CandActCFTR Seed Compounds

The following 3114 structures with currently 268914 synonyms are a list compounds which have been reported in 111 CFTR related publications published in the past decade. We collected all structures regardless of an activation of CFTR function or an improvement of CFTR processing, thus also including reported negative compound references or even inhibitors.

ID: 1

InChIKey: TZBJGXHYKVUXJN-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment several

reference list:

"MD Amaral" "Z Cai" "DN Sheppard" "F Mendes" "A Schmidt" "LK Hughes" "H Li"

"S Waldegger" "A Bachmann" "U Russ" "U Quast"

"M Giampieri" "M Mazzei" "M Zacchigna" "P Fossa" "F Cateni" "LJ Galietta" "MT Mazzei" "N Pedemonte"

"JP Clancy" "K Varga" "J Fortenberry" "LC Pyle" "J Collawn" "M Mazur" "EJ Sorscher" "A Jurkevante" "SM Rowe" "B Woodworth" "L Fan" "PA Sloane" "J Fulton" "Y Li"

"H Dang" "R Schlegel" "X Liu" "C Cho" "SE Boyles" "C Cheluvaraju" "NL Quinney" "M Gentzsch" "SH Randell" "IG Chaudhry"

"YJ Chen" "GE Rottinghaus" "LL Clarke" "K Cooper" "LJ Rubin" "L Al-Nakkash"

"KL Hamilton" "MJ Baker"

"TC Hwang" "T Ai" "X Wang" "SG Bompadre" "S Hu" "M Li"

"TC Hwang" "Y Sohma" "YC Yu"

"F Becq" "C Folli" "L Romio" "JM Vierfond" "Y Mettey" "O Zegarra-Moran" "P Fanen" "G Cabrini" "E Caci" "LJ Galietta"

"A Nigg" "K Schoonderwoerd" "HR de Jonge" "MJ Bijvelds" "AB Houtsmuller" "BC Tilly" "CH Lim"

"G Li" "KL Kirk" "K Bernard" "W Wang"

"AD Floyd" "PL Zeitlin" "E Kwon" "M Lim" "K McKenzie"

"DW Vermeer" "AL Berger" "MJ Welsh" "LS Ostedgaard" "PH Karp" "CO Randak"

"H Miki" "A Hanyuda" "TC Hwang" "Y Nakamura" "Y Abe" "SG Bompadre" "Y Sohma" "K Tanaka" "M Yasui" "Y Matsuzaki" "YC Yu"

"D Cao" "S Hadida" "M Miller" "A Hazlewood" "F Van Goor" "T Neuberger" "E Olson" "J Rader" "JH Stack" "T Knapp" "LR Makings" "J González" "J Joubran" "KS Straley" "R Tung" "A Singh" "PD Grootenhuis" "P Negulescu" "V Panchenko"

"MJ Kurth" "MF Springsteel" "MH Nantz" "L Al-Nakkash"

"SM Rowe" "BA Woodworth" "SB Hicks" "D Skinner" "BT Conger" "S Zhang" "EJ Sorscher"

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"F Becq" "S Noël" "C Rogier" "L Dannhoffer" "H DeJonge" "Y Mettey" "PO Strale" "M Wilke"

"O Moran" "O Zegarra-Moran"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

"Z Servetnyk" "C Andersson" "GM Roomans"

"R Melani" "O Zegarra-Moran" "LJ Galietta" "V Tomati"

"KL Hamilton" "PC Chao"

"G Berkers" "JF Dekkers" "CK van der Ent" "JM Beekman" "HR de Jonge" "I Bronsveld" "HM Janssens" "P Van Mourik" "AM Vonk" "KM de Winter-de Groot" "E Kruisselbrink"

"F Becq" "L Froux" "E Sage" "C Coraux"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"L Maiuri" "M Piacentini" "A Tosco" "V Raia" "VR Villella" "G Kroemer"

"I Dey" "K Shah" "NA Bradbury"

"RC Rubenstein" "M Carattino" "L Suaud" "TR Kleyman"

CID is 5280961
synonyms found at PubChem are:
genistein, 446-72-0, Prunetol, Genisteol, 4',5,7-Trihydroxyisoflavone, Genisterin, Sophoricol, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Bonistein, Genestein, Differenol A, NPI 031L, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75610, SIPI 807-1, 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, UNII-DH2M523P0H, NSC 36586, 4,5,7-Trihydroxyiso-flavone, Lactoferrin-genistein, CCRIS 7675, 4',5, 7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, NSC36586, CHEMBL44, EINECS 207-174-9, IN1327, BRN 0263823, PTI G4660 (Genistein), ISOFLAVONE, 4',5,7-TRIHYDROXY-, MLS000738127, DH2M523P0H, STO514, CHEBI:28088, PTI-G4660, SIPI-9764-I, TZBJGXHYKVUXJN-UHFFFAOYSA-N, 4′,5,7-Trihydroxyisoflavone, TNP00151, NSC-36586, GENISTEIN (ENDOCRINE DISRUPTER), GEN, NCGC00015479-09, DSSTox_CID_2308, G 6649, G10000, DSSTox_RID_76542, DSSTox_GSID_22308, ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)), CAS-446-72-0, SR-01000075498, HSDB 7475, PTI G4660, 3kgt, 3kgu, 4&prime, Genistein, 8, Genistein,(S), PTI-G 4660, Genistein (flavonoid), PubChem9852, Spectrum_000320, Tocris-1110, 1x7r, 2qa8, Genistein 85% HPLC, SpecPlus_000305, AC1NQXT4, Spectrum2_000638, Spectrum3_000678, Spectrum4_001543, Spectrum5_000106, Lopac-G-6649, 4',7-Trihydroxyisoflavone, D0L4FS, MolMap_000022, UPCMLD-DP096, 4,5,7-Trihydroxyisoflavone, 4,6,7-Trihydroxyisoflavone, Isoflavone,5,7-trihydroxy-, Lopac0_000520, Oprea1_224620, Oprea1_437815, SCHEMBL19166, BSPBio_002375, KBioGR_002006, KBioGR_002564, KBioSS_000800, KBioSS_002573, SPECTRUM210296, 5-18-04-00594 (Beilstein Handbook Reference), BIDD:ER0113, DivK1c_006401, Genistein, analytical standard, SPBio_000636, 4',5,7-Trihydroxy isoflavone, 4',5,7-trihydroxy-Isoflavone, GTPL2826, MEGxp0_000568, 4,5,7-Trihydroxy Iso-Flavone, DTXSID5022308, UPCMLD-DP096:001, ACon1_001065, BDBM19459, cid_5280961, KBio1_001345, KBio2_000800, KBio2_002564, KBio2_003368, KBio2_005132, KBio2_005936, KBio2_007700, KBio3_001595, KBio3_003042, AOB5073, CHEBI: 28088, cMAP_000086, MolPort-000-003-911, Bio1_000445, Bio1_000934, Bio1_001423, HMS2271K09, HMS3261H21, HMS3267K14, HMS3428M01, HMS3649B22, HMS3654D17, ACT05962, ALBB-015886, BCP07581, KS-00000MH8, Prunetol solution, 20 mM in DMSO, Tox21_110161, Tox21_201428, Tox21_300585, Tox21_500520, AC-472, BBL010484, CCG-38551, CG-009, Genistein solution, 20 mM in DMSO, LMPK12050218, MFCD00016952, s1342, SBB066115, STK801619, ZINC18825330, AKOS001590147, Tox21_110161_1, CS-1534, DB01645, KS-5128, LP00520, LS-1266, MCULE-4857649752, RL03694, RP29616, SMP1_000133, Genistein; 4',5,7-Trihydroxyisoflavone, NCGC00015479-01, NCGC00015479-02, NCGC00015479-04, NCGC00015479-05, NCGC00015479-06, NCGC00015479-07, NCGC00015479-08, NCGC00015479-10, NCGC00015479-11, NCGC00015479-12, NCGC00015479-13, NCGC00015479-14, NCGC00015479-15, NCGC00015479-16, NCGC00015479-17, NCGC00015479-18, NCGC00015479-19, NCGC00015479-20, NCGC00025005-01, NCGC00025005-02, NCGC00025005-03, NCGC00025005-04, NCGC00025005-05, NCGC00025005-06, NCGC00025005-07, NCGC00169711-01, NCGC00169711-02, NCGC00254275-01, NCGC00258979-01, NCGC00261205-01, 690224-00-1, AJ-70669, AN-15821, BC200563, HY-14596, KB-52241, NCI60_003369, SC-04581, SMR000112580, ST056352, AB1004490, EU-0100520, FT-0603395, G0272, N1861, Genistein, disposable screening library format, 46G720, C06563, G-2535, Genistein, synthetic, >=98% (HPLC), powder, J10015, K00046, S-7751, US8552057, 2, AB00052696_09, AB00052696_12, A826657, Genistein, primary pharmaceutical reference standard, I06-0431, Q-100484, SR-01000075498-1, SR-01000075498-3, SR-01000075498-6, 3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone, BRD-K43797669-001-02-3, BRD-K43797669-001-03-1, BRD-K43797669-001-10-6, Genistein, from Glycine max (soybean), ~98% (HPLC), SR-01000075498-10, 5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one, F0001-2388, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)-, UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N, Genistein, United States Pharmacopeia (USP) Reference Standard, Genistein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

ID: 2

InChIKey: VFLDPWHFBUODDF-FCXRPNKRSA-N
SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function likely enhances CFTR function
Order of interaction unknown
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"R Narlawar" "KL Kirk" "K Bernard" "B Schmidt" "W Wang"

"A Dragomir" "GM Roomans" "J Björstad" "L Hjelte"

"K Nakamura" "MA Suico" "H Kai" "T Shuto" "T Okiyoneda" "K Harada" "Y Hashimoto" "K Oyokawa"

"L Qian" "AS Verkman" "Y Song" "D Salinas" "LJ Galietta" "N Pedemonte" "ND Sonawane"

"F Becq" "J Lipecka" "C Norez" "G Planelles" "N Davezac" "N Bensalem" "M Baudouin-Legros" "A Edelman"

"G Wang"

"Y Chen" "ZW Dong" "YC Ruan" "LL Tsang" "HC Chan" "YZ Peng" "T Zhou" "J Chen"

"MJ Caplan" "K Du" "J Glöckner-Pagel" "S Canny" "D Rubin" "V Rajendran" "M Pearson" "SA Weiner" "ME Egan" "GL Lukacs"

"AM Van Heeckeren" "ML Drumm" "RC Boucher" "JR Riordan" "A Mengos" "M Gentzsch" "MR Knowles" "SH Randell" "SE Gabriel" "BR Grubb"

"MJ Caplan" "C Caputo" "MS Cartiera" "WM Saltzman" "EC Ferreira" "ME Egan"

"JS Hong" "KL Kirk" "A Rab" "W Wang" "EJ Sorscher"

"G Wang"

"G Berkers" "JF Dekkers" "CK van der Ent" "JM Beekman" "HR de Jonge" "I Bronsveld" "HM Janssens" "P Van Mourik" "AM Vonk" "KM de Winter-de Groot" "E Kruisselbrink"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"TC Hwang" "Y Sohma" "YC Yu"

"G Li" "KL Kirk" "K Bernard" "W Wang"

"I Dey" "K Shah" "NA Bradbury"

"DW Vermeer" "AL Berger" "MJ Welsh" "LS Ostedgaard" "PH Karp" "CO Randak"

"H Miki" "A Hanyuda" "TC Hwang" "Y Nakamura" "Y Abe" "SG Bompadre" "Y Sohma" "K Tanaka" "M Yasui" "Y Matsuzaki" "YC Yu"

CID is 969516
synonyms found at PubChem are:
curcumin, 458-37-7, Diferuloylmethane, Natural yellow 3, Turmeric yellow, Curcuma, Turmeric, Kacha haldi, Gelbwurz, Indian saffron, Curcumin I, Souchet, Haidr, Halad, Haldar, Halud, Merita earth, Terra Merita, Yellow Ginger, Yellow Root, Safran d'Inde, Yo-Kin, Golden seal, Orange Root, C.I. Natural Yellow 3, Curcumine, Hydrastis, Indian turmeric, Yellow puccoon, Curcuma oil, Diferaloylmethane, Turmeric extract, Oils, curcuma, Kurkumin [Czech], (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione, Tumeric yellow, Turmeric oil, Oil of turmeric, CI Natural Yellow 3, Turmeric oleoresin, Curcuma longa oils, Zlut prirodni 3 [Czech], Cucurmin, Kurkumin, C.I. 75300, Tumeric oleoresin, Zlut prirodni 3, Turmeric root oil, Turmeric, oleoresin, Curcuma oil (Curcuma longa), curouma, E 100, Curcurmin, Diferulylmethane, kachs haldi, safra d'inde, Turmeric oil (Curcuma longa L.), Curcuma longa l. root oil, 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, NSC32982, UNII-IT942ZTH98, NSC 32982, Tu rmeric root oil, Turmeric (>98% curcurmin), 98% curcurmin), FEMA No. 3085, FEMA No. 3086, CCRIS 3257, CCRIS 5804, CHEBI:3962, 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione, MLS000069631, Turmeric oleoresin (79%-85% curcumin), Curcuma longa l. oil, HSDB 4334, Turmeric root oleoresin, 1,5-Di(vanillyliden)acetylaceton, NCI-C61325, C21H20O6, 1,5-Divanillyliden-2,4-pentandion, EINECS 207-280-5, Turmeric extract (Curcuma longa L.), 8024-37-1, 1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione, CHEMBL140, Curcuma longa l. oleoresin, NSC 687842, BRN 2306965, 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-, CI 75300, SMR000058237, 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-, IT942ZTH98, Curcuma longa l. root oleoresin, VFLDPWHFBUODDF-FCXRPNKRSA-N, (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, NSC-32982, NSC687842, NCGC00017159-05, DSSTox_CID_1421, (1E,6E)-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,6-diene-3,5-dione, (1E,6E)-1,7-bis[4-hydroxy-3-(methyloxy)phenyl]hepta-1,6-diene-3,5-dione, DSSTox_RID_78861, DSSTox_GSID_31077, CU-01000001305-2, CURCUMIN (SEE ALSO TUMERIC, OLEORESIN (10105-J)), 2,7-Nonadiene-4,6-dione, 1,9-bis(4-hydroxy-3-methoxyphenyl)-, Oils, galangal, PREVENTION 4 (CURCUMIN) (SEE ALSO TUMERIC, OLEORESIN (10105-J)), TURMERIC, OLEORESIN (CURCUMIN) (SEE ALSO CURCURMIN (458-37-7)), Yellow, Turmeric, 91884-86-5, CAS-458-37-7, 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, SR-01000000149, diferuloylmethan, E 100 (Dye), Haldar, Souchet, Natural Yellow3, Curcumin,(S), Curcumin (Natural), trans,trans-Curcumin, Opera_ID_1627, D07SDQ, D0H8LC, AC1LJ6T6, SCHEMBL8440, SCHEMBL8441, Curcumin, analytical standard, 4-08-00-03697 (Beilstein Handbook Reference), MLS001148449, BIDD:ER0479, turmeric root oil CO2 extract, AC1Q46A0, cid_969516, GTPL7000, turmeric root oil hydrodistilled, DTXSID8031077, SCHEMBL13521974, BDBM29532, cid_5281767, BIC8500, cMAP_000052, MolPort-001-763-682, HMS2233K04, HMS3649K06, ZINC899824, BB_NC-01422, BCP04695, HY-N0005, ZX-AT003872, Tox21_110803, Tox21_111505, Tox21_201116, BBL027711, BDBM50067040, BDBM50140172, BG0601, CC0179, CCG-36020, CCG-36107, GP8291, LS-125, MFCD00008365, SBB006495, STL371943, AKOS001305497, BCP9000557, CS-1490, curcuma longa l. root oil CO2 extract, DB11672, LS-2189, NSC-687842, OR24598, RTR-032605, curcuma longa l. root oil hydrodistilled, NCGC00017159-04, NCGC00017159-06, NCGC00017159-07, NCGC00017159-09, NCGC00017159-10, NCGC00017159-11, NCGC00017159-12, NCGC00023332-03, NCGC00023332-04, NCGC00023332-05, NCGC00258668-01, AC-24238, AN-23454, BC678109, M212, SC-17381, ST055629, BCP0726000035, DB-002681, KB-251224, TR-032605, WLN: 1OR BQ E1U1V1V1U1R DQ CO1, N1839, 1,3-Di(3-methoxy-4-hydroxystyryl)propanedial, 1790-EP2305629A1, 1790-EP2308861A1, J10108, K00009, W-5038, Curcumin, from Curcuma longa (Turmeric), powder, 458C377, Curcumin, primary pharmaceutical reference standard, 1,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, I06-0010, I06-2497, SR-01000000149-2, SR-01000000149-5, BRD-K07572174-001-02-2, BRD-K07572174-001-19-6, BRD-K07572174-001-22-0, I14-19358, Curcumin, >=94% (curcuminoid content), >=80% (Curcumin), 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)1,6-heptadiene-3,5-dione, 1,7-DI(4-HYDROXY-3-METHOXYPHENYL)HEPTA-1,6-DIENE-3, Curcumin, matrix substance for MALDI-MS, >=99.5% (HPLC), Curcumin, United States Pharmacopeia (USP) Reference Standard, 1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione, 1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), (1E,6E)-1,7-bis(3-methoxy-4-oxidanyl-phenyl)hepta-1,6-diene-3,5-dione, (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione #, (1E,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione, (1Z,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione, 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (E,E)-, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one, 5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one, Curcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one, 15845-47-3, 33171-04-9, 73729-23-4, 79257-48-0, Curcumin solution, ~0.1 % (w/v) (in ethanol with 2M HCl (99:1 v/v)), for TLC derivatization

ID: 3

InChIKey: FJNFVCAHHFNREI-UHFFFAOYSA-N
SMILES: CC(C1=NC2=CC=CC=C2C(=N1)OC3CCCCC3)N4CCN(CC4)S(=O)(=O)C5=CC=C(C=C5)OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

"N Liu" "D Rotin" "HR de Jonge" "BJ Scholte" "JW Hanrahan" "M Wilke" "R Robert" "GW Carlile" "J Liao" "P Lesimple" "H Balghi" "B Kus" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "K Varga" "J Fortenberry" "LC Pyle" "J Collawn" "M Mazur" "EJ Sorscher" "A Jurkevante" "SM Rowe" "B Woodworth" "L Fan" "PA Sloane" "J Fulton" "Y Li"

"AI Esposito" "U Pfeffer" "E Sondo" "E Caci" "LJ Galietta" "V Tomati" "N Pedemonte"

"RJ Andersen" "L Yan" "HM Sampson" "CA Gray" "JW Hanrahan" "RM Centko" "R Robert" "GW Carlile" "J Liao" "DE Williams" "RA Keyzers" "KA Teske" "RG Linington" "D Zhang" "SM Anjos" "DY Thomas"

"CE Bear" "LJ Huan" "L Wellhauser" "P Kim Chiaw" "M Ramjeesingh"

"F Ciciriello" "HM Sampson" "J Goepp" "JW Hanrahan" "R Robert" "R Phillipe" "D Waller" "DL Zhang" "GW Carlile" "F Dantzer" "J Liao" "P Lesimple" "P Ferraro" "SM Anjos" "H Balghi" "DY Thomas"

"Y Wang" "MC Bartlett" "DM Clarke" "TW Loo"

CID is 11957831
synonyms found at PubChem are:
815592-21-3, 4-(cyclohexyloxy)-2-(1-(4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl)ethyl)quinazoline, CFcor-325, VRT-325, 4-(Cyclohexyloxy)-2-(1-(4-(4-methoxyphenylsulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxybenzene)sulfonyl]piperazin-1-yl}ethyl)quinazoline, ACMC-20p1e2, GTPL4340, SCHEMBL3822809, VRT325, CHEMBL1257047, CTK9A5799, DTXSID00474707, VRT 325, MolPort-006-415-015, KS-000000GF, AKOS030228615, 4-cyclohexyloxy-2-[1-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethyl]quinazoline, KB-01359, KB-34900, A1-01884, 4-(Cyclohexyloxy)-2-(1-(4-((4-methoxyphenyl)sulfonyl)piperazin-1-yl)ethyl)quinazoline, 4-(cyclohexyloxy)-2-(1-{4-[(4-methoxyphenyl)sulfonyl]-1-piperazinyl}ethyl)quinazoline

ID: 4

InChIKey: UQRORFVVSGFNRO-UTINFBMNSA-N
SMILES: CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O

biological descriptors:

reference list:

"F Becq" "P Melin" "C Norez" "H Jorna" "H DeJonge" "M Bijvelds" "S Noel" "M Wilke"

"F Becq" "S Thibaudeau" "I Adachi" "T Legigan" "C Norez" "J Désiré" "A Kato" "M Forcella" "Y Blériot" "J Bertrand" "P Parenti" "V Cendret" "A Mingot"

"F Becq" "M Jollivet Souchet" "R Ferru-Clément" "C Boinot"

"A Leonard" "T Leal" "J Dingemanse" "P Lebecque"

"F Becq" "C Norez" "F Antigny" "C Vandebrouck" "S Noel"

"A Leonard" "B Lubamba" "T Leal" "J Lebacq" "P Lebecque" "R Vanbever" "P Wallemacq"

"F Becq" "S Noël" "HR De Jonge" "M Wilke" "AG Bot"

CID is 51634
synonyms found at PubChem are:
Miglustat, Zavesca, N-Butyldeoxynojirimycin, 72599-27-0, NB-DNJ, N-Butylmoranoline, N-butyl-1-deoxynojirimycin, BuDNJ, n-Butyl deoxynojirimycin, Butyldeoxynojirimycin, (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol, n-Butyl dnj, N-(n-Butyl)deoxynojirimycin, SC-48334, Miglustat [USAN], OGT 918, N-Butyl-DNJ, SC 48334, miglustatum, Vevesca, UNII-ADN3S497AZ, Zavesca (TN), OGT-918, 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, (2R,3r,4R,5S)-, N-Bu-DNJ, Miglustat, Hydrochloride, N-Butyl-deoxynojirimycin, SC48334, ADN3S497AZ, CHEMBL1029, CHEBI:50381, D-Glucitol, 1,5-(butylimino)-1,5-dideoxy-, 1,5-Dideoxy-1,5-N-butylimino-D-glucitol, DSSTox_CID_25618, DSSTox_RID_81006, DSSTox_GSID_45618, N-(n-butyl)-1,5-dideoxy-1,5-imino-D-glucitol, 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))-, NBV, CAS-72599-27-0, Brazaves, Miglustat [USAN:INN:BAN], NCGC00018140-02, Brazaves (TN), Miglustat (USAN/INN), AC1L1BHJ, D0HR8Z, Miglustat (JAN/USAN/INN), SCHEMBL246893, BICL4040, GTPL4841, DTXSID6045618, BDBM18355, UQRORFVVSGFNRO-UTINFBMNSA-N, HMS2090N20, ZINC3794711, Tox21_110830, 3917AH, AN-010, MFCD00272581, AKOS028109118, Tox21_110830_1, ACN-025888, API0003392, CS-2776, DB00419, NCGC00024452-03, NCGC00024452-04, BC677641, HY-17020, LS-116261, N-(n-Butyl)-1-deoxynojirimycin min. 99%, N-Butyldeoxynojirimycin, film (dried in situ), D05032, AB00489939-10, SR-01000000043, SR-01000000043-2, W-203639, 134282-77-2

ID: 5

InChIKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N
SMILES: C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment Apical membrane & subapical compartment

reference list:

"S Moriceau" "M Kelly" "G Planelles" "J Colas" "J Fritsch" "N Hamdaoui" "M Baudoin-Legros" "A Aissat" "A Edelman" "DL Vieu"

"Y Jai" "K Shah" "NA Bradbury" "RJ Bridges"

"BA Woodworth" "DF Skinner" "CM McNicholas" "AC Blount" "JC Kappes" "M Chestnut" "S Zhang" "EJ Sorscher"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"T Leal" "C Bouckaert" "A Capron" "B Dhooghe" "P Wallemacq" "S Noel"

"I Dey" "K Shah" "NA Bradbury"

CID is 445154
synonyms found at PubChem are:
resveratrol, 501-36-0, trans-resveratrol, 3,4',5-Trihydroxystilbene, (E)-5-(4-Hydroxystyryl)benzene-1,3-diol, 3,5,4'-Trihydroxystilbene, (E)-resveratrol, 3,4',5-Stilbenetriol, Resvida, 3,4',5-Trihydroxy-trans-stilbene, 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, SRT-501, SRT501, Resveratol, SRT 501, 3,5,4'-Trihydroxy-trans-stilbene, 5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol, 3,4',5-trihydroxy-stilbene, Resveratrol, natural, UNII-Q369O8926L, CHEBI:45713, trans-3,4',5-trihydroxystilbene, (E)-5-(p-Hydroxystyryl)resorcinol, trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene, 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, CHEMBL165, NSC 327430, (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol, MLS000069735, 1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)-, LUKBXSAWLPMMSZ-OWOJBTEDSA-N, KUC104385N, PREVENTION 8 (RESVERATROL), C14H12O3, trans-3,4',5 - trihydroxystilbene, NSC327430, KSC-10-164, Q369O8926L, 5-((1E)-2-(4-Hydroxyphenyl)ethenyl)-1,3-benzenediol, RM-1812, trans-3,4′,5-Trihydroxystilbene, SMR000058206, R 5010, DSSTox_CID_11980, DSSTox_RID_78898, DSSTox_GSID_31980, CU-01000001503-3, (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol, (E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol, 1,3-Benzenediol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-, MFCD00133799, STL, SR-01000000163, 5-[(1E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol, CHEBI:27881, CCRIS 8952, HSDB 7571, 3fts, 4jaz, 4qer, Resveratrol, E-, Resveratrol,(S), Stilbene, 2f, TaxusChinensisiRehd, NCGC00015894-02, CAS-501-36-0, Prestwick_619, Trans-3,4&prime, Resveratrol, trans-, Resveratrol, synthetic, Opera_ID_586, AC1L9HIC, Prestwick2_000508, Prestwick3_000508, Spectrum5_000552, D0U3EP, Lopac0_001111, REGID_for_CID_6240, SCHEMBL19425, BSPBio_000435, BSPBio_001114, BSPBio_003461, MLS001055357, MLS001076538, MLS001424228, MLS002207121, MLS002222231, ARONIS24568, SPECTRUM1502223, BPBio1_000479, cid_445154, GTPL8741, SGCUT00007, trans-Stilbene-3,4',5-triol, ZINC6787, Resveratrol, analytical standard, DTXSID4031980, REGID_for_CID_445154, BDBM23926, Resveratrol, >=99% (HPLC), BBC/741, BIK9013, 2l98, MolPort-002-499-801, BCPP000091, HMS1362H15, HMS1569F17, HMS1792H15, HMS1921N04, HMS1990H15, HMS2052I09, HMS2096F17, HMS2232A18, HMS3263O04, HMS3403H15, HMS3649A20, ACT09778, BCP01416, to_000079, ZX-AS004941, ZX-AT013797, Tox21_110257, Tox21_201374, Tox21_303376, Tox21_501111, ABP000376, AC-727, AN-865, BBL028252, BS0159, CCG-38874, CR-003, GP2549, GP5884, LMPK13090005, s1396, SBB055452, STL146386, AKOS005720936, Tox21_110257_1, ACN-034773, API0000480, CS-1050, DB02709, KS-5047, LP01111, LS-2146, MCULE-5678456463, NC00349, NSC-327430, OR46018, RP17549, SDCCGMLS-0002998.P003, IDI1_002152, Resveratrol solution, 100 mM in DMSO, NCGC00017352-05, NCGC00017352-06, NCGC00017352-07, NCGC00017352-08, NCGC00017352-09, NCGC00017352-10, NCGC00017352-11, NCGC00017352-12, NCGC00017352-13, NCGC00017352-14, NCGC00017352-15, NCGC00017352-16, NCGC00017352-17, NCGC00017352-18, NCGC00017352-19, NCGC00017352-24, NCGC00024003-00, NCGC00024003-04, NCGC00024003-05, NCGC00024003-06, NCGC00024003-07, NCGC00024003-08, NCGC00024003-09, NCGC00024003-10, NCGC00024003-11, NCGC00024003-12, NCGC00024003-13, NCGC00024003-14, NCGC00257465-01, NCGC00258925-01, NCGC00261796-01, 375823-41-9, 4CN-0696, AJ-08292, AK-39118, AS-12413, BC202036, BR-39118, CC-34242, CJ-00111, CPD000058206, HY-16561, KB-02515, SAM001246888, SC-11924, ST057251, SY014849, ZB000650, AB0006623, AX8004672, ST2408097, TL8003323, EU-0101111, FT-0082623, N1848, R0071, Resveratrol, Vetec(TM) reagent grade, 98%, 01R360, C03582, J10118, N88795, 5-[2-(4-hydroxyphenyl)vinyl]-1,3-benzenediol, AB00052942-29, AB00052942_31, A827984, 5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzoldiol, I06-0437, SR-01000000163-3, SR-01000000163-4, SR-01000000163-9, 5-[(E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, 5-[(E)-2-(4-Hydroxyphenyl)ethenyl]benzol-1,3-diol, 5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol, 5[(E)-2-(4-Hydroxyphenyl)-vinyl]benzene 1,3-diol, BRD-K25591257-001-01-2, BRD-K80738081-001-06-2, BRD-K80738081-001-07-0, BRD-K80738081-001-09-6, BRD-K80738081-001-10-4, BRD-K80738081-001-23-7, SR-01000000163-10, SR-01000000163-11, SR-01000000163-16, (E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, (E)1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol, Resveratrol, certified reference material, TraceCERT(R), 1,3-Benzenediol, 5-[(E)-2-(4-hydroxyphenyl)ethenyl]-, Resveratrol, European Pharmacopoeia (EP) Reference Standard, 533C1DA0-4104-42B5-9D32-9265F40857E4, trans-Resveratrol, United States Pharmacopeia (USP) Reference Standard, 3,4',5-Trihydroxy-trans-stilbene 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol, InChI=1/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1, trans-3,5,4'-Trihydroxystilbene3,4',5-Stilbenetrioltrans-Resveratrol(E)-5-(p-Hydroxystyryl)resorcinol(E)-5-(4-hydroxystyryl)benzene-1,3-diol

ID: 6

InChIKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N
SMILES: CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"SM Rowe" "BA Woodworth" "SB Hicks" "D Skinner" "BT Conger" "S Zhang" "EJ Sorscher"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"AS Verkman" "W Namkung" "J Park" "Y Seo"

"JP Clancy" "K Varga" "J Fortenberry" "LC Pyle" "J Collawn" "M Mazur" "EJ Sorscher" "A Jurkevante" "SM Rowe" "B Woodworth" "L Fan" "PA Sloane" "J Fulton" "Y Li"

"Z Servetnyk" "C Andersson" "GM Roomans"

CID is 47936
synonyms found at PubChem are:
forskolin, Colforsin, 66575-29-9, Coleonol, colforsina, colforsine, colforsinum, Boforsin, Colforsine [French], Colforsinum [Latin], Colforsina [Spanish], Coleonolk, Colforsin [USAN:INN], UNII-1F7A44V6OU, 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one, EINECS 266-410-9, HL 362, NSC 357088, NSC 375489, Forskolin, Coleus forskohlii, CHEMBL52606, 1F7A44V6OU, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate, L 75 1362B, CHEBI:42471, HL-362, NSC375489, 64657-11-0, NCGC00024996-02, L-751362B, 7-beta-Acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one, DSSTox_CID_20484, DSSTox_RID_79500, DSSTox_GSID_40484, Forsklin, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-Dodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-3-vinyl-1H-naphtho(2,1-b)pyran-1-one 5-acetate, 66428-89-5, C22H34O7, ForsLean, 7beta-Acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxy-labd-14-en-11-one, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate, 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))-, 1H-Naphtho(2,1-b)pyran-1-one, dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-pentamethyl-6,10,10b-trihydroxy-, (3R-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))-, 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-, FOK, SMR000471881, CAS-66575-29-9, Ocufors, Timsaponin-C, Colforsin (USAN/INN), D0Y7VM, forskolin/ rolipram mixture, MolMap_000021, AC1L2J1R, AC1Q1L8K, SCHEMBL4928, 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, cid_47936, MLS001066384, MLS001333255, MLS001333256, MLS002172462, MLS002695942, Forskolin, analytical standard, Forskohlii Root Extract (ForsLean)(20% forskohlin), REGID_for_CID_47936, GTPL5190, DTXSID8040484, BCBcMAP01_000132, OHCQJHSOBUTRHG-KGGHGJDLSA-, AOB6380, BIF1031, MolPort-002-493-717, OHCQJHSOBUTRHG-KGGHGJDLSA-N, ZX-AFC000211, Bio1_000443, Bio1_000932, Bio1_001421, HMS2235C17, HMS3267I16, ZINC3977779, Tox21_110940, Tox21_302399, BDBM50010261, MFCD00082317, s2449, AKOS024456384, Tox21_110940_1, ACN-035218, AM81249, CS-1454, DB02587, LMPR0104030004, PXT0000105, SMP1_000128, NCGC00024996-03, NCGC00024996-04, NCGC00024996-05, NCGC00024996-06, NCGC00177971-03, NCGC00255526-01, 5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one, AS-17443, CC-28833, HY-15371, LS-95557, SC-47275, F0855, FT-0626543, V0151, Y0448, 7088-EP2280000A1, 7088-EP2284169A1, 7088-EP2287147A2, 7088-EP2287161A1, 7088-EP2287162A1, 7088-EP2287165A2, 7088-EP2287166A2, 7088-EP2292620A2, 7088-EP2295550A2, 7088-EP2301931A1, 7088-EP2301937A1, 7088-EP2308562A2, 7088-EP2311806A2, 7088-EP2371811A2, C09076, D03584, MLS-0318096.0001, S-7769, C-21901, SR-01000597378, Forskolin, For use in molecular biology applications, Q-200888, SR-01000597378-1, BRD-K09602097-001-04-5, Forskolin, from Coleus forskohlii, >=98% (HPLC), powder, Forskolin, United States Pharmacopeia (USP) Reference Standard, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate, [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate, [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate, [3R-(3?,4a?,5?,6?,6a?,10?,10a?,10b?)]-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one, [3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-5-(Acetyloxy)-3-e thenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one, 1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-, 72569-68-7, InChI=1/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

ID: 7

InChIKey: PURKAOJPTOLRMP-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C

biological descriptors:

CFTR relevance: CFTR stimulator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"RW Hofland" "AC de Kiviet" "HGM Arets" "MA Kruijswijk" "S Schotman" "CK van der Ent" "S Michel" "KM de Winter-de Groot" "HGM Heijerman" "MMM van Oirschot-van de Ven" "BL Aalbers"

"K Conrath" "TC Hwang" "L Qiu" "X Zou" "HI Yeh" "Y Sohma"

"CM Farinha" "AM Matos" "FR Pinto" "P Jordan" "P Matos" "CA Loureiro" "JD Santos"

"G Cui" "JS Hong" "BB Stauffer" "A Rab" "NA McCarty" "BR Imhoff" "EJ Sorscher"

"G Cui" "BB Stauffer" "N Khazanov" "DT Infield" "H Senderowitz" "NA McCarty" "BR Imhoff"

"SM Rowe" "MA Mall" "CM McKee" "SM Moskowitz" "J Savage" "F Xuan" "EF McKone" "BW Ramsey" "E Tullis" "JL Taylor-Cousar" "D Waltz" "G Marigowda"

"JS Hong" "KL Kirk" "A Rab" "W Wang" "EJ Sorscher"

"A Munck" "C Simard" "J Lekstrom-Himes" "CK van der Ent" "JS Elborn" "Y Lu" "A Moeller" "EP Ingenito" "EF McKone" "LT Wang" "JL Taylor-Cousar" "C McKee"

"K McBennett" "SB Donnola" "CA Flask" "B Kaminski" "M O'Riordan" "R Gubitosi-Klug" "TJ Sferra" "K Kutney"

"G Berkers" "JF Dekkers" "CK van der Ent" "JM Beekman" "HR de Jonge" "I Bronsveld" "HM Janssens" "P Van Mourik" "AM Vonk" "KM de Winter-de Groot" "E Kruisselbrink"

"F Becq" "L Froux" "E Sage" "C Coraux"

"L Ragionieri" "L Delang" "E Dreassi" "A Mancini" "F Ravanetti" "G Tagliavini" "C Mirabelli" "C Zamperini" "S Bertoni" "M Radi" "K Lanko" "G Maga" "P Vergani" "G Fontò" "J Neyts" "S Palese" "M Kissova" "E Langron" "E Crespan" "C Giorgio" "S Tassini"

"R Robert" "GW Carlile" "J Goepp" "Y Luo" "E Matthes" "JW Hanrahan" "K Dejgaard" "A Billet" "DY Thomas"

"AG Kaditis" "I Loukou" "A Petrocheilou"

"S Hadida" "M Miller" "JJ Wine" "M Ashlock" "F Van Goor" "JH Stack" "ER Olson" "PA Negulescu" "KS Straley" "B Burton" "CJ Decker" "J McCartney" "PD Grootenhuis" "RA Frizzell"

"TC Hwang" "WY Lin" "Y Sohma"

"K Montemayor" "AT Claudio" "NE West" "S Carson" "MS Christianson" "N Lechtzin"

"L Maiuri" "M Piacentini" "A Tosco" "V Raia" "VR Villella" "G Kroemer"

"JA Lekstrom-Himes" "JC Davies" "L Viswanathan" "SH Donaldson" "M Griese" "Group. VX11-661-101 Study" "E Tullis" "LT Wang" "J Cooke" "JM Pilewski"

"D Campbell" "JC Davies" "M Rosenfeld" "J Schneider" "S Tian" "group. ARRIVAL study" "M Higgins" "LT Wang" "CE Wainwright" "S Cunningham" "C McKee"

"A Hinzpeter" "M Fayon" "D Grenet" "M Thumerel" "N Stremler-Le Bel" "A Edelman" "JP Jais" "J Mazenq" "V Urbach" "P Bonnette" "E Girodon-Boulandet" "F Le Pimpec-Barthes" "I Sermet-Gaudelus" "A Carsin" "A Hatton" "IM Pranke" "M Mesbahi" "J Simonin"

CID is 16220172
synonyms found at PubChem are:
Ivacaftor, 873054-44-5, VX-770, Kalydeco, Ivacaftor (VX-770), N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, VX 770, VX770, UNII-1Y740ILL1Z, Kalydeco (TN), CHEBI:66901, N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, 1Y740ILL1Z, 3-Quinolinecarboxamide, N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxo-, Ivacaftor [USAN:INN], ivacaftorum, 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, Ivacaftor D18, Tube715, Ivacaftor (USAN/INN), VX-770 - Ivacaftor, D0W7WC, MLS006011119, SCHEMBL351373, GTPL4342, QUI135, VX-770, Ivacaftor, Kalydeco, CHEMBL2010601, DTXSID00236281, EX-A441, QCR-155, MolPort-009-194-229, PURKAOJPTOLRMP-UHFFFAOYSA-N, BCPP000199, HMS3654E10, AOB31714, ABP000259, BDBM50032693, s1144, VX-770/VX770, ZINC52509463, AKOS015994762, AKOS032950001, BCP9000799, CS-0497, DB08820, EX-7211, LE-0002, KS-0000063W, NCGC00242480-01, 4CA-0661, AC-28324, AN-16981, BC660099, HY-13017, KB-81476, SC-95534, SMR004702900, AB0008116, AB2000007, FT-0696681, X7565, A25626, D09916, W-5681, AB01565806_02, VX770, VX 770, Ivacaftor, 873054-44-5, N-(2,4-ditert-butyl-5-hydroxy-phenyl)-4-oxo-1H-quinoline-3-carboxamide, N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, 1134822-00-6, 1174930-71-2, 1413431-05-6, Kalydeco|||N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide

ID: 8

InChIKey: RDOBOPJBMQURAT-UHFFFAOYSA-N
SMILES: CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CSC(=N3)NC4=C(C=CC(=C4)Cl)OC

biological descriptors:

reference list:

"F Becq" "M Jollivet Souchet" "R Ferru-Clément" "C Boinot"

"K Tarnowski" "P Zielenkiewicz" "F Becq" "D Tondelier" "C Norez" "A Roldan" "J Colas" "J Fritsch" "MF da Cunha" "S Bitam" "EL Saussereau" "N Servel" "A Edelman" "M Ollero" "GL Lukacs" "P Melin-Heschel" "L Wiszniewski" "M Dadlez" "G Wieczorek" "A Kupniewska" "N Odolczyk" "H Herrmann" "G Faure"

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

"JP Clancy" "K Varga" "J Fortenberry" "LC Pyle" "J Collawn" "M Mazur" "EJ Sorscher" "A Jurkevante" "SM Rowe" "B Woodworth" "L Fan" "PA Sloane" "J Fulton" "Y Li"

"AI Esposito" "U Pfeffer" "E Sondo" "E Caci" "LJ Galietta" "V Tomati" "N Pedemonte"

"Y Wang" "MC Bartlett" "DM Clarke" "TW Loo"

CID is 1144671
synonyms found at PubChem are:
Corr-4a, RDOBOPJBMQURAT-UHFFFAOYSA-N, 421580-53-2, ST075396, N-(2-(5-Chloro-2-methoxyphenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)benzamide, MLS000561131, Oprea1_189688, Oprea1_471654, SCHEMBL837666, CHEMBL260775, DTXSID00360737, MolPort-001-986-142, ZINC888741, AKOS001665304, MCULE-2724995336, BAS 02936954, KB-57187, SMR000156156, EU-0078205, MLS-0094194.0001, SR-01000492559, SR-01000492559-1, N-[2-(5-Chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2' -yl]-benzamide, N-[2-(5-Chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzami, N-[2-(5-Chloro-2-methoxyphenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]benzamide, N-{2-[(5-chloro-2-methoxyphenyl)amino]-4'-methyl-4,5'-bi-1,3-thiazol-2'-yl}benzamide, N-(5-{2-[(5-chloro-2-methoxyphenyl)amino](1,3-thiazol-4-yl)}-4-methyl(1,3-thia zol-2-yl))benzamide

ID: 9

InChIKey: KZNIFHPLKGYRTM-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function inconsistent assignment
Order of interaction unknown
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

"AD Floyd" "PL Zeitlin" "E Kwon" "M Lim" "K McKenzie"

CID is 5280443
synonyms found at PubChem are:
apigenin, 520-36-5, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Chamomile, Spigenin, Versulin, Apigenol, 4',5,7-Trihydroxyflavone, Apigenine, C.I. Natural Yellow 1, 5,7,4'-Trihydroxyflavone, Pelargidenon 1449, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, 2-(p-Hydroxyphenyl)-5,7-dihydroxychromone, UCCF 031, NSC 83244, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, UNII-7V515PI7F6, 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one, CCRIS 3789, CHEBI:18388, CHEMBL28, EINECS 208-292-3, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-, BRN 0262620, FLAVONE, 4',5,7-TRIHYDROXY-, 4′,5,7-Trihydroxyflavone, KZNIFHPLKGYRTM-UHFFFAOYSA-N, 7V515PI7F6, NSC83244, NSC-83244, CAS-520-36-5, ST056301, DSSTox_CID_2391, DSSTox_RID_76568, DSSTox_GSID_22391, Q-100586, Q-200822, SMR000326850, SR-01000075663, Chamomile Powder, HSDB 7573, 4der, 4dgm, 4hkk, Naringenin, 18, Prestwick_719, Apigenin, 13, PubChem9831, Tocris-1227, 3cf9, 4',7-Trihydroxyflavone, BiomolKI_000078, Prestwick0_000414, Prestwick1_000414, Prestwick2_000414, Prestwick3_000414, Spectrum2_000428, Spectrum3_001882, Spectrum4_001999, Lopac-A-3145, BiomolKI2_000082, D00RIX, 4,5, 7-Trihydroxyflavone, AC1NQX15, Lopac0_000065, Oprea1_622293, SCHEMBL19428, 4',5,7-trihydroxy-Flavone, Apigenin, analytical standard, BSPBio_000368, BSPBio_003384, KBioGR_002565, SPECTRUM200846, 5-18-04-00574 (Beilstein Handbook Reference), MLS000697626, MLS000859991, MLS001074874, MLS006011839, BIDD:ER0135, DivK1c_000798, SCHEMBL222227, SPBio_000416, SPBio_002307, ghl.PD_Mitscher_leg0.1194, BDBM7458, BPBio1_000406, GTPL4136, MEGxp0_000176, DTXSID6022391, ACon1_002450, cid_5280443, HMS502H20, KBio1_000798, KBio3_002887, BIK9018, OR7265T, MolPort-001-740-354, NINDS_000798, ZX-AFC000435, Bio1_000376, Bio1_000865, Bio1_001354, HMS1569C10, HMS1922P22, HMS2096C10, HMS2230D17, HMS3260M11, HMS3267D21, HMS3373B18, HMS3561P09, HMS3655D18, Apigenin, >=95.0% (HPLC), 4',5,7-Trihydroxyflavone, 97%, ACN-S003241, BCP28288, HY-N1201, ZINC3871576, ZX-AT019281, Tox21_201542, Tox21_302884, Tox21_500065, Apigenin; 4',5,7-Trihydroxyflavone, BBL010499, BS0030, CCG-40061, GP1532, HSCI1_000221, LMPK12110005, MFCD00006831, s2262, SBB066087, STK801630, AKOS002140699, AC-8011, ACN-034762, AN-8432, CS-5432, DB07352, EBD2138579, LP00065, LS-2209, MCULE-6141069907, ND-9076, SDCCGMLS-0066379.P001, TRA0067512, IDI1_000798, SMP2_000338, Apigenin, >=97% (TLC), from citrus, NCGC00015049-01, NCGC00015049-02, NCGC00015049-03, NCGC00015049-04, NCGC00015049-05, NCGC00015049-06, NCGC00015049-07, NCGC00015049-08, NCGC00015049-09, NCGC00015049-10, NCGC00015049-11, NCGC00015049-12, NCGC00015049-13, NCGC00015049-14, NCGC00015049-15, NCGC00015049-16, NCGC00015049-18, NCGC00025057-01, NCGC00025057-02, NCGC00025057-03, NCGC00025057-04, NCGC00025057-05, NCGC00025057-06, NCGC00025057-07, NCGC00025057-08, NCGC00025057-09, NCGC00169835-01, NCGC00169835-02, NCGC00169835-03, NCGC00256419-01, NCGC00259092-01, NCGC00260750-01, 4CN-0925, AJ-46351, AK-88794, CC-24158, CJ-10995, KB-78227, NCI60_041830, SC-05011, SY005957, TS-00897, AB0010536, AB1011450, AX8015784, LY 080400, ST2411642, TC-307820, TR-018510, EU-0100065, FT-0622445, FT-0623582, N1828, 20A365, A 3145, C01477, J10341, K00045, M-6923, Apigenin, >=97% (TLC), from parsley, powder, Biochem Biophys Res Comm 212: 767 (1997), 4 inverted exclamation marka,5,7-Trihydroxyflavone, 5,7-dihydroxy-2-(4-hydroxyphenyl)-chromen-4-one, Apigenin, primary pharmaceutical reference standard, C-16977, 4 inverted exclamation mark ,5,7-trihydroxyflavone, I06-0221, SR-01000075663-1, SR-01000075663-3, SR-01000075663-7, SR-01000075663-8, BRD-K01493881-001-10-4, BRD-K01493881-001-17-9, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one #, 4H-1-Benzopyran-4-one,7-dihydroxy-2-(4-hydroxyphenyl)-, D50A2D8A-6D8B-4708-B21E-2DE9580D033F, Apigenin, United States Pharmacopeia (USP) Reference Standard, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)- (9CI), 461015-54-3, 8002-66-2

ID: 10

InChIKey: OBKXEAXTFZPCHS-UHFFFAOYSA-M
SMILES: C1=CC=C(C=C1)CCCC(=O)[O-]

biological descriptors:

CFTR relevance: little or no effect

Category:
Influence on CFTR function likely enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"L Qian" "AS Verkman" "Y Song" "D Salinas" "LJ Galietta" "N Pedemonte" "ND Sonawane"

"AD Floyd" "PL Zeitlin" "E Kwon" "M Lim" "K McKenzie"

"Z Servetnyk" "C Andersson" "GM Roomans"

CID is 22053264
synonyms found at PubChem are:
4-phenylbutanoate, 4-Phenylbutyric acid anion, BDBM36184, CHEBI:75317, OBKXEAXTFZPCHS-UHFFFAOYSA-M, AKOS024437455, CJ-00370, ZB001717, J3.540.463E, AB01275463-01, AB01275463_02, A812651

ID: 11

InChIKey: WBSMIPAMAXNXFS-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CCCNC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function inconsistent assignment
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"TC Hwang" "WY Lin" "Y Sohma"

"G Cui" "JS Hong" "BB Stauffer" "A Rab" "NA McCarty" "BR Imhoff" "EJ Sorscher"

"G Wang"

"G Li" "KL Kirk" "K Bernard" "W Wang"

"G Cui" "BB Stauffer" "N Khazanov" "DT Infield" "H Senderowitz" "NA McCarty" "BR Imhoff"

CID is 4549
synonyms found at PubChem are:
NPPB, 5-Nitro-2-(3-phenylpropylamino)benzoic acid, 107254-86-4, UNII-3A35O9G3YZ, 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid, 3A35O9G3YZ, CHEBI:34457, HOE 144, HOE-144, Benzoic acid,5-nitro-2-[(3-phenylpropyl)amino]-, Benzoic acid, 5-nitro-2-((3-phenylpropyl)amino)-, IN1196, 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID, 5-NITRO-2-PHENYLPROPYLAMINOBENZOIC ACID [NPPB], 5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB), SR-01000075336, Spectrum_001814, Tocris-0593, ACMC-20c9kv, AC1L1IEV, Spectrum2_001477, Spectrum3_001518, Spectrum4_000338, Spectrum5_001244, Lopac-N-4779, (NPPB), D08DQL, D0HW9P, UPCMLD-DP143, CBiol_001838, Lopac0_000857, BSPBio_001423, BSPBio_003195, KBioGR_000715, KBioSS_002311, MLS000859983, DivK1c_000619, SCHEMBL159244, SPBio_001433, AC1Q20U0, GTPL4270, CHEMBL1256759, UPCMLD-DP143:001, UPCMLD-DP143:002, CTK4A5098, HMS501O21, KBio1_000619, KBio2_002309, KBio2_004877, KBio2_007445, KBio3_002695, DTXSID90147978, MolPort-003-959-000, NINDS_000619, WBSMIPAMAXNXFS-UHFFFAOYSA-N, Bio1_000124, Bio1_000613, Bio1_001102, HMS1791H05, HMS1989H05, HMS2235P03, HMS3262L15, HMS3266O16, HMS3373B17, HMS3402H05, ZINC3873822, Tox21_500857, BN0393, CCG-39187, MFCD00153851, AKOS024458574, CS-8179, LP00857, IDI1_000619, NCGC00015740-01, NCGC00015740-02, NCGC00015740-03, NCGC00015740-04, NCGC00015740-05, NCGC00015740-06, NCGC00015740-07, NCGC00015740-08, NCGC00015740-09, NCGC00015740-10, NCGC00024671-01, NCGC00024671-02, NCGC00024671-03, NCGC00024671-04, NCGC00024671-05, NCGC00024671-06, NCGC00024671-07, NCGC00024671-08, NCGC00261542-01, SMR000326842, Brit J Pharmacol 117: 175 (1996), HY-101012, LS-186884, LS-187538, RT-010388, 2-PHENPROPYLAMINO-5-NITROBENZOIC ACID, 5 nitro 2 (3 phenylpropylamino)benzoic acid, B6367, EU-0100857, X6841, 5-nitro-2-(3-phenylpropylamino) benzoic acid, 5-Nitro-2-(3'-phenylpropyl-amino)benzoic acid, 5-Nitro-2-(3-phenyl-propylamino)-benzoic acid, C13705, N 4779, J-001745, SR-01000075336-1, SR-01000075336-3, 5-Nitro-2-(3-phenylpropylamino)benzoic acid, >=98%, BRD-K89272762-001-02-8, BRD-K89272762-001-04-4, BRD-K89272762-001-07-7

ID: 12

InChIKey: WMBWREPUVVBILR-WIYYLYMNSA-N
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"L Maiuri" "F De Gregorio" "S Guido" "CA Leone" "L Salvadori" "MC Maiuri" "A Zolin" "M Pettoello-Mantovani" "A Tosco" "V Raia" "G Bona" "S Esposito" "G Kroemer" "G De Rosa" "A Sepe" "D De Stefano" "A Mehta" "A Venerando" "A Bossi" "LA Pinna" "VR Villella" "R Grassia"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"H Yang" "Y Zhang" "T Ma" "L Zhu" "X Gao" "B Yu" "L Chen"

"L Maiuri" "A Di Pasqua" "F De Gregorio" "S Guido" "CA Leone" "P Buonpensiero" "G Stoll" "L Salvadori" "MC Maiuri" "A Tosco" "V Raia" "E Ferrari" "G Bona" "S Esposito" "G Kroemer" "G De Rosa" "A Sepe" "D De Stefano" "A Mehta" "S Lusa" "I Sana" "R Grassia"

CID is 65064
synonyms found at PubChem are:
(-)-Epigallocatechin gallate, EGCG, Epigallocatechin gallate, 989-51-5, Epigallocatechin 3-gallate, Epigallocatechin-3-gallate, Tea catechin, (-)-Epigallocatechin-3-o-gallate, Teavigo, (-)-Epigallocatechol gallate, Epigallocatechin-3-monogallate, (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate, Catechin deriv., UNII-BQM438CTEL, Green tea extract, CCRIS 3729, (-)-epigallocatechin 3-gallate, C22H18O11, BQM438CTEL, CHEBI:4806, CHEMBL297453, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, WMBWREPUVVBILR-WIYYLYMNSA-N, Epigallocatechol, 3-gallate, (-)-, (-)-Epigallocatechin gallate (EGCG), [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, DSSTox_CID_567, DSSTox_RID_78830, DSSTox_GSID_29889, Sunphenon, [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate, EGCG cpd, (-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate), (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate), CAS-989-51-5, SMR000449288, epigallo-catechin gallate, SR-01000759328, L-Epigallocatechin gallate, PF-EGCg 90, Epigallocate, NVP-XAA 723, (-)-EGCG, Epigallocic acid, Teavigo;, EGCG analogs, GTPs,Anagen, 2kdh, 3oob, 4awm, EGCG, Anagen, KDH, Epigallocatcchin Gallate, Spectrum_000316, SpecPlus_000277, Spectrum2_000168, Spectrum3_000244, Spectrum4_001541, Spectrum5_000102, Galloyl-L-epigallocatechol, D0E9DB, D0U2BH, AC1L22IG, AC1Q5X0Z, (-)-Epigallocatechin gallat, (-)-Epigallocatehin gallate, SCHEMBL35258, BSPBio_001628, KBioGR_002002, KBioSS_000796, SPECTRUM210239, cid_65064, EPIGALOCATECHIN GALLATE, MLS000758300, MLS001424000, DivK1c_006373, Green tea polyphenols, Anagen, SPBio_000035, Epigallocatechin gallate(EGCG), Epigallocatechin monogallate, B, GTPL7002, MEGxp0_001166, Epigallocatechin gallate, Anagen, DTXSID1029889, ACon1_001054, KBio1_001317, KBio2_000796, KBio2_003364, KBio2_005932, KBio3_001128, AOB2839, (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate, EGCG solution, 20 mM in DMSO, MolPort-001-741-358, (-)-EpigallocatechinGallateHydrate, HMS2051K21, HMS3649E08, ZINC3870412, Tox21_201468, Tox21_303457, BDBM50070942, CCG-38378, FR-109, LMPK12030005, MFCD00075940, s2250, AKOS015918182, ACN-035233, CS-1258, DB12116, DS-9030, EBD2138593, LS-2197, MCULE-3341525983, MCULE-7760530136, NC00078, SDCCGMLS-0066550.P001, (-)-Epigallocatechin gallate, >=95%, Epigallocatechin gallate analogs, Anagen, KS-0000132O, NCGC00164319-01, NCGC00164319-02, NCGC00164319-03, NCGC00164319-04, NCGC00164319-06, NCGC00257243-01, NCGC00259019-01, AN-15867, BP-30205, CPD000449288, HY-13653, K791, SAM001247031, SC-47284, ST097428, AB0014381, KB-206444, E0694, FT-0082796, FT-0604392, N1874, C09731, W-5069, (-)-Epigallocatechin gallate, >=97.0% (HPLC), (-)-Epigallocatechin gallate, analytical standard, 989E515, Epigallocatechin Gallate solution, 20 mM in DMSO, Gallic acid, 3-ester with epigallocatechol, (-)-, SR-01000946601, epigallocatechin-3-gallate solution, 20 mM in DMSO, I14-7747, Q-100914, SR-01000759328-5, SR-01000759328-6, SR-01000946601-1, (-)-EPIGALLOCATECHIN GALLATE (GREEN TEA EXTRACT), (-)-Epigallocatechin Gallate solution, 20 mM in DMSO, (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate, ANTIOXIDANT MODEL (TRAMP) -EPIGALLOCATECHIN GALLATE, UNII-T432289GYZ component WMBWREPUVVBILR-WIYYLYMNSA-N, (-)-Epigallocatechin gallate, >=80% (HPLC), from green tea, (-)-Epigallocatechin Gallate, disposable screening library format, Epigallocatechin gallate, primary pharmaceutical reference standard, (-)-Epigallocatechin-3-O-gallate, United States Pharmacopeia (USP) Reference Standard, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxyb enzoate, [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 2,3,4-trihydroxybenzoate, Epigallocatechin gallate, Pharmaceutical Secondary Standard; Certified Reference Material, (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate, (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl-3,4,5-trihydroxybenzoate, 3,4,5-Trihydroxybenzoic acid (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, 3,4-Dihydro-5,7-dihydroxy-2R-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3R-yl-3,4,5-trihydroxybenzoate, 863-65-0, Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-, Benzoic acid, 3,4,5-trihydroxy-,(2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester

ID: 13

InChIKey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
SMILES: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"N Liu" "C Pavel" "R Robert" "GW Carlile" "J Liao" "Y Luo" "JW Hanrahan" "D Zhang" "SM Anjos" "DY Thomas"

CID is 5212
synonyms found at PubChem are:
sildenafil, 139755-83-2, Revatio, VIAGRA, Sildenafil [INN:BAN], UK-92480, UNII-3M7OB98Y7H, Aphrodil (TN), Sildenafil (INN), UK-92,480-10, C22H30N6O4S, HSDB 7305, CHEMBL192, 3M7OB98Y7H, CHEBI:9139, UK 92480-10, 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine, BNRNXUUZRGQAQC-UHFFFAOYSA-N, Caverta, 5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one, NCX-911, Revatio (TN), Viagra (TN), 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, Piperazine, 1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-, SMR000752512, 171599-83-0 (citrate), SR-05000001934, NCGC00159496-02, mysildecard, Aphrodil, Vizarsin, Rhucin, Sildenafil#, 1udt, 1xos, 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, 5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo(4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, Rhucin (TN), Spectrum_001555, SpecPlus_000798, AC1L1JUI, Spectrum2_001648, Spectrum3_001892, Spectrum4_000586, Spectrum5_001508, D08KTT, D0Z7ZM, Cambridge id 7030299, SCHEMBL1895, BSPBio_003424, KBioGR_001052, KBioSS_002035, MLS001240224, MLS001304737, MLS006011565, BIDD:GT0352, DivK1c_006894, SPECTRUM1504099, SPBio_001775, GTPL4743, SCHEMBL5795456, SCHEMBL8100377, Jsp002373, DTXSID6023579, BDBM14390, KBio1_001838, KBio2_002035, KBio2_004603, KBio2_007171, KBio3_002927, KS-00000XMX, 2h42, MolPort-002-885-861, HMS1684K08, HMS1922B19, HMS2089M12, HMS2093O17, HMS2233L22, HMS3372N07, HMS3715P17, Sildenafil 1.0 mg/ml in Methanol, ACT02662, BCP05337, AC-938, CCG-21806, CCG-39076, s4684, STL483201, STL483720, ZINC19796168, AKOS008901403, AKOS025397193, CS-1577, DB00203, MCULE-2481702478, NCGC00095099-01, NCGC00095099-02, NCGC00095099-03, NCGC00095099-04, NCGC00370976-03, 5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one, AN-15436, AS-48884, BAS 04213629, BC202768, HY-15025, M901, SC-83326, SMR004703325, SBI-0051920.P002, AB0015440, LS-111655, FT-0601554, C07259, D08514, W-2194, AB00052444-02, AB00052444-03, AB00052444_04, AB00052444_05, 755S832, SR-01000504734, I06-0023, J-007309, SR-01000504734-1, SR-05000001934-1, SR-05000001934-2, BRD-K50128260-001-01-6, BRD-K79759585-001-02-1, BRD-K79759585-048-01-4, 4-((4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydr, Z1522567175, Sildenafil solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one (Sildenafil or Viagra), 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one(Sildenafil), 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-n-propyl-1.6-dihydro-7H-pyrazolo[4,3-d]Pyrimidin-7-one, 5-[2-ethoxy-5-(4-methylpiperazine-1-sulfonyl)phenyl]-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one, 5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one

ID: 14

InChIKey: FFBDFADSZUINTG-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3CCCC3

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function inconsistent assignment
Order of interaction unknown
subcellular compartment unknown

reference list:

"A Tsopmo" "JD Connolly" "CP Ndi" "JL Teem" "P Tane" "AC deCarvalho" "J Ayafor"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"F Becq" "C Folli" "L Romio" "JM Vierfond" "Y Mettey" "O Zegarra-Moran" "P Fanen" "G Cabrini" "E Caci" "LJ Galietta"

CID is 1329
synonyms found at PubChem are:
8-Cyclopentyl-1,3-dipropylxanthine, DPCPX, 102146-07-6, 8-cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione, 1,3-Dpcpx, 1,3-dipropyl-8-cyclopentylxanthine, PD-116,948, PD-116948, GNF-PF-2224, UNII-9PTP4FOI9E, dipropylcyclopentylxanthine, 9PTP4FOI9E, CHEMBL183, MLS000069347, 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purin-2,6-dione, CHEBI:73282, 8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione, SMR000058434, DPCPX, 1,3-Dipropyl-8-cyclopentylxanthine, 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX], 8-cyclopentyl-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione, 8-Cyclopentyl-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-1,3-dipropyl-, PD 116948, Spectrum_000271, Tocris-0439, Opera_ID_160, Lopac-C-101, Spectrum2_001808, Spectrum3_001073, Spectrum4_001228, Spectrum5_001887, [DPCPX], D0K0OT, D0OW4Q, AC1L1B8K, Lopac0_000381, BSPBio_002686, GTPL386, KBioGR_001696, KBioSS_000751, MLS001076525, DivK1c_000177, SCHEMBL382422, SPECTRUM2300063, SPBio_001795, SCHEMBL1094807, SCHEMBL12648692, BCBcMAP01_000212, BDBM21173, CTK8B4471, HMS500I19, KBio1_000177, KBio2_000751, KBio2_003319, KBio2_005887, KBio3_001906, DTXSID50144706, OR9885T, FFBDFADSZUINTG-UHFFFAOYSA-N, MolPort-003-666-763, NINDS_000177, HMS2235C14, HMS3261M03, HMS3266O21, HMS3369D05, ZINC3977757, ZX-AT022179, DPCPX; PD 116,948, Tox21_500381, ANW-45129, CCG-39732, PDSP1_000448, PDSP1_001208, PDSP2_000446, PDSP2_001192, AKOS015900114, AKOS024458134, CCG-221685, DB12946, EX-3308, LP00381, VZ31021, IDI1_000177, KS-0000186U, NCGC00015177-01, NCGC00015177-02, NCGC00015177-03, NCGC00015177-04, NCGC00015177-05, NCGC00015177-06, NCGC00015177-07, NCGC00015177-08, NCGC00015177-09, NCGC00015177-10, NCGC00015177-11, NCGC00023294-02, NCGC00023294-04, NCGC00023294-05, NCGC00023294-06, NCGC00023294-07, NCGC00261066-01, AJ-47554, AK-88727, CC-23366, KB-53263, PD116948, SC-91856, 8-Cyclopentyl-1,3-dipropylxanthine, solid, AX8008808, LS-126534, ST2406601, B6305, EU-0100381, FT-0621530, X8593, C13709, C-18978, L000233, SR-01000003000, SR-01000075202, SR-01000003000-2, SR-01000075202-1, W-200660, BRD-K01824921-001-02-9, BRD-K01824921-001-10-2, I14-10012, 8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H);-dione, 8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

ID: 15

InChIKey: FLJBLCAZPFDCPE-UHFFFAOYSA-O
SMILES: C1=CC2=CC(=O)C3=C([NH+]2C=C1)C(=CC=C3)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function inconsistent assignment
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"F Becq" "S Noël" "C Rogier" "L Dannhoffer" "H DeJonge" "Y Mettey" "PO Strale" "M Wilke"

"F Becq" "A Vella" "V Bezzerri" "R Gambari" "Y Mettey" "E Nicolis" "M Colombatti" "BM Assael" "M Borgatti" "G Cabrini" "I Mancini" "MC Dechecchi"

"F Becq" "C Folli" "L Romio" "JM Vierfond" "Y Mettey" "O Zegarra-Moran" "P Fanen" "G Cabrini" "E Caci" "LJ Galietta"

CID is 9795308
synonyms found at PubChem are:
CHEMBL175225, SCHEMBL5738619, CHEMBL1181524, BDBM50139822, 10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chloride, MPB-07

ID: 16

InChIKey: JWZZKOKVBUJMES-UHFFFAOYSA-N
SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O

biological descriptors:

CFTR relevance: stimulates Cl- conductance as agonist of β2 adrenergic receptor

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

"T Leal" "C Bouckaert" "A Capron" "B Dhooghe" "P Wallemacq" "S Noel"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

"AM Van Heeckeren" "ML Drumm" "RC Boucher" "JR Riordan" "A Mengos" "M Gentzsch" "MR Knowles" "SH Randell" "SE Gabriel" "BR Grubb"

CID is 3779
synonyms found at PubChem are:
isoproterenol, Isoprenaline, Isoprenalin, Norisodrine, Novodrin, Isopropydrin, Isopropylarterenol, Asiprenol, Assiprenol, Bellasthman, Respifral, Aludrin, Aludrine, Asmalar, Isadrine, N-Isopropylnoradrenaline, Bronkephrine, Isonorene, Isopropyladrenaline, Lomupren, Neodrenal, Proternol, N-Isopropylnorepinephrine, Isopropylnorepinephrine, 7683-59-2, neo-Epinine, Isonorin, Isorenin, Saventrine, Isopropylnoradrenaline, Isopropyl noradrenaline, Racemic isoprenaline, dl-Isadrine, Isuprel, Racemic isoproterenol, (+-)-Isoproterenol, Vapo-N-iso, Epinephrine isopropyl homolog, Isoprenalinum, Isoproterenolum, Aleudrine, Isupren, (+-)-Isoprenaline, dl-Ipr, Isoprenalina, Isadrin, Isoproterenol [JAN], Dihydroxyphenylethanolisopropylamine, WIN 5162, DL(+-)-Isoproterenol, Medihaler-ISO, dl-Isopropylnoradrenaline, DL-Isopropylnorepinephrine, dl-N-Isopropylnoradrenaline, Isoprenalinum [INN-Latin], Isoprenalina [INN-Spanish], Isoproterenol Chloride, 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol, ICI 46399, l-Isoproterenol, d-Isoprenaline, d-Isoproterenol, alpha-(Isopropylaminomethyl)protocatechuyl alcohol, Isuprel Mistometer, N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine, (S)-Isoproterenol, (+)-Isoprenaline, d-Isopropylarterenol, Aleudrin, 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol, Isoprenaline (INN), ISOPROP, CCRIS 3081, 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol, l-Isopropylnoradrenaline, NSC 9975, EINECS 231-687-7, NSC 33791, (S)-(+)-Isoproterenol, Isoproterenol sulfate, Isopropylaminomethyl-3,4-dihydroxyphenyl carbinol, CHEMBL434, d-N-Isopropylnorepinephrine, 1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, BRN 2213857, 3,4-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol, 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol, CHEBI:64317, 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, JWZZKOKVBUJMES-UHFFFAOYSA-N, (S)-Isoprenaline, Isopropylaminomethyl(3,4-dihydroxyphenyl)carbinol, NSC33791, (+)-Isoproterenol, Isoprenaline [INN], Protocatechuyl alcohol, alpha-(isopropylaminomethyl)-, DL-ISOPROTERENOL, NCGC00015558-06, 3,4-Dihydroxy-.alpha.-(isopropylaminomethyl)-benzyl alcohol, Protocatechuyl alcohol,-, Isoprenaline sulfate, Isuprel (TN), DSSTox_CID_3175, 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (+-)-, BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-, (+-)-, DSSTox_RID_76904, DSSTox_GSID_23175, 149-53-1, .alpha.-(Isopropylaminomoethyl)protocatechuyl alcohol, 4-(1-Hydroxy-2(isopropylamino)ethyl)-benzene 1,2-diol, 4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol, 3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol, WLN: QR BQ DYQ1MY1&1, 3,4-Dihydroxy-.alpha.-[(isopropylamino)methyl]benzyl alcohol, 4-{1-hydroxy-2-[(1-methylethyl)amino]ethyl}benzene-1,2-diol, Benzyl alcohol, 3,4-dihydroxy-alpha-((isopropylamino)methyl)-, CAS-7683-59-2, 1, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, 4-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol, 4-{1-hydroxy-2-[(methylethyl)amino]ethyl}benzene-1,2-diol, Benzyl alcohol,4-dihydroxy-.alpha.-[(isopropylamino)methyl]-, Isoproterenol-l, Isoproterenol;, Isoprenalinesulphate, Isoproterenol (-), Isoproterenol,(+), DL-isoprenaline HCl, ISOPROTERONOL, Isuprel (Salt/Mix), Izadrin (Salt/Mix), Euspiran (Salt/Mix), (+/-)-isoprenaline, (+/-)-isoproterenol, Spectrum_000949, AC1L1GOZ, AC1Q1QBS, 6700-39-6, Prestwick0_001097, Prestwick1_001097, Prestwick2_001097, Spectrum2_001061, Spectrum3_000474, Spectrum4_000024, Spectrum5_000880, (.+/-.)-Isoprenaline, (.+/-.)-Isoproterenol, D0I8FI, D0IF0C, D0P1IS, SCHEMBL4165, DL(.+/-.)-Isoproterenol, Lopac0_000711, Oprea1_009434, BSPBio_002208, GTPL536, KBioGR_000427, KBioSS_001429, 3-13-00-02387 (Beilstein Handbook Reference), DivK1c_000894, SPBio_001042, SPBio_003057, SGCUT00015, BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-, (+)-, DTXSID4023175, BDBM25392, KBio1_000894, KBio2_001429, KBio2_003997, KBio2_006565, KBio3_001428, NSC9975, NINDS_000894, HMS2089A12, BCP09043, NSC-9975, to_000062, (A+/-)-Isoproterenol hydrochloride, Tox21_110172, AS1409, NSC-33791, PDSP1_001425, PDSP2_001409, SBB005855, AKOS015913894, Tox21_110172_1, API0006523, CCG-204727, CCG-204796, DB01064, MCULE-6061231962, IDI1_000894, NCGC00015558-04, NCGC00015558-05, NCGC00015558-07, NCGC00015558-08, NCGC00015558-09, NCGC00015558-10, NCGC00015558-11, NCGC00015558-12, NCGC00015558-14, NCGC00016665-02, NCGC00025274-03, NCGC00025274-04, NCGC00162220-01, LS-42866, LS-42868, LS-42869, ST077771, SBI-0050689.P004, FT-0724367, C07056, D08090, EN300-148243, AB00053487-09, AB00053487-10, AB00053487_11, AB00053487_12, 683I592, alpha-(Isopropylaminomoethyl)protocatechuyl alcohol, L000936, .alpha.-(Isopropylaminomethyl)protocatechuyl alcohol, I14-45263, Protocatechuyl alcohol,.alpha.-(isopropylamino-methyl),-, 3,4-dihydroxy-alpha-[(isopropylamino)methyl]-benzyl alcohol, 4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol #, N-Isopropyl-.beta.-dihydroxyphenyl-.beta.-hydroxyethylamine, 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride, 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2, Benzyl alcohol, 3,4-dihydroxy-.alpha.-((isopropylamino)methyl)-, 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)- (9CI), 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-(9CI), 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (S)-, 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (S)-(9CI), 46388-38-9

ID: 17

InChIKey: LUKBXSAWLPMMSZ-UPHRSURJSA-N
SMILES: C1=CC(=CC=C1/C=C\C2=CC(=CC(=C2)O)O)O

biological descriptors:

CFTR relevance: CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment Apical membrane & subapical compartment

reference list:

"S Moriceau" "M Kelly" "G Planelles" "J Colas" "J Fritsch" "N Hamdaoui" "M Baudoin-Legros" "A Aissat" "A Edelman" "DL Vieu"

"Y Jai" "K Shah" "NA Bradbury" "RJ Bridges"

"BA Woodworth" "DF Skinner" "CM McNicholas" "AC Blount" "JC Kappes" "M Chestnut" "S Zhang" "EJ Sorscher"

CID is 1548910
synonyms found at PubChem are:
cis-resveratrol, (Z)-resveratrol, 61434-67-1, Cis resveratrol, Resveratrol, (Z)-, UNII-AUA0K06FSB, cis-3,4',5-trihydroxystilbene, AUA0K06FSB, CHEMBL87333, CHEBI:36002, 5-[(Z)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol, 5-[(Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, 5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol, 1,3-Benzenediol, 5-((1Z)-2-(4-hydroxyphenyl)ethenyl)-, Resveratrol (Z)-form [MI], Z-Resveratrol, Resveratrol, Z-, NCGC00015894-02, CAS-501-36-0, Tocris-1418, AC1LU7HY, Lopac-R-5010, cis-3,4,5-Trihydroxystilbene, SCHEMBL1931746, cis-3,5,4'-trihydroxystilbene, LUKBXSAWLPMMSZ-UPHRSURJSA-, (Z)-3,4',5-trihydroxystilbene, (Z)-3,5,4'-trihydroxystilbene, 4q93, MolPort-003-850-143, TNP00294, 1684AH, BDBM50131698, ZINC12353732, AKOS025395422, NCGC00015894-01, NCGC00017352-01, NCGC00017352-02, NCGC00017352-03, NCGC00017352-04, NCGC00024003-02, AC-24235, CJ-13797, DB-072954, 434C671, I14-7425, Z-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol, cis-5-[2-(4-Hydroxyphenyl)ethenyl]benzene-1,3-diol, 05F9DB2A-D7E6-4063-8E5B-F7842CF74A5E, 5-[(1Z)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol, InChI=1/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1-

ID: 18

InChIKey: REFJWTPEDVJJIY-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

"AD Floyd" "PL Zeitlin" "E Kwon" "M Lim" "K McKenzie"

"SM Rowe" "BA Woodworth" "D Schuster" "C Azbell" "S Zhang" "N Smith" "EJ Sorscher"

CID is 5280343
synonyms found at PubChem are:
quercetin, 117-39-5, Meletin, Sophoretin, Quercetine, Xanthaurine, Quercetol, Quercitin, Quertine, 3,3',4',5,7-Pentahydroxyflavone, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one, Flavin meletin, Cyanidelonon 1522, T-Gelb bzw. grun 1, 3,5,7,3',4'-Pentahydroxyflavone, C.I. Natural Yellow 10, Quercetin content, Kvercetin, Quertin, C.I. Natural red 1, Kvercetin [Czech], Natural Yellow 10, C.I. 75670, CI Natural Yellow 10, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, 3',4',5,7-Tetrahydroxyflavan-3-ol, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, C.I. Natural yellow 10 & 13, CCRIS 1639, HSDB 3529, Flavone, 3,3',4',5,7-pentahydroxy-, NCI-C60106, UNII-9IKM0I5T1E, NSC 9219, 3',4',5,7-tetrahydroxyflavon-3-ol, 3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-on, Cyanidenolon 1522, CHEBI:16243, AI3-26018, NSC9219, CHEMBL50, EINECS 204-187-1, MixCom3_000183, BRN 0317313, C.I . natural yellow 10, 9IKM0I5T1E, CI 75670, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one, 2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chromen-4-one, REFJWTPEDVJJIY-UHFFFAOYSA-N, KUC104418N, KUC107684N, 3,3',4,5,7-Pentahydroxyflavone, LIM-5662, LNS-5662, NSC-9219, TNP00070, TNP00089, KSC-23-76, KSC-10-126, P0042, DSSTox_CID_1218, Q 0125, DSSTox_RID_76017, DSSTox_GSID_21218, 74893-81-5, QUE, CU-01000012502-3, Q-200333, BRD9794, 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one, BRD-9794, CAS-117-39-5, NSC57655, NSC58588, SR-01000076098, Ritacetin, Quer, 4dfu, 4mra, Quercetin_sathishkumar, Quercetin (Sophoretin), Quercetin - Sophoretin, Spectrum_000124, Tocris-1125, 3cf8, AC1NQWX8, BiomolKI_000062, 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, zirconium(2+) salt (1:1), Maybridge1_008992, Prestwick0_000507, Prestwick1_000507, Prestwick2_000507, Prestwick3_000507, Spectrum2_000059, Spectrum3_000642, Spectrum4_000807, Spectrum5_001389, Lopac-Q-0125, C.I. natural yellow 13, BiomolKI2_000068, D0K8KX, Enicostemma Littorale Blume, UPCMLD-DP081, NCIOpen2_007628, NCIOpen2_007882, BIDD:PXR0007, Lopac0_000999, SCHEMBL19723, BSPBio_000433, BSPBio_001068, BSPBio_002243, KBioGR_000408, KBioGR_001293, KBioSS_000408, KBioSS_000584, 5-18-05-00494 (Beilstein Handbook Reference), KSC497C4F, MLS006011766, BIDD:ER0315, DivK1c_000485, SCHEMBL219729, SPECTRUM1500672, SPBio_000217, SPBio_002354, AC1Q795S, AC1Q795T, BDBM7460, BPBio1_000477, GTPL5346, MEGxp0_000381, SGCUT00001, 3,4',5,7-Pentahydroxyflavone, DTXSID4021218, UPCMLD-DP081:001, ACon1_000560, CTK3J7142, HMS501I07, KBio1_000485, KBio2_000408, KBio2_000584, KBio2_002976, KBio2_003152, KBio2_005544, KBio2_005720, KBio3_000775, KBio3_000776, KBio3_001463, 3,7,3',4'-Pentahydroxyflavone, MolPort-001-740-557, NINDS_000485, 3',5,7-Tetrahydroxyflavan-3-ol, Bio1_000369, Bio1_000858, Bio1_001347, Bio2_000374, Bio2_000854, HMS1362F09, HMS1792F09, HMS1923O19, HMS1990F09, HMS3263G19, HMS3267M12, HMS3649D04, HMS3656C15, to_000078, ZINC3869685, 3,5,7,3',4'-Pentahydroxyflavon, Tox21_202308, Tox21_300285, Tox21_500999, ANW-73134, BBL005513, BS0155, CCG-40054, CQ0011, Flavone,3',4',5,7-pentahydroxy-, GP9232, LMPK12110004, LS-589, MFCD00006828, NSC324608, Quercetin solution, 20 mM in DMSO, s2391, SBB012521, STK365650, Quercetin, >=95% (HPLC), solid, 3,4',5,5',7-pentahydroxy-Flavone, AKOS000511724, CS-3981, DB04216, DS-3416, EBD2197934, LP00999, MCULE-2433372790, NUT0000107, RTX-012622, IDI1_000485, IDI1_002129, KS-0000021G, SMP1_000252, Flavone, 3,4',5,5',7-pentahydroxy-, NCGC00015870-01, NCGC00015870-02, NCGC00015870-03, NCGC00015870-05, NCGC00015870-06, NCGC00015870-07, NCGC00015870-08, NCGC00015870-09, NCGC00015870-10, NCGC00015870-11, NCGC00015870-12, NCGC00015870-13, NCGC00015870-14, NCGC00015870-15, NCGC00015870-16, NCGC00015870-17, NCGC00015870-18, NCGC00015870-19, NCGC00015870-21, NCGC00015870-22, NCGC00015870-23, NCGC00015870-24, NCGC00025016-01, NCGC00025016-02, NCGC00025016-03, NCGC00025016-04, NCGC00025016-05, NCGC00025016-06, NCGC00025016-07, NCGC00025016-08, NCGC00168962-01, NCGC00168962-02, NCGC00168962-03, NCGC00168962-04, NCGC00254218-01, NCGC00259857-01, NCGC00261684-01, 4CN-0923, AC-19596, AC-29756, AJ-46321, AK106169, AN-22768, BAS 00649429, CJ-10980, HY-18085, KB-66753, LS-69030, NCI60_042036, S295, SC-25667, SMR000112559, ST024706, ST057237, Quercetin, Sophoretin, Meletin, Quercetine, AX8030401, KB-221421, EU-0100999, FT-0603318, FT-0655108, N1841, Q0025, ST24039236, Quercetin, disposable screening library format, Quercetin; 3,3',4',5,7-Pentahydroxyflavone, 17Q395, A-8821, C00389, K00029, S00057, WLN: T66 BO EVJ CR CQ DQ & DQ GQ IQ, SR-01000076098-1, SR-01000076098-3, SR-01000076098-7, SR-01000076098-8, BRD-K97399794-001-02-1, BRD-K97399794-001-07-0, BRD-K97399794-001-09-6, BRD-K97399794-001-11-2, BRD-K97399794-335-03-1, SR-01000076098-11, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate, 3,3',4',5,7-pentahydroxyflavone solution, 20 mM in DMSO, A1784/0075599, 49643640-FD4C-4B93-BD28-0D7C2021CC52, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one #, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one solution, 20 mM in DMSO, 73123-10-1

ID: 19

InChIKey: RFDOKDAIYRJYJJ-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C=C(NN2)C3=CC=CC=C3)C(=O)C=C1

biological descriptors:

CFTR relevance: CFTR modulators

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"SM Rowe" "BA Woodworth" "SB Hicks" "D Skinner" "BT Conger" "S Zhang" "EJ Sorscher"

"CE Bear" "LJ Huan" "L Wellhauser" "P Kim Chiaw" "M Ramjeesingh"

CID is 6742696
synonyms found at PubChem are:
VRT-532, VRT532, VRT 532, 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, Cambridge id 5478102, AC1OA052, GTPL4341, CTK8I5138, ZINC4576484, 4-methyl-6-(5-phenyl-1,2-dihydropyrazol-3-ylidene)cyclohexa-2,4-dien-1-one

ID: 20

InChIKey: UFSKUSARDNFIRC-UHFFFAOYSA-N
SMILES: CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"RW Hofland" "AC de Kiviet" "HGM Arets" "MA Kruijswijk" "S Schotman" "CK van der Ent" "S Michel" "KM de Winter-de Groot" "HGM Heijerman" "MMM van Oirschot-van de Ven" "BL Aalbers"

"F Becq" "M Jollivet Souchet" "R Ferru-Clément" "C Boinot"

"CM Farinha" "AM Matos" "FR Pinto" "P Jordan" "P Matos" "CA Loureiro" "JD Santos"

"G Cui" "JS Hong" "BB Stauffer" "A Rab" "NA McCarty" "BR Imhoff" "EJ Sorscher"

"Y Chen" "ZW Dong" "YC Ruan" "LL Tsang" "HC Chan" "YZ Peng" "T Zhou" "J Chen"

"C Ottmann" "RM de Vries" "DS van Scheppingen" "CV Lam" "GW Carlile" "L Brunsveld" "LM Stevers" "FA Meijer" "LG Milroy" "SF Leysen" "DY Thomas"

"H Dang" "R Schlegel" "X Liu" "C Cho" "SE Boyles" "C Cheluvaraju" "NL Quinney" "M Gentzsch" "SH Randell" "IG Chaudhry"

"JC Fares" "A Meissner" "M Husain" "H Wan" "SS Bolz" "A Adel" "M Sumiyoshi" "D Lidington" "F Matthes" "M Sauvé" "R Aschar-Sobbi" "RL Macdonald" "A Momen" "L Vanherle" "PH Backx" "FE Uhl" "JT Kroetsch" "DD Dinh" "FA Malik" "SP Heximer" "H Zhang" "WD Foltz"

"K McBennett" "SB Donnola" "CA Flask" "B Kaminski" "M O'Riordan" "R Gubitosi-Klug" "TJ Sferra" "K Kutney"

"F Becq" "L Froux" "E Sage" "C Coraux"

"R Robert" "GW Carlile" "J Goepp" "Y Luo" "E Matthes" "JW Hanrahan" "K Dejgaard" "A Billet" "DY Thomas"

"S Hadida" "M Miller" "JJ Wine" "M Ashlock" "F Van Goor" "JH Stack" "ER Olson" "PA Negulescu" "KS Straley" "B Burton" "CJ Decker" "J McCartney" "PD Grootenhuis" "RA Frizzell"

"K Montemayor" "AT Claudio" "NE West" "S Carson" "MS Christianson" "N Lechtzin"

CID is 16678941
synonyms found at PubChem are:
936727-05-8, Lumacaftor, VX-809, VX 809, VX809, VRT-826809, 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid, UNII-EGP8L81APK, VRT 826809, EGP8L81APK, 3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-benzoicacid, 3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-benzoic acid, 3-(6-[[1-(2,2-DIFLUORO-BENZO[1,3]DIOXOL-5-YL)-CYCLOPROPANECARBONYL]-AMINO]-3-METHYL-PYRIDIN-2-YL)-BENZOIC ACID, 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid, 3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-be, 3-(6-{[1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)benzoic acid, 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methylpyridin-2-yl]benzoic acid, Lumacaftor [USAN:INN], Lumacaftor (USAN), PubChem22450, MLS006011120, SCHEMBL377028, Lumacaftor(vx-809 vx809), GTPL7481, CHEMBL2103870, CHEBI:90951, CTK8B5597, AOB2051, DTXSID30239523, EX-A178, C24H18F2N2O5, MolPort-009-198-874, UFSKUSARDNFIRC-UHFFFAOYSA-N, HMS3655E05, BCP02305, ABP000707, ANW-49250, s1565, VX-809/VX809, ZINC64033452, AKOS015920205, API0007686, CS-0479, DB09280, PB19466, QC-7245, NCGC00346550-01, NCGC00346550-05, 3-(6-(1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamido)-3-methylpyridin-2-yl)benzoic acid, 4CA-0760, AC-23172, AK-36922, AN-16986, AS-31756, BC660192, Benzoic acid, 3-(6-(((1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl)carbonyl)amino)-3-methyl-2-pyridinyl)-, BR-36922, EN002684, HY-13262, KB-81477, SC-95543, SMR004702901, AB0008169, AJ-114588, AX8160252, TC-137995, FT-0757817, ST24028315, W9631, A25628, D10134, S-5955, J-690399, VX809, VX 809, 936727-05-8, 1220975-12-1, 3-(6-([1-(2,2-DIFLUORO-2H-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE]AMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID, 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid, 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-3-methylpyridin-2-yl)benzoic acid, 3-(6-{[1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)cyclopropanecarbonyl]amino}-3-methyl-pyridin-2-yl)benzoi, 3-(6-{[1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)cyclopropanecarbonyl]amino}-3-methyl-pyridin-2-yl)benzoic acid, 3-[6-[[[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid VX 809 Lumacaftor, 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methyl-2-pyridyl]benzoic acid, 3-{6-[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid, 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid

ID: 21

InChIKey: WAEXFXRVDQXREF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO

biological descriptors:

CFTR relevance: CFTR proteostasis regulator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"F Becq" "M Jollivet Souchet" "R Ferru-Clément" "C Boinot"

"W Kellner" "D Herman" "Y Matsumura" "PJ Thomas" "T Okiyoneda" "JR Riordan" "WE Balch" "M Gentzsch" "A Schmidt" "JW Kelly" "WR Skach" "EJ Sorscher" "GL Lukacs" "JM Gottesfeld" "JR_3rd Yates" "B Hoch" "AP Rodrigues" "DM Hutt" "RA Frizzell" "G Manning" "J Matteson" "S Noel" "JM Pilewski"

"AI Esposito" "U Pfeffer" "E Sondo" "E Caci" "LJ Galietta" "V Tomati" "N Pedemonte"

CID is 5311
synonyms found at PubChem are:
Vorinostat, 149647-78-9, SAHA, suberoylanilide hydroxamic acid, Zolinza, N-hydroxy-N'-phenyloctanediamide, Suberanilohydroxamic acid, N1-hydroxy-N8-phenyloctanediamide, SAHA cpd, MK-0683, MK0683, Vorinostat [USAN], Octanediamide, N-hydroxy-N'-phenyl-, CCRIS 8456, Vorinostat (SAHA, MK0683), N-Hyrdroxy-N'-phenyloctanediamide, Vorinostat MSD, UNII-58IFB293JI, Zolinza (TN), OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, SHH, N'-hydroxy-N-phenyloctanediamide, CHEMBL98, Vorinostat (JAN/USAN), 58IFB293JI, SKI390, CHEBI:45716, WAEXFXRVDQXREF-UHFFFAOYSA-N, WIN64652, NSC701852, SAHA, Suberoylanilide hydroxamic acid, NSC-701852, NCGC00168085-01, NCGC00168085-02, SW-064652, 8-(hydroxyamino)-8-oxo-N-phenyl-octanamide, Zolinza (TN) (Merck), DSSTox_CID_21133, DSSTox_RID_79632, DSSTox_GSID_41133, N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide, SMR000486344, NHNPODA, CAS-149647-78-9, SR-05000000373, Vorinostat [USAN:INN], vorinostatum, HSDB 7930, 4lxz, N-Hydroxy-N'-phenyl octanediamide, Zolinza; SAHA, Vorinostat (SAHA), Vorinostat - SAHA, MK 0683, 1zz1, Merck brand of Vorinostat, cc-95, D0E7PQ, AC1L1K2K, cid_5311, SCHEMBL9018, Vorinostat (HDAC inhibitor), Suberoylanilidehydroxamic Acid, MLS001065855, MLS006011941, GTPL6852, Zolinza, MK-0683, SAHA, DTXSID6041133, BDBM19149, CTK8B4125, AOB6083, n-hydroxy-n'-phenyl-octanediamide, QCR-121, SUBERANILOHYDROXAMINIC ACID, SYN3006, 1t69, MolPort-003-850-293, N-hydroxy-N''-phenyloctanediamide, BCPP000018, HMS2219L20, HMS3264D20, HMS3327C12, HMS3650D09, HMS3654G11, HMS3715E22, Pharmakon1600-01502267, BCP01858, KS-00000H3B, N1-hydroxy-N8-phenyl-octanediamide, SAHA, >=98% (HPLC), Vorinostat,SAHA,Zolinza,MK-0683, ZINC1543873, Tox21_112605, Tox21_113623, Vorinostat,CAS:149647-78-9, ANW-43951, MFCD00945317, NSC748799, NSC759852, Octanediamide, N1-hydroxy-N8-phenyl, s1047, SK1390, AKOS015966648, Octanediamide, N1-hydroxy-N8-phenyl-, Tox21_112605_1, AC-1923, AN-5256, CCG-208659, CS-0589, DB02546, DG-0025, MCULE-4234367506, NSC-748799, NSC-759852, RP29421, Suberoylanilide hydroxamic acid (SAHA), NCGC00168085-03, NCGC00168085-04, NCGC00168085-05, NCGC00168085-13, BC677687, BP-30216, HY-10221, KB-60639, SC-20040, AB0009911, LS-186548, LS-186997, LS-187780, RT-015807, AM20030018, FT-0082592, FT-0650593, D06320, K-4759, AB00375377-07, AB00375377-08, AB00375377-09, AB01644613_25, 647S789, P111011, Vorinostat, SAHA, suberoylanilide hydroxamic acid, SR-05000000373-2, SR-05000000373-6, SR-05000000373-8, W-201327, BRD-K81418486-001-01-2, BRD-K81418486-001-10-3, BRD-K81418486-001-12-9, BRD-K81418486-001-13-7, BRD-K81418486-001-17-8, BRD-K81418486-001-18-6, Z1541632802

ID: 22

InChIKey: XWSYQZVZZMFGFW-UHFFFAOYSA-N
SMILES: CC1=NC(=NC2=C1C=C(C=C2)OC)NC3=NC(=O)C=C(N3)CSC4=NC5=CC=CC=C5N4

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

"JP Clancy" "K Varga" "J Fortenberry" "LC Pyle" "J Collawn" "M Mazur" "EJ Sorscher" "A Jurkevante" "SM Rowe" "B Woodworth" "L Fan" "PA Sloane" "J Fulton" "Y Li"

"Y Wang" "MC Bartlett" "DM Clarke" "TW Loo"

CID is 1386410
synonyms found at PubChem are:
MLS000587783, STK562693, 362000-44-0, SMR000211743, 6-(1H-Benzoimidazol-2-ylsulfanylmethyl)-2-(6-methoxy-4-methyl-quinazolin-2-ylamino)-pyrimidin-4-ol, 6-(1H-benzimidazol-2-ylsulfanylmethyl)-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]-1H-pyrimidin-4-one, 6-[(1H-benzimidazol-2-ylsulfanyl)methyl]-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]pyrimidin-4-ol, Corr-3a, AC1LR1AE, Oprea1_443670, Oprea1_685675, SCHEMBL837686, CHEMBL1374384, BDBM68023, cid_1386410, CTK8I4173, DTXSID30362587, MolPort-000-717-537, MolPort-002-553-491, HMS2527M03, STK017630, ZINC15987756, AKOS005378152, AKOS005488273, MCULE-9390583364, KB-44178, SR-01000450464, SR-01000450464-1, 4-pyrimidinol, 6-[(1H-benzimidazol-2-ylthio)methyl]-2-[(6-methoxy-4-methyl-2-quinazolinyl)amino]-, 6-(1H-benzimidazol-2-ylsulfanylmethyl)-2-[(6-methoxy-4-methyl-quinazolin-2-yl)amino]-1H-pyrimidin-4-one, 6-(1H-Benzoimidazol-2-ylsulfanylmethyl)-2-(6-methoxy-4-methylquinazolin-2-ylamino)pyrimidin-4-ol, 6-[(1H-benzimidazol-2-ylsulfanyl)methyl]-2-[(6-methoxy-4-methylquinazolin-2-yl)amino]pyrimidin-4(3H)-one, 6-[(1H-benzimidazol-2-ylthio)methyl]-2-[(6-methoxy-4-methyl-2-quinazolinyl)amino]-1H-pyrimidin-4-one, 6-[(1H-benzimidazol-2-ylthio)methyl]-2-[(6-methoxy-4-methyl-quinazolin-2-yl)amino]-1H-pyrimidin-4-one

ID: 23

InChIKey: ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

biological descriptors:

CFTR relevance: CFTR Blocker

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

"KL Hamilton" "MJ Baker"

CID is 3488
synonyms found at PubChem are:
Glibenclamide, glyburide, 10238-21-8, Glybenclamide, Micronase, Diabeta, Glynase, Daonil, Euglucon, Maninil, Semi-daonil, Apo-Glibenclamide, Euglucon 5, Azuglucon, Bastiverit, Benclamin, Betanase, Duraglucon, Euglucan, Euglykon, Glibenil, Glucolon, Neogluconin, Orabetic, Prodiabet, Renabetic, Yuglucon, Dibelet, Gilemal, Glibens, Glibil, Glimel, Glimide, Humedia, Libanil, Suraben, Tiabet, Adiab, Glybenzcyclamide, Melix, Pira, Med-Glionil, Gewaglucon, Glibenbeta, Glibenclamida, Glibenclamidum, Glucohexal, Glucoremed, Hexaglucon, Lisaglucon, Normoglucon, Praeciglucon, Calabren, Cytagon, Euclamin, Glamide, Glibesyn, Glibetic, Gliboral, Glidiabet, Glisulin, Glitisol, Glubate, Glucobene, Glucomid, Glucoven, Glycomin, Lederglib, Miglucan, Debtan, Gliban, Gliben, Glibet, Glicem, Gluben, Glyben, Nadib, Sugril, Novo-Glyburide, Glibenclamid AL, Gen-Glybe, Norglicem 5, Betanese 5, Glibenclamid Fabra, Glibenclamid Basics, Glibenclamid-Cophar, Glibenclamid Heumann, Semi-Euglucon, Glibenclamid Genericon, Hemi-Daonil, Glibenclamid-Ratiopharm, Glibenclamidum [INN-Latin], Glibenclamida [INN-Spanish], Abbenclamide, HB 419, Diabiphage, Glibadone, Semi-Gliben-Puren N, GBN 5, Glibenclamid Riker M., Glyburide (micronized), Euglucon N, 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide, Micronized glyburide, Glyburide [USAN], UR 606, Glimidstata, Glycolande, Glycron, PresTab, Gluco-Tablimen, Dia-basan, UNII-SX6K58TVWC, 1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea, Gliben-Puren N, Micronase (TN), C23H28ClN3O5S, Glyburide (USP), HB-419, 1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, Diabeta (TN), Glynase (TN), Glibenclamid Riker M, 5-Chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide, U 26452, glyburide (glibenclamide), EINECS 233-570-6, HB-420, SX6K58TVWC, CHEMBL472, BRN 2230085, N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea, MLS000069721, CHEBI:5441, 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide, Urea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexyl-, Benzamide, 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-, NCGC00015467-11, SMR000058229, CAS-10238-21-8, 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, G 0639, Urea, 1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-, 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide, DSSTox_CID_17237, DSSTox_RID_79313, N-(4-(beta-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff, DSSTox_GSID_37237, U-26452, Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, W-108874, 1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, 1-{4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea;1-{4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea, GIBENCLAMIDE, SR-01000000196, Glyburide [USAN:USP], glicuformine, Delmide, HB419, HB420, Euglucon (TN), Glibenclamide,(S), 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide, GBM, Prestwick_569, Glibenclamide B.P., Daonil (TN), Glyburide (Diabeta), HB 420, Semi-Daonil (TN), Glibenclamide [INN], RP-1127, Spectrum_000250, Tocris-0911, Opera_ID_801, Prestwick0_000316, Prestwick1_000316, Prestwick2_000316, Prestwick3_000316, Spectrum2_001816, Spectrum3_001327, Spectrum4_001199, Spectrum5_001631, Lopac-G-0639, ACMC-20a66i, D05LYX, Probes1_000431, Probes2_000378, UPCMLD-DP006, AC1L1G1Q, Glibenclamide (JP15/INN), Glibenclamide (JP17/INN), CBiol_001790, Lopac0_000499, Oprea1_764617, SCHEMBL22009, BSPBio_000312, BSPBio_001351, BSPBio_003053, KBioGR_000071, KBioGR_001897, KBioSS_000071, KBioSS_000730, MLS001077262, BIDD:GT0239, DivK1c_000481, SPECTRUM2300229, SPBio_001831, SPBio_002531, AC1Q44V7, BPBio1_000344, GTPL2414, DTXSID0037237, UPCMLD-DP006:001, CTK8B7917, HMS501I03, KBio1_000481, KBio2_000071, KBio2_000730, KBio2_002639, KBio2_003298, KBio2_005207, KBio2_005866, KBio3_000141, KBio3_000142, KBio3_002273, AOB6214, SYN3026, Glybenclamide, >=99% (HPLC), MolPort-000-784-850, NINDS_000481, ZNNLBTZKUZBEKO-UHFFFAOYSA-N, Bio1_000076, Bio1_000565, Bio1_001054, Bio2_000071, Bio2_000551, HMS1361D13, HMS1568P14, HMS1791D13, HMS1922L08, HMS1989D13, HMS2089L06, HMS2093P04, HMS2095P14, HMS3259O12, HMS3261D19, HMS3267A15, HMS3402D13, HMS3428D15, HMS3651E17, HMS3712P14, Pharmakon1600-02300229, ZINC537805, BCP05327, Tox21_110158, Tox21_300758, Tox21_500499, ANW-58936, BDBM50012957, BG0207, CCG-39618, GP8701, HD 419, MFCD00056625, NSC759618, SBB057426, STK362992, AKOS001487495, Tox21_110158_1, BCP9000729, CS-1075, DB01016, KS-5326, LP00499, MCULE-2351642942, NC00566, NSC-759618, IDI1_000481, IDI1_033821, Glibenclamide 1.0 mg/ml in Acetonitrile, NCGC00015467-01, NCGC00015467-02, NCGC00015467-03, NCGC00015467-04, NCGC00015467-05, NCGC00015467-06, NCGC00015467-07, NCGC00015467-08, NCGC00015467-09, NCGC00015467-10, NCGC00015467-12, NCGC00015467-13, NCGC00015467-14, NCGC00015467-15, NCGC00015467-16, NCGC00015467-17, NCGC00015467-18, NCGC00015467-20, NCGC00015467-36, NCGC00016689-01, NCGC00023447-02, NCGC00023447-04, NCGC00023447-05, NCGC00023447-06, NCGC00023447-07, NCGC00023447-08, NCGC00023447-09, NCGC00023447-10, NCGC00023447-11, NCGC00023447-12, NCGC00254662-01, NCGC00261184-01, 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide, AJ-23371, AN-20367, CPD000058229, HY-15206, KB-73471, SAM002564212, SC-17437, ST024780, SBI-0050483.P003, AB0012611, AB2000243, Glyburide, meets USP testing specifications, LS-159295, RT-000122, AB00051949, EU-0100499, FT-0601608, G0382, S1716, A19539, C07022, D00336, J10021, W-5054, 78637-EP2270001A1, 78637-EP2270011A1, 78637-EP2272825A2, 78637-EP2272841A1, 78637-EP2275414A1, 78637-EP2287165A2, 78637-EP2287166A2, 78637-EP2292620A2, 78637-EP2298750A1, 78637-EP2298776A1, 78637-EP2298779A1, 78637-EP2301923A1, 78637-EP2301936A1, 78637-EP2305648A1, 78637-EP2308847A1, AB00051949-16, AB00051949-17, AB00051949_18, AB00051949_19, C-22898, I06-0716, SR-01000000196-2, SR-01000000196-4, SR-01000000196-5, SR-01000000196-6, SR-01000000196-8, U-26,452, BRD-K36927236-001-06-0, BRD-K36927236-001-17-7, Z277540138, Glybenclamide, European Pharmacopoeia (EP) Reference Standard, Glyburide, United States Pharmacopeia (USP) Reference Standard, 1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl urea, 5-Chloro-N-[4-(3-cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)-phenethyl)-2-methoxybenzamide, 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxy-benzamide, 5-chloro-N-[4-({[(cyclohexylamino)carbonyl]amino}sulfonyl)phenethyl]-2-methoxybenzamide, Glibenclamide for peak identification, European Pharmacopoeia (EP) Reference Standard, Glyburide (Glibenclamide), Pharmaceutical Secondary Standard; Certified Reference Material, N-(4-(.beta.-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N -cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N'-cyclohexylurea, N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N-cyclohexylurea, (5-chloro-2-methoxyphenyl)-N-[2-(4-{[(cyclohexylamino)carbonylamino]sulfonyl}p henyl)ethyl]carboxamide, 5-Chloro-N-(2-[4-(([(cyclohexylamino)carbonyl]amino)sulfonyl)phenyl]ethyl)-2-methoxybenzamide #, 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide, N-[(4-{2-[(5-chloro-2-methoxyphenyl)carbonylamino]ethyl}phenyl)sulfonyl](cyclo hexylamino)carboxamide

ID: 24

InChIKey: ZQSIJRDFPHDXIC-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 5281708
synonyms found at PubChem are:
daidzein, 486-66-8, 4',7-Dihydroxyisoflavone, Daidzeol, 7,4'-Dihydroxyisoflavone, 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Diadzein, 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-, 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one, 7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, UNII-6287WC5J2L, CCRIS 7600, K 251b, 4,7-Dihydroxyisoflavone, EINECS 207-635-4, BRN 0231523, CHEMBL8145, 4',7-Dihydroxy-iso-flavone, d-(+)-alpha-methylbenzylamine, 4′,7-Dihydroxyisoflavone, CHEBI:28197, ZQSIJRDFPHDXIC-UHFFFAOYSA-N, 6287WC5J2L, Daidzein,(S), 7-Hydroxy-3-(4-hydroxy-phenyl)-chromone, DSSTox_CID_2310, DSSTox_RID_76543, DSSTox_GSID_22310, Q-200924, CAS-486-66-8, SMR000326832, Daidzein (6CI), SR-01000075492, NPI 031E, PubChem9841, AC1NQYXY, Spectrum_000255, Tocris-1417, BiomolKI_000060, Spectrum2_000053, Spectrum3_000191, Spectrum4_001964, Spectrum5_000857, Lopac-D-7802, 4 ,7-Dihydroxyisoflavone, BiomolKI2_000066, D0N9CG, D0SY2M, UPCMLD-DP052, 4',7-dihydroxy isoflavone, 4',7-dihydroxy-Isoflavone, Lopac0_000412, Oprea1_182317, Oprea1_305345, SCHEMBL19814, BSPBio_001741, Daidzein, analytical standard, KBioGR_002432, KBioSS_000735, SPECTRUM200789, 5-18-04-00089 (Beilstein Handbook Reference), MLS000859973, MLS001304056, MLS006011853, BIDD:ER0120, DivK1c_001023, SPBio_000205, Daidzein, >=98%, synthetic, Isoflavone, 4',7-dihydroxy-, BIMB2005, BMK1-F12, GTPL2828, MEGxm0_000123, NPI-031E, d-(+)-alpha-methylbenzyl amine, DTXSID9022310, UPCMLD-DP052:001, ACon0_001477, ACon1_000543, BDBM23420, HMS503M07, K-251b, KBio1_001023, KBio2_000735, KBio2_003303, KBio2_005871, KBio3_001241, KS-00000MGD, AOB5524, OR1035T, 4',7-Dihydroxyisoflavone, 97%, MolPort-000-003-017, NINDS_001023, ZX-AFC000144, 7,4'-Dihydroxy-isoflavone (3a), HMS1922P18, HMS2233H24, HMS3261C06, HMS3267J04, HMS3370C03, HMS3468L18, HMS3649B20, HMS3655A18, ALBB-015933, BCP28286, HY-N0019, ZX-AN014640, ZX-AT022124, Tox21_201444, Tox21_303650, Tox21_500412, BBL010490, BS0244, CCG-38357, CD-190, LMPK12050038, MFCD00016954, s1849, SBB066056, STK801626, ZINC18847034, Daidzein (4',7-Dihydroxyisoflavone), 7-hydroxy-3-(4-hydroxyphenyl)-4H-, AKOS002385052, Isoflavone, 4',7-dihydroxy- (8CI), AC-6035, ACN-034764, CS-2332, Daidzein, purum, >=98.0% (TLC), KS-5260, LP00412, LS-2143, MCULE-8239511422, SDCCGMLS-0066422.P001, IDI1_001023, SMP1_000089, NCGC00015365-01, NCGC00015365-02, NCGC00015365-03, NCGC00015365-04, NCGC00015365-05, NCGC00015365-06, NCGC00015365-07, NCGC00015365-08, NCGC00015365-09, NCGC00015365-10, NCGC00015365-11, NCGC00015365-12, NCGC00015365-13, NCGC00015365-14, NCGC00015365-15, NCGC00015365-16, NCGC00015365-17, NCGC00015365-18, NCGC00025156-01, NCGC00025156-02, NCGC00025156-03, NCGC00025156-04, NCGC00025156-05, NCGC00025156-06, NCGC00025156-07, NCGC00025156-08, NCGC00025156-09, NCGC00025156-10, NCGC00168978-01, NCGC00168978-02, NCGC00257367-01, NCGC00258995-01, NCGC00261097-01, AJ-70673, AK-94232, AN-45238, CC-17424, KB-49550, SC-46504, ST057515, AB0010476, AB1004493, BB 0259520, D2668, EU-0100412, FT-0080019, FT-0603419, FT-0665448, N1862, R1341, 7-hydroxy-3-(4-hydroxyphenyl)-chromen-4-one, 7-Hydroxy-3-(4-hydroxy-phenyl)-chromen-4-one, 7-HYDROXY-3-(4-HYDROXYPHENYL)CHROMONE, C10208, D 7802, D17500, S00273, US8552057, 7, AB00052712-08, AB00052712_10, 486D668, C-15745, Daidzein, primary pharmaceutical reference standard, I06-0011, SR-01000075492-1, SR-01000075492-3, SR-01000075492-7, SR-01000075492-8, BRD-K42095107-001-02-3, BRD-K42095107-001-05-6, BRD-K42095107-001-08-0, SR-01000075492-12, 80E3ED75-D852-4D97-9BD6-B5ADE7EA25A1, 7-Hydroxy-3-(4-hydroxy-phenyl)-4H-1-benzo-pyran-4-one, UNII-71B37NR06D component ZQSIJRDFPHDXIC-UHFFFAOYSA-N, Daidzein, United States Pharmacopeia (USP) Reference Standard, Daidzein, Pharmaceutical Secondary Standard; Certified Reference Material, 4 inverted exclamation marka,7-Dihydroxyisoflavone; 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7-Hydroxy-3-(4-hydroxyphenyl)chromone

ID: 25

InChIKey: AGBQKNBQESQNJD-UHFFFAOYSA-N
SMILES: C1CSSC1CCCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 864
synonyms found at PubChem are:
dl-Thioctic acid, thioctic acid, alpha-Lipoic acid, 1077-28-7, 5-(1,2-Dithiolan-3-yl)pentanoic acid, DL-alpha-Lipoic acid, 1,2-dithiolane-3-pentanoic acid, Thioctacid, 6,8-Thioctic acid, 6-Thioctic acid, alpha Lipoic Acid, Lipothion, Biletan, dl-Lipoic acid, Liposan, Thioctsan, Tioctacid, Rac-lipoate, DL-6,8-Thioctic acid, alpha-Liponsaeure, DL-6-Thioctic acid, alpha-liponic acid, 1,2-Dithiolane-3-valeric acid, Thioktsaeure, Tioctidasi, (RS)-Lipoic acid, 6,8-Dithiooctanoic acid, espa-lipon, Thioctic acid dl-form, 62-46-4, 5-(1,2-Dithiolan-3-yl)valeric acid, Acetate-replacing factor, 6,8-Thiotic acid, Thioctansaeure, 5-(Dithiolan-3-yl)valeric acid, Protogen A, 6-Thiotic acid, 5-(dithiolan-3-yl)pentanoic acid, DL-1,2-Dithiolane 3-valeric acid, Thioktsaeure [German], Thioctsaeure, liponic acid, Thiooctic acid, Pyruvate oxidation factor, DL-Thiocticacid, DL-.alpha.-Lipoic acid, alpha-Liponsaeure [German], DL-1,2-Dithiolane-3-valeric acid, NSC 90788, Lipoic acid, alpha, NSC 628502, (+-)-1,2-Dithiolane-3-pentanoic acid, .alpha.-Liponic acid, CHEBI:16494, (+/-)-1,2-Dithiolane-3-pentanoic acid, Thioctic acid [JAN], C8H14O2S2, Tioctidasi acetate replacing factor, DL-1,2-Dithiolan-3-valeriansaeure, (.+-.)-Lipoic acid, EINECS 200-534-6, EINECS 214-071-2, (RS)-.alpha.-Lipoic acid, BRN 0081853, BRN 0122410, lipoate, 5-[3-(1,2-dithiolanyl)]pentanoic acid, CHEMBL33864, DL-1,2-Dithiolan-3-valeriansaeure [German], (.+-.)-.alpha.-Lipoic acid, AGBQKNBQESQNJD-UHFFFAOYSA-N, 1,2-DITHIOLANE-3-VALERIC ACID, (+-)-, NSC90788, Thioctic acid (JAN), NCGC00016032-06, 1,2-Dithiolane-3-pentanoic acid, (+-)-, DSSTox_CID_5508, DSSTox_RID_77816, DSSTox_GSID_25508, Berlition, Thiogamma, biomolipon, duralipon, Thioctidase, Alipure, AlphaLipogamma, Thiotacid, biomo lipon, espa lipon, Alpha Lipogamma, Alpha-Lipogamma, Pleomix Alpha, Thioctacide T, Verla Lipon, AlphaLipon Stada, .alpha.-Lipoic acid, Alpha Lippon AL, Alpha Lipon Stada, Alpha-Lipon Stada, Liponsaureratiopharm, alpha-lipon 300, SMR000058198, CAS-1077-28-7, Liponsaure-ratiopharm, (+-)-Lipoic acid, (+-)-Thioctic acid, alpha Liponsaure von ct, SR-01000737460, (RS)-alpha-Lipoic acid, (+-)-alpha-lipoic acid, alphalipoic acid, Alpha Lipoic, Alphalipoic-acid, a-lipoic acid, Thioctic acid [INN:BAN:JAN], HSDB 7818, D,L-Lipoic acid, Thiotomin (TN), D,L-Thioctic acid, lipoic acid (LA), ( )-a-Lipoic acid, LIPOIC-ACID, ()-alpha-Lipoic acid, PubChem14559, Spectrum_001618, 5-(1,2-dithiolan-3-yl)-pentanoate, Thioctic acid, dl-form, R(+)Alpha Lipoic Acid, Lip(S2), Spectrum2_001605, Spectrum3_001188, Spectrum4_000217, Spectrum5_001298, cid_864, (.+-.)-Thioctic acid, Lipoic acid, alpha [NF], ACMC-209ug2, bmse000542, D0P6PQ, Epitope ID:150922, (.+/-.)-Lipoic acid, AC1Q5W3Z, ACMC-1BU44, SCHEMBL51065, BSPBio_002835, KBioGR_000853, KBioSS_002098, 5-19-07-00237 (Beilstein Handbook Reference), MLS000069736, MLS001332379, MLS001332380, MLS002153365, DivK1c_000912, SPECTRUM1503941, (R)-(+)- a-Lipoic acid, SPBio_001609, AC1L1A75, DL-Thioctic acid, 98% 5g, DTXSID7025508, BDBM10515, CTK8G6693, HMS502N14, KBio1_000912, KBio2_002098, KBio2_004666, KBio2_007234, KBio3_002335, MolPort-002-461-878, NINDS_000912, thioctic acid (alpha-lipoic acid), HMS1922M22, HMS3649H08, Pharmakon1600-01503941, ACT14091, ALBB-030318, BCP13221, BCP14048, BCP18944, DL-6,8-DITHIOOCTANOIC ACID, HY-N0492, KS-000001JT, Tox21_110285, Tox21_201808, Tox21_303092, BBL013878, CCG-39063, dl-1,2-Dithiolane-3-pentanoic acid, LS-448, MFCD00005474, NSC-90788, NSC628502, NSC758651, SBB003484, STK801969, ()-1,2-Dithiolane-3-pentanoic acid, AKOS000121582, AKOS016339634, Tox21_110285_1, AM84329, AN-6965, CS-4370, EBD2203019, KS-1322, LS40210, MCULE-1034910084, NSC-758651, RP26250, TRA0030345, ( )-1,2-Dithiolane-3-pentanoic acid, 1,?2-?Dithiolane-?3-?pentanoic acid, IDI1_000912, NCGC00016032-02, NCGC00016032-03, NCGC00016032-04, NCGC00016032-05, NCGC00016032-07, NCGC00016032-08, NCGC00016032-09, NCGC00016032-11, NCGC00090872-01, NCGC00090872-02, NCGC00090872-03, NCGC00090872-04, NCGC00090872-05, NCGC00256970-01, NCGC00259357-01, (+/-)-alpha-Lipoic acid, >=98.0%, AC-22673, AN-41842, BR-72974, KB-50374, LS-63315, NCI60_042014, O217, SC-12524, SC-16262, SC-83283, ST073359, SBI-0051871.P002, 5-(1,2-Dithiolan-3-yl)pentanoic acid #, AB0010770, TR-001856, 1,2-Dithiolane-3-valeric acid, (.+-.)-, FT-0622068, FT-0625429, L0058, ST24032861, 1,2-Dithiolane-3-pentanoic acid, (.+-.)-, 1,2-Dithiolane-3-valeric acid, (.+/-.)-, 1,2-Dithiolane-3-pentanoic acid, (.+/-.)-, 3049-EP2316827A1, C00725, D00086, J10446, M-5249, AB00052393_09, 1,2-Dithiolane-3-pentanoic acid, (+-)- (9CI), I09-0884, J-002007, J-520421, SR-01000737460-2, SR-01000737460-6, F2191-0208, Thioctic acid, European Pharmacopoeia (EP) Reference Standard, (+/-)-alpha-Lipoic acid, BioReagent, cell culture tested, >=99%, (+/-)-alpha-Lipoic acid, synthetic, >=99% (titration), powder, Alpha Lipoic Acid, United States Pharmacopeia (USP) Reference Standard, AfAE'A centa' notA inverted exclamation markAfasA'A|AfAE'Adaggeratrade mark?-Lipoic Acid, Thioctic acid containing impurity B, European Pharmacopoeia (EP) Reference Standard, Thioctic acid for system suitability, European Pharmacopoeia (EP) Reference Standard, 27779-68-6

ID: 26

InChIKey: APIXJSLKIYYUKG-UHFFFAOYSA-N
SMILES: CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2

biological descriptors:

CFTR relevance: induced chloride efflux only in Calu-3 cells

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment Apical membrane & subapical compartment

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"Z Servetnyk" "C Andersson" "GM Roomans"

CID is 3758
synonyms found at PubChem are:
3-Isobutyl-1-methylxanthine, IBMX, 28822-58-4, isobutylmethylxanthine, 1-METHYL-3-ISOBUTYLXANTHINE, Methylisobutylxanthine, 3-Isobutyl-1-methyl-1H-purine-2,6(3H,7H)-dione, Xanthine, 3-isobutyl-1-methyl-, 3-Isobutyl-1-methyxanthine, 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-, Methyl-isobutylxanthine, 3-Isobutyl 1-methylxanthine, UNII-TBT296U68M, NSC 165960, CCRIS 4290, 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione, CHEBI:34795, 3-isobutyl-1-methyl-7H-xanthine, 3-Isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione, 3-isobutyl-1-methyl-3,9-dihydro-1H-purine-2,6-dione, 2-Acetoxy-Benzoic Acid, 3-Isobutyl-Methylxanthine, EINECS 249-259-3, NSC165960, CHEMBL275084, TBT296U68M, 1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione, APIXJSLKIYYUKG-UHFFFAOYSA-N, 3-isobutyl-1-methylxanthine (ibmx), IN1293, 3,7-Dihydro-3-isobutyl-1-methyl-1H-purine-2,6-dione, J-640140, 1-methyl-3-(2-methylpropyl)-1,3,7-trihydropurine-2,6-dione, 1H-purine-2,6-dione, 3,9-dihydro-1-methyl-3-(2-methylpropyl)-, 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, Isobutyltheophylline, IMX, SMR000326697, SR-01000075185, 3 Isobutyl 1 methylxanthine, 1zkl, 1zkn, 3ecn, 3itu, 3jwr, 2hd1, 2r8q, 3qi4, AC1L1GNB, Spectrum2_001705, Spectrum2_001735, Spectrum3_001958, Spectrum4_001052, Spectrum5_001856, Lopac-I-5879, D03ADX, D0GY2T, D0R6MT, MolMap_000030, AC1Q1PM4, Lopac0_000642, Oprea1_135287, Oprea1_228781, SCHEMBL50315, 3-isobutyl-1-methylxantliine, BSPBio_001153, BSPBio_003558, GTPL388, KBioGR_000493, KBioGR_001344, KBioGR_002566, KBioSS_000493, KBioSS_002575, 1-methyl-3-isobutyl-xanthine, MLS001056732, MLS001066424, 3-Isobutyl-1-methyl-xanthine, DivK1c_000922, SPECTRUM1505298, SPECTRUM2300204, SPBio_001690, SPBio_001810, DTXSID0040549, BCBcMAP01_000110, BDBM15336, CHEBI:43253, CTK3J1633, HMS502O04, KBio1_000922, KBio2_000493, KBio2_002566, KBio2_003061, KBio2_005134, KBio2_005629, KBio2_007702, KBio3_000905, KBio3_000906, KBio3_002878, KBio3_003044, KS-00001CXM, 3-isobutyl-1-methyl-9H-xanthine, cMAP_000087, MolPort-001-737-339, MolPort-001-792-510, NINDS_000922, Bio1_000456, Bio1_000945, Bio1_001434, Bio2_000407, Bio2_000887, HMS1362I15, HMS1792I15, HMS1990I15, HMS2090J10, HMS2231C11, HMS3262A05, HMS3369E16, HMS3403I15, HMS3604D14, HMS3648O18, ALBB-024315, ZINC3861807, Tox21_500642, 3-ISOBUTHYL-1-METHYLXANTHINE, ANW-54495, BDBM50027176, BS0316, CCG-39513, CCG-39624, GL2425, HSCI1_000261, MFCD00005584, PDSP1_000324, PDSP2_000322, SC2964, AKOS003390599, AKOS015903085, CS-3361, DB07954, LP00642, MCULE-3854999514, NSC-165960, SC 2964, VZ21530, IDI1_000922, IDI1_002162, NCGC00015559-01, NCGC00015559-02, NCGC00015559-03, NCGC00015559-04, NCGC00015559-05, NCGC00015559-06, NCGC00015559-07, NCGC00015559-08, NCGC00015559-09, NCGC00015559-10, NCGC00015559-11, NCGC00094009-01, NCGC00094009-02, NCGC00094009-03, NCGC00094009-04, NCGC00094009-05, NCGC00094009-06, NCGC00261327-01, Xanthine, 1-methyl-3-(2-methylpropyl), AJ-46242, AK-84450, BC219667, HY-12318, SC-84962, ST055758, IBMX(NSC165960; SC2964), 3-isobutyl-1-methyl-7H-purine-2,6-dione, AX8087568, DB-047466, LS-162537, [Eur J Pharmacol 170: 35 (1989)], B7206, EU-0100642, FT-0615920, R4973, WLN: T56 BM DN FNVNVJ F1Y1&1 H1, 3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione, C13708, I 5879, 3-Isobutyl-1-methylxanthine, BioUltra, >=99%, 822I584, L001156, 3-Isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione, 3-Isobutyl-1-methyl-3,9-dihydro-purine-2,6-dione, J-800144, SR-01000075185-1, SR-01000075185-6, 3-Isobutyl-1-methylxanthine, >=99% (HPLC), powder, BRD-K94979336-001-06-9, BRD-K94979336-001-09-3, I14-18716, 1H-Purine-2, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-, 1-methyl-3-(2-methylpropyl)-3,9-dihydro-1H-purine-2,6-dione, 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione

ID: 27

InChIKey: AUYYCJSJGJYCDS-LBPRGKRZSA-N
SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5920
synonyms found at PubChem are:
liothyronine, triiodothyronine, 3,3',5-Triiodo-L-thyronine, 6893-02-3, Liothyronin, Tresitope, 3,5,3'-triiodothyronine, L-Liothyronine, triothyrone, Liothyroninum, Liotironina, 3,5,3'-Triiodo-L-thyronine, L-T3, T3, Triiodo-L-thyronine, Lyothyronine, 3,3',5-Triiodothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, L-3,5,3'-Triiodothyronine, 3,5,3'TRIIODOTHYRONINE, (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid, T3 (amino acid), T3 (Hormone), L-3,3',5-TriioDOThyronine, T3 liothyronine, Liothyronine [INN:BAN], Euthroid-1, Euthroid-2, Euthroid-3, Thyrolar-1, Thyrolar-2, Thyrolar-3, Liotironina [INN-Spanish], Tri-Thyrotope, Euthroid-0.5, Thyrolar-0.5, Liothyronine (INN), T3 (VAN), Triiodothyronine, l-, Thyrolar-0.25, THYROID HORMONE, 3,5,3'-Tri-iodo-L-thyronine, CHEBI:18258, T3 (Triiodothyronine), Triiodothyronine (T3), L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, Triomet-131, T3 (LIOTRIX), Liothyroninum [INN-Latin], CHEMBL1544, UNII-06LU7C9H1V, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine, (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid, 06LU7C9H1V, 3,3',5-Triiodothyronine, L-, HSDB 3110, Triiodo-thyroninum, AUYYCJSJGJYCDS-LBPRGKRZSA-N, EINECS 229-999-3, MFCD00002593, NSC 80203, 4-(3-Iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine, BRN 2710227, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, L-triiodothyronine, L-3-(4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine, Alanine, 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-, L-, Cytomel (TN), DSSTox_CID_3216, DSSTox_RID_76928, DSSTox_GSID_23216, TRIIODOTHYRONINE (T3 OR LIOTHYRONINE, ACTIVE) (6-11%), CAS-6893-02-3, SR-05000000455, Cyronine, NSC-46046, C15H12I3NO4, 1xzx, Tertroxin (TN), 5714-08-9, Prestwick_135, PubChem20012, Spectrum_001445, Prestwick0_000853, Prestwick1_000853, Prestwick2_000853, Prestwick3_000853, Spectrum2_001984, Spectrum3_001887, Spectrum4_000326, Spectrum5_001793, T-3, Liothyroninum[INN-Latin], L-T3|||L-Liothyronine, D0D8QI, D0S6JG, Epitope ID:131324, AC1L1LF0, SCHEMBL8300, NCIStruc1_000449, Liothyronine modified release, REGID_for_CID_5920, BSPBio_000865, BSPBio_003394, KBioGR_000671, KBioGR_002568, KBioSS_001925, KBioSS_002577, 3,3'5-Triiodo-L-thyronine, MLS000028458, 3,5,3'-triodo-L-thyronine, SPBio_002167, SPBio_002786, BPBio1_000953, GTPL2634, L-3,3',5-triiodo-Thyronine, 3,3',5-Trichloro-L-thyromine, 3,3\',5-triiodo-L-thyronine, DTXSID8023216, BCBcMAP01_000192, BDBM18860, CTK1A2555, HY-A0070A, KBio2_001925, KBio2_002568, KBio2_004493, KBio2_005136, KBio2_007061, KBio2_007704, KBio3_002897, KBio3_003046, (2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid, cMAP_000088, MolPort-003-850-717, HMS1570L07, HMS2097L07, HMS2235A22, HMS3714L07, ZINC3830999, Tox21_110029, Tox21_301943, ANW-60592, CT-833, NCGC00013556, 3,5,3'-triiodo-L-thyronine (T3), Thyronine, 3,3',5-triiodo-, L-, AKOS016003266, 3,3',5-Triiodo-L-thyronine, 95%, AM83597, CCG-220853, CS-4141, DB00279, SMP1_000179, NCGC00013556-01, NCGC00013556-02, NCGC00013556-03, NCGC00013556-04, NCGC00096669-01, NCGC00096669-02, NCGC00255336-01, [125I]T3, AS-17446, KB-28438, KB-99685, LS-16137, SC-11044, SMR000058402, SBI-0206718.P001, DB-021796, Thyronine, 3,3',5-triiodo-, L-(6CI), TR-031350, Thyronine, 3,3',5-triiodo-, L- (6CI), C02465, D08128, 893T023, SR-01000003143, SR-01000003143-4, SR-05000000455-2, SR-05000000455-3, 3,5,3 inverted exclamation marka-Triiodo-L-thyronine, BRD-K89152108-001-03-3, 3,3',5-Triiodo-L-thyronine, >=95% (HPLC), powder, Z2216208625, L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-(9CI), UNII-O48UO55HR0 component AUYYCJSJGJYCDS-LBPRGKRZSA-N, L-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-Alanine, L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- (9CI), Liothyronine, United States Pharmacopeia (USP) Reference Standard, 3,3',5 Triiodothyronine (T3), IRMM(R) certified Reference Material, (2S)-2-AMINO-3-[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]PROPANOIC ACID, (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid, Liothyronine, Pharmaceutical Secondary Standard; Certified Reference Material, 3,3',5-Triiodo-L-thyronine (T3) solution, 100 mug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, 57164-27-9, 7013-53-8, (2S)-2-azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate, AC1OFCLR, CHEBI:533015, 3,3',5-triiodo-L-thyronine zwitterion, 4-(3-iodo-4-hydroxy-phenoxy)-3,5-diiodophenylalanine, (S)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]-propionic acid

ID: 28

InChIKey: AVBSIKMUAFYZAV-UHFFFAOYSA-N
SMILES: C1=C2C(=CC(=C1Cl)Cl)NC(=O)C(=O)N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1845
synonyms found at PubChem are:
25983-13-5, 6,7-Dichloroquinoxaline-2,3(1H,4H)-dione, DCQX, 6,7-DICHLORO-1,4-DIHYDRO-2,3-QUINOXALINEDIONE, 6,7-dichloroquinoxaline-2,3-diol, 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione, 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione, 2,3-Dihydroxy-6,7-dichloroquinoxaline, CHEMBL284028, 2,3-Quinoxalinedione,6,7-dichloro-1,4-dihydro-, Spectrum_001661, ACMC-209gnv, SpecPlus_000650, Lopac-D-133, AC1L1CDC, Spectrum2_000537, Spectrum3_001668, Spectrum4_000630, Spectrum5_001426, Biomol-NT_000181, D0S6TW, AC1Q3Q7M, Lopac0_000418, Benzil-related compound, 58, BSPBio_003455, KBioGR_001220, KBioSS_002141, DivK1c_006746, SCHEMBL463608, SPECTRUM1504232, SPBio_000553, BPBio1_001174, SCHEMBL8122389, BDBM22778, CTK4F6896, KBio1_001690, KBio2_002141, KBio2_004709, KBio2_007277, KBio3_002675, KS-00001AMJ, DTXSID70274337, AVBSIKMUAFYZAV-UHFFFAOYSA-N, CHEBI:113553, MolPort-001-758-250, ZX-AT029321, 6,7-Dichloro-2,3-quinoxalinedione, ANW-25865, CCG-39598, MFCD00078575, AKOS015850366, AKOS022421095, ZINC100004920, 6,7-dichloro-2,3-dihydroxyquinoxaline, FCH1322390, NCGC00015311-01, NCGC00015311-02, NCGC00015311-03, NCGC00015311-04, NCGC00015311-05, NCGC00093842-01, NCGC00093842-02, NCGC00093842-03, NCGC00095336-01, NCGC00095336-02, AJ-70442, DB-014624, CS-0038531, D-133, EU-0100418, FT-0609662, V4741, 6,7-dichloro-quinoxaline-2,3(1H,4H)-dione, I08-631, SR-01000075444, 2,3-Quinoxalinedione, 6,7-dichloro-1,4-dihydro-, J-016207, SR-01000075444-1, BRD-K80576679-001-03-1, 6,7-dichloro-1,2,3,4-tetrahydroquinoxaline-2,3-dione, 6,7-Dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline

ID: 29

InChIKey: CEUMONXVSJOJIH-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC(=CC3=NC=C2)Cl.Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"N Liu" "D Rotin" "HR de Jonge" "BJ Scholte" "JW Hanrahan" "M Wilke" "R Robert" "GW Carlile" "J Liao" "P Lesimple" "H Balghi" "B Kus" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3085326
synonyms found at PubChem are:
Glafenine hydrochloride, 65513-72-6, Glafenine (hydrochloride), DSSTox_CID_25497, DSSTox_RID_80916, DSSTox_GSID_45497, SR-01000473478, C19H17ClN2O4.ClH, 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate, Prestwick_628, Glafenin hydrochloride, Glafenine(hydrochloride), AC1MJ4AX, NCGC00016909-01, CAS-65513-72-6, MLS002154254, SCHEMBL970807, CHEMBL1572751, DTXSID7045497, CTK8G0041, HY-B1153A, KS-00001FBC, MolPort-004-964-888, HMS1568L08, Tox21_110678, 2430AH, AKOS024374941, Tox21_110678_1, CCG-220293, CS-6517, MCULE-3160845237, Benzoic acid, 2-((7-chloro-4-quinolinyl)amino)-, 2,3-dihydroxypropyl ester, monohydrochloride, NCGC00094881-07, SMR001233515, Glafenine hydrochloride, analytical standard, ST51015012, SR-01000473478-1, SR-01000473478-3, 2,3-dihydroxypropyl 2-(7-chloroquinolin-4-ylamino)benzoate hydrochloride, 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate, chloride, 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate hydrochloride, AKOS026749774

ID: 30

InChIKey: DCFXOTRONMKUJB-QMDUSEKHSA-N
SMILES: CCCN1CCO[C@H]2[C@H]1COC3=C2C=C(C=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957668
synonyms found at PubChem are:
300576-59-4, (+)-PD 128907 hydrochloride, (+/-)-PD 128,907 hydrochloride, 112960-16-4, S(+)-PD 128,907 hydrochloride, PD 125,530, (+)-PD 128,907 hydrochloride, rel-(4aR,10bR)-4-Propyl-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol hydrochloride, (+)-(4aR,10bR)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride, (4aR,10bR)-4-Propyl-3,4,4a,10b-tetrahydro-2H,5H-chromeno[4,3-b][1,4]oxazin-9-ol hydrochloride, PD128907 HCl, MFCD00210210, PD128907 Hydrochloride, SR-01000075396, (4aR,10bR)-rel-4-Propyl-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol hydrochloride, EU-0101038, MLS002153393, CHEMBL1256778, SCHEMBL15937756, MolPort-003-959-173, (y)-PD 128,907 hydrochloride, (?)-PD 128,907 hydrochloride, Tox21_501038, R(-)-PD 128,908 hydrochloride, (+/-)-PD 128907 hydrochloride, AKOS015900216, API0008818, DS-8408, EX-3305, LP00988, LP01038, SPD-128907, NCGC00094286-01, NCGC00094286-02, NCGC00261723-01, AK164058, SMR001230774, AX8300668, KB-277078, LS-191187, EU-0100988, P-183, P-216, ST24034753, (+)PD 128907, S(+)-(4aR,10bR)-3,4,4a,10b-, (+)-PD 128,907 hydrochloride, >97%, solid, A820165, SR-01000597915, J-002884, J-017752, R(-)-PD 128,908 hydrochloride, >97%, solid, SR-01000075396-1, SR-01000075396-2, SR-01000597915-1, ( inverted question mark)-PD 128,907 hydrochloride, I14-10033, ( inverted exclamation markA)-PD 128,907 hydrochloride, (+/-)-PD 128,907 hydrochloride, solid, >=98% (HPLC), Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride, (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride, (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-[1]benzopyrano[4,3-b][1,4]oxazin-9-ol hydrochloride, (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol hydrochloride, R( C)-(4aS,10bS)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol, trans-( inverted exclamation markA)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride, trans-(+/-)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride

ID: 31

InChIKey: DEFVIWRASFVYLL-UHFFFAOYSA-N
SMILES: C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

biological descriptors:

CFTR relevance: Fe3+ chelator

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"G Wang"

CID is 6207
synonyms found at PubChem are:
EGTA, 67-42-5, Egtazic acid, Ethylenebis(oxyethylenenitrilo)tetraacetic acid, Gedta, Ebonta, 6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-, 1,2-Bis[2-[bis(carboxymethyl)amino]ethoxy]ethane, Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid, Ethylene Glycol Tetraacetic Acid, H4egta, Egtazic acid [USAN:INN], Ethylene glycol bis(2-aminoethyl ether)tetraacetic acid, NSC 615010, [Ethylenebis(oxyethylenenitrilo)]tetraacetic acid, Acide egtazique [INN-French], Acido egtazico [INN-Spanish], Acidum egtazicum [INN-Latin], Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, Glycoletherdiaminetetraacetic Acid, 1,2-Bis(2-dicarboxymethylaminoethoxy)ethane, Glycol-etherdiaminetetraacetic acid, UNII-526U7A2651, Ethylenedioxybis(ethyleneamino)tetraacetic acid, C14H24N2O10, EINECS 200-651-2, (Ethylenebis(oxyethylenenitrilo))tetraacetic acid, 3,12-bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecanedioic acid, BRN 1717370, CHEBI:30740, Glycoletherdiamine-N,N,N',N'-tetraacetic Acid, DEFVIWRASFVYLL-UHFFFAOYSA-N, Glycoletherdiamine-tetraacetic acid, ethylene glycol bis(2-aminoethyl)tetraacetic acid, Ethylene glycol bis(aminoethyl ether)tetraacetate, Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, Ethylenebis(oxyethylenenitrilo)tetra(acetic acid), Glycol ether diamine tetraacetic acid, NSC615010, NCGC00015416-02, ACETIC ACID, (ETHYLENEBIS(OXYETHYLENENITRILO))TETRA-, Ethylene glycol, di(2-(N,N-dicarboxylmethyl)amino)ethyl ether, Ethylene glycol bis(beta-aminoethyl ether)-N,N'-tetraacetic acid, Ethyleneglycol-bis(beta-aminoethyl ether)-N,N1-tetra-acetic acid, 526U7A2651, 2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid, DSSTox_CID_25151, DSSTox_RID_80705, DSSTox_GSID_45151, [ethylenebis-(oxyethylenenitrilo)]-tetraacetic acid, W-104715, Acide egtazique, Acido egtazico, Acidum egtazicum, ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid, Ethyleneglycol-bis(beta-aminoethyl)-N,N,N′,N′-tetraacetic Acid, Magnesium-EGTA, Tetrasodium EGTA, 2,2',2'',2'''-[ethane-1,2-diylbis(oxyethane-2,1-diylnitrilo)]tetraacetic acid, CAS-67-42-5, EGATA, 31571-71-8, Egtazic Acid Disodium Salt, ethylene glycol bis[2-aminoethyl ether]tetraacetic acid, titriplex(r) vi, idranal(tm) vi, idranal(r) vi, 2-[2-[2-[2-(Bis(carboxymethyl)amino)ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid, 2-{[2-(2-{2-[bis(carboxymethyl)amino]ethoxy}ethoxy)ethyl](carboxymethyl)amino} acetic acid, ETHYLENE GLYCOL-bis-(beta-AMINO-ETHYLETHER)-N,N,N',N'-TETRAACETIC ACID, OAEuEa, Chel™-DE, EDGA, EGTA; Egtazic acid, Egtazic acid (USAN), AC1Q5WJB, Lopac-E-4378, Ethylenebis(oxyethylenenitrile)tetraacetic Acid, bmse001011, D0O5VI, AC1L1M0X, Lopac0_000512, SCHEMBL22901, KSC353A5B, MLS000069445, CHEMBL240390, DTXSID2045151, CTK2F3050, MolPort-001-794-631, HMS3261H05, ZINC3861663, Tox21_110141, Tox21_500512, ANW-43739, GE7249, MFCD00004291, SBB053599, 31571-71-8 (hydrochloride salt), AKOS004910388, Tox21_110141_1, API0002646, CCG-204603, LP00512, MCULE-9762822541, NSC-615010, RTR-031285, NCGC00015416-01, NCGC00015416-03, NCGC00015416-04, NCGC00015416-05, NCGC00093909-01, NCGC00093909-02, NCGC00261197-01, AJ-73376, AK-50026, AN-23760, CC-27442, LS-12095, SC-74749, SMR000059072, U228, AX8127175, KB-254014, TR-031285, B7195, E0106, E0805, EU-0100512, FT-0606293, ST24030705, ST50308400, D03967, E 4378, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, ethylenebis(oxyethylenenitrilo) tetraacetic acid, [ethylenebis-(oxyethylenenitrilo)]tetraacetic acid, C-21321, Ethyleneglycol-bis(aminoethylether)-tetraacetic ac, SR-01000075861, ethyleneglycol-bis(aminoethyl ether)-tetraacetic acid, ethyleneglycol-bis-(aminoethylether)-tetraacetic acid, I06-0315, SR-01000075861-1, 1,2-di(2-aminoethoxy)ethane-nnn'n'-tetra-acetic acid, 1,2-di(2-aminoethoxy)ethane-n,n,n',n'-tetraacetic acid, Ethylene glycol bis-(2-aminoethyl ether)tetraacetic acid, ethylenedioxybis(ethylamine)-n,n,n',n'-tetraacetic acid, Ethyleneglycol bis-(2-aminoethyl)ether tetraacetic acid, 1,2-Bis(2-aminoethoxyethane)-N,N,N',N'-tetraacetic acid, 3,6-Dioxaoctane-1,8-diamine-N,N,N',N'-tetraacetic acid, 2,2'-Ethylenedioxybis(ethylamine)-N,N,N',N'-tetraacetic acid, ethylene glycol bis(b-aminoethyl ether)-n,n'-tetracetic acid, ethyleneglycol-bis(beta-aminoethyl)-n,n,n',n'-tetraacetic acid, OO paragraph signthorn (1/4)E<< degrees +/-OO>>uANEAOOEa, Acetic acid, [ethylenebis(oxyethylenenitrilo)]tetra- (6CI,8CI), ethylene glycol bis (2-aminoethylether)-n,n,n',n'-tetraacetic acid, ethylene glycol bis(2-aminoethylether)-n,n,n',n'-tetraacetic acid, Ethylene glycol bis(b-aminoethyl ether)-N,N,N',N'-tetraacetic acid, ethylene glycol bis(beta-aminoethylether)-n,n,n',n'-tetraacetic acid, 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid, 6,9-Dioxa-3,12-diazatetradecanedioicacid, 3,12-bis(carboxymethyl)-, Ethylene glycol bis(.beta.-aminoethyl ether)-N,N,N',N'-tetraacetic acid, ethylene glycol-bis(.beta.-aminoethyl ether)-n,n,n',n'-tetraacetic acid, Ethylene glycol-bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA), ethylene glycol-bis(beta-aminoethyl ether)-n,n,n',n'-tetraacetic acid, ethylene glycol-bis-(beta-amino-ethyl ether)-n,n,n',n'-tetraacetic acid, ethylene glycol-bis-(beta-amino-ethyl ether)-n,n,n',n-tetraacetic acid, 2,11-bis(carboxymethyl)-5,8-dioxa-2,11-diazadodecane-1,12-dicarboxylic acid, 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid #, 6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)- (9CI), Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, >=97.0%, Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, >=98.0% (T), Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, BioXtra, >=97 .0%, Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid (EGTA), Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 97% 10g, OO paragraph signthorn (1/4) paragraph signthornOOAN paragraph signthorn degrees .EAOOEa, 33382-61-5, 56618-01-0, Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, BioUltra, for molecular biology, >=99.0% (T), Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid, for molecular biology, >=97.0%

ID: 32

InChIKey: DHKIZPIDZINAAO-UHFFFAOYSA-N
SMILES: CCOC1=CC=CC=C1NC2=NC(=CS2)C3=C(N=C(S3)NC(=O)C4=CC=CC=C4)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

"Y Wang" "MC Bartlett" "DM Clarke" "TW Loo"

CID is 1144666
synonyms found at PubChem are:
MLS000561135, Oprea1_004830, Oprea1_493857, SCHEMBL837737, CHEMBL1451149, MolPort-001-986-136, ZINC888726, AKOS000562160, MCULE-3678609376, BAS 02936934, SMR000156160, ST075397, EU-0078236, SR-01000492602, SR-01000492602-1, N-[2-(2-Ethoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide, N-(5-{2-[(2-ethoxyphenyl)amino](1,3-thiazol-4-yl)}-4-methyl(1,3-thiazol-2-yl)) benzamide

ID: 33

InChIKey: DUEPRVBVGDRKAG-UHFFFAOYSA-N
SMILES: CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C

biological descriptors:

CFTR relevance: medium CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2566
synonyms found at PubChem are:
carbofuran, Furadan, 1563-66-2, Curaterr, Yaltox, Chinufur, Crisfuran, Furacarb, Furadan 3G, Furadan G, Furadan 4f, Carbofurane, Pillarfuran, Kenofuran, Niagara 10242, Karbofuranu, Brifur, BAY 70143, Niagara nia-10242, Bayer 70143, FMC 10242, NIA 10242, Carbodan, Furodan, Karbofuranu [Polish], Me f248, Caswell No. 160A, Carbofuran [ANSI:BSI:ISO], 2,2-Dimethyl-7-coumaranyl N-methylcarbamate, ENT 27,164, 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate, OMS 864, 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate, BAY 78537, CCRIS 4017, Furadane, D 1221, CHEBI:34611, 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate, HSDB 1530, OMS-864, C2292-59A, EINECS 216-353-0, UNII-SKF77S6Y67, NIA-10242, 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate, 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate, EPA Pesticide Chemical Code 090601, NSC 167822, BRN 1428746, Furadan 75 WP, AI3-27164, Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, Spectrum_001895, SpecPlus_000516, 2,2-Dimethyl-2,2-dihydrobenzofuranyl-7 N-methylcarbamate, Spectrum2_001871, Spectrum3_000848, Spectrum4_000688, Spectrum5_002012, 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate, Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester, Oprea1_828936, BSPBio_002435, KBioGR_001155, KBioSS_002425, SPECTRUM330057, DivK1c_006612, 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, SPBio_001742, SKF77S6Y67, C12H15NO3, KBio1_001556, KBio2_002419, KBio2_004987, KBio2_007555, KBio3_001935, DUEPRVBVGDRKAG-UHFFFAOYSA-N, 5-17-04-00048 (Beilstein Handbook Reference), N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7 [Polish], LS-900, NSC167822, (2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate, NCGC00094541-01, NCGC00094541-02, WLN: T56 BOT&J C1 C1 IOVM1, 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate, 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate), DSSTox_CID_249, C14291, CARBOFURAN (PESTICIDE/FERTILIZER MIXTURE), DSSTox_RID_75463, DSSTox_GSID_20249, Q-200797, 2,2-Dimethyl-2,3-dihydrobenzoduranyl-7-N-methylcarbamate, 7-Benzofurano, 2,3-dihydro-2,2-dimethyl, methylcarbamate, Diafuran, Sunfuran, Terafuran, Brifer, Furadan F, CAS-1563-66-2, Curater, Tripart nex, Carbofuran mixture, Carbofuran, 98%, Niagaral 242, Sipcam UK carbosip 5G, AC1L1DYQ, SCHEMBL21656, BIDD:ER0379, Carbofuran, analytical standard, 426008_ALDRICH, 45370_RIEDEL, CHEMBL416081, DTXSID9020249, CTK8F8460, ZINC56963, N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7, Tox21_201955, Tox21_300623, BDBM50064619, CCG-39409, ZINC00056963, AKOS015907855, Carbofuran 100 microg/mL in Methanol, NA 2757, NSC-167822, Carbofuran 10 microg/mL in Cyclohexane, NCGC00094541-03, NCGC00094541-04, NCGC00094541-05, NCGC00254481-01, NCGC00259504-01, AC-10588, AN-49451, CC-25405, O719, ZB001897, SBI-0052542.P002, 2,2-dimethyl-7-benzofuranyl methylcarbamate, 2,2-dihydrobenzofuranyl-7 N-methylcarbamate, 2,2-dimethylbenzofuranyl-7-N-methylcarbamate, FT-0602922, Carbofuran, PESTANAL(R), analytical standard, 563C662, A809741, C-12281, I14-2658, (2,2-dimethyl-3H-benzofuran-7-yl) N-methylcarbamate, 2,2-DIMETHYL-7-BENZOFURANOL, METHYLCARBAMATE, BRD-K53570330-001-01-2, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl methylcarbamate, 7-Benzofuranol,3-dihydro-2,2-dimethyl-, methylcarbamate, 2, 3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, 2, 3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-benzofurane-7-yl methyl-carbamate, 2,3-dihydro-2,2-dimethylbenzofuran-7-yl N-methyl-carbamate, 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate #, 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-methylcarbamate, 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate, 9CI, Carbamic acid, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester, Carbamic acid, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester, N-methylcarbamic acid (2,2-dimethyl-3H-benzofuran-7-yl) ester, 2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANOL, METHYLCARBAMATE, Benzofuran-7-ol, 2,3-dihydro, 2,2-dimethyl, N-methylcarbamate, Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester, Carbofuran;2,2-Dimethyl-2,2-dihydrobenzofuranyl-7-N-methylcarbamate; 2,2-Dimethyl-2,3-dihydrobenzofuranyl 7-methylcarbamate; 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate;, InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14

ID: 34

InChIKey: FFINMCNLQNTKLU-UHFFFAOYSA-N
SMILES: C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3739
synonyms found at PubChem are:
IODIPAMIDE, Adipiodone, Iodipamic acid, 606-17-7, Biligrafin, Bilignostum, Cholografin, Cholospect, Transbilix, Adipiodon, Bilignost, Adipiodona, Adipiodonum, Adipiodonum [INN-Latin], Adipiodona [INN-Spanish], Iodipamide [USAN], UNII-TKQ858A3VW, Iodipamide (USP), 3,3'-[(1,6-DIOXOHEXANE-1,6-DIYL)DIIMINO]BIS(2,4,6-TRIIODOBENZOIC ACID), 3,3'-(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid), Adipiodone (JAN/INN), Adipiodone meglumine, EINECS 210-105-5, Cholografin Meglumine, BRN 2230896, TKQ858A3VW, N,N''-Adipoyl-bis(3-amino-2,4,6-triiodbenzoesaeure), IDB, IODIPAMIDE MEGLUMINE, NCGC00016523-03, CAS-606-17-7, DSSTox_CID_3153, Radio-cholografin, Benzoic acid, 3,3'-((1,6-dioxo-1,6-hexanediyl)diimino)bis(2,4,6-triiodo-, Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo-, 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid, DSSTox_RID_76893, DSSTox_GSID_23153, 3,3-Adipoyldiiminobis(2,4,6-Triiodobenzoic Acid), 3,3'-Adipoyldiiminobis(2,4,6-triiodobenzoic Acid), 3,3'(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid), Benzoic acid, 3,3'-(adipoyldiimino)bis(2,4,6-triiodo-, 3-[5-[(3-CARBOXY-2,4,6-TRIIODO-PHENYL)CARBAMOYL]PENTANOYLAMINO]-2,4,6-TRIIODO-BENZOIC ACID, Iodipamide [USP:INN], HSDB 8066, C20H14I6N2O6, meglumine adipiodone, 3-{5-[N-(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanoylamino}-2,4,6-triiodo benzoic acid, Adipiodone [INN], AC1L1GLQ, Prestwick0_000939, Prestwick1_000939, Prestwick2_000939, Prestwick3_000939, D07OIX, AC1Q5M0A, SCHEMBL37678, BSPBio_000878, 4-14-00-01122 (Beilstein Handbook Reference), MLS001066414, SPBio_003047, BPBio1_000966, GTPL7400, CHEMBL1165268, DTXSID6023153, CHEBI:31176, CTK5B1937, FFINMCNLQNTKLU-UHFFFAOYSA-N, MolPort-001-783-518, HMS1570L20, HMS2097L20, HMS2232C09, HMS3370I13, HMS3714L20, Tox21_113504, SBB058156, AKOS015964892, Tox21_113504_1, API0001390, CCG-220939, DB04711, MCULE-6605409948, VA10176, NCGC00016523-01, NCGC00016523-02, NCGC00016523-05, CC-23800, LS-35555, SMR000471884, AB00513970, FT-0627253, I0299, ST51015022, X6858, D01774, C-23613, Iodipamide, analytical standard, for drug analysis, SR-01000760542, SR-01000760542-2, BRD-K67261995-001-03-4, I14-92724, Iodipamide, United States Pharmacopeia (USP) Reference Standard, Benzoic acid,3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo-, 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid, 3-[[6-[(3-carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid

ID: 35

InChIKey: FTVWIRXFELQLPI-UHFFFAOYSA-N
SMILES: C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 932
synonyms found at PubChem are:
naringenin, 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, 67604-48-2, 4',5,7-Trihydroxyflavanone, Naringenine, (+/-)-Naringenin, 480-41-1, naringetol, salipurpol, (-)-Naringenin, NARIGENIN, Salipurol, 93602-28-9, 5,7,4'-Trihydroxyflavanone, (S)-Naringenin, NSC 34875, ( inverted exclamation markA)-Naringenin, CHEMBL32571, MLS000028739, MLS000738094, CHEBI:50202, Flavanone, 4',5,7-trihydroxy-, FTVWIRXFELQLPI-UHFFFAOYSA-N, NSC11855, NSC34875, SMR000059039, 4',7-Trihydroxyflavanone, NSC 11855, Flavanone,5,7-trihydroxy-, Q-100521, EINECS 207-550-2, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one, pelargidanon 1602, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-, naringenin-7-sulfate, NSC-34875, Narngenn, rac Naringenin, CCRIS 8135, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, NSC-11855, 4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-, Naringenin (NAR), Prestwick_531, EINECS 266-769-1, Naringenin, 90%, (R,S)-Naringenin, BE 14348A, BE-14348A, Opera_ID_106, AC1L1ACN, AC1Q6KJD, Prestwick0_000466, Prestwick1_000466, Prestwick2_000466, Prestwick3_000466, Oprea1_194140, SCHEMBL20571, 4 ,5,7-Trihydroxyflavanone, BSPBio_000572, MLS001146907, SPBio_002511, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, BPBio1_000630, MEGxp0_000358, SCHEMBL1934259, ACon1_000582, BDBM19461, CTK7J9188, DTXSID50274239, MolPort-000-861-091, (+/-)-Naringenin, >=95%, HMS1569M14, HMS2096M14, HMS2231O18, HMS3352B08, HMS3373N07, HMS3656G15, Naringenin, natural (US), 98%, KS-000001ZW, ZX-AT026530, ANW-43843, BN0800, CN0031, SBB006461, Naringenin solution, 20 mM in DMSO, (+/-)-5,7,4'-Trihydroxyflavanone, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, AKOS015895052, (+/-)-Naringenin, analytical standard, CS-W012357, KS-5142, LS-5089, MCULE-5489217450, RL05877, (+/-)-Naringenin, ~95% (HPCE), KS-00000R53, SMP1_000060, NCGC00017346-02, NCGC00017346-03, NCGC00017346-04, NCGC00095963-01, NCGC00095963-02, NCGC00095963-03, 4CN-0924, AC-20273, AK122638, AN-45184, K702, LS-39547, SC-18078, ST057236, AB1003941, AB1009825, AX8246816, KB-187979, KB-196356, ST2418556, TR-017609, TR-037462, 4CH-012369, FT-0082287, FT-0630981, N0072, M-7677, Naringenin, disposable screening library format, S00279, 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-one, I06-0445, I06-0536, J-523457, 4',5,7-Trihydroxyflavanone solution, 20 mM in DMSO, BRD-A94669766-001-02-6, BRD-A94669766-001-04-2, 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one, EC19096C-4404-4A16-9BF9-92F9F358E005, ( )-Naringenin; 4?,5,7-Trihydroxyflavanone; H-1-benzopyran-4-one, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, (S)- #, ( inverted exclamation markA)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4 inverted exclamation marka,5,7-Trihydroxyflavanone

