydroxyethane-1,1-diyl)diphosphonic acid disodium salt, CHEBI:4906, M16PXG993G, Ethane-1-hydroxy-1,1-diphosphonate, disodium salt, Disodium dihydrogen (1-hydroxyethylidene)bisphosphonate, Ethane-1-hydroxy-1,1-diphosphonic acid, disodium salt, Phosphonic acid, (1-hydroxyethylidene)di-, disodium salt, CAS-7414-83-7, DSSTox_CID_9671, disodium hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate, DSSTox_RID_78804, DSSTox_GSID_29671, 1-Hydroxyethane-1,1-diphosphonic Acid Disodium Salt, W-104431, Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate, disodium (1-hydroxyethane-1,1-diyl)bis[hydrogen (phosphonate)], Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2), NCGC00159352-02, C2H6Na2O7P2, Calcimux, Etidron, Ostedron, Xydifon, disodium;hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate, Etidronate Disodium [USAN:JAN], Turpinal 2NZ, Didronel (TN), Sequion 10Na2, Etidronate disodium [USAN:USP:JAN], Fostex NZ 2, Prestwick_1061, Etidronic acid disodium, Etidronate disodium salt, D00XUN, AC1L2N2E, C3H8O6P2.2Na, Etidronate disodium hydrate 1g, Etidronate disodium salt hydrate, CHEMBL1201042, DTXSID1029671, CTK8F9685, TF 133B, Etidronate disodium (JP17/USP), GWBBVOVXJZATQQ-UHFFFAOYSA-L, HMS1570N07, HMS2093P03, HMS2097N07, BCP22743, Etidronic acid disodium salt hydrate, Tox21_111596, BA 49280E, GP3560, KM1595, MFCD00152567, AKOS015961949, Tox21_111596_1, 7414-83-7 (DISODIUM), AC-2078, CCG-213569, KS-1297, NCGC00017072-01, NCGC00179380-04, AN-14328, K264, Sodium Ethane-1-hydroxy-1,1-diphosphonate, Disodium 1-Hydroxyethane-1,1-diphosphonate, LS-106639, D4159, FT-0630369, D00314, A838033, Disodium (1-Hydroxyethylidene)-1,1-bisphosphonate, Etidronate disodium hydrate, >=97% (NMR), solid, 1-Hydroxyethane 1,1-Diphosphonic Acid Disodium Salt, sodium 1-hydroxyethane-1,1-diylbis(hydrogenphosphonate), 1-Hydroxyethane-1,1-diphosphonic acid disodium salt hydrate, P,P'-(1-Hydroxyethylidene)bisphosphonic Acid Sodium Salt, disodium [1-[oxidanidyl(oxidanyl)phosphoryl]-1-oxidanyl-ethyl]-oxidanyl-phosphinate, 187285-10-5, BCP9000614, I04-0175, SCHEMBL1515049, AKOS015892741, API0002650, KB-309343

ID: 775

InChIKey: GWBJPNAWYMBRLQ-UHFFFAOYSA-N
SMILES: CC1CCC2C(CC2(C)C)C(=C)CCC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4552810
synonyms found at PubChem are:
DIHYDROCARYOPHYLLEN-5-ONE, Bicyclo[7.2.0]undecan-5-one, 6,10,10-trimethyl-2-methylene-, 109278-26-4, KBio2_006981, Spectrum_001365, ACMC-20mc5n, SpecPlus_000369, AC1NC3WZ, Spectrum2_001783, Spectrum3_001329, Spectrum4_001734, Spectrum5_000528, BSPBio_003057, KBioGR_002148, KBioSS_001845, SPECTRUM307055, DivK1c_006465, SPBio_001705, CHEMBL1318499, CTK0D5874, KBio1_001409, KBio2_001845, KBio2_004413, KBio3_002277, DTXSID50404190, GWBJPNAWYMBRLQ-UHFFFAOYSA-N, CCG-38432, SDCCGMLS-0066922.P001, NCGC00095859-01, NCGC00095859-02, 4,11,11-trimethyl-8-methylenebicyclo[7.2.0]undecan-5-one, 4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undecan-5-one

ID: 776

InChIKey: GWEHVDNNLFDJLR-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC(=O)NC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 7595
synonyms found at PubChem are:
1,3-Diphenylurea, N,N'-Diphenylurea, 102-07-8, CARBANILIDE, Diphenylurea, Diphenylcarbamide, Urea, N,N'-diphenyl-, s-Diphenylurea, sym-Diphenylurea, Acardite I, Acardite, N-Phenyl-N'-phenylurea, 1,3-Diphenylcarbamide, Karbanilid, N,N'-Difenylmocovina, USAF EK-534, Urea, 1,3-diphenyl-, Karbanilid [Czech], 1,3-diphenyl-urea, AD 30, UNII-94YD8RMX5B, NSC 227401, N,N'-Difenylmocovina [Czech], CCRIS 4634, HSDB 2757, Urea-based compound, 7, EINECS 203-003-7, BRN 0782650, 94YD8RMX5B, AI3-52320, CHEBI:41320, GWEHVDNNLFDJLR-UHFFFAOYSA-N, Urea,3-diphenyl-, Urea,N'-diphenyl-, WLN: RMVMR, F0316-0002, N-phenyl(phenylamino)carboxamide, N'N'-Diphenyl urea, SR-01000398115, bis-phenyl-urea, Zeonet U, 2zjf, n,n'-diphenyl-urea, N, N'-diphenylurea, N,N'-diphenyl urea, 1, 3-Diphenylurea, Kinome_598, Kinome_627, Spectrum_000422, SpecPlus_000406, Spectrum2_001838, Spectrum3_001328, Spectrum4_001561, Spectrum5_000182, DSSTox_CID_5183, 1 pound not3-diphynylurea, D0X7IM, AC1L1P4D, 1,3-Diphenylurea, 98%, DSSTox_RID_77698, DSSTox_GSID_25183, Oprea1_527136, BSPBio_003055, CBDivE_002165, KBioGR_002082, KBioSS_000902, SPECTRUM211126, 4-12-00-00741 (Beilstein Handbook Reference), KSC175E2F, MLS002207104, DivK1c_006502, SCHEMBL133103, SPBio_001915, CHEMBL354676, DTXSID2025183, BDBM25725, CTK0H5222, KBio1_001446, KBio2_000902, KBio2_003470, KBio2_006038, KBio3_002275, KS-00000WTV, NSC8485, 3e85, MolPort-000-393-991, ACMC-209800, NSC-8485, RKL10128, Tox21_200068, ANW-14638, CCG-38465, ICCB1_000093, LS-354, MFCD00003017, N,N''-Diphenylurea, 98% 25g, NSC227401, SBB058217, STK328350, ZINC12416741, AKOS000312994, DB07496, MCULE-4684667909, NSC-227401, RTR-000546, SDCCGMLS-0066513.P001, TRA0086633, VZ36373, NCGC00091344-01, NCGC00091344-02, NCGC00091344-03, NCGC00091344-04, NCGC00091344-05, NCGC00257622-01, AC-12855, AJ-62233, AN-24596, CAS-102-07-8, CJ-14055, CJ-14056, KB-79151, SMR000112141, AB1002487, TR-000546, EU-0067898, FT-0606720, ST45141119, L-5305, 1,3-Diphenylurea, Vetec(TM) reagent grade, 98%, AQ-917/40171059, SR-01000398115-1, SR-01000398115-2, W-108886, BRD-K13027645-001-02-0, I14-17762, N,N inverted exclamation marka-Diphenylurea; Carbanilide, Carbanalide Solution, 100 mg/L, 1 ml (RM, ISO GUIDE 34), InChI=1/C13H12N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h1-10H,(H2,14,15,16

ID: 777

InChIKey: GWJOFBXSBDVUMH-UHFFFAOYSA-N
SMILES: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)O.C=O.C(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16219992
synonyms found at PubChem are:
Tyloxapol, BioXtra, Tyloxapol, nonionic surfactant, AKOS024435251, Tyloxapol, United States Pharmacopeia (USP) Reference Standard

ID: 778

InChIKey: GXDALQBWZGODGZ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2247
synonyms found at PubChem are:
astemizole, Hismanal, 68844-77-9, Histaminos, Paralergin, Laridal, Retolen, Alermizol, Astemison, Astemizol, Histamen, Kelp, Astemizolum, Astemisan, Hestazol, Histazol, Wareezol, Metodih, Novo-mastizol A, Astemizol [German], Metodik, Waruzol, Astemizol [INN-Spanish], Astemizolum [INN-Latin], Astemisol, Nono-Nastizol A, [3H]Astemizole, Astemizole [USAN:BAN:INN], C28H31FN4O, CCRIS 7595, R 42512, GNF-PF-2461, HSDB 6799, UNII-7HU6337315, HISMANAL (TN), EINECS 272-441-9, R-43512, BRN 4830190, Astemizole (JAN/USP/INN), 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole, 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole, 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine, MLS000028667, CHEBI:2896, CHEMBL296419, MJD-30, GXDALQBWZGODGZ-UHFFFAOYSA-N, R 43 512, R-43-512, NCGC00016913-08, SMR000058911, CAS-68844-77-9, DSSTox_CID_110, 7HU6337315, 1-(4-Fluorobenzyl)-2-(1-[4-methoxyphenethyl]piperidin-4-yl)aminobenzimidazole, Benzimidazole, 1-(p-fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)-, DSSTox_RID_75373, DSSTox_GSID_20110, 1-((4-Fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)- 1H-benzimidazol-2-amine, 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)eth l)-4-piperidinyl)-, 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-, 1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-, W-104654, Fustermizol, Hubermizol, Astemina, Astesen, Esmacen, Rifedot, Romadin, Simprox, Emdar, Rimbol, Urdrim, Novo-nastizol a, Astemizol Alonga, Hestazol, Kelp, Laridal, Retolen, Wareezol, HSBD 6799, BRN 4830190, Alonga, Astemizol, 1-(4-fluorobenzyl)-2-(1-(4-methoxyphenethyl)piperidin-4-yl)aminobenzimidazole, 1-(4-fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, 1-(p-Fluorobenzyl)-2-[[1-(p-methoxyphenethyl)-4-piperidyl]amino]benzimidazole, 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidyl]benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-(1-{2-[4-(methyloxy)phenyl]ethyl}piperidin-4-yl)-1H-benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine, Astemizol ratiopharm, ratiopharm, Astemizol, SR-01000003168, Astemizole,(S), Prestwick_35, Astemizole Byk Brand, Astemizole Diba Brand, Astemizole ICN Brand, Astemizole Vita Brand, Astemizole [USAN:USP:INN:BAN:JAN], Astemizole Elfar Brand, Astemizole Lesvi Brand, Astemizole Merck Brand, Astemizole Septa Brand, Opera_ID_62, Astemizole Alacan Brand, Astemizole Alonga Brand, Astemizole Esteve Brand, Astemizole Urbion Brand, Spectrum_000448, Astemizole McNeil Brand, Byk Brand of Astemizole, Astemizole Fustery Brand, Astemizole Janssen Brand, Astemizole Medinsa Brand, Astemizole Smaller Brand, ICN Brand of Astemizole, Diba Brand of Astemizole, Vita Brand of Astemizole, AlacanBrand of Astemizole, Prestwick0_000136, Prestwick1_000136, Prestwick2_000136, Prestwick3_000136, Spectrum2_001732, Spectrum3_001072, Spectrum4_001223, Spectrum5_001239, Elfar Brand of Astemizole, Lesvi Brand of Astemizole, Merck Brand of Astemizole, Septa Brand of Astemizole, Astemizole Senosiain Brand, Alonga Brand of Astemizole, Astemizole ratiopharm Brand, D0Y2HR, Esteve Brand of Astemizole, McNeil Brand of Astemizole, UPCMLD-DP024, Urbion Brand of Astemizole, R43512, cid_2247, Fustery Brand of Astemizole, Janssen Brand of Astemizole, Medinsa Brand of Astemizole, SCHEMBL4385, Smaller Brand of Astemizole, REGID_for_CID_2247, BSPBio_000212, BSPBio_002684, KBioGR_001686, KBioSS_000928, Astemizole, [O-Methyl-3H], MLS001148073, Senosiain Brand of Astemizole, DivK1c_000039, ratiopharm Brand of Astemizole, SPECTRUM2300094, SPBio_001804, SPBio_002151, AC1L1D93, BPBio1_000234, GTPL2603, Reig Jofre Brand of Astemizole, Astemizole, >=98% (HPLC), DTXSID9020110, UPCMLD-DP024:001, BDBM24226, CTK8F7845, HMS500B21, KBio1_000039, KBio2_000928, KBio2_003496, KBio2_006064, KBio3_001904, MolPort-003-666-765, NINDS_000039, HMS1568K14, HMS1922L12, HMS2090F14, HMS2093L18, HMS2095K14, HMS2234M17, HMS3373B08, HMS3712K14, Pharmakon1600-02300094, ZINC601274, BCP16088, Tox21_110680, Tox21_200095, BG0092, CCG-39453, MFCD00153919, NSC329963, NSC759570, STL301859, AKOS005064371, Tox21_110680_1, API0002918, DB00637, KS-5171, MCULE-9080712110, NSC-329963, NSC-759570, IDI1_000039, QTL1_000010, NCGC00016913-01, NCGC00016913-02, NCGC00016913-03, NCGC00016913-04, NCGC00016913-05, NCGC00016913-06, NCGC00016913-07, NCGC00016913-09, NCGC00016913-10, NCGC00016913-11, NCGC00016913-12, NCGC00016913-14, NCGC00018288-01, NCGC00022520-03, NCGC00022520-04, NCGC00022520-05, NCGC00022520-06, NCGC00022520-07, NCGC00257649-01, AJ-23671, AN-38015, BC218650, K146, LS-32978, SC-18314, ACM1189961394, SBI-0051891.P002, AB00052413, B7409, FT-0622497, ST51014896, 5318-EP2270008A1, 5318-EP2281815A1, 5318-EP2292617A1, 5318-EP2292619A1, 5318-EP2295409A1, 5318-EP2301933A1, 5318-EP2305640A2, 5318-EP2305659A1, 5318-EP2308562A2, 5318-EP2311827A1, 5318-EP2314590A1, 5318-EP2371811A2, C06832, D00234, AB00052413-18, AB00052413_19, 844A779, L001015, R 43,512, SR-01000003168-2, SR-01000003168-4, BRD-K37249724-001-05-9, BRD-K37249724-001-16-6, Astemizole, United States Pharmacopeia (USP) Reference Standard, 1-(4-fluorobenzyl)-N-(1-(4-methoxyphenethyl)piperidin-4-yl)-1H-benzo[d]imidazol-2-amine, {1-[(4-fluorophenyl)methyl]benzimidazol-2-yl}{1-[2-(4-methoxyphenyl)ethyl](4-p iperidyl)}amine, 1-(4-Fluorobenzyl)-N-(1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl)-1H-benzimidazol-2-amine #, 1-(4-fluorophenylmethyl)-N-{1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl}-1H-benzimidazol-2-amine, 1-[(fluorophenyl)-methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine, 1H-Benzimidazol-2-amine,1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)ethyl)-4-piperdinyl)

ID: 779

InChIKey: GXEKYRXVRROBEV-UHFFFAOYSA-N
SMILES: C1CC2C(C(C1O2)C(=O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3225
synonyms found at PubChem are:
endothall, Endothal, Hydout, Tri-Endothal, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, Endothal technical, Hydrothal-47, Hydrothal-191, Aquathol, Aquothol, Hydrothol, Herbon pennout, Endothall Weed Killer, 145-73-3, 3,6-endo-Oxohexahydrophthalic acid, RCRA waste number P088, 3,6-endo-Oxyphthalic acid hexahydro-, 3,6-Endoxohexahydrophthalic acid, 3,6-Endooxyphthalic acid, hexahydro-, NSC 112771, Phthalic acid, hexahydro-3,6-endo-oxy-, Aquathol Plus, Des-i-cate, GXEKYRXVRROBEV-UHFFFAOYSA-N, Endothal [BSI], 1,2-Cyclohexanedicarboxylic acid, 3,6-endo-epoxy-, Endothall [ANSI], NSC237771, Endothall sodium, 1,2-Benzenedicarboxylic acid, hexahydro-3,6-endo-oxy-, Caswell No. 421, Aquathol Plus Granular, Endothall Turf Herbicide, Endothal monohydrate, DSSTox_CID_4081, Disodium 3,6-endoxohexahydrophthalate, Herbicide 273, DSSTox_RID_77281, DSSTox_GSID_24081, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic acid, HSDB 391, 3,6-Endooxohexahydrophthalic acid, EINECS 205-660-5, EPA Pesticide Chemical Code 038901, CAS-145-73-3, 3,6-Epoxycyclohexane-1,2-dicarboxylic acid, RCRA waste no. P088, Niagrathal, NSC-112771, AC1L1FGE, 62059-43-2, 7-oxabicyclo[2.2.1]heptan-2,3-dicarbons, 1, 3,6-endo-epoxy-, 4-Bromophenylacetone,97%, AC1Q5TE1, Phthalic acid,6-endo-oxy-, CHEMBL8080, Lopac0_000542, SCHEMBL55158, BMK1-H1, 1, hexahydro-3,6-endo-oxy-, DTXSID7024081, CTK0H5601, MolPort-003-930-785, WLN: T55 A AOTJ CVQ DVQ, Tox21_202446, Tox21_300094, HSCI1_000365, NSC112771, AKOS024418784, CCG-204632, MCULE-1828714380, NSC-237771, NCGC00015419-02, NCGC00015419-03, NCGC00015419-04, NCGC00015419-05, NCGC00015419-06, NCGC00015419-07, NCGC00093930-01, NCGC00093930-02, NCGC00254025-01, NCGC00259995-01, 28874-46-6, LS-98710, TR-005743, EU-0100542, FT-0603356, E 7649, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylicacid, SR-01000075864, J-008144, SR-01000075864-1

ID: 780

InChIKey: GXOMMGAFBINOJY-SLINCCQESA-M
SMILES: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 64688
synonyms found at PubChem are:
Dicloxacillin sodium, Sodium dicloxacillin, 343-55-5, UNII-4CKS6MOL6Z, 4CKS6MOL6Z, Veracillin, CHEBI:34691, 13412-64-1, P 1011, Dichlor-Stapenor, 3116-76-5 (Parent), CPD000539527, SMR000539527, Dicloxacillin sodium anhydrous, Prestwick_917, EINECS 206-444-3, Dicloxacillin sodium salt, AC1Q1VUP, Dicloxyacillin sodium salt, sodium dicloxacillin(1-), SCHEMBL41516, MLS001304055, MLS001304195, CHEMBL26570, SPECTRUM1500238, C19H16Cl2N3O5S.Na, HMS502A20, DTXSID60187861, MolPort-002-512-432, HMS1569I22, HMS1920E18, HMS2091M08, HMS2875M16, HMS3259F06, 3-(2,6-Dichlorophenyl-5-methyl-4-isoxazolyl penicillin, Sodium (3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)penicillin, 2374AH, BG0166, CCG-40199, AKOS030491496, NC00697, SAM002589922, SAM002589990, D-2270, AB01566907_01, Dicloxacillin sodium salt, Antibiotic for Culture Media Use Only, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2alpha,6beta))-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, monosodium salt, natrium-(2s,5r,6r)-6-({[3-(2,6-dichlorphenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat, sodium (2S,5R,6R)-6-(3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, Sodium (2S-(2alpha,5alpha,6beta))-6-(((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, sodium 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylate, MolPort-046-033-679

ID: 781

InChIKey: GYBONEHHSUABAO-UHFFFAOYSA-N
SMILES: CN(CCC1=CC(=C(C=C1)OC)OC)CCC2=CC(=C(C=C2)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 56017
synonyms found at PubChem are:
MR-827, YS 035, 3,3',4,4'-Tetramethoxy-N-methyldiphenethylamine hydrochloride, DIPHENETHYLAMINE, N-METHYL-3,3',4,4'-TETRAMETHOXY-, MONOHYDROCHLORIDE, Benzeneethanamine, N-(2-(3,4-dimethoxyphenyl)ethyl)-3,4-dimethoxy-N-methyl-, hydrochloride, N,N-Bis(2-(3,4-dimethoxyphenyl)ethyl)methylamine hydrochloride, AC1L1K8U, LS-62864, bis[2-(3,4-dimethoxyphenyl)ethyl]-methylazanium chloride, YS-035 hydrochloride, 89805-39-0, YS-035, 33978-72-2, SR-01000075298, N,N-Bis-(3,4-dimethoxyphenylethyl)-N-methylamine hydrochloride, ACMC-20fbbm, AC1OCEPU, MLS000860015, SCHEMBL7194533, CHEMBL1256839, CTK3E8370, MolPort-003-960-222, Tox21_501220, AKOS024458009, CCG-222524, LP01220, NCGC00094465-01, NCGC00261905-01, SMR000326873, B6295, EU-0101220, J-019405, SR-01000075298-1, SR-01000075298-3, bis[2-(3,4-dimethoxyphenyl)ethyl](methyl)amine hydrochloride, YS-035 hydrochloride, analytical standard, for drug analysis, 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylethanamine hydrochloride, N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxy-N-methyl-benzeneethanamine hydrochloride, N-(-2-[3,4- paragraph signthorn(1/4)xNo+/-(1/2)>>u]OO>>u)-3,4- paragraph signthorn(1/4)xNo>>u-N-(1/4)x>>u+/-(1/2)OO degrees .

ID: 782

InChIKey: GYDJEQRTZSCIOI-UHFFFAOYSA-N
SMILES: C1CC(CCC1CN)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5526
synonyms found at PubChem are:
tranexamic acid, 1197-18-8, Cyklokapron, Tranexamsaeure, Trans AMCHA, Tranhexamic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acid, Transamin, 4-(Aminomethyl)cyclohexanecarboxylic acid, Amstat, Tamcha, Amikapron, Anvitoff, Cyclocapron, Ugurol, trans-Amcha, Frenolyse, Rikavarin, Trasamlon, Carxamin, Emorhalt, Tranexan, Mastop, Rikavarin-S, AMCA, AMCHA, 701-54-2, Exacyl, tranexmic acid, 1197-17-7, Hexapromin, Transamlon, Hexatron, Spiramin, Tranex, trans-Tranexamic acid, trans-4-Aminomethylcyclohexane-1-carboxylic acid, Acidum tranexamicum, Acido tranexamico, Acide tranexamique, cis-AMCHA, Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-, Lysteda, cis-4-(Aminomethyl)cyclohexanecarboxylic acid, BAY 3517, CL 65336, RP 18,429, cis-4-Aminomethylcyclohexane-1-carboxylic acid, cis-Tranexamic Acid, t-AMCHA, trans-p-(Aminomethyl)cyclohexanecarboxylic acid, Tranexamic acid cis-form, Acide tranexamique [INN-French], Acido tranexamico [INN-Spanish], Acidum tranexamicum [INN-Latin], DV 79, DV-79, 4-(Aminomethyl)-Cyclohexanecarboxylic Acid, 4-(aminomethyl)cyclohexane-1-carboxylic acid, Cyclohexanecarboxylic acid, 4-(aminomethyl)-, Rikavarin (TN), Transamin (TN), Cyklokapron (TN), UNII-37YD696II6, UNII-6T84R30KC1, HAKU, DV79, CL-65336, trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid, KABI 2161, EINECS 214-818-2, trans-1-Aminomethylcyclohexane-4-carboxylic acid, NSC 291305, Tranexamic acid [USAN:INN:BAN:JAN], trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid, trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid, Tranexamic acid (Transamin), BRN 2207452, (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid, Retavase, CHEBI:48669, GYDJEQRTZSCIOI-LJGSYFOKSA-N, 37YD696II6, 6T84R30KC1, ALBB-006013, Cyclohexanecarboxylic acid, 4-(aminomethyl)-, cis-, NSC291305, trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester, 4-aminomethylcyclohexanecarboxylic acid, NCGC00016569-01, CAS-1197-18-8, trans-4-(Aminomethyl)cyclohexane-carboxylic acid, cis-4-(Aminomethyl)-1-cyclohexanecarboxylic Acid, AMH, rel-(1r,4r)-4-(Aminomethyl)cyclohexanecarboxylic acid, rel-(1R,4R)-4-(aminomethyl)cyclohexane-1-carboxylic acid, Amchafibrin, SR-05000001794, tranexamate, tranol, zataranax, Femstrual, Tranesamic acid, 1ceb, Cyclo-F, Prestwick_476, Tranexamic Acid,(S), PubChem19810, Spectrum_001391, Tranexamic acid [USAN:USP:INN:BAN:JAN], AC1L1KJH, Prestwick0_000171, Prestwick1_000171, Prestwick2_000171, Prestwick3_000171, Spectrum2_000655, Spectrum3_001189, Spectrum4_000046, Spectrum5_001258, ACMC-209a3u, ACMC-20h19o, CHEMBL877, D05HXX, DSSTox_CID_25350, DSSTox_RID_80817, DSSTox_GSID_45350, Oprea1_786414, SCHEMBL16974, BSPBio_000061, BSPBio_002837, KBioGR_000511, KBioSS_001871, 3-14-00-00868 (Beilstein Handbook Reference), KSC489O4L, 701-54-2 tranexamic acid, DivK1c_000655, SCHEMBL186034, SCHEMBL349408, SPECTRUM1502026, SPBio_000689, SPBio_001982, AC1Q50F3, AC1Q546D, AC1Q5U04, BPBio1_000069, CHEMBL292500, GTPL6573, SCHEMBL6885575, SCHEMBL9885628, 701-54-2 (cis+trans), FMOC-(R)-2-aminobutyric acid, DTXSID3045350, CHEBI:94518, CTK0H8184, CTK3I9745, HMS502A17, KBio1_000655, KBio2_001871, KBio2_004439, KBio2_007007, KBio3_002337, KS-00000IPI, WLN: L6TJ AVQ D1Z -T, GYDJEQRTZSCIOI-KNVOCYPGSA-N, GYDJEQRTZSCIOI-UHFFFAOYSA-N, MolPort-001-792-390, MolPort-002-512-008, NINDS_000655, HMS1568D03, HMS1921F08, HMS2092P03, HMS2095D03, HMS3712D03, Pharmakon1600-01502026, WT319, BCP13133, BCP18146, HY-B0149, KS-00000NS2, ZINC1542907, Tox21_110500, Tranexamic acid (JP15/USAN/INN), Tranexamic acid (JP17/USAN/INN), AN-646, ANW-17368, BBL004469, BDBM50428067, CCG-39692, HTS001347, MFCD00001466, NSC758176, s1875, SBB006715, STK503668, Tranexamic Acid(Random Configuration), AKOS005171632, AKOS015854573, AKOS024257901, ZINC100007011, ZINC100071256, AC-4687, AM84352, BS-3867, CS-1965, DB00302, MCULE-6087008336, NSC-291305, NSC-758176, RP22118, RTX-010404, TRA0027406, 4-Aminomethyl-cyclohexanecarboxylic acid, AMCA|||AMCHA|||HAKU|||TAMCHA, IDI1_000655, NCGC00016569-02, NCGC00016569-03, NCGC00016569-04, NCGC00016569-05, NCGC00016569-06, NCGC00016569-08, NCGC00016569-09, NCGC00094944-01, NCGC00094944-02, p-(Aminomethyl)cyclohexanecarboxylic acid, AJ-26859, AN-47328, BC215624, BP-12345, H967, LS-56611, LS-56612, SC-19036, SC-90830, Trans-p-(Aminomethyl)cyclohexanecarboxylic, TS-02090, 4-(Aminomethyl);cyclohexanecarboxylic acid, SBI-0051705.P002, trans 4aminomethylcyclohexanecarboxylic acid, AB0013391, AB1003647, DB-074265, KB-271963, TR-023271, Trans-4-aminomethylcyclohexylcarboxylic acid, trans-p-Aminomethylcyclohexanecarboxylic acid, A0236, AB00052260, BB 0260034, CS-0055045, FT-0654339, FT-0675360, FT-0700806, LT00159441, ST50307111, trans 4-aminomethylcyclohexanecarboxylic acid, trans-4-aminomethylcyclohexanecarboxylic acid, 4-?(aminomethyl)?-Cyclohexanecarboxyli?c acid, cis-4-aminomethyl-1-cyclohexanecarboxylic acid, EN300-91506, trans-4(aminomethyl)cyclohexanecarboxylic acid, trans-4-(aminomethyl)cyclohexylcarboxylic acid, trans-4-aminomethyl cyclohexanecarboxylic acid, trans-4-aminomethyl-cyclohexanecarboxylic acid, trans-4-aminomethylcyclohexane carboxylic acid, C-5054, C12535, D01136, Q-9390, Trans-4-Aminomethyl cyclohexane carboxylic acid, trans4-aminomethylcyclohexane-1-carboxylic acid, AB00052260-04, AB00052260_05, AB00052260_06, trans-4 -(aminomethyl)cyclohexanecarboxylic acid, trans-4-(aminomethyl)-cyclohexanecarboxylic acid, trans-4-(Aminomethyl)cyclohexane carboxylic acid, trans-4-aminomethyl-1-cyclohexanecarboxylic acid, (1r,4r)-4-(aminomethyl)cyclohexanecarboxylic acid, (trans)-4-(aminomethyl)cyclohexanecarboxylic acid, 197T188, 204139-EP2277867A2, 204139-EP2280003A2, 4-trans-(Aminomethyl)cyclohexanecarboxylic acid #, Cyclohexanecarboxylicacid, 4-(aminomethyl)-, cis-, trans-?4-?(Aminomethyl)?cyclohexanecarboxylic acid, trans-4- (aminomethyl) cyclohexanecarboxylic acid, trans-4-(aminomethyl)- cyclohexane carboxylic acid, Trans-4-(aminomethyl)-cyclohexane carboxylic acid, trans-4-aminomethyl-1-cyclohexane carboxylic acid, 4alpha-Aminomethyl-1alpha-cyclohexanecarboxylic acid, CIS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLICACID, I04-0993, Q-201848, SR-05000001794-1, SR-05000001794-2, SR-05000001794-3, BRD-K15014948-001-01-2, I14-15270, trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%, 4-(Aminomethyl)cyclohexanecarboxylic acid;Tranexamic acid, F8886-7867, Z1741970429, Tranexamic acid, European Pharmacopoeia (EP) Reference Standard, Tranexamic acid, United States Pharmacopeia (USP) Reference Standard, trans-4-(Aminomethyl)cyclohexanecarboxylic acid (Tranexamic acid), Tranexamic acid, Pharmaceutical Secondary Standard; Certified Reference Material, 1510-00-5, 21573-60-4, 4-(azaniumylmethyl)cyclohexane-1-carboxylate, AC1LU7SV, STL454349, 4-(ammoniomethyl)cyclohexanecarboxylate, CJ-05286, 4-(ammoniomethyl)-1-cyclohexanecarboxylate, A804343

ID: 783

InChIKey: GZENKSODFLBBHQ-ILSZZQPISA-N
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@H]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)CC4)C)O)C)C(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 247839
synonyms found at PubChem are:
medrysone, Hydroxymesterone, Medrifar, Medrocort, Medritonic, Visudrisone, 2668-66-8, HMS Liquifilm, 6alpha-Methyl-11beta-hydroxyprogesterone, U-8471, UNII-D2UFC189XF, Medrysone (USAN), GSH 1043, NSC-63278, D2UFC189XF, 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione, Medriabioptal, Sedesterol, Spectramedryn, Medriusar, Medroftal, MLS000028714, HMS, CHEBI:34829, U 8471, Medrisone [DCIT], CPD000058693, SMR000058693, Medrysonum [INN-Latin], Medrisona [INN-Spanish], 11.beta.-Hydroxy-6.alpha.-methylprogesterone, 6.alpha.-Methyl-11.beta.-hydroxyprogesterone, DSSTox_CID_25371, DSSTox_RID_80833, DSSTox_GSID_45371, (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, 11beta-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione, 11.beta.-Hydroxy-6.alpha.-methylpregn-4-ene-3,20-dione, Medrysonum, Medrisona, Medrisone, EINECS 220-208-7, NSC 63278, 11beta-Hydroxy-6alpha-methylprogesterone, 6-alpha-Methyl-11-beta-hydroxyprogesterone, Progesterone, 11beta-hydroxy-6alpha-methyl-, 11-beta-Hydroxy-6-alpha-methylpregn-4-ene-3,20-dione, Medrysone [USAN:USP:INN], Prestwick_89, NCGC00016616-01, CAS-2668-66-8, Opera_ID_635, Prestwick0_000743, Prestwick1_000743, Prestwick2_000743, Prestwick3_000743, D04SFH, AC1L6L4H, HMS (TN), SCHEMBL4493, Pregn-4-ene-3,20-dione, 11-beta-hydroxy-6-alpha-methyl-, BSPBio_000726, MLS001076155, MLS002207230, MLS002222162, SPBio_002665, Pregn-4-ene-3,20-dione, 11-hydroxy-6-methyl-, (6alpha,11beta)-, BPBio1_000800, GTPL7086, CHEMBL1201173, DTXSID6045371, 6-Methyl-11-hydroxyprogesterone, BCBcMAP01_000088, MolPort-003-958-619, HMS1570E08, HMS2097E08, HMS2232F13, HMS3259A22, HMS3714E08, HY-B1076, NSC63278, ZINC3977945, Tox21_110526, 2534AH, AKOS024285179, Tox21_110526_1, CCG-220743, CS-4632, DB00253, NC00599, SMP1_000061, NCGC00179460-01, NCGC00179460-03, SAM002564258, ST082266, C14643, D02289, 668M668, C-44121, Progesterone, 11.beta.-hydroxy-6.alpha.-methyl-, SR-01000721900, SR-01000721900-3, BRD-K56515112-001-03-4, BRD-K56515112-001-21-6, Pregn-4-ene-3, 11.beta.-hydroxy-6.alpha.-methyl-, WLN: L E5 B666 OV MUTJ A1 CQ E1 FV1 L1, Medrysone, United States Pharmacopeia (USP) Reference Standard, Pregn-4-ene-3, 11-hydroxy-6-methyl-, (6.alpha.,11.beta.)-, Pregn-4-ene-3,20-dione, 11beta-hydroxy-6alpha-methyl- (8CI), (1S,2R,8S,10S,11S,14S,15S,17S)-14-acetyl-17-hydroxy-2,8,15-trimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-6-en-5-one, (1S,8S,10S,11S,14S,15S,17S,2R)-14-acetyl-17-hydroxy-2,8,15-trimethyl-5-oxotetr acyclo[8.7.0.0<2,7>.0<11,15>]heptadec-6-ene

ID: 784

InChIKey: GZOVEPYOCJWRFC-HZLVTQRSSA-N
SMILES: C1[C@@H]([C@H]1C(=O)O)[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5310956
synonyms found at PubChem are:
(2S,1'S,2'S)-2-(carboxycyclopropyl)glycine, L-CCG-l, L-Ccg-I, 117857-93-9, CCPG, L-CCG-1, CHEMBL280563, 3,4-Cyclopropylglutamate, L-2-(Carboxypropyl)glycine, (1S,2S)-2-[(1S)-1-amino-2-hydroxy-2-oxoethyl]cyclopropane-1-carboxylic acid, AC1NSJQB, L-CCGI, D0Z7CZ, Lopac0_000374, SCHEMBL664330, GTPL1368, (2S,3S,4S)-CCG, MolPort-003-940-678, HMS3261K09, ZINC2568218, Tox21_500374, BDBM50034504, AKOS006275493, CCG-204469, LP00374, NCGC00024541-02, NCGC00024541-03, NCGC00024541-04, NCGC00024541-05, NCGC00261059-01, B6264, C-237, EU-0100374, 2S,1'S,2'S)-2-(Carboxycyclopropyl)Glycine, (2S,1/'S,2/'S)-2-(Carboxycyclopropyl)glycine, SR-01000075799, 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid, J-003677, SR-01000075799-1, (1S,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanecarboxylic acid, 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-CCG), Cyclopropaneacetic acid, alpha-amino-2-carboxy-, (alphaS,1S,2S)-, (2S,1 inverted exclamation markaS,2 inverted exclamation markaS)-2-(Carboxycyclopropyl)glycine

ID: 785

InChIKey: GZSOSUNBTXMUFQ-YFAPSIMESA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281613
synonyms found at PubChem are:
diosmin, 520-27-4, Barosmin, Diosmine, Venosmine, Diosmil, Diosimin, Flebosten, Daflon, Diovenor, Tovene, Ven-Detrex, Veno-V, Diosminum, Rioven, Diosmetin 7-O-rutinoside, UNII-7QM776WJ5N, 7QM776WJ5N, CHEBI:4631, GZSOSUNBTXMUFQ-YFAPSIMESA-N, 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside, C28H32O15, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, Diosmetin-7-O-rutinoside, Buchu Resin, Diosmin, analytical standard, DSSTox_CID_25892, DSSTox_RID_81206, DSSTox_GSID_45892, 3',5,7-Trihydroxy-4'-methoxyflavone 7-rutinoside, 3',5,7-Trihydroxy-4'-methoxyflavone-7-(6-O-(-deoxy-alpha-L-mannopyraonsyl)-beta-D-glucopyranoside, 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromen-4-one, 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside, Litosmil, CAS-520-27-4, Diosmin [INN:BAN], Diosmin [INN-Spanish], Diosmine [INN-French], Diosminum [INN-Latin], SR-01000799147, flebosmil, CCRIS 7915, H-chromen-4-one, NCGC00095022-01, 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, Diosmin (INN), EINECS 208-289-7, Daflon (TN), Diosmin (8), SE 4601, AC1NQYQD, PubChem13043, Diosmin, 95% 5g, MLS001304032, SCHEMBL120870, CHEMBL231884, DTXSID4045892, 3',5-Dihydroxy-4'-methoxy-4-oxo-4H-chromen-7-ylrutosid, MolPort-000-756-016, BDBM153267, HMS2233P16, HMS3713L08, ACT05288, ZINC4098512, Tox21_111392, 3',5-Dihydroxy-4'-methoxy-4-oxo-4H-chromen-7-ylrutosid [IUPAC], AN-873, CD0174, MFCD00009772, s2292, AKOS015969767, Tox21_111392_1, BCP9000612, CCG-208570, DB08995, MCULE-3603671410, MCULE-6096209142, KS-00000X68, SMP1_000183, NCGC00344564-01, 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-((6-O-alpha-L-rhamnopyranosyl-beta-D-glycopyranosyl)oxy)-4-chromenon, AS-13224, BP-12422, CC-27082, H654, SC-17745, SMR000718616, BCP0726000067, AB0006700, LS-193056, FT-0603441, C10039, D07858, J10091, 520D274, C-23334, 3',5,7-trihydroxy-4'-methoxy flavone-7-rutinoside, SR-01000799147-4, SR-01000799147-5, SR-01000799147-6, Diosmin, European Pharmacopoeia (EP) Reference Standard, Diosmin, United States Pharmacopeia (USP) Reference Standard, Diosmin for system suitability, European Pharmacopoeia (EP) Reference Standard, 28680-33-3, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)methyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(O6-alpha-L-rhamnopyranosyl-beta-D-glucopyranosyloxy)chromen-4-one, 7-((6-O-(6-Deoxy-ga-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, 9000-18-4

ID: 786

InChIKey: GZYFIMLSHBLMKF-UHFFFAOYSA-N
SMILES: C(C(C(=O)O)N)NC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 348153
synonyms found at PubChem are:
ALBIZZIINE, 2-amino-3-(carbamoylamino)propanoic acid, NSC407273, Albizzine, 585-23-9, L-Albizzinine, Propionic acid, 2-amino-3-ureido-, L-AMINO-NEIDOPROPIONIC ACID, Spectrum_000987, SpecPlus_000491, Spectrum2_000459, Spectrum3_001106, Spectrum4_001937, Spectrum5_000851, AC1L88XJ, BSPBio_002812, KBioGR_002315, KBioSS_001467, DivK1c_006587, SCHEMBL439790, SPBio_000538, CHEMBL1330613, 2-amino-3-ureido-propionic acid, KBio1_001531, KBio2_001467, KBio2_004035, KBio2_006603, KBio3_002032, GZYFIMLSHBLMKF-UHFFFAOYSA-N, L-2-Amino-3-ureido-propanoic acid, Propanoic acid, 2-amino-3-ureido-, CCG-38699, NSC132089, AKOS030589651, NSC-132089, NSC-407273, NCGC00094797-01, NCGC00094797-02, 3-[(Aminocarbonyl)amino]-2-aminopropionic acid, ADC92964-12E5-4021-A5F6-F1A810E7151D

ID: 787

InChIKey: GZYVLKKMMDFCKR-UHFFFAOYSA-M
SMILES: CC(=O)SCC[N+](C)(C)C.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 22411
synonyms found at PubChem are:
Acetylthiocholine chloride, 6050-81-3, EINECS 227-953-7, (2-Mercaptoethyl)trimethylammonium chloride acetate, 2-(Acetylthio)-N,N,N-trimethylethanaminium chloride, 2-Acetylthioethyltrimethylammonium chloride, (2-Acetylthio)-N,N,N-trimethylethanaminum chloride, Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, chloride, AMMONIUM, (2-MERCAPTOETHYL)TRIMETHYL-, CHLORIDE, ACETATE, A-1680, s-Acetylthiocholine chloride, C7H16NOS.Cl, Acetylthiocholinechloride, AC1L2KCQ, MLS001056723, SCHEMBL1276372, CHEMBL1256181, CTK5B1604, HMS2233H15, HMS3260K17, HMS3371D04, Tox21_500058, 7815AF, FCH831858, MFCD00038727, AKOS006230681, CCG-221362, LP00058, NCGC00093572-01, NCGC00260743-01, LS-18622, SMR000326680, DB-053634, TR-020887, EU-0100058, FT-0635956, 2-acetylsulfanylethyl(trimethyl)azanium chloride, 2-acetylsulfanylethyl(trimethyl)azanium,chloride, A 5626, [2-(acetylsulfanyl)ethyl]trimethylazanium chloride, C-50688, SR-01000075669, SR-01000075669-1, I14-19316, Ethanaminium,2-(acetylthio)-N,N,N-trimethyl-, chloride (1:1)

ID: 788

InChIKey: HAAITRDZHUANGT-UHFFFAOYSA-N
SMILES: C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 200103
synonyms found at PubChem are:
Sertaconazole nitrate, 99592-39-9, Dermofix, Zalain, Ertaczo, Sertaconazole (nitrate), Sertaconazole mononitrate, FI 7056, Dermoseptic, Ginedermofix, 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate, Dermovit, Fisderm, Extens, Onabet, SR-05000001439, 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid, Ertaczo (TN), Zalain (TN), 1-(2-((7-Chlorobenzo[b]thiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-[2-[(7-chlorobenzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, NCGC00016966-01, AC1L43NG, CAS-99592-39-9, DSSTox_CID_25529, DSSTox_RID_80932, DSSTox_GSID_45529, MLS002154122, C20H16Cl3N3O4S, SCHEMBL261807, CHEMBL1200725, DTXSID2045529, HY-B0736A, HAAITRDZHUANGT-UHFFFAOYSA-N, MolPort-005-940-278, HMS1571A12, HMS2098A12, HMS2231N14, HMS3372H01, HMS3715A12, 99592-32-2 (Parent), BCP09311, Tox21_110718, AC-739, s3161, AKOS015888158, AKOS015964610, ACN-050915, API0005086, CCG-221045, CS-2960, EBD2218183, AN-15587, AS-14332, K784, LS-78268, SMR001233429, AB0014376, FT-0674558, D08510, 4-dichlorophenyl)ethyl)-1H-imidazole mononitrate, 99592-39-9,99592-32-2(freebase), A846049, I01-0378, SR-05000001439-3, 1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2, 1-(2-((7-chlorobenzo[b]thiophen-3-yl)methylchlorobenzo[b]thiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-[2-[(7-chloranyl-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, 1-[2-[(7-Chloro-1-benzothien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate, 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole,nitric acid, 1-[2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Nitrate, 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate

ID: 789

InChIKey: HADVYIYJLZSYGH-BZNPZCIMSA-N
SMILES: N(CC=C)1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"P Parenti" "M Forcella" "J Désiré" "C Norez" "J Bertrand" "V Cendret" "T Legigan" "I Adachi" "Y Blériot" "A Mingot" "F Becq" "A Kato" "S Thibaudeau"

CID is 56952612
synonyms found at PubChem are:
SCHEMBL366469

ID: 790

InChIKey: HANSYUJEPWNHIM-IVMONYBCSA-N
SMILES: CN1C[C@H](C[C@H]2[C@H]1CC3=CN(C4=CC=CC2=C34)C)NS(=O)(=O)N(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 155746
synonyms found at PubChem are:
Mesulergine hydrochloride, Mesulergine HCl, 72786-12-0, CU 32-085, N-(1,6-Dimethylergolin-8-alpha-yl)-N,N-dimethylsulfamide hydrochloride, N'-((8-alpha)-1,6-Dimethylergolin-8-yl)-N,N-dimethylsulfamide monohydrochloride, Sulfamide, N'-((8-alpha)-1,6-dimethylergolin-8-yl)-N,N-dimethyl-, monohydrochloride, Sulfamide, N'-((8alpha)-1,6-dimethylergolin-8-yl)-N,N-dimethyl-, monohydrochloride, CU-32085, AC1L4EW6, C18H26N4O2S.HCl, CQ 32085 monohydrochloride, CHEMBL2303628, DTXSID40223115, MolPort-023-276-175, 64795-35-3 (Parent), AKOS024456723, CQ-32085, CU-32-085, LS-147709, B6815, N'-[(8-?1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamide hydrochloride, SCHEMBL677489

ID: 791

InChIKey: HAPOVYFOVVWLRS-UHFFFAOYSA-N
SMILES: CCC1(CC(=O)NC1=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3291
synonyms found at PubChem are:
ethosuximide, Zarontin, 77-67-8, Etosuximida, 2-Ethyl-2-methylsuccinimide, Ethosuxide, Ethosuccimide, Ethosuccinimide, Petnidan, Suxinutin, Atysmal, Emeside, Ethymal, Suxilep, Etosuximid, Pentinimid, Peptinimid, Petinimid, Pyknolepsinum, Succimitin, Zaraondan, Capitus, Mesentol, Pemalin, Simatin, Succimal, Suximal, Thetamid, Zarodan, Zarondan, Zartalin, Asamid, Etomal, Pemal, Ronton, Suxin, Aethosuximide, Piknolepsin, Thilopemal, Epileo Petit MAL, 3-Ethyl-3-methylpyrrolidine-2,5-dione, Zarondan-Saft, Ethosuximidum, Simatin(E), 3-Methyl-3-ethylsuccinimide, Aethosuccimidum, Etosuximide, CI-366, 2,5-Pyrrolidinedione, 3-ethyl-3-methyl-, Succinimide, 2-ethyl-2-methyl-, 2-Methyl-2-ethylsuccinimide, Ethosuccimid, Etosuccimide, PM 671, PM-671, Suksilep, Etosuccimide [DCIT], 3-Ethyl-3-methyl-2,5-pyrrolidinedione, 3-Ethyl-3-methylsuccinimide, Aethosuximide [German], CN-10,395, N-Ethyl methylsuccinimide, Ethylmethylsuccimide, 3-Methyl-3-ethylpyrrolidine-2,5-dione, Ethosuximidum [INN-Latin], Etosuximida [INN-Spanish], alpha-Ethyl-alpha-methylsuccinimide, alpha-Methyl-alpha-ethylsuccinimide, C.I. 366, gamma-Methyl-gamma-ethyl-succinimide, H 940, H-490, Cl 366, Pyknole.psi.num, Piknole.psi.n, (+-)-2-Ethyl-2-methylsuccinimide, Zarontin (TN), CN-10395, HSDB 1119, gamma-ethyl-gamma-methyl-succinimide, Ethosuximide [USAN:INN:BAN:JAN], EINECS 201-048-7, CI 366, NSC 64013, 3-Ethyl-3-methylpyrroline-2,5-dione, CHEMBL696, .alpha.-Ethyl-.alpha.-methylsuccinimide, BRN 0117054, 3-ethyl-3-methyl-pyrrolidine-2,5-dione, CHEBI:4887, HAPOVYFOVVWLRS-UHFFFAOYSA-N, NSC64013, NSC-64013, .gamma.-Methyl-.gamma.-ethylsuccinimide, E0746, DSSTox_CID_3019, E 7138, DSSTox_RID_76832, DSSTox_GSID_23019, 2,5-Pyrrolidinedione, 3-ethyl-3-methyl-, (+-)-, Etosuximida Faes, Faes, Etosuximida, SR-01000075863, Ethosuximid, CAS-77-67-8, NCGC00016320-01, Prestwick_611, Ethosuximide [USAN:USP:INN:BAN:JAN], Spectrum_001385, AC1L1FLN, AC1Q2SOO, Prestwick0_000165, Prestwick1_000165, Prestwick2_000165, Prestwick3_000165, Spectrum2_001483, Spectrum3_000944, Spectrum4_001051, Spectrum5_001073, (.+/-.)-Ethosuximide, LAB Brand of Ethosuximide, 2, 3-ethyl-3-methyl-, D0Q4XQ, Faes Brand of Ethosuximide, NCIOpen2_000014, Pfizer Brand of Ethosuximide, Lopac0_000532, SCHEMBL34212, BSPBio_000029, KBioGR_001342, KBioSS_001865, 5-21-09-00595 (Beilstein Handbook Reference), Desitin Brand of Ethosuximide, Katwijk Brand of Ethosuximide, DivK1c_000218, SPECTRUM1502196, SPBio_001465, SPBio_001950, BPBio1_000033, GTPL7182, Jenapharm Brand of Ethosuximide, WLN: T5VMVTJ D2 D1, DTXSID7023019, Fortbenton Brand of Ethosuximide, CTK8B3160, Ethosuximide (JP15/USP/INN), Ethosuximide (JP17/USP/INN), Ethosuximide, analytical standard, HMS500K20, KBio1_000218, KBio2_001865, KBio2_004433, KBio2_007001, KBio3_002008, AOB5337, Wernigerode Brand of Ethosuximide, MolPort-003-666-417, NINDS_000218, Parke Davis Brand of Ethosuximide, United Drug Brand of Ethosuximide, gamma-Methyl-gamma-ethylsuccinimide, HMS1568B11, HMS1921L14, HMS2092D20, HMS2095B11, HMS3261L05, HMS3712B11, Pharmakon1600-01502196, HY-B1378, Ethosuximide 1.0 mg/ml in Methanol, Tox21_110370, Tox21_500532, (+/-)-2-ethyl-2-methylsuccinimide, ANW-41860, BDBM50240424, CCG-39217, MFCD00072123, NSC758192, s4626, Warner Lambert Brand of Ethosuximide, Warner-Lambert Brand of Ethosuximide, 3-ethyl-3-methylazolidine-2,5-dione, AKOS005261742, Tox21_110370_1, CS-7976, DB00593, LP00532, MCULE-4034034545, NE54559, NSC-758192, .alpha.-Methyl-.alpha.-ethylsuccinimide, IDI1_000218, 3-Ethyl-3-methyl-2, 5-pyrrolidinedion, NCGC00015418-02, NCGC00015418-03, NCGC00015418-04, NCGC00015418-05, NCGC00015418-06, NCGC00015418-08, NCGC00015418-09, NCGC00093923-01, NCGC00093923-02, NCGC00093923-03, NCGC00093923-04, NCGC00261217-01, 3-Ethyl-3-methyl-2, 5-pyrrolidinedione, AN-23917, AS-16859, SC-65415, SBI-0050515.P003, 2, 5-Pyrrolidinedione, 3-ethyl-3-methyl-, LS-147585, AB00052288, EU-0100532, FT-0668060, ST51037248, C07505, D00539, AB00052288_04, zarontin3-Ethyl-3-methyl-pyrrolidine-2,5-dione, SR-01000075863-1, SR-01000075863-3, SR-01000075863-5, W-109273, 3-Ethyl-3-methyl-pyrrolidine-2,5-dione(Ethosuximide), BRD-A99633051-001-04-7, BRD-A99633051-001-05-4, 3-Ethyl-3-methyl-pyrrolidine-2,5-dione (ethosuximide), Z2379802739, 3-ethyl-5-hydroxy-3-methyl-3,4-dihydro-2H-pyrrol-2-one, 4-ethyl-5-hydroxy-4-methyl-3,4-dihydro-2H-pyrrol-2-one, Ethosuximide, European Pharmacopoeia (EP) Reference Standard, Ethosuximide, United States Pharmacopeia (USP) Reference Standard, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-(2-methyl-1,3,4-oxadiazole-5-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

ID: 792

InChIKey: HAUGRYOERYOXHX-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)N=C3C(=N2)NC(=O)NC3=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 99253
synonyms found at PubChem are:
Alloxazine, Isoalloxazine, 490-59-5, Alloxazin, benzo[g]pteridine-2,4(1H,3H)-dione, 1H-Benzo[g]pteridine-2,4-dione, Benzo(g)pteridine-2,4(1H,3H)-dione, CHEMBL68500, CHEBI:37325, HAUGRYOERYOXHX-UHFFFAOYSA-N, Benzo[g]pteridine-2,4[1H,3H]-dione, benzo[g]pteridine-2,4(3H,10H)-dione, Benzo[g]pteridine-2,3H)-dione, WLN: T C666 BN DMVMV INJ, 1,3-dihydrobenzo[g]pteridine-2,4-dione, SR-01000075199, Alloxazine, 96%, EINECS 207-714-3, NSC 203056, AC1NSYUA, Lopac-A-242, ChemDiv1_028241, 1,2,3,4-Tetrahydrobenzopteridine-2,4-dione, D0Y5TL, MixCom6_000433, UNII-880W3VF9YW, Lopac0_000158, Oprea1_036578, Oprea1_154895, SCHEMBL57289, GTPL456, MLS001060797, 880W3VF9YW, Oi inverted question mark(c)eA, BDBM82038, CHEBI:37327, cid_5372720, CTK1D5851, HMS667D15, DTXSID50197656, MolPort-000-873-349, MolPort-001-002-013, MolPort-006-809-496, HMS1619A05, HMS2229H03, HMS3260O18, 10H-benzo[g]pteridine-2,4-dione, Tox21_500158, ACM490595, MFCD00005020, NSC_99253, NSC203056, NSC402746, SBB071642, ZINC18804836, AKOS000291481, AKOS000659671, API0006552, CCG-204253, LP00158, MCULE-8469415125, NSC-203056, NSC-402746, NCGC00015021-01, NCGC00015021-02, NCGC00015021-03, NCGC00015021-04, NCGC00015021-05, NCGC00093646-01, NCGC00093646-02, NCGC00093646-03, NCGC00260843-01, BAS 00780435, CAS_490-59-5, CC-23863, SMR000282594, ST003008, 1H,2H,3H,4H-benzo[g]pteridine-2,4-dione, A-242, EU-0100158, FT-0718110, C-11327, L000103, 2,3,4,10-tetrahydro-benzo[g]pteridine-2,4-dione, SR-01000075199-1, SR-01000075199-5, BRD-K40213712-001-08-8, Z56790788

ID: 793

InChIKey: HAVWRBANWNTOJX-UHFFFAOYSA-N
SMILES: COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5273569
synonyms found at PubChem are:
Fraxetin, 574-84-5, 7,8-Dihydroxy-6-methoxycoumarin, 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one, 7,8-dihydroxy-6-methoxychromen-2-one, UNII-CD3GD44O3K, 2H-1-Benzopyran-2-one, 7,8-dihydroxy-6-methoxy-, 7,8-Dihydroxy-6-methoxy-2-benzopyrone, CD3GD44O3K, 7,8-Dihydroxy-6-methoxy-chromen-2-one, CHEMBL54909, CHEBI:5169, Q-100662, EINECS 209-376-2, Spectrum_001507, SpecPlus_000477, AC1NRV6E, Spectrum2_001639, Spectrum3_001842, Spectrum4_001686, Spectrum5_000332, AC1Q4F2E, Oprea1_735469, SCHEMBL43472, BSPBio_003224, Fraxetin, analytical standard, KBioGR_001952, KBioSS_001987, MLS002207123, DivK1c_006573, SPECTRUM1504069, SPBio_001737, MEGxp0_000506, ACon0_001071, ACon1_000442, CTK8E5461, KBio1_001517, KBio2_001987, KBio2_004555, KBio2_007123, KBio3_002724, DTXSID00205992, HAVWRBANWNTOJX-UHFFFAOYSA-N, MolPort-001-683-945, KUC106681N, ZINC113309, TNP00177, Coumarin, 7,8-dihydroxy-6-methoxy, BDBM50206215, CCG-38759, Coumarin, 7,8-dihydroxy-6-methoxy-, AKOS000277991, MCULE-2693568829, 7,8-Dihydroxy-6-methoxycoumarin, 98%, NCGC00017270-01, NCGC00017270-02, NCGC00017270-03, NCGC00017270-04, NCGC00017270-05, NCGC00096046-01, NCGC00096046-02, NCGC00169075-01, NCGC00169075-02, 4CN-1003, AJ-11417, AK114503, AN-46013, CC-23048, SC-65962, SMR000112323, ST024715, ZB003792, KSC-11-207-12, AX8110148, DB-050316, KB-249406, TR-020064, FT-0632418, N1765, ST24045548, V1540, 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one #, C09265, 574F845, C-30832, SR-05000002449, SR-05000002449-1, BRD-K76587808-001-03-8, I14-19210, InChI=1/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H

ID: 794

InChIKey: HAWPXGHAZFHHAD-UHFFFAOYSA-N
SMILES: CN(CCCl)CCCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4033
synonyms found at PubChem are:
mechlorethamine, Chlormethine, Nitrogen mustard, Chlorethazine, Mustine, Mustargen, Caryolysine, Cloramin, Embichin, Mecloretamina, 51-75-2, Bis(2-chloroethyl)methylamine, Mechloroethamine, Dichlor amine, 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, 2,2'-Dichloro-N-methyldiethylamine, Nitrogranulogen, Dichloren, Antimit, N-Methyl-bis(2-chloroethyl)amine, Methylbis(2-chloroethyl)amine, N-Methyl lost, N-Methyl-lost, Bis(beta-chloroethyl)methylamine, Methylbis(beta-chloroethyl)amine, Clormetina, Mustine note, Di(2-chloroethyl)methylamine, Methyldi(2-chloroethyl)amine, beta,beta'-Dichlorodiethyl-N-methylamine, N,N-Bis(2-chloroethyl)methylamine, Stickstofflost (ebewe), N-Methyl-bis(beta-chloroethyl)amine, Mecloretamina [Italian], N,N-Di(chloroethyl)methylamine, HN-2, N-Methyl-lost [German], Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, N-Lost, Clormetina [INN-Spanish], Nitrogen mustard (HN-2), 2,2'-Dichlorodiethyl-methylamine, NSC 762, Chlormethinum [INN-Latin], N-Methyl-bis-chloraethylamin, N-Methyl-2,2'-dichlorodiethylamine, ENT-25294, TL 146, Carolysine, Caryolysin, Mebichloramine, Embechine, Mutagen, HN2, Mechlorethanamine, Chloramine (the nitrogen mustard), Chlormethine [INN:BAN], Me chloroethamine, UNII-50D9XSG0VR, MBA, CCRIS 447, N-Methyl-bis-chloraethylamin [German], T-1024, Chlormethine (INN), Diethylamine, 2,2'-dichloro-N-methyl-, CHEBI:28925, HSDB 5083, EINECS 200-120-5, Nitol (*Hydrochloride*), T 1024, Mitoxine (*Hydrochloride*), BRN 0605323, 50D9XSG0VR, N-METHYL-DI(2-CHLORO)-ETHYLAMINE, Bis-(2-chloroethyl)methylamine, bis(2-chloroethyl)(methyl)amine, Bis(beta-chloroethyl) methylamine, Stickstofflost (*Hydrochloride*), HAWPXGHAZFHHAD-UHFFFAOYSA-N, C5H11Cl2N, N,N-Bis(2-chloroethyl)-N-methylamine, NSC-762, Mustargen (TN), .Beta.,.beta.'-Dichlorodiethyl-N-methylamine, 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine, AB00052033_05, Valchlor, Methylchlorethamine, thyldiethylamine, SR-05000001664, Eraso (Salt/Mix), Nitol (Salt/Mix), Hn2 (amine), Embichin (Salt/Mix), Dichloren (Salt/Mix), Chlormethinehydrochloride, Spectrum_000889, Caryolysin (Salt/Mix), Caryolysine (Salt/Mix), 2,2'-Dichloro-N-me, Spectrum2_000448, Spectrum3_000484, Spectrum4_000924, Spectrum5_001702, bis(chloroethyl)methylamine, CHEMBL427, D03SSE, Epitope ID:116224, AC1L1H9H, cid_4033, SCHEMBL3861, Bis(b-chloroethyl)methylamine, BSPBio_001947, KBioGR_001448, KBioSS_001369, DivK1c_000759, SPECTRUM1500375, SPBio_000496, Methyl-bis(2-chloroethyl)amine, GTPL7218, N-methylbis(2-chloroethyl)amine, DTXSID2020975, HMS502F21, KBio1_000759, KBio2_001369, KBio2_003937, KBio2_006505, KBio3_001447, N-methyldi-(2-chloroethyl)amine, 126-85-2 (N-oxide), bis(2-chloro-ethyl)-methyl-amine, bis-(2-chloro-ethyl)-methylamine, NINDS_000759, BDBM200297, Bis(.beta.-chloroethyl)methylamine, HMS1920J15, HMS2091B04, Methylbis(.beta.-chloroethyl)amine, Pharmakon1600-01500375, bis-(2-chloro-ethyl)-methyl-amine, ZINC2539484, CCG-39885, IBS-L0033631, NSC757087, STL484282, 55-86-7 (HYDROCHLORIDE), AKOS006229862, N-Methyl-bis(.beta.-chloroethyl)amine, DB00888, LS-7559, MCULE-6341452542, NSC-757087, 302-70-5 (N-oxide, hydrochloride), IDI1_000759, NCGC00091835-02, NCGC00091835-03, NCGC00091835-04, NCGC00091835-05, NCGC00091835-06, NCGC00091835-07, NCGC00091835-08, NCGC00091835-09, AN-41618, N,N-Bis(2-chloroethyl)-N-methylamine #, NCI60_041682, U601, SBI-0051432.P003, A8064, C07115, D07671, 13159-EP2277876A1, 13159-EP2292614A1, 13159-EP2295426A1, 13159-EP2295427A1, 13159-EP2308833A2, 13159-EP2308861A1, 13159-EP2311825A1, 13159-EP2311842A2, 13159-EP2316834A1, 13159-EP2374454A1, 49304-EP2272827A1, 49304-EP2311840A1, AB00052033-04, 055M867, 1, 5-Dichloro-3-methyl-3-azapentane hydrochloride, I14-8708, SR-05000001664-1, BRD-K12829205-001-03-0

ID: 795

InChIKey: HBBVCKCCQCQCTJ-UHFFFAOYSA-N
SMILES: CCCC1=C(C=CC(=C1O)C(=O)C)OCCCOC2=CC=C(C=C2)OCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603901
synonyms found at PubChem are:
79558-09-1, L-165041, L-165,041, 2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid, L165041, L 165041, 2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-propoxy)phenoxy)acetic acid, CHEMBL153057, HBBVCKCCQCQCTJ-UHFFFAOYSA-N, IN1279, 4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy-acetic acid, 4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxyacetic acid, 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid, {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid, 4-[3-(2-Propyl-3-hydroxy-4-acetyl)phenoxy]propyloxyphenoxy-acetic acid, Aceticacid, 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]-, SR-01000075922, NCGC00015599-01, PubChem19280, Lopac-L-2167, 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid, D0YK9T, AC1O7G4G, DSSTox_CID_20745, DSSTox_RID_79585, DSSTox_GSID_40745, Lopac0_000617, MLS002172459, GTPL2691, QCR-75, SCHEMBL2067483, DTXSID6040745, CHEBI:94812, CTK2I0986, KS-00001DHR, AOB6776, MolPort-003-946-379, HMS2234I08, HMS3261L16, HMS3369O13, BCP06752, ZINC2541693, Tox21_302413, Tox21_500617, ANW-63151, BDBM50085041, BS0108, MFCD04974501, AKOS016004395, API0008434, CCG-204706, CS-0826, DB08078, LP00617, NCGC00015599-02, NCGC00015599-03, NCGC00015599-04, NCGC00015599-05, NCGC00093991-01, NCGC00093991-02, NCGC00093991-03, NCGC00255669-01, NCGC00261302-01, AJ-39208, HY-20019, KB-78064, SC-97563, SMR001254092, AB0033317, AX8135668, CAS-79558-09-1, TC-151896, EU-0100617, X6845, L 2167, L-165,041, >=98% (HPLC), powder, S-7789, SR-01000075922-1, SR-01000075922-4, [4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]aceticacid, {4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propoxy]-phenoxy}-acetic acid(L-165041), 242149-08-2, L41

ID: 796

InChIKey: HBGOLJKPSFNJSD-UHFFFAOYSA-N
SMILES: CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 17506
synonyms found at PubChem are:
Etamsylate, ETHAMSYLATE, 2624-44-4, Cyclonamine, Aglumin, Altodor, Ciclonamina, Dicynene, Dicynone, Eselin, Ciclonamina [Italian], Etamsylatum [INN-Latin], Etamsilato [INN-Spanish], UNII-24YL531VOH, Ethamsylate [USAN], EINECS 220-090-7, MD 141, 24YL531VOH, Diethylammonium 2,5-dihydroxybenzenesulfonate, E 141, Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1), Diethylammonium cyclohexadien-4-ol-1-one-4-sulfonate, Ethamsylate (USAN), Diidroxi-1,4-benzenesulfonato-3-di-etilammonium [Italian], NCGC00017041-01, diethylamine 2,5-dihydroxybenzenesulfonate, 2,5-Dihydroxybenzenesulfonic acid compd. with N-ethylethanamine, CAS-2624-44-4, 2,5-Dihydroxybenzenesulfonic acid compound with diethylamine (1:1), 1-Hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonic acid compd. with diethylamine, 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine, W-107184, Etamsilato, Etamsylatum, Benzenesulfonic acid, 2,5-dihydroxy-, compd. with diethylamine, Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine(1:1), 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1), Ethamsylate [USAN:BAN], C6H6O5S.C4H11N, Etamsylate,(S), Etamsylate [INN], Etamsylate (JAN/INN), D0YF3X, AC1L2A4K, Diidroxi-1,4-benzenesulfonato-3-di-etilammonium, DSSTox_CID_25559, DSSTox_RID_80956, DSSTox_GSID_45559, SCHEMBL34303, ARONIS24284, CHEMBL1514715, DTXSID4045559, CHEBI:31563, KS-00000XOJ, BBC/440, HBGOLJKPSFNJSD-UHFFFAOYSA-N, MolPort-005-942-313, HMS1571K11, HMS2098K11, HMS3652I22, HMS3715K11, BCP12254, HY-B1074, ZX-AS004644, Tox21_110752, MD-141, s4152, SBB080730, AKOS005267176, API0010515, CCG-221015, CS-4630, KS-1169, NCGC00017041-02, NCGC00017041-04, H820, LS-31878, SC-80648, diethylamine 2,5-dihydroxy benzene sulfonate, E-141, E1145, FT-0668047, 2,5-dihydroxybenzenesulfonic acid, diethylamine, 2,5-dihydroxybenzenesulfonic acid; diethylamine, D01282, 624E444, SR-01000838306, 2,5-dihydroxybenzenesulfonic acid; N-ethylethanamine, SR-01000838306-2, 2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine, I01-13242, 2,5-dihydroxybenzenesulfonicacidcompdwithn-ethylethanamine, 2,5-Dihydroxybenzenesulfonic acidN-ethylethanamine (1:1), 2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine, 2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1), 1-hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonicacidcompd.withdiethylamine, diethylammonium 1,4-dihydroxy-3-benzene-sulfonate

ID: 797

InChIKey: HBLCYSFLYMHCBM-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2735333
synonyms found at PubChem are:
AC1MC32V, 2-(isoquinolin-2-ium-5-ylsulfonylamino)ethylazanium dichloride, H-9 dihydrochloride, 116700-36-8, H-9, Dihydrochloride, N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride, IN1299, N-(2-Aminoethyl)isoquinoline-5-sulphonamide dihydrochloride, N-(2-Aminoethyl)-5-isoquinolinesulfonamide, 2HCl, N-(2-aminoethyl)isoquinoline-5-sulfonamide dihydrochloride, SR-01000075503, EU-0100151, BMK1-B5, C11H13N3O2S.2HCl, SCHEMBL1165673, CHEMBL1515334, CTK7E9089, KS-00002WSX, MolPort-001-756-824, 1783AH, BS0094, AKOS015994578, ES-0055, NCGC00093641-01, KB-203219, RT-013182, FT-0661810, A 7795, N-(2-Aminoethyl)-5-isoquinolinesulfonamide 2HCl, SR-01000075503-1, SR-01000075503-3, n-(2-aminoethyl)-5-isoquinolinesulphonamide dihydrochloride

ID: 798

InChIKey: HBLPYIOKPJVFQW-UHFFFAOYSA-N
SMILES: CCN1CCC2=C(CC1)OC(=N2)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 169743
synonyms found at PubChem are:
B-HT 933 dihydrochloride, Azepexole hydrochloride, Azepexole dihydrochloride, 36067-72-8, UNII-O596V52O42, B-HT 933, NSC 310831, O596V52O42, NCGC00093658-01, 2-Amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo(5,4-d)azepine dihydrochloride, 5,6,7,8-Tetrahydro-6-ethyl-4H-oxazolo(4,5-d)azepin-2-amine dihydrochloride, 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride, DSSTox_CID_25756, DSSTox_RID_81099, DSSTox_GSID_45756, Azepexole HCl, 4H-Oxazolo(4,5-d)azepin-2-amine, 5,6,7,8-tetrahydro-6-ethyl-, dihydrochloride, BHT-933, CAS-36067-72-8, AC1Q3AOH, C9H15N3O.2HCl, B-HT 933, dihydrochloride, AC1L54C3, CHEMBL1335356, DTXSID5045756, SCHEMBL10434847, MolPort-003-940-413, 36067-73-9 (Parent), Tox21_111214, Tox21_500177, MFCD01529923, AKOS022488641, Tox21_111214_1, CCG-221481, LP00177, ACM36067728, NCGC00015131-05, NCGC00260862-01, LS-100788, B-161, B7177, EU-0100177, FT-0714343, SR-01000075256, SR-01000075256-1, 2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo-[5,4-d]-azepin-dihydrochloride, 6-ethyl-4,5,7,8-tetrahydro-[1,3]oxazolo[4,5-d]azepin-2-amine dihydrochloride

ID: 799

InChIKey: HBMCQTHGYMTCOF-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=C(C=C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 96009
synonyms found at PubChem are:
4-Acetoxyphenol, 4-Hydroxyphenyl acetate, 3233-32-7, hydroquinone monoacetate, UNII-6GIM3882KV, 1,4-Benzenediol, monoacetate, 6GIM3882KV, CHEBI:31128, HBMCQTHGYMTCOF-UHFFFAOYSA-N, W-202325, 4-hydroxyphenylacetat, 4-acetoxy phenol, NSC 47899, Hydroquinone, acetate, Spectrum_000154, AC1L3VKO, Spectrum2_001145, Spectrum3_001311, Spectrum4_001630, Spectrum5_000419, (4-hydroxyphenyl) acetate, Acetic acid 4-hydroxyphenyl, 1,4-Benzenediol,1-acetate, BSPBio_003001, KBioGR_002039, KBioSS_000634, SCHEMBL203149, SPBio_001069, AC1Q61C0, CHEMBL3039093, CTK4G8546, KBio2_000634, KBio2_003202, KBio2_005770, KBio3_002221, DTXSID70186062, MolPort-003-665-684, acetic acid 4-hydroxy-phenyl ester, CS-B0170, KS-000019RG, NSC47899, ZINC1679468, FCH842268, NSC-47899, AKOS006272548, SDCCGMLS-0066554.P001, NCGC00178351-01, AJ-29574, AM803696, AS-54858, KB-71963, AX8228216, C13636, K-7533, BRD-K12607659-001-02-3

ID: 800

InChIKey: HBOMLICNUCNMMY-UHFFFAOYSA-N
SMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5726
synonyms found at PubChem are:
Azidothymidine (AZT), NSC602670, 3'-Azido-3'-deoxythymidine, Azitidin, Zidovudine, AZT, NSC-602670, Thymidine, 8CI,, Trizivir (Salt/Mix), ACMC-209hgl, 3'-Azido-3'-thyMidine, 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1h,3h)-dione, AC1L1L02, AC1Q69F7, CHEMBL178240, SCHEMBL13609910, 1-(4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, component of Combivir (Salt/Mix), HBOMLICNUCNMMY-UHFFFAOYSA-N, MolPort-000-769-318, MolPort-003-844-345, HMS3369K15, HMS3656A20, STL451000, STL454167, ZINC04164448, AKOS015949577, AN-7244, CCG-229922, MCULE-3669241621, RP07247, NCGC00015044-03, NCGC00015044-04, NCGC00015044-05, NCGC00094963-01, NCGC00094963-02, NCI60_004566, A2698M250, I03-0003, 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 1-(3-azido-2,3-dideoxypentofuranosyl)-2-hydroxy-5-methylpyrimidin-4(1H)-one, 1-(3-azido-2,3-dideoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one, 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione

ID: 801

InChIKey: HBOMLICNUCNMMY-XLPZGREQSA-N
SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "D Zhang" "Y Luo" "JW Hanrahan" "R Robert" "KA Teske" "GW Carlile"

CID is 35370
synonyms found at PubChem are:
zidovudine, Azidothymidine, 30516-87-1, Retrovir, 3'-Azido-3'-deoxythymidine, AZT, Zidovudinum, Compound S, Thymidine, 3'-azido-3'-deoxy-, BW A509U, zidovudin, Zidovudinum [Latin], Zidovudina, Aztec, Zidovudina [Spanish], AZT Antiviral, AZT, Antiviral, ZIDOVUDINE [AZT], AZT (Antiviral), BWA509U, Apo-Zidovudine, BW-A 509U, Novo-Azt, Propolis+AZT, azidodeoxythymidine, 3'-Azido-2',3'-Dideoxythymidine, DRG-0004, Retrovir(TM), AZT & Li & EPO, ZDV, UNII-4B9XT59T7S, Retrovir (TN), 3'-Deoxy-3'-azidothymidine, CCRIS 105, Zidovudine EP III, Cpd S, BW-A509U, BWA-509U, Intron A & AZT, Racemic Liposomal AZT, BW-A-509U, HSDB 6515, Liposomal AZT-SN-1, Liposomal AZT-SN-3, Zidovudine+PRO 140, Zidovudine [USAN:INN:BAN:JAN], PC-SOD+AZT, AZT & srCD4, AZT & rIFN.alpha.2, AZT & rsT4, rIFN-beta seron & AZT, 3-Azido-3-deoxythymidine, 3'-Azido-3'-deoxythymidine (AIDS), AZT & EPO, AZT & GM-CSF, AZT & HPA, AZT & sCD4, AZT & SST, CHEMBL129, NSC 602670, AZT & Li & GM-CSF, AZT+PRO 140, Met-SDF-1.beta. & AZT, AZT & Li & IL-1, AZT & Li & IL-6, MLS000028548, 4B9XT59T7S, AZT & IL-1, AZT & IL-2, AZT & IL-6, AZT & Interferon-.alpha.-2, 1-((2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, AZT & Concanavalin A (ConA), AZT & Lymphoblastoid Interferon, AZT & PM-19, CHEBI:10110, Met-SDF-1.beta. & Zidovudine, AZT & rsCD4 & rIFN.alpha.A, HBOMLICNUCNMMY-XLPZGREQSA-N, 3'-azido-3'-deoxythymidine, AZT, DS-4152 & AZT, AZT & Colony-stimulating factor 2, AZT & NP (from PHCA or HSA), K7 [P Ti2 W10 O40], 3′-Azido-3′-deoxythymidine, NCGC00023945-05, AZT & CD4(178)-PE 40, SMR000058351, DSSTox_CID_127, 3'-Azido-3'-deoxythymidine & Erythropoietin, 3'-Azido-3'-deoxythymidine & Sho-Saiko-To, Interferon AD + 3'-azido-3'-deoxythymidine, 3'-Azido-3'-deoxythymidine & Concanavalin A, 3'-Azido-3'-deoxythymidine & Interleukin-1, 3'-Azido-3'-deoxythymidine & Interleukin-2, 3'-Azido-3'-deoxythymidine & Interleukin-6, AZT TRANSPLACENTAL CARCINOGENESIS STUDY, 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione, DSSTox_RID_75386, DSSTox_GSID_20127, Azitidin, 399024-19-2, 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine, 3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin, 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1, 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6, 3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon, SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle), SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle), 3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19, racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle), Antiviral AZT, ZVD, zudovidine, 3' Azido 3' deoxythymidine, Dendrigen, BWA 509U, 4lhm, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione [AZT], 3&prime, Retrovis (TN), 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione, 3' Azido 2',3' Dideoxythymidine, 3''-azido-thymidine, AZT & IFN-alpha, Zidovudine [USAN:USP:INN:BAN:JAN], Zidovudine & IFNL1, Zidovudine & IFNL2, Zidovudine & IFNL3, Zidovudine (Retrovir), Spectrum_001348, AZT & IFN.alpha., Zidovudine & IL-29, Zidovudine & IL-28A, Zidovudine & IL-28B, AC1L1TKL, AC1Q2OEK, AZT & Interleukin 29, Opera_ID_1602, Prestwick3_000333, Spectrum2_000927, Spectrum3_001507, Spectrum4_000332, Spectrum5_001101, 3'azido-3'deoxythymidine, AZT & Interleukin 28A, AZT & Interleukin 28B, D01XYJ, D0UF5H, D0YX5A, 3'-azido3'-deoxythymidine, AZT & IFNL1, AZT & IFNL2, AZT & IFNL3, Antiviral, Shanghai Genomics, AZT & Interferon lambda-1, AZT & Interferon lambda-2, AZT & Interferon lambda-3, 3''-Deoxy-3-azidothymidine, BSPBio_000365, BSPBio_003153, KBioGR_000703, KBioSS_001828, Zidovudine (JAN/USP/INN), microthornmicro feminineEthOUO, MLS001055351, MLS001076358, MLS002153202, MLS002222249, Zidovudine & Interleukin 29, DivK1c_000524, SPECTRUM1502109, 3'-deoxy-3'-azido-thymidine, SPBio_000834, Zidovudine & Interleukin 28A, Zidovudine & Interleukin 28B, AZT & IL-28A, AZT & IL-28B, BPBio1_000403, GTPL4825, Zidovudine (JP17/USP/INN), DTXSID8020127, SCHEMBL14615088, AZT & IL-29, CTCE-0422, CTK4I2082, HMS501K06, KBio1_000524, KBio2_001828, KBio2_004396, KBio2_006964, KBio3_002653, KS-00000WOF, Antiviral, Chemokine Therapeutics, 3''-Azido-3''-deoxy-thymidine, MolPort-002-507-286, NINDS_000524, Zidovudine & Interferon lambda-1, Zidovudine & Interferon lambda-2, Zidovudine & Interferon lambda-3, HMS1921J20, HMS2090G11, HMS2092D06, HMS2096C07, HMS2234K17, HMS3259H17, HMS3713C07, Pharmakon1600-01502109, 1-((2R,4R,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, ZINC3779042, 3''azido-2''3''-dideoxythymidine, Tox21_110062, Tox21_110894, Tox21_202203, Tox21_300578, AEe paragraph signa.o paragraph sign, ANW-26899, BBL033764, BDBM50002692, CCG-39924, CZ0012, MFCD00006536, NSC758185, STK801891, AKOS005622576, AKOS015842610, Tox21_110062_1, 3''-azido-2'',3''-dideoxythymidine, DB00495, Flt3 ligand (viral infection) Shanghai, LS-1159, MCULE-8664408343, NC00666, NSC-758185, IDI1_000524, NCGC00014918-01, NCGC00023945-03, NCGC00023945-04, NCGC00023945-06, NCGC00023945-07, NCGC00023945-08, NCGC00023945-09, NCGC00023945-10, NCGC00023945-12, NCGC00023945-13, NCGC00178237-01, NCGC00178237-02, NCGC00254276-01, NCGC00259752-01, AS-13019, CPD000058351, SAM002548971, SBI-0051731.P002, AB0012841, Immunostimulant (viral infection), Shanghai, FT-0601543, Propolis & Thymidine, 3'-azido-3'-deoxy-, S2579, 3'-Azido-3'deoxythymidine & Interferon-alpha, EN300-52518, 3'-Azido-3'-deoxythymidine, >=98% (HPLC), C07210, D00413, J10271, W-5037, 3'-Azido-3'deoxythymidine & Interferon .alpha., 3'-Azido-3'-deoxythymidine, >=99.0% (HPLC), SR-01000000098, SR-05000001587, J-700147, SR-01000000098-3, SR-05000001587-1, BRD-K72903603-001-04-6, BRD-K72903603-001-14-5, Z1723414428, Zidovudine, European Pharmacopoeia (EP) Reference Standard, 3'-Azido-3'-deoxythymidine & Recombinant Interferon-.alpha.-2, Zidovudine, United States Pharmacopeia (USP) Reference Standard, 3'-Azido-3'-deoxythymidine & CD4-Pseudomonas exotoxin A hybrid, Beta interferon(rIFN-beta seron) & 3'-Azido-3'-deoxythymidine(AZT), Lecithinized superoxide dismutase & Thymidine, 3'-azido-3'-deoxy-, 3'-Azido-2',3'-dideoxythymidine & sCD4(soluble recombinant protein), Sulfated polysaccharide-peptidoglycan DS-4152 & 3'-Azido-3'-deoxythymidine, Thymidine, 3'-azido-3'-deoxy- & PRO 140 (Anti-CCR5 monoclonal antibody), Zidovudine, Pharmaceutical Secondary Standard; Certified Reference Material, (AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, (AZT)1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(AZT), 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 3'-Azido-3'-deoxythymidine & Lithium & Granulocyte-macrophage colony-stimulating factor, 3'-Azido-3'deoxythymidine & Recombinant Soluble CD4 & Recombinant Interferon.alpha.A, 4-(4-Azido-5-hydroxy-tetrahydro-furan-2-yl)-5-methyl-3H-pyrazine-2,6-dione, Met-Stromal Cell-derived Factor-1.beta. (Human) & 3'-Azido-3'-deoxythymidine, 1-((2R,4S,5S)-4-(diazoamino)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-((2R,5S)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-((2S,4R,5R)-4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione, 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (AzddThd, AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione (N3ddThd), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(3''-azido-2'',3''-dideoxythymidine), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(azidothymidine, AZT), 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione(Zidovudine, AZT), 3'-Azido-3'deoxythymidine & Nanoparticles (from human serum albumin or polyhexylcyanoacrylate), 3-((2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)triaz-1-en-2-ium-1-ide, 3-Azido-1,2,3-trideoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-D-erythro- pentofuranuronic acid