ID: 36

InChIKey: HEFNNWSXXWATRW-UHFFFAOYSA-N
SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3672
synonyms found at PubChem are:
ibuprofen, 15687-27-1, 2-(4-Isobutylphenyl)propanoic acid, Motrin, Brufen, Advil, Nurofen, Dolgit, Liptan, Nuprin, Anflagen, Buburone, Butylenin, Ibumetin, Ibuprocin, Medipren, Ebufac, Lamidon, Mynosedin, Apsifen, Epobron, Haltran, Roidenin, Trendar, Adran, Andran, Bluton, Nobfen, Nobgen, PediaProfen, Rufen, Nobfelon, Brufort, Inabrin, Pantrop, Rebugen, Suspren, Tabalon, (RS)-Ibuprofen, Anco, Urem, 2-[4-(2-methylpropyl)phenyl]propanoic acid, Ibu-slo, Brufanic, Ibuprohm, Napacetin, Ibufen, Ibren, 4-Isobutylhydratropic acid, p-Isobutylhydratropic acid, Novoprofen, Proartinal, Amersol, Dibufen, Dolocyl, Ibuprin, Lidifen, Optifen, Ostofen, Panafen, Paxofen, Proflex, Quadrax, Uprofen, Burana, Carol, Dolgin, Midol, Profen, Rafen, Cobo, Ifen, (+-)-Ibuprofen, Cap-Profen, Tab-Profen, Artril 300, Ibu-Tab, Midol 200, duralbuprofen, Butacortelone, Amibufen, Antalfene, Antarene, Antiflam, Balkaprofen, Betaprofen, Bukrefen, Buracaps, Citalgan, Combiflam, Daiprophen, Dentigoa, Dignoflex, Dolgirid, Dolmaral, Dolofort, Dolormin, Doltibil, Dysdolen, Esprenit, Exneural, Femapirin, Fibraflex, Gelufene, Ibucasen, Ibudolor, Ibuflamar, Ibugesic, Ibuhexal, Ibulagic, Ibumerck, Ibupirac, Ibuprofeno, Jenaprofen, Kratalgin, Lebrufen, Librofem, Malafene, Manypren, Mensoton, Neobrufen, Novogent, Nuprilan, Oralfene, Relcofen, Rhinadvil, Seclodin, Sednafen, Seklodin, Seskafen, Solpaflex, Suprafen, Syntofene, Alaxan, Algofen, Amelior, Anafen, Antagil, Artofen, Artril, Brofen, Bruflam, Bufeno, Bufigen, Bupron, Dansida, Dolibu, Dolofen, Dolofin, Dologel, Dolomax, Doloren, Dolven, Dorival, Duafen, Duobrus, Easifon, Emflam, Eputex, Faspic, Femadon, Femafen, Femidol, Fenbid, Fendol, Fenspan, Grefen, Gynofug, Ibubest, Ibubeta, Ibudol, Ibufug, Ibugel, Ibugen, Ibular, Ibulav, Ibuleve, Ibulgan, Ibumed, Ibusal, Ibutid, Inflam, Inoven, Isodol, Junifen, Lopane, Melfen, Moment, Narfen, Nerofen, Noalgil, Nobafon, Noritis, Norton, Novadol, Opturem, Ostarin, Ozonol, Paduden, Perofen, Provon, Ranofen, Sadefen, Salivia, Siyafen, Solufen, Stelar, Sugafen, Tatanal, Tempil, Unipron, Bloom, Cesra, Cunil, Dalsy, Ergix, Gofen, Ipren, Irfen, Kesan, Rofen, Rufin, Rupan, Tofen, Tonal, Upfen, Zafen, Zofen, alpha-(4-Isobutylphenyl)propionic acid, Drin, Ibol, Pediatric Advil, Apo-Ibuprofen, Brufen Retard, 4-Isobutyl-alpha-methylphenylacetic acid, Ibu-Attritin, Neo-Helvagit, (+/-)-Ibuprofen, Deep Relief, Dolo-Dolgit, Ibu-slow, Novo-Profen, Neo-Mindol, Dolofen-F, Donjust B, Nagifen-D, Children's Advil, Dura-Ibu, Motrin IB, Togal N, Children's Motrin, IP-82, Ibu-Tab 200, Children's Ibuprofen, Dularbuprofen, Ibuprofenum, Caldolor, Ibuprofene, Ibuprophen, Salprofen, Tabalon 400, (+-)-p-Isobutylhydratropic acid, Brufen 400, Emflam-200, Junior Strength Advil, Kontagripp Mono, DOLO PUREN, Junior Strength Motrin, Novo Dioxadol, Schmerz-Dolgit, Act-3, Ak+C2278tren, ACHES-N-PAIN, Hemagene Tailleur, Hydratropic acid, p-isobutyl-, Advil Liqui-Gels, (4-Isobutylphenyl)-alpha-methylacetic acid, Adex 200, Junior Strength Ibuprofen, Advil, Children's, Am-Fam 400, Codral Period Pain, Children's Elixsure, p-Isobutyl-2-phenylpropionic acid, (+-)-Ibuprophen, (+-)-2-(p-Isobutylphenyl)propionic acid, 58560-75-1, 2-(4-ISOBUTYLPHENYL)PROPIONIC ACID, Actiprofen, alpha-(p-isobutylphenyl)propionic acid, Midol IB Cramp Relief, Genpril, Codral, VUFB 9649, Bayer Select Pain Relief, Pedia-Profen, Ibuprofene [INN-French], Ibuprofenum [INN-Latin], Novogent N, RD 13621, Apsifen-F, Racemic ibuprofen, Ibuprofeno [INN-Spanish], U-18,573, alpha-p-Isobutylphenylpropionic acid, MOTRIN MIGRAINE PAIN, IB-100, Motrin IB Gelcaps, UCB 79171, (+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid, 2-(4-Isobutyl-phenyl)-propionic acid, Motrin (TN), CCRIS 3223, CHEBI:5855, Advil (TN), alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid, CHILDREN'S ADVIL-FLAVORED, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, HSDB 3099, Children's Elixsure IB, Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)-, 2-(p-Isobutylphenyl)propionic acid, EINECS 239-784-6, CHEMBL521, U 18573, NSC 256857, BRN 2049713, MLS000069733, Ibu, (S)-4-Isobutyl-alpha-methylphenylacetic acid, R.D. 13621, HEFNNWSXXWATRW-UHFFFAOYSA-N, (R)-Ibuprofen, (+/-)-p-Isobutylhydratropic acid, Acide (isobutyl-4-phenyl)-2 propionique [French], C13H18O2, U-18573, NSC256857, .alpha.-(p-isobutylphenyl)propionic acid, NCGC00015529-09, .alpha.-(4-Isobutylphenyl)propionic acid, Acide (isobutyl-4 phenyl)-2 propionique, SMR000058184, 4-Isobutyl-.alpha.-methylphenylacetic acid, alpha-Methyl-4-(isobutyl)phenylacetic acid, DSSTox_CID_732, (+/-)-2-(4-Isobutylphenyl)Propanoic Acid, [(+/-)-2-(4-Isobutylphenyl)-propionic Acid, I 4883, DSSTox_RID_75759, DSSTox_GSID_20732, alpha-Methyl-4-[2-methylpropyl] benzeneacetic Acid, .alpha.-Methyl-4-(2-methylpropyl)benzeneacetic acid, Alivium, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl), (+-)-, Pedea, Advil migraine, Ibuprofen-Zinc, Perrigo ibuprofen, Trauma-Dolgit Gel, CAS-15687-27-1, SR-01000000214, Ibuprofen I.V. Solution, Advil Migraine Liqui-Gels, Ibupril, Ibuprox, Aktren, Ibup, Ibux, Fenbid Spansule, IP82, CDT-ibuprofen, Nurofen Meltlets, (y)-Ibuprofen, Ratiodolor (TN), Arthrofen (TN), Calprofen (TN), Espidifen (TN), Finalflex (TN), Galprofen (TN), Ibuprofen,(S), Ibuprosyn (TN), IP 82, Kratalgin (TN), Midol Liquid Gels, Neobrufen (TN), Norvectan (TN), Salvarina (TN), Solpaflex (TN), (+) ibuprofen, Algoflex (TN), Caldolor (TN), Dismenol (TN), Dolofort (TN), Dolormin (TN), EmuProfen (TN), Ibumetin (TN), Ibuprofen (Advil), Nureflex (TN), Spedifen (TN), Spidifen (TN), (?)-Ibuprofen, Alivium (TN), Bonifen (TN), Bugesic (TN), Diverin (TN), Doloraz (TN), Dorival (TN), Fenpaed (TN), Ibalgin (TN), Ibuleve (TN), Ibuprom (TN), Medicol (TN), Nurofen (TN), Orbifen (TN), Panafen (TN), Perifar (TN), Rimafen (TN), Alaxan (TN), Brufen (TN), Burana (TN), Dolgit (TN), Ebufac (TN), Fenbid (TN), Herron Blue (TN), Ibu-Vivimed (TN), Ibugel (TN), Ibumax (TN), Ibuxin (TN), Moment (TN), Narfen (TN), Neofen (TN), Nuprin (TN), Profin (TN), Retard (TN), I-profen (TN), ibuprofen lysine salt, Aktre (TN), Dalsy (TN), Hedex (TN), Ibuprofen (Dolgesic), Ipren (TN), p-Isobutylhydratropate, Upfen (TN), Dolo-Spedifen (TN), Ibuprofen [USAN:USP:INN:BAN:JAN], Combunox (Salt/Mix), (A+/-)-Ibuprofen, Ibum (TN), Ibux (TN), IBU-Ratiopharm (TN), IbuHEXAL (TN), PubChem16054, Spectrum_000849, Acide (isobutyl-4-phenyl)-2 propionique, Speedpain NANO (TN), Opera_ID_554, Eve (TN), AC1L1GGE, Spectrum2_000129, Spectrum3_000465, Spectrum4_000015, Spectrum5_000862, IBUFEN (TN), WLN: QVY&R DIY, CBMicro_005634, IBUPROFEN USP GRADE, ACMC-209df0, ACMC-209ks2, D03SHR, D0R1QE, Epitope ID:139973, p-isobutyl-hydratropic acid, EC 239-784-6, Act-3 (TN), Cambridge id 5152402, SCHEMBL3001, Isobutylpropanoicphenolic acid, Lopac0_000691, Para-Isobutylhydratropic Acid, BSPBio_002170, Ibuprofen - Adooq Bioscience, KBioGR_000389, KBioSS_001329, KSC492A1B, MLS001146965, p-Isobutyl-2-phenylpropionate, ARONIS23835, BIDD:GT0050, DivK1c_000887, SPECTRUM1500347, Ibuprofen, >=98% (GC), SPBio_000178, Ibuprofen (JP17/USP/INN), AC1Q1P84, AC1Q1P85, alpha-p-Isobutylphenylpropionate, GTPL2713, Motrin IB Gelcaps (Salt/Mix), 2-p-isobutylphenylpropionic acid, DTXSID5020732, CTK3J2010, HEFNNWSXXWATRW-UHFFFAOYSA-, HMS502M09, KBio1_000887, KBio2_001329, KBio2_003897, KBio2_006465, KBio3_001390, Advil Cold & Sinus (Salt/Mix), Ibuprofen [USAN:BAN:INN:JAN], Ibuprofen 1.0 mg/ml in Methanol, MolPort-001-791-802, NINDS_000887, Sine-Aid IB Caplets (Salt/Mix), 2-(4-Isobutylphenyl)propanoicAcid, alpha-(4-Isobutylphenyl)propionate, HMS1920F15, HMS2089P05, HMS2091N03, HMS2230N04, HMS3259G05, HMS3262K03, HMS3372M09, HMS3649M11, HMS3651A15, Pharmakon1600-01500347, ACT03248, ALBB-025647, BCP10423, BCP20325, BCP25225, KS-00000CJ0, KS-000047NV, ZAG-1701, ( inverted question mark)-Ibuprofen, (.+-.)-p-Isobutylhydratropic acid, 79261-49-7 (potassium salt), Children's Elixsure IB (Salt/Mix), Tox21_110170, Tox21_201384, Tox21_302829, Tox21_500691, 2-(4'-isobutylphenyl)propionic acid, 2-(4-isobutylphenyl) propanoic acid, 2-(4-isobutylphenyl) propionic acid, 2-(4-isobutylphenyl)-propionic acid, ANW-21658, BBL010660, BDBM50009859, CCG-38947, MFCD00010393, NSC757073, s1638, SBB064160, STK177358, (.+/-.)-p-Isobutylhydratropic acid, 2-(4-isobutylphenyl)-propionoic acid, 2-(4'-isobutylphenyl)-propionic acid, 31121-93-4 (hydrochloride salt), AKOS003237488, AKOS016340658, Propanoic acid, 2-(4-isobutylphenyl), Tox21_110170_1, CS-1931, DB01050, KS-5029, LP00691, LS-7454, MCULE-9475454445, NC00458, NSC-256857, NSC-757073, RP26239, RTR-006580, ST-1482, TRA0047278, ( inverted exclamation markA)-Ibuprofen, alpha-(4-isobutylphenyl)-propionic acid, alpha-(p-isobutylphenyl)-propionic acid, IDI1_000887, NCGC00015529-04, NCGC00015529-05, NCGC00015529-06, NCGC00015529-07, NCGC00015529-08, NCGC00015529-10, NCGC00015529-12, NCGC00015529-13, NCGC00015529-14, NCGC00015529-15, NCGC00015529-18, NCGC00089819-02, NCGC00089819-03, NCGC00089819-04, NCGC00089819-05, NCGC00089819-06, NCGC00089819-07, NCGC00256416-01, NCGC00258935-01, NCGC00261376-01, AC-11312, AN-18584, BR-47272, CPD000058184, HY-78131, NCI60_002065, SAM002264619, SC-18867, ST024750, Ibuprofen, Vetec(TM) reagent grade, 97%, SBI-0050669.P004, (+/-)-2-(p-isobutylphenyl)propionic acid, .alpha.-2-(p-Isobutylphenyl)propionic acid, AB1009266, Ibuprofen, meets USP testing specifications, KB-222912, TL8001184, TR-006580, (.+-.)-2-(p-Isobutylphenyl)propionic acid, 4-Isobutylphenyl)-.alpha.-methylacetic acid, AM20060782, BB 0258487, EU-0100691, FT-0601629, FT-0655194, I0415, ST24032335, (.+/-.)-2-(p-Isobutylphenyl)propionic acid, Ibuprofen, VETRANAL(TM), analytical standard, (r/s)-alpha-methyl-4-isobutylphenylacetic acid, C01588, D00126, J10135, M-4957, AB00052020-16, AB00052020-17, AB00052020_18, AB00052020_19, (RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid, 687I271, A831926, I01-7039, J-009349, SR-01000000214-2, SR-01000000214-4, BRD-A17655518-001-02-0, BRD-A17655518-001-12-9, SR-01000000214-13, Ibuprofen, British Pharmacopoeia (BP) Reference Standard, Z1695709473, (+/-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid, Ibuprofen, European Pharmacopoeia (EP) Reference Standard, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl), (+/-)-, Ibuprofen, United States Pharmacopeia (USP) Reference Standard, (? inverted exclamation markA)-2-(4-Isobutylphenyl)Propanoic Acid, Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl), (.+/-.)-, Ibuprofen, Pharmaceutical Secondary Standard; Certified Reference Material, Ibuprofen for peak identification, European Pharmacopoeia (EP) Reference Standard, N4,N4' -Di(naphthalen-1-yl)-N4,N4' -bis(4-vinylphenyl)biphenyl-4,4'-diamine, (2s)-2-[4-(2-methylpropyl)phenyl]propionic acid DEXIBUPROFEN (S)-(+)-2-(4-ISOBUTYLPHENYL)PROPIONIC ACID (S)-(+)-4-ISOBUTYL-ALPHA-ME, 139466-08-3, 2-(4-Isobutylphenyl)-propionic acid ; alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid ; p-Isobutylhydratropic acid, InChI=1/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

ID: 37

InChIKey: HJORMJIFDVBMOB-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3

biological descriptors:

CFTR relevance: Phosphodiesterase 4 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"KL Hamilton" "PC Chao"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5092
synonyms found at PubChem are:
rolipram, 61413-54-5, ZK 62711, Rolipramum, Rolipramum [Latin], 4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone, Adeo, (+/-)-Rolipram, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, Rolipram [USAN:INN], [3H]rolipram, 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one, (R,S)-rolipram, [3H]-rolipram, ZK-62711, CHEMBL63, EINECS 262-771-1, BRN 1588548, MLS000069691, CHEBI:104872, HJORMJIFDVBMOB-UHFFFAOYSA-N, 4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone, IN1123, 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one, ME-3167, 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, SB 95952, SMR000058510, DSSTox_CID_24124, DSSTox_RID_80104, DSSTox_GSID_44124, 4-[3-(cyclopentoxy)-4-methoxy-phenyl]pyrrolidin-2-one, 2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, (4R)-4-[3-(Cyclopentyloxy)-4 Methoxyphenyl)pyrrolidin-2-one, CPD000058510, SR-01000000162, (plusmn)-rolipram, NCGC00016899-01, CAS-61413-54-5, AC1L1JLC, Opera_ID_1749, Prestwick0_000924, Prestwick1_000924, Prestwick2_000924, Prestwick3_000924, D05HPY, D0T5PO, UPCMLD-DP110, AC1Q6O0R, Lopac0_001072, SCHEMBL27930, BSPBio_000828, BSPBio_001356, KBioGR_000076, KBioSS_000076, Rolipram (JAN/USAN/INN), MLS000758273, MLS000759531, MLS001146912, MLS001424084, MLS006010272, SPBio_003007, BPBio1_000912, GTPL5260, GTPL5313, Pyrrolidone, 4-(3-cyclopentyloxy-4-methoxyphenyl)-2-, DTXSID3044124, UPCMLD-DP110:001, UPCMLD-DP110:002, BDBM14361, CTK5F4996, KBio2_000076, KBio2_002644, KBio2_005212, KBio3_000151, KBio3_000152, AOB5326, MolPort-000-860-686, Bio2_000076, Bio2_000556, HMS1361D18, HMS1570J10, HMS1791D18, HMS1989D18, HMS2051N15, HMS2090J16, HMS2097J10, HMS2232F06, HMS3263G06, HMS3267A05, HMS3369J08, HMS3393N15, HMS3402D18, HMS3654P06, HMS3655J21, HMS3714J10, Pharmakon1600-01505683, BCP21910, BCP23388, KS-000004QI, ZX-AN014777, Tox21_110672, Tox21_501072, 2028AH, 2691AH, BS0164, MFCD00270906, NSC760125, Rolipram, solid, >=98% (HPLC), s1430, AKOS015959793, Tox21_110672_1, CCG-100965, CCG-205149, CS-1754, DB01954, INB0003603, KS-1400, LP01072, NC00215, NSC-760125, IDI1_033826, NCGC00015898-03, NCGC00015898-04, NCGC00015898-05, NCGC00015898-06, NCGC00015898-07, NCGC00015898-08, NCGC00015898-09, NCGC00015898-11, NCGC00015898-12, NCGC00015898-15, NCGC00089796-02, NCGC00089796-04, NCGC00089796-05, NCGC00089796-06, NCGC00089796-07, NCGC00089796-08, NCGC00261757-01, AK174013, AN-39288, BC660173, HY-16900, KB-86388, SAM001246766, SAM001246998, SC-47452, ZK-62771, SBI-0051042.P002, AB0109850, LS-138709, ZK 62 711, AB00513966, EU-0101072, FT-0738515, R0110, ST50405218, D01783, R 6520, AB00384360-17, AB00384360_19, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone, SR-01000000162-3, SR-01000000162-4, SR-01000000162-5, SR-01000000162-9, 4-[3-Cyclopentyloxy-4-methoxyphenyl]-2-pyrrolidinone, BRD-A34255068-001-04-8, BRD-A34255068-001-26-1, SR-01000000162-12, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinon, 4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one, 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrolidin-2-one, 4-(3-cyclopentyloxy-4-methoxyphenyl)-pyrrolidin-2-one, 4-[4-Methoxy-3-(cyclopentyloxy)phenyl]-2-pyrrolidinone, 2-Pyrrolidinone,4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]- (9CI), ZK 62711, SB 95952, ME-3167, Adeo, 61413-54-5

ID: 38

InChIKey: HKQYGTCOTHHOMP-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 5280378
synonyms found at PubChem are:
formononetin, 485-72-3, Biochanin B, Formononetol, 7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one, 7-Hydroxy-4'-methoxyisoflavone, 4'-O-methyldaidzein, 7-hydroxy-3-(4-methoxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)-, UNII-295DQC67BJ, 7-Hydroxy-3-(4-methoxyphenyl)-4-benzopyrone, CHEBI:18088, Isoflavone, 7-hydroxy-4'-methoxy-, EINECS 207-623-9, NSC 93360, NSC-93360, 7-Hydroxy-3-(4-methoxyphenyl)chromone, 295DQC67BJ, HKQYGTCOTHHOMP-UHFFFAOYSA-N, NSC93360, IN1330, 7-hydroxy-3-(4-methoxyphenyl)-4H-benzopyran-4-one, Q-100540, 7-Hydroxy-3-(4′-methoxyphenyl)-4H-benzopyran-4-one, SMR000470932, SR-01000765510, formononetine, 7-hydroxy-4'-methoxy-isoflavone, Formononetin,(S), PubChem9850, AC1NQWYT, Spectrum_000373, SpecPlus_000223, Daidzein 4-methyl ether, Spectrum2_000560, Spectrum3_000660, Spectrum4_001429, Spectrum5_000258, DSSTox_CID_2311, D0M7BR, Formononetin (Formononetol), DSSTox_RID_76544, NCIOpen2_005983, DSSTox_GSID_22311, Oprea1_139748, Oprea1_815287, SCHEMBL62915, BSPBio_002299, KBioGR_001878, KBioSS_000853, SPECTRUM102007, MLS000697593, MLS006011897, BIDD:ER0119, DivK1c_006319, SPBio_000639, CHEMBL242341, DTXSID4022311, CTK8C4788, Formononetin, analytical standard, KBio1_001263, KBio2_000853, KBio2_003421, KBio2_005989, KBio3_001519, KS-00000HZV, MolPort-000-450-946, HMS1922N18, HMS2231I04, HMS3369C07, HMS3655N22, ALBB-030789, Formononetin, >=99.0% (TLC), HY-N0183, TNP00176, Tox21_301848, ANW-73131, BBL010458, BDBM50021398, CCG-38727, CF0045, LMPK12050037, MFCD00016948, s2299, SBB016445, STK801612, ZINC18847036, AKOS000270811, AC-8001, AN-8422, CS-3081, MCULE-4171151967, SDCCGMLS-0066428.P001, 7-hydroxy-4'-methoxy-Isoflavone (8CI), NCGC00017269-01, NCGC00017269-02, NCGC00017269-03, NCGC00017269-04, NCGC00017269-05, NCGC00017269-06, NCGC00095207-01, NCGC00095207-02, NCGC00095207-03, NCGC00178715-01, NCGC00255167-01, 4CN-0880, AJ-70674, AK106172, AS-11642, BC216233, CAS-485-72-3, CC-28828, LS-39701, NCI60_042081, SC-04770, ST024713, AB0010475, AX8016260, Isoflavone, 7-hydroxy-4'-methoxy- (8CI), Neochanin; Flavosil;NEOCHANIN;Formononetol, F0868, FT-0626540, FT-0632204, K-080, N1625, 3-(4-methoxyphenyl)-7-oxidanyl-chromen-4-one, C00858, AB00052676-07, 485F723, A827555, AE-641/01968055, C-16842, 7-hydroxy-3-(4-methoxyphenyl)-1-benzopyran-4-one, I06-0241, SR-01000765510-3, SR-01000765510-4, BRD-K55567017-001-02-4, BRD-K55567017-001-06-5, F3139-1207, 7-hydroxy-3-(4-methoxyphenyl)-4H-benzopyran-4-one(9CI), 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)- (9CI), Formononetin, United States Pharmacopeia (USP) Reference Standard, 7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 7-Hydroxy-3-(4-methoxyphenyl)chromone, 7-Hydroxy-4'-methoxyisoflavone

ID: 39

InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N
SMILES: CS(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Narlawar" "KL Kirk" "K Bernard" "B Schmidt" "W Wang"

"MJ Caplan" "K Du" "J Glöckner-Pagel" "S Canny" "D Rubin" "V Rajendran" "M Pearson" "SA Weiner" "ME Egan" "GL Lukacs"

CID is 679
synonyms found at PubChem are:
dimethyl sulfoxide, DMSO, Methyl sulfoxide, 67-68-5, Methylsulfinylmethane, Dimethylsulfoxide, Dimethyl sulphoxide, Methane, sulfinylbis-, Demsodrox, Demasorb, Demavet, Dimexide, Domoso, Dromisol, Durasorb, Infiltrina, Somipront, Syntexan, Deltan, Demeso, Dolicur, Hyadur, sulfinylbismethane, Dimethyl sulfur oxide, Dermasorb, Dipirartril-tropico, Doligur, Kemsol, Topsym, Gamasol 90, Sclerosol, Sulfinylbis(methane), Rimso-50, Dimethylsulfoxid, Dimethylsulfoxyde, Rimso 50, Dimethylsulphoxide, Caswell No. 381, SQ 9453, Dimetil sulfoxido, Sulfinylbis-methane, Dimethyli sulfoxidum, Topsym (rescinded), Rimso-5, NSC-763, methanesulfinylmethane, Domoso (Veterinary), CCRIS 943, (methylsulfinyl)methane, methylsulfoxide, (CH3)2SO, Dimexidum, DMS-90, sulfinyldimethane, NSC 763, Dimetilsolfossido [DCIT], A 10846, Dimethyl sulpoxide, M 176, UNII-YOW8V9698H, HSDB 80, Methane, 1,1'-sulfinylbis-, EPA Pesticide Chemical Code 000177, DMS 70, DMS 90, DMS-70, Dimethylsulfoxyde [INN-French], AI3-26477, Dimetil sulfoxido [INN-Spanish], Dimethyli sulfoxidum [INN-Latin], Methyl Sulfoxide: DMSO, EINECS 200-664-3, CHEMBL504, S(O)Me2, NSC763, YOW8V9698H, CHEBI:28262, IAZDPXIOMUYVGZ-UHFFFAOYSA-N, SQ-9453, DIMETHYL SULFOXIDE- D6, Rimso, Dimethylsulphinyl, Dimetilsolfossido, Sulfoxide, dimethyl, Rimso 100, Diluent, dimethysulfoxide, Decap, dimethlysulfoxide, dimethvlsulfoxide, dimethyisulfoxide, dimethylsulphoxid, dimethy sulfoxide, dimetyl sulfoxide, dimethyisulphoxide, Dimethyl sulfoxide [USAN:INN], Methyl sulphoxide, dimethyl sulfoxyde, dimethyl-sulfoxide, dimethyl-sulfoxyde, Diemthyl sulfoxide, dimethyl suiphoxide, dimethyl-sulphoxide, dirnethyl sulfoxide, Dimethyl sulfoxixde, methylsulfmylmethane, Dimethyl Sulfoxydum, dimethyl sulf oxide, qCbPPAD]h@, Dimethyl sulfoxide BP, 2-Thiapropane2-oxide, (methanesulfinyl)methane, Dimethyl sulfoxide [USAN:USP:INN:BAN], DMSO, sterile filtered, DMSO; Methyl sulfoxide, AC1Q4GSG, Methyl sulfoxide (8CI), Rimso-50 (TN), DMSO, Dimethyl Sulfoxide, DSSTox_CID_1735, (DMSO), C2H6OS, D08HVE, EC 200-664-3, Sulfinylbis-methane (9CI), AC1L19RZ, ACMC-1BH88, DSSTox_RID_76298, H3C-SO-CH3, BIDD:PXR0182, DSSTox_GSID_21735, Dimethyl sulfoxide, >=99%, Dimethyl sulfoxide, for HPLC, KSC353A9L, DMSO, 80% aqueous solution, Methane, sulfinylbis- (9CI), Dimethyl sulfoxide (USP/INN), DIMETHYL SULFOXIDE, ACS, WLN: OS1&1, Dimethyl sulfoxide, >=99.5%, Dimethyl sulfoxide, PCR Reagent, DTXSID2021735, CTK2F3095, Dimethyl sulfoxide, ACS reagent, Methyl sulfoxide, >=99%, FG, Dimethyl sulfoxide, p.a., 99%, MolPort-002-317-295, Dimethyl sulfoxide, 99% 500g, Dimethyl sulfoxide, LR, >=99%, Pharmakon1600-01506122, KS-00000VT9, ZINC5224188, Tox21_300957, ANW-42740, BDBM50026472, MFCD00002089, NSC760436, STL264194, Dimethyl sulfoxide, AR, >=99.5%, AKOS000121107, CCG-213615, DB01093, Dimethyl sulfoxide, analytical standard, LS-1568, MCULE-2005841258, NSC-760436, RL04586, RP18373, RTR-022725, CAS-67-68-5, MRF-0000764, (methanesulfinyl)methanedimethyl sulfoxide, Dimethyl sulfoxide, for molecular biology, NCGC00163958-01, NCGC00163958-02, NCGC00163958-03, NCGC00254859-01, AN-20755, AN-23766, Dimethyl sulfoxide, anhydrous, >=99.9%, Dimethyl sulfoxide, HPLC grade, 99.9%, SC-16101, Dimethyl Sulfoxide [for Spectrophotometry], Dimethyl sulfoxide, for HPLC, >=99.5%, Dimethyl sulfoxide, for HPLC, >=99.7%, AB1004054, AB1004058, TL8004767, TR-022725, D0798, D5293, Dimethyl sulfoxide, ACS reagent, >=99.9%, Dimethyl sulfoxide, AldraSORB(TM), 99.8%, FT-0625099, InChI=1/C2H6OS/c1-4(2)3/h1-2H, 1926-EP1441224A2, 1926-EP2269977A2, 1926-EP2269978A2, 1926-EP2269979A1, 1926-EP2269985A2, 1926-EP2269989A1, 1926-EP2269990A1, 1926-EP2269991A2, 1926-EP2269992A1, 1926-EP2269993A1, 1926-EP2269994A1, 1926-EP2269996A1, 1926-EP2270003A1, 1926-EP2270004A1, 1926-EP2270006A1, 1926-EP2270008A1, 1926-EP2270010A1, 1926-EP2270011A1, 1926-EP2270012A1, 1926-EP2270013A1, 1926-EP2270014A1, 1926-EP2270015A1, 1926-EP2270018A1, 1926-EP2272509A1, 1926-EP2272510A1, 1926-EP2272517A1, 1926-EP2272813A2, 1926-EP2272817A1, 1926-EP2272822A1, 1926-EP2272825A2, 1926-EP2272827A1, 1926-EP2272834A1, 1926-EP2272835A1, 1926-EP2272839A1, 1926-EP2272840A1, 1926-EP2272841A1, 1926-EP2272842A1, 1926-EP2272844A1, 1926-EP2272848A1, 1926-EP2272972A1, 1926-EP2272973A1, 1926-EP2274983A1, 1926-EP2275102A1, 1926-EP2275403A1, 1926-EP2275409A1, 1926-EP2275412A1, 1926-EP2275413A1, 1926-EP2275414A1, 1926-EP2275416A1, 1926-EP2275420A1, 1926-EP2275421A1, 1926-EP2275422A1, 1926-EP2275425A1, 1926-EP2277848A1, 1926-EP2277858A1, 1926-EP2277866A1, 1926-EP2277872A1, 1926-EP2277875A2, 1926-EP2277876A1, 1926-EP2277878A1, 1926-EP2277881A1, 1926-EP2277898A2, 1926-EP2277945A1, 1926-EP2279741A2, 1926-EP2279750A1, 1926-EP2280001A1, 1926-EP2280006A1, 1926-EP2280008A2, 1926-EP2280009A1, 1926-EP2280011A1, 1926-EP2280012A2, 1926-EP2280013A1, 1926-EP2280014A2, 1926-EP2281559A1, 1926-EP2281563A1, 1926-EP2281810A1, 1926-EP2281813A1, 1926-EP2281815A1, 1926-EP2281817A1, 1926-EP2281819A1, 1926-EP2281823A2, 1926-EP2281899A2, 1926-EP2284150A2, 1926-EP2284151A2, 1926-EP2284152A2, 1926-EP2284153A2, 1926-EP2284154A1, 1926-EP2284155A2, 1926-EP2284156A2, 1926-EP2284157A1, 1926-EP2284159A1, 1926-EP2284160A1, 1926-EP2284164A2, 1926-EP2284166A1, 1926-EP2284167A2, 1926-EP2284168A2, 1926-EP2284172A1, 1926-EP2284174A1, 1926-EP2284178A2, 1926-EP2284179A2, 1926-EP2286811A1, 1926-EP2286915A2, 1926-EP2287140A2, 1926-EP2287148A2, 1926-EP2287150A2, 1926-EP2287153A1, 1926-EP2287156A1, 1926-EP2287163A1, 1926-EP2287164A1, 1926-EP2287165A2, 1926-EP2287166A2, 1926-EP2287168A2, 1926-EP2289871A1, 1926-EP2289876A1, 1926-EP2289882A1, 1926-EP2289883A1, 1926-EP2289885A1, 1926-EP2289886A1, 1926-EP2289890A1, 1926-EP2289891A2, 1926-EP2289892A1, 1926-EP2289893A1, 1926-EP2289894A2, 1926-EP2292088A1, 1926-EP2292227A2, 1926-EP2292228A1, 1926-EP2292233A2, 1926-EP2292234A1, 1926-EP2292576A2, 1926-EP2292589A1, 1926-EP2292590A2, 1926-EP2292592A1, 1926-EP2292593A2, 1926-EP2292595A1, 1926-EP2292597A1, 1926-EP2292606A1, 1926-EP2292609A1, 1926-EP2292611A1, 1926-EP2292613A1, 1926-EP2292614A1, 1926-EP2292615A1, 1926-EP2292617A1, 1926-EP2292619A1, 1926-EP2292620A2, 1926-EP2292630A1, 1926-EP2295053A1, 1926-EP2295055A2, 1926-EP2295401A2, 1926-EP2295402A2, 1926-EP2295406A1, 1926-EP2295407A1, 1926-EP2295408A1, 1926-EP2295410A1, 1926-EP2295411A1, 1926-EP2295412A1, 1926-EP2295413A1, 1926-EP2295414A1, 1926-EP2295415A1, 1926-EP2295416A2, 1926-EP2295417A1, 1926-EP2295418A1, 1926-EP2295419A2, 1926-EP2295422A2, 1926-EP2295423A1, 1926-EP2295424A1, 1926-EP2295425A1, 1926-EP2295426A1, 1926-EP2295427A1, 1926-EP2295429A1, 1926-EP2295432A1, 1926-EP2295433A2, 1926-EP2295434A2, 1926-EP2295439A1, 1926-EP2295503A1, 1926-EP2295550A2, 1926-EP2298305A1, 1926-EP2298312A1, 1926-EP2298731A1, 1926-EP2298732A1, 1926-EP2298734A2, 1926-EP2298735A1, 1926-EP2298736A1, 1926-EP2298742A1, 1926-EP2298743A1, 1926-EP2298744A2, 1926-EP2298745A1, 1926-EP2298746A1, 1926-EP2298747A1, 1926-EP2298748A2, 1926-EP2298750A1, 1926-EP2298761A1, 1926-EP2298764A1, 1926-EP2298765A1, 1926-EP2298767A1, 1926-EP2298768A1, 1926-EP2298769A1, 1926-EP2298770A1, 1926-EP2298773A1, 1926-EP2298774A1, 1926-EP2298776A1, 1926-EP2298778A1, 1926-EP2298779A1, 1926-EP2298780A1, 1926-EP2298783A1, 1926-EP2301534A1, 1926-EP2301536A1, 1926-EP2301538A1, 1926-EP2301627A1, 1926-EP2301909A1, 1926-EP2301912A2, 1926-EP2301913A1, 1926-EP2301914A1, 1926-EP2301916A2, 1926-EP2301922A1, 1926-EP2301923A1, 1926-EP2301925A1, 1926-EP2301926A1, 1926-EP2301928A1, 1926-EP2301929A1, 1926-EP2301930A1, 1926-EP2301932A1, 1926-EP2301933A1, 1926-EP2301935A1, 1926-EP2301936A1, 1926-EP2301937A1, 1926-EP2301939A1, 1926-EP2301940A1, 1926-EP2302382A2, 1926-EP2302383A2, 1926-EP2305250A1, 1926-EP2305254A1, 1926-EP2305629A1, 1926-EP2305637A2, 1926-EP2305640A2, 1926-EP2305641A1, 1926-EP2305642A2, 1926-EP2305643A1, 1926-EP2305647A1, 1926-EP2305648A1, 1926-EP2305651A1, 1926-EP2305652A2, 1926-EP2305655A2, 1926-EP2305658A1, 1926-EP2305659A1, 1926-EP2305660A1, 1926-EP2305663A1, 1926-EP2305666A1, 1926-EP2305667A2, 1926-EP2305668A1, 1926-EP2305671A1, 1926-EP2305672A1, 1926-EP2305674A1, 1926-EP2305677A1, 1926-EP2305679A1, 1926-EP2305681A1, 1926-EP2305682A1, 1926-EP2305684A1, 1926-EP2305687A1, 1926-EP2305688A1, 1926-EP2305689A1, 1926-EP2305695A2, 1926-EP2305696A2, 1926-EP2305697A2, 1926-EP2305698A2, 1926-EP2305769A2, 1926-EP2305808A1, 1926-EP2308510A1, 1926-EP2308562A2, 1926-EP2308812A2, 1926-EP2308832A1, 1926-EP2308833A2, 1926-EP2308838A1, 1926-EP2308840A1, 1926-EP2308841A2, 1926-EP2308844A2, 1926-EP2308845A2, 1926-EP2308846A2, 1926-EP2308847A1, 1926-EP2308848A1, 1926-EP2308852A1, 1926-EP2308854A1, 1926-EP2308855A1, 1926-EP2308857A1, 1926-EP2308861A1, 1926-EP2308863A1, 1926-EP2308866A1, 1926-EP2308867A2, 1926-EP2308868A1, 1926-EP2308869A1, 1926-EP2308870A2, 1926-EP2308871A1, 1926-EP2308872A1, 1926-EP2308873A1, 1926-EP2308874A1, 1926-EP2308875A1, 1926-EP2308877A1, 1926-EP2308878A2, 1926-EP2308879A1, 1926-EP2308880A1, 1926-EP2308960A1, 1926-EP2311451A1, 1926-EP2311453A1, 1926-EP2311455A1, 1926-EP2311494A1, 1926-EP2311796A1, 1926-EP2311797A1, 1926-EP2311798A1, 1926-EP2311799A1, 1926-EP2311801A1, 1926-EP2311806A2, 1926-EP2311807A1, 1926-EP2311809A1, 1926-EP2311811A1, 1926-EP2311815A1, 1926-EP2311818A1, 1926-EP2311823A1, 1926-EP2311824A1, 1926-EP2311825A1, 1926-EP2311827A1, 1926-EP2311829A1, 1926-EP2311830A1, 1926-EP2311831A1, 1926-EP2311837A1, 1926-EP2311838A1, 1926-EP2311840A1, 1926-EP2311842A2, 1926-EP2311850A1, 1926-EP2314295A1, 1926-EP2314574A1, 1926-EP2314576A1, 1926-EP2314580A1, 1926-EP2314583A1, 1926-EP2314584A1, 1926-EP2314585A1, 1926-EP2314586A1, 1926-EP2314587A1, 1926-EP2314588A1, 1926-EP2314590A1, 1926-EP2314593A1, 1926-EP2315303A1, 1926-EP2316450A1, 1926-EP2316452A1, 1926-EP2316459A1, 1926-EP2316824A1, 1926-EP2316827A1, 1926-EP2316828A1, 1926-EP2316829A1, 1926-EP2316831A1, 1926-EP2316832A1, 1926-EP2316833A1, 1926-EP2316834A1, 1926-EP2316835A1, 1926-EP2316836A1, 1926-EP2316905A1, 1926-EP2316906A2, 1926-EP2371797A1, 1926-EP2371798A1, 1926-EP2371800A1, 1926-EP2371804A1, 1926-EP2371805A1, 1926-EP2371809A1, 1926-EP2371810A1, 1926-EP2371811A2, 1926-EP2374454A1, 1926-EP2374790A1, 1926-EP2374791A1, 1926-EP2374895A1, 1926-EP2377849A2, 1926-EP2380873A1, 1926-EP2380874A2, 4606-EP2269975A2, 4606-EP2269977A2, 4606-EP2269993A1, 4606-EP2269996A1, 4606-EP2269997A2, 4606-EP2270000A1, 4606-EP2270006A1, 4606-EP2270009A1, 4606-EP2270011A1, 4606-EP2270012A1, 4606-EP2270013A1, 4606-EP2270014A1, 4606-EP2270113A1, 4606-EP2270114A1, 4606-EP2272509A1, 4606-EP2272813A2, 4606-EP2272827A1, 4606-EP2272835A1, 4606-EP2272843A1, 4606-EP2272844A1, 4606-EP2272848A1, 4606-EP2272935A1, 4606-EP2275395A2, 4606-EP2275409A1, 4606-EP2275412A1, 4606-EP2275415A2, 4606-EP2275425A1, 4606-EP2275427A1, 4606-EP2277858A1, 4606-EP2277866A1, 4606-EP2277876A1, 4606-EP2277880A1, 4606-EP2277881A1, 4606-EP2280001A1, 4606-EP2280008A2, 4606-EP2280009A1, 4606-EP2280013A1, 4606-EP2280014A2, 4606-EP2281563A1, 4606-EP2281812A1, 4606-EP2281813A1, 4606-EP2281817A1, 4606-EP2281818A1, 4606-EP2284154A1, 4606-EP2284160A1, 4606-EP2284169A1, 4606-EP2286811A1, 4606-EP2287141A1, 4606-EP2287147A2, 4606-EP2287153A1, 4606-EP2287161A1, 4606-EP2287162A1, 4606-EP2287168A2, 4606-EP2289509A2, 4606-EP2289879A1, 4606-EP2289883A1, 4606-EP2289885A1, 4606-EP2289887A2, 4606-EP2289888A2, 4606-EP2289890A1, 4606-EP2289891A2, 4606-EP2289893A1, 4606-EP2289897A1, 4606-EP2292088A1, 4606-EP2292228A1, 4606-EP2292233A2, 4606-EP2292589A1, 4606-EP2292592A1, 4606-EP2292593A2, 4606-EP2292596A2, 4606-EP2292606A1, 4606-EP2292610A1, 4606-EP2292612A2, 4606-EP2292614A1, 4606-EP2292619A1, 4606-EP2292630A1, 4606-EP2295053A1, 4606-EP2295401A2, 4606-EP2295409A1, 4606-EP2295415A1, 4606-EP2295417A1, 4606-EP2295418A1, 4606-EP2295434A2, 4606-EP2295439A1, 4606-EP2298312A1, 4606-EP2298734A2, 4606-EP2298738A1, 4606-EP2298747A1, 4606-EP2298750A1, 4606-EP2298761A1, 4606-EP2298767A1, 4606-EP2298768A1, 4606-EP2298772A1, 4606-EP2301922A1, 4606-EP2301933A1, 4606-EP2301934A1, 4606-EP2305629A1, 4606-EP2305633A1, 4606-EP2305641A1, 4606-EP2305647A1, 4606-EP2305648A1, 4606-EP2305651A1, 4606-EP2305658A1, 4606-EP2305667A2, 4606-EP2305668A1, 4606-EP2305679A1, 4606-EP2305681A1, 4606-EP2305684A1, 4606-EP2305687A1, 4606-EP2305808A1, 4606-EP2308471A1, 4606-EP2308562A2, 4606-EP2308812A2, 4606-EP2308833A2, 4606-EP2308839A1, 4606-EP2308848A1, 4606-EP2308854A1, 4606-EP2308855A1, 4606-EP2308857A1, 4606-EP2308861A1, 4606-EP2308869A1, 4606-EP2308873A1, 4606-EP2308875A1, 4606-EP2309564A1, 4606-EP2309584A1, 4606-EP2311804A2, 4606-EP2311806A2, 4606-EP2311808A1, 4606-EP2311811A1, 4606-EP2311820A1, 4606-EP2311821A1, 4606-EP2311824A1, 4606-EP2311825A1, 4606-EP2311827A1, 4606-EP2311829A1, 4606-EP2311830A1, 4606-EP2311831A1, 4606-EP2311838A1, 4606-EP2311842A2, 4606-EP2314295A1, 4606-EP2314574A1, 4606-EP2314575A1, 4606-EP2314576A1, 4606-EP2314583A1, 4606-EP2314584A1, 4606-EP2314585A1, 4606-EP2314586A1, 4606-EP2315303A1, 4606-EP2315502A1, 4606-EP2316452A1, 4606-EP2316459A1, 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6129-EP2280010A2, 6129-EP2280014A2, 6129-EP2281810A1, 6129-EP2281821A1, 6129-EP2281899A2, 6129-EP2284159A1, 6129-EP2284165A1, 6129-EP2284174A1, 6129-EP2287155A1, 6129-EP2287156A1, 6129-EP2287160A1, 6129-EP2287165A2, 6129-EP2287166A2, 6129-EP2287168A2, 6129-EP2287940A1, 6129-EP2289876A1, 6129-EP2289887A2, 6129-EP2289888A2, 6129-EP2289890A1, 6129-EP2289894A2, 6129-EP2289965A1, 6129-EP2292228A1, 6129-EP2292589A1, 6129-EP2292595A1, 6129-EP2292596A2, 6129-EP2292597A1, 6129-EP2292611A1, 6129-EP2292619A1, 6129-EP2292620A2, 6129-EP2292624A1, 6129-EP2292630A1, 6129-EP2295055A2, 6129-EP2295402A2, 6129-EP2295406A1, 6129-EP2295410A1, 6129-EP2295414A1, 6129-EP2295416A2, 6129-EP2295425A1, 6129-EP2298731A1, 6129-EP2298735A1, 6129-EP2298743A1, 6129-EP2298747A1, 6129-EP2298748A2, 6129-EP2298755A1, 6129-EP2298760A1, 6129-EP2298763A1, 6129-EP2298764A1, 6129-EP2298765A1, 6129-EP2298766A1, 6129-EP2298768A1, 6129-EP2298770A1, 6129-EP2298772A1, 6129-EP2298774A1, 6129-EP2298778A1, 6129-EP2298828A1, 6129-EP2299509A1, 6129-EP2299510A1, 6129-EP2301911A1, 6129-EP2301922A1, 6129-EP2301924A1, 6129-EP2301925A1, 6129-EP2301926A1, 6129-EP2301933A1, 6129-EP2301936A1, 6129-EP2301939A1, 6129-EP2301983A1, 6129-EP2305243A1, 6129-EP2305625A1, 6129-EP2305629A1, 6129-EP2305633A1, 6129-EP2305640A2, 6129-EP2305642A2, 6129-EP2305651A1, 6129-EP2305652A2, 6129-EP2305658A1, 6129-EP2305667A2, 6129-EP2305672A1, 6129-EP2305673A1, 6129-EP2305676A1, 6129-EP2305679A1, 6129-EP2305682A1, 6129-EP2305685A1, 6129-EP2305686A1, 6129-EP2308479A2, 6129-EP2308510A1, 6129-EP2308562A2, 6129-EP2308828A2, 6129-EP2308838A1, 6129-EP2308839A1, 6129-EP2308844A2, 6129-EP2308845A2, 6129-EP2308846A2, 6129-EP2308848A1, 6129-EP2308854A1, 6129-EP2308857A1, 6129-EP2308858A1, 6129-EP2308861A1, 6129-EP2308874A1, 6129-EP2308877A1, 6129-EP2308879A1, 6129-EP2308880A1, 6129-EP2308926A1, 6129-EP2311453A1, 6129-EP2311801A1, 6129-EP2311802A1, 6129-EP2311803A1, 6129-EP2311807A1, 6129-EP2311815A1, 6129-EP2311816A1, 6129-EP2311817A1, 6129-EP2311822A1, 6129-EP2311823A1, 6129-EP2311827A1, 6129-EP2311834A1, 6129-EP2311837A1, 6129-EP2311840A1, 6129-EP2314576A1, 6129-EP2314582A1, 6129-EP2314585A1, 6129-EP2314587A1, 6129-EP2314590A1, 6129-EP2316831A1, 6129-EP2316937A1, 6129-EP2371809A1, 6129-EP2371811A2, 6129-EP2371814A1, 6129-EP2380568A1, 6129-EP2380873A1, C11143, D01043, Dimethyl sulfoxide solution, 50 wt. % in H2O, Dimethyl sulfoxide, >=99.6%, ReagentPlus(R), Dimethyl sulfoxide, ReagentPlus(R), >=99.5%, 25534-EP2272846A1, 25534-EP2275422A1, 25534-EP2277868A1, 25534-EP2277869A1, 25534-EP2277870A1, 25534-EP2284166A1, 25534-EP2287164A1, 25534-EP2292608A1, 25534-EP2298076A1, 25534-EP2298077A1, 25534-EP2298769A1, 25534-EP2298773A1, 25534-EP2301353A1, 25534-EP2305031A1, 25534-EP2305034A1, 25534-EP2305035A1, 25534-EP2308866A1, 25534-EP2308878A2, 25534-EP2314580A1, 25534-EP2374784A1, 25534-EP2374785A1, 25534-EP2374791A1, 44657-EP2272517A1, 44657-EP2281819A1, 44657-EP2287153A1, 44657-EP2292615A1, 44657-EP2298746A1, 44657-EP2298761A1, 44657-EP2301928A1, 44657-EP2305250A1, 44657-EP2305659A1, 44657-EP2311818A1, 52178-EP2284172A1, 52178-EP2287153A1, 52178-EP2292228A1, 52178-EP2292615A1, 52178-EP2292621A1, 52178-EP2292622A1, 52178-EP2295426A1, 52178-EP2295427A1, 52178-EP2301928A1, 52178-EP2301929A1, 52178-EP2301935A1, 52178-EP2305674A1, 52178-EP2305684A1, 52178-EP2305685A1, 52178-EP2305686A1, 52178-EP2308844A2, 52178-EP2308845A2, 52178-EP2308846A2, 61519-EP2270006A1, 61519-EP2308848A1, 68881-EP2270006A1, 68881-EP2277867A2, 68881-EP2280003A2, 68881-EP2292595A1, 68881-EP2308861A1, AB01563146_01, Dimethyl sulfoxide, p.a., ACS reagent, 99.9%, Dimethyl sulfoxide, SAJ first grade, >=99.0%, 300067X, Dimethyl sulfoxide, JIS special grade, >=99.0%, Dimethyl sulfoxide, Vetec(TM) reagent grade, 99%, Dimethyl sulfoxide, UV HPLC spectroscopic, 99.9%, Dimethyl sulfoxide, anhydrous, ZerO2(TM), >=99.9%, I14-14298, Dimethyl sulfoxide, meets EP, USP testing specifications, Dimethyl sulfoxide, ACS spectrophotometric grade, >=99.9%, Dimethyl sulfoxide, puriss. p.a., dried, <=0.02% water, (Methyl sulfoxide)-d6; DMSO-d6; Hexadeuterodimethyl sulfoxide, Dimethyl sulfoxide, >=99.5% (GC), plant cell culture tested, Dimethyl sulfoxide, BioUltra, for molecular biology, >=99.5% (GC), Dimethyl sulfoxide, European Pharmacopoeia (EP) Reference Standard, Dimethyl sulfoxide, puriss. p.a., ACS reagent, >=99.9% (GC), Dimethyl sulfoxide, Vetec(TM) reagent grade, anhydrous, >=99.7%, Dimethyl sulfoxide, >=99.0%, suitable for absorption spectrum analysis, Dimethyl sulfoxide, United States Pharmacopeia (USP) Reference Standard, Dimethyl sulfoxide, for inorganic trace analysis, >=99.99995% (metals basis), Dimethyl sulfoxide, meets EP testing specifications, meets USP testing specifications, 103759-08-6, 164071-41-4, 705301-21-9, 8070-53-9, Dimethyl sulfoxide, Hybri-Max(TM), sterile-filtered, BioReagent, suitable for hybridoma, >=99.7%, Dimethyl sulfoxide, puriss., absolute, over molecular sieve (H2O <=0.005%), >=99.5% (GC), Dimethyl sulfoxide, sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

ID: 40

InChIKey: IXFPJGBNCFXKPI-FSIHEZPISA-N
SMILES: CCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O

biological descriptors:

CFTR relevance: no effect on maturation

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"AM Van Heeckeren" "ML Drumm" "RC Boucher" "JR Riordan" "A Mengos" "M Gentzsch" "MR Knowles" "SH Randell" "SE Gabriel" "BR Grubb"

CID is 446378
synonyms found at PubChem are:
thapsigargin, 67526-95-8, UNII-Z96BQ26RZD, Z96BQ26RZD, CHEMBL96926, CHEBI:9516, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OXY]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-((2-methyl-1-oxo-2-butenyl)oxy)-2-oxo-4-(1-oxobutoxy)azuleno(4,5-b)furan-7-yl ester, (3S-(3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha))-, TG1, SR-01000076181, (-)-Thapsigargin, Octanoic Acid [3s-[3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha(Z), 9balpha]]-6-(Acetyloxy)-2,3,-3a,4,5,6,6a,7,8,9b-Decahydro-3,3a-Dihydroxy-3,6,9-Trimethyl-8-[(2-Methyl-1-Oxo-2-Butenyl)oxy]-2-Oxo-4-(1-Oxobutoxy)-Azuleno[4,5-B]furan-7-Yl Ester, Octanoic Acid [3s-[3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha(Z), 9balpha]]-6-(Acetyloxy)-2,3,-3a,4,5,6,6a,7,8,9b-Decahydro-3,3a-Dihydroxy-3,6,9-Trimethyl-8-[(2-Methyl-1-Oxo-2-Butenyl)oxy]-2-Oxo-4-(1-Oxobutoxy)-Azuleno[4,5-B]furan-7-Yl Ester, THAPSINGARGIN, AC1L9JLO, Azuleno[4,5-b]furan, octanoic acid deriv., n-7-yl ester (9CI), D02KGR, Lopac0_001262, SCHEMBL82423, BSPBio_001501, MLS006010944, GTPL5351, CHEBI:93212, MolPort-003-959-790, HMS1361L03, HMS1791L03, HMS1989L03, HMS3263N06, HMS3402L03, ZINC8195655, Tox21_501262, BDBM50035612, C28H38O12.C7H16, MFCD00083511, AKOS024456410, CCG-205336, LMPR0103410001, LP01262, IDI1_033971, NCGC00016060-08, NCGC00162381-05, NCGC00162381-06, NCGC00261947-01, SMR001456557, LS-176600, Thapsigargin, >=98% (HPLC), solid film, B6614, EU-0101262, C09561, T 9033, alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]]-, SR-01000076181-1, SR-01000076181-5, BRD-K69023402-001-02-5, I14-60634, (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6- (Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2H,3H,3aH,4H,5H,6H,6aH,7H,8H,9bH-azuleno[4,5-b]furan-7-yl octanoate, [(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-acetyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-[(Z)-2-methylbut-2-enoyl]oxy-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] octanoate, Octanoic Acid (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b- decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl Ester, Octanoic Acid [3S-[3|A,3a|A,4|A,6|A,6a|A,7|A,8|A(Z),9b|A]]-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl Ester, octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester, octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(-oxobutoxy)azuleno[4,5-b]furan, Octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]fura, Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester, [3S-[3alpha,3abeta,4

ID: 41

InChIKey: IYRMWMYZSQPJKC-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

biological descriptors:

CFTR relevance: influence of intracellular CFTR distribution

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment ER & Golgi (Translation, quality control, trafficking, PTM)

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"AD Floyd" "PL Zeitlin" "E Kwon" "M Lim" "K McKenzie"

CID is 5280863
synonyms found at PubChem are:
kaempferol, 520-18-3, Kempferol, Kaempherol, Populnetin, Rhamnolutein, Robigenin, Trifolitin, Pelargidenolon, Rhamnolutin, Swartziol, 3,4',5,7-Tetrahydroxyflavone, Indigo Yellow, Kampherol, Campherol, Kampferol, Nimbecetin, Kaemferol, 5,7,4'-Trihydroxyflavonol, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Pelargidenolon 1497, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, C.I. 75640, CCRIS 41, NSC 407289, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, Flavone, 3,4',5,7-tetrahydroxy-, NSC 656277, UNII-731P2LE49E, EINECS 208-287-6, CHEMBL150, BRN 0304401, AI3-36096, CHEBI:28499, IYRMWMYZSQPJKC-UHFFFAOYSA-N, 731P2LE49E, 3,4′,5,7-Tetrahydroxyflavone, NSC656277, NSC-407289, NSC-656277, CAS-520-18-3, DSSTox_CID_768, DSSTox_RID_75781, DSSTox_GSID_20768, Q-100584, SMR000112585, Pelargidenon, Kampcetin, 3,5,7,4'-Tetrahydroxyflavone, HSDB 7703, 4det, Kaempferol,(S), AC1NQXP1, 5,4'-Trihydroxyflavonol, Prestwick0_001098, Prestwick1_001098, Prestwick2_001098, Prestwick3_001098, D0G3TK, 3,5,7-Tetrahydroxyflavone, 4',5,7-trihydroxyflavonol, BIDD:PXR0073, Oprea1_650954, SCHEMBL18817, BSPBio_001176, 5-18-05-00251 (Beilstein Handbook Reference), MLS000697730, MLS001055391, MLS001074884, MLS006010737, BIDD:ER0134, SPBio_003058, 3,4,5,7-Tetrahydroxyflavone, Kaempferol, analytical standard, BDBM7462, BPBio1_001294, MEGxp0_001283, DTXSID7020768, Flavone,4',5,7-tetrahydroxy-, ACon1_001867, cid_5280863, CHEBI: 28499, MolPort-001-741-568, HMS1571K18, HMS2098K18, HMS2267I09, HMS3656M03, KAEMPFEROL ROBIGENIN; 3,4',5,7-TETRAHYDRO-XY-FLAVONE, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1- benzopyran-4-one, Kaempferol, >=97.0% (HPLC), TNP00039, ZINC3869768, Tox21_201165, Tox21_303363, AC-544, CK0011, GP7425, HSCI1_000027, LMPK12110003, LS-176, MFCD00016938, NSC407289, s2314, SBB066091, Kaempferol solution, 20 mM in DMSO, AKOS015895240, Kaempferol, >=90% (HPLC), powder, CCG-202823, CS-1273, DB01852, GS-3570, MCULE-8965218413, NCGC00016480-01, NCGC00016480-02, NCGC00016480-03, NCGC00016480-04, NCGC00016480-05, NCGC00016480-06, NCGC00016480-07, NCGC00016480-09, NCGC00091036-01, NCGC00091036-02, NCGC00164322-01, NCGC00179275-01, NCGC00179275-02, NCGC00257464-01, NCGC00258717-01, AN-15750, BC215517, CC-29746, HY-14590, KB-79581, SC-17291, ST030560, AB0010534, TR-018501, AB00514046, FT-0614420, K0018, N1719, W1682, 3,4',5,7-tetrahydroxy-Flavone (7CI,8CI), C05903, J10449, Kaempferol, disposable screening library format, S00111, W-2776, Flavone, 3,4',5,7-tetrahydroxy- (7CI,8CI), 520K183, A828886, C-18018, SR-01000765646, I06-0240, Kaempferol, primary pharmaceutical reference standard, SR-01000765646-3, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-chromen-4-one, BRD-K12807006-001-05-2, BRD-K12807006-001-10-2, 2-(4-hydroxyphenyl)-3,5,7-tris(oxidanyl)chromen-4-one, 3,4',5,7-tetrahydroxyflavone solution, 20 mM in DMSO, A91A6666-86C8-4B33-B3EF-F74CD3CD7F47, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one #, 3,5,7-Trihydroxy-2-[4-hydroxy-phenyl]-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, 4H-1-Benzopyran-4-one,5,7-trihydroxy-2-(4-hydroxyphenyl)-, Kaempferol, United States Pharmacopeia (USP) Reference Standard, 3,5,7-Trihydroxy-2-[4-hydroxy- phenyl]-4H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)- (9CI), 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one solution, 20 mM in DMSO, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-5,7,4'-Trihydroxyflavonol

ID: 42

InChIKey: JIMHYXZZCWVCMI-RIYZIHGNSA-N
SMILES: C1=CC(=CC(=C1)N2C(=O)/C(=C\C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"SM Rowe" "BA Woodworth" "SB Hicks" "D Skinner" "BT Conger" "S Zhang" "EJ Sorscher"

"H Yang" "S Lin" "TH Ma" "LN Xu" "X Liu" "SG Hou" "WL Na"

CID is 1554210
synonyms found at PubChem are:
CFTR Inhibitor 172, C18H10F3NO3S2, 307510-92-5, CFTRinh 172, CFTR(inh)-172, 4-[(E)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid, CFTRinh-172, CFTRinh - 172, AC1LT95D, CFTR-172, SCHEMBL1881897, CHEMBL1554655, 5-[(4-Carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl-4-thiazolidinone, 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone, MolPort-008-130-993, MolPort-028-751-092, 4-[4-oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-(5z)-ylidenemethyl]-benzoic acid, 4-[4-OXO-2-THIOXO-3-(3-TRIFLUOROMETHYL-PHENYL)-THIAZOLIDIN-5-YLIDENEMETHYL]-BENZOIC ACID, 2313AH, s7139, ZINC13829351, AKOS003140113, NCGC00165765-01, KB-41399, BB0220685, BB 0220685, CFTR(inh)-172, >=98% (HPLC), powder, 4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid, 4-{[(5E)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl}benzoic acid, benzoic acid, 4-[[4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]-

ID: 43

InChIKey: JIMHYXZZCWVCMI-ZSOIEALJSA-N
SMILES: C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"SM Rowe" "BA Woodworth" "SB Hicks" "D Skinner" "BT Conger" "S Zhang" "EJ Sorscher"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 1554208
synonyms found at PubChem are:
CFTRinh-172, CFTR(inh)-172, CFTR Inhibitor-172, 307510-92-5, CHEMBL461939, 3-[(3-Trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone, CFTRinh 172, 4-[4-oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-(5z)-ylidenemethyl]-benzoic acid, CFinh-172, CFTR Inh-172, AC1LT95A, AOB6719, 5-[(4-Carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl-4-thiazolidinone, JIMHYXZZCWVCMI-ZSOIEALJSA-N, MolPort-000-501-417, ZINC966859, BDBM50244767, MFCD06411408, STL032754, AKOS000365470, CS-3185, BAS 00786641, HY-16671, BIM-0044592.P001, ST50148666, EC-000.1908, Z-2135, J-018109, 4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid, 4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid, 4-[4-Oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-5Z)-ylidenemethyl]-benzoic acid, (Z)-4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid, 4-({4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}met hyl)benzoic acid, 4-[(Z)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid, 4-[(Z)-{4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, 4-{[(5Z)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl}benzoic acid

ID: 44

InChIKey: JUVIOZPCNVVQFO-HBGVWJBISA-N
SMILES: CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6758
synonyms found at PubChem are:
rotenone, 83-79-4, Dactinol, Paraderil, (-)-Rotenone, Tubatoxin, Barbasco, (-)-cis-Rotenone, Derrin, Derris, Cube root, Nicouline, Rotocide, Noxfish, Ronone, Rotenon, Canex, Deril, Liquid Derris, Cube-Pulver, Dri-Kil, Rotessenol, Noxfire, Rotefive, Rotefour, Rotenox, Cubor, Haiari, Mexide, Derris root, Powder and root, Chem-Mite, Pro-nox fish, Cenol garden dust, Curex flea duster, Prenfish, Tubotoxin, Gerane, Prentox, Ro-Ko, Synpren, Derris (insecticide), Chem fish, Pb-nox, Rotenox 5EC, 5'-beta-Rotenone, Green Cross Warble Powder, Chem-Fish Synergized, Prentox Synpren-Fish, Nekoe, Caswell No. 725, Extrax, Cube extract, Foliafume E.C., Fish-Tox, ENT 133, Rotenona [Spanish], Rotenone, commercial, CCRIS 895, Rotenone [BSI:ISO], HSDB 1762, NCI-C55210, 5'beta-Rotenone, EPA Pesticide Chemical Code 071003, UNII-03L9OT429T, AI3-00133, NSC26258, EINECS 201-501-9, NSC 26258, Rotenona, Derris resins, MLS000738056, CHEMBL429023, CHEBI:28201, 03L9OT429T, Rotacide E.C., CUBE, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-alpha-isopropenyl-8,9-dimethoxy-, (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one, (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, (2R-(2alpha,6aalpha,12aalpha))-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)(1)benzopyrano(3,4-b)furo(2,3-h)benzopyran-6(6aH)-one, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12aalpha-Tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, NCGC00017358-05, DSSTox_CID_1248, DSSTox_RID_76038, DSSTox_GSID_21248, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R-(2alpha,6aalpha,12aalpha))-, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-on, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one, Green cross warble, Rotacide, Protax, 5'.beta.-Rotenone, CAS-83-79-4, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, (2R,6aS,12aS)-1,2,6,6a,12,12a- hexahydro-2-isopropenyl-8,9- dimethoxychromeno[3,4-b] furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno(3,4-b)furo(2,3-h)chromen-6-one, (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno[3,4-b]furo[2,3-h]chromen-6-one, (2R,6aS,12aS)-2-isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-, SR-01000076110, Foliafume, Rotenoid, Roteonone, Nusyn, rote five, WLN: T G5 D6 B666 CV HO MO POT&TT&J IY1&U1 SO1 TO1, Chem-Fish, Foliafume E.C, Rotacide E.C, 5''beta-rotenone, 5'b-Rotenone, Rotocide E.C., (1)Benzopyrano[3,3-h](1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-iospropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6a.alpha.H)-one, 1,2,12,12a.alpha.-tetrahydro-2.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2.alpha.,6a.alpha.,12a.alpha.)]-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2alpha,6aalpha,12aalpha)]-, Derris, JMAF, Prestwick_542, Hydrogenated rotenone, Rotenone (7CI), Rotenone, hydrogenated, Rotenone, >=95%, Spectrum_000065, Spectrum2_000457, Spectrum3_000158, Spectrum4_001638, Spectrum5_000455, D0F7CS, AC1L1N8M, AC1Q4EW8, Lopac0_001112, SCHEMBL42253, BSPBio_001896, isopropenyl(dimethoxy)[?]one, KBioGR_002075, KBioSS_000465, SPECTRUM200013, DivK1c_000947, Rotenone E.C. (7.5%), SPBio_000534, DTXSID6021248, HMS502P09, KBio1_000947, KBio2_000465, KBio2_003033, KBio2_005601, KBio3_001116, inhibits NADH2 oxidation to NAD, NSC8505, JUVIOZPCNVVQFO-HBGVWJBISA-N, MolPort-002-507-351, NINDS_000947, HMS3263O06, 2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-H]chromen-6(6ah)-one, BCP07278, HY-B1756, NSC-8505, TNP00301, ZINC3860715, Tox21_110819, Tox21_201904, Tox21_300695, Tox21_501112, 2901AC, BDBM50135527, CCG-39886, LMPK12060007, MFCD09025614, NSC-26258, SBB006465, AKOS004910398, Tox21_110819_1, API0004105, CS-6067, DB11457, LP01112, LS-1830, MCULE-7287067191, MCULE-7415617623, RL05168, SDCCGMLS-0066415.P001, IDI1_000947, NCGC00017358-01, NCGC00017358-02, NCGC00017358-03, NCGC00017358-04, NCGC00017358-06, NCGC00017358-07, NCGC00017358-08, NCGC00017358-09, NCGC00017358-10, NCGC00017358-11, NCGC00017358-14, NCGC00017358-15, NCGC00094382-01, NCGC00094382-02, NCGC00094382-03, NCGC00094382-04, NCGC00094382-05, NCGC00254603-01, NCGC00259453-01, NCGC00261797-01, AJ-46043, AK115691, AN-24066, AS-10183, NCI60_002093, SC-66514, SMR000393729, ST057261, AX8150549, ST2413787, EU-0101112, R0090, Rotenone, PESTANAL(R), analytical standard, TRANSGENIC MODEL EVALUATION (ROTENONE), C07593, R 8875, 26914-EP2275422A1, 26914-EP2280009A1, 26914-EP2305662A1, 26914-EP2308857A1, 26914-EP2314583A1, 599T610, SR-01000076110-2, SR-01000076110-5, SR-01000076110-6, W-104134, BRD-K08316444-001-01-9, BRD-K08316444-001-05-0, ROTENONE (SEE ALSO TRANSGENICMODEL EVALUATION (ROTENONE)), (1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0^{3,11}.0^{4,8}.0^{14,19}]henicosa-3(11),4(8),9,14(19),15,17-hexaen-12-one, (2R,6a5,12axS)-1,2,12,12a-tetrahydro-2a-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-H)(1)benzopyran-6(6aH)-one, (2r,6as,12as)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxybenzopyrano(3,4-b)furo(2,3-h)benzopyran-6-one, (2R-(6aalpha,12aalpha)-1,2-Dihydro-2-isopropenyl-8,9-dimethoxychromano(3,4-b)furo(2,3-h)chroman-6-one, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-.alpha.-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-isopropenyl-8,9-dimethoxy-, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy- (8CI), [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)- (9CI), [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-o ne, [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h) (1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, (2R-(2alpha, 6alpha-12aalpha))-, 1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 9CI, 12679-58-2, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-on e, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, ([2.2.1]R-([2.2.1]alpha,6aalpha,[2.2.1][2.2.1]aalpha))-, Tubatoxin 1,2,12,12a,-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]-benzopyran-6(6aH)-one

ID: 45

InChIKey: JZJXEPNQMCFBIS-UHFFFAOYSA-N
SMILES: C=CC1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=CC=C3

biological descriptors:

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

"Y Wang" "MC Bartlett" "DM Clarke" "TW Loo"

CID is 683025
synonyms found at PubChem are:
Corr-2b, AC1LEAGY, SCHEMBL837831, ZINC48933, ST007156, EU-0084361, Phenyl-[4-(4-vinyl-phenyl)-thiazol-2-yl]-amine, SR-01000511692, 4-(4-ethenylphenyl)-N-phenyl-1,3-thiazol-2-amine, phenyl[4-(4-vinylphenyl)(1,3-thiazol-2-yl)]amine, SR-01000511692-1, A0861/0040368

ID: 46

InChIKey: LAZPBGZRMVRFKY-HNCPQSOCSA-N
SMILES: C1CSC2=N[C@H](CN21)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 27944
synonyms found at PubChem are:
Levamisole hydrochloride, 16595-80-5, Levamisole HCl, Ergamisol, Tramisol, Tramisole, Decaris, (-)-Tetramisole hydrochloride, (S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, Niratic hydrochloride, Ascaridil, Dekaris, Levacide, Levadin, Levasole, Solaskil, Meglum, Nilverm forte, Worm-chek, Stimamizol hydrochloride, Ripercol-L, Citarin L, Niratic-puron hydrochloride, Levomysol hydrochloride, (-)-Tetramisole, Levamisole (hydrochloride), KW 2LE-T, Nemicide, Spartakon, KW-2-LE-T, NSC-177023, UNII-DL9055K809, EINECS 240-654-6, L-Tetramisole hydrochloride, R 12564, R 12,564, R-12,564, C11H12N2S.HCl, Levamisol hydrochloride, CHEBI:6433, (6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride, DL9055K809, Ergamisol (TN), (-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride, L-(-)-2,3,5,6-Tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride, DSSTox_CID_27518, DSSTox_RID_82391, Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-, DSSTox_GSID_47518, 74191-78-9, (S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, L(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride, Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-, SMR001230807, NSC177023, SR-01000075969, L-tetramisol, R-12564, (-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Hydrochloride, Levamisole hydrochloride [USAN], LEV hydrochloride, (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride, NCGC00094446-03, Prestwick_294, Levamisole hydrochloride [USAN:USP], AC1L1EAA, Levamisole HCl(Ergamisol), Ergamisol (TN) (Janssen), CAS-16595-80-5, CHEMBL1770, SCHEMBL19226, BMK1-H6, Levamisole Hydrochloride,(S), Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, MLS002153440, MLS002222198, MLS002695941, SPECTRUM1503245, Levamisole hydrochloride (USP), ((-)-Tetramisole hydrochloride, DTXSID7047518, CTK8B8704, KS-00000GHI, LAZPBGZRMVRFKY-HNCPQSOCSA-N, MolPort-003-666-467, HMS1568F05, HMS1922M11, 14769-73-4 (Parent), BCP13755, Levamisole Hydrochloride (Ergamisol), Tox21_111282, Tox21_500690, ANW-61085, CCG-40301, MFCD00012675, s1939, AKOS015951350, Tox21_111282_1, CS-2372, EBD2199095, KW-2299, LP00690, MCULE-7118728152, NE43217, RTR-030849, NCGC00094046-01, NCGC00261375-01, NCGC00263461-01, AC-23973, AS-13370, BC201679, HY-13666, I013, LS-80641, SC-26016, AB0013424, AB1009509, TL8001274, EU-0100690, FT-0625516, L0231, ST24026614, (-)-Tetramisole hydrochloride, >=99% (GC), C07906, D00750, L 9756, J-010244, J-521642, SR-01000075969-1, SR-01000075969-6, Z1550648764, Levamisol hydrochloride, VETRANAL(TM), analytical standard, UNII-0NDK265MCV component LAZPBGZRMVRFKY-HNCPQSOCSA-N, Levamisole Hydrochloride 1.0 mg/ml in Methanol (as free base), Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-, Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-, (-)-2,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride, (7S)-7-phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene hydrochloride, Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-, Levamisole hydrochloride, European Pharmacopoeia (EP) Reference Standard, (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride, Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-, Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI), Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (6S)-, Levamisole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Levamisole hydrochloride, United States Pharmacopeia (USP) Reference Standard, (S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride; L(-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole hydrochloride; Levamisole hydrochloride, 24593-45-1, 39170-95-1, Levamisole hydrochloride for system suitability, European Pharmacopoeia (EP) Reference Standard, AKOS015898619, I09-1966

ID: 47

InChIKey: LZCOBWKVDSSOBB-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC3=C2OC(=CC3=O)C4=CC=NC=C4

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"MJ Kurth" "MF Springsteel" "MH Nantz" "L Al-Nakkash"

CID is 3163532
synonyms found at PubChem are:
2-Pyridin-4-yl-benzo[h]chromen-4-one, UCCF-029, 2110-25-0, CHEMBL177991, 2-(pyridin-4-yl)-4H-benzo[h]chromen-4-one, BAS 12813734, AC1MKUU0, D0T9DI, MLS001209162, GTPL4335, SCHEMBL4069839, ZINC9006, CTK7H2722, DTXSID20390354, CHEBI:116557, HMS2841G23, BDBM50159612, 2-(4-pyridyl)benzo[h]chromen-4-one, 2-pyridin-4-ylbenzo[h]chromen-4-one, AKOS000507523, MCULE-4590967836, 2-(pyridin-4-yl)benzo[h]chromen-4-one, SMR000525005, TR-043515, ST50294170, EC-000.1914, 4-(4-Oxo-4H-benzo[h]chromen-2-yl)-pyridinium, J-013846, 4-(4-Oxo-4H-benzo[h]chromen-2-yl)-pyridinium bisulfate

ID: 48

InChIKey: MBRLOUHOWLUMFF-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"H Yang" "S Lin" "TH Ma" "LN Xu" "X Liu" "SG Hou" "WL Na"

CID is 10228
synonyms found at PubChem are:
Osthole, Osthol, 484-12-8, Ostol, Ostole, 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one, 7-Methoxy-8-isopentenylcoumarin, 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-, 8-(3-Methyl-2-butenyl)herniarin, 7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one, 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, UNII-XH1TI1759C, NSC 31868, 7-METHOXY-8-(3-METHYL-2-BUTENYL)-COUMARIN, 7-methoxy-8-(3-methyl-2-butenyl)coumarin, Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-, CHEMBL52229, XH1TI1759C, CHEBI:69832, C15H16O3, NSC31868, 7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one, Q-100535, 7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one, SMR000156202, Osthole (Osthol), Osthole,(S), Cnidium Fruit Extract, Spectrum_001542, SpecPlus_000946, Spectrum2_000723, Spectrum3_001645, Spectrum4_001687, Spectrum5_000334, AC1L1UR5, Osthole, analytical standard, Oprea1_642606, Oprea1_873803, SCHEMBL50436, BSPBio_003369, KBioGR_001954, KBioSS_002022, ZINC566, MLS000574904, MLS001048988, MLS006011425, DivK1c_007042, SPECTRUM1504165, SPBio_000646, MEGxp0_000155, ACon1_002155, CTK7A8592, KBio1_001986, KBio2_002022, KBio2_004590, KBio2_007158, KBio3_002589, DTXSID20197507, MBRLOUHOWLUMFF-UHFFFAOYSA-N, MolPort-000-881-851, HMS2267O21, HMS3656A07, BCP10832, EBD33224, HY-N0054, KS-00000N3A, ANW-50075, BBL013019, BDBM50240512, CCG-40172, CO0040, MFCD00076049, NSC-31868, s2337, STK396321, AKOS000277663, AC-8041, AN-8395, CS-2125, DS-0881, MCULE-5691054147, RP28651, RTR-017689, SDCCGMLS-0066780.P001, NCGC00095694-01, NCGC00095694-02, NCGC00095694-03, NCGC00095694-05, WLN: T66 BOVJ IO1 J2UY1&1, 4CN-0704, AJ-07908, AK-35300, BAS 00015470, BR-35300, CC-33366, CJ-00015, LS-55250, ZB000125, AB0021820, AX8007596, KB-250032, ST2412572, TR-017689, FT-0082540, FT-0601535, N1825, O0426, ST50909221, W1256, C09280, J10077, S-3211, 484O128, A827530, C-14815, Osthole, primary pharmaceutical reference standard, SR-01000721624, I06-0435, SR-01000721624-4, BRD-K78294846-001-03-3, 7-Methoxy-8-(3-methyl-2-butenyl)-2H-chromen-2-one #, 7-methoxy-8-(3-methylbut-2-enyl)-1-benzopyran-2-one, Osthole, European Pharmacopoeia (EP) Reference Standard, 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)- (9CI), 1440642-68-1, InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H

ID: 49

InChIKey: MUNWAHDYFVYIKH-RITPCOANSA-N
SMILES: C[N+]1(C[C@@H](C[C@H]1C(=O)[O-])O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 164642
synonyms found at PubChem are:
Betonicine, 515-25-3, (-)-Betonicine, Achillein, trans-4-hydroxy-L-proline betaine, UNII-FBA654632Q, 4-hydroxy-stachydrine, FBA654632Q, (2S-trans)-2-Carboxylato-4-hydroxy-1,1-dimethylpyrrolidinium, 4-Hydroxy-1,1-dimethylpyrrolidinium-2-carboxylate, (2,4R)-4-hydroxy-1,1-dimethylpyrrolidinium-2-carboxylate, Achilleine, (2s,4r)-4-Hydroxy-1,1-Dimethylpyrrolidinium-2-Carboxylate, (2S,4R)-4-hydroxy-1,1-dimethylpyrrolidin-1-ium-2-carboxylate, l-4-hydroxystachydrine, Betonicin, EINECS 208-195-6, NSC 655264, 4-Hydroxyproline betaine, L-4-Hydroxyproline betaine, trans-hydroxyproline betaine, AC1Q5BF7, SCHEMBL893616, AC1L4V67, Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2S,4S)-, CHEBI:85533, FCH3878294, CC-24644, Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, hydroxide, inner salt, (2S-trans)-, C08269, C-25726, (2S,4R)-4-hydroxy-1,1-dimethyl-pyrrolidin-1-ium-2-carboxylic acid, 4476-22-6

ID: 50

InChIKey: NBLBCGUCPBXKOV-UHFFFAOYSA-N
SMILES: CC(C)CN1C2=C(C(=O)N(C1=O)C)NC(=N2)COC

biological descriptors:

CFTR relevance: Phosphodiesterase 1 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"KL Hamilton" "PC Chao"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 155806
synonyms found at PubChem are:
78033-08-6, 8-Methoxymethyl-IBMX, 8-methoxymethyl-3-isobutyl-1-methylxanthine, MMPX, 3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione, 8-METHOXYMETHYL-1-METHYL-3-(2-METHYLPROPYL)XANTHINE, CHEMBL307639, IN1237, MI-methylxanthine, 1H-Purine-2,6-dione, 3,7-dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-, 8MM-IBMX, 8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione, 3-isobutyl-8-methoxymethyl-1-methylxanthine, SR-01000075985, Tocris-0552, AC1Q4FLL, Lopac-M-2547, Lopac0_000764, BSPBio_001462, KBioGR_000182, KBioSS_000182, MLS002153423, SCHEMBL782824, AC1L4F09, SCHEMBL9927457, CHEBI:92940, CTK7B2646, KBio2_000182, KBio2_002750, KBio2_005318, KBio3_000363, KBio3_000364, DTXSID30228679, MolPort-003-848-632, Bio2_000182, Bio2_000662, HMS1361J04, HMS1791J04, HMS1989J04, HMS2230A04, HMS3262I10, HMS3266K14, HMS3373L09, HMS3402J04, Tox21_500764, 2228AC, ANW-54494, BDBM50059035, HSCI1_000291, MFCD00211081, ZINC14806781, AKOS016001307, AKOS024458560, CCG-204849, LP00764, 3,7-Dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, IDI1_033932, NCGC00015658-01, NCGC00015658-02, NCGC00015658-03, NCGC00015658-04, NCGC00015658-05, NCGC00015658-06, NCGC00015658-07, NCGC00015658-08, NCGC00024647-01, NCGC00024647-02, NCGC00024647-03, NCGC00024647-04, NCGC00024647-05, NCGC00261449-01, AJ-65376, CC-23404, SMR001230798, AX8000924, DB-056279, B6348, EU-0100764, FT-0641660, M 2547, A839315, C-16701, SR-01000075985-1, SR-01000075985-3, 8-Methoxymethyl-3-isobutyl-1-methylxanthine, >=98%, BRD-K53878242-001-02-4, BRD-K56077740-001-03-5, 8-Methoxymethyl-1-Methyl-1-3-(2-Methylpropyl)Xanthine, 3-Isobutyl-8-methoxymethyl-1-methyl-3,7-dihydro-purine-2,6-dione, 3-Isobutyl-8-methoxymethyl-1-methyl-3,9-dihydro-purine-2,6-dione

ID: 51

InChIKey: NCNXULVCMORARX-NYMFISLZSA-N
SMILES: C[C@@]12CCC3[C@]4(C=C[C@H](C(C4CC(=O)O[C@]3(C1=CC(=O)O[C@H]2C5=COC=C5)C)(C)C)O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708582
synonyms found at PubChem are:
DEOXYANDIROBIN LACTONE, KBio2_003732, Spectrum_000684, SpecPlus_000167, Spectrum2_000257, Spectrum3_000049, Spectrum4_001331, Spectrum5_000201, BSPBio_001777, KBioGR_001821, KBioSS_001164, DivK1c_006263, SPBio_000074, CHEMBL3039179, SCHEMBL12998316, KBio1_001207, KBio2_001164, KBio2_006300, KBio3_000937, NCGC00179013-01, SR-05000002674, SR-05000002674-1, BRD-A58269583-001-02-0

ID: 52

InChIKey: NHTGHBARYWONDQ-JTQLQIEISA-N
SMILES: C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441350
synonyms found at PubChem are:
METYROSINE, 672-87-7, Metirosine, alpha-Methyl-L-tyrosine, (S)-alpha-Methyltyrosine, Demser, Methyltyrosine, alpha-Methyltyrosine, L-alpha-Methyltyrosine, Metirosina, Metirosinum, L-alpha-Methyl-p-tyrosine, Alpha-Methyl-L-P-Tyrosine, (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid, L-Metyrosine, (-)-alpha-Methyl-L-tyrosine, (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid, UNII-DOQ0J0TPF7, ALPHA-METHYL-L-TYR, L(-)-Metyrosine, MK 781, alpha-Methyl-p-tyrosine, L-AMPT, MK-781, DOQ0J0TPF7, A-METHYL-L-TYROSINE, L-2-ME-TYR-OH, CHEBI:6912, (S)-2-(4-Hydroxybenzyl)-2-aminopropanoic Acid, NCGC00094144-03, Metirosinum [INN-Latin], alpha-Methyl-para-tyrosine, DSSTox_CID_3315, Metirosina [INN-Spanish], L-2-METHYL-3-(4-HYDROXYPHENYL)ALANINE, DSSTox_RID_76972, DSSTox_GSID_23315, L-588357-0, Metirosine [INN], Metyrosine (USP), EINECS 211-599-5, Demser (TN), l-alpha-MT, a-methyl-L-p-tyrosine, CAS-672-87-7, alpha-methyl-paratyrosine, Metyrosine [USAN:USP], L 588357-0, (-)-(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropionsaeure, Metirosin, L-Tyrosine, alpha-methyl-, (-)-, alpha-Me-Tyr-OH, L-2-Methyl-3-(4-hydroxy-phenyl)alanine, L-?-Methyltyrosine, L-|A-Methyltyrosine, M 8131, L-Tyrosine, a-methyl-, (S)-|A-Methyltyrosine, A-METHYL-L-TYR, Metirosine (JAN/INN), L-|A-Methyl-p-tyrosine, Spectrum3_001846, H-A-ME-TYR-OH, H-(ME)TYR-OH, L-ALPHA-METHYLROSINE, AC1L9B0V, AC1Q29EO, Lopac0_000811, SCHEMBL50398, (S)-A-METHYLTYROSINE, BSPBio_003232, H-ALPHA-ME-L-TYR-OH, L-|A-MT, ZINC693, SPECTRUM2300312, GTPL6956, CHEMBL1200862, DTXSID6023315, KBio3_002732, MolPort-001-792-900, MolPort-044-812-316, NHTGHBARYWONDQ-JTQLQIEISA-N, HMS3262D03, Tox21_111253, Tox21_500811, MFCD00064201, Tox21_111253_1, AB02561, AM83582, CCG-204895, CM-2293, DB00765, FCH4035313, LP00811, MCULE-5340647798, NCGC00015701-06, NCGC00094144-01, NCGC00094144-04, NCGC00094144-05, NCGC00094144-06, NCGC00094144-07, NCGC00261496-01, AJ-07916, AK164271, alpha-Methyl-L-tyrosine, >=98% (TLC), AS-47139, CC-24015, CPD000466921, SAM001246895, AX8022058, TR-022622, EU-0100811, FT-0622266, (S)-ALPHA-METHYL-4-HYDROXYPHENYLALANINE, C07921, D00762, 672M877, A835693, C-23996, Z1617901128, UNII-X88TTO174Z component NHTGHBARYWONDQ-JTQLQIEISA-N, (2S)-2-azanyl-3-(4-hydroxyphenyl)-2-methyl-propanoic acid, Metyrosine, United States Pharmacopeia (USP) Reference Standard, (S)-2-AMINO-2-METHYL-3-(4'-HYDROXYPHENYL)PROPANOIC ACID, (S)-2-AMINO-3-(2-METHYL-4-HYDROXYPHENYL)PROPANOIC ACID, 23239-48-7, alpha-methyl-tyrosine, AC1OCG2D, ZB000155, (2S)-2-azaniumyl-3-(4-hydroxyphenyl)-2-methylpropanoate

ID: 53

InChIKey: NIDUTZAIIODVCH-FHNSGPDVSA-N
SMILES: CCC(C)C(C(=O)O[C@H]1[C@@H](C(C(=C)C2([C@@]1([C@@H](CC2=O)C3=COC=C3)C)O)[C@]4([C@H](CC(=O)O[C@](C4CC(=O)OC)(C)COC(=O)C)OC(=O)C)C)OC=O)OC(=O)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6710640
synonyms found at PubChem are:
PRIEURANIN ACETATE, KBio2_006186, Spectrum_000570, AC1O8JTI, Spectrum2_000243, Spectrum3_000024, Spectrum4_001305, Spectrum5_000089, BSPBio_001687, KBioGR_001709, KBioSS_001050, SPECTRUM100069, SPBio_000026, KBio2_001050, KBio2_003618, KBio3_000807, CHEBI:110188, CCG-39804, SDCCGMLS-0066356.P001, NCGC00179087-01, BRD-A64374397-001-02-6, [(3S,3aR,4R,5R)-6-[(2S,4R,5S)-5-acetyloxy-2-(acetyloxymethyl)-3-(2-methoxy-2-oxoethyl)-2,4-dimethyl-7-oxooxepan-4-yl]-5-formyloxy-3-(furan-3-yl)-7a-hydroxy-3a-methyl-7-methylidene-1-oxo-3,4,5,6-tetrahydro-2H-inden-4-yl] 2-acetyloxy-3-methylpentanoate

ID: 54

InChIKey: NPOJQCVWMSKXDN-UHFFFAOYSA-N
SMILES: COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2943
synonyms found at PubChem are:
Chlorthal-dimethyl, dacthal, 1861-32-1, DIMETHYL TETRACHLOROTEREPHTHALATE, Dacthalor, Fatal, Chlorthal-methyl, Tetral, Dimethyl 2,3,5,6-tetrachloroterephthalate, Tetrachloroterephthalic acid dimethyl ester, DAC 4, Chlorthal dimethyl ester, Daktal [Czech], Caswell No. 382, 1,4-Benzenedicarboxylic acid, 2,3,5,6-tetrachloro-, dimethyl ester, UNII-ZU3X5G2QLR, DCPA (VAN), Chlorthal dimethyl, 2,3,5,6-Tetrachloroterephthalic acid dimethyl ester, Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate, NSC 155745, Chlorthal-dimethyl [BSI:ISO], HSDB 358, DAC 893, EINECS 217-464-7, Terephthalic acid, tetrachloro-, dimethyl ester, ZU3X5G2QLR, EPA Pesticide Chemical Code 078701, BRN 1888840, AI3-52124, 2,3,5,6-Tetrachlorphthalsaure-dimethylester, Dimethyl tetrachloro-1,4-benzenedicarboxylate, CHEBI:34664, DAC-893, NPOJQCVWMSKXDN-UHFFFAOYSA-N, Dimethylester kyseliny tetrachlortereftalove [Czech], 2,3,5,6-Tetrachlorphthalsaure-dimethylester [German], FR-0596, NCGC00094521-05, DSSTox_CID_4000, DSSTox_RID_77254, DSSTox_GSID_24000, W-107783, Daktal, CAS-1861-32-1, methyl 2,3,5,6-tetrachloro-4-(methoxycarbonyl)benzoate, Diformic Acid Chlorotitanate, Chlorothal, C10H6Cl4O4, Dactal, CCRIS 9261, Chlorothal-methyl, PubChem20581, Spectrum_001803, ACMC-1CMRC, SpecPlus_000394, Dimethylester kyseliny tetrachlortereftalove, AC1L1ETN, Spectrum2_001876, Spectrum3_000817, Spectrum4_000657, Spectrum5_001944, SCHEMBL53477, BSPBio_002313, KBioGR_001033, KBioSS_002296, SPECTRUM330025, DivK1c_006490, SPBio_001752, AC1Q42F6, Jsp003807, CHEMBL1888079, DTXSID0024000, CTK8B1069, KBio1_001434, KBio2_002294, KBio2_004862, KBio2_007430, KBio3_001813, KS-00002WWL, MolPort-000-627-710, ZINC156678, HY-B2062, Tox21_300379, Tox21_400071, Vegetable turf and ornamental weeder, ANW-23263, CCG-39414, LS-953, NSC155745, SBB007929, AKOS002380307, WLN: 1OVR BG CG EG FG DVO1, ACM1861321, CS-5219, KS-5362, MCULE-3486663201, NSC-155745, RTR-008590, ACM20098413, Dimethyl 2,5,6-tetrachloroterephthalate, NCGC00094521-01, NCGC00094521-02, NCGC00094521-03, NCGC00094521-04, NCGC00094521-06, NCGC00094521-07, NCGC00254510-01, 2,5,6-Tetrachlorphthalsaure-dimethylester, AC-19871, AN-50004, CC-06682, SC-52602, Terechloroterephthalic acid dimethyl ester, ZB006419, DB-044581, Tetrachloroterephthalic acid, dimethyl ester, TR-008590, 1, 2,3,5,6-tetrachloro-, dimethyl ester, DACTHAL (PESTICIDE/FERTILIZERMIXTURE), FT-0625047, ST50409271, Dimethyl ester of tetrachloroterephthalic acid, 61D321, C14744, Chlorthal-dimethyl 10 microg/mL in Cyclohexane, Chlorthal-dimethyl 100 microg/mL in Cyclohexane, A813007, C-20067, DIMETHYL-2,3,5,6-TETRACHLOROTEREPHTHALATE, 2,5,6-Tetrachloroterephthalic acid, dimethyl ester, I01-8411, 2,3,5,6-Tetrachloroterephthalic acid, dimethyl ester, Chlorthal-dimethyl, PESTANAL(R), analytical standard, Dimethyl 2,5,6-tetrachloro-1,4-benzenedicarboxylate, Dimethyl 2,3,5,6-tetrachloro-1,4-benzenedicarboxylate, Terephthalic acid, 2,3,5,6-tetrachloro-,dimethyl ester, Chlorthal-dimethyl (RM, ISO Guide 34) 200 mg/L in n-Hexane, dimethyl 2,3,5,6-tetrakis(chloranyl)benzene-1,4-dicarboxylate, 2,3,5,6-Tetrachloro-1,4-benzenedicarboxilic acid dimethyl ester, 2,3,5,6-Tetrachloro-1,4-benzenedicarboxylic acid dimethyl ester, 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylic acid dimethyl ester, 65862-98-8, 87209-56-1

ID: 55

InChIKey: NRFJZTXWLKPZAV-UHFFFAOYSA-N
SMILES: CC(=O)NC1CCSC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 14520
synonyms found at PubChem are:
citiolone, 1195-16-0, 17896-21-8, Citiolase, Thioxidrene, Ahctl, Achtl, AHCT, N-Acetylhomocysteine thiolactone, Acetamide, N-(tetrahydro-2-oxo-3-thienyl)-, DL-N-Acetylhomocysteine thiolactone, 3-Acetamidotetrahydro-2-thiophenone, N-(2-Oxotetrahydrothiophen-3-yl)acetamide, N-(TETRAHYDRO-2-OXO-3-THIENYL)ACETAMIDE, N-Acetylhmocysteinethiolactone, N-Acetyl-dl-homocysteine thiolactone, BO 714, cythiolone, 2-Acetamido-4-mercaptobutyric acid gamma-thiolactone, Citiolone [INN:DCF], Citiolonum [INN-Latin], Citiolona [INN-Spanish], C6H9NO2S, N-Acetylhomocysteinthiolakton, NSC 22878, 2-Acetamido-4-mercaptobutyric acid thiolactone, alpha-Acetamido-gamma-thiobutyrolactone, N-(2-oxothiolan-3-yl)acetamide, EINECS 214-793-8, EINECS 241-841-5, N-(Tetrahydro-2-oxothienyl)acetamide, N-(TETRAHYDRO-2-OXO-3-THIENYL)-ACETAMIDE, N-Acetylhomocysteinthiolakton [German], BRN 0004338, NRFJZTXWLKPZAV-UHFFFAOYSA-N, .alpha.-Acetamido-.gamma.-thiobutyrolactone, (1)-N-(Tetrahydro-2-oxothien-3-yl)acetamide, DSSTox_CID_25888, DSSTox_RID_81202, DSSTox_GSID_45888, Citiolonum, Citiolona, Mucorex, Sitilon, N-(2-oxo-3-3,4,5-trihydrothienyl)acetamide, SR-01000872700, Reducdyn, Prestwick_1, N-Acetyl-DL-homocystein thiolacton, Citiolone (INN), NCGC00016568-01, CAS-1195-16-0, BILE SAC POWDER, Prestwick0_000644, Prestwick1_000644, Prestwick2_000644, Prestwick3_000644, bo714, 2-Thiolanone, 3-acetamido-, BSPBio_000647, 5-18-11-00320 (Beilstein Handbook Reference), n-acetylhomocysteinethiolactone, SCHEMBL364495, SPBio_002568, ACMC-209a31, BPBio1_000713, CHEMBL2104457, DTXSID0045888, CHEBI:94403, CTK8A9399, KS-00000ZKF, N-(2-oxo-3-thiolanyl)acetamide, dl-N-Acetylhomocysteinethiolactone, MolPort-000-395-703, HMS1570A09, HMS2097A09, HMS3714A09, Pharmakon1600-01503205, N-Acetyl-DL-homocysteinethiolactone, AC1L2406, HY-B0931, KS-000016BQ, N-Acetyl-DL-homocystein Thiolactone, NSC22878, Tox21_111388, Tox21_113346, ANW-17339, NSC-22878, NSC758402, s4558, SBB056942, AKOS002808092, AKOS016162043, Tox21_113346_1, CCG-213865, FCH1113174, MCULE-3189072897, NSC-758402, VC31147, VZ23451, ACM17896218, N-(2-Oxotetrahydro-3-thienyl)acetamide, NCGC00179491-01, NCGC00179491-04, AK122075, AN-48828, AS-11951, DL-N-Acetylhomocysteine thiolactone, 98%, LS-10265, n-(tetrahydro-2-oxo-3-thienyl)-acetamid, SC-75542, SBI-0207034.P001, 2-acetamido-4-mercaptobutyricacidthiolactone, AX8126584, DL-3-(Acetylamino)tetrahydro-2-thiophenone, TC-106084, FT-0637623, ST24031306, ST50989901, D07105, K-5482, 2-Acetamido-4-mercaptobutyric acid $g-thiolactone, C-03925, 2-Acetamido-4-mercaptobutyric acid beta-thiolactone, 2-Acetamido-4-mercaptobutyric acid I(3)-thiolactone, I04-0035, J-011416, SR-01000872700-1, SR-01000872700-2, BRD-A57957888-001-01-5, BRD-A57957888-001-06-4, I14-11945, 2-Acetamide-4-mercaptobutyric acid .gamma.-thiolactone, 2-Acetamido-4-mercaptobutyric acid .gamma.-thiolactone, 2-ACETAMIDO-4-MERCAPTOBUTYRIC ACID G-THIOLACTONE, 34148-12-4

ID: 56

InChIKey: OARGPFMFRLLKPF-UHFFFAOYSA-N
SMILES: CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 73332
synonyms found at PubChem are:
H-7 dihydrochloride, H-7, Dihydrochloride, 108930-17-2, 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride, 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride, CHEBI:82739, IN1302, 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, 2HCl, 1-(5-ISOQUINOLINE-SULFONYL)-2-METHYLPIPERAZINE, 5-(2-methylpiperazin-1-ylsulfonyl)isoquinoline dihydrochloride, Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride, SR-01000000121, 1-(5-isoquinolylsulfonyl)-2-methylpiperazine, chloride, chloride, 1-(5-Isoquinolinesulfonyl)-2-methyl-piperazine dihydrochloride, AC1Q6UWH, AC1L2JO7, BMK1-B4, CHEMBL540848, SCHEMBL1064436, CTK5F2403, MolPort-003-983-768, to_000064, Tox21_500682, BS0093, MFCD00036961, Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, dihydrochloride, SBB027327, AKOS024458555, CCG-221986, LP00682, H-7 dihydrochloride, >=98% (HPLC), NCGC00094040-01, NCGC00261367-01, RT-013180, EU-0100598, EU-0100682, H-121, ST50826284, I 7016, Isoquinoline,5-[(2-methyl-1-piperazinyl)sulfonyl]-, J-002210, SR-01000000121-2, SR-01000000121-3, SR-01000000121-6, 1-(5-isoquinolinesulfonyl)-2-methylpiperazine hydrochloride, 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline dihydrochloride, (-)-1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Di-HCl salt, 5-[(2-methylpiperazin-1-yl)sulfonyl]isoquinoline dihydrochloride, 5-[(2-methylpiperazin-4-ium-1-yl)sulfonyl]isoquinolinium dichloride, (+/-)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride

ID: 57

InChIKey: ODLCLZLDYDHRGT-NEGPAABLSA-N
SMILES: CC(=O)O[C@@H]1C[C@@H]2[C@@]([C@@H]3[C@@]1([C@]45[C@H](O4)C(=O)O[C@H]([C@@]5(CC3)C)C6=COC=C6)C)([C@H](C[C@H](C2(C)C)OC(=O)C)OC(=O)C)C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 21596331
synonyms found at PubChem are:
Khivorin, 2524-38-1, D-Homo-24-nor-17-oxachola-20,22-dien-16-one, 1,3,7-tris(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (1a,3alpha,5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-, SCHEMBL598261, CHEMBL1075850, DTXSID70179898, 1,3,7-Tris(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-D-homo-24-nor-17-oxachola-20,22-dien-16-one (1a,3alpha,5alpha,7alpha,13alpha,14beta,15beta,17aalpha)-

ID: 58

InChIKey: OENHQHLEOONYIE-JLTXGRSLSA-N
SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(CCCC2(C)C)C)\C)\C)/C)/C

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5280489
synonyms found at PubChem are:
beta-carotene, 7235-40-7, beta Carotene, beta,beta-Carotene, Betacarotene, Provitamin A, Solatene, Carotaben, Provatene, all-trans-beta-Carotene, Serlabo, Natural Yellow 26, Karotin, KPMK, C.I. Food Orange 5, Solatene (caps), Karotin [Czech], Food orange 5, Zlut prirodni 26, Betacarotenum [Latin], Betacaroteno [Spanish], Lucaratin, BetaVit, beta-Carotin, beta-Karotin, beta;-Carotene, .beta. Carotene, .beta.-Carotene, beta-Carotene, all-trans-, Betacarotenum [INN-Latin], C.I. 75130, Betacaroteno [INN-Spanish], Zlut prirodni 26 [Czech], UNII-01YAE03M7J, NSC 62794, CCRIS 3245, HSDB 3264, Diet,beta-carotene supplementation, E160A, EINECS 230-636-6, all-trans-.beta.-Carotene, CI 40800, CI 75130, MLS001066383, .beta.,.beta.-Carotene, 01YAE03M7J, CHEBI:17579, OENHQHLEOONYIE-JLTXGRSLSA-N, NSC62794, Betacarotene (INN), Betacarotene [INN], (all-E)-1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene), 1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene), (all E)-, 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene, NCGC00096081-01, SMR000112037, 116-32-5, 2,2'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(1,3,3-trimethylcyclohex-1-ene), Cyclohexene, 1,1'-(3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethyl-, (all-E)-, .beta.-Carotene, all-trans-, b-Carotene, Provitamin A1, Betacaroteno, Betacarotenum, Vetoron, trans-B-Carotene, 1,1'-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl]bis(2,6,6-trimethylcyclohexene), trans-beta-Carotene, beta carotene [USAN], SR-01000763803, Beta carotene [USAN:USP], Solate, beta-Carotine, beta -carotene, Carotene, .beta., Solatene (TN), Cyclohexene, 1,1'-(3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6,6-trimethyl-, (all-E)-, I(2)-Carotene, Beta Carotene Natural, beta Carotene (USP), trans-.beta.-Carotene, Carotene, Provitamin A, all trans beta-Carotene, all-E-.beta.-Carotene, AC1NQX3D, DSSTox_CID_253, Spectrum5_000505, .beta., .beta.-Carotene, bmse000832, D0MY8N, EC 230-636-6, AC1Q28DI, (9Z,13Z)-beta-Carotene, CHEMBL1293, DSSTox_RID_75466, BIDD:PXR0110, DSSTox_GSID_20253, BSPBio_003404, DTXSID3020253, BDBM54988, cid_5280489, HMS501A12, .beta.,.beta.-Carotene, neo B, MolPort-001-785-959, HMS2091M17, Pharmakon1600-01500143, ZINC6845076, beta-Carotene, >=97.0% (UV), Tox21_111557, C39H54, CC0205, CCG-36062, LMPR01070001, NSC755910, s1767, AKOS015896682, AC-1869, DB06755, LS-1621, NSC-755910, SDCCGMLS-0066579.P001, IDI1_000330, NCGC00096081-02, 31797-85-0, AN-14537, AS-13354, BC208855, H982, SC-19470, ST097774, CAS-7235-40-7, SBI-0051295.P003, AB2000280, N1547, 3046-EP2298772A1, 3046-EP2308839A1, C02094, D03101, J10299, AB00051925_06, AB00051925_07, beta-Carotene, Vetec(TM) reagent grade, >=93%, 117179-EP2292227A2, 117179-EP2298776A1, C-23129, I06-2213, Q-200706, SR-01000763803-2, SR-01000763803-3, SR-01000763803-4, I14-38736, beta-Carotene, Type I, synthetic, >=93% (UV), powder, UNII-N53I4V2IA6 component OENHQHLEOONYIE-JLTXGRSLSA-N, 89648336-F9B2-44A0-9BF8-62E73369CB9B, Beta Carotene, United States Pharmacopeia (USP) Reference Standard, beta-Carotene, Type II, synthetic, >=95% (HPLC), crystalline, 3,7,12,16-tetramethyl-1,18-bis-(2,2,6-trimethyl-cyclohexyl)-octadecane, beta-Carotene, Pharmaceutical Secondary Standard; Certified Reference Material, (1E,3E,5E,7E,9E,11E,13E,15E,17E)-1,18-bis(2,6,6-trimethylcyclohex-1-enyl)-3,7, 12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene, (all-E)-1,1'-(3,7,12,16-Tetramethyl-1,3,5, 7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6, 6-trimethylcyclohexene], 1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethylcyclohexene, 1,18-Bis(2,6,6-trimethyl-1-cyclohexenyl)-3,7,12,16-tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonene

ID: 59

InChIKey: OLOOJGVNMBJLLR-UHFFFAOYSA-N
SMILES: CC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"H Yang" "S Lin" "TH Ma" "LN Xu" "X Liu" "SG Hou" "WL Na"

CID is 10212
synonyms found at PubChem are:
IMPERATORIN, 482-44-0, Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen, 8-Isopentenyloxypsoralene, Marmelide, NSC 402949, CCRIS 4346, UNII-K713N25C78, 9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one, HSDB 3497, EINECS 207-581-1, 9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one, AI3-61725, CHEBI:5885, CHEMBL453805, OLOOJGVNMBJLLR-UHFFFAOYSA-N, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-, 9-(3-Methylbut-2-enyloxy)furo[3,2-g]chromen-7-one, K713N25C78, 9-(3-Methylbut-2-enyloxy)-7H-furo(3,2-g)chromen-7-one, NCGC00095209-01, 9-((3-Methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one, 9-[(3-methylbut-2-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one, 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-, 6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone, 9-[(3-METHYL-2-BUTEN-1-YL)OXY]-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE, 5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, delta-lactone, DSSTox_CID_28663, DSSTox_RID_82933, DSSTox_GSID_48737, Q-100532, 9-(3-methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one, 9-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one, 9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]-1-benzopyran-7-one, CAS-482-44-0, Pentosalen [BAN], Enoxypsoralen, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-, Pentasalen, BAN, Imperatorin,(S), 8-Prenyloxypsoralen, Spectrum_000755, 8-isopentenyloxypsoralen, 5-hydroxy-8-(1,1-dimethylallyl)psoralen, SpecPlus_000755, AC1L1UPZ, Spectrum2_000376, Spectrum3_000145, Spectrum4_001422, Spectrum5_000244, [3,2-g]chromen-7-one, D09ROW, Oprea1_407817, SCHEMBL50437, BSPBio_001850, KBioGR_001864, KBioSS_001235, SPECTRUM102076, MLS000574838, DivK1c_006851, SPBio_000531, Marmelosin, analytical standard, MEGxp0_000089, ZINC1904, DTXSID8048737, ACon1_001117, CTK5J8942, KBio1_001795, KBio2_001235, KBio2_003803, KBio2_006371, KBio3_001050, MolPort-000-881-264, HMS1922N22, HMS2218G08, HMS3261C08, HMS3354E04, BCP28280, HY-N0285, 8-(3-Methyl-2-butenyloxy)psoralen, Tox21_113179, Tox21_500413, BDBM50308719, CCG-38649, CI0030, MFCD00016881, NSC402949, 9-(3-methylbut-2-enyloxy)-7H-furo, AKOS000277029, Tox21_113179_1, AC-8046, AN-8400, API0002987, CS-5800, Imperatorin, >=98% (HPLC), powder, LP00413, MCULE-3248623364, NSC-402949, SDCCGMLS-0066373.P001, NCGC00095209-02, NCGC00095209-03, NCGC00095209-04, NCGC00095209-05, NCGC00095209-06, NCGC00169661-01, NCGC00169661-02, NCGC00261098-01, CC-29497, LS-70737, SC-16643, SMR000156241, ZB000436, TR-036857, WLN: T C566 DO LVOTJ BO2UY1&1, FT-0603414, I0904, N1859, ST45000841, W1274, 7H-Furo[3, 9-[(3-methyl-2-butenyl)oxy]-, C09269, 482I440, A827504, C-16983, SR-01000721772, I06-0320, SR-01000721772-2, 9-(3-Methyl-2-butenyloxy)-7-oxofuro[3,2-g]chromene, 9-(3-methylbut-2-enyloxy)furano[3,2-g]chromen-2-one, 9-(3-methylbut-2-enoxy)-7-furo[3,2-g][1]benzopyranone, Imperatorin, European Pharmacopoeia (EP) Reference Standard, 9-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one #, 9-[(3-methylbut-2-en-1-yl)oxy]-2H-furo[3,2-g]chromen-2-one, 9-[(3-Methylbut-2-enyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, (9-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one), 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one,9-[(3-methyl-2-buten-1-yl)oxy]-, 9-[(3-Methyl-2-butenyl)-oxy]-7H-furo[3,2-g][1][benzopyran-7-one, 9-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 9CI, 5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, .delta.-lactone, 70102-00-0, InChI=1/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H

ID: 60

InChIKey: OPYKHUMNFAMIBL-UHFFFAOYSA-L
SMILES: C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4)(C)C)O)O)C.[Br-].[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9399
synonyms found at PubChem are:
Hemicholinium-3, Hemicholinium bromide, 312-45-8, HEMICHOLINIUM 3, Hemicholine, Hemicholinium dibromide, Hemicholinium-3 bromide, Hemicholinium 3 dibromide, Hemicholinium-3 dibromide, [3H]hemicholinium-3, [3H]-hemicholinium-3, EINECS 206-227-3, HC-3, NSC 527583, [3H]HC-3, [3H]-HC-3, Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-, dibromide, 2,2'-(4,4'-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium) dibromide, Morpholinium, 2,2'-(4,4'-biphenylylene)bis(2-hydroxy-4,4-dimethyl-, dibromide, Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, dibromide, SR-01000075620, Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-, bromide (1:2), Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, bromide (1:2), Prestwick_566, AC1L1SYD, D05AFI, SCHEMBL564623, CHEMBL197027, GTPL4493, C24H34N2O4.2Br, MolPort-003-941-587, HMS1569O07, HMS2096O07, HMS3261D18, HMS3713O07, Tox21_500578, 2461AH, ACM312458, MFCD00011978, AKOS026750387, CCG-220393, CCG-221882, LP00578, NCGC00093959-01, NCGC00261263-01, LS-93529, Hemicholinium-3, solid, >=95% (HPLC), EU-0100578, FT-0741707, H-108, C-45763, J-018290, SR-01000075620-1, SR-01000075620-5, 2,2'-(4,4'-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium bromide), 2,2'-(1,1'-Biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-morpholinium) dibromide, 2,2'-(1,1'-Biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-morpholinium) dibromide (9CI), 2,2'-(biphenyl-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) bromide, 2,2 inverted exclamation marka-(4,4 inverted exclamation marka-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium bromide), 2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol dibromide, 2-hydroxy-2-{4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl}-4,4-dimethylmorpholin-4-ium dibromide

ID: 61

InChIKey: PFTAWBLQPZVEMU-DZGCQCFKSA-N
SMILES: C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O

biological descriptors:

CFTR relevance: no effect

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"H Yang" "Y Zhang" "T Ma" "L Zhu" "X Gao" "B Yu" "L Chen"

CID is 9064
synonyms found at PubChem are:
(+)-catechin, CATECHIN, Cianidanol, 154-23-4, Catechuic acid, Cyanidanol, Catechinic acid, D-Catechin, Catergen, Cianidol, (+)-Cyanidanol, (+)-Catechol, (+)-Cyanidan-3-ol, Biocatechin, D-(+)-Catechin, Catechin (flavan), Catechol (flavan), Dexcyanidanol, D-Catechol, (+)-Catechin Hydrate, (2R,3S)-Catechin, 3-Cyanidanol, (+)-, (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol, Cianidanolum, Catechu, Gambier, Transepar, Katha, (+)-Cyanidanol-3, (2R,3S)-(+)-Catechin, (+)-Cianidanol, Cutch (dye), 3,3',4',5,7-Flavanpentol, KB-53, CCRIS 6855, (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol, Cianidanol [INN:JAN], C.I. Natural Brown 3, Cianidanolum [INN-Latin], NSC 2819, UNII-8R1V1STN48, Catechol (+), 2,3-trans-catechin, 2,3-Dihydro-4-desoxoquercetin, CHEBI:15600, AI3-22757, NSC2819, (+)-(2R,3S)-5,7,3',4'-Tetrahydroxyflavan-3-ol, CATECHIN, D, (2R,3S)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol, 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-trans)-, EINECS 205-825-1, Catechin-(+,-) hydrate, 7295-85-4, (2R,3S)-3,3',4',5,7-Flavanpentol, 8R1V1STN48, CHEMBL311498, PFTAWBLQPZVEMU-DZGCQCFKSA-N, NSC-2819, (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, 2H-1-benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S)-, C15H14O6, trans-(+)-3,3',4',5,7-Flavanpentol, Zyma, Cyanidanol-3, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, (+)-Cyanidol-3, (+)-(2R:3S)-5,7,3',4'-Tetrahydroxyflavan-3-ol, (3S,2R)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol, (+/-)-Catechin hydrate, Epicatechin-(-), dl-Catechol, (-)-Catechol, MLS001056745, Catechine dl-form, (+/-)-Catechin, 321-01-7, (+-)-catechin, KB 53, SR-01000075742, SMR000326724, Catechinate, Catechuate, Ent-Catechin, Z 7300, Procyanidin polymer, Teafuran 30A, KXN, Prestwick_998, Sunkatol No. 1, EINECS 230-731-2, (+)-catechinhydrate, Spectrum_000395, (+)-Catechin,(S), 2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol #, Prestwick0_000642, Prestwick0_000817, Prestwick1_000642, Prestwick1_000817, Prestwick2_000642, Prestwick2_000817, Prestwick3_000642, Spectrum2_000167, Spectrum3_000242, Spectrum4_001763, Spectrum5_000345, Epitope ID:116872, AC1L1S8M, Lopac0_000219, SCHEMBL19741, BSPBio_000643, BSPBio_001624, KBioGR_002245, KBioSS_000875, BIDD:ER0378, DivK1c_000647, ( )-2-(3,4-Dihydroxyphenyl)-3,5,7-chromantriol, (+)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromantriol, (-)-trans-3,3',4',5,7-Pentahydroxyflavane, SPBio_000033, SPBio_002564, SPBio_002634, BPBio1_000709, cid_107957, DTXSID3022322, ACon1_001489, BDBM23416, BDBM60836, HMS502A09, KBio1_000647, KBio2_000875, KBio2_003443, KBio2_006011, KBio3_001124, KS-00000ZEC, 3,3',4',5,7 Cflavanpentol, YK-85 Light Yellow Powder 85, 4c94, MolPort-001-740-277, NINDS_000647, HMS1570A05, HMS1570D15, HMS2097A05, HMS3260L19, Pharmakon1600-00210205, ZINC119983, (+)-Catechin, analytical standard, HY-N0898, TNP00270, Tox21_500219, 6282AF, ANW-46737, CCG-40007, LMPK12020001, NSC755824, s4722, Cianidanol solution, 20 mM in DMSO, trans3,3,4,5,7 pentahydroxyflavane, AKOS015960546, trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, CS-3759, LP00219, MCULE-1532117250, ND-0342, NSC-755824, SDCCGMLS-0066526.P001, IDI1_000647, NCGC00017331-01, NCGC00017331-02, NCGC00017331-03, NCGC00017331-04, NCGC00017331-05, NCGC00093689-01, NCGC00093689-02, NCGC00093689-03, NCGC00260904-01, (+)-Catechin solution, 20 mM in DMSO, 100786-01-4, AC-11608, AJ-11643, AN-44045, BC202817, LS-39923, LS-53711, NCI60_002303, SC-46023, ST057176, ZB004048, SBI-0050207.P003, AX8035583, ST2407915, TC-135482, EU-0100219, FT-0613995, ST24039239, (-)-trans-3,3',4',5,7-Pentahydroxyflavan, (2S,3R)-3,3',4',5,7-Pentahydroxyflavane, C 1251, C06562, Cianidanol, disposable screening library format, AB00051886_13, 154C234, A809512, NATURAL BROWN 3 (CUTCH EXTRA OR GAMBIER), Q-100183, SR-01000075742-1, SR-01000075742-7, SR-01000075742-8, SR-01000075742-9, BRD-K58736316-001-07-9, BRD-K58736316-001-08-7, SR-01000075742-10, SR-01000075742-12, SR-01000075742-14, D4A04A57-7609-451F-A446-53F4DFAD15F5, UNII-5J4Y243W61 component PFTAWBLQPZVEMU-DZGCQCFKSA-N, (2R,3S)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triol;hydrate, (+)-Catechin, United States Pharmacopeia (USP) Reference Standard, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1H-chromene-3,5,7-triol, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol;hydrate, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate, (2R,3S)-2-[3,4-bis(oxidanyl)phenyl]-3,4-dihydro-2H-chromene-3,5,7-triol, (2R,3S)-2-[3,4-bis(oxidanyl)phenyl]-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate, (2R-trans)-2-(3,4-Dihydroxyphenyl)-3-4-dihydro-2H-1-benzopyran-3,5,7-triol, 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, (2R-trans), 2H-1-Benzopyran-3,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-trans)-, 2H-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R,3S)-, 159761-73-6, 16198-00-8, 29907-20-8, 4211-28-3, 5323-80-8, 72690-97-2, InChI=1/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s

ID: 62

InChIKey: PSCZYIVKEHPWIP-VYRMFUMRSA-N
SMILES: CN1CCC2=C[C@H](C3C([C@H]21)C4=CC5=C(C=C4C(=O)O3)OCO5)OC.[N+](=O)(O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6419925
synonyms found at PubChem are:
ungerine nitrate, Prestwick_198, HMS1570I19, CCG-208376

ID: 63

InChIKey: PZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILES: Cc1c(cc(c(=O)[nH]1)C#N)c2ccncc2

biological descriptors:

CFTR relevance: Phosphodiesterase 3 inhibitor

Category:
Influence on CFTR function none
Order of interaction indirect
subcellular compartment several

reference list:

"KL Hamilton" "PC Chao"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4197
synonyms found at PubChem are:
milrinone, 78415-72-2, Primacor, Corotrope, Corotrop, Milrinona, Milrinonum, Milrinonum [Latin], Milrinona [Spanish], Milrila, UNII-JU9YAX04C7, YM 018, Milrila (TN), Milrinone [USAN:BAN:INN], WIN 47203-2, CCRIS 3795, 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile, Win-47203, Win-47203-2, 3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone, 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile, EINECS 278-903-6, CHEMBL189, BRN 3546821, JU9YAX04C7, C12H9N3O, 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile, CHEBI:50693, 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile, PZRHRDRVRGEVNW-UHFFFAOYSA-N, 6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile, NCGC00015675-08, NCGC00164390-01, 1,6-Dihydro-2-methyl-6-oxo-3,4-bipyridine-5-carbonitrile, 111GE027, (3,4'-Bipyridine)-5-carbonitrile, 6-dihydro-2-methyl-6-oxo-, Primacor (TN), 1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)NICOTINONITRILE, CAS-78415-72-2, M1663, (3,4'-BIPYRIDINE)-5-CARBONITRILE, 1,6-DIHYDRO-2-METHYL-6-OXO-, DSSTox_CID_3324, M 4659, DSSTox_RID_76978, DSSTox_GSID_23324, 6-Methyl-5-(4-pyridyl)-2-pyridone-3-carbonitrile, PRIMACOR IN DEXTROSE 5% IN PLASTIC CONTAINER, W-104284, MILRINONE LACTATE IN DEXTROSE 5% IN PLASTIC CONTAINER, [3,4'-Bipyridine]-5-carbonitrile, 1,6-dihydro-2-methyl-6-oxo-, 1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile, 1,6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrile, SMR000058475, SR-01000075524, Milrinone [USAN:USP:INN:BAN], Milrinone(Primacor), WIN 47203, Milrinone (Primacor), Tocris-1504, AC1L1HMP, AC1Q2EBX, Prestwick0_001065, Prestwick1_001065, Prestwick2_001065, Prestwick3_001065, Lopac-M-4659, D0Y9ZE, (non-labelled)Milrinone-d3, Milrinone (JAN/USP/INN), Lopac0_000737, SCHEMBL36947, BSPBio_001050, Milrinone (JAN/USAN/INN), MLS000028818, MLS001424052, MLS006011946, BIDD:GT0197, SPBio_002965, BPBio1_001156, GTPL5225, SCHEMBL8309385, DTXSID5023324, BDBM15296, CTK7C7151, KS-00000GSZ, AOB5617, BIM0128, MolPort-003-666-840, ZX-AFC000063, HMS1571E12, HMS2051L10, HMS2090J14, HMS2098E12, HMS2234A23, HMS3262C16, HMS3267P12, HMS3370H18, HMS3393L10, HMS3656G06, HMS3715E12, Pharmakon1600-01505489, BCP02956, ZINC9224016, Tox21_112113, Tox21_400069, Tox21_500737, ANW-42920, BG0378, CM0151, MFCD00133539, Milrinone, >=97% (TLC), powder, NSC760072, s2484, SBB055743, AKOS015836135, Tox21_112113_1, AC-4730, API0003394, BCP9000926, CCG-101020, CCG-204822, CS-1367, DB00235, KS-1440, LP00737, MCULE-8377851655, NC00270, NSC-760072, WIN-472032, NCGC00015675-01, NCGC00015675-02, NCGC00015675-03, NCGC00015675-04, NCGC00015675-05, NCGC00015675-06, NCGC00015675-07, NCGC00015675-09, NCGC00015675-11, NCGC00025189-01, NCGC00025189-02, NCGC00025189-03, NCGC00261422-01, AJ-59392, AK174563, AN-11687, BC208811, CC-30960, CPD000058475, EN002063, HY-14252, LS-44610, SAM001246611, SC-46003, SMR004703527, WIN 47,203-2, BCP0726000256, 1,6-Dihydro-2-methyl-6-oxo-(3,4&prime, AB0010910, AB1009542, AX8014448, AB00514027, EU-0100737, FT-0630859, C07224, D00417, AB00514027-02, AB00514027-03, AB00514027_04, AB00514027_05, AB00597139-08, 415M722, A839417, C-10984, I06-0259, SR-01000075524-1, SR-01000075524-3, SR-01000075524-4, SR-01000075524-6, BRD-K67080878-001-05-5, Z1522568219, 6-methyl-2-oxo-5-(4-pyridyl)-1H-pyridine-3-carbonitrile, 6-methyl-2-oxo-5-(4-pyridyl)hydropyridine-3-carbonitrile, 1,2-dihydro-6-methyl-2-oxo-5-(4 -pyridinyl)nicotinonitrile, 1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)-NICOTIN, Milrinone, United States Pharmacopeia (USP) Reference Standard, 6-methyl-2-oxidanylidene-5-pyridin-4-yl-1H-pyridine-3-carbonitrile, 2-Methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile (Milrinone)

ID: 64

InChIKey: QELUYTUMUWHWMC-UHFFFAOYSA-N
SMILES: CC1=NN(C(=O)C1)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4021
synonyms found at PubChem are:
edaravone, 89-25-8, Radicut, 1-Phenyl-3-methyl-5-pyrazolone, 3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE, Norphenazone, Developer Z, Methylphenylpyrazolone, Norantipyrine, C.I. Developer 1, MCI-186, Phenylmethylpyrazolone, 3-Methyl-1-phenyl-5-pyrazolone, Phenyl methyl pyrazolone, Radicava, 1-Phenyl-3-methyl-5-oxo-2-pyrazoline, 1-Phenyl-3-methylpyrazolone, CI Developer 1, 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-phenyl-, edarabone, 3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one, edaravone(jan), 1-Phenyl-3-methylpyrazolone-5, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, 3-Methyl-1-phenylpyrazol-5-one, 3-Methyl-1-phenyl-2-pyrazoline-5-one, NCI-C03952, 2-Pyrazolin-5-one, 3-methyl-1-phenyl-, 5-Pyrazolone, 3-methyl-1-phenyl-, 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one, 5-methyl-2-phenyl-4H-pyrazol-3-one, Monopyrazolone, NSC 12, Edaravone (MCI-186), 1-Fenyl-3-methyl-2-pyrazolin-5-on, CCRIS 512, Radicut (TN), 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one, CHEBI:31530, HSDB 4102, 1-Fenyl-3-methyl-2-pyrazolin-5-on [Czech], EINECS 201-891-0, IN1263, BRN 0609575, AI3-03557, MLS000069602, QELUYTUMUWHWMC-UHFFFAOYSA-N, NSC-2629, (MCI-186), NSC-26139, CDS1_000986, NCGC00164015-01, SMR000059020, M0687, DSSTox_CID_1130, DSSTox_RID_75961, DSSTox_GSID_21130, AE-641/00371017, 3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE (MCI-186), WLN: T5NMV DHJ BR& E1, 1-Phenyl-3-methyl-2-pyrazolin-5-on, CAS-89-25-8, Edaravone [INN], 3H-Pyrazol-3-one,4-dihydro-5-methyl-2-phenyl-, SR-01000000135, MCI 186, Radicava (TN), Radicut;MCI-186, PubChem13301, Spectrum_000267, Tocris-0786, Edaravone (JAN/INN), Edaravone [USAN:INN], AC1Q2PHG, AC1Q6EYP, Maybridge1_005738, Opera_ID_1057, Spectrum2_001574, Spectrum3_000971, Spectrum4_001091, Spectrum5_001217, Edaravone (JP17/INN), D06DLI, EC 201-891-0, AC1L1H8H, SCHEMBL4704, BSPBio_001235, BSPBio_002601, KBioGR_000575, KBioGR_001502, KBioSS_000575, KBioSS_000747, KSC448M1D, MLS001146878, MLS002415675, MLS006011753, DivK1c_001018, DivK1c_002026, SPECTRUM1503635, SPBio_001508, CHEMBL290916, DTXSID9021130, BCBcMAP01_000127, CTK3E8611, HMS503K17, HMS557M18, KBio1_001018, KBio2_000575, KBio2_000747, KBio2_003143, KBio2_003315, KBio2_005711, KBio2_005883, KBio3_001029, KBio3_001030, KBio3_001821, NSC2629, edaravone and MCI-186 and PMP, MolPort-000-182-197, NINDS_001018, BCPP000246, Bio1_000438, Bio1_000927, Bio1_001416, Bio2_000448, Bio2_000928, HMS1362M17, HMS1792M17, HMS1990M17, HMS2234M19, HMS3266F04, HMS3403M17, HMS3654L15, Pharmakon1600-01503635, ACT07289, BCP26336, HY-B0099, KS-00000X6I, NSC26139, Tox21_112077, Tox21_201747, Tox21_302819, BBL011741, BDBM50200541, CCG-39352, MFCD00003138, NSC758622, s1326, STK201315, ZINC18203737, 3-methyl-1-phenyl-2-pyrazolin-5one, AKOS000313817, Tox21_112077_1, AC-4745, BCP9000635, CS-1832, DB12243, LS-1892, MCI-186, Radicut, 89-25-8, NE10266, NSC-758622, RL05601, RTR-028045, IDI1_001018, IDI1_002203, 1-PEHNYL-3-METHYL-5-PYRAZALONE, NCGC00018218-01, NCGC00018218-02, NCGC00018218-03, NCGC00018218-04, NCGC00018218-05, NCGC00018218-06, NCGC00018218-07, NCGC00018218-08, NCGC00018218-10, NCGC00018218-17, NCGC00022665-02, NCGC00022665-04, NCGC00022665-05, NCGC00022665-06, NCGC00256515-01, NCGC00259296-01, 4CA-0486, AJ-70469, AN-11638, BC205186, SC-13582, ST012744, SBI-0051836.P002, AB2000046, DB-002517, KB-183502, ST2410773, TR-028045, AM20060748, FT-0608243, 5-methyl-2-phenyl-2,4-dihydro-3-pyrazolone, 5-methyl-2-phenyl-2,4-dihydropyrazol-3-one, 3-Methyl-1-phenyl-2-pyrazoline-5-one, 99%, 4E-901, 5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one, C13008, D01552, AB00375776_14, AB00375776_15, 2 4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one, 2,4-dihydro-2-phenyl-5-methyl-3H-pyrazol-3-one, I01-2810, Q-200386, SR-01000000135-2, SR-01000000135-3, SR-01000000135-5, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one #, BRD-K35458079-001-04-2, BRD-K35458079-001-12-5, BRD-K35458079-001-23-2, Z50145861, F0391-0021, 3-Methyl-1-phenyl-2-pyrazoline-5-one, SAJ special grade, 3-Methyl-1-phenyl-2-pyrazoline-5-one, purum, >=98.0% (NT), 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (Edaravone), Phenazone impurity A, European Pharmacopoeia (EP) Reference Standard, Antipyrine Related Compound A, United States Pharmacopeia (USP) Reference Standard, InChI=1/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H, 115566-83-1, 12235-58-4, 206195-95-1, 52224-17-6, 62495-97-0, 72134-66-8

ID: 65

InChIKey: QGXBDMJGAMFCBF-LUJOEAJASA-N
SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441302
synonyms found at PubChem are:
EPIANDROSTERONE, 481-29-8, trans-Androsterone, Isoandrosterone, 3Beta-hydroxy-5alpha-androstan-17-one, 3beta-Hydroxyetioallocholan-17-one, epi-andosterone, 5alpha-Androstan-3beta-ol-17-one, iso-Androsterone, d-Epiandrosterone, UNII-8TR252Z538, 3-Epiandrosterone, (3beta,5alpha)-3-hydroxyandrostan-17-one, CHEMBL272195, 3beta-Hydroxy-androstan-17-one, CHEBI:541975, QGXBDMJGAMFCBF-LUJOEAJASA-N, Androsterone, epi-, MFCD00064134, NSC 93996, 8TR252Z538, ST072176, Androstan-17-one, 3-hydroxy-, (3b,5a)-, epi-Androsterone, C19H30O2, (1S,2S,5S,7S,11S,15S,10R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11, 15>]heptadecan-14-one, SMR000718744, Androsterone, (3beta)-, AOX, Prestwick_699, EINECS 207-563-3, 3-beta-Hydroxy-5-alpha-androstan-17-one, AC1L9AXM, Prestwick0_000440, Prestwick1_000440, Prestwick2_000440, Prestwick3_000440, EC 207-563-3, BSPBio_000460, MLS000563092, MLS001304190, MLS001333976, MLS001333977, MLS002153812, SCHEMBL295167, SPBio_002399, BPBio1_000506, MolPort-002-506-907, HMS1569G22, HMS2096G22, HMS2235I04, HMS3713G22, ACT02601, Epiandrosterone (3|A-androsterone), HY-I0352, ZINC3861661, BBL030012, BDBM50236240, LMST02020023, s2832, SBB012505, STK801866, AKOS001582886, CCG-220440, CHM0029415, CS-5183, EBD2157888, NCGC00142619-02, NCGC00142619-04, AC-16141, AS-13045, CC-27483, H110, KB-50541, SC-16224, (3beta, 5alpha)-androstan-3-ol- 17-one, Androstan-17-one,3-hydroxy-, (3b,5a)-, TL8003251, E0374, C07635, J10456, M-1324, 5alpha-Androstan-17-one, 3beta-hydroxy- (8CI), C-18233, SR-01000837513, SR-01000837513-2, W-106055, Androstan-17-one, 3-hydroxy-, (3beta,5alpha)- (9CI), (3S,5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

ID: 66

InChIKey: QIVBCDIJIAJPQS-VIFPVBQESA-N
SMILES: C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6305
synonyms found at PubChem are:
L-tryptophan, tryptophan, 73-22-3, L-Tryptophane, (S)-Tryptophan, Tryptophane, h-Trp-oh, Optimax, trofan, tryptacin, Ardeytropin, Pacitron, Indole-3-alanine, Kalma, L-beta-3-Indolylalanine, (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid, L-Tryptofan, L-Trp, L-(-)-Tryptophan, 3-Indol-3-ylalanine, Tryptophan (VAN), 1-beta-3-Indolylalanine, Tryptophan (H-3), Triptofano [Spanish], Tryptophanum [Latin], 1H-Indole-3-alanine, 1beta-3-Indolylalanine, 2-Amino-3-indolylpropanoic acid, triptofano, Tryptophanum, Lyphan, Tryptan, (S)-alpha-Amino-1H-indole-3-propanoic acid, Tryptophane [French], (L)-TRYPTOPHAN, (-)-Tryptophan, alpha'-Amino-3-indolepropionic acid, Tryptophan [USAN:INN], L-alpha-amino-3-indolepropionic acid, L-alpha-Aminoindole-3-propionic acid, Sedanoct, (S)-alpha-Aminoindole-3-propionic acid, 1H-Indole-3-alanine (VAN), EH 121, Tryptophan, L-, trp, L(-)-Tryptophan, Alanine, 3-indol-3-yl-, CCRIS 617, l-b-3-Indolylalanine, L-Alanine, 3-(1H-indol-3-yl)-, 1H-Indole-3-alanine, (S)-, alpha-Amino-3-indolepropionic acid, L-, Alti-Tryptophan, HSDB 4142, (S)-alpha-amino-beta-(3-indolyl)-propionic acid, NCI-C01729, AI3-18478, UNII-8DUH1N11BX, L-Ttp, Indole-3-propionic acid, alpha-amino-, 1H-Indole-3-propanoic acid, alpha-amino-, (S)-, L-(-)-Tryptophane, Propionic acid, 2-amino-3-indol-3-yl-, CHEBI:16828, L-Tryptophan (9CI), (S)-2-Amino-3-(3-indolyl)propionic acid, Tryptophan (USP/INN), (S)-(-)-Tryptophan, (S)-a-Amino-b-indolepropionic acid, (S)-a-Aminoindole-3-propionic acid, Alanine, 3-indol-3-yl, EINECS 200-795-6, Lopac-T-0254, NSC 13119, (S)-(-)-Tryptopha n, 8DUH1N11BX, (S)-a-Amino-1H-indole-3-propanoic acid, (S)-alpha-Amino-beta-indolepropionic acid, CHEMBL54976, TRP-01, L-TRYPTOPHAN SIGMA GRADE, alpha-Amino-beta-(3-indolyl)-propionic acid, l-a-Aminoindole-3-propionic acid, (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid, 2-amino-3-indol-3-ylpropionic acid, Propionic acid, 2-amino-3-indol-3-yl, 2-Amino-3-(lH-indol-3-yl)-propanoic acid, S(-)-1-alpha-Aminoindole-3-propionic acid, DSSTox_CID_1419, alpha-amino-beta-(3-indolyl)-pr opionic acid, T 0254, DSSTox_RID_76152, (S)-(-)-2-Amino-3-(3-indolyl)propionic Acid, DSSTox_GSID_21419, L-Trytophane, 151A3008-4CFE-40C9-AC0B-467EF0CB50EA, D-Trp-OH, CAS-73-22-3, 80206-30-0, trytophan, alpha-Amino-3-Indoleproprionic Acid, L-Trytophan, 1qaw, L-Tryptophan premix, L-Tryptophan,(S), L-Trp-OH, PubChem10984, 2a4m, L-Tryptophan (JP15), L-Tryptophan (JP17), Tryptophan, L-(8CI), TRP NH3+ COOH, Tryptophan (L-Tryptophan), Tryptophan, L- (8CI), bmse000050, bmse000868, bmse001017, D05EJG, Epitope ID:136043, EC 200-795-6, AC1L1M8F, SCHEMBL7328, 2-Amino-3-indolylpropanoate, (S)-1H-Indole-3-alanine, Lopac0_001183, GTPL717, KSC377I3D, MLS001056750, DivK1c_000457, (s)-a-amino-b-indolepropionate, AC1Q4U80, DTXSID5021419, (S)-a-Aminoindole-3-propionate, BDBM21974, CTK2H7431, HMS501G19, KBio1_000457, ZINC83315, BIT0720, 3-(1H-indol-3-yl)-L-Alanine, MolPort-001-794-499, MolPort-044-812-611, NINDS_000457, QIVBCDIJIAJPQS-VIFPVBQESA-N, ZX-AFC000605, alpha-Aminoindole-3-propionic acid, D-2-Amino-3-indolepropionic acid, HMS3263N07, L-2-Amino-3-indolepropionic acid, Pharmakon1600-01500600, ACT08662, STR02722, ZX-AT022248, (S)-alpha-Aminoindole-3-propionate, Tox21_201246, Tox21_300359, Tox21_501183, ANW-36308, GM0674, HTS001390, MFCD00064340, NSC757373, (s)-alpha-amino-beta-indolepropionate, L-Tryptophan, Vetec(TM), 98.5%, (S)-a-Amino-1H-indole-3-propanoate, AKOS015854052, Indoe-3-propionic acid, alpha-amino-, AM82273, AN-8742, CCG-205257, CS-W020011, DB00150, LP01183, LS-1622, MCULE-8004234494, NSC-757373, OR28930, RP26086, RTC-066620, IDI1_000457, NCGC00015994-01, NCGC00094437-01, NCGC00094437-02, NCGC00094437-03, NCGC00094437-04, NCGC00254424-01, NCGC00258798-01, NCGC00261868-01, (S)-alpha-Amino-1H-indole-3-propanoate, AC-17050, AJ-10635, AK-50074, BP-13286, BR-50074, KB-53414, SMR000326686, AB1007074, AX8034769, DB-029986, L-Tryptophan, BioUltra, >=99.5% (NT), LS-185087, ST2419449, TC-066620, A7403, EU-0101183, FT-0627592, (S)-Tryptophan 1H-Indole-3-alanine, (S)-, 73T223, C00078, D00020, L-Tryptophan, reagent grade, >=98% (HPLC), M02943, AB00373874_05, L-Tryptophan, Vetec(TM) reagent grade, >=98%, (S)-2-amino-3-(1H-Indol-3-yl)-propionic acid, C-48302, SR-01000075590, SR-01000075590-1, F0001-2364, Z1245635763, L-Tryptophan, certified reference material, TraceCERT(R), Tryptophan, European Pharmacopoeia (EP) Reference Standard, UNII-N7U7BXP2OI component QIVBCDIJIAJPQS-VIFPVBQESA-N, UNII-X9U7434L7A component QIVBCDIJIAJPQS-VIFPVBQESA-N, L-Tryptophan, United States Pharmacopeia (USP) Reference Standard, (S)-2-Amino-3-(3-indolyl)propionic acid; L-|A-Amino-3-indolepropionic acid, 154635-35-5, L-Tryptophan, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%, L-Tryptophan, PharmaGrade, Ajinomoto, EP, JP, USP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture, (2S)-2-azaniumyl-3-(1H-indol-3-yl)propanoate, (2S)-2-ammonio-3-(1H-indol-3-yl)propanoate, 3rzi, L-tryptophan zwitterion, 3f3a, 3qs4, 3qs5, 3qs6, AC1OCMF3, 2-amino-3-indolylpropanic acid, CHEBI:57912, CJ-00673, A837752

ID: 67

InChIKey: QONLGXRPRAIDGI-UHFFFAOYSA-N
SMILES: CC(C)NCC(C1=CC2=CC=CC=C2C=C1)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 60975
synonyms found at PubChem are:
PRONETHALOL HYDROCHLORIDE, Pronetalol hydrochloride, 51-02-5, 2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride, Alderlin hydrochloride, Nethalide hydrochloride, Pronethalol.HCl, DL-Pronethalol hydrochloride, CCRIS 534, Naphthylisoproterenol hydrochloride, ICI 38174, AY 6204, CHEBI:82525, alpha-((Isopropylamino)methyl)-2-naphthalenemethanol hydrochloride, alpha-(((1-Methylethyl)amino)methyl)-2-naphthalenemethanol, hydrochloride, 2-[(1-methylethyl)amino]-1-naphthalen-2-ylethanol hydrochloride, Pronetalol HCl, Naphthalenemethanol, alpha-((isopropylamino)methyl)-, hydrochloride, SR-01000597857, AC1L1U9R, PRONETALOLHYDROCHLORIDE, MLS002154081, SPECTRUM1503628, SCHEMBL3203560, CHEMBL1876082, DTXSID3021194, CTK8I9459, MolPort-003-666-490, HMS1571C09, HMS1922G06, Pharmakon1600-01503628, ACM51025, CCG-39348, ICI-38174, NSC758482, 2-Naphthalenemethanol, .alpha.-[[(1-methylethyl)amino]methyl]-, hydrochloride, AKOS024458662, LS-7673, NSC-758482, NCGC00095061-01, NCGC00095061-02, CC-11092, SMR001233390, DB-051883, FT-0631217, C19513, C-16638, SR-01000597857-1, SR-01000597857-3, SR-01000597857-4, 2-(isopropylamino)-1-(2-naphthyl)ethanol hydrochloride, 1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol hydrochloride, 1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol;hydrochloride, 2-(Isopropylamino)-1-(naphthalen-2-yl)ethanol hydrochloride, 2-(isopropylamino)-1-(naphthalen-2-yl)ethan-1-ol hydrochloride, 2-Naphthalenemethanol, alpha-(((1-methylethyl)amino)methyl)-, hydrochloride, 325-16-6, 6426-40-0, SCHEMBL14973465

ID: 68

InChIKey: RGSUZUQISVAJJF-UHFFFAOYSA-N
SMILES: COC1=CC(=O)C(=CC1=O)C(C=C)c2ccccc2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 99926
synonyms found at PubChem are:
4-Methoxydalbergione, 28396-75-0, NSC269121, NSC629750, 2-Methoxy-5-(1-phenylallyl)-4-benzoquinone, 2-Methoxy-5-(1-phenylallyl)-p-benzoquinone, NSC 269121, Spectrum_001081, SpecPlus_000079, Spectrum2_000654, Spectrum3_000201, Spectrum4_000941, Spectrum5_001903, BSPBio_001781, KBioGR_001522, KBioSS_001561, SPECTRUM201092, DivK1c_006175, SPBio_000687, AC1L418P, CHEMBL1554531, KBio1_001119, KBio2_001561, KBio2_004129, KBio2_006697, KBio3_001281, CCG-38560, NSC-269121, NSC-629750, SDCCGMLS-0066445.P001, NCGC00095497-01, NCGC00095497-02, NCI60_002183, 2-methoxy-5-(1-phenylallyl)-1,4-benzoquinone, SR-05000002505, SR-05000002505-1, 2-Methoxy-5-(1-phenyl-2-propenyl)benzo-1,4-quinone, 2-methoxy-5-(1-phenylallyl)cyclohexa-2,5-diene-1,4-dione, 2,5-Cyclohexadiene-1,4-dione, 2-methoxy-5-(1-phenyl-2-propenyl)-, 2-methoxy-5-(1-phenylprop-2-enyl)cyclohexa-2,5-diene-1,4-dione

ID: 69

InChIKey: RODXRVNMMDRFIK-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C=CC(=O)O2)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"H Yang" "S Lin" "TH Ma" "LN Xu" "X Liu" "SG Hou" "WL Na"

CID is 5280460
synonyms found at PubChem are:
scopoletin, 92-61-5, Gelseminic acid, 6-Methylesculetin, 7-Hydroxy-6-methoxy-2H-chromen-2-one, Chrysatropic acid, Scopoletine, 7-Hydroxy-6-methoxycoumarin, Murrayetin, Scopoletol, 6-O-Methylesculetin, Escopoletin, 6-Methoxy-7-hydroxycoumarin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, 6-Methoxyumbelliferone, 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-, Esculetin 6-methyl ether, beta-Methylesculetin, Esculetin-6-methyl ether, .beta.-Methylesculetin, Buxuletin, UNII-KLF1HS0SXJ, COUMARIN, 7-HYDROXY-6-METHOXY-, 7-hydroxy-6-methoxychromen-2-one, 7-Hydroxy-5-methoxycoumarin, NSC 405647, CCRIS 3592, KLF1HS0SXJ, EINECS 202-171-9, NSC405647, BRN 0156296, CHEMBL71851, CHEBI:17488, RODXRVNMMDRFIK-UHFFFAOYSA-N, 7-hydroxy-6-methoxy-chromen-2-one, TNP00096, NSC-405647, S-2000, 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy- (9CI), Chrysotropic Acid, Acid, Gelseminic, Scopoletin solution, 100 mM in DMSO, Acid, Chrysotropic, SMR000112541, 92-61-5 solution, 100 mM in DMSO, Gelseminic acid solution, 100 mM in DMSO, 6-Methylesculetin solution, 100 mM in DMSO, SR-01000841273, Baogongteng B, b-Methylaesculetin, beta -methylesculetin, PubChem15777, Scopoletin, >=99%, Prestwick0_000962, Prestwick1_000962, Prestwick2_000962, Prestwick3_000962, Spectrum2_001207, Spectrum3_001532, Spectrum4_001054, Spectrum5_000654, Aesculetin 6-methyl ether, D05QOR, AC1NQX27, BIDD:PXR0125, BSPBio_000963, BSPBio_002944, KBioGR_001348, 5-18-03-00203 (Beilstein Handbook Reference), 7-hydroxy-6-methoxy-coumarin, MLS002154074, MLS002472878, DivK1c_000720, SCHEMBL147702, SPECTRUM1502242, 7-hydroxy 6-methoxy coumarine, SPBio_000994, SPBio_002884, Scopoletin, analytical standard, BPBio1_001061, MEGxp0_001192, DTXSID0075368, ACon1_000143, HMS502D22, KBio1_000720, KBio3_002444, KS-00000YGS, ZINC57733, BIS1402, MolPort-000-707-493, NINDS_000720, ZX-AFC000681, HMS1571A05, HMS1921N16, HMS2098A05, HMS2268G04, ALBB-023369, BCP13342, HY-N0342, ZX-AN021883, ZX-AT021192, 6-methoxy-7-oxidanyl-chromen-2-one, BDBM50156693, CCG-39140, MFCD00006872, TD8126, Scopoletin solution, 20 mM in DMSO, AKOS000277133, CS-5791, FCH1115349, MCULE-6077230919, OR22352, RTR-029034, CAS-92-61-5, IDI1_000720, 7-hydroxy-6-methoxy-1-benzopyran-2-one, 92-61-5 solution, 20 mM in DMSO, NCGC00016349-01, NCGC00016349-02, NCGC00016349-03, NCGC00016349-04, NCGC00016349-05, NCGC00016349-06, NCGC00016349-07, NCGC00016349-08, NCGC00094973-01, NCGC00094973-02, NCGC00094973-03, 4CN-0905, AJ-09778, AK111291, AN-42608, CC-34387, LS-55217, NCI60_003834, SC-90283, ST056287, ZB002243, 7-Hydroxy-6-methoxy-2H-chromen-2-one #, Gelseminic acid solution, 20 mM in DMSO, AB0019688, AX8035441, KB-249948, TR-029034, 6-Methylesculetin solution, 20 mM in DMSO, AB00443525, FT-0631451, S0367, ST24045669, C01752, W-3522, 006S872, A844290, C-30831, SR-01000841273-3, SR-01000841273-4, 7-hydroxy-6-methoxycoumarin solution, 20 mM in DMSO, BRD-K96163925-001-06-5, BRD-K96163925-001-09-9, I14-14171, 0B4B9FAA-686D-4977-AA08-65F8E4F1977C, 7-hydroxy-6-methoxychromen-2-one solution, 20 mM in DMSO, Scopoletin, United States Pharmacopeia (USP) Reference Standard

ID: 70

InChIKey: SFLOGVVDXPCWGR-UHFFFAOYSA-N
SMILES: C12=C(NC(=O)C(=O)N1)NC(=NC2=O)N

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10291
synonyms found at PubChem are:
LEUCOPTERIN, Leikopterin, Leukopterin, 492-11-5, 2-Amino-4,6,7-trihydroxypteridine, UNII-54RIE2BQ10, 54RIE2BQ10, 2-amino-5,8-dihydro-1H-pteridine-4,6,7-trione, 4,6,7(3H)-Pteridinetrione, 2-amino-5,8-dihydro-, 2-aminopteridine-4,6,7(3H,5H,8H)-trione, 2-Amino-4,6,7-trihydroxypyrimido(4,5-b)pyrazine, 2-Amino-4,6,7-trihydroxypyrimido[4,5-b]pyrazine, 2-Aminopteridine-4,6,7-triol, EINECS 207-747-3, NSC 93740, 6,7-dihydroxypterin, Spectrum_001136, SpecPlus_000324, Spectrum2_000587, Spectrum3_000761, Spectrum4_001724, Spectrum5_000488, AC1L1UW2, NCIOpen2_001382, BSPBio_002402, KBioGR_002108, KBioSS_001616, DivK1c_006420, SCHEMBL968371, SPECTRUM1500874, SPBio_000434, CHEMBL3039245, SCHEMBL12948394, KBio1_001364, KBio2_001616, KBio2_004184, KBio2_006752, KBio3_001622, 2-Amino-4,7-trihydroxypteridine, DTXSID00197707, MolPort-000-828-206, MolPort-002-511-804, SFLOGVVDXPCWGR-UHFFFAOYSA-N, NSC93740, CCG-38510, NSC-93740, ZINC18247079, AKOS006227881, AKOS022505738, FCH1191668, MCULE-6696393574, SDCCGMLS-0066681.P001, NCGC00095646-01, NCGC00095646-02, FT-0691535, 2-Amino-4,7-trihydroxypyrimido[4,5-b]pyrazine, 4,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro-, 4,7(3H)-Pteridinetrione, 2-amino-5,8-dihydro-, C-55951, 2-Amino-5,8-dihydro-4,6,7(1H)-pteridinetrione #, 4,6,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro-, 4,6,7(1H)-Pteridinetrione, 2-amino-5,8-dihydro- (8CI)(9CI)

ID: 71

InChIKey: SQVXWIUVAILQRH-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5320693
synonyms found at PubChem are:
Pratol, 7-Hydroxy-4'-methoxyflavone, 487-24-1, C.I. 75570, UNII-KU5R959MO7, 4H-1-Benzopyran-4-one, 7-hydroxy-2-(4-methoxyphenyl)-, 7-hydroxy-2-(4-methoxyphenyl)chromen-4-one, EINECS 207-653-2, NSC 123414, 7-Hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, BRN 0237239, MLS002707301, KU5R959MO7, 7-Hydroxy-2-(4-methoxyphenyl)-4-benzopyrone, Flavone, 7-hydroxy-4'-methoxy-, SQVXWIUVAILQRH-UHFFFAOYSA-N, NSC123414, 7-Hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, NSC-123414, Flavone, 7-hydroxy-4'-methoxy- (7CI,8CI), AN-829/40761415, 487-17-2, 7-Hydroxy-4-methoxyflavone, 4hl5, 7-Hydroxy-flavone, 5h, AC1NSZS1, 4'-methoxy-7-hydroxyflavone, Oprea1_854602, CHEMBL16751, SCHEMBL534596, BDBM85573, DTXSID20197587, MolPort-002-903-705, Pratol solution, 100 mM in DMSO, TNP00065, ZINC5733557, ACM487172, AKOS004110700, CCG-208438, MCULE-4757451306, NCGC00017200-01, NCGC00017200-02, NCGC00017200-03, NCGC00142412-01, NCGC00142412-02, LS-39700, SMR001488172, ST055366, Pratol, disposable screening library format, FT-0730316, C-57549, SR-05000002252, 7-Hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one #, SR-05000002252-2, BRD-K35651673-001-05-9, 15W

ID: 72

InChIKey: TZFWDZFKRBELIQ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1Cl)NC(=O)O2