ID: 802

InChIKey: HBPDKDSFLXWOAE-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=NN=C(S1)N(C)C(=O)NC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5383
synonyms found at PubChem are:
tebuthiuron, 34014-18-1, Spike, Graslan, Perflan, Brulan, 1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea, Tiurolan, Prefmid, Tebulan, Brush bullet, Spike 80W, Graslan 250 brush bullets, Caswell No. 366AA, UNII-E5OX6GM11E, EL-103, Tebuthiuron [ANSI:BSI:ISO], HSDB 6863, EINECS 251-793-7, 1-(5-(tert-Butyl)-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea, EPA Pesticide Chemical Code 105501, SHA 105501, BRN 0527479, E5OX6GM11E, CHEBI:81745, Urea, N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-N,N'-dimethyl-, 1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-dimethylharnstoff, Urea, 1-(5-(t-butyl)-1,3,4-thiadiazol-2-yl)-1,3-dimethyl-, 1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-dimethylharnstoff [German], DSSTox_CID_4316, N-(5-(1,1-Dimethylethyl)-1,3,4-thiadiazol-2-yl)-N,N'-dimethylurea, N-(5-(1,1-Dimethylaethyl)-1,3,4-thiadiazol-2-yl)-N,N'-dimethylharnstoff, DSSTox_RID_77365, N-(5-(1,1-Dimethylaethyl)-1,3,4-thiadiazol-2-yl)-N,N'-dimethylharnstoff [German], DSSTox_GSID_24316, N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-N,N'-dimethylurea, N-[5-(tert-butyl)(1,3,4-thiadiazol-2-yl)]-N-methyl(methylamino)carboxamide, Urea, N-(5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl)-N,N'-dimethyl-, CAS-34014-18-1, Bushwacker, Perfmid, Preflan, 1-[5-(tert-Butyl)-1,3,4-thiadiazol-2-yl]-1,3-dimethylurea, Herbec, Herbic, Spectrum_001825, SpecPlus_000426, Spectrum2_001881, Spectrum3_000823, Spectrum4_000663, Spectrum5_001958, AC1L1K8E, AC1Q5IB3, SCHEMBL66366, BSPBio_002345, KBioGR_001065, KBioSS_002330, SPECTRUM330031, MLS000079345, DivK1c_006522, SPBio_001782, CHEMBL1457493, DTXSID3024316, CTK6I4392, El 103, KBio1_001466, KBio2_002327, KBio2_004895, KBio2_007463, KBio3_001845, ZINC43452, HBPDKDSFLXWOAE-UHFFFAOYSA-N, MolPort-002-564-625, HMS2451L04, ACT05627, EBD21687, Urea, 1-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethyl-, Tox21_201451, Tox21_300802, CCG-39419, STK537090, Urea, 2-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethyl- (8CI), AKOS005467953, MCULE-3332482204, ACM34014181, Urea, N-(5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl)-N,N'-dimethyl- (9CI), NCGC00020997-01, NCGC00020997-02, NCGC00020997-03, NCGC00020997-04, NCGC00020997-05, NCGC00020997-06, NCGC00020997-07, NCGC00020997-08, NCGC00023459-02, NCGC00023459-03, NCGC00023459-04, NCGC00023459-05, NCGC00254706-01, NCGC00259002-01, AJ-08997, CC-34661, S342, SMR000036753, ST020539, Tebuthiuron 10 microg/mL in Acetonitrile, ZB001325, AX8152494, KB-147549, LS-159283, FT-0630577, C18436, Tebuthiuron, PESTANAL(R), analytical standard, 33381-EP2274983A1, 33381-EP2305655A2, 33381-EP2311815A1, 33381-EP2371823A1, 014T181, C-13116, I14-7261, J-019419, BRD-K34820100-001-02-1, Urea, 2-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethyl-, N-[5-(1,1-Dimethylethyl)-1,3,4-thiadiazol-2-yl]-NN'-dimethylurea, Pesticide2_Tebuthiuron_C9H16N4OS_Urea, N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-N,N'-dimethyl-

ID: 803

InChIKey: HBRUOCZQTGICHR-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC=CC=C3F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 929915
synonyms found at PubChem are:
2-(2-fluorophenyl)-7-methoxy-4H-chromen-4-one, 2-(2-fluorophenyl)-7-methoxychromen-4-one, 637747-70-7, AC1LIEPG, MLS000769895, CHEMBL1539660, MolPort-000-450-875, HMS2794G21, ZINC520853, STK888592, AKOS002181848, MCULE-9754718497, SMR000434628, ST50070858, 2-(2-Fluoro-phenyl)-7-methoxy-chromen-4-one, F3139-0636

ID: 804

InChIKey: HCBIBCJNVBAKAB-UHFFFAOYSA-N
SMILES: CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5795
synonyms found at PubChem are:
PROCAINE HYDROCHLORIDE, 51-05-8, Procaine Hcl, 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride, Gerovital H3, geriocaine, Atoxicocaine, Chlorocaine, Neotonocaine, Aminocaine, Anadolor, Anesthesol, Anestil, Bernocaine, Ethocaine, Eugerase, Herocaine, Irocaine, Juvocaine, Kerocaine, Lactocaine, Naucaine, Neocaine, Novocainum, Omnicain, Paracain, Planocaine, Sevicaine, Syncaine, Topokain, Westocaine, Cetain, Isocaine-heisler, Novocaine hydrochloride, Procaine (hydrochloride), UNII-95URV01IDQ, Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride, EINECS 200-077-2, 4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride, Procaine (Novocaine) HCl, 95URV01IDQ, AI3-02404, CHEBI:8431, p-Aminobenzoyldiethylaminoethanol hydrochloride, Diethylaminoethanol 4-aminobenzoate hydrochloride, 2-diethylaminoethyl 4-aminobenzoate hydrochloride, 2-Diethylaminoethyl p-aminobenzoate hydrochloride, 2-(Diethylamino)ethyl p-aminobenzoate monohydrochloride, 12663-50-2, p-Aminobenzoic acid 2-diethylaminoethyl ester hydrochloride, Novocain (TN), Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, hydrochloride (1:1), DSSTox_CID_24435, DSSTox_RID_80225, DSSTox_GSID_44435, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Rocaine, MLS001304095, Benzoic acid, p-amino-, 2-(diethylamino)ethyl ester, monohydrochloride, 2-(diethylamino)ethyl 4-aminobenzoate, chloride, CAS-51-05-8, SR-01000076096, NCGC00015864-02, SMR000718771, 2-(diethylamino)ethyl 4-aminobenzoate;hydrochloride, Procain HCl, Procaine hydrochloride [USP:JAN], Procaine hydrochloride [USAN:JAN], Prestwick_530, procain hydrochloride, Procaine, hydrochloride, EC 200-077-2, AC1L1L5N, SCHEMBL27720, MLS001336055, MLS001336056, SPECTRUM1500504, CHEMBL1200841, DTXSID1044435, Procaine hydrochloride, >=97%, CTK6E8436, HY-B0546A, HCBIBCJNVBAKAB-UHFFFAOYSA-N, MolPort-000-835-494, HMS1568I03, HMS1920L06, Pharmakon1600-01500504, Procaine hydrochloride (JP17/USP), Tox21_110248, Tox21_302114, Tox21_500966, CCG-39234, MFCD00013000, NSC757280, s4023, SBB001081, AKOS006029122, Tox21_110248_1, BS-4445, CS-2648, KS-5259, LP00966, MCULE-3361980012, NC00527, NE10725, NSC-757280, 51-05-8 (HCl), NCGC00015864-07, NCGC00094267-01, NCGC00094267-02, NCGC00094267-03, NCGC00094267-04, NCGC00094267-05, NCGC00255993-01, NCGC00261651-01, AC-14461, AN-24388, BC207732, CPD000718771, H789, LS-35780, SAM002554920, SC-18557, A<<.eth inverted question mark Oo NIEaNI, AB0013263, AB1009379, A1163, EU-0100966, ST24049039, ST50319805, BIM-0050939.0001, C07894, D00740, J10158, P 9879, 2-Diethylaminoethyl-4-aminobenzoate hydrochloride, SR-01000076096-1, SR-01000076096-6, W-105920, Z256708908, Procaine hydrochloride, VETRANAL(TM), analytical standard, Procaine Hydrochloride 1.0 mg/ml in Acetonitrile (as free base), Procaine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Procaine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 4- degrees +/->>u+/-(1/2)(1/4)xEa-2- paragraph signthornOO degrees +/-OOo yen, Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 138481-13-7, 4-Aminobenzoic acid 2-diethylaminoethyl ester; p-Aminobenzoic acid diethylaminoethyl ester hydrochloride; Novocaine hydrochloride, 41585-82-4, 8023-03-8, paragraph signO degrees +/->>u+/-(1/2)(1/4)xEa paragraph signthornOO degrees +/-OOo yen NIEaNI, MolPort-000-720-495, Alocaine, AKOS015890654, I01-7088, 2-Diethylaminoethyl 4-aminobenzoate hydrochloride, 99% 50g

ID: 805

InChIKey: HCEYJYMNIQHPPK-DXTZDJJUSA-N
SMILES: C[C@@]12CC[C@@H]3[C@]4(C=CC(=O)C([C@@H]4C[C@H]([C@]3([C@@]15[C@H](O5)C(=O)O[C@H]2C6=COC=C6)C)O)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3034112
synonyms found at PubChem are:
Deacetylgedunin, 7-deacetylgedunin, 10314-90-6, CHEBI:67296, 7-Desacetylgedunin, 7-Deacetyl Genudin, NSC 309912, AC1MHWWF, MLS000563459, CHEMBL465423, 7-deacetoxy-7alpha-hydroxygedunin, HMS2219M05, 14,15:21,23-Diepoxy-7-hydroxy-4,4,8-trimethyl-D-homo-24-nor-17-oxachlola-1,20-,22-triene-3,16-dione (5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-, D-Homo-24-nor-17-oxachlola-1,20-,22-triene-3,16-dione, 14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-, (5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-, Oxireno(c)phenanthro(1,2-d)pyran-3,8(3aH,4bH)-dione, 1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a-decahydro-5-hydroxy-4b,7,7,10a,12a-pentamethyl-, (1S-(1alpha,3aalpha,4aS*,4bbeta,5alpha,6aalpha,10abeta,10balpha,12aalpha))-, SMR000232317, SR-01000712180, SR-01000712180-2, (4aR,6R,6aS,6bR,7aS,10R,10aS,12aR,12bR)-10-(furan-3-yl)-6-hydroxy-4,4,6a,10a,12b-pentamethyl-4a,5,6,6a,10,10a,11,12,12a,12b-decahydronaphtho[2,1-f]oxireno[d]isochromene-3,8(4H,7aH)-dione, (5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-14,15:21,23-diepoxy-7-hydroxy-4,4,8-trimethyl-D-homo-24-nor-17-oxachlola-1,20-,22-triene-3,16-dione, 101509-56-2

ID: 806

InChIKey: HCKUBNLZMKAEIN-GSVOUGTGSA-N
SMILES: C1CN(C(=O)[C@@H]1N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6603720
synonyms found at PubChem are:
(R)-(+)-HA-966, 123931-04-4, UNII-2N9Q4C7WMT, 2N9Q4C7WMT, (3R)-3-amino-1-hydroxypyrrolidin-2-one, CHEMBL335231, R(+)-HA-966, R(+)-3-Amino-1-hydroxy-2-pyrrolidinone, (+)-HA966, (+)-HA-966, (R) pound-(+)-3-Amino-1-hydroxypyrrolidin-2-one, Tocris-0281, AC1O7FZX, Lopac-A-9699, Biomol-NT_000196, D08TAN, R(+)-HA-966, solid, BPBio1_001224, GTPL4066, SCHEMBL1897868, MolPort-003-941-595, r-(+)-ha-966, HMS3266E15, ZINC3791818, BDBM50038159, FCH839175, MFCD00078583, AKOS006273851, (R)-HA-966, API0007692, (R)-3-amino-1-hydroxypyrrolidin-2-one, NCGC00015111-01, NCGC00024522-01, NCGC00024522-02, AJ-45625, HA-966, (R)-, (R)-3-Amino-1-hydroxy-pyrrolidin-2-one, R(+)-3-amino-1-hydroxy-pyrrolidin-2-one, 2-Pyrrolidinone,3-amino-1-hydroxy-,(3R)-, B6243, FT-0770580, (R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one, 1-Hydroxy-3-amino-pyrrolidine-2-one, (R)-, 2-Pyrrolidinone, 3-amino-1-hydroxy-, (R)-, 2-Pyrrolidinone, 3-amino-1-hydroxy-, (3R)-, HA-966, (+)-, C-56142, SR-01000597725, J-005000, SR-01000597725-1, UNII-F2JLV9220T component HCKUBNLZMKAEIN-GSVOUGTGSA-N

ID: 807

InChIKey: HCRKCZRJWPKOAR-JTQLQIEISA-N
SMILES: CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 68844
synonyms found at PubChem are:
Brinzolamide, 138890-62-7, Azopt, Birnzolamide, AL-4862, Brinzolamide [USAN], AL 4862, Brinzolamide (BRZ), Azopt (TN), C12H21N3O5S3, UNII-9451Z89515, Brinzolamide (JAN/USP/INN), CHEBI:3176, (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide, (4R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide, (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-e)-1,2-thiazine-6-sulfonamide 1,1-dioxide, AL04862, DSSTox_CID_25531, DSSTox_RID_80934, DSSTox_GSID_45531, (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, (R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-e)-1,2-thiazine-6-sulfonamide, (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, 138890-50-3, 2H-Thieno(3,2-e)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-, BZ1, Q-200751, 9451Z89515, (R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide, 2H-Thieno(3,2-e)-1,2-thiazine-6-sulfonamide,4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-,1,1-dioxide,R, 3znc, NCGC00016979-01, Brinzolamide [USAN:USP:INN:BAN], CAS-138890-62-7, AC1L2AKA, AC1Q6UVB, Prestwick0_000365, Prestwick1_000365, Prestwick2_000365, Prestwick3_000365, D01MUR, Alcon brand of brinzolamide, SCHEMBL24636, Allphar brand of brinzolamide, BSPBio_000489, MLS002153787, BIDD:GT0039, SPBio_002410, BPBio1_000539, GTPL6797, DTXSID6045531, BDBM10885, CTK7B3009, Brinzolamide, >=98% (HPLC), HCRKCZRJWPKOAR-JTQLQIEISA-N, MolPort-005-940-291, HMS1569I11, HMS2096I11, HMS2234K06, HMS3713I11, BCP22330, EBD27046, HY-B0588, ZINC3953037, Tox21_110722, ABP001062, BG0673, MFCD08067749, s3178, AKOS005145708, Tox21_110722_1, AC-5277, API0001760, CCG-220365, CCG-222516, CS-2788, DB01194, RL01683, NCGC00179542-03, 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-, AK174310, AN-11167, AS-35084, BC218956, CC-25206, SMR001233169, AB0012787, LS-173036, AB00513824, B4258, FT-0082471, FT-0602273, AL4862;AL 4862;AL-4862, C07760, D00652, AB00513824_06, C-21387, SR-01000838832, I09-0605, SR-01000838832-2, BRD-K74913225-001-03-3, Brinzolamide, United States Pharmacopeia (USP) Reference Standard, (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1$l;{6},7,2-thieno[3,2-e][1$l;{6},2]thiazine-6-sulfonamide, (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1$l^{6},7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide, (4r)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2h-thieno[3,2-e][1,2]thiazine-6-sulfonamide-1,1-dioxide, (4R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, (4R)-4-ethylamino-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[4,5-e]thiazine-6-sulfonamide, (5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide, (R)- 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, (R)-3,4-Dihydro-4-ethylamino-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide

ID: 808

InChIKey: HCUARRIEZVDMPT-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=C(N2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 72899
synonyms found at PubChem are:
Indole-2-carboxylic acid, 1H-Indole-2-carboxylic acid, 1477-50-5, 2-Carboxyindole, 2-Indolecarboxylic acid, NSC 16598, Indol-2-Carboxylic Acid, 1H-Indolecarboxylic acid, EINECS 216-030-4, Indole-2-carboxylate, 2-INDOLYLFORMIC ACID, CHEMBL278390, 2-INDOLE CARBOXYLIC ACID, HCUARRIEZVDMPT-UHFFFAOYSA-N, MFCD00005611, 1h-indol-2-carbons, carboxyindole, 2-Indolecarboxylate, indolecarboxylic acid, indole carboxylic acid, PubChem1690, 2-carboxy-1H-indole, 2-indolcarboxylic acid, Spectrum_001485, 2-indol carboxylic acid, SpecPlus_000676, 1H-Indole-2-carboxylic, AC1L2IWZ, AC1Q1HKL, Spectrum2_000021, Spectrum3_000943, Spectrum4_001042, Spectrum5_001735, ACMC-1BU3Q, 1H-2-indolecarboxylic acid, 1H-indole-2-carboxylicacid, AC1Q73TK, SCHEMBL1935, 2-Indolecarboxylicacid(Indole-2-carboxylicacid), 1H-indol-2-carboxylic acid, Oprea1_557882, 2-INDOLE FORMIC ACID, KBioGR_001304, KBioSS_001965, KSC170A9B, MLS002207203, DivK1c_006772, SPECTRUM1502082, SPBio_000081, INDOLE-2-CARBOXLIC ACID, Jsp002764, 1H-indole-2-carbonsäure, HCUARRIEZVDMPT-UHFFFAOYSA-, Indole-2-carboxylic acid, 98%, KBio1_001716, KBio2_001965, KBio2_004533, KBio2_007101, KBio3_002006, DTXSID20163782, MolPort-000-139-980, HMS1921H22, ZINC145536, ACN-S002762, ACT06982, BCP00082, CS-M1850, NSC16598, STR02479, INDOLE-1H-2-CARBOXYLIC ACID, ANW-21089, BBL004548, BDBM50004955, CCG-39889, HTS006381, NSC-16598, SBB003953, STK001808, 1H-Indole-2-carboxylic acid (9CI), AKOS000121595, AB00454, AC-3062, CG-0515, MCULE-2072698467, RP02161, RTR-004253, SDCCGMLS-0065971.P001, TRA0068869, KS-000005V7, NCGC00094957-01, NCGC00094957-02, AJ-12530, AN-13377, BR-46085, KB-52654, LS-81439, SC-01199, SMR000112260, SY003715, TL806279, AB0008354, AB1001711, DB-011564, ST2408916, BB 0242376, FT-0627213, FT-0627228, FT-0651889, I0332, ST45028103, 77I505, B-7291, I-2300, AQ-776/40177767, SR-01000392684, I01-2956, SR-01000392684-1, F0451-0610, N-p-Chlorobenzyl-N',N'-dimethyl-N-[2-pyridyl]lethylenediamine, N-p-Chlorobenzyl-N',N'-dimethyl- N-[2-pyridyl]lethylenediamine, 1H-Indole-2-carboxylic acid; compound with 1H-indole-2-carboxylic acid, InChI=1/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12), 137497-03-1, ICB

ID: 809

InChIKey: HCXVJBMSMIARIN-PHZDYDNGSA-N
SMILES: CC[C@H](/C=C/[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5280794
synonyms found at PubChem are:
STIGMASTEROL, Stigmasterin, 83-48-7, beta-Stigmasterol, Stigmasta-5,22-dien-3beta-ol, (24S)-5,22-Stigmastadien-3beta-ol, UNII-99WUK5D0Y8, 99WUK5D0Y8, CHEBI:28824, Stigmasta-5,22E-dien-3beta-ol, Stigmasta-5,22-dien-3-beta-ol, (3beta,22E)-Stigmasta-5,22-dien-3-ol, Stigmasta-5,22-dien-3-ol, (3b,22E)-, Stigmasta-5,22-dien-3-ol, (3beta,22E)-, (3S,8S,9S,10R,13R,14S,17R)-17-[(E,1R,4S)-4-ethyl-1,5-dimethyl-hex-2-enyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, NSC 8095, .beta.-Stigmasterol, .delta.5,22-Stigmastadien-3.beta.-ol, (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, 14-((2E)(4S,1R)-4-ethyl-1,5-dimethylhex-2-enyl)(1S,5S,10S,11S,2R,14R,15R)-2,15 -dimethyltetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol, Stigmasta-5,22-dien-3-ol, 5,22-Stigmastadien-3beta-ol, b-stigmasterol, NSC-8095, D5-Stigmasterol, Delta5-Stigmasterol, 3beta-Hydroxy-24-ethyl-5,22-cholestadiene, AC1NQXLK, Stigmasterol, ~95%, SCHEMBL23999, stigmasta-5,22t-dien-3b-ol, CCRIS 7476, CHEMBL400247, stigmasta-5,22-dien-3-b-ol, HSDB 7683, HCXVJBMSMIARIN-PHZDYDNGSA-N, MolPort-004-956-055, Delta5,22-Stigmastadien-3beta-ol, HY-N0131, ZINC4096712, EINECS 201-482-7, (24S)-5,22-stigmastadien-3b-ol, BDBM50376364, BI4664, LMST01040123, MFCD00003630, SBB012602, 24aFH-stigmasta-5,22t-dien-3b-ol, AKOS022168193, CS-7746, (22E)-stigmasta-5,22-dien-3beta-ol, (24S)-Stigmast-5,22-dien-3beta-ol, (24xH)-stigmasta-5,22t-dien-3b-ol, 24-Ethyl-5,22-cholestadien-3beta-ol, 5,22-Cholestadien-24-ethyl-3beta-ol, Stigmasta-5,22-dien-3beta-ol (8CI), (24aFH)-stigmasta-5,22t-dien-3b-ol, (24x)-ethylcholesta-5,22-dien-3b-ol, NCGC00142599-03, Stigmasta-5,22-dien-3-ol, (3beta)-, (3b,22E)-stigmasta-5,22-dien-3-ol, 24x-24-ethylcholest-5,22-dien-3b-ol, AN-42262, AS-15473, P501, SC-18170, ST069313, 24-Ethyl-5,22-cholestadien-3.beta.-ol, rac-(24xH)-stigmasta-5,22t-dien-3b-ol, Stigmasta-5,22-dien-3-ol,(3b,22E)-, (3.beta.,22E)-Stigmasta-5,22-dien-3-ol, (24S)-24-Ethylcholesta-5,22-dien-3beta-ol, C05442, 157542-EP2277507A1, 157542-EP2286795A1, Q-201746, Stigmasta-5,22-dien-3-ol, (3beta,22E)- (9CI), UNII-3OE0DD1I5J component HCXVJBMSMIARIN-PHZDYDNGSA-N, UNII-D083681CDS component HCXVJBMSMIARIN-PHZDYDNGSA-N, Stigmasterol, certified reference material, 10 mg/mL in chloroform, (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 17-(4-ethyl-1,5-dimethyl-hex-2-enyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

ID: 810

InChIKey: HCZHHEIFKROPDY-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3845
synonyms found at PubChem are:
kynurenic acid, 4-Hydroxyquinoline-2-carboxylic acid, 492-27-3, 13593-94-7, Kynurenate, Quinurenic acid, Transtorine, Kinurenic acid, Kynuronic acid, 4-oxo-1,4-dihydroquinoline-2-carboxylic acid, 4-Hydroxyquinaldic acid, 4-Hydroxy-2-quinolincarboxylic acid, 1,4-Dihydro-4-oxoquinoline-2-carboxylic acid, 2-Quinolinecarboxylic acid, 4-hydroxy-, 4-Hydroxyquinaldinic acid, 4-Hydroxy-2-quinolinecarboxylic acid, Quinaldic acid, 4-hydroxy-, NSC 58973, 4-oxo-1H-quinoline-2-carboxylic acid, UNII-H030S2S85J, KYNA, CCRIS 4428, NSC58973, EINECS 207-751-5, 2-Carboxy-4-hydroxyquinoline, C10H7NO3, CHEMBL299155, CHEBI:18344, HCZHHEIFKROPDY-UHFFFAOYSA-N, H030S2S85J, NSC-58973, 4-Oxo-1,4-dihydro-quinoline-2-carboxylic acid, 4-hydroxyquinoline-2-carboxylate, SR-01000075455, Kynurensaeure, 4-Hydroxyquinaldate, KYA, 4-hydroxy-Quinaldate, 4-Hydroxyquinaldinate, PubChem7255, Spectrum_001116, Tocris-0223, AC1L1GUE, 4-hydroxy-Quinaldic acid, Spectrum2_001342, Spectrum3_001390, Spectrum4_000814, Spectrum5_001318, Lopac-K-3375, Quinurenic acid|Kynurenate, Biomol-NT_000229, bmse000410, D01SHB, Kynurenic acid, >=98%, AC1Q72XZ, Lopac0_000716, Oprea1_032085, SCHEMBL22979, BSPBio_002980, KBioGR_001327, KBioSS_001596, MLS002172436, DivK1c_000309, SPECTRUM1500688, SPBio_001523, BPBio1_001350, GTPL2918, DTXSID8075417, 4-Hydroxy-2-chinolincarbonsaeure, BDBM81975, CTK0H6756, CTK1D7115, HCZHHEIFKROPDY-UHFFFAOYSA-, HMS500P11, KBio1_000309, KBio2_001596, KBio2_004164, KBio2_006732, KBio3_002200, MolPort-000-881-826, MolPort-002-469-388, NINDS_000309, 4-hydroxyquinolinium-2-carboxylate, HMS1736A10, HMS1921C20, HMS2269G22, HMS3262O13, HMS3266C13, ALBB-014130, KS-00000G3H, ZINC8584773, Quinaldic acid, 4-hydroxy- (8CI), Tox21_500716, ANW-45658, ANW-59277, BBL027606, CCG-39280, CH-565, MFCD00006753, PDSP1_000132, PDSP2_000131, s4719, SBB003671, STL294769, STL301826, 2-Quinolinecarboxylicacid, 4-hydroxy-, 4-Hydroxy-quinoline-2-carboxylic acid, AKOS000118368, AKOS000277721, CS-W020664, DB11937, GS-3763, LP00716, MCULE-4310803796, QC-8403, RTR-017779, IDI1_000309, NSC_5280455, SMP1_000172, NCGC00015581-01, NCGC00015581-02, NCGC00015581-03, NCGC00015581-04, NCGC00015581-05, NCGC00015581-06, NCGC00015581-07, NCGC00015581-08, NCGC00015581-09, NCGC00024505-01, NCGC00024505-02, NCGC00024505-03, NCGC00024505-04, NCGC00024505-05, NCGC00024505-06, NCGC00024505-07, NCGC00261401-01, AJ-72562, AN-45278, CAS_492-27-3, KB-53045, SC-20062, SC-50442, SMR000112310, ST036704, ST066912, AB0025093, AB0097231, DB-008408, DB-081634, HY-100806, LS-141641, TR-035381, B6227, BB 0262293, EU-0100716, FT-0618747, FT-0683827, R1152, ST24043960, UX00002048, W6496, EN300-13998, 2-Quinolinecarboxylicacid, 1,4-dihydro-4-oxo-, C01717, K 3375, Z-8492, 2-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-, 593D947, AE-641/00585057, I04-5756, J-006786, SR-01000075455-1, SR-01000075455-3, I14-11091, Z94602408, 4-HYDROXQUINOLINE-2-CARBOXYLIC ACID/KYNURENIC ACID, 6F535706-B297-4930-A3FC-7A2823830118, InChI=1/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)

ID: 811

InChIKey: HCZKYJDFEPMADG-TXEJJXNPSA-N
SMILES: C[C@H](CC1=CC(=C(C=C1)O)O)[C@@H](C)CC2=CC(=C(C=C2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 71398
synonyms found at PubChem are:
Masoprocol, meso-NDGA, Actinex, meso-Nordihydroguaiaretic acid, 27686-84-6, Masoprocolum, Masoprocolum [INN-Latin], CHX 100, CHX-100, Masoprocol [USAN:INN], UNII-7BO8G1BYQU, meso-4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol, 4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol), 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)-, EINECS 248-606-6, 7BO8G1BYQU, Nordihydroguaiaretic acid from Larrea divaricata (creosote bush), CHEMBL313972, erythro-nordihydroguaiaretic acid, CHEBI:73468, Nordihydroguaiaretic acid (meso-form), (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol, meso-2,3-bis(3,4-dihydroxyphenylmethyl)butane, meso-1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane, meso-4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol), C18H22O4, Actinex (TN), meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, meso-beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butan, 4,4'-((2R,3S)-rel-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol), 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, 4-[(2S,3R)-3-[(3,4-dihydroxyphenyl)methyl]-2-methylbutyl]benzene-1,2-diol, Masoprocol (USAN/INN), nordihydroguaiaretic acid (ndga), TNP00263, NCGC00015741-06, Nordihydroguaiaretsaure, N 5023, AC1Q7ACC, Lopac-N-5023, D0S8BG, mesonordihydroguaiaretic acid, SCHEMBL3818, DSSTox_CID_25178, DSSTox_RID_80726, DSSTox_GSID_45178, Lopac0_000877, INSM-18, BIDD:ER0127, AC1L2G35, 1,2-Benzenediol, 4,4'-((2R,3S)-2,3-dimethyl-1,4-butanediyl)bis-, rel-, 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, DTXSID5045178, BDBM22372, Masoprocol (Nordihydroguaiaretic), ZINC12342, 4-[(2r,3s)-3-[(3,4-Dihydroxyphenyl)methyl]-2-Methylbutyl]benzene-1,2-Diol, HMS3262P15, Tox21_110210, Tox21_500877, EMD 55900, AKOS016014015, API0001379, CCG-204959, DB00179, LP00877, NCGC00015741-01, NCGC00015741-02, NCGC00015741-03, NCGC00015741-07, NCGC00094201-01, NCGC00094201-02, NCGC00094201-03, NCGC00094201-04, NCGC00094201-05, NCGC00261562-01, AJ-08347, ZB000699, AX8137243, AX8267578, CAS-27686-84-6, KB-239312, LS-174190, EU-0100877, D04862, Z-3136, 686B846, SR-01000076028, NCGC00015741-06!NORDIHYDROGUAIARETIC ACID, SR-01000076028-1, meso-4,4'-(2,3-Dimethyltetrameth-ylene)dipyrocatechol, 4,4'-[(2R,3S)-2,3-Dimethyl-1,4-butanediyl]biscatechol, 4,4'-((2R,3S)-2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol, 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol, 334707-72-1, 741285-10-9

ID: 812

InChIKey: HDACQVRGBOVJII-JBDAPHQKSA-N
SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2[C@H]3CCC[C@H]3C[C@H]2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5362129
synonyms found at PubChem are:
ramipril, 87333-19-5, Tritace, Altace, Carasel, Ramace, Triatec, Delix, Acovil, Vesdil, Ramiprilum, Cardace, Lostapres, Hytren, Quark, Hoe-498, Ramiprilum [Latin], Pramace, Ramipro, Naprix, HOE 498, Altace (TN), HOE498, Prilace, Hypren, UNII-L35JN3I7SJ, Ramipril [USAN:INN:BAN], Pramace (discontinued), Ramipril (USP/INN), CHEMBL1168, L35JN3I7SJ, Unipril, CHEBI:8774, C23H32N2O5, (2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, 1-ethyl ester, (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure, (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid, DSSTox_CID_3551, DSSTox_RID_77077, DSSTox_GSID_23551, (2S,3aS,6aS)-1-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid, (2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid, [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid, Cyclopenta(b)pyrrole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-, N-(1S-carboethoxy-3-phenylpropyl)-S-alanyl-cis,endo-2-azabicyclo[3.3.0]octane-3S-carboxylic Acid, Zabien, Ramipril (Altace), (2s,3as,6as)-1((s)-n-((s)-1-carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic, (2S,3aS,6aS)-1-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid, (2S,3aS,6aS)-1-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl) octahydrocyclopenta[b]pyrrole-2-carboxylic acid, (2s,3as,6as)-1-((s)-2-((s)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-octahydrocyclopenta[b]p, (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid, (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name), (2s,3as,6as)-1-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b], (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, [2s,3as,6as]-1-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopen, CPD000466386, SMR000466386, SR-05000001908, Ramipril [USAN:USP:INN:BAN], NCGC00016955-01, (2S,3AS,6AS)-1-[(2S)-2-([(2S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YL]AMINO)PROPANOYL]-OCTAHYDROCYCLOPENTA[B]PYRROLE-2-CARBOXYLIC ACID, (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid, Tritace (TN), CAS-87333-19-5, AC1NSFPR, Spectrum_001958, Astra Brand of Ramipril, Promed Brand of Ramipril, Spectrum3_001794, Spectrum4_001269, Spectrum5_001721, Aventis Brand of Ramipril, Hoechst Brand of Ramipril, Monarch Brand of Ramipril, Almirall Brand of Ramipril, D01STB, SCHEMBL16059, BSPBio_003347, KBioGR_001858, KBioSS_002512, AstraZeneca Brand of Ramipril, MLS000759523, MLS001216547, MLS001423965, BIDD:GT0803, SPECTRUM1505214, Ramipro;Tritace;Prilace;Altace, GTPL6339, Ramipril, >=98% (HPLC), DTXSID8023551, Aventis Pharma Brand of Ramipril, CTK8G2889, KBio2_002504, KBio2_005072, KBio2_007640, KBio3_002849, NPD2431, HDACQVRGBOVJII-JBDAPHQKSA-N, MolPort-001-736-571, HMS2051E04, HMS2090L11, HMS2093M10, HMS2231M05, HMS3259J07, HMS3715M16, Pharmakon1600-01505214, (2S,3AS,6AS)-1-((S)-2-((S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YLAMINO)PROPANOYL)-OCTAHYDROCYCLOPENTA[B]PYRROLE-2-CARBOXYLIC ACID, HY-B0279, ZINC3798757, Tox21_110708, BBL033964, BDBM50084681, MFCD00865775, NSC758933, s1793, STK801937, AKOS005622534, Tox21_110708_1, AB07503, AC-1347, CCG-100833, CS-2270, DB00178, KS-1103, MCULE-5386328912, NC00083, NC00627, NE42859, NSC-758933, NCGC00178127-01, NCGC00178127-02, AN-15038, BC205360, LS-58199, SAM001246757, SAM002699899, SC-17348, SBI-0206728.P001, AB0008490, AB2000297, B2208, Ramipro, Tritace, Altace, Prilace, Ramipril, D00421, J90014, 88094-EP2270011A1, 88094-EP2272841A1, 88094-EP2277879A1, 88094-EP2287165A2, 88094-EP2287166A2, 88094-EP2292620A2, 88094-EP2298742A1, 88094-EP2298776A1, 88094-EP2298779A1, 88094-EP2301923A1, 88094-EP2301931A1, 88094-EP2301936A1, 88094-EP2305648A1, AB00698339-07, AB00698339-08, AB00698339_09, AB00698339_10, 333R195, SR-05000001908-1, SR-05000001908-2, Ramipril, British Pharmacopoeia (BP) Reference Standard, Ramipril, European Pharmacopoeia (EP) Reference Standard, Z1946144927, Ramipril, United States Pharmacopeia (USP) Reference Standard, Ramipril, Pharmaceutical Secondary Standard; Certified Reference Material, (2 S ,3 aS ,6 aS )-1[( S )-N-[( S )-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester, (2 S ,3 aS,6 aS)-1[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester, (2S,3AS,6AS)-1((S)-N-((S)-1-CARBOXY-3-PHENYLPROPYL)ALANYL)OCTAHYDROCYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID 1-ETHYL ESTER, (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid, (2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[d]pyrrole-2-carboxylic acid, (2S,3AS,6AS)-1-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-OCTAHYDRO-CYCLOPENTA[B]PYRROLE-2-CARBOXYLIC ACID, 1-[2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid(Ramipril), 126613-39-6, 4-[2-(1-ethoxycarbonyl-3-phenyl-propyl)aminopropanoyl]-4-azabicyclo[3.3.0]octane-3-carboxylic acid, Cyclopenta(b)pyrrole-2-carboxylic acid, 1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-, (2S(1(R*(R*)),2alpha,3abeta,6abeta))-

ID: 813

InChIKey: HDDSHPAODJUKPD-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)SC3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3334
synonyms found at PubChem are:
fenbendazole, 43210-67-9, Panacur, Fenbendazol, Phenbendasol, Fenbendazolum, Safe-Guard, Safe-quard, Methyl 5-(phenylthio)-2-benzimidazolecarbamate, Hoe 881v, 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole, Fenbendazol [INN-Spanish], Fenbendazolum [INN-Latin], methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate, UNII-621BVT9M36, CCRIS 7309, Fenbendazole [USAN:BAN:INN], Fenbendazole (Panacur), EINECS 256-145-7, Fenbendazole (USP/INN), HOE-881v, Methyl (5-(phenylthio)-1H-benzimidazol-2-yl)carbamate, CHEMBL37161, MLS000069723, methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate, 2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester, methyl (6-(phenylthio)-1H-benzo[d]imidazol-2-yl)carbamate, C15H13N3O2S, CHEBI:77092, HOE 881, 621BVT9M36, Carbamic acid, (5-(phenylthio)-1H-benzimidazol-2-yl)-, methyl ester, Carbamic acid, [5-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester, N-[6-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester, NCGC00016855-01, SMR000058217, [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, CAS-43210-67-9, DSSTox_CID_20672, DSSTox_RID_79532, DSSTox_GSID_40672, Methyl [5-(Phenylthio)benzimidazol-2-yl]carbamate, methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate, methyl 5-(phenylthio)-1H-benzo[d]imidazol-2-ylcarbamate, methyl N-(5-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate, [5-(Phenylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester, methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate, Carbamic acid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester, febendazole, Pancacur, Axilur, Worm-A-Rest, Prestwick_213, Fenbendazole [USAN:USP:INN:BAN], Panacur (TN), Spectrum_001254, Fenbendazole, >=98%, Prestwick0_000210, Prestwick1_000210, Prestwick2_000210, Prestwick3_000210, Spectrum2_000040, Spectrum3_000911, Spectrum4_001010, Spectrum5_001359, AC1L1FP5, AC1Q44DT, cid_3334, Panacur [veterinary] (TN), Oprea1_477843, BSPBio_000199, KBioGR_001479, KBioSS_001734, MLS006010049, DivK1c_000257, SCHEMBL166352, SPECTRUM1501016, SPBio_000139, SPBio_002120, BPBio1_000219, HOE-881Y, SCHEMBL8469702, DTXSID0040672, BDBM31047, CTK6J2932, HMS500M19, KBio1_000257, KBio2_001734, KBio2_004302, KBio2_006870, KBio3_001882, HDDSHPAODJUKPD-UHFFFAOYSA-N, MolPort-001-796-215, MolPort-003-666-346, NINDS_000257, HMS1568J21, HMS1921D03, HMS2090G12, HMS2092B11, HMS2095J21, HMS2234P14, HMS3371J16, HMS3656C04, HMS3712J21, Pharmakon1600-01501016, ZINC402911, BCP22258, HY-B0413, Tox21_110649, Tox21_301828, CCG-39631, MFCD00144301, NSC757824, s2468, SBB058152, STK378581, AKOS005448335, AKOS024462438, Tox21_110649_1, AC-8717, AN-7768, CCG-220210, CS-2517, KS-5042, MCULE-9731772039, NSC-757824, TRA0076149, IDI1_000257, KS-00000G97, NCGC00016855-02, NCGC00016855-03, NCGC00016855-04, NCGC00016855-05, NCGC00016855-06, NCGC00016855-07, NCGC00016855-08, NCGC00016855-10, NCGC00016855-11, NCGC00022515-03, NCGC00022515-04, NCGC00022515-05, NCGC00255694-01, BC206447, I011, LS-32702, SC-17699, SMR004701217, ST011977, ZB012997, ZB012998, SBI-0051634.P002, AB0013422, AB1009282, TL8003046, AB00052199, F0812, FT-0630630, ST24047203, C21876, D04140, J10252, AB00052199-13, AB00052199-14, AB00052199_15, AB00052199_16, Fenbendazole, VETRANAL(TM), analytical standard, 210F679, A826225, methyl 5-(phenyl-thio)-2-benzimidazole-carbamate, Methyl 5-phenylthio-1H-benzimidazol-2-ylcarbamate, SR-01000000195, SR-05000001768, methoxy-N-(5-phenylthiobenzimidazol-2-yl)carboxamide, methoxy-N-(6-phenylthiobenzimidazol-2-yl)carboxamide, Q-201109, SR-01000000195-2, SR-05000001768-1, BRD-K51318897-001-04-7, BRD-K51318897-001-07-0, BRD-K56309460-001-03-0, Methyl 5-(phenylsulfanyl)-1H-benzimidazol-2-ylcarbamate #, Fenbendazole, European Pharmacopoeia (EP) Reference Standard, (5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester, Fenbendazole, United States Pharmacopeia (USP) Reference Standard, methyl N-[5-(phenylsulfanyl)-3H-1,3-benzodiazol-2-yl]carbamate, Fenbendazole, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 814

InChIKey: HDFGOPSGAURCEO-UHFFFAOYSA-N
SMILES: CCN1C(=O)C=CC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4362
synonyms found at PubChem are:
N-ethylmaleimide, 128-53-0, ethylmaleimide, 1-Ethyl-1H-pyrrole-2,5-dione, maleimide, N-ethyl-, 1H-pyrrole-2,5-dione, 1-ethyl-, maleic acid N-ethylimide, NEM, USAF B-121, 1-ethylpyrrole-2,5-dione, UNII-O3C74ACM9V, NSC 7638, Maleic Acid-N-Ethylimide, EINECS 204-892-4, BRN 0112448, CHEMBL8211, O3C74ACM9V, AI3-50085, CHEBI:44485, HDFGOPSGAURCEO-UHFFFAOYSA-N, 25668-22-8, NEQ, N-ethyl maleimide, AC1L1HZS, N-EM, Lopac-E-3876, ACMC-209bf8, D02ZQH, 1-ethylazoline-2,5-dione, WLN: T5VNVJ B2, 1H-Pyrrole-2, 1-ethyl-, Lopac0_000492, SCHEMBL19666, KBioGR_002548, KBioSS_002557, 5-21-10-00006 (Beilstein Handbook Reference), Maleimide, N-ethyl- (8CI), GTPL5335, SCHEMBL9359266, DTXSID1059573, N-Ethylmaleimide, 98% 10g, CTK1A6181, KBio2_002548, KBio2_005116, KBio2_007684, KBio3_003026, KS-00000GSO, NSC7638, cMAP_000078, MolPort-000-385-055, Bio1_000439, Bio1_000928, Bio1_001417, HMS3261D05, ZINC901367, 1-Ethyl-1H-Pyrrole-2, 5-dione, 1-ethyl-3-pyrroline-2,5-quinone, EBD21453, NSC-7638, NSC92547, 1-Ethyl-1H-pyrrole-2,5-dione #, Tox21_500492, 7671AF, ANW-19074, BDBM50220832, GEO-01358, HSCI1_000382, MFCD00005509, NSC-92547, PI-149, STK802307, AKOS000249392, AKOS025244114, CCG-204583, DB02967, LP00492, LS41520, MCULE-9216989340, TRA0003746, NCGC00015415-01, NCGC00015415-02, NCGC00015415-03, NCGC00015415-04, NCGC00093895-01, NCGC00093895-02, NCGC00261177-01, AJ-24354, AN-23020, BC600164, KB-58172, ZB015272, 1-ETHYL-1H-PYRROLE-2,5-DIONENEM, DB-041899, LS-136944, TC-107819, TR-004010, 1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione, E0136, EU-0100492, FT-0631750, N-Ethylmaleimide, BioXtra, >=98% (HPLC), ST24037988, ST51037241, C02441, E 3876, E-8100, N-Ethylmaleimide, crystalline, >=98% (HPLC), N-Ethylmaleimide, BioUltra, >=99.0% (HPLC), SR-01000075860, I11-0594, N-Ethylmaleimide, purum p.a., >=99.0% (HPLC), SR-01000075860-1, BRD-K98297262-001-01-1, 4D028806-9A8A-4D25-B355-AEFDEC5AD901, F0001-0396, InChI=1/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H

ID: 815

InChIKey: HDRXZJPWHTXQRI-BHDTVMLSSA-N
SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 62920
synonyms found at PubChem are:
Diltiazem hydrochloride, 33286-22-5, Diltiazem HCl, Herbesser, Dilzene, Lacerol, Masdil, Tildiem, Tiazac, Mono-Tildiem, Bi-Tildiem, Cardizem CD, Cardizem LA, Dilzem, Dilzicardin, (+)-cis-Diltiazem hydrochloride, Altiazem, Anginyl, Angitil, Angizem, Britiazim, Calcicard, Calnurs, Cardiazem, Cirilen, Citizen, Clarute, Corazet, Deltazen, Diladel, Dilatam, Dilatame, Dilcard, Dilgard, Dilicardin, Dilpral, Dilrene, Diltahexal, Diltelan, Diltiasyn, Diltikor, Diltime, Dinisor, Dodexen, Entrydil, Farmabes, Gadoserin, Helsibon, Incoril, Kaltiazen, Levozem, Longazem, Lytelsen, Metazem, Miocardie, Oxycardil, Pazeadin, Pentilzeno, Poltiazem, Presoken, Surazem, Tilazem, Trumsal, Ziruvate, Bruzem, Carzem, Diatal, Dilfar, Dilsal, Diltam, Diltan, Doclis, Dyalac, Etizen, Etyzen, Herben, Kardil, Myonil, Slozen, Tiadil, Tiaves, Ubicor, Zildem, Carex, Coras, Dazil, Dilem, Dilso, Hesor, Tazem, CRD-401, Hart, Iski, Altiazem Retard, Apo-diltiazem, Cardizem Retard, Diltiazem Merck, Diltiazem Stada, Diltiazem Verla, Diltiazem-Mepha, Cardil Retard, Dil-Sonaramia, Diltiazem-Isis, Dilzem Retard, Dinisor Retard, Myonil Retard, Novo-Diltazem, Syn-Diltiazem, Tildiem Retard, Diltiazem Basics, Diltiazem-Cophar, Uni Masdil, WL Diltiazem, Altiazem RR, Cardizem SR, Diltiazem AWD, Diltiazem GNR, Diltiazem MSD, Diltiazem-GRY, Diltiazem Henning, Diltiazem UPSA, Cirilen AP, Tildiem CR, Tildiem LA, Adizem-CD, Cartia XT, Diltan SR, Diltiazem Eu Rho, Dilzem RR, Taztia XT, Viazem SR, Viazem XL, Diltiazem (hydrochloride), Herbesser 60, Tilazem 90, Herbesser 90 SR, Diltiazem chloridrate, Dilatam 120, Tilazem AS 60, Tilazem AS 90, Dilzereal 90 Retard, Herbesser 180 SR, Angiotrofin, Dilthiazem hydrochloride, Iski-90 SR, UNII-OLH94387TE, Diltiazem, Hydrochloride, Diltiazem HCl (Tiazac), EINECS 251-443-3, Dilacor XR Extended Release Capsules, C22H26N2O4S.HCl, RG 83606, MLS000028432, OLH94387TE, (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride, CHEBI:645509, 103532-26-9, SMR000058375, Cardizem (TN), Cartia XT (TN), (+)-5-(2-(Dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester) monohydrochloride, (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride, (2S-cis)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride, 38411-61-9, Dolizem, Anzem, Diacor, Zilden, Diltia XT, Angiotrofin Retard, Dilt-XR, 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-, monohydrochloride, cis-(+)-, 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis-, Dodexen A.P., Presokin A. P., MK-793, Tiazac extended release, SR-01000003042, RG-83606, Milptin, Carzen, Slozem, Cardizem;Tiazac, DOV diltiazem, Uni-Masdil, Cardizem XL, CRD 401, Dodexen A.P, Presokin A. P, [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride, Prestwick_176, acetate hydrochloride, Diltiazem hydrochloride [USAN:JAN], EINECS 253-918-0, Dilacor XR (TN), Opera_ID_79, Diltiazem hydrochloride [USAN:USP:JAN], Dilt-CD (TN), (+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester monohydrochloride, 2-[(2S,3S)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2H)-yl]-N,N-dimethylethanaminium chloride, AC1L1Y1J, AC1Q3C2G, AC1Q3EQ4, CHEMBL1697, Diltiazem Hydrochloride,(S), SCHEMBL15457, MLS001148257, MLS002222179, Jsp006114, RG 83606 HCl, DTXSID8040147, CTK8E8855, SLV-324, VEN-307, HDRXZJPWHTXQRI-BHDTVMLSSA-N, MolPort-003-931-523, HMS1568K10, (2S-trans)-Diltiazem Hydrochloride, ACT02682, BCP13814, Tox21_500327, BNP-32762, Diltiazem hydrochloride (JP17/USP), MFCD00069252, s1865, (2S-?trans)?-diltiazem hydrochloride, AKOS015961992, CCG-220134, CCG-221631, CS-2339, KS-5089, LP00327, NC00558, NE54505, tetrahydrobenzo[b][1,4]thiazepin-3-yl, NCGC00093768-01, NCGC00261012-01, AC-15189, AS-13703, BC208729, cis-(1)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride, CPD000058375, HY-14656, LS-40513, SAM002564204, SC-18679, (2S,3S)-5-(2-(dimethylamino)ethyl)-2, AB2000340, RT-014406, D3662, EU-0100327, FT-0625017, FT-0667217, ST24046586, ST50320016, BIM-0050315.0001, D 2521, D00616, J10138, (+)-cis-Diltiazem hydrochloride, >=99% (HPLC), 286D225, SR-01000075327, J-019130, SR-01000003042-2, SR-01000003042-4, SR-01000075327-1, Diltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base), Diltiazem hydrochloride, European Pharmacopoeia (EP) Reference Standard, Diltiazem hydrochloride, United States Pharmacopeia (USP) Reference Standard, Diltiazem for system suitability, European Pharmacopoeia (EP) Reference Standard, (2S,3S)-(+)-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride, (2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2H,3H-benzo[b]1,4 -thiazaperhydroepin-3-yl acetate, chloride, (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate hydrochloride, Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; hydrochloride, cis-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one hydrochloride, Diltiazem hydrochloride solution, 1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material, Diltiazem HCl(Tiazac), AC1LCW9L, [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate; hydron; chloride, MolPort-000-740-573, MCULE-4757300773

ID: 816

InChIKey: HDSXDWASQCHADG-HNNXBMFYSA-N
SMILES: COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 23890
synonyms found at PubChem are:
Gloriosine, N-Deacetyl-N-formylcolchicine, N-Formyldeacetylcolchicine, 7411-12-3, NSC 403142, N-Deacetyl-N-formyl Colchicine, N-Formyldesacetylcolchicine, COLCHICINE, N-DEACETYL-N-FORMYL-, Formyldescaetylcolchicine, N-, UNII-U02803H7OJ, U02803H7OJ, NSC403142, BRN 2824080, Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide, N-Formyl-Deacetylcolchicine, AC1L2N2A, N-Formyl-N-deacetylcolchicine, CHEMBL85710, N-Formyl-N-deacethylcolchicine, N-Formyl-N-desacetylcolchicine, GTPL7526, SCHEMBL4069971, XD25, DTXSID80225057, ZINC5731907, FORMYLDESACETYLCOLCHICINE, N-, AKOS017343603, CCG-208385, NSC-403142, NCGC00163534-01, NCGC00163534-02, LS-54675, C19981, 4-14-00-00942 (Beilstein Handbook Reference), C-21432, SR-05000002280, SR-05000002280-2, Formamide,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]formamide, N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]formamide, Formamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- (9CI)

ID: 817

InChIKey: HDVAWXXJVMJBAR-VHSXEESVSA-N
SMILES: C1CCN2CCC[C@H]([C@H]2C1)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 91461
synonyms found at PubChem are:
Lupinine, (-)-Lupinine, 486-70-4, ((1R,9aR)-Octahydro-1H-quinolizin-1-yl)methanol, (+/-)-Lupinine, 10248-30-3, UNII-33BAJ73U1F, EINECS 207-638-0, NSC 21723, (1R-trans)-Octahydro-2H-quinolizine-1-methanol, BRN 0080447, Octahydroquinolizine-1-methanol, 33BAJ73U1F, CHEBI:28012, (1R,9aR)-octahydro-2H-quinolizin-1-ylmethanol, ((1R,2R)-6-azabicyclo[4.4.0]dec-2-yl)methan-1-ol, [(1R,9aR)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-yl]methanol, Lupinine DL-form [MI], Lupinine, (+/-)-, 1S-cis-octahydro-2H-quinolizine-1-methanol, Spectrum_001736, SpecPlus_000606, Spectrum2_000499, Spectrum3_001094, Spectrum4_001921, Spectrum5_000773, 2H-Quinolizine-1-methanol, octahydro-, (1R-trans)-, (1R,9AR)-octahydro-2h-quinolizine-1-methanol, AC1L3M4D, AC1Q77QV, (-)-Lupinine, AldrichCPR, BSPBio_002768, KBioGR_002262, KBioSS_002216, 5-21-01-00338 (Beilstein Handbook Reference), DivK1c_006702, SCHEMBL177708, SPECTRUM1504021, SPBio_000397, CHEMBL459397, 2H-Quinolizine-1-methanol, octahydro-, (1R,9aR)-rel-, CTK8C4234, KBio1_001646, KBio2_002216, KBio2_004784, KBio2_007352, KBio3_001988, TOS-BB-0712, BIL3302, DTXSID00197565, HDVAWXXJVMJBAR-VHSXEESVSA-N, MolPort-001-790-881, ZX-AFC001506, 2H-Quinolizine-1-methanol, octahydro-, (1R-trans)-(+/-)-, HMS1922N13, NSC21723, ZERO/001747, ZINC3881368, ANW-71336, BBL012324, CCG-38712, FCH834919, MFCD00213431, NSC-21723, SBB000161, STK050782, AKOS004120072, MCULE-7143977650, MCULE-9153812583, RP02604, SDCCGMLS-0066745.P001, AJ-46628, AN-45239, KB-00107, LS-88204, ST018409, 2H-Quinolizine-1-methanol, (1R-trans)-, AX8042910, RT-000360, Y9202, (trans-Octahydro-1H-quinolizin-1-yl)methanol, (1R,9aR)octahydro-2H-quinolizin-1-ylmethanol, C10773, W-7849, (1R,9aR)-1-(Octahydroquinolizin-1-yl)methanol, (1R,9Ar)-Octahydro-1H-Quinolizin-1-Yl-Methanol, 486L704, (1R,9aR)-1-(octahydro-quinolizin-1-yl)-methanol, J-500002, J-500379, rac-(1R,9aR)-octahydro-2H-quinolizin-1-ylmethanol, BRD-K45978015-001-03-6, UNII-F74RAC8A5Q component HDVAWXXJVMJBAR-VHSXEESVSA-N, 2H-Quinolizine-1-methanol, octahydro-, (1R-trans)- (9CI)

ID: 818

InChIKey: HDWIHXWEUNVBIY-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2315
synonyms found at PubChem are:
BENDROFLUMETHIAZIDE, Bendrofluazide, 73-48-3, Naturetin, Aprinox, Benzhydroflumethiazide, Benzylrodiuran, Berkozide, Centyl, Pluryl, Neo-naclex, Bentride, Bristuric, Bristuron, Flumesil, Niagaril, Plusuril, Poliuron, Sinesalin, Sodiuretic, Thiazidico, Benuron, Intolex, Livesan, Nikion, Orsile, Pluryle, Repicin, Salural, Salures, Urlea, Benzylhydroflumethiazide, Neo-rontyl, Relan beta, BHFT, Bendroflumethiazidum, Corzide, Rauzide, Benzydroflumethiazide, bendrofumethiazide, Bendroflumetiazida, Rautrax N, Naturetin-2.5, Naturine, Bendroflumethazide, Flumersil, Naigaril, Nateretin, Bendroflumethiazidum [INN-Latin], Bendroflumetiazida [INN-Spanish], Benzy-rodiuran, Bendroflumetiazide, NATURETIN-5, NATURETIN-10, Be 724-A, Bendroflumetiazide [DCIT], BL H368, FT 8, Bendroflumethiazide [USP], FT 81, Naturetin (TN), HSDB 3293, C15H14F3N3O4S2, EINECS 200-800-1, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide, BRN 0373316, 3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine, 1,1-dioxide, MLS000028558, CHEBI:3013, Bendroflumethiazide (JAN/USP/INN), 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide, 3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine, 1,1-dioxide, SMR000058802, Bendroflumethiazide-d5, DSSTox_CID_2647, DSSTox_RID_76673, DSSTox_GSID_22647, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-3,4-dihydro-6-(trifluoromethyl)-,1,1-dioxide, 3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, (+-)-3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide, (+-)-, 3-(phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, SR-01000000103, NeoNaClex, Bendroflumethiazid, CAS-73-48-3, benzidroflumetiazide, Relan .beta., NCGC00016312-01, 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Prestwick_992, Behenic Fatty Acids, rac Bendroflumethiazide, Bendroflumethiazide [USP:INN:BAN:JAN], Spectrum_001386, AC1L1DEI, Opera_ID_1043, Prestwick0_000784, Prestwick1_000784, Prestwick2_000784, Prestwick3_000784, Spectrum2_001524, Spectrum3_001558, Spectrum4_000774, Spectrum5_001016, D02PAH, CHEMBL1684, SCHEMBL26016, BSPBio_000888, BSPBio_003036, KBioGR_001188, KBioSS_001866, 4-27-00-08041 (Beilstein Handbook Reference), MLS001076062, MLS002548857, DivK1c_000274, SPECTRUM1503104, SPBio_001308, SPBio_002827, (.+/-.)-Bendroflumethiazide, BPBio1_000978, GTPL7122, DTXSID5022647, CTK8F7951, HMS500N16, KBio1_000274, KBio2_001866, KBio2_004434, KBio2_007002, KBio3_002536, HDWIHXWEUNVBIY-UHFFFAOYSA-N, MolPort-003-666-443, NINDS_000274, HMS1570M10, HMS1922E15, HMS2092J16, HMS2097M10, HMS2230G10, HMS3259D17, HMS3370I20, HMS3714M10, Pharmakon1600-01503104, BCP24525, Tox21_110365, 2259AH, CCG-39302, NSC758229, AKOS024255718, Tox21_110365_1, AN-5774, API0001605, Bendroflumethiazide, analytical standard, DB00436, HS-0095, MCULE-7811865125, NC00664, NSC-758229, IDI1_000274, NCGC00018194-02, NCGC00018194-03, NCGC00018194-04, NCGC00018194-08, NCGC00089729-02, NCGC00089729-03, 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 4CN-1235, CPD000058802, LS-40431, SAM002264598, SBI-0051772.P002, AB00052315, EU-0009291, FT-0662517, ST51014919, UNM000000601501, C07758, D00650, AB00052315_15, AB00052315_16, 073B483, SR-01000000103-2, SR-01000000103-4, BRD-A80017228-001-05-9, BRD-A80017228-001-15-8, Z2786051551, Bendroflumethiazide, British Pharmacopoeia (BP) Reference Standard, Bendroflumethiazide, European Pharmacopoeia (EP) Reference Standard, Bendroflumethiazide, United States Pharmacopeia (USP) Reference Standard, 1,1-dioxo-3-benzyl-6-(trifluoromethyl)-2H,3H,4H-benzo[e]1,2,4-thiadiazine-7-su lfonamide, 3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, (+-)-3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide,3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide, 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide, 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, 3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide #, 3-benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, 96782-79-5

ID: 819

InChIKey: HDZZVAMISRMYHH-KCGFPETGSA-N
SMILES: C1=CN(C2=C1C(=NC=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6245
synonyms found at PubChem are:
tubercidin, 7-Deazaadenosine, 69-33-0, Sparsomycin A, Tubercidine, sparsamycin A, UNII-M351LCX45Y, SKI 26996, 7-Deazadenosine, EINECS 200-703-4, Adenosine, 7-deaza-, Antibiotic 155B2T, BRN 0038498, AI3-52353, CHEMBL267099, M351LCX45Y, Antibiotic XK 101-1, CHEBI:48267, 7H-Pyrrolo(2,3-d)pyrimidine, 4-amino-7-beta-D-ribofuranosyl-, U10071, U-10071, 4-Amino-7-(beta-D-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine, 4-Amino-7-beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine, 4-Amino-7beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine, 7-beta-D-Ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine, 7beta-D-Ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine, 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-beta-D-ribofuranosyl-, 7H-Pyrrolo(2,3-d)pyrimidine, 4-amino-7beta-D-ribofuranosyl-, NSC 56408, 7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-beta-CD-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidin-4-amine, U 10071, B 120121, 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol, (2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, Deazaadenosine, 7-Deaza-rA, 1pr5, D0H6WV, AC1L1M3X, cid_6245, SCHEMBL8259, 4-26-00-01117 (Beilstein Handbook Reference), MLS001074702, BIDD:GT0715, GTPL4755, HDZZVAMISRMYHH-KCGFPETGSA-N, MolPort-004-964-088, HMS2269L05, EX-A1062, KS-00000H8T, ZINC3832269, BDBM50000298, MFCD00056012, AKOS024464517, API0008481, CS-5578, DB03172, tubercidin from streptomyces tubercidicus, NCGC00163638-01, AK163027, SMR000471894, AX8156053, HY-100126, LS-139541, ST24045647, X7273, SR-01000765501, Tubercidin, from Streptomyces tubercidicus, ~95%, SR-01000765501-3, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine,7-b-D-ribofuranosyl-, 4-Amino-7 beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine, 7-beta-D-ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amine, 7-beta-D-ribofuranosyl-7H-pyrrolo-(2,3-d)pyrimidin-4-amine (9CI), (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol, (2R,3R,4S,5R)-2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol, (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, (2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol, 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (Tubercidin), 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol(tubercidin)

ID: 820

InChIKey: HEBKCHPVOIAQTA-NGQZWQHPSA-N
SMILES: C([C@H](C([C@H](CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6912
synonyms found at PubChem are:
xylitol, ribitol, adonitol, D-Xylitol, Xylite, 87-99-0, 488-81-3, Adonit, Adonite, D-ribitol, Xylit, Eutrit, Klinit, Xyliton, Xylite (sugar), Kannit, Newtol, 1,2,3,4,5-pentanepentol, Xylisorb, meso-ribitol, meso-xylitol, L-ribitol, L-xylitol, UNII-353ZQ9TVDA, UNII-VCQ006KQ1E, NSC 25283, (2R,3R,4S)-Pentane-1,2,3,4,5-pentaol, BRN 1720523, CHEBI:15963, CHEBI:17151, (2R,3S,4S)-Pentane-1,2,3,4,5-pentaol, EINECS 201-788-0, 353ZQ9TVDA, VCQ006KQ1E, (2R,4S)-pentane-1,2,3,4,5-pentol, (2R,3s,4S)-pentane-1,2,3,4,5-pentol, HEBKCHPVOIAQTA-ZXFHETKHSA-N, 1,2,3,4,5-Pentahydroxypentane, (2S,4R)-pentane-1,2,3,4,5-pentol, 16277-71-7, 4-01-00-02832 (Beilstein Handbook Reference), C5H12O5, EINECS 207-685-7, NSC 16868, BRN 1720524, WURCS=1.0/1,0/[h111h], WURCS=1.0/1,0/[h121h], Xylitol [USAN], Adonito, Adonitot, Adonitrot, Adonitt, Fluorette, Pentitot, Kylit, xylo-Pentitol, Xylitol [INN:BAN:JAN:NF], D-Adonitol, Xylitol C, HSDB 7967, Xylitab DC, Wood sugar alcohol, RB0, Xylitol,(S), Ribitol (Adonitol), Adonitol (7CI), Xylisorb 300, Xylisorb 700, Xylitab 100, Xylitab 300, Adonitol, >=99%, Xylitol, >=99%, AC1L1NKP, bmse000062, bmse000129, bmse000886, Epitope ID:114702, Epitope ID:114703, EC 201-788-0, AC1Q59QK, SCHEMBL4250, Xylitol, analytical standard, DSSTox_CID_22514, DSSTox_RID_80046, DSSTox_GSID_42514, SCHEMBL15318, 1,2,3,4,5-Pentanot, MLS002695898, 1,2,3,4,5-Pentanepentot, CHEMBL96783, Ribitol (6CI,8CI,9CI), QSPL 191, SCHEMBL1924966, CHEMBL1865120, CHEMBL3137744, DTXSID7042514, HEBKCHPVOIAQTA-NGQZWQHPSA-N, HEBKCHPVOIAQTA-SCDXWVJYSA-N, MolPort-003-895-940, MolPort-003-934-322, MolPort-044-875-282, Ribitol, Adonite, 488-81-3, HY-N0538, Tox21_201056, MFCD00064291, MFCD00064292, s2612, s4546, ZINC18068098, 1,2,3,4,5-PentahydroxypentaneXylite, AKOS015903403, AKOS015915193, ZINC100014205, ZINC100018612, CCG-214167, CS-2987, CS-6043, DB01904, CAS-87-99-0, KS-00000Y00, (2S,4R)pentane-1,2,3,4,5-pentaol, NCGC00165982-01, NCGC00165982-02, NCGC00258609-01, Adonitol, BioXtra, >=99.0% (HPLC), DS-11416, E967, K573, SMR001562099, HY-100582, LS-162656, Xylitol, Vetec(TM) reagent grade, >=99%, A0171, FT-0631414, FT-0656634, N1725, ST50411707, (2R,3r,4S)-pentane-1,2,3,4,5-pentol, (2R,3s,4S)-Pentane-1,2,3,4,5-pentot, 2088-EP2272822A1, 2088-EP2275417A2, 2088-EP2284162A2, 2088-EP2284163A2, 2088-EP2292234A1, 2088-EP2292612A2, 2088-EP2301938A1, 2088-EP2305254A1, 2088-EP2311842A2, 2088-EP2314584A1, 2088-EP2371811A2, 2088-EP2377849A2, Adonitol, BioReagent, suitable for cell culture, C00379, C00474, K-9195, X-7000, 127873-EP2275398A1, 127873-EP2295402A2, 127873-EP2374783A1, 127873-EP2377841A1, I14-7373, I14-19011, I14-19012, Xylitol, European Pharmacopoeia (EP) Reference Standard, UNII-YFV05Y57M9 component HEBKCHPVOIAQTA-SCDXWVJYSA-N, UNII-YFV05Y57M9 component HEBKCHPVOIAQTA-ZXFHETKHSA-N, 5DCF4F57-E023-469A-B4F3-91E8349A6705, Xylitol, United States Pharmacopeia (USP) Reference Standard, 6684F574-C267-40CB-8828-12F2550E58D0, Xylitol, Pharmaceutical Secondary Standard; Certified Reference Material, 12426-00-5, 28296-13-1, 37191-59-6, 7313-55-5, 75398-81-1, 84709-28-4, 84709-42-2, 87849-01-2

ID: 821

InChIKey: HEFIYUQVAZFDEE-MKTPKCENSA-N
SMILES: CC(C)[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@H]5CN([C@@H]6CC7=CNC8=CC=CC(=C78)C6=C5)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 31116
synonyms found at PubChem are:
Ergocristine, Ergocrystine, 511-08-0, UNII-3E58HO2T0U, NSC 93743, MLS000069350, 3E58HO2T0U, CHEBI:4821, SMR000058447, Ergocristin, EINECS 208-120-7, 5'alpha-benzyl-12'-hydroxy-3',6',18-trioxo-2'-(propan-2-yl)ergotaman, BRN 0079046, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'-alpha)-, AC1L1KYS, DEA Code 8612, Lopac0_000514, 4-25-00-00966 (Beilstein Handbook Reference), cid_31116, SCHEMBL177877, CHEMBL446315, BDBM30702, HSDB 8380, ZINC53282743, CCG-204605, NSC93743 0, E-140, EU-0100514, FT-0667952, C09164, SR-01000075383, SR-01000075383-1, 491D4F3D-1B0B-4E0A-8AB0-0C759A3E8E26, UNII-2J09Y26C6I component HEFIYUQVAZFDEE-MKTPKCENSA-N, 2-Hydroxy-2-[1-methylethyl]-5-[phenylmethyl]ergotaman-3,6,18-trione, (5'|A)-12'-Hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)ergotaman-3',6',18-trione, (5'alpha)-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)ergotaman-3',6',18-trione, 12'-Hydroxy-2'-(1-methyl-ethyl)-5'-(phenylmethyl)ergotaman-3'6'18-trione, (6aR,9R)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide, 1080515-62-3, 12 inverted exclamation marka-Hydroxy-2 inverted exclamation marka-(1-methylethyl)-5 inverted exclamation marka-(phenylmethyl)ergotaman-3 inverted exclamation marka,6 inverted exclamation marka,18 inverted exclamation marka-trione, 22973-77-9, 24177-05-7, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'alpha)- (9CI)

ID: 822

InChIKey: HEFNNWSXXWATRW-JTQLQIEISA-N
SMILES: C[C@@H](C1=CC=C(C=C1)CC(C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 39912
synonyms found at PubChem are:
(S)-(+)-Ibuprofen, 51146-56-6, DEXIBUPROFEN, S(+)-Ibuprofen, (S)-2-(4-Isobutylphenyl)propanoic acid, (S)-Ibuprofen, d-Ibuproten, (S)-(+)-2-(4-Isobutylphenyl)propionic acid, (+)-(S)-p-Isobutylhydratropic acid, Seractil, (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid, UNII-671DKG7P5S, S-(+)-ibuprofen, (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid, (2S)-2-(4-isobutylphenyl)propanoic acid, CHEMBL175, 671DKG7P5S, CHEBI:43415, (S)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid, NCGC00016861-05, (S)-2-(4-Isobutylphenyl)propionic acid, (S)-2-(4-isobutyl-phenyl)-propionic acid, CAS-51146-56-6, S-(+)-2-(4-Isobutylphenyl)propionic acid, Dexibuprofene, Dexibuprofeno, Dexibuprofenum, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, (S)-, SMR000326688, Dexibuprofene [INN-French], Dexibuprofenum [INN-Latin], Dexibuprofeno [INN-Spanish], Atriscal, Dolomin, DexOptifen, s-ibuprofen, d-Ibuprofen, Maxibufen Syr, Dexibuprofen [USAN:INN:BAN], Maxibufen ER, (+)-Ibuprophen, (s)(+)ibuprofen, (+)-Ibuprofen, S (+) Ibuprofen, (s)(+) ibuprofen, (+)-(S)-Ibuprofen, Lopac-I-106, Prestwick0_000907, Prestwick1_000907, Prestwick2_000907, Prestwick3_000907, Lopac-I-4883, Dexibuprofen (USAN/INN), AC1L22PX, DSSTox_CID_28650, DSSTox_RID_82920, DSSTox_GSID_48724, Lopac0_000654, SCHEMBL43531, BSPBio_000754, MLS001066327, MLS001335879, MLS001335880, SPBio_002953, BPBio1_000830, ZINC2647, DTXSID9048724, CTK3J6903, HEFNNWSXXWATRW-JTQLQIEISA-N, MolPort-003-931-290, HMS1570F16, HMS2097F16, HMS2231C07, HMS3262C09, HMS3714F16, Pharmakon1600-01502363, Tox21_113141, Tox21_500654, ANW-31200, BDBM50169047, HY-78131A, MFCD00069289, NSC759814, AKOS015890528, AKOS015994628, CCG-204740, CS-1393, DB09213, HS-0088, LP00654, MP-0584, NSC-759814, RTR-018233, (S)-2-(p-Isobutylphenyl)propionic acid, NCGC00015529-01, NCGC00015529-02, NCGC00015529-03, NCGC00015529-11, NCGC00016861-01, NCGC00016861-02, NCGC00016861-03, NCGC00016861-06, NCGC00094017-01, NCGC00094017-02, NCGC00094017-04, NCGC00261339-01, AJ-94574, AN-41344, BR-73124, O942, SC-22749, KB-295413, ST2408283, TR-018233, UNM-0000306099, AB00513957, AM20060649, EU-0100654, FT-0670258, I-106, I0549, (S)-(+)-Ibuprofen, ReagentPlus(R), 99%, (s)-(+)-2-(4-isobutylphenyl) propionic acid, D03715, AB00513957_07, 146I566, SR-01000075945, SR-01000761395, (S)-?-Methyl-4-(2-methylpropyl)benzeneacetic acid, I01-7330, Q-200941, Q-200942, SR-01000075945-1, SR-01000761395-2, BRD-K14965640-001-03-3, (+)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid, Z1741977191, (alphaS)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid, Benzeneacetic acid,|A-methyl-4-(2-methylpropyl)-,(|AS)-, UNII-WK2XYI10QM component HEFNNWSXXWATRW-JTQLQIEISA-N, benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, (alphaS)-, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, (alphaS)- (9CI), (2S)-2-[4-(2-Methylpropyl)phenyl]propionic acid; (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid; (S)-(+)-2-(4-Isobutylphenyl)propionic acid

ID: 823

InChIKey: HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3463
synonyms found at PubChem are:
gemfibrozil, 25812-30-0, Lopid, 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid, Jezil, Decrelip, Lipur, Bolutol, Apo-Gemfibrozil, Gemfibromax, Cholespid, Fibratol, Fibrocit, Gemfibril, Gemlipid, Hipolixan, Lipazil, Litarek, Trialmin, Ausgem, Pilder, Gen-Fibro, Gemfibrozilo, Gemfibrozilum, Gemfibrosil, Ipolipid, Lanaterom, Lifibron, Normolip, Progemzal, Renabrazin, Synbrozil, Taborcil, Brozil, Clearol, Elmogan, Fetinor, Gemnpid, Innogen, Lipigem, Lipira, Lipizyl, Lipozid, Micolip, Polyxit, Reducel, Regulip, Sinelip, Tentroc, Gozid, Hidil, Gemd, WL-Gemfibrozil, 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid, Gevilon Uno, CI-719, Low-Lip, Gem-S, Gevilon, Gemcor, Genlip, Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-, Nu-Gemfibrozil, Novo-Gemfibrozil, Lopid R, Gemfibrozilum [INN-Latin], Gemfibrozilo [INN-Spanish], Innogem, 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure, 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure, CI 719, CCRIS 318, Gemfibrozil (Lopid), Gemfibrozil [USAN:BAN:INN], Lopid (TN), UNII-Q8X02027X3, TEVA-A, EINECS 247-280-2, CHEMBL457, Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-, BRN 1881200, 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid, Gemfibrozil (JAN/USP/INN), MLS000028421, CHEBI:5296, HEMJJKBWTPKOJG-UHFFFAOYSA-N, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid, Q8X02027X3, 5-(2,5-Dimethyl-Phenoxy)-2,2-Dimethyl-Pentanoic Acid, 5-[(2,5-dimethylphenyl)oxy]-2,2-dimethylpentanoic acid, NCGC00016794-09, CPD000058393, SMR000058393, CAS-25812-30-0, DSSTox_CID_652, DSSTox_RID_75712, DSSTox_GSID_20652, W-107216, ApoGemfibrozil, Gemhexal, GenGemfibrozil, NuGemfibrozil, GEMFIBROZIL (SEE ALSO PEROXISOME PROJECT (GEMFIBROZIL)), PEROXISOME PROJECT (GEMFIBROZIL) (SEE ALSO GEMFIBROZIL), Apo Gemfibrozil, Gemfibrozilo Ur, Gen Gemfibrozil, Gen-Gemfibrozil, Nu Gemfibrozil, DBL Gemfibrozil, Lipox Gemfi, Novo Gemfibrozil, PMS Gemfibrozil, PMS-Gemfibrozil, SBPA Gemfibrozil, Gemfibrozilo Bexal, GenRX Gemfibrozil, Gemfi 1A Pharma, Gemfibrozilo Bayvit, Gemfibrozil, SBPA, GFZ, Gemfibrozil, GenRX, Bayvit, Gemfibrozilo, Chem mart Gemfibrozil, Healthsense Gemfibrozil, Gemfibrozil, Healthsense, SR-01000000056, lopizid, Terry White Chemists Gemfibrozil, HSDB 7735, Gemfibrozil,(S), CI719, Gemfibrozil [USAN:USP:INN:BAN], Prestwick_637, dimethylpentanoic acid, Gen-Fibro (TN), Jezil (TN), Spectrum_000825, 1A Brand of Gemfibrozil, AC1L1FZT, Opera_ID_1658, Prestwick0_000214, Prestwick1_000214, Prestwick2_000214, Prestwick3_000214, Spectrum2_001097, Spectrum3_000440, Spectrum4_000562, Spectrum5_000750, Spectrum5_001991, TAD Brand of Gemfibrozil, Bull Brand of Gemfibrozil, Bexal Brand of Gemfibrozil, D05VIX, Hexal Brand of Gemfibrozil, Ipsen Brand of Gemfibrozil, Sigma Brand of Gemfibrozil, AC1Q2JC7, Apotex Brand of Gemfibrozil, Bayvit Brand of Gemfibrozil, Ferrer Brand of Gemfibrozil, Pfizer Brand of Gemfibrozil, SCHEMBL4813, Douglas Brand of Gemfibrozil, BSPBio_000227, BSPBio_002060, KBioGR_000964, KBioSS_001305, Faulding Brand of Gemfibrozil, Gemcor;Jezil;Gen-Fibro;Lopid, Genpharm Brand of Gemfibrozil, Menarini Brand of Gemfibrozil, MLS001055364, MLS006011850, Quimifar Brand of Gemfibrozil, ARONIS24091, DivK1c_000138, SPECTRUM1500313, Biochemie Brand of Gemfibrozil, Cantabria Brand of Gemfibrozil, Novopharm Brand of Gemfibrozil, Nu Pharm Brand of Gemfibrozil, Nu-Pharm Brand of Gemfibrozil, SPBio_001174, SPBio_002148, Chem mart Brand of Gemfibrozil, Alphapharm Brand of Gemfibrozil, BPBio1_000251, GTPL3439, Gemfibrozil, analytical standard, DTXSID0020652, Farmasierra Brand of Gemfibrozil, Healthsense Brand of Gemfibrozil, HMS500G20, KBio1_000138, KBio2_001305, KBio2_003873, KBio2_006441, KBio3_001280, Parke Davis Brand of Gemfibrozil, United Drug Brand of Gemfibrozil, BBC/228, MolPort-001-794-413, NINDS_000138, Pharmascience Brand of Gemfibrozil, HMS1568L09, HMS1920B07, HMS2090K14, HMS2091H11, HMS2095L09, HMS2230H24, HMS3259M12, HMS3655C06, HMS3712L09, Pharmakon1600-10500313, 5-(2,5-dimethylphenoxy)-2,2-, BB_SC-04837, BCP08437, HY-B0258, KS-00000VK6, KS-000046JO, Warner Lambert Brand of Gemfibrozil, Warner-Lambert Brand of Gemfibrozil, ZINC1530641, ZX-AS004442, Tox21_110613, Tox21_201997, Tox21_302784, A0G461, BBL010807, BDBM50110590, BG0205, CCG-40111, CG0035, DL-414, GP1460, MFCD00079335, NSC757024, s1729, SBB012457, STK618740, AKOS001606691, Tox21_110613_1, AB03034, AC-4225, API0002816, CS-2244, DB01241, KS-5192, LS-1085, MCULE-4563546953, NC00565, NSC-757024, VA11004, IDI1_000138, SEL11160931, NCGC00016794-01, NCGC00016794-02, NCGC00016794-03, NCGC00016794-04, NCGC00016794-05, NCGC00016794-06, NCGC00016794-07, NCGC00016794-08, NCGC00016794-10, NCGC00016794-11, NCGC00016794-13, NCGC00016794-14, NCGC00022722-03, NCGC00022722-04, NCGC00022722-05, NCGC00022722-06, NCGC00022722-07, NCGC00256601-01, NCGC00259546-01, AN-12208, CC-28946, H900, SAM002564211, SC-17669, ST072198, Terry White Chemists Brand of Gemfibrozil, SBI-0051391.P003, AB0013344, AB2000253, AX8032912, TL8002081, 2,2-Dimethyl-5-(2,5-zlyloxy)valeric acid, AB00052003, FT-0626641, FT-0700924, G0368, Gemcor, Lopid, Jezil,Gen-Fibro, Gemfibrozil, C07020, D00334, J10068, Z-0832, AB00052003-15, AB00052003-16, AB00052003_17, AB00052003_18, A818037, C-15436, 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeric Acid, I01-1855, SR-01000000056-3, SR-01000000056-4, SR-01000000056-6, SR-01000000056-7, 2,2-Dimethyl-5-(2,5-dimethylphenoxy)-pentanoic acid, BRD-K11129031-001-05-1, Gemfibrozil, British Pharmacopoeia (BP) Reference Standard, Gemfibrozil, European Pharmacopoeia (EP) Reference Standard, 5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID, Gemfibrozil, United States Pharmacopeia (USP) Reference Standard, Gemfibrozil, Pharmaceutical Secondary Standard; Certified Reference Material, Gemfibrozil for system suitability, European Pharmacopoeia (EP) Reference Standard, 4TX

ID: 824

InChIKey: HEMSJKZDHNSSEW-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1C(=O)OC2=CC(=C(C(=C2)C)C(=O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 99613
synonyms found at PubChem are:
Lecanoric acid, 480-56-8, Orsellinate depside, NSC 249981, BRN 2172778, CHEBI:15871, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid, o-orsellinate depside, 2,4-Dihydroxy-6-methylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester, Lecanoricacid, beta-Resorcylic acid, 6-methyl-, 4-(6-methyl-beta-resorcylate), 4-(2,4-dihydroxy-6-methylbenzoyloxy)-2-hydroxy-6-methylbenzoic acid, Spectrum_000499, SpecPlus_000150, Spectrum2_000211, Spectrum3_000162, Spectrum4_001485, Spectrum5_000189, UNII-D0M65TKS0F, AC1Q60PF, D0M65TKS0F, BSPBio_001623, KBioGR_002089, KBioSS_000979, SPECTRUM200070, 4-10-00-01527 (Beilstein Handbook Reference), MLS000563107, DivK1c_006246, SPBio_000221, AC1L410R, SCHEMBL3797774, CHEMBL1451874, CTK8D5276, KBio1_001190, KBio2_000979, KBio2_003547, KBio2_006115, KBio3_001123, DTXSID60197384, MolPort-003-665-749, ZINC901518, CCG-38414, LMPK13080001, NSC249981, AKOS015916261, NSC-249981, SDCCGMLS-0066390.P001, NCGC00095468-01, NCGC00095468-02, NCGC00095468-03, 4CN-1488, AC-20266, SMR001215955, LS-143448, C02868, SR-01000841840, SR-01000841840-2, BRD-K77578964-001-02-8, I14-51682, .beta.-Resorcylic acid, 4-(6-methyl-.beta.-resorcylate), 4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoic acid, Benzoic acid, 2,4-dihydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester, Benzoic acid, 2,4-dihydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester (9CI), Benzoic acid,2,4-dihydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester, Benzoic acid,4-dihydroxy-6-methyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester

ID: 825

InChIKey: HEURTYMJWQPWNN-LBPRGKRZSA-N
SMILES: COC1=CC(=O)O[C@H](C1)CCC2=CC(=C(C=C2)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 22217085
synonyms found at PubChem are:
38146-60-0, 11-Methoxytetrahydroyangonin, Tetrahydro-11-methoxyiangonin, HEURTYMJWQPWNN-LBPRGKRZSA-N, ZINC3978525, 2H-Pyran-2-one, 6-[2-(3,4-dimethoxyphenyl)ethyl]-5,6-dihydro-4-methoxy-, (S)-, (S)-6-(3,4-dimethoxyphenethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one, 6-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one #

ID: 826

InChIKey: HEURTYMJWQPWNN-UHFFFAOYSA-N
SMILES: COC1=CC(=O)OC(C1)CCC2=CC(=C(C=C2)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 592220
synonyms found at PubChem are:
11,12-DIMETHOXYDIHYDROKAWAIN, KBio1_001340, SpecPlus_000300, AC1LC0JM, Spectrum2_001958, Spectrum3_001058, Spectrum4_001198, Spectrum5_001756, BSPBio_002616, KBioGR_001895, DivK1c_006396, SPBio_002055, KBio3_001836, TETRAHYDROTRIMETHYLHISPIDIN, CHEBI:110179, MolPort-006-668-586, CCG-39496, 7,8-Dihydro-11,12-dimethoxykawain, MCULE-8002733162, 5,6,7,8-Tetrahydro-11-methoxyyangonin, NCGC00178573-01, BRD-A86977540-001-02-6, 4-Methoxy-6-(3,4-dimethoxyphenethyl)-5,6-dihydro-2H-pyran-2-one, 2-[2-(3,4-dimethoxyphenyl)ethyl]-4-methoxy-2,3-dihydropyran-6-one, 6-[(3,4-Dimethoxyphenyl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one, 6-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one, NCGC00178573-02!2-[2-(3,4-dimethoxyphenyl)ethyl]-4-methoxy-2,3-dihydropyran-6-one

ID: 827

InChIKey: HEYVINCGKDONRU-UHFFFAOYSA-N
SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 62884
synonyms found at PubChem are:
Bupropion hydrochloride, 31677-93-7, Bupropion Hcl, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride, Wellbutrin, Zyban, Wellbutrin XL, Bupropion hydrocloride, Wellbutrin SR, Amfebutamone hydrochloride, Budeprion, Forfivo XL, Zyban (pharmaceutical), Voxra, Bupropion (hydrochloride), Amfebutamone (Bupropion) HCl, EINECS 250-759-9, BW 323, NSC 315851, 2-(tert-Butylamino)-3'-chloropropiophenone hydrochloride, m-Chloro-alpha-tert-butylaminopropiophenone hydrochloride, alpha-(tert-Butylamino)-m-chloropropiophenone hydrochloride, HSDB 6988, m-Chloro-alpha-tert-butylaminopropionphenone hydrochloride, Amfebutamone(Bupropion), (+-)-2-(tert-Butylamino)-3'-chloropropiophenone hydrochloride, (+-)-alpha-tert-Butylamino-3-chloropropiophenone hydrochloride, 2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone Hydrochloride, (+/-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride, 1-(3-CHLOROPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE HYDROCHLORIDE, DSSTox_CID_24561, DSSTox_RID_80314, DSSTox_GSID_44561, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one HCl, Propiophenone, 2-(tert-butylamino)-3'-chloro-, hydrochloride, (+-)-, Budeprion XL, 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, hydrochloride, (+-)-, SMR000058423, Budeprion XL 300, BW-323, NSC315851, Amfebutamon hydrochlorid, Amfebutamon hydrochloride, SR-01000002989, Quomem, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydrochloride, Wellbutrin XR, Wellbutrin Retard, Wellbutrin (TN), Prestwick_668, Bupropion hydrochloride [USAN:USP], EINECS 252-243-9, Zyban (TN), Bupropion hydrochloride [USAN:USP:JAN], PubChem20752, Amfebutamone (Bupropion), AC1L1XZA, NCGC00016807-01, CAS-31677-93-7, CHEMBL1698, SCHEMBL41602, MLS000069376, MLS001401370, MLS002320678, SPECTRUM1504174, CHEBI:3220, Jsp005899, DTXSID6044561, CTK8B3357, HY-B0403A, CPI-300, HEYVINCGKDONRU-UHFFFAOYSA-N, HMS1568B20, HMS1922F09, Pharmakon1600-01504174, Bupropion hydrochloride (JAN/USP), BCP22394, KS-00000XL2, Tox21_110621, Tox21_301844, Tox21_500166, AC-196, ANW-42367, BG0117, BW-323U66, CCG-39085, MFCD00055209, NSC758686, AKOS015844544, Tox21_110621_1, AB02273, API0001440, BCP9000462, CCG-100911, CS-2503, KS-1034, LP00166, NC00161, NSC-315851, NSC-758686, ACM34841366, NCGC00015122-11, NCGC00093650-01, NCGC00093650-02, NCGC00093650-03, NCGC00093650-04, NCGC00093650-05, NCGC00180895-01, NCGC00180895-02, NCGC00255927-01, NCGC00260851-01, Propiophenone, hydrochloride, (.+-.)-, 34841-36-6, AK-75760, AN-16061, BC208314, CPD000058423, SAM001246723, SC-12179, SMR001338824, BCP0726000049, 31677-93-7 (HCl), AB0012179, AB2000567, AX8118984, KB-224632, LS-125089, TC-010273, 4CH-007122, AM20060780, B3649, EU-0100166, FT-0081218, FT-0623288, S2452, ST24027672, V2047, 77B937, D00817, I06-19, J10311, M-5146, Bupropion hydrochloride, >=98% (HPLC), solid, A820950, I06-0019, SR-01000002989-2, Wellbutrin;Zyban;Voxra;Budeprion;Aplenzin;Bupropion, SR-01000002989-10, (+/-)-2-(t-butylamino)-3'-chloropropiophenone hydrochloride, 1-Propanone,1-dimethylethyl)amino]-, hydrochloride, (.+-.)-, Bupropion Hydrochloride 1.0 mg/ml in Methanol (as free base), (.+-.)-2-(tert-Butylamino)-3'-chloropropiophenone hydrochloride, Bupropion hydrochloride, United States Pharmacopeia (USP) Reference Standard, (+/-)-1-(3-Chlorophenyl)-2- [(1,1-dimethylethyl)amino]- 1-propanone hydrochloride, 1-(3-CHLOROPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-1-PROPANE, MONOHYDROCHLORIDE, Bupropion Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, ( inverted question mark)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride, Bupropion hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, AC1LCWCM, AKOS026750042, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one; hydron; chloride

ID: 828

InChIKey: HFHZKZSRXITVMK-UHFFFAOYSA-N
SMILES: CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4641
synonyms found at PubChem are:
oxyphenbutazone, Oxyphenylbutazone, Oxifenylbutazon, Oxiphenbutazone, Butapirone, Flamaril, Oxazolidin, Tandearil, Tanderil, Oxyphenobutazone, p-Oxyphenylbutazone, Oxi-Fenibutol, 129-20-4, Artroflog, Butaflogin, Butanova, Butazonic, Butilene, Crovaril, Deflogin, Etrozolidina, Flanaril, Floghene, Flogistin, Flogitolo, Flogodin, Flogoril, Flogostop, Flopirina, Idrobutazina, Infammil, Ipabutona, Isobutazina, Isobutil, Offitril, Oxibutol, Oxybuton, Oxyphentamin, Pirabutina, Piraflogin, Poliflogil, Rapostan, Tandacote, Tandalgesic, Tendearil, Visubutina, Flogal, Frabel, Infamil, Iridil, Mysite, Neofen, Optimal, Oxalid, Remazin, Reumox, Rumapax, Telidal, Valioil, Metabolite I, Neo-Farmadol, Oxazolidin-Geigy, p-Hydroxyphenylbutazone, Californit, Oxiphenbutazonum, Usaf Ge-14, Hydroxyphenylbutazon, Oxifenbutazona, Aradinum, Butanora, Flegmostam, Oxazolioin, Portoril, Reunabutal, Telidac, Genal, Oxyphenbutazonum, Cinophen-N, Tanderal, Ossifenbutazone [DCIT], BM 1, 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-butylpyrazolidine, 1-(p-Hydroxyphenyl)-2-phenyl-4-butyl-3,5-pyrazolidinedione, Oxifenbutazona [INN-Spanish], Oxyphenbutazonum [INN-Latin], Oxyphenbutazone [INN], Oxyphenbutazone anhydrous, 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione, 4-Butyl-1-(p-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione, 4-Butyl-2-(4-hydroxyphenyl)-1-phenyl-3,5-dioxopyrazolidine, 4-Butyl-2-(p-hydroxyphenyl)-1-phenyl-3,5-pyrazolidinedione, 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-, Oxyphenyl butazone, CCRIS 6717, 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine, 3,5-Dioxo-1-phenyl-2-(p-hydroxyphenyl)-4-N-butylpyrazolidene, G 27202, HSDB 3144, EINECS 204-936-2, 1-p-Hydroxyphenyl-2-phenyl-3,5-dioxo-4-N-butylpyrazolidine, NSC 526053, BRN 0307474, AI3-26792, MLS003373849, 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl, 3,5-Pyrazolidinedione, 4-butyl-1-(p-hydroxyphenyl)-2-phenyl-, CHEBI:76258, HFHZKZSRXITVMK-UHFFFAOYSA-N, Oxyphenbutazone (INN), 1-(p-Hydroxyphenyl)-2-phenyl-3,5-dioxo-4-N-butylpyrazolidine, AB00052064_08, DSSTox_CID_25291, DSSTox_RID_80784, DSSTox_GSID_45291, metabolite, Ossifenbutazone, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-pyrazolidine-3,5-dione, Hydroxyphenylbutazone, SR-05000001689, metabolitie, Romaxin, Suganril, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-1,2-diazolidine-3,5-dione, 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, NCGC00016389-01, CAS-129-20-4, OPB, Reozon (TN), Oxyphenbutazone (TN), Spectrum_001073, AC1L1IMG, Oxyphenbutazone, Tanderil, Prestwick0_001049, Prestwick1_001049, Prestwick2_001049, Prestwick3_001049, Spectrum2_000153, Spectrum3_000535, Spectrum4_001155, Spectrum5_000998, D06ZPS, Oxyphenbutazone (anhydrous), AC1Q6L3L, CHEMBL1228, SCHEMBL25857, BSPBio_000978, BSPBio_002149, KBioGR_001729, KBioSS_001553, labotest-bb lt00134684, DivK1c_000302, SPECTRUM1500455, SPBio_000286, SPBio_002909, BPBio1_001076, DTXSID1045291, CTK8G2232, HMS500P04, KBio1_000302, KBio2_001553, KBio2_004121, KBio2_006689, KBio3_001649, MolPort-003-666-251, NINDS_000302, BDBM200298, HMS1571A20, HMS1920D20, HMS2091L20, HMS2098A20, HMS2236G07, HMS3373B01, HMS3715A20, Pharmakon1600-01500455, BCP20014, Tox21_110414, CCG-38944, NSC526053, NSC757261, SBB057012, AKOS024362800, Tox21_110414_1, API0006917, DB03585, MCULE-3785704527, NSC-526053, NSC-757261, VZ36732, IDI1_000302, NCGC00094748-01, NCGC00094748-02, NCGC00094748-03, NCGC00094748-04, NCGC00094748-07, AN-23036, SBI-0051471.P003, LS-128612, 3, 4-butyl-1-(p-hydroxyphenyl)-2-phenyl-, AB00052064, FT-0673468, ST50993915, WLN: T5VNNV EHJ BR DQ & CR & E4, 3, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-, OXYPHENBUTAZONE 4-HYDROXYPHENYLBUTAZONE, C19494, D08324, C-44320, J-005659, SR-05000001689-1, SR-05000001689-3, BRD-A33749298-001-05-0, 1-(p-hydroxyphenyl)-2-phenyl-4-butylpyrazolidine-3,5-dione, 3,5-Pyrazolidinedione,4-butyl-1-(4-hydroxyphenyl)-2-phenyl-, 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl- (9CI), 3,5-Pyrazolidinedione, 4-butyl-1-(p-hydroxyphenyl)-2-phenyl- (VAN), 3,5-Pyrazolidinedione, 4-butyl-1-(p-hydroxyphenyl)-2-phenyl- (VAN) (8CI)

ID: 829

InChIKey: HFJFXXDHVWLIKX-UHFFFAOYSA-N
SMILES: CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 44134711
synonyms found at PubChem are:
84226-12-0, R(+)-ETICLOPRIDE, S(-)-ETICLOPRIDE, S(-)Eticlopride hydrochloride, SCHEMBL6535494, R (+)-Eticloride hydrochloride, CTK8G2716, R (+)-Eticlopride hydrochloride, HMS1570L06, Pharmakon1600-01506039, NSC759849, CCG-213969, NSC-759849, R(+)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide HCl, R(+)-3-Chloro-5-ethyl-N- [(1-ethyl-2-pyrrolidinyl)methyl]-6- hydroxy-2-methoxybenzamide HCl, S(-)-3-Chloro-5-ethyl-N- [(1-ethyl-2-pyrrolidinyl)methyl]-6- hydroxy-2-methoxybenzamide HCl

ID: 830

InChIKey: HGBLNBBNRORJKI-WCABBAIRSA-N
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3(CCCCC3)N)C(=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 19003
synonyms found at PubChem are:
CYCLACILLIN, ciclacillin, Ciclacillum, Vastcillin, Bastcillin, Cyclapen, Aminocyclohexylpenicillin, Citosarin, Syngacillin, Ultracillin, Calthor, Vipicil, Wyvital, Ciclacillinum, Ciclacilline, Orfilina, Cyclapen-W, Ciclacilina, 3485-14-1, Noblicil, Peamezin, (1-Aminocyclohexyl)penicillin, Ciclacilina [INN-Spanish], Ciclacilline [INN-French], Ciclacillinum [INN-Latin], Aminocyclohexyl penicillin, Wy-4508, 6-(1-Aminocyclohexanecarboxamido)penicillanic acid, WY 4508, AC 98, 6-(1-Aminocyclohexylcarboxamido)penicillanic acid, Cyclacillin [USAN], Penicillin, (aminocyclohexyl)-, AC-PC, Vastcillin (TN), Cyclapen-W (TN), Cyclacillin (USAN), UNII-72ZJ154X86, NSC88789, EINECS 222-470-8, NSC 88789, WY4508, BRN 0938663, CHEBI:31444, 72ZJ154X86, (2S,5R,6R)-6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, 6-(1-Aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, NCGC00016629-01, CAS-3485-14-1, C-12104, 6beta-(1-aminocyclohexanecarboxamido)-2,2-dimethylpenam-3alpha-carboxylic acid, (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(1-Aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, MLS002694856, Cyclacillin [USAN:USP], NSC-88789, Cyclapen (TN), Ciclacillin [INN], Prestwick0_001120, Prestwick1_001120, Prestwick2_001120, Prestwick3_001120, DSSTox_CID_2861, (Aminocyclohexyl)penicillin, D00HWO, Ciclacillin (JP15/INN), Ciclacillin (JP17/INN), DSSTox_RID_76762, DSSTox_GSID_22861, SCHEMBL33900, BSPBio_001260, SPBio_003120, AC1L2D99, BPBio1_001385, GTPL4817, CHEMBL1200356, DTXSID9022861, CTK1C2902, CYCLACILLIN (200 MG), HGBLNBBNRORJKI-WCABBAIRSA-N, HMS1571O22, ZINC3830609, Tox21_110534, 6-(1-Aminocyclohexanecarboxamido)-3, BDBM50350474, AKOS030530775, DB01000, NCGC00179238-01, LS-55797, NCI60_041965, AB00514059, C12766, D01334, BRD-K89046952-001-03-4, WLN: T45 ANV ESTJ F1 F1 GVQ CMV- AL6TJ AZ, 3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, (2S,5R,6R)-6-[(1-aminocyclohexane)amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(1-aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo-, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(1-aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo- (8CI), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(1-aminocyclohexanecarboxamido)-3,3-dimethyl-7-oxo-(8CI), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(1-aminocyclohexyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-

ID: 831

InChIKey: HGCGJTZCWZFGBT-XUIVZRPNSA-N
SMILES: CC1=C(S[C@](C1=O)(C)/C=C(\C)/C=C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 445629
synonyms found at PubChem are:
Thiolactomycin, Antibiotic 2-200, 82079-32-1, (R)-(+)-Thiolactomycin, (+)-Thiolactomycin, BRN 4423670, (R-(E))-3,5-Dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone, 2(5H)-Thiophenone, 3,5-dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-, (R-(E))-, TLM, 2(5H)-Thiophenone, 4-hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-, (S-(E))-, 4-HYDROXY-3,5-DIMETHYL-5-(2-METHYL-BUTA-1,3-DIENYL)-5H-THIOPHEN-2-ONE, (2R)-5-hydroxy-2,4-dimethyl-2-[(1E)-2-methylbuta-1,3-dienyl]thiophen-3-one, (5R)-Thiolactomycin, 1fj4, 2vb8, 4c6x, (R)-THIOLACTOMYCIN, D04JTY, D05GMV, D0H6VY, AC1L9IB6, Lopac0_000908, SCHEMBL12099108, SCHEMBL13332161, HMS3262F18, ZINC4099011, Tox21_500908, SM-101, AKOS027325299, CCG-204990, DB04302, LP00908, NCGC00094221-01, NCGC00094221-02, NCGC00261593-01, LS-153230, EU-0100908, C11165, T 9567, SR-01000076067, SR-01000076067-1, (4-R)(2E,5E)-2,4,6-Trimethyl-3-hydroxy-2,5,7-octatriene-4-thiolide, (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dienyl]thiophen-2-one, [R-(E)]-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone, (2R)-5-hydroxy-2,4-dimethyl-2-[(1E)-2-methylbuta-1,3-dien-1-yl]-2,3-dihydrothiophen-3-one

ID: 832

InChIKey: HGUVPEBGCAVWID-KETMJRJWSA-N
SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441381
synonyms found at PubChem are:
Saponarin, 20310-89-8, Isovitexin-7-O-glucoside, Saponaretin-7-O-glucoside, Isovitexin-7-O-beta-D-glucopyranoside, UNII-3081Z76OX9, isovitexin 7-O-glucoside, AC1L9B2G, 3081Z76OX9, SCHEMBL2489122, CHEBI:75439, 7-O-(beta-D-glucosyl)isovitexin, DTXSID10174201, HGUVPEBGCAVWID-KETMJRJWSA-N, MolPort-039-339-115, ZINC4097454, Apigenin 6-C-glucosyl-7-O-glucoside, CCG-208416, Apigenin-6-C-glucoside -7-O-glucoside, 4H-1-Benzopyran-4-one, 6-.beta.-D-glucopyranosyl-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-, FT-0645085, C08064, SR-05000002259, SR-05000002259-2, (1S)-1,5-anhydro-1-[7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol, 4H-1-Benzopyran-4-one, 3-((6-O-(6-deoxy-beta-L-mannofuranosyl)-beta-O-galactofuranosyl)oxy)-7-((6-deoxy-beta-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-, 5-hydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]-7-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one

ID: 833

InChIKey: HHVIBTZHLRERCL-UHFFFAOYSA-N
SMILES: CS(=O)(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6213
synonyms found at PubChem are:
Dimethyl sulfone, Methyl sulfone, 67-71-0, Methylsulfonylmethane, Sulfonylbismethane, DIMETHYLSULFONE, Dimethyl sulphone, Methane, sulfonylbis-, sulfonyldimethane, Sulphonylbismethane, methylsulfone, METHANESULFONYLMETHANE, DMSO2, Methylsulfonyl methane, UNII-9H4PO4Z4FT, NSC 63345, Methane, 1,1'-sulfonylbis-, METHYL SULFONYL METHANE, CCRIS 2938, (methylsulfonyl)methane, EINECS 200-665-9, 9H4PO4Z4FT, CHEMBL25028, AI3-25306, CHEBI:9349, HHVIBTZHLRERCL-UHFFFAOYSA-N, methyl sulfonmethane, dimethylsulfon, C2H6O2S, dimethylsulphone, methy sulfone, Lignisul MSM, Sulfonylbis-methane, Opti MSM, Sulfone, dimethyl-, (methylsulphonyl)methane, Dimethyl sulfone, 98%, 2-Thiapropane2,2-dioxide, ACMC-209o0h, MolMap_000019, AC1L1M1F, DSSTox_CID_23937, DSSTox_GSID_43937, KSC352Q8H, SPECTRUM1505358, DTXSID4043937, CTK2F2883, MolPort-003-666-648, KS-00000V5O, NSC63345, ZINC4658606, Tox21_303712, ANW-35391, BDBM50026473, NSC-63345, AKOS015897615, CCG-214558, MCULE-3320409932, NE10495, RL04588, RTR-022731, TRA0007185, CAS-67-71-0, NCGC00095990-01, NCGC00357027-01, AN-23767, CJ-12200, KB-50116, LS-90358, DB-050533, TL8004770, TR-022731, FT-0625160, M0509, M1239, EN300-79559, C11142, 74380-EP2269993A1, 74380-EP2270002A1, 74380-EP2308857A1, 74380-EP2371797A1, 74380-EP2371798A1, 74380-EP2371800A1, 74380-EP2371804A1, 90984-EP2280012A2, 90984-EP2305248A1, InChI=1/C2H6O2S/c1-5(2,3)4/h1-2H, 162163-EP2281815A1, A835859, I09-1058, F0001-1776, Z417007936, Dimethyl sulfone, Standard for quantitative NMR, TraceCERT(R), Methylsulfonylmethane, United States Pharmacopeia (USP) Reference Standard, Methylsulfonylmethane, Pharmaceutical Secondary Standard; Certified Reference Material, 54841-73-5

ID: 834

InChIKey: HHVVFSZNIUHMEJ-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(N1C(=O)C3=CC=CC=C3)C=CC(=C2)OC)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4177957
synonyms found at PubChem are:
1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid, 1601-19-0, NCGC00015138-01, AC1N4FBL, Lopac-B-1183, Lopac0_000110, SCHEMBL1082631, CHEMBL1256943, CTK0H5535, DTXSID40400323, HHVVFSZNIUHMEJ-UHFFFAOYSA-N, HMS3260E22, ZINC4475078, Tox21_500110, AKOS030619726, CCG-204205, LP00110, NCGC00015138-02, NCGC00015138-03, NCGC00015138-04, NCGC00093607-01, NCGC00093607-02, NCGC00260795-01, KB-217819, EU-0100110, FT-0720797, B 1183, SR-01000075704, SR-01000075704-1, (1-Benzoyl-2-methyl-5-methoxy-3-indolyl)acetic acid, 1-Benzoyl-2-methyl-5-methoxy-1H-indole-3-acetic acid, 1-benzoyl-5-methoxy-2-methyl-1H-Indole-3-acetic acid, 1H-Indole-3-aceticacid, 1-benzoyl-5-methoxy-2-methyl-, 2-(1-benzoyl-5-methoxy-2-methylindol-3-yl)acetic acid, (1-benzoyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid

ID: 835

InChIKey: HIGSLXSBYYMVKI-UHDJGPCESA-N
SMILES: CN\1C=CC=C/C1=C\[NH+]=O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5359226
synonyms found at PubChem are:
PRALIDOXIME CHLORIDE, 2-PAM chloride, Protopam chloride, pralidoxime, Pralidoxine chloride, ComboPen, 51-15-0, Pyridine-2-aldoxime methochloride, Pyridinium aldoxime methochloride, 2-Pyridine aldoxime methyl chloride, N-Methylpyridine-2-aldoxime chloride, 2-Pyridine-aldoxime chloride, N-Methylpyridinium chloride 2-aldoxime, N-Methylpyridinium-2-aldoxime chloride, Protopam, UNII-38X7XS076H, 2-Hydroxyiminomethyl-1-methylpyridinium chloride, 1-Methyl-2-pyridinium aldoxime chloride, 1-Methyl-2-aldoximinopyridinium chloride, 2-Formyl-1-methylpyridinium chloride oxime, 2-Formyl-N-methylpyridinium oxime chloride, 2-PAM, EINECS 200-080-9, N-Metylpyridinium-2-aldoxime chloride, NSC 164614, 2-Pyridinealdoxime methochloride, 1-Methyl-2-formylpyridinium chloride oxime, MLS000028727, CHEBI:8355, 38X7XS076H, 2-(Hydroxyiminomethyl)-1-methylpyridinium chloride, Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, chloride, SMR000059189, DSSTox_CID_3495, DSSTox_RID_77053, DSSTox_GSID_23495, Pyridinium, 2-formyl-1-methyl-, chloride, oxime, 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium chloride, NSC164614, CAS-51-15-0, NCGC00016226-01, Pralidoxime chloride [USAN], Pralidoximchlorid, 1-Methylpyridinium-2-aldoxime Chloride, Pralidoximechloride, Pralidoxime chloride [USAN:USP], Protopam (TN), Pralidoxime (INN), Pam 2Cl, 2-PAM (chloride), AC1NSDWQ, Opera_ID_228, AC1Q1RUT, Q-201609, C7H9N2O.HCl, D0X7NU, Pralidoxime chloride (USP), Pyridinium, chloride, oxime, SCHEMBL61419, 2-[(1E)-(hydroxyimino)methyl]-1-methylpyridin-1-ium chloride, MLS001076535, MLS002222315, MLS003876809, SCHEMBL1650343, DTXSID1023495, MolPort-004-440-359, HMS1570N08, HMS2097N08, HMS2232F12, HMS3259I04, HMS3714N08, WLN: T6KJ A1 B1UNQ &G, Tox21_110316, s4575, AKOS001094374, AKOS015892104, AKOS016339594, Tox21_110316_1, CCG-220943, KS-5324, NSC-164614, NCGC00178286-05, AN-41590, U602, LS-132536, M0819, ST50825032, EN300-50184, D00469, J10435, M-2760, SR-01000721910, I02-2928, SR-01000721910-3, (hydroxyimino)(1-methyl(2-pyridyl))methane, chloride, [(E)-(1-methyl-2-pyridylidene)methyl]-oxo-ammonium chloride, [(E)-(1-methylpyridin-2-ylidene)methyl]-oxoazanium chloride, Pyridinium, 2-[(hydroxyimino)methyl]-1-methyl-, chloride (1:1), Pralidoxime chloride, United States Pharmacopeia (USP) Reference Standard

ID: 836

InChIKey: HIHZDNKKIUQQSC-UHFFFAOYSA-N
SMILES: CC1=C(N(C(=O)N(C1=O)C)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5640
synonyms found at PubChem are:
5-Methylurapidil, 5-Methyl-urapidil, Urapidil, 5-Methyl-, 5 Methylurapidil, 34661-85-3, UNII-1HLS600135, CHEMBL420060, C21H31N5O3, 1HLS600135, 6-((3-(4-(2-Methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3,5-trimethyl-2,4(1H,3H)-pyrimidinedione, 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3,5-trimethylpyrimidine-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, 6-((3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3,5-trimethyl-, 5-Methyl-6[[3-[4-(2-methoxyphenyl)-1-piperazinyl]-propyl]-amino]-1,3-dimethyluracil, Lopac-U-101, AC1L1KSW, D0V6DJ, AC1Q6CC3, URAPIDIL 5-METHYL-, Lopac0_001275, GTPL489, URAPIDIL 5-METHYL-, MLS000860044, SCHEMBL6375436, CTK4H2779, HMS2232C19, HMS3263P12, HMS3373B21, ZINC2012436, Tox21_501275, BDBM50033112, MFCD00078602, PDSP1_001618, PDSP2_001602, CCG-205348, LP01275, ACM34661853, NCGC00016067-01, NCGC00016067-02, NCGC00016067-03, NCGC00016067-04, NCGC00016067-05, NCGC00094511-01, NCGC00094511-02, NCGC00094511-03, NCGC00261960-01, 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3,5-trimethylpyrimidine-2,4(1h,3h)-dione, SMR000326902, LS-174487, EU-0101275, U-101, L000080, SR-01000075287, J-001436, J-019692, SR-01000075287-1, 5-Methyl-6[[3-[4-(o-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil, 2,4(1H,3H)-Pyrimidinedione,6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3,5-trimethyl-, 6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione

ID: 837

InChIKey: HIMXGTXNXJYFGB-UHFFFAOYSA-N
SMILES: C1(=O)C(=O)NC(=O)NC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5781
synonyms found at PubChem are:
Alloxan, 50-71-5, 2,4,5,6(1H,3H)-Pyrimidinetetrone, Mesoxalylurea, Mesoxalylcarbamide, ALLOXANE, Pyrimidine-2,4,5,6(1H,3H)-tetraone, Alloxan 7169, Urea, mesoxalyl-, Barbituric acid, 5-oxo-, 2,4,5,6-Tetraoxohexahydropyrimidine, Pyrimidinetetrone, 1,3-diazinane-2,4,5,6-tetrone, NSC 7169, UNII-6SW5YHA5NG, 2,4,5,6-Pyrimidintetron, 5,6-dioxouracil, pyrimidine-2,4,5,6(1H,3H)-tetrone, 5-Oxobarbituric acid, 2,4,5,6-Pyrimidintetron [Czech], EINECS 200-062-0, 6SW5YHA5NG, 2,4,5,6-Pyrimidintetrone, AI3-15282, CHEBI:76451, HIMXGTXNXJYFGB-UHFFFAOYSA-N, hexahydropyrimidine-2,4,5,6-tetrone, AE-562/40299936, mesoxalyl-Urea, C4H2N2O4, CCRIS 9509, HSDB 7493, 2xgm, 5-oxo-barbiturate, Alloxan tetrahydrat, 5-oxo-barbituric acid, Spectrum_001080, SpecPlus_000865, WLN: T6MVMVVVJ, 2,5,6-Pyrimidintetron, AC1Q6DDS, Spectrum2_000531, Spectrum3_000615, Spectrum4_000606, Spectrum5_001490, AC1L1L4H, 2,4,5,6-pyrimidinetetrone, SCHEMBL64547, BSPBio_002150, KBioGR_001132, KBioSS_001560, DivK1c_006961, SPECTRUM1500802, SPBio_000541, C4H2N2O4.H2O, SCHEMBL9652639, CHEMBL1096009, DTXSID5044946, CTK1H1240, CTK2E6589, CTK2E7798, CTK2E7799, CTK2E7800, KBio1_001905, KBio2_001560, KBio2_004128, KBio2_006696, KBio3_001650, NSC7169, MolPort-001-780-132, 2,5,6-Tetraoxohexahydropyrimidine, 2,5,6(1H,3H)-Pyrimidinetetrone, 6-hydroxy-2,4,5-triketopyrimidine, BB_NC-02211, NSC-7169, ZINC1631379, 1338AB, 7131AF, BBL002915, CCG-39561, STK378289, AKOS005448465, 2,4,5,6(1H,3H) Pyrimidinetetrone, 2,5-Pyrimidinedione, 4,6-dihydroxy-, 4,5-Pyrimidinedione, 2,6-dihydroxy-, ACM3237501, MCULE-9690188027, NE10422, TRA0026839, NCGC00095912-01, NCGC00095912-02, AJ-28456, AN-24381, CC-07067, L937, LS-16374, 1,3-dihydropyrimidine-2,4,5,6-tetraone, 2,4,5(3H)-Pyrimidinetrione, 6-hydroxy-, 4,5,6(1H)-Pyrimidinetrione, 2-hydroxy-, AX8002193, DB-019799, KB-259557, A0216, FT-0621991, ST50561909, T7904, EN300-21254, AB00052179-03, 5,5-dihydroxy-hexahydro-pyrimidine-2,4,6-trione, A828261, C-02076, I14-19031, F8881-2259, InChI=1/C4H2N2O4/c7-1-2(8)5-4(10)6-3(1)9/h(H2,5,6,8,9,10, 61066-33-9, 61066-34-0, 61066-35-1, 61127-23-9, LXN

ID: 838

InChIKey: HIPIENNKVJCMAP-UHFFFAOYSA-N
SMILES: CC(=CC1C(C1(C)C)CO)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 110685
synonyms found at PubChem are:
Chrysanthemyl alcohol, Chrysanthemol, cis-Chrysanthemol, CHEBI:81217, 2,2-Dimethyl-3-(2-methylpropenyl)cyclopropanemethanol, 5617-92-5, [2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropyl]methanol, EINECS 227-045-0, Spectrum_001321, SpecPlus_000337, AI3-20836, Spectrum2_001768, Spectrum3_001332, Spectrum4_001654, Spectrum5_000527, AC1Q7C5Q, BSPBio_003083, KBioGR_002147, KBioSS_001801, SPECTRUM300566, [2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropyl]methanol #, DivK1c_006433, SCHEMBL522961, SPBio_001635, CHEMBL1318346, KBio1_001377, KBio2_001801, KBio2_004369, KBio2_006937, KBio3_002303, HIPIENNKVJCMAP-UHFFFAOYSA-N, 18383-59-0, AC1L3845, CCG-38818, AKOS015910737, FCH1115112, SDCCGMLS-0066572.P001, ACM18383590, NCGC00095607-01, NCGC00095607-02, ST50824477, C17611, Chrysanthemyl alcohol, mixture of cis and trans, SR-05000002388, SR-05000002388-1, Chrysanthemyl alcohol, mixture of cis and trans, 98%, I14-40837, [2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropyl]methan-1-ol, Cyclopropanemethanol, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, Cyclopropanemethanol, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (cis,trans-(+/-))-, Cyclopropanemethanol,2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-,(1R,3S)-rel-

ID: 839

InChIKey: HIYAVKIYRIFSCZ-CVXKHCKVSA-N
SMILES: C[C@H]1CCC2([C@@H](C[C@H]([C@H](O2)C(C)C(=O)C3=CC=CN3)C)C)O[C@H]1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 40486
synonyms found at PubChem are:
Calcimycin, Ionophore A23187, A23187, Antibiotic A23187, A 23187, CHEBI:3305, C29H37N3O6, 52665-69-7, A-23187, EINECS 258-084-1, Calcium ionophore A23187, 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-, Spectrum_001976, AC1Q5THY, UPCMLD-DP093, AC1L23UC, CBiol_001742, BSPBio_001576, KBioGR_000296, KBioSS_000296, KBioSS_002542, DivK1c_000618, SCHEMBL258988, CHEMBL1434752, DTXSID1040405, UPCMLD-DP093:001, UPCMLD-DP093:002, UPCMLD-DP093:003, HMS501O20, KBio1_000618, KBio2_000296, KBio2_002533, KBio2_002864, KBio2_005101, KBio2_005432, KBio2_007669, KBio3_000591, KBio3_000592, NINDS_000618, Bio1_000028, Bio1_000517, Bio1_001006, Bio2_000296, Bio2_000776, HMS1361O18, HMS1791O18, HMS1989O18, HMS3402O18, CCG-208023, CCG-208154, IDI1_000618, IDI1_034046, SMP2_000029, NCGC00161647-01, LS-42155, C11309, BRD-A19134330-001-03-8, 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl), (6S-(6-alpha(2S*,3S*),8-beta(R*),9-beta,11-alpha))-, 5-(methylamino)-2-({(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid, 5-(methylamino)-2-[[(2S,3R,5R,8S,9S)-3,5,9-trimethyl-2-[1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid, 5-(methylamino)-2-[[(3S,4S,7R,9R,10S)-3,7,9-trimethyl-10-[1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-5,11-dioxaspiro[5.5]undecan-4-yl]methyl]-1,3-benzoxazole-4-carboxylic acid, 5-(methylamino)-2-[[(3S,4S,7R,9R,10S)-3,7,9-trimethyl-10-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-5,11-dioxaspiro[5.5]undecan-4-yl]methyl]-1,3-benzoxazole-4-carboxylic acid, 6S-[6.alpha.(2S*,3S*),8.beta.(R*),9.beta.11. alpha.]-5-(Methylamino)-2-[[3,9,11-trimethyl-8- [1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7- dioxaspiro[5,5]undec-2-yl]methyl-4- benzoxazolecarboxylic aci

ID: 840

InChIKey: HJBWJAPEBGSQPR-GQCTYLIASA-N
SMILES: COC1=C(C=C(C=C1)/C=C/C(=O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 717531
synonyms found at PubChem are:
3,4-DIMETHOXYCINNAMIC ACID, 2316-26-9, 14737-89-4, Dimethylcaffeic acid, Caffeic acid dimethyl ether, (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid, Dimethyl caffeic acid, (E)-3-(3,4-dimethoxyphenyl)acrylic acid, (2E)-3-(3,4-dimethoxyphenyl)acrylic acid, (E)-3,4-dimethoxycinnamic acid, UNII-BVZ841PVJL, 3,4-Dimethoxy cinnamic acid, 3-(3,4-Dimethoxyphenyl)propenoic acid, 3-(3,4-dimethoxyphenyl)acrylic acid, (E)-3',4'-Dimethoxycinnamic acid, BVZ841PVJL, 3,4-Dimethoxyphenyl-2-propenoic acid, 3, 4-Dimethoxycinnamic acid, 3',4'-dimethoxycinnamic acid, CHEMBL320295, CHEBI:86549, NSC4323, trans-3,4-Dimethoxycinnamic acid, (e)-3-(3,4-dimethoxyphenyl)-2-propenoic acid, (E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid, 3,4-Dimethoxycinnamic acid, predominantly trans, HJBWJAPEBGSQPR-GQCTYLIASA-N, 3-(3,4-Dimethoxyphenyl)-2-propenoic Acid, (E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid, Cinnamic acid,4-dimethoxy-, (2E)-3-(3,4-Dimethoxyphenyl)-2-propenoic acid, W-107420, 2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, (2E)-, o-Methylferulic acid, 2-Propenoic acid,4-dimethoxyphenyl)-, SMR000112198, 3-(3,4-dimethoxy-phenyl)-acrylic acid, 3,4-Dimethoxycinnamic acid, (E)-, EINECS 238-801-4, PubChem8267, 3,4-Dimethoxy[7,8,9,-13C3]-cinnamic Acid, AC1LET0J, AC1Q5RAL, Spectrum5_000142, bmse010210, O,O'-Dimethylcaffeic Acid, AC1Q46HL, 3,4-dimethoxy-cinnamic acid, cinnamic acid,3,4-dimethoxy, SCHEMBL81317, BSPBio_001672, SPECTRUM210567, MLS000570053, MLS002695959, BIDD:ER0423, SPECTRUM1505130, ARONIS023564, E)-3,4-Dimethoxycinnamic acid, 3,4-Dimethoxybenzeneacrylic acid, BBB/229, MolPort-000-489-707, MolPort-004-288-306, (E)-3,4-dimethoxy cinnamic acid, 3,4-dimethoxy-trans-cinnamic acid, 3,4-Dimethoxycinnamic acid, 8CI, HMS2268F17, ZINC116202, ACT13062, ALBB-004705, BB_NC-00397, NSC-4323, NSC43569, ZX-AL002152, ZX-AN004651, ZX-AS003468, ZX-AT018225, BBL009859, BDBM50341141, CCG-38678, NSC-43569, OR6575, SBB005722, STK298625, AKOS000119628, AC-8314, AN-8131, BBV-201132, CS-W020726, MCULE-4648711215, RP17505, RTR-010813, SDCCGMLS-0066525.P001, VZ33918, NCGC00095522-01, NCGC00095522-02, NCGC00095522-03, 4CN-2862, AJ-11508, AK-89652, AK323813, KB-26027, KB-28359, SC-02686, SC-70733, ST097456, AB0008393, AB0071555, AB1000947, TL8001930, TR-010813, D1728, ST24041414, TL80090024, M-2122, 3-(3,4-Dimethoxyphenyl)-(E)-2-Propenoic acid, trans-3-(3,4-Dimethoxyphenyl)prop-2-enoic acid, 3-(3,4-Dimethoxyphenyl)-2-propenoic acid, 9CI, 7R-0613, A113300, AE-641/01606018, SR-01000712420, 2-Propenoic acid,3-(3,4-dimethoxyphenyl)-,(2E)-, 2-Propenoic acid,3-(3,4-dimethoxyphenyl)-,(E)-, I01-1879, J-010506, SR-01000712420-2, 2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, (E)-, 2-Propenoic acid,3-(3,4-dimethoxyphenyl)-, (2E)-, 3,4-Dimethoxycinnamic acid, predominantly trans, 99%, BRD-K96256403-001-05-0, I14-10526, 49C7DB89-C3D8-411B-B043-A8335FDDD98E, F3095-1806, InChI=1/C11H12O4/c1-14-9-5-3-8(4-6-11(12)13)7-10(9)15-2/h3-7H,1-2H3,(H,12,13)/b6-4

ID: 841

InChIKey: HJESSLHNQMBHEX-LSIGHCQTSA-N
SMILES: CC(=O)O[C@H]1C[C@H](C(C2[C@]1(C3CC[C@]4([C@@H](OC(=O)C5C4([C@@]3([C@@H](C2)O)C)O5)C(=O)OC)C)C)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708587
synonyms found at PubChem are:
KBio2_006325, Spectrum_000709, SpecPlus_000172, Spectrum2_000381, Spectrum3_000704, Spectrum4_001409, Spectrum5_000178, BSPBio_002487, KBioGR_001798, KBioSS_001189, SPECTRUM100650, DivK1c_006268, SPBio_000561, SCHEMBL10019458, KBio1_001212, KBio2_001189, KBio2_003757, KBio3_001707, CCG-38653, SDCCGMLS-0066406.P001, NCGC00178634-01, DESACETYL (7)KHIVORINIC ACID, METHYL ESTER, BRD-A24436948-001-02-6

ID: 842

InChIKey: HJESSLHNQMBHEX-XZMBGRNKSA-N
SMILES: CC(=O)O[C@H]1C[C@H](C(C2[C@]1(C3CC[C@]4([C@@H](OC(=O)C5C4([C@@]3([C@H](C2)O)C)O5)C(=O)OC)C)C)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708583
synonyms found at PubChem are:
SR-05000002741, Spectrum_000705, SpecPlus_000168, Spectrum2_000441, Spectrum3_000130, Spectrum4_001407, Spectrum5_000174, BSPBio_001780, KBioGR_001794, KBioSS_001185, SPECTRUM100638, DivK1c_006264, SPBio_000482, SCHEMBL10019451, KBio1_001208, KBio2_001185, KBio2_003753, KBio2_006321, KBio3_000940, CCG-38690, SDCCGMLS-0066371.P001, NCGC00179010-01, SR-05000002741-1, SR-05000002741-2, 7beta-HYDROXY-7-DESACETOXYKHIVORINIC ACID, METHYL ESTER

ID: 843

InChIKey: HJHVRVJTYPKTHX-HTMVYDOJSA-N
SMILES: CCCN1CCC[C@H]2[C@H]1CC3=C(C2)NN=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 55397
synonyms found at PubChem are:
(-)-Quinpirole hydrochloride, QUINPIROLE HYDROCHLORIDE, Quinpirole HCl, 85798-08-9, UNII-T6I2W5V2K1, Quinpirole hydrochloride [USAN], LY 171555, T6I2W5V2K1, LY-171,555, Q-102, DSSTox_CID_25519, DSSTox_RID_80926, DSSTox_GSID_45519, (-)-(4aR,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo(3,4-g)quinoline monohydrochloride, Quinpirole hydrochloride (USAN), 1H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, monohydrochloride, (4aR-trans)-, SMR000326933, CAS-85798-08-9, NCGC00016954-05, 85760-74-3, SR-01000075397, AC1L1IZP, D00YAS, LY-171555, (-)quinpi-role hydrochloride, (?)-Quinpirole hydrochloride, C13H21N3.HCl, MLS000860075, MLS002222194, SCHEMBL121129, CHEMBL1256574, DTXSID8045519, CTK8F1419, HY-B1752A, AOB5029, ( C)-Quinpirole monohydrochloride, MolPort-003-666-734, MolPort-003-959-422, HMS1571K08, Tox21_110707, Tox21_500990, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrzolo(3,4-g)quinoline, AKOS024456359, AKOS030530543, Tox21_110707_1, API0008813, CCG-222294, LP00990, NCGC00016954-10, NCGC00261675-01, LY171555, LS-129351, CS-0013777, EU-0100990, D05682, SR-01000597925, SR-01000075397-1, SR-01000597925-1, (-)-Quinpirole hydrochloride, >=98% (HPLC), solid, (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline hydrochloride, (4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline hydrochloride, 1H-Pyrazolo(3,4-g)quinolone, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, monohydrochloride,(4aR-trans)-, trans-( C)-(4aR)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline monohydrochloride

ID: 844

InChIKey: HJLSLZFTEKNLFI-UHFFFAOYSA-N
SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5479
synonyms found at PubChem are:
tinidazole, 19387-91-8, Tindamax, Fasigyn, Tinidazol, 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitro-1H-imidazole, Simplotan, Tricolam, Trimonase, Bioshik, Fasigin, Tinidazolum, Sorquetan, Pletil, CP 12574, Tinidazol [INN-Spanish], Tinidazolum [INN-Latin], 1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole, UNII-033KF7V46H, C8H13N3O4S, CCRIS 7621, 1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole, HSDB 7362, EINECS 243-014-4, 1H-Imidazole, 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-, BRN 0618182, CP-12574, 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole, Ethyl (2-(2-methyl-5-nitro-1-imidazolyl)ethyl)sulfone, CP-12,574, MLS000069717, 1H-Imidazole, 1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-, CHEBI:63627, HJLSLZFTEKNLFI-UHFFFAOYSA-N, 033KF7V46H, 1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole, NCGC00016741-01, 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole, SMR000058194, CAS-19387-91-8, DSSTox_CID_3676, DSSTox_RID_77141, DSSTox_GSID_23676, 1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole, 1-(ethylsulfonyl)-2-(2-methyl-5-nitroimidazolyl)ethane, 1-[2'-(Ethylsulfonyl)-Ethyl]-2-Methyl-5-Nitroimidazole, Imidazole, 1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-, Fasygin, Glongyn, Amtiba, SR-01000000210, timidazole, 1-(2'-(ethylsulfonyl)-Ethyl]-2-Methyl-5-Nitroimidazole, Fasigyntrade mark, Tindamaxtrade mark, Tinidazole,(S), Simplotantrade mark, Tinidazole [USAN:BAN:INN:JAN], Haisigyn (TN), Tindamax (TN), Prestwick_136, Tinidazole [USAN:USP:INN:BAN:JAN], Spectrum_001266, Opera_ID_779, SpecPlus_000708, AC1L1KFT, Prestwick0_000766, Prestwick1_000766, Prestwick2_000766, Prestwick3_000766, Spectrum2_000648, Spectrum3_001512, Spectrum4_000230, Spectrum5_001715, D0O4SE, CHEMBL1220, Oprea1_342844, SCHEMBL21141, BSPBio_000812, BSPBio_003183, KBioGR_000899, KBioSS_001746, methyl-5-nitro-1H-imidazole, 5-23-05-00067 (Beilstein Handbook Reference), MLS001146883, MLS001424192, DivK1c_006804, SPECTRUM1502127, SPBio_000655, SPBio_002751, BPBio1_000894, Tinidazole (JP17/USP/INN), DTXSID4023676, CTK4E1372, KBio1_001748, KBio2_001746, KBio2_004314, KBio2_006882, KBio3_002683, MolPort-000-810-622, MolPort-006-819-596, 1-(2-(ethylsulfonyl)ethyl)-2-, HMS1570I14, HMS1921L06, HMS2052C09, HMS2090B14, HMS2092D14, HMS2097I14, HMS2231E23, HMS3374P07, HMS3394C09, HMS3652A08, HMS3714I14, Pharmakon1600-01502127, ZINC113446, BCP20694, HY-B0177, KS-00000J1U, Tox21 110586, Tox21_110586, BBL010767, CCG-39907, NSC758189, s4068, STK801761, Tinidazole (oral), Mission Pharmacal, AKOS000747070, Tox21_110586_1, AC-1618, AN-6513, CS-2055, DB00911, KS-5180, MCULE-2580495783, NC00346, NSC-758189, NCGC00016741-02, NCGC00016741-03, NCGC00016741-04, NCGC00016741-05, NCGC00016741-06, NCGC00016741-07, NCGC00016741-09, NCGC00022212-03, NCGC00022212-04, NCGC00022212-05, AJ-11437, BAS 00604596, BC203912, CPD000058194, LS-78715, SAM001246913, ST024770, SBI-0052674.P002, AB0012837, AB1009400, KB-212509, ST2403077, 4CH-017486, AB00053176, FT-0675241, VU0239922-6, D01426, K-5725, Tinidazole, VETRANAL(TM), analytical standard, AB00053176-16, AB00053176_17, AB00053176_18, A813669, SR-01000000210-3, SR-01000000210-5, SR-01000000210-6, BRD-K89125793-001-05-4, I14-45143, Z56763819, 1-(2-Ethanesulfonyl-ethyl)-2-methyl-5-nitro-1H-imidazole, 1-[2-(2-Ethylsulfonyl)ethyl]-2-methyl-5-nitro-imidazole, Tinidazole, European Pharmacopoeia (EP) Reference Standard, 1H-Imidazole,1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-, Tinidazole, United States Pharmacopeia (USP) Reference Standard, TIMTEC-BB SBB006917 TINIDAZOLE 1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-1h-imidazol

ID: 845

InChIKey: HJMQDJPMQIHLPB-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C2=NNC(=O)C=C2)OC(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5723
synonyms found at PubChem are:
zardaverine, 101975-10-4, Zardaverina, Zardaverinum, Zardaverine [INN], Zardaverinum [INN-Latin], UNII-TQ358GWH6Y, Zardaverina [INN-Spanish], 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE, C12H10F2N2O3, 6-(4-(Difluoromethoxy)-3-methoxyphenyl)-3(2H)-pyridazinone, TQ358GWH6Y, CHEMBL313842, CHEBI:46548, HJMQDJPMQIHLPB-UHFFFAOYSA-N, 6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone, NCGC00016106-04, 6-[4-(difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one, 3(2H)-Pyridazinone,6-[4-(difluoromethoxy)-3-methoxyphenyl]-, CAS-101975-10-4, 3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]- [CAS], DSSTox_CID_22559, DSSTox_RID_80048, DSSTox_GSID_42559, 6-(4-(difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one, 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone, SMR000449313, SR-01000076204, Zaradaverine, 1mkd, 1xor, Tocris-1046, ACMC-20ccb1, AC1L1KZT, AC1Q6BYY, Prestwick0_000977, Prestwick1_000977, Prestwick2_000977, Prestwick3_000977, Lopac-Z-3003, D0F0CS, UPCMLD-DP159, Lopac0_001260, SCHEMBL13334, BSPBio_001013, BSPBio_001346, KBioGR_000066, KBioSS_000066, MLS000758207, MLS001401422, SPBio_002924, BPBio1_001115, DTXSID8042559, SCHEMBL14810549, UPCMLD-DP159:001, UPCMLD-DP159:002, BDBM14769, CTK4A0496, KBio2_000066, KBio2_002634, KBio2_005202, KBio3_000131, KBio3_000132, 3-pyridazinol, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-, 6-(4-difluoromethoxy-3-methoxyphenyl)-3(2H)pyridazinone, MolPort-003-960-230, MolPort-044-724-428, Bio2_000066, Bio2_000546, HMS1361D08, HMS1571C15, HMS1791D08, HMS1989D08, HMS2051O09, HMS2090L06, HMS2098C15, HMS2235H08, HMS3267C08, HMS3370L18, HMS3393O09, HMS3402D08, HMS3715C15, BCP06509, ZINC9230249, Tox21_110307, 4165AH, BS0210, MFCD00867059, AKOS024456348, Tox21_110307_1, Zardaverine phosphodiesterase inhibitor, CCG-100782, CCG-205334, CS-1011, DB02918, NC00032, Zardaverine, phosphodiesterase inhibitor, IDI1_033816, NCGC00016106-01, NCGC00016106-02, NCGC00016106-03, NCGC00016106-05, NCGC00016106-06, NCGC00016106-07, NCGC00016106-08, NCGC00016106-09, NCGC00016106-10, NCGC00016106-11, NCGC00016106-13, NCGC00024963-01, NCGC00024963-02, NCGC00024963-03, NCGC00024963-04, NCGC00024963-05, CC-35668, CPD000449313, HY-15485, SAM001247053, SBI-0051227.P002, LS-171799, AB00513983, EU-0101260, FT-0631019, W-5158, Z 3003, AB00513983-03, C-16835, J-000529, SR-01000076204-1, SR-01000076204-3, SR-01000076204-5, BRD-K37561857-001-04-9, BRD-K37561857-001-06-4, BRD-K37561857-001-13-0, 6-(4-difluoromethoxy-3-methoxy-phenyl)-3[2h]-pyridazinone, 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one, 6-(3,4-Dimethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-2H-pyridazin-3-one

ID: 846

InChIKey: HJORMJIFDVBMOB-GFCCVEGCSA-N
SMILES: COC1=C(C=C(C=C1)[C@@H]2CC(=O)NC2)OC3CCCC3

biological descriptors:

CFTR relevance: Phosphodiesterase 4 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"PC Chao" "KL Hamilton"

CID is 158758
synonyms found at PubChem are:
(S)-(+)-rolipram, 85416-73-5, S-(+)-Rolipram, (S)-ROLIPRAM, (+)-rolipram, S- (+)-Rolipram, UNII-H6G4VMQ24K, H6G4VMQ24K, CHEMBL325795, CHEBI:59540, (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE, (S)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one, (4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-pyrrolidin-2-one, S-rolipram, 1oyn, Rolipram, (+)-, 1xn0, AC1L4KJV, D02FZD, (R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one, MLS006011228, SCHEMBL5321568, CTK8G3018, DTXSID30234634, HJORMJIFDVBMOB-GFCCVEGCSA-N, MolPort-003-983-800, HMS3267P21, HY-B0392, KS-000017MS, ZINC2000919, 2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, (4S)-, BDBM50042056, BS0165, s2127, AKOS024456541, CS-2478, DB03606, NCGC00381709-04, CJ-30872, SMR004702988, BCP0726000229, R0183, X5034, AB01274743-01, AB01274743_02, BRD-K65856711-001-01-0, (4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one, UNII-K676NL63N7 component HJORMJIFDVBMOB-GFCCVEGCSA-N, (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one

ID: 847

InChIKey: HJORMJIFDVBMOB-LBPRGKRZSA-N
SMILES: COC1=C(C=C(C=C1)[C@H]2CC(=O)NC2)OC3CCCC3

biological descriptors:

CFTR relevance: Phosphodiesterase 4 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"PC Chao" "KL Hamilton"

CID is 448055
synonyms found at PubChem are:
(R)-(-)-Rolipram, 85416-75-7, (R)-ROLIPRAM, (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one, (-)-ROLIPRAM, (4R)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE, R-Rolipram, UNII-DPX51KUP08, DPX51KUP08, CHEMBL430893, CHEBI:40133, 1xmy, NCGC00016899-01, CAS-61413-54-5, Rolipram, (R)-, Rolipram, (-)-, PubChem18284, Tocris-0905, Tocris-1349, Tocris-1350, 1q9m, 1ro6, 3g4k, AC1L9LJS, Lopac-R-6520, D01RUN, (R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one, SCHEMBL576805, ZINC4982, KS-00000QDB, MolPort-003-983-801, HMS3267P19, BCP14111, ANW-64684, BDBM50042058, HY-16900A, AKOS015891287, CCG-208064, CS-3246, DB04149, NCGC00015898-01, NCGC00015898-02, NCGC00015898-10, NCGC00016899-02, NCGC00016899-03, NCGC00016899-04, NCGC00016899-05, NCGC00024862-01, NCGC00024862-02, NCGC00024862-03, AC-22384, AJ-08238, AS-31755, P623, ZB000602, KB-210162, TC-153429, R0182, 416R757, SR-01000597573, I01-8873, SR-01000597573-1, BRD-K75516118-001-01-7, (4R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one, UNII-K676NL63N7 component HJORMJIFDVBMOB-LBPRGKRZSA-N, (R)-(-)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, 2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, (R)-, 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-, 4RR, 4SR

ID: 848

InChIKey: HJYWSATZDBEAOS-OGFXRTJISA-N
SMILES: CC(=NCCCC[C@H](C(=O)O)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957581
synonyms found at PubChem are:
L-N6-(1-Iminoethyl)lysine hydrochloride, EU-0100663, CHEMBL1600325, Tox21_500663, CCG-221967, LP00663, NCGC00094025-01, NCGC00261348-01, I 8021, SR-01000076244, SR-01000076244-1

ID: 849

InChIKey: HKEAFJYKMMKDOR-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Mazur" "S Barnes" "J Prasain" "SM Rowe" "JP Clancy" "LC Pyle" "JC Fulton" "PA Sloane" "K Backer"

CID is 5385074
synonyms found at PubChem are:
NSC380711, 3681-99-0, Pneranin, 1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]hexitol, AC1NTOCB, MLS006011792, CHEMBL1319403, SCHEMBL13906069, MolPort-005-943-411, AC-702, BBL030170, STL146384, AKOS005720902, MCULE-8247528856, NSC-380711, PXT0004736, NCGC00096060-01, SMR004703482, ST081391, I06-0429, Hexitol, 1,5-anhydro-1-C-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-, 7-hydroxy-3-(4-hydroxyphenyl)-8-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-8-[3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6 -tetrahydropyran-2-yl)]chromen-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-8-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-8-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one

ID: 850

InChIKey: HKHDOQCAWUXKTG-UHFFFAOYSA-L
SMILES: C1=CC=[N+](C=C1)C[N+]2=CC=CC=C2.[I-].[I-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 2729272
synonyms found at PubChem are:
32405-50-8, AC1MBPIR, dipyridiniomethan-diiodid, DTXSID00369583, MolPort-002-915-746, HMS1530D13, CCG-55689, AKOS001046026, MCULE-7143658107, 1,1-METHYLENEDIPYRIDINIUM DIIODIDE, 1,1'-Methylenedi(pyridin-1-ium) diiodide, FT-0606158, 1-(pyridin-1-ium-1-ylmethyl)pyridin-1-ium diiodide, SR-01000644703-1

ID: 851

InChIKey: HKHOVJYOELRGMV-XYOKQWHBSA-N
SMILES: C1=CC=C(C=C1)NC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5328771
synonyms found at PubChem are:
Tyrphostin B48, Tyrphostin AG 494, AG 494, 133550-35-3, AG-494, Tyrphostin AG-494, (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylacrylamide, alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide, CHEMBL56731, 139087-53-9, (E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE, N-Phenyl-3,4-dihydroxybenzylidenecyanoacetamide, SR-01000075495, Tocris-0619, AC1NS5AZ, Lopac-T-4318, 2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide, Lopac0_001147, MLS002172496, BDBM4304, cid_5328771, ZINC15335, MolPort-003-983-737, MolPort-044-724-385, HMS2232N04, HMS3263F15, BCP29134, Tox21_501147, BS0027, HSCI1_000168, AKOS024458583, CCG-205221, LP01147, NCGC00016019-01, NCGC00016019-02, NCGC00016019-03, NCGC00016019-04, NCGC00016019-05, NCGC00016019-06, NCGC00024687-01, NCGC00024687-02, NCGC00024687-03, NCGC00261832-01, SMR001254117, KB-250696, LS-186978, LS-187620, RT-011208, B6378, EU-0101147, T 4318, J-006403, SR-01000075495-1, SR-01000075495-3, BRD-K34533029-001-01-0, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide, (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide, 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-, (2E)-, 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-,(2E)-

ID: 852

InChIKey: HKODIGSRFALUTA-JTLQZVBZSA-N
SMILES: C/C=C\1/C[C@H]([C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5280906
synonyms found at PubChem are:
SENECIONINE, Aureine, Senecionin, 130-01-8, 12-Hydroxysenecionan-11,16-dione, UNII-BO6N1U5YG6, CCRIS 4340, HSDB 3535, NSC 89935, BRN 0934445, BO6N1U5YG6, Integerrimine, Intergerrimine, Squalidine, AI3-51771, CHEBI:9107, C18H25NO5, NSC89935, Senecionan-11,16-dione, 12-hydroxy-, Senecionine, analytical standard, SCHEMBL896098, Senecionan-11, 12-hydroxy-, CHEMBL362153, MolPort-003-927-243, Senecionine, >=95.0% (GC), HY-N2560, NSC-89935, ZINC95851257, CCG-208634, NCGC00163621-01, (Z)-ethylidene-hydroxy-dimethyl-[?]dione, LS-144941, CS-0022892, C06176, J-005736, WLN: T55-12-1A Q EN IOVY OVO BUTJ KU2 M NQ N, WLN: T55-12- 1A Q EN IOVY OVO BUTJ KU2 M1 NQ N1, (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-, (5R,6R,9a1R,14aR,Z)-3-ethylidene-6-hydroxy-5,6-dimethyl-3,4,5,6,9,9a1,11,13,14,14a-decahydro-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 11002-70-3, 11024-76-3

ID: 853

InChIKey: HLBPOYVRLSXWJJ-PDSMFRHLSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@@H](CC4=C(C5=C(C=C24)OCO5)O)COC3=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 92122
synonyms found at PubChem are:
beta-Peltatin, beta-Peltatin A, PELTATIN B, Peltatin methyl ether, PELTATIN, BETA, 518-29-6, alpha-Peltalin A, NSC 24819, UNII-3U9W61G72Y, (-)-beta-peltatin, BRN 0099483, AI3-50532, NSC24819, CHEBI:74867, 3U9W61G72Y, NSC35471, .alpha.-Peltalin A, .beta.-Peltatin, .beta.-Peltatin A, MLS002702982, beta-peltatin-a, Peltatin, beta-, Furo[3',7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-10-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.beta.,8a.alpha.)]-, .beta.-Peltatin-B, (-)-|A-Peltatin, Spectrum_001780, AC1L3NGM, Spectrum3_001096, Spectrum4_001925, Spectrum5_001882, BSPBio_002772, KBioGR_002270, KBioSS_002261, 5-19-10-00670 (Beilstein Handbook Reference), CHEMBL97543, SCHEMBL516627, SPECTRUM1504739, KBio2_002260, KBio2_004828, KBio2_007396, KBio3_001992, DTXSID10199732, MolPort-003-665-515, ZINC3871713, NSC-24819, NSC-35471, SDCCGMLS-0066768.P001, NCGC00161926-01, NCGC00161926-02, NCI60_001982, LS-101359, BRD-K13265046-001-02-1, (5aR,8aR,9R)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-, (5aR,8aR,9R)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, (5aR,8aR,9R)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one, (5R,5aR,8aR)-10-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-10-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha))-, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-10-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha))- (9CI), Naphtho[2,3-dioxole-6-carboxylic acid, 5,6,7,8-tetrahydro-9-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-, .gamma.-lactone

ID: 854

InChIKey: HLUCICHZHWJHLL-UHFFFAOYSA-N
SMILES: C1C2=CC(=O)C(=CC2=C3C1(COC4=C3C=CC(=C4O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 10138
synonyms found at PubChem are:
HEMATEIN, 475-25-2, Haematein, Hematine, Hydroxybrasilein, NSC7333, NSC 7333, EINECS 207-492-8, BRN 0093039, AI3-63013, CHEBI:90116, CTK8B3911, Benz[b]indeno[1,2-d]pyran-9(6H)-one, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-, 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one, 3,4,6a,10-Tetrahydroxy-6a,7-dihydrobenz(b)indeno(1,2-d)pyran-9(6H)-one, 6a,7-Dihydro-3,4,6a,10-tetrahydroxybenz(b)indeno(1,2-d)pyran-9(6H)-one, hematein,haematein,hydroxybrazilein,hydroxybrasilein,c.i.75290, hydroxybrazilein, 3,4,10,6a-tetrahydroxy-7,6a-dihydroindeno[2,1-c]chroman-9-one, 3,4,6a,10-tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one, Benz(b)indeno(1,2-d)pyran-9(6H)-one, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-, Haematine, Spectrum_001226, SpecPlus_000484, HEMATEIN (DYE), AC1L1UKK, Spectrum2_000612, Spectrum3_001540, Spectrum4_001698, Spectrum5_000376, AC1Q69YX, US8987474, Hematin, BSPBio_002960, KBioGR_001996, KBioSS_001706, 4-18-00-03343 (Beilstein Handbook Reference), DivK1c_006580, SCHEMBL169328, SPECTRUM1502253, SPBio_000544, CHEMBL1360563, CHEMBL1730100, KBio1_001524, KBio2_001706, KBio2_004274, KBio2_006842, KBio3_002460, HLUCICHZHWJHLL-UHFFFAOYSA-N, MolPort-002-521-684, BDBM152157, Hematein, for microscopy (Hist.), NSC-7333, ACM475252, ANW-43441, BBL027922, CCG-39273, MFCD00036187, SBB006464, STL372875, AKOS024282604, MCULE-5679142519, SDCCGMLS-0066710.P001, SMP1_000180, NCGC00017347-02, NCGC00017347-03, NCGC00095664-01, NCGC00095664-02, AN-23484, LS-33432, ST057211, TR-017520, FT-0632182, FT-0732507, A827263, C-18746, SR-05000002557, SR-05000002557-1, I14-59644, Benz[b]indeno[1, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-, 3,4,6a,10-tetrahydroxy-6a,7-dihydrobenzo[b]indeno[1,2-d]pyran-9(6H)-one, 6a,7-Dihydro-4,6a,9,10-tetrahydroxybenz[b]indeno[1,2-d]pyran-3(6H)-one, 53986-81-5

ID: 855

InChIKey: HLWMLYNEZWIYMO-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1)N=C(C=C2C)NC3=C(C=CC(=C3)Cl)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "O Zegarra-Moran" "LJ Galietta" "GL Lukacs" "K Du" "AS Verkman" "N Pedemonte"

CID is 740915
synonyms found at PubChem are:
N-(5-chloro-2-methoxyphenyl)-4,6-dimethylquinolin-2-amine, (5-Chloro-2-methoxy-phenyl)-(4,6-dimethyl-quinolin-2-yl)-amine, AC1LERUI, BAS 01238481, Oprea1_491077, Oprea1_810748, SCHEMBL838087, MolPort-001-521-465, ZINC178556, STK078550, AKOS000602076, MCULE-3171750851, EU-0043833, SR-01000482932, SR-01000482932-1

ID: 856

InChIKey: HLXQFVXURMXRPU-UHFFFAOYSA-L
SMILES: C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 10921
synonyms found at PubChem are:
DECAMETHONIUM BROMIDE, Decamethonium dibromide, 541-22-0, Decacuran, Syncurine, Decamethonium (Bromide), Decamethylene bis(trimethylammonium bromide), Dekamethoniumbromid [Czech], Decametonio bromuro [DCIT], UNII-55C6RK944K, Decamethylenebis(trimethylammonium bromide), C 10 (VAN), Decamethonii bromidum [INN-Latin], EINECS 208-772-2, NSC 23004, Bromuro de decametonio [INN-Spanish], Bromure de decamethonium [INN-French], HL 8562, Decamethylene bis(trimethylammonium) dibromide, 55C6RK944K, Decamethylene-1,10-bistrimethylammonium dibromide, 1,10-Decanediaminium, N,N,N,N',N',N'-hexamethyl-, monobromide, Decane-1,10-bis(trimethylammonium bromide), DSSTox_CID_2886, Ammonium, decamethylenebis(trimethyl-, dibromide, DSSTox_RID_76774, DSSTox_GSID_22886, 1,10-Decanediaminium, N,N,N,N',N',N'-hexamethyl-, dibromide, CHEMBL1134, 1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2), Dekamethoniumbromid, 156-74-1 (Parent), Decametonio bromuro, decamethylenebis[trimethylammonium bromide], Decamethonii bromidum, C16H38N2, Bromuro de decametonio, Bromure de decamethonium, SR-01000003073, NCGC00163237-01, CAS-541-22-0, Decamethonium bromide [INN], Decamethonium bromide [USP:INN], AC1L1W8H, SCHEMBL487473, AC1Q1R43, C16H38N2.2Br, aa>> (1)iIeE<< degrees ., DTXSID2022886, MolPort-003-929-681, HMS1571A17, HMS2094A17, HMS2098A17, HMS3261M11, HMS3652G08, HMS3715A17, HY-B0570, Tox21_112035, Tox21_500385, 6379AF, MFCD00011779, s4072, AKOS024386263, Tox21_112035_1, CCG-213593, CS-2678, LP00385, MCULE-6709660253, NCGC00015323-11, NCGC00093814-01, NCGC00261070-01, LS-17290, aa>> E(R)Ithorn(1/4)(3/4) degrees ., EU-0100385, FT-0624484, ST51037214, D 1260, SR-01000003073-2, SR-01000003073-5, trimethyl-[10-(trimethylazaniumyl)decyl]azanium dibromide, trimethyl[10-(trimethylazaniumyl)decyl]azanium dibromide, N,N,N,N',N',N'-hexamethyldecane-1,10-diaminium dibromide, trimethyl[10-(trimethylamino)decyl]amine, bromide, bromide, 60869-65-0

ID: 857

InChIKey: HMAUJNAGOIPKDG-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(C(=C(C=C2O1)O)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5036604
synonyms found at PubChem are:
EUGENITOL, 5,7-dihydroxy-2,6-dimethylchromen-4-one, 491-48-5, 5,7-dihydroxy-2,6-dimethylchromone, 5,7-dihydroxy-2,6-dimethyl-4H-chromen-4-one, KBio2_001059, Spectrum_000579, SpecPlus_000031, Spectrum2_000749, Spectrum3_000183, Spectrum4_001500, Spectrum5_000239, AC1NN48K, BSPBio_001705, KBioGR_002139, KBioSS_001059, DivK1c_006127, SPBio_000738, CHEMBL3039487, CHEBI:92806, KBio1_001071, KBio2_003627, KBio2_006195, KBio3_001205, DTXSID70407683, CCG-38991, SDCCGMLS-0066844.P001, NCGC00179070-01, BRD-K46068882-001-02-7

ID: 858

InChIKey: HMJIYCCIJYRONP-UHFFFAOYSA-N
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3784
synonyms found at PubChem are:
isradipine, 75695-93-1, DynaCirc, Isradipin, Lomir, Isrodipine, Prescal, Esradin, Dynacirc CR, Clivoten, Dynacrine, Isradipinum [Latin], Isradipino [Spanish], Isradipino, Isradipinum, Rebriden, DynaCire, PN-200-110, DynaCire CR, (+-)-Isradipine, (+/-)-Isradipine, PN 200-110, PN 200, Isradipine (Dynacirc), Icaz, Isradipine, (+-)-Isomer, DynaCirc (TN), Isradipine [USAN:INN:BAN], Isradipine (USP/INN), 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, PN 205-033, PN 205-034, PN-205-033, PN-205-034, HMJIYCCIJYRONP-UHFFFAOYSA-N, C19H21N3O5, Isopropyl methyl (+-)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, PN-200110, DSSTox_CID_3179, DSSTox_RID_76907, DSSTox_GSID_23179, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-, methyl 1-methylethyl ester, (+-)-, 3-isopropyl 5-methyl 4-(benzo[c][1,2,5]oxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester, O5-methyl O3-propan-2-yl 4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, (+)-isradipine, 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv., 131970-21-3, 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester (9CI), 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, (+-)-, 4-(2,1,3-Benzooxadiazol-4-yl)-2.6-dimethyl-1,4-dihydro-3-isopropyloxycarbonylpyridine-5-carboxylic Acid Methyl Ester, 4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methhylethyl ester, 4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester, 4-(4-Benzofurazanyl)-1,4-dihydro-2,-6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester, 88977-22-4, isopropyl 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-3-pyridinecarboxylate, methyl 1-methylethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, SMR000466320, SMR002529690, SR-01000597526, Isradipine, (R)-Isomer, Isradipine, (S)-Isomer, Isradipine [USAN:USP:INN:BAN], NCGC00016931-01, (-)-Isradipine, (plusmn)-isradipine, Prescal (TN), CAS-75695-93-1, Isradipine(Dynacirc), Spectrum_000218, PN205033, PN205034, PN-200, PharmaNova, PN 205033, PN 205034, AC1L1GPE, Prestwick0_001021, Prestwick1_001021, Prestwick2_001021, Prestwick3_001021, (.+/-.)-Isradipine, PN 205 033, PN 205 034, D0HC8Q, D0Z7KE, CHEMBL1648, SCHEMBL34555, BSPBio_001201, KBioSS_000698, MLS000759425, MLS001424076, MLS002154106, MLS003915633, MLS006010138, SPBio_003062, AC1Q426L, BPBio1_001323, CHEBI:6073, CHEMBL315436, GTPL4488, CHEMBL3211306, DTXSID4023179, CTK8G0407, KBio2_000698, KBio2_003266, KBio2_005834, AOB5974, MolPort-003-848-292, HMS1571M03, HMS2051J12, HMS2098M03, HMS2235O12, HMS3268D21, HMS3393J12, HMS3655C17, HMS3715M03, Pharmakon1600-02300234, (non-Isotopelabelled)Isradipine-d7, ACT02697, BCP06719, HY-B0233, Tox21_110690, BDBM50436176, BG0371, CI0041, MFCD00153820, NSC759892, PN-200, s1662, AKOS015895129, Isradipine, >=98% (HPLC), solid, Tox21_110690_1, AC-8539, AN-7921, Antiviral (genital herpes), PharmaNova, API0003052, CCG-101027, CCG-213711, CS-2201, DB00270, HS-0085, NC00277, NSC-759892, RL04885, VA11116, KS-0000118G, NCGC00025341-01, NCGC00025341-02, NCGC00025341-03, NCGC00025341-06, ACM131970213, CPD002529690, K297, SAM001246584, SC-16999, AB2000202, LS-131190, LS-177211, AB00514007, FT-0627542, I0876, D00349, AB00514007_02, AB00514007_03, 695I931, I06-0364, J-513454, SR-01000597526-1, SR-01000597526-2, BRD-A90799790-001-03-3, BRD-A90799790-001-10-8, DynaCirc;Prescal;PN-200-110;Clivoten;Esradin;Dynacirc, Isradipine, European Pharmacopoeia (EP) Reference Standard, Isradipine, United States Pharmacopeia (USP) Reference Standard, DynaCirc, Prescal, PN-200-110, Clivoten, Esradin, Isradipine, Isopropyl Methyl 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimet, Isopropyl Methyl 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-,methyl 1-methylethyl ester, (+-)-, 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester, 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, (.+/-.)-, 3-Isopropyl 5-methyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate #, 3-methyl 5-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid methyl 1-methylethyl ester, 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Isopropyl Methyl Ester, Isopropyl methyl (.+/-.)-4-(4-benzfurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, Isopropyl methyl (.+/-.)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, O5-isopropyl O3-methyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

ID: 859

InChIKey: HMMYROQEJAZVGJ-CTOOOFERSA-N
SMILES: CCC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C)NC(=O)[C@@H]4CC5[C@@H](CC6=CNC7=CC=CC5=C67)N(C4)C)O.CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C)NC(=O)[C@@H]4CC5[C@@H](CC6=CNC7=CC=CC5=C67)N(C4)C)O.CC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C)NC(=O)[C@@H]4CC5[C@@H](CC6=CNC7=CC=CC5=C67)N(C4)C)O.C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5CC6[C@@H](CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 92044435
synonyms found at PubChem are:
Dihydroergotoxine (mesylate), HY-B0799, CS-3930