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2733
synonyms found at PubChem are:
chlorzoxazone, 95-25-0, Chlorzoxazon, Paraflex, Chloroxazone, 5-Chloro-2-benzoxazolone, Biomioran, Escoflex, Myoflexin, Myoflexine, Pathorysin, Mioran, Miotran, Neoflex, Solaxin, 2(3H)-Benzoxazolone, 5-chloro-, Parafon Forte DSC, 5-Chloro-2-hydroxybenzoxazole, 5-Chloro-2-benzoxazolinone, Chlorzoxane, 5-Chlorobenzoxazolidone, 5-Chloro-2(3H)-benzoxazolone, Usaf ma-10, 5-Chlorobenzoxazol-2-one, Strifon Forte Dsc, Chlorzoxazonum, 5-Chloro-2-benzoxazolol, 5-Chlorobenzoxazolone, 2-Hydroxy-5-chlorobenzoxazole, 5-Chlorobenzo[d]oxazol-2(3H)-one, Chlorsoxazone, Clorzoxazona, Klorzoxazon, Remofleks, Nyoflex, 5-Chlorbenzoxazolin-2-on, Parafon Forte, 5-Chloro-1,3-benzoxazol-2(3H)-one, 5-chloro-3H-1,3-benzoxazol-2-one, Parafon, 5-Chloro-3(H)-2-benzoxazolone, 5-Chlorobenzoksazolon-2, 5-Chlorobenzoksazolinon-2, 5-chlorobenzoxazolin-2-one, Chlorzoxazonum [INN-Latin], Clorzoxazona [INN-Spanish], chlorzoxazona, Relaxazone, Remular, C7H4ClNO2, 5-Chlorobenzoksazolon-2 [Polish], Remular-S, 5-Chlorobenzoksazolinon-2 [Polish], UNII-H0DE420U8G, 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one, NSC 26189, 2-BENZOXAZOLINONE, 5-CHLORO-, Paraflex (TN), 5-chlorobenzo[d]oxazol-2-ol, Chlorzoxazone [INN:BAN:JAN], 5-chloro-3H-benzooxazol-2-one, 5-chloro-1,3-benzoxazol-2-ol, EZE-DS, EINECS 202-403-9, component of Parafon Forte, CHEMBL1371, AI3-63119, MLS000069380, CHEBI:3655, Chlorzoxazone (JAN/USP/INN), H0DE420U8G, TZFWDZFKRBELIQ-UHFFFAOYSA-N, CAS-95-25-0, NCGC00015238-02, SMR000058269, DSSTox_CID_2813, C 4397, DSSTox_RID_76739, DSSTox_GSID_22813, CLW, 5-chloro-3-hydrobenzoxazol-2-one, Lorzone, SR-01000075207, Clorzoxazone, Phantom, Stealth, Strifon, 5-Chloro-3H-benzoxazol-2-one, Mystox MP, Prestwick_62, Chlorzoxazone,(S), Chlorzoxazone [USP:INN:BAN:JAN], Citrex (acaricide), Muscol (TN), Parafon Forte (TN), PubChem8642, 5-Chlorobenzoxazolinone, Spectrum_000148, AC1L1ECE, Opera_ID_1659, Prestwick0_000163, Prestwick1_000163, Prestwick2_000163, Prestwick3_000163, Spectrum2_001149, Spectrum3_000350, Spectrum4_000287, Spectrum5_000745, Lopac-C-4397, D08ZEB, 5-Chloro-benzooxazol-2-ol, AC1Q3KM0, AC1Q3KM1, Ortho Brand of Chlorzoxazone, 5-chloro-benzoxazolin-2-one, Lopac0_000253, SCHEMBL35177, BSPBio_000025, BSPBio_002019, KBioGR_000814, KBioSS_000628, WLN: T56 BMVOJ HG, McNeil Brand of Chlorzoxazone, DivK1c_000895, SPECTRUM1500188, SPBio_001077, SPBio_001946, BPBio1_000029, GTPL2322, DTXSID9022813, CTK6H1680, HMS502M17, KBio1_000895, KBio2_000628, KBio2_003196, KBio2_005764, KBio3_001239, KS-00000VVL, MolPort-001-759-947, MolPort-006-110-468, NINDS_000895, HMS1568B07, HMS1920O07, HMS2091E14, HMS2095B07, HMS2235I19, HMS3259I15, HMS3260D08, HMS3373P17, HMS3652K22, HMS3712B07, Pharmakon1600-01500188, Secure 360SC Insecticide-Miticide, ACT08248, ALBB-012641, BCP07916, HY-B1462, NSC26189, STR00805, Tox21_110105, Tox21_500253, BBL003952, BDBM50290811, CCG-40323, KM3336, MFCD00005717, NSC-26189, NSC756693, s4155, SBB003864, STK071582, ZINC84843283, AKOS000404381, Tox21_110105_1, component of Parafon Forte (Salt/Mix), CS-5155, DB00356, HG-0202, LP00253, MCULE-3638156868, NC00499, NSC-756693, 5-chloranyl-3H-1,3-benzoxazol-2-one, 5-chloro-1,3-benzoxazole-2(3H)-one, IDI1_000895, Chlorzoxazone 1.0 mg/ml in Acetonitrile, NCGC00015238-01, NCGC00015238-03, NCGC00015238-04, NCGC00015238-05, NCGC00015238-06, NCGC00015238-07, NCGC00015238-08, NCGC00015238-09, NCGC00015238-10, NCGC00015238-13, NCGC00093714-01, NCGC00093714-02, NCGC00093714-03, NCGC00093714-04, NCGC00260938-01, 5-Chloro-1,3-benzoxazol-2(3H)-one #, AC-12192, AN-24309, BP-11613, CPD000058269, KB-88347, LS-42267, SAM002554888, SC-07433, SBI-0050241.P004, AB0011060, AB1004047, ST2406217, AB00051947, AC 303-630, EU-0100253, FT-0620220, ST45024437, EN300-31026, 5-Chloro-2,3-dihydro-2-oxo-1,3-benzoxazole, C07931, D00771, AB00051947_05, AB00051947_06, A845253, I14-4579, SR-01000075207-1, SR-01000075207-3, SR-01000075207-5, W-100168, BRD-K98174813-001-05-7, BRD-K98174813-001-08-1, Z57183224, 5-Chloro-2(3H)-benzoxazolone; 5-Chloro-2-hydroxybenzoxazole, Chlorzoxazone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10, 32850-84-3

ID: 73

InChIKey: UFULAYFCSOUIOV-UHFFFAOYSA-N
SMILES: C(CS)N

biological descriptors:

CFTR relevance: proteostasis regulator (targeting disabled autophagy and CK2 overactivation)

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"L Maiuri" "M Piacentini" "A Tosco" "V Raia" "VR Villella" "G Kroemer"

CID is 6058
synonyms found at PubChem are:
CYSTEAMINE, 2-Aminoethanethiol, Mercaptamine, 60-23-1, Thioethanolamine, Becaptan, Mercamine, Cysteinamine, beta-Mercaptoethylamine, 2-Mercaptoethylamine, Cysteamin, Lambraten, Lambratene, beta-Aminoethanethiol, Cystagon, Riacon, Decarboxycysteine, Mercaptoethylamine, 2-Amino-1-ethanethiol, Cisteamina, 2-Aminoethyl mercaptan, beta-Aminoethylthiol, 2-Mercaptoethanamine, Ethanethiol, 2-amino-, Mercaptamin, (2-Mercaptoethyl)amine, MEA (mercaptan), Ethanethiolamine, beta-MEA, Aminoethyl mercaptan, Mercaptamina, Mercaptaminum, Cysteamide, Mecramine, Mercamin, Merkamin, Cisteamina [Italian], Cystaran, 2-AMINO-ETHANETHIOL, Mercaptaminum [INN-Latin], Mercaptamina [INN-Spanish], 1-Amino-2-mercaptoethylamine, 2-aminoethane-1-thiol, Cysteamine [USAN:BAN], L-1573, Cysteamine (USAN), WR 347, Cystavision, C2H7NS, UNII-5UX2SD1KE2, Cysteamine bitartate, NSC 647528, Cysteamine [USAN], Mercaptamine (INN), CCRIS 3083, HSDB 7353, .beta.-Mercaptoethylamine, EINECS 200-463-0, L 1573, 5UX2SD1KE2, CHEBI:17141, UFULAYFCSOUIOV-UHFFFAOYSA-N, cysteaminium, 2-Mercaptoethylamine, polymer-bound, Mercaptamine [INN], NSC647528, NCGC00015691-03, (Mercaptoethyl)ammonium toluene-p-sulphonate, C-9500, 60-23-1 (Parent), Cystagone, b-Aminoethylthiol, 2-aminoethanethio, b-Aminoethanethiol, mercapto ethylamine, b-Mercaptoethylamine, DHL, 2-amino-ethyl thiol, CASH, .beta.-MEA, Cysteamine, ~95%, Cysteamine, free base, .beta.-Aminoethylthiol, Spectrum_001755, .beta.-Aminoethanethiol, ACMC-1AVBC, SpecPlus_000654, AC1L1LPL, Lopac-M-6500, DSSTox_CID_2875, bmse000388, CHEMBL602, D0V0LB, AC1Q54NL, DSSTox_RID_76770, DSSTox_GSID_22875, KBioSS_002235, KSC490G2L, DivK1c_006750, 156-57-0 (hydrochloride), 641022_ALDRICH, BDBM7968, GTPL7440, 3037-04-5 (tosylate), DTXSID3022875, CTK3J0325, KBio1_001694, KBio2_002235, KBio2_004803, KBio2_007371, KS-00000WES, 42954-15-4 (hydrobromide), Cysteamine, >=98.0% (RT), MolPort-001-662-635, BCP15015, ZINC8034121, EINECS 221-235-7, Tox21_113092, 16904-32-8 (di-hydrochloride), ANW-33452, HY-77591A, STK315355, AKOS003793343, CCG-204834, CS-2799, DB00847, MCULE-1838427828, NE18622, NSC-647528, RP18367, RTR-031658, CAS-60-23-1, NCGC00015691-01, NCGC00015691-02, NCGC00015691-04, NCGC00162236-01, NCGC00162236-02, AN-41805, BP-13401, KB-20296, LS-65761, NCI60_002000, SC-18413, SBI-0050727.P003, 27761-19-9 (tartrate (1:1)), 93965-19-6 (maleate (1:1)), AB0020070, DB-053562, TR-031658, A0648, FT-0611243, V0810, C01678, D03634, AB00053754_09, AB00053754_10, 106791-EP2292597A1, 106791-EP2295407A1, 106791-EP2298736A1, 213515-EP2371809A1, F0001-1576, 2DFDA1F8-7010-4225-8280-AB1C4C43F546, 139720-70-0, 2-Mercaptoethylamine, polymer-bound, 70-90 mesh, extent of labeling: 0.6-1.1 mmol/g loading, 1 % cross-linked with divinylbenzene, 2-ammonioethanethiolate, STL455134

ID: 74

InChIKey: UILPJVPSNHJFIK-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=C(C=C1)OC)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11092
synonyms found at PubChem are:
PAEONOL, 552-41-0, 2'-Hydroxy-4'-methoxyacetophenone, 1-(2-Hydroxy-4-methoxyphenyl)ethanone, Peonol, 2-Hydroxy-4-methoxyacetophenone, 1-(2-hydroxy-4-methoxyphenyl)ethan-1-one, Resacetophenone-4-methyl ether, Ethanone, 1-(2-hydroxy-4-methoxyphenyl)-, Paeonal, Paeonolum, 4-O-Methylresacetophenone, UNII-3R834EPI82, 4-Methoxy-2-hydroxyacetophenone, 4'-Methoxy-2'-hydroxyacetophenone, Resacetophenone, 4-O-methyl ester, EINECS 209-012-2, NSC 401442, Acetophenone, 2'-hydroxy-4'-methoxy-, BRN 1282794, 1-(2-hydroxy-4-methoxy-phenyl)ethanone, AI3-10581, CHEMBL1079227, CHEBI:69581, UILPJVPSNHJFIK-UHFFFAOYSA-N, 3R834EPI82, 1-[2-hydroxy-4-(methyloxy)phenyl]ethanone, Acetophenone, 2'-hydroxy-4'-methoxy- (7CI,8CI), 1-acetyl-2-hydroxy-4-methoxybenzene, Paeonol (Peonol), PubChem3271, ACMC-209lls, AC1L1WLK, Spectrum2_001981, Spectrum3_001686, 2-acetyl-5-methoxyphenol, 2-Acetyl-5-methoxy-phenol, AC1Q48VN, AC1Q48VO, CBiol_000986, BSPBio_003212, 4-08-00-01793 (Beilstein Handbook Reference), KSC490C8B, MLS006011902, SPECTRUM1601021, SPBio_002161, SCHEMBL1449478, ZINC1906, DTXSID1022059, CTK3J0180, KBio3_002432, 4-methoxy 2-hydroxy acetophenone, MolPort-001-537-637, HMS3656E07, 2;-Hydroxy-4;-methoxyacetophenone, ACN-S003528, ACT07801, HY-N0159, KS-000004VU, ANW-32270, BBL012127, BDBM50310718, CCG-39471, CP0063, ICCB4_000282, MFCD00008730, NSC401442, s2339, SBB066134, STK078097, AKOS000119646, AC-7982, ACN-027221, AN-1408, AS05193, MCULE-2846207321, NSC-401442, RP02462, RTC-067540, SDCCGMLS-0066845.P001, TRA0005840, 1-(2-hydroxy-4-methoxyphenyl)-ethanone, NCGC00095977-01, NCGC00095977-02, NCGC00095977-03, 1-(2-hydroxy-4-methoxy-phenyl)-ethanone, 2'-Hydroxy-4'-methoxyacetophenone, 99%, 4CN-0677, AJ-08110, AS-15489, CJ-00070, P565, SC-05288, SMR000112386, SY013508, 1-(2-Hydroxy-4-methoxyphenyl)ethanone #, 1-(4-Methoxy-2-hydroxy-phenyl)-ethanone, AB0044007, KB-146762, LS-101156, TC-067540, 1-(2-hydroxy-4-methoxyphenyl)ethane-1-one, AM20040702, FT-0602529, FT-0618875, N1847, ST24021015, ST45027685, C10712, M-2917, 552H410, Ethanone, 1-(2-hydroxy-4-methoxyphenyl)- (9CI), SR-05000002397, I06-0541, Q-100626, SR-05000002397-1, 2-HYDROXY-4-METHOXYACETOPHENONE (4,4,4-D3), BRD-K94239562-001-02-2, BRD-K94239562-001-03-0, InChI=1/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H

ID: 75

InChIKey: VPJJUDAXEIWYQR-UHFFFAOYSA-N
SMILES: C1CCCC2SC(NC(=O)C3=CC=CC=C3Cl)=C(C(=O)N)C1=2

biological descriptors:

CFTR relevance: strong CFTR potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"VS Gopinath" "RK Guy" "AS Verkman" "H Yang" "AA Shelat" "A Taddei" "C Folli" "K Du" "T Ma" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 723141
synonyms found at PubChem are:
CHEMBL210832, 2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, 298193-32-5, 2-[(2-chlorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, BAS 00568157, CBMicro_048310, dF508act-02, AC1LF54M, AC1Q4Z7D, Cambridge id 5367707, Oprea1_211305, Oprea1_265080, SCHEMBL3110880, MolPort-000-224-232, VPJJUDAXEIWYQR-UHFFFAOYSA-N, ZINC127920, BDBM50185114, STL282684, AKOS000291649, MCULE-3529042180, ACM298193325, KB-13984, BIM-0048269.P001, KB-113545, EU-0035371, ST50003514, SR-01000404669, SR-01000404669-1, F0016-0638, 2-(2-Chlorobenzoylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acidamide, 2-[(2-chlorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxamide, 2-[(2-chlorophenyl)carbonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbox amide, 2-{[(2-chlorophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, 2-C-(2-chlorobenzene)-4,5,6,7-tetrahydro-1-benzothiophene-2,3-dicarboxamide

ID: 76

InChIKey: VWENUKHWZBZSLW-UHFFFAOYSA-N
SMILES: CC1CC(CC(N1C)(C)C)OC(=O)C(C2=CC=CC=C2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 102428
synonyms found at PubChem are:
Eucatropine hydrochloride, 536-93-6, EUCATROPINE HCl, 1,2,2,6-tetramethylpiperidin-4-yl 2-hydroxy-2-phenylacetate hydrochloride, UNII-560X8YZ82N, 1,2,2,6-Tetramethyl-4-piperidyl mandelate hydrochloride, MLS000863285, 560X8YZ82N, SMR000058649, DSSTox_CID_25828, DSSTox_RID_81157, DSSTox_GSID_45828, Eucatropine hydrochloride [USP], EINECS 208-653-5, Eucatropinhydrochlorid, Prestwick_1058, Opera_ID_782, AC1L2SRM, AC1Q3EAR, Euphthalmine hydrochloride, NCGC00016499-01, CAS-536-93-6, AC1Q39KC, MLS000069821, MLS002222297, SCHEMBL636552, CHEMBL1372791, DTXSID6045828, HMS1570O10, Tox21_111313, Tox21_113348, 6413AF, AKOS027420446, Tox21_113348_1, API0008558, CCG-220794, Eucatropine hydrochloride (USP XXXII), NCGC00179372-03, FT-0632333, D04116, C-50809, SR-01000759140, SR-01000759140-2, 4-Mandeloyloxy-1,2,2,6-tetramethylpiperidine hydrochloride, alpha-Hydroxybenzeneacetic acid 1,2,6-tetramethyl-4-piperidinyl ester, (1,2,2,6-tetramethylpiperidin-4-yl) 2-hydroxy-2-phenylacetate hydrochloride, Benzeneacetic acid, alpha-hydroxy-, 1,2,2,6-tetramethyl-4-piperidinyl ester hydrochloride

ID: 77

InChIKey: WIIZWVCIJKGZOK-RKDXNWHRSA-N
SMILES: C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5959
synonyms found at PubChem are:
chloramphenicol, Chloromycetin, 56-75-7, Chlornitromycin, Levomycetin, Chlorocid, Halomycetin, Levomicetina, Alficetyn, Fenicol, Globenicol, Chloroamphenicol, Aquamycetin, Chloramex, Chlorocol, Detreomycin, Oleomycetin, Chloramficin, Chloramfilin, Chloroptic, Cloramicol, D-Chloramphenicol, Embacetin, Enteromycetin, Juvamycetin, Leukomycin, Sificetina, Anacetin, Chlomin, Mychel, Chloramphenicolum, Chloronitrin, Ciplamycetin, Detreomycine, Dextromycetin, Intramycetin, Laevomycetinum, Levomitsetin, Mediamycetine, Micochlorine, Novophenicol, Stanomycetin, Amphenicol, Amphicol, Amseclor, Austracil, Austracol, Biocetin, Biophenicol, Chemicetin, Chemicetina, Chlomycol, Chloramsaar, Chlorasol, Chloricol, Chlorocaps, Chlorocide, Chlorovules, Cidocetine, Cloramficin, Cloramidina, Clorocyn, Cloromisan, Clorosintex, Comycetin, Cylphenicol, Doctamicina, Econochlor, Erbaplast, Farmicetina, Hortfenicol, Isicetin, Ismicetina, Isophenicol, Kemicetina, Kemicetine, Leukomyan, Loromisin, Mastiphen, Medichol, Micloretin, Micoclorina, Microcetina, Novomycetin, Ophthochlor, Pantovernil, Rivomycin, Ambofen, Catilan, Desphen, Emetren, Enicol, Ertilen, Glorous, Kamaver, Klorita, Paraxin, Isopto fenicol, Chlora-tabs, Chlorocidin C, Chloroject L, Normimycin V, Chlorocid S, Klorocid S, Mychel-Vet, Chloramfenikol, Cloramfenicol, Novochlorocap, Sintomicetina, Synthomycetin, Chloromax, Oftalent, Otachron, Pentamycetin, Quemicetina, Romphenil, Ronphenil, Septicol, Chloro-25 vetag, Mycinol, Opclor, Otophen, Sintomicetine R, Sno-Phenicol, Chlorocidin C tetran, Cloroamfenicolo, Veticol, D-(-)-Chloramphenicol, Chloromycetny, Cloramfenicolo, Synthomycetine, Treomicetina, Chlorofair, Optomycin, Syntomycin, Tevcocin, Tifomycine, Unimycetin, Viceton, Cloranfenicol, Kloramfenikol, Tiromycetin, Cloramfen, Leukamycin, Loromisan, Tifomycin, CAF (pharmaceutical), Ak-chlor, Chloramfenikol [Czech], Chloromycetny [Polish], D-(-)-threo-Chloramphenicol, Cloramfenicolo [DCIT], Tega-Cetin, Chlorbiotic (Veterinary), I 337A, Cloroamfenicolo [Italian], Chloramphenicol crystalline, Elase-Chloromycetin, Chloramphenicol, d-, U-6062, NCI-C55709, NSC 3069, Chloroptic S.O.P., Cloramfenicol [INN-Spanish], Chloramphenicolum [INN-Latin], Chemiceticol, Cloramical, Cloromissan, D-threo-Chloramphenicol, Duphenicol, Interomycetine, Intramyctin, Loromicetina, Ophtochlor, Synthomycine, Chlorsig, Ronfenil, Tevcosin, Myscel, Opelor, Chlormycetin R, F armicetina, Ch loramex, Sno Phenicol, Vice ton, Tea-Cetin, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, D(-)-threo-Chloramphenicol, Econochlor (TN), CAF, Chloromyxin, Amphicol (TN), Chloromycetin (TN), C11H12Cl2N2O5, CCRIS 3922, UNII-66974FR9Q1, CHEBI:17698, Chloramphenicol [INN:BAN:JAN], D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol, HSDB 3027, NSC3069, CHLOROPTIC S.O.P, EINECS 200-287-4, NSC 16331, D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol, BRN 2225532, C.A.F, 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, AI3-25003, D-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide, Chloramphenicol (Chloromycetin), D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, WIIZWVCIJKGZOK-RKDXNWHRSA-N, D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, 2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, 66974FR9Q1, NCGC00091011-05, D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DSSTox_CID_265, D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-N-(1,1'-Dihydroxy-1-p-nitrophenylisopropyl)dichloroacetamide, 2,2-Dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide, DSSTox_RID_75473, DSSTox_GSID_20265, Mycochlorin, Ocuphenicol, Chlorocin, Levocin, Levoplast, Levosin, Levovetin, Myclocin, Soluthor, ACETAMIDE, 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-, CLM, Chloramphenicole, D(-)-threo-2-dichloroacetamido-1-p-nitrophenyl-propanediol, D(-)-threo-2-dichloroacetamido-1-p-nitrophen yl-propanediol, D(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, (-)-chloramphenicol, Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-4-nitrophenethyl]acetamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2,2-dichloroace tamide, Ophthocort (Salt/Mix), Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (theta-(theta,theta))-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-beta-(4-nitrophenyl)ethyl]acetamide, SMR000471851, Chloromyxin (Salt/Mix), CHLORAMPHENICOL LEVO, SR-01000761450, Elase-Chloromycetin (Salt/Mix), chioramphenicol, chlorocidin, cloramphenicol, D-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, CAS-56-75-7, Kemicetine (TN), Silmycetin (TN), Tifomycine (TN), Vernacetin (TN), Alficetyn (TN), Cedoctine (TN), Chloramex (TN), Nevimycin (TN), NCGC00094620-01, Biomicin (TN), Brochlor (TN), Chlorsig (TN), Phenicol (TN), Thiamphenicol,(S), D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl))-p-nitrophenethylacetamide, D-(-)-threo-2,2-Dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)]-p-nitrophenethylacetamide, Laevomycetin (TN), Synthomycine (TN), Fenicol (TN), Medicom (TN), Renicol (TN), Veticol (TN), Golden Eye (TN), Orchadexoline (TN), Chloramphenicol [USP:INN:BAN:JAN], Chloramphenicol,(S), Isoptophenicol (TN), Oftan Chlora (TN), Chlornitromycin (TN), Chloromycetin&#174, Dispersadron C (TN), PubChem20321, CHLOROMYCETIN(R), Prestwick3_000031, CHEMBL130, D0X6IU, Epitope ID:114066, AC1L1LI3, Optrex Infected Eyes (TN), SCHEMBL16111, BSPBio_000121, WLN: WNR DYQY1QMVYGG, 4-13-00-02742 (Beilstein Handbook Reference), Chloramphenicol & VRC3375, D-2-DICHLOROACETAMIDO-1-p-NITRO-PHENYL-1,3-PROPANEDIOL, MLS001055372, MLS001066397, MLS001332385, MLS001332386, MLS002222155, ARONIS23913, BIDD:GT0145, DivK1c_000544, BPBio1_000135, D-(-)-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol, D-(-)-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, DTXSID7020265, BDBM23447, Chloramphenicol, gamma-irradiated, CTK4B4374, HMS501L06, KBio1_000544, KS-00000XTX, BBC/192, BIC0113, MolPort-001-794-646, NINDS_000544, ZX-AFC000642, Chloramphenicol (JP15/USP/INN), Chloramphenicol (JP17/USP/INN), HMS2090M15, HMS2095G03, HMS2269N06, HMS3712G03, ZINC113382, Chloramphenicol, >=98% (HPLC), 2787-09-9, Acetamide, 2,2-dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-, Acetamide, 2,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, BCP12150, D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, HY-B0239, NSC-3069, RKL10087, Tox21_111306, Tox21_400061, LS-225, MFCD00078159, s1677, SBB057728, AKOS005111001, AB02994, CCG-220031, CS-2207, DB00446, MCULE-7778960570, IDI1_000544, KS-000048O2, SMP1_000065, NCGC00091011-01, NCGC00091011-02, NCGC00091011-03, NCGC00091011-04, NCGC00091011-06, NCGC00091011-08, NCGC00091011-09, 85666-84-8, AK174225, AN-23562, AS-14683, CC-25647, CPD000471851, M163, NCI60_002620, SAM002589931, SC-18476, ST024743, AB0015087, AB1009524, Chloramphenicol, puriss., 98.0-102.0%, AB00374860, Chloramphenicol 10 microg/mL in Acetonitrile, Chloramphenicol, tested according to Ph.Eur., FT-0602995, Chloramphenicol 100 microg/mL in Ethylacetate, C-3307, C00918, D00104, W-2830, AB00374860-13, AB00374860-14, AB00374860_15, Chloramphenicol, meets USP testing specifications, C-19742, Chloramphenicol, VETRANAL(TM), analytical standard, SR-01000761450-2, SR-01000761450-3, SR-01000761450-5, BRD-K08111712-001-02-7, BRD-K08111712-001-16-7, Chloramphenicol, Antibiotic for Culture Media Use Only, Alficetyn, Chlornitromycin, Chloromycetin, Chloramphenicol, Chloramphenicol, BioReagent, suitable for plant cell culture, Chloramphenicol, certified reference material, TraceCERT(R), Chloramphenicol, British Pharmacopoeia (BP) Reference Standard, Chloramphenicol, European Pharmacopoeia (EP) Reference Standard, Chloramphenicol, United States Pharmacopeia (USP) Reference Standard, D-(-)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-threo-N-dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propane-diol, CHLORAMPHENICOL (SEE ALSO CHLORAMPHENICOL NA SUCCINATE 982-57-0), D-( -)-threo-1-(p-nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL, 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propyl]acetamide, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl], Chloramphenicol, Biotechnology Performance Certified, suitable for plant cell culture, D-(-)-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide, D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxy-methyl)-p-nitrophenethyl]acetamide, 137731-90-9, 15313-32-3, 2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(hydroxy(oxido)amino)phenyl)ethyl)acetamide, (1R, 2R)-, 55172-72-0, 59112-59-3, Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R*,R*)-(+-)-, Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-,D-(-)-threo-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]-, [R-(R*,R*)]-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-, Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-,D-(-)-threo-, Acetamide,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, D-(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE, D-(-)-threo-alpha, alpha-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE

ID: 78

InChIKey: WUADCCWRTIWANL-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O

biological descriptors:

CFTR relevance: ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 5280373
synonyms found at PubChem are:
biochanin A, 491-80-5, Biochanin, 4'-Methylgenistein, 5,7-Dihydroxy-4'-methoxyisoflavone, 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one, Genistein 4-methyl ether, Pratensol, Biochanine A, 5,7-Dihydrox -4'-methoxyisoflavone, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-methoxyphenyl)-, olmelin, Biochanin-A, 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one, 4-Methylgenistein, C16H12O5, NSC 123538, UNII-U13J6U390T, CCRIS 5449, 5,7-Dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one, EINECS 207-744-7, NSC123538, Genistein 4'-methyl ether, Isoflavone, 5,7-dihydroxy-4'-methoxy-, MLS000069443, CHEMBL131921, CHEBI:17574, WUADCCWRTIWANL-UHFFFAOYSA-N, U13J6U390T, 4'-Methoxy-5,7-dihydroxy isoflavone, NSC-123538, SMR000059116, Apigenin 4-Methyl Ether, DSSTox_CID_2394, DSSTox_RID_76570, DSSTox_GSID_22394, Q-100552, CAS-491-80-5, SR-01000003021, QSO, Biochanin A, 9, Biochanin A (BCA), AC1NQWYN, Spectrum_000195, Opera_ID_621, Spectrum2_000047, Spectrum3_001098, Spectrum4_001927, Spectrum5_001624, D02UQX, D0S9YX, Oprea1_038096, SCHEMBL61258, BSPBio_002776, KBioGR_002274, KBioSS_000675, MLS001148446, MLS006011785, BIDD:ER0123, DivK1c_001027, SPBio_000173, BDBM9461, GTPL2829, DTXSID1022394, SPECTRUM10100003, Biochanin A (4-Methylgenistein), Biochanin A - 4-Methylgenistein, cid_5280373, HMS503M15, KBio1_001027, KBio2_000675, KBio2_003243, KBio2_005811, KBio3_001996, 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one, MolPort-000-424-557, NINDS_001027, HMS2232N19, HMS3369A02, HMS3656A13, TNP00319, Isoflavone,7-dihydroxy-4'-methoxy-, Tox21_202097, Tox21_302901, 5,7-Dihydrox-4''-methoxyisoflavone, BBL010523, CCG-38351, LMPK12050229, MFCD00006839, s2377, STK888295, ZINC18847037, 5,7-dihydroxy-4'-methoxy-Isoflavone, 5,7-Dihydroxy-4/'-methoxyisoflavone, AKOS002163860, API0001717, CS-3082, MCULE-6764919720, IDI1_001027, KS-00000I00, SMP1_000045, NCGC00017369-01, NCGC00017369-02, NCGC00017369-03, NCGC00017369-04, NCGC00017369-05, NCGC00017369-06, NCGC00017369-07, NCGC00017369-08, NCGC00017369-09, NCGC00017369-10, NCGC00022428-03, NCGC00022428-04, NCGC00022428-05, NCGC00178478-01, NCGC00256458-01, NCGC00259646-01, AC-22309, AJ-70675, AK155884, AN-45276, AS-17474, HY-14595, KB-79569, LS-39601, NCI60_000558, ST057580, Biochanin A, analytical reference material, AB1004489, AX8016263, B4098, FT-0663120, N1308, V0303, 5,7-dihydroxy-4'-methoxy-Isoflavone (8CI), C00814, X-2593, Isoflavone, 5,7-dihydroxy-4'-methoxy- (8CI), 491B805, 5,7-Dihydroxy-4'-methoxyisoflavone, 98% 250mg, SR-01000003021-4, SR-01000003021-5, BRD-K73303757-001-02-6, BRD-K73303757-001-12-5, I14-13389, 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one #, F1190-0491, 4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-methoxyphenyl)-, 2AA2D226-B323-4AE2-B576-2D47D15F9845, Biochanin A, United States Pharmacopeia (USP) Reference Standard, 5,7-Dihydroxy-4 inverted exclamation marka-methoxyisoflavone; Genistein 4 inverted exclamation marka-methyl ether

ID: 79

InChIKey: WXNXCEHXYPACJF-ZETCQYMHSA-N
SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 70912
synonyms found at PubChem are:
N-Acetyl-L-leucine, 1188-21-2, acetyl-L-leucine, Ac-Leu-OH, N-Acetylleucine, (S)-2-Acetamido-4-methylpentanoic acid, (2S)-2-acetamido-4-methylpentanoic acid, N-acetyl-leucine, N-acetyl-Leu, Leucine, N-acetyl-, L-, n-acetyl-L-leucin, UNII-E915HL7K2O, Leucine, N-acetyl-, NSC 206316, acetyl leucine, (S)-2-Acetylamino-4-methyl-pentanoic acid, E915HL7K2O, (2S)-2-(acetylamino)-4-methylpentanoic acid, CHEBI:17786, WXNXCEHXYPACJF-ZETCQYMHSA-N, CAS-1188-21-2, DSSTox_CID_25870, DSSTox_RID_81188, DSSTox_GSID_45870, L-Acetylleucine, acetyl-leucine, NCGC00094935-01, EINECS 214-706-3, N-acetyl-(L)-leucine, PubChem10962, Spectrum_001313, AC1Q1OAJ, Maybridge1_002565, Prestwick0_000896, Prestwick1_000896, Prestwick2_000896, Prestwick3_000896, Spectrum2_000475, Spectrum3_001480, Spectrum4_000036, Spectrum5_001242, AC1Q5JR5, BSPBio_000712, BSPBio_003039, KBioGR_000471, KBioSS_001793, KSC174M9H, CHEMBL56021, DivK1c_000622, DivK1c_001317, SCHEMBL282372, SPECTRUM1502001, SPBio_000610, SPBio_002921, AC1L2F51, BPBio1_000784, DTXSID6045870, CTK0H4693, HMS501P04, HMS548M13, KBio1_000622, KBio2_001793, KBio2_004361, KBio2_006929, KBio3_002539, MolPort-001-792-394, NINDS_000622, HMS1570D14, HMS1921B16, HMS2097D14, HMS3714D14, Pharmakon1600-01502001, ZINC135384, ACT06842, Tox21_111362, ANW-17243, CCG-40254, MFCD00065131, NSC758152, SBB017526, AKOS000302149, AKOS010400978, Tox21_111362_1, MCULE-9082534218, NSC-758152, RL06123, RP23556, RTC-066514, RTC-066612, CDS1_000277, IDI1_000622, KS-0000011X, NCGC00016567-01, NCGC00016567-02, NCGC00016567-03, NCGC00016567-05, AC-22375, AJ-12258, AN-48789, BAS 16579175, BR-47478, KB-47114, SC-09640, SY013106, (2S)-2-acetamido-4-methyl-pentanoic acid, SBI-0051693.P002, AB1006929, N-Acetyl-L-leucine, ReagentPlus(R), 99%, TC-066514, TL8007017, (S)-2-Acetylamino-4-methyl-pentanoi c acid, A0098, AB00513952, AM20080126, BB 0256992, CS-0007651, FT-0629837, ST24032095, A-1460, C02710, M-6265, 33786-EP2295055A2, 33786-EP2311453A1, 33789-EP2295055A2, 33789-EP2311453A1, 34104-EP2295055A2, 34104-EP2311453A1, 74039-EP2305641A1, 74039-EP2308869A1, AB00052251_03, 118717-EP2277858A1, 118717-EP2298747A1, 188A212, N-Acetyl-L-leucine, Vetec(TM) reagent grade, 98%, BRD-K27406233-001-05-1, UNII-K76S41V71X component WXNXCEHXYPACJF-ZETCQYMHSA-N, 24160-46-1, 90243-88-2

ID: 80

InChIKey: XJGFWWJLMVZSIG-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)N

biological descriptors:

CFTR relevance: CFTR proteostasis regulator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction indirect
subcellular compartment several

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"AI Esposito" "U Pfeffer" "E Sondo" "E Caci" "LJ Galietta" "V Tomati" "N Pedemonte"

CID is 7019
synonyms found at PubChem are:
9-AMINOACRIDINE, Acridin-9-amine, Aminacrine, 90-45-9, 9-Acridinamine, Aminoacridine, Aminacrin, Izoacridina, Monacrin, Aminoacridina, Aminoacridinum, 10-Amino-5-azaanthracene, 9-Acridinylamine, 9-Aminoakridin, Acridine, 9-amino-, 9-Aminoacridin, 9(10H)-Acridinimine, 9-Aminoakridin [Czech], Aminoacridine [INN:BAN], 9AA, UNII-78OY3Z0P7Z, NSC 13000, CCRIS 748, Acridin-9-ylamine, NSC 7571, EINECS 201-995-6, BRN 0141171, AI3-51012, 78OY3Z0P7Z, 9-AA, CHEBI:74789, XJGFWWJLMVZSIG-UHFFFAOYSA-N, acridine-9-ylamine, Aminopt, Mykocert, 110166-26-2, CS-003/03975023, WLN: T C666 BNJ IZ, MLS000780068, NSC7571, 7AD, 8AD, 9-Aminoacridine hydrochloride hydrate, acridin-9-amine;hydrate;hydrochloride, SMR000420251, iminoacridan, 5-Aminoacridin, 9-amino acridine, 4bds, 9-Amino-acridine, F2179-0009, acridin-9-yl-amine, Quench (Salt/Mix), ACMC-20mczt, Mycosert (Salt/Mix), Spectrum_001108, SpecPlus_000861, 9-Acridinamine (9CI), AC1L1NTJ, Spectrum2_001112, Spectrum3_000617, Spectrum4_000580, Spectrum5_001498, AC1Q4W9J, AC1Q51BO, Acramine Yellow (Salt/Mix), SCHEMBL14999, BSPBio_002154, KBioGR_001020, KBioSS_001588, BIDD:GT0816, CHEMBL43184, DivK1c_006957, SPECTRUM1500810, SPBio_001244, DTXSID2024456, BDBM72700, cid_2723598, CTK0G2217, KBio1_001901, KBio2_001588, KBio2_004156, KBio2_006724, KBio3_001654, KS-00000GTZ, XJGFWWJLMVZSIG-UHFFFAOYSA-, MolPort-001-738-830, HMS1921I16, HMS2092K22, HMS3715H04, Pharmakon1600-01500810, 9-acridinamine;hydrate;hydrochloride, ALBB-020726, BCP25849, HY-B1422, NSC13000, NSC28747, ZX-AN019316, ANW-75188, BBL011755, CCG-39037, NSC-13000, NSC-28747, NSC757794, SBB003606, STK387428, ZINC19014768, AKOS000120447, acridin-9-ylamine;hydrate;hydrochloride, CS-4915, DB11561, LS-1913, MCULE-4734217474, NSC-757794, NCGC00094857-01, NCGC00094857-02, NCGC00094857-03, AJ-45955, AK109135, AS-17405, CC-23490, ST093685, U978, 9-AMINOACRIDINE (5-AMINOACRIDINE), SBI-0051612.P002, AX8014518, DB-026983, KB-250613, TC-163933, A2905, FT-0621612, ST24045903, EN300-17076, M-2337, AB00052180_09, AB00052180_10, C-08694, SR-01000760844, CU-01000012501-2, SR-01000760844-2, BRD-K00535541-001-02-2, BRD-K00535541-311-04-1, 9-AMINO-(N-(2-DIMETHYLAMINO)BUTYL)ACRIDINE-4-CARBOXAMIDE, 9-Aminoacridine, matrix substance for MALDI-MS, >=99.5% (HPLC), 9-AMINOACRIDINE (SEE ALSO 9-AMINOACRIDINE HCL AND 9-AMINOACRIDINE HCL-H2O), 148651-03-0, InChI=1/C13H10N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,(H2,14,15)

ID: 81

InChIKey: XSDQTOBWRPYKKA-UHFFFAOYSA-N
SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N

biological descriptors:

CFTR relevance: induces depolarization

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"L Qian" "AS Verkman" "Y Song" "D Salinas" "LJ Galietta" "N Pedemonte" "ND Sonawane"

"AM Van Heeckeren" "ML Drumm" "RC Boucher" "JR Riordan" "A Mengos" "M Gentzsch" "MR Knowles" "SH Randell" "SE Gabriel" "BR Grubb"

CID is 16231
synonyms found at PubChem are:
AMILORIDE, Amipramidin, Midamor, 2609-46-3, Guanamprazine, Amilorida, Amipramizid, Amipramizide, Guanamprazin, Amiloridum, Amyloride, Amiloridum [INN-Latin], Amilorida [INN-Spanish], Amiloride HCL, Amiloride [INN:BAN], N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide, 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, Amiprazidine, C6H8ClN7O, UNII-7DZO8EB0Z3, Amiclaran (TN), Amiloride (INN), CCRIS 6545, EINECS 220-024-7, N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid, Amiloride hydrochloride hydrate, CHEMBL945, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, 7DZO8EB0Z3, CHEBI:2639, 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide, Amikal (Hydrochloride dihydrate), Midamor (Hydrochloride dihydrate), XSDQTOBWRPYKKA-UHFFFAOYSA-N, 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide, MK-870 (Hydrochloride dihydrate), N-amidino-3,5-diamino-6-chloro-2-pyrazinecarboxamide, NCGC00015089-08, AMIPRAMIDINE, DSSTox_CID_23853, DSSTox_RID_80077, Amiloride Hydrocholride, DSSTox_GSID_43853, AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8)), 3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, 137053-86-2, CAS-2609-46-3, Amiclaran, Amilorid, (3,5-diamino-6-chloropyrazin-2-yl)-N-(???methyl)carboxamide, Biduret (TN), Spectrum_000034, Tocris-0890, 1f5l, AC1Q3POC, Prestwick0_000007, Prestwick1_000007, Prestwick2_000007, Prestwick3_000007, Spectrum2_000118, Spectrum3_000293, Spectrum4_000132, Spectrum5_000776, Lopac-A-7410, D0I0RJ, AC1L27IZ, Lopac0_000111, SCHEMBL27562, BSPBio_000013, BSPBio_001572, BSPBio_001826, KBioGR_000292, KBioGR_000544, KBioSS_000292, KBioSS_000394, MLS001060798, BIDD:GT0466, DivK1c_000182, SPBio_000136, SPBio_001934, BPBio1_000015, GTPL2421, DTXSID9043853, BCBcMAP01_000101, BDBM16173, KBio1_000182, KBio2_000292, KBio2_000394, KBio2_002860, KBio2_002962, KBio2_005428, KBio2_005530, KBio3_000583, KBio3_000584, KBio3_001326, Amiloride (Na-Ca chanel blocker), MolPort-005-934-472, NINDS_000182, 17440-83-4 (hydrochloride), Bio1_000359, Bio1_000848, Bio1_001337, Bio2_000292, Bio2_000772, HMS1791O14, HMS1989O14, HMS2089H05, HMS2213E05, HMS3355K04, ACT05635, ACT05652, BCP16815, HY-B0285, ZINC4340269, Tox21_110080, BBL028157, SBB037856, STL373007, AKOS015961348, Tox21_110080_1, API0000380, CCG-204206, CS-2297, DB00594, LS-1094, MCULE-5948863568, 2016-88-8 (anhydrous hydrochloride), IDI1_000182, IDI1_034042, NCGC00015089-01, NCGC00015089-02, NCGC00015089-03, NCGC00015089-04, NCGC00015089-05, NCGC00015089-06, NCGC00015089-07, NCGC00015089-09, NCGC00015089-11, NCGC00015089-12, NCGC00015089-13, NCGC00015089-14, NCGC00015089-15, NCGC00015089-16, NCGC00015089-17, NCGC00024443-02, NCGC00024443-05, NCGC00024443-06, NCGC00024443-07, NCGC00024443-09, AC-13631, SMR000486264, ST079279, U460, (3,5-Diamino-6-chloropyrazinoyl)guanidine, SBI-0050099.P004, N-amidino-3,5-diamino-6-chloropyrazinamide, AB00053415, FT-0703177, C06821, D07447, EN300-149459, AB00053415-24, AB00053415-25, AB00053415_26, AB00053415_27, AB00053415_28, 117188-EP2277879A1, 117188-EP2298776A1, 609A463, J-016249, BRD-K97181089-003-02-3, BRD-K97181089-310-03-0, N-amidino 3,5-diamino-6-chloro-2-pyrazinecarboxamide, F2173-0531, 3,5-diamino-N-carbamimidoyl-6-chloro-pyrazine-2-carboxamide, 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride

ID: 82

InChIKey: XUIIKFGFIJCVMT-LBPRGKRZSA-N
SMILES: C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5819
synonyms found at PubChem are:
L-thyroxine, levothyroxine, 51-48-9, thyroxine, thyroxin, synthroid, Tetraiodothyronine, Thyrax, 3,3',5,5'-Tetraiodo-L-thyronine, Thyratabs, Thyreoideum, Thyroxinal, Thyroxine iodine, Levothyroxin, (-)-Thyroxine, L-Thyroxin, L-T4, Thyroxine (l), Levothyroxine sodium, 3,5,3',5'-Tetraiodo-L-thyronine, levothroid, Levoxyl, DL-Thyroxin, Thyroxine (VAN), eltroxin, 3,5,3',5'-Tetraiodothyronine, Laevothyroxinum, Tetramet, T4 (Hormone), Thyroxine I 125, L-3,5,3',5'-Tetraiodothyronine, Levothyroxinum (acid), t4, Laevothyroxinum (acid), Thryroxine, l-, Oroxine, Levo-T, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, Forthyron (TN), Thyroxine [BAN], Laevoxin, Levolet, Levothyrox, Thyroxevan, Synthroid sodium, Levothyroxinum, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine, 3,3',5,5''-Tetraiodo-L-thyronine, CCRIS 6739, Henning, HSDB 3108, L-Thryoxin, T4 levothyroxine, 3,5,3'5'-Tetraiodo-L-thyronine, THX, UNII-Q51BO43MG4, NSC 36397, Prestwick_548, 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine, Levothyroxine (BAN), Thyroxine sodium, CHEBI:18332, O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, EINECS 200-101-1, 3-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)alanine, beta-((3,5-Diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl)alanine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine, Synthroid (*Sodium salt*), BRN 2228515, CHEMBL1624, (125I)T4, (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid, Q51BO43MG4, UNII-7U4LEE5872, XUIIKFGFIJCVMT-LBPRGKRZSA-N, Levothyroxine Sodium (L-thyroxine), C15H11I4NO4, NCGC00164336-01, CPD000059176, Synthroid (TN), Levoxyl (TN), DSSTox_CID_3214, T-3850, (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoic acid, DSSTox_RID_76927, DSSTox_GSID_23214, Eutirox, Thyroxine, L-, 7U4LEE5872, levothyroxine sodium pentahydrate, (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid, 2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid, LT4, SMR000059176, T44, 24486-40-6, 7488-70-2, Levothyroxine [INN:BAN], Forthyron, SR-01000759430, 2ceo, CAS-51-48-9, Eltroxin (TN), Euthyrox (TN), levothyroxin natrium, Eutirox (TN), Levaxin (TN), Thyroxine, labeled with iodine-125, L-thyroxine (TN), Thyrax (TN), Thyrox (TN), Spectrum_001076, 1hk1, 1hk2, 1hk3, 1hk4, 1hk5, 1y0x, L-Thyroxine, free acid, SpecPlus_000871, Thyroxine, L-(8CI), Prestwick0_000403, Prestwick1_000403, Prestwick2_000403, Prestwick3_000403, Spectrum2_000573, Spectrum3_000611, Spectrum4_000128, Spectrum5_001500, Thyroxine, L- (8CI), bmse000923, D06RGG, Epitope ID:123889, Levothroid (*Sodiumsalt*), AC1L1L7K, BIDD:PXR0161, Levothroid (*Sodium salt*), SCHEMBL23098, BSPBio_000326, BSPBio_002142, KBioGR_000516, KBioSS_001556, MLS000028647, MLS002548901, DivK1c_006967, SPECTRUM1500774, SPBio_000386, SPBio_002265, BPBio1_000360, GTPL2635, DTXSID8023214, CTK2H7538, KBio1_001911, KBio2_001556, KBio2_004124, KBio2_006692, KBio3_001642, KS-00000HDI, MolPort-003-666-820, HMS1569A08, HMS1921I06, HMS2090P18, HMS2092K12, HMS2096A08, HMS2233J18, HMS3259M11, HMS3713A08, L-Thyroxine, >=98% (HPLC), Pharmakon1600-01500774, ZINC3830993, Tox21_112101, Tox21_302156, 3,3',5,5"-Tetraiodo-L-thyronine, BDBM50301375, CCG-38738, CT-230, GP9966, MFCD00002595, NSC757434, s2599, AKOS015905129, Tox21_112101_1, AC-7504, AM83594, AN-8921, CHM0030272, CS-1819, DB00451, NC00485, NSC-757434, SDCCGMLS-0066571.P001, 3,3'',5,5''-tetraiodo-L-thyronine, 3,5,3'',5''-tetraiodo-L-thyronine, NCGC00094852-03, NCGC00164336-02, NCGC00164336-03, NCGC00164336-05, NCGC00164336-06, NCGC00255368-01, AC-10465, AK-40208, AN-15421, BC630681, HY-18341, KB-53412, SAM002264651, SBI-0051608.P002, AB0010528, AB2000689, AX8015809, DB-006261, LS-158291, TR-031344, FT-0600821, LT00440967, ST24047479, C01829, D08125, J10324, AB00052176-08, AB00052176_09, AB00052176_10, 002T595, SR-05000001567, SR-01000759430-2, SR-05000001567-1, BRD-K30685142-001-05-5, BRD-K30685142-001-08-9, Thyroxine (T4), IRMM(R) certified Reference Material, L-Thyroxine, powder, BioReagent, suitable for cell culture, UNII-QR0BV3BRIA component XUIIKFGFIJCVMT-LBPRGKRZSA-N, Levothyroxine, United States Pharmacopeia (USP) Reference Standard, Levothyroxine, Pharmaceutical Secondary Standard; Certified Reference Material, Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, labeled with iodine-125, 1373931-44-2, 587-29-1, 587-30-4, 60833-83-2, 7200-84-2, 74-16-8, L-Thyroxine (T4) solution, 100 mug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, L-thyroxine zwitterion, CHEBI:58448, (2S)-2-ammonio-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate

ID: 83

InChIKey: YGULWPYYGQCFMP-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6420057
synonyms found at PubChem are:
56392-17-7, 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol 2,3-dihydroxysuccinate (2:1), Metoprolol-(+,-) (+)-tartrate salt, Prestwick_1009, AC1O4WIQ, SCHEMBL2051655, CHEMBL2062335, CTK8B7746, KS-00000XQB, MolPort-003-983-883, HMS1570C08, HMS3651I21, (A+/-)-Metoprolol (+)-tartrate, ANW-58344, AKOS016002993, RTR-019802, (.+-.)-tartaric acid; bis(metoprolol), KB-215768, 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)-propan-2-ol 2,3-dihydroxysuccinate (2:1), 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol 2,3-dihydroxysuccinate, 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate, Metoprolol tartrate solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

ID: 84

InChIKey: YKPUWZUDDOIDPM-SOFGYWHQSA-N
SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC

biological descriptors:

CFTR relevance: CFTR potentiator, increase in opening rate, decrease in closing rate

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"TC Hwang" "T Ai" "X Wang" "SG Bompadre" "S Hu" "M Li"

CID is 1548943
synonyms found at PubChem are:
Capsaicin, 404-86-4, Zostrix, CAPSAICINE, (E)-Capsaicin, Qutenza, Styptysat, Axsain, Isodecenoic acid vanillylamide, E-CAPSAICIN, trans-8-Methyl-N-vanillyl-6-nonenamide, NGX-4010, Capsaicin [USAN], Caswell No. 158, Transacin, (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-Capsaicin, NCI-C56564, NGX 4010, UNII-S07O44R1ZM, FEMA No. 3404, CCRIS 1588, CHEBI:3374, HSDB 954, C18H27NO3, Capsaicin (JAN/USP), 8-Methyl-N-Vanillyl-6-Nonenamide, 6-Nonenamide, 8-methyl-N-vanillyl-, (E)-, ZOSTRIX (TN), N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide, EINECS 206-969-8, NSC 56353, EPA Pesticide Chemical Code 070701, BRN 2816484, 8-Methyl-N-vanillyl-6-nonenamide, (E)-, (e)-n-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, CHEMBL294199, S07O44R1ZM, YKPUWZUDDOIDPM-SOFGYWHQSA-N, (6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (6E)-, NSC56353, Capsaicin [in oleoresin of capsicum], trans-Capsaicin-d3, NCGC00017337-02, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, (E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide, (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide, DSSTox_CID_241, 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (E)-, N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-, DSSTox_RID_75455, DSSTox_GSID_20241, Ausanil, (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide, [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, 6-Nonenamide, (E)-N-((4-hydroxy-3-methoxy-phenyl)methyl)-8-methyl, Capsaicin (in oleoresin of capsicum), (6E)-N-{[4-hydroxy-3-(methyloxy)phenyl]methyl}-8-methylnon-6-enamide, 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (6E)-, 8-Methyl-N-vanillyl-trans-6-nonenamide, CAPSAICIN, NATURAL, SR-05000001861, neurotoxic, Isodecenoate, Capsicin, Capsicine, Vanilloid, Mioton, N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, Adlea, TNP00277, Capsaicin Patch, (E)-N-[(4-Hydroxy-3-methoxyphenyl)-methyl]-8-methyl-6-nonenamide, ALGRX 4975, epsilon-capsaicin, Zostrix HP, Capsaicin,(S), Capsaicin(Qutenza), CAS-404-86-4, Prestwick_204, Capsaicin (Natural), depletes Substance P, 1217899-52-9, Citrus Aurantium 30%, Capsaicin [USP:INN], Citrus Aurantium Extract, 6-Nonenamide, (E)-, Prestwick2_000879, Prestwick3_000879, Spectrum5_000538, CITRUS AURANTIUM PE, D0U5CE, UPCMLD-DP092, AC1LU7K3, Bitter orange extract 30%, SCHEMBL8085, SCHEMBL8086, MR3H3, BSPBio_000957, BSPBio_001548, BSPBio_002917, MLS002154049, trans-8-Methyl-N-vanillylnon, Capsaicin, analytical standard, SPECTRUM1501128, Capsaicin, from natural source, AC1Q46B3, BPBio1_001053, GTPL2486, MEGxp0_001448, n-(4-hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide, (E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE, DTXSID9020241, UPCMLD-DP092:001, UPCMLD-DP092:002, BDBM20461, BDBM86537, CHEBI:94524, HMS501B16, MolPort-001-742-263, HMS1361N10, HMS1570P19, HMS1791N10, HMS1921H11, HMS1989N10, HMS2089N11, HMS2092D21, HMS2097P19, HMS2230O23, HMS3402N10, HMS3649N15, Pharmakon1600-01501128, 8-Methyl-N-vanillyl-6E-nonenamide, NGX-1998, NGX-3781, NGX-7325, NSC_2548, ZINC1530575, Tox21_110817, Tox21_200315, BBL027836, CC0144, CCG-39908, EI-125, LMFA08020085, MFCD00017259, N0C781, NSC-56353, NSC757844, STL372889, (E)-N-(4-Hydroxy-3-methoxybenzyl), (E)8-methyl-N-vanillyl-6-Nonenamide, AKOS007930159, CS-1518, DB06774, KS-5181, LS-2138, MCULE-8056866140, NSC-757844, RTC-030399, SDCCGMLS-0066678.P001, TQ-1018, Capsaicin, >=95%, from Capsicum sp., IDI1_000354, IDI1_034018, SMP2_000337, NCGC00017337-03, NCGC00017337-04, NCGC00017337-05, NCGC00017337-06, NCGC00017337-07, NCGC00017337-08, NCGC00017337-09, NCGC00017337-10, NCGC00017337-11, NCGC00017337-12, NCGC00017337-13, NCGC00017337-18, NCGC00090853-01, NCGC00090853-02, NCGC00090853-03, NCGC00090853-04, NCGC00090853-06, NCGC00090853-07, NCGC00090853-08, NCGC00090853-09, NCGC00090853-10, NCGC00090853-11, NCGC00090853-12, NCGC00257869-01, AC-10114, AJ-26667, AN-23437, CAS_404-86-4, CJ-23980, HY-10448, N735, SC-19636, SMR000718774, ST057183, Nonenamide, 8-methyl-N-vanillyl-, (E)-, SBI-0052593.P002, TC-030399, TL8002946, 4CH-016296, FT-0082538, M1149, N1667, (E)-8-Methyl-N-vanillyl-6-nonenamide(8cl), C06866, D00250, W-5044, AB00053098-11, AB00053098_12, Capsaicin, from Capsicum sp., >=50% (HPLC), 6-Nonenamide, 8-methyl-N-vanillyl-, (E)- (8CI), I01-2469, SR-05000001861-1, SR-05000001861-4, SR-05000001861-5, SR-05000001861-6, SR-05000001861-9, BRD-K37056290-001-01-1, BRD-K50590187-001-06-6, Capsaicin, certified reference material, TraceCERT(R), N-(3-Methoxy-4-hydroxybenzyl)-8-methyl-6-nonenamide, N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, Capsaicin (transdermal patch formulation, neuropathic pain), Capsaicin, European Pharmacopoeia (EP) Reference Standard, UNII-UW86K581WY component YKPUWZUDDOIDPM-SOFGYWHQSA-N, (6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide #, Capsaicin, United States Pharmacopeia (USP) Reference Standard, CAPSAICIN (2444-46-4 NONIVAMIDE (SYNTHETIC CAPSAICIN)), trans-N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material, Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8 -methyl-, (E)-, 912457-62-6

ID: 85

InChIKey: ZZIALNLLNHEQPJ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O

biological descriptors:

CFTR relevance: ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 5281707
synonyms found at PubChem are:
COUMESTROL, 479-13-0, Cumoestrol, Cumoesterol, Cumostrol, Coumesterol, 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one, 7,12-Dihydroxycoumestan, Cumestrol, 3,9-Dihydroxycoumestan, UNII-V7NW98OB34, NSC 22842, CCRIS 7311, NSC22842, 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 3,9-dihydroxy-, EINECS 207-525-6, BRN 0266702, CHEMBL30707, MLS000738006, CHEBI:3908, V7NW98OB34, ZZIALNLLNHEQPJ-UHFFFAOYSA-N, 3,9-Dihydroxy-6H-benzofuro(3,2-c)(1)benzopyran-6-one, 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihydroxy-, 3,9-dihydroxybenzofuro[3,2-c]chromen-6-one, A1-00298, SMR000059001, AC1NQYXV, DSSTox_CID_2399, D02DML, NCIMech_000078, DSSTox_RID_76572, DSSTox_GSID_22399, Oprea1_222511, SCHEMBL22012, 5-19-06-00405 (Beilstein Handbook Reference), MLS000069446, BIDD:ER0114, ZINC1219, DTXSID6022399, BDBM23451, CTK8F8799, MolPort-003-846-031, HMS2235B05, HMS3374A07, 6H-Benzofuro[3, 3,9-dihydroxy-, Coumestrol, >=95.0% (HPLC), HY-N2335, Tox21_200032, CCG-35536, CCG-36200, LMPK12090018, MFCD00016885, NSC-22842, AKOS028111776, AN-6463, API0002121, CS-6343, VZ31590, 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, delta-lactone (6CI), SMP2_000163, NCGC00018124-01, NCGC00018124-02, NCGC00018124-03, NCGC00018124-04, NCGC00018124-05, NCGC00018124-06, NCGC00023462-03, NCGC00023462-04, NCGC00257586-01, 4CN-2508, CAS-479-13-0, CC-25990, LS-35394, NCI60_001863, ZB000278, FT-0603177, ST50320052, V0359, C10205, S00280, US8552057, 3, 3,9-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one, 3,9-dihydroxy-[1]benzoxolo[3,2-c]chromen-6-one, 3,9-dihydroxy-6H-benzofuro[3,2-c]chromen-6-one, 3,9-dihydroxybenzo[d]chromeno[4,3-b]furan-6-one, A827386, C-16836, 3,9-Dihydroxy-benzo[4,5]furo[3,2-c]chromen-6-one, BRD-K97509413-001-01-8, 3,9-bis(oxidanyl)-[1]benzofuro[3,2-c]chromen-6-one, 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one #, 3,9-Dihydroxy-6H-benzofuro[3,2-c]-[1]benzopyran-6-one, 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihdyroxy-, 6H-Benzofuro[3,2-c][1]benzopyran-6-one,3,9-dihydroxy-, Coumestrol, BioReagent, suitable for fluorescence, >=97.5% (HPLC), 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic Acid |A-Lactone, 3-Benzofurancarboxylic acid,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone, 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone, 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, delta-lactone, 5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),2,4,6,11(16),12,14-heptaen-9-one

ID: 86

InChIKey: AAASNKNLMQBKFV-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC)OC)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 97142
synonyms found at PubChem are:
1244-78-6, 3-Hydroxy-3',4',5,7-tetramethoxyflavone, NSC102049, Quercetin 5,7,3',4'-tetramethyl ether, CHEBI:85124, 3',4',5,7-Tetramethylquercetin, NSC-102049, 2-(3,4-Dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-chromen-4-one, NSC 102049, Spectrum_000784, SpecPlus_000312, Spectrum2_000711, Spectrum3_001253, Spectrum4_001473, Spectrum5_000145, AC1L3XX0, BSPBio_002786, KBioGR_002045, KBioSS_001264, SPECTRUM300538, CHEMBL74675, DivK1c_006408, SPBio_000921, AC1Q6E16, SCHEMBL3135319, Flavone,4',5,7-tetramethoxy-, CTK8D4986, KBio1_001352, KBio2_001264, KBio2_003832, KBio2_006400, KBio3_002286, DTXSID40154319, ZINC1674568, CCG-38364, LMPK12112771, AKOS005145745, 3-Hydroxy-3',5,7-tetramethoxyflavone, SDCCGMLS-0066515.P001, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy- (9CI), NCGC00095598-01, NCGC00095598-02, NCGC00178472-01, NCI60_000056, 3-hydroxy-5,7,3',4'-tetramethoxyflavone, Quercetin tetramethyl(3',4',5,7) ether, RT-002389, 3-Hydroxy-3',4', 5,7-tetramethoxyflavone, 5-hydroxy-7,3',4',5'-tetramethoxyflavone, 3-Hydroxy-3/',4/',5,7-tetramethoxyflavone, A805642, SR-05000002615, SR-05000002615-1, BRD-K08825053-001-02-9, Flavone, 3-hydroxy-3',4',5,7-tetramethoxy- (8CI), 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxychromen-4-one, 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-chromen-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-3-oxidanyl-chromen-4-one, 4H-1-Benzopyran-4-one,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-, 2-(3,4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3, 4-dimethoxyphenyl)-3-hydroxy-5,7-dimethoxy-

ID: 87

InChIKey: AAEVYOVXGOFMJO-UHFFFAOYSA-N
SMILES: CC(C)NC1=NC(=NC(=N1)SC)NC(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4929
synonyms found at PubChem are:
prometryn, Prometryne, 7287-19-6, Gesagard, Prometrex, Selectin, Caparol, Uvon, Primatol Q, Mercasin, Mercazin, Merkazin, Polisin, Prometrin, Selektin, Sesagard, Gesagard 50, Gesagarde 50 Wp, Selectin 50, Caparol 80W, Promepin, Promethryn, Prometrene, Caswell No. 097, N,N'-Bis(1-methylethyl)-6-methylthio-1,3,5-triazine-2,4-diamine, UNII-1K20TB75IL, 1,3,5-Triazine-2,4-diamine, N,N'-bis(1-methylethyl)-6-(methylthio)-, Prometryn [ANSI:BSI:ISO], A 1114, NSC 163049, G 34161, N2,N4-Diisopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine, Prometryne [ISO-French:JMAF], 2,4-Bis(isopropylamino)-6-methylmercapto-s-triazine, 2-Methylmercapto-4,6-bis(isopropylamino)-s-triazine, HSDB 4060, s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)-, EINECS 230-711-3, 2-Methylthio-4,6-bis(isopropylamino)-s-triazine, G-34161, EPA Pesticide Chemical Code 080805, 2,4-Bis(isopropylamino)-6-(methylthio)-s-triazine, 2-(Methylthio)-4,6-bis(isopropylamino)-s-triazine, BRN 0613575, 2,4-Bis(isopropylamino)-6-methylthio-1,3,5-triazine, AI3-60366, 1K20TB75IL, CHEBI:26276, AAEVYOVXGOFMJO-UHFFFAOYSA-N, 2,4-Bis(isopropylamino)-6-methylthio-s-triazine, s-Triazine, 4,6-bis(isopropylamino)-2-methylmercapto-, 2,4-Bis(propylamino)-6-methylthio-1,3,5-triazin [German], N,N-Di-isopropyl-6-methylthio-1,3,5-triazine-2,4-diamine, N,N'-diisopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine, N,N'-Diisopropyl-6-methylthio-1,3,5-triazine-2,4-diyldiamine, N2,N4-Di-isopropyl-6-methylthio-1,3,5-triazine-2,4-diamine, 6-(methylsulfanyl)-N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, DSSTox_CID_4272, N,N'-Bis(1-methylethyl)-6-methyl-thio-1,3,5-triazine-2,4-diamine, DSSTox_RID_77350, DSSTox_GSID_24272, Prometryn, analytical standard, W-104476, 2,4-Bis(isopropylamino)-6-(methylmercapto)-s-triazine, 2-(Methylmercapto)-4,6-bis(isopropylamino)-s-triazine, 6-methylsulfanyl-2-N,4-N-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, CAS-7287-19-6, Promethryne, Cotton-Pro, Prometryn solution, Caparol 4L, Spectrum_001837, SpecPlus_000438, Cotton-Pro (Salt/Mix), Spectrum2_001887, Spectrum3_000829, Spectrum4_000669, Spectrum5_001970, Caparol 4L (Salt/Mix), AC1Q7E1J, SCHEMBL7622, BSPBio_002357, KBioGR_001077, KBioSS_002342, SPECTRUM330037, 2,4-Bis(propylamino)-6-methylthio-1,3,5-triazin, MLS002695921, DivK1c_006534, SPBio_001794, AC1L1J96, 4,6-Bis(isopropylamino)-2-(methylthio)-1,3,5-triazine, CHEMBL1880257, DTXSID4024272, AAEVYOVXGOFMJO-UHFFFAOYSA-, KBio1_001478, KBio2_002339, KBio2_004907, KBio2_007475, KBio3_001857, MolPort-002-043-491, HMS3089A14, s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)- (8CI), n,n'-diisopropyl-6-(methylsulfanyl)-1,3,5-triazin-2,4-diamin, ZINC1635499, Tox21_202338, Tox21_300807, CCG-39425, NSC163049, STK687533, AKOS005206531, MCULE-8449557554, NSC-163049, Prometryn 10 microg/mL in Cyclohexane, Prometryn 10 microg/mL in Acetonitrile, NCGC00094530-01, NCGC00094530-02, NCGC00094530-03, NCGC00094530-04, NCGC00094530-05, NCGC00094530-06, NCGC00254711-01, NCGC00259887-01, Prometryn 100 microg/mL in Acetonitrile, AJ-28509, CC-33942, CJ-26336, O632, SMR000778056, KB-258544, LS-155138, TR-023735, FT-0630367, Prometryn, PESTANAL(R), analytical standard, Bis(isopropylamino)-6-(methylthio)-S-triazine, C18542, WLN: T6N CN ENJ BS1 DMY1&1 FMY1&1, 2,4-Bis(isopropylamino)-6-(methylthio)triazine, 287P196, A837648, C-14516, s-Triazine,4-bis(isopropylamino)-6-(methylthio)-, 2-methylthio-4,6-bis(isopropylamino)-1,3,5-triazine, 2-Methylthio-4,6-bis(isopropylamino)-1,3,5triazine, BRD-K32582260-001-02-5, s-Triazine,6-bis(isopropylamino)-2-(methylmercapto)-, 2,4-Bis(isopropylamino)-6-(methylthio)-1,3,5-triazine, 2,4-Bis-(isopropylamino)-6-methylthio-1,3,5-triazine, 2-Methylthio-4,6-bis(isopropyl amino)-1,3,5-triazine, S-Triazine, 2,4-bis(isopropylamino)-6-methylmercapto-, A3964/0168949, s-Triazine, 4,6-bis(isopropylamino)-2-(methylmercapto)-, 2,4-Diamine-N,N'-bis(1-methylethyl)-6-(methylthio)triazine, 6-(methylthio)-N2,N4-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, 6-methylsulfanyl-N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, N,N'-Diisopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine, 1,5-Triazine-2,4-diamine, N,N'-bis(1-methylethyl)-6-(methylthio)-, 6-methylsulfanyl-N2,N4-di(propan-2-yl)-1,3,5-triazine-2,4-diamine, 1,3,5-Triazine-2,4-diamine, N,N'-bis(1-methylethyl)-6-(methylthio)- (9CI), Prometryn solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 83653-07-0, InChI=1/C10H19N5S/c1-6(2)11-8-13-9(12-7(3)4)15-10(14-8)16-5/h6-7H,1-5H3,(H2,11,12,13,14,15)

ID: 88

InChIKey: AAFNEINEQRQMTF-LREBCSMRSA-N
SMILES: CC1(CCCC(N1C)(C)C)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 120729
synonyms found at PubChem are:
Pempidine tartrate, Sinapleg, Synapleg, Pempidine bitartrate, Pempidine hydrogen tartrate, UNII-THI82M7N4M, 546-48-5, Pempidina tartrato [Italian], EINECS 208-902-8, THI82M7N4M, 1,2,2,6,6-Pentamethylpiperidine tartrate, Piperidine, 1,2,2,6,6-pentamethyl-, tartrate (1:1), Pempidina tartrato, C10H21N.C4H6O6, AC1L3RDA, AC1Q5R2R, Lopac0_000939, SCHEMBL933339, API0015931, Piperidine, 1,2,2,6,6-pentamethyl-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1), NCGC00094245-01, LS-115858, EU-0100939, P 5114, SR-01000076249, SR-01000076249-1, 1,2,2,6,6-pentamethylpiperidine (2R,3R)-2,3-dihydroxysuccinate, (2R,3R)-2,3-dihydroxybutanedioic acid; 1,2,2,6,6-pentamethylpiperidine, (2R,3R)-2,3-dihydroxybutanedioic acid;1,2,2,6,6-pentamethylpiperidine, Piperidine, 1,2,2,6,6-pentamethyl-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (9CI)

ID: 89

InChIKey: AAKJUGSASOCUFQ-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C2=C(C3=C1OC(C=C3)(C)C)OC(=O)C(=C2O)C4=CC=C(C=C4)O)OC)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54676535
synonyms found at PubChem are:
Scandenin, CHEMBL1603825, KBio1_001385, AC1LCPJW, Spectrum_000746, SpecPlus_000345, Spectrum2_001906, Spectrum3_001312, Spectrum4_001469, Spectrum5_000117, BSPBio_003003, KBioGR_002017, KBioSS_001226, SPECTRUM300348, DivK1c_006441, SPBio_001872, SCHEMBL12062082, CHEBI:93435, KBio2_001226, KBio2_003794, KBio2_006362, KBio3_002223, AAKJUGSASOCUFQ-UHFFFAOYSA-N, BDBM50442909, CCG-38477, LMPK12160022, SDCCGMLS-0066849.P001, NCGC00095595-01, NCGC00095595-02, NCGC00178349-01, 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 4-hydroxy-3-(4-hydroxyphenyl)-5-methoxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-, 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 4-hydroxy-3-(p-hydroxyphenyl)-5-methoxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-, BRD-K81847782-001-02-1, 2-hydroxy-3-(4-hydroxyphenyl)-5-methoxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one, 4-Hydroxy-3-(4-hydroxyphenyl)-5-methoxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-2H,8H-pyrano[2,3-f]chromen-2-one #, 5084-00-4

ID: 90

InChIKey: AAWZDTNXLSGCEK-LNVDRNJUSA-N
SMILES: C1[C@H](C([C@@H](CC1(C(=O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6508
synonyms found at PubChem are:
quinic acid, D-(-)-Quinic acid, 77-95-2, (-)-quinic acid, Chinic acid, Kinic acid, Chinasaure, quinate, D-QUINIC ACID, L-Quinic acid, UNII-058C04BGYI, D(-)-Quinic acid, D-(-)-QuinicAcid, L-Quinate, NSC1115, (3r,5r)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid, SpecPlus_000419, NSC59258, EINECS 201-072-8, NSC 59258, (-)-1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid, DivK1c_006515, 058C04BGYI, CHEBI:17521, (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid, AAWZDTNXLSGCEK-WYWMIBKRSA-N, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1R-(1-alpha,3-alpha,4-alpha,5-beta))-, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1R-(1alpha,3alpha,4alpha,5beta))-, SDCCGMLS-0066613.P001, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (-)-, 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid (1R-(1alpha,3alpha,4alpha,5beta), Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1theta-(1alpha,3alpha,4alpha,5beta))-, 1L-1(OH),3,4/5-Tetrahydroxycyclohexanecarboxylic acid, (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid, Cyclohexanecarboxylicacid, 1,3,4,5-tetrahydroxy-, (1a,3R,4a,5R)-, D-(-)-Kinic Acid, D-(-)-Chinic Acid, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1.alpha.,3R,4.alpha.,5R)-, 36413-60-2, Quinicacid, 1L-1(OH),3,4/5-Tetrahydroxycyclohexanecarboxylate, Rel-Quinic Acid, 4gui, 4iuo, C7H12O6, (-)Quinic acid, QIC, PubChem8105, D-(-)-Quinic-acid, Spectrum_001413, AC1L1MOP, AC1Q5TBL, Spectrum2_001790, Spectrum3_001349, Spectrum4_001867, Spectrum5_000434, bmse000306, AC1Q59HD, SCHEMBL39556, BSPBio_003137, KBioGR_002336, KBioSS_001893, SPECTRUM310018, KSC645E2N, MLS002207201, SPBio_001719, CHEMBL465398, MEGxp0_001735, SCHEMBL1286207, SCHEMBL1286208, SCHEMBL7923331, D-(-)-Quinic acid, 98%, ACon1_001963, CTK5E5226, KBio1_001459, KBio2_001893, KBio2_004461, KBio2_007029, KBio3_002357, D-(−)-Quinic acid, AAWZDTNXLSGCEK-LNVDRNJUSA-N, MolPort-001-742-493, MolPort-028-750-726, KS-000014QH, NSC-1115, ZINC1764753, ANW-43810, BBL033519, CCG-38438, MFCD00003864, NSC-59258, STK801928, (-) Quinic acid, analytical standard, AKOS005622501, ZINC100009542, ZINC100076909, MCULE-1240547998, MCULE-2526162099, RTR-032721, NCGC00178246-01, NCGC00178246-02, BP-12304, LS-56752, SC-06773, SMR001306762, AB1003944, FT-0624343, N1691, Q0009, Z7206, 1,3,4,5Tetrahydroxycyclohexanecarboxylic acid, C00296, D-(-)-Quinic acid, purum, >=98.0% (T), 003D864, W-203791, 883DE888-EC82-454C-B69C-8B1F9AC6DAA9, Z2767312005, (1R,3R,4R,5R)-(-)-Tetrahydroxycyclohexanecarboxylic acid, (3R,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid, (3R,5R)-1,3,4,5-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,3beta,4alpha,5alpha-Tetrahydroxycyclohexane-1alpha-carboxylic acid, Quinic acid, United States Pharmacopeia (USP) Reference Standard, Quinic Acid, Pharmaceutical Secondary Standard; Certified Reference Material, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3R,4alpha,5R)-, Cyclohexanecarboxylic acid,3,4,5-tetrahydroxy-, (1.alpha.,3.alpha.,4.alpha.,5.beta.)-, 35949-55-4, Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1.alpha., 3.alpha.,4.alpha.,5.beta.)-

ID: 91

InChIKey: ABBQHOQBGMUPJH-UHFFFAOYSA-M
SMILES: C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5900
synonyms found at PubChem are:
Sodium salicylate, 54-21-7, Sodium 2-hydroxybenzoate, Salsonin, Clin, Enterosalicyl, Enterosalil, Entrosalyl, Glutosalyl, Kerasalicyl, Magsalyl, Alysine, Aroall, Kerosal, Nadisal, Salisod, Idocyl novum, Neo-salicyl, Diuretin, Parbocyl-rev, Benzoic acid, 2-hydroxy-, monosodium salt, Monosodium salicylate, Sodium o-hydroxybenzoate, NaSal, UNII-WIQ1H85SYP, Natrium salicylat [German], Salicylic acid, sodium salt, Monosodium 2-hydroxybenzoate, Salicylic acid Na+, Salicylic Acid, Na, CCRIS 6715, o-Hydroxybenzoic acid, sodium salt, EINECS 200-198-0, o-Hydroxybenzoic acid monosodium salt, Salicylic acid sodium salt, WIQ1H85SYP, 2-Hydroxybenzoic acid monosodium salt, NSC 202167, CHEBI:9180, Salicylic acid, monosodium salt, IN1086, sodium;2-hydroxybenzoate, 2-HYDROXYBENZOIC ACID, MONOSODIUM SALT, Benzoic acid, 2-hydroxy-, sodium salt (1:1), Natrum salicylicum, Diuratin, sodiumsalicylate, Sodium salicylate [USP:JAN], Monosodium salicylatn, Salicylsaeure-Na-salz, Sodium o-hydroxybenzoatn, Sodium 2-hydroxybenzoatn, Sodium salicylate, 99%, Spectrum2_001945, Spectrum3_000900, Spectrum4_000995, Spectrum5_001120, DSSTox_CID_1708, potassium o-hydroxybenzoate, Salicylic acid sodium saln, NPFAPI-03, EC 200-198-0, SCHEMBL4603, Monosodium 2-hydroxybenzoatn, DSSTox_RID_76287, DSSTox_GSID_21708, KBioGR_001429, 90218-97-6, KSC269G8P, SPECTRUM1500533, SPBio_002009, CHEMBL447868, DTXSID5021708, Sodium salicylate (JP17/USP), CTK1G9387, HY-B0167A, KBio3_001820, ABBQHOQBGMUPJH-UHFFFAOYSA-M, MolPort-002-324-170, Sodium salicylate, 99% 500g, HMS1920P16, HMS2092G17, KS-00000X7W, Sodium salicylate, p.a., 99.5%, Tox21_200411, [http://ChEMBL = 447868, 2-Hydroxy Benzoic acid, sodium salt, CCG-39474, MFCD00002440, RTA-01003, AKOS003051698, AKOS005766021, CS-2008, CAS-54-21-7, NCGC00094780-01, NCGC00094780-02, NCGC00257965-01, AK307396, AN-24416, Benzoic acid, 2-hydroxy-, monosodium salt, coupled with 4-amino-1-naphthalenesulfonic acid and diazotized 2-(4-aminophenyl)-1H-benzimidazol-5-amine, sodium salt, H365, KB-80645, AB1009427, FT-0631235, 1875-EP2269977A2, 1875-EP2280012A2, 1875-EP2305250A1, 1875-EP2308833A2, C07587, D00566, Sodium salicylate, ReagentPlus(R), >=99.5%, Sodium salicylate, SAJ first grade, >=99.5%, Sodium salicylate, tested according to Ph.Eur., 66873-EP2275420A1, 66873-EP2280008A2, 66873-EP2281823A2, 66873-EP2295406A1, 66873-EP2298731A1, 66873-EP2298764A1, 66873-EP2298765A1, 66873-EP2298772A1, 66873-EP2308510A1, 66873-EP2308839A1, 66873-EP2371811A2, Sodium salicylate, SAJ special grade, >=99.5%, Sodium salicylate, Vetec(TM) reagent grade, 99%, I14-7511, Sodium salicylate, meets USP testing specifications, Sodium salicylate, puriss. p.a., >=99.5% (NT), 2-Hydroxybenzoic acid sodium salt; Salicylic acid sodium salt, Sodium salicylate, European Pharmacopoeia (EP) Reference Standard, Sodium salicylate, United States Pharmacopeia (USP) Reference Standard, 18495-69-7, 94413-51-1, Sodium salicylate, puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance), salicylate de sodium, SCHEMBL8922293, HMS500P03

ID: 92

InChIKey: ABGZFAWHPVNBOG-UHFFFAOYSA-N
SMILES: CC1=C(C(=C(C(=N1)C)C(=O)OC)C2=CC=C(C=C2)C(C)C)C(=O)OC

biological descriptors:

reference list:

"VS Gopinath" "RK Guy" "AS Verkman" "H Yang" "AA Shelat" "A Taddei" "C Folli" "K Du" "T Ma" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 19232492
synonyms found at PubChem are:
AKOS003007998

ID: 93

InChIKey: ABJKIHHNDMEBNA-UHFFFAOYSA-N
SMILES: CC1=COC2=CC=CC=C2C1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66569
synonyms found at PubChem are:
Methylchromone, 3-Methylchromone, Crodimyl, Spasmocromona, Cromonalgina, Diacromone, Tricromyl, 85-90-5, Chromone, 3-methyl-, 3-methyl-4H-chromen-4-one, 3-Methyl-4(4H)-chromenone, 3-Methyl-4(H)-chromen-4-one, 3-Methyl-4H-1-benzopyran-4-one, Metilcromone [DCIT], 4H-1-Benzopyran-4-one, 3-methyl-, UNII-KJ0091KAAH, 3-Methyl-gamma-benzopyrone, Methylchromone [INN:BAN], 3-Metil-cromone [Italian], Metilcromona [INN-Spanish], NSC 76095, Methylchromonum [INN-Latin], EINECS 201-641-0, BRN 0117920, KJ0091KAAH, 3-Methyl-.gamma.-benzopyrone, C10H8O2, Methylchromonum, Metilcromona, Metilcromone, 3-Metil-cromone, 3-methylchromen-4-one, Spectrum_001209, SpecPlus_000745, Spectrum5_001726, DSSTox_CID_31634, DSSTox_RID_97518, DSSTox_GSID_57845, SCHEMBL25934, KBioSS_001689, 5-17-10-00164 (Beilstein Handbook Reference), DivK1c_006841, Chromone, 3-methyl- (8CI), AC1L25O0, ZINC1707, CHEMBL2105215, DTXSID4057845, CTK5F5944, KBio1_001785, KBio2_001689, KBio2_004257, KBio2_006825, ABJKIHHNDMEBNA-UHFFFAOYSA-N, CHEBI:134790, MolPort-002-893-685, NSC76095, 4H-1-Benzopyran-4-one,3-methyl-, Tox21_113786, NSC-76095, STL356197, AKOS016356352, FCH1119537, MCULE-4780438132, CAS-85-90-5, NCGC00253661-01, CC-15616, LS-39788, ZB000395, DB-056888, FT-0603297, C-03987, SR-01000944928, SR-01000944928-1, Urea,5-dihydro-1H-imidazol-2-yl)phenyl]-N'-4-[[[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]amino]carbonyl]amino]phenyl]-, dihydrochloride

ID: 94

InChIKey: ABTNETSDXZBJTE-WLHGVMLRSA-N
SMILES: COC(=O)N1CCN(C(C1)CN2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.C(=C/C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6442840
synonyms found at PubChem are:
GR 89696 fumarate, 126766-32-3, GR-89696 fumarate, GR 89696, GR 89696 fumarate salt, GR 85571, 4-([3,4-DICHLOROPHENYL]ACETYL)-3-(1-PYRROLIDINYLMETHYL)-1-PIPERAZINECARBOXYLIC ACID METHYL ESTER FUMARATE, 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate salt, SMR000466287, SR-01000075500, GR 103545, 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate, AC1O5XZT, 1-((3,4-Dichlorophenyl)acetyl)-4-acetyl-2-(1-pyrrolidinylmethyl)piperazine, Methyl 4-((3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylate fumarate, MLS000758305, MLS001424140, SCHEMBL1282478, SCHEMBL1282479, gr89696, CHEMBL1256865, GR 89696 fumarate salt, solid, MolPort-003-941-452, HMS2051L20, HMS3261D06, HMS3267N18, Tox21_500572, MFCD00274044, AKOS024456628, 4-[(3,4-Dichlorophenyl)acetyl]-3-, CCG-101060, CCG-221876, LP00572, NC00310, NCGC00093956-01, NCGC00261257-01, 1-Piperazinecarboxylic acid, 4-((3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl ester, (E)-2-butenedioate (1:1), CPD000466287, SAM001247087, RT-013118, EU-0100572, G-133, J-005434, SR-01000075500-1, SR-01000075500-3, (1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate, (E)-but-2-enedioic acid; methyl 4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate, methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate

ID: 95

InChIKey: ABTXGJFUQRCPNH-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66068
synonyms found at PubChem are:
procainamide hydrochloride, Procainamide Hcl, 614-39-1, Pronestyl, Procanbid, Procapan, Procan, Procainhydrochlorid, Procan SR, Procainii chloridum, Promide hydrochloride, Procapan hydrochloride, Novocamid hydrochloride, Procaini hydrochloridum, Procamide hydrochloride, Procardyl hydrochloride, Procan-SR hydrochloride, Procaine amide hydrochloride, Supicane amide hydrochloride, Procainamide (hydrochloride), UNII-SI4064O0LX, 4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride, CCRIS 7143, 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, EINECS 210-381-7, Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-, monohydrochloride, MLS000069436, CHEBI:8429, SI4064O0LX, 7699-39-0, 4-Aminobenzoesaeure-2-diethylaminoethylester hydrochlorid, p-Amino-N-(2-(diethylamino)ethyl)benzamide hydrochloride, 4-Amino-N-(2-(diethylamino)ethyl)benzamide hydrochloride, 4-Amino-N-(2-(diethylamino)ethyl)benzamide monohydrochloride, p-Amino-N-(2-(diethylamino)ethyl)benzamide monohydrochloride, SMR000059079, Procanbid (TN), Pronestyl (TN), Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-, monohydrochloride, Benzamide, p-amino-N-(2-(diethylamino)ethyl)-, hydrochloride, SR-01000000022, CAS-614-39-1, (4-aminophenyl)-N-[2-(diethylamino)ethyl]carboxamide, chloride, PROCAINAMIDEHYDROCHLORIDE, Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-, hydrochloride (1:1), Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1), 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride, Procainamide hydrochloride [USP:JAN], Procainamide hydrochloride [USAN:JAN], Procan SR (TN), Pronestyl hydrochloride, Procainamide HCL USP, PubChem15966, Opera_ID_1543, CHEMBL605, Epitope ID:140114, AC1L24JW, C13H22ClN3O, DSSTox_CID_29382, DSSTox_RID_83497, DSSTox_GSID_49422, SCHEMBL40758, MLS001148635, 51-06-9 (Parent), SPECTRUM1500503, DTXSID2049422, CTK6E8331, ABTXGJFUQRCPNH-UHFFFAOYSA-N, MolPort-002-319-710, HMS1569C15, HMS1920L04, Pharmakon1600-01500503, ACT08464, BCP28404, HY-A0084, Tox21_202855, Tox21_500995, CCG-39233, MFCD00012998, NSC757279, s4294, SBB001067, AKOS008056264, AC-7552, AN-8900, EBD3071181, KS-5258, LP00995, MCULE-9726613752, NC00535, NE10724, NSC-757279, Procainamide hydrochloride (JP17/USP), VA11587, NCGC00094291-01, NCGC00094291-02, NCGC00094291-03, NCGC00094291-04, NCGC00094291-05, NCGC00260401-01, NCGC00261680-01, BC209722, CPD000059079, LS-25497, M850, SAM002554928, KB-304279, TR-034892, 4-Aminobenzoic acid 2-diethylaminoethylamide, EU-0100995, FT-0603493, ST50319808, VU0239777-5, BIM-0050968.0001, D00477, P 9391, 4-amino-N-(2-diethylamino-ethyl)-benzamide HCl, I01-2626, Procainamide hydrochloride, purum, >=98.0% (AT), SR-01000000022-2, SR-01000000022-6, W-105155, F0850-6742, 4-amino-N-[2-(diethylamino)ethyl]-Benzamide hydrochloride, Procainamide hydrochloride, European Pharmacopoeia (EP) Reference Standard, Procainamide hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Procainamide hydrochloride, United States Pharmacopeia (USP) Reference Standard, AC1LCWA9, AKOS026749765, 4-amino-N-(2-diethylaminoethyl)benzamide; hydron; chloride

ID: 96

InChIKey: ABUBCBFUQXIEAU-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=CC(=O)OC2=C1OC)C3=CC=CC=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4412068
synonyms found at PubChem are:
Kuhlmannin, 6-Hydroxy-7,8-dimethoxy-4-phenylcoumarin, 20972-79-6, SPBio_002203, Spectrum_000560, SpecPlus_000638, AC1N9KHM, Spectrum2_001992, Spectrum3_001261, Spectrum4_001594, Spectrum5_000308, BSPBio_002822, KBioGR_002208, KBioSS_001040, SPECTRUM240862, DivK1c_006734, CHEMBL1568181, SCHEMBL12062100, KBio1_001678, KBio2_001040, KBio2_003608, KBio2_006176, KBio3_002322, CHEBI:108605, CCG-39477, LMPK12100011, SDCCGMLS-0066486.P001, NCGC00095925-01, NCGC00095925-02, NCGC00178451-01, 6-hydroxy-7,8-dimethoxy-4-phenylchromen-2-one, SR-05000002551, SR-05000002551-1, 6-hydroxy-7,8-dimethoxy-4-phenyl-2H-chromen-2-one, BRD-K18149487-001-02-8

ID: 97

InChIKey: ACGUYXCXAPNIKK-UHFFFAOYSA-N
SMILES: C1=C(C(=C(C(=C1Cl)Cl)CC2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3598
synonyms found at PubChem are:
hexachlorophene, 70-30-4, Hexachlorofen, Hexachlorophen, Nabac, Almederm, Exofene, Fostril, pHisoHex, Gamophene, Hexophene, Steraskin, Tersaseptic, Acigena, Dermadex, Distodin, Gamophen, Hexabalm, Hexafen, Phisodan, Septisol, Septofen, Surofene, Hexide, Steral, Turgex, Germa-Medica, Surgi-Cen, Surgi-Cin, Cotofilm, Ritosept, Hexosan, Fomac, Fesia-sin, Soy-dome, Ster-zac, Neosept V, G-Eleven, Hexachlorophane, Hexaclorofeno, Hexascrub, Bilevon, Hexachlorophenum, Phiso-Scrub, Septi-Soft, Hexa-Germ, TRICHLOROPHENE, Armohex, Compound G-11, Nabac 25 ec, Staphene O, Solu-Heks, 6,6'-Methylenebis(2,4,5-trichlorophenol), Pre-Op, Esaclorofene, Trisophen, Bivelon, E-Z Scrub, G-II, Hexaphene-LV, Hilo Flea Powder, At-17, Rcra waste number U132, Enditch Pet Shampoo, Eleven, Fascol, 2,2'-Methylenebis(3,4,6-trichlorophenol), Esaclorofene [DCIT], Hexachlorofen [Czech], Hilo Cat Flea Powder, Scrubteam Surgical Spongebrush, PRE-OP II, AT-7, Pedigree Dog Shampoo Bar, 2,2'-methanediylbis(3,4,6-trichlorophenol), Bis(2-hydroxy-3,5,6-trichlorophenyl)methane, Bis(3,5,6-trichloro-2-hydroxyphenyl)methane, Isobac, NCI-C02653, G-11, Hexaclorofeno [INN-Spanish], Caswell No. 566, Hexachlorophenum [INN-Latin], Blockade Anti Bacterial Finish, Hexachlorophene [INN], AT 7, Fo stril, UNII-IWW5FV6NK2, 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane, 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane, B 32 (VAN), B & b Flea Kontroller for Dogs Only, C13H6Cl6O2, CCRIS 331, Phenol, 2,2'-methylenebis[3,4,6-trichloro-, 2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane, HSDB 224, MLS000028433, SMR000058356, Hexachlorophene, Pharma, Brevity Blue Liquid Sanitizing Scouring Cream, En-Viron D Concentrated Phenolic Disinfectant, EINECS 200-733-8, NSC 49115, UN2875, IWW5FV6NK2, Hexachlorophene [UN2875] [Poison], Isobac 20, Phenol, 2,2'-methylenebis(3,4,6-trichloro)-, Brevity Blue Liquid Bacteriostatic Scouring Cream, RCRA waste no. U132, EPA Pesticide Chemical Code 044901, Bis-2,3,5-trichloro-6-hydroxyfenylmethan [Czech], Hexachlorophene (USP/INN), BRN 2064407, B 32, Bis-2,3,5-trichloro-6-hydroxyfenylmethan, AI3-02372, MLS002152906, CHEBI:5693, Thera-Groom Pet Shampoo for Dogs for Veterinary Use Only, 2,2'-Methylenebis[3,4,6-trichlorophenol], 2,2'-Methylene bis(3,4,6-trichlorophenol), Bis(3,5,6-trichloro-2-hydroxyphenyl)-methane, Phenol, 2,2'-methylenebis(3,4,6-trichloro-, ACGUYXCXAPNIKK-UHFFFAOYSA-N, Methane, bis(2,3,5-trichloro-6-hydroxyphenyl), KUC106447N, Methane, bis(2,3,5-trichloro-6-hydroxyphenyl)-, Methylenebis(3,4,6-trichlorophenol), KSC-19-051, NCGC00091195-04, Bis-2,3,5-trichlor-6-hydroxyfenylmethan, DSSTox_CID_690, 2,4,6-trichlorophenol], 2,5,6-trichlorophenol), M0219, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol, Bis(2,3,5-trichloro-6-hydroxyphenyl)methane, Bis(2,3,5-tric hloro-6-hydroxyphenyl)methane, DSSTox_RID_75738, DSSTox_GSID_20690, B32, 3,3',5,5',6,6'-Hexachloro-2,2'-dihydroxydiphenylmethane, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxy-phenyl)methyl]phenol, Bis-2,5-trichlor-6-hydroxyfenylmethan, CAS-70-30-4, Methane,3,5-trichloro-6-hydroxyphenyl), Bis(2-hydroxy-3,6-trichlorophenyl)methane, Bis(3,6-trichloro-2-hydroxyphenyl)methane, Phenol,2'-methylenebis[3,4,6-trichloro-, Phenol,2'-methylenebis[3,5,6-trichloro-, WLN: QR BG DG EG F1R BQ CG EG FG, 2,3',5,5',6,6'-hexachlorodiphenylmethane, 2,5,6,3',5',6'-hexachlorodiphenylmethane, SR-01000721924, 2,3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane, 3,4,6-trichloro-2-[(3,5,6-trichloro-2-hydroxyphenyl)methyl]phenol, Hexachlorophenone, Hexachlorophene [USP:INN:BAN], Phisohex(TN), Almederm (TN), Gamophen (TN), Phisohex (TN), Septisol (TN), Surofene (TN), Acigena (TN), Bilevon (TN), Exofene (TN), Fostril (TN), Hexosan (TN), Germa-Medica (TN), Spectrum_000867, Opera_ID_504, AC1L1GAE, Spectrum2_001105, Spectrum3_000450, Spectrum4_000573, Spectrum5_000792, CHEMBL496, D0ZX2G, GERMA-MEDICA "MG", GERMA-MEDICA (MG), cid_3598, REGID_for_CID_3598, SCHEMBL15579, BSPBio_002100, KBioGR_001006, KBioSS_001347, MLS001148404, BIDD:ER0608, BIDD:GT0722, DivK1c_000630, SPECTRUM1500328, SPBio_001210, AT7 (TN), DTXSID6020690, AT17 (TN), BDBM31712, CTK9A1850, HMS501P12, KBio1_000630, KBio2_001347, KBio2_003915, KBio2_006483, KBio3_001320, NSC9887, MolPort-001-785-865, NINDS_000630, HMS1920D07, HMS2091J13, HMS3259C19, HMS3715P21, KUC112427N, Pharmakon1600-01500328, NSC-9887, NSC49115, ZINC1530968, Tox21_111099, Tox21_201350, Tox21_302741, 0895AC, CCG-39768, G-11 (TN), MFCD00002171, NSC-49115, NSC757055, s4632, SBB058855, STK377478, AKOS005449243, Tox21_111099_1, API0002904, CS-3866, DB00756, LS-1597, MCULE-3028228047, NC00512, NSC-757055, UN 2875, IDI1_000630, NCGC00091195-01, NCGC00091195-02, NCGC00091195-03, NCGC00091195-05, NCGC00091195-06, NCGC00091195-07, NCGC00091195-08, NCGC00256580-01, NCGC00258902-01, AJ-26716, AN-41934, AS-10068, BP-30177, CPD000058356, HY-12637, SAM002554903, SC-51022, 2,2-Methylenebis(3,4,6-Trichlorophenol), KSC-285-117-1, SBI-0051403.P003, KB-247348, TR-023301, FT-0626955, ST24029562, ST50880633, 2,2-Methylene-bis-[3,4,6-trichlorophenol], 2,2 -Methylene-bis-[3,4,6-trichlorophenol], 2,2'-Methylene-bis-[3,4,6-trichlorophenol], Bis-(2-hydroxy-3,5,6-trichlorophenyl)methane, C08039, D00859, MLS-0072923.0001, AB00052010_17, Bis[3,4,6-trichlorophenol], 2,2'-methylene-, Hexachlorophene, PESTANAL(R), analytical standard, SR-01000721924-2, SR-01000721924-5, SR-01000721924-6, BRD-K99792991-001-02-6, BRD-K99792991-001-18-2, I14-19538, Hexachlorophene Solution, 5000 microg/mL in Dichloromethane, Hexachlorophene, United States Pharmacopeia (USP) Reference Standard, 1195388-85-2, 139411-96-4, 8054-98-6

ID: 98

InChIKey: ACPOUJIDANTYHO-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 8515
synonyms found at PubChem are:
1,9-Pyrazoloanthrone, 129-56-6, SP600125, Pyrazolanthrone, Dibenzo[cd,g]indazol-6(2H)-one, Pyrazoleanthrone, SP 600125, Anthra[1,9-cd]pyrazol-6(2H)-one, Anthra-1,9-pyrazol-6-none, C.I. 70300, SP-600125, 2H-Dibenzo[cd,g]indazol-6-one, JNK Inhibitor II, SAPK Inhibitor II, NSC 75890, UNII-1TW30Y2766, ANTHRA(1,9-cd)PYRAZOL-6(2H)-ONE, EINECS 204-955-6, BRN 0746890, CHEMBL7064, MLS002693964, CHEBI:90695, ACPOUJIDANTYHO-UHFFFAOYSA-N, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, InSolution™ JNK Inhibitor II, 1TW30Y2766, NCGC00015958-03, 14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one, SMR000015440, SR-01000075840, 1pmv, 2zmd, SAPK Inhibitor I, NSC75890, NSC-75890, 1 9-pyrazoleanthrone, Kinome_3844, Tocris-1496, AC1Q6DQN, BiomolKI_000068, timtec-bb sbb000595, Lopac-S-5567, BiomolKI2_000072, D00JXM, D02PVB, AC1L1R5Y, AC1Q6DR1, AC1Q6DR2, cid_8515, DSSTox_CID_20525, DSSTox_RID_79502, CBiol_002049, DSSTox_GSID_40525, Lopac0_000473, BMK1-G8, BSPBio_001066, ChemBiol10705 Compound 4, KBioGR_000406, KBioSS_000406, JMC517015 Compound 2, KSC516G2D, MLS002153267, MLS006011577, SCHEMBL170980, anthra[1,9-cd]pyrazol-6-one, GTPL5273, CHEMBL1725279, DTXSID2040525, SCHEMBL15583517, BCBcMAP01_000053, BDBM16018, CTK4B6321, KBio2_000406, KBio2_002974, KBio2_005542, KBio3_000771, KBio3_000772, MolPort-000-628-456, MolPort-002-914-349, MolPort-009-019-397, Bio1_000335, Bio1_000824, Bio1_001313, Bio2_000373, Bio2_000853, HMS1362F07, HMS1667K13, HMS1792F07, HMS1990F07, HMS2250C03, HMS3229I16, HMS3261O08, HMS3267P06, HMS3403F07, HMS3654P10, ALBB-024051, Anthra[1,9cd]pyrazol-6(2H)-one, BCP05457, c.i.70300, Tox21_110267, Tox21_500473, Anthra[1-9-cd]pyrazol-6(2H)-one, ANW-68872, BDBM50024294, BDBM50433916, CCG-47500, Dibenzo[cd,g]indazol-6(2H)-one #, HSCI1_000136, IN2388, s1460, SBB000595, ZINC96298875, AKOS000115584, Anthrapyrazolone; 1,9-Pyrazoloanthrone, CCG-100672, CS-0196, DB01782, LP00473, MCULE-7820194475, VA10299, 2,6-dihydrodibenzo[cd,g]indazol-6-one, IDI1_002128, QTL1_000077, SMP2_000240, NCGC00015958-01, NCGC00015958-02, NCGC00015958-04, NCGC00015958-05, NCGC00015958-06, NCGC00015958-07, NCGC00015958-08, NCGC00025186-01, NCGC00025186-02, NCGC00025186-03, NCGC00025186-04, NCGC00025186-05, NCGC00261158-01, WLN: T C6665 1A P IV OMNJ, AJ-50631, AN-43643, AS-14374, BAS 00719687, BC200202, CAS-129-56-6, CJ-11929, HY-12041, K914, KB-80675, LS-20607, SC-62298, SMR002530644, ST018684, TC-157617, TL8000704, EU-0100473, FT-0607068, ST24046474, EN300-02083, Anthra[1,9-cd]pyrazol-6(2H)-one & Z-100, K00068, S 5567, SP600125, >=98% (HPLC), AB00075935-01, SP 600125 & Z-100, 129S566, SR-01000075840-1, SR-01000075840-2, SR-01000075840-4, SR-01000075840-6, SR-01000637108-1, W-108360, BRD-K01567962-001-04-0, BRD-K01567962-001-06-5, BRD-K01567962-001-08-1, BRD-K01567962-001-22-2, Z56785477, F1414-1245, SP600125, 129-56-6, 14,15-diazatetracyclo[7.6.1.0(2),.0(1)(3),(1)]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one, 14,15-diazatetracyclo[7.6.1.0;{2,7}.0;{13,16}]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-8-one, 14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-8-one

ID: 99

InChIKey: ACSIXWWBWUQEHA-UHFFFAOYSA-N
SMILES: C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 25419
synonyms found at PubChem are:
Clodronic Acid, Clodronate, 10596-23-3, (Dichloromethylene)diphosphonic acid, Acido clodronico, Acide clodronique, Acidum clodronicum, Clodronsaeure, Dichloromethylidene diphosphonate, Dichloromethanediphosphonic acid, Bonefos, Methanedichlorodiphosphonic acid, Acide clodronique [INN-French], Acido clodronico [INN-Spanish], Acidum clodronicum [INN-Latin], Phosphonic acid, (dichloromethylene)bis-, (Dichloromethylene)bisphosphonic acid, dichloromethylenediphosphonic acid, [dichloro(phosphono)methyl]phosphonic acid, Clodronic acid [USAN:BAN:INN], UNII-0813BZ6866, Dichlormethylen-bis(phosphonsaeure), (Lip-C), EINECS 234-212-1, Methanedichlorodiphosphonate, BRN 1876367, (dichloromethanediyl)bis(phosphonic acid), Clodronic acid (USAN/INN), CHEMBL12318, (Dichloro-phosphono-methyl)-phosphonic acid, CLODRONATE DISODIUM, CHEBI:110423, Liposomes containing clodronic acid, Bonefos (TN), Dichloromethylenebisphosphonate, dichloromethylene-1,1-diphosphonic acid, dichloromethylene-1,1-bisphosphonic acid, 0813BZ6866, Acid, Clodronic, Sodium, Clodronate, Disodium, Clodronate, Dichloromethanediphosphonate, Clodronsaure, Diphosphonate, Dichloromethane, Dichloromethylene Biphosphonate, Biphosphonate, Dichloromethylene, Diphosphonate, Dichloromethylene, Acid, Dichloromethanediphosphonic, Clodronic acid [USAN:INN:BAN], Clodron (TN), Loron (TN), bisphosphonate clodronate, D00HNB, Lopac0_000398, SCHEMBL18982, GTPL9605, DTXSID8046959, KS-00000FXX, dichloromethylenebisphosphonic acid, ACSIXWWBWUQEHA-UHFFFAOYSA-N, dichloromethylene diphosphonic acid, HMS2089N14, dichloromethylene bisphosphonic acid, AC1L1936, BDBM50216172, HSCI1_000244, ZINC29747100, AKOS016013957, API0005165, DB00720, Phosphonic acid, (dichloromethylene)di-, (dichloro-phosphonomethyl)phosphonic acid, AK129751, CC-25916, KB-209170, LS-106549, FT-0603207, Phosphonic acid, (dichloromethylene)di-(8CI), D03545, Phosphonic acid, (dichloromethylene)di- (8CI), Z-3312, AB01275478-01, C-14853, BRD-K72542090-236-01-0

ID: 100

InChIKey: ACTIUHUUMQJHFO-UPTCCGCDSA-N
SMILES: CC1=C(C(=O)C(=C(C1=O)OC)OC)C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281915
synonyms found at PubChem are:
Coenzyme Q10, ubidecarenone, 303-98-0, ubiquinone-10, Ubiquinone 50, CoQ10, Neuquinon, Ubiquinone, Justquinon, Emitolon, Heartcin, Inokiten, Terekol, Udekinon, Luvacor, Ubiquinone 10, Coenzyme Q, Coenzyme Q 10, Coenzyme Q-10, CoQ 10, Neuquinone, Ubidecarenonum [Latin], Coenzyme Q(sub 10), Ubidecarenona [Spanish], CoQ(sub 10), Ubiquinone Q(sub 10), Vitamin Q, Q 199, coenzyme-Q10, Ube-Q, NSC 140865, UNII-EJ27X76M46, CCRIS 9016, Ubiquinone Q10, C59H90O4, EINECS 206-147-9, NSC 140665, CHEBI:46245, ACTIUHUUMQJHFO-UPTCCGCDSA-N, EJ27X76M46, API-31510, NCGC00159429-02, DSSTox_CID_26054, DSSTox_RID_81308, DSSTox_GSID_46054, 2-(3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, p-Benzoquinone, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, Ubidecarenona, Ubidecarenonum, 2,5-Cyclohexadiene-1,4-dione, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl, 2,5-Cyclohexadiene-1,4-dione, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, 2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all-E)-, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, 2-((all-E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-tetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CAS-303-98-0, Co-enzyme Q-10, ubisemiquinone radical, Q 10AA, Ubidecarenone [INN:JAN], Ubiquinone 10 (Coenzyme Q10), Co Q10, Armolipid, Mitocor, Akvion, NSC140865, CoenzymeQ10, Ubiquinone-Q10, Ubidecarenone [INN:BAN:JAN:NF], ubiquinone(10), NCGC00095322-03, KanekaQ10, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, 5-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethylt etraconta-2,6,10,14,18,22,26,30,34,38-decaenyl)-2,3-dimethoxy-6-methylcyclohex a-2,5-diene-1,4-dione, U10, all-trans-ubiquinone, Adelir (TN), Coenzymeq10,(S), BP31510, Co Enzyme Q-10, AC1NQZAC, PubChem13766, PubChem17408, UbidecarenoneCoenzymeQ10, AC1Q6BQD, Coenzyme Q10(CoQ10), D01ZUA, D0OT1A, Ubidecarenone (JP17/INN), SCHEMBL19858, MLS000028745, CHEMBL454801, Coenzyme Q10, 98% 1g, (non-labelled)Coenzyme Q10-d5, DTXSID6046054, SCHEMBL11901691, API-31510 (iv), Coenzyme Q10 (oral formulation), EX-A973, MolPort-016-633-346, Coenzyme Q10, analytical standard, (all-E)-2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione, HY-N0111, Tox21_111660, Tox21_113394, BPM-31510, LMPR02010001, s2398, SBB057402, ZINC85427689, Coenzyme Q10, >=98% (HPLC), AKOS015897104, AKOS015951232, AC-4352, AN-7252, DB09270, NSC-140865, Q-10; Ubiquinone 50; Ubiquinone-10, AS-13341, AT-16447, CPD000058651, H938, LS-40331, Q 10, SAM001246918, SMR000058651, AB1009286, TL8002341, C1971, Coenzyme Q10 (oral formulation), Receptagen, CS-0007796, N1796, ST50999657, CoQ10 platform technology, Ryan (Receptagen), A-2586, C-7060, C11378, D01065, J10064, 303C980, I08-0012, Ubidecarenone, European Pharmacopoeia (EP) Reference Standard, Ubidecarenone, United States Pharmacopeia (USP) Reference Standard, Ubidecarenone for system suitability, European Pharmacopoeia (EP) Reference Standard, Ubidecarenone for System Suitability, United States Pharmacopeia (USP) Reference Standard, 13448-14-1, 2,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, 2,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all-E)-, 2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all trans)-, 2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all-E)- (9CI), 2-((all-E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, (all trans)-, 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecenyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-DECAMETHYL-2,6,10,14,18,22,26,30,34,38-TETRACONTADECAEN-1-YL]-5,6-DIMETHOXY-3-METHYL-2,5-CYCLOHEXADIENE-1,4-DIONE, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone #, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone, 55127-92-9, 55870-43-4, p-Benzoquinone,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-

ID: 101

InChIKey: ACVGNKYJVGNLIL-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107896
synonyms found at PubChem are:
Gabazine, 105538-73-6, Gabazine free base, CHEBI:34968, SR95531, UNII-L45297DIU1, Tocris-1262, Prestwick0_000443, Prestwick1_000443, Prestwick2_000443, C13796, CHEMBL32503, L45297DIU1, 2-(3-Carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium, 6-imino-3-(4-methoxyphenyl)-1(6h)-pyridazinebutanoic acid, 1,6-Dihydro-6-imino-3-(4-methoxyphenyl)-1-pyridazinebutanoic acid, 4-(6-imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid, 4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1-yl)butanoic acid, 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid, 4-[6-imino-3-(4-methoxyphenyl)-1,6-dihydropyridazin-1-yl]butanoic acid, [3H]gabazine, J331.170H, Biomol-NT_000259, D0O5JC, SPBio_002425, AC1L32Y2, BPBio1_000771, GTPL4083, GTPL4197, SCHEMBL5529434, CTK8E8876, DTXSID20276043, ACVGNKYJVGNLIL-UHFFFAOYSA-N, 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, 4-(6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinyl)butanoic acid, ZINC2559949, BDBM50001572, PDSP1_001604, PDSP2_001588, ZINC02559949, AKOS030254307, NCGC00025088-01, NCGC00025088-02, NCGC00025088-03, RT-013069, FT-0668923, J-001443, BRD-K79905821-001-01-6, 4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl]-butyric acid, (gabazine)4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl]-butyric acid, 4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl]-butyric acid (gabazine or SR-95331), 4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl]-butyric acid(Gabazine)

ID: 102

InChIKey: ACVGWSKVRYFWRP-UHFFFAOYSA-N
SMILES: C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 65752
synonyms found at PubChem are:
Rutaecarpine, Rutecarpine, 84-26-4, Rutacarpine, Rutaecarpin, Rhetine, C18H13N3O, UNII-8XZV289PRY, NSC 258317, 8,13-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8XZV289PRY, CHEMBL85139, CHEBI:8922, Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-, Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro-, SMR001230721, SR-01000076104, Rutaecarpine,(S), Rutecarpine (8CI), Lopac-R-3277, Rutaecarpine (Rutecarpine), UPCMLD-DP040, Lopac0_001091, Oprea1_313284, cid_65752, MLS002153304, MLS006011796, SCHEMBL288507, AC1L23W8, Rutaecarpine, >98% (HPLC), UPCMLD-DP040:001, DTXSID00232884, ACVGWSKVRYFWRP-UHFFFAOYSA-N, MolPort-003-959-449, HMS2233M24, HMS3263K04, HMS3374B10, HMS3656C09, ZINC898237, ALBB-028246, BCP21309, HY-N0147, Tox21_501091, BBL028393, BDBM50131046, MFCD00210551, NSC258317, s2349, STL146385, AKOS005720935, CCG-205168, CS-6160, GS-3618, LP01091, MCULE-8799347749, NSC-258317, SMP2_000103, NCGC00015892-01, NCGC00015892-02, NCGC00015892-03, NCGC00015892-04, NCGC00015892-05, NCGC00015892-06, NCGC00015892-07, NCGC00015892-08, NCGC00094364-01, NCGC00094364-03, NCGC00094364-04, NCGC00261776-01, AN-42276, LS-83901, NCI60_002069, 1,1'-Hexamethylenebis (3,3-dimethylurea), AB0019845, EU-0101091, FT-0653229, N1344, R0102, V0371, C09238, J10443, R 3277, 210R551, I06-1291, Q-100850, SR-01000076104-2, SR-01000076104-6, 7,8-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one, Indolo[2',4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-, 8,13-Dihydro-7H-indolo[2'',3'':3,4]pyrido[2,1-b]quinazolin-5-one, 8,13-Dihydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one,8,13-dihydro-, 6,7-[Imino(1,2-phenylene)]-8,9-dihydro-11H-pyrido[2,1-b]quinazoline-11-one, Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro- (9CI), 3,13,21-triazapentacyclo[11.8.0.0(2),(1).0,.0(1),(2)]henicosa-1(21),2(10),4,6,8,15,17,19-octaen-14-one, 3,13,21-triazapentacyclo[11.8.0.0;{2,10}.0;{4,9}.0;{15,20}]henicosa-1(21),2(10),4,6,8,15,17,19-octaen-14-one, 3,13,21-triazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-1(21),2(10),4(9),5,7,15(20),16,18-octaen-14-one, 3,13,21-triazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-1(21),2(10),4,6,8,15,17,19-octaen-14-one, InChI=1/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H

ID: 103

InChIKey: ACWBQPMHZXGDFX-QFIPXVFZSA-N
SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 60846
synonyms found at PubChem are:
valsartan, 137862-53-4, Diovan, Provas, Tareg, L-Valsartan, CGP 48933, Exforge, Kalpress, Miten, Nisis, Vals, CGP-48933, (S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid, Valsarran, Valsartan [USAN:INN], [3H]valsartan, UNII-80M03YXJ7I, Diovan (TN), N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine, CHEMBL1069, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine, 80M03YXJ7I, CHEBI:9927, 137863-60-6, C24H29N5O3, (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid, (s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid, N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine, (S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine, N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine, L-Valine, N-(1-oxopentyl)-N-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, walsartan, N-[p-(o-1H-Tetrazol-5-ylphenyl)benzyl]-N-valeryl-L-valine, Valzaar, Valtan, N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine, N-(1-OXOPENTYL)-N-[[2'-(2H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-L-VALINE, N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine, SMR000466318, CEPA brand of valsartan, Lacer brand of valsartan, Sanol brand of valsartan, Esteve brand of valsartan, Aventis brand of valsartan, Schwarz brand of valsartan, Novartis brand of valsartan, cardopan, valsartanin, Prexxartan, Valpression, Varexan, HSDB 7519, (S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid, Diovan, Valsartan, L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, N-PENTANOYL-N-([2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL]METHYL)-L-VALINE, Valsartan [USAN:USP:INN:BAN], Valsartan,(S), (2S)-3-Methyl-2-(pentanoyl-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)amino)butanoic acid, (2S)-3-methyl-2-[pentanoyl-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid, (S)-3-METHYL-2-(PENTANOYL-[2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-AMINO)-BUTYRIC ACID, (S)-3-METHYL-2-[N-((4-[2-(2H-1,2,3,4-TETRAZOL-5-YL)PHENYL]PHENYL)METHYL)PENTANAMIDO]BUTANOIC ACID, (S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid, valsartan (Diovan), Valzaar (TN), Valtan (TN), ANGIOTAN, PubChem9865, Spectrum_001796, AC1Q5QIK, Spectrum2_001120, Spectrum3_001831, Spectrum4_000749, Spectrum5_001582, D04HSR, D06UDG, Prexxartan (oral solution), EC 604-045-2, AC1L1U1M, SCHEMBL2542, BSPBio_003501, GTPL593, KBioGR_001078, KBioSS_002289, MLS000759423, MLS001424088, Valsartan (JAN/USAN/INN), BIDD:GT0345, SPECTRUM1505209, SPBio_001260, GTPL3937, Valsartan (JP17/USAN/INN), Valsartan, >=98% (HPLC), KBio2_002287, KBio2_004855, KBio2_007423, KBio3_003006, KS-00000ISS, EZR-104, VAL-489, ACWBQPMHZXGDFX-QFIPXVFZSA-N, MolPort-002-507-854, MolPort-003-666-608, HMS1922L21, HMS2051L12, HMS2093K22, HMS2232F05, HMS3651E04, HMS3715P12, Pharmakon1600-01505209, ACT02671, BCP05184, ZINC3875259, ANW-49040, BDBM50049186, BG0645, GP8514, MFCD00865840, NSC758927, s1894, AKOS015914315, AKOS015994698, AB07510, AC-4543, AM90287, AN-7255, CCG-101028, CCG-221275, CS-1967, DB00177, DS-1248, KS-1194, MCULE-6728882368, NC00278, NSC-758927, RTR-031794, VA11929, AK-58790, BC204156, BR-58790, CPD000466318, HY-18204, I997, SAM001246581, SC-00971, SBI-0206738.P001, AB0013966, AB2000354, AX8018200, LS-161334, ST2408288, TL8000869, TR-031794, FT-0631156, 4997-EP2270011A1, 4997-EP2272841A1, 4997-EP2277879A1, 4997-EP2295406A1, 4997-EP2295422A2, 4997-EP2298772A1, 4997-EP2298776A1, 4997-EP2298779A1, 4997-EP2301923A1, 4997-EP2301931A1, 4997-EP2301936A1, 4997-EP2305219A1, 4997-EP2308562A2, 4997-EP2308839A1, 62V534, D00400, J10013, S-6418, AB00639940-06, AB00639940-08, AB00639940_09, AB00639940_11, SR-05000001928, J-007068, SR-05000001928-1, BRD-K45158365-001-02-3, BRD-K45158365-001-05-6, I14-41498, Valsartan, European Pharmacopoeia (EP) Reference Standard, N-Valeryl-N-[2'-(5-tetrazolyl)biphenyl-4-ylmethyl]-L-valine, Valsartan, United States Pharmacopeia (USP) Reference Standard, Valsartan, Pharmaceutical Secondary Standard; Certified Reference Material, (5)-2-{N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]pentanamido}-3-methylbutanoic acid, (S)-N-BUTYRYL-N-([2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL]METHYL)-VALINE, 3-Methyl-2-{pentanoyl-[2''-(1H-tetrazol-5-yl)-biphenyl-4-yl]-amino}-butyric acid, L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-(9CI), L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, N-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-pentanoyl-L-valine, N-(1-oxopentyl)-N-[[2'-(1h-tetrazol-5-yl) [1,1'-bi-phenyl]-4-yl]methyl]-l-valine, N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-(L)-valine, N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-L-valine, Valsartan for peak identification, European Pharmacopoeia (EP) Reference Standard, Valsartan for system suitability, European Pharmacopoeia (EP) Reference Standard, (2S)-3-METHYL-2-(PENTANOYL-[2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-AMINO)-BUTYRIC ACID, (2S)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid, (2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid, (2S)-3-Methyl-2-{N-pentanoyl-N'-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butanoic acid, (s)-3-methyl-2-(pentanoyl-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino)-butyric acid 137862-53-, (s)-3-methyl-2-[N-({4-[2-(2h-1,2,3,4-tetrazol-5-yl) phenyl]phenyl}methyl)pentanamido]butanoic acid, (s)-3-methyl-2-{pentanoyl-[-2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid, (S)-3-Methyl-2-{pentanoyl-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid, (S)-3-Methyl-2-{pentanoyl-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid, (S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)biphenyl-4-yl-methyl]amine, (S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amine, (S)-N-(1-Carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-amine, 2-{[2''-(2,3-Dihydro-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-pentanoyl-amino}-3-methyl-butyric acid, 3-Methyl-2-{((S)-pentanoyl)-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid

ID: 104

InChIKey: ADFCQWZHKCXPAJ-GFCCVEGCSA-N
SMILES: C1[C@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: potent ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 91469
synonyms found at PubChem are:
Equol, 531-95-3, (S)-3-(4-Hydroxyphenyl)chroman-7-ol, (S)-Equol, S-Equol, (-)-(S)-Equol, (-)-Equol, UNII-2T6D2HPX7Q, 4',7-Isoflavandiol, CCRIS 9222, EINECS 208-522-2, (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 2T6D2HPX7Q, CHEMBL198877, CHEBI:34741, (S)-(-)-4',7-Isoflavandiol, (3S)-3-(4-hydroxyphenyl)chroman-7-ol, 4',7-Dihydroxyisoflavan, 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-, 3,4-Dihydro-3-(4-hydroxyphenyl)-(S)-2H-1-benzopyran-7-ol, (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol, 7,4'-dihydroxyisoflavan, 7,4'-Isoflavandiol, (3S)-Equol, Equol, (-)-, SE 5OH, AC1L3M4Y, SCHEMBL43647, BIDD:ER0148, DTXSID0022309, AOB5550, AUS 131, AUS-131, ADFCQWZHKCXPAJ-GFCCVEGCSA-N, MolPort-003-847-078, ZINC388661, (3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, ACT03253, BCP13598, EX-A1354, 2127AH, BDBM50410528, s2450, 4',7-dihydroxy-3,4-dihydroisoflavone, ACN-001462, CS-7937, DB11674, MCULE-5874318771, 7-hydroxy-3-(4'-hydroxyphenyl)chroman, (3s)-3-(4-hydroxyphenyl)-7-chromanol, NCGC00386208-01, AJ-20722, AK-72897, AN-45630, BR-72897, CJ-03317, LS-39394, SC-19277, ZB011640, AX8015938, HY-100583, KB-211349, FT-0649148, ST24026586, C14131, S-2179, 531D953, (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, UNII-2RZ8A7D0E8 component ADFCQWZHKCXPAJ-GFCCVEGCSA-N, 3,4-dihydro-3-(4- hydroxyphenyl)-(S)-2H-1-benzopyran-7-ol, 20879-01-0

ID: 105

InChIKey: ADFCQWZHKCXPAJ-LBPRGKRZSA-N
SMILES: C1[C@@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: potent ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 6950272
synonyms found at PubChem are:
(R)-Equol, R-Equol, Equol, 221054-79-1, UNII-2V8RAP1HXA, 2V8RAP1HXA, Equol, (+)-, (R)-3-(4-hydroxyphenyl)chroman-7-ol, (3R)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, Isoequol, (+)-Equol, AC1OCT9N, SCHEMBL2002128, CHEMBL3127843, MolPort-002-507-289, ZINC388660, EX-A1353, KS-000010MK, 1091AH, BBL026747, STK801893, AKOS004120071, CS-8182, MCULE-6555642673, AJ-20721, CJ-03316, ZB011639, HY-108414, FT-0772959, UNII-2RZ8A7D0E8 component ADFCQWZHKCXPAJ-LBPRGKRZSA-N, 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3R)-

ID: 106

InChIKey: ADFCQWZHKCXPAJ-UHFFFAOYSA-N
SMILES: C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O

biological descriptors:

CFTR relevance: potent ΔF508 CFTR activation

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"JP Clancy" "SM Rowe" "S Barnes" "J Prasain" "LC Pyle" "PA Sloane" "K Backer" "JC Fulton" "M Mazur"

CID is 382975
synonyms found at PubChem are:
94105-90-5, 3-(4-hydroxyphenyl)chroman-7-ol, Equol, (+/-)-Equol, (R,S)-Equol, 7,4'-Homoisoflavane, 4',7-Dihydroxyisoflavane, (RS)-Equol, 3-(4-hydroxyphenyl)-7-chromanol, ( inverted exclamation markA)-Equol, 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, 4',7-Isoflavandiol, ADFCQWZHKCXPAJ-UHFFFAOYSA-N, 3-(4-Hydroxy-phenyl)-chroman-7-ol, 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol, 66036-38-2, 4',7-Dihydroxyisoflavan, 3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, 7,4'-dihydroxyisoflavan, Equol, (+/-)-, Rac-Equol, R,S-Equol, (+/-)Equol, AC1L8KFS, 4',7-Dihydroxyflavandiol, AC1Q7A6Q, (.+/-.)-Equol, SCHEMBL43648, SCHEMBL949461, BIE531, CHEMBL1957037, DTXSID7058705, 531-95-3 (S-isomer), CTK5H4974, NV 07|A, EQUOL,(+/-)-(SH), MolPort-003-847-077, ZX-AFC000526, HMS3648G10, HMS3651B05, EX-A1352, KS-00000Q4S, ZX-AT019275, (+/-) 7,4'-Dihydroxy Isoflavane, ANW-43844, GP9597, LMPK12080003, MFCD00016662, NSC670882, 7-Hydroxy-3-(4-hydroxyphenyl)chroman, AKOS015899541, CS-6870, DS-2344, HY-100583A, MCULE-1358694468, NSC-670882, OR60026, VA10827, SMP2_000187, AK-99885, KB-50551, SC-94870, (S)-3-(4-Hydroxy-phenyl)-chroman-7-ol, AX8232306, RT-012437, (+/-)-Equol, >=99.0% (TLC), 4 inverted exclamation mark ,7-Isoflavandiol, 4CH-011868, E0922, FT-0081331, FT-0660903, ST24022579, ST50331725, W6768, Z5370, M-9676, SR-01000946366, I06-0305, J-014504, SR-01000946366-1, BRD-A74907996-001-01-8, I14-11532, (+/-)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-chromen-7-ol, 2H-1-Benzopyran-7-ol,3,4-dihydro-3-(4-hydroxyphenyl)-

ID: 107

InChIKey: ADTCHPRGRVJTBH-UHFFFAOYSA-M
SMILES: C1N2C=C(C3=CC=CC=C3C2=NC4=[N+]1C=C(C5=CC=CC=C54)Br)Br.[I-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 404655
synonyms found at PubChem are:
NSC721081, AC1L8NQ8, CHEMBL1996574, CTK5I8846, NSC-721081, 5,11-dibromo-8h-[1,3,5]triazino[2,1-a:4,5-a']diisoquinolin-7-ium iodide

ID: 108

InChIKey: ADVPTQAUNPRNPO-REOHCLBHSA-N
SMILES: C([C@@H](C(=O)O)N)S(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1549098
synonyms found at PubChem are:
L-Cysteinesulfinic acid, 1115-65-7, 3-Sulfino-L-alanine, 3-sulfinoalanine, Cysteinesulfinic acid, 3-sulphino-L-alanine, (2R)-2-amino-3-sulfinopropanoic acid, L-Cysteinesulphinic Acid, L-Alanine, 3-sulfino-, Cysteine sulfinic acid, L-Cysteine sulfinic acid, Cysteine sulfinate, L-cysteine sulphinic acid, CHEBI:16345, ADVPTQAUNPRNPO-REOHCLBHSA-N, 3-sulfinato-L-alaninate, UNII-56X032NVQL, 56X032NVQL, S-sulfinocysteine, S-cysteinesulfinic acid, Tocris-0216, L-CSA, AC1LU7QV, Biomol-NT_000190, bmse000706, D0S4NR, Lopac0_000263, SCHEMBL189097, BPBio1_001212, GTPL5447, CHEMBL1160508, CTK0H5128, MolPort-006-112-940, HMS3260F08, Tox21_500263, ZINC19419008, AKOS006280503, CCG-204358, DB02153, LP00263, NCGC00024500-01, NCGC00024500-02, NCGC00024500-03, NCGC00024500-04, NCGC00024500-05, NCGC00260948-01, B6225, EU-0100263, FT-0633338, C 4418, C00606, SR-01000075758, SR-01000597398, SR-01000075758-1, SR-01000597398-1, FF909059-FA51-40A0-8973-9E4ECFB8C92A, UNII-UZY4HYK4ZX component ADVPTQAUNPRNPO-REOHCLBHSA-N

ID: 109

InChIKey: AEMFNILZOJDQLW-QAGGRKNESA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6128
synonyms found at PubChem are:
androstenedione, 4-Androstene-3,17-dione, Androst-4-ene-3,17-dione, 63-05-8, 4-Androstenedione, Androtex, 3,17-Dioxoandrost-4-ene, delta-4-Androstenedione, SKF 2170, Fecundin, delta-4-Androsten-3,17-dione, delta-4-Androstene-3,17-dione, 4-ANDROSTENE-3-17-DIONE, 4-Androsten-3,17-dione, NSC 9563, delta-(sup4)-Androsten-3,17-dione, delta(sup 4)-Androstene-3,17-dione, 17-Ketotestosterone, UNII-409J2J96VR, d4-androstenedione, CHEBI:16422, Androstenedione [JAN], HSDB 7335, EINECS 200-554-5, MLS000028510, Delta(4)-androsten-3,17-dione, NSC9563, AEMFNILZOJDQLW-QAGGRKNESA-N, 409J2J96VR, Delta(4)-androstene-3,17-dione, .DELTA.4-Androstene-3,17-dione, (8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione, Androstenedione (JAN), NCGC00023902-06, SMR000058281, DSSTox_CID_4523, DSSTox_RID_77443, DSSTox_GSID_24523, CAS-63-05-8, (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione, 117598-81-9, ASD, CHEMBL274826, adione, delta4-androstenedione, Androsten-3,17-dione, AC1L1LUU, Opera_ID_1694, Spectrum5_002059, [4-14C]-androstenedione, D03TIX, D0M8RO, D0O3GO, Epitope ID:135869, EC 200-554-5, AC1Q6O8G, androst-4-en-3,17-dione, BIDD:PXR0101, D4-Androstene-3,17-dione, Lopac0_000114, SCHEMBL23272, KSC353K6T, MLS000563086, MLS002152886, (4)-Androsten-3,17-dione, GTPL2860, DTXSID8024523, BDBM91713, CTK2F3569, DELTA4-Androstene-3,17-dione, .delta.4-Androsten-3,17-dione, Androst-4-en-3,17-dione, 2, HMS2231F18, NSC-9563, ZINC4428526, Tox21_110893, Tox21_202269, Tox21_300579, BBL033517, c1015, LMST02020007, MFCD00003615, STK801871, AKOS005622710, Tox21_110893_1, [4-14C]androst-4-ene-3,17-dione, CCG-204209, DB01536, LS-2167, MCULE-8902385122, RTR-021722, SHG0000068, .delta.-(sup4)-Androsten-3,17-dione, Estr-5-ene-3,17-diol,(3b,17b)-, NCGC00023902-03, NCGC00023902-04, NCGC00023902-05, NCGC00023902-07, NCGC00023902-08, NCGC00023902-09, NCGC00254238-01, NCGC00259818-01, AC-11042, Androstenedione; 3,17-Dioxo-4-andostene, SC-46873, AB0090630, DB-054395, KB-145875, A0845, androst-4-ene-3,17-dione (androstenedione), EU-0100114, FT-0082072, FT-0657562, Androstenedione (Androst-4-ene-3,17-dione), WLN: L E5 B666 FV OV MUTJ A1 E1, A 9630, C00280, D00051, SR-01000003096, SR-01000075697, SR-01000003096-4, SR-01000075697-1, W-104936, I14-14300, 8F5F4DCB-1164-4F2C-B4E3-3B74F684B189, 4-Androstene-3,17-dione, VETRANAL(TM), analytical standard, Androstenedione (Androst-4-ene-3,17-dione) 1.0 mg/ml in Acetonitrile, 104534-78-3

ID: 110

InChIKey: AEOCXXJPGCBFJA-UHFFFAOYSA-N
SMILES: CCC1=NC=CC(=C1)C(=S)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3287
synonyms found at PubChem are:
ethionamide, 536-33-4, Ethioniamide, 2-ethylpyridine-4-carbothioamide, Ethyonomide, Amidazine, Etionamid, Etioniamid, Ethylisothiamide, Ethinamide, Thioamide, Trecator, Trecator-SC, Amidazin, Ethimide, Etiocidan, Etionizin, Etionizina, Etionizine, Fatoliamid, Iridocin, Iridozin, Isotiamida, Itiocide, Nicotion, Rigenicid, Sertinon, Thianide, Thioniden, Trekator, Trescatyl, Trescazide, Tubenamide, Tubermin, Tuberoid, Tuberoson, Aetina, Aetiva, Ethina, Etimid, Etionid, Isothin, Nizotin, Teberus, Thianid, Tianid, Atina, 2-Ethylthioisonicotinamide, Ethionamid prothionamid, 4-Pyridinecarbothioamide, 2-ethyl-, Iridocin Bayer, Aethionamidum, Ethionamidum, Etionamida, Etionamide, Nisotin, Thiomid, Bayer 5312, Etionamide [DCIT], Tio-Mid, 2-ETHYL-4-PYRIDINECARBOTHIOAMIDE, Tiomid, 2-Ethylisothionicotinamide, 2-Ethylisonicotinothioamide, Ethionamidum [INN-Latin], Etionamida [INN-Spanish], Trecator SC, Ethina (VAN), 2-Ethyl-4-thiocarbamoylpyridine, 2-Ethyl-thioisonicotinamide, 1314 TH, 2-Ethylisonicotinic acid thioamide, TH 1314, NCI-C01694, alpha-Ethylisothionicotinamide, alpha-Ethylthioisonicotinamide, Ethatyl, alpha-Ethylisonicotinoylthioamide, UNII-OAY8ORS3CQ, 2-ethyl-4-thiopyridylamide, F.I. 58-30, 1314TH, alpha-Ethylisonicotinic acid thioamide, 2-Ethylisonicotinic thioamide, 2-Ethyl-4-thioamidylpyridine, CCRIS 287, Isonicotinamide, 2-ethylthio-, C8H10N2S, Trecator-SC (TN), HSDB 7473, Bayer5312, 1314-Th, OAY8ORS3CQ, Ethionamide [USAN:INN:BAN:JAN], 3-Ethylisothionicotinamide, EINECS 208-628-9, 2-e thylisothionicotinamide, NSC 255115, BRN 0116474, 2-Ethylisonicotinoylthioamide, alpha-ethylt hioisonicotinamide, MLS000069764, CHEBI:4885, .alpha.-Ethylisothionicotinamide, .alpha.-Ethylthioisonicotinamide, 2-ethylisonicotinic acid thiomide, AEOCXXJPGCBFJA-UHFFFAOYSA-N, .alpha.-Ethylisonicotinoylthioamide, 2-ethyl-4-aminothiocarbonylpyridine, Isonicotinimidic acid, 2-ethylthio-, NSC255115, 1314 TN, .alpha.-Ethylisonicotinic acid thioamide, NCGC00016497-05, CAS-536-33-4, CPD001370750, SMR000058716, DSSTox_CID_577, E0695, DSSTox_RID_75669, DSSTox_GSID_20577, W-105719, amino(2-ethyl(4-pyridyl))methane-1-thione, SR-01000759219, Thiodine, Prestwick_842, Ethionamide [USAN:USP:INN:BAN:JAN], PubChem15920, Spectrum_001082, Opera_ID_632, AC1MC4CB, Prestwick0_000526, Prestwick1_000526, Prestwick2_000526, Prestwick3_000526, Spectrum2_000994, Spectrum3_000428, Spectrum4_000547, Spectrum5_000979, 2-Ethylisonicotinothiamide, 2-Ethylisonicotinthioamide, D0P0HB, Wyeth Brand of Ethionamide, CHEMBL1441, SCHEMBL27007, BSPBio_000511, BSPBio_002016, KBioGR_001213, KBioSS_001562, 5-22-02-00360 (Beilstein Handbook Reference), KSC492I0R, MLS001074114, MLS002454402, DivK1c_000145, SPECTRUM1500292, WLN: T6NJ B2 DYZUS, SPBio_001087, SPBio_002432, BPBio1_000563, Ethionamide (JP15/USP/INN), Ethionamide (JP17/USP/INN), DTXSID0020577, AEOCXXJPGCBFJA-UHFFFAOYSA-, CTK3J2408, HMS500H07, KBio1_000145, KBio2_001562, KBio2_004130, KBio2_006698, KBio3_001236, KS-00000FAO, .alpha.-Ethyl-thioisonicotinamide, Isonicotinamide, 2-ethyl, thio-, MolPort-000-159-777, NINDS_000145, HMS1569J13, HMS1920M22, HMS2091F03, HMS2096J13, HMS2231F10, HMS2233J11, HMS3259K17, HMS3370I18, HMS3371D12, HMS3655M10, HMS3713J13, Pharmakon1600-01500292, HY-B0276, ZINC3872520, Tox21_110458, Tox21_202409, Tox21_302769, ANW-42028, CCG-40212, FCH919543, GA6196, LS-199, NSC757028, s1777, SBB055548, AKOS006220662, Tox21_110458_1, CS-2266, DB00609, FS-1770, MCULE-1322319906, NC00508, NSC-255115, NSC-757028, RTC-061432, IDI1_000145, NCGC00016497-01, NCGC00016497-02, NCGC00016497-03, NCGC00016497-04, NCGC00016497-06, NCGC00016497-08, NCGC00016497-09, NCGC00091074-01, NCGC00091074-02, NCGC00091074-03, NCGC00091074-04, NCGC00256600-01, NCGC00259958-01, AC-13715, AK163496, AN-45683, CC-27545, CJ-10999, KB-50586, M381, SAM002554899, SMR001370750, SBI-0051377.P003, AB0015183, AB2000288, AX8010649, TC-061432, AB00051990, ST24046699, ST50949989, C07665, D00591, 2-ethylthioisonicotinamide;Trecator SC;Amidazine, 33010-EP2286812A1, 33010-EP2287165A2, 33010-EP2287166A2, 33010-EP2292620A2, 33010-EP2297130A1, 33010-EP2301536A1, 33010-EP2301538A1, 33010-EP2305675A1, 33010-EP2305695A2, 33010-EP2305696A2, 33010-EP2305697A2, 33010-EP2305698A2, 33010-EP2305808A1, 33010-EP2308833A2, 33010-EP2308852A1, 33010-EP2308874A1, 33010-EP2311455A1, 33010-EP2311815A1, 73833-EP2308926A1, 73833-EP2309564A1, AB00051990-09, AB00051990_10, AB00051990_11, A829694, C-04805, SR-01000759219-2, SR-01000759219-5, BRD-K33710385-001-05-4, BRD-K51207550-001-09-9, Ethionamide, European Pharmacopoeia (EP) Reference Standard, 2-ethylthioisonicotinamide, Trecator SC, Amidazine, Ethionamide, Ethionamide, United States Pharmacopeia (USP) Reference Standard, Ethionamide for system suitability, European Pharmacopoeia (EP) Reference Standard, InChI=1/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)

ID: 111

InChIKey: AEQFSUDEHCCHBT-UHFFFAOYSA-M
SMILES: CCCC(CCC)C(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 14047
synonyms found at PubChem are:
Sodium valproate, Sodium 2-propylpentanoate, 1069-66-5, Valproate sodium, Valproic acid sodium salt, Eurekene, Labazene, Orfiril, Epilim, Valproic acid sodium, Valerin, Natrium valproat, Sodium 2-propylvalerate, 2-Propylvaleric acid sodium salt, 2-Propylpentanoic acid sodium salt, DEPACON, Dipropylacetate sodium, Sodium dipropylacetate, Sodium bispropylacetate, Valproinsaeure, natrium, Sodium n-dipropylacetate, Pentanoic acid, 2-propyl-, sodium salt, UNII-5VOM6GYJ0D, Valproic Acid, Sodium Salt, Valproic Acid (sodium salt), 2-propylpentanoic acid sodium, Sodium 2-n-propyl-pentanoate, Valproate, Valproic acid sodium salt (1:1), 2-Propyl pentanoic acid, KW 6066N, EINECS 213-961-8, 5VOM6GYJ0D, Valproate Sodium [USAN], Valeric acid, 2-propyl-, sodium salt, 2-Propylpentanoic Acid, Na, CHEBI:9925, sodium;2-propylpentanoate, Valproate sodium (USAN), Q-201918, Sodium valproate (2-Propylpentanoic acid, sodium salt), Valproic acid sodium salt (Sodium valproate), CHEMBL433, SMR000875243, Valproate sodium [USAN:USP], A-44090, Selenica (TN), dipropylacetatesodium, potassium dipropylacetate, Sodium2-propylpentanoate, Lopac-P-4543, kw6066n, Sodium valproate (JP17), D0R5HK, AC1Q1V4P, Valproate Sodium (Depacon), 2-propylvalericacidsodiumsalt, DSSTox_CID_17072, DSSTox_RID_79301, 2-propyl-valericacisodiumsalt, DSSTox_GSID_37072, SCHEMBL35027, MLS001332431, MLS001332432, MLS002153189, SPECTRUM1500606, 2-propyl-pentanoicacisodiumsalt, ABBOTT-44090, DTXSID5037072, CTK6D3458, HMS500N15, KS-00000WRE, Valproic acid sodium salt, 98%, AEQFSUDEHCCHBT-UHFFFAOYSA-M, MolPort-003-666-306, HMS1921I21, HMS2092C12, HMS2230E16, HMS3262B20, HMS3369L11, HMS3648A12, HMS3654I14, BCP02888, Tox21_302623, Tox21_500889, ANW-15465, BG0351, CCG-40071, HY-10585A, MFCD00078604, s1168, AKOS005066057, AC-8391, AN-8062, CCG-208088, CS-1764, LP00889, NCGC00016192-01, NCGC00016192-02, NCGC00016192-03, NCGC00016192-04, NCGC00094208-01, NCGC00094208-02, NCGC00094208-03, NCGC00167849-01, NCGC00256651-01, NCGC00261574-01, AS-13150, H456, BCP0726000316, CAS-1069-66-5, AB0013058, KB-259787, LS-161174, ST2419859, EU-0100889, FT-0633278, S0894, D00710, M-2892, P 4543, C-36561, I01-1195, Sodium valproate, European Pharmacopoeia (EP) Reference Standard

ID: 112

InChIKey: AERBNCYCJBRYDG-KSZLIROESA-N
SMILES: CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)N)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 122121
synonyms found at PubChem are:
phytosphingosine, 554-62-1, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, 4-D-Hydroxysphinganine, D-Ribo-phytosphingosine, UNII-GIN46U9Q2Q, 4R-hydroxysphinganine, C18-Phytosphingosine, 4-hydroxysphinganine, GIN46U9Q2Q, CHEBI:46961, AERBNCYCJBRYDG-KSZLIROESA-N, 1,3,4-Octadecanetriol, 2-amino-, (2S,3S,4R)-, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol, 388566-94-7, Phytosphingosin, C18H39NO3, 4D-Hydroxysphinganine, 4-D-hydroxy-Sphinganine, EC 439-210-6, AC1L3U0M, AC1Q2W1B, SCHEMBL20110, C18-PHS, (+)-D-ribo-Phytosphingosine, 4-R-hydroxyoctadecasphinganine, CHEMBL236036, CTK4B9855, DTXSID80203951, MolPort-003-959-216, BCP23610, ZINC8437018, 5544AE, ANW-32318, LMSP01030001, AKOS015949172, AKOS016015084, AN-7028, CCG-208251, RP08034, D-ribo-2-amino-1,3,4-Octadecanetriol, SMP2_000142, NCGC00163609-01, AK128971, AX8147979, KB-206703, TR-037073, FT-0673891, P1765, ST24034134, 4-hydroxysphinganine (Saccharomyces Cerevisiae), C12144, SR-05000002328, J-501034, SR-05000002328-2, (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol, AldrichCPR, [2S-(2R*,3R*,4S*)]-2-amino-1,3,4-Octadecanetriol, 1,3,4-Octadecanetriol, 2-amino-, (2S-(2R*,3R*,4S*))-, PHYTOSPHINGOSINE PHYTOSPHINGOSINE HYDROCHLORIDE (2S, 3S, 4R)-2-AMINO-1,3,4-OCTADECANETRIOL 4-HYDROXYSPHINGANINE 4-HYDROXYSPHINGANIN

ID: 113

InChIKey: AEVKYFNHIADTEI-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O.O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 18542136
synonyms found at PubChem are:
morin dihydrate, Morin hydrate, 6472-38-4, ST059837, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one, hydrate, hydrate, morin fluka, DSSTox_CID_20776, DSSTox_RID_79597, DSSTox_GSID_40776, SCHEMBL7116848, CHEMBL3184401, DTXSID3040776, C15H10O7.2H2O, Tox21_301216, 6261AF, SBB009921, AKOS024283060, Using SMILES with the ChemDraw Plugin, NCGC00255404-01, CAS-654055-01-3, Morin 2-hydrate (C.I. 75660), Reag., 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one dihydrate

ID: 114

InChIKey: AFHXRFIYCWKUKA-UHFFFAOYSA-N
SMILES: CC(=O)C1=C(C=C(C=C1)OCC2=CC=C(C=C2)OC)O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 11323232
synonyms found at PubChem are:
SCHEMBL3540404, AFHXRFIYCWKUKA-UHFFFAOYSA-N, ZINC34472731, 2'-Hydroxy-4'-(4-methoxybenzyloxy)acetophenone, 1-(4-(4-methoxybenzyloxy)-2-hydroxyphenyl)ethanone, 1-[2-hydroxy-4-(4-methoxy-benzyloxy)-phenyl]-ethanone, 1-[2-Hydroxy-4-(4-methoxy-benzyloxy)-phenyl]ethanone, 1-(2-HYDROXY-4-((4-METHOXYPHENYL)METHOXY)PHENYL)ETHANONE

ID: 115

InChIKey: AFIIOPIEVQSYHH-UHFFFAOYSA-M
SMILES: C[N+](C)(C)CCOC(=O)CBr.[Br-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957478
synonyms found at PubChem are:
Bromoacetylcholine bromide, 22004-27-9, 17139-54-7, BROMOACETYLCHOLINE BROMIDE INHIBITOR OF CHOLINE, 2-(2-Bromoacetyloxy)-N.,N,N-trimethylethanaminium bromide, EU-0100196, MLS002153520, SCHEMBL1320993, CHEMBL1255831, CTK4D3929, HMS2233F19, HMS3260H13, REGID_for_CID_11957478, Tox21_500196, MFCD00078570, CCG-221500, LP00196, ACM17139547, NCGC00093672-01, NCGC00260881-01, SMR000326753, B-121, SR-01000075729, J-014415, SR-01000075729-1, Ethanaminium,2-[(2-bromoacetyl)oxy]-N,N,N-trimethyl-, 2-(2-Bromoacetyloxy)-N,N,N-trimethylethanaminium bromide

ID: 116

InChIKey: AFLDFEASYWNJGX-UHFFFAOYSA-N
SMILES: CC(C)NC(C)CC1=CC=C(C=C1)I.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 55305
synonyms found at PubChem are:
Iofetamine hydrochloride, 4-Iodo-N-isopropylamphetamine hydrochloride, 116316-03-1, 82691-32-5, IOFETAMINE HYDROCHLORIDE I-123, NCGC00094048-01, Iofetamine I123 hydrochloride, 95896-48-3, Spectamine, 1-(4-iodophenyl)-N-propan-2-ylpropan-2-amine, Iofetamine HCl, ((sup 123)I)(+-)-N-Isopropyl-p-iodoamphetamine hydrochloride, (+-)-p-Iodo-(sup 123)I-N-isopropyl-alpha-methylphenethylamine hydrochloride, Benzeneethanamine, 4-(iodo-(sup 123)I)-alpha-methyl-N-(1-methylethyl)-, hydrochloride, (+-)-, AC1L1ITG, D0YQ5L, ACMC-1BU12, DSSTox_CID_25774, DSSTox_RID_81116, DSSTox_GSID_45774, (+/-)-N-Isopropyl-p-Iodoamphetamine hydrochloride, MLS002153161, SCHEMBL7755724, CHEMBL1255865, DTXSID3045774, CTK0H3361, Tox21_111239, Tox21_500694, AKOS015908631, Benzeneethanamine, 4-iodo-alpha-methyl-N-(1-methylethyl)-, hydrochloride, CCG-221998, LP00694, VZ29246, Benzeneethanamine, 4-iodo-alpha-methyl-N-(1-methylethyl)-, hydrochloride (1:1), Benzeneethanamine, 4-iodo-alpha-methyl-N-(1-methylethyl)-, hydrochloride, (+/-)-, NCGC00261379-01, SMR001230655, N-Isopropyl-p-iodoamphetamine hydrochloride, CAS-82691-32-5, DB-041308, LS-186659, EU-0100694, FT-0642831, I-120, A803593, SR-01000075216, SR-01000075216-1, I14-34654, 1-(4-Iodophenyl)-N-isopropylpropan-2-amine hydrochloride, 1-(4-iodophenyl)-N-propan-2-yl-2-propanamine hydrochloride, 1-(4-iodophenyl)-N-propan-2-ylpropan-2-amine hydrochloride, 1-(4-iodophenyl)-N-propan-2-yl-propan-2-amine hydrochloride, Iofetamine hydrochloride, analytical standard, for drug analysis, ( inverted exclamation markA)-2-(N-Isopropyl)amino-4 inverted exclamation marka-iodophenylpropane, AC1MC62O, 1-(4-iodophenyl)propan-2-yl-propan-2-ylazanium chloride

ID: 117

InChIKey: AFMHCDNELHMGHI-DUXPYHPUSA-N
SMILES: CC1=C(C(=O)C=CO1)/C=C/O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5986986
synonyms found at PubChem are:
2-METHYL-3-HYDROXYETHYLENEPYRAN-4-ONE, Spectrum5_000444, BSPBio_003466, AC1O0D89, CHEMBL3039152, CCG-38765, NCGC00178047-01, 3-[(E)-2-hydroxyethenyl]-2-methylpyran-4-one

ID: 118

InChIKey: AFPLNGZPBSKHHQ-MEGGAXOGSA-N
SMILES: CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CC/C(=C/CO)/C)/C)/C)/C)/C)/C)/C)/C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5477212
synonyms found at PubChem are:
Solanesol, 13190-97-1, Nonaisoprenol, Betulanonaprenol, UNII-FF31XTR2N4, FF31XTR2N4, CHEBI:26718, 3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol, (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol, 2,6,10,14,18,22,26,30,34-Hexatriacontanonaen-1-ol, 3,7,11,15,19,23,27,31,35-nonamethyl-, (2E,6E,10E,14E,18E,22E,26E,30E)-, SR-05000002169, Betulaprenol 9, C45H74O, AC1NUFXF, AC1Q7BUB, SCHEMBL182776, SPECTRUM1505325, (z,z,z,z,z,z,e,e)-amethyl, CHEMBL1567436, AFPLNGZPBSKHHQ-MEGGAXOGSA-N, MolPort-003-665-932, ZINC5273861, CS-025, CS0036, MFCD00070279, NSC299938, AKOS008901388, AC-4742, CCG-208614, NSC-299938, SDCCGMLS-0066857.P001, NCGC00095707-01, NCGC00095707-02, LS-75528, SC-17245, Solanesol from tobacco, >=90% (HPLC), W-2064, 190S971, A806330, I06-0563, SR-05000002169-2, SR-05000002169-3, (2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethyl-1-hexatriaconta-2,6,10,14,18,22,26,30,34-nonaenol, 111820-07-6, 2,10,14,18,22,26,30,34-Hexatriacontanonaen-1-ol, 3,7,11,15,19,23,27,31,35-nonamethyl-, (all-E)-, 28973-73-1, 3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonen-1-ol, 540-03-4

ID: 119

InChIKey: AFSDNFLWKVMVRB-UHFFFAOYSA-N
SMILES: C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281855
synonyms found at PubChem are:
ellagic acid, 476-66-4, Benzoaric acid, Lagistase, Eleagic acid, Alizarine Yellow, Elagostasine, 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, Ellagic acid dihydrate, Llagic acid, Acide ellagique, Acido elagico, Acidum ellagicum, C.I. 55005, Gallogen (VAN), Gallogen (astringent), C.I. 75270, Ellagate, Ellagic acid [INN:DCF], UNII-19YRN3ZS9P, Acido elagico [INN-Spanish], CCRIS 774, Gallogen, astringent, Acide ellagique [INN-French], Acidum ellagicum [INN-Latin], MLS000069632, C14H6O8, EINECS 207-508-3, NSC407286, NSC 407286, NSC 656272, BRN 0047549, 19YRN3ZS9P, CHEMBL6246, SMR000058244, CHEBI:4775, AFSDNFLWKVMVRB-UHFFFAOYSA-N, 2,3,7,8-Tetrahydroxy(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione, MFCD00006914, NSC656272, NCGC00017245-02, Diphenic acid, 4,4',5,5',6,6'-hexahydroxy-, di-delta-lactone, DSSTox_CID_557, (1)Benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-, DSSTox_RID_75657, DSSTox_GSID_20557, W-202834, 4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone, Pomegranate juice, [1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-, 2,3,7,8-Tetrahydroxy(1)benzopyrano(5,4,3-cde)-(1)benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, CAS-476-66-4, SR-01000721925, Benzoarate, Ellagsaeure, Elllagicacid, Polyphenolic, Eleagate, Ellagic, Llagate, Elagic Acid, HSDB 7574, 2zjw, REF, tetrahydroxy[?]dione, Spectrum_001194, Spectrum2_000905, Spectrum3_001535, Spectrum4_000750, Spectrum5_000959, D0A1CM, Oprea1_032884, SCHEMBL20429, BSPBio_002950, KBioGR_001080, KBioSS_001674, 5-19-07-00108 (Beilstein Handbook Reference), MLS006011868, BIDD:ER0482, BIDD:GT0565, SPECTRUM1502245, SPBio_000750, Ellagic acid, 476-66-4, BDBM4078, LTK-20, DTXSID2020557, SCHEMBL19184504, BCBcMAP01_000154, cid_5281855, KBio2_001674, KBio2_004242, KBio2_006810, KBio3_002450, BIE1001, Ellagic acid, analytical standard, MolPort-000-861-050, ZX-AFC000221, HMS1921N20, Pharmakon1600-01502245, BCP10830, HY-B0183, KS-00000G4Q, TNP00132, ZINC3872446, Tox21_110805, 6244AF, BBL009292, BS0259, CCG-36358, CE-039, NSC758198, s1327, SBB006501, STK801964, Ellagic acid, >=96.0% (HPCE), AKOS004120045, Tox21_110805_1, CS-2067, DB08846, EBD2138595, LS-1285, NSC-407286, NSC-656272, NSC-758198, SDCCGMLS-0066664.P001, SMP1_000111, NCGC00017245-01, NCGC00017245-03, NCGC00017245-04, NCGC00017245-05, NCGC00017245-06, NCGC00017245-07, NCGC00017245-08, NCGC00017245-09, NCGC00017245-10, NCGC00017245-12, NCGC00094975-01, NCGC00094975-02, NCGC00094975-03, NCGC00094975-04, NCGC00178375-01, AC-11647, AK162122, AN-45155, AS-35095, CC-27449, NCI60_003869, SC-17946, ST057073, SBI-0051742.P002, AB0073029, AB2000047, AX8127215, E0375, FT-0603405, H2736, ST24038499, C10788, MLS-0066664.0001, AB00052292_11, AB00052292_12, C-18851, I04-0032, SR-01000721925-3, SR-01000721925-4, SR-01000721925-5, SR-01000721925-6, SR-01000721925-7, BRD-K30466858-001-05-4, Ellagic acid, primary pharmaceutical reference standard, Ellagic acid, >=95% (HPLC), powder, from tree bark, Diphenic acid,4',5,5',6,6'-hexahydroxy-, di-.delta.-lactone, 2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione #, 4,4',5,5',6,6'-HEXAHYDROXYDIPHENIC ACID 2,6,2',6'-, Diphenic acid, 4,4',5,5',6,6'-hexahydroxy-, di-.delta.-lactone, [1]Benzopyrano[5,3-cde][1]benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-, 2,3,7,8-Tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 2,3,7,8-Tetrahydroxy[1]benzopyrano-[5,4,3-cde][1]benzopyran-5,10-dione, [1,2'-dicarboxylic acid, 4,4',5,5',6,6'-hexahydroxy-, di-.delta.-lactone, (1,1'-Biphenyl)-2,2'-dicarboxylic acid, 4,4',5,5',6,6'-hexahydroxy-, di-.delta.-lactone, 4,4 inverted exclamation marka,5,5 inverted exclamation marka,6,6 inverted exclamation marka-Hexahydroxydiphenic acid 2,6,2 inverted exclamation marka,6 inverted exclamation marka-dilactone, 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0;{4,16}.0;{11,15}]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione, 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione

ID: 120

InChIKey: AFVLVVWMAFSXCK-VMPITWQZSA-N
SMILES: C1=CC(=CC=C1/C=C(\C#N)/C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5328791
synonyms found at PubChem are:
alpha-cyano-4-hydroxycinnamic acid, 28166-41-8, alpha-Cyano, 2-Cyano-3-(4-hydroxyphenyl)acrylic acid, CHCA, alpha-CHCA, ACCA, (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid, 4-HCCA, CHEBI:64340, AFVLVVWMAFSXCK-VMPITWQZSA-N, (E)-2-cyano-3-(4-hydroxyphenyl)acrylic acid, 1-carboxy-1-cyano-2-(4-hydroxyphenyl)ethylene, (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid, CHC, alpha-CCA, 2-Propenoic acid, 2-cyano-3-(4-hydroxyphenyl)-, AC1NS5CM, AC1Q4QEL, Spectrum5_001633, AC1Q71LE, SCHEMBL26825, BSPBio_002260, MLS002207285, CHEMBL76602, BDBM4350, HMS500K21, MolPort-001-792-047, ZINC155109, CCG-39475, GEO-00838, IN2098, MFCD00004204, s8612, SBB057160, .alpha.-Cyano-4-hydroxycinnamic acid, AKOS000145566, IDI1_000219, NCGC00094622-01, NCGC00094622-02, alpha-Cyano-4-hydroxybenzenepropenoic acid, alpha-Cyano-4-hydroxycinnamic acid, 97%, alpha-Cyano-4-hydroxycinnamic acid, 99%, benzylidenemalononitrile (BMN) deriv. 34, SMR001306800, KB-117658, ST50997515, 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid, A819766, (E)-2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid, BRD-K60302405-001-02-9, BRD-K60302405-001-04-5, (2E)-2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid #, alpha-Cyano-4-hydroxycinnamic acid, >=98% (TLC), powder, alpha-Cyano-4-hydroxycinnamic acid, purum, >=99.0% (HPLC), alpha-Cyano-4-hydroxycinnamic acid, suitable for MALDI-TOF MS, alpha-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, >=99.0% (HPLC), alpha-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, Ultra pure

ID: 121

InChIKey: AFWKBSMFXWNGRE-ONEGZZNKSA-N
SMILES: CC(=O)/C=C/C1=CC(=C(C=C1)O)OC

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"G Li" "KL Kirk" "K Bernard" "W Wang"

CID is 5354238
synonyms found at PubChem are:
Dehydrozingerone, 1080-12-2, Feruloylmethane, 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)but-3-en-2-one, Vanillalacetone, Dehydro(O)-paradol, Vanillylidene acetone, MHSK, Dehydrogingerone, Vanylidenacetone, 3-BUTEN-2-ONE, 4-(4-HYDROXY-3-METHOXYPHENYL)-, (O)-Paradol, dehydro-, Vanillidene acetone, 3-Methoxy-4-hydroxybenzalacetone, (O)-Dehydroparadol, 4-Hydroxy-3-methoxystyryl methyl ketone, (E)-4-(4-hydroxy-3-methoxyphenyl)but-3-en-2-one, NSC 4019, NSC 5316, UNII-8CJX5I27B7, Vanillylideneacetone, 4-Hydroxy-3-methoxybenzylideneacetone, NSC 26613, NSC 44708, (0)-Dehydroparadol, FEMA No. 3738, Methyl-3-methoxy-4-hydroxy styryl ketone, NSC-4019, NSC-5316, EINECS 214-096-9, NSC 45411, NSC-44708, NSC-45411, BRN 2049660, Methyl-3-methoxy-4-hydroxystyryl ketone, AI3-01934, 8CJX5I27B7, CHEMBL106509, 22214-42-2, CHEBI:81361, Vanillylidenacetone, AFWKBSMFXWNGRE-ONEGZZNKSA-N, [0]-Dehydroparadol, (3E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-en-2-one, [0]-Paradol, dehydro-, dehydrozingerol, AE-562/43459152, W-200772, (E)-4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one, C11H12O3, 4-hydroxy-3-methoxybenzalacetone, MMHSK, 3-Buten-2-one,4-(4-hydroxy-3-methoxyphenyl)-, (E)-2-Methoxy-4-(3-oxo-1-butenyl)phenol, D05GRI, AC1NS57G, 2-08-00-00326 (Beilstein Handbook Reference), SCHEMBL498223, ZINC8046, DTXSID2061480, Vanillylidenacetone, >=98.5%, 3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)-, (E)-, NSC4019, NSC5316, MolPort-001-823-649, NSC26613, NSC44708, NSC45411, BDBM50195679, MFCD00012210, NSC-26613, AKOS004909556, DS-4905, FCH5479239, Vanillylidenacetone, analytical standard, AJ-08309, AK135171, AN-19685, BBV-38737560, LS-47310, ZB000663, AX8090618, KB-187080, TC-104629, ST24042954, C17840, 4-(4-Hydroxy-3-methoxy-phenyl)-but-3-en-2-one, 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one #, C-49429, I14-44563, (E)-4-(4-Hydroxy-3-methoxy-phenyl)-but-3-en-2-one

ID: 122

InChIKey: AGFVQCSHMSTFBV-UHFFFAOYSA-N
SMILES: C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt]

biological descriptors:

CFTR relevance: strong CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

CID is 498142
synonyms found at PubChem are:
carboplatin, Cbdca, NSC241240, Carboplatin (USAN), 1,1-Cyclobutanedicarboxylate diammine platinum(II), cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II), cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II), Platinum, diammine[1,1-cyclobutanedicarboxylato(2-)-O,O']-, (SP-4-2)-, 41575-94-4, 7,7-diamino-[?]spiro[3.5]nonane-5,9-dione, Platinum(II), (1, 1-cyclobutanedicarboxylato)diammine-, cis-, Platinum, {diammine[1,1-cyclobutanedicarboxylato(2-)-O,O']-,} (SP-4-2)-, Platinum, diamine(1, 1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)-, AC1LAYHA, azanide; cyclobutane-1,1-dicarboxylic acid; platinum

ID: 123

InChIKey: AGKRHAILCPYNFH-DUQSFWPASA-N
SMILES: CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5312331
synonyms found at PubChem are:
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid, DEDA, AGKRHAILCPYNFH-DUQSFWPASA-N, 89560-01-0, 5,8-Eicosadienoic acid, 7,7-dimethyl-, (Z,Z)-, 7,7-dimethyleicosadienoic acid, 7,7-dimethyl-5Z,8Z-eicosadienoic acid, (5Z,8Z)-7,7-Dimethylicosa-5,8-dienoic acid, 7,7-Dimethyl-eda, 7,7-Dimethyl-eicosadienoic acid, AC1NSMI1, Lopac-D-8008, BSPBio_001459, BML3-B09, SCHEMBL1319566, CHEMBL1323529, HMS1361I21, HMS1791I21, HMS1989I21, HMS3261M06, HMS3402I21, ZINC8034913, Tox21_500462, LMFA01020253, MFCD00133010, CCG-204554, LP00462, IDI1_033929, NCGC00015371-01, NCGC00015371-02, NCGC00015371-03, NCGC00015371-04, NCGC00015371-05, NCGC00015371-06, NCGC00015371-07, NCGC00093876-01, NCGC00093876-02, NCGC00093876-03, NCGC00093876-04, NCGC00093876-05, NCGC00261147-01, 7,7-dimethyl-(5z,8z)-eicosa-dienoic acid, EU-0100462, (Z,Z)-7,7-dimethyl-5,8-eicosadienoic acid, D 8008, SR-01000075833, 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid, >=95%, SR-01000075833-1, 5,8-Eicosadienoic acid, 7,7-dimethyl-, (5Z,8Z)-, BRD-K65207153-001-02-9

ID: 124

InChIKey: AGMMTXLNIQSRCG-UHFFFAOYSA-N
SMILES: CCC1NC2=CC(=C(C=C2C(=O)N1)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6307
synonyms found at PubChem are:
QUINETHAZONE, Chinethazonum, Quinethazon, Quinethazonum, Hydromox, Aquamox, Idrokin, 73-49-4, Chinetazone, Quinetazona, Chinetazone [DCIT], Quinetazona [INN-Spanish], Quinethazonum [INN-Latin], Quinethazone (aquamox), Chinethazone, CL 36010, Hydromox (TN), Quinethazone [INN:BAN:JAN], CCRIS 6098, HSDB 3392, EINECS 200-801-7, Quinethazone (JAN/INN), 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-sulfamoylquinazoline, 7-Chloro-2-ethyl-6-sulfamoyl-1,2,3,4-tetrahydro-4-quinazolinone, 6-Quinazolinesulfonamide, 7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-, 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamide, BRN 0818554, CHEBI:8717, 2-Ethyl-7-chloro-1,2,3,4-tetrahydro-4-oxochinazolin-6-sulfonamid, 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide, 7-chloro-2-ethyl-4-oxo-2,3-dihydro-1H-quinazoline-6-sulfonamide, DSSTox_CID_3548, DSSTox_RID_77074, DSSTox_GSID_23548, 6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-ethyl-4-oxo-, quimethazin, C10H12ClN3O3S, CAS-73-49-4, NCGC00016313-01, Quinethazone [USP:INN:BAN:JAN], Chinetazone[DCIT], Prestwick0_001050, Prestwick1_001050, Prestwick2_001050, Prestwick3_001050, D0J8ZA, AC1L1M8L, CHEMBL1532, BSPBio_000980, 5-25-09-00214 (Beilstein Handbook Reference), MLS002154126, SCHEMBL301310, SPBio_002910, BPBio1_001078, GTPL7289, DTXSID9023548, BDBM25898, AGMMTXLNIQSRCG-UHFFFAOYSA-N, HMS1571A22, HMS2098A22, HMS2234O04, HMS3370M01, HMS3715A22, Pharmakon1600-01503877, BCP07451, Tox21_110366, NSC759904, ZINC00000686, Tox21_110366_1, API0009172, CCG-213232, DB01325, LS-1624, NSC-759904, NCGC00179351-03, SMR001233433, AB00514022, FT-0674271, C07342, D00461, AB00514022_06, SR-01000841190, SR-01000841190-2, BRD-A59303141-001-03-9, 7-chloro-2-ethyl-4-hydroxy-1,2-dihydroquinazoline-6-sulfonamide, 2-Ethyl-7-chloro-1,2,3,4-tetrahydro-4-oxoquinazoline-6-sulfonamide, 7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinzaolinesulfonamide

ID: 125

InChIKey: AGNGYMCLFWQVGX-AGFFZDDWSA-N
SMILES: C([C@@H](C(=O)O)N)O/C(=C/[N+]#N)/[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5284344
synonyms found at PubChem are:
azaserine, Azaserin, O-Diazoacetyl-L-serine, 115-02-6, Diazoacetate (ester) L-serine, L-Serine, diazoacetate (ester), RCRA waste number U015, CCRIS 61, L-beta-(Diazoacetoxy)alanin, CL 337, L-azaserine, Azaserine [USAN:INN], Azaserinum [INN-Latin], HSDB 5093, Azaserina [INN-Spanish], CN 15757, Serine, diazoacetate (ester), L-, CN-15,757, P-165, Acetic acid, diazo-, ester with serine, UNII-87299V3Q9W, AI3-25016, NSC 742, NSC-742, EINECS 204-061-6, O-(diazoacetyl)-L-serine, RCRA waste no. U015, Azaserinum, Azaserina, MLS000028392, NSC742, AZS, 87299V3Q9W, SMR000058638, DSSTox_CID_118, DSSTox_RID_75380, DSSTox_GSID_20118, CAS-115-02-6, CHEBI:74846, Azeserine, NCGC00018164-02, Opera_ID_431, Azaserine (USAN/INN), AC1NR4AG, NCIMech_000844, SCHEMBL8861, Serine, diazoacetate (ester), L-serine, O-(diazoacetyl)-, Azaserine, >=98% (TLC), C5H8N3O4, CHEMBL442607, CHEMBL1095699, DTXSID9020118, LL-D05139a, MolPort-003-925-966, HMS2232J04, HY-B0919, Tox21_110833, Tox21_302892, CL-337, MFCD00036802, Tox21_110833_1, LS-7206, NCGC00021876-03, NCGC00021876-04, NCGC00256571-01, CN-15757, X6877, C19194, D03032, (2S)-2-amino-3-(2-diazoacetyl)oxy-propanoic acid, J-003178, (E)-1-[(2S)-2-amino-3-hydroxy-3-oxopropoxy]-2-diazonioethenolate, O-OOmicro feminineOOo pound>>u-L-E inverted question mark degrees +/-Ea, Azaserine, Hybri-Max(TM), gamma-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

ID: 126

InChIKey: AGOYDEPGAOXOCK-KCBOHYOISA-N
SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 84029
synonyms found at PubChem are:
clarithromycin, 81103-11-9, Biaxin, Clarithromycine, Klaricid, 6-O-Methylerythromycin, Clathromycin, 6-O-Methylerythromycin a, Abbott-56268, Macladin, Clarith, Kofron, Veclam, Clarithromycinum, Naxy, A-56268, Claritromicina, TE-031, Abbotic, Astromen, Bicrolid, Clacine, Clambiotic, Claribid, Claricide, Claridar, Claripen, Fromilid, Heliclar, Klaciped, Mabicrol, Clacee, Clacid, Clarem, Crixan, Cyllid, Klabax, Klarid, Klarin, Maclar, Helas, Mavid, Adel, Biaxin filmtab, Erythromycin, 6-O-methyl-, Klax, Biaxin HP, Biaxin xl filmtab, Klaricid Pediatric, Klacid, Vikrol, Clari, Infex, Biaxin XL, DRG-0099, UNII-H1250JIK0A, Clarithromycine [INN-French], Clarithromycinum [INN-Latin], Claritromicina [INN-Spanish], Zeclar, CHEBI:3732, H1250JIK0A, C38H69NO13, Klaricid H.P., CPD000466382, clarithromycina, Cyllind, Clarithromycin extended release, Klaricid XL, (14R)-14-Hydroxyclarithromycin, Klaricid H.P, TE031, Biaxin (TN), Clarithromycin [USAN:INN:BAN:JAN], (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione, CTY, SMR000466382, O(6)-methylerythromycin, SR-05000001992, Lactoferrin B & Clarithromycin, Lactoferrin H & Clarithromycin, Clarithromycin (Biaxin, Klacid), Clarithromycin & Interleukin-12, CLM & IL-12, ANX-015, clamicin, SDP-015, Clarithromycin suspension or tablets, CCRIS 8833, HSDB 8055, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione, Clarithromycin,(S), Spectrum_000089, Clarithromycin [USAN:USP:INN:BAN:JAN], SpecPlus_000559, 6-O-methyl erythromycin, 6-O-Methyl-erythromycin, CLA;, Spectrum2_001668, Spectrum3_001667, Spectrum4_000629, Spectrum5_001729, 6-0-methylerythromycin A, AC1L36NJ, CHEMBL1741, SCHEMBL38125, BSPBio_003453, KBioGR_001218, KBioSS_000509, MLS000759516, MLS001201751, MLS001424066, BIDD:GT0200, DivK1c_006655, SPECTRUM1504231, SPBio_001855, CHEMBL3764720, DTXSID3022829, KBio1_001599, KBio2_000509, KBio2_003077, KBio2_005645, KBio3_002673, AGOYDEPGAOXOCK-KCBOHYOISA-N, Clarithromycin (JP17/USP/INN), MolPort-002-507-425, Clarithromycin, >=95% (HPLC), Clarithromycin, >=98% (HPLC), HMS1922H09, HMS2051G18, HMS2090O11, HMS2094M05, HMS2231A08, HMS3715J17, Pharmakon1600-01504231, EBD13493, BDBM50404044, CCG-39086, LMPK04000014, MFCD00865140, NSC758704, s2555, ZINC85534098, C30H54O11.C9H19NO2, AKOS015894242, CS-2576, DB01211, LS-1812, MCULE-7168853332, NC00140, NSC-758704, NCGC00178054-01, CC-25899, H781, HY-17508, SAM001246748, SBI-0206716.P001, FT-0602940, C06912, D00276, J10130, AB00053394-10, AB00053394-12, AB00053394-13, AB00053394_14, AB00053394_15, 103C119, C-23486, Q-200870, SR-05000001992-1, SR-05000001992-2, BRD-K49668410-001-07-1, BRD-K49668410-001-18-8, Clarithromycin, European Pharmacopoeia (EP) Reference Standard, Clarithromycin, United States Pharmacopeia (USP) Reference Standard, Clarithromycin Identity, United States Pharmacopeia (USP) Reference Standard, Clarithromycin, Ready Made Solution, 50 mg/mL in DMSO, 0.2 mum filtered, Clarithromycin for peak identification, European Pharmacopoeia (EP) Reference Standard, Clarithromycin, Pharmaceutical Secondary Standard; Certified Reference Material, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

ID: 127

InChIKey: AGSOOCUNMTYPSE-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=C(C(=NO1)OCP(=O)(O)O)CC(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4615193
synonyms found at PubChem are:
ATPO, 252930-37-3, (R,S)-2-Amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid, 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-1,2-oxazol-4-yl]propanoic acid, ATPO, solid, AC1NECDZ, D03VBJ, Lopac0_000092, CHEMBL265301, GTPL4141, SCHEMBL4318475, DTXSID70404915, MolPort-003-940-289, HMS3260C06, HMS3261F20, Tox21_500092, Tox21_500589, MFCD03452828, CCG-204187, LP00092, LP00589, NCGC00015093-02, NCGC00015093-03, NCGC00015093-04, NCGC00015093-05, NCGC00093594-01, NCGC00093594-02, NCGC00260777-01, NCGC00261274-01, EU-0100092, A 7845, SR-01000075689, SR-01000075689-1, 2-Amino-3-[3-(phosphonomethoxy)-5-tert-butylisoxazole-4-yl]propionic acid

ID: 128

InChIKey: AGXVEALMQHTMSW-UHFFFAOYSA-N
SMILES: CN1C=C(N=C1)CCN.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957601
synonyms found at PubChem are:
1-Methylhistamine dihydrochloride, 6481-48-7, 2-(1-Methyl-1H-imidazol-4-yl)ethanamine dihydrochloride, 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochloride, EU-0100757, SCHEMBL1320841, CHEMBL1487156, AGXVEALMQHTMSW-UHFFFAOYSA-N, MolPort-004-946-867, KS-000019WB, Tox21_500757, MFCD00037000, 2-(1-Methylimidazole-4-yl)ethanamine, AKOS016367671, CCG-222061, LP00757, MCULE-1498707236, NCGC00094097-01, NCGC00261442-01, NS-01990, ST085498, AX8320530, CS-0046885, C-0263, M 4910, SR-01000075290, 1-Methyl-4-(|A-aminoethyl)imidazole dihydrochloride, 1-methyl-4-(2-aminoethyl)imidazole dihydrochloride, SR-01000075290-1, 1-Methyl-4-(beta-aminoethyl)imidazole dihydrochloride, 1-Methylhistamine dihydrochloride, >=98% (TLC), powder, [2-(1-methyl-1H-imidazol-4-yl)ethyl]amine dihydrochloride, 2(1-Methyl-1H-imidazol-4-yl)-ethylamine bis hydrochloride

ID: 129

InChIKey: AHLBNYSZXLDEJQ-FWEHEUNISA-N
SMILES: CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3034010
synonyms found at PubChem are:
orlistat, 96829-58-2, Tetrahydrolipstatin, Xenical, Alli, Orlipastat, (-)-Tetrahydrolipstatin, Orlipastatum, Orlipastatum [INN-Latin], THLP, tetrahydrolipastatin, Orlistat [USAN:INN], Ro-18-0647, Xenical (TN), UNII-95M8R751W8, C29H53NO5, Ro 18-0647/002, (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate, N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester, Orlistat (Alli, Xenical), MLS002207022, CHEMBL175247, [(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-4-methylpentanoate, N-Formyl-L-leucine, ester with (3S,4S)-3-hexyl-4-((2S)-2-hydroxytridecyl)-2-oxetanone, 95M8R751W8, KS-1183, SMR000466339, R-212, Ro 18-0647/008, L-Leucine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, (2S-(2alpha(R*),3beta))-, (S)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl formyl-L-leucinate, L-Leucine,N-formyl-, (1S)-1-(((2S,3S)-3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, [(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-oxetan-2-yl]methyl]dodecyl] (2S)-2-formamido-4-methyl-pentanoate, L-Leucine, N-formyl-, (1S)-1-(((2S,3S)-3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, SR-01000759417, orlistatum, Orlistat [USAN:INN:BAN], HSDB 7556, N-formyl-L-leucine (1S)-1-{[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl}dodecyl ester, zlchem 13, Alli (TN), AC1MHWQP, PubChem18271, Roche brand of orlistat, Orlistat (USAN/INN), Orlistat,Tetrahydolipstat, (-)-tetrahydrolipostatin, D0T9TJ, Orlistat, >=98%, solid, SCHEMBL16408, Orlistat (JAN/USAN/INN), MLS000759448, MLS001423955, BIDD:GT0853, GTPL5277, LEU002, DTXSID8023395, BDBM24567, CHEBI:94686, AOB6737, GlaxoSmithKline brand of orlistat, ZLA0015, AHLBNYSZXLDEJQ-FWEHEUNISA-N, L-Leucine, N-formyl-, (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester, MolPort-005-938-035, HMS2051I08, HY-B0218, THL, ZINC8214635, Hoffmann-La Roche brand of orlistat, MFCD05662360, s1629, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate, AKOS015894875, BCP9001031, CCG-100851, CS-2165, DB01083, NC00101, RL06088, NCGC00165856-01, NCGC00165856-02, AN-15658, BC214880, CPD000466339, SAM001246637, SC-16265, BCP0726000044, Tetrahydrolipstatin|||Ro 18-0647/002, AB1009256, LS-178328, Ro-180647002, Alli, Xenical, Tetrahydrolipstatin, Orlistat, FT-0082584, FT-0601570, O0381, Ro-180647-002, ST24048848, Ro-18-0647/002, D04028, J90006, AB00639987-09, AB00639987_10, 829O582, Q-201519, SR-01000759417-5, SR-01000759417-7, Z2379810072, Orlistat, United States Pharmacopeia (USP) Reference Standard, Orlistat, Pharmaceutical Secondary Standard; Certified Reference Material, (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl N-formyl-L-leucinate, 2-formamido-3-[(3-hexyl-4-oxo-oxetan-2-yl)methyl]-2-isobutyl-tetradecanoate, N-formyl-L-leucine (S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester, N-formyl-L-leucine-(S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-dodecyl ester, (-)-Tetrahydrolipstatin; N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl] dodecyl ester; Ro-18-0647, (2S)-2-formamido-4-methylpentanoic acid [(2S)-1-[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]tridecan-2-yl] ester, (S)-((S)-1-((2S,3S)-3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl) 2-formamido-4-methylpentanoate, 111397-16-1

ID: 130

InChIKey: AHLHZSCENKUUSF-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

CID is 5397276
synonyms found at PubChem are:
7-hydroxy-3-(2-methoxyphenyl)-4H-chromen-4-one, 63909-40-0, 7-hydroxy-2'-methoxyisoflavone, 7-hydroxy-3-(2-methoxyphenyl)chromen-4-one, 4H-1-Benzopyran-4-one, 7-hydroxy-3-(2-methoxyphenyl)-, EN300-37034, KBio2_001215, Spectrum_000735, SpecPlus_000115, Spectrum2_000598, Spectrum3_000688, Spectrum4_001613, Spectrum5_000365, AC1NU9H2, Oprea1_731203, BSPBio_002415, KBioGR_001985, KBioSS_001215, SPECTRUM201309, DivK1c_006211, SCHEMBL234467, SPBio_000476, AC1Q450X, CHEMBL575073, CTK2A7983, KBio1_001155, KBio2_003783, KBio2_006351, KBio3_001635, DTXSID80419858, AHLHZSCENKUUSF-UHFFFAOYSA-N, CHEBI:108602, MolPort-000-424-538, ALBB-017540, BB_NC-03144, ZINC5729882, ZX-AN016227, BBL034746, CCG-39150, SBB042190, STK888282, AKOS000270914, 7-HYDROXY-2;-METHOXYISOFLAVONE, MCULE-3582068908, NCGC00095822-01, NCGC00095822-02, NCGC00178663-01, R2592, ST50039226, 7-hydroxy-3-(2-methoxy-phenyl)-chromen-4-one, AB00052652-03, BRD-K09203354-001-02-4, F0850-4769

ID: 131

InChIKey: AHSKLSFFKJHWAI-RGMNGODLSA-N
SMILES: CN(C)C(=NCCC[C@@H](C(=O)O)N)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9964741
synonyms found at PubChem are:
N^G,N^G-Dimethylarginine hydrochloride, 65005-57-4, EU-0100388, N',N'-Dimethylarginine HCl, MLS000860005, CHEMBL1255836, asym-Dimethylarginine hydrochloride, Tox21_500388, CCG-221692, LP00388, N;G,N;G-Dimethylarginine hydrochloride, NCGC00093816-01, NCGC00261073-01, SMR000326864, D 4268, SR-01000075489, NG,NG'-DIMETHYL-L-ARGININE, DIHYDROCHLORIDE, SR-01000075489-1

ID: 132

InChIKey: AHVKNBRJVKCGKJ-UHFFFAOYSA-N
SMILES: CC1(C2C1CC(C(C2)O)(C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 89242
synonyms found at PubChem are:
carane-3,4-diol, 3,4-DIHYDROXYCARANE, 3,7,7-trimethylbicyclo[4.1.0]heptane-3,4-diol, 57526-47-3, 19898-58-9, 19898-59-0, 19898-60-3, 3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, SPBio_001682, 22556-08-7, 57457-02-0, EINECS 243-414-9, EINECS 243-415-4, EINECS 243-417-5, EINECS 243-418-0, EINECS 245-075-2, EINECS 260-745-4, EINECS 260-788-9, trans-3,4-caranediol, AC1L3HFY, Spectrum2_001701, Spectrum3_001142, Spectrum4_001992, AC1Q77XI, SCHEMBL76167, BSPBio_002663, KBioGR_002551, SPECTRUM1505274, CHEMBL3039109, CTK0I1170, KBio3_002163, AHVKNBRJVKCGKJ-UHFFFAOYSA-N, 3,7,7-trimethylnorcarane-3,4-diol, CCG-38783, (1alpha,3alpha,4beta,6alpha)-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, (1alpha,3beta,4alpha,6alpha)-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, (1alpha,3beta,4beta,6alpha)-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, AKOS006272464, SDCCGMLS-0066905.P001, (1alpha,3alpha,4alpha,6alpha)-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, (1S-(1alpha,3alpha,4alpha,6alpha))-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, (1S-(1alpha,3beta,4alpha,6alpha))-3,7,7-Trimethylbicyclo(4.1.0)heptane-3,4-diol, NCGC00095704-01, NCGC00095704-02, 19898-61-4, 4,7,7-trimethylbicyclo[4.1.0]heptane-3,4-diol, SR-05000002403, SR-05000002403-1

ID: 133

InChIKey: AIFRHYZBTHREPW-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=C(N2)C=NC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 64961
synonyms found at PubChem are:
9H-Pyrido[3,4-B]indole, Norharman, Norharmane, 244-63-3, beta-Carboline, 2,9-Diazafluorene, Carbazoline, 9H-Beta-carboline, 2-Azacarbazole, 9H-Pyrido(3,4-B)indole, .beta.-Carboline, Carbazoline (VAN), b-carboline, beta Carboline, UNII-94HMA1I78O, CCRIS 6915, CHEBI:109895, EINECS 205-959-0, NSC 84417, 2H-Pyrido[3,4-b]indole, BRN 0128414, MLS000069651, 94HMA1I78O, CHEMBL275224, AIFRHYZBTHREPW-UHFFFAOYSA-N, SMR000058207, N-8700, N-8720, SR-01000000213, 9h-|A-carboline, Prestwick_363, Norharmane, 98%, zlchem 788, Norharman, free base, Norharmane crystalline, 9H-Beta-carboline #, Norharmane, crystalline, Kinome_3628, Spectrum_001132, ACMC-209gcg, Opera_ID_1385, Spectrum2_000588, Spectrum3_000741, Spectrum4_001915, Spectrum5_000630, DSSTox_CID_1070, D0R6FJ, Epitope ID:140123, AC1L22AW, AC1Q1IP5, DSSTox_RID_75928, NCIOpen2_001217, DSSTox_GSID_21070, SCHEMBL25834, BSPBio_002322, KBioGR_002537, KBioSS_001612, 5-23-08-00220 (Beilstein Handbook Reference), cid_64961, MLS001148623, SPBio_000436, GTPL8222, DTXSID2021070, 7259-44-1 (hydrochloride), CTK1A3451, CTK1A4855, KBio2_001612, KBio2_004180, KBio2_006748, KBio3_001542, KS-00000GHL, WLN: T B656 EN HMJ, ZINC66039, ZLD0247, 2-Hydro-9-dehydro-beta-carboline, MolPort-000-141-389, norharman hydrochloride monohydrate, 244-63-3 (Free base)., HMS2233G10, HMS3369E13, ACT06124, BCP20998, NSC84417, Tox21_200083, 1835AB, ANW-25454, BDBM50013811, CCG-38511, GL5091, MFCD00004956, NSC-84417, AKOS015969732, AKOS030537604, ACN-025078, CS-W008566, FCH1118646, LS-7625, MCULE-7379210172, SDCCGMLS-0003278.P003, TRA0037783, VZ23038, SMP2_000349, NCGC00018245-01, NCGC00018245-02, NCGC00018245-03, NCGC00018245-04, NCGC00018245-05, NCGC00018245-06, NCGC00021302-03, NCGC00021302-04, NCGC00257637-01, AK-25655, CAS-244-63-3, CC-08267, DS-10932, KB-47000, AX8013633, DB-046456, TC-114199, FT-0610769, P1121, ST50307983, VU0239493-6, A-8921, C20157, C-05041, SR-01000000213-3, SR-01000000213-4, BRD-K47467075-001-02-7, BRD-K47467075-001-03-5, BRD-K47467075-001-13-4, InChI=1/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13, 244-66-6, NRH

ID: 134

InChIKey: AIKVCUNQWYTVTO-UHFFFAOYSA-N
SMILES: CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 41114
synonyms found at PubChem are:
NICARDIPINE HYDROCHLORIDE, 54527-84-3, Nicardipine HCl, Cardene, Perdipine, Nicodel, Loxen, Angioglebil, Bionicard, Nicardil, Perdipina, Lincil, Dafil, Dagan, YC-93, Cardene SR, Nicardipine (Hydrochloride), RS-69216-XX-07-0, YC 93, EINECS 259-198-4, Nicardipine hydrochloride [USAN:JAN], RS-69216, MLS000069782, Perpidine, SMR000058487, 2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylatemonohydrochloride, 2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride, 3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, 69441-18-5, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester, monohydrochloride, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester, monohydrochloride, 3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, CPD004727071, SR-01000075333, Nerdipine, nicardipine;, CCRIS 8508, 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride, Prestwick_590, EINECS 274-007-4, YC-93 hydrochloride, Opera_ID_357, Cardene In 4.8% Dextrose In Plastic Container, Cardene In 5.0% Dextrose In Plastic Container, CAS-54527-84-3, DSSTox_CID_26992, DSSTox_RID_82040, DSSTox_GSID_46992, SCHEMBL41845, MLS001146898, MLS002153279, MLS002153794, C25H27N3O6.HCl, Nicardipine hydrochloride,(S), SPECTRUM1501135, AC1L253M, AC1Q67X4, CHEBI:7551, Cardene In 0.83% Sodium Chloride In Plastic Container, Cardene In 0.86% Sodium Chloride In Plastic Container, CHEMBL1200326, CHEMBL3199626, DTXSID9046992, CTK2F3563, AIKVCUNQWYTVTO-UHFFFAOYSA-N, MolPort-003-666-362, HMS1569M07, HMS1921H21, Pharmakon1600-01501135, BCP05610, EBD48801, Tox21_301832, Tox21_500809, ANW-42546, CCG-39033, HY-12515A, MFCD00057327, NSC757855, s4181, TN-901, AKOS015994734, BCP9000988, CS-3684, KS-1276, LP00809, NC00578, NE54503, NSC-757855, RS-69216-XX-07-O, Nicardipine hydrochloride (JP17/USAN), NCGC00094142-01, NCGC00094142-02, NCGC00094142-03, NCGC00094142-04, NCGC00094142-05, NCGC00256289-01, NCGC00261494-01, 2-(Benzyl(methyl)amino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride, AN-40518, BC201356, SAM002564254, SAM002643513, Nicardipine hydrochloride, powder, >=98%, LS-131264, TR-019279, EU-0100809, FT-0082866, FT-0630671, N0635, D00617, N 7510, 527N843, A830225, SR-01000075333-1, SR-01000075333-5, W-105615, 4- ?CHLORO- DIFLUORO- METHOXY) ? PHENYLAMINE, Nicardipine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Nicardipine for system suitability, European Pharmacopoeia (EP) Reference Standard, Nicardipine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 1,4-Dihydro-2,6-dimethyl-4-[3-nitrophenyl]methyl-2-[methyl- (phenyl-methl)amino]-3,5- pyridinedicarboxylic acid ethyl ester, 1,4-Dihydro-2,6-dimethyl-4-[3-nitrophenyl]methyl-2-[methyl-(phenyl-methl)amino]-3,5-pyridinedicarboxylic acid ethyl ester, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[2-[methyl-(phenylmethyl)amino]ethyl] ester hydrochloride, 2-(benzyl-methyl-amino)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, 2-(benzylmethylamino)ethl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride, 2-(N-benzyl-N-methylamino)ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, 2-[benzyl(methyl)amino]ethyl-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylathydrochlorid, 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester, hydrochloride (1:1), 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, O3-methyl O5-[2-[methyl-(phenylmethyl)amino]ethyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, O5-[2-[benzyl(methyl)amino]ethyl] O3-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride, AKOS015896566, I06-2345

ID: 135

InChIKey: AIONOLUJZLIMTK-AWEZNQCLSA-N
SMILES: COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 72281
synonyms found at PubChem are:
hesperetin, 520-33-2, Hesperitin, 3',5,7-Trihydroxy-4'-methoxyflavanone, YSO2, Cyanidanon 4'-methyl ether 1626, 5,7,3'-Trihydroxy-4'-methoxyflavanone, (-)-hesperetin, NSC 57654, Prestwick_908, UNII-Q9Q3D557F1, (S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, EINECS 208-290-2, CHEBI:28230, AIONOLUJZLIMTK-AWEZNQCLSA-N, Q9Q3D557F1, TNP00238, (S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one, (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-, Flavanone, 3',5,7-trihydroxy-4'-methoxy- (VAN) (8CI), (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chroman-4-one, (S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, Hesperitine, NSC-57654, (+-)-Hesperetin, (+/-)-Hesperetin, Spectrum_000181, (-)-(S)-hesperetin, AC1L2HRS, AC1Q6KIN, Prestwick0_000124, Prestwick1_000124, Prestwick2_000124, Prestwick3_000124, Spectrum2_001793, Spectrum3_001104, Spectrum4_001935, Spectrum5_000683, D07MGA, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, Oprea1_828704, SCHEMBL39833, BSPBio_000168, BSPBio_002808, KBioGR_002311, KBioSS_000661, SPECTRUM310012, MLS002154205, BIDD:ER0512, DivK1c_001039, SPBio_001745, SPBio_002107, BPBio1_000186, CHEMBL399121, DTXSID4022319, BCBcMAP01_000087, BDBM23418, HMS503O19, KBio1_001039, KBio2_000661, KBio2_003229, KBio2_005797, KBio3_002028, ZINC39092, MolPort-003-665-801, NINDS_001039, HMS1568I10, HMS2095I10, HMS2230M09, HMS3649H22, BCP28273, HY-N0168, KS-00000KM5, CCG-38441, LMPK12140003, MFCD00075646, s2308, SBB005936, AKOS016339567, AC-7970, AN-8453, DB01094, KS-5307, SDCCGMLS-0066605.P001, ACM41001905, IDI1_001039, SMP1_000148, 4'-Methoxy-3',5,7-trihydroxyflavanone, NCGC00016482-01, NCGC00016482-02, NCGC00016482-03, NCGC00016482-04, NCGC00142415-01, NCGC00142415-02, 5,7, 3'-Trihydroxy-4'-methoxyflavanone, AK327599, CAS-520-33-2, SMR001233491, ST055624, ZB001080, LS-185786, FT-0626940, N1856, C01709, Hesperetin, disposable screening library format, Flavanone, 3',5,7-trihydroxy-4'-methoxy-(VAN), SR-01000946723, Flavanone, 3',5,7-trihydroxy-4'-methoxy- (VAN), SR-01000946723-1, BRD-K30553453-001-05-8, BRD-K30553453-001-08-2, Flavanone, 3',5, 7-trihydroxy-4'-methoxy- (VAN), Flavanone, 3',5,7-trihydroxy-4'-methoxy-(VAN) (8CI), (2s)-5,7-Dihydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-2,3-Dihydro-4h-1-Benzopyran-4-One, (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one, 4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-, (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one (Hesperetin), 41001-90-5, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)- (9CI), 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-(9CI), 6JP

ID: 136

InChIKey: AIUDLVZBVMKUOQ-UHFFFAOYSA-N
SMILES: C(C1=CC(C2=CC=CC=C2)=CS1)1C(C(=O)OCC2=CC=CC=C2)=C(C)NC(C)=C1C(=O)OCC1=CC=CC=C1

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Giampieri" "M Mazzei" "M Zacchigna" "P Fossa" "F Cateni" "LJ Galietta" "MT Mazzei" "N Pedemonte"

CID is 46227418
synonyms found at PubChem are:
CHEMBL603629

ID: 137

InChIKey: AIXAANGOTKPUOY-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CCOC(=O)N.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5831
synonyms found at PubChem are:
carbachol, Carbamoylcholine chloride, 51-83-2, CARBACHOL CHLORIDE, Carbacholine, Carbocholine, Jestryl, Doryl, Carbamylcholine chloride, Miostat, Isopto Carbachol, Choline carbamate chloride, Carbacholin, Carbacholum, Carbacolina, Carbamiotin, Carbocholin, Carbochol, Carcholin, Coletyl, Vasoperif, Carbyl, Lentin, Moryl, Carbacholine chloride, Choline chlorine carbamate, Carbacol, Karbachol, Rilentol, Choline chloride, carbamate, Mistura C, Doryl (pharmaceutical), Carbaminocholine chloride, P. V. Carbachol, (2-Carbamoyloxyethyl)trimethylammonium chloride, Carbaminoylcholine chloride, Carbacholinum, Carbach, (2-Hydroxyethyl)trimethylammonium chloride carbamate, Karbamoylcholin chlorid, Carbamoylcholine-hydrochloride, Lentine [French], Karbachol [Czech], (2-Hydroxyethyl)trimethyl ammonium chloride carbamate, Carbacolo [DCIT], Lentine, Carbacholum chloratum, Carbachol hydrochloride, Carbacholini chloridum, Choline chloride, carbamoyl-, Doryl (VAN), Carbacholinium chloratum, Carbacol [INN-Spanish], Carbacholum [INN-Latin], Choline, chloride carbamate(ester), Carbamoylcholine (chloride), Carbacolo, 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminum chloride, 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride, Karbamoylcholin chlorid [Czech], gamma-Carbamoyl choline chloride, UNII-8Y164V895Y, Carbamic acid, ester with choline chloride, HSDB 6373, 2-(trimethylazaniumyl)ethyl carbamate chloride, EINECS 200-127-3, NSC 32865, TL 457, Choline, chloride, carbamate, hydrochloride, CHEBI:3385, Choline chloride carbamate, Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride, Carbachol [INN:BAN:JAN], Choline, chloride, carbamate, 2-(carbamoyloxy)-N,N,N-trimethylethanaminium chloride, 8Y164V895Y, Ethanaminium, 2-(aminocarbonyl)oxy-N,N,N-trimethyl-, chloride, Miostat (TN), Carbastat intraocular, DSSTox_CID_2730, 2-carbamoyloxyethyl(trimethyl)ammonium chloride, DSSTox_RID_76703, DSSTox_GSID_22730, CHEMBL14, Carbachol (JAN/USP/INN), CB, 2-(trimethylamino)ethyl aminooate, chloride, 2-carbamoyloxyethyl(trimethyl)azanium;chloride, CAS-51-83-2, SR-01000075312, NCGC00163219-01, 2-carbamoyloxyethyl(trimethyl)azanium chloride, 2-[(aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride, C 4382, C-1770, C6H15N2O2.Cl, Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride (1:1), Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1), (2-Carbamoyloxy-ethyl)-trimethyl-ammonium(Carbachol), Carbachol [USP:INN:BAN:JAN], Carbachol,(S), Choline, carbamate, Prestwick_1036, AC1LAVH8, AC1L1L8K, SCHEMBL2791, MLS002153502, SPECTRUM1500158, Carbamoylcholine chloride, 99%, DTXSID9022730, HMS502E07, Choline, carbamate, hydrochloride, MolPort-003-666-136, .gamma.-Carbamoyl choline chloride, HMS1570P21, HMS1920I15, HMS2091O17, HMS2097P21, HMS2236L04, HMS3260B08, HMS3372G03, HMS3714P21, Pharmakon1600-01500158, HY-B1208, NSC32865, Tox21_112029, Tox21_500243, CCG-38913, MFCD00012011, NSC-32865, NSC755919, SBB057998, AKOS015909565, AKOS025149486, Tox21_112029_1, CS-4836, DB00411, LP00243, MCULE-9644162883, NE31544, NSC-755919, WLN: ZVO2K1&1&1 &Q &G, NCGC00015237-07, NCGC00093705-01, NCGC00093705-02, NCGC00093705-03, NCGC00093705-04, NCGC00093705-05, NCGC00260928-01, AN-41622, KB-48668, LS-53194, SMR000058584, B7196, C0596, EU-0100243, FT-0623453, ST51007309, D00524, 31325-EP2274983A1, 31325-EP2277875A2, 31325-EP2284157A1, 31325-EP2289483A1, 31325-EP2299326A1, 31325-EP2305652A2, 31325-EP2305672A1, 31325-EP2308858A1, 31325-EP2311816A1, 31325-EP2311817A1, 2-aminocarbonyloxyethyl(trimethyl)azanium chloride, A828807, SR-01000075312-1, SR-01000075312-3, SR-01000075312-6, I14-31868, Z1551429748, 2-(carbamoyloxy)-N,N,N-trimethylethan-1-aminium chloride, Carbachol, European Pharmacopoeia (EP) Reference Standard, Carbamoylcholine chloride, >=98% (titration), crystalline, Carbachol, United States Pharmacopeia (USP) Reference Standard, Carbachol, Pharmaceutical Secondary Standard; Certified Reference Material, 16628-EP2280006A1, 16628-EP2281563A1, 16628-EP2281813A1, 16628-EP2295437A1, 16628-EP2298775A1, 16628-EP2311823A1, 16628-EP2316459A1

ID: 138

InChIKey: AJBBEYXFRYFVNM-UHFFFAOYSA-N
SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6603931
synonyms found at PubChem are:
MRS 1754, 264622-58-4, MRS-1754, MRS1754, CHEMBL273807, [3H]MRS1754, [3H]-MRS1754, N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide, N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide, NCGC00015689-01, Lopac-M-6316, D01QYQ, D0NE5P, ATL-GW-8, Lopac0_000729, GTPL449, GTPL453, ATL-GW-22, MLS002153324, AC1O7G54, SCHEMBL1222380, CHEBI:93269, CTK8E7916, AOB5542, ATL-618, ATL-844, DTXSID80424967, AJBBEYXFRYFVNM-UHFFFAOYSA-N, MolPort-023-276-567, HMS2230A06, HMS3268F13, HMS3373J21, ZINC4475274, BDBM50086170, AKOS024457276, AKOS027427086, CCG-204814, EX-3306, NCGC00015689-02, NCGC00015689-03, NCGC00015689-04, NCGC00094075-01, NCGC00094075-02, NCGC00094075-03, SMR001230737, B7173, EU-0100729, M 6316, L000415, SR-01000076213, J-016440, SR-01000076213-1, BRD-K72024482-001-01-3, A2B adenosine receptor antagonists, Adenosine/Ortho-McNeil, A2B adenosine receptor antagonists (oral, asthma/diabetes), Clinical Data, 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine, A2B adenosine receptor antagonists (oral, asthma/diabetes), Adenosine Therapeutics, (4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester, Acetamide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-, N-(4-Cyano-phenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide, N-(4-Cyano-phenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide(MRS-1754), N-(4-cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide

ID: 139

InChIKey: AJFJKGLXKPEJMU-UHFFFAOYSA-N
SMILES: C1CC2C3CCC(C2NC1)C4N3CCC5=C4NC6=CC=CC=C56.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6419917
synonyms found at PubChem are:
Nitrarine dihydrochloride, Prestwick_179, SR-05000002299, HMS1570I11, CCG-208364, SR-05000002299-3

ID: 140

InChIKey: AJLFOPYRIVGYMJ-INTXDZFKSA-N
SMILES: CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 64715
synonyms found at PubChem are:
Mevastatin, compactin, 73573-88-3, ML-236B, Mevastatinum, Mevastatina, Mevastatine, Mevastatinum [INN-Latin], Antibiotic ML 236B, Mevastatin [INN], CS 500, Compactin (penicillium), Mevastatine [INN-French], UNII-1UQM1K0W9X, Mevastatina [INN-Spanish], ML 236 B, CCRIS 4505, 1UQM1K0W9X, CHEMBL54440, CHEBI:34848, [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate, Mevastatin (Compactin), ML236B, 7-(1,2,6,7,8,8a-Hexahydro-2-methyl-8-(2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide, 6-demethylmevinolin, (1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthyl (S)-2-methylbutyrate, (S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate, Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-, Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha(R*),7-beta,8-beta(2S*,4S*),8a-beta))-, SMR000336944, kompaktin, Mevastatin,, ML 236B, NCGC00095942-01, AC1Q5WYM, D0J9GD, EC 700-442-0, AC1L21SK, SCHEMBL1116, DSSTox_CID_20684, DSSTox_RID_79540, DSSTox_GSID_40684, Lopac0_000754, MLS000721804, MLS000759452, MLS001424284, MLS002207227, GTPL3031, DTXSID4040684, Mevastatin, >=96% (HPLC), CTK8B3049, AJLFOPYRIVGYMJ-INTXDZFKSA-N, MolPort-002-885-840, MolPort-003-849-214, HMS2052P07, HMS2089D10, HMS2232N09, HMS3262G10, HMS3268A19, HMS3713B06, 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(compactin), 58948-09-7, Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-, KS-00000XT7, ZINC3833876, Tox21_111540, Tox21_500754, ANW-41687, BDBM50011036, BG0377, CS-500, MFCD05662341, s4223, AKOS015994712, Mevastatin, >=95% (HPLC), powder, CCG-101174, CS-1234, DB06693, KS-1085, LP00754, NC00424, SMP1_000077, NCGC00025202-04, NCGC00261439-01, (1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate, CPD000336944, HY-17408, I518, LS-46360, SAM001246644, SC-11548, AB0013739, CAS-73573-88-3, TR-023864, B1788, EU-0100754, M2275, C13963, M 2537, W-5323, AB00588266-06, AB00588266-08, AB00588266_09, 573M883, SR-01000729493, L-637312, SR-01000729493-4, BRD-K94441233-001-03-1, BRD-K94441233-001-17-1, Compactin, 6-Demethylvevinolin, CS-500, ML-236 B, (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, (S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate, (S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester, 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester, 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin), 60478-65-1

ID: 141

InChIKey: AJNMXMZCRHTBEH-UHFFFAOYSA-N
SMILES: CC1=C(C2=CC=CC=C2N1)CN(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 181513
synonyms found at PubChem are:
2-Methyl-3-N,N-dimethylaminomethylindole, 37125-92-1, 2-methylgramine, N,N-dimethyl-1-(2-methyl-1H-indol-3-yl)methanamine, 2-METHYL GRAMINE, 1H-Indole-3-methanamine, N,N,2-trimethyl-, dimethyl-(2-methyl-1h-indol-3-ylmethyl)-amine, M-3695, dimethyl[(2-methyl-1H-indol-3-yl)methyl]amine, Q-102919, NSC24942, NSC 24942, PubChem15856, Spectrum_000945, SpecPlus_000124, AC1Q3WMK, Spectrum2_000690, Spectrum3_000122, Spectrum4_000936, Spectrum5_000574, BSPBio_001764, KBioGR_001492, KBioSS_001425, SPECTRUM100599, DivK1c_006220, SPBio_000819, SCHEMBL2519973, CHEMBL1354316, CTK8F4407, KBio1_001164, KBio2_001425, KBio2_003993, KBio2_006561, KBio3_000924, AJNMXMZCRHTBEH-UHFFFAOYSA-N, MolPort-001-811-502, ZINC394962, AC1L4965, CCG-40024, CM-675, FCH916393, NSC-24942, STL442633, AKOS006229954, AC-6733, AN-9703, MCULE-4516162416, SDCCGMLS-0066311.P001, VI30167, NCGC00095442-01, NCGC00095442-02, AJ-21469, KB-25294, NS-01723, SC-21424, 1H-Indole-3-methanamine,N,N,2-trimethyl-, AB0073138, AX8014117, A6379, FT-0639361, A-1851, 125M921, C-07837, SR-05000002423, SR-05000002423-1, BRD-K50054100-001-03-4

ID: 142

InChIKey: AKJDEXBCRLOVTH-UHFFFAOYSA-N
SMILES: CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 90010
synonyms found at PubChem are:
Carbetapentane citrate, Pentoxyverine citrate, 23142-01-0, Loucarbate, Pentoxiverine citrate, Carbetapentane citrate salt, Toclase, Toclase citrate, Carbetapentone citrate, Carbetapentane (citrate), UNII-4SH0MFJ5HJ, Carbetapentane citrate [NF], EINECS 245-449-5, 4SH0MFJ5HJ, 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentanecarboxylate citrate, 2-(2(Diethylamino)ethoxy)ethyl 1-phenyl-cyclopentanecarboxylate citrate (1:1), 2-(2-(Diethylamino)ethoxy)ethyl 1-phenylcyclopentyl-1-carboxylate dihydrogen citrate, Ethanol, 2-(2-(diethylamino)ethoxy)-, 1-phenylcyclopentanecarboxylate (ester) citrate, W-107426, 2-(2-(Diethylamino)ethoxy)ethyl 1-phenylcyclopentanecarboxylate citrate (1:1), 1-Phenyl-cyclopentanecarboxylic acid 2-[2-(Diethylamino)ethoxy]ethyl ester citrate, 1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate salt, Cyclopentanecarboxylic acid, 1-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl ester, citrate (1:1), Diethyl(2-(2-((1-phenylcyclopentyl)formyloxy)ethoxy)ethyl)ammoniumdihydrogen 2-hydroxypropane-1,2,3-tricarboxylate, SR-01000075435, Atussil Citrate, Astomatop (TN), 2-(2-(diethylamino)ethoxy)ethyl 1-phenylcyclopentanecarboxylate 2-hydroxypropane-1,2,3-tricarboxylate, Prestwick_748, Caretapentane Citrate, Lopac-C-4662, Pentoxyverine citrate,(S), AC1L3J2X, MLS000859895, MLS002207180, SCHEMBL160096, SPECTRUM1501129, Pentoxyverine citrate (JP17), AC1Q68D8, CHEMBL1256696, CHEBI:31352, CTK8F8456, HMS501B18, KS-00000XMF, DTXSID10177717, MolPort-003-666-361, HMS1569M15, HMS1921H13, HMS2092F03, HMS2096M15, HMS2233B06, HMS3260P08, HMS3266A18, HMS3370A07, HMS3713M15, Pharmakon1600-01501129, BCP13538, HY-B1055, Tox21_500313, BN0126, CCG-39029, MFCD00055697, NSC757833, AKOS015899622, AN-7038, CS-4577, LP00313, NSC-757833, NCGC00016128-01, NCGC00016128-02, NCGC00016128-03, NCGC00016128-04, NCGC00016128-05, NCGC00017090-01, NCGC00093760-01, NCGC00093760-02, NCGC00093760-03, NCGC00260998-01, AC-19682, AK115683, AS-35372, LS-57907, AX8119983, CAS-23142-01-0, KB-279711, EU-0100313, FT-0630493, ST24048885, C 4662, D01260, 077P236, A839013, C-23076, SR-01000075435-1, SR-01000075435-3, SR-01000075435-5, SR-01000075435-7, SR-01000075435-8, I14-11705, SR-01000075435-11, 1-Phenylcyclopentane-1-carboxylic Acid Diethylaminoethoxyethyl Ester Citrate, 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane carboxylate citrate, 2-(Diethylaminoethoxy)ethyl 1-Phenyl-1-cyclopentanecarboxylate Citrate, citric acid; 2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate, 1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate, 2-(2-diethylaminoethyloxy)ethyl 1-phenylcyclopentane-1-carboxylate; 2-hydroxypropane-1,2,3-tricarboxylic acid, 2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate; 2-oxidanylpropane-1,2,3-tricarboxylic acid, 2-hydroxypropane-1,2,3-tricarboxylic acid; 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester, 5585-88-6

ID: 143

InChIKey: AKNNEGZIBPJZJG-MSOLQXFVSA-N
SMILES: CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 275196
synonyms found at PubChem are:
noscapine, Tusscapine, Terbenol, Capval, 128-62-1, Coscopin, Narcompren, Narcosine, Vadebex, Methoxyhydrastine, Narcotin, Noscapalin, Noscapin, Opianine, Opianin, NARCOTINE, Narcotussin, Longatin, Narkotin, Nectadon, Nicolane, Nipaxon, Lyobex, Opian, O-Methylnarcotoline, (-)-Narcotine, Coscotabs, alpha-Narcotine, Key-tusscapine, Noscapal, Noscapina, Noscapinum, Hederix (free base), L-alpha-Narcotine, (-)-alpha-narcotine, Noscopine, UNII-8V32U4AOQU, NSC 5366, .alpha.-Narcotine, Gnoscopine, Longactin, (S,R)-Noscapine, L-.alpha.-Narcotine, NSC-5366, 8V32U4AOQU, Noscapine hydrochloride, Noskapin, dl-Narcotine, alpha-Gnoscopine, CHEBI:73237, Noscapine dl-form, NSC5366, AKNNEGZIBPJZJG-MSOLQXFVSA-N, L-alpha-Noscapine, 8-Methoxyhydrastin, Coscopin (VAN), Noscapine HCl, (-)-alpha-Norcotine, ( -)-alpha-Narcotine, Noscapinum [INN-Latin], Noscapina [INN-Spanish], DSSTox_CID_3385, DSSTox_RID_77007, DSSTox_GSID_23385, (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one, (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one, (S)-6,7-dimethoxy-3-((R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one, HSDB 3372, Narcotine alkaloid, EINECS 204-899-2, NSC 96350, BRN 0099933, Narcotine, (+-)-, (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one, [S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-Isobenzofuranone, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)-isoquinolin-5-yl), (S-(R*,S*))-, SMR000059119, (+-)-Noscapine, (-)-.alpha.-Norcotine, (+-)-alpha-Narcotine, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (S-(R*,S*))-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-, 6035-40-1, Anarkotin, CCRIS 9304, Noscapine [USP:INN:BAN:JAN], .beta.-Narcotine, (-)-3-(2-Methyl-6,7-methylendioxy-8-methoxy-1-isochinolyl)-6,7-dimethoxyphthalid, 1-alpha-Narcotine, Noscapine (TN), (-)-noscapine, NCGC00016388-01, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (3S)-rel-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R*,S*)-, 5-(6,7-Dimethoxyphthalidyl)-5,6,7,8-tetrahydro-4-methoxy-8-methyl-1,3-dioxolo(4,5-g)isoquinoline, CAS-128-62-1, L-alpha-2-Methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinaline, Narcotine (8CI), Prestwick_959, (-)-a-Narcotine, (S,R)-Nosapine, 1-.alpha.-Narcotine, (-)-|A-Narcotine, Tocris-1697, Prestwick0_000563, Prestwick1_000563, Prestwick2_000563, Prestwick3_000563, (-)-.alpha.-Narcotine, CBMicro_048259, D0Y8AW, AC1L5H7B, SCHEMBL4559, (S,R)-Noscapine, 97%, Lopac0_000840, BSPBio_000346, 4-27-00-06838 (Beilstein Handbook Reference), MLS000069475, MLS001060855, ARONIS24067, SPBio_002565, Noscapine (JP15/USP/INN), Noscapine (JP17/USP/INN), BPBio1_000382, CHEMBL364713, DTXSID4023385, BBC/205, MolPort-000-487-311, HMS1569B08, HMS2096B08, HMS2269P05, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (3S)-, 6,7-Dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one, (S-(R*,S*))- #, Phthalide, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, Tox21_110413, BBL012344, BDBM50424716, CB3304, NSC121869, STK054401, ZINC19418974, Noscapine 1.0 mg/ml in Acetonitrile, AKOS000278036, Tox21_110413_1, API0003636, CCG-204096, CS-5115, MCULE-5334942206, NSC-121869, NCGC00023230-02, NCGC00023230-04, NCGC00023230-05, NCGC00023230-07, NCGC00023230-08, NCGC00023230-10, AC-20272, CC-33083, HY-13716, NCI60_004322, BIM-0048054.P001, H2069, C09592, D01036, A805851, C-21952, SR-01000075529-6, W-201012, 5-g)isoquinolin-5-yl)-,(s-(r*,s*))-3-dioxolo(4, 5-g]isoquinolin-5-yl)-,[s-(theta,s)]-3-dioxolo[4, BRD-K89237706-001-03-8, Noscapine, European Pharmacopoeia (EP) Reference Standard, UNII-A4C6WE7BZN component AKNNEGZIBPJZJG-MSOLQXFVSA-N, Noscapine, United States Pharmacopeia (USP) Reference Standard, WLN: T C566 DO FO KN EH & & TJ HO1 K1 J-DT56 BVO DHJ HO1 IO1, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1(3h)-isobenzofuranon, (3S)-3-[(5R)-6-methyl-4-(methyloxy)-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-bis(methyloxy)-2-benzofuran-1(3H)-one, (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-1,3-dihydro-2-benzofuran-1-one, (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R*,S*)-(+-)-, 1(3H)-Isobenzofuranone,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-, 1368-39-4, 567-86-2, 8055-18-3, 8057-19-0, Phthalide,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-

ID: 144

InChIKey: AKXCFAYOTIEFOH-XTNAHFASSA-N
SMILES: C=CCN1CC[C@]23[C@@H]4/C(=N/NC(=O)C5=CC=CC=C5)/CC[C@]2([C@H]1CC6=C3C(=C(C=C6)O)O4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9601084
synonyms found at PubChem are:
Naloxone benzoylhydrazone, Nalbzoh, 119630-94-3, 6-Desoxy-6-benzoylhydrazido-N-allyl-14-hydroxydihydronormorphinone, Benzoic acid, ((5alpha)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene)hydrazide, D05ZYZ, Lopac0_000882, [(5alpha)-4,5-Epoxy-, MLS000860072, Naloxone benzoylhydrazone, solid, CHEMBL1256836, SCHEMBL15423902, MolPort-003-958-927, MFCD05662358, AKOS024456586, CCG-204964, NCGC00092281-01, NCGC00092281-02, NCGC00092281-03, NCGC00092281-04, SMR000326930, EU-0100882, N-165, SR-01000075513, SR-01000075513-1, 3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide benzoic acid, [(5?)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene] benzoic acid hydrazide, [(5|A)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide benzoic acid, [(5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide benzoic acid

ID: 145

InChIKey: ALGDHWVALRSLBT-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC)OC)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 97332
synonyms found at PubChem are:
Quercetin pentamethyl ether, Pentamethoxyquercetin, Penta-O-methylquercitin, 1247-97-8, Pentamethylquercetin, Quercetin-3,5,7,3',4'-pentamethyl ether, 3,3',4',5,7-Pentamethoxyflavone, 3,5,7,3',4'-pentamethoxyflavone, NSC-115922, CHEMBL19032, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-, 3,5,7,3',4'-Pentamethyl ether, NSC 115922, quercetinpentamethylether, Spectrum_001718, AC1L3YAL, Spectrum2_001804, Spectrum3_001719, Spectrum4_001790, Spectrum5_000439, AC1Q6E1I, BSPBio_003338, KBioGR_002341, KBioSS_002198, MLS001048983, SPECTRUM1600075, SPBio_001787, SCHEMBL2286327, quercetin-3,5,7,3',4', 3,4',5,7-Pentamethoxyflavone, KBio2_002198, KBio2_004766, KBio2_007334, KBio3_002558, DTXSID10154467, ALGDHWVALRSLBT-UHFFFAOYSA-N, MolPort-002-508-399, HMS2268P21, ZINC1705450, BDBM50404748, CCG-38450, Flavone,3',4',5,7-pentamethoxy-, LMPK12112772, NSC115922, NSC618936, AKOS030487720, MCULE-2417652872, NSC-618936, SDCCGMLS-0066841.P001, NCGC00095759-01, NCGC00095759-02, NCGC00178132-01, CJ-28824, SMR000386999, Quercetin-3,5,7,3',4'-pentamethylether, Quercetin 3,5,7,3',4'-pentamethyl ether, FT-0716793, ST50309237, AB00637125-07, Flavone, 3,3',4',5,7-pentamethoxy- (8CI), Quercetin - 3,5,7,3',4' - pentamethylether, Quercetin 3, 5, 7, 3', 4'-pentamethylether, C-34869, SR-01000758970, SR-01000758970-2, 2-(3,4-Dimethoxy-phenyl)-3,5,7-trimethoxy-chromen-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-chromen-4-one, 4H-1-Benzopyran-4-one,4-dimethoxyphenyl)-3,5,7-trimethoxy-, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-4h-1-benzopyran-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy- (9CI)

ID: 146

InChIKey: ALKTVPFKDYZFGA-WOJBJXKFSA-N
SMILES: CC(C)CC(=O)O[C@@H]1[C@@H](C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 442128
synonyms found at PubChem are:
Dihydrosamidin, Spectrum_001514, SpecPlus_000916, AC1L9CAN, Spectrum2_000740, Spectrum3_001641, CHEBI:4583, 6005-18-1, Dimidin, Samidin, dihydro-, Spectrum4_001855, Spectrum5_000390, UNII-OD3R5Q8OVH, OD3R5Q8OVH, C09260, BSPBio_003361, KBioGR_002291, KBioSS_001994, DivK1c_007012, SPECTRUM1504161, SPBio_000700, MEGxp0_000335, CHEMBL3039391, SCHEMBL12062121, ACon0_000474, ACon1_000431, KBio1_001956, KBio2_001994, KBio2_004562, KBio2_007130, KBio3_002581, DTXSID40331744, MolPort-001-740-512, ZINC777953, CCG-40080, AKOS001483070, MCULE-3833386039, SDCCGMLS-0066815.P001, BRD-K63945320-001-03-2, (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl 3-methylbutanoate, [(9R,10R)-10-acetoxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] 3-methylbutanoate, [(9R,10R)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] 3-methylbutanoate, 2H,8H-Benzo(1,2-b:3,4-b')dipyran-2-one, 9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-, 10-acetate isovalerate, cis-(+)-, 4992-73-8, Butanoic acid, 3-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3,4-b')dipyran-9-yl ester, Butanoic acid, 3-methyl-, 10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3,4-b')dipyran-9-yl ester, (9R-cis)-, Isovaleric acid, 9-ester with 9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one acetate, cis-(+)-

ID: 147

InChIKey: ALLWOAVDORUJLA-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC=C(C=C3)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5042
synonyms found at PubChem are:
rebamipide, 90098-04-7, Mucosta, Proamipide, 111911-87-6, OPC-12759, Rebamipidum, Pramipide, Rebamipide [INN:JAN], Rebamipidum [INN-Latin], Rebamipida [INN-Spanish], OPC 12759, CCRIS 3585, Rebamipide hydrate, 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid, 2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid, Mucosta hydrate, 139344-42-6, NCGC00095161-01, Proamipide hydrate, 2-(4-chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid, (+-)-2-(4-Chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid, (+-)-1,2-Dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoic acid, (+-)-alpha-((4-Chlorobenzoyl)amino)-1,2-dihydro-2-oxo-4-quinolinepropanic acid, 4-Quinolinepropanic acid, alpha-((4-chlorobenzoyl)amino)-1,2-dihydro-2-oxo-, (+-)-, DSSTox_CID_25937, DSSTox_RID_81235, DSSTox_GSID_45937, OPC 12759 hydrate, Rebamipida, 2-(4-Chlorobenzamido)-3-[2(1H)-quinolinon-4-yl]propionic Acid, 2-(4-chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid, 2-[[(4-chlorophenyl)-oxomethyl]amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid, 4-Quinolinepropanoic acid, 1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-, (+-)-, CAS-90098-04-7, SR-05000001520, C19H15ClN2O4, 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid, N-[(4-chlorophenyl)carbonyl]-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine, 2-[(4-chlorophenyl)carbonylamino]-3-(2-oxidanylidene-1H-quinolin-4-yl)propanoic acid, Mucosta (TN), AC1L1JHF, Spectrum2_000039, Spectrum3_001959, D03BQP, Rebamipide (JP17/INN), BSPBio_003559, GTPL871, MLS006011883, SCHEMBL221527, SPECTRUM1505310, SPBio_000137, QUI103, rebamipide 111911-87-6, CHEMBL1697771, DTXSID8045937, CHEBI:93814, CTK8B3342, KBio3_002880, KS-00000SHL, AOB5606, OPC-759, ALLWOAVDORUJLA-UHFFFAOYSA-N, MolPort-000-781-642, MolPort-003-666-633, HMS1922B20, HMS2090L13, HMS3655L11, HMS3714A15, Pharmakon1600-01505310, BCP07230, HY-B0360, Tox21_111460, ANW-42341, BBL011328, CCG-39619, CR0013, MFCD11114396, NSC758955, s2032, STK577121, STL146407, (+-)-alpha-(p-Chlorobenzamido)-1,2-dihydro-2-oxo-4-quinolinepropionic acid, AKOS005501649, AKOS005721106, Tox21_111460_1, 111911-87-6 (anhyd.), AC-6841, AC-7588, AN-9620, CS-2416, DB11656, MCULE-3675104222, NSC-758955, 2-(4-chloro-benzoylamino)-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid, NCGC00095161-02, NCGC00095161-03, NCGC00095161-04, NCGC00095161-05, AN-35058, SC-15936, SMR003309276, SBI-0207054.P001, AB0073108, AB1009629, LS-142127, LS-142128, FT-0630971, FT-0655225, R0085, D01121, AB01275518-01, AB01275518_02, AB01275518_03, 911R876, A802443, A843443, I14-0511, Q-201660, SR-05000001520-1, SR-05000001520-2, SR-05000001520-3, BRD-A15909516-001-02-5, BRD-A15909516-001-03-3, 2-(4-chlorobenzoylamino)-3-(2-quinolon-4-yl)propionic acid, 2-(4-chlorobenzoylamino)-3-[2(1h)-quinolinon-4-yl] propionic acid, N-[(4-chlorophenyl)carbonyl]-3-(2-hydroxyquinolin-4-yl)alanine, 2-(4-chlorobenzoylamino)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propionic acid, 4-Quinolinepropanoic acid, |A-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (+/-)-2-(4-CHLOROBENZOYLAMINO)-3-(2(1H)-QUINOLINON-4-YL)-PROPIONIC ACID, 4-Quinolinepropanoic acid, 1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-,(+-)-, alpha-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid hydrate

ID: 148

InChIKey: AMBQHHVBBHTQBF-UOUCRYGSSA-N
SMILES: C[C@H]1[C@H](C[C@H]2[C@@H]1[C@@H](OC=C2C(=O)OC)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 87691
synonyms found at PubChem are:
Loganin, 18524-94-2, UNII-H7WJ16Q93C, Loganoside, 7-Hydroxy-6-desoxyverbenalin, H7WJ16Q93C, CHEBI:15771, EINECS 242-398-0, (-)-Loganin, Spectrum_001503, SpecPlus_000563, Spectrum2_001637, Spectrum3_001875, Spectrum4_001914, Spectrum5_000628, AC1L3E6X, Loganin, analytical standard, BSPBio_003350, KBioGR_002535, KBioSS_001983, DivK1c_006659, SCHEMBL307017, SPECTRUM1504066, SPBio_001733, MEGxp0_000723, CHEMBL1081584, ACon1_001749, KBio1_001603, KBio2_001983, KBio2_004551, KBio2_007119, KBio3_002852, AMBQHHVBBHTQBF-UOUCRYGSSA-N, MolPort-001-740-875, HY-N0512, Methyl 6-hydroxy-7-methyl-1-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5, ZINC3978792, CCG-38757, AKOS022190418, CS-5019, LMPR0102070001, MCULE-5631723150, NSC 606403, SDCCGMLS-0066747.P001, NCGC00178124-01, NCGC00178124-02, NCGC00178124-04, AJ-47574, AK-72880, CC-30021, N1327, W1729, C01433, 524L942, C-21534, Q-100220, 5A5AFFBA-93AB-4635-A071-FC87B9DC023D, (1S)-1|A-(|A-D-Glucopyranosyloxy)-1,4a|A,5,6,7,7a|A-hexahydro-6|A-hydroxy-7|A-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester, (1S,4aS,6S,7R,7aS)-1-(|A-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic Acid Methyl Ester, (1S,4aS,6S,7R,7aS)-methyl 6-hydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate, 1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester, methyl (1S,4aS,6S,7R,7aS)-1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate, methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate, methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate, methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate, methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylate, Methyl (1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha))-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta(c)pyran-4-carboxylate

ID: 149

InChIKey: AMDBBAQNWSUWGN-UHFFFAOYSA-N
SMILES: C(CO)N(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3741
synonyms found at PubChem are:
ioversol, 87771-40-2, Optiray, Optiray 320, Ioversolum [Latin], Optiray 160, Optiray 240, Optiray 350, MP-328, UNII-N3RIB7X24K, LOVERSOL, BRN 7155654, N3RIB7X24K, MP 328, 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((hydroxyacetyl)(2-hydroxyethyl)amino)-2,4,6-triiodo-, DSSTox_CID_25521, DSSTox_RID_80927, N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2-hydroxyethyl)glycolamido)-2,4,6-triiodoisophthalamide, DSSTox_GSID_45521, Optiray 300, Ioversolum, 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)-(2-hydroxyethyl)amino]-2,4,6-triiodobenzene-1,3-dicarboxamide, joversol, Ioversol [USAN:INN:BAN], Ioversol [USAN:USP:INN:BAN], NCGC00016956-01, Optiray (TN), CAS-87771-40-2, AC1L1GLW, AC1Q4PBO, Prestwick0_000878, Prestwick1_000878, Prestwick2_000878, Prestwick3_000878, D0U1ZD, Ioversol (JAN/USP/INN), SCHEMBL24711, BSPBio_000955, SPBio_002876, BPBio1_001051, CHEMBL1200614, DTXSID2045521, CHEBI:31717, CTK3E8473, AMDBBAQNWSUWGN-UHFFFAOYSA-N, C18H24I3N3O9, MolPort-005-938-391, HMS1570P17, HMS2097P17, HMS3714P17, Pharmakon1600-01503837, BCP11109, HY-B1410, Tox21_110709, AC-536, NSC760064, AKOS015896385, Tox21_110709_1, API0003020, CCG-213209, CS-7483, DB09134, NSC-760064, n,n'-bis(2,3-dihydroxypropyl)-5-[glycoloyl(2-hydroxyethyl)amino]-2,4,6-triiodoisophthalamide, NCGC00179364-01, NCGC00179364-03, AN-15742, AS-12851, BC215938, LS-29726, AB00513943, FT-0627284, P 530, D01555, AB00513943_02, 771I402, SR-01000872680, I06-1983, Q-201247, SR-01000872680-1, BRD-A65818372-001-01-2, 8771-40-2, N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide, N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2-1,3-benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-(2-hydroxyethyl)acetamido)-2,4,6-triiodoisophthalamide, N1,N3-bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)-(2-hydroxyethyl)amino]-2,4,6-triiodo-benzene-1,3-dicarboxamide

ID: 150

InChIKey: AMHZIUVRYRVYBA-UHFFFAOYSA-N
SMILES: C1CN(C(=N1)N)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2896
synonyms found at PubChem are:
cyclocreatine, 35404-50-3, 1-Carboxymethyl-2-iminoimidazolidine, UNII-6732XGX1RK, 2-(2-Iminoimidazolidin-1-yl)acetic acid, 1H-Imidazole-1-aceticacid, 2-amino-4,5-dihydro-, 6732XGX1RK, 2-(2-amino-4,5-dihydroimidazol-1-yl)acetic acid, (2-iminoimidazolidin-1-yl)acetic acid, 1H-Imidazole-1-acetic acid, 2-amino-4,5-dihydro-, Cyclocreatinine, 1-imidazolidineacetic acid, 2-imino-, Spectrum_001489, AC1L1EPT, AC1Q5WKV, Spectrum2_000925, Spectrum3_001506, Spectrum4_000329, Spectrum5_000997, D0Z8LA, BSPBio_003151, KBioGR_000677, KBioSS_001969, DivK1c_000483, SCHEMBL450343, SPECTRUM1502085, SPBio_000830, AC1Q75W5, CHEMBL179900, GTPL5491, CTK1C3187, HMS501I05, KBio1_000483, KBio2_001969, KBio2_004537, KBio2_007105, KBio3_002651, DTXSID70188889, MolPort-001-770-874, MolPort-035-395-090, NINDS_000483, HMS1921J06, 2-Imino-1-imidazolidineacetic acid, ZINC1483569, AM 285, AM-285, CCG-39671, FCH931644, NSC707961, STL371238, 2-(2-iminoimidazolidinyl)acetic acid, AKOS006222081, AKOS015912660, 1-(Carboxymethyl)-2-iminoimidazolidine, CS-W018256, LS41164, MCULE-1045168738, NSC-707961, VZ31611, 1H-Imidazole-1-acetic acid,5-dihydro-, IDI1_000483, KS-000018Z2, NCGC00094958-01, NCGC00094958-02, NCGC00094958-03, 2-(2-imino-1-imidazolidinyl)acetic acid, AS-37200, CPD000468731, KB-49177, NCI60_038283, SAM001247009, SC-25213, 2-Imino-1-imidazolidineacetic acid, 98%, KB-162438, LS-186708, LS-187408, FT-0624159, ST50998294, (2-Amino-4,5-dihydro-imidazol-1-yl)-acetic acid, C-02220, I14-47162, 2-(2-amino-4,5-dihydro-1H-imidazol-1-yl)acetic acid, 1H-Imidazole-1-acetic acid, 2-amino-4,5-dihydro- [CAS]

ID: 151

InChIKey: AMKYESDOVDKZKV-UHFFFAOYSA-N
SMILES: CC1=CC(=CC(=C1C(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 68072
synonyms found at PubChem are:
Orsellinic acid, 2,4-Dihydroxy-6-methylbenzoic acid, 480-64-8, o-Orsellinic acid, Orsellic acid, Orcinolcarboxylic acid, 4,6-Dihydroxy-o-toluic acid, UNII-11XLA0494B, Benzoic acid, 2,4-dihydroxy-6-methyl-, CHEBI:32807, 2,4-dihydroxy-6-methyl-benzoic acid, AMKYESDOVDKZKV-UHFFFAOYSA-N, 11XLA0494B, Orsellinate, 4,6-Dihydroxy-2-methylbenzoic acid, 2,4-Dihydroxy-6-methylbenzenecarboxylic acid, 2,4-Dihydroxy-6-methylbenzoic acid hydrate, Orsellinsaeure, C8-H8-O4, Spectrum_000594, ACMC-20a2aq, SpecPlus_000120, AC1Q5TGB, Spectrum2_000305, Spectrum3_001284, Spectrum4_001598, Spectrum5_000316, 6-Methyl- -resorcylic acid, BSPBio_002887, KBioGR_002216, KBioSS_001074, SPECTRUM300001, DivK1c_006216, SCHEMBL522294, SPBio_000270, AC1L28Z2, CHEMBL457583, MEGxm0_000096, CTK1D5882, KBio1_001160, KBio2_001074, KBio2_003642, KBio2_006210, KBio3_002107, KS-00000MNK, 6-Methyl-.beta.-resorcylic acid, DTXSID20197385, MolPort-001-739-322, ZINC901157, .beta.-Resorcylic acid, 6-methyl-, 6587AB, ANW-53904, BDBM50104645, CCG-38582, DT1737, LMPK13010001, MFCD16661187, 2,4-Dihydroxy-6-methyl benzoic acid, AKOS000349074, FCH1121380, MCULE-3047851108, SDCCGMLS-0066472.P001, NCGC00095565-01, NCGC00095565-02, 4CN-3035, AJ-24339, AK-77256, AN-45187, DS-17030, KB-17581, SC-91572, AX8066935, TC-142649, AM20040543, BB 0218020, FT-0693806, ST24038664, C01839, 480D648, SR-05000002400, SR-05000002400-1, 6X7

ID: 152

InChIKey: AMTSLHRSERHBCF-IBQNZTRDSA-N
SMILES: CC1(C[C@H]2[C@H]1CCC3(C(O3)CC2=C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708694
synonyms found at PubChem are:
CARYLOPHYLLENE OXIDE, KBio3_001696, Spectrum_001135, SpecPlus_000511, Spectrum2_000634, Spectrum3_000628, Spectrum4_001892, Spectrum5_000544, BSPBio_002196, KBioGR_002449, KBioSS_001615, DivK1c_006607, SPECTRUM1500832, SPBio_000628, KBio1_001551, KBio2_001615, KBio2_004183, KBio2_006751, CCG-38547, SDCCGMLS-0066695.P001, NCGC00178769-01, SR-05000002448, SR-05000002448-1

ID: 153

InChIKey: AMZACPWEJDQXGW-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)NC(=O)C(C)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 108173
synonyms found at PubChem are:
Tocainide hydrochloride, Tonocard, Tocainide HCl, Xylotocan, 35891-93-1, 71395-14-7, Tocainide hydrochloride [USP], 2-Amino-N-(2,6-dimethylphenyl)propanamide monohydrochloride, Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, monohydrochloride, DSSTox_CID_25540, DSSTox_RID_80942, DSSTox_GSID_45540, Tocainide hydrochloride (USP), 2-Amino-N-(2,6-dimethylphenyl)propanamide hydrochloride, CAS-35891-93-1, Tocainide-hydrochloride, (+)-2-Amino-N-(2,6-dimethylphenyl)propanamide monohydrochloride, Tonocard (TN), 53984-76-2, EINECS 275-361-2, AC1Q5LWF, NCGC00017005-01, Tocainide Monohydrochloride, 2-Amino-2',6'-propionoxylidide hydrochloride, SCHEMBL122779, AC1L33H5, n-(2,6-dimethylphenyl)alaninamide hydrochloride(1:1), CHEMBL1200773, DTXSID5045540, CTK1H0899, HMS1571M15, Tocainide (+-)-form hydrochloride, 41708-72-9 (Parent), Tox21_110732, Tox21_500344, Tox21_110732_1, API0008387, CCG-213604, LP00344, ACM35891931, NCGC00162129-06, NCGC00261029-01, LS-119013, D02088, Tocainide hydrochloride, >=98% (HPLC), solid, SR-01000763682, SR-01000763682-3, 2-amino-N-(2,6-dimethylphenyl)propanamide;hydrochloride, (1)-2-Amino-N-(2,6-dimethylphenyl)propionamide hydrochloride, Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, monohydrochloride, (+-)-, Tocainide hydrochloride, United States Pharmacopeia (USP) Reference Standard

ID: 154

InChIKey: ANDJPJNFVJXEKX-UHFFFAOYSA-N
SMILES: CCN1C=CN=C1CC2COC3=CC=CC=C3O2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 172975
synonyms found at PubChem are:
Imiloxan hydrochloride, Imiloxan HCl, RS 21361, 81167-16-0, Imiloxan hydrochloride [USAN], 86710-23-8, Imiloxan hydrochloride (USAN), 81167-22-8, SR-01000075942, AC1L59KH, MLS002153380, SCHEMBL124122, CHEMBL578481, CTK8G0291, ANDJPJNFVJXEKX-UHFFFAOYSA-N, MolPort-003-666-880, Tox21_500703, AKOS024458720, API0008373, CCG-222007, LP00703, NCGC00094055-01, NCGC00261388-01, SMR001230769, EU-0100703, Imiloxan hydrochloride, >98% (HPLC), solid, D04514, I 9531, SR-01000075942-1, SR-01000075942-3, 2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride, 1-Ethyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole hydrochloride, (+-)-2-((1-Ethyl-2-imidazolyl)methyl)-1,4-benzodioxane hydrochloride, (+-)-2-(1,4-Benzodioxan-2-ylmethyl)-1-ethylimidazole monohydrochloride, 2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-ethylimidazole hydrochloride, 2-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-ethyl-1H-imidazole hydrochloride, 2-[(2,3-dihydro-1,4-benzodioxin-2yl)methyl]-1-ethyl-1H-imidazole hydrochloride, 1H-Imidazole- 2-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-1-ethyl-, monohydrochloride, (+-)-, 1H-Imidazole- 2-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-1-ethyl-,monohydrochloride, (+-);

ID: 155

InChIKey: ANJTVLIZGCUXLD-DTWKUNHWSA-N
SMILES: C1[C@H]2CNC[C@@H]1C3=CC=CC(=O)N3C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10235
synonyms found at PubChem are:
CYTISINE, 485-35-8, Baptitoxine, Sophorine, (-)-Cytisine, Laburnin, Baptitoxin, Tabex, Cytiton, Cytitone, Ulexine, Baphitoxine, (1R,5S)-3,4,5,6-Tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one, Ulexin, Tsitizin, Citizin, Cystisine, Cytizin, Tabax, Cytisine (-), UNII-53S5U404NU, HSDB 3560, EINECS 207-616-0, NSC 407282, BRN 0083882, Cytisin, CHEBI:4055, CHEMBL497939, 53S5U404NU, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-Methano-8H-Pyrido[1,2-A][1,5]Diazocin-8-One, (1r,5s)-1,2,3,4,5,6-Hexahydro-8h-1,5-Methanopyrido[1,2-A][1,5]diazocin-8-One, (1R,9S)-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one, 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2a][1,5]diazocin-8-one, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one, SMR001233264, 1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-, SR-01000597582, Cytisinicline, Tsitafat, 1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-, (1R,5S)-, C5E, Prestwick_140, 6039 Sopharma, Cytisinicline [USAN], Tocris-1390, AC1L1URQ, Prestwick3_000624, D08XPW, CYTISINE (-)-, BSPBio_000588, Cytisine, >=99%, powder, 5-24-02-00535 (Beilstein Handbook Reference), MLS002153916, MLS002222174, SCHEMBL161398, BPBio1_000648, GTPL5347, (1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one, (1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one, (1S,9S)-3,11-Diazatricyclo[7.3.1.03,8]trideca-5,7-dien-4-one, 6047-01-4 (hydrochloride), CTK8B8646, 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one (cytisine), ANJTVLIZGCUXLD-DTWKUNHWSA-N, Cytisine1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one, MolPort-000-880-972, HMS2096N10, HMS2235L06, HMS3267D20, TNP00030, ZINC1599730, ANW-60953, BDBM50143282, PDSP1_000461, s2287, AKOS000276818, AKOS015833102, AB03763, CCG-208621, DB09028, EBD2185019, RL03801, RTX-012300, NCGC00016463-01, NCGC00016463-02, NCGC00016463-03, NCGC00016463-04, NCGC00017171-01, NCGC00025138-01, NCGC00025138-02, NCGC00179513-01, AJ-27955, AN-45226, AS-19539, CAS-485-35-8, LS-59087, AB0035681, KB-205376, TC-067500, TL8003259, ST24033620, Y0063, Cytisine, >=99.0% (HPLC), >=99%, W-6535, 485C358, SR-01000597582-1, SR-01000597582-5, SR-01000597582-6, SR-01000597582-7, BRD-K74186897-001-02-5, BRD-K74186897-001-04-1, BRD-K74186897-001-13-2, F9994-5373, Z2582785591, (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one, (1S,9R)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one, (1R,9S)-7,11-diazatricyclo[7.3.1.0(2),]trideca-2,4-dien-6-one, (1R,9S)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one, (1S,9S)-3,11-DIAZATRICYCLO[7.3.1.0(3,8)]TRIDECA-5,7-DIEN-4-ONE, 1267572-93-9, 1933793-08-8, 3728-36-7

ID: 156

InChIKey: ANOMHKZSQFYSBR-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 91513
synonyms found at PubChem are:
Hydroxyzine dihydrochloride, 2192-20-3, Hydroxyzine hydrochloride, 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride, Hydroxyzine 2HCl, Arcanax, Neurolax, Vistaject, Vistarex, Vistazine, Alamon, Disron, Quiess, Marax, Atranine A, Vistaril steraject, Vistaril Parenteral, Hydroxyzine (dihydrochloride), Tran-Q dihydrochloride, Ataraxoid dihydrochloride, Tranquizine dihydrochloride, EINECS 218-586-3, AI3-50162, Vistaril (TN), Atarax (TN), W-107513, CHEBI:5819, (+-)-2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride, 2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride, Dichlorhydrate de 1-p.chlorbenzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine [French], Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride, Ethanol, 2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)-, dihydrochloride, Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride, (+-)-, QYS, 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride, Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride, Hydroxyzine DiHCl, Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, hydrochloride (1:2), Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2), Prestwick_272, Atarax dihydrochloride, AC1Q3ADT, 163837-38-5, HYDROXIZINE CHLORIDE, Hydroxyzine(dihydrochloride), AC1L3M8D, Hydroxyzine Hydrochloride,(S), SCHEMBL491323, C21H27ClN2O2.2HCl, C21H29Cl3N2O2, CHEMBL3186993, DTXSID2040737, CTK8B4497, HY-B0548A, Hydroxyzine hydrochloride [USAN], ANOMHKZSQFYSBR-UHFFFAOYSA-N, MolPort-001-531-967, HMS1568K08, BCP08800, Hydroxyzine dihydrochloride, >=98%, ANW-45296, Hydroxyzine hydrochloride [USP:JAN], MFCD00058200, s4026, AKOS015846478, Hydroxyzine hydrochloride (JP17/USP), AC-8086, AN-8376, API0002955, CCG-220133, CS-2651, HS-0097, 2-(2-{4-[(4-chlorphenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethanoldihydrochlorid, KS-00001F80, NCGC00089816-02, AK-54930, BC204943, H965, LS-66602, AB0005753, AX8032687, KB-220361, ST2403814, TC-063555, FT-0658716, VU0239818-5, D00672, 192H203, SR-01000003137, SR-01000003137-2, Hydroxyzine Hydrochloride 1.0 mg/ml in Methanol (as free base), Hydroxyzine hydrochloride, European Pharmacopoeia (EP) Reference Standard, (+/-)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol hydrochloride, 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethan-1-ol dihydrochloride, 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol dihydrochloride, 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol dihydrochloride, Dichlorhydrate de 1-p.chlorbenzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine, Hydroxyzine Dihydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Hydroxyzine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Hydroxyzine dihydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, AKOS015918229, A815756, I14-7816, 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol; hydron; dichloride, 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethanol; hydron; dichloride

ID: 157

InChIKey: ANRUJJLGVODXIK-UHFFFAOYSA-N
SMILES: C1=C(NC=N1)CCNC(=O)CCN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2574
synonyms found at PubChem are:
Carcinine, 56897-53-1, N-(2-(1H-Imidazol-5-yl)ethyl)-3-aminopropanamide, beta-Alanylhistamine, UNII-WIV0W167TC, WIV0W167TC, SPBio_002343, beta-alaninylhistamine, N-beta-alanylhistamine, AC1L1DZE, Prestwick0_000422, Prestwick1_000422, Prestwick2_000422, Prestwick3_000422, Lopac-C-2321, D06ZBV, AC1Q5P6Q, n-[2-(1h-imidazol-5-yl)ethyl]-|A-alaninamide, Lopac0_000210, BSPBio_000404, KSC921E6R, MLS002153803, BPBio1_000446, CHEMBL461024, SCHEMBL2819350, SCHEMBL19051459, CHEBI:95262, CTK8C1268, DTXSID90205421, CHEBI:131429, HMS1569E06, HMS2096E06, HMS2235I06, HMS3371N06, ANW-66135, ZINC29747055, AKOS006271690, AKOS013465881, CCG-204305, SMP2_000161, NCGC00015221-01, NCGC00015221-02, NCGC00015221-03, AK-84422, SMR001233178, AX8223359, CAS-56897-53-1, RT-003724, 4CH-021715, N-[2-(1H-imidazol-4-yl)ethyl]-beta-alaninamide, 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide, Propanamide, 3-amino-N-(2-(1H-imidazol-4-yl)ethyl)-

ID: 158

InChIKey: ANVFDWBCVDQNEZ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 688670
synonyms found at PubChem are:
6,4'-DIMETHOXYFLAVONE, MLS001049126, 6-methoxy-2-(4-methoxyphenyl)chromen-4-one, 54401-47-7, SMR000386953, 4H-1-Benzopyran-4-one, 6-methoxy-2-(4-methoxyphenyl)-, 4',6-dimethoxyflavone, SR-01000400466, KBio3_001562, AC1LEMJQ, Spectrum_000874, SpecPlus_000698, AC1Q6AJO, Spectrum2_000322, Spectrum3_000591, Spectrum4_001912, Spectrum5_000624, Oprea1_516034, Oprea1_832193, BSPBio_002062, KBioGR_002531, KBioSS_001354, DivK1c_006794, SPECTRUM1500741, SPBio_000323, cid_688670, SCHEMBL4281291, CHEMBL1410006, BDBM49933, CTK1F8958, KBio1_001738, KBio2_001354, KBio2_003922, KBio2_006490, ZINC57667, ANVFDWBCVDQNEZ-UHFFFAOYSA-N, CHEBI:107663, MolPort-000-572-887, HMS2269D13, CCG-38598, AKOS000603362, 6-methoxy-2-(4-methoxyphenyl)chromone, MCULE-2190322440, SDCCGMLS-0066575.P001, NCGC00095631-01, NCGC00095631-02, NCGC00178838-01, BAS 01121754, ST50309374, 6-Methoxy-2-(4-methoxy-phenyl)-chromen-4-one, 6-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one, 6-methoxy-2-(4-methoxyphenyl)-1-benzopyran-4-one, SR-01000400466-1, SR-01000400466-3, BRD-K48629186-001-02-7, 2-(4-Methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

ID: 159

InChIKey: AOCCBINRVIKJHY-UHFFFAOYSA-N
SMILES: CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2577
synonyms found at PubChem are:
carmofur, 61422-45-5, Mifurol, HCFU, Yamaful, 1-(n-hexylcarbamoyl)-5-fluorouracil, 1-Hexylcarbamoyl-5-fluorouracil, Carmofur [INN:JAN], Carmofurum [INN-Latin], Hexylcarbamoyl fluorouracil, UNII-HA82M3RAB2, Mifurol (TN), CCRIS 2759, C11H16FN3O3, Uracil, 5-fluoro-1-hexylcarbamoyl-, BRN 0888898, HA82M3RAB2, 1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-, 5-fluoro-1-(n-hexylcarbamoyl)uracil, NCGC00095165-01, CPD000466363, 2,4-Dioxo-5-fluoro-N-hexyl-1,2,3,4-tetrahydro-1-pyrimidinecarboxamide, 2,4-Dioxo-5-fluoro-N-hexyl-3,4-dihydro-1(2H)-pyrimidinecarboxamidme, 5-fluoro-N-hexyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carboxamide, 5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide, 1-Pyrimidinecarboxamide, 1,2,3,4-tetrahydro-2,4-dioxo-5-fluoro-N-hexyl-, DSSTox_CID_25941, DSSTox_RID_81239, DSSTox_GSID_45941, 5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide, Carmofurum, 1(2H)-Pyrimidinecarboxamide, 3,4-dihydro-2,4-dioxo-5-fluoro-N-hexyl-, SMR000466363, CAS-61422-45-5, Carmofure, Yamafur, Carmofur,(S), AC1L1DZN, Spectrum2_000026, Spectrum3_001960, Carmofur (JP17/INN), D00IKH, SCHEMBL8037, BSPBio_003560, 5-24-06-00277 (Beilstein Handbook Reference), KSC613C8L, MLS000759482, MLS000759483, MLS001423992, SPECTRUM1505317, SPBio_000091, AC1Q6G43, CHEMBL460499, DTXSID2045941, CHEBI:31360, CTK5B3185, KBio3_002882, AOCCBINRVIKJHY-UHFFFAOYSA-N, MolPort-001-771-501, HMS1922D08, HMS2051G12, HMS3393G12, HMS3654F13, HMS3712P11, Pharmakon1600-01505317, BCP21373, HY-B0182, ZINC1542916, ZX-AP006448, Tox21_111464, BDBM50431275, CCG-39700, NSC758963, PC0659, s1289, SBB101867, Carmofur, >=98% (HPLC), powder, AKOS015906778, Tox21_111464_1, API0015887, Benzene,1-methyl-4-(trifluoromethyl)-, CS-2064, DB09010, NC00116, NSC-758963, VA10051, KS-0000157C, NCGC00095165-02, NCGC00095165-03, NCGC00095165-04, NCGC00095165-05, NCGC00095165-07, NCGC00177991-01, AC-12465, AN-39291, BC204681, CC-25427, R923, SAM001246692, SAM001246693, HCFU, 61422-45-5, SBI-0207040.P001, AB0018404, AB2000032, LS-134800, FT-0082424, FT-0601619, C13252, D01784, AB00698319-04, AB00698319_06, AB00698319_07, 422C455, A833212, C-16006, SR-01000763370, 5-fluoro-N-hexyl-2,4-dioxo-1-pyrimidinecarboxamide, I14-2220, SR-01000763370-3, 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide, BRD-K11630072-001-06-6, (5-fluoro-2,4-dioxo(1,3-dihydropyrimidinyl))-N-hexylcarboxamide, 5-fluoranyl-N-hexyl-2,4-bis(oxidanylidene)pyrimidine-1-carboxamide, 3,4-Dihydro-2,4-dioxo-5-fluoro-N-hexylpyrimidine-1(2H)-carboxamide

ID: 160

InChIKey: AOJIJXJCNKMEET-UVTDQMKNSA-N
SMILES: C1=CC=C(C=C1)/C(=C/C(=O)C2=CC=CC=C2O)/O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6022229
synonyms found at PubChem are:
2',beta-DIHYDROXYCHALCONE, 2'-beta-Dihydroxychalcone, AC1O0OBN, Spectrum5_000194, BSPBio_001635, SPECTRUM200123, SCHEMBL4276129, CHEMBL1451434, CCG-38355, LMPK12120395, AKOS022660919, AKOS022660926, ZINC100069442, SDCCGMLS-0066402.P001, NCGC00095470-01, NCGC00095470-02, z-1-hydroxy-1-phenyl-3-(2-hydroxyphenyl)propen-3-one, 3-Hydroxy-1-(2-hydroxyphenyl)-3-phenyl-2-propene-1-one, (Z)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one

ID: 161

InChIKey: AOOSJYIINXVNHV-UHFFFAOYSA-N
SMILES: CCCCN1CCC(CC1)COC(=O)C2=CC(=C(C3=C2OCCO3)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 121881
synonyms found at PubChem are:
SB 204070 hydrochloride, 148702-58-3, SB204070, SB-204070, SB-204,070, (1-butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate, (1-butylpiperidin-4-yl)methyl 5-amino-6-chloro-2,3-dihydro-1,4-benzodioxine-8-carboxylate, AC1L3TKM, Lopac-S-3313, D0N8EL, Lopac0_001048, GTPL256, CHEMBL68131, SCHEMBL1041174, BDBM82505, DTXSID90164069, ZINC1536586, PDSP1_001682, PDSP2_001665, AKOS027422837, CAS_121881, CCG-205125, NSC_121881, NCGC00015946-01, NCGC00015946-02, NCGC00162328-01, KB-272760, LS-187292, L000653, (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-2,3-dihydro-1,4-benzodioxine-5-carboxylate, (1-n-butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate, (1-Butyl-4-piperidyl)methyl 5-amino-4-chloro-7,10-dioxabicyclo[4.4.0]deca-2,4,11-triene-2-carboxylate

ID: 162

InChIKey: AOUYWWJPLUTFAB-NUIIJRBZSA-N
SMILES: CC(=O)O[C@@H]1[C@H]2C(C(C([C@@]3([C@@]2(O[C@]14C3CC[C@@]5(C4=CC(=O)O[C@H]5C6=COC=C6)C)O)C)CC(=O)OC)(C)C)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708633
synonyms found at PubChem are:
XYLOCARPUS A, KBio3_001709, Spectrum_000519, SpecPlus_000281, Spectrum2_000391, Spectrum3_000705, Spectrum4_001364, Spectrum5_000008, BSPBio_002489, KBioGR_001628, KBioSS_000999, SPECTRUM100424, DivK1c_006377, SPBio_000601, CHEMBL3039346, SCHEMBL17792910, KBio1_001321, KBio2_000999, KBio2_003567, KBio2_006135, CCG-38662, SDCCGMLS-0066326.P001, NCGC00178632-01, SR-05000002760, SR-05000002760-1

ID: 163

InChIKey: APMORJJNVZMVQK-UHFFFAOYSA-N
SMILES: CC1CC(CCC1C(=O)OC(C)(C)C)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 546164
synonyms found at PubChem are:
Trimedlure, 12002-53-8, Trimedlure (Mixture of Isomers), APMORJJNVZMVQK-UHFFFAOYSA-N, Cyclohexanecarboxylic acid, 4(or 5)-chloro-2-methyl-, 1,1-dimethylethyl ester, 7771-58-6, Capilure, Pherocon MFF, EINECS 234-416-0, ENT 31560, AI3-31560, AC1LC1I1, SCHEMBL434080, t-Butyl 4(or 5)-chloro-2-methylcyclohexanecarboxylate, 2-Methyl-4-chlorocyclohexanecarboxylicacidtert-butylester, 1,1-Dimethylethyl 4(or 5)-chloro-2-methylcyclohexanecarboxylate, 4-(or 5)Chloro-2-methylcyclohexanecarboxylic acid, 1,1-dimethyl ester, AKOS030230635, NCGC00094562-01, NCGC00094562-02, CC-35374, LS-56634, FT-0699819, t-butyl-2-methyl-4-chlorocyclohexanecarboxylate, C-23900, tert-Butyl 4-chloro-2-methylcyclohexanecarboxylate, A1-03527, tert-Butyl 4-chloro-2-methylcyclohexanecarboxylate #, tert-butyl 4-chloro-2-methylcyclohexane-1-carboxylate, Cyclohexanecarboxylic acid, 4-(or 5)-chloro-2-methyl-, tert-butyl ester, Cyclohexanecarboxylic acid, 4-chloro-2-methyl-, 2,2-dimethylethyl ester

ID: 164

InChIKey: APNJDIVXMGGHDX-MHKPZZPRSA-N
SMILES: C[C@@]12CCC3[C@]4(C=C[C@@H](C(C4CC(=O)[C@]3([C@@]15[C@H](O5)C(=O)O[C@H]2C6=COC=C6)C)(C)C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708781
synonyms found at PubChem are:
KBio3_001042, Spectrum_000749, SpecPlus_000804, Spectrum2_000374, Spectrum3_000141, Spectrum4_001419, Spectrum5_000218, BSPBio_001842, KBioGR_001838, KBioSS_001229, DivK1c_006900, SPBio_000527, SCHEMBL10019473, KBio1_001844, KBio2_001229, KBio2_003797, KBio2_006365, CCG-38647, SDCCGMLS-0066440.P001, NCGC00178964-01

ID: 165

InChIKey: AQCHWTWZEMGIFD-UHFFFAOYSA-N
SMILES: CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4170
synonyms found at PubChem are:
metolazone, 17560-51-9, Zaroxolyn, Diulo, Mykrox, Microx, Metalozone, Metenix, Oldren, Metolazona, Metolazonum, 7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide, Metolazonum [INN-Latin], Metolazona [INN-Spanish], Metalazone, Xuret, 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, Metolazone (Zaroxolyn), SR 720-22, SR-720-22, Zaroxolyn (TN), HSDB 3367, 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone, Metolazone [USAN:BAN:INN:JAN], 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide, EINECS 241-539-3, UNII-NM7V2Y3G0U, BRN 0965506, NM7V2Y3G0U, Metolazone (JAN/USP/INN), 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, UNII-NN9U607695, CHEBI:64354, AQCHWTWZEMGIFD-UHFFFAOYSA-N, 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-, 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide, NN9U607695, NCGC00093985-07, 6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-, 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide, DSSTox_CID_25167, DSSTox_RID_80717, DSSTox_GSID_45167, Q-201399, SMR001230730, SR-05000001765, metozalone, Metolazon, Prestwick_333, CAS-17560-51-9, metolazone (product), Mykrox (TN), Metolazone(Zaroxolyn), Metolazone, (+)-, Metolazone, (-)-, Metolazone [USAN:USP:INN:BAN:JAN], SR72022, Metolazone(Zaroxolyn)/, Spectrum_000456, AC1L1HKJ, Prestwick0_000112, Prestwick1_000112, Prestwick2_000112, Prestwick3_000112, Spectrum2_001741, Spectrum4_000229, Spectrum5_001237, CHEMBL878, D01WLC, (non-labelled)Metolazone-d7, SCHEMBL40558, BSPBio_000124, BSPBio_002422, KBioGR_000897, KBioSS_000936, 5-25-09-00212 (Beilstein Handbook Reference), MLS002153316, MLS002154200, DivK1c_000275, SPECTRUM2300325, SPBio_001842, SPBio_002063, BPBio1_000138, GTPL4838, DTXSID6045167, Mykrox;Zaroxolyn;Diulo;Zaroxolyn, BDBM25899, CTK8B4741, HMS500N17, KBio1_000275, KBio2_000936, KBio2_003504, KBio2_006072, KS-00000ZJQ, MolPort-003-666-780, NINDS_000275, BCPP000166, HMS1568G06, HMS1922L16, HMS2093P14, HMS2095G06, HMS2230J15, HMS3261J22, HMS3373C11, HMS3655M09, HMS3712G06, Pharmakon1600-02300325, BCP21574, EBD54305, HY-B0209, Tox21_110186, Tox21_113526, Tox21_500610, ABP000634, ANW-46001, CCG-39450, MFCD00069304, NSC759581, s1610, Mykrox, Zaroxolyn, Diulo, Metolazone, AKOS015897109, Metolazone, >=98% (HPLC), solid, Tox21_110186_1, API0003352, BCP9000920, CS-2150, DB00524, KS-5139, LP00610, NSC-759581, IDI1_000275, NCGC00093985-01, NCGC00093985-02, NCGC00093985-03, NCGC00093985-04, NCGC00093985-05, NCGC00093985-06, NCGC00093985-08, NCGC00093985-10, NCGC00093985-11, NCGC00261295-01, 4CA-0814, AN-11710, AS-13016, CC-30932, H024, SBI-0051460.P002, AB0012835, AB2000160, AX8140044, KB-249688, LS-140226, TC-134746, AB00052055, FT-0628932, ST24029920, D00431, 7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4, AB00052055-08, AB00052055_09, AB00052055_10, 560M519, C-21013, SR-05000001765-1, SR-05000001765-4, SR-05000001765-7, BRD-A61793559-001-05-7, BRD-A61793559-001-08-1, Metolazone, European Pharmacopoeia (EP) Reference Standard, Metolazone, United States Pharmacopeia (USP) Reference Standard, 7-chloro-2-methyl-3-(o-tolyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide, 7-Chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydro-6-quinazolinesulfonamide #, 7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquizoline-6-sulfomide, Metolazone for system suitability, European Pharmacopoeia (EP) Reference Standard, 56436-31-8, 56436-32-9, 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, (+)-, 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, (-)-

ID: 166

InChIKey: AQIXAKUUQRKLND-UHFFFAOYSA-N
SMILES: CC1=C(N=CN1)CSCCNC(=NC)NC#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2756
synonyms found at PubChem are:
cimetidine, 51481-61-9, Tagamet, Tametin, Eureceptor, Cimetag, Acinil, Tratul, Dyspamet, Ulcedine, Cimetum, Ulcedin, Cimal, Acibilin, Cimetidina, Gastromet, Edalene, Ulcimet, Ulcomet, Ulhys, Tagamet Hb, Cimetidine Hcl, Tagamet Hb 200, Cimetidinum, Ulcomedina, Metracin, Ulcerfen, Valmagen, Altramet, Gastrobitan, Ulcestop, Ulcofalk, Evicer, Peptol, Sigmetadine, Histodil, Magicul, Venopex, SKF 92334, SKF-92334, Cimetidinum [INN-Latin], Cimetidina [INN-Spanish], Biomet400, Brumetidina, Cimetadine, Ci metum, DRG-0150, Tagamet (TN), 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, 2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine, Cimetidine, A Type, UNII-80061L1WGD, N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine, CCRIS 3247, CHEBI:3699, CIMETIDINE A, CIMETIDINE A/AB, HSDB 3917, Cimetidine [USAN:INN:BAN:JAN], FPF 1002, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine, CHEMBL30, EINECS 257-232-2, SK&F-92334, Brumetadina, 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, MLS000069791, C10H16N6S, AQIXAKUUQRKLND-UHFFFAOYSA-N, 80061L1WGD, 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine, Guanidine, N-cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, NCGC00015240-06, SMR000038895, DSSTox_CID_329, 2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine, C 4522, 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, DSSTox_RID_75517, Guanidine, N-cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio) ethyl)-, Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, N-Cyano-N'-Methyl-N''-(2-(((5-Methyl-1H-Imidazol-4-YL)Methyl)Thio)Ethyl) Guanidine, DSSTox_GSID_20329, 1-Cyano-2-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine, (E)-2-cyano-1-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine, 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, 2-cyano-1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine, 3-cyano-2-methyl-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine, Guanidine, N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Guanidine, N''-cyano-N-methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)-ethyl)guanidine, N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N''-Cyano-N-methyl-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine, N-Cyano-N'-methyl-[2-[[[5-methyl-1H-imidazol-4-yl]methyl]thio]ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1 H-imidazol-4-yl) methyl)thio)ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine, N-cyano-N'-methyl-N''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, 76181-71-0, Guanidine, N-cyano-N'-Methyl-N''-[2-[[(5-Methyl-1H-iMidazol-4-yl)Methyl]thio]ethyl]-, (Z)-, Equaline acid reducer, Topcare heartburn relief, SR-01000075260, SR-05000001434, cemitidine, metidine, ulcerex, Neutronorm, Azucimet, Cimagen, Cimeldine, Cimetidin, Cimetimax, Galenamet, Neutromed, Peptimax, Phimetin, Ulcometin, Ulcostad, Acitak, Cedine, Ultek, Cime, Zita, 1-cyano-2-methyl-3-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)guanidine, 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine, Cimetidine,(S), N-CYANO-N'-METHYL-N''-(2-[[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL)GUANIDINE, DuraH2, Prestwick_65, {(1E)-1-(methylamino)-4-[(4-methylimidazol-5-yl)methylthio]-2-azabut-1-enyl}am inocarbonitrile, Tagamet HB (TN), Cimetidine (Tagamet), Cimetidine [USAN:USP:INN:BAN:JAN], 7CIMETIDINE, Cimetidine (Type AB), Spectrum_000495, Tocris-0902, Opera_ID_314, CIMETIDINE A TYPE, Prestwick3_000026, Spectrum2_000782, Spectrum3_001389, Spectrum4_000812, Spectrum5_001541, Lopac-C-4522, Tagamet HB200 (TN), D02DPA, UPCMLD-DP029, AC1L1EE8, AC1Q3XK6, SCHEMBL1093, SCHEMBL1094, SKF-92334; Tagamet, Lopac0_000293, BSPBio_000091, BSPBio_002978, KBioGR_001323, KBioSS_000975, US9138393, Cimetidine, US9144538, Cimetidine, MLS001148596, MLS002153265, MLS002154178, DivK1c_000166, SPECTRUM1500684, SPBio_000884, BPBio1_000101, Cimetidine (JP15/USP/INN), Cimetidine (JP17/USP/INN), GTPL1231, DTXSID4020329, SCHEMBL11282982, UPCMLD-DP029:001, BDBM22889, HMS500I08, KBio1_000166, KBio2_000975, KBio2_003543, KBio2_006111, KBio3_002198, MolPort-001-838-193, MolPort-002-542-886, MolPort-003-895-998, MolPort-016-638-396, MolPort-020-109-101, MolPort-020-313-426, NINDS_000166, BDBM181119, HMS1921C14, HMS2089O03, HMS2092I14, HMS2095E13, HMS2232F16, HMS3259M15, HMS3260L08, HMS3267A03, HMS3369L10, HMS3651E21, HMS3712E13, Pharmakon1600-01500684, Cimetidine 1.0 mg/ml in Methanol, EX-A1088, Tox21_110106, Tox21_201160, Tox21_500293, ANW-46065, BDBM50103595, BDBM50403559, CCG-40160, MFCD00133296, NSC335308, NSC757428, s1845, SBB057794, STK528249, ZINC18115268, AKOS005460997, AKOS015900557, AKOS015951369, AKOS016003398, AKOS016340377, AKOS026749950, AKOS032949548, Tox21_110106_1, AB03708, AC-8100, AN-8331, CCG-204388, CCG-220026, CCG-221597, CS-2325, DB00501, KS-5087, LP00293, LS-7278, MCULE-2885245608, NC00501, NSC 335308, NSC-335308, NSC-757428, IDI1_000166, NCGC00015240-01, NCGC00015240-02, NCGC00015240-03, NCGC00015240-04, NCGC00015240-05, NCGC00015240-07, NCGC00024859-01, NCGC00024859-02, NCGC00024859-03, NCGC00024859-04, NCGC00024859-05, NCGC00091439-01, NCGC00091439-02, NCGC00091439-03, NCGC00091439-04, NCGC00091439-05, NCGC00091439-07, NCGC00185989-01, NCGC00188961-01, NCGC00258712-01, NCGC00260978-01, AJ-70318, CPD001370748, H505, HY-14289, KB-79578, LS-73445, LS-73446, NCI60_002936, SAM002554892, SC-15209, SBI-0050281.P004, AB0013083, AB1009523, TC-134810, TL8003410, EU-0100293, FT-0602955, ST24048532, ST50411770, C06952, D00295, J10340, M-1577, AB00052157-03, AB00052157_04, AB00052157_05, 481C619, A828616, L000186, L003827, L013434, SR-05000001750, I14-0371, Q-200855, Q-200856, SR-01000075260-1, SR-01000075260-3, SR-05000001434-1, SR-05000001434-2, SR-05000001750-1, BRD-K18618618-001-01-6, BRD-K34157611-001-04-6, BRD-K34157611-001-07-9, Z1259192068, Cimetidine, European Pharmacopoeia (EP) Reference Standard, 4H -Dithieno[3,2-b :2',3'-d ]pyrrole, 4-(1-octylnonyl)-, Cimetidine, United States Pharmacopeia (USP) Reference Standard, 1-Ethyl-2,3-dimethylimidazolium tosylate, 98% [EDiMIM] [TOS], Tagamet, SKF-92334, Tratul, Tametin, Dyspamet, Acinil, Cimetidine, 1-Cyan-2-methyl-3-(2-{[(5-methylimidazol-4-yl)methyl]thio}ethyl)guanidin, Cimetidine, Pharmaceutical Secondary Standard; Certified Reference Material, N"-cyano-N-methyl-N'-[2-(5-methylimidazol-4-ylmethylthio)ethyl]-guanidine, N"-cyano-N-methyl-N'-[2-(5-methylimidazol-4-ylmethylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine, (E)-2-CYANO-1-METHYL-3-(2-((5-METHYL-1H-IMIDAZOL-4-YL)METHYLTHIO)ETHYL)GUANIDINE, (E)-2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, (Z)-1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, (Z)-2-CYANO-1-METHYL-3-(2-((5-METHYL-1H-IMIDAZOL-4-YL)METHYLTHIO)ETHYL)GUANIDINE, 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)-benzenesulfonamide(Cimetidine), 2-Methyl-8-phenethyl-imidazo[1,2-a]pyridine-3-carboxylic acid methyl ester(cimetidine), 2-methylamino-2-[2-(4-methyl-1H-5-imidazolylmethylsulfanyl)ethylamino]-(E)-1-imino cyanide, 3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, 4-(((2-(((cyanoamino)(methylamino)methylene)amino)ethyl)thio)methyl)-5-methyl-1H-imidazole, Cimetidine for peak identification, European Pharmacopoeia (EP) Reference Standard, Cimetidine for system suitability, European Pharmacopoeia (EP) Reference Standard, Guanidine, N-cyano-N'-methyl-N''-[2-[[5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, N''-cyano-N-methyl-N'-(2-((5-methyl-1h-imidazol-4-yl)-methylthio)ethyl)guanidine, N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, N-cyano-N'-methyl-N"- [2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl) methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)- methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methyl-thio)ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl) guanidine, N-cyano-N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)-ethyl]guanidine, N-cyano-N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]-guanidine, N-cyano-N'-methyl-N"-[2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine #, N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methylimidazol-4-yl]methyl]thio]ethyl)guanidine, N-cyano-N'-methyl-N-"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine, N-methyl-N'-{2-[(5-methylimidazol-4-yl)-methylthio]-ethyl}-N"-cyanoguanidine, N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]-1-cyanoiminomethanediamine, N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]imino(-N-cyano)methanediaminem, N-tert-Butyl-N''''''''-[4-(1H-imidazol-4-yl)-phenyl]-formamidine(cimetidine), (Cimetidine) N-Methyl-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine,cyanide, (cimetidine) N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanoiminomethanediamine, (Cimetidine)N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanomethyliminomethanediamine, 2-methylamino-2-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylamino]-(Z)-1-imino cyanide(cimetidine), 270574-63-5, 2984-61-4, 943920-67-0, Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, [C(Z)]-, N''''''''''''''''''''''''''''''''-cyano-N-methyl-N''''''''''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N''''''''''''''''-cyano-N-methyl-N''''''''-({[(5-methyl-1H-imidazol-4-yl)methyl]thio}methyl)guanidine(cimetidine), N''''''''''''''''-cyano-N-methyl-N''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]-lambda~4~-sulfanyl}ethyl)guanidine, N''''''''''''''''-cyano-N-methyl-N''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N''''''''''''''''-cyano-N-methyl-N''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine (Cimetidine), N''''''''''''''''-cyano-N-methyl-N''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine(cimetidine), N-Cyano-N''''''''-methyl-N''''''''''''''''-(2-(((5-methyl-1H-imidazol-4-yl) methyl)thio)ethyl)guanidine(Cimetidine), N-cyanomethyl-N''''''''-methyl-N''''''''''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine ( Cimetidine), N-Methyl-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-cyanoguanidine(cimetidine), N-Methyl-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-N''''''''''''''''-Cyano-guanidine, N-Methyl-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-N''''''''''''''''-cyano-guanidine(Cimetidine), N-methyl-N''''''''-cyano-N''''''''''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine, N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanoiminomethanediamine (cimetidine)

ID: 167

InChIKey: AQLAXCGHPBMFIJ-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)OCC(C(C)C)N.I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957611
synonyms found at PubChem are:
R(-)-Me5 hydriodide, R(-)-Me5, 1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydriodide, EU-0100772, MLS002153485, R(-)-Me5 hydriodide, solid, CHEMBL1480136, CTK8G2721, Tox21_500772, CCG-222076, LP00772, NCGC00094111-01, NCGC00261457-01, SMR001230832, M 0814, SR-01000075975, SR-01000075975-1, 1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydroiodide, 1173019-55-0

ID: 168

InChIKey: AQTITSBNGSVQNZ-UHFFFAOYSA-N
SMILES: CC1CC2=CC3=C(C=C2C(=NN1)C4=CC=C(C=C4)N)OCO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3539
synonyms found at PubChem are:
GYKI 52895, 114460-08-1, 4-(8-Methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline, 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine, CHEBI:79613, AQTITSBNGSVQNZ-UHFFFAOYSA-N, GYKI-52895, 4-(8,9-Dihydro-8-methyl-7H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)benzenamine, Benzenamine, 4-(8,9-dihydro-8-methyl-7H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)-, 4-(8,9-Dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine, C15094, AC1L1G5W, GYKI 52895, solid, Lopac0_000562, SCHEMBL6995439, CHEMBL1256984, CTK6C4832, 2387AA, ANW-70784, 1-(4-Aminophenyl)-4-methyl-7,8-, AKOS016007859, API0008307, CCG-204652, NCGC00015464-02, NCGC00015464-03, NCGC00093947-01, NCGC00093947-02, LS-28280, AX8239223, KB-238707, TC-159529, EU-0100562, G-120, SR-01000075406, SR-01000075406-1, methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine hydrochloride, 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3benzodiazepine, 4-(8-methyl-8,9-dihydro-7h-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline

ID: 169

InChIKey: AQXXZDYPVDOQEE-MXDQRGINSA-N
SMILES: CN1CCCN=C1/C=C/C2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281033
synonyms found at PubChem are:
pyrantel pamoate, 22204-24-6, Pyrantel embonate, Antiminth, Combantrin, Embovin, Pyrantel (pamoate), CP-10,423-16, UNII-81BK194Z5M, EINECS 244-837-1, NSC 355080, CHEBI:8655, 81BK194Z5M, NSC355080, (E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1), (E)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate), 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)pyrimidine (1:1), Sentry hc worm X, 2-Naphthoic acid, 4,4'-methylenebis(3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1), 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1), Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)-, compd. with 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) (1:1), Sentry hc worm X DS, Vetscription sure shot 2X, Cobantril, Helmintox, Nemocid, Piranver, Helmex, Pyrantel pamoate [USAN:JAN], Early Bird, Antiminth (TN), Pyrantel pamoate [USAN:USP:JAN], 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine, C23H16O6.C11H14N2S, AC1NQXXE, Spectrum5_001373, Pyrantel pamoate, BioXtra, (3-hydroxy-2-naphthoate), SCHEMBL41025, SPECTRUM1500517, Pyrantel pamoate (JP17/USP), SCHEMBL7793068, CHEMBL1599768, C34H30N2O6S, HMS500M16, Pyrantel Pamoate Sigmaultra,(S), MolPort-003-666-276, HMS1920N06, HMS2090J21, HMS2092E07, Pharmakon1600-01500517, CCG-39242, NSC757303, STL481883, AKOS015908224, CS-3869, NSC-355080, NSC-757303, IDI1_000254, NCGC00094552-01, NCGC00094552-02, NCGC00094552-03, 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy), compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)pyrimidine (1:1), AC-24204, AK198640, AS-12185, CC-34082, HY-12640, LS-95387, SBI-0051499.P003, AB2000606, CP 10423-16, CP-10423-16, C07389, D00486, 204P246, A816013, SR-05000001708, SR-05000001708-1, Pyrantel pamoate, VETRANAL(TM), analytical standard, (E)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6, Pyrantel embonate, European Pharmacopoeia (EP) Reference Standard, Pyrantel pamoate, United States Pharmacopeia (USP) Reference Standard, (E)-1,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine 4,4'-methylenebis[3-hydroxy-2-naphthoate] (1:1), 1,4,5,6-Tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate], 1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4 inverted exclamation marka-methylenebis(3-hydroxy-2-naphthoic acid), 1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid), 122157-48-6, 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy-, compd. with 1,4,5,6-tetrahydro-1-methyl-2-((1E)-2-(2-thienyl)ethenyl)pyrimidine (1:1), 2-Naphthalenecarboxylic acid,4'-methylenebis[3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine (1:1), 2-Naphthoic acid,4'-methylenebis[3-hydroxy-, compd. with (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine (1:1), 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylic acid) - 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine (1:1), 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid compound with 1,4,5,6-Tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine, 4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid; 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine, 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 1-methyl-2-[(E)-2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine, 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine, 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid; 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine, 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid; 1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine, Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[2-(-2-thienyl)ethenyl-, (E)-, with 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid (1:1)

ID: 170

InChIKey: ARSRJFRKVXALTF-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1O)O)O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281701
synonyms found at PubChem are:
Tricetin, 5,7,3',4',5'-Pentahydroxyflavone, 520-31-0, Hieracin, 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one, UNII-5627PY99ZO, 5,7,3,4,5-pentahydroxyflavone, CHEBI:507499, C10192, 5627PY99ZO, 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one, AR-683/41530196, MYF, Myricetin impurity 1, AC1NQYXD, Spectrum_001591, SpecPlus_000826, Spectrum2_000741, Spectrum3_001617, Spectrum4_001678, Spectrum5_000615, BSPBio_003253, KBioGR_002235, KBioSS_002071, DivK1c_006922, SCHEMBL158384, SPECTRUM1504115, SPBio_000722, CHEMBL247484, BDBM26656, CTK7J8581, KBio1_001866, KBio2_002071, KBio2_004639, KBio2_007207, KBio3_002473, DTXSID60199964, 2o65, ARSRJFRKVXALTF-UHFFFAOYSA-N, MolPort-003-665-808, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-, ACM520310, CCG-40135, LMPK12110847, ZINC13520048, 3',4',5,5',7-pentahydroxyflavone, AKOS024287743, DB08230, MCULE-5962995471, SDCCGMLS-0066804.P001, NCGC00095682-01, NCGC00095682-02, NCGC00178184-01, BP-10199, ST50309243, SR-05000002560, SR-05000002560-1, BRD-K22585547-001-03-3, 5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one, 5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one, 9CI

ID: 171

InChIKey: ARUMZUNJBHSOQQ-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C(=O)NCCN)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5702251
synonyms found at PubChem are:
N-(2-Aminoethyl)-4-chlorobenzamide hydrochloride, 94319-79-6, Ro 16-6491, Ro 16-6491 hydrochloride, SR-01000075644, AC1NWAX1, AC1Q3DDL, EU-0101103, SCHEMBL663099, CHEMBL1256177, CTK8G2978, DTXSID20420645, ARUMZUNJBHSOQQ-UHFFFAOYSA-N, MolPort-003-666-494, Ro 16-6491 hydrochloride, solid, CCG-39506, MFCD00078595, AKOS027383242, MCULE-5299854133, NE17868, NCGC00094375-01, NCGC00094375-02, NCGC00178277-01, DB-057488, KB-309974, FT-0629101, R-106, EN300-29221, (RO-16-6491), N-(2-aminoethyl)-p-chlorobenzamide hydrochloride, A844916, N-(2-amino-ethyl)-4-chlorobenzamide hydrochloride, SR-01000075644-2, SR-01000075644-3, N-(2-azanylethyl)-4-chloranyl-benzamide hydrochloride, Z285139152, BENZAMIDE,N-(2-AMINOETHYL)-4-CHLORO-, HYDROCHLORIDE (1:1), AKOS024378003, ST51021593, N-(2-aminoethyl)(4-chlorophenyl)carboxamide, chloride

ID: 172

InChIKey: ASHYBFCDTYPECZ-UHFFFAOYSA-N
SMILES: C1CCN(C1)CC#CCN2CCCC2.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71074
synonyms found at PubChem are:
Tremorine dihydrochloride, Tremorine dichlorohydrate, EINECS 206-097-8, 300-68-5, 1,1'-(2-Butynylene)dipyrrolidine dihydrochloride, 1,4-Dipyrrolidino-2-butyne dihydrochloride, 1,1'-But-2-ynylenedipyrrolidinium dichloride, Pyrrolidine, 1,1'-(2-butynylene)di-, dihydrochloride, Tremorine HCl, Prestwick_479, AC1L2FHP, AC1Q3A1V, SCHEMBL3757253, DTXSID10184082, HMS1569C03, pyrrolidine, 1,1'-(2-butyne-1,4-diyl)bis-, dihydrochloride(9ci), CCG-220331, MCULE-1964662129, LS-137294, ST50448544, SR-01000872650, SR-01000872650-1, (4-pyrrolidinylbut-2-ynyl)pyrrolidine, chloride, chloride, 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidine dihydrochloride, 1-(4-pyrrolidin-1-ylbut-2-ynyl)pyrrolidine,dihydrochloride, 1-[4-(1-pyrrolidinyl)-2-butynyl]pyrrolidine dihydrochloride, Pyrrolidine, 1,1'-(2-butyne-1,4-diyl)bis-, dihydrochloride, Pyrrolidine, 1,1'-(2-butyne-1,4-diyl)bis-, dihydrochloride (9CI), 1,1 inverted exclamation marka-(2-Butynylene)dipyrrolidine dihydrochloride

ID: 173

InChIKey: ASNFTDCKZKHJSW-REOHCLBHSA-N
SMILES: C([C@@H](C(=O)O)N)N1C(=O)NC(=O)O1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 40539
synonyms found at PubChem are:
QUISQUALIC ACID, Quisqualate, 52809-07-1, L-Quisqualic acid, (+)-Quisqualic acid, [3H]quisqualate, UNII-8OC22C1B99, C5H7N3O5, CHEBI:8734, CHEMBL279956, 8OC22C1B99, (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid, 2jbk, 1,2,4-Oxadiazolidine-2-propanoic acid, alpha-amino-3,5-dioxo-, (S)-, 2or4, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, AC1ODZB5, (S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, QUS, SR-01000075471, CHEMBL168279, Quisqualate, L, ()-Quisqualic Acid, Tocris-0188, 1mm6, 1mm7, 1p1o, Quisqualic acid, powder, D06DUE, D0W6JO, beta-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, AC1L23YS, AC1Q6GK0, Lopac0_001039, MLS001074741, SCHEMBL136819, GTPL1370, GTPL1372, SCHEMBL13319908, BDBM17660, CTK4J6551, ASNFTDCKZKHJSW-REOHCLBHSA-N, MolPort-003-939-212, HMS2233G05, HMS3263O19, ZINC897456, BCP13297, Tox21_501039, BDBM50164445, BN0434, MFCD00069337, PDSP1_000814, PDSP2_000801, AKOS024456826, CCG-205116, DB02999, FCH4012693, LP01039, ACM52809071, NCGC00024489-01, NCGC00024489-02, NCGC00024489-03, NCGC00024489-04, NCGC00024489-05, NCGC00261724-01, KB-60323, QC-11635, SMR000471890, LS-175398, EU-0101039, FT-0604435, ST50825297, V0329, C08296, Q 2128, 809Q071, C-52964, SR-01000597681, SR-01000075471-1, SR-01000075471-5, SR-01000597681-1, (L)-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid, 1,2,4-Oxadiazolidine-2-propanoicacid, a-amino-3,5-dioxo-, (aS)-, 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid, L(+)-alpha-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid, (2S)-2-amino-3-(3,5-dioxo(1,2,4-oxadiazolidin-2-yl))propanoic acid, 2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid(Quisqualic acid), 3fee, (2S)-2-azaniumyl-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoate

ID: 174

InChIKey: ASNSHZBVZYSNTB-UHFFFAOYSA-N
SMILES: CCCCCC(C)N.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107130
synonyms found at PubChem are:
3459-07-2, Hexylamine, sulfate, EINECS 251-512-8, ACMC-20aprq, (1)-(1-Methylhexyl)ammonium sulphate, AC1Q6XEA, heptan-2-amine,sulfuric acid, SPECTRUM1500601, heptan-2-amine; sulfuric acid, (+/-)-2-Heptylamine sulfate, AC1L31I2, CHEMBL1368028, SCHEMBL15475282, (+/-)-2-Aminoheptane sulphate, (1-Methylhexyl)ammonium sulphate, CTK3I9432, HMS500N09, WLN: ZY5&1 &S-O4, HMS1921I13, HMS2092A22, Pharmakon1600-01500601, NSC27117, EINECS 222-742-6, CCG-39597, NSC-27117, NSC148303, NSC757374, TUAMINOHEPTANE SULFATE (2:1), NSC-148303, NSC-757374, NCGC00094806-02, 33423-91-5, TC-173069, SR-05000001734, SR-05000001734-1

ID: 175

InChIKey: ASTPOGDWGNJVEW-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4303263
synonyms found at PubChem are:
IRETOL, 2-methoxybenzene-1,3,5-triol, 487-71-8, 2-Methoxy-phloroglucinol, 2-METHOXY-BENZENE-1,3,5-TRIOL, 1,3,5-trihydroxy-2-methoxybenzene, KBio1_001103, Spectrum_000615, SpecPlus_000063, Spectrum2_000202, Spectrum3_000189, Spectrum4_001508, Spectrum5_000275, BSPBio_001717, KBioGR_002175, KBioSS_001095, SPECTRUM200759, DivK1c_006159, SPBio_000183, AC1N7J10, SCHEMBL3190103, CHEMBL1606248, CTK4J0988, KBio2_001095, KBio2_003663, KBio2_006231, KBio3_001217, DTXSID90401729, ZINC2566737, CCG-38408, FCH841647, AKOS006271395, ACN-053295, AN-6516, CHM0009010, SDCCGMLS-0066399.P001, NCGC00095488-01, NCGC00095488-02, AC-12884, AJ-41318, SR-05000002390, SR-05000002390-1

ID: 176

InChIKey: ASXGJMSKWNBENU-UHFFFAOYSA-N
SMILES: CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1220
synonyms found at PubChem are:
8-OH-Dpat, 78950-78-4, 8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN, 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol, CHEMBL56, Ro-31-8220 in solution, [3H]8-OH-DPAT, CHEBI:73364, 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT, (+/-)-8-HYDROXY-2-DIPROPYL-AMINOTETRALIN, [3H]-8-OH-DPAT, 8-Hydroxy-DPAT, (+/-)-8-Hydroxy-DPAT hydrobromide, (+-)-8-OH-DPAT, S(-)-8-OH-DPAT HBr, dl-8-Hydroxy-2-(dipropylamino)tetralin, S(-)-8-Hydroxy-DPAT hydrobromide, GTPL7, AC1L1AZN, AC1Q2XPY, Biomol-NT_000095, D0O3GF, GTPL31, AC1Q7AL7, cid_1220, Lopac0_000576, SCHEMBL496783, BPBio1_001354, 8-OH-DPAT,(+), 8-OH-DPAT,(-), BDBM21393, CTK5E6257, ASXGJMSKWNBENU-UHFFFAOYSA-N, MolPort-044-830-676, 8-OH-DPAT (8-Hydroxy-DPAT), 8-hydroxy-n,n-dipropylaminotetralin, BCP25681, MFCD00153811, PDSP1_000777, PDSP2_000765, AKOS030627213, CCG-204665, NCGC00015493-04, NCGC00015493-05, NCGC00015493-06, NCGC00024635-02, NCGC00024635-03, NCGC00024986-02, LS-94994, (+)-8-Hydroxy-2-(dipropylamino)tetralin, HY-112061, RT-015429, CS-0043224, S8447, L000086, J-007140, SR-01000075571-7, 5,6,7,8-tetrahydro-7-(dipropylamino)-1-naphthalenol, BRD-A48015106-001-01-0, BRD-A48015106-004-03-0, 1-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro-, 105558-30-3, 122341-76-8, 142272-99-9, 80300-08-9

ID: 177

InChIKey: ATADHKWKHYVBTJ-UHFFFAOYSA-N
SMILES: CNCC(C1=CC(=C(C=C1)O)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5924
synonyms found at PubChem are:
329-63-5, DL-ADRENALINE HYDROCHLORIDE, 4-(1-Hydroxy-2-(methylamino)ethyl)benzene-1,2-diol hydrochloride, (+/-)-Epinephrine hydrochloride, Epinephrine hydrochloride, (+-)-Epinephrine hydrochloride, (+-)-Adrenaline hydrochloride, (+/-)-ADRENALIN HYDROCHLORIDE, Racepinephrine HCl, EINECS 206-346-0, Racepinephrine hydrochloride (USP), Racepinephrine hydrochloride [USP], 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, chloride, MLS001333244, 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride, (+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride, (+/-)-Adrenalin, SR-01000075862, SMR000058236, 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride, 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, hydrochloride (1:1), 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (1:1), IuEthyEoEIIUEO, adrenalinhydrochlorid, (1)-4-(1-Hydroxy-2-(methylamino)ethyl)pyrocatechol hydrochloride, 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride, 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, hydrochloride, 4-[1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL HYDROCHLORIDE, Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-, AC1L1LFC, AC1Q3F7B, DL-Epinephrine Hydrochloride, REGID_for_CID_5924, SCHEMBL41370, Racepinephrine/Adrenaline HCl, (y)-Epinephrine hydrochloride, MLS001333243, MLS002153388, (?)-Epinephrine hydrochloride, Jsp006067, CHEMBL1255663, MolPort-003-941-285, Tox21_500522, MFCD00050562, SBB003360, AKOS015909712, API0004027, CCG-221185, CCG-221826, LP00522, NCGC00093916-01, NCGC00261207-01, AK135317, O387, SC-17797, ST055623, AX8126389, KB-237174, A0909, EU-0100522, FT-0625414, ST24042790, X0382, D05689, E 4642, ( inverted question mark)-Adrenalin hydrochloride, ( inverted question mark)-Epinephrine hydrochloride, J-521640, SR-01000075862-1, SR-01000075862-5, I14-31836, Epinephrine dl- hydrochloride, AC1L1T5P, CTK8F1536, MolPort-000-807-126, KS-000017ZU, MCULE-9233286495, VC30860, 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, hydrochloride, LS-42885, LS-42886, BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((METHYLAMINO)METHYL)-, HYDROCHLORIDE, (+)-, A821532, J-018951, [2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-methylammonium chloride, [2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-methylazanium chloride, [2-[3,4-bis(oxidanyl)phenyl]-2-oxidanyl-ethyl]-methyl-azanium chloride, AKOS026750020

ID: 178

InChIKey: ATEBXHFBFRCZMA-VXTBVIBXSA-N
SMILES: C[C@H]1/C=C/C=C(\C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)O[C@@](C6=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)/C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6323490
synonyms found at PubChem are:
RIFABUTIN, Ansamycin, Rifabutine, Mycobutin, Ansatipine, Ansatipin, Alfacid, Rifabutina, Rifabutinum, 72559-06-9, Antibiotic LM 427, LM-427, Rifabutine [French], Rifabutinum [Latin], Rifabutina [Spanish], LM 427, Mycobutin (TN), DRG-0085, 4-N-isobutylspiropiperidylrifamycin S, Assatipin, UNII-1W306TDA6S, Rifabutin [USAN:BAN:INN], HSDB 3577, LM427, BRN 3584778, Rifabutin (JAN/USP/INN), 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV, 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S, 1W306TDA6S, RBT, CHEBI:45367, ATEBXHFBFRCZMA-VXTBVIBXSA-N, NCGC00090762-01, Rifamycin XIV, 1',4-didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxo-, DSSTox_CID_10773, DSSTox_RID_79103, DSSTox_GSID_33960, C46H62N4O11, Rifamycin XIV, 1,4-dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxo-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,18,20-trihydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethyl-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6-16,18,20-Tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethylspiro(9,4-(epoxypentadeca(1,11,13)trienimino)-2H-furo(2',3':7,8)naphth(1,2-d)imidazole-2,4'-piperidine)-5,10,26(3H,9H)-trione,16-acetate, CAS-72559-06-9, Ansamicin, Rifabutin [USAN:USP:INN:BAN:JAN], Rifabutin Pfizer Brand, Prestwick2_001109, Pfizer Brand of Rifabutin, D05CHI, Kenfarma Brand of Rifabutin, SCHEMBL36043, Grunenthal Brand of Rifabutin, MLS001061256, CHEMBL444633, DTXSID0033960, MolPort-005-938-065, HMS1571M20, HMS3259D12, HMS3715M20, Tox21_111012, Tox21_200758, AKOS015963033, ZINC169621215, CCG-221109, DB00615, Mycobutin;Ansamycin;LM 427;Ansatipine, NC00720, NCGC00090762-02, NCGC00258312-01, AC-19109, AN-37420, BC214998, SC-18287, SMR001227203, AB2000265, LS-143839, C07235, D00424, AB01209745-01, AB01274733-01, AB01274733_02, 559R069, Mycobutin, Ansamycin, LM 427, Ansatipine, Rifabutin, (trihydroxy-1'-isobutyl-methoxy-heptamethyl-trioxo-spiro[[?]-4,4'-piperidine]yl) acetate, (7S,11S,12R,13S,14R,15R,16R,17S,18S)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1;{4,7}.0;{5,31}.0;{26,30}]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6-16,18,20- TETRAHYDROXY-1'-ISOBUTYL-14-METHOXY-7,9,15,17,19,21,25- HEPTAMETHYLSPIRO(9,4-(EPOXYPENTADECA(1,11,13)TRIENIMINO)-2H- FURO(2',3':7,8)NAPHTH(1,2-D)IMIDAZOLE-2,4'-PIPERIDINE)- 5,10,26(3H,9H)-TRIONE,16-ACETATE, 1,4-dihydro-1-deoxy-1?,4-didehydro-5?-(2-methylpropyl)-1-oxo-rifamycinxi;1,4-dihydro-1-deoxy-1?,4-didehydro-5?-(2-methylpropyl)-1-oxorifamycinxiv;, Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptameth, Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-

ID: 179

InChIKey: ATEFPOUAMCWAQS-UHFFFAOYSA-N
SMILES: C1=CC(=C(C2=C1C=CC(=O)O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5280569
synonyms found at PubChem are:
daphnetin, 7,8-Dihydroxycoumarin, 486-35-1, Daphnetol, 7,8-Dihydroxy-2H-chromen-2-one, 7,8-Dihydroxy-2H-1-benzopyran-2-one, 7,8-dihydroxychromen-2-one, 7,8-DIHYDROXY-2H-BENZOPYRAN-2-ONE, UNII-XC84571RD2, 2H-1-Benzopyran-2-one, 7,8-dihydroxy-, TCMDC-125839, COUMARIN, 7,8-DIHYDROXY-, EINECS 207-632-8, NSC 633563, BRN 0009372, CHEMBL244948, CHEBI:17313, XC84571RD2, 7,8-Dihydroxycoumarin (Daphnetin), NSC633563, 7,8-DIHYDROXY-CHROMEN-2-ONE, AE-641/02519040, Q-100543, SMR001230713, SR-01000075820, 1,8-Dihydroxycoumarin, PubChem13303, 7,8-dihydroxy-coumarin, ACMC-1AKCA, SpecPlus_000864, AC1NQX8J, Spectrum3_000784, Spectrum4_001254, Lopac-D-5564, Lopac0_000330, Oprea1_044324, BSPBio_002488, Daphnetin, 486-35-1, KBioGR_001808, 5-18-03-00211 (Beilstein Handbook Reference), MLS002153288, MLS006012039, DivK1c_006960, SCHEMBL128212, 7,8-Dihydroxycoumarin, 90%, CTK1D5894, KBio1_001904, KBio3_001708, ZINC57753, 7,8-bis(oxidanyl)chromen-2-one, DTXSID00197560, ATEFPOUAMCWAQS-UHFFFAOYSA-N, MolPort-000-881-189, HMS3261A21, HMS3656G16, 7,8-dihydroxy-1-benzopyran-2-one, Tox21_500330, ANW-43482, BDBM50206006, CCG-39736, CD0136, HSCI1_000053, MFCD00016977, s2554, 7,8-Dihydroxy-2H-chromen-2-one #, AKOS000277449, FCH1116232, LP00330, MCULE-9549774136, NSC-633563, PB17055, RP09500, KS-0000122Z, 7,8-Dihydroxycoumarin, >=97%, powder, NCGC00015349-01, NCGC00015349-02, NCGC00015349-03, NCGC00015349-04, NCGC00015349-05, NCGC00015349-06, NCGC00093770-01, NCGC00093770-02, NCGC00261015-01, AK170408, AN-10899, CC-26254, KB-49571, LS-55162, OR345097, SC-13560, ZB002254, TC-132227, CS-0008778, D4001, EU-0000106, EU-0100330, FT-0603132, N1567, ST50308908, V0328, C03093, D 5564, Q-1224, 2H-1-Benzopyran-2-one, 7,8-dihydroxy- (9CI), 486D351, A827573, C-06353, SR-01000075820-1, SR-01000075820-2, BRD-K61269089-001-01-4, BRD-K61269089-001-02-2, I14-12304, InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12

ID: 180

InChIKey: AUHDSXJSHZGEIP-UHFFFAOYSA-M
SMILES: C1=CC=[N+](C=C1)C2=CC=CC=C2CO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 10846650

ID: 181

InChIKey: AUNGANRZJHBGPY-SCRDCRAPSA-N
SMILES: CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 493570
synonyms found at PubChem are:
riboflavin, vitamin B2, Lactoflavin, Riboflavine, Vitamin G, 83-88-5, Lactoflavine, (-)-riboflavin, Beflavin, Beflavine, Flavaxin, Riboflavina, Ribocrisina, Riboflavinum, Vitaflavine, Flaxain, Lactobene, Ribipca, Riboderm, Ribosyn, Ribotone, Ribovel, Flavin BB, Vitasan B2, Dermadram, Fiboflavin, Hyflavin, HYRE, Aqua-Flave, Vitamin Bi, 7,8-Dimethyl-10-ribitylisoalloxazine, Russupteridine Yellow III, 6,7-Dimethyl-9-D-ribitylisoalloxazine, E101, Riboflavinequinone, Riboflavine [INN-French], Riboflavinum [INN-Latin], Riboflavina [INN-Spanish], HSDB 817, UNII-TLM2976OFR, CCRIS 1904, CHEBI:17015, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine, Riboflavin (Vit B2), C17H20N4O6, EINECS 201-507-1, NSC 33298, TLM2976OFR, 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione, AI3-14697, Isoalloxazine, 7,8-dimethyl-10-D-ribityl-, AUNGANRZJHBGPY-SCRDCRAPSA-N, D-Ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo(g)pteridin-10(2H)-yl)-, DSSTox_CID_1777, Isoalloxazine, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-, 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol, DSSTox_RID_76321, DSSTox_GSID_21777, Ovoflavin, 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione, 7,8-dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione, Riboflavin(B2);7,8-Dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione, Benzo(g)pteridine-2,4(3H,10H)-dione, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-, Riboflavin [USP:INN:BAN], Riboflavin [USAN:INN:JAN], 1kyv, 2ccb, 2vxa, ()-Riboflavin, San Yellow B, CAS-83-88-5, NCGC00017291-05, Bisulase (TN), 13123-37-0, Food Yellow 15, Prestwick_442, Vitamin B2;E101, 2fl5, 2vx9, 4d1y, Prestwick3_000634, Riboflavin (Vitamin B2), D04QST, Epitope ID:161730, AC1LAR57, SCHEMBL7706, CHEMBL1534, Riboflavin5'-SodiumPhosphate, BSPBio_000628, MLS001066391, BPBio1_000692, GTPL6578, Riboflavin (JP17/USP/INN), (-)-Riboflavin (Vitamin B2), DTXSID8021777, BIR0613, MolPort-003-934-329, ZX-AFC000568, (-)-Riboflavin, 97-103%, HMS2096P10, Benzo[g]pteridine riboflavin deriv., HY-B0456, ZINC2036848, Tox21_110813, Tox21_111714, Tox21_201633, Tox21_302980, 6,7-Dimethyl-9-ribitylisoalloxazine, BDBM50362895, MFCD00005022, s2540, Riboflavin (B2), analytical standard, Tox21_111714_1, CS-2567, DB00140, LS-2192, RL05171, NCGC00091288-01, NCGC00091288-02, NCGC00091288-03, NCGC00091288-05, NCGC00179498-01, NCGC00256408-01, NCGC00259182-01, AS-15936, R437, SMR000112236, AB0008077, AB2000637, ST2413784, R0020, (-)-Riboflavin, tested according to Ph.Eur., C00255, D00050, Y-9791, (-)-Riboflavin, meets USP testing specifications, A840676, (-)-Riboflavin, from Eremothecium ashbyii, >=98%, (-)-Riboflavin, acrylamide photopolymerization tested, Riboflavin, European Pharmacopoeia (EP) Reference Standard, Riboflavin, United States Pharmacopeia (USP) Reference Standard, Riboflavin, Pharmaceutical Secondary Standard; Certified Reference Material, 5-deoxy-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol, 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione, Riboflavin for peak identification, European Pharmacopoeia (EP) Reference Standard, (-)-Riboflavin (Vitamin B2) solution, 100 mug/mL (Methanol:0.1% Ammonium acetate in Water (1:1)), ampule of 1 mL, analytical standard, (-)-Riboflavin, BioReagent, suitable for cell culture, suitable for insect cell culture, >=98%, 130609-39-1, 535950-32-4, 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione, 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrakis(oxidanyl)pentyl]benzo[g]pteridine-2,4-dione, 890044-91-4, InChI=1/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s

ID: 182

InChIKey: AUZONCFQVSMFAP-UHFFFAOYSA-N
SMILES: CCN(CC)C(=S)SSC(=S)N(CC)CC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3117
synonyms found at PubChem are:
disulfiram, Tetraethylthiuram disulfide, 97-77-8, Antabuse, Alcophobin, Antabus, Anticol, Bis(diethylthiocarbamoyl) disulfide, Esperal, Teturam, TETD, Dicupral, Exhorran, Hoca, Ethyldithiurame, Abstensil, Antaethyl, Antietanol, Antivitium, Contralin, Tetradine, Tetraetil, Teturamin, Abstinil, Abstinyl, Antadix, Antalcol, Antetan, Antetil, Antietil, Antikol, Aversan, Averzan, Cronetal, Krotenal, Refusal, Etabus, Ethyl tuads, Ethyl Thiram, Ethyl Thiurad, Ethyl Tuex, Antaenyl, Antaetil, Antiaethan, Contrapot, Disulfan, Disulfuram, Ephorran, Stopetyl, Thiuranide, Anteyl, Bonibal, Disetil, Nocbin, Tenurid, Tenutex, Tetidis, Ekagom TEDS, Ekagom TETDS, Ethyldithiourame, Noxal, Anti-ethyl, Alk-aubs, Thiuram E, TATD, Soxinol TET, Tetraethylthiram disulfide, Ekagom DTET, Accel TET, Espenal, Exhoran, Sanceler TET-G, Ro-sulfiram, Tetraethylthiuram disulphide, Tetraethylthiuram, Tuads, ethyl, Usaf B-33, Sanceler TET, Tetraethylthioperoxydicarbonic diamide, Stopaethyl, Thireranide, Antaethan, Antethyl, Tetradin, Tillram, Accel TET-R, Ethyl Thiudad, Dupon 4472, Tetraethylthiuran disulfide, Nocceler TET, Nocceler TET-G, Anthethyl, Disulphuram, Stopethyl, Dupont fungicide 4472, Hocakrotenalnci-C02959, Tetraethylthiram disulphide, Esperal [France], Antivitium (Spain), Disulfirame, Disulfiramo, Disulfiramum, Disulfirame [DCIT], Nocceler, Stopety, THIOCID, Noxal (VAN), Ancazide ET, Etyl Tuex, Tetraethylthiuram sulfide, Thiuram disulfide, tetraethyl-, Akrochem TETD, Perkacit TETD, Ekaland TETD, Perkait TETD, N,N,N',N'-Tetraethylthiuram disulfide, Antabuse (TN), Bis(N,N-diethylthiocarbamoyl) disulfide, Bis(diethylthiocarbamyl) disulfide, Ethyl Tuads Rodform, Ro-Sulfram-500 (USA), 1,1'-Dithiobis(N,N-diethylthioformamide), Disulfide, bis(diethylthiocarbamoyl), Abstensyl (Argentina), Refusal [Netherlands], Abstenisil, Antiethanol, Gababentin, Disulfirm, Disulfram, ENT 27,340, TTD, UNII-TR3MLJ1UAI, Antab use, Thioperoxydicarbonic diamide, tetraethyl-, Bis(diethylthiocarbamoyl)disulphide, Eta bus, NCI-C02959, Disulfiramum [INN-Latin], tet raethylthiuram, Tetraethylthiurium disulfide, Disulfiramo [INN-Spanish], Robac TET, CCRIS 582, NSC 190940, Bis(N,N-diethylthiocarbamoyl)disulphide, N,N,N',N'-Tetraethylthiuram disulphide, Bis((diethylamino)thioxomethyl)disulphide, Bis((diethylamino)thioxomethyl) disulfide, TTS, TTS x, Disulfiram (Antabuse), HSDB 3317, AUZONCFQVSMFAP-UHFFFAOYSA-N, diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate, C10H20N2S4, TR3MLJ1UAI, EINECS 202-607-8, NSC 25953, NSC-25953, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetraethyl-, CHEMBL964, AI3-27340, MLS000069818, CHEBI:4659, N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide, Formamide, 1,1'-dithiobis(N,N-diethylthio-, NSC25953, CAS-97-77-8, NCGC00016000-08, NCGC00016000-13, CPD000059171, SMR000059171, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl-, 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane, DSSTox_CID_1322, Formamide, 1,1'-dithiobis(N,N-diethylthio)-, T 1132, DSSTox_RID_76082, DSSTox_GSID_21322, Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetraethyl-, 1,1',1'',1'''-[dithiobis(carbonothioylnitrilo)]tetraethane, Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N',N'-tetraethyl-, Bis[(diethylamino)thioxomethyl] disulfide, 1,1'-Dithiobis[N,N-diethylthioformamide], SR-01000076145, ethylthiudad, ethyltuex, Disulfarim, Antabuse;Antabus, Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetraethyl-, Disulfiram [USP:INN:BAN:JAN], Prestwick_182, Antabus (TN), Spectrum_001010, Opera_ID_224, AC1Q2YXI, Prestwick0_000097, Prestwick1_000097, Prestwick2_000097, Prestwick3_000097, Spectrum2_001176, Spectrum3_000405, Spectrum4_000228, Spectrum5_001590, Lopac-T-1132, 1,N-diethylthioformamide], D0X5SD, UPCMLD-DP090, EC 202-607-8, tetraethyl thiuram disulfide, AC1L1F7H, Tetraethyldithiuram disulfide, Lopac0_001164, SCHEMBL27213, BSPBio_000054, BSPBio_001930, KBioGR_000895, KBioSS_001490, KSC491K6T, MLS000758264, MLS001076475, MLS001423963, ARONIS24121, SPECTRUM1500262, SPBio_001191, SPBio_001993, ACMC-209s92, BPBio1_000060, Disulfiram (JP17/USP/INN), GTPL7168, DTXSID1021322, UPCMLD-DP090:001, CTK3J1569, KBio2_001490, KBio2_004058, KBio2_006626, KBio3_001150, Bis(diethylthiocarbamyoyl)disulfide, MolPort-001-792-519, HMS1568C16, HMS1920I16, HMS2051M17, HMS2090C18, HMS2091O22, HMS2095C16, HMS2230K06, HMS3263J09, HMS3371B21, HMS3393M17, HMS3655I19, HMS3712C16, Pharmakon1600-01500262, BCP07331, HY-B0240, KS-000011OS, KS-000046JU, ZINC1529266, bis-(diethyl-thiocarbamyl)-disulfide, Tox21_110280, Tox21_300403, Tox21_400072, Tox21_501164, ANW-40884, BDBM50058655, CCG-39549, DL-379, MFCD00009048, N,N',N'-Tetraethylthiuram disulfide, NSC756748, s1680, SBB058706, STL069539, 1,1',1'',1'''-{disulfanediylbis[(thioxomethylene)nitrilo]}tetraethane, AKOS000120201, Tox21_110280_1, CS-2209, DB00822, HS-0057, LP01164, LS-2031, MCULE-1443050857, NC00063, NSC-756748, RTR-030253, WLN: 2N2 & YUS & S 2, 1,1;-Dithiobis(N,N-diethylthioformamide, NCGC00016000-01, NCGC00016000-02, NCGC00016000-03, NCGC00016000-04, NCGC00016000-05, NCGC00016000-06, NCGC00016000-07, NCGC00016000-09, NCGC00016000-10, NCGC00016000-11, NCGC00016000-12, NCGC00016000-14, NCGC00016000-15, NCGC00016000-18, NCGC00094423-01, NCGC00094423-02, NCGC00094423-03, NCGC00094423-05, NCGC00094423-06, NCGC00094423-07, NCGC00254447-01, NCGC00261849-01, AN-24463, CJ-05170, CJ-23871, KB-81054, N,N,N'',N''-tetraethylthiuram disulfide, R531, SAM001247028, SC-75356, Tetraethylthiuram disulfide, 97% 250g, Formamide,1'-dithiobis(N,N-diethylthio)-, SBI-0051131.P004, 1,1''-dithiobis(N,N-diethylthioformamide), AB2000216, TR-030253, AB00051976, B0479, EU-0101164, FT-0631502, Tetraethylthiuram disulfide, >=97.0% (S), W0030, C01692, D00131, S00294, Z-0809, AB00051976-20, AB00051976-21, AB00051976-23, AB00051976_22, AB00051976_25, A845750, Q-201812, SR-01000076145-1, SR-01000076145-5, SR-01000076145-8, BRD-K32744045-001-05-6, BRD-K32744045-001-17-1, I14-53917, Z1522553469, Disulfiram, European Pharmacopoeia (EP) Reference Standard, 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetra, 1-(diethylthiocarbamoyldisulfanyl)-N,N-diethyl-methanethioamide, Disulfiram, United States Pharmacopeia (USP) Reference Standard, (diethylamino){[(diethylamino)thioxomethyl]disulfanyl}methane-1-thione, 1,1'',1'''',1''''''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane, 1,1',1'',1'''-{disulfanediylbis[(thioxomethylene)-nitrilo]}tetraethane, Disulfiram, Pharmaceutical Secondary Standard; Certified Reference Material, N,N-diethylcarbamodithioic acid [[diethylamino(sulfanylidene)methyl]thio] ester, 11078-22-1, 155-01-1, InChI=1/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H