ID: 860

InChIKey: HMUJXQRRKBLVOO-AWEZNQCLSA-N
SMILES: COC1=CC=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 160481
synonyms found at PubChem are:
Isosakuranetin, 480-43-3, 4'-Methylnaringenin, Isosakutanetin, UNII-U02X7TF8UA, naringenin 4'-methyl ether, U02X7TF8UA, CHEMBL470266, CHEBI:27552, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone, Citrifoliol, (S)-5,7-dihydroxy-2-(4-methoxyphenyl)chroman-4-one, (2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-, (2S)-, 4'-Methoxy-5,7-dihydroxyflavonone, EINECS 207-551-8, AC1Q6KIP, D01FJE, AC1L4NP1, naringenin 4''-methyl ether, SCHEMBL676015, MEGxp0_001686, ACon1_000171, HMUJXQRRKBLVOO-AWEZNQCLSA-N, MolPort-001-742-462, 4'-methoxy-5,7-dihydroxyflavanone, HY-N2131, ZINC2146973, 5,7-dihydroxy-4''-methoxyflavanone, BDBM50325673, LMPK12140355, AKOS032948348, CCG-208396, MCULE-6964743359, NCGC00163576-01, NCGC00163576-02, 4CN-1144, CJ-33041, CS-0018682, FT-0632190, C05334, SR-05000002273, SR-05000002273-2, BRD-K19341706-001-01-7, (S)-5,7-Dihydroxy-2-(4-methoxy-phenyl)-chroman-4-one, (2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one, (S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-, (S)-

ID: 861

InChIKey: HNFPPWVGLWDXQQ-FJPSVTAHSA-N
SMILES: CC(=O)O[C@@H]1CC[C@@]2(C3CC[C@]4([C@@H](OC(=O)C=C4[C@@]3([C@@H](CC2C1(C)C)OC(=O)C)C)C5=COC=C5)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708514
synonyms found at PubChem are:
Spectrum_000694, SpecPlus_000015, AC1O8FBD, Spectrum2_000259, Spectrum3_000052, Spectrum4_001334, Spectrum5_000207, BSPBio_001803, KBioGR_001827, KBioSS_001174, SPECTRUM100205, DivK1c_006111, SPBio_000078, SCHEMBL13424818, KBio1_001055, KBio2_001174, KBio2_003742, KBio2_006310, KBio3_000983, CCG-39819, 3alpha-ACETOXYDIHYDRODEOXYGEDUNIN, NCGC00178996-01, BRD-A14098586-001-02-3, BRD-A14098586-001-03-1, [(1R,4bR,5R,8R,10aS,12aR)-5-acetyloxy-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-8-yl] acetate

ID: 862

InChIKey: HNIKIWUOAYSIGC-UHFFFAOYSA-N
SMILES: C1(=CC=CC=C1)COCC1ON=C(C(=O)OCC)C=1

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 90326175
synonyms found at PubChem are:
SCHEMBL15932085, HNIKIWUOAYSIGC-UHFFFAOYSA-N, Ethyl 5-benzyloxymethylisoxazole-3-carboxylate

ID: 863

InChIKey: HNNIWKQLJSNAEQ-UHFFFAOYSA-N
SMILES: CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 65464
synonyms found at PubChem are:
Benzydamine hydrochloride, 132-69-4, Benzydamine HCl, Benzindamine hydrochloride, Benzidamine hydrochloride, Benalgin, Benzidan, Benzyrin, Difflam, Dorinamin, Enzamin, Epirotin, Flogaton, Imotryl, Indolin, Oxinazin, Ririlim, Riripen, Salyzoron, Tantum, Tamas, Verax, Benzydamine (hydrochloride), UNII-K2GI407R4Q, EINECS 205-076-0, AF 864, Benzydamine hydrochloride [USAN:JAN], K2GI407R4Q, AF-864, 1-Benzyl-3-gamma-dimethylaminopropoxy-1H-indazole hydrochloride, 1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole hydrochloride, 1-benzyl-3-(3-[dimethylamino]propoxy)-1h-indazole hydrochloride, 1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole monohydrochloride, 1-Propanamine, N,N-dimethyl-3-((1-(phenylmethyl)-1H-indazol-3-yl)oxy)-, hydrochloride, 1-Propanamine, N,N-dimethyl-3-((1-(phenylmethyl)-1H-indazol-3-yl)oxy)-, monohydrochloride, C19H24ClN3O, DSSTox_CID_25293, DSSTox_RID_80786, DSSTox_GSID_45293, 1-Benzyl-3[3-dimethylamino)-propoxy]-1H-indazole, 1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole Hydrochloride, 1H-Indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-, monohydrochloride, 3-((1-Benzyl-1H-indazol-3-yl)oxy)-N,N-dimethylpropylamine monohydrochloride, SMR000544402, {3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine hydrochloride, NCGC00016397-01, CAS-132-69-4, dimethyl{3-[1-benzyl(1H-indazol-3-yloxy)]propyl}amine, chloride, SR-01000799149, 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride, Benzydamine, HCl, tantum hydrochloride, Prestwick_403, Tantum (TN), af864, AC1L23AM, SCHEMBL42644, labotest-bb lt00771795, MLS001216204, MLS001306431, MLS001333107, MLS001333108, MLS002222210, 642-72-8 (Parent), CHEMBL1528134, DTXSID1045293, CHEBI:31266, CTK8B3388, HNNIWKQLJSNAEQ-UHFFFAOYSA-N, MolPort-003-895-808, HMS1568L16, Pharmakon1600-01505975, BCP12133, EBD27358, KS-00000FQ4, Tox21_110420, ANW-42447, HY-30235A, NSC759276, s4165, SBB058129, Benzydamine hydrochloride (JAN/USAN), AKOS015994635, Tox21_110420_1, AC-6791, AN-9692, API0001625, CCG-213582, CS-4463, HS-1002, NSC-759276, 132-69-4 (HCl), NCGC00016397-04, AK-57903, LS-81422, SC-19739, 1-Benzyl-3-Hydroxy-1H-IndazoleSodiumSalt, AB0016836, AX8115986, KB-217937, B3751, FT-0662621, ST24030105, ST50411695, Benzydamine hydrochloride, analytical standard, D01410, J-006209, SR-01000799149-4, 1-benzyl-3-gamma-dimethylaminopropoxy-1h-indazolehydrochloride, 1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazolmonohydrochloride, 1-benzyl-3-[3-(dimethylamino)-propoxy]-1h-indazole hydrochloride, 3-(1-benzyl-1H-indazol-3-yloxy)-N,N-dimethylpropan-1-amine hydrochloride, 3-(1-benzylindazol-3-yl)oxy-N,N-dimethyl-propan-1-amine hydrochloride, 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine hydrochloride, 1-UEth>>u-3-[3-( paragraph signthorn(1/4)x>>u degrees +/->>u)+/-uNo>>u]-1H-ssAsso, MolPort-000-815-828, MCULE-5327094537, AKOS015899302, I14-11967

ID: 864

InChIKey: HOKIDJSKDBPKTQ-GLXFQSAKSA-N
SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CCC[C@H](C(=O)O)N)SC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 65536
synonyms found at PubChem are:
cephalosporin C, 7-(5-Amino-5-carboxyvaleramido)cephalosporanic acid, 61-24-5, UNII-3XIY7HJT5L, CHEBI:15776, EINECS 200-501-6, 3XIY7HJT5L, BRN 0065348, CEPHALOSPORIN-C, (6R,7R)-3-[(acetyloxy)methyl]-7-{[(5R)-5-amino-5-carboxypentanoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-8-oxo-, (6R-(6alpha,7beta(R*)))-, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(5-amino-5-carboxyvaleramido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), Cephalosporin C [BAN], 39879-21-5, Cephalosporin C [INN:BAN], Cephalosporin C disodium salt, C16H21N3O8S, EINECS 254-669-0, D0O4TL, Epitope ID:116208, AC1L23FV, SCHEMBL76583, 4-27-00-05902 (Beilstein Handbook Reference), CHEMBL482858, HOKIDJSKDBPKTQ-GLXFQSAKSA-N, 41279-77-0 (zinc salt), ZINC3977881, 57847-70-8 (potassium salt), EINECS 234-341-3, 59143-60-1 (mono-zinc salt), AKOS027381816, DB03313, 39879-21-5 (di-hydrochloride salt), 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-, (6R,7R)-, 51762-04-0 (mono-hydrochloride salt), Disodium (6R-(6alpha,7beta(R*)))-3-(acetoxymethyl)-7-((5-amino-5-carboxylato-1-oxopentyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, LS-149950, C00916, (6R,7R)-3-(acetyloxymethyl)-7-[[(5R)-5-amino-6-hydroxy-6-oxohexanoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 11111-12-9, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-8-oxo-, disodium salt, (6R-(6alpha,7beta(R*)))-

ID: 865

InChIKey: HOMGKSMUEGBAAB-UHFFFAOYSA-N
SMILES: C1CN(P(=O)(OC1)NCCCl)CCCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3690
synonyms found at PubChem are:
ifosfamide, Isophosphamide, 3778-73-2, Iphosphamide, Isofosfamide, Ifosfamid, Mitoxana, Naxamide, Iphosphamid, Isoendoxan, Ifex, I-Phosphamide, Holoxan, Cyfos, Ifsofamide, Holoxan 1000, ASTA Z 4942, Ifosfamida, Ifosfamidum, Ifosphamide, MJF 9325, (D,L)-Ifosfamide, isosfamide, (+-)-Ifosfamid, (+-)-Ifosphamide, (R,S)-Ifosphamide, NCI-C01638, Iso-Endoxan, MJF-9325, Ifosfamide Sterile, Ifosfamidum [INN-Latin], Ifosfamida [INN-Spanish], 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide, NSC 109724, NSC-109724, A 4942, Z 4942, Z-4942, Iphosphamid(e), Z4942, CCRIS 352, N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide, HSDB 7023, Ifosfamide [USAN:INN:BAN:JAN], N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide, 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, EINECS 223-237-3, NSC109724, IFEX (TN), NPFAPI-04, BRN 0611835, dexifosfamide, C7H15Cl2N2O2P, Ifosfamide (JAN/USP/INN), N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, CHEBI:5864, HOMGKSMUEGBAAB-UHFFFAOYSA-N, 2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd, N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide, N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide, (+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, (R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide, 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide, N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German], N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide, NCGC00016639-01, CAS-3778-73-2, DSSTox_CID_760, N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid, 2H-1,3,2-Oxazaphosphorin-2-amine, tetrahydro-N,3-bis(2-chloroethyl)-, 2-oxide, (+-)-, 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, DSSTox_RID_75775, DSSTox_GSID_20760, Q-101874, Iso Endoxan, N,3-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide, N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide, 1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide, 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide, N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine, 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI), 84711-20-6, SR-05000002022, ifomide, ifosfomide, Mitoxana;Ifex, N,3-bis(2-chloroethyl)-2-oxo-1,3,2?^{5}-oxazaphosphinan-2-amine, Ifosfamid A, (R)-Ifosfamide, (S)-Ifosfamide, 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorineoxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide, Mitoxana (TN), Isophosphamide,(S), Ifosfamide [USAN:USP:INN:BAN:JAN], NSC-109,724, Ifosfamide, >=98%, AC1L1GHW, Prestwick0_000833, Prestwick1_000833, Prestwick2_000833, Prestwick3_000833, D02TLO, Mitoxana, Ifex, Ifosfamide, SCHEMBL4885, CHEMBL1024, BSPBio_000785, KSC948G4P, MLS002154021, 3,} 2-oxazaphosphorine oxide, Ifex (TN) (Bristol Meyers), SPBio_002706, BPBio1_000865, GTPL7201, DTXSID7020760, CTK8E8347, KS-00000YBW, MolPort-003-666-704, BDBM189358, HMS1570H07, HMS2090M12, HMS2093N07, HMS2097H07, HMS2232O10, HMS3374B08, HMS3654B15, HMS3714H07, Pharmakon1600-01505480, {3-(2-Chloroethyl)-2-[(2-, BCP06596, WLN: T6NPOTJ AM2G BO B2G, Tox21_110539, Tox21_201815, Tox21_302775, BBL028071, CI0037, NSC759154, s1302, STL058690, AKOS005711213, Tox21_110539_1, AB02316, AC-2113, AN-6958, API0002976, CCG-213464, CS-1424, DB01181, MCULE-1480299331, NSC-759154, Ifosfamide, analytical reference material, NCGC00179435-01, NCGC00179435-02, NCGC00179435-03, NCGC00179435-06, NCGC00179435-07, NCGC00256413-01, NCGC00259364-01, AS-10978, CC-29468, HY-17419, LS-99799, NCI60_000233, SC-12120, SMR001233348, TA-01010, ACM1189701130, SBI-0206804.P001, AB0008491, AB2000039, KB-333868, AB00513932, FT-0603650, C07047, D00343, J10093, M-1494, 33899-EP2275420A1, 33899-EP2295055A2, 33899-EP2295416A2, 33899-EP2298748A2, 33899-EP2298764A1, 33899-EP2298765A1, 33899-EP2305642A2, 33899-EP2311453A1, AB00513932-06, AB00513932-07, AB00513932-08, AB00513932_09, AB00513932_10, 778I732, C-16296, I06-0494, SR-05000002022-1, SR-05000002022-3, SR-05000002022-5, BRD-A67097164-001-11-2, Ifosfamide, British Pharmacopoeia (BP) Reference Standard, Ifosfamide, European Pharmacopoeia (EP) Reference Standard, UNII-UM20QQM95Y component HOMGKSMUEGBAAB-AWEZNQCLSA-N, Ifosfamide, United States Pharmacopeia (USP) Reference Standard, 2,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxy-, 2,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd, 2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxy-, 2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd, N,3-bis(2-chloroethyl)-2-oxo-1,3,2$l;{5}-oxazaphosphinan-2-amine, (2S)-3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2|E5-oxazaphosphinan-2-one, {3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,} 2-oxazaphosphorine oxide, 1,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide, 2H-1,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide, 2H-1,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide, 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-one, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2$l;{5}-oxazaphosphinan-2-one, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2lambda5-oxazaphosphinan-2-one, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,2-oxazaphosphorine oxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,2-oxazaphosphorineoxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,2-oxazaphosphorine 2-oxide, 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide, N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphinan-2-amine 2-oxide #, 36341-88-5

ID: 866

InChIKey: HOOWCUZPEFNHDT-ZETCQYMHSA-N
SMILES: C1=C(C=C(C=C1O)O)[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 443586
synonyms found at PubChem are:
(S)-3,5-Dihydroxyphenylglycine, (S)-3,5-DHPG, 162870-29-3, L-3,5-Dihydroxyphenylglycine, S-DHPG, UNII-CF5G2G268A, C8H9NO4, CHEMBL39221, CF5G2G268A, CHEBI:29474, (S)-3,5 DHPG, (2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid, Benzeneacetic acid, alpha-amino-3,5-dihydroxy-, (alphaS)-, CHEBI:75204, amino(3,5-dihydroxyphenyl)acetic acid, Tocris-0342, Tocris-0805, AC1L9EVQ, Lopac-D-3689, C12026, 3,5-Dihydroxy-phenylglycine, Lopac0_000328, 3,5-Dihydroxy-L-phenylglycine, SCHEMBL12648471, (s)-3,5-dihydroxylphenylglycine, CTK8F0556, MolPort-003-983-555, HMS3261A17, HMS3266F22, ZINC968043, Tox21_500328, BDBM50079183, MFCD11044457, AKOS006239507, CCG-204423, DB04228, LP00328, NCGC00015338-01, NCGC00015338-02, NCGC00024545-01, NCGC00024800-01, NCGC00024800-02, NCGC00024800-03, NCGC00024800-04, NCGC00024800-05, NCGC00261013-01, Amino-(3,5-dihydroxy-phenyl)-acetic acid, J516.528H, RT-005713, (2S)-amino(3,5-dihydroxyphenyl)acetic acid, B6459, EU-0100328, (2r)-Amino(3,5-Dihydroxyphenyl)Acetic Acid, (2S)-amino(3,5-dihydroxyphenyl)ethanoic acid, (S)-Amino-(3,5-dihydroxy-phenyl)-acetic acid, D 3689, SR-01000075813, SR-01000597444, Amino-(3,5-dihydroxy-phenyl)-acetic acid(S-DHPG), J-009981, SR-01000075813-1, SR-01000597444-1, UNII-5YR2N37E6D component HOOWCUZPEFNHDT-ZETCQYMHSA-N, L-(3,5-dihydroxyphenyl)glycine, (S)-3,5-dihydroxyphenylglycine zwitterion, (2S)-azaniumyl(3,5-dihydroxyphenyl)acetate

ID: 867

InChIKey: HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3902
synonyms found at PubChem are:
letrozole, 112809-51-5, Femara, 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile, Letrozol, CGS 20267, CGS-20267, Letoval, LETRAZOLE, Femera, Letrozole [USAN:INN], UNII-7LKK855W8I, 4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile, Femara (TN), Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-, LEROZOLE, HSDB 7461, 4-[(4-CYANOPHENYL)(1H-1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE, 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile, C17H11N5, 1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole, CHEMBL1444, Letrozole (JAN/USP/INN), 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile, 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile, 7LKK855W8I, CHEBI:6413, 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile, FEM-345, HPJKCIUCZWXJDR-UHFFFAOYSA-N, MFCD00866241, 4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile, NCGC00016973-01, CAS-112809-51-5, DSSTox_CID_3202, DSSTox_RID_76924, 1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole, DSSTox_GSID_23202, Q-201291, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole, 4-[1-(4-CYANOPHENYL)-1-(1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE, SMR000466343, SR-01000759382, CCRIS 8822, Femara, Letrozole, Letrozole [USAN:USP:INN:BAN], LETROZ, LETROF L LIL, AC1L1GYT, Prestwick0_001025, Prestwick1_001025, Prestwick2_001025, Prestwick3_001025, Femara (TN) (Novartis), D0C1WH, Novartis Brand of Letrozole, SCHEMBL4331, BIDD:PXR0130, BSPBio_001209, MLS000759455, MLS001424038, MLS002584991, MLS006010040, BIDD:GT0015, SPBio_003070, BPBio1_001331, GTPL5209, DTXSID4023202, Letrozole, >=98% (HPLC), BDBM13061, CTK8B5413, EX-A965, QCR-225, 4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile), HMS1571M11, HMS2051E08, HMS2089L22, HMS2098M11, HMS2233C23, HMS3369E11, HMS3393E08, HMS3651K05, HMS3715M11, Pharmakon1600-01502354, BCP23354, CGS-20267 pound>>LETROZOLE, CGS20267, KS-00000XA8, ZINC3778874, Tox21_110719, Tox21_303572, ABP001083, ANW-48664, BG0620, NSC719345, NSC759652, s1235, STL451047, AKOS005145822, AB07525, AC-1193, AN-6525, API0024524, BCP9000848, CCG-100849, CS-1776, DB01006, KS-1269, NC00099, NSC-719345, NSC-759652, RP29922, RTC-070977, NCGC00016973-02, NCGC00016973-03, NCGC00016973-06, NCGC00257460-01, 4CA-0737, AJ-45577, BC205693, BR-59607, CPD000466343, HY-14248, LS-38788, SAM001246649, SC-00402, BCP0726000213, AB0012832, AB1009309, AX8041188, CGS 20267, Femara, Piroxicam, Letrozole, KB-187805, ST2405214, TL8000371, 1-Bis(4-cyanophenyl)methyl-1,2,4-triazole, 4,2,4-Triazol-1-ylmethylene)dibenzonitrile, AB00514009, FT-0627797, L0248, A25380, C08163, D00964, EN300-264820, J10423, S-4137, AB00514009-05, AB00514009-07, AB00514009-08, AB00514009-09, AB00514009_10, AB00514009_11, 809L515, W-60273, 4,4'-(1,2,4-Triazol-1-ylmethylene)dibenzonitrile, I06-0022, SR-01000759382-4, SR-01000759382-5, BRD-K88789588-001-03-2, 4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile, 4,4'-(1,2,4-TRIAZOL-1-YLMETHYL)DIBENZONITRILE, 4,4'-(1h-1,2,4-triazol-1-ylmethylene)-bisbenzonitrile, F2173-0288, Z1741968261, Letrozole, European Pharmacopoeia (EP) Reference Standard, Letrozole, United States Pharmacopeia (USP) Reference Standard, Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material, 4,4 inverted exclamation marka-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile

ID: 868

InChIKey: HPLNTJVXWMJLNJ-XBXARRHUSA-N
SMILES: C1=CC(=CC(=C1)O)/C=C(\C#N)/C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5353398
synonyms found at PubChem are:
alpha-cyano-3-hydroxycinnamic acid, 54673-07-3, 2-Propenoic acid, 2-cyano-3-(3-hydroxyphenyl)-, .alpha.-Cyano-3-hydroxycinnamic acid, 2-Cyano-3-(3-hydroxyphenyl)acrylic Acid, (2E)-2-cyano-3-(3-hydroxyphenyl)prop-2-enoic acid, Spectrum5_001637, AC1NS45T, BSPBio_003149, MLS002207265, SPECTRUM1502095, AC1Q71L9, SCHEMBL2057244, CHEMBL1496361, HMS502G07, HPLNTJVXWMJLNJ-XBXARRHUSA-N, MolPort-044-724-321, ZINC155097, 6137AH, CCG-39218, SBB057150, AKOS000138797, IDI1_000765, NCGC00095882-01, NCGC00095882-02, alpha-Cyano-3-hydroxybenzenepropenoic acid, CC-23963, SMR001306790, ST50997503, (E)-2-cyano-3-(3-hydroxyphenyl)prop-2-enoic acid, (2E)-2-Cyano-3-(3-hydroxyphenyl)-2-propenoic acid #

ID: 869

InChIKey: HPNSFSBZBAHARI-RUDMXATFSA-N
SMILES: CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(\C)/CCC(=O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 446541
synonyms found at PubChem are:
mycophenolic acid, 24280-93-1, Mycophenolate, Melbex, Myfortic, Mycophenolsaeure, Acido micofenolico, Micofenolico acido, Acide mycophenolique, Acidum mycophenolicum, Lilly-68618, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, CCRIS 5565, NSC 129185, NSC-129185, Mycophenoic acid, UNII-HU9DX48N0T, Ly 68618, Micofenolico acido [Spanish], Acido micofenolico [INN-Spanish], Acide mycophenolique [INN-French], Acidum mycophenolicum [INN-Latin], (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, C17H20O6, EINECS 246-119-3, Lilly 68618, (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, CHEMBL866, HU9DX48N0T, (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid, CHEBI:168396, HPNSFSBZBAHARI-RUDMXATFSA-N, TNP00198, RS-61443 [AS MOFETIL], NSC129185, (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-, 4-Methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide (E)-, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid (E)-, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-, NCGC00016786-01, CAS-24280-93-1, 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, DSSTox_CID_21070, DSSTox_RID_79619, DSSTox_GSID_41070, (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid, 483-60-3, (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid, (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxohydroisobenzofuran-5-yl)-4-methylhex -4-enoic acid, 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid, MOA, SMR000471887, SR-01000597602, Mycophenolsaure, 6-[4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl]-4-methyl-4-hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, Prestwick_817, EINECS 207-595-8, Mycophenolic acid [USAN:BAN:INN], Mycophenolic acid [USAN:INN:BAN], 1185242-90-3, Tocris-1505, (Z)-Mycophenolic Acid, 1jr1, Mycophenolic acid (TN), AC1L9JSG, Prestwick2_000556, Prestwick3_000556, Spectrum5_001654, Mycophenolic Acid (MPA), UPCMLD-DP028, 4-Hexenoic acid, (E)-, EC 246-119-3, AC1Q6HP2, SCHEMBL4549, Mycophenolic (Mycophenolate), Mycophenolic acid, >=98%, BSPBio_000631, BSPBio_002534, MLS001074701, MLS002222265, MLS002695945, BIDD:GT0456, SPECTRUM1500674, BPBio1_000695, GTPL6832, MEGxm0_000120, Mycophenolic acid (USAN/INN), Myfortic (mycophenolate sodium), SCHEMBL2514376, ZINC1758, DTXSID4041070, UPCMLD-DP028:001, ACon0_000960, ACon1_000496, BDBM19264, CHEBI:92545, HMS500H08, AOB5506, EX-A975, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid, MolPort-001-732-316, HMS1569P13, HMS1921A18, HMS2089A17, HMS2092G22, HMS2096P13, HMS2268H22, HMS3403P09, Pharmakon1600-01500674, ACT02623, BCP05321, HY-B0421, Tox21_110610, BBL034696, CCG-39914, MFCD00036814, NSC757424, s2487, STL419986, Mycophenolic acid, analytical standard, AKOS015888214, Tox21_110610_1, AC-4491, AN-7044, API0024821, BCP9000970, CS-2527, DB01024, DS-1638, MCULE-1991681277, NSC-757424, SDCCGMLS-0066618.P001, IDI1_000146, NCGC00016786-02, NCGC00016786-03, NCGC00016786-04, NCGC00016786-05, NCGC00016786-06, NCGC00016786-07, NCGC00016786-08, NCGC00016786-09, NCGC00016786-10, NCGC00016786-11, NCGC00016786-12, NCGC00016786-15, NCGC00025190-01, NCGC00025190-02, NCGC00025190-03, NCGC00025190-04, NCGC00025190-05, NCGC00025190-07, NCGC00025190-08, NCGC00025190-09, NCGC00025190-10, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-, 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methylhex-4-enoic acid, AJ-08079, BC218915, BR-34309, LS-75578, SC-14135, ST044516, SBI-0051945.P003, AB0011511, AB2000593, ST2418864, A-249, M2216, C20380, D05096, EN300-122327, M 5255, M-1202, AB00052466-13, AB00052466-14, AB00052466_15, AB00052466_16, 280M931, I01-0943, SR-01000597602-1, SR-01000597602-3, SR-01000597602-4, BRD-K63750851-001-06-6, BRD-K63750851-001-13-2, Mycophenolic acid, powder, BioReagent, suitable for cell culture, >=98%, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthanlanyl)-4-methyl-4-hexanoic acid, (4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid (Mycophenolic Acid), (E)-6-(1,3-dihydro-4-hydroxy-6- methoxy-7-methyl-3-oxoisobenzofuran-5-yl)-4-methyl-4-hexenoic acid, (E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxoisobenzofuran-5-yl)-4-methyl-4-hexenoic acid, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (9CI), 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)- (8CI), 4-Hexenoic acid,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5- isobenzofuranyl)-4-methyl-, (E)-, 4-Methyl-6-[3-oxo-7-methyl-4-hydroxy-6-methoxy-1,3-dihydroisobenzofuran-5-yl]-4-hexenoic acid, E-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid

ID: 870

InChIKey: HPSILLNWMJOWNM-UJMOMDHXSA-N
SMILES: CCC(C)C(=O)O[C@@H]1C[C@]2([C@@H](OC(=O)CC23[C@]45[C@]1([C@@]6([C@H](C7(CC6([C@@]([C@H]4OC(=O)C)(C7OC(=O)C8(C(O8)C)C)O)O)C)CC(=O)OC)C)OC(O5)(O3)C)C9=COC=C9)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708545
synonyms found at PubChem are:
Utilin, CHEMBL3039300, KBio1_001127, Spectrum_000574, SpecPlus_000087, Spectrum2_000246, Spectrum3_000027, Spectrum4_001307, Spectrum5_000093, BSPBio_001693, KBioGR_001713, KBioSS_001054, SPECTRUM100081, DivK1c_006183, SPBio_000032, KBio2_001054, KBio2_003622, KBio2_006190, KBio3_000813, BDBM50442889, CCG-39807, SDCCGMLS-0066284.P001, NCGC00179082-01, SR-05000002782, SR-05000002782-1

ID: 871

InChIKey: HQFWVSGBVLEQGA-UHFFFAOYSA-N
SMILES: CCCCN(CCCC)CCCOC(=O)C1=CC=C(C=C1)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2480
synonyms found at PubChem are:
butacaine, 149-16-6, 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate (ester), Butacaine [INN:BAN], p-Aminobenzoyldibutylaminopropanol, Butacainum [INN-Latin], Butacaina [INN-Spanish], UNII-Z84S23CGJJ, 3-Dibutylaminopropyl p-aminobenzoate, Butelline, Butyn, 3-(Dibutylamino)propyl 4-aminobenzoate, Butacaine sulphate, 3-(Dibutylamino)-1-propanol p-aminobenzoate, C18H30N2O2, 3-(p-Aminobenzoxy)-1-di-n-butylaminopropane, EINECS 205-734-7, BRN 2135378, Z84S23CGJJ, MLS000028619, NCGC00016411-01, CAS-149-16-6, SMR000058686, 1-PROPANOL, 3-(DIBUTYLAMINO)-, p-AMINOBENZOATE (ESTER), DSSTox_CID_25300, DSSTox_RID_80789, DSSTox_GSID_45300, Butacainum, Butacaina, SR-01000003139, Prestwick_984, Spectrum_001562, AC1L1DRW, AC1Q2WTH, Opera_ID_1473, Prestwick0_000831, Prestwick1_000831, Prestwick2_000831, Prestwick3_000831, Spectrum2_001593, Spectrum3_001943, Spectrum4_000219, Spectrum5_001565, D06ORU, SCHEMBL26156, BSPBio_000781, BSPBio_003543, KBioGR_000857, KBioSS_002042, DivK1c_000864, SPECTRUM1503914, SPBio_001586, SPBio_002702, BPBio1_000861, CHEMBL129529, DTXSID3045300, CHEBI:94820, CTK8F8367, HMS502L06, KBio1_000864, KBio2_002042, KBio2_004610, KBio2_007178, KBio3_002827, HQFWVSGBVLEQGA-UHFFFAOYSA-N, MolPort-001-846-213, NINDS_000864, HMS1570H03, HMS1922K10, HMS2093K17, HMS2097H03, HMS2230J20, HMS3371O14, HMS3714H03, Pharmakon1600-01503914, HY-B1007, ZINC1596184, Tox21_110428, 2290AH, CCG-39371, NSC758632, AKOS024374899, Tox21_110428_1, API0015124, CS-4504, MCULE-4554935124, NSC-758632, IDI1_000864, NCGC00016411-02, NCGC00016411-03, NCGC00016411-04, NCGC00016411-05, NCGC00016411-06, NCGC00016411-07, NCGC00016411-10, NCGC00023714-03, NCGC00023714-04, NCGC00023714-05, 3-(Dibutylamino)propyl 4-aminobenzoate #, AN-23299, (3-di-N-Butylaminopropyl)-p-aminobenzoate, SBI-0051856.P002, LS-122041, AB00052382, ST51014906, 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate, 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate, 4-aminobenzoic acid 3-(dibutylamino)propyl ester, AB00052382_15, AB00052382_16, J-008557, J-008559, SR-01000003139-2, SR-01000003139-3, BRD-K99622919-001-05-7, BRD-K99622919-001-15-6

ID: 872

InChIKey: HQKQRXZEXPXXIG-NTIOYTNASA-N
SMILES: C[C@@H]1CCC2[C@]13CC[C@@](C(C3)C2(C)C)(C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 9838172
synonyms found at PubChem are:
cedryl-acetate

ID: 873

InChIKey: HQNGOCGBIGVSGF-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)NC2=NC3=CC=CC=C3C(=C2)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"E Caci" "O Zegarra-Moran" "LJ Galietta" "GL Lukacs" "K Du" "AS Verkman" "N Pedemonte"

CID is 747013
synonyms found at PubChem are:
(4-Methyl-quinolin-2-yl)-p-tolyl-amine, 4-methyl-N-(4-methylphenyl)quinolin-2-amine, CBMicro_024252, AC1LF53B, MixCom6_001276, Oprea1_019134, Oprea1_601484, SCHEMBL837706, MolPort-001-932-877, HMS1613G22, ZINC191182, CCG-11399, STL383350, AKOS000631231, MCULE-2719777287, BAS 00437680, BIM-0024146.P001, EU-0078385, SR-01000493924, SR-01000493924-1

ID: 874

InChIKey: HQVZOORKDNCGCK-UHFFFAOYSA-N
SMILES: CC(C)(C)CC(C)(C)C1=CC(=C(C=C1)O)CC2=C(C=C(C=C2)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2799
synonyms found at PubChem are:
clofoctol, 37693-01-9, Octofene, Clofoctolum, Clofoctol [INN], Clofoctolum [INN-Latin], C21H26Cl2O, UNII-704083NI0R, EINECS 253-632-6, BRN 2478182, 2-((2,4-Dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol, Clofoctol (INN), 704083NI0R, NCGC00095016-01, 2-(2,4-Dichlorobenzyl)-4-(1,1,3,3-tetramethylbutyl)phenol, alpha-(2,4-Dichlorophenyl)-4-(1,1,3,3-tetramethylbutyl)-o-cresol, 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol, Phenol, 2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-, DSSTox_CID_25889, DSSTox_RID_81203, DSSTox_GSID_45889, 2-[2,4-Dichlorobenzyl]-4-[1,1,3,3-tetramethylbutyl]phenol, 2-(2,4-dichlorobenzyl)-4-(2,4,4-trimethylpentan-2-yl)phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)phenol, CAS-37693-01-9, Clofoctolo, Gramplus, Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-, Octofene (TN), Spectrum_001533, AC1L1EHT, Spectrum2_001533, Spectrum3_001565, Spectrum4_000161, Spectrum5_001082, D00NJL, BSPBio_003070, KBioGR_000641, KBioSS_002013, MLS002207309, Clofoctol, analytical standard, DivK1c_000426, SCHEMBL147809, SPECTRUM1503206, SPBio_001346, CHEMBL1476605, DTXSID5045889, CTK6G7999, HMS501F08, KBio1_000426, KBio2_002013, KBio2_004581, KBio2_007149, KBio3_002570, CHEBI:108581, HQVZOORKDNCGCK-UHFFFAOYSA-N, MolPort-003-940-676, NINDS_000426, HMS1922I09, Pharmakon1600-01503206, HY-B1150, ZINC2149829, Tox21_111389, 2329AH, CCG-39311, NSC758389, AKOS024374914, Tox21_111389_1, CS-4755, MCULE-3939000404, NSC-758389, ACM37693019, IDI1_000426, NCGC00095016-02, NCGC00095016-03, NCGC00095016-05, CJ-33098, SMR001306814, SBI-0051786.P002, LS-104344, FT-0704662, ST51014944, D07244, AB00052326_04, AB00052326_05, C-56242, SR-01000872766, SR-01000872766-1, BRD-K02900412-001-04-8, BRD-K02900412-001-05-5, BRD-K02900412-001-07-1, 2-(2,4-Dichlorobenzyl)-4-(1,1,3,3-tetramethylbutyl)phenol #, .alpha.-(2,4-Dichlorophenyl)-4-(1,1,3,3-tetramethylbutyl)-o-cresol, Octophene(2,4-dichlorobenzyl)-2(1,1,3,3-tetramethyl-butyl)- 4-phenol

ID: 875

InChIKey: HRICZKVMTVXKFQ-UHFFFAOYSA-N
SMILES: CCCN1C(=O)C2=CC=CC=C2N=C1C(C)N3CCN(CC3)S(=O)(=O)C4=CC=C(C=C4)Br

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"J González" "J Rader" "M Miller" "F Van Goor" "E Olson" "PD Grootenhuis" "JH Stack" "T Knapp" "A Hazlewood" "D Cao" "R Tung" "T Neuberger" "J Joubran" "V Panchenko" "LR Makings" "S Hadida" "A Singh" "KS Straley" "P Negulescu"

CID is 11957830
synonyms found at PubChem are:
SCHEMBL3824460, HRICZKVMTVXKFQ-UHFFFAOYSA-N, 2-{1-[4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-ethyl}-3-propyl-3H-quinazolin-4-one

ID: 876

InChIKey: HRIQFVCFOPJYEQ-UHFFFAOYSA-N
SMILES: CNCC(C1=CC(=C(C=C1)O)OC)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 102502
synonyms found at PubChem are:
881-95-8, 4-(1-Hydroxy-2-(methylamino)ethyl)-2-methoxyphenol hydrochloride, Metanephrine hydrochloride, (+-)-Metanephrine hydrochloride, (+/-)-Metanephrine hydrochloride, EINECS 212-922-2, 5090-31-3, Adrenaline, 3-methoxy-, hydrochloride, Metanephrine hydrochloride DL, Dl-m-O-methylepinephrine hydrochloride, (+-)-4-Hydroxy-3-methoxy-alpha-((methylamino)methyl)benzenemethanol hydrochloride, D,L-Metanephrine hydrochloride, (+-)-alpha-((Methylamino)methyl)vanillyl alcohol hydrochloride, 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol;hydrochloride, Metanephrine HCl, Benzenemethanol, 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-, 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride, Prestwick_906, EINECS 225-809-8, alpha-((Methylamino)methyl)vanillyl alcohol hydrochloride, AC1L2SXI, Metadrenaline Hydrochloride, AC1Q3F7G, SCHEMBL2471378, 3-Methoxyadrenaline Hydrochloride, CTK8C4416, Metanephrine hydrochloride, 99%, HRIQFVCFOPJYEQ-UHFFFAOYSA-N, HMS1568I06, rac Metanephrine Hydrochloride Salt, 3-O-Methylepinephrine Hydrochloride, BCP27969, DL-O-Methylepinephrine hydrochloride, 4061AC, ANW-71821, AKOS016007304, MCULE-8659424675, AK-67845, AN-47917, LS-30766, AX8159608, ST2405304, TC-160566, 4CH-017377, FT-0648745, ST50319995, D,L-Metanephrine hydrochloride, >=98% (HPLC), 881O958, ( inverted exclamation markA)-Metanephrine Hydrochloride, 4-(1-Hydroxy-2-(methylamino)ethyl)-2-methoxyphenol HCl, 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol, chloride, Vanillyl alcohol, alpha-((methylamino)methyl)-, hydrochloride, 4-(1-Hydroxy-2-(methylamino)ethyl)-2-methoxyphenolhydrochloride, 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxy-phenol hydrochloride, Vanillyl alcohol, alpha-((methylamino)methyl)-, hydrochloride (8CI), 4-Hydroxy-3-methoxy-|A-[(methylamino)methyl]benzenemethanol Hydrochloride

ID: 877

InChIKey: HRYJPHOTGFERGT-UHFFFAOYSA-N
SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=NC=CC=N2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6136
synonyms found at PubChem are:
THONZYLAMINE HYDROCHLORIDE, Thonzylamine HCl, 63-56-9, Novohetramin, Anahist, Resistab, Thonzylaminium chloride, Neohetramine hydrochloride, UNII-6K9YKD48Y4, CCRIS 6277, Thonzylamine hydrochloride [USAN], EINECS 200-561-3, NH 188, 6K9YKD48Y4, 2-[(2-dimethylaminoethyl)(p-methoxybenzyl)amino]pyrimidine hydrochloride, NCGC00095010-01, DSSTox_CID_6147, 2-((2-(Dimethylamino)ethyl)(p-methoxy-benzyl)amino)-pyrimidine hydrochloride, N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyrimidyl)ethylenediamine hydrochloride, N-p-Methoxybenzyl-N',N'-dimethyl-N-2-pyrimidinylethylene diamine hydrochloride, DSSTox_RID_78035, DSSTox_GSID_26147, C16H22N4O, 2- (2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino pyrimidine hydrochloride, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine hydrochloride, CAS-63-56-9, Pyrimidine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-, hydrochloride, 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyrimidinyl-, monohydrochloride, 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyrimidinyl-, monohydrochloride, 2-{(2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino}pyrimidine hydrochloride, N-(4-methoxybenzyl)-N-(2-(dimethylamino)ethyl)pyrimidin-2-amine, Super anahist (TN), AC1L1LVI, AC1Q3CNG, SCHEMBL29417, 91-85-0 (Parent), SPECTRUM1503135, CHEMBL1529802, DTXSID8026147, CHEBI:32219, CTK5H0563, HRYJPHOTGFERGT-UHFFFAOYSA-N, HMS1922G17, Pharmakon1600-01503135, BCP07457, Tox21_111387, LS-273, NSC758388, Tox21_111387_1, CCG-213118, NSC-758388, Thonzylamine hydrochloride (JAN/USAN), NCGC00095010-02, NCGC00178145-03, D01801, N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyrimidin-2-ylethane-1,2-diamine hydrochloride, N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine hydrochloride, N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine;hydrochloride

ID: 878

InChIKey: HSDSBIUUVWRHTM-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)NC2=CC=C(C=C2)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 3846708
synonyms found at PubChem are:
54381-08-7, HC orange No 1, HC Orange 1, 4-((2-Nitrophenyl)amino)phenol, HC Orange no. 1, 4-(2-nitroanilino)phenol, 4-(2-nitroanilino)benzenol, p-((o-Nitrophenyl)amino)phenol, 4-hydroxy-2'-nitrodiphenylamine, UNII-Z92U49184U, 2-Nitro-4'-hydroxydiphenylamine, 4-[(2-nitrophenyl)amino]phenol, EINECS 259-132-4, Phenol, 4-((2-nitrophenyl)amino)-, Phenol, 4-[(2-nitrophenyl)amino]-, Z92U49184U, W-105634, HC Orange No.1, AC1MZEBU, 4-(2-nitrophenylamino)phenol, MLS000736169, SCHEMBL109703, CHEMBL1339868, DTXSID0068949, 4'-hydroxy-2-nitro-diphenylamine, MolPort-002-888-013, REGID_for_CID_3846708, 4-[(2-Nitrophenyl)amino]-phenol, KS-000028EQ, ZINC4054876, AKOS015915469, MCULE-2341723302, MS-3693, NCGC00246574-01, AN-40578, KB-52353, SMR000338719, U586, LS-104995, FT-0602544, ST24042371, A830141, SR-01000310185, I14-6372, SR-01000310185-1

ID: 879

InChIKey: HSHGZXNAXBPPDL-HZGVNTEJSA-N
SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)N)SC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441328
synonyms found at PubChem are:
7-Aminocephalosporanic acid, 957-68-6, 7-ACA, 7-Aminocephalosporinic acid, 7beta-Aminocephalosporanic acid, 7-ACS, UNII-9XI67897RG, CHEBI:2255, (7R)-7-aminocephalosporanic acid, (7R)-7-Aminocephalosporanate, Cephalosporanic acid, 7-amino, (6R,7R)-3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 9XI67897RG, DSSTox_CID_25342, DSSTox_RID_80810, DSSTox_GSID_45342, (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-(acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, CHEMBL1615585, NCGC00016552-01, CAS-957-68-6, Prestwick_714, EINECS 213-485-0, PubChem24166, AC1L9AZG, Prestwick0_000424, Prestwick1_000424, Prestwick2_000424, Prestwick3_000424, Epitope ID:120362, EC 213-485-0, 7-amino cephalosporanic acid, SCHEMBL78638, BSPBio_000408, 7|A-aminocephalosporanic acid, SPBio_002347, BPBio1_000450, 7beta-amino-cephalosporanic acid, DTXSID9045342, 7-Aminocephalosporanic Acid,(S), 7-beta-aminocephalosporanic acid;, HSHGZXNAXBPPDL-HZGVNTEJSA-N, MolPort-001-794-514, 7-Aminocephalosporanic acid, 98%, HMS1569E10, HMS2096E10, HMS3713E10, (7R)-7-amino-cephalosporanic acid, BCP22888, EBD18443, HY-B1434, ZINC3861379, 7-AMINO-CEPHALOSPORANIC ACID, Tox21_110490, MFCD00005177, s2530, AKOS015951379, Tox21_110490_1, CCG-220424, CS-4823, RL06058, SMP2_000203, 7-Aminocephalosporanic acid;957-68-6, NCGC00179570-01, NCGC00179570-03, NCGC00263474-01, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-, AC-24181, AJ-46181, AS-15727, BC682290, Q448, SY012906, (6R,7R)-3-(acetoxymethyl)-7-amino-8-, AB0017588, AB1009533, B1652, FT-0621351, ST24045579, oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-, C07756, J10226, M-1429, 957A686, BRD-K65377893-001-01-7, 3-Acetoxymethyl-7beta-aminoceph-3-em-4-carboxylic acid, 7beta-amino-3-acetoxymethyl-3-cephem-4-carboxylic acid, (6R,7R)-3-acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid, 3-acetoxymethyl-7beta-amino-3,4-didehydrocepham-4-carboxylic acid, 7-Aminocephalosporanic acid, Antibiotic for Culture Media Use Only, 3-Acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, (6R,7R)-3-(acetoxymethyl)-7-amino-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-(acetyloxymethyl)-7-azanyl-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (7-ACA), 13256-42-3, 23241-25-0, 26328-10-9, 4KR, 70035-93-7, 856652-38-5, 856652-39-6, AC1OEJW1, (7R)-7 aminocephalosporanate, SCHEMBL10364275, CHEBI:58501, 7beta-aminocephalosporanic acid zwitterion, A845463, (6R)-3-(acetoxymethyl)-7-ammonio-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-3-(acetyloxymethyl)-7-ammonio-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-3-(acetyloxymethyl)-7-azaniumyl-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-3-(acetyloxymethyl)-7-azaniumyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

ID: 880

InChIKey: HSHNITRMYYLLCV-UHFFFAOYSA-N
SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5280567
synonyms found at PubChem are:
4-methylumbelliferone, 90-33-5, Hymecromone, 7-HYDROXY-4-METHYLCOUMARIN, 7-Hydroxy-4-methyl-2H-chromen-2-one, Imecromone, beta-Methylumbelliferone, Cholestil, Mendiaxon, 4-Methyl-7-hydroxycoumarin, Bilcolic, Bilicante, Cantabilin, Coumarin 4, Cantabiline, Cholonerton, Hymecromon, Crodimon, Eurogale, Medilla, Cumarote-C, 4-MU, Resocyanine, 4-Methylumbelliferon, 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-, Omega 127, Pilot 447, Himecromona, Hymecromonum, 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran, Imecromone [DCIT], LM 94, NSC 9408, NSC 19026, Cholspasmin, Coumarin, 7-hydroxy-4-methyl-, 7-hydroxy-4-methylchromen-2-one, Hymecromonum [INN-Latin], Himecromona [INN-Spanish], 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one, 2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-, 2H-1-Benzopyren-2-one, 7-hydroxy-4-methyl-, 4-Methylumbelliferon [Czech], 7-Hydroxy-4-methyl-2-oxo-3-chromene, UNII-3T5NG4Q468, 4-Methylumbelliferone (4-MU), CCRIS 5926, NSC9408, LM-94, 7-hydroxy-4-methyl-chromen-2-one, NSC19026, EINECS 201-986-7, .beta.-Methylumbelliferone, BRN 0142217, 7-hydroxy-4-methyl coumarin, 4-Methyl-7-hydroxy-coumarin, CHEMBL12208, AI3-08085, 2H-1-Benzopyran-2-one,7-hydroxy-4-methyl-, CHEBI:17224, HSHNITRMYYLLCV-UHFFFAOYSA-N, 3T5NG4Q468, CAS-90-33-5, NCGC00016345-01, DSSTox_CID_5670, DSSTox_RID_77877, DSSTox_GSID_25670, METHYLUMBELLIFERONE, BETA, WLN: T66 BOVJ E1 IQ, SMR000471886, 4 Methylumbelliferone, 7-hydroxy-4-methyl-coumarin, Hymechrome, Himecol, Hymecromone [USAN:INN:JAN], Biliton H, Hymecromohe,(S), Cantabiline (TN), 4MU, Hymecromone [USAN:INN:BAN:JAN], 4-methyl umbelliferone, 4-Methyl-umbelliferone, bet.-Methylumbelliferone, Coumarin derivative, 3b, AC1NQX8G, AC1Q2HEE, Maybridge1_002078, Prestwick0_000901, Prestwick1_000901, Prestwick2_000901, Prestwick3_000901, Umbelliferone, 4-methyl-, 7-Hydroxy-4-methlcoumarin, Methylumbelliferone, .beta., 7-hydroxy-4-methyl-coumari, SCHEMBL24150, BSPBio_000742, 5-18-01-00439 (Beilstein Handbook Reference), 7-hydroxy-4-methyl coumarine, KSC498C0B, MLS001074671, MLS004491718, 4-Methyl-7-hydroxyl Coumarin, SPBio_002941, 4-Methylumbelliferone - 4-MU, AMBZ0098, BPBio1_000818, MEGxp0_001898, 4-Methylumbelliferone, >=98%, DTXSID8025670, ACon1_002401, cid_5280567, CTK2G4039, CTK3J8100, HMS547G10, Hymecromone (JP17/USAN/INN), ZINC58121, MolPort-000-467-367, HMS1570F04, HMS2097F04, HMS2267L19, HMS3264E04, HMS3655L16, HMS3714F04, Pharmakon1600-01506174, 4-methyl-7-oxidanyl-chromen-2-one, BCP06770, HY-N0187, KS-00000JR8, NSC-9408, Tox21_110385, Tox21_300915, ANW-43852, BBL000531, BDBM50022178, CCG-47894, MFCD00006866, NSC-19026, NSC760397, s2256, SBB009085, STK364326, 7-Hydroxy-4-methyl-2H-2-chromenone, AKOS000119370, AKOS030559698, Tox21_110385_1, AM85958, CS-7560, DB07118, LS-1910, MCULE-3913656430, NSC-760397, RTR-028404, 4-methylumbelliferone;4-MU;90-33-5, 7-hydroxy-4-methyl-1-benzopyran-2-one, 7-Hydroxy-4-methyl-2-oxo-2H-chromene, Hymecromone(7-Hydroxy-4-methylcoumarin), NCGC00016345-02, NCGC00016345-03, NCGC00016345-04, NCGC00016345-05, NCGC00016345-08, NCGC00016345-09, NCGC00169880-01, NCGC00169880-02, NCGC00257522-01, 7-Hydroxy-4-methyl-2H-chromen-2-one #, 7-Hydroxy-4-methylcoumarin, 97% 50g, AC-22306, AN-24191, AS-13247, BR-72865, CJ-00489, H721, KB-74169, NCI60_042099, SC-25664, ZB002323, DB-029370, TL8005812, TR-028404, 2-Hydroxy-4-methyl-7H-1-benzopyran-7-one, AB00443536, B6001, FT-0602257, FT-0658701, FT-0660634, M0453, ST50102505, 7H-1-Benzopyran-7-one, 2-hydroxy-4-methyl-, A-8711, C03081, D00170, M-5410, AB00443536_08, A843515, SR-01000637483, I14-1654, I14-8192, SR-01000637483-1, SR-01000637483-3, BRD-K46424862-001-02-6, BRD-K46424862-001-04-2, F0849-0318, F1918-0038, 56275-29-7, 79566-13-5

ID: 881

InChIKey: HSMNQINEKMPTIC-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=O)NCC(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2148
synonyms found at PubChem are:
4-Aminohippuric acid, aminohippuric acid, 61-78-9, P-AMINOHIPPURIC ACID, Paha, Glycine, N-(4-aminobenzoyl)-, N-(4-Aminobenzoyl)glycine, para-Aminohippuric acid, Nefrotest, N-(p-Aminobenzoyl)glycine, p-Aminohippurate, 2-(4-aminobenzamido)acetic acid, Aminohippurate, PAH (amino acid), N-(para-aminobenzoyl)glycine, Hippuric acid, p-amino-, Aminohippurate sodium, 4-Amino hippuric acid, N-(p-Aminobenzoyl)aminoacetic acid, para-Aminohippurate, paraaminohippuric acid, PAH, UNII-Y79XT83BJ9, NSC 13064, 2-[(4-aminophenyl)formamido]acetic acid, HSDB 2139, 4-Aminobenzoyl Glycine, EINECS 200-518-9, Aminohippuric acid [USP], N-[p-Aminobenzoyl]glycine, 2-[(4-aminobenzoyl)amino]acetic acid, AI3-52275, N-(4-Aminobenzoyl-d4)glycine, Y79XT83BJ9, CHEBI:104011, N-[(4-aminophenyl)carbonyl]glycine, 4-Aminohippurate, CAS-61-78-9, NCGC00016279-01, Aminohippuric acid (USP), DSSTox_CID_2590, DSSTox_RID_76648, DSSTox_GSID_22590, 94-16-6, N-(p-Aminobenzoyl)aminoacetate, 2-[(4-aminophenyl)carbonylamino]acetic acid, SR-05000002048, Aminohippuric acid [USAN], AminohippuratH, p-amino-hippuricaci, PAHH, 4-Aminohippuric acidH, Spectrum_001310, (p-Aminobenzoyl)glycine, (4-aminobenzoyl)glycine, Prestwick0_000895, Prestwick1_000895, Prestwick2_000895, Prestwick3_000895, Spectrum2_001515, Spectrum3_000952, Spectrum4_001065, Spectrum5_001100, ACMC-1AY8I, CHEMBL463, D04DLM, p-AMINOBENZOYLGLYCINE, N-(4-Aminobenzoyl)glycinH, AC1Q51TG, Oprea1_490712, BSPBio_000710, KBioGR_001390, KBioSS_001790, MLS002154055, DivK1c_000694, SCHEMBL196513, SPECTRUM1503069, SPBio_001589, SPBio_002919, AC1L1D10, BPBio1_000782, GTPL4810, p-Aminohippuric acid, >=99%, 2-(4-Aminobenzamido)aceticacid, DTXSID7022590, (4-Aminobenzoylamino)acetic acid, CTK3I9687, HMS502C16, KBio1_000694, KBio2_001790, KBio2_004358, KBio2_006926, KBio3_002044, KS-00000YBH, Hippuric acid, p-amino- (8CI), NSC7550, HSMNQINEKMPTIC-UHFFFAOYSA-N, MolPort-001-792-130, NINDS_000694, HMS1570D12, HMS1922C07, HMS2092H18, HMS2097D12, HMS2233A21, HMS3373E19, HMS3651L04, HMS3714D12, Pharmakon1600-01503069, ZINC119344, ALBB-025851, BCP04299, HY-B1306, NSC-7550, NSC13064, 4-AMINOHIPPURIC ACID BIOTECH, Tox21_110345, ANW-33944, BBL027666, CCG-39181, MFCD00007890, NSC-13064, NSC758232, s2883, SBB000329, STK801822, [(4-Aminobenzoyl)amino]acetic acid #, AKOS000120722, Tox21_110345_1, CS-4816, DB00345, MCULE-9532170257, NSC-758232, RTR-021250, VZ28181, IDI1_000694, p-Aminohippuric acid, >=98.0% (T), NCGC00016279-02, NCGC00016279-03, NCGC00016279-05, NCGC00094993-01, NCGC00094993-02, AC-29237, AJ-11567, AN-23719, KB-36524, SMR001233372, SBI-0051760.P002, DB-053989, LS-168886, ST2416094, TR-021250, A0313, AB00052309, FT-0617576, FT-0622289, R1187, ST45029013, X6859, D06890, AB00052309_08, SR-05000002048-1, SR-05000002048-3, W-203306, I14-19340, Z1270312078, Aminohippuric acid, United States Pharmacopeia (USP) Reference Standard, InChI=1/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13

ID: 882

InChIKey: HSMPDPBYAYSOBC-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(C3=C(C(=C2O1)OC)OC=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3828
synonyms found at PubChem are:
khellin, 82-02-0, Visammin, Amicardine, Methafrone, Coronin, Amikellin, Ammipuran, Ammivisnagen, Benecardin, Corafurone, Gynokhellan, Medekellin, Viscardan, Kelourin, Rykellin, Interkhellin, Ammispasmin, Deltoside, Interkellin, Kalangin, Kelicorin, Kelincor, Khelangin, Khellamine, Khellanals, Khellinorm, Visammimix, Visnagalin, Kelamin, Norkel, Kellosal, Khelfren, Khelisem, Khelloyd, Lynamine, Mefurina, Simeskellina, Vasokellina, Visnagen, Amiptan, Ammivin, Chellin, Kelicor, Kellin, Kellina, Keloid, Eskel, Cardio-khellin, Ammi-khellin, Bi-Kellina, Benekardin, Khelline I, Chellina, Khelline, Ammicardine, Khellinum, Quelina, Chellina [Italian], 5,8-Dimethoxy-2-methyl-6,7-furanochromone, Khellin [INN:DCF], Viscardin, 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one, Khelline [INN-French], Khellinum [INN-Latin], Quelina [INN-Spanish], 5H-Furo[3,2-g][1]benzopyran-5-one, 4,9-dimethoxy-7-methyl-, 5,8-Dimethoxy-2-methyl-4',5'-furo-6,7-chromone, UNII-5G117T0TJZ, IT-033, 5,8-Dimethoxy-2-methyl-4',5'-furano-6,7-chromone, 4,9-Dimethoxy-7-methyl-5-oxo-1,8-dioxabenz-(f)indene, 4,9-Dimethoxy-7-methyl-5-oxofuro(3,2-g)(1)benzopyran, 4,9-Dimethoxy-7-methyl-5-oxofuro(3,2-g)-1,2-chromene, C14H12O5, NSC37744, EINECS 201-392-8, 4,9-Dimethoxy-7-methyl-5H-furo(3,2-g)(1)benzopyran-5-one, NSC 25509, NSC 37744, 5H-Furo(3,2-g)(1)benzopyran-5-one, 4,9-dimethoxy-7-methyl-, BRN 0263185, Chorafurone, Vismagen, Khell, AI3-52114, MLS000028448, 5G117T0TJZ, CHEBI:6133, 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one, NSC8519, HSMPDPBYAYSOBC-UHFFFAOYSA-N, 5,7-furanochromone, CAS-82-02-0, NCGC00016327-01, SMR000058278, 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g]-[1]benzopyran-5-one, 4,2-g][1]benzopyran, 4,8-dioxabenz-[f]indene, 4,2-g]-1,2-chromene, DSSTox_CID_25267, DSSTox_RID_80779, DSSTox_GSID_45267, 5,5'-furo-6,7-chromone, 5,5'-furano-6,7-chromone, 5,9-dimethoxy-2-methylfurano[3,2-g]chromen-4-one, 4,2-g][1]benzopyran-5-one, 5H-Furo[3, 4,9-dimethoxy-7-methyl-, WLN: T C566 DO JV MOJ BO1 HO1 L1, SR-01000000072, 4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g][1]benzopyran, amicardien, 4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g]-1,2-chromene, Gynokhellin, Intercellin, Hkelfren, Prestwick_287, Spectrum_000079, Khellin, for microscopy, Opera_ID_372, Prestwick0_000091, Prestwick1_000091, Prestwick2_000091, Prestwick3_000091, Spectrum2_000593, Spectrum3_000654, Spectrum4_001557, Spectrum5_000154, bmse000751, D0G4KG, AC1L1GT2, SCHEMBL9655, Khellin, analytical standard, BSPBio_000042, BSPBio_002287, KBioGR_002054, KBioSS_000479, SPECTRUM210866, 5-19-06-00320 (Beilstein Handbook Reference), MLS001076533, CHEMBL44746, DivK1c_000046, SPBio_000466, SPBio_001981, AC1Q698Q, BPBio1_000048, MEGxp0_000331, DTXSID9045267, ACon0_000983, ACon1_000350, HMS500C08, HSMPDPBYAYSOBC-UHFFFAOYSA-, KBio1_000046, KBio2_000479, KBio2_003047, KBio2_005615, KBio3_001507, ZINC56654, MolPort-000-724-273, NINDS_000046, HMS1568C04, HMS1923M07, HMS2095C04, HMS2230B16, HMS3371C21, HMS3712C04, Pharmakon1600-00210866, ALBB-025052, KS-000014VM, NSC-8519, NSC25509, Tox21_110374, CCG-36453, LMPK13110001, MFCD00005007, NSC-25509, NSC-37744, NSC755826, SBB072185, AKOS002281934, Tox21_110374_1, API0003088, MCULE-6233012340, NSC-755826, SDCCGMLS-0003040.P003, IDI1_000046, NCGC00016327-02, NCGC00016327-03, NCGC00016327-04, NCGC00016327-05, NCGC00016327-06, NCGC00016327-07, NCGC00016327-08, NCGC00016327-09, NCGC00016327-11, NCGC00023424-03, NCGC00023424-04, NCGC00169160-01, NCGC00169160-02, NCGC00169160-03, 4CN-0721, AS-35307, LS-70711, ST076676, SBI-0051567.P002, FT-0627578, K0039, R1111, W2041, C09010, AB00052134_16, 4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one, 4,9-Dimethoxy-7-methyl-furo[3,2-g]chromen-5-one, SR-01000000072-3, SR-01000000072-4, SR-01000000072-5, SR-01000000072-6, BRD-K80353807-001-05-5, BRD-K80353807-001-06-3, BRD-K80353807-001-16-2, 4,9-Dimethoxy-7-methyl-5-oxo-1,8-dioxabenz[f]indene, 4,9-dimethoxy-7-methylpyrano[3,2-f][1]benzoxol-5-one, 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one #, 5H-Furo[3,2-g][1]benzopyran-5-one,4,9-dimethoxy-7-methyl-, InChI=1/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3

ID: 883

InChIKey: HSQGMTRYSIHDAC-BQBZGAKWSA-N
SMILES: C[C@@H](C(=O)O)NC(=O)[C@H](CC(C)C)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 81721
synonyms found at PubChem are:
L-Leucyl-L-alanine, 7298-84-2, Leu-ala, H-Leu-Ala-OH, (S)-2-((S)-2-Amino-4-methylpentanamido)propanoic acid, Leu-Ala hydrate, Alanine, N-L-leucyl-, L-, CHEMBL541207, CHEBI:73527, L-Alanine, L-leucyl-, L-Alanine, N-L-leucyl-, l-leu-l-ala, Alanine, leucyl-, EINECS 230-737-5, L-Levcyl-L-alanine, NSC 89180, L-Leu-L-Ala-OH, Spectrum2_001499, Spectrum3_001934, L-Leucyl-L-alanineHydrate, AC1L31XN, BSPBio_003534, SCHEMBL259116, SPECTRUM1502207, SPBio_001517, CTK1H0940, KBio3_002789, HSQGMTRYSIHDAC-BQBZGAKWSA-N, MolPort-003-666-420, L-Alanine, N-L-leucyl- (9CI), ZINC1569727, ANW-60563, BDBM50407466, CCG-39171, KM1530, AKOS010366053, L-Leucyl-L-alanine Cell culture grade, KS-0000150N, N-(2-Amino-4-methylpentanoyl)alanine #, NCGC00178004-01, AJ-94582, AK-89691, CC-29994, KB-53302, AX8136542, TC-149308, FT-0627939, L0126, ST24035832, ST50307162, X5370, C-33531, I14-19589, (2S)-2-[(2S)-2-amino-4-methylpentanamido]propanoic acid, (2S)-2-((2S)-2-amino-4-methylpentanoylamino)propanoic acid, (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]propanoic acid, 21369-94-8, L-A

ID: 884

InChIKey: HSRJKNPTNIJEKV-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1OCC(CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3516
synonyms found at PubChem are:
guaifenesin, 93-14-1, Guaiphenesin, GLYCERYL GUAIACOLATE, Glycerol guaiacolate, Guaiphenesine, Guaiacol glyceryl ether, Methphenoxydiol, Aeronesin, Breonesin, Bronchol, Aresol, Propanosedyl, Calmipan, Cortussin, Dorassin, Flartussin, Guaiacuran, Guaiacurane, Guaiamar, Guaianesin, Guaiphesin, Myocaine, Myoscain, Creson, Gaiamar, Hytuss, Myocain, Reduton, Dilyn, Glycerin guaiacolate, Glyceryl guaiacol, Methoxypropanediol, Metossipropandiolo, Metfenossidiolo, Amonidrin, Glycotuss, Guajacuran, Guajamar, Guayanesin, Guiaphenesin, Hustodil, Mintosyl, Miocaina, Miocurin, Miorelax, Mucostop, Muskurelax, Myorelax, Myoscaine, Neuroton, Neurotone, Reorganin, Respenyl, Ritussin, Robitussin, Tenntuss, Glyceryl guaicolate, Glyceryl guiacolate, Guanar, Mucinex, Oresol, Oreson, Respil, Sirotol, Gvaja, Resil, Resyl, Tolyn, Tulyl, Tulyn, 3-(o-Methoxyphenoxy)-1,2-propanediol, Guaiacol glycerol ether, Guaiacolglicerinetere, Guaia-rom, Relaxil G, Relaxyl-G, 3-(2-methoxyphenoxy)propane-1,2-diol, Guaicol glyceryl ether, Gnaifenesin, Guaifenesine, Glyceryl guaiacyl ether, Guaiacyl glyceryl ether, Guaicol glycerine ether, Hustosil, Organidin NR, o-Methoxyphenyl glyceryl ether, Glycero-guaiacol ether, Guaiacol glycerin ether, Guaifenesinum, Amonidren, Pneumomist, 1,2-Propanediol, 3-(2-methoxyphenoxy)-, Trecid, Glycerylguaiacol, 3-(2-Methoxyphenoxy)-1,2-propanediol, Glycerin monoguaiacol ether, Guajacol-glycerinaether, Glyceryl guaiacol ether, 3-o-Methoxyphenoxypropane 1:2-diol, Glyceryl guaiacolate ether, Glycerol mono(2-methoxyphenyl) ether, Equicol, Glycodex, Guiatuss, Actifed C, Guaiacolic acid, ester with glycerol, Colrex expectorant, MY 301, SL-90, XL-90, alpha-Glyceryl guaiacol ether, 1,2-Dihydroxy-3-(2-methoxyphenoxy)propane, Tenntus, alpha-Glyceryl guaiacolate ether, Glycerinmonoguaiacol ether, G 87, 1,2-Propanediol, 3-(o-methoxyphenoxy)-, Benylin-E, Lufyllin-GG, Aether glycerinoguaiacolicus, Glycerol-alpha-guajakolether, Guaifenesine [INN-French], Guaifenesinum [INN-Latin], Guajacol-alpha-glycerinether, Tedral Expectorant, (component of) Deconsal II, Glycerol alpha-guiacyl ether, Guaifenesina [INN-Spanish], MY-301, Glycerol alpha-guaiacyl ether, Tussi-Organidin NR, component of Quibron, 3-(o-Methoxyphenoxy)-propanediol-1,2, component of Hycotuss, Glycerol .alpha.-guiacyl ether, .alpha.-Glyceryl guaiacol ether, Glycerol .alpha.-guaiacyl ether, Guajacol-.alpha.-glycerin-ether, Isoclor Expectorant C, component of Brondecon, Glycerol alpha-monoguaiacol ether, Glycerol-alpha-monoguaiacol ether, Guajacol-glycerinaether [German], Tussi-Organidin-S NR, HSDB 3089, .alpha.-Glyceryl guaiacolate ether, C10H14O4, Glycerol .alpha.-monoguaiacol ether, Glycerol mono(2-methoxyphenyl)ether, component of Quibron Plus, EINECS 202-222-5, Glycerol-alpha-guajakolether [Czech], NSC 62112, 1,2,3-Propanetriol, ether with 2-methoxyphenol, Glycerol alpha-(o-methoxyphenyl)ether, Guaifenesin (Guaiphenesin), Glycerol alpha-(o-methoxyphenyl) ether, Glycerol alpha-(2-methoxyphenyl) ether, BRN 2049375, Glycerol .alpha.-(o-methoxyphenyl)ether, Glycerol .alpha.-(2-methoxyphenyl) ether, AI3-24947, component of Colrex Expectorant, 2-G, 2/G, HSRJKNPTNIJEKV-UHFFFAOYSA-N, NSC62112, 3-[o-Methoxyphenoxy]-1,2-propanediol, GGE, 3-(2-Methoxy-phenoxy)-propane-1,2-diol, DSSTox_CID_3114, (+-)-3-(o-Methoxyphenoxy)-1,2-propanediol, DSSTox_RID_76881, DSSTox_GSID_23114, Fenesin, 1,2-Propanediol, 3-(2-methoxyphenoxy)- (+-)-, W-100252, Guaifenesina, Guaiphenezine, Tussin, Scott-Tussin, SR-01000737186, Halotussin, Genatuss, Glytuss, Glyc, Guaifenesin [USAN:INN:JAN], Uni-tussin, Guaifenesin-d3, Humibid Sprinkle, Actifed-C, Anti-Tuss, Sinumist-SR, Q-Tussin, Guaifenesin,(S), Gee-Gee, CAS-93-14-1, Touro EX, Humibid L.A, NCGC00016350-01, Hustosil (TN), Hytuss-2X, Diabetic Tussin EX, Naldecon Senior EX, Prestwick_231, Balminil Expectorant, Calmylin Expectorant, Entex (Salt/Mix), HUMABID, Dimacol (Salt/Mix), Kwelcof (Salt/Mix), (2R)-3-(2-methoxyphenoxy)propane-1,2-diol, Guaifenesin Dc 95%, Hycotuss (Salt/Mix), Guaifenesin [USAN:USP:INN:BAN:JAN], Brondecon (Salt/Mix), Congestac (Salt/Mix), Triaminic (Salt/Mix), Dilor G (Salt/Mix), PubChem21966, Scot-tussin Expectorant, Spectrum_000835, Pneumomist (Salt/Mix), Q-Tussin (Salt/Mix), Glycerol-a-guajakolether, Mucinex D (Salt/Mix), ROBITUSSIN (TN), Glycerol a-guiacyl ether, Tussar-2 (Salt/Mix), Brexin EX (Salt/Mix), Tussar SF (Salt/Mix), Guaifenesin(Guaiphenesin), a-Glyceryl guaiacol ether, Glycerol a-guaiacyl ether, Mucinex DM (Salt/Mix), Prestwick0_000776, Prestwick1_000776, Prestwick2_000776, Prestwick3_000776, Spectrum2_001104, Spectrum3_000444, Spectrum4_000566, Spectrum5_000758, Lufyllin-GG (Salt/Mix), Naldecon-EX (Salt/Mix), CHEMBL980, Theolair Plus (Salt/Mix), Robitussin CF (Salt/Mix), SCHEMBL4321, a-Glyceryl guaiacolate ether, Neothylline-GG (Salt/Mix), Oprea1_193170, Pneumotussin HC (Salt/Mix), WLN: Q1YQ1OR BO1, 1, 3-(o-methoxyphenoxy)-, Bronkaid Caplets (Salt/Mix), BSPBio_000852, BSPBio_002088, Glycerol a-monoguaiacol ether, KBioGR_000972, KBioSS_001315, Slo-Phyllin GG (Salt/Mix), 4-06-00-05576 (Beilstein Handbook Reference), KSC492I9H, MLS000028402, 1, 3-(2-methoxyphenoxy)-, DivK1c_000248, SPECTRUM1500321, Glycerol-.alpha.-guajakolether, SPBio_001208, SPBio_002791, PV Tussin Tablet (Salt/Mix), Tedral Expectorant (Salt/Mix), AC1L1G42, BPBio1_000938, CHEBI:5551, GTPL7617, Guaifenesin (JP17/USP/INN), DTXSID5023114, Guaiphenesin;Glyceryl guaiacolate, Tussi-Organidin NR (Salt/Mix), CTK3J2493, HMS500M10, KBio1_000248, KBio2_001315, KBio2_003883, KBio2_006451, KBio3_001308, KS-00000KTG, Contac Cough Formula (Salt/Mix), Ru-Tuss DE Tablets (Salt/Mix), Glycerol a-(o-methoxyphenyl)ether, MolPort-001-759-987, NINDS_000248, HMS1570K14, HMS1920B15, HMS2090K20, HMS2091H21, HMS2097K14, HMS2231M20, HMS3369E03, HMS3369N15, HMS3651I17, HMS3714K14, Isoclor Expectorant C (Salt/Mix), Pharmakon1600-01500321, Polaramine Expectorant (Salt/Mix), AC1Q4765, Glycerol a-(2-methoxyphenyl) ether, HY-B0264, ZX-AT008120, Tox21_110389, Tox21_302094, ANW-43892, BBL009981, CCG-39687, NSC-62112, NSC757052, s1740, STK365152, Glycerol, 1-(2-methoxyphenyl) ether, AKOS005435152, Tox21_110389_1, ACN-046918, API0000027, CS-2251, DB00874, KS-5306, MCULE-8909929116, NSC-757052, OR18315, RTR-029185, Guaiacol glyceryl ether, >=98% (GC), IDI1_000248, 3-(2-Methoxyphenoxy)-1, 2-propanediol, NCGC00094689-01, NCGC00094689-02, NCGC00094689-03, NCGC00094689-04, NCGC00094689-06, NCGC00255343-01, AC-26819, AN-24254, K695, KB-69789, SC-18081, SMR000058387, SBI-0051397.P003, AB2000264, LS-120551, LS-120552, TR-029185, AB00052006, FT-0613565, G0159, ST50330628, 1,3-Propanetriol, ether with 2-methoxyphenol, D00337, J10304, 3-(2-Methoxyphenoxy)-1,2-propanediol, 99+%, 3-{[2-(methyloxy)phenyl]oxy}propane-1,2-diol, AB00052006-10, AB00052006-11, AB00052006_12, AB00052006_13, 3 - (2 - Methoxyphenoxy) - 1, 2 - propanediol, I01-6723, SR-01000737186-2, SR-01000737186-3, BRD-A90515964-001-05-8, BRD-A90515964-001-09-0, Guaifenesin, European Pharmacopoeia (EP) Reference Standard, Guaifenesin, United States Pharmacopeia (USP) Reference Standard, Guaifenesin, Pharmaceutical Secondary Standard; Certified Reference Material, 12041-73-5, 128707-44-8, 1336-67-0, InChI=1/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H

ID: 885

InChIKey: HSRMHXWCTRFVHK-NYYWCZLTSA-N
SMILES: COC1=C(C(=CC(=C1)/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)I)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5353685
synonyms found at PubChem are:
I-OMe-Tyrphostin AG 538, I-OMe-AG 538, Tyrphostin I-OMe-AG 538, MLS002153417, SMR001230793, (E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile, alpha-Cyano-(3-methoxy,4-hydroxy,5-iodo)cinnamoyl-(3′,4′-dihydroxyphenyl)ketone, NCGC00016053-01, AC1NS4GH, Lopac-T-7697, Lopac0_001251, CHEMBL1257003, SCHEMBL18045514, SCHEMBL18045517, BDBM60983, CHEBI:92618, cid_5353685, HMS2233K08, HMS3263L04, I-OMe-Tyrphostin AG 538, solid, ZINC3872925, Tox21_501251, HSCI1_000133, IN1975, CCG-205325, LP01251, NCGC00016053-02, NCGC00016053-03, NCGC00016053-04, NCGC00094491-01, NCGC00094491-02, NCGC00261936-01, EU-0101251, T 7697, SR-01000076177, SR-01000076177-1, (E)-3-(4-hydroxy-3-iodo-5-methoxy-phenyl)-2-protocatechuoyl-acrylonitrile, alpha-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3',4'-dihydroxyphenyl)ketone, (E)-2-[(3,4-dihydroxyphenyl)-oxomethyl]-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile, (E)-2-[3,4-bis(oxidanyl)phenyl]carbonyl-3-(3-iodanyl-5-methoxy-4-oxidanyl-phenyl)prop-2-enenitrile

ID: 886

InChIKey: HSTZMXCBWJGKHG-CUYWLFDKSA-N
SMILES: C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281718
synonyms found at PubChem are:
Polydatin, Piceid, 65914-17-2, 27208-80-6, Trans-Piceid, 3,4,5-Trihydroxystilbene-3-beta-monoglucoside, 3,4,5-Tsg, Polydotin Peceid, (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-(4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, Resveratrol 3-beta-mono-D-glucoside, UNII-XM261C37CQ, 5-Tsg, Resveratrol 3-O-beta-glucopyranoside, MLS001424114, CHEBI:8198, XM261C37CQ, 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside, 3,5,4'-Trihydroxystilbene 3-glucoside, 5-Trihydroxystilbene-3-beta-monoglucoside, SMR000466371, 3,4',5-trihydroxystilbene-3-beta-D-glucoside, Pieceid, (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol, (E)-Polydatin, C20H22O8, (E)-Piceid, (2S,3R,4S,5S,6R)-2-(3-hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol, Resveratrol 3-Glucoside, Polydatin (E)-isomer, resveratrol 3-O-beta-D-glucoside, Polydatin(Piceid), Polydatin,(S), Polydatin - Piceid, Polydatin(Piceid)/, AC1NQYYJ, 3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside, Resveratrol 3-O-glucoside, Resveratrol 5-O-glucoside, 3,4',5-TRIHYDROXYSTILBENE-3-BETA-MONOGLUCOSIDE, SCHEMBL41411, trans-Resveratrol C-glucoside, MLS000759499, trans-Resveratrol 3-glucoside, CHEMBL142652, Polydatin(Random Configuration), Resveratrol 3-beta-D-glucoside, trans-Resveratrol 3-O-glucoside, BDBM60919, CHEBI:94610, cid_5281718, HSTZMXCBWJGKHG-CUYWLFDKSA-N, MolPort-003-937-179, MolPort-039-070-121, HMS2051A20, trans-resveratrol 3-beta-glucoside, ZINC4098633, resveratrol-3-O-b-mono-D-glucoside, ABP000698, CP0092, LMPK13090012, Resveratrol 3-O-?-D-glucopyranoside, s2390, trans-resveratrol 3-beta-D-glucoside, AKOS015961013, CCG-100895, DB11263, KS-5384, NC00145, trans-resveratrol 3-O-beta-D-glucoside, NCGC00246971-01, NCGC00246971-04, AJ-48015, AN-15371, AN-38526, AS-13910, CPD000466371, O911, SAM001246720, SC-18338, trans-resveratrol 3-beta-d-glucopyranoside, AB0016722, KB-206626, ST24034112, C10275, AB00639953-07, 3,4',5-Trihydroxystilbene-3-b-D-glucopyranoside, 914P172, Q-100342, W-203441, 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside, 97%, 3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-glucopyranoside, beta-D-Glucopyranoside, 3-hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl, beta-D-Glucopyranoside, 3-hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-, (E)-, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-oxidanyl-phenoxy]oxane-3,4,5-triol, (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-methylol-tetrahydropyran-3,4,5-triol, .beta.-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl3,5,4'-Trihydroxystilbene 3-glucoside, 28759-35-5, 32095-27-5, 58462-72-9

ID: 887

InChIKey: HTEVEFDMFBMFEI-FKLPMGAJSA-N
SMILES: CCC1=CC=CC=C1OC[C@H](CN[C@H]2CCC3=CC=CC=C3C2)O.C(=O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957700
synonyms found at PubChem are:
SR 59230A oxalate, EU-0101131, CHEMBL1324022, HMS3263D03, Tox21_501131, CCG-222435, LP01131, NCGC00094398-01, NCGC00261816-01, S 8688, SR-01000076140, SR-01000076140-1

ID: 888

InChIKey: HUJXGQILHAUCCV-MOROJQBDSA-N
SMILES: CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3NCC4=CC(=CC=C4)I)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 123683
synonyms found at PubChem are:
IB-MECA, 152918-18-8, 3-IB-Meca, piclidenoson, CF-101, N(6)-Ibamu, CF 101, Cf101, N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine, UNII-30679UMI0N, N(6)-(3-Iodobenzyl)adenosine-5'-N-methyluronamide, 1-Deoxy-1-(6-(((3-iodophenyl)methyl)amino)-9H-purin-9-yl)-N-methyl-beta-D-ribofuranuronamide, CHEMBL119709, CHEBI:73286, 30679UMI0N, 3-iodobenzyl-5'-N-methylcarboxamidoadenosine, N(6)-(3-iodo-benzyl)adenosine-5'-N-methyluronamide, (2S,3S,4R,5R)-3,4-dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyloxolane-2-carboxamide, (2S,3S,4R,5R)-5-{6-[(3-iodobenzyl)amino]-9H-purin-9-yl}-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide, beta-D-Ribofuranuronamide, 1-deoxy-1-(6-(((3-iodophenyl)methyl)amo)-9H-purin-9-yl)-N-methyl-, 1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9h-purin-9-yl]-n-methyl-beta-d-ribofuranuronamide, IBMECA, Piclidenoson [USAN], Piclidenoson (USAN/INN), D03VTU, D0Y6ZK, AC1L3X3V, GTPL422, MLS002153391, SCHEMBL465039, REGID_for_CID_123683, CTK8E8477, AOB5361, DTXSID50165158, HUJXGQILHAUCCV-MOROJQBDSA-N, MolPort-003-941-777, HMS2234I04, 3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide, ZINC3811810, BDBM50118812, SI-615, AKOS024456363, API0005162, CS-5048, DB05511, RPR-113090, IB-MECA, solid, >=98% (HPLC), NCGC00024978-02, NCGC00024978-03, NCGC00024978-04, NCGC00024978-05, AN-16662, AS-16876, HY-13591, SC-41757, SMR001230772, LS-184434, RT-013304, D10971, J-008958, N6-(3-iodobenzyl)-5''-N-methylcarboxamidoadenosine, (N-6-(3-iodobenzyl)adenosine-5''-N-methyluronamide, Adenosine, N(6)-[3-iodobenzyl]-4'-methylcarbamoyl-4'-dehydroxymethyl-, N6-(3-Iodobenzyl)adenosine-5 inverted exclamation marka-N-methyluronamide, 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-?-D-ribofuranuronamide, (2R,3R,4S,5S)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide;CF 101, (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide, (2S,3S,4R,5R)-3,4-dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyl-tetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide, (3R,4S,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide, (3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide, 1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-|A-D-ribofuranuronamide, 215462-30-9, b-D-Ribofuranuronamide,1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-