ID: 183

InChIKey: AVOLMBLBETYQHX-UHFFFAOYSA-N
SMILES: CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3278
synonyms found at PubChem are:
ETHACRYNIC ACID, Etacrynic Acid, ethacrynate, Etacrinic acid, 58-54-8, Hydromedin, Edecrin, Crinuryl, Edecril, Edecrina, Endecril, Hidromedin, Otacril, Taladren, Mingit, Reomax, Uregit, Etakrinic acid, Methylenebutyrylphenoxyacetic acid, Acido etacrinico, Acide etacrynique, Acidum etacrynicum, MK-595, Ethacrinique (acide), Kyselina ethakrynova, Ethacrinic acid, Kyselina ethakrynova [Czech], Ethacryinic Acid, Acide etacrynique [INN-French], Acido etacrinico [INN-Spanish], Acidum etacrynicum [INN-Latin], (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid, Methylenebutyryl phenoxyacetic acid, [2,3-Dichloro-4-(2-methylenebutyryl)phenoxy]acetic acid, Ethacrynic acid [USAN:BAN], 2,3-Dichloro-4-(2-methylenebutyl)phenoxyacetic acid, UNII-M5DP350VZV, MK 595, NSC 85791, Ethacrynic Acid, Sodium Salt, NSC 624008, C13H12Cl2O4, BRN 1915060, CCRIS 4638, 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, HSDB 2136, Ethacrynic acid (USP), 2,3-Dichloro-4-(2-methylenebutyryl)phenoxy acetic acid, (2,3-Dichloro-4-(2-methylenebutyryl)phenoxy)acetic acid, (4-(2-Methylenebutyryl)-2,3-dichlorophenoxy)acetic acid, EINECS 200-384-1, 2-(2,3-Dichloro-4-(2-methylenebutanoyl)phenoxy)acetic acid, CHEMBL456, Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-, Acetic acid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, Kyselina 4-(2-(1-butenyl)karbonyl)-2,3-dichlorfenoxyoctova [Czech], M5DP350VZV, MLS000069535, MLS002701928, CHEBI:4876, Kyselina 4-(2-(1-butenyl)karbonyl)-2,3-dichlorfenoxyoctova, Acetic acid, (2,3-dichloro-4-(2-methylenebutyryl)phenoxy)-, AVOLMBLBETYQHX-UHFFFAOYSA-N, NSC85791, NSC624008, CAS-58-54-8, [4-(2-Methylenebutyryl)-2,3-dichlorophenoxy]acetic acid, NCGC00016260-05, Sodium ethacrynate, [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, SMR000058600, [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic acid, E0526, DSSTox_CID_5257, DSSTox_RID_77718, DSSTox_GSID_25257, 2,3-Dichloro-4-(2-methylenebutyryl)phenoxyacetic acid, [2,3-dichloro-4-(2-methylenebutanoyl)phenoxy]acetic acid, 2,3-Dichloro-4(2-methylene-butyryl)phenoxy] acetic acid, 2-[2,3-dichloro-4-(2-methylenebutanoyl)phenoxy]acetic acid, SR-01000003010, (2,3-Dichloro-4-[2-methylenebutyryl]phenoxy)acetic acid, Etacrynsaure, Crinuril, Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-, Ethacrynic acid [USAN:USP], Etacynic acid, 1gsf, 2gss, Prestwick_671, Edecrin (TN), Opera_ID_61, Etacrynic acid [INN], Spectrum_000813, AC1L1FKN, Prestwick0_000259, Prestwick1_000259, Prestwick2_000259, Prestwick3_000259, Spectrum2_000097, Spectrum3_000425, Spectrum4_000544, Spectrum5_000680, bmse000134, D06TNL, SCHEMBL26353, BSPBio_000078, BSPBio_002010, KBioGR_001207, KBioSS_001293, MLS002548854, DivK1c_000900, Etacrynic acid (JP15/INN), Etacrynic acid (JP17/INN), SPECTRUM1500287, SPBio_000054, SPBio_002297, BPBio1_000086, GTPL7179, ZINC1382, DTXSID3025257, CTK3J2058, HMS502M22, KBio1_000900, KBio2_001293, KBio2_003861, KBio2_006429, KBio3_001230, MolPort-003-666-185, NINDS_000900, HMS1568D20, HMS1920M16, HMS2089N17, HMS2091D17, HMS2095D20, HMS3259G03, HMS3712D20, Pharmakon1600-01500287, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic acid, KS-000017ZX, 6500-81-8 (hydrochloride salt), Ethacrynic acid, >=97% (HPLC), Tox21_110335, Tox21_201102, BDBM50186231, CCG-38915, LS-240, NSC-85791, NSC757026, WLN: QV1OR BG CG DVY2&U1, AKOS003404732, Tox21_110335_1, API0002520, DB00903, KS-1453, MCULE-6140194266, NC00450, NSC-624008, NSC-757026, RTR-020341, IDI1_000900, NCGC00016260-01, NCGC00016260-02, NCGC00016260-03, NCGC00016260-04, NCGC00016260-06, NCGC00016260-07, NCGC00016260-08, NCGC00016260-09, NCGC00016260-10, NCGC00016260-11, NCGC00016260-13, NCGC00022601-03, NCGC00022601-04, NCGC00022601-05, NCGC00258654-01, AN-16719, CC-27538, CPD000058600, NCI60_041898, SAM002264611, SC-34221, SC-74303, SBI-0051374.P003, KB-226863, TR-020341, AB00051988, CS-0013591, FT-0603245, V0310, D00313, AB00051988-19, AB00051988_20, A831918, C-18899, SR-01000003010-2, SR-01000003010-3, BRD-K63630713-001-05-0, BRD-K63630713-001-15-9, [2,3-Dichloro-4-(2-ethylacryloyl)phenoxy]acetic acid #, Acetic acid,3-dichloro-4-(2-methylenebutyryl)phenoxy]-, 2,3-Dichloro-4(2-methylene- butyryl)phenoxy] acetic acid, N-ALPHA-CARBOBENZOXY-L-ASPARTIC ACID ALPHA-T-BUTYL, Acetic acid,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, Ethacrynic acid, European Pharmacopoeia (EP) Reference Standard, Ethacrynic acid, United States Pharmacopeia (USP) Reference Standard, 2-[2,3-bis(chloranyl)-4-(2-methylidenebutanoyl)phenoxy]ethanoic acid, Etacrynic acid for system suitability, European Pharmacopoeia (EP) Reference Standard

ID: 184

InChIKey: AVZIYZHXZAYGJS-UHFFFAOYSA-N
SMILES: C1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66266
synonyms found at PubChem are:
3254-89-5, Diphenidol hydrochloride, difenidol hydrochloride, 1,1-Diphenyl-4-(piperidin-1-yl)butan-1-ol hydrochloride, Diphenidol HCl, Celmidol, Satanolon, Verterge, Ansmin, Cerrosa, Maniol, Yesdol, 1,1-Diphenyl-4-piperidino-1-butanol hydrochloride, Difenidolin, Cefadol, Mecalmin, Pineroro, Tenesdol, Wansar, SKF 478 hydrochloride, Diphenidol (hydrochloride), SK&F 478-A, UNII-DG355XWQ4T, 2C64, Diphenidol hydrochloride [USAN], SKF 478-A, EINECS 221-850-0, NSC 23012, DG355XWQ4T, MLS000069816, 1,1-diphenyl-4-(1-piperidyl)butan-1-ol hydrochloride, alpha,alpha-Diphenyl-1-piperidinebutanol hydrochloride, alpha,alpha-Diphenylpiperidine-1-butanol hydrochloride, 1-Piperidinebutanol, alpha,alpha-diphenyl, hydrochloride, SMR000058238, alpha, alpha-Diphenyl-1-piperidine butanol, C21H28ClNO, 1,1-DIPHENYL-4-(PIPERIDIN-1-YL)BUTAN-1-OL HCL, Diphenidol hydrochloride (USAN), SK&F-478A, 1,1-diphenyl-4-piperidylbutan-1-ol, chloride, 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol;hydrochloride, Difenidol, HCl, Cephadol (TN), Prestwick_886, Vontrol (TN), ACMC-209htu, Opera_ID_631, AC1L24ZR, CHEMBL1529, Difenidol Hydrochloride,(S), MLS002222273, SCHEMBL195192, 972-02-1 (Parent), Difenidol hydrochloride (JP17), CHEBI:31481, CTK8B1460, DTXSID10186248, MolPort-003-941-110, HMS1568D06, BCP13983, HY-A0082, KS-000015TY, NSC23012, SK-478-A, AC-335, ANW-27376, NSC-23012, s4292, SBB006449, 1,1-Diphenyl-4-piperidino-1-butanol, AKOS007930367, CCG-220252, DS-1389, MCULE-4932461593, TRA0068246, AN-15938, BC200594, BR-64514, ST055883, AB0011648, KB-216131, LS-114372, ST2408401, TR-013669, 4CH-010474, FT-0667646, D01318, S-4785, 1,1-Diphenyl-4-piperidino-1-butanolHydrochloride, 254D895, SR-01000721935, 1-Piperidinebutanol,.alpha.-diphenyl, hydrochloride, 1-Piperidinebutanol,.alpha.-diphenyl-, hydrochloride, J-018780, SR-01000721935-2, Z57257314, 1-(4-Hydroxy-4,4-diphenylbutyl)piperidine Hydrochloride, Butanol,1,1-diphenyl-4-(1-piperidyl)-, hydrochloride, .alpha.,.alpha.-Diphenyl-1-piperidinebutanol hydrochloride, 1-Piperidinebutanol, alpha,alpha-diphenyl-, hydrochloride, 1,1- paragraph signthorn+/-(1/2)>>u-4-(1-ssssa currency>>u)-1- paragraph sign inverted exclamation mark (1/4), SCHEMBL15531902, AKOS026749965

ID: 185

InChIKey: AWEFUQDNSBBNCR-UHFFFAOYSA-N
SMILES: CC(=CCOC1=C(C=C2C=CC(=O)OC2=C1)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3873459
synonyms found at PubChem are:
PRENYLETIN, 6-hydroxy-7-(3-methylbut-2-enoxy)chromen-2-one, 15870-91-4, KBio2_003658, AC1MZJHM, Spectrum_000610, SpecPlus_000123, Spectrum2_000250, Spectrum3_000034, Spectrum4_001315, Spectrum5_000129, BSPBio_001727, KBioGR_001749, KBioSS_001090, SPECTRUM100101, DivK1c_006219, SPBio_000040, CHEMBL607536, SCHEMBL12062090, KBio1_001163, KBio2_001090, KBio2_006226, KBio3_000867, CCG-39811, SDCCGMLS-0066355.P001, NCGC00095380-01, NCGC00095380-02, SR-05000002493, SR-05000002493-1, BRD-K81750404-001-02-5, BRD-K81750404-001-03-3, 6-hydroxy-7-((3-methylbut-2-en-1-yl)oxy)-2H-chromen-2-one

ID: 186

InChIKey: AXBHPHPHZHAOAK-UHFFFAOYSA-N
SMILES: CCN(CC)CCNC(=O)COC1=CC=C(C=C1)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3083802
synonyms found at PubChem are:
Mefexamide hydrochloride, UNII-M00ED8AW1S, M00ED8AW1S, 3413-64-7, NCGC00094894-01, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)acetamide hydrochloride, DSSTox_CID_25862, DSSTox_RID_81182, DSSTox_GSID_45862, p-Methoxyphenoxyacetic acid 2-[diethylamino]ethylamide, CAS-3413-64-7, SR-01000797216, Prestwick_585, EINECS 222-304-4, AC1MJ1BB, MLS002154238, SCHEMBL364170, SPECTRUM1501108, CHEMBL1448010, DTXSID2045862, 1227-61-8 (Parent), MolPort-002-322-455, HMS1568L11, HMS1921D19, Pharmakon1600-01501108, Tox21_111353, CCG-39017, NSC757827, AKOS026677721, N-(2-(Diethylamino)ethyl)-2-(4-methoxyphenoxy)acetamide monohydrochloride, Tox21_111353_1, MCULE-9428274814, NSC-757827, NCGC00016626-04, NCGC00094894-02, SMR001233509, SR-01000797216-4, F0349-0264, Mefexamide hydrochloride, analytical standard, for drug analysis, N-(2-diethylaminoethyl)-2-(4-methoxyphenoxy)acetamide hydrochloride, AKOS026749852

ID: 187

InChIKey: AXEGYQIJLMUXKW-UHFFFAOYSA-N
SMILES: C1=CN=C(N=C1)NC2=NC(=CS2)C3=CC(=C(C=C3)O)O

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 751856
synonyms found at PubChem are:
MLS000715725, 4-[2-(pyrimidin-2-ylamino)-1,3-thiazol-4-yl]benzene-1,2-diol, SMR000277242, AC1LFD7J, Oprea1_396000, SCHEMBL837838, CHEMBL240333, cid_751856, BDBM50504, MolPort-001-998-511, HMS2625L11, KUC106812N, ZINC202220, CCG-22209, STK066459, AKOS000563358, MCULE-8776135083, BAS 04880533, KSC-11-237-16, 4-[2-(2-pyrimidylamino)thiazol-4-yl]pyrocatechol, 4-[2-(2-pyrimidinylamino)-4-thiazolyl]benzene-1,2-diol, 4-[2-(pyrimidin-2-ylamino)thiazol-4-yl]benzene-1,2-diol, 1,2-Benzenediol, 4-[2-(2-pyrimidinylamino)-4-thiazolyl]-, 4-[2-(Pyrimidin-2-ylamino)-thiazol-4-yl]-benzene-1,2-diol

ID: 188

InChIKey: AXNVHPCVMSNXNP-LGWBRZJHSA-N
SMILES: C/C=C(/C)\C(=O)O[C@@H]1[C@@H]([C@@]2([C@@H](C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CC[C@@H]([C@]5(C)CO)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6857783
synonyms found at PubChem are:
SR-05000002789, 11072-93-8, Spectrum5_000767, AC1OAH74, BSPBio_002814, SPECTRUM1504030, SCHEMBL18947797, HMS1922B05, Pharmakon1600-01504030, CCG-38719, NSC758653, NSC-758653, SDCCGMLS-0066819.P001, NCGC00178455-01, SBI-0052420.P002, AB00052928_02, SR-05000002789-1, SR-05000002789-2, (2S,3S,4S,5R,6R)-6-[[(3S,4S,6aR,6bS,8R,8aR,9R,10S,14bR)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid

ID: 189

InChIKey: AXOJRQLKMVSHHZ-UHFFFAOYSA-N
SMILES: CN1CCC=C(C1)C(=O)OC.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9301
synonyms found at PubChem are:
Arecoline hydrobromide, 300-08-3, Arecoline bromide, ARECOLINE HBr, Taeniolin, Methyl 1-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide, Arecoline (hydrobromide), Arekolinhydrobromid [German], UNII-24S79B9CX7, EINECS 206-087-3, NSC 31750, methyl 1,2,5,6-tetrahydro-1-methylnicotinate hydrobromide, N-Methyltetrahydronicotinic acid methyl ester hydrobromide, 24S79B9CX7, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide, Methyl N-methyl-1,2,5,6-tetrahydronicotinate hydrobromide, Methyl 1,2,5,6-tetrahydro-1-methylnicotinate, hydrobromide, C8H14BrNO2, MLS000028840, 3-Pyridinecarboxylicacid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate hydrobromide, Arekolinhydrobromid, 1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide, 3-Pyridinecarboxylicacid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide, NICOTINIC ACID, 1,2,5,6-TETRAHYDRO-1-METHYL-, METHYL ESTER, HYDROBROMIDE, NSC31750, SR-01000075307, SMR000058258, Arecoline hydrobromide [NF], methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate, bromide, Prestwick_958, AC1L1SRM, AC1Q5YLK, ARECOLINIUM BROMIDE, C8H13NO2.HBr, Areciline Hydrochloride,(S), MLS002222282, ARECOLINE, HYDROBROMIDE, SCHEMBL527735, SPECTRUM1500680, CHEMBL449209, METHYL 1,2,5, DTXSID9075379, CTK5B9809, AXOJRQLKMVSHHZ-UHFFFAOYSA-N, MolPort-001-742-600, HMS1569A06, HMS1921C10, Pharmakon1600-01500680, METHYLARECAIDINE HYDROBROMIDE, Arecaidine methyl ester hydrobromide, BCP02923, HY-B0489, Tox21_500049, CCG-38354, NSC-31750, NSC757418, s2614, SBB053837, AKOS009031332, AC-8048, AN-8402, BCP9000314, CS-2605, LP00049, MCULE-7834041957, NE10937, NSC-757418, PS-7647, KS-0000017W, WLN: T6N CUTJ A1 CVO1 & GH, NCGC00093563-01, NCGC00093563-02, NCGC00093563-03, NCGC00093563-04, NCGC00093563-05, NCGC00093563-06, NCGC00260734-01, KB-47433, L984, LS-96625, BCP0726000295, AB0014990, AB2000702, ST2406633, A0523, AM20090404, EU-0100049, FT-0628354, ST50307303, A 6134, J10116, I04-0232, Q-100382, SR-01000075307-1, SR-01000075307-3, SR-01000075307-8, SR-01000075307-10, SR-01000075307-11, Methyl N-methyl-1,5,6-tetrahydronicotinate hydrobromide, Arecoline hydrobromide, VETRANAL(TM), analytical standard, Methyl 1,5,6-tetrahydro-1-methylnicotinate, hydrobromide, Methyl 1-methyl-1,2,5,6-tetrahydronicotinate hydrobromide, methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate,hydrobromide, Methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide, Nicotinic acid,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide, 1,2,5,6-TETRAHYDRO-1-METHYL-3-PYRIDINECARBOXYLIC ACID METHYL ESTER, MONOHYDROBROMIDE, 3-(METHOXYCARBONYL)-1-METHYL-1,2,5,6-TETRAHYDROPYRIDINE HYDROBROMIDE, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (9CI), 3-Pyridinecarboxylic acid,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide, AKOS026750381

ID: 190

InChIKey: AXRUEPFPTQYHQD-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107966
synonyms found at PubChem are:
NAN-190 hydrobromide, 115388-32-4, 115338-32-4, 2-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)isoindoline-1,3-dione hydrobromide, NAN-190, NAN 190 hydrobromide, NAN-190 (hydrobromide), CHEBI:64123, 1-(2-Methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine hydrobromide, 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazinehydrobromide, 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide, 1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide, 2-(4-(4-(2-METHOXYPHENYL)PIPERAZIN-1-YL)BUTYL)-ISOINDOLINE-1,3-DIONE HYDROBROMIDE, 2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]isoindole-1,3-dione hydrobromide, 2-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-1H-isoindole-1,3(2H)-dione hydrobromide, 1H-Isoindole-1,3(2H)-dione, 2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-, monohydrobromide, SR-01000075563, 2-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}isoindole-1,3-dione hydrobromide, NAN190 hydrobromide, C23H28BrN3O3, MLS000859948, AC1L332K, SCHEMBL4083153, CHEMBL1256701, DTXSID5042588, CTK8B9474, MolPort-003-958-974, Tox21_500876, 2511AA, ANW-62583, BN0367, CN-027, HY-19818A, MFCD00078590, AKOS016004193, CCG-222180, CS-5473, EBD2206388, LP00876, NCGC00094200-01, NCGC00261561-01, AC-27421, LS-84602, SMR000326807, AX8233420, KB-222072, KB-282405, RT-014661, TX-011461, B6349, EU-0100876, FT-0764658, ST24039357, N 3529, J-003283, SR-01000075563-1, SR-01000075563-3, 1-[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]-4-(2-methoxyphenyl)piperazin-1-ium bromide

ID: 191

InChIKey: AXXBADPZGFAAHF-ZDUSSCGKSA-N
SMILES: COC1=C(C2=C(C[C@@H](CO2)C3=C(C(=C(C=C3)OC)OC)OC)C=C1)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708574
synonyms found at PubChem are:
DUARTIN, DIMETHYL ETHER, KBio2_006389, Spectrum_000773, SpecPlus_000151, AC1O8FDW, Spectrum2_000180, Spectrum3_000215, Spectrum4_001621, Spectrum5_000401, BSPBio_001829, KBioGR_002021, KBioSS_001253, SPECTRUM201364, DivK1c_006247, SPBio_000079, CHEMBL3039229, SCHEMBL12998321, KBio1_001191, KBio2_001253, KBio2_003821, KBio3_001329, CHEBI:113530, CCG-38388, SDCCGMLS-0066408.P001, SR-05000002618, SR-05000002618-1, BRD-K87798455-001-02-6, BRD-K87798455-001-03-4, (3R)-7,8-dimethoxy-3-(2,3,4-trimethoxyphenyl)-3,4-dihydro-2H-chromene

ID: 192

InChIKey: AXXYLTBQIQBTES-BYPYZUCNSA-N
SMILES: C1=C(C(=O)NC(=O)N1C[C@@H](C(=O)O)N)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 447196
synonyms found at PubChem are:
IODO-WILLARDIINE, S-5-Iodowillardiine, (S)-(-)-5-IODOWILLARDIINE, (s)-5-iodowillardiine, 140187-25-3, CHEMBL121915, 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, IWD, 5 Iodowillardine, 5-iodowillardiine, 1mqg, Tocris-0307, AC1L9KKQ, D01DMS, Lopac0_001239, SCHEMBL401659, GTPL4071, SCHEMBL13319969, DTXSID90332246, MolPort-006-069-040, ZINC2047688, BDBM50060627, AKOS024457411, CCG-205313, DB02818, NCGC00024529-01, NCGC00024529-02, B6252, EU-0101239, W-110, SR-01000075424, SR-01000597629, J-007367, SR-01000075424-1, SR-01000597629-1, (s)-1-(2-amino-2-carboxyethyl)-5-iodopyrimidine-2,4-dione, (2S)-2-amino-3-(5-iodo-2,4-dioxopyrimidin-1-yl)propanoic acid, (2S)-2-amino-3-(5-iodo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid, (S)-2-Amino-3-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propionic acid, (S)-2-amino-3-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid, (S)-alpha-Amino-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid, 1(2H)-Pyrimidinepropanoicacid, a-amino-3,4-dihydro-5-iodo-2,4-dioxo-,(aS)-, 1(2H)-Pyrimidinepropanoicacid,a-amino-3,4-dihydro-5-iodo-2,4-dioxo-,(as)-

ID: 193

InChIKey: AYIRNRDRBQJXIF-NXEZZACHSA-N
SMILES: CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 114811
synonyms found at PubChem are:
Florfenicol, 73231-34-2, Nuflor, (-)-Florfenicol, Sch-25298, 76639-94-6, Nuflor gold, Sch 25298, florphenicol, Aquafen, C12H14Cl2FNO4S, Florfenicol [USAN:INN:BAN], UNII-9J97307Y1H, CHEBI:87185, 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide, 9J97307Y1H, 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide, D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide, DSSTox_CID_25500, DSSTox_RID_80918, DSSTox_GSID_45500, 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, 2,2-Dichloro-N-((alphaS,betaR)-alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide, 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, 81588-76-3, Acetamide, 2,2-dichloro-N-((1S,2R)-1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, Acetamide, 2,2-dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R-(R*,S*))-, Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, methyl ester, (R-(R*,S*))-, NCGC00016922-01, CAS-73231-34-2, Nuflor (TN), 3-fluorothiamphenicol, PubChem13648, thiamphenicol, 3-fluoro, AC1L3FZT, AC1Q4GHG, Prestwick0_000955, Prestwick1_000955, Prestwick2_000955, Prestwick3_000955, Florfenicol (USAN/INN), SCHEMBL49425, BSPBio_000950, MLS002154071, SPBio_003099, BPBio1_001046, CHEMBL1241590, DTXSID9045500, AYIRNRDRBQJXIF-NXEZZACHSA-N, D-(-)-threo-2-Dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol, MolPort-003-847-382, HMS1570P12, HMS2090I10, HMS2097P12, HMS2230K18, HMS3714P12, ZINC537733, ACT06682, HY-B1374, KS-00000G9G, Aquafen|||Nuflor|||SCH-25298, Tox21_110683, AN-869, MFCD00864834, s4201, AKOS015889457, Tox21_110683_1, AC-4340, API0002713, CCG-220955, CS-4857, KS-5028, NCGC00179366-01, NCGC00179366-03, NCGC00179366-04, BC203726, KB-67110, LS-31853, SC-16844, SC-59762, SMR001233384, AB0008500, AB1009284, KB-334571, (methylsulfonyl)phenyl)propan-2-yl)acetamide, AB00513976, F0811, FT-0630821, FT-0630848, D04194, J10454, AB00513976_09, 231F342, A838774, Florfenicol, analytical standard, for drug analysis, I09-1318, BRD-K11298197-001-03-9, 2,2-dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-, (1R,2S)-2-DICHLOROACETAMIDO-3-FLUORO-1-[4-(METHYLSULFONYL) PHENYL]-1-PROPANOL, (1R,2S)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol, 2,2-bis(chloranyl)-N-[(1R,2S)-3-fluoranyl-1-(4-methylsulfonylphenyl)-1-oxidanyl-propan-2-yl]ethanamide, 2,2-Dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide, 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-(4-methylsulfonylphenyl)ethyl]acetamide, 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide, Aquafen; Nuflor; SCH-25298; [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-,methyl ester, (R-(R*,S*))-

ID: 194

InChIKey: AYXYPKUFHZROOJ-ZETCQYMHSA-N
SMILES: CC(C)C[C@@H](CC(=O)O)CN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5486971
synonyms found at PubChem are:
Pregabalin, 148553-50-8, Lyrica, (S)-3-(Aminomethyl)-5-methylhexanoic acid, 3-isobutyl GABA, (3S)-3-(aminomethyl)-5-methylhexanoic acid, CI-1008, (S)-Pregabalin, CI 1008, (R-)-3-isobutyl GABA, Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-, UNII-55JG375S6M, PD 144723, PD-144723, (S)-3-Isobutyl GABA, CHEMBL1059, CHEBI:64356, (3S)-3-(aminomethyl)-5-methyl-hexanoic acid, AYXYPKUFHZROOJ-ZETCQYMHSA-N, 55JG375S6M, Hexanoic acid, 3-(aminomethyl)-5-methyl-, (S)-, (S)-3-(Aminomethyl)-5-methylhexanoicacid, Hexanoic acid, 3-(aminomethyl)-5-ethyl-, (3S)-, Pregabalin [USAN], gabanext, maxgalin, Nervalin, Pregablin, pregabalin HCl, Pregabalin CR, HSDB 7530, Pregabalin [USAN:INN:BAN:JAN], NCGC00095186-01, Lyrica (TN), pregabalin hydrochloride, S-(+)-3-isobutylgaba, D00WUF, AC1NUP03, SCHEMBL8227, DSSTox_CID_25950, DSSTox_RID_81246, DSSTox_GSID_45950, KSC005O6P, Pregabalin (JAN/USAN/INN), (S)-(+)-4-amino-3-(2-methylpropyl)butanoic acid, GTPL5484, ZINC5152, DEA No. 2782, Pregabalin, >=97% (NMR), DTXSID1045950, CTK9A5767, TOS-BB-0910, HMS3715J16, Pregabalin 1.0 mg/ml in Methanol, KS-00000AF5, Tox21_111475, BDBM50164279, CP0100, MFCD00917044, Pregabalin (controlled-release, oral), AKOS001476611, AKOS005145504, AC-1158, ACN-038395, AN-1059, CCG-221247, CM14412, CS-1247, DB00230, KS-5378, (S)-3-aminomethyl-5-methylhexanoic acid, NCGC00346738-01, 121GE001, AJ-08241, BC634849, HY-17414, KB-01630, LS-75191, SC-11867, (S)-3-Aminomethyl-5-methyl-hexanoic acid, AB0074009, AB1008692, ST2408318, TL8001062, AM20080369, CAS-148553-50-8, FT-0080911, EN300-92104, Pregabalin (controlled-release, oral), Pfizer, (3S)-3-(aminomethyl)-5-methyl hexanoic acid, (S)-(+)-3-Aminomethyl-5-Methylhexanoic Acid, D02716, W-5218, AB01563007_01, 553P508, A808784, SR-01000942257, SR-01000942257-2, Pregabalin, EuropePharmacopoeia (EP) Reference Standard, Z2757554242, SCHEMBL17510367, CJ-00101, ZB000606

ID: 195

InChIKey: AYYIGRQBAFQJNP-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1)N=C(C(=C2)C#N)NCCNC(=O)C3=CC(=C(C=C3)OC)OC

biological descriptors:

CFTR relevance: CFTR Corrector and Potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"MJ Kurth" "PW Phuan" "AS Verkman" "AB Wood" "JM Knapp" "B Yang" "GL Lukacs"

CID is 3217032
synonyms found at PubChem are:
ASN 06146861, 606105-54-8, N-[2-(3-Cyano-6-methyl-quinolin-2-ylamino)-ethyl]-3,4-dimethoxy-benzamide, AC1MLAS4, MLS001212847, CHEMBL1403454, SCHEMBL14235628, CTK5B1874, DTXSID50390443, HMS2838E12, ZINC19221181, AKOS000765357, SMR000503709, KB-301135, SR-01000341403, SR-01000341403-1, N-[2-[(3-cyano-6-methylquinolin-2-yl)amino]ethyl]-3,4-dimeth, N-[2-[(3-cyano-6-methylquinolin-2-yl)amino]ethyl]-3,4-dimethoxybenzamide, N-{2-[(3-Cyano-6-methyl-2-quinolinyl)amino]ethyl}-3,4-dimethoxybenzamide, BENZAMIDE, N-[2-[(3-CYANO-6-METHYL-2-QUINOLINYL)AMINO]ETHYL]-3,4-DIMETHOXY-

ID: 196

InChIKey: AZJNIMLZMPQSPE-XFULWGLBSA-N
SMILES: CCCN1CCC[C@H](C1)C2=CC=CC(=C2)C#N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957534
synonyms found at PubChem are:
S(-)-DS 121 hydrochloride, EU-0100449, S(-)-Ds 121 HCl, CHEMBL1255935, CTK8G3010, S(-)-DS 121 hydrochloride, solid, NCGC00093865-01, D-206, SR-01000076231, SR-01000076231-1, S(-)-3-(1-Propyl-3-piperidinyl)-benzonitrile hydrochloride, S(-)-3-(1-Propyl-3-piperidinyl)benzonitrile hydrochloride-hemicarbonate salt

ID: 197

InChIKey: AZQWKYJCGOJGHM-UHFFFAOYSA-N
SMILES: C1=CC(=O)C=CC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4650
synonyms found at PubChem are:
p-benzoquinone, Benzoquinone, 1,4-BENZOQUINONE, Quinone, 106-51-4, p-Quinone, Chinone, 2,5-Cyclohexadiene-1,4-dione, para-Benzoquinone, Cyclohexadienedione, para-Quinone, 1,4-Benzoquine, cyclohexa-2,5-diene-1,4-dione, 1,4-Dioxybenzene, Steara pbq, p-Chinon, 1,4-Cyclohexadienedione, Benzo-chinon, Benzo-1,4-quinone, 1,4-Diossibenzene, 1,4-Dioxy-benzol, 1,4-Cyclohexadiene dioxide, Semiquinone anion, semiquinone radicals, RCRA waste number U197, NCI-C55845, p-Chinon [German], Benzo-chinon [German], Caswell No. 719C, USAF P-220, Chinon [Dutch, German], Cyclohexadiene-1,4-dione, 1,4-Benzochinon, NSC 36324, 1,4-Dioxy-benzol [German], CCRIS 933, 1,4-Diossibenzene [Italian], UNII-3T006GV98U, [1,4]benzoquinone, CHEBI:16509, HSDB 1111, Quinone1,4-Benzoquinone, EINECS 203-405-2, UN2587, RCRA waste no. U197, EPA Pesticide Chemical Code 059805, CHEMBL8320, AI3-09068, AZQWKYJCGOJGHM-UHFFFAOYSA-N, 3T006GV98U, DSSTox_CID_145, DSSTox_RID_75398, DSSTox_GSID_20145, CAS-106-51-4, p-benzo-quinone, 1,4 benzoquinone, Quinone; p-BQ, NSC36324, NSC-36324, 2,4-dione, p-BQ, PubChem14592, ACMC-1BVRL, Benzo-1,4-quinone #, (p-Phenylenedioxy)radical, Lopac-B-1266, Benzoquinone [UN2587], D0M2EM, Epitope ID:116219, WLN: L6V DVJ, Chinon(DUTCH, GERMAN), EC 203-405-2, AC1L1IN7, cid_4650, Lopac0_000120, SCHEMBL18103, Benzil-related compound, 53, KSC175I8T, MLS002454445, GTPL6307, 2,5-cyclohexadiene-1-4-dione, Jsp000586, DTXSID6020145, p-Benzoquinone, 98% 250g, BDBM22774, CTK0H5489, MolPort-001-760-607, HMS2230N13, HMS3260G22, ZINC895247, Benzoquinone [UN2587] [Poison], Tox21_202020, Tox21_302970, Tox21_500120, ANW-15407, BBL010327, Benzoquinone [UN2587] [Poison], c0261, LS-403, MFCD00001591, SBB058657, STK398389, AKOS000119965, AKOS025243267, CCG-204215, LP00120, LS41078, MCULE-2576853438, RP18884, RTR-033960, TRA0174019, UN 2587, p-Benzoquinone, reagent grade, >=98%, NCGC00015139-01, NCGC00015139-02, NCGC00015139-03, NCGC00015139-04, NCGC00015139-05, NCGC00015139-06, NCGC00015139-07, NCGC00091053-01, NCGC00091053-02, NCGC00091053-03, NCGC00256505-01, NCGC00259569-01, NCGC00260805-01, AN-22439, BC250046, KB-10508, SC-19123, SMR000326659, AB1002099, KB-204417, ST2412641, TR-033960, B0089, B0887, EU-0100120, ST51036952, 6402-EP2270505A1, 6402-EP2305689A1, 6402-EP2309584A1, 6402-EP2315303A1, 6402-EP2371812A1, B 1266, C00472, M-7408, 73907-EP2275469A1, 73907-EP2277862A2, 73907-EP2287940A1, 73907-EP2289965A1, 73907-EP2295416A2, 73907-EP2298748A2, 73907-EP2298770A1, 73907-EP2298828A1, 73907-EP2305808A1, 73907-EP2308926A1, 73907-EP2309564A1, 73907-EP2380568A1, 84801-EP2277862A2, 84801-EP2305808A1, 2,5-Cyclohexadiene-1,4-dione, radical ion(1-), 205985-EP2371803A1, 205985-EP2377843A1, A801452, SR-01000075705, I01-0464, J-503966, SR-01000075705-1, F1908-0067, InChI=1/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4, UNII-3X2WQ5ZIW6 component AZQWKYJCGOJGHM-UHFFFAOYSA-N, 1,4-Benzoquinone, pharmaceutical secondary standard; traceable to USP, 1,4-Benzoquinone, United States Pharmacopeia (USP) Reference Standard, p-Benzoquinone, for spectrophotometric det. of amines, >=99.5% (HPLC), 1,4-Benzoquinone, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 198

InChIKey: BAFKRPOFIYPKBQ-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1OC2=C(C=C(C=N2)Cl)Cl)OC3=C(C=C(C=N3)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5382
synonyms found at PubChem are:
tcpobop, 76150-91-9, 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, 1,4-BDPOB, CCRIS 3521, 1,4-Bis(2-(3,5-dichloropyridyloxy))benzene, 2,2'-[1,4-phenylenebis(oxy)]bis(3,5-dichloropyridine), MLS000532100, 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene, 3,5-DICHLORO-2-{4-[(3,5-DICHLOROPYRIDIN-2-YL)OXY]PHENOXY}PYRIDINE, IN1064, 2,2'-(1,4-Phenylenebis(oxy))bis(3,5-dichloropyridine), Pyridine,2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro-, 2,2'-[benzene-1,4-diylbis(oxy)]bis(3,5-dichloropyridine), SMR000137041, 3,5-dichloro-2-[4-(3,5-dichloropyridin-2-yl)oxyphenoxy]pyridine, DSSTox_CID_175, DSSTox_RID_75417, DSSTox_GSID_20175, Pyridine, 2,2'-(1,4-phenylenebis(oxy))bis(3,5-dichloro-, TCD, CAS-76150-91-9, 1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene, 1,4-bis[(3,5-dichloropyridin-2-yl)oxy]benzene, SR-01000076146, PYRIDINE, 2,2'-[1,4-PHENYLENEBIS(OXY)]BIS[3,5-DICHLORO-, Spectrum5_002035, Lopac-T-1443, D02BPI, AC1L1K8B, AC1Q3KP4, AC1Q3S6R, cid_5382, BIDD:PXR0116, Lopac0_001174, SCHEMBL240269, CHEMBL488803, GTPL2756, DTXSID8020175, BDBM89873, CTK5E2523, MolPort-000-659-900, HMS2488C03, HMS3263L09, ZINC1751810, Tox21_200168, Tox21_302870, Tox21_501174, IN2330, MFCD00057368, STK018912, AKOS001026934, CCG-205248, LP01174, MCULE-6622369223, TCPOBOP, >=98% (HPLC), solid, NCGC00016001-01, NCGC00016001-02, NCGC00016001-03, NCGC00016001-04, NCGC00016001-05, NCGC00016001-06, NCGC00016001-07, NCGC00094431-01, NCGC00094431-02, NCGC00094431-03, NCGC00094431-04, NCGC00256438-01, NCGC00257722-01, NCGC00261859-01, CJ-29650, KB-60701, LS-131890, B6644, EU-0101174, FT-0715320, 1,4-bis(3,5-dichloropyridin-2-yloxy)benzene, KS-00001850, 1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene, T 1443, C-44342, 3,3',5,5'-Tetrachloro-1,4-bis(pyridyloxy)benzene, SR-01000076146-1, SR-01000076146-5, Z56756152, F3284-1261, 3,5-dichloro-2-[4-[(3,5-dichloro-2-pyridinyl)oxy]phenoxy]pyridine, 3,5-dichloro-2-[4-[(3,5-dichloro-2-pyridyl)oxy]phenoxy]pyridine, 2-[4-[3,5-bis(chloranyl)pyridin-2-yl]oxyphenoxy]-3,5-bis(chloranyl)pyridine, 3,3 inverted exclamation marka,5,5 inverted exclamation marka-Tetrachloro-1,4-bis(pyridyloxy)benzene, 99916-31-1

ID: 199

InChIKey: BAINIUMDFURPJM-UHFFFAOYSA-N
SMILES: C1CN(CCN1CCCN2C3=CC=CC=C3NC2=O)C(C4=CC=CC=C4)C5=CC=CC=C5

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4615
synonyms found at PubChem are:
oxatomide, 60607-34-3, Tinset, Oxatimide, Oxatomida, Celtect, Oxetal, Oxatomidum, KW-4354, Oxatomidum [INN-Latin], Oxatomida [INN-Spanish], McN-JR 35443, R 35443, 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one, UNII-J31IL9Z2EE, 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one, 1-(3-(4-Benzhydrylpiperazin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, Oxatomide (tinset), Celtect (TN), C27H30N4O, Oxatomide [USAN:BAN:INN:JAN], EINECS 262-320-9, CBMicro_024634, R-35443, KW 4354, BRN 4724760, J31IL9Z2EE, Oxatomide (JAN/USAN/INN), 1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one, MLS000028549, BAINIUMDFURPJM-UHFFFAOYSA-N, R35443, 1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-2-benzimidazolinone, R 35,443, NCGC00015774-03, SMR000058301, 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-2-benzimidazolinone, 1-[3-(4-Benzhydryl-piperazin-1-yl)-propyl]-1,3-dihydro-benzoimidazol-2-one, O 9387, DSSTox_CID_25181, DSSTox_RID_80729, DSSTox_GSID_45181, W-105243, 3-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1H-benzimidazol-2-one, 3-[3-[4-(diphenylmethyl)piperazin-1-yl]propyl]-1H-benzimidazol-2-one, 2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-, 2H-Benzimidazol-2-one, 1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-, CAS-60607-34-3, celtomide, Cobiona, Dasten, 1-{3-[4-(diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one, Oxatomide [USAN:INN:BAN:JAN], Oxatomide, >=99%, AC1L1IKA, Lopac-O-9387, D0AJ5L, cid_4615, Lopac0_000924, Oprea1_338592, REGID_for_CID_4615, SCHEMBL28824, CHEMBL13828, DTXSID4045181, BDBM76863, CHEBI:31943, CTK7H0209, MolPort-001-964-500, HMS2089N07, HMS2231H12, HMS3372K08, Tox21_110219, CCG-11811, MFCD00211147, NSC309710, ZINC19632896, AKOS000507212, Tox21_110219_1, AB04841, API0024517, DB12877, KS-1375, NSC-309710, VA11458, NCGC00015774-01, NCGC00015774-02, NCGC00015774-04, NCGC00015774-05, NCGC00015774-06, NCGC00094235-01, NCGC00094235-02, AJ-74101, AN-39436, BAS 01509783, LS-33365, SC-17011, BIM-0024581.P001, AX8146443, KB-213408, EU-0100924, FT-0630723, ST50253168, D01773, 54331-EP2308562A2, 54331-EP2371811A2, AB01227629-02, 607O343, A832804, SR-01000076051, I06-0696, R 35 443, SR-01000076051-1, 1-[3-[4-(DIPHENYLMETHYL)-1-PIPERAZINYL]PROPYL]-1,3, 3-[3-(4-benzhydrylpiperazino)propyl]-1H-benzimidazol-2-one, 1-{3-[4-(diphenylmethyl)piperazinyl]propyl}-3-hydrobenzimidazol-2-one, 1-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one, 1-{3-[4-(diphenylmethyl)-1-piperazinyl}-propyl}-1,3-dihydro-2H-benzimidazol-2-one, 1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2h-benzimidazol-2-one, 1{-[4-(diphenylmethyl)-1-piperzinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one, AC1LQZR1, MolPort-000-714-823, STL046521, AKOS005699997, MCULE-7893533906, 1-[3-(4-benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate, 1-{3-[4-(diphenylmethyl)piperazin-1-ium-1-yl]propyl}-1H-benzimidazol-2-olate

ID: 200

InChIKey: BATPBOZTBNNDLN-PFEQFJNWSA-N
SMILES: CCCN(CCC)[C@@H]1CCC2=C(C1)C(=CC=C2)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957570
synonyms found at PubChem are:
(R)-(+)-8-Hydroxy-DPAT hydrobromide, 78095-19-9, UNII-0S6YNT39TH, R-(+)-8-Hydroxy-DPAT hydrobromide, 0S6YNT39TH, R(+)-8-Hydroxy DPAT HBr, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide, (R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (+)8-OH-DPAT hydrobromide, C16H25NO.HBr, MLS001056795, CHEMBL541268, SCHEMBL1682308, CTK8F2010, AOB5358, DTXSID20474688, MolPort-003-941-603, Tox21_500638, BN0042, MFCD00153810, 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide, (R), AKOS015966328, CCG-221942, LP00638, NCGC00094005-01, NCGC00261323-01, AS-16873, SMR000326964, LS-177397, B6588, EU-0100638, H-140, SR-01000075925, SR-01000597921, SR-01000075925-1, SR-01000597921-1, (+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide, UNII-G8TFV2F5CP component BATPBOZTBNNDLN-PFEQFJNWSA-N, (2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (R)-(+)-8-Hydroxy-DPAT hydrobromide, >=98% (HPLC), solid, r-(+)-8-hydroxy-2-(di-n-propylamino) tetralin hydrobromide, 8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (R)-Isomer,, (R)-7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide

ID: 201

InChIKey: BATPBOZTBNNDLN-WIROKCJUSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])N(CCC)C1CCC2=C(C1)C(=CC=C2)O.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71748987
synonyms found at PubChem are:
8-OH DPAT-d7, BATPBOZTBNNDLN-WIROKCJUSA-N, rac-8-Hydroxy-2-dipropylaminotetralin-d7 Hydrobromide, (+/-)-8-Hydroxy(N,N-dipropyl-2-amino)tetralin-d7 Hydrobromide, 7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol-d7 Hydrobromide, 1329613-23-1

ID: 202

InChIKey: BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C4N=CN=C5N)O)O)O)O)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5892
synonyms found at PubChem are:
nadide, NAD+, coenzyme I, 53-84-9, beta-NAD, beta-NAD+, diphosphopyridine nucleotide, beta-Diphosphopyridine nucleotide, Enzopride, nicotinamide adenine dinucleotide, Codehydrase I, beta-nicotinamide adenine dinucleotide, Cozymase I, Codehydrogenase I, CO-1, CO-I, NAD, Nadidum [INN-Latin], Nadida [INN-Spanish], beta-DPN, Pyridine, nucleotide diphosphate, Nicotinamide-adenine dinucleotide, NAD zwitterion, COZYMASE, Nicotinamide dinucleotide, Adenine-nicotinamide dinucleotide, NAD+, Free Acid, Nadide [USAN:INN:BAN:JAN], Oxidized diphosphopyridine nucleotide, EINECS 200-184-4, NSC 20272, BRN 3584133, CHEBI:44215, BAWFJGJZGIEFAR-NNYOXOHSSA-N, C21H27N7O14P2, UNII-0U46U6E8UK, MFCD00036253, 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt, Nicotinamide-Adenine-Dinucleotide, DPN-ox, Adenosine 5'-(trihydrogen diphosphate), P'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt, Adenosine 5'-(trihydrogen diphosphate), P'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt, nicotinamide adenine dinucleotide oxidized, DPN+, Nadidum, Nadida, 0U46U6E8UK, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate, Adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, hydroxide, inner salt, Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5'-ester with adenosine 5'-5'-(trihydrogen pyrophosphate), inner salt, diphosphopyridine nucleotide oxidized, beta-Nicotinamide adenine dinucleotide hydrate, NSC20272, CAS-53-84-9, Cozymasei(NAD+), NCGC00016240-01, b-NAD, oxidised form, C-NAD, beta-NAD, oxidised form, 3-carbamoylpyridin-1-ium, Carbonyl [14C] NAD+, D0M3KZ, EC 200-184-4, AC1L1LD0, NAD, Grade I, free acid, [adenylate-32-P]-NAD+, DSSTox_CID_25236, DSSTox_RID_80768, NAD, Grade II, free acid, DSSTox_GSID_45236, 5-26-16-00399 (Beilstein Handbook Reference), SCHEMBL131544, SPECTRUM1500419, beta-Diphosphopyridinenucleotide, GTPL2451, CHEMBL1234613, DTXSID2045236, CTK8B3792, HMS500J11, Nicotinamide Adinine Dinucleotide, MolPort-003-666-238, [14C] NAD+, [32P] NAD+, b-Nicotinamide adenine dinucleotide, BDBM213227, HMS2091H06, HMS2097E04, HMS3714E04, Pharmakon1600-01500419, HY-B0445, Diphosphopyridine nucleotide (DPN+), Tox21_110321, 6614AF, ANW-43201, CCG-40114, NSC757121, s2518, AKOS015892319, beta-nicotinamide adenine din-ucleotide, CM11026, CS-2554, NSC-757121, .beta.-Nicotinamide adenine dinucleotide, Nicotinamide adenine dinucleotide (NAD), NCGC00178839-01, NCGC00178839-02, AS-14652, M041, SBI-0051451.P003, AB2000620, LS-132322, TR-019029, AB00513910, D0919, beta-Nicotinamide adenine dinucleotide, reduced, N-2550, AB00052048_03, b-Nicotinamide adenine dinucleotide hydrate (NAD), I02-6267, Nicotinamide adenine dinucleotideNAD+mono sodium salt, beta-Nicotinamide adenine dinucleotide hydrate, >=99%, F45C0D6C-DA87-47BE-9975-7A5DE9CCB985, beta-Nicotinamide adenine dinucleotide hydrate, >=95% (HPLC), beta-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial), beta-Nicotinamide adenine dinucleotide, pkg of 20 mg (per vial), beta-Nicotinamide adenine dinucleotide, pkg of 50 mg (per vial), beta-Nicotinamide adenine dinucleotide hydrate, >=98%, BioUltra, from yeast, beta-Nicotinamide adenine dinucleotide hydrate, Grade AA-1, >=95% (HPLC), beta-Nicotinamide adenine dinucleotide hydrate, purified by column chromatography, >=99%, beta-Nicotinamide adenine dinucleotide hydrate, Vetec(TM) reagent grade, >=96.5%, [(3S,2R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl {[(3S,2R,4R,5R)-5-(3-carbamoylpyridyl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxyphosphoryl)hydrogen phosphate, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate, 1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-, 1083039-67-1, 1354693-98-3, 159929-29-0, 30429-30-2, Adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt, Adenosine 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt, Adenosine 5'-(trihydrogen diphosphate-P-32P), P'>5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt (9CI), adenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] hydrogen diphosphate}, beta-Nicotinamide adenine dinucleotide hydrate, >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast, beta-Nicotinamide adenine dinucleotide hydrate, cell culture tested, >=96.5% (HPLC), >=96.5% (spectrophotometric assay), from yeast, beta-Nicotinamide adenine dinucleotide hydrate, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., beta-Nicotinamide adenine dinucleotide hydrate, Suitable for manufacturing of diagnostic kits and reagents, Pyridinium, 3-carbamoyl-1-b-D-ribofuranosyl-, hydroxide, 5'-5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt (8CI), AC1NRCGS, D0R6JE, [[(2R,3S,4R,5R)-5-(6-amino-7H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

ID: 203

InChIKey: BBAZDLONIUABKI-UHFFFAOYSA-N
SMILES: CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 28767
synonyms found at PubChem are:
CLORGYLINE HYDROCHLORIDE, 17780-75-5, CLORGILINE HYDROCHLORIDE, Clorgyline HCl, Clorgiline (hydrochloride), N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, UNII-H38V165133, EINECS 241-760-5, MLS000028750, NCGC00094088-01, SMR000058474, H38V165133, DSSTox_CID_25778, DSSTox_RID_81120, DSSTox_GSID_45778, N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)-propylamine hydrochloride, 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine hydrochloride, N-(3-(2,4-Dichlorophenoxy)propyl)-N-methyl-2-propynylamine hydrochloride, N-(3-(2,4-dichlorophenoxy)propyl)-N-methylprop-2-yn-1-amine hydrochloride, Propylamine, 3-(2,4-dichlorophenoxy)-N-methyl-N-propargyl-, hydrochloride, 2-Propynylamine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride (7CI,8CI), Prestwick_762, 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride, SR-01000075629, C13H15Cl2NO.ClH, CAS-17780-75-5, 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine;hydrochloride, Opera_ID_713, AC1L1G0Y, MLS001076555, MLS002222259, SCHEMBL467295, CHEMBL539507, DTXSID3045778, CTK8F8739, KS-00000THU, MolPort-003-958-719, HMS1569E09, Pharmakon1600-01506065, Tox21_111243, Tox21_500746, 2330AH, BN0795, HY-14197A, IN2369, MFCD00052012, NSC759306, AKOS027257188, Tox21_111243_1, CCG-213696, CS-4553, LP00746, NSC-759306, QC-1478, NCGC00015669-07, NCGC00094088-02, NCGC00180962-01, NCGC00261431-01, AK209997, KB-79506, SC-89481, 17780-75-5 (HCl), LS-125601, EU-0100746, A20772, F10028, M 3778, J-011321, SR-01000075629-1, SR-01000075629-5, SR-01000075629-6, N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)-propylamine, 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride (9CI), 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynyl-propan-1-amine hydrochloride, N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, >=97% (GC), AKOS026750027

ID: 204

InChIKey: BBFQZRXNYIEMAW-UHFFFAOYSA-N
SMILES: COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2236
synonyms found at PubChem are:
Aristolochic acid, Aristolochic acid A, Aristolochic acid I, 313-67-7, Aristolochin, Tardolyt, Birthwort, Aristolochic acid-I, ARISTOLOCHINE, TR 1736, Aristolochiazaeure, C17H11NO7, NSC11926, NSC-50413, UNII-94218WFP5T, CCRIS 1544, NSC50413, EINECS 206-238-3, NSC 11926, NSC 50413, 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid, 8-Methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid, BRN 0345159, CHEMBL93353, MLS002702976, CHEBI:2825, 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid, 94218WFP5T, 8-Methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure, 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid, Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, Q-100394, 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid, 8-Methoxy-6-Nitrophenanthol-(3,4-d)-1,3-Dioxole-5-Carboxylic Acid, 8-METHOXY-6-NITROPHENANTHROL(3,4-D)-1,3-DIOXIDE-5-CARBOXYLIC ACID, SMR001562128, Aristolochic acid 1, SR-05000002369, Aristolochid, Aristolochind, Descresepd, Tardolyd, Phenanthro[3,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, Aristinic acid, aris-tolochic acid, Aristolochia yellod, Aristolochic-acid-A, Spectrum_001156, SpecPlus_000448, Spectrum2_000822, Spectrum3_001114, Spectrum4_001952, Spectrum5_000729, Aristolochic acid A,(S), ZINC52, NCIMech_000812, Aristolochic acid I, powder, BSPBio_001440, BSPBio_002848, KBioGR_000160, KBioGR_002387, KBioSS_000160, KBioSS_001636, MLS002695974, DivK1c_006544, SCHEMBL166284, SPECTRUM1502233, SPBio_000743, AC1L1D86, DTXSID0040969, CTK4G6973, HSDB 7179, KBio1_001488, KBio2_000160, KBio2_001636, KBio2_002728, KBio2_004204, KBio2_005296, KBio2_006772, KBio3_000319, KBio3_000320, KBio3_002068, BBFQZRXNYIEMAW-UHFFFAOYSA-N, MolPort-001-797-985, Bio1_000418, Bio1_000907, Bio1_001396, Bio2_000160, Bio2_000640, HMS1361H22, HMS1791H22, HMS1989H22, HMS3402H22, TNP00273, 8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, AN-319, BDBM50306855, CCG-35796, CCG-36162, MFCD00004996, NSC-11926, AKOS015896751, API0000398, MCULE-3861334509, IDI1_033910, NCGC00017334-01, NCGC00017334-02, NCGC00017334-03, NCGC00017334-04, NCGC00017334-05, NCGC00017334-06, NCGC00017334-07, NCGC00095981-01, NCGC00095981-02, NCGC00095981-03, NCGC00095981-04, NCGC00095981-05, CC-24181, LS-21656, NCI60_000460, SC-14173, ST057179, AB0028965, TR-013344, FT-0602867, N2032, ST50307164, X1086, C08469, 313A677, C-20352, I07-0211, SR-05000002369-2, SR-05000002369-3, A000071790, 8-METHOXY-6-NITROPHENANTHROL(3,4-D)-1,3-DIOXIDE-5-, Aristolochia, European Pharmacopoeia (EP) Reference Standard, 8-Methoxy-6-nitro-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid, 8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid, Aristolochic acid I, European Pharmacopoeia (EP) Reference Standard, 8-methoxy-6-nitro-2H-phenanthro[3,4-d]1,3-dioxolene-5-carboxylic acid, 8-methoxy-6-nitro-2H-phenanthro[4,3-d]1,3-dioxolene-5-carboxylic acid, 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid #, Phenanthro[3,4-d]-1,3-dioxole-5-carbocylic acid, 8-methoxy-6-nitro-, 12770-90-0, 61117-05-3

ID: 205

InChIKey: BBNQQADTFFCFGB-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6683
synonyms found at PubChem are:
PURPURIN, 81-54-9, 1,2,4-Trihydroxyanthraquinone, Purpurine, Verantin, Hydroxylizaric acid, Smoke Brown G, 1,2,4-trihydroxyanthracene-9,10-dione, 1,2,4-Trihydroxy-9,10-anthracenedione, 1,2,4-Trihydroxy-9,10-anthraquinone, 1,2,4-Trihydroxyanthrachinon, C.I. 58205, 9,10-Anthracenedione, 1,2,4-trihydroxy-, 1,2,4-Trihydroxyanthra-9,10-quinone, Anthraquinone, 1,2,4-trihydroxy-, UNII-L1GT81LS6N, C.I. 75410, CCRIS 3527, CHEBI:8645, C.I. 1037, EINECS 201-359-8, NSC 10447, 1,2,4-Trihydroxyanthrachinon [Czech], BRN 1887127, L1GT81LS6N, MLS002473304, Purpurin (C.I. 58205), 1,2,4-Trihydroxy-Anthraquinone, BBNQQADTFFCFGB-UHFFFAOYSA-N, NSC10447, SMR001306802, purpurin, madder root, Alizarin purpurin, Purpurin(e), 4-Hydroxyalizarin, C.I. Natural Red 8, Spectrum2_000037, Spectrum3_001947, C.I. Natural Red 16, DSSTox_CID_1214, 1,4-Trihydroxyanthrachinon, D0XJ7I, Epitope ID:116185, NCIMech_000036, 1,4-Trihydroxyanthraquinone, AC1L1N2S, cid_6683, 9, 1,2,4-trihydroxy-, DSSTox_RID_76013, DSSTox_GSID_21214, SCHEMBL33871, BSPBio_003547, 4-08-00-03568 (Beilstein Handbook Reference), hsp90_173, MLS002207287, SPECTRUM1505300, Purpurin, Dye content 90 %, SPBio_000133, Anthraquinone,2,4-trihydroxy-, CHEMBL294264, DTXSID4021214, BDBM67454, CTK8B4080, KBio3_002835, MolPort-000-627-704, HMS2232F04, HMS3374D11, ZINC3861633, ZX-AT016169, Tox21_301526, 1,4-Trihydroxy-9,10-anthraquinone, 6256AF, ANW-43819, BBL027328, CCG-35463, GT4917, MFCD00001203, NSC-10447, SBB006444, STK396669, AKOS001482720, 4,9,10-trihydroxy-1,2-anthraquinone, API0003984, MCULE-4728464964, SDCCGMLS-0066870.P001, CAS-81-54-9, KS-0000128Y, NCGC00095346-01, NCGC00095346-02, NCGC00095346-03, NCGC00255399-01, WLN: L C666 BV IVJ DQ EQ GQ, AK405332, LS-20715, NCI60_000107, ST055354, 1,2,4-Trihydroxyanthra-9,10-quinone #, TR-025626, 1,2,4-tris(oxidanyl)anthracene-9,10-dione, EU-0000318, FT-0699020, P0605, A-8888, C10395, Purpurin, for spectrophotometric det. (of B, Pb), SR-05000002508, 9,10-Anthracenedione, 1,2,4-trihydroxy- (9CI), Purpurin - CASMI2016 Category 1 - Challenge 18, SR-05000002508-1, I14-46575, InChI=1/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19

ID: 206

InChIKey: BBQATSUGRGRBBM-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC(=O)C4=C(O3)C=CC=C4O

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 73350462
synonyms found at PubChem are:
CHEMBL2386398

ID: 207

InChIKey: BBSPXZBAZKHYLF-HUBYRZTESA-N
SMILES: C[C@@]12CCC3[C@]4([C@H](C[C@H](C(C4CC(=O)[C@]3(C15C(O5)C(=O)O[C@H]2C6=COC=C6)C)(C)C)O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708618
synonyms found at PubChem are:
1,3-DIDEACETYL-7-DEACETOXY-7-OXOKHIVORIN, KBio2_000916, Spectrum_000436, SpecPlus_000247, Spectrum2_000280, Spectrum3_000074, Spectrum4_001566, Spectrum5_000192, BSPBio_001887, KBioGR_002092, KBioSS_000916, SPECTRUM100355, DivK1c_006343, SPBio_000160, SCHEMBL10019483, KBio1_001287, KBio2_003484, KBio2_006052, KBio3_001107, CCG-39838, SDCCGMLS-0066291.P001, NCGC00178926-01, SR-05000002688, SR-05000002688-1, BRD-A34891365-001-02-4, BRD-A34891365-001-03-2

ID: 208

InChIKey: BCLBHEQMAQXMBH-UHFFFAOYSA-N
SMILES: CC(C)(CCP(=O)(O)O)C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957608
synonyms found at PubChem are:
(S)-MAP4 hydrochloride, EU-0100768, CHEMBL1453308, Tox21_500768, CCG-222072, LP00768, NCGC00094107-01, NCGC00261453-01, M 5560, SR-01000075302, SR-01000075302-1, (S)-2-Amino-2-methyl-4-phosphonobutanoate hydrochloride

ID: 209

InChIKey: BCVIWCRZYPHHMQ-BTJKTKAUSA-N
SMILES: COC1=CC(=C(C=C1C(=O)NC2CCN(CC2)CC3=CC=CC=C3)Cl)N.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6420010
synonyms found at PubChem are:
Clebopride maleate, Clebopride maleate salt, 84370-95-6, UNII-P42041X5SU, P42041X5SU, DSSTox_CID_27767, DSSTox_RID_82544, DSSTox_GSID_47787, SR-05000001882, NCGC00016951-01, CAS-84370-95-6, 4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine, Prestwick_758, AC1O4WHU, SPECTRUM1503991, SCHEMBL2323725, CHEMBL1599248, DTXSID6047787, HMS1569K21, HMS1922O18, HMS2096K21, HMS3713K21, C20H24ClN3O2.C4H4O4, Tox21_110706, CCG-39007, MFCD00079080, AKOS027380882, Tox21_110706_1, NCGC00016951-05, NCGC00095091-01, NCGC00095091-02, X4636, SR-05000001882-1, SR-05000001882-2, 4-[4-Amino-5-chloro-2-methoxybenzamido]-1-benzylpiperidine maleate salt, 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide; (Z)-but-2-enedioic acid

ID: 210

InChIKey: BCXCABRDBBWWGY-UHFFFAOYSA-N
SMILES: CN(CC#C)CC1=CC=CC=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9373
synonyms found at PubChem are:
Pargyline hydrochloride, 306-07-0, Pargyline HCl, Eutonyl-ten, N-benzyl-N-methylprop-2-yn-1-amine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride, N-Methyl-N-2-propynylbenzylamine hydrochloride, Pargyline chloride, Pargyline (hydrochloride), USAF A-19120, UNII-W70V6I2OMY, Benzylmethylpropynylamine hydrochloride, Methylbenzylpropynylamine hydrochloride, EINECS 206-175-1, MO-911, N-Benzyl-N-methyl-2-propynylamine hydrochloride, NSC 43798, W70V6I2OMY, AI3-62178, MLS000028460, Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride, Pargyline hydrochloride [USAN], N-Methyl-N-(2-propynyl)benzylamine hydrochloride, A-19120, 2-Propynylamine, N-benzyl-N-methyl-, hydrochloride, BENZYLAMINE, N-METHYL-N-2-PROPYNYL-, HYDROCHLORIDE, SMR000058367, DSSTox_CID_24647, DSSTox_RID_80375, DSSTox_GSID_44647, Pargyline hydrochloride (USAN), C11H13N, NSC43798, N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride, SR-01000003035, NCGC00015841-02, CAS-306-07-0, Pargyline, HCl, Prestwick_377, Eutonyl (TN), Pargyline hydrochloride [USAN:USP], Opera_ID_404, Pargylamine hydrochloride, AC1L1SWM, MLS001076511, Pargyline hydrochloride, 99%, SCHEMBL121111, 2-Propynylamine, hydrochloride, n-methyl-n-2-propynylbenzenemethanamine hydrochloride, AC1Q38P0, CHEMBL1200425, DTXSID1044647, AOB5794, BCXCABRDBBWWGY-UHFFFAOYSA-N, MolPort-003-666-254, HMS1568F07, Pharmakon1600-01500462, BCP21320, HY-A0091, KS-000009PS, N-Methyl-N-propargylbenzylamine HCl, Tox21_110241, Tox21_302678, Tox21_501022, ACM306070, CCG-40239, MFCD00012492, NSC-43798, NSC757264, AKOS015950558, methylbenzylprop-2-ynylamine, chloride, Tox21_110241_1, API0002665, LP01022, MCULE-9689491047, NSC-757264, TRA0075401, VA11492, WLN: 1UU2N1 & 1R & GH, NCGC00015841-11, NCGC00094313-01, NCGC00094313-02, NCGC00094313-03, NCGC00256654-01, NCGC00261707-01, AC-18917, AK139345, AS-16929, BC214776, LS-43404, SY005867, AB1000616, AX8146773, DB-047811, N-Methyl-N-propargylbenzylamineHydrochloride, TC-308744, EU-0101022, FT-0631924, ST24048517, ST51006955, V1637, BIM-0050995.0001, D02564, P 8013, Z-3950, A820454, C-49528, SR-01000003035-2, SR-01000003035-7, SR-01000003035-11, N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride, N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride, Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1), Benzenemethanamine,N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1);, Pargyline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 8055-70-7, N-Methyl-N-(2-propynyl)benzylamine hydrochloride; N-Methyl-N-propargylbenzylamine hydrochloride, AC1LCW5R, AKOS015901137, I14-15063, N-benzyl-N-methylprop-2-yn-1-amine; hydron; chloride

ID: 211

InChIKey: BCYMEDQAEFBAKK-NFXXEGMFSA-N
SMILES: C[C@H]1C2C(CC3C2([C@@H](C(=O)C4C3CCC5C4(CC[C@@H](C5)OC(=O)CCC(=O)OC)C)O)C)OC16CCC(CO6)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6710697
synonyms found at PubChem are:
Spectrum_001787, Spectrum2_001252, Spectrum5_001800, KBioSS_002275, SPBio_001184, KBio2_002274, KBio2_004842, KBio2_007410, CCG-39103, METHYL 3beta,12-DIHYDROXY-11-KETOISOALLOSPIROSTAN-3-HEMISUCCINATE

ID: 212

InChIKey: BDJRBEYXGGNYIS-UHFFFAOYSA-N
SMILES: C(CCCC(=O)O)CCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2266
synonyms found at PubChem are:
azelaic acid, NONANEDIOIC ACID, 123-99-9, Finacea, Anchoic acid, Azelex, Lepargylic acid, Skinoren, 1,7-Heptanedicarboxylic acid, Heptanedicarboxylic acid, 1,9-Nonanedioic acid, Emerox 1110, Emerox 1144, n-Nonanedioic acid, acide azelaique, Finevin, Acido azelaico, Azelainic acid, acidum azelaicum, Polyazelaic anhydride, Skinorem, Azalaic Acid, Azelaic acid, technical grade, Emery's L-110, Acide azelaique [French], Acido azelaico [Spanish], Acidum azelaicum [Latin], Azelaic acid [USAN:INN], Azelaic polyanhydride, 1,7-Dicarboxyheptane, Azelaic, Azleaic Acid, Azelaic acid polyanhydride, ZK-62498, UNII-F2VW3D43YT, NSC 19493, Nonanedioic acid, homopolymer, Finacea (TN), Azelaic acid 99%, Azelex (TN), ZK 62498, CHEBI:48131, Poly(azelaic anhydride), EINECS 204-669-1, Azelaic acid (USAN/INN), BRN 1101094, F2VW3D43YT, AZELAIC ACID, 95%, AI3-06299, MLS000069659, BDJRBEYXGGNYIS-UHFFFAOYSA-N, azelaate, azelate, NSC19493, SH-441, AGN-191861, NCGC00014993-07, SMR000059164, DSSTox_CID_1640, A-9800, DSSTox_RID_76254, DSSTox_GSID_21640, 26776-28-3, AZ1, 123-99-9 (Parent), CAS-123-99-9, SR-01000075671, 27825-99-6, azelaicacid, Azelaicacidtech, Azelainsaeure, Azelainsaure, Lepargylate, Nonandisaeure, Nonandisaure, Anchoate, Nonanedioic acid, sodium salt, n-Nonanedioate, Acidum acelaicum, HSDB 7659, 1tuf, 1,9-Nonanedioate, Skinoren (TN), Finevin (TN), Dicarboxylic acid C9, Azelaic acid, 98%, Spectrum_000057, ACMC-1BTAP, Opera_ID_740, Polyazelaic Polyanhydride, AC1L1DAO, 1,7-Heptanedicarboxylate, Spectrum2_000995, Spectrum3_000278, Spectrum4_000401, Spectrum5_001304, D0E4WR, Epitope ID:187039, EC 204-669-1, Nonanedioic acid homopolymer, AC1Q75FC, Lopac-246379, SCHEMBL3887, Azelaic acid,technical grade, CHEMBL1238, azelaic acid dipotassium salt, Lopac0_000051, BSPBio_001756, KBioGR_000662, KBioSS_000437, Nonanedioic acid Azelaic acid, 4-02-00-02055 (Beilstein Handbook Reference), Azelaic acid, 98% 25g, KSC178S1P, MLS001148615, ARONIS24596, BIDD:GT0315, DivK1c_000532, SPECTRUM1500648, heptane-1,7-dicarboxylic acid, SPBio_001089, GTPL7484, DTXSID8021640, CTK0H8917, HMS501K14, KBio1_000532, KBio2_000437, KBio2_003005, KBio2_005573, KBio3_001256, KS-00000WLV, Azelaic acid, analytical standard, MolPort-001-779-873, NINDS_000532, HMS1921O11, HMS2092E22, HMS2234D10, HMS3260K03, HMS3372J07, Pharmakon1600-01500648, BCP18690, HY-B0704, KS-000046KE, ZINC1531036, Tox21_110063, Tox21_201989, Tox21_303011, Tox21_500051, ANW-18182, Azelaic acid, technical grade, 80%, CCG-40081, LMFA01170054, MFCD00004432, NSC-19493, NSC757406, s4550, SBB060279, STL059432, 38900-29-7 (di-lithium salt), 52457-54-2 (di-potassium salt), AKOS000120052, Tox21_110063_1, Azelaic acid, technical, ~85% (GC), Azelaic acid, Vetec(TM) reagent grade, DB00548, KS-5293, LP00051, LS41867, MCULE-4093240509, NE10317, NSC-757406, RP17465, RTR-003741, SDCCGMLS-0066619.P001, TRA0060478, IDI1_000532, MLS-0066619, 17265-13-3 (di-hydrochloride salt), NCGC00014993-01, NCGC00014993-02, NCGC00014993-03, NCGC00014993-04, NCGC00014993-05, NCGC00014993-06, NCGC00014993-08, NCGC00014993-09, NCGC00014993-10, NCGC00014993-12, NCGC00093565-01, NCGC00093565-02, NCGC00093565-03, NCGC00093565-04, NCGC00093565-05, NCGC00093565-06, NCGC00093565-07, NCGC00256508-01, NCGC00259538-01, NCGC00260736-01, 17356-30-8 (mono-hydrochloride salt), AN-22935, KB-74817, LS-22779, SC-16119, MLS-0066619.P021, SBI-0050040.P003, TR-003741, 19619-43-3 (unspecified potassium salt), A0561, Dicarboxylic acid C9; Nonanedioic acid; AZA, EU-0100051, FT-0626920, ST45053319, 27825-99-6 (unspecified hydrochloride salt), C08261, D03034, 21175-EP2269988A2, 21175-EP2270008A1, 21175-EP2275413A1, 21175-EP2287156A1, 21175-EP2292617A1, 21175-EP2301940A1, 21175-EP2314295A1, 21175-EP2374895A1, 21175-EP2380874A2, AB00052140_12, M112324, I04-0585, SR-01000075671-1, SR-01000075671-4, SR-01000075671-6, 0C50D8EC-0DB0-4F24-8EFC-2919E1F0D9BF, Z57127532, F8889-5093, 1219811-33-2, 32733-99-6, InChI=1/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13

ID: 213

InChIKey: BDYYDXJSHYEDGB-UHFFFAOYSA-N
SMILES: CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 19529
synonyms found at PubChem are:
DILOXANIDE FUROATE, 3736-81-0, Diloxanid furoate, Diclofurazol, Amebiazol, Furentomin, Entamide furoate, Dichlofurazol, Histomibal, Miforon, 4-(2,2-Dichloro-N-methylacetamido)phenyl furan-2-carboxylate, Entamide 2-furoate, Furamide (amebicide), Diloxanidefuroate, UNII-YP4N72IW34, MLS000028653, EINECS 223-108-1, Diloxanide furoate [USP], 8073 CB, SMR000058857, CHEBI:4601, YP4N72IW34, [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate, NCGC00016637-07, CAS-3736-81-0, 2-Furancarboxylic acid, 4-((dichloroacetyl)methylamino)phenyl ester, 2-Furoic acid, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide, Diloxanide furoate (USP), 4-((Dichloroacetyl)methylamino)phenyl 2-furoate, C13H9Cl2NO4, DSSTox_CID_28925, DSSTox_RID_83191, DSSTox_GSID_48999, 2,2-Dichloroacetamideo-4-N-methylphenyl 2-furoate, Q-200989, 4-(N-Methyl-2,2-dichloroacetamideo)phenyl 2-furoate, 2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide 2-furoic acid ester, 2,2-DICHLORO-N-[4-HYDROXYPHENYL]-N-METHYLACETAMIDE 2-FUROIC ACID ESTER, SR-01000003134, CB 8073, diloxanide furoate(usp), Diloxanide furoate (TN), Opera_ID_1633, Prestwick0_000903, Prestwick1_000903, Prestwick2_000903, Prestwick3_000903, AC1L2EB4, AC1Q61BK, SCHEMBL23381, BSPBio_000746, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat, cid_19529, MLS001148648, SPBio_002945, BPBio1_000822, ZINC1300, CHEMBL1334860, DTXSID8048999, BDBM70295, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat [IUPAC], HMS1570F08, HMS2093N21, HMS2097F08, HMS2234P06, HMS3371I07, HMS3714F08, Pharmakon1600-01505532, HY-B1147, Tox21_113492, 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat [IUPAC], MFCD00083302, NSC759146, AKOS016014036, Tox21_113492_1, API0002378, CCG-213477, CS-4751, NSC-759146, NCGC00016637-01, NCGC00016637-02, NCGC00016637-03, NCGC00016637-04, NCGC00016637-05, NCGC00016637-06, NCGC00016637-10, NCGC00023178-03, NCGC00023178-04, NCGC00023178-05, LS-70794, SBI-0206798.P001, AX8125210, KB-237263, AB00383052, FT-0752403, C07637, D02480, AB00383052_13, C-55187, SR-01000003134-2, SR-01000003134-4, BRD-K10974103-001-03-9, BRD-K10974103-001-14-6, 2,2-dichloro-4'-hydroxy-N-methylacetanilide 2-furoate, 4-(2,2-Dichloro-N-methylacetamido)phenylfuran-2-carboxylate, [4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] furan-2-carboxylate, [4-[2,2-bis(chloranyl)ethanoyl-methyl-amino]phenyl] furan-2-carboxylate, Diloxanide furoate, United States Pharmacopeia (USP) Reference Standard, 2-furancarboxylic acid [4-[(2,2-dichloro-1-oxoethyl)-methylamino]phenyl] ester, furan-2-carboxylic acid [4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] ester

ID: 214

InChIKey: BEEDODBODQVSIM-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66259
synonyms found at PubChem are:
Oxymetazoline hydrochloride, 2315-02-8, Oxymetazoline HCl, Afrazine, Ocuclear, Lliadine, Nasivin, Nasivine, Neonabel, Nostrilla, Operil, Afrin hydrochloride, Oxymetazoline (hydrochloride), Afrin, Nafrine hydrochloride, 4-Way Nasal Spray, Duration Nasal Spray, Oxymetazoline chloride, Vicks Sinex, LLiadin Mini Paediatric, Neo-Synephrine 12 Hour, UNII-K89MJ0S5VY, K89MJ0S5VY, Neo-Synephrine 12 Hour NTZ, Sch 9384, Duration 12 Hour Nasal Spray, MLS000038040, CHEBI:7863, Benzedrex Nasal Spray 12 Hour, EINECS 219-015-0, St. Joseph Nasal Spray for Children, Dristan Long Lasting Nasal Mist, SMR000059324, 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride, 2-(4-t-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazolinium chloride, 2,6-Dimethyl-2-(4-tertiarybutyl-3-hydroxyphenyl)methylimidazoline hydrochloride, 2-[3-Hydroxy-2,6-dimethyl-4-t-butyl-benzyl]-2-imidazoline, 6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol hydrochloride, 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol monohydrochloride, Phenol, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-, hydrochloride, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride, Phenol, 3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-6-(1,1-dimethylethyl)-2,4-dimethyl-, monohydrochloride, SCH-9384, SR-01000002705, Rhofade, Sinex, Anefrin nasal, afrinhydrochloride, Sudafed OM, Oximetazoline HCl, iliadinhydrochloride, Ocuclear (TN), Prestwick_373, Rhfade (TN), Opera_ID_32, 3-[(4,5-Dihydro-, SCHEMBL41247, MLS002222207, SPECTRUM1500453, AC1L24Z6, Oxymetazoline Hydrochloride,(S), CHEMBL1200791, CTK8G2231, HY-B0427A, DTXSID80177729, BEEDODBODQVSIM-UHFFFAOYSA-N, MolPort-000-709-375, HMS1568N09, HMS1920D18, Pharmakon1600-01500453, Tox21_500903, CCG-40216, MFCD00058147, NSC757254, AKOS000280887, Oxymetazoline hydrochloride (JAN/USP), CS-2533, KS-5222, LP00903, MCULE-1133105377, NSC-757254, Oxymetazoline hydrochloride [USAN:JAN], NCGC00094218-01, NCGC00094218-02, NCGC00094218-03, NCGC00094218-04, NCGC00094218-05, NCGC00261588-01, AN-10106, AB2000600, KB-221830, LS-104147, Oxymetazoline hydrochloride, >=99%, solid, EU-0100903, FT-0082561, Oxymetazoline hydrochloride [USAN:USP:JAN], V0297, D01022, O 2378, Oxymetazoline hydrochloride, analytical standard, 315O028, SR-01000002705-2, SR-01000002705-4, SR-01000002705-7, W-107424, 2-(4-t-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoliniumchloride, Sinex VapoSpray Moisturizing 12-Hour Decongestant UltraFine Mist, 2,6-dimethyl-2-(4-tertiarybutyl-3-hydroxyphenyl)methylimidazolinehydrochlori, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenohydrochloride, 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenolhydrochloride, Oxymetazoline hydrochloride, European Pharmacopoeia (EP) Reference Standard, 1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol hydrochloride, 2-(3-HYDROXY-2,6-DIMETHYL-4-TERT-BUTYLBENZYL)-2-IMIDAZOLINE HYDROCHLORIDE, 2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-1-ium chloride, 6-(tert-butyl)-3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,4-dimethylphenol hydrochloride, 6-tert-butyl-3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,4-dimethylphenol hydrochloride, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol hydrochloride, Oxymetazoline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Oxymetazoline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride, ST50993902, 6-(tert-butyl)-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol, chloride, AKOS015896004, A816594, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol; hydron; chloride, 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol; hydron; chloride

ID: 215

InChIKey: BEJNERDRQOWKJM-UHFFFAOYSA-N
SMILES: C1=C(OC=C(C1=O)O)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3840
synonyms found at PubChem are:
kojic acid, 501-30-4, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one, 5-Hydroxy-2-(hydroxymethyl)-4-pyrone, 5-Hydroxy-2-hydroxymethyl-4-pyrone, 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-, 5-hydroxy-2-(hydroxymethyl)pyran-4-one, acido kojico, 2-Hydroxymethyl-5-hydroxy-gamma-pyrone, 2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one, UNII-6K23F1TT52, CCRIS 4131, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone, NSC 1942, EINECS 207-922-4, BRN 0120895, 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one, AI3-02549, Pyran-4-one, 5-hydroxy-2-(hydroxymethyl), CHEMBL287556, CHEBI:43572, NSC1942, BEJNERDRQOWKJM-UHFFFAOYSA-N, 6K23F1TT52, 5-Hydroxy-2-hydroxymethyl-pyran-4-one, NCGC00017325-03, NCGC00017325-06, DSSTox_CID_20236, DSSTox_RID_79455, DSSTox_GSID_40236, 123712-78-7, CAS-501-30-4, KOJ, Kojisaeure, HSDB 7664, Kojic Acid Solution, Spectrum_000191, AC1Q7BYS, AC1Q7BYT, Spectrum2_001828, Spectrum3_001704, Spectrum4_000571, Spectrum5_001085, D0F3CO, Kojic acid, 99% 5g, AC1L1GU2, Kojic Acid Dipalmitate 5kg, Oprea1_038773, SCHEMBL36895, BSPBio_003288, KBioGR_001002, KBioSS_000671, 5-18-02-00516 (Beilstein Handbook Reference), BIDD:ER0501, DivK1c_000923, SPBio_001875, Kojic acid, analytical standard, MEGxm0_000388, WLN: T6O DVJ B1Q EQ, DTXSID2040236, ACon1_000622, BEJNERDRQOWKJM-UHFFFAOYSA-, HMS502O05, KBio1_000923, KBio2_000671, KBio2_003239, KBio2_005807, KBio3_002508, KS-00000GGK, MolPort-000-716-732, NINDS_000923, HMS3604L04, KUC106760N, EBD70941, NSC-1942, TNP00261, 2-Hydroxymethyl-5-hydroxy-?-pyrone, 2-Hydroxymethyl-5-Hydroxy-G-Pyrone, Tox21_110814, Tox21_113449, ANW-46611, BBL010645, BDBM50031467, CCG-38458, MFCD00006580, SBB005397, STK801688, ZINC13831818, 2-Hydroxymethyl-5-hydroxy-|A-pyrone, 2-Hydroxymethyl-5-Hydroxy-??-Pyrone, 2-Hydroxymethyl-5-hydroxy-beta-pyrone, AKOS000120649, Tox21_110814_1, 5-Hydroxy-2-(hydroxymethyl)-4-pyrond, DB01759, MCULE-1079267668, RTR-036891, IDI1_000923, SMP1_000171, NCGC00017325-01, NCGC00017325-02, NCGC00017325-04, NCGC00017325-05, NCGC00142361-01, NCGC00168903-01, NCGC00168903-02, NCGC00181145-01, AC-11658, AJ-64461, AN-45363, AS-11648, CJ-14474, H802, KB-53041, Kojic acid, purum, >=98.0% (HPLC), KSC-11-228-2, SC-81009, ST019399, 2-HYDROXYMETHYL-5-HYDROXY-4-PYRONE, 2-Hydroxymethyl-5-hydroxy-4H-pyran-4-one, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-, AB0010492, KB-197735, LS-127450, ST2412032, CS-0032701, FT-0081379, FT-0627581, K0010, K0012, 01K304, C14516, M-6079, SR-01000945134, SR-01000945134-1, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one Solution, C65A72E0-0E46-4AF4-AA68-178ECA2E5FCC, I14-19021, F0001-1307, Z381040328, Kojic acid pound>>5-hydroxy-2-(hydroxymethyl)-4h-pyran-4-on, InChI=1/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2

ID: 216

InChIKey: BEZZFPOZAYTVHN-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 40854
synonyms found at PubChem are:
Oxfendazole, 53716-50-0, Fenbendazole sulfoxide, Synanthic, Systamex, OFDZ, Repidose, Systemax, Oxfendazolum, Oxfendazol, Synanthic (Veterinary), fenbendazole S-oxide, RS 8858, RS-8858, 5-Phenylsulfinyl-2-carbomethoxyaminobenzimidazole, Oxfendazol [INN-Spanish], Oxfendazolum [INN-Latin], UNII-OMP2H17F9E, HOE 8105, methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate, Oxfendazole [USAN:BAN:INN], Methyl 5-(phenylsulfinyl)-2-benzimidazolecarbamate, Oxfendazole (USP/INN), EINECS 258-714-5, 5-(Phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester, Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate, (5-(Phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester, BRN 0761290, OMP2H17F9E, CHEMBL42442, Methyl (5-phenylsulfinyl)-1H-benzimidazol-2-yl carbamate, C15H13N3O3S, CHEBI:35812, methyl 5(6)-phenylsulfinyl-2-benzimidazolecarbamate, NCGC00095157-04, 2-Benzimidazolecarbamic acid, 5-(phenylsulfinyl)-, methyl ester, [5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester, CARBAMIC ACID, (5-(PHENYLSULFINYL)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER, Carbamic acid, [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester, DSSTox_CID_24112, DSSTox_RID_80103, DSSTox_GSID_44112, Q-201525, methyl N-[5-(benzenesulfinyl)-1H-benzimidazol-2-yl]carbamate, methyl N-[6-(benzenesulfinyl)-1H-benzimidazol-2-yl]carbamate, Carbamic acid, 5-(phenylsulfinyl)-1H-benzimidazol-2-yl-, methyl ester, CAS-53716-50-0, Oxfenbendazole, Oxphendazole, Benzelmin, Nanthic, CCRIS 9430, Synanthic (TN), Oxfendazole [USAN:USP:INN:BAN], Spectrum2_001704, Spectrum3_001972, Oprea1_563224, SCHEMBL44121, BSPBio_003572, MLS004712073, Synanthic [veterinary] (TN), SPECTRUM1505296, SPBio_001688, (+/-)-Fenbendazole Sulfoxide, AC1L24M4, SCHEMBL9818561, DTXSID9044112, CTK8E8695, KBio3_002947, BEZZFPOZAYTVHN-UHFFFAOYSA-N, MolPort-002-330-209, MolPort-003-666-629, HMS1922B08, HMS2090F19, HMS2093O16, HMS3655M14, HMS3715E09, Pharmakon1600-01505296, BCP09602, HY-B0291, Oxfendazole (Fenbendazole Sulfoxide), Tox21_113444, Tox21_302383, BDBM50300124, CCG-39503, NSC758943, s1830, STK378905, Fenbendazole Sulphoxide (Oxfendazole), AKOS005448898, AKOS015918230, Tox21_113444_1, AC-8715, AN-7766, CCG-220984, CS-2305, KS-5036, MCULE-2247044354, NSC-758943, NCGC00095157-01, NCGC00095157-02, NCGC00095157-03, NCGC00095157-05, NCGC00095157-06, NCGC00255714-01, BC203983, CC-33414, H844, LS-50557, SC-18524, SMR001550468, SBI-0206760.P001, AB0013301, AB2000317, TL8003524, TR-037021, FT-0630662, O0391, ST50865840, C21882, D05291, AB01275512-01, AB01275512_02, AB01275512_03, Oxfendazole, VETRANAL(TM), analytical standard, 716O500, A829749, C-19436, SR-01000872713, I14-7817, SR-01000872713-1, BRD-A33447119-001-02-5, BRD-A33447119-001-03-3, BRD-A33447119-001-05-8, Methyl (5-Benzenesulfinyl-2-benzimidazol-yl)carbamate, Methyl [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamate, methoxy-N-[5-(phenylsulfinyl)benzimidazol-2-yl]carboxamide, Oxfendazole, European Pharmacopoeia (EP) Reference Standard, methyl (6-(phenylsulfinyl)-1H-benzo[d]imidazol-2-yl)carbamate, methyl 5-(phenylsulfinyl)-1H-benzo[d]imidazol-2-ylcarbamate, METHYL 6-(PHENYLSULFINYL)-1H-BENZIMIDAZOL-2-YLCARBAMATE, methyl 6-(phenylsulfinyl)-1H-benzo[d]imidazol-2-ylcarbamate, methyl N-[6-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate, [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamic Acid Methyl Ester, Methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate, 9CI, methyl N-[5-(benzenesulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate, Oxfendazole, United States Pharmacopeia (USP) Reference Standard, Carbamic acid, N-[6-(phenylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester, N-[6-(benzenesulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester

ID: 217

InChIKey: BFCBHPPLWHZOIQ-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)C2=C(O1)C(=C(C=C2OC)OC)OC)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6728948
synonyms found at PubChem are:
2-METHYL-5,7,8-TRIMETHOXYISOFLAVONE, SPBio_001933, AC1O9AUC, Spectrum2_001927, Spectrum5_001798, SPECTRUM200215, SCHEMBL4283593, CHEMBL1559418, CCG-39462, NCGC00095805-01, 5,7,8-trimethoxy-2-methyl-3-phenylchromen-4-one

ID: 218

InChIKey: BFPSDSIWYFKGBC-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(=C(C2=CC=C(C=C2)OC)Cl)C3=CC=C(C=C3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11289
synonyms found at PubChem are:
chlorotrianisene, Chlortrianizen, Chlortrianisestrol, Chlorotrianisine, 569-57-3, TACE, Chlorestrolo, Chlorotrianizen, Chlortrianisen, Chloortrianisestrol, Clorotrisin, Hormonisene, Khlortrianizen, Clorestrolo, Merbentul, Anisene, Metace, Rianil, Chlortrianisoestrolum, Chlortrianisene, Chlorotrisin, Chlortrianisenum, Tace-fn, Tri-p-anisylchloroethylene, Clorotrianiseno, Chlorotrianisenum, Clorotrianisene, Trianisestrol, Triagen, Tris(p-methoxyphenyl)chloroethylene, Chlorotrianisenum [INN-Latin], Tace (pharmaceutical), Clorotrianiseno [INN-Spanish], Chlorotris(p-methoxyphenyl)ethylene, Clorotrianisene [DCIT], NSC-10108, Ethylene, chlorotris(p-methoxyphenyl)-, chlorotrianisestrol, Chlorotrianisene [INN:BAN], CCRIS 4769, CTA, HSDB 3302, Chlorotrianisene (INN), UNII-6V5034L121, EINECS 209-318-6, TACE (TN), 1,1',1''-(1-Chloro-1-ethenyl-2-ylidene)-tris(4-methoxybenzene), Benzene, 1,1',1''-(1-chloro-1-ethenyl-2-ylidene)tris(4-methoxy)-, BRN 1891845, Chlorotrianisene [Nonsteroidal oestrogens], MLS000028625, CHEBI:3641, NCGC00016511-02, CAS-569-57-3, SMR000058658, 1,1',1''-(2-chloroethene-1,1,2-triyl)tris(4-methoxybenzene), 1-[2-chloro-1,2-bis(4-methoxyphenyl)ethenyl]-4-methoxybenzene, Benzene, 1,1',1''-(1-chloro-1-ethenyl-2-ylidene)tris[4-methoxy-, 6V5034L121, 1,1',1''-(2-chloroethene-1,1,2-triyl)tris[4-(methyloxy)benzene], DSSTox_CID_1299, DSSTox_RID_76067, DSSTox_GSID_21299, 4,4',4''-(2-chloroethene-1,1,2-triyl)tris(methoxybenzene), 1-[1-chloro-2,2-bis(4-methoxyphenyl)ethenyl]-4-methoxybenzene, Benzene, 1,1',1''-(1-chloro-1-ethenyl-2-ylidene)tris(4-methoxy-, Benzene, 1,1',1'-(1-chloro-1-ethenyl-2-ylidene)tris(4-methoxy)-, Chlorotrianisene [BAN:INN], SR-01000721940, Chlorotrianisene [USP:INN:BAN], Prestwick_22, Spectrum_000136, AC1Q3FDW, Chlorotrianisene, ~95%, Opera_ID_1728, Prestwick0_000757, Prestwick1_000757, Prestwick2_000757, Prestwick3_000757, Spectrum2_000704, Spectrum3_000343, Spectrum4_000954, Spectrum5_000711, D0X0KJ, AC1L1X1E, SCHEMBL8225, BSPBio_000774, BSPBio_002005, KBioGR_001568, KBioSS_000596, 4-06-00-07650 (Beilstein Handbook Reference), MLS002415722, SPECTRUM1500181, SPBio_000887, SPBio_002713, BPBio1_000852, GTPL7146, CHEMBL1200761, DTXSID1021299, KBio2_000596, KBio2_003164, KBio2_005732, KBio3_001225, BFPSDSIWYFKGBC-UHFFFAOYSA-N, MolPort-001-783-515, HMS1570G16, HMS1920K17, HMS2091C20, HMS2097G16, HMS2230L03, HMS3371E11, HMS3714G16, BCP13708, NSC10108, ZINC1530598, Tox21_110466, Tox21_202361, Tox21_302897, CCG-40079, LS-226, s4629, WLN: 1OR DYGUYR DO1&R DO1, AKOS015960863, Tox21_110466_1, API0001964, DB00269, NCGC00016511-01, NCGC00016511-03, NCGC00016511-04, NCGC00016511-05, NCGC00016511-08, NCGC00091333-01, NCGC00091333-02, NCGC00091333-03, NCGC00256381-01, NCGC00259910-01, AC-12512, BC204747, CJ-23983, SBI-0051309.P003, AB00051941, B5912, FT-0632409, D00269, 162370-EP2280006A1, 162370-EP2281813A1, 569C573, C-50387, SR-01000721940-2, SR-01000721940-3, 1,1',1''(1-Chloro-1-ethenyl-2-ylidene)tris[4-methoxybenzene], 1-[2-Chloro-1,2-bis(4-methoxyphenyl)vinyl]-4-methoxybenzene #, Benzene,1',1''-(1-chloro-1-ethenyl-2-ylidene)tris[4-methoxy-

ID: 219

InChIKey: BFSMWENDZZIWPW-UHFFFAOYSA-N
SMILES: CC(C)[N+](C)(CCC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)N)C(C)C.[I-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6284
synonyms found at PubChem are:
Isopropamide Iodide, 71-81-8, Darbid, Isoproponum iodide, Priamide Eupharma, Dipramid, Dipramide, Piaccamide, Priamide, Priazimide, Sanulcin, Tyrimide, Isamid, Marygin-M, UNII-E0KNA372SZ, Isopropamide ioduro [DCIT], Isopropamidi iodidum [INN-Latin], SKF 4740, Iodure d'isopropamide [INN-French], EINECS 200-766-8, NSC 15521, Ioduro de isopropamida [INN-Spanish], 5579 MD, E0KNA372SZ, R 79, MLS000069749, (3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium iodide, Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma-phenyl-, iodide, SMR000058752, AMMONIUM, (3-CARBAMOYL-3,3-DIPHENYLPROPYL)DIISOPROPYLMETHYL-, IODIDE, 5579 M.D., C23H33N2O, Isopropamide ioduro, Isopropamidi iodidum, Iodure d'isopropamide, Ioduro de isopropamida, SR-01000759196, 4-[bis(methylethyl)methylamino]-2,2-diphenylbutanamide, iodide, Isopropamide iodide [INN:BAN:JAN], Darbid (TN), Isopropamide iodide [USP:INN:BAN:JAN], Opera_ID_466, D0Z9PX, AC1L1M6X, MLS001148464, MLS002222289, SCHEMBL100255, SPECTRUM1500356, CHEBI:6044, CHEMBL1200347, HMS500L22, DTXSID30221221, HMS1570I22, HMS1920H11, HMS2091N21, HMS2097I22, HMS2235K22, HMS3372J16, HMS3714I22, Pharmakon1600-01500356, Isopropamide iodide (JAN/USP/INN), CCG-40128, MFCD00063513, NSC757066, SBB058159, AKOS024374947, API0003043, MCULE-3737293050, NSC-757066, NCGC00094702-01, NCGC00094702-02, 5579 M.D, LS-17001, I1048, ST51015028, D01005, SR-01000759196-2, SR-01000759196-4, Ammonium iodide, (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl-, (4-amino-4-oxo-3,3-diphenylbutyl)-methyl-di(propan-2-yl)azanium iodide, (4-amino-4-oxo-3,3-diphenylbutyl)-methyl-di(propan-2-yl)azanium,iodide, (4-amino-4-oxo-3,3-diphenylbutyl)-methyl-di(propan-2-yl)azanium;iodide, 4-Amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenyl-1-butanaminium Iodide, Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma -phenyl-, iodide, Benzenepropanaminium, gamma-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-gamma -phenyl-, iodide (9CI)

ID: 220

InChIKey: BFUUJUGQJUTPAF-UHFFFAOYSA-N
SMILES: CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 22169
synonyms found at PubChem are:
Keracaine, Alcaine, Chibro-Heracaine, EINECS 227-541-7, Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride, 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride, beta-(Diethylamino)ethyl 3-amino-4-n-propoxybenzoate hydrochloride, BENZOIC ACID, 3-AMINO-4-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE, AC1L2JUT, AC1Q1SK4, C16H26N2O3.HCl, proxymetacaine monohydrochloride, MolPort-005-979-908, Proparacaine hydrochloride [USAN], AKOS026749832, MCULE-8418206804, LS-36010, 2-(3-amino-4-propoxybenzoyl)oxyethyl-diethylazanium chloride, Proparacaine hydrochloride, 5875-06-9, Proparacaine Hcl, Proxymetacaine hydrochloride, Ophthain, 2-(Diethylamino)ethyl 3-Amino-4-propoxybenzoate Hydrochloride, Proparacaine (Hydrochloride), UNII-U96OL57GOY, U96OL57GOY, 2-(diethylamino)ethyl3-amino-4-propoxybenzoate hydrochloride, Alcaine (TN), DSSTox_CID_28948, DSSTox_RID_83213, DSSTox_GSID_49022, C16H27ClN2O3, Proparacaine hydrochloride (USP), Proparacaine hydrochloride [USP], 2-Diethylaminoethyl 3-amino-4-propoxybenzoate hydrochloride, 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride, SMR000875264, CAS-5875-06-9, NCGC00016991-03, Fluoracaine, 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate;hydrochloride, Chibro-keracaine, Ophthetic (TN), Proparacaine, HCl, PubChem15202, AC1LAOF2, SCHEMBL93880, MLS001333067, MLS001333068, MLS002154072, 499-67-2 (Parent), Jsp000037, CHEMBL1200464, DTXSID0049022, CTK8E3427, BFUUJUGQJUTPAF-UHFFFAOYSA-N, MolPort-003-666-736, HMS1570P20, Pharmakon1600-01505688, KS-00000XJ2, Tox21_113547, ACM499672, MFCD00083467, NSC759896, s1828, AKOS015844989, Tox21_113547_1, AC-3399, API0003948, CCG-213513, CS-2303, KS-5058, NC00586, NSC-759896, NCGC00016991-05, AN-13015, CPD000875264, HY-66012, Proxymetacaine hydrochloride, Proparacaine, SAM002564232, AB2000315, TC-010846, P2156, Proparacaine hydrochloride, analytical standard, D02098, K-0087, 875P069, A832009, C-55249, 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate HCl, I01-1787, SR-05000001759-3, 2-(diethylamino)ethyl 3-amino-4-propoxy-benzoate hydrochloride, 2-(diethylamino)ethyl 3-azanyl-4-propoxy-benzoate hydrochloride, 2-diethylaminoethyl 3-amino-4-propoxy-benzoate hydrochloride, Benzoic acid,3-amino-4-propoxy-,2-(diethylamino)ethyl ester, 3-amino-4-propoxybenzoicacid2-(diethylamino)ethylesterhydrochloride, 3-Amino-4-propoxybenzoic Acid 2-(Diethylamino)ethyl Ester Hydrochloride, Proparacaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

ID: 221

InChIKey: BGDKAVGWHJFAGW-UHFFFAOYSA-N
SMILES: CCN(CC1=CC=NC=C1)C(=O)C(CO)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5593
synonyms found at PubChem are:
tropicamide, 1508-75-4, Mydriacyl, Mydriaticum, Mydriafair, Tropicacyl, Minims tropicamide, Bistropamide, Epitromina, Tropicamidum, Mydrum, Visumidriatic, Tropicamida, Tropikamid, Tropimil, Paremyd, N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide, Tropicamid, Ro 1-7683, Ocu-Tropic, Tropicamidum [INN-Latin], Tropicamida [INN-Spanish], N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, Opticyl, Spectro-Cyl, I-Picamide, Triaminic DM, Mydriacyl (TN), N-Ethyl-N-(4-pyridylmethyl)tropamid, N-Ethyl-N-(4-pyridylmethyl)tropamide, n-ethyl-n-(g-picolyl)tropamide, Tropicamide [USAN:INN:BANJAN], EINECS 216-140-2, N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide, BRN 0285563, BGDKAVGWHJFAGW-UHFFFAOYSA-N, Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-, N-Ethyl-2-phenyl-N-4-[-pyridyl-methyl]hydracrylamide, Hydracrylamide, N-ethyl-2-phenyl-N-(4-pyridylmethyl)-, (+-)-N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, NCGC00016065-07, Benzeneacetamide, N-ethyl-.alpha.-(hydroxymethyl)-N-(4-pyridinylmethyl)-, T 9778, DSSTox_CID_25220, DSSTox_RID_80757, DSSTox_GSID_45220, Q-201902, N-ethyl-3-hydroxy-2-phenyl-N-(4-pyridylmethyl)propanamide, Mydral, OcuTropic, Ocu Tropic, Tropicamide Faure, Tropicamide Minims, Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-, (+-)-, SMR000058523, Tropicamide Monofree, Colircusi Tropicamida, SR-01000075351, Tropicamide, (R)-Isomer, Tropicamide, (S)-Isomer, Tropicamide, (+-)-Isomer, Tropicamide, solid, Prestwick_487, CAS-1508-75-4, component of Paremyd, Tropicamide [USAN:USP:INN:BAN:JAN], Spectrum_000584, Tropicamide Alcon Brand, Tropicamide Rivex Brand, Tropicamide Monohydrochloride, (R)-Isomer, Tropicamide Monohydrochloride, (S)-Isomer, Tropicamide Ocumed Brand, AC1L1KOZ, AC1Q5IFA, Prestwick0_000228, Prestwick1_000228, Prestwick2_000228, Prestwick3_000228, Spectrum2_000936, Spectrum3_000655, Spectrum4_000377, Spectrum5_001585, Tropicamide Chauvin Brand, Tropicamide Novartis Brand, Akorn Brand of Tropicamide, Alcon Brand of Tropicamide, D09PNY, Rivex Brand of Tropicamide, Ocumed Brand of Tropicamide, Tropicamide Pharmafair Brand, Chauvin Brand of Tropicamide, Ocusoft Brand of Tropicamide, Lopac0_001223, SCHEMBL23975, BSPBio_000275, BSPBio_002289, KBioGR_000873, KBioSS_001064, 5-22-09-00359 (Beilstein Handbook Reference), MLS001306442, MLS002154240, Novartis Brand of Tropicamide, DivK1c_000448, SPECTRUM1500599, SPBio_000872, SPBio_002196, Stulln Brand 1 of Tropicamide, Stulln Brand 2 of Tropicamide, BPBio1_000303, CHEBI:9757, GTPL7319, Pharmafair Brand of Tropicamide, Tropicamide (JP15/USP/INN), Tropicamide (JP17/USP/INN), CHEMBL1200604, DTXSID8045220, BDBM82371, CTK4C6796, HMS501G10, KBio1_000448, KBio2_001064, KBio2_003632, KBio2_006200, KBio3_001509, Bournonville Brand of Tropicamide, MolPort-000-159-321, NINDS_000448, HMS1568N17, HMS1921I09, HMS2089M05, HMS2092A18, HMS2095N17, HMS2235J15, HMS3259M18, HMS3263F08, HMS3267A13, HMS3373B07, HMS3651K04, HMS3712N17, Pharmakon1600-01500599, BCP13504, EBD22886, HY-B0321, KS-00000H8Q, NSC_5593, Tox21_110297, Tox21_501223, AC-816, BBL028074, BG0349, CCG-40076, MFCD00058580, NSC757372, s1913, STK934612, AKOS005664076, Tox21_110297_1, ACN-036667, AM84467, API0004531, CS-2362, DB00809, KS-5174, LP01223, MCULE-4102613027, NC00589, NSC-757372, RP29909, Cahill May Roberts Brand of Tropicamide, IDI1_000448, Medical Ophthalmics Brand of Tropicamide, SMP1_000304, NCGC00016065-03, NCGC00016065-04, NCGC00016065-05, NCGC00016065-06, NCGC00016065-08, NCGC00016065-09, NCGC00016065-11, NCGC00024866-02, NCGC00024866-03, NCGC00024866-04, NCGC00024866-05, NCGC00024866-06, NCGC00261908-01, AK164485, AN-15530, CPD000058523, LS-28545, SAM002564235, CAS_1508-75-4, SBI-0051190.P003, AB0011259, AB2000370, TL8001101, AB00052120, EU-0101223, FT-0657590, ST51015162, D00397, K-4793, AB00052120-10, AB00052120_11, AB00052120_12, 508T754, L001262, I06-0811, SR-01000075351-1, SR-01000075351-3, SR-01000075351-5, SR-01000075351-7, BRD-A79672927-001-05-8, BRD-A79672927-001-10-8, Tropicamide, European Pharmacopoeia (EP) Reference Standard, N-Ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide #, Benzeneacetamide,N-ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)-, Tropicamide, United States Pharmacopeia (USP) Reference Standard, Tropicamide for peak identification, European Pharmacopoeia (EP) Reference Standard

ID: 222

InChIKey: BGEBZHIAGXMEMV-UHFFFAOYSA-N
SMILES: COC1=C2C=CC(=O)OC2=CC3=C1C=CO3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2355
synonyms found at PubChem are:
Bergapten, 5-Methoxypsoralen, 484-20-8, bergaptene, Heraclin, Majudin, 4-Methoxy-7H-furo[3,2-g]chromen-7-one, BERGAPTAN, Psoraderm, 5-Mop, O-Methylbergaptol, 5-Methoxy psoralen, 5-Methoxy-6,7-furanocoumarin, 5-Methoxyfuranocoumarin, Pentaderm, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-methoxy-, 4-Methoxy-7H-furo(3,2-g)(1)benzopyran-7-one, 4-Methoxyfuro[3,2-g]benzopyran-7-one, 5-methoxypsoralene, 4-methoxyfuro[3,2-g]chromen-7-one, UNII-4FVK84C92X, NSC 95437, Bergaptene (DCF), CCRIS 4348, HSDB 3466, 5-Methoxypsoralen with ultraviolet A therapy, NSC95437, 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone, EINECS 207-604-5, 4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-methoxy-, BRN 0019560, CHEMBL24171, 4FVK84C92X, BGEBZHIAGXMEMV-UHFFFAOYSA-N, 4-Methoxy-furo[3,2-g]chromen-7-one, 5-methoxyfurano[3,2-g]chromen-2-one, 4-Methoxyfuro[3,2-g]benzopyrane-7-one, 5-methoxy-2H-furo[3,2-g]chromen-2-one, DSSTox_CID_5560, DSSTox_RID_77830, DSSTox_GSID_25560, Q-100536, CAS-484-20-8, SMR000112435, SR-05000002173, Geralen, Bergapten(e), 5 methoxypsoralen, Pentaderm (TN), 5-methoxy-psoralen, Spectrum_000794, AC1L1DHU, Spectrum2_000534, Spectrum3_000663, Spectrum4_001478, Spectrum5_000155, 5-Methoxypsoralen, 99%, bmse000758, D0QR5G, AC1Q47BC, 5-Methoxypsoralen (obsol.), 7H-Furo[3, 4-methoxy-, Oprea1_562364, SCHEMBL50066, BSPBio_002325, KBioGR_002055, KBioSS_001274, SPECTRUM300546, 5-19-06-00004 (Beilstein Handbook Reference), MLS002207272, MLS002454380, Bergapten, analytical standard, DivK1c_000529, 5-Methoxypsoralen (Bergapten), SPBio_000547, MEGxp0_000990, DTXSID1025560, ACon0_000984, ACon1_001979, CHEBI:18293, CTK3J2399, HMS501K11, KBio1_000529, KBio2_001274, KBio2_003842, KBio2_006410, KBio3_001545, KS-00000GSD, ZINC57731, MolPort-000-880-879, NINDS_000529, HMS1923G13, HMS2268M24, HMS3652F19, Pharmakon1600-00300546, HY-N0370, TNP00299, Tox21_202357, Tox21_303255, ANW-42611, BDBM50067880, CCG-39946, MFCD00010272, NSC-95437, NSC755877, s4239, STK333038, AKOS000276715, AN-9448, CB-1199, CS-2234, DB12216, DS-2970, LS-1292, MCULE-7768334865, NSC-755877, RTR-017690, SDCCGMLS-0066492.P001, IDI1_000529, NCGC00017357-01, NCGC00017357-02, NCGC00017357-03, NCGC00017357-04, NCGC00017357-05, NCGC00017357-06, NCGC00017357-07, NCGC00017357-08, NCGC00091582-01, NCGC00091582-02, NCGC00091582-03, NCGC00091582-04, NCGC00178705-01, NCGC00178705-02, NCGC00256998-01, NCGC00259906-01, 4CN-0945, AC-20189, AJ-09777, AK134854, BAS 00674110, CC-24574, CJ-00484, NCI60_042121, SC-46077, ST057259, ZB002242, SBI-0051583.P002, 4-methoxy-7-furo[3,2-g][1]benzopyranone, AB0019675, AX8014410, ST2411501, TR-017690, 4-Methoxy-7H-furo[3,2-g]benzopyran-7-one, B2840, FT-0603416, N1304, V0122, 4-Methoxy-7H-furo[3,2-g]chromen-7-one #, C01557, D07521, M-9412, AB00052148_06, AB00052148_07, 484B208, A827532, C-11626, SR-05000002173-2, SR-05000002173-3, SR-05000002173-5, BRD-K12968785-001-02-6, BRD-K12968785-001-03-4, BRD-K12968785-001-06-7, BRD-K12968785-001-11-7, I14-13388, 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, .gamma.-lactone, InChI=1/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H

ID: 223

InChIKey: BGKFPRIGXAVYNX-UHFFFAOYSA-N
SMILES: C1=C(C=C2C(=C1Cl)C(=O)C=C(N2)C(=O)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1779
synonyms found at PubChem are:
5,7-Dichlorokynurenic acid, 131123-76-7, 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, 5,7-Dcka, 5,7-Dichloroquinurenic acid, 5,7-Dichorokynurenic acid, UNII-T61ORK73PY, C10H5Cl2NO3, 5,7-Dichloro-4-hydroxy-2-quinolinecarboxylic acid, DCKA, T61ORK73PY, CHEMBL50267, 2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-, DCKA, 5,7-DICHLOROKYNURENIC ACID, 5,7-dichloro-4-hydroxy-2-carboxyquinoline, 123158-59-8, 2-Quinolinecarboxylicacid, 5,7-dichloro-4-hydroxy-, 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid, 1pbq, DK1, SR-01000075445, 5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid anion, Spectrum_001455, Tocris-0286, SpecPlus_000760, Lopac-D-138, AC1Q3MQK, Spectrum2_001999, Spectrum3_001736, Spectrum4_000085, Spectrum5_001096, ACMC-20c86a, Biomol-NT_000180, D04DHB, AC1L1C7X, 5,7 Dichlorokynurenic Acid, Lopac0_000438, Oprea1_091974, BSPBio_003412, KBioGR_000350, KBioSS_001935, DivK1c_006856, SCHEMBL158714, SPECTRUM1502062, SPBio_002217, BPBio1_001172, GTPL2361, SCHEMBL8369562, CTK0H5001, KBio1_001800, KBio2_001935, KBio2_004503, KBio2_007071, KBio3_002632, CHEBI:107660, MolPort-003-813-118, HMS3261G18, HMS3266E21, ZINC8660423, Tox21_500438, BDBM50001266, BN0032, CCG-39537, PDSP1_000183, PDSP2_000182, AKOS012682248, AKOS015913821, DB01931, LP00438, NCGC00015313-01, NCGC00015313-02, NCGC00015313-03, NCGC00015313-04, NCGC00015313-05, NCGC00015313-06, NCGC00015313-07, NCGC00015313-08, NCGC00024525-01, NCGC00024525-02, NCGC00024525-03, NCGC00024525-04, NCGC00024525-05, NCGC00024525-06, NCGC00261123-01, AJ-75026, DB-062804, LS-172791, RT-010010, B6247, EU-0100438, FT-0739743, FT-0743570, A13926, 2-Quinolinecarboxylicacid,5,7-dichloro-4-hydroxy-, 5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid, J-005939, SR-01000075445-1, SR-01000075445-3, BRD-K60287130-001-03-2, BRD-K60287130-001-04-0, BRD-K60287130-001-05-7, I14-44484, 5,7-dichloro-1,4-dihydro-4-oxo-2-Quinolinecarboxylic acid, 5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid(DCKA), 5,7-Dichloro-4-hydroxy-quinoline-2-carboxylicacidethylester, 2-Quinolinecarboxylic acid, 5,7-dichloro-1,4-dihydro-4-oxo-, 5,7-Dichloro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid

ID: 224

InChIKey: BGKHCLZFGPIKKU-LDDQNKHRSA-N
SMILES: CCCCC[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281912
synonyms found at PubChem are:
prostaglandin A1, PGA1, 14152-28-4, PGA(sub 1), PGA(sup 1), Prostaglandin A(sub 1), Prostaglandin A(sup 1), UNII-VYR271N44P, Prostaglandin E(sup 1)-217, 15a-Hydroxy-9-oxo-10,13E-prostadienoate, VYR271N44P, CHEBI:15545, 15a-Hydroxy-9-oxo-10,13E-prostadienoic acid, (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-, 9-oxo-15S-hydroxy-10Z,13E-prostadienoic acid, 3-Cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-, Prostaglandin E1-217, PGA1 (Prostaglandin A1), CHEMBL1084644, AC1NQZA9, Prostaglandin A1 synthetic, (13E)-(15S)-15-Hydroxy-9-oxoprosta-10,13-dienoate, Prostaglandin A1, synthetic, BSPBio_001458, BML1-F01, SCHEMBL6417548, Eicosanoids_PGA1_C20H32O4, BGKHCLZFGPIKKU-LDDQNKHRSA-N, HMS1361I20, HMS1791I20, HMS1989I20, HMS3402I20, HMS3648A03, ZINC4096507, 1998AH, LMFA03010005, MFCD00077858, CCG-208253, IDI1_033928, NCGC00161282-01, NCGC00161282-02, NCGC00161282-03, 15-hydroxy-9-oxoprosta-10,13-dienoate, LS-58328, 15a-Hydroxy-9-ketoprosta-10,13-dienoate, 15-hydroxy-9-oxoprosta-10,13-dienoic acid, 15a-Hydroxy-9-ketoprosta-10,13-dienoic acid, SR-01000946186, J-007508, SR-01000946186-1, BRD-K04010869-001-02-6, (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoic acid, (13E,15S)-15-hydroxy-9-oxo-Prosta-10,13-dien-1-oate, (13E,15S)-15-hydroxy-9-oxo-Prosta-10,13-dien-1-oic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-3- cyclopentene-1-heptanoate, 2-(3-hydroxy-1-octenyl)-5-oxo-3-Cyclopentene-1-heptanoate, 2-(3-hydroxy-1-octenyl)-5-oxo-3- cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-3-Cyclopentene-1-heptanoic acid, Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)- (9CI), Prostaglandin A1, United States Pharmacopeia (USP) Reference Standard, 7-((1R,2S)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-enyl)heptanoic acid, 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopent-3-en-1-yl]heptanoic acid, 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid

ID: 225

InChIKey: BGMZEOAHMJFCCM-XDIVRLSYSA-N
SMILES: C[C@@]12CCC3[C@@]4(C(CC(=O)[C@]3(C15C(O5)C(=O)O[C@H]2C6=COC=C6)C)C([C@H]7[C@@H](C4=O)O7)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708645
synonyms found at PubChem are:
KBio1_001339, SpecPlus_000299, DivK1c_006395, EPOXY (2,3alpha)-7-DEACETOXY-7-OXODIHYDROISOGEDUNIN

ID: 226

InChIKey: BGPGVBLFHMZCNG-LIWIJTDLSA-N
SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C3=CC(=C(C=C3)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6419899
synonyms found at PubChem are:
Convolamine hydrochloride, Convolvamine hydrochloride, 5896-59-3, Prestwick_127, AC1O4WG1, Veratroyltropine hydrochloride, DTXSID60423559, HMS1569H14, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3,4-dimetho, (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3,4-dimethoxybenzoate hydrochloride, [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3,4-dimethoxybenzoate hydrochloride, 3,4-Dimethoxy-benzoic acid (1S,5R)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester hydrochloride, benzoic acid, 3,4-dimethoxy-, (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride

ID: 227

InChIKey: BGRJTUBHPOOWDU-UHFFFAOYSA-N
SMILES: CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5355
synonyms found at PubChem are:
sulpiride, 15676-16-1, Sulpyrid, Sulpirid, Aiglonyl, Dolmatil, Dogmatil, Guastil, Mirbanil, Misulvan, Sursumid, Abilit, Dobren, Eglonyl, Meresa, Miradol, Neogama, Omperan, Splotin, (+/-)-Sulpiride, Coolspan, Dogmatyl, Psicocen, Pyrkappl, Sernevin, (RS)-(+/-)-sulpiride, Calmoflorine, Alimoral, Championyl, Darleton, Desmenat, Eusulpid, Fardalan, Isnamide, Kylistro, Lisopiride, Mariastel, Norestran, Ozoderpin, Stamonevrol, Sulpirida, Sulpiridum, Sulpitil, Zemorcon, Dresent, Eglonil, Enimon, Equilid, Fidelan, Normum, Nufarol, Omiryl, Restful, Suprium, Valirem, Sulpiridum [INN-Latin], Sulpirida [INN-Spanish], Synedil, N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide, Pyrikappl, dl-sulpiride, RD 1403, Levosulpiridum [INN-Latin], Levosulpirida [INN-Spanish], CCRIS 4248, R.D. 1403, Sulpiride [USAN:INN:BAN:JAN], CHEMBL26, EINECS 239-753-7, N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide, Levosulpiride [INN], N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide, BRN 0494008, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide, Sulperide, Sulpor, Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, C15H23N3O4S, CHEBI:32168, BGRJTUBHPOOWDU-UHFFFAOYSA-N, Benzamide, 5-(aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-, o-Anisamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-, Levosulpirida, Levosulpiridum, Levobren, Sulpride, Sulpiride-R, Dogmatyl (TN), Magnetic resonance imaging sulpiride, N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoyl-benzamide, (+)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoyl-benzamide, 5-(Aminosufonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, SMR000038923, SULPIRIDE,(+), SR-01000075402, (y)-Sulpiride, Sulpiride, SLP, (plusmn)-sulpiride, RV-12309, (?)-Sulpiride, Prestwick_431, (+-)-sulpiride, CAS-15676-16-1, R. D. 1403, S 8010, PubChem17241, (.+/-.)-Sulpiride, Prestwick0_000056, Prestwick1_000056, Prestwick2_000056, Prestwick3_000056, SULPIRIDE,(-), Biomol-NT_000037, Biomol-NT_000162, SCHEMBL8421, DSSTox_CID_22574, DSSTox_RID_80050, DSSTox_GSID_42574, Lopac0_001050, Oprea1_602476, BSPBio_000211, (RS)-(A+/-)-Sulpiride, 5-22-08-00105 (Beilstein Handbook Reference), MLS000069434, MLS001306443, DivK1c_000278, SPBio_002132, AC1L1K62, BPBio1_000233, BPBio1_000463, BPBio1_001255, CCRIS-4248, GTPL5501, Sulpiride (JP17/USAN/INN), DTXSID1042574, BDBM11638, CTK8F2082, HMS500N20, KBio1_000278, KS-00000YBQ, Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoyl-, S-(-)-, MolPort-002-070-475, NINDS_000278, o-ANISAMIDE, N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-5-SULFAMOYL-, (S)-(-)-, Sulpiride 1.0 mg/ml in Methanol, HMS1568K13, HMS2095K13, HMS2231K07, HMS3263A22, HMS3266P12, HMS3371P16, HMS3372O01, HMS3393A08, HMS3651G12, HMS3712K13, BCP04500, BCP13871, HY-B1019, ( inverted question mark)-Sulpiride, Tox21_302205, Tox21_501050, BG0324, MFCD00055061, s4655, STK368596, AKOS004912732, AN-1017, AN-1019, API0003468, CCG-205127, CS-4534, DB00391, LP01050, MCULE-7506797476, IDI1_000278, NCGC00015966-03, NCGC00015966-04, NCGC00015966-05, NCGC00015966-06, NCGC00015966-07, NCGC00015966-08, NCGC00024852-02, NCGC00024852-03, NCGC00024852-04, NCGC00024852-05, NCGC00255813-01, NCGC00261735-01, AC-12181, LS-20058, LS-20059, AB0105833, KB-295026, EU-0001755, EU-0101050, FT-0652244, S0501, D01226, J10067, 676S161, L000579, I06-0054, SR-01000075402-2, SR-01000075402-3, SR-01000075402-6, BRD-A55272860-001-03-9, BRD-A55272860-001-04-7, BRD-A55272860-001-08-8, Z84655412, Sulpiride, British Pharmacopoeia (BP) Reference Standard, 1-ethyl-2-(2-methoxy-5-sulfamoylbenzamidomethyl)pyrrolidine, Sulpiride, European Pharmacopoeia (EP) Reference Standard, N-(((S)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide, N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide, N-1-(Ethylpyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoylbenzamide, (+/-)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide, (+/-)-N-1-(Ethylpyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoylbenzamide, 5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-benzamide, Benzamide,5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (+/-)-5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, (RS)-(+/-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, 5-(Aminosulfonyl)-N-[(1-ethyl-2- pyrrolidinyl)methyl]-2-methoxy- benzamide, Benzamide, 5-(aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-, (S)-, ( inverted question mark)-5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

ID: 228

InChIKey: BHZFZYLBVSWUMT-ZCFIWIBFSA-N
SMILES: C[C@@H]1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6603980
synonyms found at PubChem are:
quazinone, 70018-51-8, UNII-D1Q7F6C2FP, D1Q7F6C2FP, NCGC00094280-01, Ro 13-6438, Quazinonum, Quazinona, Quazinonum [Latin], Quazinona [Spanish], Quazinone [USAN:INN], Quazinone, powder, Quazinone (USAN/INN), Lopac-Q-3504, Ro 13-6438/006, DSSTox_CID_25795, DSSTox_RID_81135, DSSTox_GSID_45795, Lopac0_000980, SCHEMBL120976, 6-chloro-3-methyl-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one, AC1O7G69, CHEMBL320341, DTXSID6045795, HMS3263C21, ZINC3874826, Tox21_111263, Tox21_500980, (R)-6-Chloro-1,5-dihydro-3-methylimidazo(2,1-b)quinazolin-2(3H)-one, API0008548, CCG-205060, LP00980, Ro-136438, NCGC00015875-01, NCGC00094280-02, NCGC00094280-03, NCGC00261665-01, CAS-70018-51-8, Ro-136438006, EU-0100980, FT-0630793, D05668, Q 3504, SR-01000076099, SR-01000076099-1, (3R)-6-chloro-3-methyl-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one, (3r)-6-chloro-3-methyl-5h,10h-imidazo[2,1-b]quinazoline-2(3h)-one, (R)-6-chloro-3-methyl-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one, Imidazo(2,1-b)quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-, (R)-

ID: 229

InChIKey: BIDZCDUCZHIKMO-VCHYOVAHSA-N
SMILES: C/C(=N\NC1=NC2=CC=CC=C2S1)/C3=CC=C(C=C3)Cl

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 9599957
synonyms found at PubChem are:
SCHEMBL838475, STK666972, AKOS001003898, MCULE-8836018202, A1470/0064857, 2-{(2E)-2-[1-(4-chlorophenyl)ethylidene]hydrazinyl}-1,3-benzothiazole

ID: 230

InChIKey: BITHABUTZRAUGT-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(N(C(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)CC#C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11538542
synonyms found at PubChem are:
MRS 1845, N-Propargylnitrendipene, 544478-19-5, MRS1845, MRS-1845, N-Propylargylnitrendipine, Lopac0_000763, MLS002172491, SCHEMBL8226144, CHEMBL1256776, CTK8E6770, DTXSID50468257, MolPort-003-958-655, HMS2233N15, HMS3373I13, MFCD06798381, AKOS024456822, CCG-204848, LP00763, NCGC00015650-02, NCGC00015650-03, NCGC00015650-04, NCGC00094103-01, NCGC00094103-02, SMR001254114, RT-013955, EU-0100763, MRS 1845, >=95% (HPLC), solid, X4589, M 1692, SR-01000076221, SR-01000076221-1, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(2-propynyl)-3,5-pyridinedicarboxylic acid ethyl, methyl ester

ID: 231

InChIKey: BITQGIOJQWZUPL-PBCQUBLHSA-M
SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 42009
synonyms found at PubChem are:
CEFMETAZOLE SODIUM, 56796-39-5, Cefmetazon, Zefazone, CMZ sodium, CEFMETAZOLE SODIUM SALT, CS 1170 sodium, SKF 83088 sodium, Cefmetazole (sodium), cefmetazone, UNII-37Y9VR4W7A, Zefazone In Plastic Container, CHEBI:3490, U 72791A, Metafar, 37Y9VR4W7A, DSSTox_CID_25590, DSSTox_RID_80985, DSSTox_GSID_45590, Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, U-72791A, CMZ, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-cis)-, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, sodium salt, (6R-cis)-, sodium (6R,7S)-7-(2-(cyanomethylthio)acetamido)-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, C15H16N7NaO5S3, Cefmetazole sodium [USAN:JAN], Sodium cefmetazole, Prestwick_21, NCGC00017120-01, Zefazone (TN), Cefmetazole sodium [USAN:USP:JAN], CAS-56796-39-5, Epitope ID:116656, MLS000028660, SCHEMBL193751, C15H16N7O5S3.Na, CHEMBL1201118, DTXSID5045590, Cefmetazole sodium (JP17/USP), CTK8F8525, AOB5078, MolPort-006-823-792, HMS1570K21, HMS2097K21, HMS2230G19, HMS3260F14, HMS3714K21, 56796-20-4 (Parent), BCP11979, HY-B1257, Tox21_110788, Tox21_500266, MFCD00214260, AKOS025392167, Tox21_110788_1, ACN-045447, API0001892, CCG-220700, CCG-221570, CS-4966, KS-1415, LP00266, NCGC00023016-07, NCGC00093724-01, NCGC00260951-01, AN-40039, SMR000058923, CS-1170; SKF-83088, LS-150047, EU-0100266, FT-0603044, ST51014954, C 6048, C08104, D00911, A831179, Cefmetazole sodium salt, Antibiotic for Culture Media Use Only, (6R-cis)-7-((((Cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt, (7S,7aR)-7-[2-(cyanomethylthio)acetylamino]-7-methoxy-3-[(1-methyl(1,2,3,4-tet raazol-5-ylthio))methyl]-6-oxo-2H-azetidino[2,1-b]1,3-thiazine-4-carboxylic ac id, sodium salt, Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanyl, sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, sodium (6R,7S)-7-[2-(cyanomethylsulfanyl)ethanoylamino]-7-methoxy-3-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanylmethyl]-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, sodium 6beta-{[(cyanomethyl)sulfanyl]acetamido}-6alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}ceph-3-em-4-carboxylate

ID: 232

InChIKey: BIWJNBZANLAXMG-UHFFFAOYSA-N
SMILES: C1C2C(C(C1Cl)Cl)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5993
synonyms found at PubChem are:
chlordane, Chlorindan, Chlordan, Octachlor, Kypchlor, Toxichlor, Belt, Ortho-Klor, Chlor Kil, Technical chlordane, Chlordane, technical, Octachlordane, Chlorotox, Dowchlor, Oktaterr, Starchlor, Topiclor, Sydane, Termex, Intox, Cortilan-neu, Unexan-Koeder, Dichlorochlordene, Octa-Klor, Chlordane-technical, 12789-03-6, Tat Chlor 4, Intox (insecticide), Velsicol 1068, cis-Chlordane, trans-Chlordane, Caswell No. 174E, Chlorodane, Shell sd-5532, RCRA waste number U036, Synklor, CCRIS 854, Octachlorodihydrodicyclopentadiene, CD 68, NCI-C00099, HCS 3260, 57-74-9, Chlordane, technically grade, SD 5532, Chloordaan, 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane, Clordan, Clordano, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene, Aspon-chlordane, Kilex lindane, trans-Chlordan, t-Chlordane, Termi-ded, M 140, M 410, CHEBI:34623, Chlordane , pur, Topichlor 20, Topiclor 20, Clordan [Italian], Intox 8, Chloordaan [Dutch], 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, Caswell No. 174, Chlordane (Technical), Chlordane, technical grade, Latka 1068 [Czech], Octachloro-4,7-methanotetrahydroindane, 4,7-Methanoinden, 1,2,4,5,6,7,8,9-octachloro-3a,4,7,7a-tetrahydro-, CCRIS 127, alpha-Chlordan, HSDB 802, Chlordan, cis-, .alpha.-Chlordan, Photochlordane, Chlortox, Syndane, .alpha.-Chlordane, NSC 8931, OMS 1437, EINECS 200-349-0, EINECS 225-826-0, 1,3,4,7,8,9,10,10-octachlorotricyclo[5.2.1.0(2,6)]dec-8-ene, ENT 25,552-X, ENT 9,932, 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan, EPA Pesticide Chemical Code 058201, ALPHA-CHLORDANE, cis-Photochlordane, UN 2996, BRN 1915474, BRN 3910347, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1.alpha.,2.alpha.,3a.alpha.,4.beta.,7.beta.,7a.alpha.)-, AI3-16398, RCRA waste no. U036, Chlordane (technical grade), Chlordane (analytical grade), Chlordane, alpha & gamma isomers, oindane, c-Chlordane, Chlor kill, EINECS 225-825-5, C orodane, Dow-klor, 1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane, 4,7-Methanoindan, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, Chlordane, liquid, .gamma.-Chlordan, 1,2,4,5,6,7,8,8-Octachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indaan [Dutch], 1,2,4,5,6,7,8,8-Octachlor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indan [German], 1,2,4,5,6,7,8,8-Ottochloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indano [Italian], (1alpha,2beta,3aalpha,4beta,7beta,7aalpha)-1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1.alpha.,2.beta.,3a.alpha.,4.beta.,7.beta.,7a.alpha.)-, 4,7-Methanoindan, 3a-beta,4,7,7a-beta-tetrahydro-1-beta,2-alpha,4-alpha,5,6,7-alpha,8,8-octachloro-, 5103-74-2, AI3-16397, Chlordane (technical mixture and metabolites), Compound K (FDA), alpha-, gamma-Chlordane, AC1L1LKC, AC1Q3FIS, D01MFT, DSSTox_CID_28117, DSSTox_RID_77241, DSSTox_GSID_23954, SCHEMBL75811, Chlordane (avg cis-,trans-), Octachlorohexahydromethanoindene, CHEMBL196537, GTPL2831, Octach lorohexahydromethanoindene, 4,7-Methanoindan, 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-, DTXSID7020267, CTK8F8589, NSC8931, BIWJNBZANLAXMG-UHFFFAOYSA-N, sd 553 2, CD-68, ENT-25,552-x, (1alpha,2alpha,3aalpha,4beta,7beta,7aalpha)-1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1alpha,2alpha,3a alpha,4beta,7beta,7a alpha)-, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1alpha,2beta,3a alpha,4beta,7beta,7a alpha)-, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1R,2R,3aS,4S,7R,7aS)-rel-, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1R,2S,3aS,4S,7R,7aS)-rel, 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, (1R,2S,3aS,4S,7R,7aS)-rel-, 4,7-Methanoindan, 1-alpha,2-alpha,4-beta,5,6,7-beta,8,8-octachloro-3a-alpha,4,7,7a-alpha-tetrahydro-, 4,7-Methanoindan, 1.alpha.,2.alpha.,4.beta.,5,6,7.beta.,8,8-octachloro-3a.alpha.,4,7,7a.alpha.-tetrahydro-, ENT-9932, HCS-3260, NSC-8931, Chlordane (alpha and gamma isomers), Tox21_200290, BDBM50410490, ENT-9,932, LS-233, LS-715, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-4,7-Methano-1H-indene, NCGC00091433-01, NCGC00091433-03, NCGC00257844-01, 33442-85-2, LS-90933, LS-90941, CAS-12789-03-6, TL8003712, FT-0602992, C14176, Chlordane (technical) 10 microg/mL in Cyclohexane, Chlordane (technical) 2000 ng/microl in Methanol, J-005552, WLN: L C555 A IUTJ AG AG BG DG EG HG IG JG, CHLORDANE (TECHNICAL GRADE) (SEE ALSO 57-74-9), 4, 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-, CHLORDANE (ANALYTICAL GRADE) (SEE ALSO 12789-03-6), 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetra-hydro-4,7-methan-, 1,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindan, 4, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-, Chlordane (technical, RM, ISO Guide 34) 1000 mg/L in n-Hexane, 1 ,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetra-hydro-4,7-methan-, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindane, 1,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane, 1,4,5,6,7,8,8-Octachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indaan, 1,4,5,6,7,8,8-Octachlor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indan, 1,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan, 1,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene, 1,4,5,6,7,8,8-Octachloro-3a,4,7,7a-hexahydro-4,7-methylene indane, 1,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane, 1,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane, 1,4,5,6,7,8,8-Ottochloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indano, (4S,7R)-1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene, 1,2,4,5,6,7,8,8-octa-8,8-octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindan, 1-Exo,2-endo,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene, 1,5:2,4-Dimethanopentalene, 1,2,5,6,6,6a,7,8-octachlorooctahydro-, (1alpha,2alpha,3aalpha,4beta,5alpha,6aalpha,7R*,8R*)-, 52002-35-4

ID: 233

InChIKey: BIXJFIJYBLJTMK-MEBBXXQBSA-N
SMILES: CN1C[C@@H](C=C2[C@H]1CC3=CNC4=CC=CC2=C34)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 14987
synonyms found at PubChem are:
lysergol, 602-85-7, Lysergole, UNII-NTR684Z1AZ, NTR684Z1AZ, CHEMBL39947, CHEBI:60528, (6-methyl-9,10-didehydroergolin-8beta-yl)methanol, 9,10-Didehydro-6-methyl-8-hydroxymethylergoline, (7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanol, [(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]methanol, LOL, (7-Methyl-4,6,6a,7,8,9-hexahydro-indolo(4,3-fg)quinolin-9-yl)-methanol, Prestwick_308, Prestwick0_000454, Prestwick1_000454, Prestwick2_000454, Prestwick3_000454, 9,10-didehydro-6-methylergoline-8b-methanol, D01APL, AC1L24WZ, BSPBio_000528, GTPL123, cid_14987, MLS001049075, DivK1c_000515, SCHEMBL178071, SPBio_002467, AC1Q77R9, BPBio1_000582, MEGxp0_001732, ACon0_000797, ACon1_000057, HMS501J17, KBio1_000515, ((6aR,9R)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl)methanol, BIXJFIJYBLJTMK-MEBBXXQBSA-N, MolPort-001-740-040, NINDS_000515, HMS1569K10, HMS2096K10, HMS2271M04, TNP00316, ZINC3983953, BDBM50016479, AKOS030490884, MCULE-2342911271, Phytochem 12: 2435 (1973), 9,10-didehydro-6-methylergoline-8beta, IDI1_000515, SMP1_000185, NCGC00017367-01, AS-18087, CC-30100, SMR000386913, DB-053583, FT-0082603, FT-0621597, W0044, 9,10-Didehydro-6-methylergoline-8|A-methanol, 9,10-Didehydro-8-hydroxymethyl-6-methyl-ergoline, C-15770, SR-01000758923, SR-01000758923-3, BRD-K27871032-001-02-6, BRD-K27871032-001-04-2, 1413-67-8

ID: 234

InChIKey: BIXYYZIIJIXVFW-UUOKFMHZSA-N
SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(N=C2N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 8974
synonyms found at PubChem are:
2-Chloroadenosine, 146-77-0, 6-Amino-2-chloropurine riboside, Cl-Ado, ADENOSINE, 2-CHLORO-, 2-Chloroadenosinehemihydrate, UNII-7W7ZUG45G8, 2-Chloro Adenosine, 2Cl-Ado, CADO, (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, EINECS 205-678-3, NSC 36896, 2 ClAdo, BRN 0043957, MLS000028365, 7W7ZUG45G8, CHEMBL285819, 2-CADO, BIXYYZIIJIXVFW-UUOKFMHZSA-N, SMR000058612, 103090-47-7, 2 Chloroadenosine, (2R,3R,4S,5R)-2-(6-amino-2-chloro-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, (2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 5-Chloroformycin A, 2-Chloroado, 2-CI Adenosine, 2-chloro-adenosine, 2-chloro[3h]adenosine, PubChem14159, Opera_ID_460, D0C2UJ, AC1L1S1S, REGID_for_CID_8974, 2-Cl-Ado / 2-CADO, GTPL372, 4-26-00-03725 (Beilstein Handbook Reference), KSC177Q0T, MLS001424176, MLS002153284, SCHEMBL104094, Jsp002712, 2-(6-Amino-2-chloro-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol, CTK0H7809, CHEBI:125640, MolPort-003-928-215, HMS2051B22, HMS2235K11, KS-00000NB1, ZINC3875976, ANW-47074, BDBM50009525, MFCD00005734, PDSP1_000569, PDSP1_000999, PDSP1_001209, PDSP2_000567, PDSP2_000983, PDSP2_001193, AKOS015896917, AKOS015995296, AM83941, CCG-101063, CS-W008344, NC00313, RL01849, RTX-011768, NCGC00021540-03, NCGC00021540-04, NCGC00021540-05, NCGC00021540-06, AJ-46476, AK-49403, AN-14534, AS-12085, BR-49403, CC-10171, CJ-11031, CPD000058612, KB-44588, LS-15106, SAM001246886, 2-Chloro-9-(beta-D-ribofuranosyl)adenine, AB0066073, AB1007209, AX8008046, DB-005234, ST2409923, TL8001029, FT-0601308, FT-0689532, M-1270, 146C770, C-18836, 2-[6-Amino-2-(2-cyclopentyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

ID: 235

InChIKey: BJIPVHLRWSDKOS-UHFFFAOYSA-N
SMILES: C1CC2=C3C(=CC=C2)N(S(=O)(=O)N3C1)CCN4CCC(=CC4)C5=CNC6=C5C=CC(=C6)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4605800
synonyms found at PubChem are:
LY-367,265, LY-367265, CHEMBL1079460, 1-[2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]ethyl]-5,6-dihydro-1H,4H-[1,2,5]thiadiazolo[4.3.2-ij]quinoline-2,2-dioxide, AC1NDRET, NCGC00015600-01, LY367265, LY 367265, Lopac-L-2411, Lopac0_000648, MLS002172448, SCHEMBL7793847, HMS2232M07, HMS3262A17, HMS3373J15, Tox21_500648, BDBM50313283, ZINC52569996, CCG-204735, LP00648, NCGC00015600-02, NCGC00015600-03, NCGC00015600-04, NCGC00094014-01, NCGC00094014-02, NCGC00261333-01, 1-(2-(4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl)ethyl)-5,6-dihydro1H,4H-(1,2,5)thiadiazolo(4.3.2-ij)quinoline-2,2-dioxide, SMR001254083, EU-0100648, L 2411, L020228, SR-01000075958, SR-01000075958-1, 1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-4,5-dihydro-1H,3H-2-thia-1,2a-diaza-acenaphthylene 2,2-dioxide, 1H,4H-(1,2,5)Thiadiazolo(4,3,2-ij)quinoline, 1-(2-(4-(6-fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl)ethyl)-5,6-dihydro-, 2,2-dioxide, 210751-39-6

ID: 236

InChIKey: BJORNXNYWNIWEY-UHFFFAOYSA-N
SMILES: C1CC(C2=CC=CC=C2C1)C3=NCCN3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10648
synonyms found at PubChem are:
Tetrahydrozoline hydrochloride, 522-48-5, Tetrahydrozoline HCl, Tetryzoline hydrochloride, Tyzine, Vasopos, Murine Plus, Tyzanol hydrochloride, 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride, Tetrahydrozoline (hydrochloride), EINECS 208-329-3, AI3-50165, MLS000069739, 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, monohydrochloride, 2-tetralin-1-yl-4,5-dihydro-1H-imidazole hydrochloride, SMR000058219, 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline hydrochloride, 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline monohydrochloride, DSSTox_CID_25316, DSSTox_RID_80797, DSSTox_GSID_45316, Tetrahydrozoline nitrate, 2-IMIDAZOLINE, 2-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)-, HYDROCHLORIDE, 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1), SR-01000000161, Tetryzoline HCl, visine hydrochloride, Tetrahydrozoline hydrochloride [USP], Prestwick_1025, Tyzine (TN), 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole;hydrochloride, Tetrahydrozoline hydrochloride [USAN:BAN], AC1L1VND, Tetryzolini hydrochloridum, Opera_ID_1724, NCGC00016485-01, CAS-522-48-5, SCHEMBL25702, MLS000079025, MLS001146954, MLS002222291, MLS002548902, 84-22-0 (Parent), SPECTRUM1500567, CHEMBL1200413, DTXSID7045316, HY-B0556A, MolPort-000-720-037, HMS1570K17, HMS1921C21, Pharmakon1600-01500567, BCP15857, Tox21_110450, Tox21_501137, AN-165, CCG-39268, MFCD00058029, NSC757339, AKOS015899540, Tox21_110450_1, AC-1110, CS-2666, LP01137, MCULE-6434802156, NC00484, NSC-757339, Tetrahydrozoline hydrochloride, >=98%, KS-00000N92, NCGC00016018-10, NCGC00094403-01, NCGC00094403-02, NCGC00094403-03, NCGC00094403-04, NCGC00094403-05, NCGC00261822-01, AS-15973, BC209867, CPD000058219, LS-79684, R615, SAM002264650, ST013854, Tetrahydrozoline hydrochloride (JAN/USP), AB0018230, 4CH-023705, EU-0101137, FT-0675067, S4043, ST24050142, VU0239726-5, D01023, K-9553, T 4264, 522T485, Q-201816, SR-01000000161-2, SR-01000000161-8, I14-11410, Z1695906783, 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-,monohydrochloride, 2-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HCL, 2-[(1RS)-1,2,3,4-Tetrahydronaphthalen-1-yl]-4,5-dihydro-1H-imidazole hydrochloride, Tetrahydrozoline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Tetrahydrozoline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 124638-40-0, 33067-94-6, 8059-87-8, Tetrahydrozoline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, AC1LCW9I, hydron; 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole; chloride

ID: 237

InChIKey: BJPJNTKRKALCPP-UHFFFAOYSA-N
SMILES: CCCNC(C)C(=O)NC1=CC=CC=C1C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 92163
synonyms found at PubChem are:
Prilocaine hydrochloride, 1786-81-8, Propitocaine hydrochloride, Prilocaine HCl, Xylonest, Prilocaine chloride, Citanest hydrochloride, Citanest plain, N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride, Prilocaine (hydrochloride), 2-(Propylamino)-, 2-(Propylamino)-o-propionotoluidide hydrochloride, L-67, EINECS 217-244-0, MLS000069690, 2-(Propylamino)-N-(o-tolyl)propanamide hydrochloride, 2-(Propylamino)-o-propionotoluidide monohydrochloride, alpha-Propylamine-2-methyl-propionanilide hydrochloride, 878791-35-6, o-Propionotoluidide, 2-(propylamino)-, monohydrochloride, Propitocaine HCl, SMR000058506, Citanest (TN), Propanamide, N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride, DSSTox_CID_11956, DSSTox_RID_78897, DSSTox_GSID_31956, Q-201619, N-(2-methylphenyl)-2-(propylamino)propanamide;hydrochloride, CHEBI:32053, SR-01000076094, Prilocaine hydrochloride [USAN], Prilocaine, HCl, Prestwick_616, Prilocaine hydrochloride [USAN:USP], L 67 Hydrochloride, Propitocainehydrochloride, Opera_ID_480, AC1L3NJV, NCGC00016594-01, CAS-1786-81-8, MLS002222230, MLS002548864, ARONIS24439, SCHEMBL330180, SPECTRUM1503270, Prilocaine hydrochloride (USP), CHEMBL1200586, DTXSID2031956, CTK8G2574, HY-B0137A, Propitocaine hydrochloride (JAN), BBC/603, EBD2408, MolPort-003-666-478, HMS1568H19, HMS1922O15, Pharmakon1600-01503270, Prilocaine HCl (Propitocaine HCl), ACT04757, BCP22337, ZX-AS004804, Tox21_110513, Tox21_501005, BG0296, CCG-39327, DT1296, FC1266, GP0348, MFCD00079279, NSC758432, AKOS015895106, Tox21_110513_1, AC-2099, API0003927, CS-1930, KS-5024, LP01005, LS-2121, MCULE-7993425453, NC00474, NSC-758432, NCGC00015860-06, NCGC00094299-01, NCGC00094299-02, NCGC00094299-03, NCGC00094299-04, NCGC00094299-05, NCGC00261690-01, AN-14287, BC209185, CPD000058506, Prilocaine hydrochloride, >=98% (TLC), SAM002264640, SC-22683, BCP0726000006, AB0005494, AB1004860, AX8040365, LS-119349, LS-119350, LS-119351, EU-0101005, FT-0633840, P2038, ST24049036, ST51015112, D01243, EN300-188472, J10292, M-1534, P 9547, 2-(Propylamino)-m-propionotoluidide Hydrochloride, 2-(propylamino)-N-o-tolylpropanamide hydrochloride, 786P818, A812391, I06-0422, SR-01000076094-1, SR-01000076094-6, 2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride, N-(2-methylphenyl)-N2-propylalaninamide hydrochloride, N-(o-tolyl)-2-(propylamino)propanamide hydrochloride, N-(2-methylphenyl)-2-(propylamino)propanamide, chloride, N-(3-Methylphenyl)-2-(propylamino)propanamide Hydrochloride, PRILOCAINE HYDROCHLORIDE (PRILOCAINE (721-50-6)), Prilocaine hydrochloride, meets USP testing specifications, N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride, Prilocaine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Prilocaine for peak identification, European Pharmacopoeia (EP) Reference Standard, Prilocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 2-(Propylamino)-o-propionotoluidide hydrochloride; N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride, N-(2-methylphenyl)-N(2)-propylalaninamide hydrochloride, N-{1-[(2-methylphenyl)amino]-1-oxopropan-2-yl}propan-1-aminium chloride, 2-(Propylamino)-O-Propionotoluididmonohydrochloride, AKOS026749949

ID: 238

InChIKey: BJPSSVHNEGMBDQ-NUZBWSBOSA-N
SMILES: C[C@H]1[C@@H]2CCC(=C3[C@@H]([C@H]2OC1=O)C(=CC3=O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 167683
synonyms found at PubChem are:
Leucodin, Desacetoxymatricarin, Leucomisine, Leukodin, Axillin, Deacetoxymatricarin, Leucodine, Leukomisin, 17946-87-1, Desacetoxymatricarine, (+)-Leukodin, Leukodin, (+)-, Matricarin, deacetoxy-, UNII-1G2W00IRUI, 1G2W00IRUI, CHEBI:4441, Deacetoxy matricarin, (3s,3as,9as,9bs)-3,6,9-trimethyl-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione, Guaia-1(10),3-dien-12-oic acid, 6-alpha-hydroxy-2-oxo-, gamma-lactone, (11S)-, 68247-35-8, Azuleno(4,5-b)furan-2,7-dione, 3,3a,4,5,9a,9b-hexahydro-3,6,9-trimethyl-, (3S-(3alpha,3aalpha,9aalpha,9bbeta))-, Azuleno(4,5-b)furan-2,7-dione, 3,3a,4,5,9a,9b-hexahydro-3,6,9-trimethyl-,(3S,3aS,9aS,9bS)-, SMR000445670, Leucomisin, Spectrum_001968, SpecPlus_000876, Prestwick0_001084, Prestwick1_001084, Prestwick2_001084, Prestwick3_001084, Spectrum2_001657, Spectrum3_001631, Spectrum4_001825, Spectrum5_000589, AC1L50EE, BSPBio_001128, BSPBio_003321, KBioGR_002495, KBioSS_002530, MLS000728557, MLS002154146, DivK1c_006972, SPBio_001813, SPBio_003024, AC1Q6O26, BPBio1_001242, CHEMBL517040, CTK5C7607, KBio1_001916, KBio2_002522, KBio2_005090, KBio2_007658, KBio3_002541, DTXSID20170810, BJPSSVHNEGMBDQ-NUZBWSBOSA-N, MolPort-002-507-193, HMS1571I10, HMS2098I10, HMS2221B10, ZINC5534507, CCG-38769, AKOS015969701, NCGC00163587-02, NCGC00163587-03, LS-73187, AB00514036, C09394, J-011454, BRD-K96119599-001-05-4

ID: 239

InChIKey: BJRNKVDFDLYUGJ-RMPHRYRLSA-N
SMILES: C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 440936
synonyms found at PubChem are:
arbutin, 497-76-7, Uvasol, p-Arbutin, Ursin, beta-Arbutin, 4-Hydroxyphenyl beta-D-glucopyranoside, Arbutoside, Arbutine, Arbutyne, Ursi, p-Hydroxyphenyl beta-D-glucoside, p-Hydroxyphenyl beta-D-glucopyranoside, UNII-C5INA23HXF, Hydroquinone-O-beta-D-glucopyranoside, Hydroquinone |A-D-glucopyranoside, C5INA23HXF, 4-Hydroxyphenyl-beta-D-glucopyranoside, CHEMBL232202, CHEBI:18305, Hydroquinone beta-D-glucopyranoside, hydroquinone O-beta-D-glucopyranoside, 4-Hydroxyphenyl-.beta.-D-glucopyranoside, Hydroquinone-beta-D-glucopyranoside, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol, DSSTox_CID_20152, DSSTox_RID_79450, DSSTox_GSID_40152, C12H16O7, Hydroquinone glucose, NSC 4036, EINECS 207-850-3, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol, (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol, BRN 0089673, CAS-497-76-7, Uva, SR-05000002157, CCRIS 9273, HSDB 7661, NCGC00095599-01, beta-D-Glucopyranoside, 4-hydroxyphenyl, Spectrum_000786, SpecPlus_000314, Arbutin, >=98%, Prestwick3_001026, Spectrum2_000662, Spectrum3_001233, Spectrum4_001474, Spectrum5_000147, bmse000365, Arbutin (Uva, p-Arbutin), Arbutin, analytical standard, SCHEMBL36351, Arbutin - Uva - p-Arbutin, BSPBio_001211, BSPBio_002706, Hydroquinone-beta-D-glucoside, KBioGR_002047, KBioSS_001266, SPECTRUM300539, 5-17-07-00110 (Beilstein Handbook Reference), MLS002207046, DivK1c_006410, SPBio_000723, AC1L9A87, BPBio1_001333, MEGxp0_001504, DTXSID7040152, KBio1_001354, KBio2_001266, KBio2_003834, KBio2_006402, KBio3_002206, hydroquinone O--D-glucopyranoside, BJRNKVDFDLYUGJ-RMPHRYRLSA-N, MolPort-001-742-322, HMS2098M13, HMS3715M13, ZINC518554, HY-N0192, 4-Hydroxyphenyl-beta-glucopyranoside, Tox21_111509, Tox21_302428, BDBM50219502, CA0139, CCG-38565, DT1742, GC0919, MFCD00016915, s2263, AKOS015965305, Tox21_111509_1, CS-3084, DB11217, KS-5252, RP29659, SDCCGMLS-0066538.P001, KS-00000L08, SMP1_000028, NCGC00166076-02, NCGC00166076-03, NCGC00166076-04, NCGC00166076-07, NCGC00255705-01, AC-20183, SMR001233417, TR-012619, A0522, AB00443586, FT-0622464, N1714, A-9320, C06186, beta-D-Glucopyranoside, 4-hydroxyphenyl- (9CI), 497A767, Arbutin, primary pharmaceutical reference standard, Arbutin pound>>4-hydroxyphenyl-beta-d-glucopyranosid, SR-05000002157-2, SR-05000002157-4, alpha-Arbutin; 4-Hydroquinone-alpha-D-glucopyranoside, Arbutin, European Pharmacopoeia (EP) Reference Standard, 4E19B706-2013-4401-A1FC-A154DADF42B4, (2S,3R,4S,5S,6R)-2-(4-hydroxyphenoxy)-6-methylol-tetrahydropyran-3,4,5-triol, 30373-96-7, 39464-18-1

ID: 240

InChIKey: BKFGETNNNHDCBQ-UHFFFAOYSA-N
SMILES: CCOC1=CC=C(C=C1)C(=O)C2=CC(=C(C(=C2O)OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3985760
synonyms found at PubChem are:
KBio3_001176, Spectrum_000360, SpecPlus_000739, AC1N1REL, Spectrum2_000163, Spectrum3_000258, Spectrum4_001553, Spectrum5_000146, BSPBio_001676, KBioGR_002046, KBioSS_000840, DivK1c_006835, SCHEMBL720116, SPBio_000025, KBio1_001779, KBio2_000840, KBio2_003408, KBio2_005976, CCG-40006, NCGC00179097-01, SR-05000002579, 2,5-dihydroxy-3,4-dimethoxy-4'-ethoxybenzophenone, SR-05000002579-1, 2,4-DIHYDROXY-3,4-DIMETHOXY-4'-ETHOXYBENZOPHENONE, (2,5-dihydroxy-3,4-dimethoxyphenyl)-(4-ethoxyphenyl)methanone

ID: 241

InChIKey: BKMMTJMQCTUHRP-VKHMYHEASA-N
SMILES: C[C@@H](CO)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 80307
synonyms found at PubChem are:
L-Alaninol, 2749-11-3, (S)-(+)-2-Amino-1-propanol, (S)-2-Aminopropan-1-ol, (2S)-2-aminopropan-1-ol, H-Alaninol, Alaninol, (S)-2-amino-1-propanol, (+)-2-Aminopropan-1-ol, 2-Aminopropanol, (+)-, UNII-V403GH89L1, S-(+)-2-Amino-1-propanol, CHEBI:78502, V403GH89L1, 1-Propanol, 2-amino-, (2S)-, L-2-aminopropan-1-ol, Ala-ol, (S)-alaninol, 2A1, L-(+)Alaninol, PubChem5710, L-ALANILOL, (S)-2-amino propanol, (S)-2-amino-propanol, L-Alaninol; H-Ala-ol, L-Alaniol (S)-(+)-2-Amino-1-Propanol, H-ALA-OL, (S)-2-aminopropan-1ol, H-L-ALA-OL, L-(+)-ALANINOL, AC1L2Z6S, AC1Q29JF, AC1Q77PT, L-2-AMINO-PROPANOL, (5)-2-aminopropan-1-ol, (S)-2-aminopropane-1-ol, (2S)-2-amino-1-propanol, (S)-2-amino-propan-1-ol, 2-(S)-amino-propan-1-ol, (25)-2-amino-1-propanol, KSC201Q8F, (S)-1-hydroxymethylethylamine, CHEMBL1229871, CTK1A1882, (2R)-2-Amino-1-hydroxypropane, (S)-(+) 2-amino-1-propanol, (S)-(+)-2 amino-1-propanol, (S)-(+)-2-aminopropan-1-ol, (S)-(-)-2-amino-1-propanol, BKMMTJMQCTUHRP-VKHMYHEASA-N, MolPort-001-756-366, MolPort-044-811-390, (2S)-(+)-1-Aminopropan-2-ol, (2S)-(+)-2-aminopropan-1-ol, ACT03197, CS-B1303, ZINC1576782, EINECS 220-388-7, ANW-13770, CA0153, MFCD00064412, AKOS000302243, AC-1565, LS30252, MCULE-5424195678, RP18346, RTC-066857, KS-000000P5, (S)-(+)-2-Amino-1-propanol, 98%, AC-24154, AJ-27334, AS-12033, BC678138, KB-74560, KB-78086, SC-03066, AB1004159, DB-047233, ST2414602, TC-066857, EN300-86282, 49A113, C-5053, M03438, F0001-2971, UNII-E8V71RA4B5 component BKMMTJMQCTUHRP-VKHMYHEASA-N