ID: 889

InChIKey: HUKPVYBUJRAUAG-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=CC=CC4=C3C(=CC=C4)C2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6697
synonyms found at PubChem are:
BENZANTHRONE, 82-05-3, 7H-Benz[de]anthracen-7-one, Benzanthrenone, MS-Benzanthrone, 7H-benzo[de]anthracen-7-one, DYE, benzanthrone, Benzoanthrone, Mesobenzanthrone, 1,9-Benzanthrone, 7H-Benz(de)anthracen-7-one, benzo[a]phenalen-7-one, 7-Oxobenz(de)anthracene, 7-Oxobenz[de]anthracene, 1,9-Benz-10-anthrone, Naphthanthrone (VAN), 7H-Benz(de)anthracene-7-one, 7H-Benzo(de)anthracen-7-one, UNII-LP5P3RR8QN, NSC 5189, NSC 631641, CCRIS 3173, HSDB 5245, benz[de]anthracen-7-one, Benz(de)anthracen-7-one, EINECS 201-393-3, LP5P3RR8QN, HUKPVYBUJRAUAG-UHFFFAOYSA-N, NSC631641, 7H-Benz[de]anthracene-7-one, W-104190, naphtanthrone, 7-benzo[a]phenalenone, AC1Q6DQD, AC1Q6NKX, Spectrum2_000766, Spectrum3_001680, AC1L1N3P, SCHEMBL23838, BSPBio_003499, MLS002207268, SPECTRUM1505272, SPBio_000812, ACMC-20977j, CHEMBL1607517, DTXSID8052566, CHEBI:93350, CTK3E8594, KBio3_002719, KS-00000UEF, NSC5189, MolPort-000-557-972, NSC-5189, ZINC3860207, 7H-Benz[de]anthracen-7-one, 98%, ANW-13613, CCG-38994, SBB057877, STK662686, WLN: L C6666 1A Q IVJ, AKOS002319374, MCULE-6216392978, NSC-631641, NCGC00095343-01, NCGC00095343-02, NCGC00178030-01, KB-74157, LS-27945, SMR001306791, ST028631, AB1003202, TR-025695, B0019, FT-0621414, A840240, S14-0791, BRD-K76872913-001-02-8, F0001-2103, A0950/0044472, 116495-96-6, 358773-23-6, 57608-35-2, tetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2(7),3,5,9,11,13(17),14-octaen-8-one

ID: 890

InChIKey: HULMNSIAKWANQO-JQKSAQOKSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2CC[C@@]3([C@H]4CC[C@@]5([C@H](CC[C@@]5([C@@H]4CC[C@@]3(C2)O)O)C6=CC(=O)OC6)C)C=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441852
synonyms found at PubChem are:
Convallatoxin, Convallotoxin, Corglycone, 508-75-8, Convallaotoxin, UNII-JY264VIR1Y, Convallaton, Corglycon, Korglykon, Strophanthidin 3-O-alpha-L-rhamnoside, Convallatoxoside, Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside), JY264VIR1Y, Corglykon, CHEBI:27663, 3beta-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide, 3beta-(6-deoxy-alpha-L-mannopyranosyloxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide, HSDB 3475, Strophanthidin alpha-L-rhamnoside, EINECS 208-086-3, NSC 407808, Rhamnoside, strophanthidin-3, alpha-L-, Mannopyranoside, strophanthidin-3,6-deoxy-, alpha-L-, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-, AC1L9BRW, Convallatoxin, >=65%, D0M2QH, SCHEMBL308440, CHEMBL399336, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)-3-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)hexadecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, ZINC8214530, LMST01120013, penta[a]phenanthrene-10-carbaldehyde, CC-25965, C08858, C-23195, 3beta-(alpha-L-rhamnopyranosyloxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide, 5beta,14beta-Dihydroxy-19-oxo-3beta[(alpha-L-rhamnopyranosyl)oxy]card-20,22-enolide, Card-20(22)-enolide, 3-[(6-deoxyhexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3beta,5beta)-3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-card-20(22)-enolide, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclo, (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)- (9CI)

ID: 891

InChIKey: HUOOMAOYXQFIDQ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5318569
synonyms found at PubChem are:
Isoginkgetin, 548-19-6, iso-ginkgetin, 4',4'''-Dimethylamentoflavone, CHEMBL1208903, CHEBI:79087, 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, Spectrum_000406, SpecPlus_000433, Spectrum2_000302, Spectrum3_001112, Spectrum4_001945, Spectrum5_000819, AC1NSX10, BSPBio_002844, KBioGR_002352, KBioSS_000886, DivK1c_006529, SPBio_000264, KBio1_001473, KBio2_000886, KBio2_003454, KBio2_006022, KBio3_002064, DTXSID00203271, HUOOMAOYXQFIDQ-UHFFFAOYSA-N, MolPort-003-665-806, BCP22629, HY-N2117, ZINC3197535, 3''',8-Biflavone, 5,5'',7,7''-tetrahydroxy-4',4'''-dimethoxy-, BDBM50323203, CCG-38579, AKOS032948383, CS-5763, SDCCGMLS-0066448.P001, NCGC00094722-01, NCGC00094722-02, NCGC00178438-01, 4CN-1291, SC-20446, FT-0706639, Y0114, BRD-K72661036-001-02-1, 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-methoxy-5-(4-oxo-5,7-dihydroxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-, 4H-1-Benzopyran-4-one,8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-, 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one

ID: 892

InChIKey: HUPFGZXOMWLGNK-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2=C(C=C(C=C2)F)F)C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3059
synonyms found at PubChem are:
diflunisal, 22494-42-4, Dolobid, Fluniget, Dolobis, Flovacil, Fluodonil, Adomal, Flustar, Diflunisalum, Difludol, Algobid, Citidol, Noaldol, Reuflos, Unisal, 5-(2,4-Difluorophenyl)salicylic acid, Diflusinal, Dolisal, Dolobil, 5-(2,4-difluorophenyl)-2-hydroxybenzoic acid, MK 647, MK-647, Diflunisalum [INN-Latin], 5-[2,4-Difluorophenyl]salicylic acid, 2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid, [1,1'-Biphenyl]-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-, 2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid, UNII-7C546U4DEN, Dolobid (TN), C13H8F2O3, 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Diflunisal [USAN:INN:BAN:JAN], EINECS 245-034-9, 2',4'-Difluoro-4-hydroxy-(1,1'-biphenyl)-3-carboxylic acid, CHEMBL898, 2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid, BRN 2654431, Diflunisal (JAN/USP/INN), MLS000028678, 7C546U4DEN, 3-BIPHENYLCARBOXYLIC ACID, 2',4'-DIFLUORO-4-HYDROXY-, CHEBI:39669, (1,1'-Biphenyl)-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-, HUPFGZXOMWLGNK-UHFFFAOYSA-N, Diflunisal-d3, NCGC00016765-01, SMR000058723, CAS-22494-42-4, DSSTox_CID_2932, DSSTox_RID_76792, DSSTox_GSID_22932, 2',4'-difluoro-4-hydroxy-biphenyl-3-carboxylic acid, 2',4'-Difluoro-4-hydroxy[1,1'-biphenyl]-3-carboxylic acid, Dolocid, Apo-Diflunisal, Novo-Diflunisal, Nu-Diflunisal, 1FL, SR-01000003165, 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid, MK647, Prestwick_168, Diflunisal [USAN:USP:INN:BAN:JAN], PubChem14748, Spectrum_000962, Opera_ID_803, Prestwick0_000039, Prestwick1_000039, Prestwick2_000039, Prestwick3_000039, Spectrum2_001012, Spectrum3_000392, Spectrum4_000513, Spectrum5_000901, Merck Brand of Diflunisal, Diflunisal Novopharm Brand, difluorophenylsalicylic acid, Apotex Brand of Diflunisal, D08LFZ, AC1L1F2Z, SCHEMBL4337, BSPBio_000137, BSPBio_002203, KBioGR_001085, KBioSS_001442, MLS001146895, Novopharm Brand of Diflunisal, Nu Pharm Brand of Diflunisal, Nu-Pharm Brand of Diflunisal, BIDD:GT0063, DivK1c_000938, SPECTRUM1500245, Frosst SA Brand of Diflunisal, SPBio_001163, SPBio_002058, Diflunisal, analytical standard, BPBio1_000151, GTPL7162, DTXSID5022932, CTK1A3255, HMS502O20, KBio1_000938, KBio2_001442, KBio2_004010, KBio2_006578, KBio3_001423, ZINC20243, MolPort-001-727-460, NINDS_000938, HMS1568G19, HMS1920G10, HMS2090C16, HMS2091M20, HMS2095G19, HMS3259G17, HMS3712G19, Pharmakon1600-01500245, BCP09905, KS-00000KD6, ZX-AH027458, ZX-AP008530, Tox21_110598, BDBM50240510, CCG-40230, MFCD00057834, NSC756728, s4609, SBB058143, AKOS005762917, Tox21_110598_1, API0002353, Cahill May Roberts Brand of Diflunisal, DB00861, KS-1346, MCULE-8281018918, NC00506, NSC-756728, PC11123, TRA0051767, IDI1_000938, SEL14865206, Merck Sharp & Dohme Brand of Diflunisal, NCGC00016765-02, NCGC00016765-03, NCGC00016765-04, NCGC00016765-05, NCGC00016765-06, NCGC00016765-09, NCGC00022783-03, NCGC00022783-04, AJ-08419, AK161747, AN-17922, CC-26785, CPD000058723, H776, HY-18342, KB-83891, LS-44258, SAM002554896, SC-13811, SBI-0051347.P003, AB0013252, AX8003209, KB-195553, AB00051969, CS-0007468, FT-0630487, ST24046572, ST51014978, C01691, D00130, J10103, AB00051969-12, AB00051969_13, A816230, C-15398, 2',4'-difluoro-4-hydroxybipheny-3-carboxylic acid, I01-3451, J-014739, SR-01000003165-2, SR-01000003165-3, 5-[2,4-bis(fluoranyl)phenyl]-2-oxidanyl-benzoic acid, BRD-K22031190-001-05-3, BRD-K22031190-001-13-7, Diflunisal, European Pharmacopoeia (EP) Reference Standard, [1,1'-Biphenyl]-3-carboxylicacid, 2',4'-difluoro-4-hydroxy-, 2',4'-Difluoro-4-hydroxy-(1',1-diphenyl)-3-carboxylic acid, Diflunisal, United States Pharmacopeia (USP) Reference Standard, 1286107-99-0

ID: 893

InChIKey: HUXJGSHUVDWZAM-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(C(=C(C=C1C)O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3940691
synonyms found at PubChem are:
Ethyl hematommate, HAEMATOMMIC ACID, ETHYL ESTER, ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate, 39503-14-5, Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, ethyl ester, Ethyl haematommate, SpecPlus_000064, AC1N0NMT, Spectrum2_000629, Spectrum3_000886, Spectrum4_000978, Spectrum5_001812, Hematommic acid ethyl ester, Haematommic acid ethyl ester, KBioGR_001355, SPECTRUM205071, DivK1c_006160, SPBio_000598, BEN495, CHEMBL493032, SCHEMBL12998324, CTK1B3898, KBio1_001104, KBio3_001772, DTXSID60398112, HUXJGSHUVDWZAM-UHFFFAOYSA-N, ZINC3200778, CCG-38544, AKOS022655023, SDCCGMLS-0066940.P001, NCGC00095517-01, Ethyl 3-formyl-6-methyl-2,4-dihydroxy-benzoate, SR-05000002469, SR-05000002469-1

ID: 894

InChIKey: HVJCRMIQAMEJNM-UHFFFAOYSA-N
SMILES: CC1CCN=C(S1)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2733501
synonyms found at PubChem are:
AMT hydrochloride, 21463-31-0, 1121-91-1, 2-amino-5,6-dihydro-6-methyl-4h-1,3-thiazine, (+/-)-AMT hydrochloride, 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride, 6-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride, SR-01000075481, (y)-AMT hydrochloride, (?)-AMT hydrochloride, AC1MBZ1R, EU-0100085, C5H10N2S.HCl, MLS000862202, SCHEMBL431260, CHEMBL1255839, CTK8F7761, DTXSID60369928, MolPort-003-940-369, Tox21_500085, 1614AH, MFCD00717539, AKOS015903118, AMT drug for sale at a moderate price, CCG-221389, LP00085, NCGC00093589-01, NCGC00260770-01, SMR000326965, ( inverted question mark)-AMT hydrochloride, ST50824905, A 9834, J-014084, SR-01000075481-1, SR-01000075481-3, I14-18559, I14-41252, 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine, >=98%, 6-methyl-4,5-dihydro-6H-1,3-thiazine-2-ylamine, chloride, 6-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine,hydrochloride, ( inverted question mark)-2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride

ID: 895

InChIKey: HVYWMOMLDIMFJA-DPAQBDIFSA-N
SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5997
synonyms found at PubChem are:
cholesterol, 57-88-5, Cholesterin, Cholesteryl alcohol, Cholest-5-en-3beta-ol, Cholestrin, Cordulan, Dusoline, Dusoran, Cholesterine, Cholestrol, Hydrocerin, Dythol, Kathro, Lanol, Super hartolan, Provitamin D, Cholesterol base H, Lidinite, Lidinit, Nimco cholesterol base H, Wool alcohols B. P., (-)-Cholesterol, Tegolan (VAN), 5:6-Cholesten-3beta-ol, Cholest-5-en-3-beta-ol, Tegolan, 3beta-Hydroxycholest-5-ene, (3beta)-cholest-5-en-3-ol, Cholest-5-en-3-ol (3beta)-, 3-beta-Hydroxycholest-5-ene, 5-Cholesten-3beta-ol, CCRIS 2834, Dastar, Cholest-5-en-3-ol, HSDB 7106, delta(sup 5)-Cholesten-3-beta-ol, Fancol CH, 3beta-Hydroxy-5-cholestene, NSC 8798, UNII-97C5T2UQ7J, Epicholesterol, 5-Cholesten-3B-ol, CHEBI:16113, AI3-03112, Nimco cholesterol base No. 712, Cholest-5-en-3-ol, (3beta)-, 5:6-Cholesten-3-ol, EINECS 200-353-2, 5-Cholesten-3.beta.-ol, Cholest-5-en-3.beta.-ol, 5,6-Cholesten-3.beta.-ol, 3.beta.-Hydroxycholest-5-ene, 97C5T2UQ7J, NSC8798, HVYWMOMLDIMFJA-DPAQBDIFSA-N, (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, NCGC00159351-02, Cholest-5-en-3-ol (3.beta.)-, (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol, 80356-14-5, Cholesterinum, Cholesterol-t, 3h-cholesterol, (3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, CLR, (3H)-Cholesterol, Cholesterol [USAN:JAN], epicholesterin, Cholesteril, Cholesterol [BAN:JAN:NF], .DELTA.5-Cholesten-3-.beta.-ol, 1zhy, Cholesterol,(S), Cholest-5-en-3-ol, (3.beta.)- #, Cholesterol (TN), sterol;Cholesterin,Cholest-5-en-3beta-ol, 20-epi-cholesterol, 20-iso-cholesterol, Cholesterol, 94%, Wool alcohols B. P, Liquid crystal CN/9, (+)-ent-Cholesterol, cholest-5-en-3b-ol, 5-cholestene-3beta-ol, PubChem19974, 5-Cholesten-3bet.-ol, Cholesterol, 99.0%, AC1L1LKO, AC1Q1PAZ, Cholesterol (JP17/NF), DSSTox_CID_2401, Phospholipon & Cholesterol, 3ss-Cholest-5-en-3-ol, D02DLW, Delta5-Cholesten-3beta-ol, Epitope ID:150761, EC 200-353-2, 3beta-cholest-5-en-3-ol, Cholesterol, 95% 50g, 3bet.-Hydroxy-5-cholestene, DSSTox_RID_76573, BIDD:PXR0095, DSSTox_GSID_22401, (3b)-cholest-5-en-3-ol, 5:6-Cholesten-3.beta.-ol, KSC497S9L, 20bFH-cholest-5-en-3b-ol, BIDD:ER0548, Cholest-5-en-3-ol (3beta)-, labeled with tritium, CHEMBL112570, GTPL2718, DTXSID3022401, BDBM20192, CTK3J7995, (20bFH)-cholest-5-en-3b-ol, BBC/344, MolPort-002-506-911, (10R,13R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol, 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, Cholesterol, Sigma Grade, >=99%, HY-N0322, NSC-8798, ZINC3875383, Tox21_111595, ANW-32821, CMC_13392, LMST01010001, MFCD00003646, s4154, SBB058670, AKOS005267135, Cholest-5-en-3-ol, (3-.beta.)-, CS-5106, DB04540, GS-6857, MCULE-6413140986, RTR-020177, CAS-57-88-5, Cholesterol, NIST(R) SRM(R) 911c, SMP1_000069, NCGC00159351-03, 22243-67-0, AN-23591, Cholesterol, tested according to Ph.Eur., CJ-11010, KB-48897, LS-53159, SC-18458, TL8003721, TR-020177, Cholesterol, from lanolin, >=95.0% (GC), Cholesterol, from lanolin, >=99.0% (GC), ST24045331, (3beta,14beta,17alpha)-cholest-5-en-3-ol, 1889-EP2269610A2, 1889-EP2269977A2, 1889-EP2269989A1, 1889-EP2269990A1, 1889-EP2270011A1, 1889-EP2270505A1, 1889-EP2272822A1, 1889-EP2272825A2, 1889-EP2272834A1, 1889-EP2272841A1, 1889-EP2272843A1, 1889-EP2274983A1, 1889-EP2275105A1, 1889-EP2277507A1, 1889-EP2277565A2, 1889-EP2277566A2, 1889-EP2277567A1, 1889-EP2277568A2, 1889-EP2277569A2, 1889-EP2277570A2, 1889-EP2277865A1, 1889-EP2280001A1, 1889-EP2280282A1, 1889-EP2281817A1, 1889-EP2281824A1, 1889-EP2281899A2, 1889-EP2284157A1, 1889-EP2284158A1, 1889-EP2286795A1, 1889-EP2287165A2, 1889-EP2287166A2, 1889-EP2289510A1, 1889-EP2289883A1, 1889-EP2292228A1, 1889-EP2292234A1, 1889-EP2292280A1, 1889-EP2292596A2, 1889-EP2292612A2, 1889-EP2292620A2, 1889-EP2295406A1, 1889-EP2295409A1, 1889-EP2295411A1, 1889-EP2295417A1, 1889-EP2295429A1, 1889-EP2295439A1, 1889-EP2298312A1, 1889-EP2298728A1, 1889-EP2298731A1, 1889-EP2298735A1, 1889-EP2298742A1, 1889-EP2298745A1, 1889-EP2298747A1, 1889-EP2298772A1, 1889-EP2298776A1, 1889-EP2298779A1, 1889-EP2301923A1, 1889-EP2301929A1, 1889-EP2301935A1, 1889-EP2301936A1, 1889-EP2305648A1, 1889-EP2305668A1, 1889-EP2305674A1, 1889-EP2305695A2, 1889-EP2305696A2, 1889-EP2305697A2, 1889-EP2305698A2, 1889-EP2305825A1, 1889-EP2308479A2, 1889-EP2308838A1, 1889-EP2308839A1, 1889-EP2308858A1, 1889-EP2309584A1, 1889-EP2311811A1, 1889-EP2311816A1, 1889-EP2311817A1, 1889-EP2311821A1, 1889-EP2311823A1, 1889-EP2311825A1, 1889-EP2311836A1, 1889-EP2311841A1, 1889-EP2314295A1, 1889-EP2314576A1, 1889-EP2314588A1, 1889-EP2314593A1, 1889-EP2316457A1, 1889-EP2316458A1, 1889-EP2316470A2, 1889-EP2316825A1, 1889-EP2316826A1, 1889-EP2316827A1, 1889-EP2316828A1, 1889-EP2377510A1, C00187, D00040, Z-0798, AB00443913_03, Cholesterol, >=95% (GC), powder, Ash, free, Cholesterol, Vetec(TM) reagent grade, >=92.5%, Soya phospholipon & Cholesterol (2:1 molar ratio), W-105431, 5BBA213B-ECF4-44AF-8AAF-8A0120F2F886, Cholesterol (cGMP, animal-origin free, vegetal-derived), Cholesterol, from sheep wool, >=92.5% (GC), powder, WLN: L E5 B666 LUTJ A1 E1 FY1&3Y1&1 OQ, Cholesterol (non-cGMP, animal-origin free, vegetal-derived), Cholesterol, European Pharmacopoeia (EP) Reference Standard, Cholesterol, powder, BioReagent, suitable for cell culture, >=99%, Cholesterol, United States Pharmacopeia (USP) Reference Standard, Cholesterol solution, certified reference material, 10 mg/mL in chloroform, Cholesterol, Pharmaceutical Secondary Standard; Certified Reference Material, PhytoChol® Puriss (animal-origin free, vegetal-derived Cholesterol), Cholesterol, from sheep wool, Controlled origin, meets USP/NF testing specifications, (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-7-en-5-ol, 129111-15-5, 14-((1R)-1,5-dimethylhexyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyltetracyclo[ 8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol, 209124-38-9, 218965-24-3, 262418-13-3, 378185-03-6, 676322-57-9, 71539-33-8, 732297-95-9, 793670-51-6, 80356-33-8, 849593-11-9, 856708-55-9, Cholesterol, Plant-Derived, SyntheChol(R), PharmaGrade, USP/NF, Ph Eur, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, SyntheChol(R) NS0 Supplement, 500 x, synthetic cholesterol, animal component-free, aqueous solution, sterile-filtered, suitable for cell culture

ID: 896

InChIKey: HWGBHCRJGXAGEU-UHFFFAOYSA-N
SMILES: CC1=CC(=O)NC(=S)N1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4161
synonyms found at PubChem are:
methylthiouracil, 6-Methyl-2-thiouracil, 56-04-2, Methiocil, 4-hydroxy-2-mercapto-6-methylpyrimidine, Thimecil, Thiomecil, Thiothymin, Alkiron, Metacil, 2-Mercapto-6-methylpyrimidin-4-ol, 2-Thio-6-methyluracil, Basethyrin, Prostrumyl, Thyreonorm, Thyreostat, Tiomeracil, Antibason, Basecil, Methacil, Methiacil, Methicil, Muracil, Orcanon, Strumacil, Thiomidil, Thioryl, Thiuryl, Tiotiron, Thyril, Thyreostat I, Tiorale M, 6-Methylthiouracil, 4-Methyl-2-thiouracil, 6-Thio-4-methyluracil, Usaf ek-6454, 6-Methyl-2-mercaptouracil, Uracil, 6-methyl-2-thio-, 6-methyl-2-sulfanylpyrimidin-4-ol, 6-Methyl-2-thiouracyl, Methyl thiouracil, 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-, Rcra waste number U164, 6-Metil-tiouracile, Methacil (VAN), Alkiron (VAN), Metacil (VAN), 2-Mercapto-4-hydroxy-6-methylpyrimidine, 2-Mercapto-6-methylpyrimid-4-one, 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, Thiothyron, Muracin, Metiltiouracile [DCIT], 2-Thio-6-methyl-1,3-pyrimidin-4-one, 2-Thio-4-oxo-6-methyl-1,3-pyrimidine, 2-Mercapto-6-methyl-4-pyrimidinol, C5H6N2OS, CCRIS 409, 6-Metil-tiouracile [Italian], NSC 193526, UNII-QW24888U5F, Metiltiouracilo [INN-Spanish], Methylthiouracile [INN-French], Methylthiouracilum [INN-Latin], 2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone, 6-Methyl-2-thiouracyl [Czech], HSDB 3366, Methylthiouracil [INN], 2-Mercapto-6-methyl-4-pyrimidone, EINECS 200-252-3, 4-Hydroxy-6-methyl-2-thiopyrimidine, RCRA waste no. U164, AI3-25476, MLS000069452, MTU, 6-methyl-2-sulfanylidene-1H-pyrimidin-4-one, CHEBI:82346, 6-Methyl-2-thio-2,4-(1H3H)-pyrimidinedione, HWGBHCRJGXAGEU-UHFFFAOYSA-N, 6-Methyl-2-thio-2,4-(1H,3H)-pyrimidinedione, QW24888U5F, 6-Methyl-4-oxo-2-thioxo1,2,3,4-tetrahydropyrimidine, NCGC00091124-02, 6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one, Methylthiouracil (INN), SMR000059030, DSSTox_CID_890, DSSTox_RID_75847, DSSTox_GSID_20890, WLN: T6MYMVJ BUS F1, 6-Methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one, Metiltiouracile, Metiltiouracilo, Methylthiouracile, Methylthiouracilum, CAS-56-04-2, 6-Methyl-2-thio-2,3H)-pyrimidinedione, 91795-77-6, Methylthiouracil [USP:INN], Thioyl, prostru myl, Thimecil (TN), Prestwick_330, Methyl-6-thiouracil, ACMC-20dlnj, Spectrum_001031, 6-Hydroxy-2-mercapto-4-methylpyrimidine;, Opera_ID_172, Spectrum2_001276, Spectrum3_000676, Spectrum4_000864, Spectrum5_001325, 2-Thiouracil, 6-methyl-, AC1LDI79, BSPBio_002371, KBioGR_001527, KBioSS_001511, KSC714C2T, MLS002415706, MLS004491793, DivK1c_000719, SCHEMBL159989, SPECTRUM1500408, SPBio_001272, ACMC-20976a, CHEMBL1330588, DTXSID2020890, SCHEMBL11433163, URACIL,6-METHYL,2-THIO, CTK3J0890, CTK6B4129, HMS502D21, KBio1_000719, KBio2_001511, KBio2_004079, KBio2_006647, KBio3_001591, NSC9378, MolPort-000-873-077, MolPort-000-917-207, MolPort-001-765-909, MolPort-002-358-059, NINDS_000719, 2-thio-6-methyl-pyrimidin-4-one, HMS1757B09, HMS1923M13, HMS2091F08, HMS2231B20, HMS3370O12, HMS3652O03, KUC108906N, Pharmakon1600-01500408, 2-thio-6-methyl-pyrimidin-4 -one, BCP21374, HY-B0513, KS-000001WN, NSC 9378, NSC-9378, STR00648, ZINC5037820, Tox21_111088, Tox21_201870, Tox21_300497, 2-mercapto-6-methyl-pyrimidin-4-ol, ANW-13568, BBL013188, CCG-39119, NSC193526, NSC757116, s3138, SBB004144, STL163967, STL352586, STL352692, 6-Methyl-2-thiouracil, 98% 50g, AKOS000119183, AKOS001015710, AKOS001777669, AKOS002663079, AKOS025117304, Tox21_111088_1, 4-hydroxy-6-methyl-pyrimidine-2-thiol, AM87068, CCG-214821, CS-2723, KSC-27-038, LS-1371, LS20666, MCULE-5250952546, NSC-193526, NSC-757116, PS-4510, RP20750, RTR-037091, TRA0025589, 6-methyl-2-thioxo-1H-pyrimidin-4-one, IDI1_000719, NCGC00091124-01, NCGC00091124-03, NCGC00091124-04, NCGC00091124-05, NCGC00091124-06, NCGC00093364-02, NCGC00178683-01, NCGC00254505-01, NCGC00259419-01, 6-methyl-2-sulfanylpyrimidin-4(3H)-one, AC-10803, AJ-53005, BR-26985, CJ-12409, HC210062, KB-68908, SC-26753, SBI-0051446.P003, 4-hydroxy-6-methylpyrimidine-2(1h)-thione, AB1000515, ST2412446, TL8004448, TR-037091, EU-0095998, FT-0621218, M0443, ST50308195, X4760, 4-Hydroxy-2-mercapto-6-methylpyrimidine, 95%, 6-Methyl-2-thio-2,4(1H,3H)-pyrimidinedione, C19265, D07231, S-1424, 044M552, 795M776, A830898, AC-907/30003038, SR-05000002026, 2,3-dihydro-6-methyl-2-thioxopyrimidin-4(1H)-one, 4[1H]-Pyrimidinone, 2,3-dihydro-6-methyl-thioxo, 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone, I03-0100, SR-05000002026-1, W-105535, 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone #, 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine, F0213-0019, F0827-0300, 6-Methyl-2-thiouracil, VETRANAL(TM), analytical standard, 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo- (9CI), 6-Methyl-2-thiouracil, purum, >=98.0% S basis (elemental analysis), InChI=1/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9, 1123-10-0, 31909-18-9, MZU

ID: 897

InChIKey: HXCNRYXBZNHDNE-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N2C=CC=CC2=N1)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4847
synonyms found at PubChem are:
Pirenperone, 75444-65-4, Pirenperonum [INN-Latin], R-47,465, Pirenperona [INN-Spanish], UNII-Y9FMC4513X, EINECS 278-213-5, CHEMBL18331, MLS000069365, Y9FMC4513X, R-47465, NCGC00015784-07, SMR000058507, 3-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one, 4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl-, DSSTox_CID_25182, DSSTox_RID_80730, DSSTox_GSID_45182, C23H24FN3O2, Pirenperona, Pirenperonum, 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido-[1,2-a] pyrimidin-4-one, 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[2,1-b]pyrimidin-4-one, 3-[2-[4-(p-fluorobenzoyl)piperidino]ethyl]-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one, CAS-75444-65-4, SR-01000002998, Pirenperone [USAN:BAN:INN], Pirenperone [USAN:INN:BAN], 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methylpyrido[1,2-a]pyrimidin-4-one, Prestwick_858, Spectrum_001584, SpecPlus_000663, Lopac-P-126, AC1Q4NIA, Opera_ID_1876, Prestwick0_000531, Prestwick1_000531, Prestwick2_000531, Prestwick3_000531, Spectrum2_001680, Spectrum3_001655, Spectrum4_000620, Spectrum5_001827, Pirenperone (USAN/INN), D00PEU, AC1Q2F2M, Pirenperone, >97%, solid, Lopac0_001007, R 47456, R 50656, R-47456, R-50656, BSPBio_000541, BSPBio_003409, GTPL283, KBioGR_001180, KBioSS_002064, MLS001148188, MLS001424212, DivK1c_006759, SCHEMBL467209, SPECTRUM1504188, SPBio_001899, SPBio_002462, AC1L1J38, BPBio1_000597, DTXSID9045182, CHEBI:92444, CTK5E1570, KBio1_001703, KBio2_002064, KBio2_004632, KBio2_007200, KBio3_002629, HXCNRYXBZNHDNE-UHFFFAOYSA-N, MolPort-003-666-539, HMS1569L03, HMS1922F15, HMS2051H22, HMS2093C08, HMS2096L03, HMS2234F07, HMS3263I15, HMS3370M02, HMS3393H22, HMS3713L03, Pharmakon1600-01504188, ZINC538194, Tox21_110220, Tox21_501007, BDBM50024205, CCG-39087, MFCD00069332, NSC760095, AKOS030530791, Tox21_110220_1, LP01007, NC00316, NSC-760095, 3-(2-(4-(4-fluorobenzoyl)piperidino)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one, NCGC00015784-01, NCGC00015784-02, NCGC00015784-03, NCGC00015784-04, NCGC00015784-05, NCGC00015784-06, NCGC00015784-08, NCGC00015784-09, NCGC00015784-10, NCGC00015784-11, NCGC00015784-12, NCGC00015784-14, NCGC00021326-03, NCGC00021326-04, NCGC00021326-05, NCGC00021326-06, NCGC00178084-01, NCGC00178084-02, NCGC00261692-01, CPD000058507, SAM001246893, SBI-0050980.P003, LS-177186, CAS- 75444-65-4, EU-0101007, FT-0732988, P-126, VU0239628-6, D05495, AB00053292_16, C-52961, L000956, SR-01000002998-2, SR-01000002998-5, SR-01000002998-7, BRD-K25224017-001-05-2, BRD-K25224017-001-15-1, 3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]-ethyl-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one, 4H-Pyrido[1,2-a]pyrimidin-4-one,3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-, 3-[2-[4-(4-Fluorobenzoyl)-1- piperidinyl]-ethyl-2-methyl-4H- pyrido[1,2-a]pyrimidin-4-one, 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one(Pirenperone)

ID: 898

InChIKey: HXHWSAZORRCQMX-UHFFFAOYSA-N
SMILES: CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2082
synonyms found at PubChem are:
albendazole, 54965-21-8, Albenza, Eskazole, Valbazen, Zentel, Proftril, Albendazol, Albendazolum, Bilutac, Zental, SK&F 62979, SKF 62979, Metiazol, Methyl 5-(propylthio)-2-benzimidazolecarbamate, SK&F-62979, Albendazol [INN-Spanish], Albendazolum [INN-Latin], 5-(Propylthio)-2-carbomethoxyaminobenzimidazole, Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate, (5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester, methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate, O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate, SKF-62979, Albenza (TN), NSC 220008, UNII-F4216019LN, HSDB 7444, Albendazole [USAN:INN:BAN:JAN], EINECS 259-414-7, Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester, CHEMBL1483, Albendazole (JAN/USP/INN), CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER, methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate, ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle, CHEBI:16664, HXHWSAZORRCQMX-UHFFFAOYSA-N, Methyl-5-[propylthio]-2-benzimidazole carbamate, ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French], F4216019LN, methyl 5-(propylthio)-1H-benzo[d]imidazol-2-ylcarbamate, methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate, methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate, NCGC00016876-01, [5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester, CPD000036735, (5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester, CAS-54965-21-8, DSSTox_CID_2563, Methyl 5-(propyl-thio)-2-benzimidazolecarbamate, DSSTox_RID_76632, DSSTox_GSID_22563, methoxy-N-(5-propylthiobenzimidazol-2-yl)carboxamide, methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate, methyl N-(5-propylsulfanyl-1H-benzimidazol-2-yl)carbamate, Albendoral, Andazol, Bendapar, Digezanol, Disthelm, Endoplus, Gascop, Lurdex, [5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate, Mediamix V Disthelm, albamelin, Albendazole Monohydrochloride, albendol, Monohydrochloride, Albendazole, Zenteltrade mark, Andazol), Albenzatrade mark, Andazoltrade mark, Eskazoletrade mark, Albendazole,(S), Eskazole (TN), SKF62979, Prestwick_675, Albendazole(Albenza), SK&F62979, Zentel (TN), Disthelm, Mediamix V, V Disthelm, Mediamix, Albendazole (Albenza), Albendazole [USAN:USP:INN:BAN:JAN], Albendazole Diba Brand, Spectrum_001532, Albendazole Pfizer Brand, AC1L1CVL, AC1Q2YKD, Albendazole Fustery Brand, Albendazole Hormona Brand, Prestwick0_000247, Prestwick1_000247, Prestwick2_000247, Prestwick3_000247, Spectrum4_000201, Spectrum5_001567, ChemDivAM_000003, Diba Brand of Albendazole, Albendazole Liferpal Brand, ChemDiv1_000190, Albendazole Armstrong Brand, Albendazole Sanicoopa Brand, D00KVO, Pfizer Brand of Albendazole, Albendazole Valdecasas Brand, Albendazole, 98% 10g, Fustery Brand of Albendazole, Hormona Brand of Albendazole, Oprea1_429292, Oprea1_585016, Oprea1_640007, SCHEMBL44682, BSPBio_000034, BSPBio_002548, KBioGR_000801, KBioSS_002012, KSC492E0L, Liferpal Brand of Albendazole, MLS000069722, BIDD:GT0615, DivK1c_000704, SPECTRUM1503903, Armstrong Brand of Albendazole, Sanicoopa Brand of Albendazole, SPBio_002253, Albendazole Noe-Socopharm Brand, BPBio1_000038, Valdecasas Brand of Albendazole, DTXSID0022563, CTK3J2205, HMS502D06, HMS587I14, HXHWSAZORRCQMX-UHFFFAOYSA-, KBio1_000704, KBio2_002012, KBio2_004580, KBio2_007148, KS-00000KMZ, MolPort-000-726-929, MolPort-000-760-571, MolPort-001-932-918, NINDS_000704, HMS1568B16, HMS1922K04, HMS2090G19, HMS2093K13, HMS2095B16, HMS2231O03, HMS3259B05, HMS3369C03, HMS3651C15, HMS3712B16, Pharmakon1600-01503903, Noe Socopharm Brand of Albendazole, Noe-Socopharm Brand of Albendazole, BCP12108, HY-B0223, Tox21_110659, Tox21_302300, AC-015, ANW-42170, BBL005883, BDBM50241293, CCG-39620, MFCD00083232, N-[6-(propylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, NSC220008, NSC758644, s1640, SBB056658, STK387550, STL046130, ZINC17146904, AKOS000540882, AKOS005431684, AKOS005699352, Tox21_110659_1, CCG-220247, CS-2170, DB00518, KS-5159, MCULE-5872469561, NC00615, NE41026, NSC-220008, NSC-758644, RP29454, RTR-019407, IDI1_000704, SmithKline Beecham Brand of Albendazole, NCGC00016876-02, NCGC00016876-03, NCGC00016876-04, NCGC00016876-05, NCGC00016876-06, NCGC00016876-07, NCGC00016876-08, NCGC00016876-09, NCGC00016876-10, NCGC00016876-12, NCGC00022896-03, NCGC00022896-04, NCGC00022896-05, NCGC00022896-06, NCGC00022896-07, NCGC00022896-08, NCGC00255250-01, Albendazole, analytical standard, >=98%, AN-16210, BAS 00439961, BC202024, CJ-15743, LS-50618, SAM002548932, SAM002589939, SC-17581, SMR000036735, ST012016, SBI-0051849.P002, Smith Kline & French Brand of Albendazole, AB0012898, AB1009519, KB-334951, TL8003543, TR-019407, AB00052377, FT-0621945, methyl 5-propylthio-2-benzimidazolecarbamate, T9034, EN300-49850, methyl 5-propylthio-2-benzimidazole carbamate, VU0239747-6, BIM-0051849.0001, C01779, D00134, J10424, AB00052377-13, AB00052377-14, AB00052377_15, AB00052377_16, Albenza, Eskazole, Zentel, Andazol, Albendazole, A830429, Albendazole, Antibiotic for Culture Media Use Only, SR-01000000171, SR-05000001875, I01-0380, methyl 5-(propylthio)-1H-benzimidazol-2-ylcarbamate, Q-200603, Q-200604, SR-01000000171-2, SR-05000001875-1, BRD-K79131256-001-04-7, BRD-K79131256-001-08-8, methyl 6-(propylthio)-1H-benzo[d]imidazol-2-ylcarbamate, Z1245635850, 2-[(Methoxycarbonyl)amino]-5-propylthio-1H-benzimidazole, Albendazole, European Pharmacopoeia (EP) Reference Standard, Methyl (6-(propylthio)-1H-benzo[d]imidazol-2-yl)carbamate, Methyl 5-(propylsulfanyl)-1H-benzimidazol-2-ylcarbamate #, MethylN-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate, Albendazole, United States Pharmacopeia (USP) Reference Standard, Albendazole, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

ID: 899

InChIKey: HXTDAUGEZTYMGP-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=O)O2)C=C1N=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1871
synonyms found at PubChem are:
6-Nitroso-1,2-benzopyrone, 6-Nitrosocoumarin, 130506-22-8, 6-nitrosochromen-2-one, 2H-1-Benzopyran-2-one, 6-nitroso-, 2H-1-Benzopyran-2-one,6-nitroso-, 6-NO2BP, NOBP, ACMC-20dbyy, Lopac-N-8403, AC1L1CF3, AC1Q6R3N, Lopac0_000869, 6-nitroso-2H-chromen-2-one, SCHEMBL792923, CHEMBL1255659, CTK4B6758, DTXSID90156580, HMS3262N19, ZINC3871211, Tox21_500869, AKOS006271903, CCG-204951, LP00869, NCGC00015753-01, NCGC00015753-02, NCGC00015753-03, NCGC00015753-04, NCGC00094193-01, NCGC00094193-02, NCGC00261554-01, AJ-46342, RT-010698, EU-0100869, N 8403, SR-01000076033, J-005818, SR-01000076033-1, 6-Nitroso-1,2-benzopyrone, ADP-ribosyltransferase inhibitor

ID: 900

InChIKey: HXTFHSYLYXVTHC-AJHDJQPGSA-N
SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 442431
synonyms found at PubChem are:
Narirutin, 14259-46-2, Isonaringenin, Isonaringin, Naringenin 7-O-rutinoside, Naringenin-7-O-rutinoside, UNII-06M5EAT0YC, 06M5EAT0YC, CHEBI:28705, (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside, Q-100159, Naringenin 7-beta-rutinoside, FEMA No. 2769, (2S)-Narirutin, EINECS 238-138-0, NARINGEN, Naringin extract (Citrus paradisi Macf.), AC1L9CT8, SCHEMBL669946, CHEMBL446246, Narirutin, >=98% (HPLC), MolPort-006-120-936, KS-00000KC1, ZINC8234300, AKOS030530132, CC-32464, SC-82702, FT-0630414, N1696, X1191, C09793, 259N462, C-23278, Flavanone, 4',5,7-trihydroxy-, 7-beta-rutinoside, (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one, (S)-5-hydroxy-2-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)methyl)tetrahydro-2H-pyran-2-yloxy)chroman-4-one, (S)-7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 26264-36-8, 32737-62-5, 4493-40-7, 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoxyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (S)-, 4H-1-benzopyran-4-one, 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-, 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-,(2S)-

ID: 901

InChIKey: HXYVTAGFYLMHSO-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)NCCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4671
synonyms found at PubChem are:
Palmitoylethanolamide, Palmidrol, 544-31-0, N-(2-Hydroxyethyl)hexadecanamide, Palmitamide MEA, Hydroxyethylpalmitamide, N-palmitoylethanolamine, N-(2-Hydroxyethyl)palmitamide, Palmitoyl ethanolamide, Impulsin, Palmitic acid monoethanolamide, Loramine P 256, Palmitoyl-EA, Palmidrolum, palmitylethanolamide, HEXADECANAMIDE, N-(2-HYDROXYETHYL)-, Palmidrol [INN], Anandamide (16:0), Palmidrolum [INN-Latin], Palmitinsaeure-beta-hydroxyethylamid, UNII-6R8T1UDM3V, Monoethanolamine palmitic acid amide, NSC 23320, hexadecanoyl ethanolamide, N-palmitoyl ethanolamine, EINECS 208-867-9, N-hexadecanoyl-ethanolamine, 6R8T1UDM3V, C18H37NO2, CHEBI:71464, HXYVTAGFYLMHSO-UHFFFAOYSA-N, Palmidrol (INN), Hexadecanamide,N-(2-hydroxyethyl)-, AM 3112, NCGC00015793-03, DSSTox_CID_22254, DSSTox_RID_79975, DSSTox_GSID_42254, MimyX, CAS-544-31-0, SR-01000076055, N-(2-hydroxyethyl)palmitate, 2-Palmitoylaminoethanol, Palmdrol prodes (TN), Tocris-0879, palmitic monoethanolamide, AC1L1IOV, AC1Q5PML, N-hexadecanoylethanolamine, Lopac-P-0359, Guanfacine extended release, D07ILQ, D08HMQ, D0M1FB, Palmityoletanolamide (PEA), CBiol_002043, Lopac0_000905, BSPBio_001454, KBioGR_000174, KBioSS_000174, MLS002153421, SCHEMBL120518, BML2-B10, CHEMBL417675, GTPL3622, DTXSID4042254, Palmidrol|N-palmitoylethanolamine, SCHEMBL19511663, BDBM29083, CTK8E7798, KBio2_000174, KBio2_002742, KBio2_005310, KBio3_000347, KBio3_000348, MolPort-003-708-445, Bio1_000329, Bio1_000818, Bio1_001307, Bio2_000174, Bio2_000654, HMS1361I16, HMS1791I16, HMS1989I16, HMS2234L19, HMS3264C10, HMS3266N08, HMS3374K03, HMS3402I16, HMS3649L03, N-(2-hydroxyethyl) hexadecanamide, Pharmakon1600-01506156, BCP29005, CS-D1253, NSC23320, ZINC8035017, Tox21_110222, BN0405, LMFA08040013, MFCD00020562, NSC-23320, NSC760371, s4708, STL454872, AKOS002676363, Tox21_110222_1, CCG-204987, LP00905, NSC-760371, TRA0000334, IDI1_033924, NCGC00015793-01, NCGC00015793-02, NCGC00015793-04, NCGC00015793-05, NCGC00015793-06, NCGC00015793-07, NCGC00015793-08, NCGC00015793-09, NCGC00015793-10, NCGC00024840-01, NCGC00024840-02, NCGC00024840-05, NCGC00024840-06, NCGC00024840-07, NCGC00024840-08, NCGC00024840-09, AS-14094, HY-20685, SMR000058371, LS-175551, TX-017897, B6485, EU-0100905, V1640, C16512, D08328, J90064, P 0359, AB00918319_06, SR-01000076055-1, SR-01000076055-3, SR-01000076055-7, BRD-K68095457-001-04-4, Z2687203832, UNII-3VVG2UI23S component HXYVTAGFYLMHSO-UHFFFAOYSA-N, Amides, C16-18 and C18-branched, unsatd., N-(hydroxyethyl), UNII-C80684146D component HXYVTAGFYLMHSO-UHFFFAOYSA-N, 71060-58-7

ID: 902

InChIKey: HYHSBSXUHZOYLX-WDSKDSINSA-N
SMILES: C(CC(=O)N[C@@H](CSN=O)C(=O)NCC(=O)O)[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 104858
synonyms found at PubChem are:
S-nitrosoglutathione, gsno, SNOG, 57564-91-7, Nitrosoglutathione, Glutathione thionitrite, N-(N-L-gamma-Glutamyl-S-nitroso-L-cysteinyl)glycine, S-NITROSO-L-GLUTATHIONE, CCRIS 2095, UNII-78RRI89ZTO, BRN 3566211, 78RRI89ZTO, (S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-(nitrosothio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid, CHEBI:50091, Glycine, N-(N-L-gamma-glutamyl-S-nitroso-L-cysteinyl)-, (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(nitrososulfanyl)ethyl]carbamoyl}butanoic acid, C10H16N4O7S, GNSO, AC1L2XMN, S-Nitrosoglutathione (GSNO), MLS002153427, CHEMBL63507, SCHEMBL154575, S-Nitrosoglutathione, >=97%, CTK8G3128, RVC 588, HYHSBSXUHZOYLX-WDSKDSINSA-N, MolPort-003-983-807, HMS3649M18, ZINC3872731, 2041AH, MFCD00214341, AKOS024458577, LS-72674, SMR001230802, B6370, FT-0672958, L-|A-Glutamyl-S-nitroso-L-cysteinyl-glycine, ST24036003, L-gamma-glutamyl-S-nitroso-L-cysteinylglycine, SR-01000946622, J-200350, SR-01000946622-1, N-(N-L-gamma-glutamyl- S-Nitroso-L-cysteinyl)glycine, N-(N-L-gamma-glutamyl-S-Nitroso-L-cysteinyl) Glycine, Z2754492658, 2,2?-Biquinoline-4,4?-dicarboxylic acid dipotassium salt trihydrate, (2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-1-(nitrososulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid, (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-nitrososulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid, (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-(nitrosothio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid

ID: 903

InChIKey: HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4485
synonyms found at PubChem are:
nifedipine, 21829-25-4, Procardia, Adalat, Procardia XL, Adalat CC, Cordipin, Corinfar, Fenihidine, Citilat, Oxcord, Fenihidin, Adalate, Nifediac, Afeditab CR, Bay-a-1040, Coracten, Hexadilat, Introcar, Kordafen, Nifangin, Nifedical, Tibricol, Adapine, Anifed, Pidilat, Sepamit, Zenusin, dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Orix, Adalat LA, Chronadalate, Dignokonstant, Nifedipinum, Adapress, Afeditab, Aldipin, Alfadal, Angipec, Aprical, Bonacid, Calcibloc, Calcigard, Calcilat, Cardifen, Cardilat, Cardionorm, Cordafen, Cordaflex, Cordalat, Cordicant, Cordilan, Cordipine, Corotrend, Corynphar, Dilafed, Dipinkor, Duranifin, Ecodipi, Ecodipin, Fenamon, Fenigidin, Hadipin, Korinfar, Macorel, Megalat, Myogard, Nedipin, Nifecard, Nifecor, Nifedicor, Nifedin, Nifedipino, Nifedipres, Nifelan, Nifelat, Nificard, Alonix, Anpine, Camont, Fedcor, Glopir, Coral, Depin, Alat, Adalat Retard, Fedcor Retard, Adalat Crono, Chronadalate LP, Adalat Oros, Ecodipin E, Apo-Nifed, Nifedipine-GTIS, Nifensar XL, Adipine XL, Alonix S, Fenamon SR, 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, Adalat CR, Adalat FT, Adalat LP, Adalat PA, Adalat GITS, Adalat 5, Adalat 10, Adalat 20, BAY A 1040, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester, Adalat GITS 30, Niphedipine, Alpha-Nifedipine Retard, Emaberin, Infedipin, Nicardia, Nifdemin, Nifebene, Nifedepat, Nifedine, Nifelate, Nifidine, Nifipen, Dilcor, Nifar, Aprical long, N1fedilat, Slofedipine XL, Fortipine LA, Nifedical XL, Nifedipinum [INN-Latin], Nifedirex LP, Tensipine MR, Coracten XL, Nifelat Q, Adalate LP, Nifedipine Retard, Nifedipino [INN-Spanish], Adalat XL, Procardia (TN), Bay-1040, Adalat (TN), Nifedipine (Adalat), CCRIS 6074, CHEBI:7565, Afeditab CR (TN), C17H18N2O6, CHEMBL193, UNII-I9ZF7L6G2L, I9ZF7L6G2L, 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, MLS000028521, HYIMSNHJOBLJNT-UHFFFAOYSA-N, Nifedipine [USAN:BAN:INN:JAN], KB-1712P, EINECS 244-598-3, Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-3,5-pyridinedicarboxylate, Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate, BRN 0497773, NCGC00015748-11, SMR000058291, CAS-21829-25-4, 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine, DSSTox_CID_5715, Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate, N 7634, DSSTox_RID_77889, DSSTox_GSID_25715, Vascard, Nifedipine GTIS, 4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine, 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester, 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester [German], Dimethyl 4-(2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, SR-01000075332, Nifedipine Monohydrochloride, Bay1040, fedipin, nifedipin, Monohydrochloride, Nifedipine, BAYa1040, Aldipine, Adalat, Procardia, Nifedipine,(S), Nifedical (TN), BAY 1040, methyl 5-(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine- 3-carboxylate, Prestwick_357, Nifedipine Bayer Brand, Nifedipine Orion Brand, Nifedipine KRKA Brand, Nifedipine Pfizer Brand, Spectrum_000979, Tocris-1075, Opera_ID_1816, Prestwick0_000063, Prestwick1_000063, Prestwick2_000063, Prestwick3_000063, Spectrum2_001058, Spectrum3_000516, Spectrum4_000074, Spectrum5_001278, Lopac-N-7634, Bayer Brand of Nifedipine, KRKA Brand of Nifedipine, Nifedipine, 98% 5g, Orion Brand of Nifedipine, D04OSE, Pfizer Brand of Nifedipine, AC1L1I9V, cid_4485, SCHEMBL3968, BIDD:PXR0034, CBiol_001826, Lopac0_000819, Oprea1_788617, BSPBio_000245, BSPBio_001391, BSPBio_002071, KBioGR_000111, KBioGR_000627, KBioGR_002400, KBioSS_000111, KBioSS_001459, KBioSS_002405, KSC202E9N, MLS000758222, MLS001148146, MLS001401371, ARONIS24171, BIDD:GT0442, DivK1c_000313, SPECTRUM1500431, SPBio_001016, SPBio_002166, BPBio1_000271, GTPL2514, Nifedipine (JP15/USP/INN), Nifedipine (JP17/USP/INN), AWD Pharma Brand of Nifedipine, BAY-a 1040, DTXSID2025715, BAY A1040, BCBcMAP01_000046, CTK1A2296, HMS500P15, HSDB 7775, KBio1_000313, KBio2_000111, KBio2_001459, KBio2_002400, KBio2_002679, KBio2_004027, KBio2_004968, KBio2_005247, KBio2_006595, KBio2_007536, KBio3_000221, KBio3_000222, KBio3_001571, KBio3_002879, KS-00000WTS, SYN3028, Adcock Ingram Brand of Nifedipine, cMAP_000042, MolPort-000-787-707, NINDS_000313, Bio1_000112, Bio1_000601, Bio1_001090, Bio2_000111, Bio2_000591, HMS1361F13, HMS1568M07, HMS1791F13, HMS1920P19, HMS1989F13, HMS2051O03, HMS2089H11, HMS2091H20, HMS2095M07, HMS2233B22, HMS3262D19, HMS3267G06, HMS3393O03, HMS3651M19, HMS3712M07, Pharmakon1600-01500431, AC1Q4254, ACT02669, BCP21147, HY-B0284, KS-000046XF, Tox21_110212, Tox21_200304, Tox21_500819, ANW-42547, BBL023163, BDBM50000778, BDBM50101817, CCG-40115, MFCD00057326, NSC757242, s1808, SBB012573, STK735567, ZINC85205448, 60299-11-8 (mono-hydrochloride), AKOS002942507, Nifedipine, >=98% (HPLC), powder, Tox21_110212_1, AC-8061, AN-8351, CCG-100758, CS-2296, DB01115, KS-1456, LP00819, MCULE-7336870265, NC00008, Nifedipine [USAN:USP:INN:BAN:JAN], NSC-757242, RTC-063561, Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, IDI1_000313, IDI1_033861, NCGC00015748-01, NCGC00015748-02, NCGC00015748-03, NCGC00015748-04, NCGC00015748-05, NCGC00015748-06, NCGC00015748-07, NCGC00015748-08, NCGC00015748-09, NCGC00015748-10, NCGC00015748-12, NCGC00015748-13, NCGC00015748-14, NCGC00015748-15, NCGC00015748-17, NCGC00021710-02, NCGC00024983-01, NCGC00024983-02, NCGC00024983-03, NCGC00024983-04, NCGC00024983-05, NCGC00024983-06, NCGC00024983-07, NCGC00024983-08, NCGC00091707-01, NCGC00091707-02, NCGC00091707-03, NCGC00257858-01, NCGC00261504-01, CJ-22221, CPD000058291, CPD004727070, SAM001246963, SC-15173, ST066898, SBI-0050796.P004, AB0012099, AB1009450, AJ-126377, TC-063561, EU-0100819, FT-0630478, FT-0653833, N0528, ST24048791, 29N254, BIM-0050796.0001, C07266, D00437, K-6191, AB00052051-05, AB00052051_06, AB00052051_07, 5-22-04-00268 (Beilstein Handbook Reference), L001054, I06-0051, I06-1286, Q-201471, SR-01000075332-1, SR-01000075332-3, SR-01000075332-4, SR-01000075332-6, BRD-K96354014-001-01-3, BRD-K96354014-001-10-4, Z90350374, F2173-0802, Nifedipine, British Pharmacopoeia (BP) Reference Standard, Nifedipine, European Pharmacopoeia (EP) Reference Standard, Nifedipine, United States Pharmacopeia (USP) Reference Standard, 2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine, 4-(2'-nitrophenyl)-2,6 dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridine, 4-(2'-nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridine, Nifedipine, Pharmaceutical Secondary Standard; Certified Reference Material, 1,4-Dihydro-2,6-dimethyl-4-(2- nitrophenyl)-3,5-pyridine- dicarboxylic acid dimethyl ester, 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridine-dicarboxylic acid dimethyl ester, 2,6-dimethyl-4-(2nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-dimethyl ester, Dimethyl (4-(2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate), Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate #, 101539-70-2, 101554-38-5, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester (9CI), 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-, dimethyl ester (8CI)

ID: 904

InChIKey: HYWYRSMBCFDLJT-UHFFFAOYSA-N
SMILES: CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4495
synonyms found at PubChem are:
nimesulide, 51803-78-2, Mesulid, N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide, Flogovital, Sulidene, Nimed, R-805, 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, Nisulid, Nimesulidum [INN-Latin], Nimesulida [INN-Spanish], R 805, UNII-V4TKW1454M, 4-Nitro-2-phenoxy-methanesulfonanilide, 4'-Nitro-2'-phenoxymethanesulfonanilide, Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-, EINECS 257-431-4, 4'-Nitro-2'-phenoxymethansulfonanilid, BRN 2421175, CHEMBL56367, MLS000069680, V4TKW1454M, Methanesulfonanilide, 4'-nitro-2'-phenoxy-, CHEBI:44445, HYWYRSMBCFDLJT-UHFFFAOYSA-N, NCGC00015725-02, SMR000058484, CAS-51803-78-2, N-(4-nitro-2-phenoxy-phenyl)methanesulfonamide, N-[4-Nitro-2-phenoxyphenyl]-methanesulfonamide, DSSTox_CID_17250, DSSTox_RID_79316, DSSTox_GSID_37250, W-105866, C13H12N2O5S, Antifloxil, Nimesulida, Nimesulidum, Guaxan, NIM, Nimesulide [BAN:INN], Nimesulide [INN:BAN], SR-01000000218, mesulide, nimesulin, nimsulid, sulidan, sulide, Dulanermin, Aldoron, Nimedex, Orthobid, CCRIS 8225, Nise Gel, Nimesulide,(S), Prestwick_618, Spectrum_001577, Nimesulide (JAN/INN), AC1L1IAM, Opera_ID_1247, Prestwick0_000194, Prestwick1_000194, Prestwick2_000194, Prestwick3_000194, Spectrum2_001541, Spectrum3_001576, Spectrum4_000178, Spectrum5_000964, Lopac-N-1016, D03SJA, D0C0JT, Lopac0_000855, SCHEMBL24882, BSPBio_000147, BSPBio_001103, BSPBio_003112, KBioGR_000443, KBioGR_000695, KBioSS_000443, KBioSS_002057, MLS001148268, DivK1c_000693, SPECTRUM1503231, SPBio_001382, SPBio_002068, N-(4-nitro-2-phenoxyphenyl), BPBio1_000163, GTPL7401, NIM-03, DTXSID3037250, BCBcMAP01_000034, HMS502C15, KBio1_000693, KBio2_000443, KBio2_002057, KBio2_003011, KBio2_004625, KBio2_005579, KBio2_007193, KBio3_000825, KBio3_000826, KBio3_002612, MolPort-003-849-391, NINDS_000693, Bio2_000382, Bio2_000862, HMS1362G05, HMS1568H09, HMS1792G05, HMS1922K17, HMS1990G05, HMS2089B14, HMS2095H09, HMS2234K19, HMS3262L11, HMS3269G17, HMS3371J19, HMS3403G05, HMS3649A04, HMS3655D13, HMS3712H09, Pharmakon1600-01503231, BCP10076, HY-B0363, ZINC4617749, Tox21_110207, Tox21_301850, Tox21_500855, BDBM50056999, CCG-39319, CN0038, EI-287, MFCD00079470, NSC758412, s2040, STL018679, AKOS015897356, Tox21_110207_1, AC-4524, CS-2420, DB04743, KS-1277, LP00855, MCULE-4217888990, NSC-758412, IDI1_000693, IDI1_002137, NCGC00015725-01, NCGC00015725-03, NCGC00015725-04, NCGC00015725-05, NCGC00015725-06, NCGC00015725-07, NCGC00015725-08, NCGC00015725-09, NCGC00015725-10, NCGC00015725-11, NCGC00015725-12, NCGC00015725-13, NCGC00015725-15, NCGC00015725-16, NCGC00021842-03, NCGC00021842-04, NCGC00021842-05, NCGC00021842-06, NCGC00021842-07, NCGC00021842-08, NCGC00255661-01, NCGC00261540-01, AN-11869, BC204061, LS-90290, SC-17925, SBI-0050831.P003, AB2000444, AB00052332, EU-0100855, FT-0630650, N0984, ST51015069, (methylsulfonyl)(4-nitro-2-phenoxyphenyl)amine, D01049, N 1016, AB00052332-16, AB00052332_17, AB00052332_18, n-(4-nitro-2-phenoxy-phenyl)-methanesulfonamide, N-[4-nitro-2-(phenoxy)phenyl]methanesulfonamide, 803N782, A828786, SR-01000000218-2, SR-01000000218-6, SR-01000000218-7, BRD-K76775527-001-06-2, BRD-K76775527-001-18-7, SR-01000000218-11, Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)- (9CI), Nimesulide, European Pharmacopoeia (EP) Reference Standard, Nimesulide, Pharmaceutical Secondary Standard; Certified Reference Material, Nimesulide for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 905

InChIKey: HYXITZLLTYIPOF-UHFFFAOYSA-N
SMILES: CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 164676
synonyms found at PubChem are:
Tanshinone IIA, 568-72-9, Tanshinone II, Tanshinone B, Dan Shen Ketone, Tanshinon II, 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione, UNII-4GPC9FQG6L, 4GPC9FQG6L, NSC 686518, MLS001048863, HYXITZLLTYIPOF-UHFFFAOYSA-N, C19H18O3, NSC686519, SMR000387068, 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione, 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione, Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-, Q-100654, Phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-, SR-01000758926, HSDB 8104, Tanshinone A, tanshinone II A, Tanshinone 2-A, Tanshinone Iia ,(S), Acid Red 5 sodium salt, AC1Q6JLQ, 1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dion, AC1L4V8J, BSPBio_001597, BSPBio_002426, KBioGR_000317, KBioSS_000317, MLS006011834, SPECTRUM1505824, CHEMBL187266, cid_164676, SCHEMBL2026738, Tanshinone IIA (Tanshinone B), BDBM83922, CTK5A5836, KBio2_000317, KBio2_002885, KBio2_005453, KBio3_000633, KBio3_000634, BIB6295, DTXSID60205352, CHEBI:108595, MolPort-002-507-310, Bio2_000317, Bio2_000797, HMS1361P19, HMS1791P19, HMS1989P19, HMS2089H08, HMS2270D15, HMS3402P19, HMS3656C11, NP474, BCP28199, HY-N0135, Tanshinone IIA, analytical standard, ZINC1650576, BBL028449, CT0134, GP2434, MFCD00238692, s2365, STK801917, Tanshinone IIA, >=97% (HPLC), AKOS004120032, AC-1440, ACN-035345, API0010219, CCG-207955, CCG-208275, NSC-686519, RTR-031585, IDI1_034067, NCGC00095709-01, NCGC00095709-02, NCGC00095709-03, NCGC00095709-04, NCGC00095709-05, NCGC00095709-06, NCGC00095709-08, AN-14938, AS-16136, BC205184, NCI60_031209, S594, SC-17279, AB0018692, LS-175776, NCGC00095709-02!TANSHINONE IIA, Tanshinone B, Tanshinone II, 568-72-9, TL8003671, TR-031585, FT-0652880, N1846, W-2832, 568T729, SR-01000758926-2, SR-01000758926-4, SR-01000758926-5, BRD-K00141480-001-03-0, I14-22013, Phenanthro[1,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-, Tanshinone IIA, European Pharmacopoeia (EP) Reference Standard, Tanshinone IIA, United States Pharmacopeia (USP) Reference Standard, 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione #, 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-quinone, 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-dione, 6,7,8,9-Tetrahydro-1,6,6-trimethylphenanthro[1,2-b]furan-10,11-dione, 6,6,14-trimethyl-12-oxatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(10),2(7),8,11(15),13-pentaene-16,17-dione, 6,6,14-trimethyl-12-oxatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15),13-pentaene-16,17-dione

ID: 906

InChIKey: HYYBABOKPJLUIN-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4044
synonyms found at PubChem are:
mefenamic acid, 61-68-7, Ponstel, 2-[(2,3-dimethylphenyl)amino]benzoic acid, Ponstan, Mephenamic acid, Parkemed, Coslan, Mefacit, Ponalar, Methenamic acid, Mephenaminic acid, Bonabol, Lysalgo, Tanston, Vialidon, 2-((2,3-Dimethylphenyl)amino)benzoic acid, Bafameritin-M, Tamany Bonsan, Acide mefenamique, Mefenaminsaeure, Ponstan forte, Namphen, Pontal, Mefanamic acid, Bafhameritin-M, Mefenacid, Ponstil, Ponstyl, Acido mefenamico, CN-35355, Acidum mefenamicum, HL 1, Mefedolo, Mefenamate, Mycasaal, N-2,3-Xylylanthranilic acid, Rolan, INF 3355, INF-3355, N-(2,3-Xylyl)anthranilic acid, AGN-1255, CI-473, CL 473, 2-(2,3-Dimethylanilino)benzoic acid, N-(2,3-Xylyl)-2-aminobenzoic acid, N-(2,3-Dimethylphenyl)anthranilic acid, Ac. mefenamico, Mefenaminic Acid, Mefenaminsaeure [German], Ac. mefenamico [Italian], in-M, Acide mefenamique [French], Acide mefenamique [INN-French], Acido mefenamico [INN-Spanish], Acidum mefenamicum [INN-Latin], Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-, Anthranilic acid, N-2,3-xylyl-, CN 35355, NSC 94437, Ponstel (TN), 2-(2,3-dimethylphenylamino)benzoic acid, UNII-367589PJ2C, HSDB 3115, EINECS 200-513-1, Benzoic acid, 2-((2,3-dimethylphenyl)amino)-, 2-Diphenylaminecarboxylic acid, 2',3'-dimethyl-, CHEMBL686, Mefenamic acid [USAN:INN:BAN:JAN], BRN 2216243, MLS000069709, CHEBI:6717, 2-(2,3-Xylidino)benzoic Acid, HYYBABOKPJLUIN-UHFFFAOYSA-N, NSC94437, Anthranilic acid, N-(2,3-xylyl)-, CI 473, 367589PJ2C, CAS-61-68-7, NCGC00016278-07, CPD000058188, SMR000058188, Benzoic acid, 2-(2,3-dimethylphenyl)amino-, M1782, DSSTox_CID_3243, DSSTox_RID_76938, DSSTox_GSID_23243, F0850-6853, Mefenamicacid, ID8, SR-01000000216, Mefenaminsaure, Ponstel, Ponstan, Mephadolor (TN), Dyfenamic (TN), Mafepain (TN), Parkemed (TN), Potarlon (TN), Prestwick_506, Ponstal (TN), Ponstan (TN), Meftal (TN), Mefenamic Acid,(S), Spectrum_000174, Opera_ID_542, Mefenamic acid [USAN:USP:INN:BAN:JAN], AC1L1HAE, AC1Q2NNQ, Prestwick0_000054, Prestwick1_000054, Prestwick2_000054, Prestwick3_000054, Spectrum2_001941, Spectrum3_001082, Spectrum4_001235, Spectrum5_001341, Anthranilic acid,3-xylyl-, D05FTJ, cid_4044, SCHEMBL3544, Oprea1_193889, BSPBio_000207, BSPBio_002724, KBioGR_001730, KBioSS_000654, MLS001074162, DivK1c_000298, SPECTRUM1501103, SPBio_002001, SPBio_002128, BPBio1_000229, GTPL2593, SGCUT00005, WLN: QVR BMR B1 C1, DTXSID5023243, Godecke Brand of Mefenamic Acid, HMS500O20, KBio1_000298, KBio2_000654, KBio2_003222, KBio2_005790, KBio3_001944, KS-00000WDA, ZINC20241, BRD8217, MolPort-001-839-968, NINDS_000298, HMS1568K09, HMS1921D13, HMS2090B07, HMS2092B17, HMS2095K09, HMS2232P18, HMS3259M19, HMS3370K18, HMS3652A10, HMS3712K09, Pharmakon1600-01501103, Mefenamic acid (JP17/USP/INN), Mefenamic acid, analytical standard, ALBB-025759, BCP08499, BRD-8217, HY-B0574, to_000071, Tox21_110344, Tox21_301983, BBL003564, BDBM50134036, CCG-39434, MFCD00051721, NSC-94437, NSC757834, s4078, SBB056999, STK666691, AKOS001025551, AKOS002388313, Benzoic acid,3-dimethylphenyl)amino]-, Tox21_110344_1, CS-2681, DB00784, MCULE-1031776135, NC00517, NSC-757834, IDI1_000298, SMP2_000141, 2-(2,3-Dimethylanilino)benzoic acid #, NCGC00016278-01, NCGC00016278-02, NCGC00016278-03, NCGC00016278-04, NCGC00016278-05, NCGC00016278-06, NCGC00016278-10, NCGC00022393-03, NCGC00022393-04, NCGC00022393-05, NCGC00255401-01, AC-11160, AJ-08418, AN-23714, AS-12677, BC201828, BR-72920, LS-20589, SAM002554908, SC-16204, ST086740, SBI-0051636.P002, 2-(2,3-Dimethyl-phenylamino)-benzoic acid, AB0012318, AB1009470, ST2409237, 2-[(2,3-dimethylphenyl) amino]benzoic acid, 2-Diphenylaminecarboxylic acid,3'-dimethyl-, AB00052200, AM20060688, FT-0628184, UNM000001233403, 1-Methyl-3-benzylimidazolium tetrafluoroborate, C02168, D00151, M-6454, AB00052200-17, AB00052200_18, AB00052200_19, A833367, I14-3644, SR-01000000216-2, SR-01000000216-4, W-105113, BRD-K92778217-001-06-1, Z56755828, 2-(2,3-Dimethyl-phenylamino)-benzoic acid(Mefenamic acid), A1077/0050549, Mefenamic acid, European Pharmacopoeia (EP) Reference Standard, Mefenamic acid, United States Pharmacopeia (USP) Reference Standard, 4-methyl-N-(3-{3-[(4-methylpiperidin-1-yl)carbonyl]imidazo[2,1-b][1,3]thiazol-6-yl}phenyl)benzenesulfonamide, InChI=1/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18

ID: 907

InChIKey: HZEQBCVBILBTEP-ZFINNJDLSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.C1CNCCN1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5284555
synonyms found at PubChem are:
Estropipate, 7280-37-7, Piperazine estrone sulfate, Harmogen, Ogen, Ortho-Est, UNII-SVI38UY019, Piperazine estronesulfate, Sulestrex, SVI38UY019, Estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, compd. with piperazine (1:1), OGEN 2.5, Estropipate (USP), OGEN 5, Ogen (TN), OGEN .625, OGEN 1.25, EINECS 230-696-3, piperazine (8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl sulfate, Piperazine oestrone sulphate, Conjugated estrogens: piperazine estrone sulfate, Estrone hydrogen sulfate compound with piperazine (1:1), Estropipate [USP:INN:BAN], Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with piperazine (1:1), PubChem22728, NCGC00016682-02, DSSTox_CID_3005, D03IUY, CAS-7280-37-7, AC1NR4O7, DSSTox_RID_76828, DSSTox_GSID_23005, SCHEMBL21577, MLS002153957, Estrone sulfate piperazine salt, CHEBI:4873, CHEMBL1200980, DTXSID3023005, CTK8F9509, MolPort-006-167-814, HMS1570I17, HMS2097I17, HMS2232O19, HMS3714I17, BCP05424, HY-B1361, Tox21_113350, MFCD00867399, AKOS024457702, BCP9000662, CCG-220688, CM14419, CS-4818, Estropipate, >=98% (HPLC), powder, CC-27537, SMR001233296, AX8127548, AM20080957, ST24048920, D00948, 280E377, A837628, C-22322, SR-01000000235, SR-01000000235-5, Piperazine, compd. with estrone hydrogen sulfate (1:1) (8CI), 3-(Sulfooxy)-estra-1,3,5(10)-trien-17-one : piperazine (1:1), Estrone, hydrogen sulfate, compd. with piperazine (1:1) (8CI), Estropipate, United States Pharmacopeia (USP) Reference Standard, 17-oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1), Piperazine, compd. with 3-(sulfooxy)estra-1,3,5(10)-trien-17-one (1:1) (9CI), [(8R,9S,13S,14S)-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate; piperazine, [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate,piperazine, [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate; piperazine, 29080-16-8, piperazine; sulfuric acid [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] ester

ID: 908

InChIKey: HZHSVQVECJXVRP-UHFFFAOYSA-N
SMILES: CC(=O)OCC(CC(=O)CCCCCCCCCCCC#C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6710762
synonyms found at PubChem are:
AVOCADYNONE ACETATE, 1-Acetoxy-2-hydroxy-16-heptadecyn-4-one, 24607-10-1, 2-hydroxy-4-oxoheptadec-16-yn-1-yl acetate, KBio3_002773, Spectrum2_000300, Spectrum3_001856, Spectrum4_001264, Spectrum5_001604, AC1O8K1Y, BSPBio_003272, KBioGR_001848, SPECTRUM1505235, SPBio_000240, SCHEMBL4951546, CHEMBL1488011, CTK8H8026, CCG-39858, LMFA05000595, SDCCGMLS-0066756.P001, NCGC00095831-01, NCGC00095831-02, (2-hydroxy-4-oxoheptadec-16-ynyl) acetate, 1,2-Dihydroxy-16-heptadecyne-4-one 1-acetate, 16-Heptadecyn-4-one, 1,2-dihydroxy-, 1-acetate, 16-Heptadecyn-4-one, 1-(acetyloxy)-2-hydroxy-

ID: 909

InChIKey: HZQDCMWJEBCWBR-UUOKFMHZSA-N
SMILES: C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 104762
synonyms found at PubChem are:
mizoribine, 50924-49-7, Bredinin, Bredinine, Mizoribinum, Mizoribina, Mizoribine [INN:JAN], Mizoribinum [INN-Latin], Mizoribina [INN-Spanish], HE-69, UNII-4JR41A10VP, Bredinin (TN), MLS000028813, 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide, BRN 4151713, SMR000058473, 4-Carbamoyl-1-beta-D-ribofuranosyl-imidazolium-5-olate, 4JR41A10VP, HE 69, Anhydro-4-carbamoyl-5-hydroxy-1-beta-D-ribofuranosyl-imidazolium hydroxide, 4-carbamoyl-1-b-d-ribofuranosylimidazolium-5-olate, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide, 5-Hydroxy-1-beta-D-ribofuranosylimidazole-4-carboxamide, HS-0046, MZR, NCGC00094087-01, 1H-Imidazole-4-carboxamide, 5-hydroxy-1-beta-D-ribofuranosyl-, M 3047, DSSTox_CID_25777, DSSTox_RID_81119, DSSTox_GSID_45777, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide, 50524-49-7, N'-(beta-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide, N'-(beta-D-Ribofuranosyl)-5-hydroxy-imida-zole-4-carboxamide, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-1H-imidazole-4-carboxamide, CAS-50924-49-7, SR-01000075989, beta-Bredinin, Mizoribine(Bredinin), Mizoribine (Bredinin), Mizoribine (JAN/INN), Opera_ID_1558, Spectrum2_001559, Spectrum3_000739, Spectrum4_000220, Spectrum5_001671, D0G5AG, Mizoribine (JP17/INN), AC1L2XG8, SCHEMBL7118, Lopac0_000745, BSPBio_002298, KBioGR_000859, MLS001076272, MLS006010038, DivK1c_000948, SPBio_001438, 4-carbamoyl-1-beta-D-ribofuranosylimidazolium-5-olate, AC1Q5G14, CHEMBL245019, cid_104762, Mizoribine, >=98% (TLC), DTXSID8045777, BDBM68669, CHEBI:31858, CTK8G1133, HMS502P10, KBio1_000948, KBio3_001518, KS-00000XHM, HZQDCMWJEBCWBR-UUOKFMHZSA-N, MolPort-003-665-578, NINDS_000948, HMS2230D04, HMS3262E12, ZINC3812887, Tox21_111242, Tox21_500745, CCG-39778, MFCD00057221, QC-367, s1384, AKOS015994615, Tox21_111242_1, AC-5266, API0003412, BCP9000933, CS-1823, DB12617, LP00745, HE 69;NSC 289637;MZB;Bredinin, IDI1_000948, SMP1_000195, NCGC00094087-02, NCGC00094087-03, NCGC00094087-04, NCGC00094087-05, NCGC00261430-01, AK162477, BC678195, HY-17470, LS-78195, Q571, SC-79295, BCP0726000318, SBI-0050723.P003, AB0017672, AB2000078, AX8140206, EU-0100745, FT-0630635, FT-0652030, ST24048110, D01392, AB00053323_12, AB00053323_13, 924M497, Bredinin, HE 69, NSC 289637, MZB, Mizoribine, J-700185, SR-01000075989-1, SR-01000075989-4, 4-Carbamoyl-1-(beta-D-ribofuranosyl)-5-oxylatoimidazolium, 5-hydroxy-1-b-D-ribofuranosyl-1H-Imidazole-4-carboxamide, Bredinin, HE 69, NSC 289637, MZB, 50924-49-7, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-hydroxy-4-imidazolecarboxamide, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-imidazole-4-carboxamide, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-hydroxy-imidazole-4-carboxamide, 1-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-oxidanyl-imidazole-4-carboxamide, Bredinin|||HE-69|||NSC-289637|||1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide

ID: 910

InChIKey: HZVCEQMJXMUXJF-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957660
synonyms found at PubChem are:
NAFTOPIDIL DIHYDROCHLORIDE, 57149-08-3, Naftopidil DiHCl, 1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol dihydrochloride, C24H30Cl2N2O3, SR-01000002977, Naftopidil dihydrochloride [MI], Naftopidil dihydrochloride, (+/-)-, flivas dihydrochloride, KT-611 dihydrochloride, Naftopidil.Dihydrochloride, EU-0100941, SCHEMBL1322047, CHEMBL1593765, MolPort-003-958-925, HMS1571C11, KS-00000GR4, Tox21_500941, BN0361, s1387, AKOS015900296, API0007565, CCG-220975, CCG-222245, FE-0212, LP00941, MCULE-7806634031, 4-(2-Methoxyphenyl)-alpha-((1-naphthalenyloxy)methyl)-1-piperazineethanol dihydrochloride, NCGC00094247-01, NCGC00261626-01, 1-Piperazineethanol, 4-(2-methoxyphenyl)-alpha-((1-naphthalenyloxy)methyl)-, hydrochloride (1:2), AC-24018, TL8003680, FT-0672587, N-158, VU0612514-1, M02151, 149N072, A831328, I14-1084, SR-01000002977-2, SR-01000002977-4, SR-01000002977-10, SR-01000002977-11, F3368-0103, Flivas, KT-611, BM-15275, Avishot, 57149-08-3, 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthalenyloxy)-2-propanol dihydrochloride, 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol dihydrochloride, 1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthyloxy)-2-propanol dihydrochloride, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxy-propan-2-ol dihydrochloride

ID: 911

InChIKey: HZYRBUCNWBHBKG-UHFFFAOYSA-N
SMILES: C1CCC2=C(C1)C(=C(S2)NC(=O)NC3=CC=CC=C3)C(=O)N

biological descriptors:

reference list:

"AA Shelat" "H Yang" "T Ma" "LJ Galietta" "VS Gopinath" "GL Lukacs" "K Du" "AS Verkman" "RK Guy" "C Folli" "N Pedemonte" "A Taddei"

CID is 730612
synonyms found at PubChem are:
2-[(anilinocarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-[(phenylcarbamoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, BAS 02283611, AC1LE5JX, Cambridge id 6284183, TimTec1_003014, Oprea1_332571, Oprea1_467201, ARONIS021903, SCHEMBL5450860, HZYRBUCNWBHBKG-UHFFFAOYSA-N, MolPort-000-884-421, HMS1542I22, ZINC143445, KS-00004D9Z, STK008802, AKOS000281732, MCULE-6024236949, ST040702, BB0276176, KB-122439, AN-329/40173696, BRD-K65277491-001-01-5, Z44613029, 2-(N'-Phenylureido)-4,5,6,7-tetrahydro-benzo[b]thiophen-3-carbonsaureamid, 2-(phenylcarbamoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-[(anilinocarbonyl)amino]-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxamide, 2-[(phenylamino)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxami de, 27285-13-8