ID: 242

InChIKey: BKPRVQDIOGQWTG-FKXFVUDVSA-N
SMILES: C1[C@H]([C@@H]1N)C2=CC=CC=C2.C1[C@H]([C@@H]1N)C2=CC=CC=C2.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 25267092
synonyms found at PubChem are:
Tranylcypromine hemisulfate, 13492-01-8, Tranylcypromine sulfate, TRANS-2-PHENYLCYCLOPROPYLAMINE HEMISULFATE SALT, (1R,2S)-2-phenylcyclopropan-1-amine;sulfuric acid, 1-amino-2-phenylcyclopropanesulfate, Tranylcypromine sulfate [USAN:USP], AKOS028113138, API0009012, [(1R,2S)-2-phenylcyclopropyl]ammonium, [(1S,2R)-2-phenylcyclopropyl]ammonium, AS-16857, trans-2-phenylcyclopropylamine HEMISULFATE, FT-0082080, (1R,2S)-2-phenylcyclopropanamine hemisulfate, (+-)-trans-2-phenylcyclopropylaminesulfate(2:1), C-20989, trans-2-phenyl-cyclo-propyl-amine hemisulfate salt, UNII-7ZAT6ES870 component BKPRVQDIOGQWTG-FKXFVUDVSA-N, 2-phenyl-cyclopropanamintrans-(+-)-cyclopropanaminsulfate(2:1), Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-, sulfate (2:1), 2-phenyl-cyclopropylaminsulfate,trans-(+-)-cyclopropylamin(2:1), 1949-18-4, 7081-36-9

ID: 243

InChIKey: BKQOOFNCLBQRBE-UHFFFAOYSA-N
SMILES: CCC1=CC=C(C=C1)NC2=NC3=CC=CC=C3C(=C2)C

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 672890
synonyms found at PubChem are:
N-(4-ethylphenyl)-4-methylquinolin-2-amine, AC1LDR0E, Oprea1_705013, SCHEMBL837756, ZINC34772, MolPort-002-562-123, STK762924, AKOS001622833, MCULE-7925097098, ST050514, KB-309009, (4-ethylphenyl)(4-methyl(2-quinolyl))amine, N-(4-ethylphenyl)-N-(4-methyl-2-quinolyl)amine, SR-01000450823, SR-01000450823-1, A2274/0095834

ID: 244

InChIKey: BKRGVLQUQGGVSM-KBXCAEBGSA-N
SMILES: CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 28864
synonyms found at PubChem are:
LISURIDE, Lysuride, Lisurida, Lisuridum, 18016-80-3, Lisuridum [INN-Latin], Lisurida [INN-Spanish], Lisuride [INN], Methylergol Carbamide, lisuride maleate, Lysurid, Lisurid, Lysuride Hydrogen Maleate, Lisuride Maleate (1:1), UNII-E0QN3D755O, Lisuride (INN), Lisuride (S)(-), EINECS 241-925-1, N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea, CHEMBL157138, E0QN3D755O, C20H26N4O, CHEBI:51164, 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea, 3-(9,10-Didehydro-6-methylergolin-8alpha-yl)-1,1-diethylurea, Urea, N'-((8alpha)-9,10-didehydro-6-methylergolin-8-yl)-N,N-diethyl-, Dopergin, Lisuride [INN:BAN], mesorgydine, Dopergine (TN), Dipergon (TN), Dopergin (TN), Prolacam (TN), (+)-lisuride, 140387-89-9, lisuride, (S), Prestwick_525, Cuvalit (TN), Revanil (TN), Arolac (TN), Lysenyl Forte (TN), Prestwick0_000106, Prestwick1_000106, Prestwick2_000106, Prestwick3_000106, D0X7KB, GTPL43, methylergol carbamide maleate, Lopac0_000751, SCHEMBL43950, BSPBio_000092, SPBio_002031, AC1L1G87, BPBio1_000102, CTK0H5613, BKRGVLQUQGGVSM-KBXCAEBGSA-N, HMS1568E14, ZINC3831001, BDBM50056445, AKOS024457950, CCG-204836, DB00589, NCGC00179663-02, 19875-60-6 (maleate (1:1)), LS-159312, FT-0670825, D08132, 118272-EP2275420A1, 118272-EP2280008A2, 118272-EP2281559A1, 118272-EP2298764A1, 118272-EP2298765A1, 1,1-diethyl-3-(9,10-didehydro-6-methyl-8alpha-ergolinyl)urea, 3-(9,10-didehydro-6-methyl-8alpha-ergolinyl)-1,1-diethylurea, N''-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea, N,N-diethyl-N'-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea, Urea, N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-, 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0;{2,7}.0;{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea, 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea, H8G

ID: 245

InChIKey: BKXVVCILCIUCLG-UHFFFAOYSA-N
SMILES: C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54900
synonyms found at PubChem are:
RALOXIFENE HYDROCHLORIDE, 82640-04-8, Raloxifene Hcl, Evista, Keoxifene hydrochloride, (6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone hydrochloride, Raloxifene (hydrochloride), LY 156758, UNII-4F86W47BR6, CHEBI:50740, Evista (Raloxifene Hydrochloride), 4F86W47BR6, 6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride, C28H28ClNO4S, DSSTox_CID_14181, DSSTox_RID_79119, DSSTox_GSID_34181, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride, 2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride, LY-156758, 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol hydrochloride, Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride, SMR000058508, NCGC00015889-05, CAS-82640-04-8, Loxifen, Optruma, SR-01000076102, Keoxifene HCl, CDT-Raloxifene, Raloxifene hydrochloride [USAN], [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride, Evista (TN), Prestwick_1035, Raloxifene hydrochloride [USAN:USP], Methanone, hydrochloride, AC1L1HY9, AC1Q3F5K, C28H27NO4S.HCl, Study Drug, raloxifene HCI, CHEMBL1116, SCHEMBL19077, MLS000859902, MLS001332533, MLS001332534, MLS002222293, Raloxifene hydrochloride, solid, Evista, Raloxifene hydrochloride, DTXSID1034181, CTK7J9865, KS-00000JPS, LY-139481 HCl, BKXVVCILCIUCLG-UHFFFAOYSA-N, HMS1570N05, Pharmakon1600-01505622, 84449-90-1 (Parent), BCP05713, Raloxifene hydrochloride (JAN/USP), Tox21_110255, Tox21_302369, Tox21_501051, ANW-54600, HY-13738A, MFCD01938233, NSC706725, NSC759285, s1227, AKOS008131940, Tox21_110255_1, AC-8390, AN-8061, CCG-213497, CS-1775, DS-2162, KS-1102, LP01051, MCULE-7336063262, NC00665, NSC-706725, NSC-759285, RP17875, VA11647, NCGC00015889-03, NCGC00015889-11, NCGC00092353-01, NCGC00092353-03, NCGC00094334-01, NCGC00094334-02, NCGC00255153-01, NCGC00261736-01, 4CA-1076, BC209548, CPD000058508, LS-91271, LY156758, SAM002548975, SC-20043, AB0020647, TC-063566, EU-0101051, FT-0630912, R0109, ST24020666, V1611, EN300-52517, D02217, J90021, M-8965, R 1402, 68523-EP2270008A1, 68523-EP2292617A1, 68523-EP2298768A1, 68523-EP2308855A1, 640R048, I06-1061, I14-1208, Q-201656, SR-01000076102-2, SR-01000076102-9, Raloxifene hydrochloride, European Pharmacopoeia (EP) Reference Standard, Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Raloxifene hydrochloride, United States Pharmacopeia (USP) Reference Standard, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone hydrochloride, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone hydrochloride, [6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone Hydrochloride, [6-hydroxy-2-(4-hydroxyphenyl)benzothiophen-3-yl]-[4-[2-(1-piperidyl)ethoxy]phenyl]methanone hydrochloride, [6-hydroxy-2[4-hydroxyphenyl)benzo [b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride, [6-hydroxy-2[4-hydroxyphenyl)benzo [b]thien3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride, [6-hydroxy-2[4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride, 1-[2-(4-{[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]carbonyl}phenoxy)ethyl]piperidinium chloride, 6-hydroxy-2-(4-hydroxyphenyl)-3-[ 4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene, hydrochloride, 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]-thiophene hydrochloride, 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]thiophene hydrochloride, 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl 4-[2-(1-piperidinyl)ethoxy]phenyl methanone hydrochloride, 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl 4-[2-(1-piperidinyl)ethoxy]phenyl ketone hydrochloride, Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl) (4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride, Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1), Raloxifene hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard, MLS001304731, HMS2233M16, HMS3372E10, AKOS015960340, SMR000752510, AKOS026750144, SCHEMBL19287207

ID: 246

InChIKey: BKYKPTRYDKTTJY-UHFFFAOYSA-N
SMILES: C1CCC(C1)CC2NC3=CC(=C(C=C3S(=O)(=O)N2)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2904
synonyms found at PubChem are:
cyclopenthiazide, Cyclomethiazide, 742-20-1, Cyclometiazid, Cyclopentiazid, Navidreks, Navidrex, Benesal, Salimed, Salimid, Ultra-Minzil, Salurilo-C, Navidrix, Tsiklometiazid, Ciba 8341-Su, SU 8341, Su-8341, 3-Cyclopentylmethyl hydrochlorothiazide deriv, NSC 107679, UNII-866GEV195O, UNII-T7817XC41U, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, MLS000737270, 866GEV195O, T7817XC41U, NSC107679, NSC-107679, DSSTox_CID_2868, DSSTox_RID_76765, DSSTox_GSID_22868, W-104425, Ciclopentiazida, Ciclopentiazide, Cyclopenthiazidum, benesal(van), 6-Chloro-3-cyclopentylmethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-Dioxide, 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, NCGC00016534-01, 8341-Su, Navidrex (TN), CAS-742-20-1, Cyclopenthiazide,(S), (+)-Cyclopenthiazide, (-)-Cyclopenthiazide, AC1L1EQH, Cyclopenthiazide, (+)-, Cyclopenthiazide, (-)-, Prestwick0_000994, Prestwick1_000994, Prestwick2_000994, Prestwick3_000994, AC1Q6TQ3, SCHEMBL49142, BSPBio_001087, SPBio_002978, BPBio1_001197, GTPL7899, Tsiklometiazid (cyclomethiazide), CHEMBL1373254, DTXSID4022868, CHEBI:91686, BKYKPTRYDKTTJY-UHFFFAOYSA-N, Cyclopenthiazide (JAN/USAN/INN), HMS1571G09, HMS2098G09, HMS2886L05, HMS3715G09, BCP24493, Tox21_110481, 3-Cyclopentylmethylhydrochlorothiazide, AKOS024462515, Tox21_110481_1, API0005912, CCG-220994, DB13532, NCGC00179312-03, AN-47430, AT-14650, SMR000528497, AB00513990, FT-0665381, D02061, 742C201, SR-01000776288, WLN: T66 BSWM EM DHJ HG ISZW D1- AL5TJ, SR-01000776288-2, BRD-A41250306-001-03-4, 6-Chloro-3-(cyclopentylmethyl)-3,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, (+)-, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, (-)-, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-,1,1-dioxide, 6-chloro-3-(cyclopentylmethyl)-1,1-diketo-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 96782-85-3, 96783-05-0, 96783-06-1

ID: 247

InChIKey: BLFLLBZGZJTVJG-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=CC=C(C=C1)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2337
synonyms found at PubChem are:
benzocaine, Ethyl 4-aminobenzoate, 94-09-7, Ethyl aminobenzoate, Ethyl p-aminobenzoate, Americaine, Anesthesin, Anaesthesin, Ethoform, Norcaine, Orthesin, Parathesin, Amben ethyl ester, p-Carbethoxyaniline, 4-Aminobenzoic acid ethyl ester, Anaesthin, Anestezin, Anesthesine, Anesthone, Dermoplast, Hurricaine, Identhesin, Parathesine, Keloform, Norcain, Topcaine, Anaesthan-syngala, Ora-jel, Solarcaine, Solu H, p-Ethoxycarboxylic aniline, 4-Carbethoxyaniline, Baby Anbesol, Benzocainum, p-(Ethoxycarbonyl)aniline, Ethyl p-aminophenylcarboxylate, Benzoic acid, 4-amino-, ethyl ester, Benzocaina, 4-(Ethoxycarbonyl)aniline, p-Aminobenzoic acid ethyl ester, Anaesthesinum, Aethoform, Ethoforme, Norcainum, Ethyl PABA, Ethylis aminobenzoas, Anestezin [Russian], Chloraseptic, Bensokain, Otocain, ETHYL4-AMINOBENZOATE, Outgro, 4-Aminobenzoic acid, ethyl ester, Benzocaine Formate, Aethylium paraminobenzoicum, Benzocainum [INN-Latin], Benzocaina [INN-Spanish], 4-amino-benzoic acid ethyl ester, Ethyl aminobenzoate (VAN), Ethylester kyseliny p-aminobenzoove, ETHYL-P-AMINOBENZOATE, Benzocaine Hydrobromide, Benzoic acid, p-amino-, ethyl ester, Caswell No. 430A, Benzocaine [INN:BAN], p-Aminobenzoic acid, ethyl ester, Benzocaine Methanesulfonate, UNII-U3RSY48JW5, Parathesin (TN), ethylaminobenzoate-4, h-4-abz-oet, HSDB 7225, CHEBI:116735, Ethylester kyseliny p-aminobenzoove [Czech], Benzocaine (USP/INN), EINECS 202-303-5, NSC 41531, p-Aminobenzoic ethyl ester, EPA Pesticide Chemical Code 097001, BRN 0638434, U3RSY48JW5, AI3-02081, BLFLLBZGZJTVJG-UHFFFAOYSA-N, Benzocaine HCl, CAS-94-09-7, NCGC00016352-01, DSSTox_CID_1804, WLN: ZR DVO2, DSSTox_RID_76338, DSSTox_GSID_21804, 9011-18-1, AE-562/40377256, Finafta, Benzocaine Acetate, SMR000059025, Acetate, Benzocaine, Formate, Benzocaine, Hydrobromide, Benzocaine, SR-05000001573, Hydrochloride, Benzocaine, Methanesulfonate, Benzocaine, Benzoak, Benzocaine [USP:INN:BAN], Vagisil, Benzocaine USP, Diet Ayds, Orabase-B, Slim Mint Gum, Auralgan (TN), Prestwick_991, 4-carboethoxyaniline, ethyl 4aminobenzoate, ethyl 4-aminobenzate, ethyl 4-aminobezoate, Outgro (Salt/Mix), Anbesol (Salt/Mix), Vagisil (Salt/Mix), ethyl-4-aminobenzoate, p-ethoxycarbonylaniline, 4-ethoxycarbonylaniline, ethyl p-amino-benzoate, ethyl-p-amino-benzoate, Ethyl aminobenzoic acid, Cough-X (Salt/Mix), Spectrum_000074, Ethyl 4-amino-benzoate, ethyl 4-(amino)benzoate, AC1L1DGC, Ethyl p-aminobenzoic acid, Prestwick0_000712, Prestwick1_000712, Prestwick2_000712, Prestwick3_000712, Spectrum2_000117, Spectrum3_000314, Spectrum4_000249, Spectrum5_000860, ethyl 4-aminobenzoic acid, D0Q8ZX, Epitope ID:114084, AC1Q64JE, Anbesol, Cepacol, Lanacane, SAMPL3, G4, Ethyl aminobenzoate (JP15), Ethyl aminobenzoate (JP17), Oprea1_750694, Oprea1_827402, SCHEMBL25100, BSPBio_000923, BSPBio_001908, KBioGR_000658, KBioSS_000474, 4-(Ethoxycarbonyl)phenylamine, 4-14-00-01129 (Beilstein Handbook Reference), KSC264M8P, MLS001331704, MLS002153970, ARONIS27057, DivK1c_000932, Ethyl 4-aminobenzoate, 98%, SPECTRUM1500139, (p-(Ethoxycarbonyl)phenylamine, Ethyl p-aminobenzenecarboxylate, SPBio_000134, SPBio_002844, ACMC-20978l, 112909_ALDRICH, AC1Q341A, BPBio1_001017, CHEMBL278172, 4-aminobenzoic acid-ethyl ester, DTXSID8021804, 4 Aminobenzoic Acid Ethyl Ester, ETHYL PARA AMINO BENZOATE, HMS502O14, KBio1_000932, KBio2_000474, KBio2_003042, KBio2_005610, KBio3_001408, p-amino benzoic acid ethyl ester, 4-amino benzoic acid ethyl ester, Ethylesterkyseliny p-aminobenzoove, NSC4688, MolPort-000-871-526, NINDS_000932, 23239-88-5 (hydrochloride), BDBM197282, HMS1570O05, HMS1920G09, HMS2091M11, HMS2097O05, HMS2233H21, HMS3371D08, HMS3652H13, HMS3714O05, Pharmakon1600-01500139, 112909_SIAL, component of Tympagesic (Salt/Mix), CS-B0934, HY-Y0258, KS-000009QS, KS-000048JY, NSC-4688, NSC41531, Tox21_110391, Tox21_301149, ANW-13651, BBL010501, CCG-38918, MFCD00007892, NSC-41531, NSC755909, s4210, SBB028356, STK043620, ZINC12358719, AKOS000119763, Benzocaine 1.0 mg/ml in Acetonitrile, Ethyl 4-aminobenzoate, 98% 250g, Tox21_110391_1, AC-8127, ACN-034789, AN-8302, AS04671, DB01086, EBD2186554, MCULE-6566052626, NSC-755909, RTR-038495, TRA0057223, IDI1_000932, Benzocaine, purum, >=99.0% (HPLC), Benzocaine, tested according to Ph.Eur., NCGC00016352-02, NCGC00016352-03, NCGC00016352-04, NCGC00016352-07, NCGC00094598-01, NCGC00094598-02, NCGC00255047-01, AJ-61315, AN-20657, BC203342, CJ-13817, Ethyl 4-aminobenzoate, 98.0-101.0%, LS-35847, M024, SC-18075, SBI-0051293.P003, AB1008006, component of Solarcaine aerosol (Salt/Mix), DB-012702, ST2412989, TR-038495, A0271, AB00051923, BB 0258778, FT-0624536, FT-0625762, ST45255315, 4-Aminobenzoic acid ethyl ester (Benzocaine), 1324-EP2280008A2, 1324-EP2315502A1, C07527, D00552, H-4-Abz-Oet; 4-Aminobenzoic acid ethyl ester, M-5932, 66567-EP2284157A1, 66567-EP2308851A1, AB00051923_09, AB00051923_10, component of Anbesol maximum strength (Salt/Mix), Ethyl 4-aminobenzoate, SAJ first grade, >=99.0%, I05-0204, Q-200688, SR-05000001573-1, SR-05000001573-3, BRD-K75466013-001-05-2, BRD-K75466013-001-08-6, Ethyl 4-aminobenzoate, Vetec(TM) reagent grade, 98%, F2190-0448, Benzocaine, European Pharmacopoeia (EP) Reference Standard, Benzocaine, United States Pharmacopeia (USP) Reference Standard, Benzocaine, Pharmaceutical Secondary Standard; Certified Reference Material, 71123-91-6

ID: 248

InChIKey: BLGXFZZNTVWLAY-DKJBZYCGSA-N
SMILES: COC(=O)[C@@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 92766
synonyms found at PubChem are:
corynanthine, 483-10-3, Rauhimbine, UNII-F5Z7C9RK8U, F5Z7C9RK8U, Corynanthin, Rauhimbin, CHEMBL31410, SMR000857089, methyl hydroxy[?]carboxylate, 17|A-Hydroxyyohimban-16|A-carboxylic acid methyl ester, EINECS 207-590-0, NSC 407306, Lopac-R-104, AC1L3OSP, Prestwick0_000578, Prestwick1_000578, Prestwick2_000578, Prestwick3_000578, Lopac-Y-3125, D00GEE, BSPBio_000396, MLS001332619, MLS001332620, SCHEMBL178061, SPBio_002615, BPBio1_000436, GTPL5345, MEGxp0_001869, ACon1_002064, CHEBI:92122, BLGXFZZNTVWLAY-DKJBZYCGSA-N, Bio1_000472, Bio1_000961, Bio1_001450, HMS2231N15, Methyl (16beta,17alpha)-17-hydroxyyohimban-16-carboxylate, ZINC3861548, 6613AF, BDBM50027058, AKOS024282584, CCG-208620, SMP1_000080, NCGC00015878-01, NCGC00015878-02, NCGC00016294-06, ST057156, BRD-K06467078-003-03-7, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16beta,17alpha)-, Yohimban-16beta-carboxylic acid, 17alpha-hydroxy-, methyl ester (8CI), Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16beta,17alpha)- (9CI), (1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'''',3'''':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester, (1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'',3'':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester, 2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'',3'':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester, methyl (1S,15R,18S,19S,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate, methyl (3S,4S,4aS,5aS,14aR)-3-hydroxy-1,2,3,4,5,11,14,14a,4a,5a-decahydrobenzo [3,2-g]indolo[2,3-a]quinolizine-4-carboxylate

ID: 249

InChIKey: BLOIUFYKQCCAGP-UHFFFAOYSA-N
SMILES: C(CCN)CC(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 69398
synonyms found at PubChem are:
5-Aminovaleric acid hydrochloride, 5-Aminopentanoic Acid Hydrochloride, 627-95-2, 4-Carboxybutylammonium chloride, 5-Aminovaleric Acid HCl, 5-Amino-n-valeric Acid Hydrochloride, Pentanoic acid, 5-amino-, hydrochloride, SMR001230701, 4-carboxybutan-1-aminium chloride, EINECS 211-021-1, ACMC-1AZ5K, AC1L2BS2, AC1Q3E7R, MLS002153235, MLS002207086, SCHEMBL644593, SPECTRUM1501126, 660-88-8 (Parent), CHEMBL1256511, CTK8B2051, DTXSID80211773, Homopiperidinic Acid Hydrochloride, BLOIUFYKQCCAGP-UHFFFAOYSA-N, MolPort-003-666-360, HMS1921H07, 5-azanylpentanoic acid hydrochloride, Tox21_500031, ANW-34381, CCG-38971, MFCD00012919, AKOS005216455, AC-6337, LP00031, MCULE-3920398524, VZ30055, 5-Aminovaleric acid hydrochloride, 99%, KS-0000190R, NCGC00093551-01, NCGC00093551-02, NCGC00093551-03, NCGC00093551-04, NCGC00260716-01, AN-10135, KB-73251, SC-92391, MLS-0412455.P017, DB-054288, ST2418613, TL8004268, TR-021599, A0436, EU-0100031, FT-0620030, ST50824421, A833998, SR-01000075594, SR-01000075594-1, I14-19373

ID: 250

InChIKey: BLSQLHNBWJLIBQ-OZXSUGGESA-N
SMILES: CC(C)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441383
synonyms found at PubChem are:
terconazole, 67915-31-5, Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol, Terazol, Fungistat, C26H31Cl2N5O3, Terconazol, Terconazolum, Zazole, CHEBI:82980, Terazol 7 & 3, Terconazol [INN-Spanish], Terconazolum [INN-Latin], Tercospor, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-propan-2-ylpiperazine, Terazol Cream & Suppositories, Terconazole [USAN:INN:BAN], EINECS 267-751-6, NSC 331942, Terazol 3 (TN), Terconazole (USAN/INN), R 42470, R-42470, R 42,470, Panlomyc, NCGC00016912-01, 1-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-(1-methylethyl)piperazine, cis-1-(p-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-isopropylpiperazine, CAS-67915-31-5, (2R,4S)-terconazole, Prestwick3_000495, AC1L9B2M, CHEMBL1306, DSSTox_CID_25498, DSSTox_RID_80917, DSSTox_GSID_45498, SCHEMBL23165, BSPBio_000389, MLS002153844, BIDD:GT0705, BPBio1_000429, DTXSID2045498, MolPort-006-133-612, HMS2096D11, HMS2233C22, HMS3713D11, Pharmakon1600-01503847, HY-B1790, Piperazine, 1-(4-(((2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-(1-methylethyl)-, rel-, Piperazine, 1-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-(1-methylethyl)-, cis-, ZINC3873936, Tox21_110679, BDBM50375318, CT0256, KM1155, NSC760361, AKOS016846147, CCG-213216, CS-6456, DB00251, KS-1463, NSC-760361, KS-00000H43, NCGC00179575-01, AS-14153, SMR001233206, AX8152619, KB-217439, LS-176634, AB00513849, C08080, D00888, AB00513849_07, 915T315, SR-01000841196, J-008500, SR-01000841196-2, BRD-K86204871-001-02-2, BRD-K86204871-001-13-9, UNII-0KJ2VE664U component BLSQLHNBWJLIBQ-OZXSUGGESA-N, 1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(propan-2-yl)piperazine, 1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine, 1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(propan-2-yl)piperazine, 1-[4-[[(2R)-2alpha-(2,4-Dichlorophenyl)-2beta-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4beta-yl]methoxy]phenyl]-4-(1-methylethyl)piperazine

ID: 251

InChIKey: BLXXJMDCKKHMKV-UHFFFAOYSA-N
SMILES: CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4409
synonyms found at PubChem are:
nabumetone, 42924-53-8, Relafen, Arthaxan, 4-(6-methoxynaphthalen-2-yl)butan-2-one, Nabumetona, Relifex, Listran, Relifen, nabumeton, Consolan, Mebutan, Balmox, Relif, 4-(6-Methoxy-2-naphthyl)-2-butanone, Dolsinal, Flambate, Nabumetonum, Unimetone, Prodac, Nabumetonum [INN-Latin], Nabuser, 4-(6-Methoxy-2-naphthalenyl)-2-butanone, UNII-LW0TIW155Z, BRL 14777, BRL-14777, MLS000069541, 2-Butanone, 4-(6-methoxy-2-naphthalenyl)-, BRN 2103472, LW0TIW155Z, SMR000058835, CHEBI:7443, BLXXJMDCKKHMKV-UHFFFAOYSA-N, NCGC00016853-01, 4-(2-Methoxynaphthalen-6-yl)butan-2-one, CAS-42924-53-8, DSSTox_CID_25472, DSSTox_RID_80901, DSSTox_GSID_45472, Nabucox, 4-[6-methoxy-2-naphthyl]-2-butanone, SR-01000759138, nabuton, CCRIS 8108, Nabumetone (oral), Nabumetone [USAN:BAN:INN:JAN], Relafen (TN), Nabumetone [USAN:USP:INN:BAN:JAN], Spectrum_001486, Opera_ID_765, Prestwick0_000909, Prestwick1_000909, Prestwick2_000909, Prestwick3_000909, Spectrum2_001969, Spectrum4_000174, Spectrum5_001286, 6-MNA (oral), Nobex, Nabumetone (oral), Nobex, D05CKR, AC1L1I3P, AC1Q4F4K, cid_4409, SCHEMBL2256, CHEMBL1070, BSPBio_000758, KBioGR_000687, KBioSS_001966, MLS001076325, BIDD:GT0104, DivK1c_000850, SPECTRUM1503650, SPBio_002097, SPBio_002957, Nabumetone, analytical standard, BPBio1_000834, GTPL7245, Nabumetone (JP17/USP/INN), DTXSID4045472, BDBM40128, CTK8B4843, HMS502K12, KBio1_000850, KBio2_001966, KBio2_004534, KBio2_007102, ZINC20221, NNB-001, NNB-004, NNB-005, MolPort-001-793-710, NINDS_000850, HMS1570F20, HMS1922G10, HMS2090D13, HMS2093I05, HMS2097F20, HMS2230H12, HMS3259I16, HMS3652M04, HMS3714F20, Pharmakon1600-01503650, BCP12152, HY-B0559, Tox21_110647, ANW-46490, CCG-39507, MFCD00079518, NSC758623, s4051, AKOS009529199, Tox21_110647_1, 4-(6-methoxy-2-naphthyl)butan-2-one, API0003472, CS-2669, DB00461, KS-1371, NC00579, NSC-758623, IDI1_000850, NCGC00016853-02, NCGC00016853-03, NCGC00016853-06, NCGC00095063-01, NCGC00095063-02, AC-19025, AJ-08410, AK-86115, BC966361, CC-32257, CPD000058835, LS-46825, M727, SAM002564225, SC-77045, ZB000767, SBI-0051869.P002, AX8142896, KB-238680, ST2405403, TC-135235, AB00052392, AM20040460, FT-0629765, D00425, AB00052392-13, AB00052392_14, AB00052392_15, 924N538, C-13097, SR-01000759138-2, SR-01000759138-3, BRD-K65146499-001-04-8, BRD-K65146499-001-14-7, Nabumetone, British Pharmacopoeia (BP) Reference Standard, Nabumetone, European Pharmacopoeia (EP) Reference Standard, Nabumetone, United States Pharmacopeia (USP) Reference Standard

ID: 252

InChIKey: BMGBHVTUOPUVRW-UHFFFAOYSA-N
SMILES: C1CN=C(N1)C2=CC3=C(O2)C=CC(=C3)SC#N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6603748
synonyms found at PubChem are:
BU99006, CHEMBL157351, NCGC00015168-01, Lopac-B-8433, AC1O7G0N, Lopac0_000587, MLS002153225, SCHEMBL2493530, cid_6603748, HMS2230K13, HMS3261F16, Tox21_500587, BDBM50086503, CCG-204676, LP00587, NCGC00015168-02, NCGC00015168-03, NCGC00015168-04, NCGC00093966-01, NCGC00093966-02, NCGC00261272-01, SMR001230696, EU-0100587, B 8433, SR-01000075921, SR-01000075921-1, 2-(5-Thiocyanato-benzofuran-2-yl)-4,5-dihydro-1H-imidazole, [2-(4,5-dihydro-1H-imidazol-2-yl)-1-benzofuran-5-yl] thiocyanate

ID: 253

InChIKey: BNPSSFBOAGDEEL-UHFFFAOYSA-N
SMILES: CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 39859
synonyms found at PubChem are:
Salbutamol sulfate, ALBUTEROL SULFATE, Salbutamol hemisulfate, 51022-70-9, Albuterol hemisulfate, Proventil-HFA, Ventolin, Bronchospray, Aerotec, Aloprol, Amocasin, Broncodil, Dipulmin, Fartolin, Inspiryl, Venetlin, Emican, Loftan, Epaq, Broncho Inhalat, Huma-Salmol, Ventolin HFA, VoSpire ER, AccuNeb, dl-Salbutamol sulfate, Sch 13949W sulfate, Albuterol sulfate(2:1), (+-)-Salbutamol sulfate, Proair HFA, EINECS 256-916-8, NSC 289928, 36519-31-0, Proventil Repetabs, Solution, Syrup, and Tablets, Ventolin (TN), 1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylamino)ethanol sulfate, alpha(sup 1)-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol sulfate (2:1) (salt), Bis((tert-butyl)(beta,3,4-trihydroxyphenethyl)ammonium) sulphate, Proair Respiclick, C13H21NO3.H2O4S, 1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, sulfate (2:1) (salt), 1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, sulfate (2:1) (salt), Albuterol sulfate [USAN], Accuvent, Pediavent, Volare, Albuterol sulfate [USAN:USP], Ventolin Nebules, Salbutamol Diskus, 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;sulfuric acid, Buventol Easyhaler, Proventil Repetabs, Pulvinal salbutamol, Sulbutamol sulphate, Accuneb (TN), Salbutamol Easyhaler, Eae -Ae, Ventolin easy-breathe, Albuterol Sulfate,(S), Albuterol sulfate (USP), Salbutamol hemisulfate salt, AC1L22LX, Salbutamol sulfate (JP17), TBS-7, SCHEMBL33279, bis(salbutamol); sulfuric acid, CHEBI:2550, Salbutamol sulfate, 99% 1g, (+-)-ysulfate(2:1)(salt), CHEMBL1441059, KS-00000RSS, MolPort-003-933-916, HMS3263K18, HMS3266D17, Tox21_501098, BG0312, CA0122, Salbutamol hemisulfate salt, >=98%, (C13H21NO3)2.H2SO4, AKOS015994719, AH-3365, API0004123, CCG-222402, KS-5056, LP01098, TQ-1016, C13H21NO3??1/2H2SO4, salbutamol sulphate (albuterol sulphate), NCGC00094370-01, NCGC00261783-01, H886, LS-29862, SC-18559, AB0013333, LS-162604, TL8003382, EU-0101098, FT-0650809, S0531, D00683, J10322, K-9412, S 5013, 022S709, Salbutamol hemisulfate salt, VETRANAL(TM), analytical standard, Salbutamol sulfate, European Pharmacopoeia (EP) Reference Standard, 4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol hemisulfate, 5-[2-(tert-Butylamino)-1-hydroxyethyl]-2-hydroxybenzyl Alcohol Hemisulfate, Albuterol sulfate, United States Pharmacopeia (USP) Reference Standard, 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; sulfuric acid, Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material, Salbutamol sulfate for system suitability, European Pharmacopoeia (EP) Reference Standard, Salbutamol Sulphate (Albuterol Sulphate) 1.0 mg/ml in Methanol (as free base), 1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-,sulfate (2:1) (salt), AKOS024370983, MCULE-7740078582, ST51007122

ID: 254

InChIKey: BNWJOHGLIBDBOB-UHFFFAOYSA-N
SMILES: COC1=CC(=CC2=C1OCO2)CC=C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4276
synonyms found at PubChem are:
Myristicin, 607-91-0, 6-Allyl-4-methoxy-1,3-benzodioxole, Myristicin (6CI), 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole, Myristicine, 5-Allyl-1-methoxy-2,3-(methylenedioxy)benzene, UNII-04PD6CT78W, 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-, CCRIS 6782, Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-, HSDB 3516, EINECS 210-146-9, 5-Allyl-2,3-(methylendioxy)anisole, BRN 0166218, 04PD6CT78W, 4-Methoxy-6-[2-propenyl]-1,3-benzodioxole, CHEBI:68234, BNWJOHGLIBDBOB-UHFFFAOYSA-N, 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)- (9CI), 4-methoxy-6-prop-2-enyl-2H-benzo[d]1,3-dioxolene, AC1L1HSS, DSSTox_CID_5693, DSSTox_RID_77884, DSSTox_GSID_25693, SCHEMBL68041, 5-19-02-00631 (Beilstein Handbook Reference), MLS001065535, Myristicin, analytical standard, CHEMBL481044, DTXSID1025693, Myristicin from parsley leaf oil, CTK5J3915, MolPort-003-925-569, HMS2270K14, ZINC403089, 6-allyl-4-methoxy-1,3-benzodioxol, Tox21_200172, FCH920323, MFCD00133549, SBB014760, STK693140, AKOS005604763, API0025964, CCG-208543, LS-2163, MCULE-6209105333, 6-allyl-4-methoxybenzo[d][1,3]dioxole, NCGC00091427-01, NCGC00091427-02, NCGC00257726-01, AN-46392, CAS-607-91-0, SC-21462, SMR000112534, ST097616, ZB013050, 3-methoxy,4,5-methylenedioxy-allylbenzene, 4-methoxy-6-prop-2-enyl-1,3-benzodioxole, 1-Allyl-3-methoxy-4,5-methylenedioxybenzene, FT-0672575, V0156, C10480, 5-Allyl-1-methoxy-2,3-(methylenedioxy)-Benzene, 4-methoxy-6-(prop-2-en-1-yl)-1,3-benzodioxole, 607M910, SR-01000838340, 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole, 9CI, SR-01000838340-3, 1-Methoxy-2,3-methylenedioxy-5-(2-propenyl)benzene, 4-methoxy-6-(prop-2-en-1-yl)-2H-1,3-benzodioxole, Myristicin from parsley leaf oil, >=85% (HPLC), oil, NCGC00091427-03!4-methoxy-6-prop-2-enyl-1,3-benzodioxole

ID: 255

InChIKey: BOBLHFUVNSFZPJ-JOYXJVLSSA-N
SMILES: C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)OC(=O)C)C)O)F)C)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71414
synonyms found at PubChem are:
Diflorasone diacetate, 33564-31-7, Psorcon, Florone E, Maxiflor, Apexicon e, Diflorasone di(acetate), UNII-7W2J09SCWX, EINECS 251-575-1, U 34865, BRN 2318163, 7W2J09SCWX, MLS000069559, MLS001076548, CHEBI:31483, 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-diacetate, NCGC00022003-03, SMR000058814, 6alpha-Fluorobetamethasone-17,21 diacetate, Psorcon E, DSSTox_CID_25646, DSSTox_RID_81024, DSSTox_GSID_45646, U-34865, Dermaflor, Diacort, [2-[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyloxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate, Apexicon, Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6alpha,11beta,16beta)-, Murode, Diflorasone diacetate [USAN:JAN], Florone (TN), Psorcon (TN), CAS-33564-31-7, Diflorasone diacetate [USAN:USP:JAN], Acetic acid diflorasone, Opera_ID_1660, Prestwick0_000619, Prestwick1_000619, Prestwick2_000619, Prestwick3_000619, D0G7KJ, AC1L2G4E, AC1Q62MX, SCHEMBL4556, BSPBio_000558, diflorasone 17,21-diacetate, REGID_for_CID_71414, SPBio_002777, BPBio1_000614, GTPL7068, CHEMBL1200545, DTXSID8045646, CTK8F9190, BOBLHFUVNSFZPJ-JOYXJVLSSA-N, HMS1569L20, HMS2096L20, HMS2231D10, HMS3713L20, Diflorasone diacetate (JP17/USP), ZINC4212938, Tox21_110875, AKOS025402039, Tox21_110875_1, AC-3515, AN-6747, BCP9000608, CCG-220619, NCGC00022003-04, NCGC00022003-06, BC226395, Q944, SC-80650, AB2000740, LS-118428, AB00489907, FT-0639113, D01327, 564D317, A821840, SR-01000000122, Q-101374, SR-01000000122-3, U-34,865, BRD-K17674993-001-03-1, Diflorasone diacetate, United States Pharmacopeia (USP) Reference Standard, (6alpha,11beta,16beta)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl diacetate, [2-[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-acetoxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate, [2-[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyloxy-6,9-bis(fluoranyl)-10,13,16-trimethyl-11-oxidanyl-3-oxidanylidene-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxidanylidene-ethyl] ethanoate, 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16 beta-methyl-pregna-1,4-diene-3,20-dione 17,21-diacetate, 6alpha,9-difluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl diacetate, acetic acid [2-[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyloxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester, Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-,(6-alpha,11-beta,16-beta)-

ID: 256

InChIKey: BOCLFQZPFYNVFD-UHFFFAOYSA-N
SMILES: CC1(C2=CC=CC=C2N(C1=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957576
synonyms found at PubChem are:
192927-92-7, LY310762, LY-310,762 hydrochloride, 1-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-3,3-dimethylindolin-2-one hydrochloride, LY310762 HCl, LY310762 hydrochloride, LY-310762, 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride, LY 310762, J-504090, SMR001230659, EU-0100658, LY 310762 hydrochloride, LY-310762 hydrochloride, C24H28ClFN2O2, MLS002153165, MLS006011254, SCHEMBL7833291, CHEMBL1256663, CTK8B6747, KS-00000PDU, DTXSID80474689, EX-A628, LY-310762 HCl, BOCLFQZPFYNVFD-UHFFFAOYSA-N, CHEBI:140935, MolPort-003-947-501, BCP02518, Tox21_500658, ANW-54230, s2669, AKOS015999226, API0007850, CCG-221962, CS-3261, LP00658, RL02431, RTX-011516, NCGC00094020-01, NCGC00261343-01, 4CA-0789, HY-13527, LY-310,762 hydrochloride, white powder, AB0033824, KB-212486, ST2403074, B2250, FT-0700464, X7596, L 2536, Z-3206, SR-01000075569, SR-01000075569-1, 192927-92-7, LY310762, LY 310762, 1-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-3,3-dimethylindol-2-one hydrochloride, 1-[2-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)ethyl]-4-(4-fluorobenzoyl)piperidinium chloride, 1-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-3,3-dimethyl-1,3-dihydro-2H-indol-2-one hydrochloride, 3,3-Dimethyl-1-[2-[4-(4-flurobenzoyl)-1-piperidinyl-1-ethyl-1,3-dihydro-2h-indol-2-one hydrochloride, 3,3-Dimethyl-1-[2-[4-(4-flurobenzoyl)-1-piperidinyl]-1-ethyl]-1,3-dihydro-2h-indol-2-one hydrochloride, 3,3-Dimethyl-1-{2-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-ethyl}-1,3-dihydro-2H-indol-2-one hydrochloride, 3,3-dimethyl-1-{2-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-ethyl}-1,3-dihydro-2H-indol-2-one monohydrochloride

ID: 257

InChIKey: BOCUKUHCLICSIY-UHFFFAOYSA-N
SMILES: C1C2CC(C1C=C2)C3NC4=CC(=C(C=C4S(=O)(=O)N3)S(=O)(=O)N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2910
synonyms found at PubChem are:
cyclothiazide, Anhydron, Aquirel, Renazide, Valmiran, Doburil, Fluidil, 2259-96-3, Ciclotiazida, Ciclotiazide, Cyclothiazidum, Ciclotiazide [DCIT], Ciclotiazida [INN-Spanish], Cyclothiazidum [INN-Latin], MDi 193, Lilly 35,483, UNII-P71U09G5BW, Anhydron (TN), Cyclothiazide [USAN:INN:BAN], HSDB 3310, 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, EINECS 218-859-7, BRN 0722843, CHEMBL61593, 6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, 6-Chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, P71U09G5BW, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-, 1,1-dioxide, Cyclothiazide (JAN/USAN/INN), CHEBI:31448, BOCUKUHCLICSIY-UHFFFAOYSA-N, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo(2.2.1)hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide, 3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-Bicyclo(2.2.1)hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, NCGC00015288-06, DSSTox_CID_2871, C 9847, 6-Chloro-3,4-dihydro-3-(norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, DSSTox_RID_76767, DSSTox_GSID_22871, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-chloro-3-(5-norbornen-2-yl)-, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-chloro-3-(5-norbornen-2-yl)-,1,1-dioxide, 6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide, CAS-2259-96-3, SR-01000075796, 3-(5-bicyclo[2.2.1]hept-2-enyl)-6-chloro-1,1-dioxo-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Cyclothiazide [USAN:USP:INN:BAN], AC1L1EQZ, Spectrum4_000050, Spectrum5_001639, Lilly 35483, Biomol-NT_000224, D03CNS, AC1Q6TQ1, Lopac0_000321, KBioGR_000519, MLS001077326, DivK1c_000904, SCHEMBL121096, BPBio1_001320, GTPL4167, DTXSID3022871, HMS502N06, KBio1_000904, MolPort-003-666-800, NINDS_000904, Cyclothiazide (mixture of isomers), HMS2093A19, HMS2236K04, HMS3261A03, HMS3266L17, HMS3373E04, Pharmakon1600-01503263, Tox21_110124, Tox21_500321, BDBM50192229, NSC758431, AKOS024458615, Tox21_110124_1, CCG-204416, DB00606, LP00321, NSC-758431, IDI1_000904, NCGC00015288-04, NCGC00015288-05, NCGC00015288-07, NCGC00015288-09, NCGC00022985-02, NCGC00024745-02, NCGC00024745-03, NCGC00024745-04, NCGC00261006-01, 6-chloro-3,4-dihydro-3-(norbornen-2-yl)-2H-1,2,4- benzothiadiazine-7-sulfonamide 1,1-dioxide, BC251589, LS-40445, SMR000653479, SBI-0050309.P003, EU-0100321, FT-0665417, C12685, D01256, AB00053281_04, J-014778, SR-01000075796-1, SR-01000075796-3, SR-01000075796-4, BRD-A38675539-001-01-0, BRD-A38675539-001-05-1, 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide, 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide(Clothiazide), 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide #, 3-Bicyclo[2.2.1]hept-5-en-2-yl-7-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[1,2,4]thiadiazine-6-sulfonic acid amide

ID: 258

InChIKey: BOEGTKLJZSQCCD-UEKVPHQBSA-N
SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 47965
synonyms found at PubChem are:
cefadroxil, Cephadroxil, 50370-12-2, Cefadroxil anhydrous, Cefadroxilo, Cefadroxilum, D-Cefadroxil, Duricef, Ultracef, BL-S578, Cefadroxilum [INN-Latin], UNII-Q525PA8JJB, Cefadroxilo [INN-Spanish], Sumacef (TN), CHEBI:3479, BL-S 578, 66592-87-8, S 578, S-578, (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, CDX, Q525PA8JJB, MJF-11567-3, DSSTox_CID_2749, DSSTox_RID_76714, Cefradroxil, DSSTox_GSID_22749, Sumacef, (6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, p-Hydroxycephalexine, EINECS 256-555-6, (6R,7R)-7-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R,7R)-, Cefadroxil [INN], C16H17N3O5S, cefadrox, Cefadrops, CEFADROXIL/CEFADROXIL HEMIHYDRATE, NCGC00016858-01, Curisafe (TN), CAS-50370-12-2, Cefadroxil, Anhydrous, Cefadroxil (JP15), Cefadroxil (JP17), Spectrum_000104, Prestwick0_000434, Prestwick1_000434, Prestwick2_000434, Prestwick3_000434, Spectrum2_000087, Spectrum4_000266, Spectrum5_000663, D0X9ZC, Epitope ID:117131, AC1L2J3O, CHEMBL1644, BSPBio_000448, KBioGR_000732, KBioSS_000544, MLS002207219, DivK1c_000409, SCHEMBL151320, SPBio_000014, SPBio_002387, Cefadroxil, analytical standard, BPBio1_000494, GTPL4831, DTXSID8022749, CTK8F8512, HMS501E11, KBio1_000409, KBio2_000544, KBio2_003112, KBio2_005680, BOEGTKLJZSQCCD-UEKVPHQBSA-N, MolPort-002-507-346, NINDS_000409, HMS1569G10, HMS2096G10, HMS3713G10, Pharmakon1600-01500163, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R-(6-alpha,7-beta(R*)))-, HY-B1190, ZINC3830391, Tox21_110651, BBL033696, BDBM50350467, NSC756664, STK801939, AKOS005622555, Tox21_110651_1, API0006601, CCG-220434, CS-4696, DB01140, MCULE-6475996520, NSC-756664, IDI1_000409, NCGC00179556-01, NCGC00179556-03, AS-11655, SC-74593, SMR001306770, SBI-0051305.P003, AB00513838, FT-0603067, ST51014960, C06878, D00257, 592C878, I04-8441, Cefadroxil monohydrate, Antibiotic for Culture Media Use Only, (7R)-7-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetylamino](7R,7aR)-3-methyl-6-oxo-2H,7H-a zetidino[2,1-b]1,3-thiazine-4-carboxylic acid, 7beta-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid, 7beta-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-3,4-didehydrocepham-4-carboxylic acid, AC1O6OSB, (6R,7R)-7-[[(2R)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

ID: 259

InChIKey: BOJKFRKNLSCGHY-HXGSDTCMSA-N
SMILES: C[C@@H]1C[C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)OC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 454217
synonyms found at PubChem are:
Prostratin, 12-Deoxyphorbol-13-acetate, 60857-08-1, CHEBI:69818, 12-Deoxyphorbol 13-acetate, (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one, CCRIS 6292, 13-O-Acetylphorbol, NSC 623310, Prostatin >99%, Stillingia Factor S7, AC1L9RHH, SCHEMBL344837, CHEMBL170518, Prostratin, >=98% (HPLC), BOJKFRKNLSCGHY-HXGSDTCMSA-N, MolPort-006-395-783, HMS3648K03, ZINC3915682, 2017AH, BDBM50368315, AKOS027250797, CCG-208192, SMP2_000144, 12-deoxyphorbol-13-acetate (prostratin), FT-0674123, C20197, SR-01000946228, SR-01000946228-1, BRD-K91145395-001-01-9, 4a,7b-Dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate

ID: 260

InChIKey: BOJKULTULYSRAS-OTESTREVSA-N
SMILES: C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2C/C=C/3\[C@@H](COC3=O)O)(C)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5318517
synonyms found at PubChem are:
Andrographolide, 5508-58-7, Andrographis, UNII-410105JHGR, CHEBI:65408, 410105JHGR, (S,E)-4-Hydroxy-3-(2-((1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)ethylidene)dihydrofuran-2(3H)-one, 3-(2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthyl)ethylidene)dihydro-4-hydroxyfuran-2(3H)-one, EINECS 226-852-5, NSC 383468, 3alpha,14,15,18-tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic acid gamma-Lactone, (1R-(1-alpha(E(S)),4abeta,5alpha,6alpha,8aalpha))-3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-2(3H)-furanone, (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one, (3E,4S)-4-hydroxy-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one, NSC383468, NCGC00095597-01, Andrographolide, 98%, AC1NSWY5, D04VIS, DSSTox_CID_25980, DSSTox_RID_81270, DSSTox_GSID_45980, BIDD:ER0530, CHEMBL186141, GTPL9675, MEGxp0_000978, DTXSID3045980, SCHEMBL12056309, ACon1_002113, BOJKULTULYSRAS-OTESTREVSA-N, MolPort-001-741-138, 2(3H)-Furanone, 3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-, (1R-(1-alpha(E(S*)),4a-beta,5-alpha,6-alpha,8a-alpha))-, ACT03252, Andrographolide, analytical standard, HY-N0191, ZINC3881797, Tox21_111508, BDBM50084419, CA0137, AKOS015920075, CCG-208428, CS-3334, DB05767, MCULE-5521128905, NCGC00179817-01, 2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E,4S)-, AJ-46652, AK-47364, AS-13637, BR-47364, SC-46922, CAS-5508-58-7, AX8009106, KB-280038, ST2414690, C20214, J10022, S-1899, 508A587, Q-100624, BRD-K89282837-001-01-0, Andrographolide, United States Pharmacopeia (USP) Reference Standard, (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-decalin-1-yl]ethylidene]-4-hydroxy-tetrahydrofuran-2-one, (3E,4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one, (5beta,9R,10alpha,14S)-3alpha,14,15,18-Tetrahydroxylabdane-8(20),12-diene-16-oic acid gamma-lactone, (S,E)-4-Hydroxy-3-(2-((1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)ethylidene)dihydrofuran-2, 2(3H)-Furanone,3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-,(3E,4S)-

ID: 261

InChIKey: BONORRGKLJBGRV-UHFFFAOYSA-N
SMILES: CN(C)CCN(CC1=CC=CS1)C2=CC=CC=N2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 8667
synonyms found at PubChem are:
METHAPYRILENE HYDROCHLORIDE, Methapyrilene HCl, Methoxylene, 135-23-9, Capathyn, Histadyl, Methacon, Somnicaps, Barhist, Coryzol, Teralin, Dozar, Tem-Histine, Blue Line, Thenylene hydrochloride, Thenylpyramine hydrochloride, Semikon hydrochloride, W-53 hydrochloride, Compound 01013, Methapyrilene.HCl, CCRIS 379, UNII-00S42N58OM, EINECS 205-184-8, methypyrilene hydrochloride, MLS000069777, CHEBI:38213, 00S42N58OM, 2-((2-(Dimethylamino)ethyl)-2-thenyl-amino)pyridine hydrochloride, 2-((2-(Dimethylamino)ethyl)-2-thenylamino)pyridine monohydrochloride, Methapyriline, NCGC00094179-02, SMR000058482, DSSTox_CID_818, N,N-Dimethyl-N'-(2-pyridyl)-N'-(2-thenyl)ethylenediamine hydrochloride, Ethylenediamine, N,N-dimethyl-N'-(2-pyridyl)-N'-(2-thenyl)-, hydrochloride, N,N-Dimethyl-N'-(2-thenyl)-N'-(2-pyridyl-ethylene-diamine hydrochloride), 1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-, monohydrochloride, DSSTox_RID_75806, DSSTox_GSID_20818, 2-[[2-(dimethylamino)ethyl]-2-thenylamino]pyridine monohydrochloride, Pyridine, 2-((2-(dimethylamino)ethyl)-2-thenylamino)-, monohydrochloride, 1,2-Ethanediamine, N1,N1-dimethyl-N2-2-pyridinyl-N2-(2-thienylmethyl)-, hydrochloride (1:1), N,N-dimethyl-N'-pyridin-2-yl-N'-(2-thienylmethyl)ethane-1,2-diamine hydrochloride, N,N-dimethyl-N'-pyridin-2-yl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine;hydrochloride, SR-01000076014, CAS-135-23-9, cohistine, histidyl, C14H19N3S.ClH, [2-(dimethylamino)ethyl]-2-pyridyl(2-thienylmethyl)amine, chloride, Methapyrilene hydrochloride [USP], Thenylpyramine HCl, Prestwick_572, histadyl hydrochloride, th enylene hydrochloride, Opera_ID_393, AC1L1RGP, AC1Q3CNE, thenyl d.p.e. hydrochloride, C14H19N3S.HCl, MLS001148453, MLS002222225, BIDD:GT0034, SCHEMBL498484, SPECTRUM1503229, Win 2848 hydrochloride salt, CHEMBL1255739, DTXSID0020818, CTK3I8977, HMS1569E05, HMS1922K13, Pharmakon1600-01503229, Tox21_111256, Tox21_201134, Tox21_500851, 2540AH, CCG-39524, LS-788, NSC758410, SBB058167, Methapyrilene HCl, analytical standard, Tox21_111256_1, API0003327, DB04819, LP00851, MCULE-1095862734, NSC-758410, NCGC00015704-09, NCGC00094179-01, NCGC00094179-03, NCGC00094179-04, NCGC00094179-05, NCGC00258686-01, NCGC00261536-01, EU-0100851, FT-0671128, ST51015067, VU0244473-4, M 9125, J-006670, SR-01000076014-1, SR-01000076014-6, 2-((2-(dimethylamino)ethyl)-2-thenylamino)pyridine hydrochloride, METHAPYRILENE HYDROCHLORIDE (SEE ALSO METHAPYRILENE 91-80-5), N,N-dimethyl-N' -(2-thenyl)-N'-(2-pyridyl)-ethylenediamine hydrochloride, N,N-dimethyl-N'-(2-thenyl)-N'-(2-pyridyl)-ethylenediamine hydrochloride, Ethanediamine, N,N-dimeth yl-N'-2-pyridinyl-N'-(2-thienylmethyl)-, monohydrochloride, Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-, monohydrochloride, N,N-Dimethyl-N'-(2-pyridinyl)-N'-(2-thienylmethyl)-1,2-ethanediamine hydrochloride, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine monohydrochloride, N,N-dimethyl-N'-pyridin-2-yl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine hydrochloride, N,N-dimethyl-N'-pyridin-2-yl-N'-[(thiophen-2-yl)methyl]ethane-1,2-diamine hydrochloride, N-(2-pyridyl)-N-(2-thienylmethyl)-N',N'-dimethyl-ethy lenediamine hydrochloride, N-(2-pyridyl)-N-(2-thienylmethyl)-N',N'-dimethyl-ethylenediamine hydrochloride, 8048-01-9

ID: 262

InChIKey: BOVGTQGAOIONJV-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3475
synonyms found at PubChem are:
gliclazide, 21187-98-4, Glimicron, Diamicron, Nordialex, Diaikron, Gliclazida, Gliklazid, Glyclazide, Gliclazidum [INN-Latin], Gliclazida [INN-Spanish], Gliclazidum, Glimicron (TN), 1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea, 1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea, C15H21N3O3S, CHEBI:31654, 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea, S 1702, N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide, S 852, S-852, Gliclazide [BAN:INN:DCF:JAN], S-1702, N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea, 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea, SE 1702, SE-1702, DSSTox_CID_3095, DSSTox_RID_76872, DSSTox_GSID_23095, 1-[3-Azabicyclo[3.3.0]oct-3-yl]-3-p-toluenesulfonylurea, Diabrezide, 1-(3-azabicyclo[3.3.0]oct-3-yl)-3-(p-tolylsulfonyl)urea, Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-, N-((hexahydrocyclopenta[c]pyrrol-2(1H)-yl)carbamoyl)-4-methylbenzenesulfonamide, N-[(hexahydrocyclopenta[c]pyrrol-2(1H)-ylamino)carbonyl]-4-methylbenzenesulfonamide, SMR000542971, SR-01000816184, diabezidum, diabyl, diaprel, dizalid, gliclazid, glinormax, glyzide, EINECS 244-260-5, Mylan-Gliclazide, Diamicron MR, PMS-Gliclazide, Urea, 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-, Urea, 1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-, Benzenesulfonamide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-, Gliclazide,(S), BRN 1657836, Diamicron (TN), NCGC00016751-01, Prestwick_869, Dianorm (TN), CAS-21187-98-4, Glubitor-OD (TN), Gliclazide (Diamicron), Spectrum_001478, SpecPlus_000870, Gliclazide (JAN/INN), Prestwick0_000558, Prestwick1_000558, Prestwick2_000558, Prestwick3_000558, Spectrum3_001862, Spectrum4_000598, Spectrum5_000753, D0M2MR, Gliclazide (JP17/INN), AC1L1G0Q, SCHEMBL16387, BSPBio_000635, BSPBio_003304, KBioGR_001096, KBioSS_001958, MLS001215197, MLS001304077, MLS001304118, DivK1c_006966, Gliclazide, powder, >=98%, SPECTRUM1504145, SPECTRUM1505013, SPBio_002556, BPBio1_000699, CHEMBL427216, DTXSID9023095, CTK7G8576, KBio1_001910, KBio2_001958, KBio2_004526, KBio2_007094, KBio3_002806, BOVGTQGAOIONJV-UHFFFAOYSA-N, MolPort-002-507-779, HMS1569P17, HMS1922D15, HMS2090K16, HMS2096P17, HMS2855P09, HMS3656C22, HMS3713P17, Pharmakon1600-01504145, BCP21240, HY-B0753, Tox21_110590, ANW-43362, BBL012275, BDBM50103512, BG0208, MFCD00409893, NSC758673, s2601, SBB066074, STK803142, AKOS003237903, AKOS016340698, Tox21_110590_1, AB05958, API0002840, CCG-213918, CS-2963, DB01120, KS-1067, MCULE-7993816491, NSC-758673, RP17658, NCGC00095107-01, NCGC00095107-02, NCGC00095107-03, NCGC00095107-04, NCGC00095107-05, NCGC00095107-06, NCGC00095107-09, NCGC00095107-10, AC-12045, AN-17308, ST076805, SBI-0052662.P002, AB0012093, AB1004595, LS-160299, AB00053165, FT-0626712, G0381, D01599, K-6100, AB00053165-09, AB00053165_10, AB00053165_11, 187G984, A815188, I06-0117, J-013905, J-522753, SR-01000816184-2, SR-01000816184-3, SR-01000816184-4, BRD-A61154809-001-04-3, Gliclazide, British Pharmacopoeia (BP) Reference Standard, Gliclazide, European Pharmacopoeia (EP) Reference Standard, 1-[(4-methylbenzene)sulfonyl]-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea, 3-{hexahydro-1H-cyclopenta[c]pyrrol-2-yl}-1-(4-methylbenzenesulfonyl)urea, [(3-azabicyclo[3.3.0]oct-3-yl)amino]-N-[(4-methylphenyl)sulfonyl]carboxamide, 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonyl-urea, 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(p-tolylsulfonyl)urea, 2-(((((4-ME-PHENYL)SULFONYL)AMINO)CARBONYL)AMINO)OCTAHYDROCYCLOPENTA(C)PYRROLE, Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-, N-(3-azabicyclo[3.3.0]oct-3-yl){[(4-methylphenyl)sulfonyl]amino}carboxamide, N-[[(HEXAHYDROCYLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYLBENZENESULFONAMIDE, BENZENESULFONAMIDE, N-[[(HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYL

ID: 263

InChIKey: BOWVQLFMWHZBEF-KTKRTIGZSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)NCCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5283454
synonyms found at PubChem are:
n-oleoylethanolamine, oleoylethanolamide, N-(2-Hydroxyethyl)oleamide, 111-58-0, Oleylethanolamide, N-oleoyl ethanolamine, Oleamide MEA, Oleoyl monoethanolamide, Oleoyl Ethanolamide, N-(2-Hydroxyethyl)-9-octadecenamide, N-(Hydroxyethyl)oleamide, UNII-1HI5J9N8E6, N-oleoylethanolamide, N-oleoyl ethanolamide, (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Oleic acid ethanolamide, N-(9Z-octadecenoyl)-ethanolamine, EINECS 203-884-8, N-(cis-9-octadecenoyl) ethanolamine, N-(hydroxyethyl) oleamide, OEA, MLS002153155, 1HI5J9N8E6, CHEMBL280065, (9Z)-N-(2-hydroxyethyl)octadec-9-enamide, CHEBI:71466, Monoethanolamine oleic acid amide, 9-Octadecenamide, N-(2-hydroxyethyl)-, (Z)-, BOWVQLFMWHZBEF-KTKRTIGZSA-N, N-2-Hydroxyethyl-9(Z)-octadecenamide, 9-Octadecenamide, N-(2-hydroxyethyl)-, W-109412, 9-Octadecenamide, N-(2-hydroxyethyl)-, (9Z)-, N-(cis-9-Octadecenoyl)ethanolamine, OLEIC MONOETHANOLAMIDE, N-OEA, SR-01000076041, N-(2-hydroxyethyl)octadec-9-enamide, oleoyl 1-ethanolamide, Tocris-1484, N-Oleoyl-2-aminoethanol, AC1NR2BS, Oleoylethanolamide (OEA), Spectrum5_002037, Lopac-O-0383, 9Z-octadecenoylethanolamide, Oleic acid monoethanolamide, D07MBC, Lopac0_000942, SCHEMBL177713, GTPL2661, DTXSID1044516, BDBM29080, MolPort-003-959-060, N-(9Z-octadecenoyl) ethanolamine, HMS2233E21, HMS3262N06, HMS3649J05, ZINC8034993, Tox21_500942, BS0139, LMFA08040015, MFCD00045972, N-Oleoylethanolamine, ~98% (TLC), AKOS015839895, N-(2-Hydroxyethyl)-9Z-octadecenamide, CCG-205023, LP00942, NCGC00015761-01, NCGC00015761-02, NCGC00015761-03, NCGC00015761-04, NCGC00015761-05, NCGC00015761-06, NCGC00015761-07, NCGC00025182-01, NCGC00025182-02, NCGC00025182-04, NCGC00025182-05, NCGC00025182-06, NCGC00261627-01, AK116336, AS-15152, LS-97729, O253, SMR001230650, (Z)-N-(2-hydroxyethyl)-9-octadecenamide, (9Z)-N-(2-Hydroxyethyl)-9-octadecenamide, AB1005568, AX8017536, HY-107542, KB-258121, CS-0028847, EU-0100942, ST24048305, C20792, J10351, O 0383, 111O580, A802386, SR-01000076041-1, SR-01000076041-3, SR-01000076041-8, UNII-3VVG2UI23S component BOWVQLFMWHZBEF-KTKRTIGZSA-N, UNII-C80684146D component BOWVQLFMWHZBEF-KTKRTIGZSA-N, N-oleoyl ethanolamine, Oleoyl monoethanolamide, Oleoylethanolamide, N-(Hydroxyethyl)oleamide; N-(cis-9-Octadecenoyl)ethanolamine; OEA, oleoylethanolamide

ID: 264

InChIKey: BPGVKIFGOXGHPB-UHFFFAOYSA-N
SMILES: CC(=CCC1=C2C(=C(C3=C1OC(=C(C3=O)O)C4=CC=CC=C4)O)C=CC(O2)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4020240
synonyms found at PubChem are:
Sericetin, KBio1_001233, Spectrum_000230, SpecPlus_000193, AC1N2DSC, Spectrum2_001897, Spectrum3_001265, Spectrum4_001525, Spectrum5_000030, BSPBio_002830, KBioGR_001930, KBioSS_000710, SPECTRUM201581, DivK1c_006289, SPBio_001834, CHEMBL1495541, CHEBI:92096, KBio2_000710, KBio2_003278, KBio2_005846, KBio3_002330, CCG-38470, LMPK12111649, SDCCGMLS-0066871.P001, NCGC00095833-01, NCGC00095833-02, NCGC00178448-01, BRD-K05433219-001-01-8, 5,7-dihydroxy-2,2-dimethyl-10-(3-methylbut-2-enyl)-8-phenylpyrano[3,2-g]chromen-6-one, 42438-75-5

ID: 265

InChIKey: BPICBUSOMSTKRF-UHFFFAOYSA-N
SMILES: CC1=C(C(=CC=C1)C)NC2=NCCCS2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5707
synonyms found at PubChem are:
xylazine, 7361-61-7, Rompun, N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, Xylazin, Narcoxyl, Xylzin, Xylazinum [INN-Latin], Bayer 1470, Xilazina [INN-Spanish], UNII-2KFG9TP5V8, 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, BAY 1470, Anased, WH 7286, Xylazine (free base), 2-(2,6-Dimethylanilino)-5,6-dihydro-4H-1,3-thiazine, EINECS 230-902-1, 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine, 2KFG9TP5V8, 2,6-Xylidine, N-(5,6-dihydro-4H-1,3-thiazinyl)-, 4H-1,3-Thiazine, 5,6-dihydro-2-(2,6-xylidino)-, MLS000054617, CHEMBL297362, 2-(2,6-Dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazine, BAY-VA-1470, BPICBUSOMSTKRF-UHFFFAOYSA-N, NCGC00016098-07, SMR000061135, CAS-7361-61-7, DSSTox_CID_20643, DSSTox_RID_79519, DSSTox_GSID_40643, Primazine, Rometar, Sedomin, Xilazina, Xylaxine, Xylazinum, 4H-1,3-Thiazine-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine, 2-[2,6-Dimethylphenylamino]-4H-5,6-dihydroxthiazine, (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine;N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, SR-01000075296, Xylazine [USP:INN:BAN], Xylazine [USAN:INN:BAN], Xylapan, Xylasol, Xylazine(Rompun), xylazine free base, Chanazine (TN), Prestwick_962, Rompun (Salt/Mix), 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride, Xylapan (Salt/Mix), Xylasol (Salt/Mix), Spectrum_001267, Xylazine (USP/INN), Xylazine, >=99%, AC1L1KYH, Opera_ID_1260, Prestwick0_000598, Prestwick1_000598, Prestwick2_000598, Prestwick3_000598, Spectrum2_001448, Spectrum3_001472, Spectrum4_000239, Spectrum5_001250, Lopac-X-1251, D0Y2JI, Lopac0_001249, SCHEMBL15487, BSPBio_000476, BSPBio_003023, GTPL523, KBioGR_000937, KBioSS_001747, KSC638G6L, MLS000881122, DivK1c_000449, SPECTRUM1501200, SPBio_001315, SPBio_002695, BPBio1_000524, ZINC2248, DTXSID3040643, BCBcMAP01_000167, CHEBI:92386, CTK5D8365, HMS501G11, KBio1_000449, KBio2_001747, KBio2_004315, KBio2_006883, KBio3_002523, MolPort-000-869-370, NINDS_000449, HMS1569H18, HMS1921P17, HMS2089E20, HMS2092L07, HMS2096H18, HMS2232F24, HMS3369L20, HMS3713H18, Pharmakon1600-01501200, BCP03045, HY-B0443, KS-00000H9L, Tox21_110303, BDBM50027069, CCG-39193, KM1558, MFCD00057908, NSC758142, SBB038475, 23076-35-9 (mono-hydrochloride), AKOS000115960, Tox21_110303_1, CS-2549, NSC-758142, TRA0042707, IDI1_000449, SMP1_000319, NCGC00016098-01, NCGC00016098-02, NCGC00016098-03, NCGC00016098-04, NCGC00016098-05, NCGC00016098-06, NCGC00016098-08, NCGC00016098-09, NCGC00016098-11, NCGC00038586-02, NCGC00038586-03, NCGC00038586-04, NCGC00038586-05, Xylazine (base and/or unspecified salts), AC-22589, AJ-08151, AK117805, AS-54468, BC252840, SC-47279, BCP0726000235, SBI-0051216.P003, AB2000618, LS-150494, FT-0654963, X5891, D08683, AB00052246-13, AB00052246-15, AB00052246-16, AB00052246_17, AB00052246_18, 361X617, C-46044, L001033, I06-1056, SR-01000075296-4, SR-01000075296-6, BRD-K21565985-001-05-0, BRD-K21565985-001-15-9, (2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-amine, (2,6-dimethylphenyl)-4,5-dihydro-6H-1,3-thiazin-2-ylamine, 4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, 4H-1,3-Thiazine-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro- (9CI), 29335-81-7

ID: 266

InChIKey: BPMVRAQIQQEBLN-OBPBNMOMSA-N
SMILES: COC(=O)N=N/C=C/1\C=[N+](C2=CC=CC=C2N1O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5353472
synonyms found at PubChem are:
CARBADOX, 6804-07-5, UNII-M2X04R2E2Y, Getroxel, Mecadox, MLS001333201, M2X04R2E2Y, GS-6244, SMR000857182, DSSTox_CID_23913, DSSTox_RID_80088, DSSTox_GSID_43913, Fortigro, Karbadox [Czech], methyl N-[(E)-(1-hydroxy-4-oxidoquinoxalin-4-ium-2-ylidene)methyl]iminocarbamate, N-[(E)-(1-hydroxy-4-oxido-quinoxalin-4-ium-2-ylidene)methyl]iminocarbamic acid methyl ester, CAS-6804-07-5, Carbadoxum [INN-Latin], Carbadox [USAN:INN:BAN], SR-05000001715, CCRIS 3002, HSDB 7028, Carbadoxum, Karbadox, EINECS 229-879-0, 3-(2-Quinoxalinylmethylene)carbazic acid methyl ester N,N'-dioxide, N-[(1E)-2-(1,4-dihydroxyquinoxalin-2-yl)-1-azavinyl]methoxycarboxamide, GS 6244, Spectrum2_000833, Spectrum3_001954, W-104691, 2-Formylquinoxaline 1,4-dioxide carbomethoxyhydrazone, AC1NS48Y, Methyl 3-(2-quinoxalinylmethylene)carbazate-N1,N4-dioxide, BSPBio_003554, 3-(2-Chinoxalinylmethylen-1,4-dioxid)methylkarbazat [Czech], MLS001333202, CHEMBL13779, SCHEMBL193112, SPECTRUM1505294, SPBio_000785, DTXSID6043913, Methyl 3-(2-quinoxalinylmethylene)carbazate N(sup 1),N(sup 4)-dioxide, SCHEMBL10762495, BDBM58923, cid_5353472, KBio3_002870, Carbazic acid, 3-(2-quinoxalinylmethylene)-, methyl ester, N(sup 1),N(sup 4)-dioxide, Hydrazinecarboxylic acid (2-quinoxalinylmethylene)-, methyl ester N(sup 1),N(sup 4)-dioxide, MolPort-003-666-628, HMS1922B06, HMS2090M03, HMS2093O20, HMS2232J20, HMS3713J12, Pharmakon1600-01505294, HY-B1340, Hydrazinecarboxylic acid, (2-quinoxalinylmethylene)-, methyl ester N(sup 1),N(sup 4)-dioxide, Tox21_111456, CCG-39539, DL-343, MFCD00057293, NSC758942, SBB058137, AKOS015895709, Tox21_111456_1, CS-8210, NSC-758942, NCGC00095156-03, NCGC00095156-06, AC-11698, BC203170, TR-022784, ST51014956, AB01275499-01, AB01275499_02, AB01275499_03, 3-(2-Chinoxalinylmethylen-1,4-dioxid)methylkarbazat, SR-05000001715-1, SR-05000001715-3, 3-[2-Quinoxalinylmethylene]carbazic acid methyl ester-N,N'-dioxide, Methyl (2E)-2-[(1,4-dioxido-2-quinoxalinyl)methylene]hydrazinecarboxylate, 2-({[(methoxycarbonyl)amino]imino}methyl)quinoxaline-1,4-diium-1,4-bis(olate), 3-({[(methoxycarbonyl)amino]imino}methyl)quinoxaline-1,4-diium-1,4-bis(olate), Hydrazinecarboxylic acid, (2-quinoxalinylmethylene)-, methyl ester, N,N'-dioxide (9CI), methyl N-[(E)-(1,4-dioxidoquinoxaline-1,4-diium-2-yl)methylideneamino]carbamate, methyl N-[(E)-(4-oxidanidyl-1-oxidanyl-quinoxalin-4-ium-2-ylidene)methyl]iminocarbamate, N-[(E)-(1-hydroxy-4-oxido-2-quinoxalin-4-iumylidene)methyl]iminocarbamic acid methyl ester, 39310-25-3

ID: 267

InChIKey: BPYKTIZUTYGOLE-IFADSCNNSA-N
SMILES: CC1=C(NC(=C1CCC(=O)O)CC2=C(C(=C(N2)/C=C\3/C(=C(C(=O)N3)C)C=C)C)CCC(=O)O)/C=C\4/C(=C(C(=O)N4)C=C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5280352
synonyms found at PubChem are:
bilirubin, 635-65-4, Hematoidin, Hemetoidin, Principal bile pigment, UNII-RFM9X3LJ49, Bilirubin IXalpha, Bilirubin IX-alpha, EINECS 211-239-7, NSC 26685, BRN 0074376, RFM9X3LJ49, AI3-23078, 21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-, CHEBI:16990, BPYKTIZUTYGOLE-IFADSCNNSA-N, PHEOPHYTIN, Biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-, 3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Calcium bilirubinate, 635-65-4 (Parent), Basinite, 93891-87-3, BILIRUBIN (ALPHA), Disodium bilirubinate IXalpha, CCRIS 9347, bilirubin-IXalpha, bilirubin(Z,Z), Bilirubin,(S), EINECS 299-468-9, Bilirubin, 98%, Bilirubin IX.alpha., AC1NQWXK, Spectrum5_000410, bmse000627, D0O8ZV, SCHEMBL19065, BSPBio_002531, 5-26-15-00523 (Beilstein Handbook Reference), SPECTRUM1500857, CHEMBL501680, GTPL4577, SCHEMBL5086205, MolPort-000-771-191, S00334a, 18422-02-1 (calcium salt), 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid, 3-{2-({3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl}methyl)-4-methyl-5-[(Z)-(4-methyl-5-ox, ALBB-030171, BCP13520, BDBM50442897, CCG-38548, HSCI1_000394, MFCD00005499, ZINC18007499, AKOS015895627, Bilirubin, purum, >=95.0% (UV), SDCCGMLS-0066651.P001, VA10406, 93891-87-3 (di-hydrochloride salt), NCGC00095645-01, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid, 18422-02-1, AC-20194, Disodium 1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-2,17-divinyl-21H-biline-8,12-dipropionate, LS-43989, SC-46396, TL8004437, 3079-EP2305695A2, 3079-EP2305696A2, 3079-EP2305697A2, 3079-EP2305698A2, C00486, methyl-5-((Z)-(4-methyl-5-oxo-3-vinyl-1H-, 3-(2-((3-(2-carboxyethyl)-4-methyl-5-((Z), 635B654, Bilirubin, >=98% (EmM/453 = 60), powder, SR-05000002757, I06-0986, SR-05000002757-1, pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid, 11053-42-2, 114-24-9, 188341-33-5, 19245-52-4, 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid, 21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-, calcium salt, 21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-, disodium salt, 3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid, 3-(2-((3-(2-carboxyethyl)-4-methyl-5-((Z)-(3-methyl-5-oxo-4-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((Z)-(4-methyl-5-oxo-3-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrr, 3-(2-((3-(2-carboxyethyl)-4-methyl-5-((Z)-(3-methyl-5-oxo-4-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((Z)-(4-methyl-5-oxo-3-vinyl-1H-pyrrol-2(5H)-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid, 3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene #, 3-(2-{[3-(2-carboxyethyl)-5-{[(2Z)-3-ethenyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-2-yl]methyl}-5-{[(2Z)-4-ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid, 3-(2-{[3-(2-carboxyethyl)-5-{[(2Z)-4-ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-2-yl]methyl}-5-{[(2Z)-3-ethenyl-4-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]methyl}-4-methyl-1H-pyrrol-3-yl)propanoic acid, 39372-61-7, 493-86-7, 55527-40-7, 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione, 856927-39-4, 917-01-1

ID: 268

InChIKey: BPYQCLJKNXNSFK-UHFFFAOYSA-M
SMILES: C1N2C=C(C=C(C2=NC3=C(C=C(C=[N+]31)Br)Br)Br)Br.[I-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 404651
synonyms found at PubChem are:
NSC721079, AC1L8NPW, CTK5I6225, NSC-721079, 1,3,9,11-tetrabromo-6h-dipyrido[1,2-a:2',1'-d][1,3,5]triazin-5-ium iodide

ID: 269

InChIKey: BQDRKSSNLHIYIM-DFIIIIPRSA-N
SMILES: C[C@@]12CCC3[C@]4(CCC(=O)C(C4C[C@H]([C@]3(C1=CC(=O)O[C@H]2C5=COC=C5)C)O)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708643
synonyms found at PubChem are:
KBio3_000694, Spectrum_000557, SpecPlus_000297, Spectrum2_000338, Spectrum3_000087, Spectrum4_001373, Spectrum5_000046, AC1O8FH1, BSPBio_001614, KBioGR_001666, KBioSS_001037, SPECTRUM100458, DivK1c_006393, SPBio_000375, SCHEMBL12998468, KBio1_001337, KBio2_001037, KBio2_003605, KBio2_006173, CCG-38613, DIHYDRO-7-DESACETYLDEOXYGEDUNIN, SDCCGMLS-0066314.P001, NCGC00179148-01, BRD-A47144777-001-01-7, (1R,4bR,5R,10aR,12aR)-1-(furan-3-yl)-5-hydroxy-4b,7,7,10a,12a-pentamethyl-5,6,6a,9,10,10b,11,12-octahydro-1H-naphtho[2,1-f]isochromene-3,8-dione

ID: 270

InChIKey: BQJODPIMMWWMFC-UHFFFAOYSA-N
SMILES: CCN(CC)C(=O)C1=CC(=C(C=C1)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9363
synonyms found at PubChem are:
ETHAMIVAN, Etamivan, Vanillic acid diethylamide, Etamivanum, Emivan, 304-84-7, Analepticon, Cardiovanil, Corivanil, Diethamivan, Simaron, Vandid, Diethylvanillamide, Ventilone, Romecor, Sevanil, N,N-Diethylvanillamide, Cardiovamil, Sevinal, Diethylamide de vanillique, N,N-Diethyl-4-hydroxy-3-methoxybenzamide, Vanillic acid N,N-diethylamide, Vanillinsaeure-diaethylamid, Benzamide, N,N-diethyl-4-hydroxy-3-methoxy-, Vanillamide, N,N-diethyl-, 3-Methoxy-4-hydroxybenzoic acid diethylamide, Etamivanum [INN-Latin], UNII-M44O63YPV9, Vanillinsaeure-diaethylamid [German], EINECS 206-157-3, NSC 406087, BRN 2694478, AI3-20163, MLS000028445, N,N-diethyl-4-hydroxy-3-methoxy-benzamide, M44O63YPV9, BQJODPIMMWWMFC-UHFFFAOYSA-N, NSC406087, NSC-406087, NCGC00015397-02, NCGC00015397-06, CAS-304-84-7, SMR000058359, DSSTox_CID_3007, DSSTox_RID_76829, DSSTox_GSID_23007, N,N-diethyl(4-hydroxy-3-methoxyphenyl)carboxamide, SR-01000003047, Ethamivan [USAN:BAN], Ethamivan [USAN:USP], 2xdl, Etamivan [INN], Prestwick_909, vanillic diethylamide, Vandid (TN), Vanillamide,N-diethyl-, Opera_ID_522, Ethamivan (USAN/INN), AC1L1SVY, AC1Q2YSL, Prestwick0_000500, Prestwick1_000500, Prestwick2_000500, Prestwick3_000500, Lopac-E-0137, Lopac0_000459, BSPBio_000399, ZINC266, 4-10-00-01481 (Beilstein Handbook Reference), MLS001146918, SCHEMBL119823, SPBio_002320, BPBio1_000439, CHEMBL1229908, DTXSID3023007, vanillic acid N,N-diethyl amide, CHEBI:92675, CTK8G3727, KS-00001FAQ, MolPort-001-791-638, HMS1569D21, HMS2094A19, HMS2096D21, HMS2231D12, HMS3261K20, HMS3369J14, HMS3713D21, Pharmakon1600-01505994, HY-B1096, Tox21_110135, Tox21_110136, Tox21_500459, WLN: 2N2 & VR DQ CO1, 2787AH, NSC759302, SBB057405, AKOS003382844, Tox21_110135_1, API0008512, CCG-204551, CS-4684, DB08989, LP00459, MCULE-4849532738, NSC-759302, NCGC00015397-01, NCGC00015397-03, NCGC00015397-04, NCGC00015397-05, NCGC00015397-07, NCGC00015397-08, NCGC00015397-10, NCGC00023704-03, NCGC00023704-04, NCGC00261144-01, BP-12587, CC-35577, ZB000060, Benzamide,N-diethyl-4-hydroxy-3-methoxy-, SBI-0050444.P002, DB-047788, LS-161392, EU-0100459, FT-0631921, N,N-Diethyl-4-hydroxy-3-methoxybenzamide #, ST45025689, N,N-diethyl-4-hydroxy-3-(methyloxy)benzamide, D04080, E 0137, C-12553, J-017977, SR-01000003047-2, SR-01000003047-5, BRD-K38055836-001-03-9, 2DL, 8060-67-1

ID: 271

InChIKey: BQJRUJTZSGYBEZ-YVQNUNKESA-N
SMILES: CCCC(=O)O[C@@H]1[C@H]([C@]2([C@@H](C=C(C[C@]3([C@H]2C=C(C3=O)C)O)CO)[C@H]4[C@@]1(C4(C)C)OC(=O)CCC)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 37783
synonyms found at PubChem are:
Phorbol 12,13-dibutyrate, PDBU, Phorbol dibutyrate, 37558-16-0, Phorbol 12,13-dibutanoate, Phorbol-12,13-dibutyrate, UNII-67MX82CL58, NSC 622507, CHEMBL27768, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl dibutanoate, CHEBI:17598, 67MX82CL58, Butanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl ester, Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1a-alpha,1b-beta,4a-beta,7a-alpha,7b-alpha,8-alpha,9-beta,9a-alpha))-, SR-05000002331, NSC622507, [butanoyloxy-dihydroxy-(hydroxymethyl)-tetramethyl-oxo-[?]yl] butanoate, Butanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, D02KPV, AC1L1YF2, PHORBOL 12,13-BUTYRATE, BQJRUJTZSGYBEZ-YVQNUNKESA-N, MolPort-023-277-082, [3H]-Phorbol 12,13-Dibutyrate, Phorbol 12,13-Dibutyrate >99%, ZINC4096162, BDBM50057512, HSCI1_000181, MFCD00036783, 4-.beta.-Phorbol 12,13-dibutyrate, AKOS024458006, CCG-208247, NCGC00163607-01, 61557-88-8, Butanoic acid, diester with 1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydro-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropya(3,4)benz(1,2-e)azulen-5-one, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-, LS-46211, B7598, C03634, Phorbol 12,13-dibutyrate, >=98% (TLC), powder, SR-05000002331-2, SR-05000002331-3, BRD-K81365681-001-01-8, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-Decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9,9a-diyl butanoic acid ester, Butanoic acid, (1aR,1bS,4aR,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester

ID: 272

InChIKey: BQKADKWNRWCIJL-UHFFFAOYSA-N
SMILES: CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 65324
synonyms found at PubChem are:
Dobutamine hydrochloride, 49745-95-1, Dobutamine Hcl, Dobutrex, Inotrex, 52663-81-7, Dobutamine (hydrochloride), DL-Dobutamine hydrochloride, Dobutamina clorhidrato [Spanish], EINECS 256-464-1, NSC 299583, LY 46236, S-1000, 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol hydrochloride, (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol hydrochloride, 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, hydrochloride, (+-)-, W-106009, CHEBI:4671, (+/-)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenethylamine hydrochloride, 4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatecholhydrochloride, 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1), SMR000058435, SR-01000075265, DOBUTAMINEHYDROCHLORIDE, Posiject, 4-(2-(4-(4-hydroxyphenyl)butan-2-ylamino)ethyl)benzene-1,2-diol hydrochloride, Dobutrex (TN), Prestwick_741, Dobutamine hydrochloride in dextrose 5%, Dobutamine hydrochloride [USAN:BAN:JAN], 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, hydrochloride, 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol hydrochloride, Dobutamine hydrochloride [USAN:USP:BAN:JAN], AC1Q3F7E, rac Dobutamine Hydrochloride, SCHEMBL41609, MLS000860012, MLS001332503, MLS001332504, MLS002222253, REGID_for_CID_65324, AC1L231V, CHEMBL1200418, CTK1D5917, BQKADKWNRWCIJL-UHFFFAOYSA-N, Dobutamine hydrochloride, >=98%, MolPort-003-940-916, Dobutamine hydrochloride in dextrose 5% in plastic container, HMS1569G05, BCP13026, KS-000016OW, Tox21_500365, BG0171, MFCD00153795, NSC299583, Dobutamine hydrochloride (JP17/USP), AKOS015907731, AN-6582, CCG-220352, CCG-221669, CHM0029387, CS-3099, KS-1050, LP00365, NSC-299583, NCGC00093799-01, NCGC00093799-02, NCGC00261050-01, AC-11653, BC202981, CC-27337, HY-15746, LS-29983, LY-46236, Q711, 49745-95-1 (HCl), AB0017762, AB1009505, AX8016940, KB-289664, LS-175120, TR-036978, D4335, EU-0100365, FT-0625557, FT-0681170, D 0676, D00632, 368D042, A827836, I14-2722, SR-01000075265-1, SR-01000075265-3, SR-01000075265-6, DOBUTAMINE HCL IN DEXTROSE 5% IN PLASTIC CONTAINER, Dobutamine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Dobutamine hydrochloride, European Pharmacopoeia (EP) Reference Standard, (.+-.)-4-[2-[[3-(p-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol hydrochloride, 1, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride, (.+-.)-, 3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenethylamine Hydrochloride, 4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzol-1,2-diolhydrochlorid, 4-[2-[[3-(4-hydroxyphenyl)-1-methyl-propyl]amino]ethyl]benzene-1,2-diol hydrochloride, 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride, 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride, 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol;hydrochloride, Dobutamine hydrochloride, United States Pharmacopeia (USP) Reference Standard, ( inverted exclamation markA)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-|A-phenethylamine hydrochloride; 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride, ( inverted question mark)-4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride, 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, hydrochloride,(+-)-, N-[2-(3,4-dihydroxyphenyl)ethyl]-4-(4-hydroxyphenyl)butan-2-aminium chloride, AKOS015894963, I05-898

ID: 273

InChIKey: BQPRWZCEKZLBHL-UHFFFAOYSA-N
SMILES: COC1=C(C2=C(C=CO2)C3=C1C=CC(=O)O3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4825
synonyms found at PubChem are:
pimpinellin, 131-12-4, 5,6-Dimethoxy-2H-furo[2,3-H]chromen-2-one, Pimpinecilin, CCRIS 4344, 5,6-dimethoxyfuro[2,3-h]chromen-2-one, UNII-D419UK1B4L, CHEBI:8213, D419UK1B4L, 2H-Furo(2,3-h)-1-benzopyran-2-one, 5,6-dimethoxy-, Q-100121, 2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-, Pimpinelline, Spectrum_000417, 6,7-Dimethoxyangelicin, Spectrum2_000720, Spectrum3_001234, Spectrum4_001957, Spectrum5_000769, AC1L1J1E, AC1Q69ME, BSPBio_002708, KBioGR_002397, KBioSS_000897, SPECTRUM300013, DivK1c_001025, 5,6-dimethoxy-2h-furo[2,3-h]-1-benzopyran-2-one, SPBio_000939, MEGxp0_001831, SCHEMBL2255899, CHEMBL1491809, CTK4B7096, HMS503M11, KBio1_001025, KBio2_000897, KBio2_003465, KBio2_006033, KBio3_002208, DTXSID20156831, BQPRWZCEKZLBHL-UHFFFAOYSA-N, MolPort-000-881-658, NINDS_001025, HMS1923E17, ZINC898309, ANW-46778, CCG-40044, AKOS000277261, MCULE-4488948197, SDCCGMLS-0066532.P001, IDI1_001025, NCGC00095242-01, NCGC00095242-02, NCGC00095242-03, 4CN-1212, AJ-24282, AK-57539, AN-43670, AX8031732, KB-244204, LS-188106, ST2405967, TC-135523, FT-0688320, W1283, C09285, 131P124, 5,6-Dimethoxy-2H-furo[2,3-H]chromen-2-one #, SR-05000002492, SR-05000002492-1, BRD-K93197368-001-02-9, BRD-K93197368-001-03-7

ID: 274

InChIKey: BRBKOPJOKNSWSG-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5324
synonyms found at PubChem are:
sulfaguanidine, 57-67-0, Sulphaguanidine, Sulfaguanidin, Guanicil, Sulfaguine, Sulfanilguanidine, Sulfanilylguanidine, Sulfoguanidine, Abiguanil, Guanidan, Sulfaguanil, Sulfentidine, Sulfoguanil, Sulfoguanyl, Aterian, Guamide, Orgaguanidon, Sulfoquanidine, Ganidan, N1-Amidinosulfanilamide, Resulfon, Suganyl, Diacta, Ruocid, Sulgin, N-Guanylsulfanilamide, S-Guanidine, 1-Sulfanilylguanidine, Sulfaguanidinum, Shigatox, Sulfoguenil, Guanidine, sulfanilyl-, p-Aminobenzenesulfonylguanidine, Solfaguanidina, Sulfaguanidina, p-Aminobenzenesulfoguanidide, Sulginum, RP 2275, Benzenesulfonamide, 4-amino-N-(aminoiminomethyl)-, Sulfanilamide, n(sup1)-amidino-, 4-Amino-N-(aminoiminomethyl)benzenesulfonamide, ((p-Aminophenyl)sulfonyl)guanidine, 2-(4-aminophenyl)sulfonylguanidine, ((4-Aminophenyl)sulfonyl)guanidine, 1-((p-Aminophenyl)sulfonyl)guanidine, Solfaguanidina [DCIT], Sulfaguamidine, 4-Amino-N-(diaminomethylene)benzenesulfonamide, A-307, Sulfanilamide, N1-amidino-, N-p-Aminobenzenesulphonylguanidine monohydrate, Sulfaguanidinum [INN-Latin], N(sup 1)-Guanylsulfanilamide, Sulfaguanidina [INN-Spanish], 4-Aminobenzenesulfonylguanidine, UNII-15XQ8043FN, N(sup 1)-Amidinosulfanilamide, 4-amino-N-[amino(imino)methyl]benzenesulfonamide, C7H10N4O2S, 4-amino-N-carbamimidoylbenzenesulfonamide, Emerin (pharmaceutical) (VAN), Sulfaguanidine [INN], N1-Guanylsulfanilamide, Emerin (pharmaceutical), EINECS 200-345-9, NSC 14041, Benzenesulfonamide, 4-amino-N-(diaminomethylene)-, N(sup 1)-(Diaminomethylene)sulfanilamide, AI3-01048, CHEMBL338802, BRBKOPJOKNSWSG-UHFFFAOYSA-N, {[amino(imino)methyl]amino}(4-aminophenyl)dioxo-lambda~6~-sulfane, 15XQ8043FN, 4-Amino-N-guanylbenzenesulfonamide, 1-(4-aminophenyl)sulfonylguanidine, Sulfanilamide, N(sup 1)-amidino-, 2-(4-aminobenzenesulfonyl)guanidine, 61116-95-8, Sulfaguanidine (INN), CAS-57-67-0, NCGC00016252-01, amino[(4-aminophenyl)sulfonyl]carboxamidine, DSSTox_CID_3609, 4-amino-N-(diaminomethylidene)benzenesulfonamide, DSSTox_RID_77107, DSSTox_GSID_23609, [(p-Aminophenyl)sulfonyl]guanidine, [(4-Aminophenyl)sulfonyl]guanidine, 1-[(p-Aminophenyl)sulfonyl]guanidine, Sulfanilyl guanadine, SR-01000000167, N(sup1)-Guanylsulfanilamide, N(sup1)-Amidinosulfanilamide, Sulphanguanidine, Sulfaguanidine [INN:BAN:NF], Gulfanilylguanidine, Ulfaguanidine,(S), Prestwick_429, 2-sulfanilylguanidine, Spectrum_001412, N1-Guanidylsulfanilamide, N-1-Amidinosulfanilamide, AC1Q6TIG, WLN: ZR DSWMYZUM, Prestwick0_000010, Prestwick1_000010, Prestwick2_000010, Prestwick3_000010, Spectrum2_001420, Spectrum3_001456, Spectrum4_000429, Spectrum5_001197, AC1L1K3N, SCHEMBL93639, SCHEMBL93640, 4-aminophenylsulfonylguanidine, BSPBio_000019, BSPBio_002951, KBioGR_000758, KBioSS_001892, MLS000069712, DivK1c_000633, SPECTRUM1501146, SPBio_001500, SPBio_001940, AC1Q4Z09, ARONIS018061, BPBio1_000021, DTXSID1023609, CHEBI:94621, CTK5B2717, CTK8E2965, HMS501P15, KBio1_000633, KBio2_001892, KBio2_004460, KBio2_007028, KBio3_002451, KS-00004ABZ, MolPort-000-900-613, MolPort-002-939-432, NINDS_000633, HMS1568A21, HMS1921J19, HMS2092H05, HMS2095A21, HMS3652J05, HMS3712A21, N1-(Diaminomethylene)sulfanilamide, Pharmakon1600-01501146, 4-Amino-N-amidinobenzenesulfonamide, 1-(4-aminobenzenesulfonyl)guanidine, 2-(4-azanylphenyl)sulfonylguanidine, HY-B1267, KS-000048IC, N-(4-aminobenzenesulfonyl)guanidine, NSC14041, ZINC3873927, Sulfanilamide, N1-amidino- (8CI), Tox21_110329, BDBM50027795, CCG-38973, MFCD00038136, NSC-14041, NSC757861, s4175, SBB006522, STK031666, STK064640, 1-[(4-aminobenzene)sulfonyl]guanidine, AKOS000121440, AKOS000319495, Sulfanilamide, N1-(diaminomethylene)-, Tox21_110329_1, CS-4677, MCULE-9682829853, NE10932, NSC-757861, RP26815, IDI1_000633, SMP1_000283, NCGC00018234-01, NCGC00018234-02, NCGC00018234-03, NCGC00018234-04, NCGC00018234-05, NCGC00018234-07, NCGC00024191-03, NCGC00024191-04, AC-10943, AN-23588, H464, KB-97590, SMR000058191, ST057626, SBI-0051658.P002, SBI-0051658.P003, LS-147738, TR-049555, TX-010926, 4-Amino-N-diaminomethylene-benzenesulfonamide, AB00052220, S0464, D02437, 4-Amino-N-[aminoiminomethyl]- benzenesulfonamide, AB00052220_15, AB00052220_16, 4-amino-N-(amino-imino-methyl)-benzenesulfonamide, Sulfaguanidine, VETRANAL(TM), analytical standard, 1N-amino(imino)methyl-4-amino-1-benzenesulfonamide, I01-9421, SR-01000000167-2, SR-01000000167-3, SR-01000000167-4, W-105451, 4-amino-N-[(E)-amino(imino)methyl]benzenesulfonamide, 4-amino-N-[(Z)-amino(imino)methyl]benzenesulfonamide, Z56758608, 1-Amino-4-(([amino(imino)methyl]amino)sulfonyl)benzene #, A0400/0018450, Sulfaguanidine, European Pharmacopoeia (EP) Reference Standard, 2-[(dioxidosulfanyl)amino]-1,9-dihydro-6H-purin-6-one[sulfaguanine], 4-Amino-N-(aminoiminomethyl)benzenesulfonamide;4-Amino-N-guanylbenzenesulfonamide

ID: 275

InChIKey: BREMLQBSKCSNNH-UHFFFAOYSA-M
SMILES: C[N+]1(CCC(=C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)C.COS(=O)(=O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6126
synonyms found at PubChem are:
DIPHEMANIL METHYLSULFATE, Diphemanil, 62-97-5, Diphemanil metilsulfate, Prantal, Diphenmethanil, Demotil, Nivelon, Nivelona, Talpran, Variton, Diphemanil methosulfate, Diphemanilum, Diphenmanil methylsulfate, Diphemanili metilsulfas, Diphemanil methyl sulfate, Diphenmanil methyl sulfate, Metilsulfate de diphemanil, Metilsulfato de difemanilo, Vagophemanil, Vagophemanil methyl sulfate, ban-guard, Diphenmethanil methyl sulfate, Diphemanil methylsulphate, Ban-Guard (Veterinary), Diphenmethanil methylsulfate, Diphenmanil (methylsulfate), Diphenatil, Prantil, Prentol, UNII-W2ZG23MGYI, Diphemanili metilsulfas [INN-Latin], Prantal (TN), Prantal methylsulfate, Metilsulfate de diphemanil [INN-French], Metilsulfato de difemanilo [INN-Spanish], Diphemanil methylsulfate [INN:BAN], EINECS 200-552-4, 4-(Diphenylmethylene)-1,1-dimethylpiperidinium methyl sulfate, 4-(Diphenylmethylene)-1,1-dimethylpiperidinium methylsulfate, NSC 41725, W2ZG23MGYI, N,N-Dimethyl-4-piperidylidene-1,1-diphenylmethane methylsulfate, p-(alpha-Phenylbenzylidene)-1,1-dimethylpiperidinium methyl sulfate, Diphemanil metilsulfate (INN), CHEBI:59782, Piperidinium, 4-(diphenylmethylene)-1,1-dimethyl-, methyl sulfate, 4-(diphenylmethylidene)-1,1-dimethylpiperidinium methyl sulfate, DSSTox_CID_2948, DSSTox_RID_76802, DSSTox_GSID_22948, Diphemanil metilsulfate [INN], MLS002154192, Diphemanil mesylate, CAS-62-97-5, NCGC00016283-01, SMR001233482, 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium, 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium;methyl sulfate, C20H24N.CH3O4S, Diphemanil methylsulfate [USP], Prestwick_522, Diphemanil methylsulfat, AC1L1LUO, D0OK5Q, SCHEMBL250121, AC1Q22R8, C20H24N.CH4O4S, CHEMBL1200880, DTXSID9022948, N,1-diphenylmethane methylsulfate, MolPort-003-666-719, HMS1568O19, HMS2095O19, HMS2232N20, HMS3372D20, HMS3652M19, HMS3712O19, NSC41725, Tox21_110349, 2381AH, NSC-41725, s4034, AKOS026749921, Tox21_110349_1, CCG-220079, CS-0906, DB00729, NCGC00016283-04, Piperidinium,1-dimethyl-, methyl sulfate, AN-23730, HY-16171, AB0109891, LS-116553, FT-0708684, D06878, W-5134, WLN: T6K DYTJ A1 A1 DUYR&R &WSO&O1, SR-01000841218, SR-01000841218-2, 4-benzhydrylidene-1,1-dimethyl-piperidin-1-ium; methyl sulfate, 4-benzhydrylidene-1,1-dimethylpiperidin-1-ium; methyl sulfate, 4-(diphenylmethylene)-1,1-dimethylpiperidin-1-ium methyl sulfate, P-(alpha.-Phenylbenzylidene)-1,1-dimethylpiperidinium methyl sulfate, p-(.alpha.-Phenylbenzylidene)-1,1-dimethylpiperidinium methyl sulfate

ID: 276

InChIKey: BRJJFBHTDVWTCJ-UHFFFAOYSA-N
SMILES: CCCCC(CC)CN=C(N)NC(=NCCCCCCN=C(N)NC(=NCC(CC)CCCC)N)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 102678
synonyms found at PubChem are:
Alexidine dihydrochloride, 1715-30-6, ALEXIDINE HYDROCHLORIDE, NCGC00094996-01, DSSTox_CID_25881, DSSTox_RID_81197, DSSTox_GSID_45881, 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride, 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2), 1,1'-Hexamethylenebis[5-(2-ethylhexyl)]biguanide dihydrochloride, Alexidine HCl, Prestwick_42, N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide dihydrochloride, CAS-1715-30-6, SR-01000838863, 1,1'-Hexamethylene-bis(5-[2-ethylhexyl]biguanide), C26H56N10.2ClH, 1,1'-Hexamethylenebis(5-(2-ethylhex-1-yl))biguanide dihydrochloride, 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride, EINECS 216-994-6, Alexidine.dihydrochloride, AC1L2TBH, AC1Q3AMY, SCHEMBL292713, SPECTRUM1503074, BIMI8260, CHEMBL554041, DTXSID5045881, CTK8F7635, MolPort-001-761-275, ZX-AFC001164, HMS1570K16, HMS1922C13, 22573-93-9 (Parent), ZX-AT005188, Tox21_111380, 2202AH, CCG-39767, MFCD00082369, OR2503, AKOS024258863, Tox21_111380_1, API0001403, ACM22573939, n,n''''-hexane-1,6-diylbis[n'-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride, N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride, NCGC00094996-02, NCGC00178352-06, Alexidine dihydrochloride, >=95% (HPLC), KB-105233, FT-0661484, J-010730, SR-01000838863-2, SR-01000838863-3, 1-[N'-[6-[[amino-[[N'-(2-ethylhexyl)carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-(2-ethylhexyl)guanidine dihydrochloride, 217969-93-2

ID: 277

InChIKey: BRZANEXCSZCZCI-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N(N1C)C2=CC=CC=C2)NC(=O)C3=CN=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4487
synonyms found at PubChem are:
nifenazone, 2139-47-1, Niapyrin, Nifenazon, Nicazane, Nicodone, Nicofesone, Nicophesone, Nicophezon, Nicotazone, Nikofezon, Phenicazone, Thylin, Nicopyron, Nicoreumal, Nicoron, Nicozone, Nikodon, Anicotinoylantipyrine, Nicotinoylaminoantipyrine, Niprazine, N-Antipyrinylnicotinamide, 4-(Nicotinamido)antipyrine, Nicotinamide, N-antipyrinyl-, 4-(Nicotinoylamino)antipyrine, Nicotinic acid 4-antipyrilamide, C17H16N4O2, Nifenazone [INN:BAN], Nifenazonum [INN-Latin], Nifenazona [INN-Spanish], Nicotinic acid, amidophenyldimethylpyrazolone, UNII-8780F0K71U, 1,5-Dimethyl-4-nicotinamido-2-phenyl-3-pyrazolone, EINECS 218-387-1, 4-Nicotinoylamido-1-phenyl-2,3-dimethyl-5-pyrazolone, 8780F0K71U, BRN 0307504, Nicotinsaeureamidophenyldimethylpyrazolons, NCGC00016605-01, CAS-2139-47-1, Nicotinamide, N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-, DSSTox_CID_25366, DSSTox_RID_80829, DSSTox_GSID_45366, Nicotinsaeureamidophenyldimethylpyrazolons [German], Nifenazone dihydrochloride, 2,3-dimethyl-4-nicotinamido-1-phenyl-3-pyrazolin-5-on, N-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)nicotinamid, N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)pyridine-3-carboxamide, N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)nicotinamide, N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide, SR-01000632824, Nifenazona, Nifenazonum, Dolongan, Reupiron, Nicotinoylantipyrine, Prestwick_582, Spectrum_001575, Nifenazone (JAN/INN), Prestwick0_000225, Prestwick1_000225, Prestwick2_000225, Prestwick3_000225, Spectrum2_000860, Spectrum3_001575, Spectrum4_000848, Spectrum5_000972, N-Nicotinoylaminoantipyrine, AC1L1IA1, Oprea1_385416, SCHEMBL25945, BSPBio_000269, BSPBio_003110, KBioGR_001455, KBioSS_002055, MLS000768954, DivK1c_000546, SPECTRUM1503230, SPBio_000879, SPBio_002190, Nifenazone, analytical standard, BPBio1_000297, CHEMBL1413176, DTXSID7045366, CHEBI:31910, CTK8G1876, HMS501L08, KBio1_000546, KBio2_002055, KBio2_004623, KBio2_007191, KBio3_002610, ZINC57417, BRZANEXCSZCZCI-UHFFFAOYSA-N, MolPort-001-015-123, NINDS_000546, HMS1568N11, HMS1922K15, HMS2095N11, HMS2796P15, HMS3712N11, Pharmakon1600-01503230, Tox21_110519, 2587AH, CCG-40077, NSC758411, STK733507, AKOS001038391, Tox21_110519_1, API0003567, MCULE-1445985424, NSC-758411, IDI1_000546, NCGC00016605-02, NCGC00016605-03, NCGC00016605-04, NCGC00016605-05, NCGC00016605-08, NCGC00095026-01, NCGC00095026-02, NCGC00178289-01, NCGC00178289-02, HY-17475, LS-96379, SMR000433688, ZB002109, SBI-0051796.P002, CS-0009213, D01437, W-2459, AB00052331_09, AB00052331_10, 5-25-14-00153 (Beilstein Handbook Reference), J-014028, SR-01000632824-1, SR-01000632824-3, SR-01000632824-4, BRD-K47407372-001-05-6, BRD-K47407372-001-09-8, BRD-K47407372-001-15-5, N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-nicotinamide, N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)nicotinamide, 3-Pyridinecarboxamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-, N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)nicotinamide #, N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)pyridine-3-carboxamide, N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-pyridinecarboxamide (9CI)

ID: 278

InChIKey: BSFUDCIRZBAPDS-UHFFFAOYSA-N
SMILES: CC1(CC2C1CCC(=C)C(CCC2=O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3860435
synonyms found at PubChem are:
Isokobusone, 5-hydroxy-10,10-dimethyl-6-methylidenebicyclo[7.2.0]undecan-2-one, Spectrum_000706, AC1MYPU9, Spectrum2_001773, Spectrum3_001201, Spectrum4_001459, Spectrum5_000077, BSPBio_002582, KBioGR_001977, KBioSS_001186, SPECTRUM300117, SPBio_001665, CHEMBL1522104, KBio2_001186, KBio2_003754, KBio2_006322, KBio3_002082, DTXSID00397482, CHEBI:108586, MolPort-002-025-510, 24173-72-6, CCG-38422, STL446014, SDCCGMLS-0066540.P001, NCGC00095587-01, NCGC00095587-02, BAS 13118088, 6-Hydroxy-15-nor-7(14)-caryophyllen-3-one, SR-05000002462, SR-05000002462-1, BRD-A97152619-001-03-7, 5-Hydroxy-10,10-dimethyl-6-methylene-bicyclo[7.2.0]undecan-2-one, 5-hydroxy-11,11-dimethyl-4-methylidenebicyclo[7.2.0]undecan-8-one

ID: 279

InChIKey: BSJMWHQBCZFXBR-UHFFFAOYSA-N
SMILES: C1CC(CCC1C2=CC=C(C=C2)Cl)C3=C(C4=CC=CC=C4C(=O)C3=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 74989
synonyms found at PubChem are:
ATOVAQUONE, 95233-18-4, Mepron, Wellvone, Acuvel, 566C80, Mepron (antipneumocystic), Atavaquone, Malarone Pediatric, BW 566C, 566C, Atovaquone (Atavaquone), cis-Atovaquone, DRG-0084, 94015-53-9, UNII-Y883P1Z2LT, C22H19ClO3, Atovaquone [USAN:BAN:INN], BW 566C-80, Mepron (TN), BW-A 566C, HSDB 7083, 2-(trans-4-(p-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, BW-566C-80, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, CRL-8131 & Atovaquone, Atovaquone & Interleukin 12, Y883P1Z2LT, ATO & IL-12, BW-566C, CHEBI:575568, KUCQYCKVKVOKAY-UHFFFAOYSA-N, BW 566C80, 137732-39-9, NCGC00016961-01, 2-(4-(4-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione, CAS-95233-18-4, 2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, DSSTox_CID_2629, trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione, 2-(TRANS-4-(4-CHLOROPHENYL)CYCLOHEXYL)-3-HYDROXY-1,4-NAPHTHALENEDIONE, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-dihydronaphthalene-1,4-dione, DSSTox_RID_76664, DSSTox_GSID_22629, 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-[trans-4-(p-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, 3-(4-(4-chlorophenyl)cyclohexyl)-4-hydroxy-naphthalene-1,2-dione, 3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxy-naphthalene-1,2-dione, 1,4-Naphthalenedione, 2-(4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-, trans-, 1,4-Naphthalenedione, 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-, 2-((1r,4r)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxynaphthalene-1,4-dione, SR-05000001438, pron, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, 566C80 hydroxynaphthoquinone, hydroxynaphthoquinone 566C80, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-naphthalene-1,4-dione, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, hydroxynaphthoquinone, 566C80, 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxynaphthalene-1,4-dione, Atovaquone [USAN:USP:INN:BAN], ATOVAQUONE-D4, Spectrum_001743, SpecPlus_000686, Atovaquone (USP/INN), AC1L2MZG, Prestwick0_000534, Prestwick1_000534, Prestwick2_000534, Prestwick3_000534, Spectrum2_001665, Spectrum3_000991, Spectrum4_001117, Spectrum5_001382, Atovaquone EP Impurity B, D06ZEE, AC1Q6E9K, SCHEMBL21694, SCHEMBL21695, Atovaquone (JAN/USP/INN), BSPBio_000547, BSPBio_002681, KBioGR_001594, KBioSS_002223, MLS002153863, BIDD:GT0849, DivK1c_006782, SCHEMBL637069, SPECTRUM1504210, SPBio_001849, SPBio_002468, 566C80, hydroxynaphthoquinone, BPBio1_000603, CHEMBL222334, CHEMBL519462, GTPL9695, NAP016, SCHEMBL1542719, SCHEMBL1649508, SCHEMBL9975142, SCHEMBL9975229, atovaquone GlaxoSmithKline brand, Atovaquone, >=98% (HPLC), DTXSID7022629, CHEBI:95346, CTK5H7581, KBio1_001726, KBio2_002223, KBio2_004791, KBio2_007359, KBio3_001901, KUCQYCKVKVOKAY-CTYIDZIISA-N, KUCQYCKVKVOKAY-OTVXOJSOSA-N, MolPort-003-666-542, MolPort-006-167-710, BDBM192009, Glaxo Wellcome brand of atovaquone, HMS1569L09, HMS1922F19, HMS2089M14, HMS2093C10, HMS2096L09, HMS2235N08, HMS3369N09, HMS3651N20, HMS3713L09, Pharmakon1600-01504210, GlaxoSmithKline brand of atovaquone, 2-(4-(4'-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, BCP09477, KS-00000FO3, Tox21_110714, CCG-39090, FD7252, NSC759582, s3079, STK636160, trans-2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, ZINC12504271, AKOS005567953, AKOS015895691, AKOS015961933, Tox21_110714_1, ZINC100017856, ZINC100345537, ZINC116473771, ZINC299873031, AN-6439, BW 556C-80, BW-556C-80, CCG-220534, CS-2702, DB01117, MCULE-7318126574, NSC-759582, NCGC00016961-02, NCGC00016961-03, NCGC00016961-04, NCGC00016961-06, NCGC00016961-07, NCGC00095113-01, NCGC00095113-02, AC-30251, AS-12809, BC208879, HY-13832, SC-15688, SC-21393, SMR001233220, SBI-0052893.P002, AB0012456, AB0107187, AB0211463, KB-270797, LS-178256, TX-010638, AB00513855, FT-0081084, FT-0602868, C06835, D00236, J90007, 78668-EP2307343A1, AB00053222-03, AB00053222_04, AB00053222_05, 233A184, I06-0872, SR-05000001438-1, SR-05000001438-2, SR-05000001438-4, SR-05000001438-5, 2-(4-(4-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-nap, Z1541632806, 2-[4-(4-chlorophenyl)cyclohexy]-3-hydroxy-1,4-naphthoquinone, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-napthoquinone, 2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1.4-naphthoquinone, 2-Hydroxy-3-[4-(4-chlorophenyl)cyclohexyl]-1,4-naphthoquinone, 3-[4-(p-chlorophenyl)cyclohexyl]-4-hydroxy-1,2-naphthoquinone, 1,4-Naphthalenedione, 2-(4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-, 2-[4-(4-chlorophenyl)-cyclohexyl]-3-hydroxy-1,4-naphthoquinone, 2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxynaphthoquinone, trans-, 3-[4-(4-Chlorophenyl)cyclohexyl]-4-hydroxy-1,2-naphthalenedione, Cis-2-[4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, 1,4-Naphthalenedione, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy, 1,4-naphthalenedione,2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-

ID: 280

InChIKey: BTCSSZJGUNDROE-UHFFFAOYSA-N
SMILES: C(CC(=O)O)CN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 119
synonyms found at PubChem are:
4-aminobutyric acid, 4-Aminobutanoic acid, GABA, gamma-aminobutyric acid, 56-12-2, Piperidic acid, Piperidinic acid, Aminalon, Gaballon, Gammalon, Mielogen, butanoic acid, 4-amino-, Gammalone, Mielomade, Gamarex, Gammasol, Gammar, Reanal, gamma-amino-n-butyric acid, Immu-G, gamma-Aminobutanoic acid, Butyric acid, 4-amino-, Gamastan, Gammagee, Gamulin, 4-aminobutyrate, omega-Aminobutyric acid, .gamma.-Aminobutyric acid, 3-Carboxypropylamine, 4-aminobutanoate, gamma-Aminobuttersaeure, 4-amino-butanoic acid, gamma-Amino butyric acid, gamma-aminobutyrate, 4-amino butyric acid, 4-Amino-butyric acid, DF 468, gamma Aminobutyric acid, CCRIS 3721, GAMMA-AMINO-BUTANOIC ACID, UNII-2ACZ6IPC6I, Aminobutanoic acid, NSC 27418, 4Abu, EPA Pesticide Chemical Code 030802, Gamma-aminobutyric acid [JAN], gamma-Aminobuttersaeure [German], AI3-26812, gamma-Aminobutryic acid, GAMMA(AMINO)-BUTYRIC ACID, 4-amino-n-butyric acid, 4-NH2-but, 4-NH3-but, Acide amino-4- butyrique [French], CHEMBL96, EINECS 200-258-6, 2ACZ6IPC6I, .gamma.-Aminobutanoic acid, [3H]GABA, MLS000028505, gamma-Aminobutyric acid (JAN), CHEBI:16865, BTCSSZJGUNDROE-UHFFFAOYSA-N, Butanoic acid, 4-amino- (9CI), NSC27418, NSC32044, NSC45460, NSC51295, 4-Aminobutylate, Butyric acid, 4-amino- (7CI,8CI), NCGC00015043-07, Aminalone, SMR000058285, 4-AMINO-BUTYRATE, WLN: Z3VQ, 20-79-1, BUTANOIC ACID,4-AMINO, g-Aminobutyric acid, Chemical Name: .gamma.-Aminobutanoic acid, SR-01000075618, Acide amino-4- butyrique, Immuglobin, Piperidinate, w-Aminobutyrate, 4-Aminobutyric, Gamma aminobutyrate, omega-Aminobutyrate, Gammalon (TN), a-Aminobutyric acid, w-Aminobutyric acid, gamma-Aminobuttersaure, gam.-Aminobutyric acid, Spectrum_000049, Tocris-0344, Aminobutyric acid,-4-, Butanoicacid, 4-amino-, Opera_ID_1152, Spectrum2_001208, Spectrum3_001385, Spectrum4_000809, Spectrum5_001425, Lopac-A-2129, Vigabatrin EP Impurity D, .omega.-Aminobutyric acid, cid_119, ACMC-1CAQ1, Biomol-NT_000230, bmse000340, bmse000820, bmse000871, D0C9XA, D0D3ID, .gamma.-Amino-butyric acid, AC1L18IR, AC1Q54DP, SCHEMBL4878, DSSTox_CID_15106, DSSTox_RID_79238, DSSTox_GSID_35106, Globulin, immune human serum, Lopac0_000005, Oprea1_584567, BSPBio_002970, Gamma-Aminobutyric Acid,(S), KBioGR_001297, KBioSS_000429, KSC269S7N, ARONIS27190, DivK1c_000616, NH2-(CH2)3-COOH, SPECTRUM1500678, .gamma.-Amino-N-butyric acid, SPBio_000996, GTPL1067, GTPL5410, SGCUT00121, DTXSID6035106, 5959-35-3 (hydrochloride), BDBM24183, CTK1G9976, HMS501O18, KBio1_000616, KBio2_000429, KBio2_002997, KBio2_005565, KBio3_002190, gamma-Aminobutyric acid, >=99%, MolPort-000-146-216, NINDS_000616, HMS1921C06, HMS2232P09, HMS3260A11, Pharmakon1600-01500678, DL-gamma-AMINO-n-BUTYRIC ACID, GABA (4-Amino-n-butyric acid ), STR01523, to_000021, ZINC1532620, 4-amino-n-[2,3-3H]butyric acid, Tox21_110071, Tox21_500005, 4-Aminobutyric acid, 97% 100g, ANW-13573, BBL008590, CCG-38515, GSK683699, LMFA01100039, MFCD00008226, NSC-27418, NSC-32044, NSC-45460, NSC-51295, NSC757426, PDSP1_001275, PDSP2_001259, s4700, SBB028179, STK301748, AKOS000119660, CS-W020704, DB02530, KS-5273, LP00005, MCULE-7613134021, NSC-757426, RP18806, RTR-019733, TRA0094659, CAS-56-12-2, IDI1_000616, KS-000048O9, 6610-05-5 (mono-hydrochloride salt), NCGC00015043-01, NCGC00015043-02, NCGC00015043-03, NCGC00015043-04, NCGC00015043-05, NCGC00015043-06, NCGC00015043-08, NCGC00015043-09, NCGC00015043-10, NCGC00024546-01, NCGC00024546-02, NCGC00024546-03, NCGC00024546-04, NCGC00024546-05, NCGC00024546-06, NCGC00260690-01, AJ-26795, AN-24434, BC204189, BP-21452, BR-43987, KB-62456, LS-47805, SC-10045, TL806167, gamma-Aminobutyric acid, BioXtra, >=99%, SBI-0049994.P003, AB1003088, gamma-Aminobutyric acid, analytical standard, ST2411110, TL8006100, TR-019733, 70582-09-1 (calcium salt (2:1)), A0282, AM20100372, EU-0100005, FT-0617569, ST45061580, A 2129, C00334, D00058, M-7233, 13511-EP2269989A1, 13511-EP2272537A2, 13511-EP2275401A1, 13511-EP2292222A1, 13511-EP2298766A1, 13511-EP2298776A1, 13511-EP2308875A1, 13511-EP2314571A2, 13511-EP2316836A1, 33777-EP2286811A1, 33777-EP2295055A2, 33777-EP2311453A1, AB00052155_12, 178648-EP2269992A1, 178648-EP2270002A1, 178648-EP2275102A1, 178648-EP2277865A1, L000262, I04-0182, I04-1117, SR-01000075618-1, SR-01000075618-3, SR-01000075618-6, SR-01000075618-7, BRD-K77245796-001-19-2, BUTANOIC ACID,4-AMINO 4-AMINO,BUTYRIC ACID, F2191-0196, Z955123658, C5C3DC27-C105-4D18-8A52-F51978B32D24, gamma-Aminobutyric acid, certified reference material, TraceCERT(R), InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7, Vigabatrin impurity D, European Pharmacopoeia (EP) Reference Standard, gamma-Aminobutyric acid, United States Pharmacopeia (USP) Reference Standard, 3131-86-0, 4-ammoniobutanoate, 4-azaniumylbutanoate, 4euo, gamma-amino-N-butyrate, g-amino-n-butyric acid, 3ip9, D04QAC, CHEBI:59888, gamma-aminobutyric acid zwitterion, CJ-05261, A830919

ID: 281

InChIKey: BTFMCMVEUCGQDX-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCC(CC4)CCO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 19675
synonyms found at PubChem are:
PIPERACETAZINE, Quide, Psymod, 3819-00-9, Piperazetazina [DCIT], PC-1421, UNII-KL6248WNW4, Piperacetazinum [INN-Latin], Piperacetazina [INN-Spanish], SC 9794, EINECS 223-312-0, KL6248WNW4, BTFMCMVEUCGQDX-UHFFFAOYSA-N, 10-(3-(4-(2-Hydroxyethyl)piperidino)propyl)phenothiazin-2-yl methyl ketone, NCGC00016642-01, CAS-3819-00-9, 2-Acetyl-10-(3-(4-(beta-hydroxyethyl)piperidino)propyl)phenothiazine, DSSTox_CID_3481, 1-[10-[3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl]phenothiazin-2-yl]ethanone, Ketone, 10-(3-(4-(2-hydroxyethyl)piperidino)propyl)phenothiazin-2-yl methyl, 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperidinyl)propyl)-10H-phenothiazin-2-yl)ethanone, DSSTox_RID_77047, Ethanone, 1-(10-(3-(4-(2-hydroxyethyl)-1-piperidinyl)propyl)-10H-phenothiazin-2-yl)-, DSSTox_GSID_23481, Piperacetazinum, Piperacetazina, Piperazetazina, Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-10H-phenothiazin-2-yl]-, Piperacetazine [USAN:INN], Piperacetazine [USAN:USP:INN], 1-(10-{3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl}-10H-phenothiazin-2-yl)ethanone, Quide (TN), Prestwick0_001048, Prestwick1_001048, Prestwick2_001048, Prestwick3_001048, D0AO6B, AC1L2EM8, CHEMBL1584, Piperacetazine (USAN/INN), BSPBio_000976, MLS002154124, SCHEMBL148569, SPBio_002908, BPBio1_001074, DTXSID7023481, CHEBI:92293, MolPort-006-115-728, HMS1571A18, HMS2098A18, HMS2230G17, HMS3369H17, HMS3715A18, Pharmakon1600-01503874, ZINC538186, HY-B1152, Tox21_110540, NSC760067, AKOS030526141, Tox21_110540_1, API0009003, CCG-213229, CS-4756, NSC-760067, NCGC00016642-02, NCGC00016642-04, NCGC00179353-01, LS-87220, SMR001233431, AB00514021, D02679, EN300-221562, AB00514021_06, 819P009, SR-01000841199, SR-01000841199-2, Z2065671295, 2-Acetyl-10-(3-(4-(.beta.-hydroxyethyl)piperidino)propyl)phenothiazine, 1-(10-(3-[4-(2-Hydroxyethyl)-1-piperidinyl]propyl)-10H-phenothiazin-2-yl)ethanone #, 1-(10-{3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-2-phenothiazinyl]ethanone, 1-(10-{3-[4-(2-HYDROXYETHYL)PIPERIDIN-1-YL]PROPYL}-10H-PHENOTHIAZIN-2-YL)ETHAN-1-ONE

ID: 282

InChIKey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
SMILES: CC[C@H](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 160355
synonyms found at PubChem are:
roscovitine, Seliciclib, 186692-46-6, R-Roscovitine, (R)-roscovitine, CYC202, CYC-202, CYC 202, Rosco, 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, UNII-0ES1C2KQ94, NSC 701554, AL-39256, InSolution™ Roscovitine, CHEMBL14762, 0ES1C2KQ94, BMK1-E12, CHEBI:45307, Roscovitine (Seliciclib,CYC202), (2r)-2-{[6-(benzylamino)-9-isopropyl-9h-purin-2-yl]amino}-1-butanol, NSC701554, NSC-701554, (2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol, (2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol, (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol, (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol, M02443, RRC, C19H26N6O, 6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine, (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, Seliciclib [INN], CYC202, Seliciclib, R-roscovitine, Roscovitine, 1unl, 3ddq, (2R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol, 2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-(R)-1-butanol, Roscovitine/CYC202, 2a4l, BiomolKI_000048, 1-Butanol, (2R)-, ROSCOVITINE(Seliciclib), BiomolKI2_000054, D02TIZ, D05ADP, AC1L4NH4, AC1Q4VI5, CBiol_002016, Lopac0_001102, SCHEMBL94728, BSPBio_001078, KBioGR_000418, KBioSS_000418, MLS006011028, BDBM7533, cid_160355, GTPL6035, Roscovitine, >=98% (TLC), BCBcMAP01_000013, CTK4D9313, KBio2_000418, KBio2_002986, KBio2_005554, KBio3_000795, KBio3_000796, AOB2095, DTXSID20171928, EX-A052, BTIHMVBBUGXLCJ-OAHLLOKOSA-N, MolPort-003-959-463, BCPP000087, Bio1_000302, Bio1_000791, Bio1_001280, Bio2_000379, Bio2_000859, CC205, HMS1362F19, HMS1792F19, HMS1990F19, HMS3229N13, HMS3403F19, BCP01760, Roscovitine (Seliciclib, CYC202), ZINC1649340, ABP000228, BS0304, GP3424, HSCI1_000092, MFCD02266401, s1153, AKOS005146319, AC-2416, AN-1311, CCG-100652, RL02372, IDI1_002134, SMP1_000266, 2,6,9-Trisubstituted purine deriv. 28, NCGC00094374-01, NCGC00094374-02, NCGC00094374-03, NCGC00094374-04, NCGC00094374-05, AJ-28787, BC683378, HY-30237, KB-60358, NCI60_036420, SC-85946, SMR004702823, AB1010069, CYC202, Seliciclib, 186692-46-6, LS-182554, RT-015440, FT-0674460, X7381, K00020, S-7720, 692R466, J-011999, J-524224, BRD-K07691486-001-03-1, BRD-K07691486-001-05-6, UNII-AIR55KO85E component BTIHMVBBUGXLCJ-OAHLLOKOSA-N, (2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]-1-butanol, (2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol, (2R)-2-{[6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl]amino}butan-1-ol, (R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol, 1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2- yl)amino)-, (2R)-, 1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2- yl)amino)-, (R)-, 1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (2R)-, 1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (R)-, 1-Butanol,2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-, 2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]- 9H-purin-2-yl]amino]-(R)-1-butanol, 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; 6-(Benzylamino) -2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine, Seliciclib|||CYC-202|||(2R)-2-[[6-(Benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol

ID: 283

InChIKey: BTVYAVLJYUREDC-VQMBCJHASA-N
SMILES: CC1=C(O[C@@H]2[C@H]1[C@]3(CCC4[C@H](C3C2)CC[C@@H]5[C@@]4(CC[C@@H](C5)OC(=O)C)C)C)CC[C@@H](C)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 98042581
synonyms found at PubChem are:
PSEUDO-TIGOGENIN ACETATE

ID: 284

InChIKey: BTXNYTINYBABQR-UHFFFAOYSA-N
SMILES: CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281051
synonyms found at PubChem are:
hypericin, 548-04-9, Hypericum red, Cyclosan, hipericina, hypericine, Hyperizin, 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione, Cyclo-Werol, Hypericum Extract, VIMRxyn, UNII-7V2F1075HD, C30H16O8, EINECS 208-941-0, NSC407313, Hypericin & Visible light, NSC 407313, NSC 622946, CHEBI:5835, CHEMBL286494, (component of) Hypericum spp (st. John's wort), 7V2F1075HD, NSC622946, Cyclo werrol, 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone, 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethyl-mesonapthtodianthron, 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione, hexahydroxy(dimethyl)[?]dione, Q-100618, 1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione, Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-, Mycoporphyrin, Vimr, Cyclo-werrol, CCRIS 8166, Hypericin?, BiomolKI_000032, BiomolKI2_000040, Hypericin, 98% 25mg, SCHEMBL3182, BIDD:PXR0084, BMK1-D8, SCHEMBL10262695, BIH1002, DTXSID40203270, BTXNYTINYBABQR-UHFFFAOYSA-N, MolPort-003-983-595, ZX-AFC000188, Hypericin from Hypericum perforatum, BCP10403, HY-N0453, ZINC3780340, BDBM50060874, CCG-36081, CH-268, GE3282, HSCI1_000202, LMPK13040001, MFCD00016683, AKOS015895658, AC-6048, CS-5687, DB13014, EBD2048972, MCULE-7319800130, NSC-407313, NSC-622946, NCGC00162454-01, NCGC00163378-01, NCGC00163378-02, 4CN-1297, AJ-45583, AN-45822, CC-29451, NCI60_003879, NCI60_006799, SC-18495, NCGC00163378-03!, LS-175574, FT-0627169, N2739, C07606, 33919-EP2275420A1, 33919-EP2295055A2, 33919-EP2295416A2, 33919-EP2298748A2, 33919-EP2298764A1, 33919-EP2298765A1, 33919-EP2305642A2, 33919-EP2311453A1, 548H049, C-22963, SR-05000002344, Hypericin from Hypericum perforatum, ~95% (HPLC), Hypericin, primary pharmaceutical reference standard, SR-05000002344-2, BRD-K29673530-001-03-9, 3,4,6,7,13,14-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-1,8-dione, 3,4,7,8,13,14-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-1,6-dione, 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione, 9CI, 1,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro [1,10,9,8-opqra]perylene-7,14-dione P-conformer, InChI=1/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H, Phenanthro[1,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-, stereoisomer

ID: 285

InChIKey: BUCORZSTKDOEKQ-UHFFFAOYSA-N
SMILES: CN=C1CN(C(=C2C=C(C=CC2=N1)Cl)C3=CC=CC=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2712
synonyms found at PubChem are:
chlordiazepoxide, Librium, Methaminodiazepoxide, Chlorodiazepoxide, 58-25-3, Chlordiazepoxid, Chlozepid, Elenium, Chlordiazepoxidum, Chloridiazepide, Helogaphen, Librelease, Balance, Clopoxide, Control, Decacil, Ifibrium, Kalmocaps, Librinin, Libritabs, Menrium, Mesural, Mildmen, Napoton, Psicosan, Radepur, Risolid, Silibrin, Tropium, Viopsicol, Lygen, Multum, Zetran, Eden, Chlordiazachel, Disarim, Sonimen, Zeisin, Clordiazepossido, Chloradiazepoxide, Chlordiazepoxydum, Eden-psich, A-Poxide, Clordiazepoxido, Chloridazepoxide, 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide, Balance (pharmaceutical), Chlordiazepoxide Hcl, Clordiazepossido [Italian], 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, Chlordiazepoxidum [INN-Latin], Clordiazepoxido [INN-Spanish], Abboxide, Librax, Napton, Chloridiazepoxide, Novo-Poxide, UNII-6RZ6XEZ3CR, Libritabs (TN), Apo-Chlordiazepoxide, Chlordiazepoxide Base, HSDB 3028, EINECS 200-371-0, 6RZ6XEZ3CR, CHEMBL451, MENRIUM 5-4, Chlordiazepoxide [USAN:INN:BAN:JAN], MENRIUM 10-4, DEA No. 2744, 7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide, 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine, 3H-1,4-Benzodiazepine, 7-chloro-2-(methylamino)-5-phenyl-, 4-oxide, 7-Chlor-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxid [German], 7-Cloro-2-metilamino-5-fenil-3H-1,4-benzodiazepina 4-ossido [Italian], Azepoxide-d5, 7-Chlor-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxid, 7-Cloro-2-metilamino-5-fenil-3H-1,4-benzodiazepina 4-ossido, Librium (TN), DSSTox_CID_26022, DSSTox_RID_81295, DSSTox_GSID_46022, 7-Chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide, 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl, 4-oxide, 3H-1,4-benzodiazepin-2-amine,7-chloro-N-methyl-5-phenyl-,4-oxide, 7-chloro-2-(methylamino)-5-phenyl-3H-benzo[e][1,4]diazepine 4-oxide, CAS-58-25-3, SMR000469226, 7-chloro-N-methyl-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-amine, chlordiazepoxide-hcl, Novapam (TN), Tropium (TN), Librinin|||Silibrin, Chlordiazepoxide [USP:INN:BAN:JAN], Chlordiazep-oxide HCl, AC1L1EAN, Spectrum2_001157, Spectrum4_000578, Spectrum5_001623, D06BEP, SCHEMBL18474, KBioGR_001016, MLS001066622, MLS001424220, MLS003899195, C16H14ClN3.H2O, DivK1c_000995, SCHEMBL145243, SPBio_001113, CHEBI:3611, GTPL3370, DTXSID4046022, CHEBI:94781, HMS503G11, KBio1_000995, ANTSCNMPPGJYLG-UHFFFAOYSA-N, MolPort-002-051-367, NINDS_000995, HMS2052C19, HMS2231M10, HMS3373M10, HMS3394C19, Chlordiazepoxide (JP15/USP/INN), Chlordiazepoxide (JP17/USP/INN), Tox21_111567, Tox21_111568, BBL010791, BDBM50007664, STK597142, ZINC19632917, AKOS005518509, AKOS015963131, AB06298, API0000465, CCG-101136, DB00475, NC00386, Chlordiazepoxide 1.0 mg/ml in Methanol, IDI1_000995, NCGC00246347-01, AC-13012, AN-23598, CPD000469226, LS-34063, SAM001246815, LS-168455, FT-0631257, D00267, AB00053219-06, I06-0193, W-105404, 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2amine-4-oxide, (1E,4E)-7-chloro-2-(methylamino)-5-phenyl-3H-benzo[e][1,4]diazepine 4-oxide, (7-CHLORO-4-OXY-5-PHENYL-3H-BENZO[E][1,4]DIAZEPIN-2-YL)-METHYL-AMINE

ID: 286

InChIKey: BUYMVQAILCEWRR-UHFFFAOYSA-N
SMILES: COP(=O)(OC)OC(C(Cl)(Cl)Br)Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4420
synonyms found at PubChem are:
naled, Dibrom, Bromchlophos, Bromex, 300-76-5, Ortho-Dibrom, Dibromfos, Alvora, Fosbrom, Flibol Ex, Bromex 50, Arthodibrom, Orthodibromo, Bromex (insecticide), Nikabrom, Hibrom, 1,2-Dibromo-2,2-dichloroethyl dimethyl phosphate, Naledu [Polish], (1,2-Dibromo-2,2-dichloroethyl) dimethyl phosphate, Caswell No. 586, ENT 24988, Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester, Ortho 4355, Naled [ANSI:BSI:ISO], OMS 75, HSDB 1148, EINECS 206-098-3, (+/-)-Naled, Dimethyl 1,2-dibromo-2,2-dichloroethyl phosphate, Dimethyl-1,2-dibromo-2,2-dichloroethyl phosphate, EPA Pesticide Chemical Code 034401, RE-4355, BRN 2049930, Ethanol, 1,2-dibromo-2,2-dichloro-, dimethyl phosphate, O,O-Dimethyl O-2,2-dichloro-1,2-dibromoethyl phosphate, AI3-24988, CHEBI:38729, BRP, O,O-Dimethyl-O-(1,2-dibromo-2,2-dichloroethyl)phosphate, O,O-Dimethyl-O-(1,2-dibrom-2,2-dichlor-aethyl)-phosphat [German], O-(1,2-Dibrom-2,2-dichlor-aethyl)-O,O-dimethyl-phosphat [German], O-(1,2-Dibromo-2,2-dicloro-etil)-O,O-dimetil-fosfato [Italian], O-(1,2-Dibroom-2,2-dichloor-ethyl)-O,O-dimethyl-fosfaat [Dutch], DSSTox_CID_4209, Fosforan O-1,2-dwubromo-2,2-dwuchloroetylo-O,O-dwumetylowy [Polish], Phosphate de O,O-dimethyle et de O-(1,2-dibromo-2,2-dichlorethyle) [French], DSSTox_RID_77328, DSSTox_GSID_24209, fosforan, o-(1,2-Dibromo-2,2-dichloroethyl)-o,o-dimethyl phosphate, Naledu, CAS-300-76-5, C4H7Br2Cl2O4P, Trumpet, Dibrom®, o-Dibrom 8E, Spectrum_001775, SpecPlus_000358, AC1Q3GDI, Spectrum2_001858, Spectrum3_000809, Spectrum4_000649, Spectrum5_001928, AC1L1I4M, BSPBio_002277, KBioGR_000997, KBioSS_002256, DivK1c_006454, SCHEMBL117764, SPBio_001676, CHEMBL1887067, DTXSID1024209, O-(1,2-Dibromo-2,2-dicloro-etil)-O,O-dimetil-fosfato, BUYMVQAILCEWRR-UHFFFAOYSA-, CTK8E2551, KBio1_001398, KBio2_002255, KBio2_004823, KBio2_007391, KBio3_001777, O,O-Dimethyl-O-(1,2-dibrom-2,2-dichlor-aethyl)-phosphat, O-(1,2-Dibrom-2,2-dichlor-aethyl)-O,O-dimethyl-phosphat, O-(1,2-Dibroom-2,2-dichloor-ethyl)-O,O-dimethyl-fosfaat, BUYMVQAILCEWRR-UHFFFAOYSA-N, Fosforan O-1,2-dwubromo-2,2-dwuchloroetylo-O,O-dwumetylowy, Phosphoric Acid 1,2-Dibromo-2,2-dichloroethyl Dimethyl Ester, Tox21_201641, Tox21_300845, ACM300765, CCG-39396, Phosphate de O,O-dimethyle et de O-(1,2-dibromo-2,2-dichlorethyle), AKOS015903004, Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester (8CI)(9CI), RE 4355, NCGC00163711-01, NCGC00163711-02, NCGC00163711-03, NCGC00163711-04, NCGC00163711-05, NCGC00163711-06, NCGC00254748-01, NCGC00259190-01, LS-107607, TR-012972, FT-0672590, C18749, Dibrom(R), PESTANAL(R), analytical standard, 57306-EP2298769A1, 57306-EP2308878A2, C-44445, J-017762, I14-18731, 1,2-Dibromo-2,2-dichloroethyl dimethyl phosphatic acid, Naled (Dibrom) Solution, 100 microg/mL in Acetonitrile, Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester (8CI), InChI=1/C4H7Br2Cl2O4P/c1-10-13(9,11-2)12-3(5)4(6,7)8/h3H,1-2H3, 53095-31-1

ID: 287

InChIKey: BVGLIYRKPOITBQ-ANPZCEIESA-N
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C.C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 15232
synonyms found at PubChem are:
1538-09-6, Debecillin, Pendepon, Penduran, BENZATHINE PENICILLIN G, Benzacillin, Diaminocillina, Dibencillin, Extenicilline, Lentocillin, Longacilina, Benzapen, Cillenta, Debecylina, Dibencil, Durabiotic, Duropenin, Leomypen, Longicil, Moldamin, Penadur, Penditan, Penidure, Wycillina, Neolin, Bica-penicillin, Dura-penita, Bicillin I, Bicillin 1, Diamine penicillin, Penadur L-A, Pen-Di-Ben, Megacillin suspension, Benzathin penicillin G, Penicillin G, benzathine, UNII-SSZ1S4I0US, Benzylpenicillinum benzathinum, Benzylpenicillinum benzathinicum, NCI-C56100, Benzilpenicillina benzatinica [DCIT], EINECS 216-260-5, SSZ1S4I0US, Dibenzylethylenediamine-di-penicillin G, Benzatina bencilpenicilina [INN-Spanish], Benzathine benzylpenicilline [INN-French], Benzathini benzylpenicillinum [INN-Latin], Penicillin G benzathine anhydrous [USAN], Benzylpenicillin benzathine salt, Benzathine penicillin G tetrahydrate, N,N'-Dibenzylethylenediamine salt of benzylpenicillin, C16H20N2.2C16H18N2O4S, Penicillin G, compd. with N,N'-dibenzylethylenediamine (2:1), Ethylenediamine, N,N'-dibenzyl-, compd. with penicillin G (1:2), N,N'-Dibenzylethylenediamine, compounded with penicillin G (1:2), DSSTox_CID_27781, DSSTox_RID_82557, DSSTox_GSID_47804, 1,2-Ethanediamine, N,N'-bis(phenylmethyl)-, bis((2S,5R,6R)-3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate), Penicillin G benzathine salt with 0.2% Polysorbate 80, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenylacetamido)-, compd. with N,N'-dibenzylethylenediamine (2:1), 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2S,5R,6R)-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1), Ethylenediamine, N,N'-dibenzyl-, bis(3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate), CAS-1538-09-6, Benzilpenicillina benzatinica, N,N'-dibenzylethane-1,2-diamine;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, penicillin-G benzathine, D0U4YG, SCHEMBL34089, AC1L25G8, CHEMBL3182097, DTXSID2047804, Benzathine benzylpenicillin [INN], MolPort-006-113-375, BCP19762, Tox21_111587, Tox21_111587_1, NCGC00021679-07, P691, LS-185074, FT-0770685, X2930, Penicillin G benzathine salt with 1% Lecithin, 538B096, Q-200700, W-108033, Benzathine penicillin, Antibiotic for Culture Media Use Only, 12705-12-3, 141676-23-5, 2792-46-3, 5968-77-4, 77087-98-0, 8048-79-1, N,N'-dibenzylethane-1,2-diamine; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, N1,N2-dibenzylethane-1,2-diamine bis((2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate), Benzatina bencilpenicilina, Benzathine benzylpenicilline, Benzathini benzylpenicillinum, CHEBI:51352, Epitope ID:224559, DB09323, N,N'-dibenzylethane-1,2-diaminium bis{2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate}

ID: 288

InChIKey: BWFSBUVPIAIXKJ-QHHAFSJGSA-N
SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6438092
synonyms found at PubChem are:
Homobutein, 34000-39-0, 2',4,4'-Trihydroxy-3-methoxychalcone, Acrylophenone, 2',4'-dihydroxy-3-(p-hydroxy-m-methoxyphenyl)-, (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one, 1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one, 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-, 3-O-Methylbutein, EINECS 251-782-7, 4,2',4'-Trihydroxy-3-methoxychalcone, (E)-2',4,4'-Trihydroxy-3-methoxychalcone, AC1O5P0X, SCHEMBL633521, CHEMBL144686, BWFSBUVPIAIXKJ-QHHAFSJGSA-N, ZINC4252597, LMPK12120112, CCG-208390, ACM34000390, NCGC00163564-01, LS-123870, ST50331410, 4,2',4'-Trihydroxy-3-methoxy-trans-chalcone, SR-05000002283, SR-05000002283-2, (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one, 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-, (2E)-, 21583-31-3

ID: 289

InChIKey: BWHLPLXXIDYSNW-UHFFFAOYSA-N
SMILES: C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 84003
synonyms found at PubChem are:
Ketorolac tromethamine, Ketorolac tris salt, 74103-07-4, Toradol, Acular, Acular LS, Acular PF, Acuvail, Syntex, Ketorolac (tromethamine salt), Ketorolac trometamol, SPRIX, Acular Preservative Free, Ketorolac tromethamine salt, Ketorolac (Toradol), Lixidol, Dolac, 2-amino-2-(hydroxymethyl)propane-1,3-diol 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, CPD000058461, Acular (TN), (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Q-201269, C19H24N2O6, Godek, (+/-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt, CHEBI:6130, 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro, (+-)-, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, SMR000058461, Tromethamine ketorolac, SR-01000075948, Toratex, Droal, Ketorolac Rinse, Ketorolac tromethamine [USAN], Tora-Dol, Ketorolac tromethamine [USAN:USP], 2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, C15H13NO3.C4H11NO3, BPPC, ketorolac; tris buffer, Spectrum_001578, Ketorolac tromethamine ophthalmic solution, Prestwick0_000929, Prestwick1_000929, Prestwick2_000929, Prestwick3_000929, Spectrum2_001598, Spectrum3_001975, Spectrum4_000215, Spectrum5_001273, AC1L36LM, SCHEMBL5036, Lopac0_000676, BSPBio_000838, BSPBio_003575, KBioGR_000849, KBioSS_002058, Ketorolac tromethamine (USP), MLS000069689, MLS001401455, MLS002222310, DivK1c_000836, SPECTRUM1503925, SPBio_001596, SPBio_003017, BPBio1_000922, CHEMBL1201124, CTK8G0438, HMS502J18, KBio1_000836, KBio2_002058, KBio2_004626, KBio2_007194, KBio3_002953, KS-00000XLJ, ROX-828, ROX-888, BWHLPLXXIDYSNW-UHFFFAOYSA-N, MolPort-003-666-507, NINDS_000836, Acular;Ketorolac tris salt;Toradol, HMS1570J20, HMS1922K22, HMS2051P06, HMS2093M05, HMS2097J20, HMS2235N13, HMS3262G13, HMS3373M06, HMS3393P06, HMS3655E15, HMS3714J20, Pharmakon1600-01503925, BCP02917, HY-B0138, (+/-)-Ketorolac Tromethamine Salt, Tox21_500676, ABP001027, BG0547, CCG-39376, CK0012, MFCD00887595, NSC758637, AKOS024386301, API0003085, BCP9000811, CCG-101006, CS-1933, LP00676, NC00256, NSC-758637, RL04801, IDI1_000836, NCGC00016159-02, NCGC00016159-03, NCGC00016159-04, NCGC00094036-01, NCGC00094036-02, NCGC00094036-03, NCGC00261361-01, 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro, (+/-)-, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol(1:1), AN-37166, AS-15193, O440, SAM001246596, BCP0726000301, Ketorolac tris salt, >=99%, crystalline, AB2000191, LS-139095, EU-0100676, FT-0630829, K0053, ST51037313, D00813, K 1136, 103K074, C-21261, SR-01000946595, SR-01000075948-1, SR-01000075948-6, SR-01000075948-8, SR-01000946595-1, F0001-2390, Ketorolac Trometamol 1.0 mg/ml in Methanol (as free acid), Ketorolac trometamol, European Pharmacopoeia (EP) Reference Standard, Ketorolac Tromethamine, United States Pharmacopeia (USP) Reference Standard, Ketorolac trometamol for peak identification, European Pharmacopoeia (EP) Reference Standard, Ketorolac Tromethamine, Pharmaceutical Secondary Standard; Certified Reference Material, 5-(phenylcarbonyl)-2,3-dihydropyrrolizinecarboxylic acid, 2-amino-2-(hydroxyme thyl)propane-1,3-diol, MolPort-005-934-838, HMS3649A22, AKOS015961616, AC-23357, A838010, [2-(hydroxymethyl)-1,3-bis(oxidanyl)propan-2-yl]azanium; 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylate, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate; [1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]ammonium

ID: 290

InChIKey: BWQAGVANIBSWBW-UHFFFAOYSA-M
SMILES: C[N+]1=CC2=C(C3=C(C=C2CC1)OCO3)OC.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 160908
synonyms found at PubChem are:
Cotarnine chloride, 10018-19-6, UNII-03F6B8N3QN, 03F6B8N3QN, 20276-45-3, Kotarninchlorid, 7,8-dihydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolinium chloride, 4-methoxy-6-methyl-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride, Cotarninium chloride, Cotarninium chloratum, Cotarnine chloride [NF], 7,8-Dihydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolinium chloride, EINECS 233-012-1, NSC 24824, AC1L4OG7, AC1Q1SO0, SPECTRUM100595, CHEMBL2104111, OR7175T, MolPort-000-835-851, NSC24824, ZX-AT022254, NSC-24824, 4-methoxy-6-methyl-7,8-dihydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride, AKOS024458727, CCG-214320, MCULE-3248666309, ACM20276453, NCGC00095441-01, FT-0603180, FT-0624072, SR-01000758972, J-000062, SR-01000758972-2, 1,5-g]isoquinolinium, 7,8-dihydro-4-methoxy-6-methyl-, chloride, 1,3-Dioxolo(4,5-g)isoquinolinium, 7,8-dihydro-4-methoxy-6-methyl-, chloride (8CI)(9CI), 4-methoxy-6-methyl-2H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride

ID: 291

InChIKey: BWUMVFCXSYXUOV-AFIPUWLUSA-N
SMILES: C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@]7(C[C@H]([C@H](C(O7)CO)O)O[C@H]8C([C@@H]([C@@H](C(O8)CO)O)O)O)O[C@@H]9C([C@H]([C@H](C(O9)C)O)O)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6713954
synonyms found at PubChem are:
Solanine alpha, SPBio_002859, Prestwick_524, Prestwick0_000640, Prestwick1_000640, Prestwick2_000640, HMS1569P22

ID: 292

InChIKey: BXDAOUXDMHXPDI-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66064
synonyms found at PubChem are:
Trifluoperazine dihydrochloride, 440-17-5, Trifluoperazine hydrochloride, Terfluzine, Stelazine, Triphthazine, Eskazinyl, Jatroneural, Tryptazine, Trazine, Trifluoperazine 2HCl, Trifluoperazine HCl, Fluoperazine, Eskazine, Triftazin, Trifluoroperazine hydrochloride, Tryptazine dihydrochloride, Triphthazine dihydrochloride, Calmazine, Stalazine hydrochloride, Stelazine dihydrochloride, UNII-6P1Y2SNF5V, Modalina, Trifluoroperazine dihydrochloride, Trifluoperazine (dihydrochloride), SKF 5019, Trifluoperazine hydrochloride (VAN), Trifluperazine dihydrochloride, 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride, EINECS 207-123-0, Fluoperazine dihydrochloride, 6P1Y2SNF5V, 10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride, AI3-50137, Trifluoperazine hydrochoride, Stelazine (TN), 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine dihydrochloride, 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride, 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-, dihydrochloride, 10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride, DSSTox_CID_25085, DSSTox_RID_80660, DSSTox_GSID_45085, 2-Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine dihydrochloride, CHEBI:9710, Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-, dihydrochloride, 10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2), SR-01000003020, NCGC00186653-01, CAS-440-17-5, 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;dihydrochloride, 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-, hydrochloride (1:2), 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2), Trifluoperazine hydrochloride [JAN], Prestwick_482, Trifluoperazine diHCl, Trifluoperazine maleate, Trifluoperazine hydrochloride [USP:JAN], AC1L24JK, TrifluoperazineDihydrochloride, C21H26Cl2F3N3S, SCHEMBL341516, SPECTRUM1500591, Trifluroperazine dihydrochloride, CHEMBL1257040, DTXSID1045085, CTK4I7934, HY-B0532A, BXDAOUXDMHXPDI-UHFFFAOYSA-N, MolPort-000-917-737, HMS1568P08, HMS1921G15, KS-000012JG, SKF-5019, Tox21_110017, Tox21_501232, CCG-40290, MFCD00012656, s3201, AKOS015895085, Tox21_110017_1, AC-8081, AN-8371, CS-2756, KS-5109, LP01232, NE57070, NCGC00013226-01, NCGC00094474-01, NCGC00094474-02, NCGC00094474-03, NCGC00261917-01, Trifluoperazine hydrochloride (JAN/USP), LS-105596, EU-0101232, FT-0600798, D00799, T 8516, Trifluoperazine dihydrochloride, >=99%, powder, I06-0498, SR-01000003020-2, W-106212, SR-01000003020-10, Trifluoperazine hydrochloride, meets USP testing specifications, Trifluoperazine Hydrochloride 1.0 mg/ml in Methanol (as free base), 2-Trifluoromethyl-10-[3-(1-methyl-4-piperazinyl)propyl]phenothiazine dihydrochloride, Trifluoperazine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Trifluoperazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Trifluoperazine dihydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, 10-[3-(4-methylpiperazinyl)propyl]-2-(trifluoromethyl)phenothiazine, chloride, chloride, MolPort-000-712-016, SBB057670, AKOS024370856, MCULE-1362676470, ST51006785, AKOS026750064

ID: 293

InChIKey: BXJAMTIXSSLKAH-UHFFFAOYSA-N
SMILES: CC(=O)OC1=C(C=CC(=C1)CC2COC3=C(C2=O)C=CC(=C3)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708755
synonyms found at PubChem are:
DEOXYSAPPANONE B 7,3'-DIMETHYL ETHER ACETATE, KBio2_003815, Spectrum_000767, SpecPlus_000729, AC1O8FMZ, Spectrum2_000179, Spectrum3_000214, Spectrum4_001619, Spectrum5_000377, BSPBio_001827, KBioGR_001997, KBioSS_001247, SPECTRUM201342, DivK1c_006825, SPBio_000077, CHEMBL1435118, SCHEMBL12998502, KBio1_001769, KBio2_001247, KBio2_006383, KBio3_001327, CCG-38387, SDCCGMLS-0066381.P001, NCGC00095506-01, NCGC00095506-02, SR-05000002614, SR-05000002614-1, BRD-A20368188-001-02-4, BRD-A20368188-001-03-2, [2-methoxy-5-[(7-methoxy-4-oxo-2,3-dihydrochromen-3-yl)methyl]phenyl] acetate