ID: 912

InChIKey: IADUEWIQBXOCDZ-VKHMYHEASA-N
SMILES: C1CN[C@@H]1C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 16486
synonyms found at PubChem are:
2133-34-8, (S)-Azetidine-2-carboxylic acid, L-Azetidine-2-carboxylic acid, (S)-(-)-2-Azetidinecarboxylic acid, (2S)-azetidine-2-carboxylic acid, Azetidyl-2-carboxylic acid, (S)-2-Azetidinecarboxylic acid, L-Azetidine 2-carboxylic acid, 2-Azetidinecarboxylic acid, (S)-, (S)-(-)-Azetidine-2-carboxylic acid, 2-Azetidinecarboxylic acid, L-, H-Aze-OH, Azetidine-2-carboxylic acid, L-, 2-Azetidinecarboxylic acid, (2S)-, L-azetidine-2-carboxylate, UNII-5GZ3E0L9ZU, 5GZ3E0L9ZU, (L)-AZETIDINE-2-CARBOXYLIC ACID, L-2-Azetidinecarboxylic acid, CHEBI:6198, Acide L-azetidine-2-carboxylic, CHEMBL1165239, HSDB 3465, (2S)azetidine-2-carboxylic acid, IADUEWIQBXOCDZ-VKHMYHEASA-N, EINECS 218-362-5, Azetidinecarboxylic acid, L-Trimethyleneimine-2-carboxylic Acid, (S)-(-) Azetidine-2-carboxylic acid, Acide L-azetidine-2-carboxylic [French], ST059592, azetidine-2-carboxylate, L-Azetidine-2-carboxylicacid, MFCD00800731, AzeOH, (2S)-(-)-Azetidine-2-carboxylic acid, 2-Azetidinecarboxylic acid, (S)- (9CI), L-AzeOH, PubChem5731, D00BFT, AC1Q71BN, L-azetidine-2caboxylic acid, (S)-Azetidin-2-carbonsaure, L-azetidine-2carboxylic acid, Lopac0_000023, SCHEMBL20296, KSC204E8D, (S)-2-azetidinecarboxyic acid, AC1L281R, GTPL4686, 2-(S)-azetidinecarboxylic acid, azetidine-2(S)-carboxylic acid, Jsp004347, L--Azetidine-2-carboxylic acid, DTXSID0044020, (2s)-2-azetidinecarboxylic acid, CTK1A4281, (S)-2-azetidine carboxylic acid, azetidine-2-(S)-carboxylic acid, MolPort-000-000-565, MolPort-044-811-434, BH277, HMS3260E07, HT707, ACT01799, KS-000008CF, KS-000008CG, ZINC1698540, (S)-(-)-2-Azetidinecarboxylicacid, (S)-L-Azetidine-2-carboxylic acid, Tox21_500023, ANW-49555, BDBM50357225, CA-217, FC0250, MFCD00005166, SBB004365, AKOS005254687, AKOS006239010, (S)-(-)-2-azetidine carboxylic acid, (S)-(-)-2-azetidine-carboxylic acid, AC-5699, AN-6443, CCG-204119, LP00023, RP08255, RTR-010012, L-Azetidine-2-carboxylic acid, >=99%, NCGC00093546-01, NCGC00093546-02, NCGC00093546-03, NCGC00260708-01, AJ-30369, BC201996, BR-59529, DS-16309, KB-53150, LS-23063, SC-02442, AB0005714, AB1011133, AM20090185, CS-0031389, EU-0100023, FT-0084527, FT-0636580, A 0760, A-2144, A50121, C08267, 133A348, SR-01000075656, SR-01000075656-1, W-107562, 2133-34-8 (S)-AZETIDINE-2-CARBOXYLIC ACID, UNII-775261TI36 component IADUEWIQBXOCDZ-VKHMYHEASA-N, CJ-28528

ID: 913

InChIKey: IAIWVQXQOWNYOU-FPYGCLRLSA-N
SMILES: C1=C(OC(=C1)[N+](=O)[O-])/C=N/NC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5447130
synonyms found at PubChem are:
nitrofurazone, Nitrofural, Furacilin, 59-87-0, Furacin, Furacillin, Aldomycin, Furacine, Furaldon, Nifuzon, Actin-N, Babrocid, Chemofuran, Furacinetten, Furacoccid, Furacycline, Furaziline, Furazone, Mastofuran, Monafuracin, Nitrofurazan, Nitrozone, Otofuran, Alfucin, Amifur, Furesol, Mammex, Furazol W, Becafurazone, Biofuracina, Dermofural, Furametral, Furaseptyl, Furatsilin, Fuvacillin, Monafuracis, Monofuracin, Nitrofurol, Biofurea, Cocafurin, Coxistat, Dynazone, Eldezol, Fedacin, Flavazone, Fracine, Furacort, Furaderm, Furagent, Furalone, Furaplast, Furaskin, Furazin, Furazina, Furazyme, Furfurin, Furosem, Hemofuran, Ibiofural, Nifucin, Nifurid, Otofural, Sanfuran, Vabrocid, Vadrocid, Yatrocin, Chixin, Nefco, 5-Nitro-2-furaldehyde semicarbazone, 5-Nitrofurazone, 5-Nitrofurfural semicarbazone, Furan-Ofteno, Spray-Dermis, Spray-Foral, Furacin-Hc, Nitrofuralum, Eldezol F-6, Furacilinum, Nitrofurane, Furacin-E, Nitrofuraldehyde semicarbazone, (5-Nitro-2-furfurylidenamino)urea, 5-Nitrofuraldehyde semicarbazide, Usaf ea-4, Nitrofurazonum, Fura-septin, Veterinary nitrofurazone, Nitrofuran (bactericide), NF-7, 6-Nitrofuraldehyde semicarbazide, 5-Nitro-2-furfural semicarbazone, 1-(5-Nitro-2-furfurylidene)semicarbazide, 5-Nitrofuran-2-aldehyde semicarbazone, Dymazone, Furalcyn, 5-Nitro-2-furfuraldehyde semicarbazone, NCI-C56064, 5-Nitro-2-furancarboxaldehyde semicarbazone, NSC-2100, UNII-X8XI70B5Z6, Nitrofural [INN], Semikarbazon 5-nitrofurfuralu, NFZ, Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]-, U-6421, 2-Furaldehyde, 5-nitro-, semicarbazone, Rivafurazon, Acutol, X8XI70B5Z6, 2-Furancarboxaldehyde, 5-nitro-, semicarbazone, NSC1602, NSC2100, Rivopon-5, component of Furea, (5-Nitro-2-furfurylideneamino)urea, Nitrofural (INN), 2-[(5-nitro-2-furyl)methylene]hydrazinecarboxamide, component of Furadex, 2((5-Nitro-2-furanyl)methylene)hydrazinecarboxamide, component of Furacort, Hydrazinecarboxamide, 2-((5-nitro-2-furanyl)methylene)-, NCGC00090686-04, NCGC00090686-07, 5-nitrofuran-2-carbaldehyde semicarbazone, [(E)-(5-nitro-2-furyl)methyleneamino]urea, DSSTox_CID_944, Nitrofuralum [INN-Latin], DSSTox_RID_75881, DSSTox_GSID_20944, [(E)-(5-nitrofuran-2-yl)methylideneamino]urea, 2-[(5-Nitro-2-furanyl)methylene]hydrazinecarboxamide, CCRIS 1195, NFS, WLN: T5OJ BNW E1UNMVZ, HSDB 3136, (2E)-2-[(5-nitrofuran-2-yl)methylidene]hydrazinecarboxamide, (E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide, NSC 1602, NSC 2100, 2-Furancarboxaldehyde, semicarbazone, EINECS 200-443-1, Semikarbazon 5-nitrofurfuralu [Polish], BRN 0086403, AI3-17333, SR-05000002027, 2-((5-Nitro-2-furanyl)methylene)hydrazinecarboxamide, N-[(1E)-2-(5-nitro(2-furyl))-1-azavinyl]aminoamide, CHEBI:44368, Nitrofurazone [USP:INN:BAN], Nfz mix, CAS-59-87-0, Prestwick_806, [(5-nitrofuran-2-yl)methylideneamino]urea, Furacin (TN), Nitrofurazone (USP), Furacin Topical Cream, PubChem7175, Furacin Soluble Dressing, Furacin Topical Solution, AC1NU7EL, AC1Q4ZSR, AC1Q5AZR, Prestwick2_000492, Prestwick3_000492, Spectrum5_001160, Nitrofurazone (Nitrofural), CHEMBL869, D0IE1E, SCHEMBL25416, SCHEMBL25417, BSPBio_000383, BSPBio_002075, MLS002153843, ARONIS24564, SPECTRUM1500434, BPBio1_000423, component of Furea (Salt/Mix), DTXSID5020944, component of Furadex (Salt/Mix), HMS502G20, IAIWVQXQOWNYOU-FPYGCLRLSA-N, MolPort-000-886-370, MolPort-006-012-954, HMS1569D05, HMS1920B04, HMS2091J04, HMS2096D05, HMS3713D05, Pharmakon1600-01500434, HY-B0226, NSC-1602, ZINC4802968, Tox21_110997, Tox21_202988, Tox21_400035, BDBM50420350, CCG-39642, MFCD00003225, NSC757244, s1644, SBB028409, STK741625, 1-(5-Nitrofurfurylidene)semicarbazide, 5-Nitro-2-furaldehyde, semicarbazone, AKOS000304771, Nitrofural;Furacilin;ACTIN-N;Otofuran, Tox21_110997_1, CS-2174, DB00336, LS41202, MCULE-5485227436, NSC-757244, RTR-032588, IDI1_000778, NCGC00090686-01, NCGC00090686-02, NCGC00090686-03, NCGC00090686-05, NCGC00090686-06, NCGC00090686-08, NCGC00090686-11, NCGC00260533-01, AC-10331, AN-23623, BC200619, H823, SC-05628, Semioxamazide, 1-(5-nitrofurfurylidene)-, SMR000059012, SBI-0051458.P003, AB2000189, ST4012758, TR-032588, AB00373885, N0200, C08042, D00862, AB00373885-04, AB00373885_05, AB00373885_06, [(E)-[(5-nitrofuran-2-yl)methylidene]amino]urea, Q-201480, SR-05000002027-1, SR-05000002027-3, BRD-K79092138-001-05-2, BRD-K79092138-001-06-0, 5-Nitro-2-furaldehyde semicarbazone, >=97.0% (HPLC), A0658/0030595, Nitrofural, European Pharmacopoeia (EP) Reference Standard, Nitrofurazone, United States Pharmacopeia (USP) Reference Standard, Nitrofural for peak identification, European Pharmacopoeia (EP) Reference Standard, Nitrofurazone solution, 100 mug/mL in acetonitrile, VETRANAL(TM), analytical standard, Nitrofurazone, Pharmaceutical Secondary Standard; Certified Reference Material, 60051-85-6, 8027-71-2

ID: 914

InChIKey: IAJBQAYHSQIQRE-UHFFFAOYSA-N
SMILES: COC1=CC(=C(C=C1C=O)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 20525
synonyms found at PubChem are:
2,4,5-TRIMETHOXYBENZALDEHYDE, 4460-86-0, Asaraldehyde, Asaronaldehyde, Asarylaldehyde, Azarylaldehyde, Benzaldehyde, 2,4,5-trimethoxy-, Gazarin, 3,4,6-Trimethoxybenzaldehyde, NSC 89299, NCI-C61632, UNII-NDU8J2Q00D, 14374-62-0, 2,4,5-trimethoxy-benzaldehyde, CCRIS 1296, HSDB 4502, EINECS 224-713-3, BRN 1951403, NDU8J2Q00D, AI3-36671, 2,4,5-Trimethoxy benzaldehyde, IAJBQAYHSQIQRE-UHFFFAOYSA-N, NCGC00091253-05, SMR000112148, Acrolein(Propenal), PubChem8263, Spectrum_000818, Spectrum2_000386, Spectrum3_000170, Spectrum4_001759, Spectrum5_000618, ACMC-1ADV9, DSSTox_CID_2217, 2,5-Trimethoxybenzaldehyde, 3,6-Trimethoxybenzaldehyde, AC1L2GG7, DSSTox_RID_76523, DSSTox_GSID_22217, Asaraldehyde (Asaronaldehyde), Asaraldehyde - Asaronaldehyde, BSPBio_001639, KBioGR_002238, KBioSS_001298, SPECTRUM200208, 4-08-00-02715 (Beilstein Handbook Reference), KSC236C5N, MLS002473312, MLS002695891, MLS006011864, 2,4,5-Trimethoxybenzaldheyde, SCHEMBL333451, SPBio_000571, 2,4,5-Trimethoxy-benzaldehyd, 3,4, 6-Trimethoxybenzaldehyde, AC1Q490G, PARAGOS 530447, CHEMBL1164301, DTXSID1022217, CTK1D6156, KBio2_001298, KBio2_003866, KBio2_006434, KBio3_001139, KS-00000KKZ, TIMTEC-BB SBB040214, CHEBI:113543, MolPort-000-871-193, Asarylaldehyde, analytical standard, BCPP000436, HMS1922P08, HMS2268O16, HMS3656M12, ZINC336939, BCP02914, NSC89299, AKOS BBS-00003175, Tox21_400070, ANW-30143, BBL011033, CCG-38657, LABOTEST-BB LT00926884, LABOTEST-BB LT03330935, LABOTEST-BB LT03381259, MFCD00003312, NSC-89299, s2531, SBB040214, STK802187, 2,4,5-Trimethoxybenzaldehyde, 98%, AKOS000119399, AC-4247, AS02818, BCP9000230, CS-6035, LS-1267, LS10199, MCULE-7174618286, PS-6109, RP25437, RTR-017129, SDCCGMLS-0066425.P001, TRA0030137, NCGC00091253-01, NCGC00091253-02, NCGC00091253-03, NCGC00091253-04, NCGC00091253-06, NCGC00091253-07, 4CA-0107, AJ-19817, AN-12166, KB-85563, SC-04555, ST093686, TL806230, ZB010841, 2,4,5-Trimethoxybenzaldehyde, 9CI, 8CI, BCP0726000304, CAS-4460-86-0, AB1004251, DB-051236, HY-100580, ST2415708, TR-017129, Asarylaldehyde, NSC 89299;4460-86-0, FT-0609813, 60T860, A26620, K-8969, AP-065/41884113, SR-05000002433, I01-1219, Q-100162, SR-05000002433-1, BRD-K88219015-001-02-5, BRD-K88219015-001-05-8, F2190-0582, 2,4,5-Trimethoxybenzaldehyde, Vetec(TM) reagent grade, 98%, InChI=1/C10H12O4/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-6H,1-3H

ID: 915

InChIKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N
SMILES: CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6167
synonyms found at PubChem are:
colchicine, 64-86-8, Colchicina, Colchicin, Colchisol, Condylon, Colcin, Colchicinum, Colchineos, Colsaloid, 7alphaH-Colchicine, Colcrys, (S)-colchicine, Colchicin [German], Colchysat, Goutnil, Kolkicin, spindle poison, Colchicina [Italian], 7-alpha-H-Colchicine, Colchicine [JAN], Colstat, NSC 757, UNII-SML2Y3J35T, Colchicine (TN), N-Acetyl trimethylcolchicinic acid methylether, CCRIS 691, Benzo(a)heptalen-9(5H)-one, Colchicine, Colchicum autumnale, NSC757, 7.alpha.H-Colchicine, HSDB 3044, (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide, EINECS 200-598-5, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, CHEMBL107, SML2Y3J35T, AI3-31149, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, CHEBI:27882, MPC-004, IAKHMKGGTNLKSZ-INIZCTEOSA-N, N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide, C22H25NO6, NCGC00025125-07, Colchicine, (R)-Isomer, DSSTox_CID_4845, Benzo(a)heptalen-9(5H)-one, 7-acetamido-6,7-dihydro-1,2,3,10-tetramethoxy-, C 9754, C-7100, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, DSSTox_RID_77551, N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide, DSSTox_GSID_24845, Mitigare, Acetamide, N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-, N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide, 30512-31-3, LOC, SMR000058323, Colchicine [USP:JAN], SR-01000075794, SR-01000597576, Colchicine, (+-)-Isomer, binds to tubulin, (S)-colchicina, 4lzr, (S)-colchicin, Acetamide,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(.alpha.)heptalen-7-yl)-, Acetamide,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-, N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)- acetamide, N-[(7s)-1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5h-Benzo[d]heptalen-7-Yl]ethanamide, CAS-64-86-8, Prestwick_695, Spectrum_000842, Tocris-1364, 4o2b, AC1L1LXO, Prestwick0_000363, Prestwick1_000363, Prestwick2_000363, Prestwick3_000363, Spectrum2_000075, Spectrum3_000362, Spectrum4_000298, Spectrum5_000787, Colchicine (JP15/USP), Colchicine (JP17/USP), Colchineos;Colchisol;Colcin, D09DHY, UPCMLD-DP065, EC 200-598-5, SCHEMBL8469, Lopac0_000310, BSPBio_000485, BSPBio_002083, inhibits microtubular assembly, KBioGR_000856, KBioSS_001322, MLS001055448, MLS001304089, MLS002153786, DivK1c_000753, SPECTRUM1500205, SPBio_000289, SPBio_002406, BPBio1_000535, GTPL2367, MEGxp0_001879, DTXSID5024845, UPCMLD-DP065:001, ACon1_000353, HMS502F15, KBio1_000753, KBio2_001322, KBio2_003890, KBio2_006458, KBio3_001303, NSC-757, MolPort-001-742-594, NINDS_000753, ZX-AFC000369, Colchicine, 95% dry weight 1g, HMS1569I07, HMS1920A08, HMS2091G16, HMS2096I07, HMS2231C05, HMS3260N22, HMS3713I07, Pharmakon1600-01500205, ZINC621853, Colchicine, >=96.0% (HPLC), Tox21_110947, Tox21_201547, Tox21_300582, Tox21_500310, BDBM50014846, BG0155, CCG-39910, KM0881, LS-279, NSC756702, AKOS001582887, Colchicine, >=95% (HPLC), powder, Tox21_110947_1, API0002098, CS-1141, DB08117, EBD2156734, LP00310, MCULE-1568647156, MCULE-7858118731, NSC-756702, RL04473, SDCCGMLS-0066633.P001, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(alpha)heptalen-7-yl)-, IDI1_000753, NCGC00025125-01, NCGC00025125-02, NCGC00025125-03, NCGC00025125-04, NCGC00025125-05, NCGC00025125-06, NCGC00025125-08, NCGC00025125-09, NCGC00025125-10, NCGC00025125-11, NCGC00025125-12, NCGC00025125-13, NCGC00025125-14, NCGC00025125-15, NCGC00025125-18, NCGC00025125-20, NCGC00169157-01, NCGC00169157-02, NCGC00169157-03, NCGC00254359-01, NCGC00259096-01, NCGC00260995-01, AN-16005, AS-13686, CC-25958, CJ-04376, HY-16569, NCI60_041659, SC-11404, ZB014630, SBI-0050298.P004, AB2000548, A3324, EU-0100310, FT-0603187, MLS001055448-02, N1721, C07592, D00570, J10109, M01514, 24218-EP2275412A1, 24218-EP2277865A1, 24218-EP2281815A1, 24218-EP2301933A1, 24218-EP2301940A1, 24218-EP2305219A1, 24218-EP2305640A2, 24218-EP2311827A1, 24218-EP2314590A1, binds to tubulin; inhibits microtubular assembly, 078C484, C-21700, SR-01000075794-1, SR-01000075794-3, SR-01000075794-6, SR-01000075794-7, SR-01000597576-1, SR-01000597576-3, BRD-K00259736-001-06-5, BRD-K00259736-001-10-7, WLN: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1, Benzo[a]heptalen-9(5H)-one,7-dihydro-1,2,3,10-tetramethoxy-, Colchicine, (European Pharmacopoeia (EP) Reference Standard), Colchicine, United States Pharmacopeia (USP) Reference Standard, Colchicine, BioReagent, plant cell culture tested, >=95% (HPLC), Colchicine, Pharmaceutical Secondary Standard; Certified Reference Material, (S)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide, (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl) acetamide, Colchicine for system suitability, European Pharmacopoeia (EP) Reference Standard, N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-acetamide, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide;, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]acetamide, 5843-86-7

ID: 916

InChIKey: IAKOZHOLGAGEJT-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4115
synonyms found at PubChem are:
methoxychlor, 72-43-5, p,p'-Methoxychlor, DMDT, Dimethoxy-DDT, Methoxy-DDT, Methoxcide, Metox, Maralate, Marlate, Moxie, Dianisyl trichloroethane, Metoksychlor, Higalmetox, Mezox K, Methoxychlor 2 ec, Dianisyltrichlorethane, Methoxychlore, Dimethoxy-DT, Rcra waste number U247, NCI-C00497, Caswell No. 550, Metoksychlor [Polish], 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane, 2,2-Bis(p-anisyl)-1,1,1-trichloroethane, ENT 1,716, Methoxychlor, technical, Methoxo, p,p'-DMDT, 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane, OMS 466, 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane, 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane, Methoxychlor [BSI:ISO], MeOCl, UNII-RIA79UD69L, Double-M ec, Methoxychlore [ISO-French], CCRIS 380, 2,2-Di-p-anisyl-1,1,1-trichloroethane, Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-, HSDB 1173, Methoxychlor [95%], 4,4-(2,2,2-Trichloroethylidene)dianisole, NSC 8945, Flo pro mcseed protectant, EINECS 200-779-9, p,p'-Dimethoxydiphenyltrichloroethane, Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-, p,p'-Dwumetoksydwufenylotrojchloroetan, 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane, 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane, 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane, RCRA waste no. U247, EPA Pesticide Chemical Code 034001, BRN 2057367, RIA79UD69L, 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene), Dimethoxydiphenyltrichloroethane, CHEBI:6842, Benzene, 1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-, 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-methoxybenzene), p,p'-Dwumetoksydwufenylotrojchloroetan [Polish], 2,2-Di(p-methoxyphenyl)-1,1,1-trichloroethane, 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane, 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan, p,p'-(Dimethoxydiphenyl)trichloroethane, NCGC00090760-08, 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German], Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy-, Di(p-methoxyphenyl)trichloromethyl methane, 1-Methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene, 2,2-Bis(4-methoxyphenyl)-1,1,1-trichloroethane, 1,1,1-Trichloro-2,2-bis-(p-methoxyphenyl)ethane, 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis[4-(methyloxy)benzene], SMR000568481, pMethoxychlor, Maxie, 4-methoxy-1-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene, Methoxy DDT, Mesox K, Chemform methoxychlor, Methoxychlor solution, Spectrum_001949, SpecPlus_000588, DSSTox_CID_827, Spectrum2_001890, Spectrum3_000864, Spectrum4_000704, Spectrum5_002050, AC1L1HG1, DSSTox_RID_75813, BIDD:PXR0108, DSSTox_GSID_20827, BSPBio_002507, KBioGR_001227, KBioSS_002503, SPECTRUM330077, MLS001055458, MLS001065605, BIDD:ER0613, DivK1c_006684, SCHEMBL116390, SPBio_001800, CHEMBL362919, Dimethox ydiphenyltrichloroethane, DTXSID9020827, CTK5D6098, KBio1_001628, KBio2_002495, KBio2_005063, KBio2_007631, KBio3_002007, Methoxychlor, analytical standard, WLN: GXGGYR DO1&R DO1, NSC8945, IAKOZHOLGAGEJT-UHFFFAOYSA-N, MolPort-003-665-467, PUBERTAL METHOXYCHLOR STUDY, HMS3039K10, ZINC155246, Marlate 300 flowable (Salt/Mix), NSC-8945, Tox21_400075, BDBM50410535, CCG-39337, MFCD00000803, SBB057311, p,p'-dimethoxydiphenyltrichl oroethane, AKOS001025493, Bis(p-anisyl)-1,1,1-trichloroethane, LS-1614, MCULE-1125841404, CAS-72-43-5, Methoxychlor 10 microg/mL in Isooctane, 1,1-Trichloro-2,2-bis(p-anisyl)ethane, NCGC00090760-01, NCGC00090760-02, NCGC00090760-03, NCGC00090760-04, NCGC00090760-05, NCGC00090760-06, NCGC00090760-07, NCGC00090760-09, NCGC00090760-10, NCGC00090760-11, CC-26448, MXC, ZB005997, di(p-methoxyphenyl) trichloromethyl methane, Methoxychlor 10 microg/mL in Acetonitrile, Methoxychlor 100 microg/mL in Cyclohexane, 2,2-Di(p-anisyl)-1,1,1-trichloroethane, Ethane,2-bis(p-anisyl)-1,1,1-trichloro-, Bis(p-methoxyphenyl)-1,1,1-trichloroethane, EU-0084224, FT-0603090, M1736, ST50997635, 1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane, 1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane, C11043, 1,2,2-Trichloroethylidene)bis(4-methoxybenzene), Methoxychlor, PESTANAL(R), analytical standard, 1,1,1-Trichloro-2,bis-[p-methoxyphenyl] ethane, 1,1-Bis(4-methoxyphenyl)-2,2,2-trichloroethane, 2,2-Bis (p-methoxyphenol)-1,1,1-trichloroethane, C-20487, Ethane,1,1-trichloro-2,2-bis(p-methoxyphenyl)-, 2,2,2-t richloro-1,1-bis(4-methoxyphenyl)ethane, I14-19578, Benzene,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-, 1,1'-(2,2,2-Trichloroethylidene)-bis[4-methoxybenzene], 4,4'-(2,2,2-trichloroethane-1,1-diyl)bis(methoxybenzene), Benzene, 1,1'-(2,2,2-trichloroethylidene)bis*4-methoxy-, Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-, KID PEST PROJECT (METHOXYCHLOR) (SEE ALSO METHOXYCHLOR), METHOXYCHLOR (SEE ALSO KID PEST PROJECT (METHOXYCHLOR)), 1-Methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene #, Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy- (9CI), Methoxychlor solution, 200 mug/mL in isooctane, analytical standard, methoxychlor (MXC) (1,1,1-trichloro-2,2-bis(p-methoxyphenyl)ethane), ENDOCRINE DISRUPTOR (METHOXYCHLOR) (SEE ALSO METHOXYCHLOR (72-43-5); KIDPEST PROJECT), InChI=1/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H

ID: 917

InChIKey: IAOZJIPTCAWIRG-QWRGUYRKSA-N
SMILES: COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 134601
synonyms found at PubChem are:
aspartame, 22839-47-0, Nutrasweet, Asp-phe-ome, Asp-Phe methyl ester, Aspartam, Aspartamum, Aspartamo, L-Aspartyl-L-phenylalanine methyl ester, Aspartylphenylalanine methyl ester, Dipeptide sweetener, Canderel, Methyl aspartylphenylalanate, Sweet dipeptide, 1-Methyl N-L-alpha-aspartyl-L-phenylalanate, Aspartam [INN-French], Aspartame, L,L-alpha-, Aspartamum [INN-Latin], Aspartamo [INN-Spanish], UNII-Z0H242BBR1, 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid, H-Asp-Phe-OMe, CCRIS 5456, CHEBI:2877, N-L-alpha-Aspartyl-L-phenylalanine 1-methyl ester, 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, SC 18862, HSDB 3915, Methyl L-aspartyl-L-phenylalanine, EINECS 245-261-3, Methyl L-alpha-aspartyl-L-phenylalanate, methyl L-alpha-aspartyl-L-phenylalaninate, L-Phenylalanine, N-L-alpha-aspartyl-, 1-methyl ester, Z0H242BBR1, Methyl N-L-alpha-aspartyl-L-phenylalaninate, 1-Methyl N-L-alpha-aspartyl-L-phenylalanine, (S)-3-Amino-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid, NCGC00091104-02, DSSTox_CID_107, E 951, 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, stereoisomer, DSSTox_RID_75371, Succinamic acid, 3-amino-N-(alpha-carboxyphenethyl)-, N-methyl ester, stereoisomer, DSSTox_GSID_20107, Sanecta, SC-18862, L-Phenylalanine, L-alpha-aspartyl-, 2-methyl ester, N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER, (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid, (S)-3-amino-4-((S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid, 7421-84-3, APM;Canderel;L-alpha-aspartyl-L-phenylalanine-methylester;(S)-3-Amino-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid, SMR000471870, CAS-22839-47-0, N-L-alpha-Aspartyl-L-phenylalanine methyl ester, Palsweet Diet, Pal Sweet, Aspartame [USAN:INN:BAN:NF], NCGC00095160-01, Aspartame (NF/INN), Spectrum2_001706, Spectrum3_001949, D00MFA, Epitope ID:164026, AC1L34VS, AC1Q41IK, SCHEMBL3636, BSPBio_003549, MLS001066421, MLS001306461, Aspartame, analytical standard, SPECTRUM1505306, SPBio_001692, CHEMBL171679, Jsp004609, DTXSID0020107, Asp-Phe methyl ester, >=98%, KBio3_002839, KS-00000AID, IAOZJIPTCAWIRG-QWRGUYRKSA-N, MolPort-001-792-024, aspartyl-phenylalanine methyl ester, HMS1922B16, HMS2093B05, HMS2233D15, Pharmakon1600-01505306, HY-B0361, ZINC1532132, Tox21_111080, Tox21_111459, Tox21_202315, Tox21_302965, CCG-39444, GE0967, MFCD00002724, NSC758953, s2036, SBB006713, AKOS015920055, L-Aspartyl-L-phenylalanyl methyl ester, Tox21_111080_1, AM84801, CS-2418, DB00168, MCULE-7493691716, NSC-758953, alpha-aspartyl-phenylalanine methyl ester, L-aspartyl-L-phenyl-alanine methyl ester, NCGC00091104-01, NCGC00091104-03, NCGC00091104-04, NCGC00091104-05, NCGC00095160-03, NCGC00256407-01, NCGC00259864-01, AC-12293, AJ-26753, AK-47609, AS-13889, BR-47609, E951, OR350295, SC-17477, SY012642, L-Aspartyl-L-3-phenylalanine methyl ester, SBI-0206757.P001, AB0058040, AB2000441, Asp-Phe methyl ester, >=99.0% (HPLC), TC-308713, A0997, AM20060556, FT-0627714, ST24032106, alpha-L-Aspartyl-L-Phenylalanine Methyl Ester, L-Aspartyl-L-phenylalanine methyl ester, 96%, N-L-alpha-Aspartyl-L-phenylalanineMethylEster, 39A470, C11045, D02381, M-4739, AB00376622_08, AB00376622_09, N-(L-alpha-Aspartyl)-L-phenylalanine methyl ester, SR-05000001682, TRANSGENIC MODEL EVALUATION II (ASPARTAME), J-502447, SR-05000001682-1, BRD-K78841970-001-06-2, Aspartame, European Pharmacopoeia (EP) Reference Standard, Aspartame, United States Pharmacopeia (USP) Reference Standard, (S)-3-amino-n-((s)-1-methoxycarbonyl-2-phenyl-ethyl)-succinamic acid, ASPARTAME (SEE ALSO (TRANSGENIC MODEL EVALUATION II (ASPARTAME)), Aspartame, Pharmaceutical Secondary Standard; Certified Reference Material, (3S)-3-{N-[(1S)-1-(methoxycarbonyl)-2-phenylethyl]carbamoyl}-3-aminopropanoic acid, (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid, 172964-81-7, 53906-69-7, VA10334, CJ-05239, CJ-24150

ID: 918

InChIKey: IBAQFPQHRJAVAV-ULAWRXDQSA-N
SMILES: C1[C@@H]([C@H]([C@@H]([C@H](N1CCO)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 441314
synonyms found at PubChem are:
MIGLITOL, 72432-03-2, Glyset, Diastabol, (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, Miglitolum, Plumarol, Seibule, Bay-m-1099, UNII-0V5436JAQW, Miglitol (Glyset), Glyset (TN), CHEMBL1561, 0V5436JAQW, CHEBI:6935, Bay m 1099, Miglitolum [Latin], SK-983, DSSTox_CID_3323, DSSTox_RID_76977, DSSTox_GSID_23323, Bay 1099, 1,5-dideoxy-1,5-[(2-hydroxyethyl)imino]-D-glucitol, C8H17NO5, EINECS 276-661-6, N-(2-Hydroxyethyl)-1-deoxynojirimycin, SMR000466381, CAS-72432-03-2, (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol, 1,5-Dideoxy-1,5-((2-hydroxyethyl)imino)-D-glucitol, Miglitol [USAN:INN:BAN], HSDB 8022, NCGC00095127-01, PubChem6069, PubChem21444, baym1099, AC1L9AYD, Bay m1009, D0D0ZD, SCHEMBL22593, Miglitol (JAN/USAN/INN), MLS000759514, MLS001424128, MLS006011963, BIDD:GT0732, cid_441314, GTPL4842, Miglitol (JP17/USAN/INN), DTXSID0023323, CTK8G1117, AOB5559, SYN3027, MolPort-006-069-197, HMS2051D05, HMS3713J07, N-hydroxylethyl-1-deoxynojirimycin, 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))-, HY-B0481, ZINC4097426, Tox21_111436, BDBM50242271, AKOS015969689, N-(b-Hydroxyethyl)-1-deoxynojirimycin, Tox21_111436_1, ACN-040712, CCG-100920, CS-2596, DB00491, KS-1242, MCULE-2158237443, NC00170, NE45506, RL04761, NCGC00270540-02, CPD000466381, K230, SAM001246745, SC-02811, AB0014109, AB2000682, FT-0628946, M2302, S2589, C07708, D00625, AB00639982-06, AB00639982_08, 432M032, A837526, SR-01000759413, SR-01000759413-4, W-104490, BRD-K44779798-001-06-5, Z1541638520, (2R,3R,4R,5S)-1-ethoxy-2-(hydroxymethyl)piperidine-3,4,5-triol, (2R,3R,4R)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-piperidine-3,4-diol, (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(2-hydroxymethyl)-3,4,5-piperidinetriol

ID: 919

InChIKey: IBBLRJGOOANPTQ-JKVLGAQCSA-N
SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 54891
synonyms found at PubChem are:
QUINAPRIL HYDROCHLORIDE, Accupril, 82586-55-8, Accuprin, Acequin, Quinazil, Korec, QUINAPRIL HCL, Hemokvin, Lidaltrin, Acuitel, Ectren, Conan, CI-906, Accupron, Acuprel, Continucor, Asig, Quinapril (hydrochloride), Accupro, Accuretic, Koretic, Quinapril.HCl, UNII-33067B3N2M, HSDB 7046, CI906, Quinapril hydrochloride, PD 109452-2, CHEBI:8714, Quinapril hydrochloride (Accupril), 33067B3N2M, Accupril (TN), DSSTox_CID_1221, DSSTox_RID_76019, DSSTox_GSID_21221, (3S)-2-[(2S)-2-{[(2S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YL]AMINO}PROPANOYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE, (S)-2-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 1-ethyl ester, monohydrochloride, (3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride, (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Hydrochloride, (3S-(2(R*(R*)),3R*))-2-(2-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID MONOHYDROCHLORIDE, (S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride, 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (3S-(2(R*(R*)),3R*))-, 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*)), CAS-82586-55-8, Quinapril hydrochloride [USAN], Quinapril N-Oxide, NCGC00094997-01, (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride, Quinapril hydrochloride [USAN:USP], CI 906, Quinapril hydrochloride;, AC1L1HXI, PD-109,452-2, SCHEMBL41404, MLS001076683, C25H30N2O5.HCl, Quinapril Hydrochloride ,(S), SPECTRUM1503076, CHEMBL1201011, DTXSID3021221, IBBLRJGOOANPTQ-JKVLGAQCSA-N, MolPort-003-666-434, HMS1922C15, Pharmakon1600-01503076, tetrahydroisoquinoline-3-carboxylic, HY-B0477, quinapril hydrochloride hydrochloride, 2-ylamino)propanoyl)-1,2,3,4-, Tox21_111381, Tox21_200390, CCG-39543, MFCD00889215, NSC758222, Quinapril hydrochloride (JP17/USP), s2581, AKOS015888532, Tox21_111381_1, AB07655, AC-1655, CS-2591, MCULE-2623123657, NC00722, NE45380, NSC-758222, NCGC00167962-06, NCGC00257944-01, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, 3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3S-(2(R*(R*)),3R*))-, AN-14706, AS-14026, BC206223, CPD000499582, LS-85471, SAM002589972, SC-17215, SMR000499582, AB2000675, PD-109522, CI-906 (CN-109452), C07340, D00459, Quinapril hydrochloride, >=98% (HPLC), solid, 586Q558, SR-01000765404, SR-01000765404-2, (S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-, monohydrochloride,(3s-(2(r*(r*)),3r*))-henylpropyl)amino)-1-oxopropyl), Quinapril hydrochloride, European Pharmacopoeia (EP) Reference Standard, Quinapril hydrochloride, United States Pharmacopeia (USP) Reference Standard, 3-isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-2-(2-((1-(ethoxycarbonyl)-3-p, Quinapril for peak identification, European Pharmacopoeia (EP) Reference Standard, Quinapril for system suitability, European Pharmacopoeia (EP) Reference Standard, (3S)-2-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride, (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride, (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride, (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride, (S)-2-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride, (S)-2-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid 1-Ethyl Ester Hydrochloride, [3S-[2[R*(R*)], 3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride, 3-isoquinolineacrboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, (3S-(2(R*(R*)),3R*))-

ID: 920

InChIKey: IBNAJETZECTKHN-DYWKTHLTSA-N
SMILES: COC1=CC2=C(C[C@@H]3[C@H]4[C@@]2(CCCC4)CCN3)C=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11565569
synonyms found at PubChem are:
3-Methoxy-morphanin hydrochloride, EU-0100864, SCHEMBL1616880, CHEMBL1515001, nor-Dextromethorphan hydrochloride, IBNAJETZECTKHN-DYWKTHLTSA-N, (+)-3-methoxy-morphinan hydrochloride, LP00864, NCGC00094189-01, LS-193174, M-187, SR-01000075459, SR-01000075459-1, 3-METHOXYMORPHINAN HYDROCHLORIDE (NOR-DE XTROMETHORPHAN, (+)-cis-1,3,4,9,10,10a-Hexahydro-6-methoxy-2H-10,4a-iminoethanophenanthrene

ID: 921

InChIKey: IBSREHMXUMOFBB-BKNUBRDCSA-N
SMILES: CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)CC=C([C@H]([C@H](C=CC=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)C)C.C[C@H]1C=CC=C2CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](CC=C([C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C(C)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 71308143
synonyms found at PubChem are:
avermectin B1 (CAS name)

ID: 922

InChIKey: ICTXHFFSOAJUMG-SLHNCBLASA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3CCC(=O)C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6231
synonyms found at PubChem are:
norethynodrel, Noretynodrel, Norethinodrel, 68-23-5, Lynestrol, 19-Norethynodrel, Enidrel, SC-4642, Noretinodrel [DCIT], 17-Ethinyl-5(10)-estraeneolone, 19-Nor-ethinyl-5,10-testosterone, Noretynodrelum [INN-Latin], NSC-15432, CCRIS 486, UNII-88181ACA0M, MLS000069824, HSDB 2951, 17alpha-Ethinyl-5,10-estrenolone, 17-alpha-Ethinyl-5,10-estrenolone, EINECS 200-682-1, NSC 15432, Norethynodrel [Progestins], CB 8023, BRN 2389771, Norethinynodrel, Norethynodral, CHEBI:34895, 17alpha-Ethynyl-5(10)-estren-17-ol-3-one, 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, 17-alpha-Ethynyl-5(10)-estren-17-ol-3-one, ICTXHFFSOAJUMG-SLHNCBLASA-N, 17alpha-Ethinyl-5(10)estraen-17beta-ol-3-one, 88181ACA0M, 17alpha-Ethynyl-estr-5(10)-en-3-on-17beta-ol, 17-alpha-Ethynyl-17-hydroxyestr-5(10)-en-3-one, 17-alpha-Ethynyl-estr-5(10)-en-3-on-17-beta-ol, 17alpha-Ethinyl-delta(sup)-5,10-19-nortestosterone, 17alpha-Ethynyl-17beta-hydroxyestr-5(10)-en-3-one, Noretynodrel (INN), Noretynodrel [INN], Estr-5(10)-en-3-one, 17alpha-ethynyl-17-hydroxy-, 17-alpha-Ethinyl-delta(super)-5,10-19-nortestosterone, 17-beta-Hydroxy-17-alpha-ethinyl-5(10)-estren-3-one, 17-Hydroxy(17alpha)-19-norpregn-5(10)-en-20-yn-3-one, 17-Hydroxy-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17alpha-Ethynyl-19-nor-5(10)-androsten-17beta-ol-3-one, SMR000058915, (17-alpha)-17-Hydroxy-19-norpregn-5(10)-en-20-yn-3-one, 17-alpha-Ethynyl-19-nor-5(10)-androsten-17-beta-ol-3-one, 17alpha-Ethinyl-17beta-hydroxy-delta(sup 5(10))-estren-3-one, 17alpha-Ethinyl-19-nor-delta-5(10)-androstene-17beta-ol-3one, 17alpha-Ethynyl-17beta-hydroxy-delta(sup 5(10))-estren-3-one, 19-Nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17-hydroxy-, 17-alpha-Ethinyl-17-beta-hydroxy-delta(sup 5(10))-estren-3-one, 17-alpha-Ethynyl-17-beta-hydroxy-3-oxo-delta(sup 5(10))-estrene, 17-alpha-Ethynyl-17-beta-hydroxy-delta(sup. 5(10))-estren-3-one, 17alpha-Ethynyl-17beta-hydroxy-3-oxo-delta(sup 5(10))-estrene, (8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta(a)-phenanthrene-3-one, (17beta)-17-ethynyl-17-hydroxyestr-5(10)-en-3-one, Noretinodrel, Noretynodrelum, 19-Nor-17-alpha-pregn-5(10)-en-20-yn-3-one, 17-hydroxy-, Norethynodrel [USAN:BAN], Norethynodrel [USAN:USP], Norethylnodrel, NSC15432, 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17.alpha.)-, CAS-68-23-5, NCGC00016304-01, Prestwick_883, Norethynodrel (USP), 17-Ethynyl-17-hydroxyestr-5(10)-en-3-one, DSSTox_CID_563, Opera_ID_1052, Prestwick0_000024, Prestwick1_000024, Prestwick2_000024, Prestwick3_000024, 17-.alpha.-Ethynyl-17-hydroxyestr-5(10)-en-3-one, 17.alpha.-Ethinyl-.DELTA.5(10)-19-nortestosterone, 17-.alpha.-Ethinyl-.DELTA.5(10)-19-nortestosterone, 17.alpha.-Hydroxy-19-norpregn-5(10)-en-20-yn-3-one, 5(10)-Estren-3-one, 17alpha-ethynyl-17beta-hydroxy-, AC1L1M2U, 17.alpha.-Ethinyl-.delta.(sup)-5,10-19-nortestosterone, CHEMBL1387, DSSTox_RID_75927, DSSTox_GSID_21069, SCHEMBL37838, BSPBio_000087, 17-.alpha.-Ethynyl-17-.beta.-hydroxy-5(10)-estren-3-one, 17-.beta.-Hydroxy-17-.alpha.-ethinyl-5(10)-estren-3-one, BIDD:ER0192, SPBio_002008, (17-.alpha.)-17-Hydroxy-19-norpregn-5(10)-en-20-yn-3-one, 17-.alpha.-Ethynyl-17-.beta.-hydroxy-.DELTA.5(10)-estren-3-one, 17.alpha.-Ethinyl-17.beta.-hydroxy-.DELTA.5(10)-estren-3-one, 17.alpha.-Ethynyl-17.beta.-hydroxy-.DELTA.5(10)-estren-3-one, 17.alpha.-Ethynyl-17.beta.-hydroxy-3-oxo-.DELTA.5(10)-estrene, BPBio1_000097, DTXSID3021069, 17-Ethynyl-17-hydroxyestr-.DELTA.5(10)-en-3-one, (17.alpha.,17.beta.)-, MolPort-006-147-720, HMS1568E09, HMS2095E09, HMS2232J10, HMS3712E09, 13-methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15h-cyclopenta[a]phenanthren-3-one, Tox21_110359, BDBM50410507, AKOS026749810, ZINC118913164, API0003629, CCG-220024, LS-7624, NCGC00179666-01, C14249, D05207, WLN: L E5 B666OV MUTJ E1 F1UU1 QQ, (17beta-ethynyl-17-hydroxyestr-5(10)-en-3-one, SR-01000721945, SR-01000721945-2, BRD-K80334323-001-03-5, Estr-5(10)-en-3-one,17.alpha.-ethynyl-17-hydroxy-, (17|A)-17-hydroxy-19-Norpregn-5(10)-en-20-yn-3-one, 17-Hydroxy-19-nor-17|A-pregn-5(10)-en-20-yn-3-one, 17-hydroxy-19-nor-17alpha-pregn-5(10)en-20-yn-3-one, 19-Nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17-hydroxy- (8CI)

ID: 923

InChIKey: ICVKYYINQHWDLM-KBEWXLTPSA-N
SMILES: CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 60196281
synonyms found at PubChem are:
Tylosin (tartrate), UNII-5P4625C51T, Tylan soluble, 5P4625C51T, Tylosin tartrate (USP), Tylosin tartrate [USP], DSSTox_CID_25938, DSSTox_RID_81236, DSSTox_GSID_45938, CAS-74610-55-2, Tylan injectable, NCGC00095162-01, Tylosin tartrate [MART.], Tylosin tartrate [WHO-DD], CHEMBL3189100, DTXSID3045938, Tylosin tartrate [GREEN BOOK], MolPort-030-084-352, HY-B0519, C46H77NO17.C4H6O6, Tox21_111461, Tox21_113372, 2772AH, s3162, AKOS030485973, CCG-213385, CS-2732, D10033, Tylosin tartrate, potency: >=800 units/mg tylosin, Tylosin tartrate, VETRANAL(TM), analytical standard, Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1), Tylosin tartrate, powder, BioReagent, suitable for cell culture, (2R,3R)-2,3-dihydroxybutanedioic acid;2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy, 61913-18-6, 65608-64-2, 8075-70-5, Tylosin solution, 8 mg/mL in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture

ID: 924

InChIKey: ICYQAMNVLLHURR-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C(=O)NCC2=CN=CC=C2)C(=O)NCC3=CN=CC=C3.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6419975
synonyms found at PubChem are:
Picotamide monohydrate, UNII-643HY5UHKS, Plactidil, 643HY5UHKS, 80530-63-8, Prestwick_539, Picotamide monohydrate [EP], SR-01000076086, AC1O4WH9, MLS002154203, SCHEMBL2916058, CHEMBL1317747, DTXSID30230378, HMS1568G20, HMS2095G20, HMS2231L12, HMS3372B17, HMS3712G20, N,N'-Bis(3-Pyridylmethyl)-4-methoxyisophthalamide monohydrate, CCG-220119, 1,3-Benzenedicarboxamide, 4-methoxy-N,N'-bis(3-pyridinylmethyl)-, monohydrate, 1,3-Benzenedicarboxamide, 4-methoxy-n1,n3-bis(3-pyridinylmethyl)-, hydrate (1:1), NCGC00017138-01, NCGC00017138-02, SMR001233489, CAS-80530-63-8, SR-01000076086-5, 4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide hydrate

ID: 925

InChIKey: IDDIJAWJANBQLJ-UHFFFAOYSA-N
SMILES: CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 62881
synonyms found at PubChem are:
Deferoxamine mesylate, 138-14-7, Desferrioxamine B mesylate, Desferal, Deferoxamine mesilate, Desferrioxamine mesylate, Desferal mesylate, Deferoxamine B mesylate, Deferoxamine methanesulfonate, Desferrioxamine methanesulfonate, Deferoxamine (mesylate), Desferal methanesulfonate, Deferoxamine mesylate salt, UNII-V9TKO7EO6K, DFX mesylate, Desferioxamine mesylate, EINECS 205-314-3, Ba 33122, V9TKO7EO6K, Desferrioxamine mesylate salt, Desferrioxamine B methanesulfonate, DESFERRIOXAMINE MESILATE, MLS000028713, Deferoxamine methanesulfonate salt, NCGC00017021-01, CAS-138-14-7, Desferal (TN), Deferoxamine-D8 mesylate, DSSTox_CID_17649, DSSTox_RID_79351, DSSTox_GSID_37649, N-(5-(3-((5-Aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(N-hydroxyacetamido)pentyl)carbamoyl)propionohydroxamic acid monomethanesulfonate (salt), CHEBI:31460, Butanediamide, N'-(5-((4-((5-(acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxy-, monomethanesulfonate, Propionohydroxamic acid, N-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(N-hydroxyacetamido)pentyl)carbamoyl)-, monomethanesulfonate (salt), NSC644468, SR-01000695424, SMR000058548, 138D147, Deferoxamine mesylate [USAN], CCRIS 8311, C25H48N6O8.CH4O3S, Deferoxamine mesylate [USAN:USP], Prestwick_988, Deforoxamine B mesylate, AC1Q5IOG, D0FJ8A, AC1L1XZ1, CHEMBL1234, Deferoxamine mesylate (USP), KSC959A0B, SCHEMBL119982, SPECTRUM1500224, Deferoxamine mesilate (JP17), Deferrioxamine B methanesulfonate, DTXSID6037649, CTK8F9000, HMS500E04, C26H52N6O11S, IDDIJAWJANBQLJ-UHFFFAOYSA-N, MolPort-003-666-154, HMS1570A12, HMS1920C16, HMS2091K08, HMS2097A12, HMS2234H23, HMS3714A12, Pharmakon1600-01500224, HY-B0988, Tox21_110741, CCG-39770, MFCD00058605, NSC756718, AKOS026750165, Tox21_110741_1, CS-4479, NSC 644468, NSC-644468, NSC-756718, NCGC00017021-02, NCGC00017021-03, NCGC00094640-01, NCGC00094640-02, NCGC00178802-06, AN-43810, BC667333, AB0035971, LS-124966, FT-0603121, ST24046423, Y0490, D01186, A807339, SR-01000695424-2, SR-01000695424-3, SR-01000695424-4, Deferoxamine mesylate salt, powder, >=92.5% (TLC), I14-98954, Deferoxamine mesylate salt, European Pharmacopoeia (EP) Reference Standard, Deferoxamine mesylate, United States Pharmacopeia (USP) Reference Standard, Deferoxamine for system suitability, European Pharmacopoeia (EP) Reference Standard, 17688-38-9, 35908-62-4, N'-(5-azanylpentyl)-N-[5-[[4-[5-[ethanoyl(oxidanyl)amino]pentylamino]-4-oxidanylidene-butanoyl]-oxidanyl-amino]pentyl]-N'-oxidanyl-butanediamide; methanesulfonic acid, N'-{5-[acetyl(hydroxy)amino]pentyl}-N-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-N-hydroxysuccinamide methanesulfonate (salt), n'-{5-[acetyl(hydroxy)amino]pentyl}-n-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-n-hydroxysuccinamide methanesulfonate(1:1), N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-1,4-dioxobutyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide; methanesulfonic acid, N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide; methanesulfonic acid, N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;methanesulfonic acid, N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic Acid Methanesulfonate, N1-(5-aminopentyl)-N1-hydroxy-N4-(5-(N-hydroxy-4-(5-(N-hydroxyacetamido)pentylamino)-4-oxobutanamido)pentyl)succinamide methanesulfonate, N1-(5-aminopentyl)-N1-hydroxy-N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]butanediamide Methanesulfonate, N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate, N4-[5-[[4-5-(Acetylhydroxyamino)pentyl]-1,4-dioxobutyl]hydroxyaminopentyl-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate, N'-{5-[acetyl(hydroxy)amino]pentyl}-N-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N-hydroxybutanediamide methanesulfonate

ID: 926

InChIKey: IDIIJJHBXUESQI-DFIJPDEKSA-N
SMILES: COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 101526
synonyms found at PubChem are:
Moxifloxacin hydrochloride, 186826-86-8, Moxifloxacin HCl, Avelox, Avalox, Vigamox, Moxifloxacin (Hydrochloride), Actira, Izilox, UNII-C53598599T, Bay-12-8039, CHEBI:7008, Moxifloxacine hydrochloride, AVELOX IN SODIUM CHLORIDE 0.8% IN PLASTIC CONTAINER, CPD000469185, C53598599T, Vigamox (TN), Avelox (TN), DSSTox_CID_25921, DSSTox_RID_81224, DSSTox_GSID_45921, (4aS-cis)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolol(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride, Octegra, MFLX, 1-Cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid HCl, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-, monohydrochloride, CAS-186826-86-8, Moxivig, Vegamox, Moxifloxacin hydrochloride [USAN], Moxifloxacin, HCl, NCGC00095130-01, 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, 1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid;hydrochloride, BAY-128039, BAY12-8039, Moxifloxacin hydrochloride [USAN:USP], 192927-63-2, cc-97, AC1L2R0P, C21H25ClFN3O4, SCHEMBL37285, C21H24FN3O4.HCl, MLS001401368, CHEMBL1200735, DTXSID4045921, IDIIJJHBXUESQI-DFIJPDEKSA-N, MolPort-005-934-227, ACT02692, BCP03623, Tox21_111439, CM0156, MFCD00949117, AKOS015920132, AKOS016015225, Tox21_111439_1, AC-1275, API0005432, BCP9000963, CCG-100924, CS-1063, KS-1181, Moxifloxacin hydrochloride (JAN/USAN), NC00174, RL02375, BAY 12-0839, NCGC00271749-02, AK-72941, AN-15101, AT-15459, BC205778, BR-72941, CC-31016, HY-66011, KB-78950, O381, SAM001246654, SMR000469185, BCP0726000173, AB0016427, LS-173737, Moxifloxacin hydrochloride, >=98% (HPLC), ST2413518, FT-0080006, FT-0082441, M2479, S1465, D00874, S-3681, 826M868, C-22335, 186826-86-8 151096-09-2(base), Moxifloxacin hydrochloride, VETRANAL(TM), analytical standard, Moxifloxacin hydrochloride, European Pharmacopoeia (EP) Reference Standard, Moxifloxacin for peak identification, European Pharmacopoeia (EP) Reference Standard, Moxifloxacin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Moxifloxacin hydrochloride, United States Pharmacopeia (USP) Reference Standard, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride, 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride (1:1), 1-Cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4, 1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-((4aS,7aS)-tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-,monohydrochloride, 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid hydrochloride, 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid hydrochloride, 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

ID: 927

InChIKey: IDPAEJSVXMLVBS-UHFFFAOYSA-N
SMILES: CN1C(CCCC1CC(C2=CC=CC=C2)O)CC(C3=CC=CC=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 197840
synonyms found at PubChem are:
Lobelanidine hydrochloride, LOBELANIDINE HCL, EINECS 228-076-2, MLS002153889, alpha,alpha'-Diphenyl-1-methyl-2,6-piperidinediethanol hydrochloride, AC1L544N, 1-Methyl-alpha,alpha'.-diphenylpiperidine-2,6-diethanol hydrochloride, 2,6-Piperidinediethanol, alpha,alpha'-diphenyl-1-methyl-, hydrochloride, CHEMBL1868990, HMS1569F06, SMR001233239, LS-114996, SR-01000841250, SR-01000841250-2, 2-[6-(2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl]-1-phenylethanol hydrochloride

ID: 928

InChIKey: IDYZIJYBMGIQMJ-UHFFFAOYSA-N
SMILES: CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3229
synonyms found at PubChem are:
enoxacin, 74011-58-8, Penetrex, Enoxacine, Comprecin, Enoxacino, Enoxacinum, Flumark, Bactidan, AT-2266, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid, Enoxor, Almitil, Enoram, Enoxin, Enoxacine [French], Enoxacinum [Latin], enofloxacin, CI-919, Enoxacino [Spanish], Enoksetin, CI 919, PD 107779, 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, Enoxacin (Penetrex), PD-107779, Enofloxacine, Bactidron, Enoxen, Penetrex (TN), NSC 629661, UNII-325OGW249P, CCRIS 5242, C15H17FN4O3, Enoxacin [USAN:BAN:INN:JAN], CHEBI:157175, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid, Enoxacin (USAN/INN), CHEMBL826, NSC 627409, BRN 3628995, IDYZIJYBMGIQMJ-UHFFFAOYSA-N, 325OGW249P, NSC629661, 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid, NCGC00016927-01, CAS-74011-58-8, E0762, DSSTox_CID_2984, 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, DSSTox_RID_76818, DSSTox_GSID_22984, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-1,8-naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-piperazinylhydropyridino[2,3-b]pyridine-3-carboxylic acid, SMR000058233, Sesquihydrate, Enoxacin, SR-01000000202, Enoxacina, Enoxacin [USAN:INN:BAN:JAN], Bactidron (TN), CI919, Comprecin (TN), Enoksetin (TN), Bactidan (TN), Prestwick_708, Almitil (TN), Enroxil (TN), Flumark (TN), Gyramid (TN), AT2266, Enoxen (TN), Enoxin (TN), Enoxor (TN), Vinone (TN), AT 2266, Spectrum_001539, PD107779, AC1L1FGQ, Prestwick0_000353, Prestwick1_000353, Prestwick2_000353, Prestwick3_000353, Spectrum2_001731, Spectrum3_001570, Spectrum4_000166, Spectrum5_001044, D0R8ER, Epitope ID:119069, Faulding Brand of Enoxacin, ENOXACIN pd107779, Oprea1_147866, SCHEMBL33963, BSPBio_000445, BSPBio_003080, Enoxacin, analytical standard, KBioGR_000651, KBioSS_002019, MLS000069645, MLS006011976, BIDD:GT0191, DivK1c_000420, SPECTRUM1503215, SPBio_001802, SPBio_002366, BPBio1_000491, GTPL8882, DTXSID5022984, BCBcMAP01_000009, CTK8E3243, HMS501E22, KBio1_000420, KBio2_002019, KBio2_004587, KBio2_007155, KBio3_002580, 8-naphthyridine-3-carboxylic acid, MolPort-003-666-456, NINDS_000420, HMS1569G07, HMS1922I17, HMS2090E10, HMS2092N20, HMS2233K20, HMS3372A12, HMS3655M08, HMS3715H13, Pharmakon1600-01503215, BCP22623, HY-B0268, Tox21_110688, BDBM50296358, CCG-39452, MFCD00133308, NSC758416, s1756, ZINC19594549, AKOS015838626, Tox21_110688_1, CL23362, CS-2257, DB00467, KS-5190, MCULE-2632820619, NE58656, NSC-629661, NSC-758416, IDI1_000420, SMP1_000113, NCGC00016927-02, NCGC00016927-03, NCGC00016927-04, NCGC00016927-05, NCGC00016927-06, NCGC00016927-07, NCGC00016927-08, NCGC00016927-10, NCGC00016927-11, NCGC00023864-03, NCGC00023864-04, NCGC00178309-01, NCGC00178309-02, AN-37251, K259, KB-87029, LS-95946, NCI60_009618, SC-13757, ST044514, SBI-0051788.P002, AB0014125, AB1011529, TL8005116, TR-037960, FT-0630825, Pierre Fabre Brand of Enoxacin Sesquihydrate, C06979, D00310, J10280, 1, 6-fluoro-1,4-dihydro- 4-oxo-7-piperazinyl, AB00052328-09, AB00052328_10, AB00052328_11, 011E588, A837996, I06-0290, Rhone Poulenc Rorer Brand of Enoxacin Sesquihydrate, Rhone-Poulenc Rorer Brand of Enoxacin Sesquihydrate, SR-01000000202-2, SR-01000000202-3, BRD-K78113049-001-05-5, BRD-K78113049-001-07-1, BRD-K78113049-001-12-1, Z1551429746, 84294-96-2 (.1.5H2O), 1,8-Naphthyridine-3-carboxylic acid, 6-fluoro-1,4-dihydro-4-oxo-7-piperazinyl, 1-ethyl-6-fluoranyl-4-oxidanylidene-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7- [1-piperazinyl]-1,8-naphthyridine-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid

ID: 929

InChIKey: IECBEVAUEBZJCF-SPIKMXEPSA-N
SMILES: C1CCN(CC1)CC2=CC(=CC=C2)OCCCNC3=NC4=CC=CC=C4S3.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957725
synonyms found at PubChem are:
Zolantidine dimaleate, SKF 95282 dimaleate, UNII-AL1YII70LM, AL1YII70LM, 104076-39-3, NCGC00094486-01, DSSTox_CID_25811, DSSTox_RID_81148, DSSTox_GSID_45811, SKF-95282 dimaleate salt, N-(3-(3-(1-Piperidinylmethyl)phenoxy)propyl)-2-benzothiazolamine dimaleate, N-[3-[3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYL]-2-BENZOTHIAZOLAMINE DIMALEATE, CAS-104076-39-3, SR-01000075175, CHEMBL1529009, DTXSID7045811, MolPort-003-983-446, HMS3263J12, Tox21_111285, Tox21_501245, AKOS024456368, Tox21_111285_1, CCG-222549, LP01245, NCGC00015957-06, NCGC00261930-01, 2-Benzothiazolamine, N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-, (2Z)-2-butenedioate (1:2), EU-0101245, S 5317, J-001100, SKF-95282 dimaleate salt, solid, >98% (HPLC), SR-01000075175-1, SR-01000075175-3, N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate; Zolantidine

ID: 930

InChIKey: IEDVJHCEMCRBQM-UHFFFAOYSA-N
SMILES: COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5578
synonyms found at PubChem are:
trimethoprim, 738-70-5, Proloprim, Trimpex, Bactramin, Monotrim, Monotrimin, Trimetoprim, Trimopan, Monoprim, Syraprim, Trimanyl, Wellcoprim, Triprim, Uretrim, 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, Sulfamethoprim, Trimethoprime, Trimethoprimum, Trimetoprima, Abaprim, Sulmeprim, 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine, Apo-Sulfatrim, Trimeth/Sulfa, Trimethioprim, Antrimox, Bacticel, Bactoprim, Bethaprim, Biosulten, Briscotrim, Chemotrin, Colizole, Cotrimel, Espectrin, Fermagex, Kombinax, Lagatrim, Metoprim, Novotrimel, Pancidim, Salvatrim, Sinotrim, Streptoplus, Sugaprim, Sulfamar, Sulfoxaprim, Sulthrim, Trimexol, Trimezol, Trisulcom, Trisulfam, Trisural, Urobactrim, Wellcoprin, Xeroprim, Zamboprim, Anitrim, Antrima, Bacdan, Bacidal, Bacide, Bencole, Conprim, Deprim, Duocide, Esbesul, Euctrim, Exbesul, Fortrim, Ikaprim, Lastrim, Omstat, Protrin, Purbal, Resprim, Roubac, Roubal, Setprin, Stopan, Sultrex, Toprim, Trimono, Trisul, Utetrin, Velaten, Bacin, Bacta, Cidal, component of Bactrim, Futin, Trimpex 200, Co-Trimoxizole, Lagatrim Forte, Septrin Forte, Alcorim-F, Colizole DS, Septrin S, Septrin DS, NIH 204, Smz-Tmp, Trimez-IFSA, U-Prin, component of Septra, Trimethopriom, Bactifor, Dosulfin, Instalac, Primsol, Trimetoprim [DCIT], Trimogal, Lescot, Tiempe, Trimetoprim [Polish], Resprim Forte, Uro-D S, Tmp Smx, 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine, NSC-106568, BW 56-72, Trimethoprime [INN-French], Trimethoprimum [INN-Latin], Trimetoprima [INN-Spanish], 2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-, Bacterial [Antibiotic], Trimexazole, Bacterial, Idotrim, Methoprim, Oraprim, Polytrim, Priloprim, Primosept, Alprim, Bactin, NIH 204 (VAN), Tmp-Ratiopharm, TCMDC-125538, Trimethopim(TMP), Proloprim (TN), UNII-AN164J8Y0X, Trimpex (TN), NSC 106568, WR 5949, CCRIS 2410, Sulfamethoxazole & Trimethoprim, 5-(3,4,5-Trimethoxybenzyl)-2,4-diaminopyrimidine, CHEBI:45924, HSDB 6781, CHEMBL22, 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine, Trimethoprim [USAN:BAN:INN:JAN], EINECS 212-006-2, BW 5672, 5-(3,4,5-Trimethoxybenzyl)-2,4-pyrimidinediamine, BRN 0625127, Pyrimidine, 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-, Trimethoprim (JAN/USP/INN), AI3-52594, MLS000079023, AN164J8Y0X, 2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)-methyl)-, 2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)methyl)-, IEDVJHCEMCRBQM-UHFFFAOYSA-N, KUC103659N, KSC-4-158, NSC106568, AZT + TMP/SMX (mixture) combination, NCGC00016055-05, 5-((3,4,5-Trimethoxyphenyl)methyl)-2,4-pyrimidinediamine, BW-56-72, CAS-738-70-5, SMR000035999, Trimethoprim sulfate, DSSTox_CID_3712, T 7883, DSSTox_RID_77158, DSSTox_GSID_23712, 2,4-Diamino-5-[3,4,5-trimethoxy-benzyl]pyrimidine, W-104441, 2,4-Diamino-5-(3',4',5'-trimethoxybenzyl)pyrimidine, SR-01000075652, ResprimForte, 5-{[3,4,5-tris(methyloxy)phenyl]methyl}pyrimidine-2,4-diamine, B-Lock, Trimethoprim,(S), Monotrim (TN), Prestwick_485, Triprim (TN), Trimethoprim (TMP), Bactrim (Salt/Mix), Spectrum_000167, Tocris-0650, Trimethoprim [USAN:USP:INN:BAN:JAN], 2w9h, 3fl9, 3n0h, 3s3v, 4km2, AC1L1KNQ, Opera_ID_1760, Prestwick0_000208, Prestwick1_000208, Prestwick2_000208, Prestwick3_000208, Spectrum2_000937, Spectrum3_000643, Spectrum4_000372, Spectrum5_001559, Lopac-T-7883, D0AO5H, Epitope ID:119684, UPCMLD-DP132, AC1Q48DF, Trimethoprim & VRC3375, Lopac0_001271, Oprea1_495058, SCHEMBL24506, BSPBio_000195, BSPBio_002245, KBioGR_000863, KBioSS_000647, 5-25-13-00429 (Beilstein Handbook Reference), KSC492O7H, MLS001201740, MLS002303068, MLS002548881, ARONIS24118, BIDD:GT0190, DivK1c_000589, SPECTRUM1500595, SPBio_000874, SPBio_002116, BPBio1_000215, DTXSID3023712, UPCMLD-DP132:001, BDBM18069, CTK3J2773, HMS501N11, KBio1_000589, KBio2_000647, KBio2_003215, KBio2_005783, KBio3_001465, BBC/254, BIT0154, Trimethoprim, >=98% (HPLC), MolPort-001-826-685, NINDS_000589, ZX-AFC000683, 2,4,5-trimethoxybenzyl)pyrimidine, HMS1568J17, HMS1921I03, HMS2090D14, HMS2092A10, HMS2095J17, HMS2230L06, HMS3259I11, HMS3263P04, HMS3371O18, HMS3652E03, HMS3712J17, Pharmakon1600-01500595, 2,4,5-trimethoxyphenzyl)pyrimidine, ALBB-028968, BCP12148, HY-B0510, KS-00000KQ6, KS-000046JM, ZINC6627681, ZX-AN079781, ZX-AS004468, Tox21_110291, Tox21_200157, Tox21_501271, ANW-42623, BBL005584, BG0348, CCG-40335, GA3656, KM1575, MFCD00036761, NSC752719, NSC757370, s3129, SBB080617, STK177322, STL455117, AKOS001650069, Tox21_110291_1, AC-8427, AN-5554, API0004694, BW-5672, CS-2718, DB00440, KS-1145, LP01271, LS-1627, MCULE-6670904388, NC00483, NSC-752719, NSC-757370, RTR-023930, IDI1_000589, SMP2_000262, NCGC00016055-01, NCGC00016055-02, NCGC00016055-03, NCGC00016055-04, NCGC00016055-06, NCGC00016055-07, NCGC00016055-08, NCGC00016055-09, NCGC00016055-10, NCGC00016055-11, NCGC00016055-12, NCGC00016055-13, NCGC00016055-14, NCGC00016055-16, NCGC00016055-17, NCGC00024707-01, NCGC00024707-03, NCGC00024707-04, NCGC00024707-05, NCGC00024707-06, NCGC00024707-07, NCGC00024707-08, NCGC00257711-01, NCGC00261956-01, AJ-56436, AK154007, CC-35383, CJ-13031, CPD000035999, H148, SAM002264649, SC-15159, ST024737, Trimethoprim/sulfamethoxazole (commercial), SBI-0051237.P003, AB0007348, AB1004879, KB-195701, TL8005108, TR-023930, Trimethoprim 100 microg/mL in Acetonitrile, 2, 5-[(3,4,5-trimethoxyphenyl)methyl]-, AB00052118, BB 0258034, EU-0101271, FT-0601630, ST24044174, C01965, D00145, J10046, Trimethoprim, crystallized, >=99.0% (HPLC), WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1, 5-(3,5-Trimethoxybenzyl)-2,4-diaminopyrimidine, AB00052118-30, AB00052118-32, AB00052118_33, AB00052118_34, Trimethoprim, VETRANAL(TM), analytical standard, 738T705, C-18214, Formulated trimethoprim (NSC 106568) in ethanol, 2,4-diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine, 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine, I06-0086, Pyrimidine,4-diamino-5-(3,4,5-trimethoxybenzyl)-, SR-01000075652-1, SR-01000075652-3, SR-01000075652-6, 5-(3,4,5-Trimethoxy-benzyl)-pyrimidine-2,4-diamine, 5-(3,4,5-Trimethoxybenzyl)-2,4-pyrimidinediamine #, BRD-K07208025-001-06-5, SR-01000075652-10, 2-amino-5-(3,4,5-trimethoxybenzyl)-4-pyrimidinylamine, F0914-5266, Trimethoprim, certified reference material, TraceCERT(R), Z1522566629, 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4(1H,3H)-diimine, Trimethoprim, British Pharmacopoeia (BP) Reference Standard, 2,4-DIAMINO-5-(3',4',5'-TRIMETHOXYBENZYL)PYRIMIDIN, Trimethoprim, European Pharmacopoeia (EP) Reference Standard, Trimethoprim, United States Pharmacopeia (USP) Reference Standard, TRIMETHOPRIM (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE); TMP/SMX (MIXTURE)), Trimethoprim for system suitability, European Pharmacopoeia (EP) Reference Standard, Trimethoprim, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 931

InChIKey: IENJPSDBNBGIEL-DKWTVANSSA-N
SMILES: C([C@@H](C(=O)O)N)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11051941
synonyms found at PubChem are:
51887-89-9, 3-Chloro-L-alanine Hydrochloride, (R)-2-Amino-3-chloropropanoic acid hydrochloride, beta-Chloro-L-alanine hydrochloride, H--Chloro-Ala-OH HCl, (R)-2-Amino-3-chloropropionic Acid Hydrochloride, H--Chloro-D-Ala-OH HCl, L-Alanine, 3-chloro-, hydrochloride, C3H7Cl2NO2, C3H6ClNO2.HCl, 3-Chloro-l-alanine HCl, EU-0100270, H-Ala(3-Cl)-OH.HCl, MLS000859900, SCHEMBL1322249, CHEMBL1256132, CTK8B1809, KS-00000XDL, IENJPSDBNBGIEL-DKWTVANSSA-N, MolPort-003-940-864, ANW-31360, beta;-Chloro-L-alanine hydrochloride, AKOS015845895, 3-CHLORO-L-ALANINEHYDROCHLORIDE, AC-8102, AN-8333, LP00270, ACM51887899, NCGC00093728-01, AK140712, KB-70702, SMR000326762, AX8086104, AX8116483, TR-018465, C1612, FT-0773577, ST24035333, W6670, Z5908, C 9033, K-9517, SR-01000075790, (2R)-2-amino-3-chloro-propanoic acid hydrochloride, SR-01000075790-1, I14-45837, beta-Chloro-L-alanine hydrochloride, Alanine aminotransferase inhibitor

ID: 932

InChIKey: IERFAZQCIAZODG-WFAGLZIHSA-N
SMILES: C[C@@]1(CCC[C@]2(C1CCC(=C)C2CC[C@@](C)(C=C)O)C)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708597
synonyms found at PubChem are:
EPI(13)TORULOSOL, Spectrum_000666, SpecPlus_000194, Spectrum2_000319, Spectrum3_001282, Spectrum4_001674, Spectrum5_000061, AC1O8FF0, BSPBio_002883, KBioGR_002227, KBioSS_001146, SPECTRUM300058, DivK1c_006290, SPBio_000318, CHEMBL3039320, KBio1_001234, KBio2_001146, KBio2_003714, KBio2_006282, KBio3_002103, CCG-38595, SDCCGMLS-0066541.P001, NCGC00178409-01, SR-05000002566, SR-05000002566-1, BRD-A21113731-001-02-5, BRD-A21113731-001-03-3, (3S)-5-[(5S,8aR)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-1-en-3-ol

ID: 933

InChIKey: IEVVSJFLBYOUCJ-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C2=C1C(=O)OC3=C(O2)C4=C(C(=C3C)O)C(=O)OC4O)C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5379540
synonyms found at PubChem are:
Norstictic acid, Bryopogonic acid, 571-67-5, 1,3-Dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro(4,5-b)(1,4)benzodioxepin-11-carboxaldehyde, 7H-Isobenzofuro(4,5-b)(1,4)benzodioxepin-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-, KBio3_001409, 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-, Spectrum_000470, Spectrum2_000171, Spectrum3_000235, Spectrum4_001573, Spectrum5_000226, BSPBio_001909, KBioGR_002126, KBioSS_000950, SPECTRUM201716, SPBio_000061, CHEMBL228281, SCHEMBL13287269, KBio2_000950, KBio2_003518, KBio2_006086, IEVVSJFLBYOUCJ-UHFFFAOYSA-N, HMS1923A11, BDBM50442875, CCG-38381, NCGC00095221-01, NCGC00095221-02, NCGC00095221-03, SR-05000002624, SR-05000002624-1, BRD-A80079592-001-02-4, BRD-A80079592-001-03-2, 1,4,10-Trihydroxy-5,8-dimethyl-3,7-dioxo-1,3-dihydro-7H-2,6,12-trioxabenzo[5,6]cyclohepta[1,2-E]indene-11-carbaldehyde #, 1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-3,7-dihydro-1H-benzo[e]isobenzofuro[5,4-b][1,4]dioxepine-11-carbaldehyde

ID: 934

InChIKey: IFIUFCJFLGCQPH-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2921148
synonyms found at PubChem are:
BRL-50481, 433695-36-4, BRL 50481, N,N,2-trimethyl-5-nitrobenzenesulfonamide, UNII-03G869PR3P, BRL50481, Benzenesulfonamide, N,N,2-trimethyl-5-nitro-, 5-Nitro-2,N,N-trimethylbenzenesulfonamide, CHEMBL484928, 03G869PR3P, AC1MFLLI, D00MBG, Cambridge id 6971444, GTPL5154, SCHEMBL4073001, CHEBI:93472, CTK1D2710, DTXSID30195832, IFIUFCJFLGCQPH-UHFFFAOYSA-N, MolPort-000-628-169, HMS3260P09, HMS3268D16, ZINC4844756, Tox21_500234, BDBM50277784, BS0220, MFCD03039912, STL377005, AKOS001298159, CCG-221538, LP00234, MCULE-4651516113, TRA0099262, NCGC00092345-01, NCGC00092345-02, NCGC00092345-03, NCGC00092345-04, NCGC00092345-05, NCGC00092345-06, NCGC00092345-07, NCGC00260919-01, BC6218998, HY-109586, N,N,2-Trimethyl-5-nitro-benzenesulfonamide, RT-011818, CS-0032567, EU-0100234, FT-0663604, ST50778990, BRL 50481, >=98% (HPLC), solid, N,N,2-trimethyl-5-nitrobenzene-1-sulfonamide, 2-methyl-5-nitro(N,N-dimethyl)benzenesulfonamide, dimethyl[(2-methyl-5-nitrophenyl)sulfonyl]amine, SR-01000247780, SR-01000247780-1, BRD-K84266862-001-01-6, BRD-K84266862-001-02-4, F1084-0159, 3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene, 5-Nitro-2-N,N-trimethylbenzenesulfonamide

ID: 935

InChIKey: IGFHQQFPSIBGKE-UHFFFAOYSA-N
SMILES: CCCCCCCCCC1=CC=C(C=C1)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1752
synonyms found at PubChem are:
4-nonylphenol, 4-n-Nonylphenol, p-Nonylphenol, 104-40-5, Phenol, 4-nonyl-, para-Nonylphenol, p-n-Nonylphenol, Phenol, nonyl-, Phenol, p-nonyl-, Nonylphenol (mixed), Phenol, nonyl derivs., 4-nonyl phenol, para Nonyl phenol, p -n -Nonylphenol, p-nonyl phenol, 4-Nonyl-Phenol, 4-n-Nonyl phenol, CCRIS 1251, HSDB 5359, EINECS 203-199-4, BRN 2047450, CHEBI:34440, IGFHQQFPSIBGKE-UHFFFAOYSA-N, P-NONYLPHENOL (ENDOCRINE DISRUPTER), DSSTox_CID_1857, DSSTox_RID_79098, DSSTox_GSID_33836, 68081-86-7, 4-NP, MFCD00002396, CAS-104-40-5, C9-Alkylated phenol, (C9)Alkylated phenol, UNII-I03GBV4WEL, nonyl-phenol, p-nonyl-phenol, Para-nonyl phenol, EINECS 268-359-8, Spectrum_001973, SpecPlus_000624, AC1Q2VYR, Spectrum2_001832, Spectrum3_000872, Spectrum4_000712, Spectrum5_002066, 4-n-Nonylphenol, 85%, 4-n-Nonylphenol, 98%, I03GBV4WEL, 1-(4-Hydroxyphenyl)nonane, AC1L1C5R, AC1Q7A7Y, BIDD:PXR0002, SCHEMBL15887, BSPBio_002543, KBioGR_001263, KBioSS_002539, SPECTRUM330085, 3-06-00-02067 (Beilstein Handbook Reference), KSC180Q2T, BIDD:ER0006, DivK1c_006720, SPBio_001903, CHEMBL153062, DTXSID5033836, CTK0I0829, KBio1_001664, KBio2_002530, KBio2_005098, KBio2_007666, KBio3_002043, MolPort-001-792-012, 4-Nonylphenol, analytical standard, ZINC1850497, Tox21_201241, Tox21_303647, BDBM50410532, CCG-39613, LMPK15010001, LS-375, SBB059316, STL453644, AKOS015888197, MCULE-5930378829, RTR-000982, TRA0078987, NCGC00090918-01, NCGC00090918-02, NCGC00090918-03, NCGC00090918-05, NCGC00090918-06, NCGC00090918-07, NCGC00090918-08, NCGC00257420-01, NCGC00258793-01, AN-24676, CC-20192, KB-193654, TL8000182, TR-000982, FT-0619310, ST50827096, 4-n-Nonylphenol 10 microg/mL in Acetonitrile, 4-n-Nonylphenol 10 microg/mL in Cyclohexane, 4-n-Nonylphenol 100 microg/mL in Cyclohexane, C14550, 4-Nonylphenol, PESTANAL(R), analytical standard, C-33468, SR-05000002459, J-001167, SR-05000002459-1, I01-10138, I14-50858, 4-Nonylphenol, certified reference material, TraceCERT(R), 29832-11-9