ID: 294

InChIKey: BXKDSDJJOVIHMX-UHFFFAOYSA-N
SMILES: CC[N+](C)(C)C1=CC(=CC=C1)O.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 8307
synonyms found at PubChem are:
Edrophonium chloride, 116-38-1, N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride, Antirex, Tensilon chloride, Edrophonii chloridum, Ethyl(m-hydroxyphenyl)dimethylammonium chloride, Cloruro de edrofonio, Chlorure d'edrophonium, Edrophonium (chloride), Edrofonio cloruro [DCIT], UNII-QO611KSM5P, N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride, TENSILON PRESERVATIVE FREE, Edrophonii chloridum [INN-Latin], Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride, Cloruro de edrofonio [INN-Spanish], EINECS 204-138-4, Chlorure d'edrophonium [INN-French], Edrophonium Chloride Preservative Free, QO611KSM5P, MLS000028677, CHEBI:4759, C10H16NO.Cl, Ammonium, dimethylethyl(m-hydroxyphenyl)-, chloride, SMR000058672, Tensilon (TN), DSSTox_CID_2978, (3-hydroxyphenyl)dimethylethylammonium chloride, Enlon (TN), DSSTox_RID_76815, 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride, DSSTox_GSID_22978, Ethyl-[m-Hydroxy phenyl]-dimethyl ammonium chloride, AMMONIUM, ETHYL(m-HYDROXYPHENYL)DIMETHYL-, CHLORIDE, Edrofonio cloruro, SR-01000000275, NCGC00015409-02, CAS-116-38-1, Prestwick_192, Edrophonium chloride [INN:BAN:JAN], Edrophonium chloride [USP:INN:BAN:JAN], AC1L1QPQ, Opera_ID_1421, CHEMBL1128, SCHEMBL34789, MLS001074086, SPECTRUM2300219, C10H16NO, 312-48-1 (Parent), DTXSID1022978, CTK8C0141, HMS502I11, MolPort-003-665-564, HMS1568A08, HMS1922J20, HMS2093N16, HMS2095A08, HMS2233G08, HMS3259E12, HMS3261H03, HMS3369M15, HMS3712A08, Pharmakon1600-02300219, HY-B0882, KS-00000G4K, Tox21_110138, Tox21_500511, ANW-64241, CCG-39644, IN1917, NSC759577, 3-(ethyldimethylamino)phenol, chloride, AKOS015890417, Tox21_110138_1, CS-4337, DS-0552, Edrophonium chloride (JP17/USP/INN), LP00511, MCULE-3821322707, MP-0697, NC00561, NSC-759577, NCGC00015409-11, NCGC00093908-01, NCGC00093908-02, NCGC00093908-03, NCGC00093908-04, NCGC00093908-05, NCGC00261196-01, AK-95497, AN-43217, CPD000058672, LS-17989, SAM002564207, AB0038454, AX8127147, KB-295359, ST2413585, TC-152986, 4CH-007239, EU-0100511, FT-0657849, ST51014996, Y5827, dimethylethyl(m-hydroxyphenyl)-ammoniuchloride, ethyl(m-hydroxyphenyl)dimethyl-ammoniuchloride, D00994, E 3256, ethyl(3-hydroxyphenyl)dimethylammonium chloride, ethyl[m-hydroxyphenyl]-dimethylammonium chloride, ethyl-(3-hydroxyphenyl)-dimethylammonium chloride, ethyl-(3-hydroxyphenyl)-dimethylazanium chloride, A803607, ethyl-(3-hydroxyphenyl)-dimethyl-ammonium chloride, ethyl-(3-hydroxyphenyl)-dimethyl-azanium chloride, I01-6721, J-003433, n-ethyl-3-hydroxy-n,n-dimethyl-benzenaminiuchloride, SR-01000000275-2, SR-01000000275-4, SR-01000000275-6, Benzenaminium,N-ethyl-3-hydroxy-N,N-dimethyl-,chloride, Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (1:1), Edrophonium chloride, EuropePharmacopoeia (EP) Reference Standard, Edrophonium chloride, United States Pharmacopeia (USP) Reference Standard

ID: 295

InChIKey: BXLAVJWSFYZDPF-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 97143
synonyms found at PubChem are:
3',4'-dimethoxyflavonol, 6889-80-1, 3-HYDROXY-3',4'-DIMETHOXYFLAVONE, UNII-9B35R9JIHA, NSC 102051, 2-(3,4-dimethoxyphenyl)-3-hydroxychromen-4-one, NSC102051, 9B35R9JIHA, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-hydroxy-, 2-(3,4-Dimethoxyphenyl)-3-hydroxy-4H-chromen-4-one, NSC-102051, Spectrum2_001702, Spectrum3_001681, AC1L3XX3, BSPBio_003202, CHEMBL77098, SPECTRUM1505278, SPBio_001684, AC1Q6E17, SCHEMBL4285872, CTK2F5718, KBio3_002422, ZINC39299, DTXSID20218968, BXLAVJWSFYZDPF-UHFFFAOYSA-N, MolPort-000-695-720, CCG-38784, STK183045, AKOS002317497, MCULE-1160192481, SDCCGMLS-0066918.P001, NCGC00095705-01, NCGC00095705-02, AC-28397, NCI60_000057, ST055992, FT-0707161, 2-(3,4-dimethoxyphenyl)-3-hydroxy-chromen-4-one, SR-05000002552, SR-05000002552-1, 3-hydroxy-2-(3,4-dimethoxyphenyl)-4h-chromen-4-one, BRD-K92171060-001-03-4, I14-21783, 2-(3,4-Dimethoxyphenyl)-3-hydroxy-4H-1-benzopyran-4-one

ID: 296

InChIKey: BXNANOICGRISHX-UHFFFAOYSA-N
SMILES: CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=C(C(=O)O2)Cl)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2871
synonyms found at PubChem are:
COUMAPHOS, Asuntol, 56-72-4, Coumafos, Asunthol, Baymix, Resitox, Azunthol, Muscatox, Agridip, Meldane, Meldone, Suntol, Baymix 50, CO-Ral, 3-Chloro-4-methyl-7-hydroxycoumarin diethyl thiophosphoric acid ester, Negashunt, Umbethion, Diolice, Bayer 21/199, coumophos, Cumafos, Cumafosum, Negasunt, NCI-C08662, 3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate, Cumafos [Dutch], BAY 21/199, Coumaphos [ISO], ENT 17,957, Caswell No. 335, Resistox, Phosphorothioic acid, O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester, Coumaphoscumafos, Cumafos [INN-Spanish], Coumafosum [INN-Latin], OMS 485, Bayer 21199, O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate, UNII-L08SZ5Z5JC, C14H16ClO5PS, 3-Chloro-7-hydroxy-4-methyl-coumarin O,O-diethyl phosphorothioate, CCRIS 180, O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl)phosphorothioate, HSDB 249, Diethyl 3-chloro-4-methylumbelliferyl thionophosphate, 3-Chloro-7-diethoxyphosphinothioyloxy-4-methylcoumarin, NSC 8944, EINECS 200-285-3, O,O-Diethyl O-(3-chloro-4-methylcoumarinyl-7) thiophosphate, O,O-Diethyl O-(3-chloro-4-methylumbelliferyl)phosphorothioate, O,O-Diethyl O-(3-chloro-4-methyl-7-coumarinyl)phosphorothioate, O-3-Chloro-4-methyl-7-coumarinyl O,O-diethyl phosphorothioate, EPA Pesticide Chemical Code 036501, BRN 0327083, L08SZ5Z5JC, 3-Chloro-4-methylumbelliferone O-ester with O,O-diethyl phosphorothioate, Diethyl thiophosphoric acid ester of 3-chloro-4-methyl-7-hydroxycoumarin, O-(3-Chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl thiophosphate, 3-Chloro-7-hydroxy-4-methyl-coumarin O-ester with O,O-diethyl phosphorothioate, Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester with O,O-diethyl phosphorothioate, O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-benzopyran-7-yl)phosphorothioate, AI3-17957, CHEBI:3903, NSC8944, O,O-Diaethyl-O-(3-chlor-4-methyl-cumarin-7-yl)-monothiophosphat, Coumafos (INN), Coumafos [INN], Thiophosphate de O,O-diethyle et de O-(3-chloro-4-methyl-7-coumarinyle), o-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) o,o-diethyl phosphorothioate, Phosphorothioic acid, O,O-diethyl ester, O-ester with 3-chloro-7-hydroxy-4-methylcoumarin, NCGC00094516-01, Diethyl-O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate, O,O-Diethyl O-(3-chloro-4-methylumbelliferone) thiophosphate, O,O-Dietil-O-(3-cloro-4-metil-cumarin-7-il-monotiofosfato), O,O-Diethyl-O-(3-chloor-4-methyl-cumarin-7-yl)monothiofosfaat, O-(3-Chloro-4-methyl-7-coumarinyl) O,O-diethylphosphorothioate, DSSTox_CID_347, O,O-Diethyl-O-(3-chloor-4-methyl-cumarin-7-yl)monothiofosfaat [Dutch], O,O-Dietil-O-(3-cloro-4-metil-cumarin-7-il-monotiofosfato) [Italian], O,O-Diaethyl-O-(3-chlor-4-methyl-cumarin-7-yl)-monothiophosphat [German], O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2h-benzopyran-7-yl) phosphorothioate, DSSTox_RID_75528, Phosphorothioic Acid O-(3-Chloro-4-Methyl-2-Oxo-2H-1-Benzopyran-7-yl) O,O-Diethyl Ester, Thiophosphate de O,O-diethyle et de O-(3-chloro-4-methyl-7-coumarinyle) [French], DSSTox_GSID_20347, Coumafosum, 3-chloro-7-diethoxyphosphinothioyloxy-4-methyl-chromen-2-one, 3-chloro-7-diethoxyphosphinothioyloxy-4-methylchromen-2-one, O,O-Dietil-O-(3-chloro-4-metil-cumarin-7-il-monotiofosfato), O,O-Diethyl-O-(3-chloro-4-methyl-cumarin-7-yl)monothiofosfaat, O-(3-chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl phosphorothioate, CAS-56-72-4, Coumaphos [ISO:BAN], Asantol, Muscotox, Perizin, Bazmix, Koral, Meldane (TN), Co-ral (phosphate), Spectrum_001767, SpecPlus_000350, AC1L1ENQ, Spectrum2_001845, Spectrum3_000805, Spectrum4_000645, Spectrum5_001924, BSPBio_002269, KBioGR_000989, KBioSS_002248, SPECTRUM330012, 4-18-00-00344 (Beilstein Handbook Reference), MLS002695922, DivK1c_006446, SCHEMBL120173, SPBio_001630, CHEMBL251680, DTXSID2020347, BAYER-21199, KBio1_001390, KBio2_002247, KBio2_004815, KBio2_007383, KBio3_001769, BXNANOICGRISHX-UHFFFAOYSA-N, MolPort-003-665-431, HMS3089A24, HMS3264G07, Pharmakon1600-00330012, ZINC608284, NSC-8944, O,O-diethyl O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate, Tox21_111290, Tox21_201841, Tox21_300769, BDBM50366033, CCG-39383, Coumaphos 10 microg/mL in Isooctane, LS-224, MFCD00041820, NSC759838, AKOS015903492, Tox21_111290_1, MCULE-8986409592, NSC-759838, Coumaphos 10 microg/mL in Acetonitrile, Coumaphos 100 microg/mL in Acetonitrile, NCGC00094516-02, NCGC00094516-03, NCGC00094516-04, NCGC00094516-05, NCGC00094516-06, NCGC00094516-08, NCGC00178730-01, NCGC00254673-01, NCGC00259390-01, AC-12672, AN-41695, AS-16079, CC-25986, S256, SMR000777904, ZB014609, WLN: T66 BOVJ DG E1 IOPS&O2&O2, FT-0603179, Coumaphos, PESTANAL(R), analytical standard, C11025, D07750, M-1115, AB00053007_02, O,O-diethyl O-(3-chloro-4-methylumbelliferone), 056C724, C-20952, SR-01000892650, Coumarin, O-ester with O,O-diethyl phosphorothioate, SR-01000892650-2, BRD-K41567533-001-02-6, I14-19193, 3-Chloro-4-methylumbelliferone o-ester with O,O-diethyl, 3-Chloro-7-diethoxyphosphinothioyloxy-4-methyl-2-chromenone, O-(3-Chloro-4-methylcoumarin-7-yl) O,O-diethyl phosphorothioate, Umbelliferone, 3-chloro-4- methyl-, O,O-diethyl phosphorothioate, Umbelliferone, 3-chloro-4-methyl-, O,O-diethyl phosphorothioate, 3-chloro-4-methylumbelliferone , O-ester with O,O-diethyl phosphorothioate, 3-chloro-4-methylumbelliferone, O-ester with O,O-diethyl phosphorothioate, Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) phosphorothioate, O-(3-Chloro-4-methyl-2-oxo-2H-chromen-7-yl) O,O-diethyl thiophosphate #, O-3-chloro-4-methyl-2-oxo-2H-chromen-7-yl O,O-diethyl phosphorothioate, 0,0-Diethyl 0-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) phosphorothioate, 3-chloro-7-hydroxy-4-methylcoumarin O-ester with O,O-diethyl phosphorothioate, Coumafos, Meldane, Asunthol, Azunthol, Muscatox, Agridip, Asuntol, Meldone, Resitox, Baymix, Coumarin, 3-chloro-7-hydroxy-4-methyl-, O- ester with O,O-diethylpyrophosphorothioate, Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester with O,O-diethylpyrophosphorothioate, O,O-diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) phosphorothioate, O-(3-chloro-4-methyl-2-oxo-2H-1-benzo pyran-7-yl) O,O-diethyl phosphorothioate, Phosphorothioic acid,O-diethyl ester, O-ester with 3-chloro-7-hydroxy-4-methylcoumarin

ID: 297

InChIKey: BYBLEWFAAKGYCD-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4189
synonyms found at PubChem are:
miconazole, 22916-47-8, Monistat, Monistat IV, Daktarin IV, Miconazolo, Miconazolum, Miconazol, Minostate, Dactarin, Monistat-Derm, MJR 1762, Miconazolum [INN-Latin], Vusion, Miconazolo [DCIT], Micozole, Zimycan, Florid(nitrate), Femizol-M, Miconazole 3, Miconazole-7, 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole, Miconasil Nitrate, Monazole 7, Miconazol [INN-Spanish], Brentan, R 18134, 1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole, NSC 170986, Aflorix(nitrate), Albistat(nitrate), Andergin(nitrate), Conofite(nitrate), Monista (nitrate), Monistat 1 Combination Pack, Monistat 5 Tampon, Micantin (nitrate), Monistat (TN), C18H14Cl4N2O, Daktarin, Miconazole 7 Combination Pack, Novo-Miconazole Vaginal Ovules, CCRIS 7924, Gyno-Daktar(nitrate), Lotrimin AF(nitrate), Monistat 3 Dual-Pak, Monistat 7 Dual-Pak, Epi-Monistat(nitrate), Miconazole (Monistat), Monistat 7 Vaginal Suppositories, Miconazole 7, Monistat 3, Monistat 5, Monistat 7, Miconazole [USAN:BAN:INN:JAN], CHEMBL91, EINECS 245-324-5, Monistat 3 Vaginal Ovules, 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole, BRN 0965511, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole, Miconazole nitrate salt, 1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-, Miconazole 3 Combination Pack, MCZ, CHEBI:82892, BYBLEWFAAKGYCD-UHFFFAOYSA-N, M-zole 3 Combination Pack, Monistat 3 Combination Pack, R-14,889, 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, NCGC00016770-01, Monistat Dual-pak, Micatin (TN), 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole, Imidazole, 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)-, (+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole, Monistat Dual- PAK, 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole, Oravig, 1-[2,4-Dichloro-beta-([2,4-dichloro-benzyl]oxy)phenethyl]imidazole, 1-[2,4-Dichloro-beta-([2,4-dichlorobenzyl]oxy)-phenethyl] imidazole, 1-(2,4-dichlorophenyl)-1-[(2,4-dichlorophenyl)methoxy]-2-imidazolylethane, 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole, imidazole, 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy) phenethyl)-, (+/-)-Miconazole nitrate salt, 1H-imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)-, 1H-Imidazole, 1-2-((2,4-dichlorophenyl)-2-((2,4-dichlorophenyl))methoxy)ethyl)-, (+-)-, imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI), Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-, Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI), 75319-47-0, NSC169434, Zimybase, Miconazole Base, 1-(2,4-Dichloro-beta-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole, R-14889, SR-01000000271, 1-(2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole, 1-[2-[(2,4-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Miconazole [USP:INN:BAN:JAN], Miconazex (TN), Daktarin (TN), Prestwick_335, Femizol (TN), Monistat iv (TN), Monistat-Derm (TN), Spectrum_000965, Prestwick0_000067, Prestwick1_000067, Prestwick2_000067, Prestwick3_000067, Spectrum2_001048, Spectrum3_000507, Spectrum4_000061, Spectrum5_001297, DSSTox_CID_3319, bmse000924, D00AXJ, AC1L1HM1, cid_4189, SCHEMBL2866, DSSTox_RID_76975, DSSTox_GSID_23319, Oprea1_091955, BSPBio_000253, BSPBio_002033, KBioGR_000581, KBioSS_001445, MLS002222203, DivK1c_000156, SPBio_000976, SPBio_002174, BPBio1_000279, Desenex, Monistat, Zeasorb-AF, GTPL2449, Miconazole (JP15/USP/INN), Miconazole (JP17/USP/INN), DTXSID6023319, SCHEMBL13934598, BDBM31772, CTK8B3340, KBio1_000156, KBio2_001445, KBio2_004013, KBio2_006581, KBio3_001533, MolPort-002-557-553, NINDS_000156, HMS1568M15, HMS2090B21, HMS2095M15, HMS2232B14, HMS3374J10, HMS3656E14, HMS3712M15, HY-B0454, KS-00000M1G, Tox21_110601, ANW-42336, DL-448, GA8311, MFCD00216019, NSC170986, s2536, SBB057453, STK834405, AKOS001574474, API0003382, CCG-220067, CS-2565, DB01110, DS-1881, MCULE-2106181573, NSC-170986, IDI1_000156, NCGC00018294-02, NCGC00018294-04, NCGC00018294-06, 22832-87-7 (NITRATE), AK-34234, CC-03621, LS-78378, NCI60_001353, NCI60_001380, SC-19243, SMR001307249, ST024747, SBI-0051448.P003, AB0023582, AB2000633, AX8055353, CAS-22916-47-8, DB-046018, KB-216913, ST2413510, TC-131081, 4CH-014451, AB00053500, FT-0628942, W4662, D00416, J10390, M-4631, AB00053500-23, AB00053500-24, AB00053500-25, AB00053500_26, AB00053500_27, AB00053500_28, 216M019, AE-641/01941016, C-28730, J-014898, SR-01000000271-5, BRD-A82396632-001-03-0, BRD-A82396632-008-02-7, Daktarin IV; MJR 1762; Monistat IV; NSC 17098, I14-14342, 1-[2,4dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]imidazole, 1-[2,4-Dichloro-beta-([2,4-dichlorobenzyl]oxy)-phenethyl]imidazole, 1-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy)-phenethyl]imidazole, 1-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]-imidazole, 1-[2,4-dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]imidazole, Imidazole,4-dichloro-.beta.-[(2,4-dichlorobenzyl)oxy]phenethyl]-, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-imidazol, 1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole, 1-[2,4-Dichloro-.beta.-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole, 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole, 1H-Imidazole,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, Imidazole, 1-(2,4-dichloro-.beta.-((2,4-dichlorobenzyl)oxy)phenethyl)-, 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole, 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid, 1-[2-[(2,4-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole #, Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)-(9CI), Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-(9CI)

ID: 298

InChIKey: BYGXICRJQZKUPA-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(CCNCC(=O)N)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6603827
synonyms found at PubChem are:
N-(3,3-Diphenylpropyl)glycinamide, 76991-05-4, 2-[(3,3-Diphenylpropyl)amino]acetamide, N20C, Acetamide, 2-[(3,3-diphenylpropyl)amino]-, 2-((3,3-Diphenylpropyl)amino)acetamide, NCGC00015378-01, Lopac-D-8816, AC1O7G2M, Lopac0_000489, MLS002153222, SCHEMBL1321258, CHEMBL1255662, CHEBI:92727, MolPort-003-941-179, HMS2233E15, HMS3261B19, HMS3373I06, ZINC1552924, Tox21_500489, 2-(3,3-diphenylpropylamino)acetamide, AKOS028108784, CCG-204580, LP00489, NCGC00015378-03, NCGC00015378-04, NCGC00015378-05, NCGC00092339-02, NCGC00092339-03, NCGC00261174-01, AS-44320, SMR001230694, EU-0100489, KS-00000283, D 8816, SR-01000075891, SR-01000075891-1, 2-amino-N-(3,3-diphenylpropyl)acetamide hydrochloride, BRD-K41143549-003-01-6, N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid

ID: 299

InChIKey: BYPFEZZEUUWMEJ-UHFFFAOYSA-N
SMILES: CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4740
synonyms found at PubChem are:
pentoxifylline, Trental, Oxpentifylline, 6493-05-6, Pentoxifyllin, Torental, Pentoxyphylline, Pentoxil, Dimethyloxohexylxanthine, Pentoxiphyllium, Vazofirin, Pentoxiphylline, Pentoxyfylline, Azupentat, Rentylin, Pentoxifilina, Pentoxifyllinum, Pentoxyphyllin, Agapurin, Durapental, 1-(5-Oxohexyl)theobromine, 3,7-Dimethyl-1-(5-oxohexyl)xanthine, BL 191, BL-191, 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione, Pentoxiphyllin, Pentoxyfilline, Hemovas, Ralofect, Vasofirin, Ikomio, 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-, Agapurin Retard, 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione, Pentoxifilina [INN-Spanish], Pentoxifyllinum [INN-Latin], Pentoxil (TN), Trental (TN), 1-(5-Oxohexyl)-3,7-dimethylxanthine, cis-9-Octadecenoyl coenzyme A, PENTOXYPHYLINE, 3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione, Theobromine, 1-(5-oxohexyl)-, EHT0201, SD6QCT3TSU, UNII-SD6QCT3TSU, IN1161, NSC637086, 3,7-Dimethyl-1-(5-oxohexyl)xantine, CHEMBL628, NSC 637086, 3,7-Dimethyl-1-(5-oxohexyl) xantine, 3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione, MLS000079026, CCRIS 6832, CHEBI:7986, Pentoxifylline (JAN/USP/INN), Pentoxifylline [USAN:INN:JAN], EHT-201, BYPFEZZEUUWMEJ-UHFFFAOYSA-N, C13H18N4O3, EHT 0201, EHT 0202, EHT-0201, EINECS 229-374-5, BRN 0558929, NCGC00015801-02, SMR000035998, 1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion, 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione, DSSTox_CID_3437, P 1784, DSSTox_RID_77028, DSSTox_GSID_23437, PNX, 3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione, 3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6(3H,7H)-dione, CAS-6493-05-6, SR-01000075641, Pentoxyifylline, Pentopak, 3arr, 3aru, 3tvx, BL191, Flexital (TN), Pentoxin (TN), Prestwick_608, Pentoxifylline,(S), Pentox (TN), Artal (TN), Spectrum_001444, 2a3c, AC1L1IUN, Opera_ID_1800, Prestwick0_000196, Prestwick1_000196, Prestwick2_000196, Prestwick3_000196, Spectrum2_001181, Spectrum3_001820, Spectrum4_000227, Spectrum5_001161, Lopac-P-1784, D09QEI, Lopac0_000936, SCHEMBL34039, BSPBio_000151, BSPBio_003439, KBioGR_000893, KBioSS_001924, MLS000758298, MLS001201764, MLS001424051, BIDD:GT0174, DivK1c_000729, SPECTRUM1503611, SPBio_001221, SPBio_002072, BPBio1_000167, GTPL7095, DTXSID7023437, BDBM10850, CTK8G2308, HMS502E11, KBio1_000729, KBio2_001924, KBio2_004492, KBio2_007060, KBio3_002942, MolPort-001-823-263, NINDS_000729, HMS1568H13, HMS1922E16, HMS2051N06, HMS2090H13, HMS2093G21, HMS2095H13, HMS2235C16, HMS3262L14, HMS3370D09, HMS3393N06, HMS3712H13, Pharmakon1600-01503611, BCP29306, HY-B0715, ZINC1530776, Tox21_110223, Tox21_500936, BBL016497, BG0286, CCG-36382, MFCD00063379, NSC758481, PDSP1_001015, PDSP2_000999, STK177321, AKOS000541484, Tox21_110223_1, AC-8381, AN-8052, API0003788, CS-2954, DB00806, LP00936, MCULE-9951939936, NC00255, NSC-637086, NSC-758481, VZ33607, 3,7-dimethyl-1-(5-oxohexyl)-xanthine, CAS-1677687, IDI1_000729, NCGC00015801-01, NCGC00015801-03, NCGC00015801-04, NCGC00015801-05, NCGC00015801-06, NCGC00015801-07, NCGC00015801-08, NCGC00015801-09, NCGC00015801-10, NCGC00015801-12, NCGC00015801-17, NCGC00067069-02, NCGC00067069-03, NCGC00067069-04, NCGC00067069-05, NCGC00178062-01, NCGC00178062-02, NCGC00261621-01, AS-13662, BAS 00897429, CPD000035998, Pentoxifylline [USAN:USP:INN:BAN:JAN], SAM001247011, SC-23298, SBI-0050910.P003, 1-(5-oxohexyl)theobromine (pentoxifylline), LS-149385, AB00052363, EU-0100936, FT-0603570, FT-0657886, H3041, P2050, ST50242554, V0152, C07424, D00501, J10071, AB00052363-17, AB00052363_18, AB00052363_21, 5-26-14-00081 (Beilstein Handbook Reference), 3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione, I06-1592, SR-01000075641-1, SR-01000075641-4, SR-01000075641-7, SR-01000075641-9, BRD-K57569181-001-05-1, BRD-K57569181-001-16-8, 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydropurine-2,6-dione, 3,7-dimethyl-1-(5-oxohexyl)-1,3,7-trihydropurine-2,6-dione, 3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione #, Px

ID: 300

InChIKey: BYUCSFWXCMTYOI-ZRDIBKRKSA-N
SMILES: C1C/C(=C\Br)/OC(=O)C1C2=CC=CC3=CC=CC=C32

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5940264
synonyms found at PubChem are:
bromoenol lactone, HELSS, 88070-98-8, 6-Btnpo, BTNP, bromoenolactone, C16H13BrO2, CHEMBL6206, BEL, 6-(Bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one, Haloenol lactone suicide substrate, BYUCSFWXCMTYOI-ZRDIBKRKSA-N, (E)-6-(Bromomethylene)-3-(1-naphthalenyl)tetrahydro-2H-pyran-2-one, (E)-6-(Bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-Pyran-2-one, (6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one, 2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (E)-, BEL cpd, SR-01000075707, E-6-(Bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one, AC1NZRTK, D09YUL, D0V3RE, Lopac0_000150, GTPL5149, SCHEMBL2060001, SCHEMBL2060074, MolPort-003-940-411, HMS3649C04, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one, Bromoenol lactone, >=98% (TLC), 1643AH, BDBM50046268, MFCD00270871, CCG-204245, LP00150, NCGC00015141-02, NCGC00015141-03, NCGC00015141-04, NCGC00093640-01, NCGC00093640-02, LS-178035, EU-0100150, SR-01000075707-1, SR-01000075707-5, (6E)-6-(bromomethylidene)-3-(naphthalen-1-yl)oxan-2-one, 6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyran-2-one, 6E-(Bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one, BEL; E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one, (E)-6-(bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one, 6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tetrahydro-pyran-2-one

ID: 301

InChIKey: BYVWXQRJRYELNP-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1C2C(=O)C(C3=C(C=C(C=C3O2)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 53708475
synonyms found at PubChem are:
(+/-) taxifolin, BDBM50049400, 3,5,7,3'',4''-pentahydroxyflavanone, 2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chroman-4-one, (2R,3R)-2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chroman-4-one

ID: 302

InChIKey: BYYQYXVAWXAYQC-IBGZPJMESA-N
SMILES: CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 132837
synonyms found at PubChem are:
L-732,138, 148451-96-1, 3,5-Bis(tfm)Bz nactrp, L-732138, 3,5-Bis(trifluoromethyl)benzyl N-acetyltryptophan, N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester, L 732138, CHEMBL22870, L732138, N-Acetyl-L-trp-3,5-bistrifluoromethylbenzyl ester, N-Acetyl-L-tryptophan-3,5-bistrifluoromethylbenzyl ester, N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester, [3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate, AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER, L-Tryptophan, N-acetyl-, (3,5-bis(trifluoromethyl)phenyl)methyl ester, Tocris-0868, Lopac-A-5330, D08ZBV, AC1L31NR, Lopac0_000028, MLS002172463, BIDD:GT0377, GTPL9461, SCHEMBL3682000, BDBM21016, DTXSID20163989, HMS2234A11, HMS3260E17, ZINC598586, Tox21_500028, MFCD00237267, AKOS015898307, API0007694, CCG-204124, LP00028, NCGC00015066-01, NCGC00024832-01, NCGC00024832-02, NCGC00024832-03, NCGC00024832-04, NCGC00260713-01, SMR001254094, ZB014526, LS-158105, B6478, EU-0100028, A 5330, SR-01000075194, SR-01000597431, I10-1459, SR-01000075194-1, SR-01000597431-1, N-acetyl-l-tryptophan 3,5-bis(trifluoromethyl) benzyl ester, N-Acetyl-L-trytophan 3,5-bis(trifluoromethyl)benzyl ester, (S)-3,5-bis(trifluoromethyl)benzyl 2-acetamido-3-(1H-indol-3-yl)propanoate, N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester, >=99% (TLC), powder

ID: 303

InChIKey: BZKPWHYZMXOIDC-UHFFFAOYSA-N
SMILES: CC(=O)NC1=NN=C(S1)S(=O)(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1986
synonyms found at PubChem are:
acetazolamide, 59-66-5, Diamox, Acetazolamid, Diacarb, Glaupax, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, Defiltran, Nephramide, Acetamox, Cidamex, Diluran, Edemox, Dehydratin, Diuramid, Diutazol, Duiramid, Eumicton, Natrionex, Nephramid, Phonurit, Diakarb, Donmox, Fonurit, Glupax, Vetamox, Didoc, SK-acetazolamide, Diuriwas, Acetazolamida, Acetazolamidum, Acetazoleamide, Acetozalamide, Diureticum-holzinger, Acetamidothiadiazolesulfonamide, 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, Acetazolamine, Acetazolam, Atenezol, Diuramide, Glaumox, Diamox Sequels, Apo-Acetazolamide, 4-Diamox, Ak-Zol, Carbonic Anhydrase Inhibitor No. 6063, 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide, Acetazolamidum [INN-Latin], Acetazolamida [INN-Spanish], Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-, Storzolamide, Dazamide, Carbonic anhydrase inhibitor 6063, UNII-O3FX965V0I, 2-Acetamido-5-sulfonamido-1,3,4-thiadiazole, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide, NSC 145177, 1,3,4-Thiadiazole-2-sulfonamide, 5-acetamido-, Diamox (TN), Acetazolamide [INN:BAN:JAN], C4H6N4O3S2, CCRIS 5811, Acetazolamide (AAZ), Acetazolamide Sodium, (Sterile), HSDB 3002, 5-Acetamide-1,3,4-thiadiazole-2-sulfonamide, CHEMBL20, Acetazolamide sodium, EINECS 200-440-5, N-(5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl)acetamide, AI3-52458, MLS000028435, O3FX965V0I, CHEBI:27690, BZKPWHYZMXOIDC-UHFFFAOYSA-N, Acetazolamide, Monosodium Salt, Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-, CAS-59-66-5, NCGC00015074-10, Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-, SMR000058394, DSSTox_CID_2544, 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide, A 6011, DSSTox_RID_76621, DSSTox_GSID_22544, N-(5-Sulfamoyl-[1,3,4]thiadiazol-2-yl)-acetamide, N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide, N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide, Acetadiazol, Glauconox, HumaZolamide, ApoAcetazolamide, Huma Zolamide, Huma-Zolamide, AkZol, Apo Acetazolamide, Acetazolamide Related Compound (5-acetamido-1,3,4-thiadiazole-2-sulfonic acid), Ak Zol, N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl]acetamide, SR-01000000065, DiamoxSequels, Prestwick_4, 1azm, 1yda, 1ydb, 1ydd, 1zsb, 2xtk, 3czv, 3ucj, Acetazolamide, 5, Acetazolamide [USP:INN:BAN:JAN], Acerazolamide, AAZ, Acetazolamide, AAZ, Acetazolamide, AZA, Acetazolamide, AZM, ACMC-20gwkd, PubChem12858, Spectrum_000018, 1jd0, 2h4n, 2uy4, 3dc3, 3hs4, 3ml5, 4g0c, Acetazolamide ICN Brand, Opera_ID_288, Acetazolamide Grin Brand, AZA2, Acetazolamide Jumer Brand, Acetazolamide Orion Brand, Prestwick0_000003, Prestwick1_000003, Prestwick2_000003, Prestwick3_000003, Spectrum2_000082, Spectrum3_000284, Spectrum4_000139, Spectrum5_000738, Lopac-A-6011, Acetazolamide Apotex Brand, Acetazolamide Chiesi Brand, Acetazolamide Dioptic Brand, Acetazolamide Llorens Brand, D0E1SW, ICN Brand of Acetazolamide, AC1L1CO5, Grin Brand of Acetazolamide, Acetazolamide Medphano Brand, Jumer Brand of Acetazolamide, Orion Brand of Acetazolamide, Acetazolamide Novopharm Brand, Lopac0_000039, Monosodium Salt Acetazolamide, SCHEMBL23219, BSPBio_000005, BSPBio_001788, KBioGR_000558, KBioSS_000358, Apotex Brand of Acetazolamide, Chiesi Brand of Acetazolamide, KSC270I0P, MLS001148438, Acetazolamide Wassermann Brand, BIDD:GT0643, DivK1c_000017, SPECTRUM1500102, Dioptic Brand of Acetazolamide, Llorens Brand of Acetazolamide, SPBio_000004, SPBio_001926, BPBio1_000007, GTPL6792, Medphano Brand of Acetazolamide, (non-d)Acetazolamide-13C2-d3, Acetazolamide, >=99%, powder, DTXSID7022544, Novopharm Brand of Acetazolamide, SCHEMBL11049053, BDBM10880, BZKPWHYZMXOIDC-UHFFFAOYSA-, CTK1H0407, HMS500A19, KBio1_000017, KBio2_000358, KBio2_002926, KBio2_005494, KBio3_001288, KS-00000UPN, Acetazolamide (JP15/USP/INN), Acetazolamide (JP17/USP/INN), N-[5-(Aminosulfonyl)-1,3,4-thiadiozol-2-yl]-Acetamide, Wassermann Brand of Acetazolamide, Acetazolamide, analytical standard, MolPort-001-783-578, NINDS_000017, HMS1568A07, HMS1920A05, HMS2091G05, HMS2095A07, HMS2232G23, HMS3259I13, HMS3260G19, HMS3370P01, HMS3712A07, Pharmakon1600-01500102, WLN: T5NN DSJ CSZW EMV1, Ciba Vision Brand of Acetazolamide, ALBB-023617, EBD55026, HY-B0782, ZINC3813042, Tox21_110078, Tox21_201559, Tox21_302773, Tox21_500039, CCG-38900, MFCD00003105, NSC145177, NSC755854, s4506, SBB056640, AKOS000715163, Tox21_110078_1, AN-5544, CS-3568, DB00819, LP00039, MCULE-4029778803, NC00491, NSC-145177, NSC-755854, IDI1_000017, Storz Brand of Acetazolamide Preparation, Wyeth Brand of Acetazolamide Preparation, 1424-27-7 (mono-hydrochloride salt), NCGC00015074-01, NCGC00015074-02, NCGC00015074-03, NCGC00015074-04, NCGC00015074-05, NCGC00015074-06, NCGC00015074-07, NCGC00015074-08, NCGC00015074-09, NCGC00015074-11, NCGC00015074-12, NCGC00015074-14, NCGC00015074-15, NCGC00023455-03, NCGC00023455-04, NCGC00023455-05, NCGC00023455-06, NCGC00023455-07, NCGC00256374-01, NCGC00259108-01, NCGC00260724-01, AC-12779, AS-13169, BAS 01585728, CJ-10773, CPD000058394, H501, LS-10227, SAM002554883, SC-20738, SBI-0050028.P004, 2-Acetamido-5-sulfonamido-1,4-thiadiazole, 5-Acetamide-1,4-thiadiazole-2-sulfonamide, 2-Acetamido-5-sulfamoyl-1,3,4-thiadiazole, 5-Acetamido-1,3,4-thiadiazol-2-sulfonamide, AB00051906, EU-0100039, FT-0621733, R1055, ST45022057, 1,4-Thiadiazole-2-sulfonamide, 5-acetamido-, C06805, D00218, J10059, 20506-EP2269989A1, 20506-EP2275420A1, 20506-EP2280008A2, 20506-EP2295406A1, 20506-EP2298772A1, 20506-EP2308562A2, 20506-EP2308839A1, 20506-EP2314585A1, AB00051906_15, 003A105, A832415, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)ethanamide, 2-ACETAMINO-1,3,4-THIADIAOLE-5-SULFONAMIDE, I09-0425, N-[5-Sulfamoyl-1,3,4-thiadiazol- 2-yl]acetamide, Q-200579, Q-200580, SR-01000000065-2, SR-01000000065-4, SR-01000000065-6, BRD-K43457670-001-22-9, BRD-K43457670-001-26-0, Z277559108, Acetazolamide, European Pharmacopoeia (EP) Reference Standard, Acetazolamide, United States Pharmacopeia (USP) Reference Standard, N - (5 - Sulfamoyl - 1,3, 4 - thiadiazol - 2 - yl) acetamide, Acetazolamide for system suitability, European Pharmacopoeia (EP) Reference Standard, 2-Acetamido-5-sulfamoyl-1,3,4-thiadiazole; 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, 5661-25-6, 8017-69-4, InChI=1/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)

ID: 304

InChIKey: BZQFBWGGLXLEPQ-REOHCLBHSA-N
SMILES: C([C@@H](C(=O)O)N)OP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 68841
synonyms found at PubChem are:
O-phospho-L-serine, Dexfosfoserine, phosphoserine, 407-41-0, L-O-Phosphoserine, Fosforina, O-Phosphoserine, L-SOP, L-Phosphoserine, 3-phosphoserine, PHOSPHONOSERINE, L-serine-O-phosphate, L-Serine O-phosphate, Dexfosfoserine [INN], Phosphatidalserine, 3-O-Phosphoserine, serine, O-phosphono-, (+)-L-Serine dihydrogen phosphate (ester), L-Seryl phosphate, UNII-VI4F0K069V, L-3-Phosphoserine, LSOP, O-phosphono-L-serine, L-O-Serine phosphate, L-Serinephosphoric acid, H-Ser(PO)-OH, L-2-amino-3-hydroxypropanoic acid 3-phosphate, EINECS 206-986-0, H-Ser(PO3H2)-OH, GNF-Pf-1028, CHEMBL284377, VI4F0K069V, (2S)-2-amino-3-(phosphonooxy)propanoic acid, CHEBI:15811, BZQFBWGGLXLEPQ-REOHCLBHSA-N, (2S)-2-amino-3-phosphonooxypropanoic acid, L-Serine phosphate, C3H8NO6P, DSSTox_CID_26348, DSSTox_RID_81552, (S)-2-amino-3-hydroxypropanoic acid 3-phosphate, DSSTox_GSID_46348, SEP, Phosphotidylserine, Phosphatidylserines, CAS-407-41-0, Phosphatidylserine [INCI], seriphos, Plasmenylserine, Phosphatidyl serine [WHO-DD], O3-phosphoserine, Phospho-L-serine, O-Phosphorylserine, L-Serinephosphorate, NCGC00163344-01, Serine O-phosphate, Serine dihydrogen phosphate (ester), Serine, O-phospho-, serine phosphate ester, O-Phosphoryl-L-serine, Tocris-0238, L-serine, O-phosphono-, AC1Q6RUY, bmse000399, D06PRT, D07PZQ, AC1L2AK1, SCHEMBL6846, Lopac0_000886, L-Serine, dihydrogen phosphate, Serine phosphate, L- (6CI), ARK086, GTPL1411, DTXSID1046348, BDBM17664, CTK0H5336, MolPort-003-939-112, HMS3262B14, HMS3264A13, Pharmakon1600-01506151, KS-000010EI, ZINC3869280, Tox21_112050, Tox21_500886, 7600AH, BN0400, FCH919862, MFCD00065935, NSC760136, O-Phospho-L-serine, ~95% (TLC), AKOS006239311, L-Serine dihydrogen phosphate (ester), Tox21_112050_1, CCG-204968, CS-7902, DB04522, LP00886, NSC-760136, NCGC00024512-01, NCGC00024512-02, NCGC00024512-03, NCGC00024512-04, NCGC00024512-05, NCGC00024512-06, NCGC00024512-07, NCGC00261571-01, 1446756-47-3, 7331-08-0, AN-44815, HY-15129, KB-59311, LS-184497, TC-165598, (2S)-2-amino-3-phosphonooxy-propanoic acid, (S)-2-Amino-3-(phosphonooxy)propanoic acid, EU-0100886, FT-0628015, FT-0695863, P0773, C01005, K-8676, L-Serine, dihydrogen phosphate (ester) (9CI), P 0878, AB01563211_01, Serine, dihydrogen phosphate (ester), L- (8CI), SR-01000597714, UNII-F1 component BZQFBWGGLXLEPQ-REOHCLBHSA-N, SR-01000597714-1, I14-56223, F1EE42DE-E913-4F09-A97B-F539EE869AB7, I14-108766, UNII-26C4VY6Z0M component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-2R86C98KDX component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-30KYC7MIAI component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-3L4WX7B1EI component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-3LH35AJA5L component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-470AD5VY1X component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-63CV1GEK3Y component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-6GV29P6OZA component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-7COY1HA6HK component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-7D44E6BN1B component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-84UK82T430 component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-8558G7RUTR component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-9J12WX5B6A component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-9J17BCS69U component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-9ZAR5FLK75 component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-FCR6T2IYVU component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-G05L7T7ZEQ component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-G0HAF1JK3T component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-GDV0MSK2SG component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-N8KUP1WS1O component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-O12PZI77AL component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-P409G2H90A component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-QM00M3504A component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-RQ6L463N3B component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-U2UT4677KR component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-W45O4X1TL9 component BZQFBWGGLXLEPQ-REOHCLBHSA-N, UNII-W98518XGZ3 component BZQFBWGGLXLEPQ-REOHCLBHSA-N, O-Phospho-L-serine, certified reference material, TraceCERT(R), UNII-29166358BF component BZQFBWGGLXLEPQ-REOHCLBHSA-N

ID: 305

InChIKey: BZZXQZOBAUXLHZ-UHFFFAOYSA-N
SMILES: CSC(=N)N.CSC(=N)N.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 13347
synonyms found at PubChem are:
867-44-7, S-Methylisothiourea hemisulfate, Carbamimidothioic acid, methyl ester, sulfate (2:1), 2-Methyl-2-thiopseudourea hemisulfate, NSC 516, S-Methylisothiourea sulfate (2:1), S-Methylthiouronium sulfate (2:1), Bis(2-methylisothiouronium) sulphate, EINECS 212-759-7, Methyl carbamimidothioate sulfate(2:1), Methylcarbamimidothioate sulfate (2:1), S-Methylisothiourea, Sulfate, 2-Methyl-2-thiopseudourea sulfate (2:1), AI3-50026, UNII-H834R05C26, Pseudourea, 2-methyl-2-thio-, sulfate (2:1), Bis(S-methylisothiouronium) sulfate, 2-Methyl-2-thiopseudourea, Sulfate, methyl carbamimidothioate hemisulfate, H834R05C26, S-Methyl-ITU, S-Methylisothiourea hemisulfate salt, Carbamimidothioic acid, methyl-, sulfate (2:1), SMT, W-104059, (S)-Methylisothiourea sulfate, 2986-19-8 (Parent), Carbamimidothioic acid,methyl ester (9CI), S-Methyl isothiourea sulfate, S-Methyl-iso-thiourea, AC1L21JR, KSC448G5D, CHEMBL1358112, DTXSID7061223, C4H14N4O4S3, CTK3E8351, MolPort-003-983-780, HMS3262G12, HMS3649K14, BCP26340, ZX-AT015724, Tox21_500755, BS0118, Methyl carbamimidothioate hemisulphate, SBB065776, AKOS003243960, AKOS016016032, CCG-204840, LP00755, OR17024, RP29789, NCGC00094095-01, NCGC00261440-01, AC-16449, AK-44125, AN-47810, CC-11326, SC-17976, S-Methylisothiourea hemisulfate salt, 98%, AB1004064, LS-126196, B6447, EU-0100755, FT-0082642, FT-0628897, M0442, ST24032501, Carbamimidothioic acid methyl ester hemisulfate, KS-00000064, Carbamimidothioicacid,methylester,sulfate(2:1), EN300-106747, M 3127, M-3984, bis(methylsulfanylmethanimidamide); sulfuric acid, 867M447, SR-01000946617, bis((methylsulfanyl)methanimidamide); sulfuric acid, I04-0276, SR-01000946617-1, F0001-2155, Z1741980405, 2-Methyl-2-thiopseudourea hemisulfate salt; S-Methyl-ITU; S-Methylthiuronium sulfate; SMT, 72046-63-0, NCGC00025367-01, Tocris-0776, S-Methylisothiuroniumsulfat, 2-Methylthiouronium sulfate, S-methylthiouronium sulphate, AC1O7H2U, S-methyl-thiouronium sulphate, SCHEMBL317855, SCHEMBL638465, S-methylisothiourea hemisulphate, S-methyl isothiourea hemisulfate, S-methyl-isothiourea hemisulphate, S-methylthiopseudourea hemisulfate, BZZXQZOBAUXLHZ-UHFFFAOYSA-N, MolPort-006-112-514, bis (S-methylisothiourea) sulphate, 2-methyl-isothiourea hemisulfate salt, AKOS024458643, [amino(methylsulfanyl)methylidene]azanium sulfate

ID: 306

InChIKey: CABYWQOCCVFNHX-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)OC2=CC=C(C=C2)CNC(=O)C3=NC(=C4C=C(C(=O)C(=C4)Br)Br)NO3

biological descriptors:

CFTR relevance: CFTR inhibitor/ potentiator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction binds to CFTR
subcellular compartment Apical membrane & subapical compartment

reference list:

"G Cui" "BB Stauffer" "N Khazanov" "DT Infield" "H Senderowitz" "NA McCarty" "BR Imhoff"

CID is 44241539
synonyms found at PubChem are:
iOWH-032, 1191252-49-9, IOWH032, 3-(3,5-Dibromo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide, UNII-8Y3GDT6YWV, 8Y3GDT6YWV, IOWH 032, C22H15Br2N3O4, SCHEMBL1114552, KS-00000SAW, EX-A327, DSFNLJXHXBIKDS-UHFFFAOYSA-N, MolPort-035-395-840, HMS3653C14, AOB87123, BCP08439, 2156AH, s7329, ZINC68151296, AKOS024259261, AKOS026750509, ZINC145673230, CD-1778, CS-1744, DB12959, NCGC00386303-01, 4CA-0651, AK151417, BC600405, HY-18337, SC-94667, AX8288033, KB-308544, FT-0732295, 3-(3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)-N-(4-phenoxybenzyl)-2,3-dihydro-1,2,4-oxadiazole-5-carboxamide, 3-[3,5-Dibromo-4-(4-methoxybenzyloxy)phenyl]-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide

ID: 307

InChIKey: CAHGCLMLTWQZNJ-BQNIITSRSA-N
SMILES: C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 246983
synonyms found at PubChem are:
lanosterol, 79-63-0, Lanosterin, Lanster, Botalan base 138, Lanosta-8,24-dienol, Lanosta-8,24-dien-3beta-ol, UNII-1J05Z83K3M, NSC60677, (3beta)-lanosta-8,24-dien-3-ol, Botalan base, CHEBI:16521, CAHGCLMLTWQZNJ-BQNIITSRSA-N, Lanosta-8,24-dien-3.beta.-ol, 1J05Z83K3M, MFCD00021108, Lanostadien-3-beta-ol, NSC 60677, Lanosta-8,24-dien-3-ol, (3beta)-, Lanosta-8,24-dien-3-ol, Lanosta-8,24-dien-3-ol, (3.beta.)-, Lanosta-8,24-dien-3-beta-ol, 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol, EINECS 201-214-9, Cholesta-8,24-dien-3-ol, 4,4,14-trimethyl-, (3.beta.,5.alpha.)-, (3-beta)-Lanosta-8,24-dien-3-ol, BRN 2226449, (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, AI3-23643, Lanostereol, Cholesta-8,24-dien-3-ol, 4,4,14-trimethyl-, (3beta,5alpha)-, (3.beta.)-Lanosta-8,24-dien-3-ol, Lanosta-8,24-dien-3-ol, (3-beta)-, lanosterol 50-60%, AC1L6JAE, D0P4PQ, 8,24-Lanostadien-3beta-ol, Lanosta-8, (3.beta.)-, 8,24-Lanostadien-3|A-ol, Lanosterol, >=93%, powder, SCHEMBL145834, CHEMBL225111, GTPL2746, DTXSID1040744, 3|A-Hydroxy-8,24-lanostadiene, 3beta-Hydroxy-8,24-lanostadiene, MolPort-000-146-138, ZINC3870056, LMST01010017, NSC-60677, (3 beta)-Lanosta-8,24-dien-3-ol, AKOS024307002, DB03696, Lanosta-8,24-dien-3beta-ol (8CI), MCULE-6692951185, NCGC00164398-01, (3beta,20R)-Lanosta-8,24-dien-3-ol, FT-0627682, 7073-EP2277507A1, 7073-EP2286795A1, 7073-EP2298776A1, C01724, (3alpha)-4,4,14-trimethyl-Cholesta-8,24-dien-3-ol, (3beta,5alpha)-4,4,14-trimethylcholesta-8,24-dien-3-ol, 4,4,14alpha-trimethyl-5alpha-cholesta-8,24-dien-3beta-ol, C4CA2F34-1C1A-4673-AC43-E547708CB228, Cholesta-8, 4,4,14-trimethyl-, (3.beta.,5.alpha.)-, UNII-U431865SO1 component CAHGCLMLTWQZNJ-BQNIITSRSA-N, (3beta,5alpha)-4,4,14-trimethyl-Cholesta-8,24-dien-3-ol, (3S,5R,10S,13R,14R,17R)-17-[(1R)-1,5-dimethylhex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

ID: 308

InChIKey: CAHGCLMLTWQZNJ-WZLOIPHISA-N
SMILES: C[C@H](CCC=C(C)C)[C@@H]1CC[C@]2([C@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441678
synonyms found at PubChem are:
Euphol, 514-47-6, Euphadienol, (+)-Euphol, Eupha-8,24-dienol, CHEBI:4940, Euphol (6CI), (20R)-(+)-triucalla-8,24-diene-3beta-ol, (3S,5R,10S,13S,14S,17S)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, alpha-Euphol, (s)-euphol, (+)-alpha-Euphol, AC1L9BGD, 13alpha,14beta,17betaH-Lanosta-8,24-dien-3beta-ol (8CI), SCHEMBL541497, CHEMBL465181, ZINC4097719, 7162AB, AKOS016010616, LMPR0106090002, AJ-48007, KB-277032, FT-0698509, ST24047202, C08624, (3beta,13alpha,14beta,17alpha)-Lanosta-8,24-dien-3-ol, Lanosta-8,24-dien-3-ol, (3.beta.,13.alpha.,14.beta.,17.alpha.)-, (3S,5R,10S,13S,14S,17S)-17-[(1R)-1,5-dimethylhex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol

ID: 309

InChIKey: CANOJKGQDCJDOX-VZUCSPMQSA-N
SMILES: C1=CC(=C(C=C1/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5328760
synonyms found at PubChem are:
Tyrphostin AG 538, AG 538, AG-538, NSC676485, (E)-2-(3,4-dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile, alpha-Cyano-(3,4-dihydroxy)cinnamoyl-(3′,4′-dihydroxyphenyl)ketone, Tyrphostin deriv. 24, Lopac-T-7822, D0NH7M, AC1NS5A3, Lopac0_001261, MLS002153408, CHEMBL56393, BDBM4293, SCHEMBL2678764, SCHEMBL2678765, REGID_for_CID_660907, CHEBI:92138, cid_5328760, REGID_for_CID_5328760, HMS2233K10, HMS3263N04, 133550-18-2, ZINC3871438, Tox21_501261, HSCI1_000189, CCG-205335, LP01261, NSC-676485, NCGC00016054-01, NCGC00016054-02, NCGC00016054-03, NCGC00016054-04, NCGC00016054-05, NCGC00094499-01, NCGC00094499-02, NCGC00261946-01, SMR001230786, EU-0101261, T 7822, SR-01000076178, J-006400, SR-01000076178-1, BRD-K07888196-001-01-8, 3-(3,4-Dihydroxyphenyl)-2-[1-(3,4-dihydroxyphenyl)methanoyl]acrylonitrile, (2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphenyl)carbonyl]prop-2-enenitrile, (alphaE)-alpha-[(3,4-Dihydroxyphenyl)methylene]-3,4-dihydroxy-beta-oxo-benzenepropanenitrile, 3,4-Dihydroxy-a-(3,4-dihydroxybenzoyl)-cis-cinnamonitrile 2-Cyano-3 ,4 -dihydroxyacetophenone

ID: 310

InChIKey: CANPFCFJURGKAX-JTQLQIEISA-N
SMILES: CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2O)I)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107995
synonyms found at PubChem are:
IBZM, Iodobenzamide, UNII-9J5D4ZN1JK, 9J5D4ZN1JK, S(-)-IBZM, CHEMBL267723, 123I-IBZM, (S)-(-)-IBZM, BRN 4322848, C15H21IN2O3, IOLOPRIDE, (S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide, (S)-N-(1-Ethyl-2-pyrrolidinyl)methyl-2-hydroxy-3-iodo-6-methoxybenzamide, 3-Iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide, n-{[(2s)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-3-iodo-6-methoxybenzamide, 84226-06-2, Benzamide, N-(((2S)-1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-3-iodo-6-methoxy-, Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-3-iodo-6-methoxy-, (S)-, N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide, AC1Q4PJQ, D06AIQ, Lopac0_000665, AC1L334Q, SCHEMBL3811169, N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide, 130383-75-4, BDBM50012961, ZINC22061339, AKOS027382090, CCG-204751, LS-26832, I-139, SR-01000075463, SR-01000075463-1, 3-iodo-N-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-6-methoxybenzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide, (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide, (S)-(-)-3-Iodo-2-hydroxy-6-methoxy-N[(1-ethyl-2-pyrrolidinyl)methyl]benzamide, (s)-N-[(1-ethyl-2-pyrrolidinyl)]methyl-2-hydroxy-3-iodo-6-methoxybenzamide, (S)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-iodo-6-methoxybenzamide, N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide, N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM), N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM), N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide

ID: 311

InChIKey: CBGDIJWINPWWJW-IYSWYEEDSA-N
SMILES: C[C@@H]1[C@H](OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54680783
synonyms found at PubChem are:
citrinin, Antimycin, 518-75-2, (-)-citrinin, Citriain, NSC 186, (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid, UNII-3S697X6SNZ, CCRIS 175, NSC186, HSDB 3473, EINECS 208-257-2, BRN 0088597, 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-, 3S697X6SNZ, CHEBI:48707, C13H14O5, (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid, (3R-trans)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid, 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid, 3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxobenzo(c)pyran-7-carboxylic acid, NSC-186, Citrinin, 98%, Spectrum_000451, AC1Q6AAA, Spectrum2_000734, Spectrum3_000240, Spectrum4_001804, Spectrum5_000507, (3r,4s)-7-(dihydroxymethylidene)-3,4,5-trimethyl-3h-isochromene-6,8(4h,7h)-dione, BSPBio_001919, KBioGR_002411, KBioSS_000931, SPECTRUM210186, 5-18-09-00061 (Beilstein Handbook Reference), DivK1c_000646, SCHEMBL157775, SPBio_000688, AC1L569G, CTK1G9542, HMS502A08, KBio1_000646, KBio2_000931, KBio2_003499, KBio2_006067, KBio3_001419, CQIUKKVOEOPUDV-IYSWYEEDSA-N, MolPort-003-665-574, NINDS_000646, HMS1923C05, 3H-2-Benzopyran-7-carboxylicacid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R,4S)-, CCG-39048, MFCD00006912, ZINC19795941, AKOS030254668, LS-7280, SDCCGMLS-0066537.P001, IDI1_000646, NCGC00160164-01, NCGC00160164-02, NCGC00160164-03, NCI60_001544, FT-0602942, ST50405294, C16765, SR-05000002496, WLN: T66 CO HV AUT&J D1 E1 G1 IVQ JQ, SR-05000002496-1, Citrinin, from Penicillium citrinum, >=98% (HPLC), Citrinin solution, 100 mug/mL in acetonitrile, analytical standard, (4S,3R)-8-hydroxy-3,4,5-trimethyl-6-oxoisochromane-7-carboxylic acid, (3R,4S)-3,4,5-Trimethyl-6-hydroxy-8-oxo-4,8-dihydro-3H-2-benzopyran-7-carboxylic acid, (3R,4S)-7-(dihydroxymethylidene)-3,4,5-trimethyl-3,4-dihydroisochromene-6,8-dione, (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-3,4-dihydroisochromene-7-carboxylic acid, 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, 8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid #, 3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-,(3R,4S)-, 3H-2-Benzopyran-7-carboxylic acid,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-, 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo, (3R-trans)-3H-2-benzopyran-7-carboxylic acid

ID: 312

InChIKey: CBGUOGMQLZIXBE-XGQKBEPLSA-N
SMILES: CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CCl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 32798
synonyms found at PubChem are:
CLOBETASOL PROPIONATE, 25122-46-7, Clobetasol 17-propionate, Clobex, Dermovate, Temovate, Embeline, Embeline E, Clobesol, Cormax, Olux, Temovate E, Olux-E, clobetasol 17-propanoate, GR 2/925, C25H32ClFO5, Clobestasol propionate, MLS000028708, Clobetasol propionate [USAN:JAN], CCI 4725, CGP 9555, 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate, EINECS 246-634-3, UNII-779619577M, [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate, CLOBETASOL PROPIONATE (EMOLLIENT), SMR000058745, CHEBI:31414, CCI-4725, DSSTox_CID_25907, DSSTox_RID_81219, DSSTox_GSID_45907, 21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione (11beta,16beta)-, 779619577M, Dermoxinale, Butavate, Dermoval, Yugofin, 21-chloro-9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate, 21-Chloro-9-fluoro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasolpropionate, Olux E, Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-methyl-, 17-propionate, Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11beta,16beta)-, Clobetasol propionate gel, Clarelux, Impoyz, NCGC00095078-01, CPD000058745, CAS-25122-46-7, Cormax (TN), Clobetasole propionate, Clobetasol propionate [USAN:USP:JAN], OLUX FOAM, Clobetasol propionate E, Propionic acid clobetasol, Opera_ID_1470, Clobetasolpropionat mikron., AC1L1OG9, AC1Q3T8C, SCHEMBL3997, cid_32798, MLS001076345, AMOT0927, GTPL7062, CHEMBL1159650, DTXSID6045907, BDBM39347, EBD6220, HMS2090A04, HMS2230H08, HMS3259A10, HMS3714M04, Clobetasol propionate (JP17/USP), BCP04125, ZINC3977767, Tox21_111414, MFCD00058499, s2584, AKOS015951278, Tox21_111414_1, BCP9000539, CCG-220781, CS-2594, DB01013, NC00551, NCGC00023373-03, NCGC00023373-04, AC-17990, AN-14318, AS-12555, CC-25914, Clobetasol propionate, analytical standard, HY-13600, BCP0726000094, AB1009262, LS-118433, D01272, AB00383081-10, AB00383081_11, 122C467, C-22667, SR-01000000280, SR-01000000280-4, BRD-K10799896-001-10-6, BRD-K10799896-001-26-2, Clobetasol propionate, European Pharmacopoeia (EP) Reference Standard, Clobetasol propionate, United States Pharmacopeia (USP) Reference Standard, 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasol for peak identification, European Pharmacopoeia (EP) Reference Standard, Clobetasol Propionate, Pharmaceutical Secondary Standard; Certified Reference Material, (11b,16b)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11 beta-hydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17-propionate, 21-Chloro-9alpha-fluoro-11beta,17alpha-dihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17-Propionate, CGP9555 pound>> CCl 4725 pound>>CGP 9555 pound>> CCl4725 pound>>CGP-9555 pound>> CCl-4725, Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-methyl-,17-propionate

ID: 313

InChIKey: CBOJBBMQJBVCMW-BTVCFUMJSA-N
SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)N)O)O)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 91431
synonyms found at PubChem are:
Glucosamine (hydrochloride), D-Glucosamine HCl, 2-Amino-2-deoxy-D-glucose hydrochloride, D-Glucosamine chloride, (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, D-Glucose, 2-amino-2-deoxy-, hydrochloride, Cosamin, Chitosamine hydrochloride, D-Glucosamine monohydrochloride, UNII-750W5330FY, NSC 758, EINECS 200-638-1, 2-Amino-D-glucose, 750W5330FY, NSC 234443, 2-Deoxy-2-amino-D-glucose hydrochloride, AI3-26077, 2-Amino-2-deoxy-beta-D-glucopyranose hydrochloride, Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-, D(+)-Glucosamine hydrochloride, Artrox (TN), AC1Q3EHY, 2-amino-2-deoxy-d-glucose hydrochloride(1:1), AC1L3M2A, SCHEMBL19711, D(+)-Glucosamin-hydrochlorid, KSC352Q4J, Glucosamine hydrochloride [NF], tetrahydroxyhexanal hydrochloride, CTK2F2844, D-( )-Glucosamine hydrochloride, D-Glucosamine Hydrochloride,(S), MolPort-009-756-412, Glucosamine hydrochloride {NF XXI], HY-N0733, ANW-35255, AKOS015951259, CS-4919, LS40322, RTR-022551, AS-14149, K096, KB-76462, LS-71672, SC-11339, AB1009254, TR-022551, ST24033997, ST50825652, A-8403, D08022, EC 200-638-1, (2R,3R,4S,5R)-2-amino-3,4,5,6-, Z1954805520, 7070F368-3591-43D6-830F-335576FD1BAE, 2-Amino-2-deoxy-D-glucose hydrochloride; Chitosamine hydrochloride, 1029131-60-9, 151799-45-0, 2002-25-7, 214046-22-7, 34673-29-5, 3615-52-9, 581076-92-8, 619328-18-6, 66573-21-5, 885318-70-7

ID: 314

InChIKey: CBPJQFCAFFNICX-LJQANCHMSA-N
SMILES: CC(C)C[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1549477
synonyms found at PubChem are:
Fmoc-D-Leu-OH, Fmoc-D-leucine, 114360-54-2, N-Fmoc-D-leucine, CHEMBL152028, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine, D-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid, N-9-FLUORENYLMETHYLOXYCARBONYL-D-LEUCINE, N- (9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE, (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid, (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid, (2R)-2-{[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO}-4-METHYLPENTANOIC ACID, (R)-2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-4-METHYLPENTANOIC ACID, Npc 15199, Fmoc-DLeu, (2R)-2-([(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO)-4-METHYLPENTANOIC ACID, PubChem10023, Spectrum_001482, Tocris-0675, FMOC-D-LEU, Spectrum2_001468, Spectrum3_001175, Spectrum4_000165, Spectrum5_001340, AC1LU88W, BSPBio_002789, KBioGR_000649, KBioSS_001962, KSC180A5F, DivK1c_001012, SCHEMBL800078, SPECTRUM1502083, SPBio_001395, 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid, N-ALPHA-FMOC-D-LEUCINE, AC1Q1O91, CTK0I0052, HMS503K05, KBio1_001012, KBio2_001962, KBio2_004530, KBio2_007098, KBio3_002289, CBPJQFCAFFNICX-LJQANCHMSA-N, MolPort-001-757-006, NINDS_001012, ACT05618, ANW-16688, BDBM50121968, CCG-39195, CF-187, MFCD00062957, ZINC82067502, AKOS015924103, AB02467, AC-8595, AM81874, AN-7851, CS-W008021, DS-2292, RTR-002668, (NPC-15199), IDI1_001012, n-(9-fluorenylmethoxycarbonyl)-d-leucine, NCGC00024724-01, NCGC00024724-02, NCGC00024724-03, AJ-27294, CPD000468730, Fmoc-D-Leu-OH, >=95.0% (TLC), KB-52049, SAM001246986, 9-FLUORENYLMETHOXYCARBONYL-D-LEUCINE, AB0004760, AB1002093, ST2413094, TR-002668, F0603, FT-0629919, N-(9H-Fluoren-9-ylmethoxycarbonyl)-D-leucine, B-6475, M03366, (R)-FMOC-2-AMINO-4-METHYLPENTANOIC ACID, N-(9-FLUORENYLMETHOXY)CARBONYL-D-LEUCINE, 360F542, A803174, SR-01000597659, J-300158, N-[(9H-Fluoren-9-Yl-Methoxy)Carbonyl]-D-Leucine, Q-101637, SR-01000597659-1, BRD-K65275554-001-02-1, BRD-K65275554-001-03-9, N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-LEUCINE, N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-LEUCINE, L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- [CAS], (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-methylpentanoic acid

ID: 315

InChIKey: CBQNSTKQBGIAEL-TWGQIWQCSA-N
SMILES: COC1=CC=CC=C1/C=N\O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 5368446
synonyms found at PubChem are:
2-Methoxybenzaldehyde oxime, AC1NSR3R, SCHEMBL2160888, MolPort-006-385-872, 54582-20-6, NSC27015, NSC-27015, STK398324, ZINC95627759, AKOS005434111, (alphaE)-N-Hydroxy-2-methoxybenzenemethaneimine, (Z)-N-hydroxy-1-(2-methoxyphenyl)methanimine, AB01326906-02, (NZ)-N-[(2-methoxyphenyl)methylidene]hydroxylamine

ID: 316

InChIKey: CBSOFSBFHDQRLV-UHFFFAOYSA-N
SMILES: CNCC1=CC=CC=C1.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 25979
synonyms found at PubChem are:
USAF EL-81, Benzylmethylamine hydrochloride, N-Benzylmethylamine hydrochloride, BENZYLAMINE, N-METHYL-, HYDROCHLORIDE, UNII-JQP1JP335I, JQP1JP335I, Benzenemethanamine, N-methyl-, hydrochloride, AC1L1A5C, benzyl(methyl)azanium chloride, SCHEMBL237384, methyl benzyl ammonium chloride, 103-67-3 (Parent), LS-43391, Benzenemethanamine, N-methyl-, hydrochloride (9CI), di-(Hydrogenated tallow) benzyl methyl ammonium chloride, 13426-94-3, N-Methylbenzylamine hydrochloride, N-methyl-1-phenylmethanamine hydrochloride, 61789-73-9, N-benzyl-methylaminehydrochloride, benzyl(methyl)amine hydrochloride, NCGC00095975-01, DSSTox_CID_26007, DSSTox_RID_81283, DSSTox_GSID_46007, CAS-13426-94-3, N-methyl-1-phenyl-methanamine Hydrochloride, methylbenzylamine, chloride, ARONIS23826, CHEMBL13952, SPECTRUM1400242, methylbenzylamine-hydrochlo-ride, Benzyl-Methyl-Ammonium Chloride, DTXSID1046007, BBC/108, CBSOFSBFHDQRLV-UHFFFAOYSA-N, MolPort-006-837-085, KS-00002B1D, n-benzyl-n-methylamine-hydrochloride, ZX-AS004328, Tox21_111541, 3855AD, SBB080534, AKOS005111049, Tox21_111541_1, CCG-214353, MCULE-8276463605, SS-3494, NCGC00166047-03, KB-79478, KB-258917, FT-0681809, A800781, I05-1714, I14-44823

ID: 317

InChIKey: CCOAINFUFGBHBA-UETGHTDLSA-N
SMILES: CN1CCCN=C1/C=C/C2=CC(=CC=C2)O.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281086
synonyms found at PubChem are:
Telopar, Oxantel embonate, 68813-55-8, Oxantel (pamoate), UNII-UPY1D732T0, Telopar (TN), Oxantel pamoate (USAN), Oxantel pamoate [USAN], UPY1D732T0, CP-14445, CP-14445-16, Oxanel pamoate, 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1), Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1) (salt), Oxantel Ebonate, EINECS 272-332-6, C13H16N2O.C23H16O6, D08PCE, CP 14,445-16, AC1NQY08, SCHEMBL601272, CHEBI:7821, SCHEMBL17801965, CHEBI:93155, HMS2093L04, Pharmakon1600-01505982, HY-B1344, Oxantel pamoate, analytical standard, NSC759296, AKOS026749864, CCG-213588, CS-5877, NSC-759296, (E)-m-(2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1) (salt), AN-38011, SBI-0206880.P001, Y0398, CP 14445-16, CP-14,445-16, D00806, C-54931, SR-05000001812, SR-05000001812-1, (E)-3-[2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] Salt, 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol, 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)vinyl]phenol, 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol, 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol

ID: 318

InChIKey: CCOJFDRSZSSKOG-SNVBAGLBSA-N
SMILES: C[C@H](C1=CC=C(C=C1)OC)C(=O)C2=C(C=C(C=C2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 821428
synonyms found at PubChem are:
ANGOLENSIN (R), (2r)-1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one, 4842-48-2, (?)-Angolensin, AC1LGHHG, Spectrum_000679, SpecPlus_000140, Spectrum2_000394, Spectrum3_000697, Spectrum4_001404, Spectrum5_000168, AC1Q5ED2, BSPBio_002453, KBioGR_001788, KBioSS_001159, SPECTRUM100616, DivK1c_006236, SPBio_000607, CHEMBL3039482, SCHEMBL12998482, CTK8E0206, KBio1_001180, KBio2_001159, KBio2_003727, KBio2_006295, KBio3_001673, DTXSID80356310, CHEBI:113545, ZINC338303, CCG-38665, SDCCGMLS-0066394.P001, NCGC00160149-01, NCGC00160149-02, AJ-19905, SR-05000002521, SR-05000002521-1, BRD-K98281970-001-02-6, BRD-K98281970-001-03-4, [R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)-1-propanone

ID: 319

InChIKey: CDBRNDSHEYLDJV-SBSPUUFOSA-M
SMILES: C[C@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 657352
synonyms found at PubChem are:
(R) -Naproxen sodium salt, Sodium (+)-6-methoxy-2-naphthylpropionate, UNM-0000305812, 30033-41-1, EINECS 250-008-5, Prestwick_1034, MLS002154002, CHEMBL1256284, Sodium (+)-6-methoxy-alpha-methyl-2-naphthaleneacetate, Naproxen sodium salt, USP grade, HMS2097O04, HMS2230B23, HMS3714O04, CCG-220791, SMR001233332, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, sodium salt, (+)-

ID: 320

InChIKey: CDKGGOUDHGSFAF-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1CNCCCCCCNCCCCCCCCNCCCCCCNCC2=CC=CC=C2OC.Cl.Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107759
synonyms found at PubChem are:
Methoctramine, Methoctramine tetrahydrochloride, 104807-46-7, UNII-RLO2T99XT3, RLO2T99XT3, METHOCTRAMINE HYDROCHLORIDE, CHEMBL500996, CHEBI:73452, N,N'-Bis(6-((2-methoxybenzyl)amino)hexyl)-1,8-octanediamine tetrahydrochloride, Methoctramine hemihydrate, 1,8-Octanediamine, N,N'-bis(6-(((2-methoxyphenyl)methyl)amino)hexyl)-, tetrahydrochloride, N,N'-Bis{6-[(2-methoxybenzyl)amino]hexyl}-1,8-octanediamine tetrahydrochloride, AC1L32PA, DTXSID40146754, Tox21_500862, CCG-222166, LP00862, NCGC00094187-01, NCGC00261547-01, KB-300124, LS-186869, EU-0100862, M-105, SR-01000075328, J-001258, SR-01000075328-1, N,N'-bis[6-[(2-methoxyphenyl)methylamino]hexyl]octane-1,8-diamine tetrahydrochloride, N,N'-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]1,8-octane diamine tetrahydrochloride, N,N'-bis{6-[(2-methoxybenzyl)amino]hexyl}octane-1,8-diamine tetrahydrochloride, N,N'-bis{6-[(2-methoxybenzyl)azaniumyl]hexyl}octane-1,8-diaminium tetrachloride, N1,N1'-(octane-1,8-diyl)bis(N6-(2-methoxybenzyl)hexane-1,6-diamine) tetrahydrochloride

ID: 321

InChIKey: CDMZOKMMANFJMU-UHFFFAOYSA-N
SMILES: CN1C2=C(N=C1C3=CC=C(C=C3)S(=O)(=O)O)N(C(=O)N(C2=O)CC=C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1365
synonyms found at PubChem are:
1-Allyl-3,7-dimethyl-8-sulfophenylxanthine, 1-Allyl-3,7-dimethyl-8-p-sulfophenylxanthine, 149981-25-9, CHEMBL88584, BENZENESULFONIC ACID,4-[2,3,6,7-TETRAHYDRO-3,7-DIMETHYL-2,6-DIOXO-1-(2-PROPEN-1-YL)-1H-PURIN-8-YL]-, 1-Allyl-3,7-dimethyl-8-sulfophenylxanthine sodium salt, 1-Allyl-3,7-dimethyl-8-p-sulfophenylxanthine Sodium Salt, NCGC00015008-01, Lopac-A-145, AC1L1BBE, Lopac0_000087, MLS000860020, SCHEMBL1319913, CTK5J4515, DTXSID80274303, HMS2235D11, HMS3260A16, HMS3371E10, ZINC2572274, Tox21_500087, BDBM50045344, MFCD00083167, AKOS015911418, CCG-204182, LP00087, NCGC00015008-02, NCGC00015008-03, NCGC00015008-04, NCGC00015008-05, NCGC00093591-01, NCGC00093591-02, NCGC00093591-03, NCGC00260772-01, SMR000326878, EU-0100087, FT-0607306, 1-Allyl-3,7-dimethyl-8-(p-sulfophenyl)xanthine, SR-01000075197, 1-Allyl-3,7-dimethyl-8-sulfophenylxanthine, solid, SR-01000075197-1, I14-39219, 4-(3,7-dimethyl-2,6-dioxo-1-prop-2-enylpurin-8-yl)benzenesulfonic acid, 4-(1-Allyl-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid, 4-(1-allyl-3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1h-purin-8-yl)benzenesulfonic acid

ID: 322

InChIKey: CDOSHBSSFJOMGT-JTQLQIEISA-N
SMILES: CC(=CCC[C@](C)(C=C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 443158
synonyms found at PubChem are:
(-)-Linalool, 126-91-0, (3R)-Linalool, (R)-(-)-Linalool, UNII-3U21E3V8I2, 1,6-Octadien-3-ol, 3,7-dimethyl-, (3R)-, CHEBI:28, (R)-3,7-dimethylocta-1,6-dien-3-ol, (3R)-3,7-dimethylocta-1,6-dien-3-ol, L-Linalool, 3U21E3V8I2, 3R,7-dimethylocta-1,6-dien-3-ol, LINALOOL (+), (R)-3,7-Dimethyl-1,6-octadien-3-ol, (R)-linalool, EINECS 204-811-2, laevo-linalool, (-)-3,7-dimethyl-1,6-octadien-3-ol, (3R)-3,7-dimethyl-1,6-octadien-3-ol, Linalool, (-)-, (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol, Spectrum_000212, SpecPlus_000909, Spectrum2_001944, Spectrum3_001173, Spectrum4_001777, Spectrum5_000393, 1,6-OCTADIEN-3-OL, 3,7-DIMETHYL-, (-)-, AC1L9E4Q, BSPBio_002785, KBioGR_002294, KBioSS_000692, DivK1c_007005, SCHEMBL891312, SPECTRUM1501212, SPBio_002007, CHEMBL235672, CTK8F1408, KBio1_001949, KBio2_000692, KBio2_003260, KBio2_005828, KBio3_002285, DTXSID40872607, MolPort-003-666-060, (-)-Linalool, analytical standard, ZINC1529820, CCG-38497, L-Linalool, natural, >=95%, FG, MFCD00135469, AKOS028109218, LMPR0102010013, SDCCGMLS-0066889.P001, SMP2_000331, NCGC00095658-01, NCGC00095658-02, CJ-23937, FT-0772303, 1,6-Octadien-3-ol,3,7-dimethyl-, (3R)-, C11388, J-005448, (-)-Linalool, >=95.0% (sum of enantiomers, GC), I14-45868, L-LINALOOL, REF. IND.-14<F128><144><F255>, UNII-D81QY6I88E component CDOSHBSSFJOMGT-JTQLQIEISA-N

ID: 323

InChIKey: CDRPUGZCRXZLFL-OWOJBTEDSA-N
SMILES: C1=CC(=C(C=C1/C=C/C2=CC(=CC(=C2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 667639
synonyms found at PubChem are:
piceatannol, 10083-24-6, 3-Hydroxyresveratol, astringinin, piceatanol, 3,3',4'5-Tetrahydroxystilbene, (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol, 3,5,3',4'-Tetrahydroxystilbene, 3,3',4,5'-Tetrahydroxystilbene, UNII-6KS3LS0D4F, 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol, NSC 365798, NSC 622471, NSC-365798, 6KS3LS0D4F, CHEMBL69863, 3,3',4,5'-Stilbenetetrol, 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol, CHEBI:28814, C14H12O4, NSC365798, NSC622471, 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-, 4339-71-3, 3,3',4,5'-Tetrahydroxy-trans-stilbene, 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-, (E)-, trans-3,3′,4,5′-Tetrahydroxystilbene, 3,3',4',5-tetrahydroxystilbene, 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,2-benzenediol, SMR001230734, SR-01000076056, MLS003171221, 4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol, Astringinine, 1,2-Benzenediol, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-, CCRIS 9289, (E)-Piceatannol, 3,3',4,5'-tetrahydroxy stilbene, Piceatannol, powder, AC1LDIIX, BiomolKI_000023, BiomolKI2_000031, D0O0VZ, AC1Q7B1B, Lopac0_000915, SCHEMBL43541, BSPBio_001120, MLS002153321, MLS006010974, BIDD:ER0001, SCHEMBL505561, BMK1-C11, cid_667639, MEGxp0_000245, DTXSID6040587, REGID_for_CID_667639, Stilbene-3,3',4,5'-tetrol, CHEBI:92460, ZINC14036, CDRPUGZCRXZLFL-OWOJBTEDSA-N, MolPort-001-740-425, HMS1362H21, HMS1792H21, HMS1990H21, HMS2236B03, HMS3262H12, HMS3403H21, ML027, Tox21_500915, 3,3'',4,5''-tetrahydroxystilbene, BDBM50045936, BS0146, GP2416, LMPK13090006, MFCD00221715, s3026, 3,4,3'',5''-tetrahydroxystillbene, AKOS015914951, AC-5281, AN-5100, CCG-100627, CS-5657, DB08399, FC-5001, LP00915, NSC-622471, RTX-010361, IDI1_002155, SMP2_000263, trans-3,3',4,5'-Tetrahydroxystilbene, 3',4',3,5-tetrahydroxy-trans-stilbene, 3,4,3',5'-tetrahydroxy-trans-stilbene, NCGC00094226-01, NCGC00094226-02, NCGC00094226-03, NCGC00094226-04, NCGC00094226-05, NCGC00094226-06, NCGC00094226-07, NCGC00261600-01, AK162486, AS-18099, HY-13518, SC-28783, 4-(3,5-dihydroxystyryl)benzene-1,2-diol, trans-3,3'',4,5''-tetrahydroxystilbene, 3,4,3'',5''-tetrahydroxy-trans-stilbene, AB0137762, AX8161462, LS-146872, LS-171757, EU-0100915, N2031, P1928, ST24035059, ST50825907, W2087, C05901, K00089, P 0453, 339P713, A800279, 1, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-, CU-00000000400-1, I14-6878, J-000228, SR-01000076056-1, SR-01000076056-6, SR-01000076056-9, BRD-K91509126-001-04-6, BRD-K91509126-001-05-3, (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol, F13BE9BB-B7D7-4D40-B31A-C15B953E033D, (E)-4-[2-(3,5-Dihydroxyphenyl)ethenyl]1,2-benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol, 4-[(1E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol, 5-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]benzene-1,3-diol, 4-[(E)-2-[3,5-bis(oxidanyl)phenyl]ethenyl]benzene-1,2-diol, 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol, 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol(Piceatannol), 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol(Piceatannol)

ID: 324

InChIKey: CDSMSBUVCWHORP-UHFFFAOYSA-N
SMILES: CC(=C)C1CCC(=CC1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1256
synonyms found at PubChem are:
Perillic acid, (-)-perillic acid, 7694-45-3, 4-Isopropenylcyclohex-1-enecarboxylic acid, EINECS 231-709-5, CHEBI:36999, 4-Isopropenyl-1-cyclohexene-1-carboxylic acid, perillate, 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid, 1-Cyclohexene-1-carboxylic acid, 4-(1-methylethenyl)-, perillic acid(-), 4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, SR-01000076076, NSC 667676, NSC-667676, L(-)-Perillic acid, AC1Q5RCJ, 4-isopropenylcyclohex-1-ene carboxylic acid, AC1L1B2K, AC1Q1J4P, 4-(2-propenyl)-1-cyclohexane-1-carboxylic acid, Lopac0_001001, SCHEMBL465998, CHEMBL1373981, CTK2H9028, CDSMSBUVCWHORP-UHFFFAOYSA-N, HMS3263I03, Tox21_501001, FCH831661, NSC641067, AKOS006230667, CCG-205081, LMPR0102090041, LP01001, MCULE-2236994087, NSC-641067, NCGC00015832-02, NCGC00015832-03, NCGC00015832-04, NCGC00015832-05, NCGC00015832-06, NCGC00094295-01, NCGC00094295-02, NCGC00094295-03, NCGC00094295-04, NCGC00261686-01, LS-57451, NCI60_013759, EU-0101001, FT-0693829, C11924, P 7083, C-47095, SR-01000076076-1, SR-01000076076-5, SR-01000076076-6, 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-, 4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic acid, 1A4758DA-6365-4FD5-BAEA-16032D3488FF

ID: 325

InChIKey: CEIXHRDGIFUDQQ-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)c(=O)n(c(n2)SCc3ccncc3)Cc4ccco4

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "W Namkung" "J Park" "Y Seo"

CID is 855743
synonyms found at PubChem are:
AC1LH2G9, Oprea1_445291, Oprea1_710553, AKOS002075949, EU-0028216, SR-01000563171, SR-01000563171-1, 3-(furan-2-ylmethyl)-2-(pyridin-4-ylmethylsulfanyl)quinazolin-4-one

ID: 326

InChIKey: CEKVGQOFHYOXSE-UHFFFAOYSA-N
SMILES: COC(=O)C1=CC(=C(C(=C1)Br)N)Br

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 11001350
synonyms found at PubChem are:
Methyl 4-amino-3,5-dibromobenzoate, 3282-10-8, CEKVGQOFHYOXSE-UHFFFAOYSA-N, SCHEMBL11425376, CTK4G9382, KS-00002AOS, DTXSID00451452, MolPort-001-769-392, 7061AJ, CM-843, ZINC16124430, AKOS015890738, AM84174, MCULE-2765968822, PS-7091, 2,6-Dibromo-4-(methoxycarbonyl)aniline, AJ-68341, KB-54286, 4CH-000260, FT-0648933, TL80090754, 3,5-Dibromo-4-aminobenzoic acid methyl ester, K-0039, 282M108, Benzoic acid,4-amino-3,5-dibromo-, methyl ester, Benzoic acid, 4-amino-3,5-dibromo-, methyl ester, I01-8162, Z1827897934

ID: 327

InChIKey: CEYTZVVSYBTFCX-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O.C1=CC(=N)C=CC1=C(C2=CC=C(C=C2)N)C3=CC=C(C=C3)N.C1=CC(=N)C=CC1=C(C2=CC=C(C=C2)N)C3=CC=C(C=C3)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11979709
synonyms found at PubChem are:
Tris(4-aminophenyl)carbonium pamoate, Tris(p-aminophenyl)carbonium pamoate, NSC 168367, 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) with tris-(p-aminophenyl)carbonium salt (1:2), 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) with tris-(p-aminophenyl)methylium salt (1:2), Methylium, tris(4-aminophenyl)-, 4,4'-methylenebis(3-hydroxy-naphthoate) (2:1), Tris(p-aminophenyl)carbonium salt with 4,4-methylenebis(3-hydroxy-2-naphthoic acid) (2:1), Tris(p-aminophenyl)methylium salt with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid) (2:1), 2706-47-0, Methylium, tris(4-aminophenyl)-, salt with 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) (2:1), Tris(4-aminophenyl)methylium, with 4,4'-methylenebis(3-hydroxy-2-naphthalene carboxylic acid)(2:1), LS-91415, Tris(p-aminophenyl)methylium salt with 4,4'-methylenebis[3-h, Methylium, tris(p-aminophenyl)-, 4,4'-methylenebis(3-hydroxy-2-naphthoate) (2:1), Methylium, tris(p-aminophenyl)-, 4,4'-methylenebis(3-hydroxy-2-naphthoate) (2:1) (8CI), UNII-4RJY69ERYU, 4RJY69ERYU, PARAROSANILINE PAMOATE ANHYDROUS, 7460-07-3, DTXSID50225569, 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy-, compd. with 4-((4-aminophenyl)(4-imino-2,5-cyclohexadien-1-ylidene)methyl)benzenamine, Alpha-(p-Aminophenyl)-alpha-(4-imino-2,5-cyclohexadien-1-ylidene)-p-toluidine 4,4'-methylenebis(3-hydroxy-2-naphthoate)

ID: 328

InChIKey: CFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1CC(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 547
synonyms found at PubChem are:
3,4-Dihydroxyphenylacetic acid, 102-32-9, Dopac, Homoprotocatechuic acid, 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, Dopacetic acid, Benzeneacetic acid, 3,4-dihydroxy-, 3,4-Dihydroxybenzeneacetic acid, Dihydroxyphenylacetic acid, 4-Carboxymethylcatechol, Homoprotocatechuate, 3,4-Dihydroxy-phenylacetic acid, (3,4-DIHYDROXYPHENYL)ACETIC ACID, Acetic acid, (3,4-dihydroxyphenyl)-, BA 2773, UNII-KEX5N0R4N5, CCRIS 3765, 3,4-dihydroxyphenyl acetic acid, 3,4-dihydroxyphenylacetate, EINECS 203-024-1, Lopac-D-9128, NSC 73191, BRN 2211017, KEX5N0R4N5, 3,4-DHPOP, AI3-52339, MLS001056737, CHEBI:41941, CFFZDZCDUFSOFZ-UHFFFAOYSA-N, 3,4-DIHYDROXYPHENYLCAETIC ACID, SMR000326727, DHY, 3,4-Dihydroxyphenylacetate, XV, (3,4-dihydroxyphenyl)acetate, HAA, Dopacetate, 3,4 Dihydroxyphenylacetic Acid, 3pcn, Dihydroxyphenylacetate, PubChem15519, PubChem24320, 1ai4, Catechol-4-acetic Acid, cid_547, 4-Carboxymethylpyrocatechol, bmse000329, D04UPU, Pyrocatechol-4-acetic Acid, 3,4-Dihydroxybenzeneacetate, AC1L19HD, AC1Q74WV, CHEMBL1284, NCIOpen2_000518, Lopac0_000414, SCHEMBL36348, KSC489O0J, ACMC-20981j, DOPAC; Homoprotocatechuic acid, Benzeneacetic acid,4-dihydroxy-, DTXSID9074430, Acetic acid,4-dihydroxyphenyl)-, BDBM52946, CTK3I9704, KS-00000CQW, 3,4-dihydroxy-Benzeneacetic acid, 3,4-dihydroxyl phenylacetic acid, BID2105, MolPort-001-790-954, ZX-AFC001494, HMS2233I20, HMS3261C10, HMS3373A01, KUC106695N, KUC106697N, ZINC388555, (3,4-dihydroxyphenyl)-Acetic acid, ACN-S003553, NSC73191, Tox21_500414, 3,4-DIHYDROXYPHENYLACETICACID, ANW-14693, MFCD00004338, NSC-73191, SBB064931, 3,4-Dihydroxyphenylacetic acid, 98%, AKOS015890264, 3,4-Dihydroxyphenylacetic acid polymer, AC-5292, AN-1120, CCG-204506, CD-1336, CS-W001080, DB01702, Dopac/(3,4-dihydroxyphenyl)-aceticaci, FCH1114657, HY-W001080, LP00414, MCULE-3883489471, MTB0002437, RS-1018, RTR-000594, TRA0061804, Acetic acid, (3,4-dihydroxyphenyl)-,, NCGC00015381-01, NCGC00015381-02, NCGC00015381-03, NCGC00015381-04, NCGC00015381-05, NCGC00093838-01, NCGC00093838-02, NCGC00093838-03, NCGC00261099-01, AJ-20686, AK-45471, BR-45471, KB-28329, KSC-11-207-5, KSC-11-207-8, LS-11781, SC-51734, SY015718, 2-[3,4-bis(oxidanyl)phenyl]ethanoic acid, AB0034449, AB1003740, AX8006414, Benzeneacetic acid, 3,4-dihydroxy- (9CI), ST2410266, TR-000594, 4CH-014740, AM20020093, D1283, EU-0100414, FT-0614331, ST45026883, X8606, C01161, D 9128, J10416, M-4413, C-04988, SR-01000075841, 3,4-Dihydroxyphenylacetic acid, analytical standard, I01-6366, J-000672, SR-01000075841-1, 47115C80-8C82-419A-BC51-B10A2CB7FE8F, 3,4-Dihydroxyphenylacetic acid ;Homoprotocatechuic acid; DOPAC, InChI=1/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12

ID: 329

InChIKey: CFKMVGJGLGKFKI-UHFFFAOYSA-N
SMILES: CC1=C(C=CC(=C1)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1732
synonyms found at PubChem are:
4-Chloro-3-methylphenol, 59-50-7, Chlorocresol, 4-Chloro-m-cresol, Parol, p-Chloro-m-cresol, Ottafact, Baktol, Phenol, 4-chloro-3-methyl-, 4-Chloro-3-cresol, Candaseptic, Baktolan, Parmetol, Peritonan, Raschit, Aptal, p-Chlorocresol, Rasen-Anicon, PCMC, Preventol CMK, Raschit K, p-Chlor-m-cresol, 4-Chloro-5-methylphenol, 2-Chloro-hydroxytoluene, Chlorcresolum, Chlorkresolum, Chlorocresolo, Chlorokresolum, 2-Chloro-5-hydroxytoluene, 3-METHYL-4-CHLOROPHENOL, 6-Chloro-3-hydroxytoluene, Perol, m-Cresol, 4-chloro-, Chloro-3-cresol, Parachlorometacresol, Rcra waste number U039, 4-Chloro-3-methyl phenol, Clorocresolo [DCIT], Clorocresol [Spanish], Caswell No. 185A, Chlorocresolum [Latin], Clorocresol [INN-Spanish], NSC 4166, Chlorocresolum [INN-Latin], CCRIS 1938, HSDB 5198, UNII-36W53O7109, 4-Chloro-1-hydroxy-3-methylbenzene, EINECS 200-431-6, 4-chloro-3-methyl-phenol, RCRA waste no. U039, EPA Pesticide Chemical Code 064206, BRN 1237629, AI3-00075, CHEBI:34395, CFKMVGJGLGKFKI-UHFFFAOYSA-N, NCGC00091338-01, 36W53O7109, DSSTox_CID_1717, DSSTox_RID_76291, DSSTox_GSID_21717, Chlorocresolum, Clorocresol, Clorocresolo, CAS-59-50-7, 4-chloro-meta-cresol, para-Chloro-meta-cresol, Chlorocresol [USAN:INN], Lysochlor, Chlorocresol [USAN:INN:NF], Chlorocresol, NF, Spectrum_000130, 2p7a, Chlorocresol (NF/INN), AC1Q7AEL, Spectrum2_000002, Spectrum4_000278, Spectrum5_000705, 4-chloro-5-methyl-phenol, WLN: QR DG C, EC 200-431-6, SCHEMBL12344, KBioGR_000776, KBioSS_000590, KSC490K6D, MLS002152924, BIDD:ER0169, DivK1c_000768, Phenol, 4-chloro-5-methyl-, SPECTRUM1500178, SPBio_000003, AC1L1C46, AC1Q2F77, ZINC1124, CHEMBL1230222, DTXSID4021717, 4-Chloro-3-methylphenol, 99%, CTK3J0561, HMS502G10, KBio1_000768, KBio2_000590, KBio2_003158, KBio2_005726, EBD9810, NSC4166, MolPort-001-770-144, NINDS_000768, HMS1920O03, HMS2091C14, HMS3652F13, Pharmakon1600-01500178, HY-B1284, KS-00000WI3, NSC-4166, 1-Chloro-2-methyl-4-hydroxybenzene, Tox21_111116, Tox21_201293, Tox21_300054, ANW-33283, CCG-39979, HSCI1_000352, LS-252, MFCD00002323, NSC756680, s4209, SBB060654, STL268900, 15733-22-9 (hydrochloride salt), AKOS000120242, Tox21_111116_1, CS-4678, MCULE-7719563630, NE10170, NSC-756680, RP20791, RTX-012283, TRA0096728, Chlorocresol (4-Chloro-3-methylphenol), IDI1_000768, NCGC00091338-02, NCGC00091338-03, NCGC00091338-04, NCGC00091338-06, NCGC00254021-01, NCGC00258845-01, 4-Chloro-3-methylphenol, technical grade, AC-14332, AJ-07966, AN-41790, BC207565, CJ-00030, KB-37916, Q208, SC-16335, SMR001224524, ZB000254, SBI-0051308.P003, AB1005448, KB-190664, TL8007001, 4-Chloro-3-methylphenol, analytical standard, B1696, FT-0618220, ST24043586, ST50823834, AZ0001-0105, 4-Chloro-3-methylphenol, >=98.0% (HPLC), C14331, D03468, AB00051939_02, AB00051939_03, SR-05000002033, 4-Chloro-3-methylphenol 100 microg/mL in Methanol, I01-1745, Q-200453, SR-05000002033-1, BRD-K89056082-001-03-6, F0001-1543, Z955123738, InChI=1/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H, 43M, 6-Chloro-3-hydroxytoluene; 2-Chloro-5-hydroxytoluene; 3-Methyl-4-chlorophenol; p-Chloro-m-cresol; 4-Chloro-m-cresol

ID: 330

InChIKey: CFOYWRHIYXMDOT-UHFFFAOYSA-N
SMILES: CCOC(=O)N1C=CN(C1=S)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 31072
synonyms found at PubChem are:
Carbimazole, 22232-54-8, Athyromazole, Carbimazol, Carbethoxymethimazole, Neomercazole, Carbinazole, Neo-Thyreostat, Basolest, Carbimazolum, Thyrostat, Neo-Mercazole, Atirozidina, Carbotiroid, Mertiran, Carbimazol spofa, Neo-Tireol, TYRAZOL, Carbimazolum [INN-Latin], Carbimazol [INN-Spanish, French], Ethyl 3-methyl-2-thioimidazoline-1-carboxylate, 1-Ethoxycarbonyl-3-methyl-2-thioxo-4-imidazoline, Carbimazole [INN:BAN:DCF], 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester, Carbimazole (INN), UNII-8KQ660G60G, 1-Ethoxycarbonyl-3-methyl-2-thioimidazol, CHEBI:617099, cg 1, Carbimazol henning (TN), EINECS 244-854-4, CG1, 3-Methyl-2-thioxo-4-imidazoline-1-carboxylic acid ethyl ester, Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate, 4-Imidazoline-1-carboxylic acid, 3-methyl-2-thioxo-, ethyl ester, BRN 0144339, CHEMBL508102, 8KQ660G60G, 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo, ethyl ester, ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate, NCGC00016760-01, CAS-22232-54-8, DSSTox_CID_2736, 3-methyl-1-ethoxycarbonylimidazoline-2-thione, DSSTox_RID_76708, DSSTox_GSID_22736, Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate, W-107493, ethyl 3-methyl-2-thioxo-4-imidazolinecarboxylate, SR-01000872660, Carbimazolo, Carbimazol henning, Prestwick_788, AC1L1KVD, Prestwick0_000439, Prestwick1_000439, Prestwick2_000439, Prestwick3_000439, Spectrum2_001251, Spectrum3_001968, D02CKX, Epitope ID:116890, AC1Q7F0E, SCHEMBL44211, BSPBio_000458, BSPBio_003568, 4-24-00-00064 (Beilstein Handbook Reference), MLS004734638, SPECTRUM1505323, SPBio_001182, SPBio_002397, BPBio1_000504, ZINC1091, DTXSID9022736, CTK3J2013, KBio3_002918, KS-00000FVA, CFOYWRHIYXMDOT-UHFFFAOYSA-N, MolPort-003-666-636, HMS1569G20, HMS1922D12, HMS2096G20, HMS3652G04, HMS3713G20, Pharmakon1600-01505323, BCP12935, HY-B0558, Tox21_110596, Tox21_302320, ANW-42276, BDBM50275889, CCG-39106, FCH918546, MFCD00027421, NSC758966, s4048, SBB058031, AKOS001647527, Tox21_110596_1, AC-8348, AM84794, AN-8076, API0001851, CS-2668, DB00389, MCULE-1170558032, NSC-758966, NCGC00016760-02, NCGC00016760-03, NCGC00016760-04, NCGC00016760-05, NCGC00016760-08, NCGC00095167-01, NCGC00095167-02, NCGC00177988-01, NCGC00177988-02, NCGC00255133-01, AS-13267, BC200548, CC-25401, H765, KB-48687, LS-79591, SC-80990, SMR001233183, ZB000245, SBI-0207026.P001, AB0013243, RT-000149, FT-0602919, ST50825250, C07615, D07616, ethyl 3-methyl-2-thioxo-imidazole-1-carboxylate, A816030, C-07519, I06-0843, SR-01000872660-1, SR-01000872660-2, BRD-K87156652-001-05-1, BRD-K87156652-001-06-9, ethyl 3-methyl-2-sulfanylidene-imidazole-1-carboxylate, 3-methyl-2-sulfanylidene-1-imidazolecarboxylic acid ethyl ester, Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate #, ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate, Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate, AldrichCPR, 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester Ethyl 3-methyl-2-thioimidazoline-1-carboxylate

ID: 331

InChIKey: CFPLLTGKDKZLIH-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C2=C1C(=O)OC3=C(O2)C(=C(C(=C3C)O)C(=O)O)C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 627044
synonyms found at PubChem are:
Hypoprotocetraric acid, 4665-02-5, 3,9-dihydroxy-1,4,7,10-tetramethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid, Coquimboic acid, KBio2_005898, Spectrum_000282, AC1LCEW3, Spectrum5_001851, KBioSS_000762, CTK1D8540, KBio2_000762, KBio2_003330, DTXSID80347869, CFPLLTGKDKZLIH-UHFFFAOYSA-N, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-, 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-, 3,8-Dihydroxy-1,4,6,9-tetramethyl-11-oxo-11H-dibenzo[b,E][1,4]dioxepine-7-carboxylic acid #, Benzoic acid, 3-(2-carboxy-5-hydroxy-3,6-dimethylphenoxy)-4,6-dihydroxy-2,5-dimethyl-, .epsilon.-lactone

ID: 332

InChIKey: CFTOTSJVQRFXOF-UHFFFAOYSA-N
SMILES: C1CNCC2=C1C3=CC=CC=C3N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107838
synonyms found at PubChem are:
Tryptoline, 16502-01-5, 2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole, Noreleagnine, 1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole, 1,2,3,4-Tetrahydro-beta-carboline, Tetrahydro-beta-carboline, THBC, Tetrahydronorharman, UNII-65027TMI0H, 1H,2H,3H,4H,9H-Pyrido[3,4-B]Indole, 1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-, 2,3,4,9-tetrahydro-1H-beta-carboline, MLS000069483, CHEMBL269236, 65027TMI0H, SMR000059115, Triptoline, Tetrahydronorharmane, 1,2,3,4-tetrahydrobeta-carboline, 1,2,3,4-tetrahydro-9H-pyrido(3,4-B)indole, 2,3,4,9-Tetrahydro-1H-pyrido(3,4-b)indole, 9H-1,2,3,4-Tetrahydropyrido(3,4-b)indole, PubChem16189, Spectrum_000575, Opera_ID_234, SpecPlus_000545, tetrahydro beta-carboline, Spectrum2_001379, Spectrum3_001413, Spectrum4_001858, Spectrum5_000396, D03LPH, AC1Q1H8A, Oprea1_032098, BSPBio_003086, KBioGR_002297, KBioSS_001055, MLS001076332, MLS001424178, BIDD:GT0403, DivK1c_006641, SCHEMBL171755, SPBio_001338, 1,2,3,4-tetrahydronorharmane, AC1L32U9, CHEBI:92568, CTK8B6239, KBio1_001585, KBio2_001055, KBio2_003623, KBio2_006191, KBio3_002306, DTXSID10167835, CFTOTSJVQRFXOF-UHFFFAOYSA-N, MolPort-000-150-262, HMS2052A05, HMS2235E21, HMS3370D07, HMS3394A05, ALBB-007680, CS-B1035, KS-00000GA0, 1,2,3,4-Tetrahydro-|A-carboline, 8380AA, ANW-53056, BBL027490, BDBM50130262, CCG-38855, MFCD00004954, SBB048967, STK501720, ZINC19418965, 58911-02-7 (mono-hydrochloride), AKOS004119465, ACN-000557, MCULE-6905321940, NC00329, QC-4504, TRA0023692, 2,3,4,9-Tetrahydro-1H-|A-carboline, 2,3,4,9-Tetrahydro-1H-beta-carbolin, NCGC00018148-01, NCGC00018148-02, NCGC00018148-03, NCGC00018148-04, NCGC00023426-03, AC-17176, AJ-73372, BC211315, CPD000059115, DS-16389, FS000806, KB-09915, SAM001246862, 1,2,3,4-tetrahydropyrido[3,4-b]indole, AB0072711, DB-043608, TC-010568, 4CH-021287, A3668, BB 0260537, FT-0637372, ST24038469, ST50947377, 1,2,3,4-tetrahydro-1H-pyrido[3,4-b]indole, N-8590, 1,2,3,4-Tetrahydro-9H-pyrido [3,4-b]indole, 1,2,3,4-tetrahydro-9H-pyrido-[3,4-b]indole, 1,2,3,4Tetrahydro-9H-pyrido [3,4-b] indole, 1,2,3,4-Tetrahydro-9H-pyrido [3,4-b] indole, 502T015, 9H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-, SR-01000000048, 1, 2, 3, 4-tetrahydro-9H-pyrido[3, 4-b]indole, SR-01000000048-4, 1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole, 98%, F2113-0962, InChI=1/C11H12N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-4,12-13H,5-7H

ID: 333

InChIKey: CGIBCVBDFUTMPT-RMKNXTFCSA-N
SMILES: COC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2OC)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5355469
synonyms found at PubChem are:
Flavokawain A, 3420-72-2, 2'-Hydroxy-4,4',6'-trimethoxychalcone, Flavokavain A, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, MLS002608040, (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, 37951-13-6, (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, flavokavin A, (E)-1-(2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, AC1NS7J0, CHEMBL243829, SCHEMBL2289181, SCHEMBL2289188, CGIBCVBDFUTMPT-RMKNXTFCSA-N, MolPort-003-803-645, NSC37445, ZINC4100760, BDBM50360495, MFCD00017174, NSC-37445, AKOS015915333, 4CN-1095, AJ-48054, AK112319, AN-25312, SMR001490973, ST059924, AX8075609, KB-173057, 2/'-Hydroxy-4,4/',6/'-trimethoxychalcone, ST24037115, W1242, 2'-Hydroxy-4,4',6'-trimethoxychalcone, 98%, J-019499, I14-54591, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-, 2 inverted exclamation marka-Hydroxy-4,4 inverted exclamation marka,6 inverted exclamation marka-trimethoxychalcone

ID: 334

InChIKey: CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3715
synonyms found at PubChem are:
indomethacin, indometacin, 53-86-1, Indocin, Indometacine, Indomethacine, Indocid, Metindol, Amuno, Indomethazine, Imbrilon, Tannex, Indomethacinum, Artracin, Artrinovo, Artrivia, Confortid, Idomethine, Indomecol, Indoptic, Indoptol, Inflazon, Infrocin, Metartril, Methazine, Mikametan, Reumacide, Sadoreum, Dolovin, Inacid, Indacin, Indomed, Indomee, Lausit, Metacen, Mobilan, Indo-rectolmin, Indo-tablinen, Inteban sp, Indometacyna, Indometicina, Mezolin, Indo-Lemmon, Indocin Sr, Indometacina, Indometacinum, Dolcidium, Durametacin, Elmetacin, Indomethine, Indorektal, Catlep, Indoxen, Vonum, Indo-phlogont, Chibro-amuno, Indomet 140, Rheumacin LA, Osmosin, Indmethacine, Indomethancin, Indomethegan, Arthrexin, Bonidin, Bonidon, Indameth, Indomod, Miametan, Indomo, Flexin continus, Hicin, Chrono-indicid, Chrono-indocid, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, Indometacyna [Polish], 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid, Bonidon Gel, Indometicina [Spanish], Dolcidium PL, Indo-Spray, Indolar SR, Indometacine [INN-French], Indometacinum [INN-Latin], Indometacina [INN-Spanish], 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, Liometacen, Novomethacin, CCRIS 3502, Aconip, HSDB 3101, Novo-Methacin, Apo-Indomethacin, Indocid Pda, Indocid Sr, NCI-C56144, Rhemacin LA, Indocin-SR, Indomethacin [USAN:BAN], UNII-XXE1CET956, Indochron E-R, Indocin I.V, Indocin (TN), Indocin I.V., Aconip (TN), 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, Indomethacin (USP), 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid, CHEMBL6, CGIGDMFJXJATDK-UHFFFAOYSA-N, Indocid (pharmaceutical), 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, EINECS 200-186-5, IN1454, Indomethacin & MAP-30, IMN, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, BRN 0497341, XXE1CET956, N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid, MLS000069402, Indomethacin (Indocid, Indocin), (1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid, CHEBI:49662, 1-(p-Chlorobenzoyl)-2-methoxy-3-methyl-1H-indole-3-acetic Acid, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, CAS-53-86-1, 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico, NCGC00015562-18, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, SMR000058195, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure [German], 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico [Spanish], DSSTox_CID_740, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy [Polish], I 7378, DSSTox_RID_75763, DSSTox_GSID_20740, 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, 1-[p-Chlorobenzoyl]-5-methoxy-2-methylindole-3-acetic acid, Tivorbex, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acid, FLAM, SR-01000000014, Indomethacin Hydrochloride, Indomethacin [USAN:USP], Indocollyre, Indonol, Innamit, Inteban, indomethacin HCl, 2-{1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl}acetic acid, 4kyk, Nu-Indo, Indomethacin,(S), Prestwick_597, Indocid (TN), Indometacin [INN], Indocin-SR (TN), Opera_ID_56, PubChem17620, Spectrum_000919, Tocris-1708, 1z9h, Indochron E-R (TN), AC1L1GJQ, Prestwick0_000272, Prestwick1_000272, Prestwick2_000272, Prestwick3_000272, Spectrum2_000970, Spectrum3_000468, Spectrum4_000018, Spectrum5_000868, Lopac-I-7378, D0R1RS, Indomethacin, 98% 5g, MolMap_000032, UPCMLD-DP023, EC 200-186-5, Indometacin (JP15/INN), Indometacin (JP17/INN), SCHEMBL9300, Lopac0_000692, Oprea1_686105, BSPBio_000144, BSPBio_001149, BSPBio_002176, KBioGR_000395, KBioGR_000489, KBioSS_000489, KBioSS_001399, 5-22-05-00239 (Beilstein Handbook Reference), KSC492C9L, MLS001074194, MLS006011845, ARONIS27005, BIDD:GT0132, DivK1c_000271, SPECTRUM1500350, SPBio_000979, SPBio_002363, BPBio1_000160, GTPL1909, DTXSID9020740, Indomethacin, >=99% (TLC), UPCMLD-DP023:001, BDBM17638, CGIGDMFJXJATDK-UHFFFAOYSA-, CTK3J2195, HMS500N13, KBio1_000271, KBio2_000489, KBio2_001399, KBio2_003057, KBio2_003967, KBio2_005625, KBio2_006535, KBio3_000897, KBio3_000898, KBio3_001396, KS-00000WRK, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure, MolPort-000-917-894, NINDS_000271, Bio2_000405, Bio2_000885, HMS1362I11, HMS1568H06, HMS1792I11, HMS1920F21, HMS1990I11, HMS2089N19, HMS2091N09, HMS2095H06, HMS2231J10, HMS3262K05, HMS3268A14, HMS3374F07, HMS3403I11, HMS3430L03, HMS3649K17, HMS3655O04, HMS3712H06, Pharmakon1600-01500350, ZINC601283, ACT02579, BCP18951, Indomethacin, >=99.0% (TLC), 7681-54-1 (hydrochloride salt), Tox21_113109, Tox21_201791, Tox21_300266, Tox21_500692, AC-532, ANW-42683, CCG-40186, LS-187, MFCD00057095, NSC757061, s1723, SBB057417, STL257874, AKOS000592893, Tox21_113109_1, CS-2242, DB00328, Indometacin 1.0 mg/ml in Acetonitrile, KS-5255, LP00692, MCULE-5636486088, NE11089, NSC-757061, RTR-019032, IDI1_000271, IDI1_002160, KS-000048I8, NCGC00015562-01, NCGC00015562-02, NCGC00015562-03, NCGC00015562-04, NCGC00015562-05, NCGC00015562-06, NCGC00015562-07, NCGC00015562-08, NCGC00015562-09, NCGC00015562-10, NCGC00015562-11, NCGC00015562-12, NCGC00015562-13, NCGC00015562-14, NCGC00015562-15, NCGC00015562-16, NCGC00015562-17, NCGC00015562-19, NCGC00015562-20, NCGC00015562-21, NCGC00015562-22, NCGC00015562-24, NCGC00015562-25, NCGC00024135-02, NCGC00024135-04, NCGC00024135-05, NCGC00024135-06, NCGC00024135-07, NCGC00024135-08, NCGC00024135-09, NCGC00024135-10, NCGC00024135-11, NCGC00024135-12, NCGC00024135-13, NCGC00024135-14, NCGC00024135-15, NCGC00254075-01, NCGC00259340-01, NCGC00261377-01, AJ-23672, AN-15738, BC203259, BP-30207, H911, HY-14397, KB-74685, LS-82147, NCI60_041708, SC-17536, SBI-0050670.P004, AB1009492, TR-019032, AB00052022, EU-0100692, FT-0603227, I0655, ST24039048, ST50320042, Indomethacin, meets USP testing specifications, BIM-0050670.0001, C01926, D00141, J10170, S00108, 74252-25-8 (hydrochloride salt, tri-hydrate), AB00052022-20, AB00052022-21, AB00052022_23, AB00052022_24, L000959, Indomethacin, Antibiotic for Culture Media Use Only, Q-201239, SR-01000000014-2, SR-01000000014-4, SR-01000000014-6, BRD-K57222227-001-06-1, BRD-K57222227-001-18-6, BRD-K57222227-001-27-7, SR-01000000014-10, SR-01000000014-16, Z56784896, 1-p-chlorobenzoyl-2-methyl-5-methoxyindol-3-acetic acid, 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indoleacetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid, 1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetic acid, 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid, 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid, Indomethacin, European Pharmacopoeia (EP) Reference Standard, N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, Indomethacin, United States Pharmacopeia (USP) Reference Standard, .alpha.-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid #, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid & MAP-30, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- (9CI), 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2 methylindol-3-yl}acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2methylindol-3-yl}acetic acid, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI), Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin, Indomethacin, Indomethacin, Pharmaceutical Secondary Standard; Certified Reference Material, 37242-43-6, 503560-73-4, 87377-08-0, 91853-74-6, InChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)

ID: 335

InChIKey: CGQCWMIAEPEHNQ-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(=C1)C(C(=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1245
synonyms found at PubChem are:
Vanillylmandelic acid, 55-10-7, Vanilmandelic acid, dl-4-Hydroxy-3-methoxymandelic acid, 2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetic acid, 4-HYDROXY-3-METHOXYMANDELIC ACID, 2394-20-9, Vanillomandelic acid, (+/-)-Vanillylmandelic acid, VMA, alpha,4-Dihydroxy-3-methoxybenzeneacetic acid, CHEBI:20106, CGQCWMIAEPEHNQ-UHFFFAOYSA-N, Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-, HMMA, Mandelic acid, 4-hydroxy-3-methoxy-, H-6500, 2-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)acetic acid, 2-(3-methoxy-4-oxidanyl-phenyl)-2-oxidanyl-ethanoic acid, 3-methoxy-4-hydroxymandelic acid, Vanillinmandelic Acid, DL-vanillomandelic acid, DL-vanillylmandelic acid, 4-Hydroxy-3-methoxymandelate, 4'-Hydroxy-3'-methoxymandelic acid, dl-3-Methoxy-4-hydroxymandelic acid, 3-Methoxy-4-hydroxymandelate, 4-Hydroxy-3-methoxy-DL-mandelic acid, (4-Hydroxy-3-methoxyphenyl)glycolic acid, Benzeneacetic acid, alpha,4-dihydroxy-3-methoxy-, EINECS 200-224-0, 3-Methoxy-4-hydroxyphenylhydroxyacetic acid, (y)-Vanillylmandelic acid, Ia(2)Y+/-aIOEa, (?)-Vanillylmandelic acid, D0D8XF, AC1L1B1N, AC1Q46AA, Lopac0_000602, Oprea1_553862, MLS002153465, Adrenaline Related Compound 2, SCHEMBL134326, (.+/-.)-Vanilmandelic acid, GTPL6645, CHEMBL1256396, SCHEMBL10085823, KS-00000XSU, MolPort-001-793-004, HMS2235H06, HMS3261J06, HMS3371D20, Tox21_500602, 8088AF, RW1285, SBB017532, 4-hydroxy-3-methoxyphenylglycolic acid, AKOS015851906, ACM2394209, CCG-204691, FCH1116797, LP00602, MCULE-9059916420, VC30856, NCGC00015492-02, NCGC00015492-03, NCGC00015492-04, NCGC00015492-05, NCGC00093978-01, NCGC00093978-02, NCGC00093978-03, NCGC00261287-01, AK126477, AN-20784, AN-24421, SC-87649, SMR001230822, ST088606, 3-(1/4)xNo>>u-4-oC>>u+/-aIOEa, 4-oC>>u-3-(1/4)xNo>>u+/-aIOEa, AX8006743, TR-037065, EU-0100602, FT-0634243, FT-0669752, DL-4-HYDROXY-3-METHOXY-MANDELIC ACID, Hydroxy(4-hydroxy-3-methoxyphenyl)acetic acid, ( inverted question mark)-Vanillylmandelic acid, C05584, H 0131, Hydroxy(4-hydroxy-3-methoxyphenyl)acetic acid #, 055H107, A817001, dl-.alpha.,4-Dihydroxy-3-methoxyphenylacetic acid, SR-01000075241, 2-(4-Hydroxy-3-methoxyphenyl)-2-hydroxyacetic acid, 2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)aceticacid, SR-01000075241-1, I14-92182, 2-(4'-Hydroxy-3'-methoxyphenyl) 2-hydroxyethanoic acid, 2-(4'-hydroxy-3'-methoxyphenyl)-2-hydroxyethanoic acid, DCD57880-FBEE-4ED4-A834-92387D266E8A, DL-4-Hydroxy-3-methoxymandelic acid, analytical standard, ( inverted question mark)-4-Hydroxy-3-methoxymandelic acid, 4-oC>>u-3-(1/4)xNo>>u inverted question markaEthOEEEa, DL-4-Hydroxy-3-methoxymandelic acid, >=98% (TLC), powder

ID: 336

InChIKey: CGWOIDCAGBKOQL-UHFFFAOYSA-N
SMILES: CC(C)(C)NC(=O)C1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC4=CC(=C(C=C4C(=N3)N)OC)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10098248
synonyms found at PubChem are:
L-765,314, NCGC00094440-01, Lopac0_001186, SCHEMBL8704241, CHEMBL1322702, CCG-205260, LP01186, NCGC00015604-02, NCGC00015604-03, NCGC00015604-04, NCGC00094440-02, EU-0101186, L 3040, L016366, SR-01000076155, SR-01000076155-1, (2S)-4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-2-[[(1,1-Dimethylethyl)amino]carbonyl]-1-piperazinecarboxylic acid, phenylmethyl ester

ID: 337

InChIKey: CHDPSNLJFOQTRK-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 107952
synonyms found at PubChem are:
Betaxolol hydrochloride, 63659-19-8, Betaxolol HCL, Betoptima, Kerlone, Lokren, Betoptic, Kerlon, Betaxolo Hydrochloride, Betoptic S, Betaxolol (hydrochloride), alo 1401-02, EINECS 264-384-3, MLS000863279, SL 75 212-10, Betaxolol hydrochloride (Betoptic), CPD000058420, SMR000058420, Betoptic (TN), Kerlone (TN), SL 75.212-10, (+-)-1-(p-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propanol hydrochloride, 1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-ol hydrochloride, 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride, Q-200714, 1-(Isopropylamino)-3-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)propan-2-ol hydrochloride, 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-, hydrochloride, (+-)-, CHEBI:643228, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol hydrochloride, SR-01000000108, SL-75212-10, Kerlong, Betaxolol hydrochloride [USAN], 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol;hydrochloride, Prestwick_779, Betaxolol hydrochloride [USAN:USP:JAN], Betaxolol(hydrochloride), Opera_ID_878, Lokren ,Kerlone ;Betoptic, AC1Q3DQ4, CHEMBL1691, SCHEMBL42794, MLS000028464, MLS000758269, MLS001148209, MLS001424199, MLS002222261, AC1L331T, CTK8F0839, HY-B0381A, MCI-144, CHDPSNLJFOQTRK-UHFFFAOYSA-N, MolPort-003-666-823, HMS1569M05, Pharmakon1600-01505512, 63659-18-7 (Parent), BCP02967, Tox21_500193, Betaxolol hydrochloride (JP17/USP), BG0105, MFCD00242959, NSC760048, AKOS015843993, AC-1412, API0001701, BCP9000394, CCG-101057, CCG-213473, CS-2453, LP00193, NC00307, NSC-760048, Betaxolol hydrochloride, >98% (HPLC), KS-00001F73, NCGC00093669-01, NCGC00093669-02, NCGC00260878-01, AN-14973, AS-18082, BC227944, SAM001247084, BCP0726000249, AB2000314, LS-122006, TC-071428, B4474, EU-0100193, FT-0645228, S1827, W0012, B 5683, D00598, 659X198, A803574, I06-1154, SR-01000000108-2, SR-01000000108-4, SR-01000000108-9, Betaxolol hydrochloride, European Pharmacopoeia (EP) Reference Standard, Betaxolol hydrochloride, United States Pharmacopeia (USP) Reference Standard, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)propan-2-ol hydrochloride, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)-2-propanol hydrochloride, 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanolhydrochloride, Betaxolol for peak identification, European Pharmacopoeia (EP) Reference Standard, 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-,hydrochloride, 72424-72-7, AC1LCWB4, AKOS026749833, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol; hydron; chloride, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol hydrochloride, 1-(p-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propanol hydrochloride, 3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxy-N-(propan-2-yl)propan-1-aminium chloride, 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol hydrochloride, MolPort-005-977-072, MCULE-2260668292, 1-[4-(2-Cyclopropylmethoxy-ethyl)-phenoxy]-3-isopropylamino-propan-2-ol; hydrochloride

ID: 338

InChIKey: CHNXZKVNWQUJIB-CEGNMAFCSA-N
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5284557
synonyms found at PubChem are:
ethisterone, 434-03-7, Pregneninolone, 17alpha-Ethynyltestosterone, Ethynyltestosterone, Aethisteronum, Ethisteronum, Etisterona, Ethinyl testosterone, Aethisteron, Anhydrohydroxyprogesterone, Nugestoral, Progestoral, UNII-P201BVY1MJ, 17alpha-Ethinyltestosterone, Anhydroxyprogesterone, 17alpha-Ethinyl testosterone, Progestolets, Syngestrotabs, Ethinone, Prodroxan, Produxan, Progestab, Trosinone, Ora-Lutin, Ethinyltestosterone, P201BVY1MJ, Praegninum, Colutoid, Gestoral, Nalutoral, Pregnin, Prodoxan, Prolutol, Prone, Lucorteum Oral, MLS000069396, CHEMBL241694, Lutidon Oral, Progestin P, Primolut C, Proluton C, CHEBI:34749, (17alpha)-17-hydroxypregn-4-en-20-yn-3-one, 17alpha-Ethynyl-17beta-hydroxyandrost-4-en-3-one, Etisterone [DCIT], 17-beta-Hydroxy-17-alpha-ethynyl-4-androsten-3-one, 17-Ethinyltestosterone, SMR000058320, 17-Ethinyl testosterone, DSSTox_CID_3016, Ethisteronum [INN-Latin], Etisterona [INN-Spanish], 17-Ethynyl-17beta-hydroxyandrost-4-en-3-one, Testosterone, 17-ethynyl-, 17-alpha-Ethynyltestosterone, DSSTox_RID_76831, DSSTox_GSID_23016, (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, Etisterone, NSC 9565, EINECS 207-096-5, Ethisterone anhydrohydroxyprogesterone, BRN 1889895, AI3-26421, 17-Hydroxy-17-alpha-pregn-4-en-20-yn-3-one, Androst-4-en-3-one, 17alpha-ethynyl-17-hydroxy-, Ethisterone [INN:BAN:NF], NCGC00095023-01, NCGC00159363-02, CAS-434-03-7, 17 beta-Hydroxy-4,17alpha-pregnen-20-yn-3-one, AC1NR4OD, 17-alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy-, Opera_ID_1078, Prestwick3_000261, EC 207-096-5, SCHEMBL24475, BSPBio_000102, 4-08-00-01225 (Beilstein Handbook Reference), MLS001076282, BPBio1_000114, DTXSID2023016, Ethisterone, >=99% (HPLC), CHNXZKVNWQUJIB-CEGNMAFCSA-N, MolPort-002-507-150, HMS2090E14, HMS2095F04, HMS2234J08, HMS3712F04, (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, BCP23355, HY-B0487, ZINC3881635, Tox21_111393, Tox21_111604, Tox21_302324, BBL028141, BDBM50198711, MFCD00003656, s2611, STK801873, AKOS005622724, Tox21_111604_1, AC-2170, BCP9000664, CCG-220261, CS-2603, MCULE-2690578106, NCGC00021466-03, NCGC00021466-05, NCGC00255184-01, AS-13381, I034, BCP0726000218, AB2000700, 4,17alpha-Pregnen-17beta-ol-20-yn-3-one, AB00490005, B1502, E0040, 17-hydroxy-17alpha-pregn-4-en-20-yn-3-one, C14487, 17beta-Hydroxy-4,17alpha-pregnen-20-yn-3-one, AB00384255-11, AB00384255-13, AB00384255_14, Ethisterone, VETRANAL(TM), analytical standard, 434E037, A826270, SR-01000002984, 17alpha-ethynyl-17beta-hydroxy-androst-4-en-3-one, SR-01000002984-2, BRD-K03981224-001-02-9, 17alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy- (8CI), Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17-alpha)- (9CI), Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)- (9CI), (8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-17-oxidanyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, (8R,9S,10R,13S,14S,17S)-17-ethynyl-17-hydroxy-10,13-dimethyl-1,7,8,10,11,12,13,15,16,17-decahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one

ID: 339

InChIKey: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
SMILES: C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54670067
synonyms found at PubChem are:
l-ascorbic acid, ascorbic acid, vitamin C, 50-81-7, L(+)-Ascorbic acid, L-ascorbate, Ascorbicap, Cevitamic acid, ascorbate, Ascoltin, Hybrin, Allercorb, Ascorbajen, Ascorbutina, Ascorteal, Cescorbat, Cetemican, Cevitamin, Citriscorb, Laroscorbine, Lemascorb, Natrascorb, Proscorbin, Roscorbic, Secorbate, Testascorbic, Vitacimin, Vitamisin, Vitascorbol, Ascorin, Ascorvit, Cantaxin, Cebicure, Cebione, Cegiolan, Ceglion, Celaskon, Cemagyl, Cenetone, Cenolate, Cergona, Cetamid, Cevalin, Cevatine, Cevimin, Cevital, Cevitan, Cevitex, Colascor, Concemin, Redoxon, Vicelat, Viforcit, Viscorin, Vitacee, Vitacin, Adenex, Ascorb, Cantan, Cebid, Cebion, Cecon, Celin, Cemill, Cereon, Cevex, Ciamin, Cipca, Hicee, Ribena, Vitace, Xitix, Davitamon C, Arco-cee, Planavit C, Catavin C, Ce lent, Liqui-Cee, Vicomin C, Cee-Vite, Cevi-Bid, Scorbu-C, C-Level, C-Vimin, Cetane-Caps TD, Duoscorb, Scorbacid, Cewin, Antiscorbic vitamin, C-Long, C-Quin, C-Span, Meri-C, Cee-Caps TD, L-Lyxoascorbic acid, L-Xyloascorbic acid, Antiscorbutic vitamin, Cetane-Caps TC, Acidum ascorbinicum, 3-Oxo-L-gulofuranolactone, Ce-Mi-Lin, IDO-C, Natrascorb injectable, Acidum ascorbicum, L-(+)-Ascorbic Acid, CE-VI-Sol, Ferrous ascorbate, Ascor-B.I.D., Acido ascorbico, Acide ascorbique, Dora-C-500, Kyselina askorbova, 3-Keto-L-gulofuranolactone, Ascorbicab, Cortalex, Ferancee, Stuartinic, Tolfrinic, Antiscorbutic factor, L-3-Ketothreohexuronic acid lactone, L-Threoascorbic acid, Chromagen, Magnorbin, Cetebe, Kyselina askorbova [Czech], Caswell No. 061B, Vicin, Acide ascorbique [INN-French], Acido ascorbico [INN-Spanish], Acidum ascorbicum [INN-Latin], Semidehydroascorbate, Sodascorbate, Ascorbicin, Magnesium Ascorbicum, (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, NCI-C54808, L-threo-Hex-2-enonic acid, gamma-lactone, L-threo-Ascorbic acid, cevibid, Ascorbinsaeure, Sunkist, Ascorbic Acid, Monosodium Salt, 3-Oxo-L-gulofuranolactone (enol form), roscorbi c, Acid Ascorbic, UNII-PQ6CK8PD0R, Oral Vitamin C, ascor-b.i.d, Ascorbicap (TN), CCRIS 57, Ascoltin (TN), antiscorbic vita min, Ascorbin, FEMA No. 2109, component of Cortalex, component of Ferancee, HSDB 818, [14C]ascorbic acid, Ascorbic acid [BAN:INN:JAN], Ascorbic acid [INN:BAN:JAN], [14C]-ascorbic acid, Hex-2-enonic acid gamma-lactone, L-threo-, ascorbic acid (vit C), EINECS 200-066-2, NSC 33832, Iron(II) ascorbate, PQ6CK8PD0R, Iron-ascorbic acid complexes, L-3-ketothreohexuronic acid, component of E and C-Level, component of Endoglobin Forte, CHEBI:29073, Sodium Ascorbate (Ascorbic Acid), L-threo-hex-2-enono-1,4-lactone, L-Ascorbic acid, free radical form, (+)-Ascorbic acid, NCGC00164357-01, E300, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one, DSSTox_CID_106, DSSTox_RID_75370, Ascorbinsaure, DSSTox_GSID_20106, Kangbingfeng, Chewcee, Citrovit, Juvamine, Ceklin, CALCIUM ASCORBATE, Vasc, (+)-Sodium L-ascorbate, Rovimix C, Scorbu C, Parentrovite, Cell C, (2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one, Viscorin 100M, (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one, 1-Xyloascorbic Acid, Ronotec 100, Suncoat VC 40, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one, Rontex 100, Xyloascorbic acid, L-, 89924-69-6, L-Threoascorbic acid,Antiscorbutic factor,Vitamin C;(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, 3-Keto-1-Gulofuranolactone, L-Ascorbic acid, meets USP testing specifications, 2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one, Cevitamate, Ascor, L-lyxoascorbate, L-xyloascorbate, .Ascorbinsaure, vitamin-c, L-AscorbicAcid, Vitamin B mixture with vitamin C, 3eka, cee-caps td, Ester C, Ester-C, l-threo-hex-1-eofuranos-3-ulose, (+)-ascorbate, L(+)-ascorbate, L-(+)-ascorbate, Ascorbic acid [USP:INN:BAN:JAN], Ascorbic acid mixture with Vitamin B, Vitamin C,(S), E 300, 178101-88-7, PubChem18445, Ascorbic Acid DC97SF, Prestwick3_000325, L-Ascorbic acid, 99%, Ascorbic Acid mixture with Vitamin B Complex, SCHEMBL785, bmse000182, D06NNE, D07AHW, D0U4HT, Vitamin C (Ascorbic acid), AC1L1L4T, SCHEMBL4430, L-Ascorbic acid, FCC, FG, BSPBio_000329, KSC925A7P, MLS002153776, CHEMBL40274, AC1Q77S6, BPBio1_000363, GTPL4532, GTPL4781, L-Ascorbic acid, reagent grade, DTXSID5020106, L-Ascorbic acid, >=99.0%, CTK8C5077, 134-03-2 (monosodium salt), BIA0602, Ascorbic acid (JP15/USP/INN), Ascorbic acid (JP17/USP/INN), CIWBSHSKHKDKBQ-JLAZNSOCSA-N, MolPort-001-792-501, ZX-AFC000785, HMS2096A11, HMS2231N16, HMS3713A11, 1129294-89-8, 154170-90-8, BCP27915, HY-B0166, KS-00000EU9, Tox21_110315, Tox21_112104, Tox21_202127, Tox21_302958, ANW-73969, gamma-lactone L-threo-Hex-2-enonate, L-Ascorbic acid, analytical standard, L-Ascorbic acid, AR, >=99.5%, LS-145, MFCD00064328, s3114, Tox21_112104_1, ZINC100006770, ZINC100019304, CCG-207946, DB00126, FCH1121413, L-Ascorbic acid, mixt. with vitamin B, RP23765, RTR-032643, VIT0000113, gamma-lactone L-threo-Hex-2-enonic acid, L-Ascorbic acid, ACS reagent, >=99%, NCGC00091517-01, NCGC00091517-02, NCGC00091517-03, NCGC00091517-06, NCGC00188972-01, NCGC00256504-01, NCGC00259676-01, 14536-17-5, 53262-66-1, AK-96407, BP-12831, SC-18563, SMR001233160, L-Ascorbic acid, plant cell culture tested, AB0010512, AB1002440, AX8021086, L-Ascorbic acid, reagent grade, crystalline, A0537, A8158, AB00376923, Ascorbic Acid (L-Ascorbic Acid; Vitamin C), E-300, ST24026436, L-Ascorbic acid, BioUltra, >=99.5% (RT), L-Ascorbic acid, tested according to Ph.Eur., 3466-EP2269610A2, 3466-EP2269978A2, 3466-EP2269985A2, 3466-EP2269988A2, 3466-EP2269991A2, 3466-EP2270000A1, 3466-EP2270002A1, 3466-EP2270008A1, 3466-EP2270011A1, 3466-EP2270505A1, 3466-EP2272516A2, 3466-EP2272537A2, 3466-EP2272822A1, 3466-EP2272834A1, 3466-EP2272835A1, 3466-EP2272844A1, 3466-EP2275413A1, 3466-EP2277848A1, 3466-EP2277865A1, 3466-EP2281823A2, 3466-EP2284149A1, 3466-EP2284150A2, 3466-EP2284151A2, 3466-EP2284152A2, 3466-EP2284153A2, 3466-EP2284155A2, 3466-EP2284156A2, 3466-EP2284164A2, 3466-EP2284171A1, 3466-EP2284178A2, 3466-EP2284179A2, 3466-EP2287140A2, 3466-EP2287148A2, 3466-EP2287150A2, 3466-EP2287153A1, 3466-EP2287156A1, 3466-EP2289510A1, 3466-EP2289883A1, 3466-EP2289890A1, 3466-EP2289892A1, 3466-EP2292227A2, 3466-EP2292228A1, 3466-EP2292592A1, 3466-EP2292612A2, 3466-EP2292617A1, 3466-EP2295055A2, 3466-EP2295401A2, 3466-EP2295409A1, 3466-EP2295416A2, 3466-EP2295419A2, 3466-EP2295426A1, 3466-EP2295427A1, 3466-EP2295435A1, 3466-EP2298735A1, 3466-EP2298742A1, 3466-EP2298748A2, 3466-EP2298768A1, 3466-EP2298770A1, 3466-EP2298776A1, 3466-EP2301536A1, 3466-EP2301538A1, 3466-EP2301929A1, 3466-EP2301931A1, 3466-EP2301935A1, 3466-EP2301940A1, 3466-EP2305219A1, 3466-EP2305257A1, 3466-EP2305636A1, 3466-EP2305637A2, 3466-EP2305648A1, 3466-EP2305651A1, 3466-EP2305668A1, 3466-EP2305674A1, 3466-EP2305679A1, 3466-EP2305683A1, 3466-EP2308854A1, 3466-EP2308857A1, 3466-EP2308861A1, 3466-EP2308867A2, 3466-EP2308870A2, 3466-EP2311453A1, 3466-EP2311455A1, 3466-EP2311805A1, 3466-EP2311807A1, 3466-EP2311809A1, 3466-EP2311824A1, 3466-EP2311839A1, 3466-EP2311842A2, 3466-EP2314295A1, 3466-EP2314584A1, 3466-EP2314585A1, 3466-EP2314588A1, 3466-EP2314589A1, 3466-EP2314590A1, 3466-EP2314593A1, 3466-EP2316452A1, 3466-EP2316457A1, 3466-EP2316458A1, 3466-EP2316470A2, 3466-EP2316825A1, 3466-EP2316826A1, 3466-EP2316827A1, 3466-EP2316828A1, 3466-EP2316832A1, 3466-EP2316833A1, 3466-EP2316837A1, 3466-EP2374792A1, 3466-EP2377510A1, 3466-EP2380568A1, C 1000, C00072, D00018, L-Ascorbic acid, p.a., ACS reagent, 99.0%, 93398-EP2380568A1, AB00376923_04, AB00376923_05, L-Ascorbic acid, JIS special grade, >=99.0%, L-Ascorbic acid, Vetec(TM) reagent grade, 99%, L-Ascorbic acid, BioXtra, >=99.0%, crystalline, L-Ascorbic acid, puriss. p.a., >=99.0% (RT), L-Threoascorbic acid, Antiscorbutic factor, Vitamin C, L-Threoascorbic acid; Antiscorbutic factor; Vitamin C, 47A605F0-4187-47A8-B0CE-F9E7DA1B0076, L-Ascorbic acid, p.a., ACS reagent, reag. ISO, 99.7%, Ascorbic acid, British Pharmacopoeia (BP) Reference Standard, Ascorbic acid, European Pharmacopoeia (EP) Reference Standard, L-Ascorbic acid, certified reference material, TraceCERT(R), L-Ascorbic acid, powder, cell culture tested, gamma-irradiated, 3,4-Dihydroxy-5beta-[(S)-1,2-dihydroxyethyl]furan-2(5H)-one, Ascorbic acid, United States Pharmacopeia (USP) Reference Standard, L-Ascorbic acid solution, 1.0 mg/mL in acetonitrile: water, certified reference material, L-Ascorbic acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%, L-Ascorbic acid, suitable for cell culture, suitable for plant cell culture, >=98%, 1018124-03-2, 129940-97-2, 1428525-25-0, 1703051-92-6, 259133-78-3, 30208-61-8, 50976-75-5, 56172-55-5, 56533-05-2, 57304-74-2, 57606-40-3, 623158-95-2, 882690-91-7, 884381-69-5, 885512-24-3, 88845-26-5, L-Ascorbic Acid (Vitamin C)-13C6 solution, 500 mug/mL in acetonitrile: water, certified reference material, ampule of 1 mL, L-Ascorbic acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.7-100.5% (oxidimetric), Valeryl fentanyl hydrochloride solution, 100 mug/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL

ID: 340

InChIKey: CJCSPKMFHVPWAR-JTQLQIEISA-N
SMILES: C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 38853
synonyms found at PubChem are:
methyldopa, 555-30-6, Alphamethyldopa, Aldomet, Alpha medopa, Dopamet, l-alpha-Methyldopa, alpha-Methyl dopa, Baypresol, Hyperpax, Presolisin, Sedometil, Sembrina, Dopegyt, Medomet, Methyl dopa, Methyldopa anhydrous, Dopamethyperpax, Aldometil, Grospisk, Medopren, Methoplain, Presinol, Becanta, Dopatec, Hypolag, Medopa, Medopal, alpha-Methyldopa, Methyl-L-dopa, L-Methyl Dopa, Methyldopum, Aldomin, Dopegit, Metildopa, (S)-(-)-alpha-Methyldopa, 3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE, L-(alpha-Md), 3-Hydroxy-alpha-methyl-L-tyrosine, alpha-Methyl-L-dopa, Bayer 1440 L, Apo-Methyldopa, L-alpha-Methyl DOPA, Nu-Medopa, alpha-Methyldopa (VAN), Dopergit, Novomedopa, alpha-Methyldihydroxyphenylalanine, alpha-Methyl-L-3,4-dihydroxyphenylalanine, L-alpha-Methyl-3,4-dihydroxyphenylalanine, L-Methyldopa, l-3-(3,4-Dihydroxyphenyl)-2-methylalanine, L-(-)-alpha-Methyldopa, Methyldopum [INN-Latin], Metildopa [INN-Spanish], Aldoril D30, Aldoril D50, Methyldopa (L,-), Methyldopa (anhydrous), levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine, AMD, L-(-)-|A-Methyldopa, L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine, Nr.C 2294, alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine, L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine, L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine, UNII-M4R0H12F6M, L-Tyrosine, 3-hydroxy-alpha-methyl-, MK 351, Methyldopa (INN), Methyldopa [INN], Aldomet (TN), Aldoril 15, Aldoril 25, L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid, (S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid, CCRIS 4671, HSDB 218, (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid, CHEBI:61058, EINECS 209-089-2, Methyldopa (Levorotatory), NSC 169916, Mk. b51, 41372-08-1, MLS000028644, M4R0H12F6M, CJCSPKMFHVPWAR-JTQLQIEISA-N, 3-Hydroxy-.alpha.-methyl-L-tyrosine, MK-351, 88620-56-8, Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-(-)-, NCI-C55721, SMR000059170, (-)-3-(3,4-Dihydroxyphenyl)-2-Methyl-L-Alanine Sesqui-Hydrate, Aldomine, Lederdopa, Q-201392, W-105555, METHYL DOPA (SEE ALSO METHYL DOPA SESQUIHYDRATE), SR-01000597712, aldochlor, Medoba, l-a-methyldopa, a-methyl dopa, NSC169916, a-methyl-l-dopa, 3,4-Dihydroxy-2-methylphenylalanine #, Anhydrous methyldopa, CAS-555-30-6, Prestwick_732, (-)-a-methyldopa, a-methyldopa (van), Aldoril (TN), Dopamet (TN), Dopegyt (TN), Methyldopa (Aldomet), Methyldopa 250 Tab, L-alpha-Methyl-DOPA, (-)-alpha-methyldopa, L-(-)--Methyldopa, L(-)-a-methylalanine, Spectrum_000937, Tocris-0584, MK-351; Methyldopa, Nu-Medopa Tab 125mg, Nu-Medopa Tab 250mg, Nu-Medopa Tab 500mg, L-(-)-?-Methyldopa, Novo-Medopa Tab 125mg, Novo-Medopa Tab 250mg, Novo-Medopa Tab 500mg, Prestwick0_000326, Prestwick1_000326, Prestwick2_000326, Prestwick3_000326, Spectrum2_001068, Spectrum3_000501, Spectrum4_000054, Spectrum5_001295, (s)-(-)-a-methyldopa, L(-)-alpha-methylalanine, DSSTox_CID_3295, CHEMBL459, D0BA6T, Epitope ID:146097, AC1Q29EL, AC1Q29EM, Apo Methyldopa Tab 125mg, Apo Methyldopa Tab 250mg, Apo Methyldopa Tab 500mg, DSSTox_RID_76962, DSSTox_GSID_23295, L-(a-MD), Lopac0_000853, SCHEMBL34003, BSPBio_000331, BSPBio_002021, KBioGR_000547, KBioSS_001417, cid_38853, MLS006011978, BIDD:GT0620, DivK1c_000142, Methyldopa 125 Tab 125mg, Methyldopa 500 Tab 500mg, SPECTRUM1500403, SPBio_001056, SPBio_002252, alpha-Methyl-dopa sesquihydrate, AC1L20K1, Aldoril;Dopamet;Dopegyt;Aldomet, BPBio1_000365, GTPL5217, DTXSID5023295, BDBM48449, CTK8B3998, HMS500H04, KBio1_000142, KBio2_001417, KBio2_003985, KBio2_006553, KBio3_001521, ZINC20255, MolPort-001-792-485, NINDS_000142, HMS1569A13, HMS1920N09, HMS2090B11, HMS2091F04, HMS2096A13, HMS2235N11, HMS3262L07, HMS3372J14, HMS3713A13, Pharmakon1600-01500403, L-(-)-a-methyl-a-methyl-Aldomin, HY-B0225, KS-00000VK2, Tox21_202610, Tox21_500853, ANW-43632, BG0252, CCG-40120, CM0081, DL-443, LS-216, NSC760080, s1642, Tyrosine, 3-hydroxy-.alpha.-methyl-, a-Methyl-L-3,4-dihydroxyphenylalanine, AKOS015960582, Aldoril, Dopamet, Dopegyt, Methyldopa, AC-8431, API0003115, CS-2172, DB00968, KS-1424, LP00853, MCULE-8885874119, NSC-760080, IDI1_000142, NCGC00024667-01, NCGC00024667-02, NCGC00024667-03, NCGC00024667-05, NCGC00024667-06, NCGC00024667-07, NCGC00024667-08, NCGC00024667-09, NCGC00024667-10, NCGC00024667-11, NCGC00024667-13, NCGC00260158-01, NCGC00261538-01, AC-11671, AJ-08427, AK114179, AS-13052, CC-30888, L-(-)-alpha-methyl-alpha-methyl-Aldomin, SC-21959, L-a-Methyl-(3, 4-dihydroxyphenyl)alanine, AB2000187, AX8021439, KB-211091, TR-019573, (-)-alpha-Methyl-3,4-dihydroxyphenylalanine, D1817, EU-0100853, FT-0603468, LT00847269, 3-(3,4-Dihydroxyphenyl)-?-methyl-L-alanine, L-alpha-Methyl-(3, 4-dihydroxyphenyl)alanine, C07194, D08205, AB00052043_09, AB01275508-01, AB01275508_02, C-10983, L-(-)-3-(3,4-dihydroxyphenyl)-2-methyl-Alanine, SR-01000597712-1, SR-01000597712-3, 3,4-dihydroxy-2-methylphenylalanine (ACD/Name 4.0), Z1565440340, 3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate, Methyldopa, European Pharmacopoeia (EP) Reference Standard, UNII-33TD13T99R component CJCSPKMFHVPWAR-JTQLQIEISA-N, (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid, Methyldopa, United States Pharmacopeia (USP) Reference Standard, Methyldopa for system suitability, European Pharmacopoeia (EP) Reference Standard, 133161-54-3, 1339-75-9, 4290-08-8, 779-08-8, L-(-)-AfAE'A centa' notA inverted exclamation markAfasA'A|AfAE'Adaggeratrade mark?-Methyldopa, AC1OCGED, ZB000781, (2S)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-2-methylpropanoate

ID: 341

InChIKey: CJCSPKMFHVPWAR-UHFFFAOYSA-N
SMILES: CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4138
synonyms found at PubChem are:
3-Hydroxy-alpha-methyl-DL-tyrosine, 55-40-3, Metholes, Mulfasin, DL-Methyldopa, DL-alpha-Methyl DOPA, 555-29-3, (-)-Methyldopa, 3-Hydroxy-alpha-methyltyrosine, racemic alpha-Methyldopa, (+-)-alpha-Methyldopa, 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid, .alpha.-Methyl dopa, L-.alpha.-Methyldopa, L-(.alpha.-Md), .alpha.-Methyl-L-dopa, .alpha.-Methyldopa, L-, EINECS 209-088-7, (+)-|A-methyldopa, L-Tyrosine, 3-hydroxy-.alpha.-methyl-, L-Methyldopa, (S)-(-)-.alpha.-Methyldopa, CJCSPKMFHVPWAR-UHFFFAOYSA-N, (+/-)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, 2-Methyl-3-(3,4-dihydroxyphenyl)alanine, .alpha.-Methyl-L-(3,4-dihydroxyphenyl)alanine, L-.alpha.-Methyl-(3,4-dihydroxyphenyl)alanine, Aldomine, Lederdopa, .alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)-L-alanine, ALANINE, 3-(3,4-DIHYDROXYPHENYL)-2-METHYL-, DL-, L-(-)-.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)alanine, NCI-C55721, SR-01000075631, 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid, Elanpres, Equibar, Methyl-dopa, NSC169916, 3-hydroxy-alpha, Methyldopa anhydrous, (+/-)-, .alpha.-Medopa, 3,4-Dihydroxy-2-methylphenylalanine #, Tyrosine, 3-hydroxy-alpha-methyl-, .alpha.-Methyldopa, EINECS 200-232-4, Methyldopa (Racemic), DL-alpha-Methyl-DOPA, L -alpha-Methyl-DOPA, AC1L1HHY, 3-(3,4-Dihydroxyphenyl)-2-methyl alanine, (-)-.alpha.-Methyldopa, CHEMBL718, AC1Q5S1Z, Lopac0_000770, SCHEMBL196981, Tyrosine, 3-hydroxy-a-methyl-, WLN: QVXZ1&1R CQ DQ, CTK5A3554, MolPort-001-497-431, HMS3259C21, HMS3262I22, HMS3266O08, ALBB-024010, BCP28393, Tox21_500770, CH0043, SBB000508, AKOS003273681, AKOS017258656, DL-Tyrosine, 3-hydroxy-alpha-methyl-, AC-8433, AN-8042, CCG-204855, LP00770, MCULE-3456177599, NC00520, NSC-169916, NCGC00015631-03, NCGC00015631-04, NCGC00015631-05, NCGC00094109-01, NCGC00094109-02, NCGC00261455-01, AC-11788, AN-23679, CPD001370753, LS-16067, SAM002554912, SC-11903, ST013867, SBI-0050748.P004, AB0012274, Alanine,4-dihydroxyphenyl)-2-methyl-, L-, alpha-methyl-3,4-dihydroxy-dl-phenylalanine, .alpha.-Methyl-L-3,4-dihydroxyphenylalanine, EU-0100770, FT-0604487, FT-0671718, R1917, DL-Tyrosine, 3-hydroxy-alpha-methyl- (9CI), 2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, M 7277, Alanine,4-dihydroxyphenyl)-2-methyl-, L-(-)-, 555H293, A830691, L001029, SR-01000076007, (?)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, (y)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-, alpha-METHYL-L-beta-3,4-DIHYDROXYPHENYLALANINE, I01-1041, SR-01000075631-1, SR-01000075631-3, SR-01000076007-1, W-105556, I14-13368, 2-amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid, L(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine, L-(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine, 2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYL-PROPANOIC, 2-azanyl-3-[3,4-bis(oxidanyl)phenyl]-2-methyl-propanoic acid, ( inverted question mark)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine, 2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-2- METHYL-PROPIONIC ACID(CATECHOL METABOLITE), A830692, 2-ammonio-3-(3,4-dihydroxyphenyl)-2-methylpropanoate, 2-azaniumyl-3-[3,4-bis(oxidanyl)phenyl]-2-methyl-propanoate

ID: 342

InChIKey: CJDRUOGAGYHKKD-RQBLFBSQSA-N
SMILES: CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H]([C@H]2[C@H]5O)N3[C@@H]1O)C6=CC=CC=C6N4C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6100671
synonyms found at PubChem are:
Ajmaline, Cardiorythmine, Ajmalin, Gilurytmal, Raugalline, Tachmalin, (+)-Ajmaline, Aritmina, Rauwolfine, Ignazin, Merabitol, Rauwolfin, Rhytmaton, Rytmalin, Siddiqui, Takycor, Ritmos, Ajmaline Hydrochloride, 4360-12-7, UNII-1PON08459R, 1PON08459R, Cartagine, Tajmalin, Takhmalin, NSC 15627, Rauverid, Ajmaline [JAN], Ajmalan-17,21-diol, ajmaline HCl, EINECS 224-439-4, NSC 628054, (17R,21alpha)-Ajmalan-17,21-diol, (17R,21-alpha)-Ajmalan-17,21-diol, AI3-62668, Ajmalan-17,21-diol, (17R,21alpha)-, compound with methanol (1:1), ZINC898188, Ajmalan-17,21-diol, (17R,21-alpha)- (9CI)

ID: 343

InChIKey: CJFQIVAOBBTJCI-UHFFFAOYSA-N
SMILES: COC1=C(C(=C(C=C1)C(=O)O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 79737
synonyms found at PubChem are:
2-Hydroxy-3,4-dimethoxybenzoic acid, 5653-46-3, 3,4-Dimethoxysalicylic acid, 3,4-dimethoxy-2-hydroxybenzoic acid, Benzoic acid, 2-hydroxy-3,4-dimethoxy-, CJFQIVAOBBTJCI-UHFFFAOYSA-N, VERATRIC ACID, 2-HYDROXY-, 2-Hydroxy-3,4-dimethoxybenzoicacid, 2-hydroxy-3,4-dimethoxybenzoes, EINECS 227-096-9, Spectrum_001290, AC1Q5TIF, Spectrum2_001921, Spectrum3_001124, Spectrum4_001968, Spectrum5_000841, AC1L2Y1C, BSPBio_002587, KBioGR_002440, KBioSS_001770, SCHEMBL419244, SPECTRUM1400164, SPBio_001921, CHEMBL1487905, CTK5A5300, KBio2_001770, KBio2_004338, KBio2_006906, KBio3_002087, DTXSID50205088, MolPort-000-882-126, ALBB-025280, NSC37414, ZINC1670010, ZX-AN023794, 8270AB, CCG-38488, FCH830640, NSC-37414, SBB072468, AKOS000278042, DS-6113, MCULE-6566886673, Benzoic acid,2-hydroxy-3,4-dimethoxy-, NCGC00095870-01, NCGC00095870-02, AJ-29147, KB-24376, AB0161964, AX8075535, CS-0036288, FT-0691703, R1325, ST45028286, A23076, 2-hydroxy-3,4-dimethoxybenzoic acid, AldrichCPR, C-52782, SR-05000002439, I01-7997, SR-05000002439-1

ID: 344

InChIKey: CJFTUKFVMMYYHH-UHFFFAOYSA-N
SMILES: C1(=C(C(=O)C(=C(C1=O)O)O)O)O.O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6420048
synonyms found at PubChem are:
123334-16-7, 2,3,5,6-tetrahydroxycyclohexa-2,5-diene-1,4-dione hydrate, Tetrahydroxy-1,4-benzoquinone Hydrate, Tetrahydroxy-1,4-quinone hydrate, Tetrahydroxy-1,4-quinone monohydrate, 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrahydroxy-, hydrate, CAS-319-89-1, SR-05000002066, THQ hydrate, Prestwick_964, ACMC-209aoq, AC1O4WIK, SCHEMBL565084, C6H6O7, tetrahydroxy-1,4quinone hydrate, CHEMBL1559303, CTK8A9535, MolPort-003-959-680, HMS1570H11, HMS2097H11, KS-000013CJ, ANW-18120, Tetrahydroxy-1,4-benzoquinoneHydrate, AKOS015855341, CCG-220835, RTC-066603, NCGC00017023-01, Tetrahydroxy-1,4-quinone hydrate, 99%, KB-81069, AX8153516, FT-0659816, ST24027262, Y2061, A821088, SR-05000002066-2, 2,3,5,6-tetrakis(oxidanyl)cyclohexa-2,5-diene-1,4-dione hydrate