ID: 936

InChIKey: IGJQUJNPMOYEJY-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC=CN1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 14079
synonyms found at PubChem are:
2-ACETYLPYRROLE, 1072-83-9, 1-(1H-Pyrrol-2-yl)ethanone, 1-(1H-Pyrrol-2-yl)ethan-1-one, 2-acetyl pyrrole, 2-Pyrrolylethanone, 2-Acetyl-1H-pyrrole, Methyl pyrrol-2-yl ketone, Ethanone, 1-(1H-pyrrol-2-yl)-, 2-Pyrrolyl methyl ketone, Ketone, methyl pyrrol-2-yl, 1-(2-Pyrrolyl)-1-ethanone, Methyl 2-pyrrolyl ketone, 1-(1h-pyrrol-2-yl)-ethanone, PYRROLE-B-METHYL KETONE, 1-(1H-pyrrole-2-yl)-ethanone, 1-(1H-pyrrol-2-yl)1-ethanone, Pyrrole-alpha-methyl ketone, UNII-9K28W7PM6N, Pyrrole, 2-acetyl, FEMA No. 3202, CCRIS 6778, CHEBI:59981, Methyl 2-pyrryl ketone, 1H-Pyrrole, 2-acetyl, EINECS 214-016-2, NSC 42861, BRN 0001882, 9K28W7PM6N, IGJQUJNPMOYEJY-UHFFFAOYSA-N, 2-Acetopyrrole, 2-acetyl-pyrrole, Pseudoacetylpyrrole, acetylpyrrole, 2-, PubChem20915, methyl-2-pyrrolyl ketone, Spectrum2_001956, Spectrum3_001993, Pyrryl-alpha-methyl ketone, Epitope ID:136036, ACMC-1C1H0, DSSTox_CID_27084, DSSTox_RID_82096, DSSTox_GSID_47084, BSPBio_003593, SPECTRUM240422, 5-21-07-00204 (Beilstein Handbook Reference), KSC491I9B, Pyrrole-.alpha.-methyl ketone, SCHEMBL150349, SPBio_002051, AC1L232Z, SCHEMBL8153085, CHEMBL1414126, DTXSID0047084, CTK3J1490, FEMA 3202, KBio3_003031, KS-00000MRH, MolPort-000-141-759, 1-(1H-Pyrrol-2-yl)ethanone #, ZINC153027, NSC42861, 2-Acetylpyrrole, analytical standard, Ethanone, 1-(1H-pyrrole-2-yl)-, Tox21_300952, ANW-15507, BBL010104, CCG-39485, MFCD00005220, NSC-42861, SBB066752, STK801458, 1-(1H-Pyrrol-2-yl)ethanone, 9CI, AKOS000120308, AM90575, BS-3734, CS-W013672, MCULE-8111376055, RP00471, RTC-020271, SDCCGMLS-0066967.P001, TRA0079648, 2-Acetylpyrrole, ReagentPlus(R), 99%, Methyl 2-pyrrolyl ketone, >=98%, FG, NCGC00095914-01, NCGC00095914-02, NCGC00095914-03, NCGC00254854-01, 1-(1H-Pyrrol-2-yl)ethan-1-one, tech, AJ-12875, AN-19674, CJ-01218, KB-08031, L153, LS-87323, SC-25927, ZB005320, CAS-1072-83-9, AB1001979, ST2414914, TC-020271, 1-(1H-pyrrol-2-yl)ethanone (acetylpyrrole), A0894, FT-0610982, 72A839, K-0562, 2-Acetylpyrrole, Vetec(TM) reagent grade, 98%, AI-942/25034253, SR-05000002372, I11-0039, Q-200225, SR-05000002372-1, Z56899162, F8889-9291, InChI=1/C6H7NO/c1-5(8)6-3-2-4-7-6/h2-4,7H,1H

ID: 937

InChIKey: IGRYPUQJEDJLHC-UHFFFAOYSA-N
SMILES: CN1C=CC2=C1C=CC(=C2)NC(=O)NC3=CN=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5311422
synonyms found at PubChem are:
SB 200646 hydrochloride, 143797-62-0, SB-200646 hydrochloride, SB-200646A, SB200646, AC1NSKLO, CHEMBL536255, SCHEMBL2116886, CTK8F0080, MolPort-023-276-082, AKOS024456555, ACM143797620, KB-303005, RT-015637, B5104, SR-01000597751, SR-01000597751-1, 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea hydrochloride

ID: 938

InChIKey: IGULCCCBGBDZKQ-UHFFFAOYSA-M
SMILES: C1CC2C(C1)C3CC2CC3OC(=S)[S-].[K+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 2733485
synonyms found at PubChem are:
D609, D-609 potassium, 83373-60-8, D609, Potassium Salt, D-609, Tricyclodecan-9-yl-xanthogenate, K, CHEMBL404954, O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate Potassium salt, tricyclodecane-9-yl-xanthogenate, D 609, EINECS 280-379-9, O-(Octahydro-4,7-methano-1H-inden-5-yl) carbonopotassium dithioate, Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester potassium, AC1N6FW5, IGULCCCBGBDZKQ-UHFFFAOYSA-M, MolPort-003-983-753, MolPort-023-276-099, MolPort-039-145-091, HMS1362A05, HMS3263J06, HMS3267J20, HMS3403A05, Tox21_501242, Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate, AKOS024456596, AKOS025147303, O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonodithioate potassium salt, CCG-207969, CCG-222546, CS-0078, LP01242, TRICYCLODECAN-9-YL XANTHOGENATE, NCGC00016205-02, NCGC00025162-02, NCGC00094483-01, NCGC00261927-01, HY-70072, KB-76392, EU-0101242, T 8543, SR-01000597564, SR-01000597564-1, (Tricyclo[5.2.1.0~2,6~]Dec-8-Yloxy)Carbonothioylsulfide, O-tricyclo[5.2.1.02,6] dec-9-yl dithiocarbonate potassium salt, (potassiosulfanyl)({tricyclo[5.2.1.0^{2,6}]decan-8-yloxy})methanethione

ID: 939

InChIKey: IGYRPDIWSYGHMY-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(C(=O)N(C1)CC2=CC=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 54677973
synonyms found at PubChem are:
EBPC, 4450-98-0, Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester, 1-benzyl-4-[ethoxy(hydroxy)methylidene]pyrrolidine-2,3-dione, ethyl 1-benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate, AB-337/40897020, 1-Ebpc, ETHYL 1-BENZYL-3-HYDROXY- 2-OXO[5H]PYRROLE-4-CARBOXYLATE, SMR000567214, NSC229530, NSC 229530, AC1NWUZJ, Spectrum_001772, SpecPlus_000694, AC1NUNK9, Maybridge1_001985, Spectrum2_001831, Spectrum3_001013, Spectrum4_001141, Spectrum5_001668, UNII-MW8LQ9P85C, AC1L40XY, AC1Q6DC1, MW8LQ9P85C, Oprea1_462688, BSPBio_002765, KBioGR_001681, KBioSS_002253, MLS001181500, MLS006012020, DivK1c_006790, SPBio_001901, SCHEMBL4755307, CTK8D6833, CTK8E3208, HMS547C05, KBio1_001734, KBio2_002252, KBio2_004820, KBio2_007388, KBio3_001985, AOB5093, DTXSID50196205, IGYRPDIWSYGHMY-UHFFFAOYSA-N, MolPort-002-892-938, HMS2867I16, HMS3263P19, HMS3266I08, EBPC, >=98% (HPLC), ZINC5853925, ZX-RL004530, Tox21_501199, 3779AE, BN0202, CCG-39612, MFCD00179167, AKOS015838809, AS-5259, NSC-229530, TRA0038916, NCGC00024631-01, NCGC00024631-02, NCGC00261884-01, AJ-55065, CP-10668, KB-111607, TR-017104, B6333, FT-0667819, SR-01000597709, I04-4054, SR-01000597709-1, ethyl 1-benzyl-4-hydroxy-5-oxo-2H-pyrrole-3-carboxylate, 1-benzyl-3-hydroxy-4-ethoxycarbonyl-2,5-dihydro-2-pyrrolone, (4E)-1-benzyl-4-[ethoxy(hydroxy)methylidene]pyrrolidine-2,3-dione, (4Z)-1-benzyl-4-[ethoxy(hydroxy)methylidene]pyrrolidine-2,3-dione, 1-Benzyl-2,5-dihydro-4-hydroxy-5-oxo-1H-pyrrole-3-carboxylic acid ethyl ester, 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-, ethyl ester, 2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-1H-pyrrole-3-carboxylic acid ethyl ester

ID: 940

InChIKey: IHBMYWCPERKOHM-UHFFFAOYSA-N
SMILES: CC1=C(OC2=CC=CC=C2C1=O)C3=CC=C(C=C3)[N+](=O)[O-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 2121642
synonyms found at PubChem are:
4'-Nitro-3-methylflavone, AC1M2P3X, CHEMBL2235760, MolPort-004-050-077, ZINC2657894, MCULE-6644468652, 3-methyl-2-(4-nitrophenyl)chromen-4-one, 3-methyl-2-(4-nitrophenyl)-4H-chromen-4-one, Z57008975, 775315-33-8

ID: 941

InChIKey: IHCDKJZZFOUARO-UHFFFAOYSA-M
SMILES: CC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5282389
synonyms found at PubChem are:
6209-17-2, Sulfacetamide sodium monohydrate, Sodium sulfacetamide, Sulfacetamide sodium salt hydrate, Sulfacetamide sodic hydrate, UNII-4NRT660KJQ, Sulfacetamide sodium [USP], Cetamide, Sulfair Forte, Sulfair 10, 4NRT660KJQ, Sulamyd sodium monohydrate, CHEBI:63858, OCUSULF-30, BLEPH-30, Sulfacetamide sodium salt monohydrate, Sulphacetamide sodium, Klaron (TN), sulfacetamide sodium hydrate, Sulfacetamide sodium (USP), Sodium N-sulfanilylacetamide monohydrate, N1-Acetylsulfanilamide sodium monohydrate, Sulfacetamide sodium salt, N-[(4-aminophenyl)sulfonyl]acetamide, oxamethane, sodium salt, Acetamide, N-[(4-aminophenyl)sulfonyl]-, monosodium salt, monohydrate, Acetamide, N-sulfanilyl-, monosodium salt, monohydrate, N-(p-Aminobenzenesulfonyl)acetamide, sodium;acetyl-(4-aminophenyl)sulfonylazanide;hydrate, N-(4-Aminophenylsulfonyl)acetamide sodium salt, Ocusulf, Plexion, Prascion, Rosaderm, Sulfacel, Sulfatol, Sumaxin, Topisulf, Cerisa, Claris, Rosula, Bleph, N-Sulfanilylacetamide monosodium salt monohydrate, Zencia wash, Acetamide, N-((4-aminophenyl)sulfonyl)-, monosodium salt, monohydrate, Cetamide (TN), Prestwick_427, Bleph (TN), AC1O4WGX, C8H9N2NaSO3.H2O, MLS002154172, CHEMBL1723241, KS-00004DFG, DTXSID50211129, MolPort-002-136-723, MolPort-002-931-938, MolPort-003-896-550, HMS1568C09, HMS2095C09, HMS2231L18, HMS3372D13, HMS3712C09, 8069AF, GA4107, MFCD00007885, s4750, SBB012461, STK023979, AKOS000489082, AKOS005379705, S4750 Sulfacetamide sodium salt hydr, AN-8784, API0019075, CCG-220014, NCGC00017061-01, NCGC00017061-02, SMR001233470, ST040724, ST069345, CAS-6209-17-2, D00871, sodium acetyl(4-aminophenylsulfonyl)amide hydrate, SR-01000842154, Sodium acetyl((4-aminophenyl)sulfonyl)amide hydrate, sodium acetyl-(4-aminophenyl)sulfonylazanide hydrate, SR-01000842154-2, potassium acetyl(4-aminobenzenesulfonyl)azanide hydrate, sodium acetyl-(4-aminophenyl)sulfonyl-azanide hydrate, sodium acetyl[(4-aminophenyl)sulfonyl]azanide hydrate, sodium acetyl[(4-aminophenyl)sulfonyl]azanide--water (1/1), Sulfacetamide sodium salt monohydrate, >=98.0% (dried material, T), Sulfacetamide sodium, United States Pharmacopeia (USP) Reference Standard

ID: 942

InChIKey: IHGXYCGFTVMJQC-XNTDXEJSSA-N
SMILES: CCOC(=O)C/C(=N/NC(=O)NC1=CC=CC=C1)/C

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 9611398
synonyms found at PubChem are:
ethyl 3-[(anilinocarbonyl)hydrazono]butanoate, MLS000702358, ARONIS019401, CHEMBL3194047, MolPort-001-023-914, MolPort-009-658-029, STK051697, AKOS000486567, SMR000228653, BB0274322, AN-329/40239167, ethyl (3E)-3-[2-(phenylcarbamoyl)hydrazinylidene]butanoate

ID: 943

InChIKey: IHLAQQPQKRMGSS-UHFFFAOYSA-N
SMILES: C1C(CN(C1=O)CC(=O)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4626
synonyms found at PubChem are:
oxiracetam, 62613-82-5, 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide, 4-Hydroxy-2-oxopyrrolidine-N-acetamide, Hydroxypiracetam, Neuromet, ISF 2522, Neuractiv, 4-Hydroxypiracetam, (+-)-Oxiracetam, ISF-2522, 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-, CT-848, 4-Hydroxy-2-oxo-1-pyrrolidineacetamide, CGP 21690E, Oxiracetamum [INN-Latin], CCRIS 4221, Oxiracetam(Random Configuration), UNII-P7U817352G, CGP-21690E, BRN 1529719, C6H10N2O3, GNF-PF-1005, (+-)-4-Hydroxy-2-oxo-1-pyrrolidineacetamide, 1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-, (+-)-, P7U817352G, NCGC00015768-02, 2-(4-HYDROXY-2-OXO-1-PYRROLIDINYL)ACETAMIDE, Oxiracetamum, Oxiracetam [BAN:INN], Oxiracetam [INN:BAN], oxiractam, Neupan, Oriest, Senex, Oxiracetam (INN), D0Z4BV, AC1L1IL7, DSSTox_CID_25180, DSSTox_RID_80728, DSSTox_GSID_45180, Lopac0_000933, CHEMBL36633, SCHEMBL526050, DTXSID9045180, 4-Hydroxypyrrolidone-2-acetamide, CTK7D3261, CHEBI:134788, IHLAQQPQKRMGSS-UHFFFAOYSA-N, MolPort-003-904-263, HMS3262L08, HMS3652J06, ACT04730, BCP06209, HY-B1715, Tox21_110218, Tox21_500933, AC-670, AN-929, CGP 21690, CO0043, CT 848, MFCD00242951, RW2749, s4270, AKOS013252523, AB05478, ACN-001375, CCG-205014, CS-8012, LP00933, MCULE-8223030209, RP17379, TRA0048419, KS-00000O50, 4- Hydroxy-2-oxopyrrolidine-N-acetamide, 4-hydroxypyrrolidin-2-on-1-yl acetamide, NCGC00015768-03, NCGC00015768-04, NCGC00094242-01, NCGC00094242-02, NCGC00261618-01, 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide, 68567-97-5, AS-11801, BC214744, SC-46880, AB0010774, AB1004891, CAS-62613-82-5, KB-309910, LS-137061, LS-137065, EU-0100933, FT-0630731, O0398, ST24035884, ST24039452, 2-(4-hydroxypyrrolidin-2-on-1-yl) acetamide, EN300-75437, 2-(4-hydroxy-2-oxo-pyrrolidin-1-yl)acetamide, A21970, D07346, M-3053, O 3011, 613O825, SR-01000076046, I06-0094, Q-201526, SR-01000076046-1, Z1259086528

ID: 944

InChIKey: IHVRWFJGOIWMGC-NSCUHMNNSA-N
SMILES: COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6255462
synonyms found at PubChem are:
33626-08-3, (E)-5-(4-Methoxystyryl)benzene-1,3-diol, 4'-Methoxyresveratrol, Desoxyrhapontigenin, RESVERATROL 4'-METHYL ETHER, CHEMBL291501, 1,3-Benzenediol, 5-[(1E)-2-(4-methoxyphenyl)ethenyl]-, Spectrum5_000570, BSPBio_003527, SCHEMBL563261, SCHEMBL563262, 4'-Methoxystilbene-3,5-diol, AC1O2O02, 4/'-Methoxystilbene-3,5-diol, BML 233, BML-233, CHEBI:108593, IHVRWFJGOIWMGC-NSCUHMNNSA-N, MolPort-003-666-051, 3,5-dihydroxy-4''-methoxystilbene, ZINC3978779, 3942AB, BDBM50085541, CCG-38350, 5-(4-methoxystyryl)benzene-1,3-diol, AKOS015915073, AC-7025, SDCCGMLS-0066773.P001, QTL1_000070, (E)-3,5-dihydroxy-4''-methoxystilbene, 13E-3,5-dihydroxy-4''-methoxystilbene, NCGC00094628-01, NCGC00094628-02, 3,5-dihydroxy-4'-methoxy-trans-stilbene, AJ-47573, AT-18606, BR-72821, DS-15252, trans-3,5-dihydroxy-4''-methoxystilbene, ST2402522, 4CH-018067, 626M083, SR-05000002490, 5-[2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol, I14-6894, SR-05000002490-1, 5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene-1,3-diol, 5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol, BRD-K02671211-001-02-2, BRD-K02671211-001-03-0, E 5-[2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol, 5-[(E)-2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol, 5-[2-((E)-4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol

ID: 945

InChIKey: IIBYAHWJQTYFKB-UHFFFAOYSA-N
SMILES: CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 39042
synonyms found at PubChem are:
bezafibrate, 41859-67-0, Bezalip, Cedur, Bezafibrat, Befizal, Bezafibrato, Bezafibratum, Sklerofibrat, Azufibrat, Bezatol, Difaterol, durabezur, Bezabeta, Bezamerck, Reducterol, Bezacur, Eulitop, Solibay, Lipox, Bezafibrat PB, Bezafibratum [INN-Latin], Beza-Lande, Beza-Puren, Regadrin B, Bezafibrato [INN-Spanish], Bezafibrato [Spanish], Bezalip Retard, Bezatol SR (TN), LO 44, Bezatol SR, BM-15.075, BF-759, UNII-Y9449Q51XH, CCRIS 9085, BM 15075, BM 15.075, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid, Bezafibrate [USAN:BAN:INN:JAN], EINECS 255-567-9, 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid, 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid, BRN 4267656, C19H20ClNO4, MLS000028533, CHEMBL264374, CHEBI:47612, IIBYAHWJQTYFKB-UHFFFAOYSA-N, Y9449Q51XH, Propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-, 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid, NCGC00016850-01, BM-15075, SMR000058298, CAS-41859-67-0, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid, DSSTox_CID_9869, Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-, DSSTox_RID_78826, DSSTox_GSID_29869, W-106291, a-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid, Befibrat, Bezafisal, 2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoic acid, 2-[4-(2-[4-Chlorobenzamido]ethyl)-phenoxy]-2-methylpropanoic acid, Beza Lande, Beza Puren, 2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid, 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid, Propionic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-, SR-01000000106, benzofibrate, BezaLande, BezaPuren, 2-{4-[2-(4-chlorobenzamido)ethyl]phenoxy}-2-methylpropanoic acid, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, Bezalip SR, PB, Bezafibrat, Bezafibrate,(S), 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid, Bezafibrate [USAN:INN:BAN:JAN], PEM, Prestwick_724, Bezalip (TN), BENAFIBRATE, BENZHABEITE, PubChem4066, Bezafibrate TAD Brand, Bezafibrate Isis Brand, Bezafibrate Teva Brand, Bezafibrate Bayer Brand, Bezafibrate Elfar Brand, Bezafibrate Hexal Brand, Bezafibrate Roche Brand, Spectrum_001443, BM15.075, Opera_ID_376, Bezafibrate Hennig Brand, Bezafibrate Merckle Brand, Prestwick0_000378, Prestwick1_000378, Prestwick2_000378, Prestwick3_000378, Spectrum2_000922, Spectrum3_001500, Spectrum4_000325, Spectrum5_001079, Spectrum5_001967, TAD Brand of Bezafibrate, Isis Brand of Bezafibrate, Teva Brand of Bezafibrate, Bezafibrate Lakeside Brand, Bayer Brand of Bezafibrate, Bezafibrate Azupharma Brand, Bezafibrate Betapharm Brand, D00WCX, Elfar Brand of Bezafibrate, Hexal Brand of Bezafibrate, Roche Brand of Bezafibrate, AC1L20XS, AC1Q5E4V, Hennig Brand of Bezafibrate, Bezafibrate Cryopharma Brand, Bezafibrate Synthelabo Brand, Merckle Brand of Bezafibrate, SCHEMBL16299, BSPBio_000535, BSPBio_001314, BSPBio_003119, KBioGR_000034, KBioGR_000669, KBioSS_000034, KBioSS_001923, Lakeside Brand of Bezafibrate, MLS001148205, Bezafibrate, >=98%, solid, DivK1c_000092, SPECTRUM1502046, Azupharma Brand of Bezafibrate, Betapharm Brand of Bezafibrate, SPBio_000824, SPBio_002456, Bezafibrate Berlin-Chemie Brand, BPBio1_000589, Cryopharma Brand of Bezafibrate, GTPL2668, Synthelabo Brand of Bezafibrate, DTXSID3029869, BDBM28701, Bezafibrate (JP15/USAN/INN), Bezafibrate (JP17/USAN/INN), CTK8B3343, HMS500E14, KBio1_000092, KBio2_000034, KBio2_001923, KBio2_002602, KBio2_004491, KBio2_005170, KBio2_007059, KBio3_000067, KBio3_000068, KBio3_002619, MolPort-001-738-424, NINDS_000092, Bio2_000034, Bio2_000514, HMS1361B16, HMS1569K17, HMS1791B16, HMS1921H16, HMS1989B16, HMS2089F04, HMS2092B12, HMS2096K17, HMS2233E22, HMS3261D21, HMS3369B13, HMS3402B16, HMS3650K22, HMS3652M22, HMS3713K17, Pharmakon1600-01502046, Berlin Chemie Brand of Bezafibrate, Berlin-Chemie Brand of Bezafibrate, BCP03700, HY-B0637, ZINC3956919, Tox21_110645, Tox21_301845, Tox21_500500, ANW-42342, BG0107, CCG-39683, MFCD00078970, NSC758174, s4159, AKOS005107743, Tox21_110645_1, AB03023, AC-6817, AN-9653, API0001705, BCP9000398, CS-2874, DB01393, HS-0040, LP00500, MCULE-9775992840, NSC-758174, VA10400, Boehringer Mannheim Brand of Bezafibrate, IDI1_000092, IDI1_033784, NCGC00016850-02, NCGC00016850-03, NCGC00016850-04, NCGC00016850-05, NCGC00016850-06, NCGC00016850-07, NCGC00016850-08, NCGC00016850-09, NCGC00016850-10, NCGC00016850-11, NCGC00016850-12, NCGC00016850-15, NCGC00023317-03, NCGC00023317-04, NCGC00023317-05, NCGC00023317-06, NCGC00023317-07, NCGC00023317-08, NCGC00255376-01, NCGC00261185-01, 4CA-0271, Bezafibrate, analytical reference material, SC-04393, BCP0726000153, SBI-0051715.P002, AB1004588, AX8116634, LS-124535, TR-016482, 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy), AB00052265, B3346, FT-0622617, ST51014927, D01366, K-8763, AB00052265-15, AB00052265_16, AB00052265_17, 859B670, I06-1311, SR-01000000106-3, SR-01000000106-4, SR-01000000106-5, BRD-K46018455-001-06-0, BRD-K46018455-001-17-7, SR-01000000106-10, Bezafibrate, European Pharmacopoeia (EP) Reference Standard, 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-M, 2-(4-(2-parachlorobenzamidoethyl)phenoxy)-2-methylpropionic acid, 2-[4-(2-[4-Chlorobenzamido]ethyl)- phenoxy]-2-methylpropanoic acid, 2-[4-[2-(4-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl propanoic acid, 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID, 2-(4-{2-[(4-chlorophenyl)carbonylamino]ethyl}phenoxy)-2-methylpropanoic acid, BF; 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl propanoic acid

ID: 946

InChIKey: IIHSMXMTENPGDE-UHFFFAOYSA-N
SMILES: COC(=O)OC1=CC=CC=C1C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 26579
synonyms found at PubChem are:
CARBONIC ACID, METHYL ESTER, ESTER with SALICYLIC ACID, NSC 89730, BRN 2110011, Benzoic acid, 2-((methoxycarbonyl)oxy)-, o-Carboxyphenyl carbonic acid methyl ester, 14216-34-3, 2-((methoxycarbonyl)oxy)benzoic acid, 2-[(methoxycarbonyl)oxy]benzoic acid, Benzoic acid, 2-[(methoxycarbonyl)oxy]-, AC1L1BFU, SCHEMBL47856, BSPBio_002929, SPECTRUM211363, O-(Carbomethoxy)salicylic acid, 2-methoxycarbonyloxybenzoic acid, AC1Q44E8, CHEMBL1530334, Salicylic acid, methyl carbonate, DTXSID50161958, IIHSMXMTENPGDE-UHFFFAOYSA-N, ZINC393976, METHOXYCARBONYLSALICYLIC ACID, NSC89730, NSC-89730, AKOS004905055, MCULE-6193708792, NCGC00095796-01, NCGC00095796-02, LS-52083

ID: 947

InChIKey: IIVBFTNIGYRNQY-YQLZSBIMSA-N
SMILES: CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@H]4C1=CC(=O)CC4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 91668
synonyms found at PubChem are:
Nomegestrol acetate, 58652-20-3, Nomegestrol 17-acetate, TX 066, NOMAC, Lutenyl, Uniplant, TX-066, Lutenyl (TN), UNII-83J78V5W05, EINECS 261-379-8, Nomegestrol acetate [USAN], MLS002154113, 83J78V5W05, ORG 10486-0, ORG-10486-0, 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione, 19-Norpregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-, 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate, 17-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione 17-acetate, Nomegestrol acetate (USAN), 19-Norpregna-4,6-diene-3,20-dione, 17-alpha-hydroxy-6-methyl-, acetate, [(8S,9S,10R,13S,14S,17R)-17-acetyl-6,13-dimethyl-3-oxo-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate, Surplant, Nomegestrone acetate, AC1L3MJM, Prestwick3_001033, D0V2JK, SCHEMBL37517, BSPBio_001245, BPBio1_001370, CHEMBL1476022, 17-acetoxy-6-methyl-19-norpregna-4,6-diene-3,20-dione, DTXSID90207349, CHEBI:135564, NOMEGESTROL ACETATE:17alpha-Acetoxy-6alpha-methyl-19-Nor-Pregn-4,6-dien-3,20-dione, HMS2098O07, HMS2230M23, HMS3715O07, (8S,9S,10R,13S,14S,17R)-17-acetyl-6,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate, BCP08358, ZINC3938628, CN0044, MFCD00941390, AKOS015896563, Nomegestrol acetate, >=98% (HPLC), AC-1119, ACN-043354, AN-6935, CCG-221033, NCGC00179247-01, BC678124, LS-97336, SMR001233420, AB00514012, D08281, 6-Methyl-17.alpha.-acetoxy-6-19-norprogesterone, 652N203, C-21132, SR-01000841206, I06-2402, SR-01000841206-2, W-105372, BRD-K27351809-001-02-0, 17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione, 19-Norpregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-, (17alpha)-17-Acetyl-6-methyl-3-oxoestra-4,6-dien-17-yl acetate, Nomegestrol acetate, European Pharmacopoeia (EP) Reference Standard, 17-alpha-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dioneacetate, (8S,9S,13S,14S,17R)-17-acetyl-6,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

ID: 948

InChIKey: IJYUPBNUPIRQEP-SATBOSKTSA-N
SMILES: C1CC2=CC(=C(C=C2[C@@H]3[C@@H]1NCC4=CC=CC=C34)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11403931
synonyms found at PubChem are:
Dihydrexidine hydrochloride, Dihydrexidine HCl, (+)-Dihydrexidine hydrochloride, 158704-02-0, EU-0100380, SCHEMBL613123, CHEMBL1256832, MolPort-003-941-107, AKOS024458679, HY-101299, CS-0021115, 123039-93-0, D 5814, SR-01000075824, SR-01000597882, SR-01000075824-1, SR-01000597882-1, (+/-)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride, ( inverted question mark)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride

ID: 949

InChIKey: IKFXPERBVFYFMS-DPILJLKXSA-N
SMILES: CC(=O)O[C@H]1C[C@H](C(C2[C@]1(C3CC[C@]4([C@@H](OC(=O)[C@@H]5[C@@]4([C@@]3(C(=O)C2)C)O5)C6=COC=C6)C)C)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708526
synonyms found at PubChem are:
7-DEACETOXY-7-OXOKHIVORIN, SPBio_000313, Spectrum_000532, SpecPlus_000051, Spectrum2_000237, Spectrum3_000016, Spectrum4_001296, Spectrum5_000051, BSPBio_001651, KBioGR_001671, KBioSS_001012, SPECTRUM100048, DivK1c_006147, SCHEMBL13424852, KBio1_001091, KBio2_001012, KBio2_003580, KBio2_006148, KBio3_000751, CCG-39798, SDCCGMLS-0066357.P001, NCGC00179117-01, SR-05000002744, SR-05000002744-1

ID: 950

InChIKey: IKMDFBPHZNJCSN-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281672
synonyms found at PubChem are:
myricetin, 529-44-2, Cannabiscetin, Myricetol, Myricitin, 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one, 3,3',4',5,5',7-Hexahydroxyflavone, 3,5,7,3',4',5'-Hexahydroxyflavone, UNII-76XC01FTOJ, NSC 407290, CCRIS 5838, 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one, EINECS 208-463-2, NSC407290, CHEMBL164, NSC-407290, BRN 0332331, 76XC01FTOJ, 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one, CHEBI:18152, FLAVONE, 3,3',4',5,5',7-HEXAHYDROXY-, MYC, Q-100601, SMR001233193, SR-01000076005, HSDB 7682, 4gqr, Prestwick_342, Spectrum_001501, SpecPlus_000531, AC1NQYV4, Prestwick0_000465, Prestwick1_000465, Prestwick2_000465, Prestwick3_000465, Spectrum4_001272, Spectrum5_000692, Lopac-M-6760, Myricetin (Cannabiscetin), Myricetin from Myrica cerifera leaf and bark, D0T3PW, BIDD:PXR0079, Lopac0_000740, SCHEMBL19302, BSPBio_000570, KBioGR_001884, KBioSS_001981, MLS002153825, MLS006010718, BIDD:ER0142, DivK1c_006627, Myricetin, analytical standard, SPBio_002509, BPBio1_000628, MEGxp0_000357, DTXSID8022400, ACon1_000267, BDBM15236, cid_5281672, KBio1_001571, KBio2_001981, KBio2_004549, KBio2_007117, KS-00000GOF, 2o63, CHEBI: 18152, IKMDFBPHZNJCSN-UHFFFAOYSA-N, MolPort-001-740-532, REGID_for_CID_5281672, HMS1569M12, HMS2096M12, HMS2231L04, HMS3262C22, HMS3656I05, BCP28295, Myricetin, >=96.0% (HPLC), Myricetin, >=96.0%, crystalline, TNP00286, ZINC3874317, Tox21_500740, AN-939, BBL023468, BS0289, CM0160, GL5441, LMPK12110001, MFCD00006827, Myricetin solution, 20 mM in DMSO, s2326, STL284709, 3,7,3',4',5'-Hexahydroxyflavone, AKOS015903103, AC-4533, CCG-204825, CS-6221, DB02375, KS-5268, LP00740, MCULE-6299186219, 3,3',4',5,5',7-hexOH-Flavone, Cannabiscetin solution, 20 mM in DMSO, 3,3 ,4 ,5,5 ,7-Hexahydroxyflavone, Flavone,3',4',5,5',7-hexahydroxy-, NCGC00015697-01, NCGC00015697-02, NCGC00015697-03, NCGC00015697-04, NCGC00015697-05, NCGC00015697-06, NCGC00015697-07, NCGC00015697-08, NCGC00015697-09, NCGC00015697-10, NCGC00015697-11, NCGC00015697-12, NCGC00015697-13, NCGC00094083-01, NCGC00094083-02, NCGC00094083-03, NCGC00094083-04, NCGC00179517-01, NCGC00179517-02, NCGC00261425-01, 4CN-1085, AJ-46397, AK111247, BC201817, CAS-529-44-2, HY-15097, LS-69005, NCI60_003870, ST057235, AB0149714, AX8140581, TR-018746, EU-0100740, FT-0672573, M2131, N1850, ST24041172, C10107, M 6760, M-1214, S00115, 3,3',4',5,5',7-hexahydroxy-(8CI)- flavone, 529M442, A829320, C07E0ED2-ABF6-4BD3-A2B2-A98CAEF20FD1, Myricetin, primary pharmaceutical reference standard, SR-01000076005-1, SR-01000076005-6, BRD-K43149758-001-04-5, I14-19097, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-1-benzopyran-4-one, 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one #, 3,5,7-tris(oxidanyl)-2-[3,4,5-tris(oxidanyl)phenyl]chromen-4-one, 4H-1-Benzopyran-4-one,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, 2-(3,4,5-TRIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one solution, 20 mM in DMSO, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)- (9CI)

ID: 951

InChIKey: IKPNWIGTWUZCKM-JEDNCBNOSA-N
SMILES: CC(=O)O.CN=C(N)NCCC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 135242
synonyms found at PubChem are:
Tilarginine Acetate, 53308-83-1, L-NMMA, L-NMMA acetate, NG-Monomethyl-L-arginine acetate, Nomega-Me-L-Arg, UNII-2FL3530AF2, NG-Me-L-Arg, AcOH, Tilarginine acetate [USAN], 2FL3530AF2, NG-Methyl-L-arginine acetate salt, ANO-1020, L-Ornithine, N5-[imino(methylamino)methyl]-[CAS], N-Omega-monomethyl-L-arginine acetate, N(G)-Methyl-L-arginine acetate, NG-Monomethyl-L-arginine, Monoacetate Salt, ANO 1020, Tilarginine acetate (USAN), DSSTox_CID_25780, DSSTox_RID_81122, DSSTox_GSID_45780, N5-(Imino(methylamino)methyl)-L-ornithine monoacetate, Nomega-Methyl-L-arginine Acetate, L-Ornithine, N5-(imino(methylamino)methyl)-, monoacetate, SMR000449329, CAS-53308-83-1, Nomega-Monomethyl-L-arginine Acetate, Nomega-Methyl-L-arginine acetate salt, NG-Monomethyl-L-arginine acetate salt, NCGC00024780-01, NCGC00024780-04, M1365, N5-(Methylamidino)-L-ornithine acetate salt, M 7033, NCGC00094091-01, AC1Q5SZL, H-Arg(Me)-OH.AcOH, D06OQI, MLS000758278, MLS001401412, MLS002172472, n5-(n-methylcarbamimidoyl)-l-ornithine acetate(1:1), AC1L362E, SCHEMBL1321022, CHEMBL1256175, DTXSID7045780, L-NMMA, Tilarginine, Targinine, IKPNWIGTWUZCKM-JEDNCBNOSA-N, MolPort-003-849-265, HMS2051M15, HMS2235N20, HMS3262E22, acetic acid; delta-N-methylarginine, Tox21_111246, Tox21_113520, Tox21_113578, Tox21_500750, GL3981, HY-18732A, MFCD00069311, AKOS024458640, CCG-100805, CCG-222054, LP00750, NC00055, NCGC00261435-01, CPD000449329, SAM001247049, B6444, CS-0014213, EU-0100750, FT-0672487, X4986, D09018, A822796, SR-01000597858, NG-Methyl-L-arginine acetate salt, >=98% (TLC), SR-01000597858-1, I14-93543, (E)-Nw'-methyl-L-arginine compound with acetic acid (1:1), (2S)-2-Amino-5-((methylcarbamimidoyl)amino)pentanoic acid monoacetate, acetic acid; (2S)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid, (2S)-2-azanyl-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid; ethanoic acid, (S)-2-amino-5-(3-methylguanidino)pentanoic acid compound with acetic acid (1:1), acetic acid; (2S)-2-amino-5-[[amino(methylimino)methyl]amino]pentanoic acid

ID: 952

InChIKey: IKQRPFTXKQQLJF-IAHYZSEUSA-N
SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCN5CCCC5)N(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 54682938
synonyms found at PubChem are:
ROLITETRACYCLINE, 751-97-3, Rolitetraciclina, Rolitetracyclinum, Reverin, Pyrrolidino-methyl-tetracycline, Synterin, N-(Pyrrolidinomethyl)tetracycline, Pirrolidinometil-tetraciclina, N-(1-Pyrrolidinylmethyl)-tetracycline, UNII-GH9IW85221, Prm-TC, Solvocillin, CHEBI:63334, GH9IW85221, Kinteto, Tetracycline, pyrrolidinomethyl-, C27H33N3O8, Synterin (TN), EINECS 212-031-9, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-4,4a,5,5a-tetrahydrotetracene-2-carboxamide, [(4S,6S,12aS,4aS,5aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1, 11-dioxo(4,5,6,12a,4a,5a-hexahydronaphthacen-2-yl)]-N-(pyrrolidinylmethyl)carb oxamide, AAT 4, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-, Rolitetracycline (JAN/USAN/INN), SQ 15659, AC1NQZM8, Rolitetracycline [USAN:USP:INN:BAN:JAN], SCHEMBL155640, AC1O711S, 7681-32-5 (nitrate), CHEMBL1237046, CTK8G2985, 20685-78-3 (mononitrate), HMEYVGGHISAPJR-IAHYZSEUSA-N, HMS2094O15, Pharmakon1600-01505684, SQ 15, (2Z,4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy-(pyrrolidin-1-ylmethylamino)methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione, BCP15881, Rolitetracycline, analytical standard, MFCD00056562, NSC759177, ZINC14880004, AKOS024284365, Tetracycline, N-(pyrrolidinylmethyl)-, CCG-213512, DB01301, NSC-759177, CC-34284, SO-15659, ST075203, SBI-0206901.P001, FT-0603513, X5947, D02282, AB01563105_01, AB01563105_02, C-23090, SR-05000001744, SR-05000001744-1, (2E,4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy-(pyrrolidin-1-ylmethylamino)methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione, (4S,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

ID: 953

InChIKey: ILEDWLMCKZNDJK-UHFFFAOYSA-N
SMILES: C1=CC(=O)OC2=CC(=C(C=C21)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5281416
synonyms found at PubChem are:
Esculetin, 305-01-1, 6,7-DIHYDROXYCOUMARIN, Cichorigenin, Aesculetin, 6,7-Dihydroxy-2H-chromen-2-one, Cichoriin aglucon, Esculatin, Esculetol, Esculin aglucon, Esculin aglycon, Cichoriin aglycon, Asculetine, 2H-1-Benzopyran-2-one, 6,7-dihydroxy-, 6,7-dihydroxychromen-2-one, 6,7-Dihydroxy-2-benzopyrone, 6,7-Dihydroxy-2H-1-benzopyran-2-one, C9H6O4, Coumarin, 6,7-dihydroxy-, UNII-SM2XD6V944, NSC 26428, CCRIS 7065, 6,7-dihydroxy-1-benzopyran-2-one, EINECS 206-161-5, BRN 0152788, MLS000069479, CHEMBL244743, SM2XD6V944, 6,7-bis(oxidanyl)chromen-2-one, CHEBI:490095, NSC26428, SMR000059055, 7H-1-Benzopyran-7-one, 2,6-dihydroxy-, E-3400, E-3401, 2H-1-Benzopyran-2-one, 6,7-dihydroxy- (9CI), 91753-33-2, Esculetol), Aesculetin ,(S), ACMC-20luwt, Cichorigenin|Aesculetin, AC1NQYFH, Spectrum_001166, 6,7-Dihydroxycounmarin, Aesculetin (cichorigenin, 6,7-dihydroxy-coumarin, SpecPlus_000334, Prestwick0_000940, Prestwick1_000940, Prestwick2_000940, Prestwick3_000940, Spectrum2_000586, Spectrum3_000752, Spectrum4_001886, Spectrum5_000512, bmse000986, D0YZ5G, Oprea1_719746, SCHEMBL24641, 6,7-Dihydroxy-2-chromenone, BSPBio_000880, BSPBio_002364, KBioGR_002416, KBioSS_001646, 5-18-03-00202 (Beilstein Handbook Reference), 6,7-Dihydroxycoumarin, 8CI, KSC148K7L, DivK1c_006430, Esculetin, analytical standard, SPECTRUM1500899, SPBio_000432, SPBio_003049, 6,7-Dihydroxycoumarin, 98%, BPBio1_000968, GTPL5180, Jsp005751, DTXSID3075383, BDBM34571, cid_5281416, CTK3G3670, KBio1_001374, KBio2_001646, KBio2_004214, KBio2_006782, KBio3_001584, ZINC57908, BIB6051, ILEDWLMCKZNDJK-UHFFFAOYSA-N, MolPort-000-709-311, ZX-AFC000486, HMS1570L22, HMS1921M14, HMS2097L22, HMS2233G24, HMS3373K09, KUC108669N, AC1Q7980, ALBB-023362, ZX-AN021876, Coumarin, 6,7-dihydroxy- Esculetin, ACM305356, ANW-43483, BN0888, CCG-38509, CD-051, CE0046, MFCD00006874, NSC-26428, s4711, 6,7-Dihydroxy-2H-chromen-2-one #, AKOS000276955, AKOS030559695, EBD2197580, FCH1117729, MCULE-4460039316, RTR-013104, SDCCGMLS-0066669.P001, KS-0000017Z, SMP2_000093, NCGC00016425-01, NCGC00016425-02, NCGC00016425-03, NCGC00016425-04, NCGC00016425-05, NCGC00016425-06, NCGC00094873-01, NCGC00094873-02, 4CN-0872, AC-18400, AJ-09788, AK114506, AN-44203, AS-11863, CAS-305-01-1, CC-22332, CJ-00486, KB-50565, KSC-11-243-1, LS-55161, NCI60_002119, SC-45867, ST079379, ZB002263, AB0010898, AX8020100, DB-014626, TR-013104, AB00489955, E0386, FT-0620854, N1764, ST24044991, 2H-1-BENZOPYRAN-2-ONE,6,7-DIHYDROXY, C09263, J10146, W-2566, 305E011, A820407, C-06350, SR-01000721907, I14-1622, SR-01000721907-2, BRD-K58149231-001-06-9, BRD-K58149231-001-10-1, Esculetin, European Pharmacopoeia (EP) Reference Standard, InChI=1/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11

ID: 954

InChIKey: ILKJAFIWWBXGDU-MOGDOJJUSA-N
SMILES: CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC6(O2)CCCC6

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 443958
synonyms found at PubChem are:
amcinonide, Cyclocort, 51022-69-6, Amcinonidum, Amcinonido, Triamcinolonacetatcyclopentanonid, amcinonida, Amcinonidum [INN-Latin], CL-34699, Amcinonido [INN-Spanish], Cyclocort (TN), Visderm, UNII-423W026MA9, Amciderm, Amcinonide (JAN/USP/INN), Cyclort, MLS000028656, MLS001333715, CHEBI:31199, 423W026MA9, SMR000058920, 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate, Amcinonid, CL 34699, 19alpha-Fluor-11beta,21-dihydroxy-16alpha,17alpha-(tetramethylen)methylendioxy-1,4-pregnadien-3,20-dion 21-acetat, 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone, 21-acetate, C28H35FO7, Amcinonide [USAN:INN:BAN:JAN], EINECS 256-915-2, 16alpha,17alpha-(cyclopentane-1,1-diyldioxy)-9-fluoro-11beta-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, CL 34,699, triamcinolone 16,17-cyclopentylidenedioxy-21-acetate, NCGC00095071-01, (11?,16?)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-(cyclopentylidenebis(oxy))-9-fluoro-11-hydroxy-, (11beta,16alpha)-, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11.beta.,16.alpha.)-, Amcinonide [USAN:USP:INN:BAN:JAN], Opera_ID_1472, D06XHC, AC1L9FH1, SCHEMBL4720, DSSTox_CID_25905, DSSTox_RID_81217, DSSTox_GSID_45905, MLS001146959, MLS002695893, Amcinonide, analytical standard, GTPL7060, CHEMBL1200732, DTXSID6045905, ILKJAFIWWBXGDU-MOGDOJJUSA-N, MolPort-003-940-103, HMS2235K23, HMS3715D11, HY-B1197, ZINC3977777, Tox21_111411, AKOS015961167, CCG-221135, CS-4805, DB00288, AC-13190, SC-81448, CAS-51022-69-6, X1044, D01387, SR-01000003161, SR-01000003161-2, BRD-K13960744-001-09-7, Amcinonide, United States Pharmacopeia (USP) Reference Standard, 2-[(1'S,2'S,4'R,8'S,9'S,11'S,12'R,13'S)-12'-fluoro-11'-hydroxy-9',13'-dimethyl-16'-oxo-5',7'-dioxaspiro[cyclopentane-1,6'-pentacyclo[10.8.0.0;{2,9}.0;{4,8}.0;{13,18}]icosane]-14',17'-dien-8'-yl]-2-oxoethyl acetate

ID: 955

InChIKey: IMLJLCJZQLGHJS-JEKSYDDFSA-N
SMILES: C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 54680691
synonyms found at PubChem are:
Oxytetracycline dihydrate, 6153-64-6, Terramycin, OXTC, Oxytetracyclini dihydras, Hydroxytetrazyklindihydrat, Oxytetracyclinium dihydricum, UNII-X20I9EN955, CCRIS 9079, X20I9EN955, Terramycin (TN), Oxytetracycline base, DSSTox_CID_3412, DSSTox_RID_77015, DSSTox_GSID_23412, (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrate, 79-57-2 (Parent), 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-, dihydrate, C22H24N2O9, 79-57-2 (ANHYDROUS), Neo-oxy 50/50, SR-01000003006, C22H24N2O9.2H2O, (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;dihydrate, Prestwick_630, CAS-6153-64-6, Oxytetracycline [USP:INN:BAN:JAN], Oxytetracycline [USAN:INN:BAN:JAN], Oxytetracycline hydrate, AC1NQZYS, OTC, SCHEMBL2898, CHEMBL1892210, DTXSID4023412, Oxytetracycline (JAN/USP/INN), MolPort-029-886-747, HMS1568N16, HMS2095N16, HMS3712N16, Tox21_111711, Tox21_300679, MFCD00151234, s2052, AKOS025310865, API0009032, CCG-220307, NCGC00091268-03, NCGC00254587-01, 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, dihydrate, (4S,4aR,5S,5aR,6S,12aS)-, Q412, LS-176184, FT-0603687, D00205, 112702-EP2280007A1, 112702-EP2295437A1, 112702-EP2298775A1, SR-01000003006-6, (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione dihydrate, (4S,4aR,5S,5aR,6S,12aS,Z)-2-(amino(hydroxy)methylene)-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione dihydrate

ID: 956

InChIKey: IMPOOMVZVWKSAP-UHFFFAOYSA-N
SMILES: COC1(COC2=CC=CC=C2O1)C3=NCCN3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957683
synonyms found at PubChem are:
RX 821002 hydrochloride, 109544-45-8, 2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE, 2-[2-(2-Methoxy-1,4-benzodioxanyl)]imidazoline hydrochloride, 2-(3-methoxy-2h-1,4-benzodioxin-3-yl)-4,5-dihydro-1h-imidazole,hydrochloride, SR-01000076111, EU-0101053, MLS002172474, SCHEMBL2488166, CHEMBL1256176, CTK8E8706, DTXSID00474702, MolPort-003-959-470, Tox21_501053, MFCD00069343, AKOS024426444, CCG-222357, LP01053, MCULE-1217710263, KS-000001O7, NCGC00094335-01, NCGC00261738-01, SMR000326839, KB-220452, RT-015469, R 9525, J-002302, RX 821002 hydrochloride, solid, >=98% (HPLC), SR-01000076111-2, SR-01000076111-3, 2-[2-(2-Methoxy-1,4-benzodioanyl)]-imidazoline hydrochloride, hydrochloride (2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline)

ID: 957

InChIKey: IMPPSJRGMZYGJW-UHFFFAOYSA-N
SMILES: COC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC4=C(C=C3)OCO4)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 629853
synonyms found at PubChem are:
derrustone, 5,7-Dimethoxy-3',4'-methylenedioxyisoflavone, IMPPSJRGMZYGJW-UHFFFAOYSA-N, 22044-59-3, SPBio_000806, AC1LCGNA, Spectrum2_000763, Spectrum3_001085, Spectrum4_001238, BSPBio_002730, KBioGR_001736, SPECTRUM1401419, CHEMBL252721, SCHEMBL13657435, KBio3_001950, CHEBI:114196, CCG-40152, LMPK12050360, SDCCGMLS-0066865.P001, NCGC00095747-01, NCGC00095747-02, NCGC00178503-01, SR-05000002584, SR-05000002584-1, BRD-K72135530-001-02-7, 3-(1,3-benzodioxol-5-yl)-5,7-dimethoxychromen-4-one, 3-(1,3-Benzodioxol-5-yl)-5,7-dimethoxy-4H-chromen-4-one #, 5,7-Dimethoxy-3-(3,4-methylenedioxyphenyl)-4H-chromen-4-one, 3-(benzo[d][1,3]dioxol-5-yl)-5,7-dimethoxy-4H-chromen-4-one, InChI=1/C18H14O6/c1-20-11-6-15(21-2)17-16(7-11)22-8-12(18(17)19)10-3-4-13-14(5-10)24-9-23-13/h3-8H,9H2,1-2H

ID: 958

InChIKey: IMSSROKUHAOUJS-MJCUULBUSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6291
synonyms found at PubChem are:
mestranol, 72-33-3, Norquen, Devocin, Menophase, Ovastol, Ethynylestradiol 3-methyl ether, Mestranolum, 3-Methoxyethynylestradiol, EE(sub3)ME, delta-MVE, Ethynylestradiol methyl ether, 3-Methylethynylestradiol, EE3ME, Inostral (steroid), Mestranolo [DCIT], 3-O-Methylethynylestradiol, Mestranolo, Compound 33355, Inostral, 3-Methylethynyloestradiol, 3-Methoxyethynyloestradiol, Mestranolum [INN-Latin], 3-Methoxy-17alpha-ethynylestradiol, Caswell No. 547A, Ethinylestradiol 3-methyl ether, Ethinyloestradiol 3-methyl ether, Ethynyloestradiol 3-methyl ether, SC 4725, 17alpha-Ethinyl estradiol 3-methyl ether, 3-Methoxy-17alpha-ethinylestradiol, 17-Ethynylestradiol 3-methyl ether, 3-Methoxy-17alpha-ethinyloestradiol, 3-Methoxy-17alpha-ethynyloestradiol, 17-Ethynyloestradiol 3-methyl ether, 3-Methoxy-17-alpha-ethinylestradiol, 3-Methoxy-17-alpha-ethynylestradiol, UNII-B2V233XGE7, 17alpha-Ethynylestradiol methyl ether, 3-Methoxy-17-alpha-ethinyloestradiol, 3-Methoxy-17-alpha-ethynyloestradiol, component of Ovulen, CCRIS 377, component of Norinyl, component of Norquen, 17-alpha-Ethynyloestradiol methyl ether, 17alpha-Ethinylestradiol 3-methyl ether, 17alpha-Ethynylestradiol 3-methyl ether, 17alpha-Ethynyloestradiol 3-methyl ether, 3-Methoxy-17-ethynyloestradiol-17-beta, Mestranol [Steroidal oestrogens], 17alpha-Ethinyl oestradiol 3-methyl ether, 17-alpha-Ethinyl estradiol 3-methyl ether, HSDB 3588, 17-alpha-Ethinyl oestradiol 3-methyl ether, Mestranol [USAN:INN:BAN:JAN], component of Ortho-Novum, EINECS 200-777-8, NSC 84032, (8R,9S,13S,14S,17R)-17-Ethynyl-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol, EE3-ME, EPA Pesticide Chemical Code 115401, 17beta-Estradiol, 17-ethynyl-, 3-(methyl ether), BRN 2625905, AI3-51798, MLS000028595, 17-Ethynyl-3-methoxy-1,3,5(10)-oestratien-17-beta-ol, B2V233XGE7, CHEBI:6784, 3-Methoxy-17alpha-ethynyl-1,3,5(10)-estratrien-17beta-ol, 3-Methoxy-17alpha-ethynyl-1,3,5(10)-oestratrien-17beta-ol, 17-alpha-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17-beta-ol, 3-Methoxy-17-alpha-ethynyl-1,3,5(10)-estratrien-17-beta-ol, 3-Methoxy-17-alpha-ethynyl-1,3,5(10)-oestratrien-17-beta-ol, 3-Methoxy-17-alpha-19-norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-Methoxy-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-Methoxy-19-nor-17alpha-pregna-1,3,5(10)-trien-20-yn-17-ol, 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, (17alpha)-, (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol, NCGC00093347-02, Estra-1,3,5(10)-trien-17beta-ol, 17-ethynyl-3-methoxy-, SMR000059128, (17beta)-17-ethynyl-3-(methyloxy)estra-1,3,5(10)-trien-17-ol, 17alpha-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, DSSTox_CID_814, Estra-1,3,5(10)-trien-17-beta-ol, 17-alpha-ethynyl-3-methoxy-, (+)-17-alpha-Ethynyl-17-beta-hydroxy-3-methoxy-1,3,5(10)-estratriene, (17-alpha)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol, (+)-17-alpha-Ethynyl-17-beta-hydroxy-3-methoxy-1,3,5(10)-oestratriene, 17-alpha-Ethynyl-3-methoxy-17-beta-hydroxy-delta-1,3,5(10)-estratriene, 17-alpha-Ethynyl-3-methoxy-17-beta-hydroxy-delta-1,3,5(10)-oestratriene, 3,17-beta-Dihydroxy-17-alpha-ethynyl-1,3,5(10)-estratriene-3-methyl ether, DSSTox_RID_75804, DSSTox_GSID_20814, 17-ethynyl-3-methoxyestra-1(10),2,4-trien-17beta-ol, 17-ethynyl-3-methoxyoestra-1(10),2,4-trien-17beta-ol, 3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17beta-ol, .delta.-MVE, 17-alpha-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, 19-Nor-17alpha-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, 17-Ethynyl-3-methoxyestra-1,3,5(10)-trien-17-ol, 8027 C. B., NSC84032, Ethinyl Estradiol 3 Methyl Ether, Ethinyl Estradiol 3-Methyl Ether, CAS-72-33-3, Prestwick_966, Mestranol, 99%, Mestranol [USAN:USP:INN:BAN:JAN], Opera_ID_872, Prestwick0_000846, Prestwick1_000846, Prestwick2_000846, Prestwick3_000846, D0J1ML, AC1L1M7F, SCHEMBL41391, BSPBio_000831, MLS001077321, MLS001424224, ARONIS24415, BIDD:ER0199, SPBio_002752, Mestranol (JP15/USP/INN), Mestranol (JP17/USP/INN), BPBio1_000915, ethynylestradiol-3-methyl ether, GTPL7087, 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol,3-methoxy-, (17a)-, CHEMBL1201151, DTXSID0020814, BBC/579, MolPort-002-507-152, HMS1570J13, HMS2051J22, HMS2097J13, HMS2230L20, HMS3714J13, HY-B0390, ZINC3815424, Tox21_111200, Tox21_301837, ANW-41268, SBB066071, AKOS005267152, Tox21_111200_1, ACN-043356, CCG-101067, CS-2476, DB01357, LS-7485, MCULE-6161762887, NC00317, NCGC00093347-03, NCGC00093347-05, NCGC00179410-01, NCGC00255342-01, AC-13293, H072, 8027 C. B, AB2000526, TR-031729, S2125, Mestranol, VETRANAL(TM), analytical standard, C07618, D00575, 003M689, SR-01000695429, SR-01000695429-4, BRD-K31920458-001-03-8, BRD-K31920458-001-23-6, Mestranol, European Pharmacopoeia (EP) Reference Standard, (17beta)-17-ethynyl-3-methoxyestra-1(10),2,4-trien-17-ol, Alpha.-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-meth, Mestranol, United States Pharmacopeia (USP) Reference Standard, 17.Alpha.-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-meth, (+)-17alpha-Ethynyl-17beta-hydroxy-3-methoxy-1,3,5(10)-estratriene, (+)-17alpha-Ethynyl-17beta-hydroxy-3-methoxy-1,3,5(10)-oestratriene, (+ )-17.alpha.-Ethynyl-17.beta.-hydroxy-3-methoxy-1,3, 5(10)-oestratriene, (+)-17.alpha.-Ethynyl-17.beta.-hydroxy-3-methoxy-1,3, 5(10)-estratriene, (1S,10R,11S,14R,15S)-14-ethynyl-5-methoxy-15-methyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-2(7),3,5-trien-14-ol, (1S,11S,15S,10R,14R)-14-ethynyl-5-methoxy-15-methyltetracyclo[8.7.0.0<2,7>.0<1 1,15>]heptadeca-2(7),3,5-trien-14-ol, (8''S'',9''S'',13''S'',14''S'',17''S'')-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6''H''-cyclopenta[''a'']phenanthren-17-ol, 43085-54-7, 53445-46-8

ID: 959

InChIKey: IMWZZHHPURKASS-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1)OCC2CNC(=O)O2)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 15459
synonyms found at PubChem are:
METAXALONE, 1665-48-1, Skelaxin, Metaxalon, Methaxalonum, Zorane, Methoxolone, 5-((3,5-Dimethylphenoxy)methyl)oxazolidin-2-one, Metazalone, Metazolone, Metaxolone, AHR-438, Metaxalonum [Latin], Metassalone [DCIT], Metaxalonum [INN-Latin], Metassalone, Metaxalona [INN-Spanish], Metaxalonum, Metaxalona, AHR 438, 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]-, 5-(3,5-Xyloloxymethyl)oxazolidin-2-one, Metaxalona [Spanish], CL 39,148, NSC 170959, 2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-, Metaxalone [USAN:INN:BAN], 5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone, HSDB 3236, 5-((3,5-Xylyloxy)methyl)-2-oxazolidinone, 5-[(3,5-Xylyloxy)methyl]-2-oxazolidinone, 5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one, EINECS 216-777-6, 5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one, BRN 0884592, MLS003106749, CHEBI:6797, IMWZZHHPURKASS-UHFFFAOYSA-N, 5-[(3,5-Dimethylphenoxy)methyl]-2-oxazolidinone, 2-Oxazolidinone, 5-((3,5-dimethylphenoxy)methyl)-, NSC170959, 5-(3,5-dimethylphenoxymethyl)-1,3-oxazolidin-2-one, NCGC00095116-01, DSSTox_CID_3269, 2-Oxazolidinone, 5-[(3,5-xylyloxy)methyl]-, 5-(3,5-dimethylphenoxymethyl)-2-oxazolidinone, DSSTox_RID_76949, DSSTox_GSID_23269, CAS-1665-48-1, SR-05000001978, 5-((3,5-Dimethylphenoxy)methyl)-1,3-oxazolidin-2-one, .meta.Xalone, .meta.Zalone, .meta.Zolone, .meta.Xalon, Skelaxin (TN), Spectrum_001741, SpecPlus_000656, AC1Q6MIL, Metaxalone (USAN/INN), Spectrum2_000548, Spectrum3_001666, Spectrum4_000612, Spectrum5_001685, D0S5CH, AC1L25XO, Oprea1_438855, SCHEMBL34908, BSPBio_003451, KBioGR_001164, KBioSS_002221, DivK1c_006752, SPECTRUM1504229, SPBio_000595, GTPL7609, CHEMBL1079604, DTXSID3023269, Metaxalone, >=98% (HPLC), CTK8F0377, KBio1_001696, KBio2_002221, KBio2_004789, KBio2_007357, KBio3_002671, MolPort-003-666-548, HMS1922H07, HMS2093C22, Pharmakon1600-01504229, BCP28377, HY-B0678, KS-00000ZH8, Tox21_111428, WLN: T5MVOTJ D1OR C1 E1, 2-Oxazolidinone,5-xylyloxy)methyl]-, CCG-39592, MFCD00867700, NSC758703, STL450994, STL451511, AKOS009035315, Tox21_111428_1, CS-2910, DB00660, FS-3218, MCULE-3101469866, NSC-170959, NSC-758703, TRA0047745, NCGC00095116-02, NCGC00095116-03, NCGC00095116-05, BC220747, BR-61006, SMR001821638, SBI-0052859.P002, 2-Oxazolidinone,5-dimethylphenoxy)methyl]-, AB0063964, LS-100704, TR-035874, 4CH-009638, AM20060525, FT-0603568, M2578, ST24029254, 5-(3,5-dimethylphenoxy)methyl-2-oxazolidinone, C07934, D00773, S-2010, 5-((3,5-dimethylphenoxy)methyl)-2-oxazolidinon, AB00053284_04, 665M481, A810747, I06-0370, J-010295, SR-05000001978-1, SR-05000001978-3, BRD-A94709349-001-02-6, BRD-A94709349-001-03-4, 5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one #, 5-{[(3,5-dimethylphenyl)oxy]methyl}-1,3-oxazolidin-2-one, 5-[(3,5-dimethylphenoxy)methyl]-4,5-dihydro-1,3-oxazol-2-ol, Metaxalone, United States Pharmacopeia (USP) Reference Standard, 105801-80-7

ID: 960

InChIKey: INBSTAZMSSCMKU-DLYQOUECSA-N
SMILES: CCN(CC)CC(=O)O[C@H]1CC[C@@]2(C3CC[C@@]4([C@H](CC[C@@]4(C3CC[C@@]2(C1)O)O)C5=CC(=O)OC5)C)C=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 45933
synonyms found at PubChem are:
BRN 0069824, 3-Diethylaminoacetyl strophantidin, Strophanthidin-3-diethylaminoacetate, Strophanthidin, 3-diethylaminoacetyl-, Glycine, N,N-diethyl-, ester with strophanthidin, (3-beta,5-beta)-3-((Diethylaminoacetyl)oxy)-5,14-dihydroxy-19-oxocard-20(22)-enolide, Card-20(22)-enolide, 3-((diethylaminoacetyl)oxy)-5,14-dihydroxy-19-oxo-, (3-beta,5-beta)-, AC1L2EYO, 4-18-00-03135 (Beilstein Handbook Reference), LS-52413, [(3S,5S,10S,13R,14S,17R)-10-formyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 2-(diethylamino)acetate

ID: 961

InChIKey: INDUNANCUDNZJY-BMJUORMOSA-N
SMILES: CC(=O)O[C@H]1[C@@H]2CC3C(CC[C@@]4(C3CC(=O)O[C@H]4C5=COC=C5)C)[C@@](C2=O)([C@H](C1(C)C)CC(=O)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708502
synonyms found at PubChem are:
DIHYDROFISSINOLIDE, KBio3_000696, Spectrum_000581, SpecPlus_000002, Spectrum2_000339, Spectrum3_000088, Spectrum4_001375, Spectrum5_000050, BSPBio_001616, KBioGR_001670, KBioSS_001061, DivK1c_006098, SPBio_000377, CHEMBL3039212, SCHEMBL12998466, KBio1_001042, KBio2_001061, KBio2_003629, KBio2_006197, NCGC00179146-01, SR-05000002734, SR-05000002734-1

ID: 962

InChIKey: INGCLXPSKXSYND-BTJKTKAUSA-N
SMILES: CN1CCC(CC1)C2=CNC3=C2C=C(C=C3)O.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 11957480
synonyms found at PubChem are:
BRL 54443 maleate, BRL 54443 maleate salt, 3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol maleate, 1197333-54-2, EU-0100207, D0S2BB, SCHEMBL4799792, CHEMBL1256797, MolPort-003-940-420, BRL 54443 maleate salt, solid, HMS3260J15, Tox21_500207, BN0117, CCG-221511, LP00207, NCGC00093680-01, NCGC00260892-01, B173, B-173, J-004192, SR-01000075573-1, 3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol maleate salt

ID: 963

InChIKey: INOSMXBKABLUIL-DCKDXSSCSA-N
SMILES: CC1=CCC(=C)[C@H]2CC([C@@H]2CC1)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 18502770
synonyms found at PubChem are:
NCGC00178750-01

ID: 964

InChIKey: INQSMEFCAIHTJG-UHFFFAOYSA-N
SMILES: CN1C2=C(C(=O)N(C1=O)C)NC=N2.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 91268
synonyms found at PubChem are:
Theophylline monohydrate, 5967-84-0, Quibron, Quibron Plus, Theo-Sav, Dimethylxanthine, AEROLATE JR, THEOCLEAR-100, UNII-C137DTR5RG, C7H8N4O2.H2O, THEOCLEAR L.A.-260, 1,3-Dimethylxanthine monohydrate, C137DTR5RG, THEOPHYLLINE IN DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE AND DEXTROSE 5% IN PLASTIC CONTAINER, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, monohydrate, THEOPHYLLINE 0.2% AND DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE 0.04% AND DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE 0.08% AND DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE 0.16% AND DEXTROSE 5% IN PLASTIC CONTAINER, THEOPHYLLINE 0.32% AND DEXTROSE 5% IN PLASTIC CONTAINER, Theophylline (USP), THEOBID JR, Theophylline [BAN:JAN], Theophylline [USP:BAN:JAN], Accurbron (TN), Prestwick_1055, ACMC-20ajit, AC1L3LQJ, SCHEMBL387338, CHEMBL1355736, CTK2A2927, KS-00000XPW, DTXSID40208361, MolPort-002-339-588, HMS1570P07, HMS2097P07, HMS3714P07, 7875AF, AKOS015960702, CCG-220873, NCGC00017052-01, AC-12160, SC-66614, CAS-5967-84-0, LS-176020, FT-0694001, ST50411853, D06103, SR-01000075195-6, I14-62379, 1,3-dimethyl-1,3,7-trihydropurine-2,6-dione, hydrate, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, hydrate, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with1,2-ethanediamine (2:1)OTHER CA INDEX NAMES:1,2-Ethanediamine, compd. with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:2), 64790-23-4

ID: 965

InChIKey: INVGWHRKADIJHF-UHFFFAOYSA-N
SMILES: C[N+]1=C2C(=C3C=CC4=C(C3=C1)OCO4)C=CC5=CC6=C(C=C52)OCO6

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5154
synonyms found at PubChem are:
SANGUINARINE, 2447-54-3, Pseudochelerythrine, Sanguinarin, sangvinarin, Veadent, Sanguiritrin, SANGUINARIUM, Dimethylenedioxy benzphenanthridine, UNII-AV9VK043SS, C20H14NO4, EINECS 219-503-3, Benzophenanthridine alkaloid, BRN 3915507, AV9VK043SS, CHEBI:17183, NCGC00015959-03, CAS-2447-54-3, [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-, DSSTox_CID_25204, DSSTox_RID_80748, DSSTox_GSID_45204, Sangrovit, y-Chelerythrine, SR-01000075650, 13-Methyl[1,3]benzodioxolo[5,6-C][1,3]dioxolo[4,5-I]phenanthridin-13-Ium, Spectrum_000259, 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium nitrate, Prestwick0_000987, Prestwick1_000987, Prestwick2_000987, Prestwick3_000987, Spectrum2_000724, Spectrum3_001148, Spectrum4_001838, Spectrum5_000635, Lopac-S-5890, D0T3NB, AC1L1JQ3, cid_5154, C20H14NO4Cl, Lopac0_001108, BSPBio_001053, BSPBio_002675, KBioGR_002542, KBioSS_000739, ZINC706, MLS002154085, DivK1c_000495, Pseudochelerythrine;Sanguinarin, SCHEMBL123241, SPBio_000648, SPBio_002954, BPBio1_001159, CHEMBL417799, 5578-73-4 (chloride), 4752-86-7 (nitrate), DTXSID0045204, SCHEMBL17131945, BDBM25525, KBio1_000495, KBio2_000739, KBio2_003307, KBio2_005875, KBio3_002175, INVGWHRKADIJHF-UHFFFAOYSA-N, MolPort-002-526-863, NINDS_000495, HMS1571E15, HMS2098E15, BCP13614, HY-N0052, Tox21_110268, 4022AH, (1,3)-Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13-methyl-, AKOS025311557, Tox21_110268_1, CCG-205184, CS-3818, SDCCGMLS-0066612.P001, IDI1_000495, NCGC00015959-01, NCGC00015959-02, NCGC00015959-04, NCGC00015959-05, NCGC00015959-09, NCGC00160289-01, NCGC00160289-02, AN-50934, M892, SC-89839, SMR001233394, ZB000158, SBI-0051077.P003, LS-144493, AB00053789, FT-0634289, N1338, C06162, AB00053789_04, 447S543, Q-100313, SR-01000075650-7, BRD-K66898851-001-03-7, 5-Methyl-2,3:7,8-bis(methylenedioxy)benzo[c]phenanthridinium(1+), [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, 13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, (1,3)-Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13-methyl- (9CI), 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium(1+), 9CI, 1265889-92-6, 13-methyl-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium, 18203-15-1, 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0;{2,10}.0;{4,8}.0;{14,22}.0;{17,21}]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaen-24-ium, 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium, 857014-91-6, UI5

ID: 966

InChIKey: INYYVPJSBIVGPH-QHRIQVFBSA-N
SMILES: CN1CC[C@@]23CC(=O)C(=C[C@@H]2[C@@H]1CC4=C3C(=C(C=C4)OC)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5459308
synonyms found at PubChem are:
Sinomenine, 115-53-7, Cucoline, Kukoline, Coculine, Sabianine A, CCRIS 1550, UNII-63LT81K70N, EINECS 204-094-6, BRN 0095280, CHEBI:9163, CHEMBL248095, 63LT81K70N, (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one, 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one, cuculine, 9-alpha,13-alpha,14-alpha-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, SR-05000002170, sinomenine A bismethyliodide, Sinomenine,(S), Sinomenine (Cucoline), Spectrum2_001242, Spectrum3_001134, Spectrum4_001981, Spectrum5_001621, D0F9WF, UPCMLD-DP085, BSPBio_002627, KBioGR_002508, 5-21-13-00516 (Beilstein Handbook Reference), SCHEMBL363812, SPECTRUM1505253, SPBio_001144, NP51, 4-hydroxy-3,7-dimethoxy-17-methylmorphin-7-en- 6-one, UPCMLD-DP085:001, BCBcMAP01_000195, KBio3_002127, INYYVPJSBIVGPH-QHRIQVFBSA-N, MolPort-002-507-299, BDBM224031, ALBB-020908, BCP20032, ZINC1280591, 6080-33-7 (hydrochloride salt), BDBM50241298, CCG-39100, s2359, AKOS000265568, AKOS015960539, AKOS016023715, AC-8025, AN-8438, SMP1_000273, NCGC00161641-01, NCGC00161641-02, NCGC00161641-04, NCGC00161641-05, AJ-25305, AN-24973, BC202689, CC-34432, CC-34433, KB-80597, LS-92117, O600, SC-13744, C09643, 115S537, C-19980, Sinomenine, 0.3 mol chloroform of crystallization, SR-05000002170-2, SR-05000002170-3, BRD-K83459933-001-02-1, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one, (9alpha,13alpha,14alpha)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one, (9alpha,13alpha,14alpha)-4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride, morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9alpha,13alpha,14alpha)-, hydrochloride, SNM

ID: 967

InChIKey: IOIMDJXKIMCMIG-UHFFFAOYSA-N
SMILES: CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5420
synonyms found at PubChem are:
iso-OMPA, tetraisopropyl pyrophosphoramide, 513-00-8, TETRAISOPROPYLPYROPHOSPHAMIDE, Tetraisopropylpyrophosphoramide, MLS002153308, CHEMBL494887, Diphosphoramide, N,N',N'',N'''-tetrakis(1-methylethyl)-, EINECS 208-149-5, Tetra(monoisopropyl)pyrophosphortetramide, N,N',N'',N'''-Tetraisopropyldiphosphoramide, N-[Bis(isopropylamino)phosphoryloxy-(isopropylamino)phosphoryl]propan-2-amine, n,n'-diisopropylphosphorodiamidic anhydride, AC1L1KBH, Lopac-T-1505, D09QDC, Lopac0_001184, Tetraisoproryl Pyrophosphoramide, AC1Q6T49, SCHEMBL6263949, Tetraisopropyl pyrophos-phoramide, BDBM10625, IOIMDJXKIMCMIG-UHFFFAOYSA-, C12H32N4O3P2, IOIMDJXKIMCMIG-UHFFFAOYSA-N, HMS2236P05, HMS3263N09, HMS3372B16, ZINC2036756, Tox21_501184, ACM513008, AKOS016015535, CCG-205258, LP01184, NCGC00016002-01, NCGC00016002-02, NCGC00016002-03, NCGC00016002-04, NCGC00016002-05, NCGC00094438-01, NCGC00094438-02, NCGC00261869-01, CJ-32019, SMR001230724, LS-175247, EU-0101184, FT-0632259, N,N',N'',N -tetra-iso-Propylpyrophosphoramide, T 1505, C-50461, SR-01000076147, SR-01000076147-1, Pyrophosphorotetramide, N,N',N'',N'''-tetra(isopropyl)-, Tetraisopropyl pyrophosphoramide, butyrylcholinesterase inhibitor, ({[bis(propan-2-ylamino)phosphoryl]oxy}(propan-2-ylamino)phosphoryl)(propan-2-yl)amine, N-[bis(propan-2-ylamino)phosphoryloxy-(propan-2-ylamino)phosphoryl]propan-2-amin, N-[bis(propan-2-ylamino)phosphoryloxy-(propan-2-ylamino)phosphoryl]propan-2-amine, InChI=1/C12H32N4O3P2/c1-9(2)13-20(17,14-10(3)4)19-21(18,15-11(5)6)16-12(7)8/h9-12H,1-8H3,(H2,13,14,17)(H2,15,16,18)

ID: 968

InChIKey: IOJBFNDOWJEKLP-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=NN=C(N2N)C3=CC=C(C=C3)OC

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 10851455
synonyms found at PubChem are:
4H-1,2,4-Triazol-4-amine, 3,5-bis(4-methoxyphenyl)-, 93016-27-4, ACMC-20lwyi, CTK3G9779, DTXSID40445855, 3,5-bis(4-methoxyphenyl)-4-amino-1,2,4-triazole, 3,5-Bis(4-methoxyphenyl)-4H-1,2,4-triazole-4-amine

ID: 969

InChIKey: IORPOFJLSIHJOG-UHFFFAOYSA-N
SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)CC#C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 99562
synonyms found at PubChem are:
14114-46-6, 3,7-Dimethyl-1-propargylxanthine, DMPX, 3,7-Dimethyl-1-(prop-2-yn-1-yl)-1H-purine-2,6(3H,7H)-dione, UNII-5YFR5SPS6T, 3,7-Dimethyl-I-propargylxanthine, 5YFR5SPS6T, 3,7-Dimethyl-1-(2-propynyl)xanthine, NSC 242985, CHEMBL282038, NSC-242985, 3,7-dimethyl-1-(prop-2-ynyl)-1H-purine-2,6(3H,7H)-dione, 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(2-propynyl)-, Lopac-D-134, AC1Q6LFB, AC1L40ZE, Lopac0_000428, SCHEMBL44805, MLS000862190, CTK8B7549, DTXSID30161577, IORPOFJLSIHJOG-UHFFFAOYSA-N, HMS2231E22, HMS3261E18, HMS3370E07, BCP26239, ZINC1764195, Tox21_500428, 3,7-dimethyl-1-(2-propyn-1-yl)-3,7-dihydro-1h-purine-2,6-dione, 6856AA, ANW-57638, BDBM50008386, MFCD00078576, NSC242985, AKOS016001452, CCG-204520, CS-W004425, LP00428, NCGC00015312-01, NCGC00015312-02, NCGC00015312-03, NCGC00015312-04, NCGC00015312-05, NCGC00093849-01, NCGC00093849-02, NCGC00093849-03, NCGC00261113-01, AJ-31622, CJ-29818, DS-16284, SMR000326953, AX8083132, LS-184216, D-134, EU-0100428, FT-0614782, 3,7-dimethyl-1-prop-2-ynylpurine-2,6-dione, C-56140, SR-01000075249, J-007467, SR-01000075249-1, 3,7-dimethyl-1-(prop-2-yn-1-yl)purine-2,6-dione, 3,7-Dimethyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione, 3,7-Dimethyl-1-propargylxanthine, >=98% (HPLC), powder, 3,7-dihydro-3,7-dimethyl-1-(2-propynyl)-1H-purine-2,6-dione, 1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(2-propyn-1-yl)-

ID: 970

InChIKey: IOSAAWHGJUZBOG-MNOVXSKESA-N
SMILES: CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C1N=CN=C2N

biological descriptors:

CFTR relevance: Phosphodiesterase 2 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"PC Chao" "KL Hamilton"

CID is 149784
synonyms found at PubChem are:
(2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol, CHEMBL50378, (2R,3S)-EHNA, CHEBI:63058, 79813-68-6, (2R,3S)-3-(adenin-9-yl)-2-nonanol, (2R,3S)-9-(2-hydroxy-3-nonyl)adenine, 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (R*,S*)-(+-)-, EHNA, 79763-32-9, (R,S)-6-amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, (2R,3S)-3-(6-aminopurin-9-yl)nonan-2-ol, EHNA.HCl, 51350-19-7, HWC 52, eh-na, Tocris-1261, AC1Q2VOZ, (-)-erythro-9-(2-hydroxy-3-nonyl)adenine, AC1L3ZQ9, Lopac0_000504, BSPBio_001061, KBioGR_000401, KBioSS_000401, SCHEMBL1742893, DTXSID6043880, BCBcMAP01_000066, CTK2H9386, KBio2_000401, KBio2_002969, KBio2_005537, KBio3_000761, KBio3_000762, IOSAAWHGJUZBOG-MNOVXSKESA-N, Bio1_000430, Bio1_000919, Bio1_001408, Bio2_000361, Bio2_000841, HMS1792E03, HMS1990E03, HMS3403E03, ZINC1614354, (R*,S*)-(+-)-6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, (R-(R*,S*))-6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, BDBM50034908, CCG-36414, 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (R-(R*,S*))-, 3-(6-Amino-purin-9-yl)-nonan-2-ol, IDI1_002116, SMP2_000310, NCGC00025087-01, NCGC00025087-02, NCGC00025087-03, NCGC00025087-04, NCGC00025087-05, NCGC00025087-06, (EHNA)3-(6-Amino-purin-9-yl)-nonan-2-ol, 3-(6-Amino-purin-9-yl)-nonan-2-ol(EHNA), (2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol, (2R,3S)-3-(6-Amino-9H-purine-9-yl)2-nonanol, (2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol, BRD-K27450477-001-03-9, (r-6-amino-beta-hexyl-alpha-methyl-9h-purine-9-ethanol

ID: 971

InChIKey: IOSAAWHGJUZBOG-UHFFFAOYSA-N
SMILES: CCCCCCC(C(C)O)N1C=NC2=C1N=CN=C2N

biological descriptors:

CFTR relevance: Phosphodiesterase 2 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"PC Chao" "KL Hamilton"

CID is 3206
synonyms found at PubChem are:
9-(2-hydroxy-3-nonyl)adenine, erythro-9-(2-hydroxy-3-nonyl)adenine, EHNA, 59262-86-1, 3-(6-amino-9h-purin-9-yl)nonan-2-ol, C14H23N5O, 3-(6-aminopurin-9-yl)nonan-2-ol, 6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, Erythro-9-[3-(2-hydroxynonyl)] adenine, 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, threo-9-(2-hydroxy-3-nonyl)adenine, NSC 263164, erythro-9-(2-hydroxynon-3-yl)adenine, erythro-9-(3-(2-hydroxynonyl))adenine, AC1L1FEW, AC1Q4VGH, 51350-19-7, 6-amino beta-hexyl alpha-methyl-9H-purine-9-ethanol, SCHEMBL1740490, BDBM22926, CTK5A9678, 9-(2-hydroxy-3-nonyl) adenine, DTXSID70110044, (R*,S*)-6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (R*,S*)-, AKOS030562483, 9-erythro-(2-hydroxy-3-nonyl)adenine, 3-(6-Amino-9H-purin-9-yl)-2-nonanol, LS-176000, FT-0639990, 9H-Purine-9-ethanol,6-amino-b-hexyl-a-methyl-, 6-Amino-9-[1-(1-hydroxyethyl)heptyl]-9H-purine, L001098

ID: 972

InChIKey: IOSAAWHGJUZBOG-WDEREUQCSA-N
SMILES: CCCCCC[C@H]([C@H](C)O)N1C=NC2=C1N=CN=C2N

biological descriptors:

CFTR relevance: Phosphodiesterase 2 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"PC Chao" "KL Hamilton"

CID is 149790
synonyms found at PubChem are:
(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol, (+)-EHNA, (2S,3R)-EHNA, CHEMBL296435, CHEBI:63059, (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol, 79813-69-7, (S,R)-6-amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, HWC 46, 2z7g, AC1L3ZQL, (+)-erythro-9-(2-Hydroxy-3-nonyl)adenine, D0V4WB, SCHEMBL1742728, BDBM28393, CTK2H9986, IOSAAWHGJUZBOG-WDEREUQCSA-N, EH9, ZINC1558334, (S-(R*,S*))-6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol, 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (S-(R*,S*))-, AKOS030531307, DB07711, Erythro-9-(2 Hydroxy 3-Nonyl)Adenine, NCI60_002100

ID: 973

InChIKey: IOTBHDLEPFTSHN-QRUJPHNVSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@]([C@H](C[C@H](C2(C)C)O)O)(C3[C@@]1([C@]45[C@H](O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708624
synonyms found at PubChem are:
KBio1_001297, Spectrum_000515, SpecPlus_000257, Spectrum2_000751, Spectrum3_000079, Spectrum4_001362, Spectrum5_000004, BSPBio_001897, KBioGR_001624, KBioSS_000995, DivK1c_006353, SPBio_000762, 1,3-DIDEACETYLKHIVORIN, KBio2_000995, KBio2_003563, KBio2_006131, KBio3_001117, CCG-39660, NCGC00178918-01, BRD-A67787745-001-02-5

ID: 974

InChIKey: IOTBHDLEPFTSHN-YUJBZOGSSA-N
SMILES: CC(=O)O[C@@H]1CC2[C@@](C3[C@@]1([C@]45[C@H](O4)C(=O)OC(C5(CC3)C)C6=COC=C6)C)(C(C[C@H](C2(C)C)O)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "D Zhang" "Y Luo" "JW Hanrahan" "R Robert" "KA Teske" "GW Carlile"

CID is 88984420
synonyms found at PubChem are:
SCHEMBL12948351

ID: 975

InChIKey: IOUNQDKNJZEDEP-UHFFFAOYSA-N
SMILES: CCOP(=S)(OCC)SCN1C2=C(C=C(C=C2)Cl)OC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4793
synonyms found at PubChem are:
phosalone, 2310-17-0, Zolone, Fosalon, Benzophosphate, Azofene, Fozalon, Phosalon, Phozalon, Rubitox, Zolone PM, Agria 1060 A, Benzphos, Zone, Chipman 11974, Agria 1060, Zolone DT, Rhodia RP 11974, Phosalone 35 EC, Niagara 9241, Caswell No. 660A, Fosalone, Phasolon, Zoolon, Phosalone [ANSI:BSI:ISO], UNII-448B85HT8M, CCRIS 2000, HSDB 4050, P 974, 11 974 rp, NIA-9241, NPH-1091, EINECS 218-996-2, ENT 27,163, EPA Pesticide Chemical Code 097701, BRN 0694650, 6-chloro-3-(diethoxyphosphinothioylsulfanylmethyl)-1,3-benzoxazol-2-one, AI3-27163, RP 11,974, CHEBI:8121, Phosphorodithioic acid, O,O-diethyl ester, S-ester with 6-chloro-3-(mercaptomethyl)-2-benzoxazolinone, P-974, 448B85HT8M, S-(6-Chloro-2-oxobenzoxazolin-3-yl)methyl diethyl phosphorothiolothionate, Phosphorodithioic acid, S-((6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl) O,O-diethyl ester, Phosphorodithioic acid, S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl ester, S-6-Chloro-2,3-dihydro-2-oxo-benzoxazol-3-ylmethyl O,O-diethyl phosphorodithioate, 3-Diethyldithiophosphorylmethyl-6-chlorobenzoxazolone-2, 3-(O,O-Diethyldithiophosphorylmethyl)-6-chlorobenzoxazolinone, 3-(O,O-Diethyldithiophosphorylmethyl)-6-chlorobenzoxazolone, 6-Chloro-3-(O,O-diethyldithiophosphorylmethyl)benzoxazolone, 3-[O,O-(Diethyldithiophosphoryl)methyl]-6-chlorobenzoxazolinone, O,O-Diethyl S-(6-chlorobenzoxazolinyl-3-methyl) dithiophosphate, O,O-Diethyl-S-(6-chlorobenzoxazonyl-3-methyl) dithiophosphate, 6-Chloro-3-diethoxyphosphinothioylthiomethyl-1,3-benzoxazol-2(3H)-one, DSSTox_CID_4259, 3-(6-Chloro-2-oxobenzoxazolin-3-yl)methyl O,O-diethyl phosphorothiolothionate, 3-(6-Chloro-2-oxobenzoxazolin-3-yl)methyl-O,O-diethyl phosphorothiolothionate, O,O-Diethyl S-((6-chloro-2-oxobenzoxazolin-3-yl)methyl) phosphorodithioate, O,O-Diethyl-S-(6-chloro-2-oxo-benzoxazolin-3-yl)methyl-phosphorothiolothionate, O,O-Diethyl-S-(6-chloro-2-oxobenzoxazolin-3-yl-methyl)-phosphorodithioate, Phosphorodithioic acid-S-ester of 6-chloro-3-mercaptomethylbenzoxazyol-2-one, S-((3-Benzoxazolinyl-6-chloro-2-oxo)methyl) O,O-diethyl phosphorodithioate, S-((6-Chloro-2-oxo-3(2H)-benzoxazolyl)methyl) O,O-diethyl phosphorodithioate, DSSTox_RID_77344, O,O-Diaethyl-S-(6-chlor-2-oxo-ben(b)-1,3-oxalin-3-yl)-methyl-dithiophosphat [German], O,O-Diethyl phosphorodithioate, S-ester with 6-chloro-3-(mercaptomethyl)-2-benzoxazolinone, O,O-Diethyl-S-((6-chloor-2-oxo-benzoxazolin-3-yl)-methyl)-dithiofosfaat [Dutch], O,O-Dietil-S-((6-cloro-2-oxo-benzossazolin-3-il)-metil)-ditiofosfato [Italian], S-(6-Chloro-3-(mercaptomethyl)-2-benzoxazolinone) O,O-diethyl phosphorodithioate, S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] o,o-diethyl dithiophosphate, S-6-Chloro-2,3-dihydro-2-oxo-1,3-benzoxazol-3-ylmethyl O,O-diethyl phosphorodithioate, DSSTox_GSID_24259, Phosalone, analytical standard, fozalone, phoazlone, phozalone, S-((6-Chloro-2-oxo-3H)-benzoxazolylmethyl)O,O-diethyl phosphorodithioate, S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate, 54182-71-7, CAS-2310-17-0, Saliphos, Spectrum_001797, SpecPlus_000388, AC1L1IYW, Spectrum2_001862, Spectrum3_000814, Spectrum4_000654, Spectrum5_001938, CBMicro_004841, C12H15ClNO4PS2, Oprea1_627117, SCHEMBL26843, BSPBio_002307, KBioGR_001027, KBioSS_002290, SPECTRUM330022, BIDD:ER0422, DivK1c_006484, SPBio_001704, CHEMBL1528531, DTXSID1024259, CTK4J9916, IOUNQDKNJZEDEP-UHFFFAOYSA-, KBio1_001428, KBio2_002288, KBio2_004856, KBio2_007424, KBio3_001807, IOUNQDKNJZEDEP-UHFFFAOYSA-N, MolPort-002-130-334, CCG-2037, HY-B2029, NIA 9241, SMSF0001368, Tox21_202294, Tox21_300811, ENT 27163, O,O-Dietil-S-((6-cloro-2-oxo-benzossazolin-3-il)-metil)-ditiofosfato, AKOS015896127, O,O-Diaethyl-S-(6-chlor-2-oxo-ben(b)-1,3-oxalin-3-yl)-methyl-dithiophosphat, O,O-Diethyl-S-((6-chloor-2-oxo-benzoxazolin-3-yl)-methyl)-dithiofosfaat, S-((6-chloro- 2-oxo-3H)-benzoxazolylmethyl)O,O-diethyl phosphorodithioate, ACM2310170, CB06818, CS-5216, MCULE-7104953013, Phosalone 10 microg/mL in Cyclohexane, Phosalone 10 microg/mL in Acetonitrile, Phosalone 100 microg/mL in Cyclohexane, NCGC00094519-01, NCGC00094519-02, NCGC00094519-03, NCGC00094519-04, NCGC00094519-05, NCGC00094519-06, NCGC00094519-07, NCGC00178712-01, NCGC00254715-01, NCGC00259843-01, 11974 RP, AC-20097, AN-50687, BC216073, CC-33746, RP 11974, ZB015215, BIM-0004803.P001, LS-108056, TR-010787, FT-0603602, Phosalone, PESTANAL(R), analytical standard, C11028, 310P170, C-21067, I06-1637, J-014987, BRD-K71671197-001-02-6, I14-18605, 6-Chloro-3-[O,O-(diethyldithiophosphoryl)methyl]benzoxazolone, O,O-DIETHYL S-(6-CHLOROBENZOXZAOLON-3-YL)METHYL PHOSPHORODITHIOATE, O,O-Diethyl phosphorodithioate S-ester with 6-chloro-3-(mercaptomethyl)-2-benzoxazolinone, Phosphorodithioic acid, S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl]O,O-diethyl ester, S-((6-Chloro-2-oxobenzo[d]oxazol-3(2H)-yl)methyl) O,O-diethyl phosphorodithioate, S-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)methyl O,O-diethyl phosphorodithioate, S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate #, S-[(6-Chloro-2-oxo-3(2H)-benzoxazoly)methyl] O,O-diethyl phosphorodithioate, S-[(6-Chloro-2-oxo-3(2H)-benzoxazolyl)methyl]phosphorodithioic acid O,O-diethyl ester, 11129-09-2, 29562-46-7, diethyl {[(6-chloro-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]sulfanyl}(sulfanylidene)phosphonite, InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3

ID: 976

InChIKey: IOVDQEIIMOZNNA-MHKBYHAFSA-N
SMILES: C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5282483
synonyms found at PubChem are:
FLUPENTIXOL DIHYDROCHLORIDE, Flupenthixol dihydrochloride, Emergil, 51529-01-2, cis-(Z)-Flupenthixol dihydrochloride, 2413-38-9, (Z)-Flupenthixol dihydrochloride, Flupenthixol, dihydrochloride, Flupentixol hydrochloride, Fupentixol dihydrochloride, UNII-96L0Z069N1, EINECS 219-321-4, FX 703, NSC 170952, Flupentixol dihydrochloride cis-(Z), 96L0Z069N1, Flupentixol HCl, N 7009, 1-Piperazineethanol, 4-(3-(2-trifluoromethylthioxanth-9-ylidene)propyl)-, dihydrochloride, 4-(3-(2-(Trifluoromethyl)thioxanthen-9-ylidene)propyl)-1-piperazineethanol dihydrochloride, (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride, (Z)-4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol dihydrochloride, 2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol dihydrochloride, 4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethanol dihydrochloride, Thioxanthene, 9-(3-(4-(2-hydroxyethyl)piperazinyl)propylidene)-2-trifluoromethyl-, dihydrochloride, Prestwick_902, AC1NR051, SCHEMBL1153162, CHEMBL1496351, EBD3474, EX-A352, Flupentixol dihydrochloride (JAN), MolPort-003-941-351, HMS1569C21, Cis(Z)-Flupentixol Dihydrochloride, Tox21_500528, AKOS025401529, AC-2136, ACM2413389, AN-8191, CCG-221832, LP00528, NCGC00093921-01, NCGC00261213-01, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride, (Z)-, AN-14259, KB-310823, LS-153618, B7578, EU-0100528, F-114, D02236, 529F012, SR-01000076232, J-015359, SR-01000076232-1, UNII-HAT84MLQ6Z component IOVDQEIIMOZNNA-MHKBYHAFSA-N, cis-(Z)-Flupenthixol dihydrochloride, >=98% (HPLC), solid, (Z)-2-(4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol dihydrochloride, (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazine-ethanol dihydrochloride, (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol dihydrochloride, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride (9CI), 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl)-, dihydrochloride, 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl)-, dihydrochloride (8CI), 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride, AKOS015896374, AM84819, I06-1949

ID: 977

InChIKey: IPANUAHQWFDVAG-BTJKTKAUSA-N
SMILES: CN1CCC(=C2C3=CC=CC=C3SC4=CC=CC=C42)CC1.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5702167
synonyms found at PubChem are:
PIMETHIXENE MALEATE, UNII-U22U244M9X, 13187-06-9, EINECS 236-141-1, 9-(N-Methyl-piperidyliden-4)thioxane maleate, BP-400, 9-(1-Methyl-4-piperidylene)thioxanthene maleate, U22U244M9X, Thioxanthene, 9-(1-methyl-4-piperidylene)-, maleate, NCGC00094897-01, 1-Methyl-4-(9H-thioxanthen-9-ylidene)piperidinium hydrogen maleate, DSSTox_CID_25863, DSSTox_RID_81183, DSSTox_GSID_45863, Pimethixen maleate salt, Pimethixene maleate salt, SR-01000872656, CAS-13187-06-9, Prestwick_656, AC1NWASZ, SCHEMBL301225, SPECTRUM1501114, CHEMBL1523827, DTXSID7045863, HMS501F14, HMS1568L10, HMS1921F09, HMS2095L10, HMS3712L10, Pharmakon1600-01501114, Tox21_111354, CCG-39945, NSC757828, AKOS027379089, Tox21_111354_1, NSC-757828, NCGC00016698-06, NCGC00094897-02, LS-153629, Pimethixene maleate salt, analytical standard, J-006075, SR-01000872656-1, SR-01000872656-2, 1-METHYL-4-[THIOXANTHEN-9-YLIDENE]PIPERIDINE MALEATE SALT, (Z)-but-2-enedioic acid; 1-methyl-4-thioxanthen-9-ylidenepiperidine, KB-302616, Piperidinium,1-methyl-4-(9H-thioxanthen-9-ylidene)-(2Z)-2-butenedioate (1:1)

ID: 978

InChIKey: IPBCWPPBAWQYOO-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCSCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 114924
synonyms found at PubChem are:
Tetradecylthioacetic acid, CMTD, 1-(Carboxymethylthio)tetradecane, 1-Mono(carboxymethylthio)tetradecane, UNII-7ZU5I25S2O, Tetradecylsulfanyl-acetic acid, 7ZU5I25S2O, Acetic acid, (tetradecylthio)-, Q-201808, (tetradecylsulfanyl)acetic acid, SR-01000076149, AC1Q5WVH, Spectrum5_001951, Lopac-T-1698, AC1L3G7T, Lopac0_001155, 2-(Tetradecylthio)acetic acid, SCHEMBL207756, 2-tetradecylsulfanylacetic acid, CHEMBL187734, DTXSID0040759, C16H32O2S, C16H32SO2, CHEBI:94633, IPBCWPPBAWQYOO-UHFFFAOYSA-N, Acetic acid, 2-(tetradecylthio)-, HMS3263H11, ZINC8035065, Tox21_501155, AKOS005067132, API0015093, CCG-205229, LP01155, NCGC00016005-01, NCGC00016005-02, NCGC00016005-03, NCGC00016005-04, NCGC00016005-05, NCGC00016005-06, NCGC00094417-01, NCGC00094417-02, NCGC00094417-03, NCGC00094417-04, NCGC00261840-01, BC215993, CC-34853, Tetradecylthioacetic acid, >=97% (NMR), LS-174239, EU-0101155, FT-0634553, T 1698, 921T202, C-18149, SR-01000076149-1, SR-01000076149-4, BRD-K47539947-001-01-1

ID: 979

InChIKey: IPEHBUMCGVEMRF-UHFFFAOYSA-N
SMILES: C1=CN=C(C=N1)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1046
synonyms found at PubChem are:
pyrazinamide, pyrazinecarboxamide, pyrazine-2-carboxamide, 98-96-4, Zinamide, pyrazinoic acid amide, 2-Pyrazinecarboxamide, Aldinamide, Aldinamid, Pirazinamid, Pyrazineamide, Pyrafat, Tebrazid, Unipyranamide, Farmizina, Pirazimida, pyrazine carboxylamide, Eprazin, Novamid, 2-Carbamylpyrazine, Pyrazinecarboxylic acid amide, Pyrazinamidum, Pirazinamida, Tisamid, Isopas, Pirazinamide, Pyrazine carboxamide, Pezetamid, Piraldina, Braccopiral, Corsazinmid, Pyrazinamdie, Dipimide, Lynamide, Prazina, Pyramide, Pyrazide, Tebrazio, Zinastat, Rozide, Pirazinamide [DCIT], MK 56, PZA, D-50, Pyrazinamidum [INN-Latin], NCI-C01785, Pirazinamida [INN-Spanish], C5H5N3O, Pharozinamide, Pyrazinamid, P ezetamid, pms-Pyrazinamide, D-50 (VAN), UNII-2KNI5N06TI, DRG 0124, NSC 14911, CCRIS 545, Pyrazinamide (TN), 2-carbamyl pyrazine, Pyrazinamide [INN:BAN:JAN], HSDB 3576, Pyrazinoic acid am ide, T 165, Pyrazinamide BP 2000, EINECS 202-717-6, BRN 0112306, 2KNI5N06TI, MLS000069730, AZT + Pyrazinamide combination, CHEBI:45285, Pyrazine-2-carboxylic acid amide, IPEHBUMCGVEMRF-UHFFFAOYSA-N, NSC14911, Pyrazinamide (Pyrazinoic acid amide), NCGC00015833-09, SMR000036662, DSSTox_CID_1215, P 7136, DSSTox_RID_76014, DSSTox_GSID_21215, Rifafour, CAS-98-96-4, Rifafour e-200, SR-01000076077, pyramizade, pyrazinamida, Pyrizinamide, pyrazine amide, alpha-pyrazinamide, Pyrazinamide,(S), Pyrazinamide [USP:INN:BAN:JAN], 2-Carbamoylpyrazine, Prestwick_811, ACMC-20aive, 2-pyrazine carboxamide, Spectrum_000902, Opera_ID_735, AC1L1ALT, AC1Q4ZGM, Prestwick0_000514, Prestwick1_000514, Prestwick2_000514, Prestwick3_000514, Spectrum2_001305, Spectrum3_001046, Spectrum4_001186, Spectrum5_001026, Lopac-P-7136, CHEMBL614, D0XF8W, WLN: T6N DNJ BVZ, pyrazine-2-carboximidic acid, Lopac0_001011, SCHEMBL24102, BSPBio_000467, BSPBio_002572, KBioGR_001851, KBioSS_001382, 5-25-04-00178 (Beilstein Handbook Reference), KSC449E8F, MLS002222347, BIDD:GT0228, DivK1c_000241, SPECTRUM1500518, SPBio_001369, SPBio_002388, BPBio1_000515, EBD430, GTPL7287, ZINC2005, DTXSID9021215, 2-pyrazinecarboxylic acid amide;, HMS500M03, KBio1_000241, KBio2_001382, KBio2_003950, KBio2_006518, KBio3_001792, Pyrazinamide (JP15/USP/INN), Pyrazinamide (JP17/USP/INN), MolPort-001-770-770, MolPort-023-219-632, NINDS_000241, BDBM228814, HMS1569H09, HMS1920N08, HMS2092E09, HMS2096H09, HMS2235G17, HMS3259O04, HMS3263K03, HMS3371G09, HMS3655A10, HMS3713H09, KUC109577N, Pharmakon1600-01500518, ACT01761, HY-B0271, KS-00000B7D, KSC-27-052E, Tox21_110237, Tox21_202059, Tox21_302771, Tox21_501011, ANW-75384, BBL010592, CCG-39243, MFCD00006132, NSC-14911, NSC757304, s1762, SBB004276, STK801661, AKOS000120280, Tox21_110237_1, CS-2260, DB00339, LP01011, LS-2053, MCULE-6846697749, NC00534, NSC-757304, Pyrazinecarboxamide, analytical standard, IDI1_000241, NCGC00015833-01, NCGC00015833-02, NCGC00015833-03, NCGC00015833-04, NCGC00015833-05, NCGC00015833-06, NCGC00015833-07, NCGC00015833-08, NCGC00015833-10, NCGC00015833-11, NCGC00015833-12, NCGC00015833-15, NCGC00015833-16, NCGC00090695-01, NCGC00090695-03, NCGC00090695-04, NCGC00090695-05, NCGC00090695-06, NCGC00090695-07, NCGC00256336-01, NCGC00259608-01, NCGC00261696-01, Pyrazinoic acid amide; pyrazinamide; PZA, AJ-08121, CAS- 98-96-4, CPD000036662, SAM002554927, SC-46323, TS-01626, SBI-0050984.P004, AB0008224, AB2000278, AJ-138256, DB-002866, KB-204556, ST2413707, TR-030381, AB00052083, B2122, BB 0253141, EU-0101011, FT-0659757, P0633, ST45022155, C01956, D00144, J10111, M-7421, AB00052083-16, AB00052083_17, AB00052083_18, AC-907/25014068, I14-6758, SR-01000076077-1, SR-01000076077-4, SR-01000076077-6, W-100059, Z33546644, Pyrazinamide, British Pharmacopoeia (BP) Reference Standard, Pyrazinamide, European Pharmacopoeia (EP) Reference Standard, Pezetamid;Pyrafat;Zinamide;Tebrazid;Pyrafat;Pyrazinoic acid amide, Pyrazinamide, United States Pharmacopeia (USP) Reference Standard, InChI=1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9, Pyrazinamide, Pharmaceutical Secondary Standard; Certified Reference Material, Pyrazinoic acid amide, Pezetamid, Pyrafat, Zinamide, Tebrazid, Pyrafat, Pyrazinamide

ID: 980

InChIKey: IPMRJRMWTMGXAM-UHFFFAOYSA-N
SMILES: CCOC(=O)C(=O)C1(C(C(=O)C2=C(C=C(C=C2O1)OC)OC)C3=CC=CC=C3)C(=O)OCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 6708763
synonyms found at PubChem are:
2-ETHOXYCARBONYL-2-ETHOXYOXALOYLOXYDIHYDROCHRYSIN DIMETHYL ETHER, KBio2_003581, Spectrum_000533, SpecPlus_000751, AC1O8FNK, Spectrum2_001932, Spectrum3_000706, Spectrum4_001491, Spectrum5_000221, BSPBio_002491, KBioGR_002121, KBioSS_001013, SPECTRUM200141, DivK1c_006847, SPBio_001963, CHEMBL1414316, KBio1_001791, KBio2_001013, KBio2_006149, KBio3_001711, CCG-39433, NCGC00095815-01, NCGC00095815-02, ethyl 2-(2-ethoxy-2-oxoacetyl)-5,7-dimethoxy-4-oxo-3-phenyl-3H-chromene-2-carboxylate

ID: 981

InChIKey: IPMYMEWFZKHGAX-ZKSIBHASSA-N
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=O)C(=C4C(=C3)C(=CC(=C4O)O)[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 114777
synonyms found at PubChem are:
Theaflavin, Theaflavine, 4670-05-7, (-)-Theaflavin, UNII-1IA46M0D13, 1IA46M0D13, 1,8-Bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-5H-benzocyclohepten-5-one, 1,8-Bis((2R,3R)-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one, Theaflavin 1, Spectrum_000527, SpecPlus_000296, AC1L3FXZ, Spectrum2_001765, Spectrum3_000698, Spectrum4_001488, Spectrum5_000195, SCHEMBL19551, BSPBio_002455, KBioGR_002095, KBioSS_001007, SPECTRUM200111, DivK1c_006392, SPBio_001629, Theaflavin, analytical standard, CHEMBL346119, IPMYMEWFZKHGAX-ZKSIBHASSA-, KBio1_001336, KBio2_001007, KBio2_003575, KBio2_006143, KBio3_001675, DTXSID40196916, CHEBI:136609, IPMYMEWFZKHGAX-ZKSIBHASSA-N, MolPort-027-720-916, 5H-Benzocyclohepten-5-one, 1,8-bis((2R,3R)-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-, 5H-Benzocyclohepten-5-one, 1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-3,4,6-trihydroxy-, HY-N0243, ZINC3978446, CCG-38815, AKOS016009349, CS-5885, SDCCGMLS-0066962.P001, KS-00000H65, NCGC00178645-01, AT-37524, ST2407752, Y0203, 3,4,5-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-2-chromanyl]-6-benzo[7]annulenone, 3,4,6-Trihydroxy-1,8-bis(3|A,5,7-trihydroxy-2|A-chromanyl)-5H-benzocyclohepten-5-one, 3,4,6-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]benzo[7]annulen-5-one, [2R-[2|A(2R*,3R*),3|A]]-1,8-Bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one, 1,8-Bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5H-benzocyclohepten-5-one, 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6H-benzo[7]annulen-6-one, 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6H-benzocyclohepten-6-one, 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-6-one, 3,4,6-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-5H-benzo[7]annulen-5-one, 5H-Benzocyclohepten-5-one,1,8-bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-, InChI=1/C29H24O12/c30-11-3-17(32)15-8-21(36)28(40-23(15)5-11)10-1-13-14(7-20(35)27(39)25(13)26(38)19(34)2-10)29-22(37)9-16-18(33)4-12(31)6-24(16)41-29/h1-7,21-22,28-33,35-37,39H,8-9H2,(H,34,38)/t21-,22-,28-,29-/m1/s1

ID: 982

InChIKey: IPQVTOJGNYVQEO-KGFNBKMBSA-N
SMILES: C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C([C@@H]2[C@@H]5C6=C(C(=CC=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 73111
synonyms found at PubChem are:
Sennoside A, 81-27-6, Senna extract, Senokot, UNII-2F1O30GVXH, EINECS 201-339-9, NSC 112929, 2F1O30GVXH, CHEBI:9112, 8013-11-4, C42H38O20, sennoside, Dosaflex, Gentlax, Glaxenna, Sennalax, Senolax, Amyran, Exprep, Moivat, Senan, Sennae folium, Black Draught, NSC112929, Sennoside-A, Tisasen A, Senna (powdered), Sennoside A, G, NCGC00095095-01, GLYSENNIDE, SENNA, AC1L2JAB, DSSTox_CID_3576, D0Z2LG, Sennosides A + B 99%, DSSTox_RID_77089, DSSTox_GSID_23576, SCHEMBL440792, Ex-Lax Regular Strength Pills, CCRIS 7489, MEGxp0_001902, CHEMBL2368547, DTXSID1023576, NIOSH/VT6020000, ACon0_001464, BDBM92481, MolPort-001-742-607, (9,9'-Bianthracene)-2,2'-dicarboxylic acid, 5,5'-bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (R*,R*)-, Tox21_111420, LMPK13040016, AKOS015960468, ZINC169296903, AC-6075, MCULE-8163541496, CAS-81-27-6, SMP1_000271, 85085-71-8, AN-42213, CC-34399, O915, SC-17335, LS-177600, N1678, S4033, VT60200000, C10404, 151S527, C-23560, Q-201704, UNII-9VK7V8762D component IPQVTOJGNYVQEO-KGFNBKMBSA-N, (-)-(9R*,9'R*)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid, (9,9'-Bianthracene)-2,2'-dicarboxylic acid, 5,5'-bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (R*,R*)- (VAN), (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid, (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-9H-anthracene-2-carbo, (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-9H-anthracene-2-carboxylic acid, (9R*,9'R*)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid, (9R,9'R)-4,4'-dihydroxy-10,10'-dioxo-5,5'-bis((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid, (9R,9'R)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid, [9,9' -Bianthracene] -2,2' -dicarboxylic acid, 5,5' -bis(.beta. -D-glucopyranosyloxy) -9,9' ,10,10' -tetrahydro-4,4' - dihydroxy-10,10' -dioxo-, (R*,R*) - (9CI), [9,9'-Bianthracene]-2,2'-dicarboxylicacid, 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'R)-

ID: 983

InChIKey: IPSYPUKKXMNCNQ-PFHKOEEOSA-N
SMILES: CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=C(N=C3NCC4=CC(=CC=C4)I)Cl)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3035850
synonyms found at PubChem are:
2-Cl-IB-Meca, 163042-96-4, Cl-IB-MECA, Namodenoson, C-Ibza-MU, CF-102, CI-IB-MECA, (2S,3S,4R,5R)-5-(2-Chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide, UNII-Z07JR07J6C, CF102, 2Cl-IB-MECA, CHEMBL431733, Z07JR07J6C, 2-Chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide, (2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide, 1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE, 1-(2-Chloro-6-(((3-iodophenyl)methyl)amino)-9H-purin-9-yl)-1-deoxy-N-methyl-beta-D-Ribofuranuronamide, CF 102, Namodenoson [USAN], 2-Chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide, C1-IB-MECA, D0U0KR, AC1MI03J, 2-Chloro-N(6)-(3-iodobenzyl)-9-(5-(methylcarbamoyl)-beta-D-ribofuranosyl)adenine, GTPL457, MLS002153535, SCHEMBL1170028, BDBM21221, DTXSID80167504, MolPort-003-940-691, HMS2235L10, CF-102(2-Cl-IB-MECA), ZINC3995845, AKOS022181265, AM84557, CS-5932, DB12885, NCGC00025001-02, AC-27390, AK-60479, AN-17022, DS-16397, HY-12365, SMR001230862, AB0047892, Chloro-IB-MECA, solid, >=98% (HPLC), KB-276752, B6597, ST24034136, J-009992, 2-chloro-N6-(3-iodobenzyl)adenosine-5-N-methylcarboxamide, 2-Chloro-N6-(3-iodobenzyl)-adenosine-5 inverted exclamation marka-N-methyluronamide, (2S,3S,4R,5R)-5-(2-chloro-6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide, (2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide, (2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide, 1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-?-D-ribofuranuronamide, beta-D-Ribofuranuronamide, 1-(2-chloro-6-(((3-iodophenyl)methyl)amino)-9H-purin-9-yl)-1-deoxy-N-methyl-

ID: 984

InChIKey: IPWKIXLWTCNBKN-UHFFFAOYSA-N
SMILES: CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 28061
synonyms found at PubChem are:
Ornidazole, 16773-42-5, Tiberal, Madelen, Ornidazolum, Ro 7-0207, Ornidazol, 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole, 1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol, 1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)-2-propanol, Ornidal, 1-(2-Hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole, Ornidazole [USAN:INN], Ornidazol [INN-Spanish], Ornidazolum [INN-Latin], NSC 95075, CCRIS 9030, EINECS 240-826-0, alpha-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol, Ro-70207, 1H-Imidazole-1-ethanol, alpha-(chloromethyl)-2-methyl-5-nitro-, BRN 0614299, C7H10ClN3O3, MLS000028628, alpha-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol, alpha-(Chloromethyl)-2-methyl-5-nitroimidazole-1-ethanol, CHEBI:75176, NSC95075, .alpha.-(Chloromethyl)-2-methyl-5-nitroimidazole-1-ethanol, SMR000058726, Imidazole-1-ethanol, .alpha.-(chloromethyl)-2-methyl-5-nitro-, 1H-Imidazole-1-ethanol, .alpha.-(chloromethyl)-2-methyl-5-nitro-, alpha-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol [German], DSSTox_CID_25420, DSSTox_RID_80868, DSSTox_GSID_45420, Q-201520, 1-[3-Chloro-2-hydroxypropyl]-2-methyl-5-nitroimidazole, 1-chloro-3-(2-methyl-5-nitro-1-imidazolyl)-2-propanol, 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol, 1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitro-imidazole, 1-chloro-3-(2-methyl-5-nitro-imidazol-1-yl)propan-2-ol, Imidazole-1-ethanol, alpha-(chloromethyl)-2-methyl-5-nitro-, SR-01000000256, 3-chloro-1-(2-methyl-5-nitroimidazolyl)propan-2-ol, ornidone, ornilox, ornisid, ornitop, Ornidazole,(S), NCGC00016723-01, Prestwick_584, CAS-16773-42-5, Ro7-0207, Opera_ID_1555, Ornidazole (USAN/INN), Prestwick0_000164, Prestwick1_000164, Prestwick2_000164, Prestwick3_000164, (.+/-.)-Ornidazole, AC1L1EJ4, NCIOpen2_006374, SCHEMBL43039, BSPBio_000027, 5-23-05-00072 (Beilstein Handbook Reference), MLS001424188, ARONIS23874, SPBio_001948, Ornidazole, analytical standard, BPBio1_000031, CHEMBL1449676, DTXSID4045420, CTK8B7883, BBC/159, IPWKIXLWTCNBKN-UHFFFAOYSA-N, MolPort-003-959-102, HMS1568B09, HMS2051D22, HMS2093J22, HMS2095B09, HMS2234L22, HMS3373M17, HMS3393D22, HMS3652C03, HMS3712B09, Pharmakon1600-01505981, BB_SC-04838, BCP12975, BCP13382, HY-B0508, KS-00000XM2, KS-000046IF, ZX-AS004376, Tox21_110582, ANW-58859, BBL005302, HTS028365, MFCD00057960, NSC-95075, NSC759295, s3121, SBB006918, STK629340, AKOS005111039, AKOS015894928, Tox21_110582_1, AB02333, AC-2025, AM86682, API0003694, CCG-101064, CCG-213587, CS-2710, DB13026, MCULE-7000574302, NC00314, NSC-759295, NCGC00018275-02, NCGC00018275-05, AK-60553, AN-14384, AS-12121, CC-33355, CPD000058726, LS-78598, SAM001246873, SC-77073, SBI-0206881.P001, AB0011335, AB1004855, AX8146303, BB0293349, TR-007269, AB00513814, FT-0630433, O0417, ST24027072, ST45053251, D05274, K-5196, AB00383044_14, AB00383044_15, 773O425, A810899, I06-0033, SR-01000000256-3, SR-01000000256-4, BRD-A42759514-001-03-1, BRD-A42759514-001-09-8, Ornidazole,1(3-chloro-2-hydroxypropyl)-2-methyl-5-, .alpha.-(Chlormethyl)-2-methyl-5-nitro-imidazol-1-aethanol, 1-chloranyl-3-(2-methyl-5-nitro-imidazol-1-yl)propan-2-ol, 1-chloro-3-(2-methyl-5-nitro-1N-imidazol-1-yl)propan-2-ol, .alpha.-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol, 1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)-2-propanol #, 1-CHLORO-3-(2-METHYL-5-NITRO-IMIDAZOL-1-YL)-PROPAN-2-OL, (alphaS)-alpha-(Chloromethyl)-2-Methyl-5-Nitro-1H-Imidazole-1-Ethanol, alpha-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol (9CI)

ID: 985

InChIKey: IQDIERHFZVCNRZ-LRCDAWNTSA-N
SMILES: C[C@H]1CC[C@H]2[C@@]([C@@H]3CC[C@@H]4[C@H]([C@@H]3CN2C1)C[C@H]5[C@H]4CC(=O)[C@@H]6[C@@]5(CC[C@@H](C6)O)C)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 442977
synonyms found at PubChem are:
Imperialine, sipeimine, 61825-98-7, UNII-JKN43410XZ, Kashmirine, JKN43410XZ, (3-beta,5-alpha,17-beta)-3,20-Dihydroxycevan-6-one, Cevan-6-one, 3,20-dihydroxy-, (3-beta,5-alpha,17-beta)-, C27H43NO3, Raddeamine, Raddeamine;, Imperialine ,(S), Imperialine (6CI,7CI), AC1L9DS5, CHEMBL1623724, MolPort-007-980-865, HY-N0696, ZINC8214406, AKOS001580849, CS-3729, LS-52877, peiminine, (3beta,5alpha,17beta)-isomer, N2485, V1532, SR-01000805467, Q-100713, SR-01000805467-3, Cevan-6-one,3,20-dihydroxy-, (3beta,5alpha,17beta)-, (3S,4aS,6aS,6bS,8aR,9S,9aS,12S,15aS,15bR,16aS,16bR)-3,9-dihydroxy-9,12,16b-trimethyldocosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinolin-5(1H)-one

ID: 986

InChIKey: IQJZOBSXWBOFSO-UHFFFAOYSA-N
SMILES: CC1=CC(=O)C2=C(C3=C(C=C2O1)OC(CC3)(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 609688
synonyms found at PubChem are:
Isopeucenin, DIHYDROSPATHELIACHROMENE, 5-hydroxy-2,2,8-trimethyl-3,4-dihydropyrano[3,2-g]chromen-6-one, 13475-11-1, Spectrum_000505, SpecPlus_000050, Spectrum2_000346, Spectrum3_000098, Spectrum4_001357, Spectrum5_000293, AC1LD00L, BSPBio_001656, KBioGR_001913, KBioSS_000985, DivK1c_006146, SPBio_000411, SCHEMBL6274812, CHEMBL3039422, CTK8G8481, KBio1_001090, KBio2_000985, KBio2_003553, KBio2_006121, KBio3_000756, CHEBI:108589, IQJZOBSXWBOFSO-UHFFFAOYSA-N, CCG-38621, 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-5-hydroxy-2,2,8-trimethyl-, NCGC00179111-01, 5-Hydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one #

ID: 987

InChIKey: IQPNAANSBPBGFQ-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5280445
synonyms found at PubChem are:
luteolin, 491-70-3, 3',4',5,7-Tetrahydroxyflavone, Luteolol, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Digitoflavone, Luteoline, Flacitran, Weld Lake, Cyanidenon 1470, Salifazide, Yama kariyasu, 5,7,3',4'-Tetrahydroxyflavone, UNII-KUX1ZNC9J2, C.I. Natural Yellow 2, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, 7-Tetrahydroxyflavone, CCRIS 3790, EINECS 207-741-0, KUX1ZNC9J2, CHEMBL151, BRN 0292084, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone, C.I. 75590, FLAVONE, 3',4',5,7-TETRAHYDROXY-, CHEBI:15864, IQPNAANSBPBGFQ-UHFFFAOYSA-N, IN1269, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 3′,4′,5,7-Tetrahydroxyflavone, Q-100551, SMR000326896, SR-01000779333, B-Lactams, 4dew, 4dgn, 4hkn, Luteolin,(S), LU2, Prestwick_122, PubChem18249, AC1NQX1A, Prestwick0_000870, Prestwick1_000870, Prestwick2_000870, Prestwick3_000870, ACMC-209kf3, D01OBV, D04AIT, BIDD:PXR0059, Lopac0_000660, Oprea1_849964, SCHEMBL20426, BSPBio_000919, Luteolin, analytical standard, MLS000697655, MLS000860038, MLS002154043, MLS006011917, BIDD:ER0122, SPBio_002840, BDBM7459, BPBio1_001011, GTPL5215, MEGxp0_000143, DTXSID4074988, ACon1_000223, cid_5280445, CTK8B1741, KS-00000MHI, AOB5669, MolPort-000-706-683, HMS1570N21, HMS2097N21, HMS2220C06, HMS3356L02, HMS3561N09, HMS3649N21, HMS3656A05, HMS3714N21, Luteolin, >=99.0% (TLC), BCP03511, HY-N0162, TNP00073, Luteolin, >=98% (TLC), powder, ANW-30733, BBL027837, BS0245, CL0029, GP5376, LMPK12110006, MFCD00017309, s2320, SBB066117, STK801923, ZINC18185774, AKOS002140588, AC-1125, BCP9000865, CCG-208309, CS-4611, KS-5202, MCULE-6874646775, RTR-017772, SMP2_000042, NCGC00016467-01, NCGC00016467-02, NCGC00016467-03, NCGC00016467-04, NCGC00016467-05, NCGC00016467-06, NCGC00016467-07, NCGC00142375-01, NCGC00142375-02, NCGC00142375-03, NCGC00179375-01, NCGC00179375-02, 4CN-0710, AJ-70437, AK-73099, AN-15217, BC208070, BR-73099, CAS-491-70-3, CJ-15855, LS-69039, SC-17258, ST024703, BCP0726000198, AB0010480, AX8006331, KB-221427, ST2416056, FT-0600053, N1831, T2682, 91L703, C01514, J10229, L 9283, S-1623, S00110, Luteolin, primary pharmaceutical reference standard, I06-0436, SR-01000779333-4, SR-01000779333-5, SR-01000779333-7, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone, BRD-K05236810-001-05-9, 23A002A4-B47B-46CD-848C-65042EACF3FF, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-benzopyrone-4-one, 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one #, 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- (9CI), 1318-21-4

ID: 988

InChIKey: IQPSEEYGBUAQFF-UHFFFAOYSA-N
SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4679
synonyms found at PubChem are:
pantoprazole, 102625-70-7, Protonix, Pantozol, Pantoprazolum, Pantoprazol, Pantoprazole Sodium, BY-1023, Pantoloc, Pantoprazol [INN-Spanish], Pantoprazolum [INN-Latin], SK&F-96022, Controloc Control, Protonix I.V., Protonix IV, Pantoprozole, Astropan, Pantor, SK&F 96022, BY 1023, Pantoprazole Na, Protium, Somac, Pantoprazole [USAN:BAN:INN], C16H15F2N3O4S, Pantozol Control, SK-96022, HSDB 7292, SKF-96022, Pantoprazole (USAN/INN), CHEMBL1502, CHEBI:7915, Pantoprazole sodium hydrate, 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole, 5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole, NCGC00095188-01, Protonix (TN), UNII-SX78SGO2TV, DSSTox_CID_3416, 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, DSSTox_RID_77019, DSSTox_GSID_23416, Panyocid, Zosecta, L-Pantoprazole, apo-Pantoprazole, Somac Control, Pantecta Control, Pantoloc Control, 6-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole, 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole, Pantoprazole sodium sesquihydrate, Pantoprazole, S-, (-)-Pantoprazole, CAS-102625-70-7, SX78SGO2TV, S-(-)-Pantoprazole, Pantoprazole [USAN:INN:BAN], 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, 5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole, Controloc (TN), Astropan (TN), Pantecta (TN), Pantoloc (TN), Pantopan (TN), Pantotab (TN), Pantozol (TN), Ulcepraz (TN), Inipomp (TN), Protium (TN), Pantor (TN), Somac (TN), Pantoprazole (Protonix), Pantoprazole-d6 (Rac), AC1L1IPJ, D0T6XX, EC 600-331-6, SCHEMBL29465, BSPBio_002320, MLS003882559, BIDD:GT0003, SPECTRUM1505818, GTPL7260, DTXSID4023416, CTK8E8734, IQPSEEYGBUAQFF-UHFFFAOYSA-N, MolPort-003-666-752, MolPort-005-933-577, HMS1922H20, HMS2090H03, HMS2093F14, Pharmakon1600-01505818, BCP21400, Tox21_111477, AC-679, BDBM50241342, MFCD00870182, NSC759257, s2105, STL451032, AKOS015894910, Tox21_111477_1, CCG-213558, CS-3161, DB00213, MCULE-8988409059, NSC-759257, 1H-Benzimidazole, 6-(difluoromethoxy)-2-((S)-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, 5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole, NCGC00095188-02, NCGC00095188-03, NCGC00095188-04, NCGC00095188-05, 142678-35-1, AN-15599, BC203892, HY-17507, LS-32883, SMR002533625, SBI-0206873.P001, AB0012612, AB2000509, RT-014935, TL8000127, B4720, FT-0602547, C11806, D05353, W-1227, AB01275513-01, AB01275513_02, 625P707, A800593, SR-01000763715, I06-0068, J-000744, SR-01000763715-3, 5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl), BRD-A22380646-001-01-5, BRD-A22380646-001-02-3, 2-(((3,4-Dimethoxy-2-pyridinyl)methyl)-sulfinyl)-5-methyl-1H-1,3-benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, 5-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole, 5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-3H-1,3-benzodiazole, 5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole, 5-DifluoroMethoxy-2-[(3,4-diMethoxy-2-pyridinyl)Methyl-sulfinyl]-1H-benziMidazole, 5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole, 6-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole, 6-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole, 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole, 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methane]sulfinyl}-1H-1,3-benzodiazole, 6-[bis(fluoranyl)methoxy]-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole, 5-(DIFLUOROMETHOXY)-2-[[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE(Sodium salt form)

ID: 989

InChIKey: IQVQXVFMNOFTMU-FLIBITNWSA-N
SMILES: CCC/C=C\1/C2=C(C=CCC2)C(=O)O1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5319022
synonyms found at PubChem are:
Ligustilide, 4431-01-0, (Z)-Ligustilide, Z-ligustilide, cis-ligustilide, Ligustilide A, (Z)-3-Butylidene-4,5-dihydroisobenzofuran-1(3H)-one, UNII-10HE68JD06, CHEMBL481246, CHEBI:68232, IQVQXVFMNOFTMU-FLIBITNWSA-N, 10HE68JD06, (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one, 1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-, (3Z)-, 3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone, (3Z)-3-butylidene-4,5-dihydroisobenzofuran-1-one, trans-ligustilide, 81944-09-4, 3-butylidene-4,5-dihydrophthalide, Ligustilide, (E)-, AC1NSXKH, Spectrum5_000551, SCHEMBL11967666, Ligustilide, >=98% (HPLC), MolPort-003-665-830, MolPort-044-724-576, BCP09458, HY-N0401, ZINC2386261, BDBM50441016, AKOS006276856, AC-8049, CS-5299, AS-15334, O904, C16987, 3-Butyliden-4,5-dihydro-3H-isobenzofuran-1-one, 431L010, A826540, 1(3H)-Isobenzofuranone,3-butylidene-4,5-dihydro-, Q-100482, 1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-, (Z)-, 1-Ethyl-1-methyl-1,1a,6,7-tetrahydrocyclopropa[c][2]benzofuran-3(3aH)-one, (1E)-2-(4-Chlorophenyl)-3-(4-morpholinyl)-N-[(Z)-4-pyridinylmethylidene]-3-thioxo-1-propen-1-amine

ID: 990

InChIKey: IRHXGOXEBNJUSN-YOXDLBRISA-N
SMILES: CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 60934
synonyms found at PubChem are:
Saquinavir mesylate, 149845-06-7, Invirase, Fortovase, Saquinavir mesilate, Saquinavir, Mesylate, UNII-UHB9Z3841A, Ro 31-8959/003, Saquinavir monomethanesulfonate salt, UHB9Z3841A, CHEBI:32121, Saquinavir mesylate (AIDS Initiative), NCGC00091469-01, Invirase (TN), DSSTox_CID_3835, DSSTox_RID_77202, DSSTox_GSID_23835, (S)-N-((alphaS)-alpha-((1R)-2-((3S,4aS,8aS)-3-(tert-Butylcarbamoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinamide monomethanesulfonate (salt), Ro 31-8959, (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate, (S)-N1-((2S,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-phenylbutan-2-yl)-2-(quinoline-2-carboxamido)succinamide methanesulfonate, Butanediamide, N(sup 1)-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4abeta,8abeta))-, monomethanesulfonate (salt), Butanediamide, N1-((1S,2R)-3-((3S,4aS,8aS)-3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (2S)-, monomethanesulfonate (salt), Saquinavir mesylate [USAN], Saquinavir mesylate [USAN:USP], (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;methanesulfonic acid, N1-{(1S,2R)-1-benzyl-3-[(3S,4aS,8aS)-3-[(tert-butylamino)carbonyl]octahydroisoquinolin-2(1H)-yl]-2-hydroxypropyl}-N2-(quinolin-2-ylcarbonyl)-L-aspartamide methanesulfonate (salt), C38H50N6O5, CAS-149845-06-7, Saquinavir mesilate (JAN), Saquinavir mesylate (USP), AC1L1U6R, SCHEMBL42352, MLS001401395, Saquinavir Monomethanesulfonate, CHEMBL282042, DTXSID9023835, CTK8E9063, AOB1668, IRHXGOXEBNJUSN-YOXDLBRISA-N, MolPort-005-935-781, HMS1571O10, HMS2051D04, HMS2098O10, HMS2231C15, HMS3715O10, 149845-06-7 (mesylate), Tox21_111137, Tox21_202533, 127779-20-8 (Parent), LS-872, MFCD00944907, 127779-20-8 (base), AKOS015962362, AC-1333, CCG-100992, KS-1110, NC00242, NCGC00260082-01, AN-15024, BC680513, CPD000469290, R-56, SAM001246578, SMR000469290, Ro-318959003, RT-015634, Ro-31-8959-003, Ro-31-8959/003, Saquinavir mesylate, >=98% (HPLC), powder, C12560, D01160, W-5240, 845S067, SR-01000763454, J-008634, SR-01000763454-4, Saquinavir mesilate, European Pharmacopoeia (EP) Reference Standard, Saquinavir mesylate, United States Pharmacopeia (USP) Reference Standard, Saquinavir for system suitability, European Pharmacopoeia (EP) Reference Standard, (2S)-N-[(1S,2R)-3-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-1-benzyl-2-hydroxy-propyl]-2-(quinoline-2-carbonylamino)butanediamide; methanesulfonic acid, (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide; methanesulfonic acid, (2S)-N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate, (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide Mesylate, N-t-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)-isoquinoline-3(S)-carboxamide methanesulphonate

ID: 991

InChIKey: IRJCBFDCFXCWGO-UHFFFAOYSA-N
SMILES: C1=C(ONC1=O)C(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 1233
synonyms found at PubChem are:
Ibotenic acid, 2552-55-8, Ibotenate, (+/-)-Ibotenic acid, Amanita muscaria, alpha-Amino-3-hydroxy-5-isoxazoleacetic acid, NSC204850, NSC 204850, alpha-Amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid, 5-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-3-oxo-, CHEBI:5854, CHEMBL284895, 2-amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid, alpha-amino-3-hydroxy-5-isooxazolacetic acid, 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid, 4-Isoxazoline-5-acetic acid, alpha-amino-3-oxo-, C5H6N2O4, DL-Ibotenic acid, (RS)-Ibotenic acid, SR-01000075462, dl-ibotenic acid., (y)-Ibotenic acid, (?)-Ibotenic acid, D01YEN, AC1L1B0Q, Lopac0_000651, MLS002153141, SCHEMBL153359, 4-Isoxazoline-5-acetic acid, .alpha.-amino-3-oxo-, Ibotenic acid, ~95%, solid, GTPL1371, BDBM82355, CTK8G0254, MolPort-003-941-798, MolPort-003-983-596, HMS2230A08, HMS3262C03, HMS3266E19, HMS3369N13, BCP23586, HY-N2311, NSC_1233, Tox21_500651, FCH831700, MFCD00069294, PDSP1_001426, PDSP2_001410, AKOS006228673, AKOS027320609, ACM2552558, CCG-204738, LP00651, NSC-204850, ( inverted question mark)-Ibotenic acid, NCGC00015555-03, NCGC00015555-04, NCGC00015555-05, NCGC00015555-06, NCGC00024524-02, NCGC00024524-03, NCGC00024524-04, NCGC00261336-01, 5-Isoxazoleacetic acid,3-dihydro-3-oxo-, CS-13243, LS-86500, SMR001230640, CAS_2552-55-8, 2-amino-2-(3-oxoisoxazol-5-yl)acetic acid, CS-0020472, EU-0100651, FT-0696850, ST50824671, C10600, I 2765, 2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid, alpha-amino-(3-hydroxy-5-isoxazolyl)acetic acid, Amino(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid, L000672, (+/-)alpha-amino-3-hydroxy-5-isoxazoleacetic acid, 5-Isoxazoleacetic acid,a-amino-2,3-dihydro-3-oxo-, J-016035, SR-01000075462-1, SR-01000075462-3, Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic acid, amino(3-oxo-2,3-dihydro-1,2-oxazol-5-yl)acetic acid, Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Ibotenic acid), ( inverted question mark)-alpha-Amino-3-hydroxy-5-isoxazoleacetic acid, 31758-99-3

ID: 992

InChIKey: IRMJITANSXXVLE-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=NN(C(=O)C2)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MH Nantz" "LJ Galietta" "K By" "AS Verkman" "MJ Kurth" "MF Springsteel" "M Eda" "EJ Niedzinski" "MJ Haddadin"

CID is 12632313
synonyms found at PubChem are:
SCHEMBL4661656, CTK8J5227, IRMJITANSXXVLE-UHFFFAOYSA-N, 59848-47-4, 1-phenyl-3-(p-tolyl)-1H-pyrazol-5(4H)-one, 1-Phenyl-3-(4-methylphenyl)-1H-pyrazole-5(4H)-one, 1-phenyl-3-(4-methylphenyl)-4, 5-dihydropyrazol-5-one

ID: 993

InChIKey: IRSCQMHQWWYFCW-UHFFFAOYSA-N
SMILES: C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3454
synonyms found at PubChem are:
ganciclovir, 82410-32-0, Gancyclovir, Cytovene, Vitrasert, Hydroxyacyclovir, Ganciclovirum, Zirgan, RS-21592, Cymevene, HHEMG, Biolf 62, BW-759U, Ganciclovirum [Latin], 2'-NDG, 2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1H-purin-6(9H)-one, BW 759U, 2'-Nor-2'-deoxyguanosine, BIOLF-62, Citovirax, Cymevan, Cymeven, 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine, Virgan, BW-B 759U, Cytovene-IV, UNII-P9G3CKZ4P5, DRG-0018, Vitrasert (TN), BW 759, Cytovene (TN), 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one, CCRIS 9212, GA2, HSDB 6512, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, 9-((1,3-Dihydroxy-2-propoxy)methyl)guanine, Ganciclovir [USAN:INN:BAN:JAN], IN1478, 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, GCV & MSL, P9G3CKZ4P5, Ganciclovir (JAN/USP/INN), MLS000028481, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, CHEBI:465284, 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, Natclovir, 2-Amino-1,9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6-H-purin-6-one, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one, BW-795, MB3795, ST-605, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, GCV & 1110U81, Cytovene IV, NCGC00015471-02, SMR000058324, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one, CAS-82410-32-0, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one, G 2536, DSSTox_CID_21032, DSSTox_RID_79613, DSSTox_GSID_41032, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol, 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1,9-dihydro-6H-purin-6-one, CPD000058324, SR-01000075894, 9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine, denosine, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-1H-purin-6-one, Ganciclovir,(S), Cymevene (TN), Prestwick_1068, Zirgan (TN), Ganciclovir [USAN:USP:INN:BAN:JAN], Opera_ID_284, Prestwick0_000839, Prestwick1_000839, Prestwick2_000839, Prestwick3_000839, Lopac-G-2536, CHEMBL182, D01LAP, D05ARP, EC 627-054-3, AC1L1FZ2, AC1Q52OB, SCHEMBL3033, Lopac0_000539, BSPBio_000797, ISIS 2922 + Ganciclovir, MLS001077349, BIDD:GT0783, SPBio_002718, BPBio1_000877, ZINC1505, DTXSID8041032, methyl)-1H-purin-6(9H)-one, SCHEMBL14491348, BDBM85707, CTK8A1866, CTK8B5009, KS-00000JPM, Ganciclovir & D5-dgA immunotoxin, IRSCQMHQWWYFCW-UHFFFAOYSA-N, MolPort-000-758-398, MolPort-002-507-301, MolPort-006-167-681, HMS1570H19, HMS2090K08, HMS2097H19, HMS2235C21, HMS3259B13, HMS3261L19, HMS3371H01, HMS3604L19, HMS3655M18, HMS3714H19, Pharmakon1600-01502362, ACT03317, BCP12705, Ganciclovir & C34-dgA immunotoxin, NSC_3454, Tox21_110160, Tox21_500539, ANW-47031, BBL029078, MFCD00870588, NSC759656, PDSP1_000816, PDSP2_000803, s1878, SBB066292, STK801910, AKOS004119898, AKOS026749928, Tox21_110160_1, AC-8069, AN-5258, CCG-204629, CS-2014, DB01004, Ganciclovir, >=99% (HPLC), powder, KS-1065, LP00539, MCULE-9512761592, NC00647, NE60398, NSC-759656, SMP2_000038, NCGC00015471-01, NCGC00015471-03, NCGC00015471-04, NCGC00015471-05, NCGC00015471-06, NCGC00015471-08, NCGC00093928-01, NCGC00093928-02, NCGC00168567-01, NCGC00188980-01, NCGC00261224-01, 9-(1,3-dihydroxy-2propoxymethyl)guanine, AJ-08038, AN-14719, HY-13637, LS-73939, SAM002548936, SAM002589952, SC-12208, ZB000351, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, 107910-75-8 (mono-hydrochloride salt), AB0012496, AB2000347, CAS_82410-32-0, 2-amino-9-((1,3-dihydroxypropan-2-yloxy), 9-(1,3-dihydroxy-2-propoxymethyl)-guanine, EU-0100539, FT-0611007, G0315, EN300-49857, C07019, D00333, J10127, 40034-EP2377510A1, 410G320, A840322, Ganciclovir, Antibiotic for Culture Media Use Only, SR-01000721941, I07-0010, Q-201148, SR-01000075894-1, SR-01000075894-4, SR-01000721941-3, Z1259084907, Ganciclovir, European Pharmacopoeia (EP) Reference Standard, 2-azanyl-9-[1,3-bis(oxidanyl)propan-2-yloxymethyl]-3H-purin-6-one, Ganciclovir, United States Pharmacopeia (USP) Reference Standard, 2-amino-9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}hydropurin-6-one, Ganciclovir, Pharmaceutical Secondary Standard; Certified Reference Material, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-3,9-dihydro-6H-purin-6-one, Ganciclovir, 1.0 mg/mL (1% 1M HCl in Methanol), certified reference material, 106931-35-5, 86357-12-2, 96551-29-0, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)- and MSL, neutralizing monoclonal antibody, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-and MSL, neutralizing monoclonal antibody

ID: 994

InChIKey: IRSFLDGTOHBADP-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 3218
synonyms found at PubChem are:
EMBELIN, 550-24-3, Embelic acid, Emberine, 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, 2,5-Dihydroxy-3-undecyl-1,4-benzoquinone, 2,5-Dihydroxy-3-undecyl-p-benzoquinone, 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione, UNII-SHC6U8F5ER, CHEBI:4778, Embelin, Embelia ribes, C17H26O4, NSC91874, XIAP inhibitor, Embelin, EINECS 208-979-8, NSC 91874, SHC6U8F5ER, BRN 1885786, Apoptosis Activator III, Embelin, p-Benzoquinone, 2,5-dihydroxy-3-undecyl-, SR-01000597536, Spectrum_001513, Tocris-2156, 2,5-dihydroxy-3-undecyl-1,4-benzochinon, SpecPlus_000501, AC1L1FFT, AC1Q6BUE, Spectrum3_001931, Spectrum4_001760, Spectrum5_000620, D05HSW, BSPBio_003531, KBioGR_002240, KBioSS_001993, 4-08-00-02769 (Beilstein Handbook Reference), MLS000563189, BIDD:ER0529, DivK1c_006597, SCHEMBL148744, SPECTRUM1504074, CHEMBL221137, KBio1_001541, KBio2_001993, KBio2_004561, KBio2_007129, KBio3_002783, DTXSID80203537, IRSFLDGTOHBADP-UHFFFAOYSA-N, MolPort-000-165-323, HMS1922B07, HMS2271A03, HMS3268N13, HMS3652J16, TNP00137, ZINC1531764, BDBM50078850, BS0074, CCG-39906, Embelin, >=98% (HPLC), powder, HSCI1_000123, MFCD00016369, NSC-91874, SBB005949, AKOS016010144, CS-1879, MCULE-1558476181, p-Benzoquinone,5-dihydroxy-3-undecyl-, SDCCGMLS-0066817.P001, 2,4-dione, 2,5-dihydroxy-3-undecyl-, NCGC00017248-01, NCGC00017248-02, NCGC00017248-03, NCGC00017248-04, NCGC00017248-05, NCGC00017248-06, NCGC00017248-07, NCGC00017248-08, NCGC00017248-10, NCGC00025359-01, NCGC00025359-02, NCGC00025359-03, NCGC00025359-04, NCGC00025359-05, AK115155, HY-17473, LS-40347, NCI60_042031, SMR000470851, ST057212, KB-225927, 2,5-Dihydroxy-3-undecyl-[1,4]benzoquinone, 4CH-024635, FT-0712499, S7025, ST24038748, V0365, C10342, C-52730, SR-01000597536-1, SR-01000597536-3, 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl-, 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl- (9CI), NCGC00017248-12!2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione

ID: 995

InChIKey: IRVWPZRYDQROLU-ZDUSSCGKSA-N
SMILES: COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)O)N)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 453131
synonyms found at PubChem are:
TRIMETHYLCOLCHICINIC ACID, N-Deacetylcolchiceine, 3482-37-9, N-Deacetyl Colchiceine, UNII-333BVY614O, Desacetylcolchiceine, NSC 36796, MLS002153887, 333BVY614O, SKF 284, SMR000112547, (7S)-7-amino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one, EINECS 222-464-5, BRN 3008992, NSC36796, AC1L9QRS, Prestwick3_000580, BSPBio_000400, 4-14-00-00937 (Beilstein Handbook Reference), BPBio1_000440, CHEMBL517186, cid_453131, BDBM79208, CTK8G1719, (S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxybenzo(a)heptalen-9(5H)-one, Colchiceine, N-deacetyl- (8CI), HMS2096D22, HMS2268E20, ZINC19632731, AKOS015969698, ACM3482379, NCGC00179572-01, Colchiceine, N-deacetyl- (VAN) (8CI), AB00513865, FT-0665494, BRD-K84300594-001-02-6, (7S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-benzo[a]heptalen-9(5H)-one, (7S)-7-azanyl-1,2,3-trimethoxy-10-oxidanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one, Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-10-hydroxy -1,2,3-trimethoxy-, (7S)-, Benzo(a)heptalen-9(5H)-one, 7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (S)- (9CI)

ID: 996

InChIKey: IRYJRGCIQBGHIV-UHFFFAOYSA-N
SMILES: CC1(C(=O)N(C(=O)O1)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 5576
synonyms found at PubChem are:
trimethadione, Tridione, Troxidone, 127-48-0, Trimetadione, Trimethadion, Trimetin, Absentol, Convenixa, Convexina, Epidione, Petidion, Petimalin, Tioxanona, Tridilona, Trimedal, Trimethin, Trioxanona, Absetil, Epixal, Petidon, Petilep, Ptimal, Tridion, Edion, Minoaleviatin, Trimethdione, Trimethinum, Minoaleuiatin, Trimethadionum, Tredione, Tricione, Trilidona, Trimedone, Trioksal, Triozanona, Tromedone, Epidone, Etydion, Pitmal, Tridone, 3,5,5-Trimethyloxazolidine-2,4-dione, Trimetadiona, Trimetadione [DCIT], Mino-Aleviatin, Neo-Absentol, Trimetadiona [INN-Spanish], Trimethadionum [INN-Latin], 2,4-OXAZOLIDINEDIONE, 3,5,5-TRIMETHYL-, 3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione, A 2297, 3,5,5-Trimethyl-2,4-oxazolidinedione, 3,3,5-Trimethyl-2,4-diketooxazolidine, Trimethadione [INN:JAN], UNII-R7GV3H6FQ4, NSC 15799, Tridione (TN), 3,5,5-Trojmetylooksazolidyno-2,4-dion, EINECS 204-845-8, 3,5,5-Trojmetylooksazolidyno-2,4-dion [Polish], BRN 0121627, R7GV3H6FQ4, 3,5,5,-Trimethyloxazolidine-2,4-dione, C6H9NO3, 3,5,5-TRIMETHYL-OXAZOLIDINE-2,4-DIONE, trimethyl-1,3-oxazolidine-2,4-dione, NCGC00016383-01, CAS-127-48-0, DSSTox_CID_1396, 2, 3,5,5-trimethyl-, DSSTox_RID_76137, DSSTox_GSID_21396, 3,5-Trimethyl-2,4-oxazolidinedione, 3,5-Trimethyl-2,4-diketooxazolidine, WLN: T5OVNV EHJ C1 E1 E1, Mino aleviatin, Tridione Dulcet, Trimethadione [USP:INN:BAN:JAN], Prestwick_815, 3,5,5-trimethyl-2,4-dioxooxazolidine, ACMC-1BYOW, AC1L1KNK, AC1Q3XZF, Prestwick0_000515, Prestwick1_000515, Prestwick2_000515, Prestwick3_000515, CHEMBL695, D0U4VT, Trimethadione (JP15/INN), Trimethadione (JP17/INN), SCHEMBL28882, BSPBio_000469, Abbott Brand of Trimethadione, MLS001076685, SPBio_002390, BPBio1_000517, CHEBI:9727, GTPL7316, DTXSID9021396, CTK7H6925, IRYJRGCIQBGHIV-UHFFFAOYSA-, IRYJRGCIQBGHIV-UHFFFAOYSA-N, MolPort-001-846-840, HMS1569H11, HMS2093D10, HMS2096H11, HMS2235E12, HMS3713H11, Pharmakon1600-01505466, HY-A0092, KS-00001F5Z, NSC15799, ZINC1530710, Tox21_110408, Tox21_200231, FCH917493, NSC-15799, NSC169503, NSC759152, Trimethadione 1.0 mg/ml in Methanol, AKOS006229172, CCG-213460, DB00347, LS-7736, MCULE-4761457520, NSC-169503, NSC-759152, 3,5,5-Trimethyl oxazolidine-2,4-dione, NCGC00016383-02, NCGC00016383-03, NCGC00016383-05, NCGC00257785-01, CJ-24008, KB-28442, SMR000499583, SBI-0206923.P001, TC-169983, FT-0694585, ST50411784, D00392, 20503-EP2275420A1, 20503-EP2280008A2, 20503-EP2298764A1, 20503-EP2298765A1, 20503-EP2308867A2, 20503-EP2308870A2, 20503-EP2314585A1, 3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione #, C-52877, SR-01000763540, J-005496, SR-01000763540-2, BRD-K16606819-001-07-7, I14-44647, 3,5,5,-Trimethyloxazolidine-2,4-dione, analytical standard, Trimethadione, European Pharmacopoeia (EP) Reference Standard, InChI=1/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3, Trimethadione, United States Pharmacopeia (USP) Reference Standard

ID: 997

InChIKey: ISEUFVQQFVOBCY-UHFFFAOYSA-N
SMILES: CC(C)NC1=NC(=NC(=N1)OC)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4928
synonyms found at PubChem are:
prometon, Gesafram, Pramitol, Methoxypropazine, 1610-18-0, PROMETONE, Ontrack, Pramitol 5P, Ontrack-we-2, Primatol 25e, Gesafram 50, 2-Methoxy-4,6-bis(isopropylamino)-s-triazine, Ontracic 800, 2,4-Prometone, 2,4-Bis(isopropylamino)-6-methoxy-s-triazine, 4,6-Bis(isopropylamino)-2-methoxy-s-triazine, Caswell No. 096, 2,4-Bis(isopropylamino)-6-methoxy-1,3,5-triazine, 2,6-Diisopropylamino-4-methoxytriazine, N,N'-Diisopropyl-6-methoxy-1,3,5-triazine-2,4-diamine, Prometone [ISO-French], 2-Methoxy-4,6-bis(isopropylamino)-1,3,5-triazine, UNII-DY7SQ0399L, Prometon [ANSI:BSI:ISO], NSC 163048, N,N'-Diisopropyl-6-methoxy-1,3,5-triazine-2,4-diyldiamine, G-31435, HSDB 1519, EINECS 216-548-0, s-Triazine, 2,4-bis(isopropylamino)-6-methoxy-, EPA Pesticide Chemical Code 080804, 1,3,5-Triazine-2,4-diamine, 6-methoxy-N,N'-bis(1-methylethyl)-, 6-Methoxy-N,N'-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine, BRN 0613574, AI3-60364, DY7SQ0399L, CHEBI:34934, ISEUFVQQFVOBCY-UHFFFAOYSA-N, 2,4-Bis-(isopropylamino)-6-methoxy-1,3,5-triazine, N2,N4-Di-isopropyl-6-methoxy-1,3,5-triazine-2,4-diamine, 1,3,5-Triazine-2,4-diamine, 6-methoxy-N2,N4-bis(1-methylethyl)-, DSSTox_CID_2341, DSSTox_RID_76553, DSSTox_GSID_22341, N2,N4-Diisopropyl-6-methoxy-1,3,5-triazine-2,4-diamine, prometrone, 6-methoxy-N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, 6-methoxy-2-N,4-N-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, CAS-1610-18-0, Spectrum_001831, SpecPlus_000432, Spectrum2_001884, Spectrum3_000826, Spectrum4_000666, Spectrum5_001964, Cambridge id 5353763, Oprea1_311967, SCHEMBL22999, BSPBio_002351, KBioGR_001071, KBioSS_002336, Prometon, analytical standard, SPECTRUM330034, 2-Methoxy-4,3,5-triazine, MLS000532451, BIDD:ER0384, DivK1c_006528, SPBio_001788, AC1L1J94, AC1Q57S0, CHEMBL1486524, DTXSID6022341, CTK8E3502, KBio1_001472, KBio2_002333, KBio2_004901, KBio2_007469, KBio3_001851, MolPort-002-114-166, HMS2166M10, HMS3309N13, ZINC246221, Tox21_202098, Tox21_300893, CCG-39422, NSC163048, Prometon 10 microg/mL in Cyclohexane, AKOS022181473, AC01011, MCULE-9719565564, NSC-163048, Prometon 10 microg/mL in Acetonitrile, NCGC00094528-01, NCGC00094528-02, NCGC00094528-03, NCGC00094528-04, NCGC00094528-05, NCGC00094528-06, NCGC00094528-07, NCGC00254797-01, NCGC00259647-01, AJ-18322, SMR000137402, ZB009779, 2-Methoxy-4,6-bis(isopropylamino)triazine, LS-155137, TR-006850, FT-0718227, Prometon, PESTANAL(R), analytical standard, s-Triazine,4-bis(isopropylamino)-6-methoxy-, C14186, WLN: T6N CN ENJ BO1 DMY1&1 FMY1&1, AB00053028-02, C-52941, J-009774, BRD-K99029477-001-02-6, 1,5-Triazine-2,4-diamine, 6-methoxy-N,N'-bis(1-methylethyl)-, 11126-75-3

ID: 998

InChIKey: ISRUGXGCCGIOQO-UHFFFAOYSA-N
SMILES: CC(C)OC1=CC=CC=C1OC(=O)NC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 4944
synonyms found at PubChem are:
propoxur, Baygon, 114-26-1, 2-Isopropoxyphenyl methylcarbamate, Aprocarb, Propoxure, Sendran, Propoxylor, Blattanex, Blattosep, Mrowkozol, Propotox, Suncide, Bolfo, Boruho, Brygou, Dalf dust, Invisi-Gard, 2-Isopropoxyphenyl N-methylcarbamate, Arprocarb, Isocarb, Propyon, Rhoden, Bifex, Boruho 50, IPMC, o-Impc, Tugon fliegenkugel, Unden (Pesticide), Bayer B 5122, Bayer 39007, Propoksuru, Chemagro 9010, Unden 50PM, PHC 7, PHC (carbamate), Phenol, 2-(1-methylethoxy)-, methylcarbamate, Propoksuru [Polish], Bay 9010, Caswell No. 508, ENT 25,671, 2-(1-Methylethoxy)phenol methylcarbamate, O-(2-Isopropoxyphenyl) N-methylcarbamate, BAY 5122, o-Isopropoxyphenyl N-methylcarbamate, UNII-BFH029TL73, BAY 39007, Propoxur [BAN], NSC 379584, Phenol, o-isopropoxy-, methylcarbamate, CCRIS 1392, HSDB 603, OMS-33, CHEBI:34938, o-Isopropoxyphenyl methylcarbamate, 2-Isopropoxyphenyl-N-methylcarbamat, EINECS 204-043-8, Carbamic acid, methyl-, o-isopropoxyphenyl ester, EPA Pesticide Chemical Code 047802, BRN 1879891, AI3-25671, BFH029TL73, OMS 33, (2-propan-2-yloxyphenyl) N-methylcarbamate, 2-Isopropoxyphenyl-N-methylcarbamat [German], ISRUGXGCCGIOQO-UHFFFAOYSA-N, Propoxur (BAN), 2-(1-methylethoxy)phenyl methylcarbamate, 2-(propan-2-yloxy)phenyl methylcarbamate, 2-(1-Methylethoxy)phenyl N-methylcarbamate, DSSTox_CID_1948, 2-[(1-methylethyl)oxy]phenyl methylcarbamate, DSSTox_RID_76421, DSSTox_GSID_21948, Propoxur (baygon), CAS-114-26-1, Propoxur [INN:BAN], Pillargon, Propogon, Boygon, Baygon G, Baygon®, Bolfo (TN), Spectrum_001923, SpecPlus_000554, Spectrum2_001232, Spectrum3_000857, Spectrum4_000697, Spectrum5_002032, 2-(propan-2-yloxy)phenyl methyl(14c)carbamate, AC1L1JA0, AC1Q1QR6, SCHEMBL27794, BSPBio_002473, KBioGR_001193, KBioSS_002465, SPECTRUM330066, MLS002207242, BIDD:ER0307, DivK1c_006650, SPBio_001104, Isopropoxyphenyl methylcarbamate, AC1Q61S0, CHEMBL446060, 2-Isopropoxyphenylmethylcarbamate, DTXSID7021948, CTK8G2609, ISRUGXGCCGIOQO-UHFFFAOYSA-, KBio1_001594, KBio2_002458, KBio2_005026, KBio2_007594, KBio3_001973, MolPort-003-665-461, HMS3264G19, Pharmakon1600-00330066, HY-B0916, ZINC1590885, N-Methyl-2-isopropoxyphenylcarbamate, Tox21_201968, Tox21_301207, BDBM50064617, CCG-39115, NSC379584, NSC755890, Propoxur 10 microg/mL in Cyclohexane, AKOS015889907, (2-isopropoxyphenyl) N-methylcarbamate, NSC-379584, NSC-755890, KS-00001F97, NCGC00094544-01, NCGC00094544-02, NCGC00094544-03, NCGC00094544-04, NCGC00094544-05, NCGC00094544-06, NCGC00094544-07, NCGC00255104-01, NCGC00259517-01, AJ-27685, AN-22735, AS-50078, CC-33975, CJ-25442, LS-50228, S257, SMR000778062, 2-(1-Methylethoxy)phenyl methyl carbamate, SBI-0052551.P002, AX8017616, KB-231050, FT-0603314, Propoxur, PESTANAL(R), analytical standard, C14334, D08442, 2-(1-Methylethoxy)phenol 1-(N-Methylcarbamate), AB00053059_04, 114P261, C-10727, SR-01000872751, I01-4383, J-003071, SR-01000872751-1, Phenol, 2-(1-methylethoxy)-, 1-(N-methylcarbamate), Carbamic acid, methyl-, 2-(1-methylethoxy)phenyl ester, InChI=1/C11H15NO3/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3/h4-8H,1-3H3,(H,12,13)

ID: 999

InChIKey: ISWRGOKTTBVCFA-UHFFFAOYSA-N
SMILES: CC1=CN(C(=O)C=C1)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 40632
synonyms found at PubChem are:
PIRFENIDONE, 53179-13-8, 5-methyl-1-phenylpyridin-2(1H)-one, Esbriet, Deskar, Pirespa, AMR-69, 5-Methyl-1-phenyl-2-(1H)-pyridone, Pirfenidonum, Pirfenidona, AMR 69, 5-Methyl-1-phenyl-1H-pyridin-2-one, 5-methyl-1-phenyl-2(1H)-pyridinone, 2(1H)-Pyridinone, 5-methyl-1-phenyl-, Pirfenidone [USAN:INN], Pirfenidonum [INN-Latin], Pirfenidona [INN-Spanish], 5-methyl-1-phenyl-2-pyridinone, UNII-D7NLD2JX7U, 5-Methyl-1-phenyl-2(1H)-pyridone, Pirfenidone (Deskar), 5-methyl-1-phenylpyridin-2-one, D7NLD2JX7U, BRN 1526549, Pirfenidone (JAN/USAN/INN), 5-Methyl-1-phenyl-2-pyridone, CHEBI:32016, 5-methyl-1-phenyl-pyridin-2-one, ISWRGOKTTBVCFA-UHFFFAOYSA-N, KS-5041, 2(1H)-Pyridone, 5-methyl-1-phenyl-, NCGC00015806-03, 5-METHYL-N-PHENYL-2-1H-PYRIDONE, F-647, P 2116, S-7701, DSSTox_CID_25183, DSSTox_RID_80731, DSSTox_GSID_45183, CAS-53179-13-8, SR-01000076061, glaspia, Prfendone, Pirfenidone D5, Esbriet (TN), PERFENIDONE, Pirfenidone(AMR69), Tocris-1093, Lopac-P-2116, ACMC-209t1g, D02WCI, SCHEMBL4708, AMR69, Lopac0_000907, 5-21-07-00197 (Beilstein Handbook Reference), MLS000860042, GTPL7532, ZINC1958, CHEMBL1256391, DTXSID4045183, 1-phenyl-5-methyl-2-pyridinone, CTK8B3176, HSDB 8340, Pirfenidone, >=97% (HPLC), MolPort-003-666-737, Bio1_000397, Bio1_000886, Bio1_001375, HMS2234G24, HMS3262F16, HMS3267I06, HMS3372A08, HMS3651P08, AC1L2454, AOB31717, BCP04473, EBD52457, HY-B0673, Tox21 110225, Tox21_110225, Tox21_500907, ANW-41906, BDBM50005201, BN0421, CP0088, FCH842465, GP4948, MFCD00866047, NSC748456, s2907, AKOS006273697, Tox21_110225_1, AB07515, AC-6797, AM84939, AN-5207, API0003873, CCG-204989, CS-2905, DB04951, LP00907, NSC-748456, RP24541, RTR-018809, 5-methyl-1-phenyl-2-(1H)-pyridinone;, NCGC00015806-01, NCGC00015806-02, NCGC00015806-04, NCGC00015806-05, NCGC00015806-06, NCGC00024992-01, NCGC00024992-02, NCGC00024992-03, NCGC00261592-01, AJ-08117, AK-72929, BC678265, BR-72929, CC-33825, EN000704, H960, SC-17366, SMR000326900, ZB000448, AB0006721, AX8028958, KB-246459, LS-133834, ST2418816, 4CH-013041, B2288, EU-0100907, FT-0082541, FT-0602686, P1871, D01583, J90039, M-2515, 179P138, A829431, C-07370, I01-1466, J-523979, SR-01000076061-1, SR-01000076061-3, 5-METHYL-1-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE, BRD-K96862998-001-03-1, BRD-K96862998-001-09-8, Pirfenidone, European Pharmacopoeia (EP) Reference Standard

ID: 1000

InChIKey: ITPDYQOUSLNIHG-UHFFFAOYSA-N
SMILES: CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"DY Thomas" "JW Hanrahan" "J Liao" "E Matthes" "SD Macknight" "D Rotin" "R Robert" "GW Carlile" "J Goepp" "B Kus"

CID is 29770
synonyms found at PubChem are:
Ritmocardyl, Rythmarone, Angoron, Atlansil, Cordarex, Miodrone, Pacerone, Renodoron, Trangorex, L 3428 labaz, HSDB 6525, SKF 33134 A, EINECS 243-293-2, NSC 85442, 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone hydrochloride, 2-Butyl-3-benzofuryl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone hydrochloride, Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl, hydrochloride, AC1L1I4H, C25H29I2NO3.HCl, CTK8F7722, MolPort-000-703-416, MCULE-1243290270, LS-87089, 2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl-diethylazanium chloride, Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-, hydrochloride, Amiodarone hydrochloride, Amiodarone HCL, 19774-82-4, Nexterone, Amiodar, Amiodarone (hydrochloride), Amiodaronum hydrochloride, UNII-976728SY6Z, 51087 N HCl, (2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone hydrochloride, MLS000028520, 976728SY6Z, CPD000058296, SMR000058296, Cordarone (TN), DSSTox_CID_17185, DSSTox_RID_79304, DSSTox_GSID_37185, {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine hydrochloride, 2-Butyl-3-benzofuranyl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodo-phenyl]-methanone hydrochloride, SR-01000003087, NCGC00015096-12, CAS-19774-82-4, Ancaron, Amio-Aqueous, (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone;hydrochloride, Prestwick_707, Amiodarone hydrochloride [USP:JAN], Ancaron (TN), Opera_ID_568, AC1L9AZ7, C25H30ClI2NO3, SCHEMBL41348, MLS001076313, MLS001424272, MLS002222247, SPECTRUM2300165, Amiodarone hydrochloride [JAN], CHEBI:2664, CHEMBL1083993, DTXSID7037185, BBC/822, calcium channel (L type) blocker, MolPort-002-915-715, HMS1569A20, Pharmakon1600-02300165, ACT02681, BCP13645, NSC85442, ZX-AS005021, Ketone,5-diiodophenyl, hydrochloride, Tox21_113478, Tox21_300395, Tox21_500122, AC-078, BG0032, CCG-39607, MFCD00069204, NSC-85442, NSC759560, PM-101, s1979, SK&F-33134-A, AKOS015844018, Amiodarone hydrochloride (JP17/USAN), AN-6656, API0001454, CS-1371, KS-5249, LP00122, NC00423, NSC-759560, NCGC00093613-01, NCGC00093613-02, NCGC00093613-03, NCGC00093613-04, NCGC00254295-01, NCGC00260807-01, BC207085, CC-24084, HY-14188, Methanone,5-diiodophenyl]-, hydrochloride, SAM001246646, AB0012080, TL8001651, EU-0100122, FT-0083531, FT-0622300, A 8423, D00636, W-5062, 774A824, Q-200626, SR-01000003087-2, SR-01000003087-8, WLN: T56 BOJ C4 DVR CI EI DO2N2&2 &GH, Z2210825534, Amiodarone Hydrochloride 1.0 mg/ml in Methanol (as free base), 2-Butyl-3-benzofuranyl 4-[(2-diethylamino)ethoxy] 3,5-diiodophenyl ketone, hydrochloride, (2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone hydrochloride, (2-Butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone hydrochloride (1:1), (2-butylbenzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodo-phenyl]methanone hydrochloride, Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-, hydrochloride (9CI), AC1LCW5V, AKOS026750123, FT-0651477, (2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone; hydron; chloride