ID: 345

InChIKey: CJJOSEISRRTUQB-UHFFFAOYSA-N
SMILES: COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2N=N1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2268
synonyms found at PubChem are:
Azinphos-methyl, Azinphosmethyl, azinphos methyl, Guthion, 86-50-0, Azinphos, Methylazinphos, Methylgusathion, Metiltriazotion, Crysthyon, Carfene, Cotneon, Cotnion, Cotnion methyl, Gusathion M, Gusathion Methyl, Crysthion 2L, Gusathion 25, Gusathion-20, Metazintox, Azinphos-metile, METHYL GUTHION, Azinfos-Methyl, Bayer 9027, Bayer 17147, Caswell No. 374, Gothnion, Azinfos-methyl [Dutch], Azinophos-methyl, Methyl gusathion, Azinphos-metile [Italian], NCI-C00066, BAY 9027, CCRIS 63, Azinphos-methyl [BSI:ISO], BAY 17147, ENT 23,233, EPA Shaughnessy #058001, UNII-265842EWUV, HSDB 1171, O,O-Dimethyl S-(3,4-dihydro-4-keto-1,2,3-benzotriazinyl-3-methyl) dithiophosphate, EINECS 201-676-1, Phosphorodithioic acid, O,O-dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester, R 1582, Benzotriazinedithiophosphoric acid dimethoxy ester, Phosphorodithioic acid, O,O-dimethyl ester, S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one, EPA Pesticide Chemical Code 058001, O,O-Dimethyl-S-(benzaziminomethyl) dithiophosphate, BRN 0280476, Dimethyldithiophosphoric acid N-methylbenzazimide ester, N-Methylbenzazimide, dimethyldithiophosphoric acid ester, AI3-23233, CHEBI:2953, O,O-Dimethyl S-(4-oxobenzotriazino-3-methyl)phosphorodithioate, 265842EWUV, O,O-Dimethyl S-(4-oxo-1,2,3-benzotriazino(3)-methyl) thiothionophosphate, O,O-Dimethyl S-(4-oxo-3H-1,2,3-benzotriazine-3-methyl)phosphorodithioate, O,O-Dimethyl-S-(1,2,3-benzotriazinyl-4-keto)methyl phosphorodithioate, Benzotriazine derivative of a methyl dithiophosphate, o,o-Dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] dithiophosphate, O,O-Dimethyl S-4-oxo-1,2,3-benzotriazin-3(4H)-ylmethyl phosphorodithioate, 1,2,3-Benzotriazin-4(3H)-one, 3-(mercaptomethyl)-, O,O-dimethyl phosphorodithioate, 3-(Mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one O,O-dimethyl phosphorodithioate S-ester, Phosphorodithioic acid, O,O-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] ester, O,O-Dimethyl-S-(4-oxobenzotriazin-3-methyl)-dithiophosphat, 3-(dimethoxyphosphinothioylsulfanylmethyl)-1,2,3-benzotriazin-4-one, 3-Dimethoxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one, DSSTox_CID_122, O,O-Dimethyl-S-(4-oxobenzotriazin-3-methyl)-dithiophosphat [German], O,O-Dimethyl S-(4-oxo-1,2,3-benzotriazino(3)-methyl)thiothionophosphate, O,O-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate, O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiofosfaat, O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiophosphat, O,O-Dimetil-S-((4-oxo-3H-1,2,3-benzotriazin-3-il)-metil)-ditiofosfato, DSSTox_RID_75384, O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiofosfaat [Dutch], O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiophosphat [German], O,O-Dimetil-S-((4-oxo-3H-1,2,3-benzotriazin-3-il)-metil)-ditiofosfato [Italian], S-(3,4-Dihydro-4-oxo-benzo(alpha)(1,2,3)triazin-3-ylmethyl) O,O-dimethyl phosphorodithioate, S-3,4-Dihydro-4-oxobenzo(d)(1,2,3)triazin-3-ylmethyl O,O-dimethyl phosphorodithioate, DSSTox_GSID_20122, Azimil, methyl azinphos, 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one, O,O-dimethyl phosphorodithioate, CAS-86-50-0, S-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-dimethyl phosphorodithioate, azinphosmethyn, Methyltriazotin, Azinugec, Gution, Cotnion-methyl, go thnion, Beetle Buster, Azinphos-Me, Bay Laurel, Gusthion M, C10H12N3O3PS2, Guthion®, Crysthyon 2L, Guthion, Gusation, Guthion(R), Ketokil No. 52, Spectrum_001769, SpecPlus_000352, AC1L1DAU, Spectrum2_001846, Spectrum3_000806, Spectrum4_000646, Spectrum5_001925, SCHEMBL27791, BSPBio_002271, KBioGR_000991, KBioSS_002250, SPECTRUM330013, MLS002695975, DivK1c_006448, SPBio_001632, CHEMBL530115, DTXSID3020122, CJJOSEISRRTUQB-UHFFFAOYSA-, KBio1_001392, KBio2_002249, KBio2_004817, KBio2_007385, KBio3_001771, GUTHION (AZINPHOS-METHYL), CJJOSEISRRTUQB-UHFFFAOYSA-N, HMS3089C06, Tox21_201965, Tox21_300929, CCG-39384, AKOS015902796, API0010017, LS-1854, Phosphorodithioic acid O,O-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] ester, NCGC00091883-01, NCGC00091883-02, NCGC00091883-03, NCGC00091883-04, NCGC00091883-05, NCGC00091883-06, NCGC00091883-07, NCGC00091883-08, NCGC00178729-01, NCGC00254831-01, NCGC00259514-01, BC655156, CC-24227, O,O-Dimethyl phosphorodithioate S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one (8CI), SMR000777867, ZB015212, Azinphos-methyl 10 microg/mL in Cyclohexane, FT-0602894, Azinphos-methyl 100 microg/mL in Cyclohexane, Azinphos-methyl 100 ng/microl in Acetonitrile, C11018, C-19518, O,O-dimethyl S-(benzaziminomethyl) dithiophosphate, Azinphos-methyl, PESTANAL(R), analytical standard, O,O-dimethyl S-(be nzaziminomethyl) dithiophosphate, BRD-K21893543-001-02-8, I14-19912, dimethyl dithiophosphoric acid N-methylbenzazimidyl ester, N-methylbenzazimide, dimethyl dithiophosphoric acid ester, O,O-dimethyl S-(4-oxobenzotriazino-3-methyl) phosphorodithioate, Dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate, O,O-dimethyl (4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl dithiophosphate, O,O-dimethyl S-(1,2,3-benzotriazinyl-4-keto)methyl phosphorodithioate, O,O-dimethyl S-(4-oxo-1,2,3-benz otriazino(3)-methyl) thiothionophosphate, O,O-dimethyl S-(4-oxo-3H-1,2,3-benzotriazine-3-methyl) phosphorodithioate, 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one O,O-dimethyl phosphorodithioate, 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one O,O-dimethyl phosphorodithioate S-est er, Dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) pho sphorodithioate, Dimethyl S-(3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one) phosphorodithioate, O,O-Dimethyl S-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl-methyl) dithiophosphate, O,O-dimethyl S-(4-oxobenzo[d][1,2,3]triazin-3(4H)-yl)methyl phosphorodithioate, O,O-Dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] dithiophosphate #, S-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-dimethyl phosphorodithio ate, S-(3,4-Dihydro-4-oxobenzo[d]-[1,2,3]-triazin-3-ylmethyl)OO-dimethyl-phosphorodithioate, S-(3,4-dihydro-4-oxobenzo[d][1,2,3]triazin-3-ylmethyl) O,O-dimethyl phosphorodithioate, 54182-73-9, Dimethoxy ester of (4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl ester of dithiophosphoric acid, InChI=1/C10H12N3O3PS2/c1-15-17(18,16-2)19-7-13-10(14)8-5-3-4-6-9(8)11-12-13/h3-6H,7H2,1-2H3, O,O-Dimethyl phosphorodithioate S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one, phosphorodithioic acid O,O-dimethyl ester, S-ester with 3-mercaptomethyl-1,2,3-b enzotriazin-4(3H)-one, phosphorodithioic acid O,O-dimethyl ester, S-ester with 3-mercaptomethyl-1,2,3-benzotriazin-4(3H)-one

ID: 346

InChIKey: CJNZAXGUTKBIHP-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)C(=O)O)I

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 6941
synonyms found at PubChem are:
2-IODOBENZOIC ACID, 88-67-5, o-Iodobenzoic acid, Benzoic acid, 2-iodo-, Iodobenzoic acid, Benzoic acid, o-iodo-, USAF EK-572, 2-iodo benzoic acid, 2-Iodo-benzoic acid, Benzoic acid, iodo-, Kyselina o-jodbenzoova, o-Jod-benzoesaeure, 2-Jod-benzoesaeure, C7H5IO2, UNII-7Q00V80J7Q, Kyselina o-jodbenzoova [Czech], NSC 3772, EINECS 201-850-7, BRN 1861406, AI3-01811, CHEBI:287979, CJNZAXGUTKBIHP-UHFFFAOYSA-N, 7Q00V80J7Q, 2-(Iodo-(125)I)-benzoic acid, sodium 2-iodobenzoate, 1321-07-9, Progonasyl, OISB, PubChem3924, Ortho-iodobenzoic acid, Benzoic acid, 2-iodo, ortho-iodo benzoic acid, ACMC-209qwc, Maybridge1_001326, WLN: QVR BI, ortho-iodo-sodium benzoate, IODOBENZOIC-2 ACID, AC1L1NN4, AC1Q72CC, 2-Iodobenzoic acid, 98%, SCHEMBL40612, o-iodobenzoic-(125)I acid, KSC180E7D, 2-iodobenzoic-(125)I acid, AC1Q5U94, CHEMBL112424, RARECHEM AL BO 0686, DTXSID6058976, 88-67-5 2-Iodobenzoic acid, CTK0I0271, HMS545E06, ZINC90931, NSC3772, ATTERCOP-CHM AT113663, MolPort-000-141-681, 2-Iodobenzoic acid, 98% 25g, ACT12259, CS-D0909, KS-000000XT, NSC-3772, STR04823, AN-912, ANW-39130, BBL009655, MFCD00002419, SBB063117, STK256890, WT1376, AKOS000119657, ACN-000247, AS02216, BS-4598, CCG-233561, CM12818, EBD1988491, LS00003, MCULE-5987010449, RP06056, RTR-027898, TRA0020257, 2532-17-4 (mono-hydrochloride salt), AC-26054, AJ-10853, BR-73132, KB-24664, LS-37717, SC-07181, SRI-10864-03, TL806108, AB0007670, AB1003975, DB-014123, ST2410059, TR-027898, AM20041295, FT-0612665, FT-0659004, I0053, ST45061707, 2-Iodobenzoic acid, purum, >=95.0% (GC), A15882, A20364, M-6055, AA-506/30136037, I01-0407, I01-5544, W-100392, 2-Iodobenzoic acid, >=99%, purified by sublimation, F0001-2188, InChI=1/C7H5IO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10

ID: 347

InChIKey: CJUOSBUQOWKEKJ-UHFFFAOYSA-N
SMILES: CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=CC=C4.CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=CC=C4.C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 22529
synonyms found at PubChem are:
Mebhydrolin napadisylate, 6153-33-9, Diazoline, Mebhydrolin napadisilate, Diazolin, Incidal, Omeril, Mebhydroline Napadisylate, Diazolinum, Mebhydrolin (napadisylate), Mebhydroline 1,5-naphthalenedisulfonate salt, UNII-O5G04RB25M, EINECS 228-170-3, O5G04RB25M, Mebhydrolin 1,5-naphtalenedisulfonate, Mebhydroline 1,5-naphtalenedisulfonate, NCGC00017059-01, CAS-6153-33-9, 1,5-Naphthalenedisulfonic acid, compd. with 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)-1H-pyrido(4,3-b)indole (1:2), 1,5-Naphthalenedisulfonic acid, compd. with 2,3,4,5-tetrahydro-5-benzyl-2-methyl-1H-pyrido(4,3-b)indol (1:2), diazo-line, Mebhydrolin napadisylate [JAN], 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole;naphthalene-1,5-disulfonic acid, Prestwick_605, AC1L2KJT, DSSTox_CID_25566, DSSTox_RID_80963, DSSTox_GSID_45566, SCHEMBL541584, Mebhydrolin napadisilate (JAN), CHEMBL1324326, DTXSID3045566, CHEBI:31803, C48H48N4O6S2, MolPort-005-940-376, HMS1569K12, HMS2096K12, HMS3713K12, HY-B1303, Tox21_110763, AKOS015896405, CCG-220455, CS-4851, MCULE-1153020693, 2C19H20N2.C10H8O6S2, AC-22580, AS-13277, H782, LS-94672, SC-77504, FT-0650724, C13254, D01786, 153M339, A833282, C-55227, I06-2002, 9-Benzyl-N-methyl-1,2,3,4-tetrahydro-|A-carboline, Mebhydroline 1,5-naphthalenedisulfonate salt, analytical standard, 2-methyl-5-(phenylmethyl)-3,4-dihydro-1H-pyrido[4,3-b]indole; naphthalene-1,5-disulfonic acid, 5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole heminaphthalene-1,5-disulfonate

ID: 348

InChIKey: CJXMVKYNVIGQBS-OWOJBTEDSA-N
SMILES: C1=CC(=CC=C1/C=C/C=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 641301
synonyms found at PubChem are:
3-(4-hydroxyphenyl)acrylaldehyde, 2538-87-6, p-Coumaraldehyde, p-Hydroxycinnamaldehyde, 4-hydroxycinnamaldehyde, 4-Hydroxycinnamyl aldehyde, (E)-3-(4-Hydroxyphenyl)acrylaldehyde, COUMARALDEHYDE, (E)-3-(4-hydroxyphenyl)-2-propenal, (E)-3-(4-hydroxyphenyl)prop-2-enal, (2E)-3-(4-hydroxyphenyl)acrylaldehyde, trans-p-Hydroxycinnamaldehyde, (2E)-3-(4-hydroxyphenyl)prop-2-enal, 20711-53-9, CHEBI:28353, 3-(4-hydroxyphenyl)prop-2-enal, 2-propenal, 3-(4-hydroxyphenyl)-, (2E)-, 4-coumaraldehyde, p-coumaryl aldehyde, (E)-4-coumaraldehyde, 4-hydroxy cinnamaldehyde, bmse000611, bmse010084, AC1LD2K1, trans-4-hydroxycinnamaldehyde, SPECTRUM231070, SCHEMBL196960, SCHEMBL197453, CHEMBL431836, 3-(4-Hydroxyphenyl)-2-propenal, MolPort-003-665-677, MolPort-027-631-768, ZINC1530240, CCG-39470, AKOS006271961, RL02846, NCGC00095729-01, AJ-26644, AS-50095, KB-27117, 4CH-005297, ST24041479, C05608, A817838, J-510715, InChI=1/C9H8O2/c10-7-1-2-8-3-5-9(11)6-4-8/h1-7,11H/b2-1

ID: 349

InChIKey: CJZVOKPFTJGMCD-UHFFFAOYSA-N
SMILES: C#CCCC1=NN(C(=O)C1)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 11127580
synonyms found at PubChem are:
1-Phenyl-3-(3-butynyl)-2-pyrazoline-5-one, 3-(but-3-yn-1-yl)-1-phenyl-1h-pyrazol-5(4h)-one, 1027200-36-7

ID: 350

InChIKey: CKAKVKWRMCAYJD-UHFFFAOYSA-N
SMILES: CCC1=CC(=CC=C1)N(C)C(=NC2=CC=CC3=CC=CC=C32)N.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 60839
synonyms found at PubChem are:
Cerestat, Aptiganel HCl, APTIGANEL HYDROCHLORIDE, CNS-1102, UNII-40PWH14OXW, Cns 1102, 137160-11-3, 40PWH14OXW, NCGC00093759-01, DSSTox_CID_25762, DSSTox_RID_81104, DSSTox_GSID_45762, CHEMBL554054, N-(1-Naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine hcl, SMR000326976, CAS-137160-11-3, AC1Q3CFJ, D01HTH, MLS000862213, MLS001056791, SCHEMBL871689, AC1L1U12, DTXSID9045762, CKAKVKWRMCAYJD-UHFFFAOYSA-N, MolPort-003-940-636, Tox21_111220, Tox21_500312, AKOS025293480, Tox21_111220_1, CCG-221616, LP00312, NCGC00015236-04, NCGC00260997-01, CNS-1102, >98% (HPLC), solid, EU-0100312, SR-01000075235, SR-01000075235-1, 1-(3-ethylphenyl)-1-methyl-2-naphthalen-1-ylguanidine hydrochloride, N-(1-naphthyl)-N'-(m-ethylphenyl)-N'-methyl-guanidine hydrochloride, N-(1-naphthyl)-N'-(m-ethylphenyl)-N'-methylguanidine hydrochloride, N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride, 1-(3-ethylphenyl)-1-methyl-3-(1-naphthyl)guanidine hydrochloride(1:1), 1-(m-Ethylphenyl)-1-methyl-3-(1-naphthyl)guanidine monohydrochloride, Guanidine, N-(3-ethylphenyl)-N-methyl-N'-1-naphthalenyl, monohydrochloride, Guanidine, N-(3-ethylphenyl)-N-methyl-N'-1-naphthalenyl-, monohydrochloride, N-(3-Ethylphenyl)-N-methyl-N inverted exclamation mark -1-naphthalenylguanidine hydrochloride, N-(3-Ethylphenyl)-N-methyl-N inverted question mark-1-naphthalenylguanidine monohydrochloride; Cerestat; Aptiganel hydrochloride

ID: 351

InChIKey: CKLJMWTZIZZHCS-REOHCLBHSA-N
SMILES: C([C@@H](C(=O)O)N)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5960
synonyms found at PubChem are:
L-aspartic acid, aspartic acid, 56-84-8, H-Asp-OH, L-aspartate, Asparagic acid, Aspatofort, L-Asparagic acid, L-Aminosuccinic acid, (S)-2-Aminosuccinic acid, Asparaginic acid, L-Asparaginic acid, (2S)-2-aminobutanedioic acid, (S)-Aspartic acid, (2S)-Aspartic acid, aspartate, (S)-Aminobutanedioic acid, L-Aspartinsaeure, L-Asparaginsaeure, L-Asparaginsyra, Aspartic acid, L-, Acidum asparticum, L-(+)-Aspartic acid, L-Asp, L-2-Aminobutanedioic acid, Aspartate, L-, Asparaginsaeure [German], Aminosuccinic acid, Butanedioic acid, amino-, (S)-, Aspartic acid (VAN), Asparagic acid (VAN), Asparaginic acid (VAN), Acide aspartique [INN-French], Acido aspartico [INN-Spanish], (L)-ASPARTIC ACID, (+)-Aspartic acid, (S)-(+)-Aminosuccinic acid, FEMA No. 3565, CCRIS 6181, Acidum asparticum [INN-Latin], HSDB 1430, L( )-Aminobernsteinsaeure, AI3-04461, NSC 3973, Aspartic Acid [USAN:INN], BRN 1723530, l(+)-aspartic acid, Calcium diaspartate, EINECS 200-291-6, 25608-40-6, (S)-(+)-Aspartic acid, (S)-2-aminobutanedioic acid, CHEMBL274323, 6899-03-2, asp, CHEBI:17053, UNII-Z4FZM6CA61, CKLJMWTZIZZHCS-REOHCLBHSA-N, Calcium dihydrogen di-L-aspartate, (S)-Aspartate, (+)-Aspartate, [3H]-L-aspartate, L-Aspartic acid-13C4, 1-Amino-1,2-carboxyethane, (S)-Aminobutanedioate, [3H]L-aspartic acid, [3H]-L-aspartic acid, Asparaginsaeure, Polysuccinimide, (2S)-2-azanylbutanedioic acid, Acido aspartico, Z4FZM6CA61, Acide aspartique, 39162-75-9, 56-84-8 (Parent), Polyaspartic acid, Poly-DL-succinimide, 55443-54-4, 4-04-00-02998 (Beilstein Handbook Reference), L(+)-Aminobernsteinsaeure, L-Aspartic acid homopolymer, Aminosuccinate, Asparagate, Asparatate, L-Aspartic acid, homopolymer, L-Asparagate, L-Aminosuccinate, Aspartic acid [USAN:USP:INN], (L)-Aspartate, L- Aspartic acid, alpha-Aminosuccinate, (2S)-Aspartate, EINECS 254-327-0, L-(+)-Aspartate, L-[14C]aspartate, Beta-L-Aspartic Acid, L-Aspartic acid, 2, (R)-2-aminosuccinate, (S)-2-aminosuccinate, Tocris-0214, [3h]-l-asp, (S)-amino-Butanedioate, alpha-Aminosuccinic acid, (S)-Aminosuccinic Acid, (S)-(+)-Aspartate, L-Aspartic acid (9CI), 2-Amino-3-methylsuccinate, Biomol-NT_000168, bmse000031, bmse000875, D0OT9B, Aspartic acid (USP/INN), EC 200-291-6, AC1L1LI6, L-Aspartic acid (JP17), SCHEMBL3231, (S)-amino-Butanedioic acid, L-Aspartic acid, >=98%, L-Aspartic acid, 99.0%, Lopac0_000133, Aspartic acid, L- (8CI), KSC269K5J, DL-Aspartic acid, homopolymer, AC1Q4U77, BPBio1_001128, GTPL3309, GTPL4534, DTXSID7022621, aspartic acid (L-aspartic acid), BDBM18125, CTK1G9554, L-Aspartic acid, >=98%, FG, MolPort-001-792-017, HMS3260K08, ZINC895032, .alpha.-Aminosuccinic acid, (L)-, 21059-46-1 (calcium salt), 14007-45-5 (potassium salt), Tox21_500133, 2001-89-0 (di-potassium salt), ANW-32591, MFCD00002616, PDSP1_000819, PDSP2_000806, 1115-63-5 (mono-potassium salt), 17090-93-6 (hydrochloride salt), AKOS006239578, AKOS015853957, 5598-53-8 (di-hydrochloride salt), AM81585, CCG-204228, DB00128, LP00133, LS-2569, MCULE-6700641640, RP16381, RP20039, RTC-066533, 3792-50-5 (mono-hydrochloride salt), NCGC00024499-01, NCGC00024499-02, NCGC00024499-03, NCGC00024499-04, NCGC00024499-05, NCGC00024499-06, NCGC00260818-01, 27881-03-4, AJ-24135, AN-23565, BP-13291, KB-53137, SC-05405, SC-91380, TL806193, L-Aspartic acid, Vetec(TM) reagent grade, 2068-80-6 (magnesium (2:1) salt), AB1002629, DB-029944, KB-211185, ST2414603, TC-066533, 39162-75-9 (calcium (2:1) salt), A0546, EU-0100133, FT-0627708, FT-0655880, FT-0693446, L-Aspartic acid, BioXtra, >=99% (HPLC), V1940, L-Aspartic acid, BioUltra, >=99.5% (T), A 9256, C-4546, C00049, D00013, M03000, L-Aspartic acid, SAJ special grade, >=99.0%, A817928, A824434, L-Aspartic acid, reagent grade, >=98% (HPLC), SR-01000597734, I04-1073, I04-1122, I14-2732, SR-01000597734-3, (S)-(+)-Aminosuccinic acid; (S)-Aminobutanedioic acid, F8889-8684, Z1270403519, A4B5FB11-A4B6-4D75-9860-2ACF670700B9, UNII-28XF4669EP component CKLJMWTZIZZHCS-REOHCLBHSA-N, UNII-30KYC7MIAI component CKLJMWTZIZZHCS-REOHCLBHSA-N, Aspartic acid, European Pharmacopoeia (EP) Reference Standard, L-Aspartic acid, certified reference material, TraceCERT(R), Aspartic acid, United States Pharmacopeia (USP) Reference Standard, L-Aspartic acid, BioReagent, suitable for cell culture, suitable for insect cell culture, L-Aspartic acid, Pharmaceutical Secondary Standard; Certified Reference Material, 1236300-18-7, 155436-59-2, 155436-61-6, 155436-63-8, 155436-65-0, 181119-33-5, 181119-34-6, 221628-95-1, 26834-87-7, 90819-17-3, L-Aspartic acid, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%, L-Aspartic acid, PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture, D09BKX

ID: 352

InChIKey: CKSJXOVLXUMMFF-UHFFFAOYSA-N
SMILES: CCCCCCOC1=CC=CC=C1C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3316
synonyms found at PubChem are:
exalamide, 2-(Hexyloxy)benzamide, 53370-90-4, Hyperan, 2-n-Hexyloxybenzamide, o-Hexyloxybenzamide, 2-Hexyloxybenzamide, Exalamida, Exalamidum, 2-hexoxybenzamide, Benzamide, 2-(hexyloxy)-, o-(Hexyloxy)benzamide, Exalamide [INN:JAN], Exalamidum [INN-Latin], Exalamida [INN-Spanish], UNII-7JEC65JCG2, H.P. 216, EINECS 258-504-3, BRN 2645003, 7JEC65JCG2, BENZAMIDE, o-HEXYLOXY-, CHEBI:31585, CKSJXOVLXUMMFF-UHFFFAOYSA-N, NCGC00095049-01, DSSTox_CID_25899, DSSTox_RID_81211, DSSTox_GSID_45899, CAS-53370-90-4, ortho-hexyloxybenzamide, Spectrum_001729, Exalamide (JAN/INN), AC1L1FNN, Spectrum2_000869, Spectrum5_001095, KBioSS_002209, DivK1c_000140, SCHEMBL151112, SPECTRUM1503403, SPBio_000917, BEN685, CHEMBL1405973, DTXSID9045899, CTK8F9710, HMS500G22, KBio1_000140, KBio2_002209, KBio2_004777, KBio2_007345, NINDS_000140, HMS1922C12, Pharmakon1600-01503403, HY-B1224, ZINC1542919, Tox21 111403, Tox21_111403, CCG-39743, NSC758449, AKOS016014129, Tox21_111403_1, API0025897, CS-4872, NSC-758449, VA10874, IDI1_000140, NCGC00095049-02, NCGC00095049-04, AJ-26862, AN-40751, CJ-24332, LS-26914, SBI-0051822.P002, AX8002769, KB-224085, FT-0630660, D01585, AB00052353_02, 370E904, A829549, SR-01000872750, SR-01000872750-1, BRD-K12609457-001-02-3

ID: 353

InChIKey: CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES: C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5C(=O)C4=C3C)C)O)C)NC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10098
synonyms found at PubChem are:
JERVINE, 469-59-0, 11-Ketocyclopamine, Iervin, Jerwiny [Polish], UNII-19V3ECX465, HSDB 3502, NSC 7520, EINECS 207-417-9, BRN 0059109, CHEBI:6088, CHEMBL186779, C27H39NO3, 19V3ECX465, NSC23898, Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3beta,23beta)-, 17,23beta-Epoxy-3beta-hydroxyveratraman-11-one, Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10, 11B-tetramethyl-, NSC7520, Jerwiny, Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3-beta,23-beta)-, Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy- 3',6',10,11b-tetramethyl-, NSC-7520, Veratraman-11-one,23-epoxy-3-hydroxy-, (3.beta.,23.beta.)-, WLN: L D6 B566 CV FX DU LUTJ A1 E1 OQ F-& CT56 BOX FMTJ D1 H1, Spiro[9H-benzo[a]fluorene-9,2-b]-pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, AC1L1UHH, SCHEMBL61568, 4-27-00-03590 (Beilstein Handbook Reference), CLEXYFLHGFJONT-DNMILWOZSA-N, MolPort-003-873-278, (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-spiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one, HY-N0836, ZINC4098876, BDBM50170645, Jervine, >=98% (HPLC), powder, MFCD01684066, NSC-23898, s4747, AKOS025405251, CCG-208226, CS-3004, LS-145833, J0009, X0086, C10811, (3|A, 23|A)-17,23-Epoxy-3-hydroxyveratraman-11-one, (3beta,23beta)-17,23-Epoxy-3-hydroxyveratraman-11-one, UNII-4I27BB349X component CLEXYFLHGFJONT-DNMILWOZSA-N, UNII-QVO4N8484O component CLEXYFLHGFJONT-DNMILWOZSA-N, (3|A,23|A)- 17,23- Epoxy- 3-hydroxyveratraman- 11-one, Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3-beta,23-beta)- (9CI), Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3beta,23beta)- (9CI), (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one, 5''-hydroxy-2'',3,6,15''-tetramethyl-(1''S,2''R,2''R,3R,3aS,5''S,6S,7aR,10''S,11''S)-spiro[perhydrofuro[3,2-b]pyridine-2,14''-tetracyclo[8.7.0.02,7.011,16]heptadeca-7'',15''-diene]-17''-one

ID: 354

InChIKey: CLJHABUMMDMAFA-UHFFFAOYSA-N
SMILES: CC(CCC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 13320
synonyms found at PubChem are:
Tocodilydrin, Arlibide, Bufedon, Buphedrin, Dilydrin, Penitardon, Rolidrin, Rudilin, Tocodrin, Vasiten, Verina, Arlidin, Dilatol, Buphenin hydrochloride, Suprifen psb hydrochloride, Nylidrin HCl, EINECS 212-701-0, NSC 142004, 1-p-Hydroxyphenyl-2-(1'-methyl-3'-phenylpropylamino)-1-propanol hydrochloride, Benzenemethanol, 4-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-, hydrochloride, p-Hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)benzyl alcohol hydrochloride, Benzyl alcohol, p-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-, hydrochloride, Nylidrin hydrochloride [USP], AC1L21HX, C19H25NO2.HCl, 447-41-6 (Parent), AN-20539, LS-43047, [1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-(4-phenylbutan-2-yl)azanium chloride, [2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]-(1-methyl-3-phenyl-propyl)ammonium, [2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]-(1-methyl-3-phenyl-propyl)ammonium chloride, 3595-06-0, 900-01-6, 91408-84-3, AC1LCWGY, SCHEMBL15512520, AKOS026749811, hydron; 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol; chloride, Nylidrin hydrochloride, 849-55-8, Buphenine hydrochloride, Dilatyl, Arlidin hydrochloride, Dilatol hydrochloride, Nylidrin (hydrochloride), MLS000069387, SMR000058488, C19H26ClNO2, 4-(1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl)phenol hydrochloride, 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol hydrochloride, 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol;hydrochloride, SR-01000002981, Arlidin (TN), Nylidrine hydrochloride, AC1NWAPC, Nylidrin(hydrochloride), Opera_ID_1722, MLS001076116, Nylidrin hydrochloride (JAN), SCHEMBL364078, SPECTRUM1500445, CHEMBL1204337, CHEBI:31925, CTK8G2093, KS-00001FBU, MolPort-003-666-247, HMS1920D06, Pharmakon1600-01500445, HY-B1404, Tox21_500911, CCG-40183, NSC142004, NSC757252, WLN: QR DYQY1&MY1&2R &GH, AKOS030242878, API0010060, CS-4980, LP00911, MCULE-4564041662, NSC-142004, NSC-757252, NCGC00094222-01, NCGC00094222-02, NCGC00094222-03, NCGC00094222-04, NCGC00261596-01, AS-19644, EU-0100911, FT-0757340, N-153, Y2107, D01543, C-45962, SR-01000002981-2, 1-p-Hydroxyphenyl-2-[(1'-methyl-3'-phenylpropyl)amino]-1-propanol hydrochloride, p-Hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]benzyl alcohol hydrochloride

ID: 355

InChIKey: CMKFQVZJOWHHDV-NQZBTDCJSA-N
SMILES: CCC1=C[C@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5458190
synonyms found at PubChem are:
Catharanthine, 2468-21-5, UNII-WT0YJV846J, WT0YJV846J, CHEMBL2163793, (+)-Catharanthine, EINECS 219-586-6, Methyl (2alpha,5beta,6alpha)-3,4-didehydroibogamine-18beta-carboxylate, Catharanthine Base, Methyl (2-alpha,5-beta,6-alpha,18-beta)-3,4-didehydroibogamine-18-carboxylate, Catharanthine, >=95% (HPLC), CMKFQVZJOWHHDV-NQZBTDCJSA-N, MolPort-006-114-421, HMS2095F15, HMS3652A13, HMS3712F15, Ibogamine-18-carboxylic acid, 3,4-didehydro-, methyl ester, (2-alpha,5-beta,6-alpha,18-beta)-, BDBM50396009, s3202, ZINC57297068, AKOS024463388, CCG-220187, ST24046287, Q-9249, AB01566866_01, 468C215, Q-100319, (1beta,4beta)-2,6-[Ethylene(1H-indole-3,2-diyl)]-7-ethyl-2-azabicyclo[2.2.2]octa-7-ene-6beta-carboxylic acid methyl ester

ID: 356

InChIKey: CMWTZPSULFXXJA-VIFPVBQESA-N
SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 156391
synonyms found at PubChem are:
NAPROXEN, 22204-53-1, (S)-Naproxen, Naprosyn, Naproxene, (+)-Naproxen, Equiproxen, Aleve, Laraflex, Naproxeno, Naproxenum, d-Naproxen, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, (S)-(+)-Naproxen, Calosen, Naprosyne, Nycopren, Bonyl, Naixan, Reuxen, Axer, (+)-(S)-Naproxen, Ec-Naprosyn, (S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Acusprain, Anexopen, Arthrisil, Artrixen, Artroxen, Bipronyl, Clinosyn, Danaprox, Flexipen, Leniartil, Novonaprox, Anaprox, Apronax, Artagen, Atiflan, Congex, Daprox, Genoxen, Lefaine, Nafasol, Nalyxan, Napflam, Napmel, Naposin, Napren, Naprius, Fuxen, Naxen, Naxyn, Dysmenalgit N, Apo-Naproxen, (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Veradol, Xenar, Floginax, Headlon, Napratec, Naprontag, Narocin, Naxopren, Prafena, Priaxen, Pronaxen, Rheumaflex, Saritilron, Sinartrin, Soproxen, Sutolin, Tohexen, Traumox, Flexen, Napxen, Noflam, Patxen, Rahsen, Sinton, Sutony, Velsay, Vinsen, Methoxypropiocin, Narma, Roxen, Anax, (S)-2-(6-Methoxy-2-naphthyl)propionic acid, Flanax Forte, (+)-2-(6-Methoxy-2-naphthyl)propionic acid, Naprosyn LLE, Napren E, Proxen LE, Naxen F, Proxen LLE, U-Ritis, (+)-2-(Methoxy-2-naphthyl)-propionic acid, RS-3540, Naprelan, Naprosyn LLE Forte, Naproxi 250, Naproxi 500, (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, Naxyn 250, Naxyn 500, (S)-2-(6-Methoxy-2-naphthyl)propanoic acid, Equiproxen (Veterinary), Apo-Napro-NA, (S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, Naproxene [INN-French], Naproxenum [INN-Latin], Naproxeno [INN-Spanish], d-2-(6-Methoxy-2-naphthyl)propionic acid, (+)-2-(Methoxy-2-naphthyl)-propionsaeure, naproxen(+), UNII-57Y76R9ATQ, (+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, Dysmenalgit, Diocodal, Prexan, Proxen, CG 3117, CCRIS 5265, CHEBI:7476, HSDB 3369, EINECS 244-838-7, CHEMBL154, RS 3540, 57Y76R9ATQ, d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure, (2S)-2-(6-methoxy-2-naphthyl)propanoic acid, CMWTZPSULFXXJA-VIFPVBQESA-N, Naprium, Naprux, Laser, (+)-2-(Methoxy-2-naphthyl)-propionsaeure [German], (+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, Propionic acid, 2-(6-methoxy-2-naphthyl)-, (+)-, d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure [German], Duk, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (+)-, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (S)-, CAS-22204-53-1, Naprosine, Panoxen, Proxine, Mnpa, (S)-2-(6-Methoxy-naphthalen-2-yl)-propionic acid, 26159-31-9, (S)-6-Methoxy-.alpha.-methyl-2-naphthaleneacetic acid, DL Naproxen, Naprosin, Xenar-CR, aproxen, 2-Naphthaleneacetic acid, 6-methoxy-.alpha.-methyl-, (S)-, Naprolag, Naprosy, SR-01000075977, 2-Naphthaleneacetic acid, 6-methoxy-.alpha.-methyl-, (.alpha.S)-, Naproxen [USAN:BAN:INN:JAN], Naprosyn (TN), Naproxen,(S), NPS, Prestwick_349, Naproxen [USAN:USP:INN:BAN:JAN], PubChem8102, Spectrum_000977, 4or0, 4po0, (S)-(+)-Naproxene, Prestwick0_000791, Prestwick1_000791, Prestwick2_000791, Spectrum2_001043, Spectrum3_000514, Spectrum4_000069, Spectrum5_001327, (+)NAPROXEN, Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid, D0DJ1B, D0S2QI, Epitope ID:139974, UPCMLD-DP001, 2-(6-Methoxy-naphthalen-2-yl)-propionic acid(Naproxen), EC 244-838-7, AC1L4G3X, AC1Q4ET9, AC1Q4F4H, AC1Q4F4I, SCHEMBL3046, DSSTox_CID_20686, DSSTox_RID_79542, DSSTox_GSID_40686, Lopac0_000792, BSPBio_002067, KBioGR_000597, KBioSS_001457, KSC911E2L, ARONIS24306, BIDD:GT0062, DivK1c_000242, SPECTRUM1500425, Naproxen (JP17/USP/INN), SPBio_000966, SPBio_002861, GTPL5230, DTXSID4040686, UPCMLD-DP001:001, CMWTZPSULFXXJA-VIFPVBQESA-, CTK8B1225, HMS500M04, KBio1_000242, KBio2_001457, KBio2_004025, KBio2_006593, KBio3_001567, KS-00002WWU, Naproxen 1.0 mg/ml in Methanol, MolPort-000-145-960, NINDS_000242, HMS1920P13, HMS2089N21, HMS2091H12, HMS3649M13, Pharmakon1600-01500425, ZINC105216, ACT02593, Tox21_301953, ANW-24773, BDBM50339185, CCG-40130, MFCD00010500, NSC750183, NSC757239, AKOS005267223, AC-1363, CS-2163, DB00788, MCULE-2589082817, ME-0100, NSC-750183, NSC-757239, RP27889, RTR-010461, IDI1_000242, NCGC00016759-01, NCGC00016759-02, NCGC00016759-03, NCGC00021127-01, NCGC00161591-01, NCGC00255562-01, AJ-11169, AN-14988, BC208049, BR-72928, HY-15030, SC-02561, SY015060, (+)-2-(Methoxy-2-naphthyl)-propionsaure, Naproxen, meets USP testing specifications, SBI-0050769.P004, AB1009325, LS-124738, ST2408284, TL8003659, AM20060551, FT-0082415, FT-0602835, M1021, W4580, Naproxen, VETRANAL(TM), analytical standard, (S)-2-(6-methoxy-2-naphthyl)-propionic acid, 04N531, C01517, D00118, J10145, M-5280, (2S)-2-(6-methoxy(2-naphthyl))propanoic acid, AB00052049-04, AB00052049_05, (+)(S)2-(6-methoxy-2-naphthyl)-propionic acid, 2-(6-Methoxy-2-naphthyl)propanoic acid , (+)-, SR-01000003110, Q-201447, SR-01000003110-5, SR-01000075977-3, SR-01000075977-4, (+)-6-Methoxy-.alpha.-methyl-2-napthaleneacetic acid, BRD-K59197931-001-02-9, BRD-K59197931-001-03-7, BRD-K59197931-236-09-6, SR-01000075977-10, (+)-6-Methoxy-.alpha.-methyl-2-naphthaleneacetic acid, (alphas)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid, (S)-()-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, (S)-(+)-2-(6-methoxy-naphthalen-2-yl)-propionic acid, (S)-6-Methoxy-.alpha.-methyl-2-naphthalene acetic acid, Naproxen, British Pharmacopoeia (BP) Reference Standard, Naproxen, European Pharmacopoeia (EP) Reference Standard, (S)-(+)-6-Methoxy-alp.-methyl-2-naphthalene acetic acid, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid; Naproxen, (S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid, 98%, 2-Naphthaleneacetic acid, 6-methoxy-.alpha.-methyl-, (+)-, Naproxen, United States Pharmacopeia (USP) Reference Standard, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (+)- (8CI), Naproxen, Pharmaceutical Secondary Standard; Certified Reference Material, Naproxen solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, InChI=1/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1

ID: 357

InChIKey: CMXGHLJKXLIMAQ-UHFFFAOYSA-N
SMILES: CC(=C)C1CC2=C(O1)C=CC(=C2O)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3919910
synonyms found at PubChem are:
TUBAIC ACID, KBio2_004996, Spectrum_001902, SpecPlus_000730, AC1N0NMA, Spectrum2_001918, Spectrum3_001725, Spectrum4_001642, Spectrum5_000483, BSPBio_003370, KBioGR_002103, KBioSS_002434, DivK1c_006826, SPECTRUM1600587, SPBio_001916, SCHEMBL4279694, CHEMBL1479987, CHEBI:91480, KBio1_001770, KBio2_002428, KBio2_007564, KBio3_002590, CCG-38486, SDCCGMLS-0066842.P001, NCGC00095950-01, NCGC00095950-02, BRD-A02176148-001-02-2, 4-hydroxy-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-carboxylic acid

ID: 358

InChIKey: CNKBMTKICGGSCQ-ACRUOGEOSA-N
SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)NC(=O)[C@H](CCCCN)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6710772
synonyms found at PubChem are:
lysylphenylalanyltyrosine, H-LYS-PHE-TYR-OH, 63958-93-0, KBio3_002930, Spectrum2_001494, Spectrum3_001814, AC1O8K2J, BSPBio_003427, SPBio_001507, SCHEMBL4283579, CHEMBL3039098, CHEBI:92826, CTK1I5697, DTXSID30425121, ZINC9212671, CCG-39207, NCGC00178072-01, L-Tyrosine, N-(N-L-lysyl-L-phenylalanyl)-, BRD-K47328134-001-02-0, (2S)-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

ID: 359

InChIKey: CNLBARWYBMFQSI-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC(=CC=C3)F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 127032283
synonyms found at PubChem are:
CHEMBL3781738

ID: 360

InChIKey: CNNVSINJDJNHQK-UHFFFAOYSA-N
SMILES: CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 31872
synonyms found at PubChem are:
Leoplexamin, Pallopikeron, Lenipan, Sinalgico, Oxadol, Fenazoxine hydrochloride, EINECS 245-585-5, R 738, 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride, 1H-2,5-BENZOXAZOCINE, 5-METHYL-1-PHENYL-3,4,5,6-TETRAHYDRO-, HYDROCHLORIDE, AC1L1MI5, C17H19NO.HCl, LS-42051, 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-ium chloride, Nefopam hydrochloride, 23327-57-3, Nefopam HCl, 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride, Acupan, Nefopam (hydrochloride), Ajan, Nefopam hydrochloride [USAN], 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine hydrochloride, DSSTox_CID_25441, DSSTox_RID_80882, DSSTox_GSID_45441, 69319-31-9, Nefopam hydrochloride (USAN), 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine, 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine hydrochloride, SMR000514529, SR-01000388442, 5-methyl-1-phenyl-1H,3H,4H,6H-benzo[f]1,4-oxazocine, chloride, 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride, Prestwick_351, Nefopan hydrochloride, Acupan (TN), AC1L4DZD, NCGC00016778-01, CAS-23327-57-3, MLS001210851, MLS001240198, MLS002222204, SCHEMBL122057, CHEMBL1407915, DTXSID7045441, CTK2F4879, KS-00000GSC, MolPort-004-285-328, HMS1568N19, 13669-70-0 (Parent), BCP13749, HY-B1057, Tox21_110606, s4180, SBB057307, AKOS015845828, Tox21_110606_1, API0001381, CCG-220229, CS-4579, MCULE-6729144331, VA10144, Nefopam hydrochloride, >=98% (HPLC), NCGC00094906-06, AC-11999, AK115684, AN-16756, AS-13286, BC203865, H811, AX8144089, KB-246462, ST2412085, 4CH-016300, FT-0082827, FT-0630499, ST50319951, D05133, M-1329, C-18191, I06-0605, SR-01000388442-1, SR-01000388442-4, Nefopam Hydrochloride 1.0 mg/ml in Methanol (as free base), 5-benzoxazocine,5-methyl-1-phenyl-3,4,5,6-tetrahydro-1h-hydrochloride, 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine HCl, 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1), 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocinehydrochloride, 6-methyl-2-phenyl-3-oxa-6-azabicyclo[6.4.0]dodeca-8,10,12-triene hydrochloride, AKOS026749902

ID: 361

InChIKey: CNSUXOYAIZBGRY-AJTZKIQZSA-N
SMILES: C[C@@]12CCC3C(=C1CC(O[C@H]2C4=COC=C4)O)C[C@H]5[C@@H](C([C@@H]([C@@]3(C5=O)C)CC(=O)OC)(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708619
synonyms found at PubChem are:
3,16-DIDEOXYMEXICANOLIDE-3beta-DIOL, KBio2_000987, Spectrum_000507, SpecPlus_000249, Spectrum2_000206, Spectrum3_000076, Spectrum4_001358, Spectrum5_000295, BSPBio_001891, KBioGR_001915, KBioSS_000987, DivK1c_006345, SPBio_000191, CHEMBL3039251, KBio1_001289, KBio2_003555, KBio2_006123, KBio3_001111, NCGC00178923-01, SR-05000002704, SR-05000002704-1, BRD-A84663931-001-03-9

ID: 362

InChIKey: COAJXCLTPGGDAJ-UHFFFAOYSA-N
SMILES: CC(C)NCC(COC1=CC=CC=C1OCC=C)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71172
synonyms found at PubChem are:
Oxprenolol hydrochloride, 6452-73-9, Evinrozit, Ranidrox, Rixiprol, Secondafil, Trepress, Vrachor, Flecor, Drospfta;ome, Slow-Trasicor, Oxprenolol HCl, Oxiprenolol hydrochloride, Oxprenolol.HCl, Ciba 39089Ba, dl-Alprenolol hydrochloride, Ba-39089, CCRIS 1097, C-39089-Ba, EINECS 229-260-5, EINECS 245-358-0, Ba 39089, (+-)-BA 39089, 1-(2-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol hydrochloride, 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol hydrochloride, dl-1-(2-Allylphenoxy)-3-isopropylaminopropan-2-ol hydrochloride, 2-(o-Allyloxyphenoxy)-2-hydroxy-N-isopropyl-1-propylamine hydrochloride, DSSTox_CID_1093, 2-Propanol, 1-(o-(allyloxy)phenoxy)-3-(isopropylamino)-, hydrochloride, (+-)-, 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-, hydrochloride, 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-, hydrochloride, (+-)-, DSSTox_RID_75936, DSSTox_GSID_21093, 2-Propanol, 1-(o-allyloxyphenoxy)-3-isopropylamino-, hydrochloride, (1)-(3-(2-(Allyloxy)phenoxy)-2-hydroxypropyl)isopropylammonium chloride, 1-[(1-methylethyl)amino]-3-{[2-(prop-2-en-1-yloxy)phenyl]oxy}propan-2-ol hydrochloride, 1-[2-(Allyloxy)phenoxy]-3-[isopropylamino]-2-propanol, laracor(hydrochloride), OXPRENOLOLHYDROCHLORIDE, 1-[2-(allyloxy)phenoxy]-3-(isopropylamino)propan-2-ol hydrochloride, 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol;hydrochloride, 3-[(methylethyl)amino]-1-(2-prop-2-enyloxyphenoxy)propan-2-ol, chloride, Okuspurecol (TN), Oxprenolol hydrochloride [USAN:JAN], Oxprenolol hydrochloride [USAN:USP:JAN], AC1L2FOA, AC1Q3DNG, NCGC00016675-01, CAS-6452-73-9, MLS002154132, ARONIS24499, SCHEMBL123517, CHEMBL1200745, DTXSID5021093, CTK8E6918, 6452-71-7 (Parent), BBC/665, MolPort-001-770-529, HMS1571C16, ZX-AS004866, Tox21_110556, 7348AE, SBB058171, Oxprenolol hydrochloride (JP17/USP), AKOS015994696, Tox21_110556_1, API0008993, CCG-221057, KS-1152, LS-7638, MCULE-5603406124, NCGC00179342-03, 22972-97-0, AK129836, AN-19335, SMR001233439, AX8008165, BA-39,089, KB-212502, LS-121645, TR-031398, FT-0630349, ST51015083, D01806, C-18840, SR-01000841263, SR-01000841263-2, Oxprenolol Hydrochloride 1.0 mg/ml in Methanol (as free base), 1-(2-allyloxyphenoxy)-3-(isopropylamino)propan-2-ol hydrochloride, 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol hydrochloride, 1-[(1-Methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-2-propanol hydrochloride, AKOS015907805, I14-25614

ID: 363

InChIKey: COBBNRKBTCBWQP-UHFFFAOYSA-N
SMILES: CN1C2=CC=CC=C2C(=O)C=C1C3=CC4=C(C=C3)OCO4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 353825
synonyms found at PubChem are:
Graveoline, 485-61-0, Graveolin, 2-(benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one, CHEBI:5541, Alkaloid from Ruta angustifolia plant, NSC603064, Foliosine, Prestwick_165, Prestwick0_000674, Prestwick1_000674, Prestwick2_000674, Prestwick3_000674, Oprea1_746980, BSPBio_000767, MLS001048950, SPBio_002688, AC1L733Y, BPBio1_000845, CHEMBL1371756, CTK8G0098, KS-00000TWJ, DTXSID80326593, COBBNRKBTCBWQP-UHFFFAOYSA-N, MolPort-002-511-146, HMS1570G09, HMS2097G09, HMS2268L04, ZINC265501, AKOS002141814, CCG-208356, MCULE-1487710181, NSC-603064, NCGC00016465-01, NCGC00016465-02, NCGC00179443-01, CAS-485-61-0, DS-19520, SMR000386974, C10689, SR-01000737557, 2-(1,3-benzodioxol-5-yl)-1-methylquinolin-4-one, SR-01000737557-3, BRD-K92683369-001-03-6, 1-Methyl-2-(3,4-methylenedioxyphenyl)-4(1H)-quinolinone, 4(1H)-Quinolinone, 2-(1,3-benzodioxol-5-yl)-1-methyl-, 4(1H)-Quinolinone,2-(1,3-benzodioxol-5-yl)-1-methyl-, 2-(1,3-Benzodioxol-5-yl)-1-methyl-4(1H)-quinolinone, 9CI, 2-(1,3-Benzodioxol-5-yl)-1-methyl-4(1H)-quinolinone (graveoline), 2-(2H-1,3-benzodioxol-5-yl)-1-methyl-1,4-dihydroquinolin-4-one

ID: 364

InChIKey: COFJZDUAVQUGRU-UHFFFAOYSA-N
SMILES: CC1=CC(=C(C(=O)O1)CC=C(C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54679299
synonyms found at PubChem are:
2-ISOPRENYL-3-HYDROXY-5-METHYL-a-PYRONE, 4-hydroxy-6-methyl-3-(3-methyl-2-buten-1-yl)-2-pyrone, 16266-64-1, KBio2_003590, Spectrum_000542, SpecPlus_000078, Spectrum2_001959, Spectrum3_001319, Spectrum4_001586, Spectrum5_000272, BSPBio_003017, KBioGR_002172, KBioSS_001022, SPECTRUM240497, DivK1c_006174, SPBio_002057, AC1N0O04, CHEMBL1449088, KBio1_001118, KBio2_001022, KBio2_006158, KBio3_002237, CCG-39468, SDCCGMLS-0066973.P001, NCGC00095545-01, NCGC00095545-02, 2-hydroxy-6-methyl-3-(3-methylbut-2-enyl)pyran-4-one, 4-hydroxy-6-methyl-3-(3-methylbut-2-enyl)pyran-2-one

ID: 365

InChIKey: COKVZBZOKBUBNG-UHFFFAOYSA-M
SMILES: COC1=C[N+](=CC=C1)C2=CC=CC=C2CO.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 10682203

ID: 366

InChIKey: COMTYGQAMQKQCJ-UHFFFAOYSA-N
SMILES: CC(C(COC1=CC=CC2=C1N(C(=O)C=C2OC)C)O)(O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 16219364
synonyms found at PubChem are:
2520-38-9, CHEMBL1257061, DTXSID70585157, COMTYGQAMQKQCJ-UHFFFAOYSA-N, ACM2520389, 8-(2,3-Dihydroxy-3-methoxybutoxy)-4-methoxy-1-methylquinolin-2(1H)-one

ID: 367

InChIKey: COVNOIRYDKHLJD-UHFFFAOYSA-N
SMILES: CC1=NC=CC2=C1NC3=CC=CC=C23.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5487918
synonyms found at PubChem are:
Harman hydrochloride, 21655-84-5, Harmane hydrochloride, 1-methyl-9H-pyrido[3,4-b]indole hydrochloride, UNII-TC01Z184R9, CCRIS 7888, TC01Z184R9, EINECS 244-507-7, 1-Methyl-9H-pyrido(3,4-b)indole hydrochloride, 9H-Pyrido(3,4-b)indole, 1-methyl-, monohydrochloride, Harmane HCl, Prestwick_253, AC1NUPZL, CHEMBL510348, SCHEMBL3764237, 486-84-0 (Parent), DTXSID20176039, MolPort-003-983-584, HMS1569L22, BN0247, AKOS016034226, ACM21655845, 1-methyl-9H-beta-carboline hydrochloride, EN000161, AX8132695, KB-219521, LS-133555, FT-0638140, C-49586, SR-01000075915-3, SR-01000075915-9, 9H-Pyrido[3,4-b]indole,1-methyl-, hydrochloride (1:1)

ID: 368

InChIKey: COVZYZSDYWQREU-UHFFFAOYSA-N
SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2478
synonyms found at PubChem are:
busulfan, 55-98-1, Myleran, Busulphan, Sulphabutin, Leucosulfan, Myelosan, Busulfex, Citosulfan, Mielucin, Misulban, Mitostan, Myeloleukon, Mylecytan, Sulfabutin, Mablin, Mielevcin, Milecitan, Mielosan, Mileran, Buzulfan, 1,4-Dimesyloxybutane, Myeleukon, 1,4-BUTANEDIOL DIMETHANESULFONATE, 1,4-Dimethanesulfonoxybutane, Tetramethylene dimethane sulfonate, butane-1,4-diyl dimethanesulfonate, Busulfano, Busulfanum, Busulphane, Glyzophrol, Myelosanum, 1,4-Dimethylsulfonyloxybutane, 1,4-Butanediol, dimethanesulfonate, 1,4-Dimethanesulfonyloxybutane, 1,4-Bis(methanesulfonoxy)butane, 1,4-Butanediol dimethylsulfonate, 1,4-Dimethylsulfonoxybutane, 1,4-Bis(methanesulfonyloxy)butane, GT 41, Sulfabutin (VAN), Mitosan, CB 2041, NCI-C01592, AN 33501, Methanesulfonic acid, tetramethylene ester, Tetramethylene bis(methanesulfonate), Busulfanum [INN-Latin], 1,4-Dimethanesulphonyloxybutane, Busulfano [INN-Spanish], NSC 750, 4-methylsulfonyloxybutyl methanesulfonate, 1,4-Butanediol dimethanesulphonate, Tetramethylenester kyseliny methansulfonove, 1,4-Dimethanesulfonoxylbutane, C.B. 2041, X 149, Methanesulfonic, Busulfan [INN:JAN], Mylerlan, GT 2041, Myleran tablets, 1,4-Dimethane sulfonyl oxybutane, NSC-750, Butanedioldimethanesulfonate, Tetramethylene bis[methanesulfonate], UNII-G1LN9045DK, CCRIS 418, NSC750, 1,4-Bis[methanesulfonoxy]butane, C6H14O6S2, 1,4-Butanediyl dimethanesulfonate, 4-(methanesulfonyloxy)butyl methanesulfonate, n-Butane-1,3-di(methylsulfonate), 2041 C. B., MYLERAN (TN), 1,4-Butanediol, dimethanesulphonate, EINECS 200-250-2, G.T. 41, BRN 1791786, 1,4-Di(methylsulfonoxy)butane, AI3-25012, G1LN9045DK, CHEBI:28901, COVZYZSDYWQREU-UHFFFAOYSA-N, 1,4-Butanedi yl dimethanesulfonate, Tetramethylenester kyseliny methansulfonove [Czech], Tetramethylene {bis[methanesulfonate]}, NCGC00090905-06, Methanesulfonic acid, tetram ethylene ester, DSSTox_CID_910, alkylating agent: crosslinks guanine residues, 4-((Methylsulfonyl)oxy)butyl methanesulfonate, DSSTox_RID_75857, DSSTox_GSID_20910, BUSULFAN (1,4-BUTANEDIOL, DIMETHANESULFONATE), Busilvex, CAS-55-98-1, SR-01000765405, Bisulfex, Busulfan;, Busulfan/Myleran, Myleran;Busulfex, Busulfex IV, Busulfan [USP:INN:BAN:JAN], HSDB 7605, Prestwick_989, ACMC-20aljs, Spectrum_000092, 2041 C.B., AC1L1DRQ, AC1Q4GRQ, Busulfan, 98% 5g, Spectrum2_000067, Spectrum3_000320, Spectrum4_000259, Spectrum5_000928, acid, tetramethylene ester, CHEMBL820, D07SUG, NCIMech_000192, SCHEMBL4373, Myleran, Busulfex, Busulfan, WLN: WS1&O4OSW1, BSPBio_001920, KBioGR_000698, KBioSS_000512, MLS001076666, Busulfan (Myleran, Busulfex), DivK1c_000847, SPECTRUM1500152, Busulfan (JP17/USP/INN), SPBio_000253, GTPL7136, 1,4-butanedioldimethanesulfonate, DTXSID3020910, COVZYZSDYWQREU-UHFFFAOYSA-, CTK1G9627, HMS502K09, KBio1_000847, KBio2_000512, KBio2_003080, KBio2_005648, KBio3_001420, MolPort-001-783-406, NINDS_000847, HMS1920I07, HMS2091O09, HMS2233H04, HMS3259G15, HMS3370E11, HMS3655A21, HMS3712A20, Pharmakon1600-01500152, 1,{4-Bis[methanesulfonoxy]butane}, HY-B0245, KS-000012XA, ZINC1530572, Tox21_111038, Tox21_201848, Tox21_300318, 1, {4-Bis[methanesulfonoxy]butane}, 2041CB, AC-198, CCG-35458, MFCD00007562, NSC755916, s1692, AKOS003614975, Tox21_111038_1, CS-2224, DB01008, KS-5212, LS-1358, MCULE-1840882522, NC00498, NSC-755916, IDI1_000847, NCGC00090905-01, NCGC00090905-02, NCGC00090905-03, NCGC00090905-04, NCGC00090905-05, NCGC00090905-07, NCGC00090905-08, NCGC00090905-09, NCGC00090905-10, NCGC00090905-11, NCGC00090905-12, NCGC00254038-01, NCGC00259397-01, 2041 C.B, 4-(methylsulfonyloxy)butyl methylsulfonate, AN-16062, BC677894, CPD000058613, NCI60_041640, O994, SAM002554887, SC-22586, SMR000058613, SBI-0051300.P003, 2041 C. B, AB0006846, AB2000224, TC-167599, FT-0083567, FT-0623291, ST45022142, C06862, D00248, K-9954, 15167-EP2272827A1, 15167-EP2272832A1, 15167-EP2275420A1, 15167-EP2295055A2, 15167-EP2295416A2, 15167-EP2295426A1, 15167-EP2295427A1, 15167-EP2298748A2, 15167-EP2298764A1, 15167-EP2298765A1, 15167-EP2298778A1, 15167-EP2305642A2, 15167-EP2308833A2, 15167-EP2308861A1, 15167-EP2311453A1, 15167-EP2311825A1, 15167-EP2311842A2, 15167-EP2316832A1, 15167-EP2316833A1, 32314-EP2280012A2, 32314-EP2281815A1, 32314-EP2292595A1, 32314-EP2292615A1, 32314-EP2301928A1, 32314-EP2301933A1, 32314-EP2305640A2, 32314-EP2305671A1, 32314-EP2311827A1, 32314-EP2311840A1, 4-[(Methylsulfonyl)oxy]butyl methanesulfonate #, AB00051929-10, AB00051929-11, AB00051929_12, AB00051929_14, Busulfan, analytical standard, for drug analysis, Tetramethylenester kyseliny methansulfonove[Czech], I09-1371, SR-01000765405-2, SR-01000765405-3, SR-01000765405-7, Busulfan, European Pharmacopoeia (EP) Reference Standard, Z276508890, InChI=1/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

ID: 369

InChIKey: CPJSUEIXXCENMM-UHFFFAOYSA-N
SMILES: CCOC1=CC=C(C=C1)NC(=O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4754
synonyms found at PubChem are:
phenacetin, Acetophenetidin, 62-44-2, N-(4-Ethoxyphenyl)acetamide, Acetphenetidin, Acetophenetidine, Acetophenetin, Phenacetine, Contradouleur, Achrocidin, Codempiral, Commotional, Contradol, p-Acetophenetidide, Phenazetin, 4-Ethoxyacetanilide, Acetamide, N-(4-ethoxyphenyl)-, 4'-Ethoxyacetanilide, p-Acetophenetidine, Fenacetina, Fenidina, Pertonal, Phenacet, Phenacetinum, Phenacitin, Phenedina, Phenidin, Pyraphen, Fenina, Kalmin, Phenin, p-Acetophenetide, p-Acetphenetidin, p-Ethoxyacetanilide, Phenazetina, Tetracydin, Clistanol, Coriforte, Daprisal, Dasikon, Dolostop, Edrisal, Empiral, Emprazil, Epragen, Fortacyl, Gelonida, Gewodin, Helvagit, Hocophen, Melabon, Melaforte, Pamprin, Paramette, Paratodol, Phenodyne, Pyrroxate, Quadronal, Salgydal, Sanalgine, Seranex, Sinedal, Sinubid, Sinutab, Stellacyl, Synalogos, Treupel, Veganine, Anapac, Fenia, Malex, Tacol, Viden, Xaril, Acetylphenetidin, para-Phenacetin, Bromo seltzer, Kafa, Phenaphen plus, Robaxisal-ph, Aceto-4-phenetidine, Citra-fort, Super Anahist, Dasin ch, Emprazil-C, Acet-p-phenalide, Coryban-D, Paracetophenetidin, Hjorton'S powder, Acet-p-phenetidin, Thephorin A-C, N-Acetyl-p-phenetidine, Buff-A-Comp, Para-acetphenetidin, 1-Acetamido-4-ethoxybenzene, Fiorinal, Sinutabs, Saridon, Aceto-para-phenalide, para-Acetophenetidide, Acetanilide, 4'-ethoxy-, p-Phenetidine, N-acetyl-, Aceto-para-phenetidide, Fenacetin [Czech], Rcra waste number U187, para-Acetophenetidine, Fenacetin, para-Ethoxyacetanilide, Fenacetina [INN-Spanish], N-para-Ethoxyphenylacetamide, CCRIS 496, HSDB 3152, N-Acetyl-4-ethoxyaniline, N-Acetyl-para-phenetidine, Phenacetine [INN-French], Phenacetinum [INN-Latin], UNII-ER0CTH01H9, p-Ethoxyanilid kyseliny octove, p-Ethoxyanilid kyseliny octove [Czech], BRN 1869238, Acetic acid amide, N-(4-ethoxyphenyl)-, 1-Acetyl-p-phenetidin, AI3-00783, Acetamide, N-(4-ethoxyphenol)-, NSC 7651, 4-(Acetylamino)phenetole, EINECS 200-533-0, RCRA waste no. U187, ER0CTH01H9, N-(4-ethoxyphenyl)-acetamide, CHEBI:8050, N-[4-(ethyloxy)phenyl]acetamide, CPJSUEIXXCENMM-UHFFFAOYSA-N, CAS-62-44-2, NCGC00016281-06, DSSTox_CID_1116, DSSTox_RID_75948, DSSTox_GSID_21116, Phenacetin [Analgesic mixtures containing phenacetin], SMR000752916, Phenacetin [INN:JAN], SR-01000787183, Acetophenidin, Terracydin, Phenacetin [USP:INN:JAN], paracetophentidin, Acetylphenetidine, Zactirin compound, p-Acetophenetitide, acet-p-phenal ide, Prestwick_862, Phenacetin, 97%, 4-Ethoxy-acetanilid, N-acetylphenetylamine, 4-Ethoxy-acetanilide, ASA COMPOUND, Butigetic (Salt/Mix), Spectrum_000782, Acetanilide, p-ethoxy-, Phenacetin (JAN/INN), N-Acetyl-p-ethoxyaniline, AC1L1IVN, Prestwick0_000533, Prestwick1_000533, Prestwick2_000533, Prestwick3_000533, Spectrum2_001940, Spectrum3_001404, Spectrum4_000515, Spectrum5_001902, p-Acetophenetidide (8CI), D0O2IE, D0V2MJ, N-Acetyl-4-ethoxyani line, AC1Q37RD, AC1Q37RE, WLN: 2OR DMV1, SCHEMBL23280, 4'-Ethoxyacetanilide, 97%, BSPBio_000545, BSPBio_003048, KBioGR_001089, KBioSS_001262, N-(4-ethoxyphenyl)ethanamide, ZINC602, MLS001304971, MLS002153862, MLS002303055, 4-Ethoxy-1-acetylaminobenzene, ARONIS25011, CHEMBL16073, DivK1c_000580, P-A-C Compound (Salt/Mix), SPECTRUM1500642, N-(4-Ethoxyphenyl) Acetamide, SPBio_001979, SPBio_002466, BPBio1_000601, GTPL7402, Acetamide,N-(4-ethoxyphenyl)-, DTXSID1021116, HMS501M22, KBio1_000580, KBio2_001262, KBio2_003830, KBio2_006398, KBio3_002268, NSC7651, MolPort-000-626-710, NINDS_000580, HMS1569L07, HMS1921M21, HMS2092E14, HMS2096L07, HMS2234P11, HMS3373I02, HMS3651N07, HMS3713L07, Pharmakon1600-01500642, BCP09084, HY-B0476, KS-00000W7P, KS-000046XI, NSC-7651, Phenacetin, >=98.0% (HPLC), Tox21_110347, Tox21_201926, Tox21_302895, BBL004038, BDBM50420191, CCG-39439, LS-269, MFCD00009094, NSC757401, STK011463, AKOS000370201, Phenacetin 1.0 mg/ml in Acetonitrile, Tox21_110347_1, CS-2590, DB03783, MCULE-2069106916, NSC-757401, IDI1_000580, Acetamide, N-(4-ethoxyphenyl)- (9CI), NCGC00016281-01, NCGC00016281-02, NCGC00016281-03, NCGC00016281-04, NCGC00016281-05, NCGC00016281-07, NCGC00016281-08, NCGC00016281-11, NCGC00091376-01, NCGC00091376-02, NCGC00091376-03, NCGC00091376-04, NCGC00091376-05, NCGC00256345-01, NCGC00259475-01, AC-28909, AN-41841, S361, SC-18380, ZB000136, SBI-0051571.P002, AB1009489, Phenacetin, Vetec(TM) reagent grade, 98%, AB00052135, FT-0631277, P1669, S2577, ST45053771, T8098, BIM-0051571.0001, C07591, D00569, Imidazo[4,5-e][1,4]diazapine nucleotide (I), AB00052135_10, AB00052135_11, A833774, AE-848/04969036, SR-01000787183-2, SR-01000787183-3, BRD-K38323065-001-05-8, BRD-K38323065-001-09-0, Phenacetin, United States Pharmacopeia (USP) Reference Standard, Phenacetin Melting Point Standard, United States Pharmacopeia (USP) Reference Standard, 1-Acetyl-p-phenetidin; 4 inverted exclamation marka-Ethoxyacetanilide; N-(4-Ethoxyphenyl)acetamide; p-Acetophenetidide; Acetophenetidin, InChI=1/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12, N4E, Phenacetin melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material

ID: 370

InChIKey: CQOQDQWUFQDJMK-SSTWWWIQSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)OC)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 66414
synonyms found at PubChem are:
2-Methoxyestradiol, 362-07-2, Panzem, 2-Methoxyestradiol-17beta, 2-Hydroxyestradol 2-methyl ether, Estradiol, 2-methoxy-, 2ME2, 2-MeOE2, 2-Hydroxyestradiol 2-methyl ether, 2-ME2, PulmoLAR, 2-Methoxyestra-1,3,5(10)-triene-3,17beta-diol, Panzem NCD, 2-methoxy-17beta-estradiol, UNII-6I2QW73SR5, 2-Methoxy-estradiol, NSC 659853, MLS000028819, (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol, 6I2QW73SR5, CHEMBL299613, 2-Methoxyestradiol (2-MeOE2), CHEBI:28955, CQOQDQWUFQDJMK-SSTWWWIQSA-N, 2-methoxy-estra-1,3,5(10)-triene-3,17beta-diol, Estra-1,3,5(10)-triene-3,17beta-diol, 2-methoxy-, SMR000058478, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-, 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, M 6383, (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol, ESM, 1,3,5(10)-Estratriene-2,3,17-triol 2-methyl ether, (17beta)-2-methoxyestra-1(10),2,4-triene-3,17-diol, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17b)-, 2-methoxyoestradiol, (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol, 2-Methoxy-beta-estradiol, 2-Methoxy-.beta.-estradiol, CCRIS 9405, 1lhw, NSC-659853, K1002_Kinasechem, Opera_ID_634, 2-Methoxyestradiol, powder, D06NYA, AC1L25BI, SCHEMBL8796, Lopac0_000739, 2-ME2, 2-Methoxyestradiol, MLS001076279, MLS006010142, AC1Q7A32, DTXSID3040938, MolPort-003-927-295, HMS2230L22, HMS3262C20, BCP02076, ZINC3818826, Tox21_500739, BDBM50060957, LMST02010035, MFCD00010489, s1233, AKOS015901723, 2-ME2;NSC-659853, 2-Methoxyestradiol, analytical standard, ACN-051090, BCP9000109, CCG-204824, CS-0176, LP00739, SMP2_000045, NCGC00094082-03, NCGC00094082-04, NCGC00261424-01, 4CA-0052, AS-19175, HY-12033, LS-64775, SC-27817, EU-0100739, M2530, X5011, C05302, W-5039, AB00639611-09, AB00639611_10, 2-ME2, 362-07-2, SR-01000076000, 2-methoxy-1,3,5 (10)-estratriene-3,17beta-diol, 2-Methoxyestra-1,3,5(10)-triene-3,17-diol #, SR-01000076000-1, BRD-K44408410-001-20-0, I14-14338, (17?)-2-Methoxyestra-1(10),2,4-triene-3,17-diol, (17?)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol, Estra-1,3,5(10)-triene-3,17.beta.-diol, 2-methoxy-, estra-1(10),2,4-triene-3,17-diol, 2-methoxy-, (17beta)-, B3C40B85-1733-48FE-8418-A39011910D19, Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17.beta.)-

ID: 371

InChIKey: CQOVPNPJLQNMDC-ZETCQYMHSA-N
SMILES: C1=C(NC=N1)C[C@@H](C(=O)O)NC(=O)CCN

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 439224
synonyms found at PubChem are:
L-Carnosine, Carnosine, 305-84-0, beta-Alanyl-L-histidine, Karnozin, Karnozzn, Ignotine, L-Ignotine, N-2-M, UNII-8HO6PVN24W, L-Histidine, beta-alanyl-, Nalpha-(beta-alanyl)-L-histidine, L-HISTIDINE, N-beta-ALANYL-, NSC 524045, BRN 0087671, 8HO6PVN24W, CHEBI:15727, CQOVPNPJLQNMDC-ZETCQYMHSA-N, (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid, N-beta-alanyl-L-histidine, (2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid, EINECS 206-169-9, beta-Alanylhistidine, .beta.-Alanyl-L-histidine, L-Histidine, N-.beta.-alanyl-, Sevitin, betaAla-His, b-Alanylhistidine, beta-Ala-His-OH, H-beta-Ala-His-OH, PubChem6017, beta-alanyl-l-histidin, .beta.-Alanylhistidine, Spectrum_001178, SpecPlus_000374, Spectrum2_000454, Spectrum3_001212, Spectrum4_001673, Spectrum5_000605, 3-aminopropionyl-histidine, bmse000246, bmse001002, D0M9BA, C00386, N-(b-Alanyl)-L-histidine, SCHEMBL33769, BSPBio_002624, KBioGR_002225, KBioSS_001658, 4-25-00-04381 (Beilstein Handbook Reference), KSC911I2F, DivK1c_006470, SPECTRUM1500944, N-(3-Aminopropanoyl)histidine, SPBio_000528, AC1L96X8, AC1Q548S, CHEMBL242948, GTPL4559, CTK8B1422, KBio1_001414, KBio2_001658, KBio2_004226, KBio2_006794, KBio3_002124, L-Carnosine, ~99%, crystalline, MolPort-001-792-080, BCP13131, TNP00340, ZINC2040854, N(alpha)-(beta-alanyl)-L-histidine, ANW-26923, CCG-38696, MFCD00005207, SBB003316, STL466172, AKOS010421481, AKOS015963345, CS-W014210, DB11695, HY-W013494, MCULE-5739145561, RTR-013124, SDCCGMLS-0066726.P001, NCGC00017390-01, NCGC00017390-02, NCGC00142487-01, AC-17084, AC-19690, AS-12570, BC215620, ST057076, TR-013124, A0222, FT-0631923, L-Carnosine, Vetec(TM) reagent grade, 98%, ST24030818, 305C840, SR-05000002473, SR-05000002473-1, (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid, (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid, (S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid, (2~{S})-2-(3-azanylpropanoylamino)-3-(1~{H}-imidazol-4-yl)propanoic acid, (S,Z)-2-((3-amino-1-hydroxypropylidene)amino)-3-(1H-imidazol-5-yl)propanoic acid, 8V0, carnosine zwitterion, CHEBI:57485, N(alpha)-(beta-alaniniumyl)-L-histidinate, (2S)-2-[(3-azaniumylpropanoyl)amino]-3-(1H-imidazol-4-yl)propanoate

ID: 372

InChIKey: CQRYARSYNCAZFO-UHFFFAOYSA-N
SMILES: C1=CC=C(C(=C1)CO)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5146
synonyms found at PubChem are:
salicyl alcohol, 2-HYDROXYBENZYL ALCOHOL, 90-01-7, 2-(Hydroxymethyl)phenol, Saligenin, 2-Methylolphenol, o-Hydroxybenzyl alcohol, Saligenol, Benzenemethanol, 2-hydroxy-, 2-Hydroxymethylphenol, Diathesin, o-Methylolphenol, 2-Hydroxybenzenemethanol, o-(Hydroxymethyl)phenol, Salicylalkohol, salicylic alcohol, Benzyl alcohol, o-hydroxy-, alpha-Hydroxy-o-cresol, alpha,2-Dihydroxytoluene, 2-Hydroxybenzylalcohol, 2-Hydroxybenzylalkohol, Salicyl alcohol [USAN], NSC 3814, UNII-FA1N0842KB, EINECS 201-960-5, .alpha.-Hydroxy-o-cresol, .alpha.,2-Dihydroxytoluene, BRN 1907195, AI3-03990, FA1N0842KB, CHEBI:16464, CQRYARSYNCAZFO-UHFFFAOYSA-N, NCGC00094779-01, Salicyl alcohol (USAN), DSSTox_CID_25843, DSSTox_RID_81166, DSSTox_GSID_45843, CAS-90-01-7, salicylsaure, Saligenine, 2-hydoxybenzyl alcohol, 2-hydroxymethyl-phenol, 2-Hydroxymethyl phenol, PubChem15359, PubChem21869, Spectrum_000944, 2-hydroxy-benzenemethano, 2-hydroxy benzyl alcohol, 2-hydroxy-benzenemethanol, AC1L1JPF, Spectrum2_001311, Spectrum3_000896, Spectrum4_000991, Spectrum5_001190, 2-(hydroxymethyl)-phenol, (2-Hydroxyphenyl)methanol, bmse000768, AC1Q7BY0, SCHEMBL15639, BSPBio_002510, KBioGR_001421, KBioSS_001424, 4-06-00-05896 (Beilstein Handbook Reference), DivK1c_000657, SPECTRUM1500531, SPBio_001401, 2-Hydroxybenzyl alcohol, 99%, AC1Q7C99, CHEMBL280802, ZINC2054, DTXSID9045843, CTK3I9649, HMS502A19, KBio1_000657, KBio2_001424, KBio2_003992, KBio2_006560, KBio3_001812, NSC3814, TOLUENE,ALPHA,2-DIHYDROXY, MolPort-001-759-791, NINDS_000657, HMS1920P12, HMS2092G13, Pharmakon1600-01500531, ACMC-209782, ACT08744, HY-B1419, KS-000009AL, NSC-3814, Tox21_111330, ANW-13632, CCG-39249, HTS001324, MFCD00004617, NSC757317, SBB065036, STL183340, AKOS000249109, Tox21_111330_1, AS00547, BS-3756, CS-4863, MCULE-6070464733, NSC-757317, RP19574, RTC-020742, TRA0063431, IDI1_000657, NCGC00094779-02, NCGC00094779-03, NCGC00094779-05, 4CN-0726, AJ-08126, BR-47595, CJ-00075, K609, KB-24518, LS-43002, SC-75767, ZB000470, SBI-0051508.P003, DB-057178, ST2410043, TC-020742, AM20060376, FT-0686378, ST51037993, EN300-39020, A26232, C02323, D05790, M-6300, AB00052088_02, SR-05000002088, 2-Hydroxybenzyl alcohol, purum, >=98.0% (HPLC), I01-6762, SR-05000002088-1, W-100346, BRD-K08493205-001-02-3, F0001-2205, Z1245664869, InChI=1/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H, SA9

ID: 373

InChIKey: CQZVKMYMXQHTRD-UHFFFAOYSA-M
SMILES: CC(C)C(CO)[N+]1=CC=CC(=C1)OC.[Cl-]

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 10823438

ID: 374

InChIKey: CRDNMYFJWFXOCH-BUHFOSPRSA-N
SMILES: C1=CC=C2C(=C1)/C(=C\3/C(=O)C4=CC=CC=C4N3)/C(=O)N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5359405
synonyms found at PubChem are:
Indirubin, 479-41-4, Indigopurpurin, Couroupitine B, Indigo Red, UNII-V86L8P74GI, NSC 105327, BRN 0088279, V86L8P74GI, C.I. 73200, C16H10N2O2, 397242-72-7, CPD000466311, (E)-[2,3'-biindolinylidene]-2',3-dione, (delta(sup 2,3')-BIINDOLINE)-2',3-DIONE, Q-100514, [2,3'-Biindolinylidene]-2',3-dione, SMR000466311, NSC-105327, INDARUBICIN, AC1NSDZI, EM-A05-INDIRUBIN, SCHEMBL27678, 5-24-08-00507 (Beilstein Handbook Reference), MLS000759416, MLS001424211, MLS002473308, CHEBI:92322, EX-A347, MolPort-005-938-544, HMS2051H20, HMS2234G06, HY-N0117, BDBM50349806, s2386, AKOS015895136, ZINC100015416, (delta2,3'-Biindoline)-2',3-dione, AC-8003, BCP9000788, CCG-101058, CS-3682, DB12379, NC00308, AK128411, LS-43983, SAM001246563, AB0020115, AX8008483, TR-017591, V0881, (delta2,3'-Biindoline)-2',3-dione (8CI), W-2665, (E)-[2,3-BIINDOLINYLIDENE]-2,3-DIONE, AB00639939-06, 479I414, SR-01000759396, I06-0433, SR-01000759396-5, (3E)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- (9CI), Indigo Red|||Couroupitine B|||(3E)-3-(3-Oxo-1H-indol-2-ylidene)-1H-indol-2-one

ID: 375

InChIKey: CRJHBCPQHRVYBS-UHFFFAOYSA-N
SMILES: CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)C.C1=CC=C(C=C1)S(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 36207
synonyms found at PubChem are:
MESORIDAZINE BESYLATE, 32672-69-8, Mesoridazine benzenesulfonate, NC 123, C21H26N2OS2.C6H6O3S, Mesoridazine besylate [USP], CHEBI:6781, 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine monobenzenesulfonate, Serentil (TN), mesoridazine besilate, (+-)-10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine monobenzenesulfonate, Mesoridazine besylate (USP), benzenesulfonic acid; 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfinylphenothiazine, 10H-Phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfinyl)-, (+-)-, monobenzenesulfonate, 10H-Phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfinyl)-, monobenzenesulfonate, Benzenesulfonic acid, compd. with 10-(2-(1-methyl-2-piperidinyl)ethyl)- 2-(methylsulfinyl)ethyl)-10H-phenothiazine (1:1), SMR000466274, Mesoridazine besylate [USAN], SR-01000759425, 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine benzenesulfonate, 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine benzenesulfonate, benzenesulfonic acid;10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfinylphenothiazine, Prestwick_853, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfinyl-phenothiazine, Prestwick0_000529, AC1L1VB9, SCHEMBL41229, MLS000758302, MLS001424031, MLS002222270, mesoridazine monobenzenesulfonate, CHEMBL1201052, CTK8G0808, thioridazine-2-sulfoxide besylate, MolPort-035-395-825, HMS1569J19, HMS2051M09, HMS2096J19, HMS2234G16, HMS3369O09, HMS3393M09, HMS3713J19, Pharmakon1600-01505500, 2538AH, MFCD00800983, NSC760073, CCG-100781, CCG-213471, NC00031, NSC-760073, CPD000466274, LS-32028, SAM001247051, SMR000449304, D00795, J-018829, SR-01000759425-6, Mesoridazine benzenesulfonate, >=98% (HPLC), powder, Mesoridazine besylate, United States Pharmacopeia (USP) Reference Standard, Mesoridazine Besilate (10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsufhinyl)-10H-phenothiazine Besilate)

ID: 376

InChIKey: CRKGMGQUHDNAPB-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 65495
synonyms found at PubChem are:
Sulconazole nitrate, 61318-91-0, 82382-23-8, Sulconazole nitrate salt, Exelderm, Sulconazole mononitrate, sulconazle nitrate, RS 44872, Sulconazole (nitrate), RS-44872, 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate, MLS000028611, RS-44872-00-10-3, SMR000058734, 1-(2-[p-Chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole, (+-)-1-(2,4-Dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazole nitrate, (+-)-1-(2,4-Dichloro-beta-((p-chlorobenzyl)thio)phenethyl)imidazole mononitrate, DSSTox_CID_25490, DSSTox_RID_80911, DSSTox_GSID_45490, C18H16Cl3N3O3S, 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid, 1H-Imidazole, 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate, (+-)-, SR-01000000237, C18H15Cl3N2S.HNO3, Sulconazole nitrate [USAN:JAN], 1-(2-(4-chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, Exelderm (TN), Prestwick_128, Sulconazole(nitrate), Sulconazole nitrate [USAN:USP:JAN], Opera_ID_1591, NCGC00016898-01, AC1L23CV, AC1Q21VV, Sulconazole nitrate (1:x), CAS-61318-91-0, SCHEMBL36906, MLS001146948, MLS002222171, SPECTRUM1501148, CHEBI:9326, Sulconazole nitrate (JAN/USP), 61318-91-0(nitrate), CHEMBL1200348, DTXSID2045490, CTK3E7993, HMS500K22, HY-B1460A, KS-00000XMU, KS-00001FBW, MolPort-003-666-367, HMS1570B21, HMS1921L03, HMS2092H09, HMS2097B21, HMS2232B18, HMS3370H17, HMS3652C18, HMS3714B21, Pharmakon1600-01501148, BCP15962, Tox21_110671, CCG-39015, KM2116, MFCD00058163, NSC757849, s4120, AKOS015897482, Tox21_110671_1, API0007242, CS-5890, KS-1471, NSC-757849, sulconazole, mononitrate, (+-)-isomer, NCGC00018250-06, NCGC00094911-01, NCGC00094911-02, NCGC00094911-03, NCGC00094911-04, AC-26451, AK117764, K466, LS-78325, SC-16173, SC-94845, AB0014236, KB-216959, FT-0659334, ST24037038, D00886, J10283, RS-44872-00-1O-3, A833159, C-46111, I09-1256, SR-01000000237-2, SR-01000000237-4, 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-, I14-14346, 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, 1H-Imidazole, 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-,mononitrate, (+-)-

ID: 377

InChIKey: CRQQGFGUEAVUIL-UHFFFAOYSA-N
SMILES: C(#N)C1=C(C(=C(C(=C1Cl)Cl)Cl)C#N)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 15910
synonyms found at PubChem are:
CHLOROTHALONIL, Tetrachloroisophthalonitrile, 1897-45-6, Daconil, Bravo, m-Tcpn, Nopcocide, 1,3-Dicyanotetrachlorobenzene, 2,4,5,6-Tetrachloroisophthalonitrile, meta-TCPN, Chloroalonil, Clortosip, Dacosoil, Exotherm, Forturf, Repulse, Termil, Faber, Sweep, Exotherm termil, m-Tetrachlorophthalonitrile, Daconil M, Tpn (pesticide), meta-Tetrachlorophthalodinitrile, Bravo 6F, Chlorthalonil, Terraclactyl, 1,3-Benzenedicarbonitrile, 2,4,5,6-tetrachloro-, Daconil 2787, Clortocaf ramato, Bravo-W-75, Daconil Flowable, Bravo 500, 2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile, Nopcocide N-96, Nopcocide N40D & N96, 2,4,5,6-Tetrachloro-3-cyanobenzonitrile, Clorthalonil [German], Tetrachlorisoftalonitril, Caswell No. 215B, Chlorthalonil [German], Isophthalonitrile, tetrachloro-, Vanox, Daconil 2787 flowable fungicide, Daconil 2787 W75, NCI-C00102, DAC 2787, Tetrachlorobenzene-1,3-dicarbonitrile, CCRIS 150, UNII-J718M71A7A, Tetrachlorisoftalonitril [Czech], 2,4,5,6-Tetrachloro-1,3-dicyanobenzene, Isophthalonitrile, 2,4,5,6-tetrachloro-, Chlorothalonil [ANSI:BSI:ISO], Daconil 2787 W-75 Fungicide, HSDB 1546, EINECS 217-588-1, EPA Pesticide Chemical Code 081901, BRN 1978326, Tetrachloroisophthalodinitrile, AI3-28721, CHEBI:3639, Tetrachloro-1,3-dicyanobenzene, 2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile, CRQQGFGUEAVUIL-UHFFFAOYSA-N, J718M71A7A, 1,3-Dicyano-2,4,5,6-tetrachlorobenzene, DSSTox_CID_319, EN300-42790, DSSTox_RID_75510, DSSTox_GSID_20319, W-107745, Clorthalonil, Chlorothalonil, analytical standard, Dakoflo, Jupital, Pillarich, Tuffcide, Farber, Hortyl, Bravo Ultrex, CAS-1897-45-6, Daconil 1000, Bravo 720, Chlorothanonil, Dacobre, Thalonil, 2,4-Dicyanotetrachlorobenzene, Bonide, Siclor, Evade, Tripart faber, Ferti-lome, Tripart ultrafaber, Security fungi-gard, Nopcocide N 96, Nuocide (Salt/Mix), Security Fungi-G ard, Chlorothalonil (TPN), Chlorothalonil solution, Taloberg (Salt/Mix), Tuffcide (Salt/Mix), Dicyanotetrachlorobenzene, Dragon daconil 2787, Echo 75, Spectrum_001557, ACMC-209esy, SpecPlus_000824, Perchloroisophthalonitrile, AC1Q3HKG, Spectrum2_001649, Spectrum3_001896, Spectrum4_000094, Spectrum5_001845, AC1L26VR, m-Tetrachlorophthalodinitrile, SCHEMBL21254, BSPBio_003432, KBioGR_000388, KBioSS_002037, Tetrachloro-m-phthalodinitrile, BIDD:ER0402, DivK1c_006920, SPBio_001777, CHEMBL468167, DTXSID0020319, Pro-care multi-purpose fungicide, CTK8B1087, KBio1_001864, KBio2_002037, KBio2_004605, KBio2_007173, KBio3_002935, Dexol fungicide containing daconil, MolPort-003-931-110, 2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile (8CI)(9CI), ZINC900730, Black leaf lawn & garden fungicide, Green charm multi-purpose fungicide, DAC-2787, Dexol Fung icide Containing Daconil, Sipcam UK rover 500 (Salt/Mix), Green thumb lawn & garden fungicide, Tox21_201687, Tox21_300862, ANW-23456, CCG-39077, LS-959, Rigo's best lawn & garden fungicide, SBB064233, AKOS009158423, FCH2257899, HCH0025711, NE11016, KS-0000025R, QTL1_000080, NCGC00094560-01, NCGC00094560-02, NCGC00094560-03, NCGC00094560-04, NCGC00094560-05, NCGC00094560-06, NCGC00094560-07, NCGC00094560-08, NCGC00254766-01, NCGC00259236-01, SA lawn ornamental & vegetable fungicide, AC-10332, ACM1897456|1, AN-50068, BBV-34553204, CC-25714, O177, Pennington's pride multi-purpose fungicide, ZB015222, Chlorothalonil 10 microg/mL in Acetonitrile, Chlorothalonil 10 microg/mL in Cyclohexane, Ortho multi-purpose fungicide daconil 2787, TC-030115, 2,4,5,6-Tetrachloro-1,3-isophthalonitrile, Chlorothalonil 100 microg/mL in Cyclohexane, FT-0082388, FT-0602408, Benzenedicarbonitrile, 2,4,5,6-tetrachloro-, Ortho Multi-Purpose Fungicide Dacon il 2787, 97C456, C11037, 26836-EP2274983A1, 26836-EP2275422A1, 26836-EP2280009A1, 26836-EP2292608A1, 26836-EP2305033A1, 26836-EP2305662A1, 26836-EP2308857A1, 26836-EP2314583A1, 1,3,4,5-TETRACHLORO-2,6-DICYANOBENZENE, A813350, C-16640, Chlorothalonil, PESTANAL(R), analytical standard, I01-4386, 2,4,5,6-Tetrachloro-1,3-benzenedicarbonitrile (8CI), 2,4,5,6-tetrakis(chloranyl)benzene-1,3-dicarbonitrile, Z2511742144, Chlorothalonil Solution, 10 mg/L, 10 ml (RM, ISO GUIDE 34), InChI=1/C8Cl4N2/c9-5-3(1-13)6(10)8(12)7(11)4(5)2-1, Chlorothalonil solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 101963-73-9, 216082-57-4, 342632-51-3, 462093-27-2

ID: 378

InChIKey: CRTBAVDGJWEWNJ-GKANRWTBSA-M
SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N=C)C(=O)[O-])C.[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 25195407
synonyms found at PubChem are:
Metampicillin sodium salt, METAMPICILLIN SODIUM, UNII-1HE2T55NH5, 1HE2T55NH5, CHEBI:52063, Magnipen, 6489-61-8, Serfabiotic, Metampen, Ocelina, NCGC00094948-01, Serfabiotic (TN), CAS-6489-61-8, DSSTox_CID_25872, DSSTox_RID_81190, DSSTox_GSID_45872, SCHEMBL3767052, CHEMBL3138613, DTXSID6045872, HMS1568P11, HMS2095P11, Tox21_111365, D08191, Sodium (6R)-6-(d-2-methyleneamino-2-phenylacetamido)penicillanate, sodium 6beta-[(2R)-2-(methylideneamino)-2-phenylacetamido]penicillanate, sodium (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-(methylideneamino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, sodium 6beta-[(2R)-2-(methylideneamino)-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate

ID: 379

InChIKey: CSPIFKKOBWYOEX-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC2=CC=CC=C2OC1=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 77553
synonyms found at PubChem are:
3-Acetylcoumarin, 3949-36-8, 3-Acetyl-2H-chromen-2-one, 3-acetylchromen-2-one, Coumarin, 3-acetyl-, 2H-1-Benzopyran-2-one, 3-acetyl-, UNII-ID71XJ0D40, CHEMBL149463, ID71XJ0D40, CSPIFKKOBWYOEX-UHFFFAOYSA-N, NSC31678, 3-acetyl-2-oxochromene, 3-Acetylcoumarine, EINECS 223-541-6, NSC 31678, PubChem8664, AI3-61648, AC1L2TAV, AC1Q5CKV, Maybridge1_000885, Prestwick0_000891, Prestwick1_000891, Prestwick2_000891, Prestwick3_000891, 3-acetylbenzopyran-2-one, 3-Acetylcoumarin, 96%, ACMC-209j5u, BSPBio_000702, 3-acetylbenzo[b]pyran-2-one, MLS002154052, SCHEMBL181862, SPBio_002911, BPBio1_000774, 3-Acetyl-2H-chromen-2-one #, CHEBI:95250, CTK4I1427, HMS544A05, ZINC57909, DTXSID10192627, CHEBI:137384, MolPort-000-141-621, 3-acetyl-2H-1-benzopyran-2-one, HMS1570D04, HMS2097D04, HMS3059M24, ACT07891, 2H-1-Benzopyran-2-one,3-acetyl-, ANW-29104, BBL008903, BDBM50353724, BTB 03234, MFCD00006853, NSC-31678, SBB008168, STK257028, AKOS001083007, CCG-214663, MCULE-8790794091, PS-9795, RP03566, VZ26220, NCGC00016644-01, NCGC00016644-02, NCGC00179470-01, AN-25334, NCI60_002723, SMR000054344, ST096401, ZB002264, CAS-3949-36-8, DB-022157, TR-015790, 2H-1-Benzopyran-2-one, 3-acetyl- (9CI), A2200, AB00513949, EU-0067526, FT-0614886, H2682, Y8981, AE-641/00804058, J-511498, BRD-K26954192-001-03-5, BRD-K26954192-001-06-8, F0150-0014, InChI=1/C11H8O3/c1-7(12)9-6-8-4-2-3-5-10(8)14-11(9)13/h2-6H,1H

ID: 380

InChIKey: CTAUBYSSTAODOD-PKLMIRHRSA-N
SMILES: C=CCN1CCC2=C(C(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)O)Br.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957483
synonyms found at PubChem are:
R(+)-6-Bromo-APB hydrobromide, 139689-19-3, EU-0100216, MLS000862194, CHEMBL1256659, CTK8E6901, AOB5066, DTXSID40474680, r-(+)-6-bromo-apb hydrobromide, Tox21_500216, AKOS025294474, CCG-221520, LP00216, R(+)-6-Bromo-APB hydrobromide, solid, NCGC00093687-01, NCGC00260901-01, SMR000326957, RT-015318, B-135, SR-01000075357, J-007306, SR-01000075357-1, R(+)-6-Bromo-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-, R(+)-6-Bromo-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

ID: 381

InChIKey: CTENFNNZBMHDDG-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1CCN)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 65340
synonyms found at PubChem are:
Dopamine hydrochloride, 62-31-7, 3-Hydroxytyramine hydrochloride, Dopamine HCl, 4-(2-aminoethyl)benzene-1,2-diol hydrochloride, intropin, Dopastat, Revivan, Dynatra, 3,4-Dihydroxyphenethylamine hydrochloride, Cardiosteril, Dopamine.HCl, Dopamine chloride, Dopamine Fresenius, (Dopamine HCl), 2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 4-(2-Aminoethyl)pyrocatechol hydrochloride, m-Hydroxytyramine hydrochloride, 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride, Dopamine (hydrochloride), UNII-7L3E358N9L, 3-Hydroxytyramine, Hydrochloride, ASL-279, P 498, EINECS 200-527-8, NSC 169105, MLS000069419, 3,4-Dihydroxyphenethylamine, HCl, 7L3E358N9L, beta-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 4-(2-Aminoethyl)-1-2-benzenediol, IN1467, 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride (1:1), SMR000059081, C8H11NO2.HCl, 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride, 3-hydroxytyraminium chloride, Abbodop, Inotropin, Rascordin, Tensamin, Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride, NSC169105, 4-(2-aminoethyl)benzene-1,2-diol, chloride, 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride, SR-01000075366, .beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, Actopamin (TN), Dopamine HCl salt, Dopamine hydrochloride [USAN:JAN], Intropin (TN), Dopamine hydrochloride in dextrose 5%, Dopamine hydrochloride and dextrose 5%, 335081-04-4, Dopamine hydrochloride [USAN:USP:JAN], PubChem22727, 3-Hydroxytyramine, HCl, Opera_ID_218, dopamine hydrogen chloride, DSSTox_CID_550, ACMC-1B1TV, Intropin [as hydrochloride], Dopamine, 3-Hydroxytyramine, Dopamini hydrochloridum,(S), CHEMBL1557, DSSTox_RID_75655, DSSTox_GSID_20550, SCHEMBL40951, KSC353A3H, MLS001074180, 51-61-6 (Parent), SPECTRUM1500263, AC1L232Y, CHEBI:4698, SGCUT00110, DTXSID7020550, CTK2F3033, HY-B0451A, Dopamine hydrochloride and dextrose 5% in plastic container, Dopamine hydrochloride in dextrose 5% in plastic container, CTENFNNZBMHDDG-UHFFFAOYSA-N, MolPort-001-769-140, Dopamine hydrochloride (Inotropin), HMS1920I18, KUC104380C, Pharmakon1600-01500263, BCP06611, KS-00000JK7, to_000060, DOPAMINE HCL IN DEXTROSE 5%, Dopamine hydrochloride (JP17/USP), Tox21_201018, Tox21_500586, CCG-40211, MFCD00012898, NSC756749, s2529, SBB003668, DOPAMINE HCL AND DEXTROSE 5%, AKOS008056421, 1, 4-(2-aminoethyl)-, hydrochloride, CS-2562, KS-5304, KSC-10-159, LP00586, LS-7371, MCULE-8844188424, NC00545, NSC-169105, NSC-756749, RTR-021420, 3,4-dihydoxyphenethylamine hydrochloride, CAS-62-31-7, NCGC00093965-01, NCGC00093965-02, NCGC00093965-03, NCGC00093965-04, NCGC00258571-01, NCGC00261271-01, 3,4-dihydroxyphenylethylaminehydrochloride, AC-12190, AN-41839, BC650941, CPD000059081, Dopamine, 3-Hydroxytyramine hydrochloride, H976, KB-32250, SAM002554938, SC-16285, AB0013398, AB1009239, AB2000629, DB-023081, TR-021420, 3,4-dihydroxyphenyl-ethylamine hydrochloride, A0305, AM20080715, EU-0100586, FT-0603260, ST24023111, W0031, dopamine and 3-Hydroxytyramine, Hydrochloride, D00633, H 8502, J10150, M-7455, 2-(3,4-dihydroxyphenyl)ethyl-1-13c-amine hcl, 4-(2-aminoethyl)benzene-1,2-diol,hydrochloride, 2-(3,4-dihydroxyphenyl)-ethylamine hydrochloride, Dopamine hydrochloride, puriss., >=98.5% (AT), SR-01000075366-1, SR-01000075366-8, DOPAMINE HCL IN DEXTROSE 5% IN PLASTIC CONTAINER, F0001-1648, Z262221794, DOPAMINE HCL AND DEXTROSE 5% IN PLASTIC CONTAINER, 963AD780-3E96-47B5-9044-7E59F6C84D67, Dopamine hydrochloride, certified reference material, TraceCERT(R), Dopamine hydrochloride, British Pharmacopoeia (BP) Reference Standard, Dopamine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Dopamine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Dopamine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 1477-71-0, AC1LAOUN, 4-(2-Aminoethyl)catechol, hydrochloride, AKOS024282153, ST053523, 2-(3,4-dihydroxyphenyl)ethylazanium chloride, Dopamine hydrochloride, 99% 5g, AKOS015890746, I01-7909

ID: 382

InChIKey: CTQMJYWDVABFRZ-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=C2N=C1)O)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2817
synonyms found at PubChem are:
5-CHLORO-8-HYDROXYQUINOLINE, 130-16-5, 5-Chloroquinolin-8-ol, Cloxiquine, cloxyquin, 5-Chloro-8-quinolinol, 8-Quinolinol, 5-chloro-, Dermofongin, 5-Chlorooxine, Chlorisept, Dermofungin, 5-Chloro-8-oxyquinoline, Chloroxychinolin, Dermofongin A, 8-Hydroxy-5-chloroquinoline, Monochlorohydroxyquinoline, Cloxyquin [USAN], 5-Chlor-8-chinolinol, 5-Chloro-quinolin-8-ol, Cloxiquinum [INN-Latin], Cloxiquina [INN-Spanish], UNII-BPF36H1G6S, NSC 35083, EINECS 204-978-1, BRN 0005289, BPF36H1G6S, MLS002695956, CTQMJYWDVABFRZ-UHFFFAOYSA-N, Cloxiquine (INN), Cloxiquine [INN], NSC35083, Cloxyquin (USAN), NCGC00095303-02, SMR000274338, DSSTox_CID_25973, DSSTox_RID_81265, DSSTox_GSID_45973, Cloxiquina, Cloxiquinum, CAS-130-16-5, Dermofungin|, 5-Chloroquinophenol, 5-Chloro-8-quinolol, PubChem21921, Spectrum_000820, ACMC-209bhm, AC1L1EJB, Spectrum2_001131, Spectrum3_000361, Spectrum4_000297, Spectrum5_000785, 5-chloranylquinolin-8-ol, Clioquinol EP Impurity A, 5-Chloro-quinoline-8-ol, 5Chloro-8-hydroxyquinoline, Chloroxyquinoline (Related), cid_2817, NCIOpen2_004102, Oprea1_189008, BSPBio_002081, KBioGR_000854, KBioSS_001300, 5-21-03-00279 (Beilstein Handbook Reference), 5-chloro-8-hydroxy-quinoline, KSC490S8H, DivK1c_000163, SCHEMBL115838, SPECTRUM1500202, SPBio_001021, AC1Q78V2, CHEMBL225164, ZINC1209, 5-Chloro-8-quinolinol, 95%, Jsp001829, DTXSID4045973, BCBcMAP01_000058, BDBM76305, CTK3J0983, HMS500I05, KBio1_000163, KBio2_001300, KBio2_003868, KBio2_006436, KBio3_001301, KS-00000IQZ, CHEBI:134818, MolPort-001-757-272, NINDS_000163, 25395-13-5 (hydrochloride), HMS1920A06, HMS2091G14, HMS3091A16, Pharmakon1600-01500202, HY-B0963, Monochlorohydroxyquinoline (Related), NSC53182, STR00716, Tox21_111501, ANW-19160, CCG-39556, MFCD00006788, NSC-35083, NSC-53182, NSC756701, s4559, STK015543, AKOS000121487, Tox21_111501_1, AC-4776, CS-4448, MCULE-2202432462, NE10457, NSC-756701, PS-3329, RP24085, RTR-004115, TRA0014963, IDI1_000163, QTL1_000025, NCGC00095303-01, NCGC00095303-03, NCGC00095303-04, AJ-07976, AN-11668, BAS 00659434, CJ-00035, KB-73461, SC-25590, ZB000274, SBI-0051320.P003, DB-041946, LS-142487, TR-004115, FT-0620307, ST24029461, ST50237100, D03572, AB00051952_05, SR-05000002034, I01-1199, I08-0261, SR-05000002034-1, W-108352, BRD-K46982791-001-02-9, BRD-K46982791-001-04-5, F0001-0401, UNII-Z7Z4BX535U component CTQMJYWDVABFRZ-UHFFFAOYSA-N, InChI=1/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12

ID: 383

InChIKey: CTRLABGOLIVAIY-UHFFFAOYSA-N
SMILES: C1C2=CC=CC=C2N(C3=CC=CC=C3C1=O)C(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 34312
synonyms found at PubChem are:
OXCARBAZEPINE, Trileptal, 28721-07-5, Oxcarbamazepine, Oxacarbazepine, Oxcarbazepina, Oxcarbazepinum, Timox, KIN-493, GP 47680, GP-47680, Oxcarbazepinum [INN-Latin], Oxcarbazepina [INN-Spanish], Oxcarbazepine [INN], Oxcarbazepime, Epilexter, Epliga, 10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide, Trileptal (TN), UNII-VZI5B1W380, 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide, 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide, MLS000084586, EINECS 249-188-8, CHEMBL1068, SMR000048684, CHEBI:7824, VZI5B1W380, 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10-oxo-, 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-oxo-, SPN-804, CTRLABGOLIVAIY-UHFFFAOYSA-N, NCGC00065934-02, O0363, 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide, DSSTox_CID_25703, DSSTox_RID_81075, DSSTox_GSID_45703, W-107033, 10,11-Dihydro-10-oxo-5H-debenz(b,f)azepine-5-carboxamide, 10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide, Oxtellar XR, CAS-28721-07-5, SR-01000612612, oxecarb, Oxcarbazepin, Oxcarbazepine-d4, HSDB 7524, Oxaleptal (TN), Oxtellar (TN), Oxcarbazepine [USAN:USP:INN:BAN], OCBZ, Spectrum_001675, Opera_ID_818, AC1L1RCU, regid866068, Spectrum2_000483, Spectrum3_001669, Spectrum4_000634, Spectrum5_001869, D0QL3P, AC1Q6NA8, Oxcarbazepine (USAN/INN), SCHEMBL35129, BSPBio_003457, KBioGR_001248, KBioSS_002155, cid_34312, MLS000759520, MLS001201742, MLS001424025, MLS006011855, BIDD:GT0078, Desitin brand of oxcarbazepine, SPECTRUM1504243, SPBio_000345, Novartis brand of oxcarbazepine, GTPL7254, ZINC4724, DTXSID0045703, Oxcarbazepine (JAN/USAN/INN), BDBM34179, KBio2_002155, KBio2_004723, KBio2_007291, KBio3_002677, MolPort-001-685-316, Oxcarbazepine, analytical standard, HMS1922H17, HMS2051O04, HMS2090F13, HMS2093E10, HMS2231B12, HMS3369J22, HMS3393O04, HMS3657O11, HMS3713I10, Pharmakon1600-01504243, BB_SC-01874, BCP28260, HY-B0114, Tox21_110983, BBL010789, BG0593, CCG-39509, MFCD00865307, NSC758693, s1391, STK594696, AKOS005516529, Tox21_110983_1, AC-3483, AN-6739, API0003702, CS-1869, DB00776, KS-5197, MCULE-9100100302, NC00088, NSC-758693, Oxcarbazepine, >=98% (HPLC), solid, NCGC00065934-03, NCGC00065934-04, NCGC00065934-05, NCGC00065934-06, BC204104, CC-33410, CPD000048684, LS-60365, SAM001246754, SC-16252, ZB000586, SBI-0206772.P001, AB0012847, AB1004555, AM20040094, FT-0630543, C07492, D00533, EN300-123538, J10384, W-2542, AB00393017-12, AB00393017-14, AB00393017_15, AB00393017_16, 721O075, C-15585, I06-0072, SR-01000612612-4, SR-01000612612-6, BRD-K04196797-001-12-9, 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamide, 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine, 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carbonsaeureamid, 10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide #, Oxcarbazepine, European Pharmacopoeia (EP) Reference Standard, 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide, Oxcarbazepine, United States Pharmacopeia (USP) Reference Standard, 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide; Oxacarbazepine, Oxcarbazepine, Pharmaceutical Secondary Standard; Certified Reference Material, 9-oxo-2-azatricyclo[9.4.0.0;{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide, Oxcarbazepine-13C6 solution, 100 mug/mL in acetonitrile, ampule of 1 mL, certified reference material

ID: 384

InChIKey: CTSPAMFJBXKSOY-UHFFFAOYSA-N
SMILES: CC1=C2C(=C(C3=C1C=CN=C3)C)C4=CC=CC=C4N2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3213
synonyms found at PubChem are:
ellipticine, 519-23-3, Elliptisine, 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole, NSC 71795, TCMDC-125546, 5,11-Dimethyl-6H-pyrido(4,3-b)carbazole, NSC-71795, ICIG 770, 5,11-Dimethylpyrido[4,3-b]carbazole, CCRIS 2003, CP 5, UNII-117VLW7484, NSC71795, EINECS 208-264-0, CHEMBL123, BRN 0221300, MLS000028487, MLS000736786, CHEBI:4776, 6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-, CCG-36483, 117VLW7484, SMR000058370, 6H-Pyrido[4,3-b]carbazole,5,11-dimethyl-, 6H-Pyrido[4,3-b]carbazole, 5,11-dimethyl-, SR-01000003083, elliptecine, Ellipticin, ellipticine, HCl, 5,3-b]carbazole, Prestwick_194, Ellipticine, synthetic, AC1L1FFE, AC1Q2GNZ, AC1Q2QHZ, Opera_ID_1748, Prestwick0_000614, Prestwick1_000614, Prestwick2_000614, Prestwick3_000614, Lopac-E-3380, D00DNY, Probes1_000152, Probes2_000130, cid_3213, Neuro_000031, Lopac0_000531, REGID_for_CID_3213, BSPBio_000548, 5-23-09-00417 (Beilstein Handbook Reference), MLS001076505, SCHEMBL138079, SPBio_002767, BPBio1_000604, CTK8F9429, 55042-50-7 (tartrate), AOB6851, DTXSID30199855, CTSPAMFJBXKSOY-UHFFFAOYSA-N, MolPort-001-839-649, 33668-12-1 (hydrochloride), HMS1569L10, HMS2096L10, HMS2230H10, HMS3261L03, HMS3371L09, BCP13208, ZINC1846592, Tox21_500531, BDBM50004233, BN0731, AKOS024457578, CS-5294, LP00531, VZ29809, NCGC00015411-01, NCGC00015411-02, NCGC00015411-03, NCGC00015411-04, NCGC00015411-05, NCGC00015411-06, NCGC00015411-07, NCGC00015411-08, NCGC00015411-09, NCGC00015411-10, NCGC00022199-03, NCGC00022199-04, NCGC00022199-05, NCGC00261216-01, BC600625, CAS-519-23-3, CC-20854, CJ-30263, HY-15753, NCI60_040685, 5,11-dimethyl-2H-pyrido[4,3-b]carbazole, DB-052047, LS-133282, WLN: T D6 B656 FN LMJ C1 J1, B7382, EU-0100531, FT-0632272, C09154, E 3380, K00071, C-15019, SR-01000003083-2, SR-01000003083-6, BRD-K85985071-001-03-3, BRD-K85985071-001-16-5, BRD-K85985071-001-22-3, 5,11- paragraph signthorn(1/4)x>>u-6H-ssAa currency(2) cent[4,3-b]ssCsso

ID: 385

InChIKey: CTVAVEOYQKVFFY-DUSGSIEYSA-N
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3C4=C(C(=C(C=C4[C@@H]5[C@@H](CC6=C(C=C(C=C6O5)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 467315
synonyms found at PubChem are:
Theasinensin B, CHEMBL159548, 2',2'-BISEPIGALLOCATECHIN MONOGALLATE, Spectrum_000190, SpecPlus_000932, Spectrum2_000177, Spectrum3_000222, Spectrum4_001439, Spectrum5_000298, AC1LAF70, BSPBio_001863, KBioGR_001918, KBioSS_000670, SPECTRUM201506, DivK1c_007028, SPBio_000073, SCHEMBL5097745, KBio1_001972, KBio2_000670, KBio2_003238, KBio2_005806, KBio3_001363, BDBM50442891, CCG-38385, SDCCGMLS-0066850.P001, 2',2'-Bis-Epigallocatechin monogallate, NCGC00178943-01, (2R,3R)-2-{2',3',4,4',5,6-Hexahydroxy-6'-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]biphenyl-2-yl}-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, [(2R,3R)-5,7-dihydroxy-2-[3,4,5-trihydroxy-2-[2,3,4-trihydroxy-6-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]phenyl]phenyl]-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, [(2R,3R)-5,7-dihydroxy-2-[3,4,5-trihydroxy-2-[2,3,4-trihydroxy-6-[(2R,3R)-3,5,7-trihydroxychroman-2-yl]phenyl]phenyl]chroman-3-yl] 3,4,5-trihydroxybenzoate

ID: 386

InChIKey: CUGDOWNTXKLQMD-BQYQJAHWSA-N
SMILES: COC1=CC(=C(C(=C1)O)C(=O)/C=C/C2=CC=CC=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5316793
synonyms found at PubChem are:
Pinostrobin chalcone, 18956-15-5, 2',6'-Dihydroxy-4'-methoxychalcone, 1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one, 77129-49-8, (E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one, EINECS 278-629-7, AC1NSUOD, Chalcone, 2',6'-dihydroxy-4'-methoxy-, CHEMBL317221, SCHEMBL3483741, CUGDOWNTXKLQMD-BQYQJAHWSA-N, MolPort-000-165-366, ZINC4252574, 2-Propen-1-one, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-, (E)-, LMPK12120244, AKOS016009445, MCULE-4781190639, NCGC00090582-01, 2/',6/'-Dihydroxy-4/'-methoxychalcone, 4CN-1376, AJ-49698, AK112313, AX8068340, KB-212704, ST24037034, ST50331405, W1231, (E)-1-(2,6-Dihydroxy-4-methoxy-phenyl)-3-phenyl-propenone, 1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenyl-2-propen-1-one, 2-Propen-1-one, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-, (2E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one, (2E)-1-(2,6-Dihydroxy-4-methoxyphenyl)-3-phenyl-2-propen-1-one #, NCGC00090582-03!(E)-1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one

ID: 387

InChIKey: CUJHOPQCBJBWQL-GJGRSQDYSA-N
SMILES: C[C@@]12CCC(C(=C)C1=CC(=O)O[C@H]2C3=COC=C3)[C@]4(C=CC(=O)C([C@@H]4CC(=O)OC)(C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708516
synonyms found at PubChem are:
DEOXYANDIROBIN, KBio1_001057, Spectrum_000522, SpecPlus_000017, AC1O8FBG, Spectrum2_000232, Spectrum3_000010, Spectrum4_001291, Spectrum5_000041, BSPBio_001619, KBioGR_001661, KBioSS_001002, SPECTRUM100016, DivK1c_006113, SPBio_000303, CHEMBL3039353, CHEBI:93790, KBio2_001002, KBio2_003570, KBio2_006138, KBio3_000699, CCG-39794, SDCCGMLS-0066310.P001, NCGC00179143-01, BRD-A02799884-001-02-9, BRD-A02799884-001-03-7, methyl 2-[(1R,2R)-2-[(1R,8aR)-1-(furan-3-yl)-8a-methyl-5-methylidene-3-oxo-1,6,7,8-tetrahydroisochromen-6-yl]-2,6,6-trimethyl-5-oxocyclohex-3-en-1-yl]acetate

ID: 388

InChIKey: CUQCMXFWIMOWRP-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)N=C(N)N=C(N)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4780
synonyms found at PubChem are:
phenylbiguanide, 1-Phenylbiguanide, Phenyl biguanide, 102-02-3, Phenyldiguanide, Phenylguanide, phenyl diguanide, N-Phenyl-N'-guanylguanidine, N-phenylimidodicarbonimidic diamide, Biguanide, phenyl-, Imidodicarbonimidic diamide, N-phenyl-, UNII-W8PKA3T2I3, BIGUANIDE, 1-PHENYL-, C8H11N5, N-Phenyl-imidocarbonimidic diamide, EINECS 202-998-5, W8PKA3T2I3, CHEMBL13791, CHEBI:75377, P 1426, Imidodicarbonimidicdiamide, N-phenyl-, 1-(diaminomethylidene)-2-phenylguanidine, SR-01000075565, N-phenylbiguanide, N'-phenylbiguanide, Spectrum_000472, Spectrum_001460, Tocris-0969, Lopac-P-120, AC1L1IXT, Spectrum2_001190, Spectrum3_001604, Spectrum4_000058, Spectrum4_000320, Spectrum5_001179, 1-Phenylbiguanide, 98%, ACMC-1C7BO, Biomol-NT_000139, D0H4NK, AC1Q4SR5, NCIOpen2_007801, NCIOpen2_008753, Lopac0_000987, BSPBio_003207, KBioGR_000555, KBioGR_000940, KBioGR_002359, KBioSS_000952, KBioSS_001940, KBioSS_002362, MLS002153449, DivK1c_000282, DivK1c_000749, SCHEMBL467623, SPBio_001239, BPBio1_000156, GTPL2284, SCHEMBL13919685, SCHEMBL19038542, BCBcMAP01_000062, CTK0H1581, HMS500O04, KBio1_000282, KBio1_000749, KBio2_000952, KBio2_001940, KBio2_002359, KBio2_003520, KBio2_004508, KBio2_004927, KBio2_006088, KBio2_007076, KBio2_007495, KBio3_002427, KBio3_002838, 55-57-2 (mono-hydrochloride), DTXSID90144508, cMAP_000031, CUQCMXFWIMOWRP-UHFFFAOYSA-N, MolPort-000-471-471, MolPort-023-283-488, NINDS_000282, NINDS_000749, HMS3043D24, HMS3263E15, N-Phenyliminodicarbonimidic Diamide, 1-carbamimidoyl-3-phenyl-guanidine, Tox21_500987, 7918AF, ANW-14579, BDBM50053596, MFCD00179077, STK110224, ZINC14951244, AKOS002225097, AKOS021982884, CCG-205067, LP00987, MCULE-1047147203, VZ33645, IDI1_000282, IDI1_000749, SMP1_000237, 1-carbamimidamido-N-phenylmethanimidamide, NCGC00015783-01, NCGC00015783-02, NCGC00015783-03, NCGC00015783-04, NCGC00015783-05, NCGC00015783-06, NCGC00024909-01, NCGC00024909-02, NCGC00024909-03, NCGC00024909-04, NCGC00261672-01, AJ-65515, AJ-65516, Br J Pharmacol 90: 229 (1987), KB-59579, LS-43956, SMR000434198, amino[imino(phenylamino)methyl]carboxamidine, TC-103324, EU-0100987, FT-0631545, P-120, P1002, ST50106251, KS-00001553, AB00052412-10, {[amino(phenylamino)methylidene]amino}methanimidamide, I05-2785, J-000539, SR-01000075565-1, BRD-K31491153-003-02-6, BRD-K31491153-003-04-2, 1-(Diaminomethylidene)-2-phenyl-guanidine hydrochloride

ID: 389

InChIKey: CUVGUPIVTLGRGI-UHFFFAOYSA-N
SMILES: C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1228
synonyms found at PubChem are:
100828-16-8, 4-(3-phosphonopropyl)piperazine-2-carboxylic acid, (RS)-CPP, 3-2-Cpp, CARBOXYPEPTIDASE P, 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, (+/-)-CPP, 4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid, [3H]CPP, CHEMBL22304, DL-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid, 9075-64-3, 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, 4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid, (+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid, 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-, 108549-42-4, SR-01000075428, ACMC-20ccug, ACMC-20mqxz, AC1Q5UGB, (+/-)-CPP, solid, (y)-CPP, ACMC-20ms01, D00ZKW, AC1L1B0B, 2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (S)-, 2-Piperazinecarboxylicacid, 4-(3-phosphonopropyl)-, (2R)-, Lopac0_000322, SCHEMBL167788, ( inverted question mark)-CPP, GTPL4082, CTK0I0958, (?)-CPP, CUVGUPIVTLGRGI-UHFFFAOYSA-N, MolPort-003-983-543, HMS3261A05, Tox21_500322, BDBM50002360, BN0161, MFCD00055136, AKOS024456756, CCG-204417, LP00322, NCGC00015179-03, NCGC00015179-04, NCGC00015179-05, NCGC00024482-02, NCGC00024482-03, NCGC00261007-01, LS-110987, RT-005204, C-104, EU-0100322, 2-Piperazinecarboxylicacid, 4-(3-phosphonopropyl)-, J-510489, SR-01000075428-1, SR-01000075428-3, (+)-[3-(3-Carboxypiperazin-1-yl)propyl]phosphonic acid, (CPP)4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid, 3-Phosphono-1-propyl-piperazine-2-carboxylic acid(DL-CPP), 4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid (CPP), (+/-)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid, (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID, R-(-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID, ( inverted exclamation markA)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, ( inverted question mark)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid, 115921-97-6, 120937-13-5, 126947-96-4

ID: 390

InChIKey: CVHZOJJKTDOEJC-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)NS2(=O)=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5143
synonyms found at PubChem are:
saccharin, 81-07-2, o-Sulfobenzimide, Saccharine, o-Benzoic sulfimide, Saccharimide, Benzosulfimide, o-Benzosulfimide, Benzoic sulfimide, Benzosulphimide, Saccharinose, Garantose, Saccharinol, Gluside, Saccharin acid, Benzosulfinide, Hermesetas, Saccharol, Glucid, Saccharin insoluble, 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, Benzoic sulphimide, Saccharina, Kandiset, Sacarina, Sucrette, Zaharina, Saxin, Sykose, Benzo-2-sulphimide, o-Benzoyl sulfimide, Sucre edulcor, Sweeta, o-Benzoic sulphimide, Benzoylsulfonic Imide, o-Sulfobenzoic acid imide, o-Benzosulphimide, Insoluble saccharin, 550 Saccharine, Sacharin, Natreen, o-Benzoyl sulphimide, Anhydro-o-sulfaminebenzoic acid, 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, 2,3-Dihydro-3-oxobenzisosulfonazole, 2-Sulphobenzoic imide, Benzoic acid sulfimide, 1,2-Dihydro-2-ketobenzisosulfonazole, Benzo[d]isothiazol-3(2H)-one 1,1-dioxide, 3-Benzisothiazolinone 1,1-dioxide, 3-Hydroxybenzisothiazole S,S-dioxide, 2,3-Dihydro-3-oxobenzisosulphonazole, 1,2-Dihydro-2-ketobenzisosulphonazole, Sacharin [Czech], 2-Sulfobenzoic acid imide, Rcra waste number U202, Saccharin and salts, Benzosulfimide, O-, Saccharin [USAN], Sulfobenzimide, O-, Saccharin, insoluble, SACCHARIN SODIUM, 3-Hydroxybenzisothiazole-S,S-dioxide, Syncal, o-Benzoic acid sulfimide, Benzo-sulphinide, 1,2-Benzisothiazolin-3-one 1,1-dioxide, UNII-FST467XS7D, 1,1-dioxo-1,2-benzothiazol-3-one, Cristallose, Crystallose, Kristallose, Willosetten, Madhurin, Sucromat, CCRIS 3707, HSDB 669, Sodium saccharin, Saccharin soluble, Sodium saccharide, Sodium saccharine, Soluble saccharin, 1,2-Benzisothiazolin-3-one, 1,1-dioxide, Saccharine soluble, NSC 5349, NSC 5731, EINECS 201-321-0, RCRA waste no. U202, FST467XS7D, Saccharin, sodium salt, Sodium o-benzosulfimide, 1,1-Dioxide-1,2-benzisothiazolin-3-one, AI3-38107, CHEMBL310671, 1,1-Dioxo-1,2-benzisothiazol-3(2H)-one, 1,2-Benzothiazol-3(2H)-one 1,1-dioxide, CHEBI:32111, o-Sulfonbenzoic acid imide sodium salt, CVHZOJJKTDOEJC-UHFFFAOYSA-N, 1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one, 1,1-Diox-1,2-benzisothiazol-3-one, 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, NCGC00094918-03, E954, Saccharin, soluble, 1,2-Benzisothiazoline-3-one 1,1-dioxide, DSSTox_CID_1251, 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one, DSSTox_RID_76039, DSSTox_GSID_21251, 2,3-Dihydro-1,2-benzoisothiazol-3-one-1,1-dioxide, Artificial sweetening substanz gendorf 450, 1,1-Dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one, 128-44-9, Saccharin (only persons who manufacture are subject, no supplier notification), CAS-81-07-2, Saccharin [NF], NSC4867, NSC5731, 2-hydrobenzo[d]isothiazole-1,1,3-trione, Glycophenol, Neosaccharin, SR-01000389315, Benzo-2-sulfiide, O-Benzoylsulfimide, Saccharin nitranion, 2-Sulfobenzoicimide, Ortho sulphobenzamide, O-Sulfobenzoic imide, Sweeta (TN), 2-Sulfobenzoic imide, Spectrum_000213, Saccharin, >=98%, Saccharin, >=99%, Saccharin (JP15/NF), Saccharin (JP17/NF), Spectrum2_001432, Spectrum3_001475, Spectrum4_000449, Spectrum5_001181, D0A0YX, WLN: T56 BSWMVJ, EC 201-321-0, AC1L1JP6, SCHEMBL3816, Saccharin, puriss., 98%, NCIOpen2_005140, NCIOpen2_005180, BSPBio_003029, KBioGR_000838, KBioSS_000693, ARONIS27195, DivK1c_000164, SPECTRUM1501171, SPBio_001564, GTPL5432, DTXSID5021251, BDBM29278, HMS500I06, KBio1_000164, KBio2_000693, KBio2_003261, KBio2_005829, KBio3_002529, NSC5349, 2q38, MolPort-000-881-701, NINDS_000164, HMS1921N03, HMS2092J09, Pharmakon1600-01501171, BCP29068, KS-00000FA4, KS-000048OF, NSC-5349, ZINC2560357, 3-Benzisothiazolinone 1, 1-dioxide, Tox21_111358, Tox21_201880, Tox21_302950, BBL015343, CCG-39011, NSC757878, SBB027246, STK803263, 2, 3-Dihydro-3-oxobenzisosulfonazole, 2,3-Dihydro-3-oxo-Benzisosulfonazole, AKOS000120481, AKOS017272711, Tox21_111358_1, 1, 2-Dihydro-2-ketobenzisosulfonazole, DB12418, LS-1805, MCULE-3632531025, NSC-757878, RP24399, IDI1_000164, 1.2-benzoisothiazole-3-on-1.1-dioxide, Benzisosulfonazole, 2,3-dihydro-3-oxo-, NCGC00094918-01, NCGC00094918-02, NCGC00094918-04, NCGC00094918-05, NCGC00094918-06, NCGC00094918-07, NCGC00256329-01, NCGC00259429-01, AJ-40561, AN-23015, AN-24035, BAS 00293362, BC650677, KB-60378, SC-18191, ST073992, 1,2-benzisothiazoline-3-one-1,1-dioxide, 1.2 -benzoisothiazole-3-on 1.1-dioxide, SBI-0051671.P002, 1, 2-Benzisothiazolin-3-one 1,1-dioxide, ST2412651, 1,2-benzisothiazol-3(2H)-one-1,1-dioxide, B0004, CS-0013120, FT-0674493, H2947, Z1771, Benzo[d]isothiazol-3(2H);-one 1,1-dioxide, 1,2-Benzisothiazol-3(2H)-one -1,1-dioxide, C12283, D01085, 1, 2-Benzisothiazol-3(2H)-one, 1,1-dioxide, 10362-EP2272822A1, 10362-EP2277848A1, 10362-EP2277865A1, 10362-EP2277879A1, 10362-EP2284157A1, 10362-EP2287167A1, 10362-EP2289883A1, 10362-EP2289892A1, 10362-EP2295426A1, 10362-EP2295427A1, 10362-EP2295429A1, 10362-EP2298735A1, 10362-EP2298764A1, 10362-EP2298765A1, 10362-EP2301536A1, 10362-EP2301538A1, 10362-EP2305248A1, 10362-EP2305254A1, 10362-EP2305257A1, 10362-EP2305648A1, 10362-EP2305663A1, 10362-EP2305668A1, 10362-EP2305688A1, 10362-EP2308867A2, 10362-EP2308870A2, 10362-EP2311455A1, 10362-EP2311821A1, 10362-EP2311824A1, 10362-EP2311829A1, 10362-EP2311842A2, 10362-EP2314584A1, 10362-EP2314588A1, 10362-EP2314590A1, 10362-EP2316452A1, 10362-EP2374792A1, 3-keto-2H,3H-1,2-benzisothiazole 1,1-dioxide, 88543-EP2275422A1, 88543-EP2277868A1, 88543-EP2277869A1, 88543-EP2277870A1, 88543-EP2298076A1, 88543-EP2298077A1, 88543-EP2301353A1, 88543-EP2305031A1, 88543-EP2305034A1, 88543-EP2305035A1, 88543-EP2374791A1, AB00052233-04, AB00052233_05, 144417-EP2289518A1, 144417-EP2292231A1, 1,1-Dioxido-3-oxo-2,3-dihydrobenzo[d]isothiazole, 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, 9CI, 2,3-dihydro-1,2-benzisothiazol-3-one-1,1-dioxide, 2,3-dihydro-1lambda,2-benzothiazole-1,1,3-trione, 2,3-dihydro-3-oxo-1,2-benzisothiazol-1,1-dioxide, SR-01000389315-2, W-200289, 03AC8EC2-D02A-464C-A7C3-7CABD643CC1E, 2,3-dihydro-1$l;{6},2-benzothiazole-1,1,3-trione, 2,3-dihydro-1$l^{6},2-benzothiazole-1,1,3-trione, 2,3-dihydro-1lambda6,2-benzothiazole-1,1,3-trione, BRD-K46493214-001-03-4, I14-62592, 1, 2-Benzisothiazolin-3-one, 1,1-dioxide, sodium salt, 1, 2-Benzothiazol-3(2H)-one 1,1-dioxide sodium salt, F0001-2092, Z256708526, 1, 2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt, 1,1-dioxo-1,2-dihydro-1lambda6-benzo[d]isothiazol-3-one, Saccharin, European Pharmacopoeia (EP) Reference Standard, 1,1-Dioxo-1,2-dihydro-1lambda*6*-benzo[d]-isothiazol-3-one, Saccharin, United States Pharmacopeia (USP) Reference Standard, Saccharin, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9, 126987-83-5, 474-91-9, 61255-27-4, 890126-34-8, Mettler-Toledo Calibration substance ME 51143091, Saccharin, traceable to primary standards (LGC)

ID: 391

InChIKey: CVQFAMQDTWVJSV-BAXNFHPCSA-N
SMILES: CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C.C(=C\C(=O)O)\C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5282421
synonyms found at PubChem are:
lisuride maleate, Cuvalit, Lysenyl, Lysenyl bimaleate, Lisuride hydrogen maleate, Lysenyl hydrogen maleate, UNII-UV1635N8XW, Lisuride maleate [JAN], EINECS 243-387-3, UV1635N8XW, R(+)-Lisuride hydrogen maleate, 19875-60-6, Lisuride maleate (JAN), 3-(9,10-Didehydro-6-methylergolin-8-alpha-yl)-1,1-diethylurea maleate (1:1), 3-(9,10-Didehydro-6-methylergolin-8-yl)-1,1-diethylurea hydrogen maleate, 1-((5R,8S)-6-Methyl-9,10-didehydro-8-ergolinyl)-3,3-diethylurea hydrogen maleate, Urea, N'-((8-alpha)-9,10-didehydro-6-methylergolin-8-yl)-N,N-diethyl-, (Z)-2-butenedioate, Urea, 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethyl-, maleate (1:1), CHEBI:31776, R-(+)-Lisuride hydrogen maleate, C20H26N4O.C4H4O4, SCHEMBL364392, CHEMBL1257128, MolPort-006-123-072, 18016-80-3 (Parent), AKOS025142010, LS-159769, D01462, SR-01000075387, SR-01000075387-1, N'-[(8?)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea maleate, R(+)-N'-[(8alpha)-9,10-Didehydro-6-methylergolin-8-yl]-N,N,-diethylurea hydrogen maleate, 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea (2Z)-but-2-enedioate

ID: 392

InChIKey: CWCXONZIEDNVKI-PQBTTZHESA-N
SMILES: CC1(CC2C1CC[C@@]3(CCC4[C@]2(C3)OC(=O)C4CC(=O)O)CBr)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 23847180
synonyms found at PubChem are:
BROMO-3-HYDROXY-4-(SUCCIN-2-YL)-CARYOLANE gamma-LACTONE, BSPBio_002872, CHEMBL3039405, NCGC00178416-01, BROMO-3-HYDROXY-4- (SUCCIN-2-YL)-CARYOLANE gamma-LACTONE

ID: 393

InChIKey: CWJSHJJYOPWUGX-UHFFFAOYSA-N
SMILES: CC(C)OC(=O)NC1=CC(=CC=C1)Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2728
synonyms found at PubChem are:
chlorpropham, 101-21-3, CHLOROPROPHAM, Chloro-IPC, CIPC, Isopropyl m-chlorocarbanilate, Chlorprophame, Elbanil, Isopropyl N-(3-chlorophenyl)carbamate, Metoxon, Nexoval, Preweed, Taterpex, Furloe, Stopgerme-S, Sprout Nip, ChlorIPC, Spud-Nic, Spud-Nie, Chloro-IFK, Triherbicide CIPC, Preventol 56, Prevenol 56, Liro CIPC, Mirvale, Fasco WY-HOE, Furloe 3 EC, Keim-stop, Isopropyl 3-chlorophenylcarbamate, Isopropyl N-(m-chlorophenyl)carbamate, CI-IPC, Isopropyl 3-chlorocarbanilate, Chlor IFC, Chlor IFK, Cl-IFK, Jack Wilson chloro 51(oil), isopropyl (3-chlorophenyl)carbamate, Sprout-nip EC, Unicrop CIPC, Bud Nip, Bud-Nip, Chloro IPC, Chlor IPC, Chlor-IFC, N-(3-Chlorophenyl)isopropyl carbamate, Furloe 3EC, Furloe 4EC, N-3-Chlorophenylisopropylcarbamate, 3-Chlorocarbanilic acid, isopropyl ester, Isopropyl-m-chlorocarbanilate, Caswell No. 510A, Chlorprophame [French], CI-IFK, Isopropyl meta-chlorocarbanilate, Carbamic acid, (3-chlorophenyl)-, 1-methylethyl ester, ENT 18,060, ISOPROPYL N-CHLOROPHENYLCARBAMATE, o-Isopropyl N-(3-chlorophenyl)carbamate, Chlorpropham [BSI:ISO], N-(3-Chlorophenyl)carbamic acid, isopropyl ester, (3-Chlorophenyl)carbamic acid, 1-methylethyl ester, Carbanilic acid, m-chloro-, isopropyl ester, Isopropyl-N-m-chlorophenyl-carbamate, Chlorprophame [ISO-French], Isopropyl-N-3-chlorophenyl carbamate, UNII-0HBU04R8B0, Isopropyl-N-(3-chlorophenyl)carbamate, m-Chlorocarbanilic acid isopropyl ester, N-(3-Chlor-phenyl)-isopropyl-carbamat, N-(3-Chloor-fenyl)-isopropyl carbamaat, N-(3-Cloro-fenil)-isopropil-carbammato, HSDB 981, m-Chlorocarbanilic acid, isopropyl ester, EINECS 202-925-7, NSC 29466, Isopropyl-N-(3-chlorphenyl)-carbamat, 1-Methylethyl(3-chlorophenyl)carbamate, EPA Pesticide Chemical Code 018301, 1-methylethyl (3-chlorophenyl)carbamate, BRN 2211397, propan-2-yl N-(3-chlorophenyl)carbamate, AI3-18060, 0HBU04R8B0, Y 3, CHEBI:34630, Isopropyl-N-(3-chlorphenyl)-carbamat [German], N-(3-Chloor-fenyl)-isopropyl carbamaat [Dutch], N-(3-Chlor-phenyl)-isopropyl-carbamat [German], N-(3-Cloro-fenil)-isopropil-carbammato [Italian], N-(3-Chloro phenyl) carbamate d'isopropyle [French], Isopropyl-N-(3-chlorophenyl) carbamate, N-(3-Chloro phenyl)carbamate d'isopropyle, DSSTox_CID_764, DSSTox_RID_75778, DSSTox_GSID_20764, CAS-101-21-3, Beet, CCRIS 9259, Spud-nip, Unicrop-CIPC, Chloro-ICP, isopropyl-(3-chlorphenyl)carbamat, Chlorpropham CIPC, Chlorpropham solution, Prevenol (Salt/Mix), Spectrum_001883, Gro Stop (Salt/Mix), SpecPlus_000504, AC1L1EBZ, AC1Q3MKB, Furloe Chloro IPC 4EC, N-(3-Chloro phenyl) carbamate d'isopropyle, Spectrum2_000044, Spectrum3_000842, Spectrum4_000682, Spectrum5_002000, Furlow Chloro IPC 20G, Isopropyl chlorocarbanilate, Jack wilson chloro 51 oil, 1-Methylethyl (3-chlorophenyl)carbamate (9CI), SCHEMBL54464, BSPBio_002423, KBioGR_001143, KBioSS_002413, SPECTRUM330051, BIDD:ER0253, DivK1c_006600, Isopropyl m-chloro carbanilate, Isopropyl m-chlorocarb anilate, SPBio_000167, CHEMBL104560, DTXSID7020764, KBio1_001544, KBio2_002407, KBio2_004975, KBio2_007543, KBio3_001923, KS-00000FWX, WLN: GR CMVOY1 & 1, ZINC57368, Chlorpropham, ~95%, crystalline, CWJSHJJYOPWUGX-UHFFFAOYSA-N, MolPort-003-665-450, s214, EBD48798, NSC29466, Chlorocarbanilic acid isopropyl ester, Tox21_201866, Tox21_301139, CCG-39995, NSC-29466, Chlor ocarbanilic acid isopropyl ester, AKOS003369049, propan-2-yl (3-chlorophenyl)carbamate, KS-5118, LS-7135, MCULE-6900965240, Chlorpropham 10 microg/mL in Isooctane, Isopropyl N-(3-Chlorophenyl) Carbamate, NCGC00094538-01, NCGC00094538-02, NCGC00094538-03, NCGC00094538-04, NCGC00094538-05, NCGC00094538-06, NCGC00094538-07, NCGC00255037-01, NCGC00259415-01, AC-11051, NCI60_002445, ZB002091, Chlorpropham 10 microg/mL in Acetonitrile, Chlorpropham 100 microg/mL in Acetonitrile, N-(3-chlorophenyl)(methylethoxy)carboxamide, FT-0631534, ST45024109, 01C213, C14506, M-2048, Chlorpropham, PESTANAL(R), analytical standard, ISOPROPYL-N-(3-CHLORO-PHENYL)-CARBAMATE, N-(3-Chlorophenyl)carbamic Acid Isopropyl Ester, (3-chlorophenyl)carbamic acid 1-methylethyl ester, I01-8055, J-000342, BRD-K59590127-001-02-9, Carbamic acid, N-(3-chlorophenyl)-, 1-methylethyl ester, Carbamic acid, (3-chlorophenyl)-, 1-methylethyl ester (9CI), Chlorpropham Solution, 10 mg/L, 10 ml (RM, ISO GUIDE 34), Isopropyl N-(3-chlorophenyl)carbamate; Isopropyl 3-chlorocarbanilate, Chlorpropham solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard, 11097-02-2

ID: 394

InChIKey: CWKFWBJJNNPGAM-IPZCTEOASA-N
SMILES: C1=CC(=CC=C1CN2C=CN=C2)/C=C/C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6438130
synonyms found at PubChem are:
ozagrel hydrochloride, 78712-43-3, OZAGREL HCl, UNII-W222U960HS, OKY-046, CHEBI:31954, W222U960HS, (E)-3-(4-(1H-Imidazol-1-ylmethyl)phenyl)-2-propenoic acid hydrochloride, CPD000469164, (E)-3-(4-((1H-Imidazol-1-yl)methyl)phenyl)acrylic acid hydrochloride, (E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid hydrochloride, DSSTox_CID_25506, DSSTox_RID_80920, DSSTox_GSID_45506, 74003-18-2, CHEMBL542549, Ozagrel hydrochloride hydrate, 2-Propenoic acid, 3-(4-(1H-imidazol-1-ylmethyl)phenyl)-, monohydrochloride, (E)-, SMR000469164, OKY 046 hydrochloride, OKY-046 hydrochloride, SR-01000597793, OKY046 hydrochloride, ozagrel, monohydrochloride, NCGC00016937-01, CAS-78712-43-3, SCHEMBL36182, SCHEMBL36183, MLS001401435, MLS002222319, AC1O5P37, DTXSID9045506, C13H12N2O2.HCl.H2O, MolPort-003-959-066, HMS1571C19, BCP09493, Tox21_110693, BN0402, s2067, AKOS015895402, Tox21_110693_1, CCG-100969, NC00219, ozagrel, monohydrochloride, (E)-isomer, NCGC00025195-06, AN-36668, DS-11967, SAM001246593, SC-22456, AB2000471, LS-123661, TL8005361, B2116, O0419, C13144, A839477, I06-0662, SR-01000597793-1, SR-01000597793-4, trans-4-[(1-Imidazolyl)methyl]cinnamic Acid Hydrochloride, (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic Acid Hydrochloride, (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride, (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride, 2-Propenoic acid, 3-(4-(1H-imidazol-1-ylmethyl)phenyl)-, monohydrochloride, monohydrate, (E)-, AC1Q1T1Q

ID: 395

InChIKey: CWRVKFFCRWGWCS-UHFFFAOYSA-N
SMILES: C1CCC2=NN=NN2CC1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5917
synonyms found at PubChem are:
Pentylenetetrazol, Pentetrazol, PENTYLENETETRAZOLE, 54-95-5, Metrazole, Cardiazol, 1,5-Pentamethylenetetrazole, Cardiazole, Cardiol, Corazol, Corazole, Korazol, Metrazol, Pentazol, Cardiotonicum, Pentamethazol, Pentetrazole, Cardifortan, Cardosal, Cardosan, Coranormol, Coratoline, Corvasol, Deumacard, Diovascole, Kardiazol, Korazole, Leptazol, Leptazole, Phrenazol, Ventrazol, Cenazol, Corasol, Coryvet, Gewazol, Pentamethylenetetrazol, Pentamethazolum, Pentamethylenetetrazole, Angiazol, Centrazole, Coranormal, Corsedrol, Deamocard, Nauranzol, Naurazol, Nedcardol, Neocardol, Neurazol, Pemetesan, Penetrasol, Pentacard, Pentazolum, Pentemesan, Pentrazol, Pentrolone, Pentrozol, Petrazole, Phrenazone, Tetracor, Tetrazol, Yetrazol, Corisan, Cortis, Corvis, Opticor, Vasorex, Cerebro-nicin, Novo cora-vinco, Cenalene-M, Metalex-P, Corazole (analeptic), 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine, Delzol-W, Pentamethylene-1,5-tetrazole, Tetrazole, pentamethylene-, TT87, Penetratsol, Pentetratsol, Pentetrazolum, Stellacardiol, Stillcardiol, Angioton, Corazolum, Lepazol, Penetiazol, Pentacor, Pentrazole, Petazol, Petezol, alpha,beta-Cyclopentamethylenetetrazole, 6,7,8,9-Tetrahydro-5-azepotetrazole, Tetrazole, (1,5-pentanediyl)-, Pentametilentetrazolo, Pentetrazolo [DCIT], PTZ, 5H-Tetrazolo[1,5-a]azepine, 6,7,8,9-tetrahydro-, Pentetrazolum [INN-Latin], Su-Zol, UNII-WM5Z385K7T, Pentetrazol [INN], Pentamethylenetetrazal, Pentametilentetrazolo [Italian], 6,7,8,9-Tetrahydro-5H-tetrazoloazepine, NSC 5729, EINECS 200-219-3, NSC 66489, 1,2,3,3a-Tetrazacyclohepta-8a,2-cyclopentadiene, BRN 0135492, 5H-Tetrazolo(1,5-a)azepine, 6,7,8,9-tetrahydro-, .alpha.,.beta.-Cyclopentamethylenetetrazole, AI3-23994, WM5Z385K7T, CHEBI:34910, NSC5729, 6,7,8,9-Tetrahydro-5H-tetrazolo(1,5-a)azepine, NSC66489, Pentetrazol (INN), 7,8,9,10-Tetrazabicyclo(5.3.0)-8,10-decadiene, 7,8,9,10-Tetrazabicyclo[5.3.0]-8,10-decadiene, CAS-54-95-5, NCGC00015827-06, 5H-Tetrazoloazepine, 6,7,8,9-tetrahydro-, Tetrazole,5-pentanediyl)-, WLN: T57 ANNNN&TJ, Pentetrazolo, 6,8,9-Tetrahydro-5-azepotetrazole, 6,8,9-Tetrahydro-5H-tetrazoloazepine, 5H-Tetrazoloazepine,7,8,9-tetrahydro-, 5H-Tetrazolo[1, 6,7,8,9-tetrahydro-, 1,3,3a-Tetrazacyclohepta-8a,2-cyclopentadiene, Pentylenetetrazol [NF], 7,9,10-Tetrazabicyclo[5.3.0]-8,10-decadiene, SR-01000076073, Pentavet, 5H,6H,7H,8H,9H-1,2,3,4-tetraazolo[1,5-a]azaperhydroepine, Pentylenetetrazol [NF XIII], Cenalene M, Delzol W, IiEAmicro feminine, Prestwick_382, Ii(3)AEAsso, Pentamethylene tetrazole, Spectrum_000393, SpecPlus_000787, AC1L1LEU, Prestwick0_000162, Prestwick1_000162, Prestwick2_000162, Prestwick3_000162, Spectrum2_001121, Spectrum3_001408, Spectrum4_000242, Spectrum5_001338, Lopac-P-6500, Biomol-NT_000269, Coryvet [veterinary] (TN), DSSTox_CID_21091, DSSTox_RID_79624, DSSTox_GSID_41091, Lopac0_000940, SCHEMBL22674, 1, 5-Pentamethylenetetrazole, 1,5-pentamethylene tetrazole, BSPBio_000023, BSPBio_003056, KBioGR_000644, KBioSS_000873, 4-26-00-01713 (Beilstein Handbook Reference), DivK1c_006883, SPECTRUM2300347, SPBio_000981, SPBio_001944, BPBio1_000027, BPBio1_000860, CHEMBL116943, ZINC1905, DTXSID7041091, KBio1_001827, KBio2_000873, KBio2_003441, KBio2_006009, KBio3_002276, CWRVKFFCRWGWCS-UHFFFAOYSA-N, MolPort-001-783-580, HMS1568B05, HMS2093P18, HMS2095B05, HMS3262L22, HMS3269N13, HMS3712B05, Pharmakon1600-02300347, HY-B1242, KS-000010PC, NSC-5729, ZX-AS005044, Tox21_110234, Tox21_500940, 7467AF, CCG-40268, MFCD00005939, NSC-66489, NSC759592, s4587, SBB058174, STL356056, AKOS005207166, 1,5-IaNC(1/4)x>>u-1H-EAsso, CS-4890, FCH1117372, LP00940, MCULE-7519359961, NSC-759592, NCGC00015827-01, NCGC00015827-02, NCGC00015827-03, NCGC00015827-04, NCGC00015827-05, NCGC00015827-07, NCGC00015827-08, NCGC00015827-09, NCGC00094246-01, NCGC00094246-02, NCGC00094246-03, NCGC00094246-04, NCGC00094246-05, NCGC00261625-01, AK175861, AN-41663, AS-47604, KB-10684, ZB000437, 6,7,8, 9-Tetrahydro-5H-tetrazoloazepine, SBI-0050914.P003, LS-149217, AB00052439, B7152, EU-0100940, FT-0606981, P0046, ST51015107, 5H-Tetrazoloazepine, 6,7,8, 9-tetrahydro-, C13692, D07409, P 6500, 28964-EP2270011A1, 28964-EP2275420A1, 28964-EP2280008A2, 28964-EP2280282A1, 28964-EP2287157A1, 28964-EP2298764A1, 28964-EP2298765A1, 28964-EP2301931A1, 28964-EP2311842A2, AB00052439_04, C-30461, 1,2,3, 3a-Tetrazacyclohepta-8a,2-cyclopentadiene, 6,7,8,9-Tetrahydro-5H-tetraazolo[1,5-a]azepine, 6,7,8,9-Tetrahydro-5H-tetrazolo-[1,5-a]azepine, SR-01000076073-1, SR-01000076073-3, SR-01000076073-5, 6,7,8,9-Tetrahydro-5H-tetraazolo[1,5-a]azepine #, 6,7,8,9-Tetrahydro-5H-tetrazolo- [1,5-a]azepine, 7,8,9,10-Tetrazabicyclo[5.3.0]deca-8,10-diene, BRD-K57718010-001-01-0, BRD-K57718010-001-08-5, I14-19149, {5H-Tetrazolo[1,5-a]azepine,} 6,7,8,9-tetrahydro-, 7,8,9, {10-Tetrazabicyclo[5.3.0]-8,10-decadiene}, 6,7,8,9-EACa-5H-EAsso(2) centmicro feminineOOx inverted question mark

ID: 396

InChIKey: CWVRJTMFETXNAD-JUHZACGLSA-N
SMILES: C1[C@H]([C@H]([C@@H](C[C@@]1(C(=O)O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1794427
synonyms found at PubChem are:
CHLOROGENIC ACID, 327-97-9, 3-Caffeoylquinic acid, Chlorogenate, 3-O-Caffeoylquinic acid, 3-(3,4-Dihydroxycinnamoyl)quinic acid, Heriguard, Hlorogenic acid, Caffeoyl quinic acid, NSC-407296, 3-Caffeoylquinate, UNII-318ADP12RI, 5-O-(3,4-Dihydroxycinnamoyl)-L-quinic acid, CCRIS 1400, Chlorogenic acid (8CI), EINECS 206-325-6, NSC 70861, NSC 407296, 3-trans-Caffeoylquinic acid, Chlorogenicacid, 318ADP12RI, CHEMBL284616, CHEBI:16112, 1,3,4,5-tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate), 3-(3,4-Dihydroxycinnamoyl)quinate, trans-5-O-caffeoyl-D-quinate, Cyclohexanecarboxylic acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1S-(1-alpha,3-beta,4-alpha,5-alpha))-, Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, (1S,3R,4R,5R)-, 3-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid, 5-CQA, 202650-88-2, trans-5-O-Caffeoylquinic acid, 3-O-caffeoyl-D-quinic acid, NSC-70861, 5-Caffeoylquinic acid, 3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy] 1,4,5-trihydroxycyclohexanecarboxylic acid, 5-caffeoyl quinic acid, (1S,3R,4R,5R)-3-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexane-1-carboxylic acid, (1S,3R,4R,5R)-3-((E)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4,5-trihydroxycyclohexanecarboxylic acid, (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid, [1S-(1alpha,3beta,4alpha,5alpha)]-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid, [1S-(1alpha,3beta,4alpha,5alpha)]3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid, Cyclohexanecarboxylic acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1S,3R,4R,5R)-, cyclohexanecarboxylic acid, 3-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, (1S,3R,4R,5R)-, Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, [1S-(1alpha,3beta,4alpha,5alpha)]-, CP chlorogenic acid, (+)-Chlorogenic acid, Chlorogenic acid [MI], Chlorogenic acid [WHO-DD], Hlorogenate, NSC70861, Caffetannic acid, Chlorogenic?acid, NSC407296, caffeoylquinic acid, trans-Caffeic acid 5-o-D-quinate, Prestwick_112, Hoodia Chinese Extract, PubChem13036, Chlorogenic acid, Chiral, Prestwick2_000427, Prestwick3_000427, Spectrum5_000733, bmse000387, D02HCQ, Quinic acid, 5-caffeoyl-, AC1LX54Y, 3-CQA, SCHEMBL19466, BSPBio_000414, BSPBio_003353, SPECTRUM210800, MLS002153805, BIDD:ER0453, 3-CQ, BPBio1_000456, Quinic acid, 3-caffeoyl-, E-, ACon1_000581, CHEBI:95271, Chlorogenic acid (constituent of st. john's wort) [DSC], CWVRJTMFETXNAD-JUHZACGLSA-N, MolPort-001-740-212, MolPort-035-394-873, HMS1569E16, HMS1923C11, HMS2096E16, HMS2235F03, HMS3649E06, ACT03375, ALBB-030169, HY-N0055, ZINC2138728, BDBM50327036, CC-919, CC0158, CCG-38471, MFCD00003862, s2280, AKOS015955866, AC-6032, Chlorogenic acid, >=95% (titration), CS-3766, DB12029, LS-1202, MCULE-8135887819, RL03176, SDCCGMLS-0066467.P001, NCGC00168941-01, NCGC00168941-02, NCGC00168941-03, AJ-33519, AK-49688, AS-12284, BC202916, Chlorogenic acid (constituent of echinacea angustifolia root, echinacea pallida root, echinacea purpurea root and echinacea purpurea aerial parts) [DSC], Cyclohexanecarboxylic acid, 3-(((2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl)oxy)-1,4,5-trihydroxy-, (1S,3R,4R,5R)-, SC-13943, SMR000857273, ST2419179, TL8001703, C00852, J10338, K-7597, 327C979, SR-01000841185, SR-01000946600, D54CAE3D-CDDA-455D-A28E-77FC9EFE4A43, SR-01000841185-4, SR-01000946600-1, BRD-K47114202-001-06-2, I04-11738, 32CF6D13-8F08-485F-B79E-F8A6AC318E07, Chlorogenic acid, primary pharmaceutical reference standard, Chlorogenic acid, European Pharmacopoeia (EP) Reference Standard, 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate, Chlorogenic acid, United States Pharmacopeia (USP) Reference Standard, 3-[(E)-3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid, 3-[3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid, (1R,3S,4S,5S)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid, (1S,3R,4R,5R)-3-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylic acid, (1S,3R,4R,5R)-3-[(E)-3-(3,4-DIHYDROXY-PHENYL)-ACRYLOYLOXY]-1,4,5-TRIHYDROXY-CYCLOHEXANECARBOXYLIC ACID, (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexanecarboxylic acid, (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylicacid, (1S,3R,4R,5R)-3-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexanecarboxylic acid, (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid, (1S,3R,4R,5R,E)-3-(3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4,5-trihydroxycyclohexanecarboxylic acid, edit(1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid

ID: 397

InChIKey: CWXYHOHYCJXYFQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C(=O)NCCC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71651
synonyms found at PubChem are:
Betamipron, 3440-28-6, Benzoyl-beta-alanine, N-Benzoyl-beta-alanine, 3-benzamidopropanoic acid, 3-Benzamidopropionic acid, Betamipron [INN:JAN], 3-(Benzoylamino)propionic acid, N-(phenylcarbonyl)-beta-alanine, beta-Alanine, N-benzoyl-, Betamipronum [INN-Latin], UNII-3W0M245736, BRN 2212769, MLS000069643, CHEMBL1231530, 3-(phenylformamido)propanoic acid, CWXYHOHYCJXYFQ-UHFFFAOYSA-N, NCGC00018241-04, SMR000058183, 3W0M245736, DSSTox_CID_25626, DSSTox_RID_81011, DSSTox_GSID_45626, Betamipronum, CAS-3440-28-6, Betamipron, INN, Benzoyl-b-alanine, Spectrum_001630, Benzoyl-.beta.-alanine, 3-Benzamidopropanoicacid, Betamipron (JAN/INN), Opera_ID_1673, Spectrum2_000434, Spectrum3_001214, Spectrum4_000635, Spectrum5_001432, N-Benzoyl-.beta.-alanine, N-Benzoyl-beta-alanine #, Benzoyl-dl-.beta.-alanine, Betamipron (JP17/INN), 3-benzoylaminopropionic acid, AC1L2GK0, AC1Q75MU, Cambridge id 5117019, N-Benzoyl-b-alanine, 9CI, Oprea1_327957, BSPBio_002628, CBDivE_001204, KBioGR_001250, KBioSS_002110, 4-09-00-00796 (Beilstein Handbook Reference), SCHEMBL605899, SPECTRUM1504244, SPBio_000448, ACMC-209i77, DTXSID0045626, CHEBI:31278, KBio2_002110, KBio2_004678, KBio2_007246, KBio3_002128, ZINC12614, MolPort-000-491-524, HMS1577C12, HMS1922H19, HMS2235A09, HMS3370D05, HMS3652F09, Pharmakon1600-01504244, ALBB-010043, HY-B1127, KS-00000XN3, ZX-AN008895, Tox21_110845, 3-(phenylcarbonylamino)propanoic acid, ANW-27857, BBL000483, BDBM50344964, CCG-39973, CS-443, NSC192714, NSC758708, s4191, STK288042, AKOS000263883, Tox21_110845_1, CS-4674, MCULE-7715802662, NSC-192714, NSC-758708, NCGC00018241-01, NCGC00018241-02, NCGC00018241-03, NCGC00018241-05, NCGC00018241-07, NCGC00021511-03, NCGC00021511-04, AJ-08352, AK113294, AS-13812, BBV-14846988, KB-47728, LS-15813, SBI-0207055.P001, AB0017058, AX8115950, TR-014260, B0099, FT-0679640, ST24028412, ST45137219, D01331, J10360, Y-9240, AB00384351_13, AB00384351_14, C-46717, SR-01000000193, SR-01000000193-2, BRD-K82142815-001-02-7, BRD-K82142815-001-12-6, Z56854345, BYA

ID: 398

InChIKey: CXFIQFGADOTDPF-XKZIYDEJSA-N
SMILES: CC(=CCCC1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4CC5CC6C4(O3)C(C5O)(OC6(C)C)C/C=C(/C)\C(=O)O)CC=C(C)C)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9917275
synonyms found at PubChem are:
TETRAHYDROGAMBOGIC ACID, Spectrum5_000028, BSPBio_002718, SPECTRUM201540, CHEMBL1605700, CCG-38451, NCGC00095544-01, NCGC00095544-02, SR-05000002769, SR-05000002769-1

ID: 399

InChIKey: CXFZFEJJLNLOTA-UHFFFAOYSA-N
SMILES: C[N+](C)(C)CC#CCOC(=O)NC1=CC(=CC=C1)Cl.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5926
synonyms found at PubChem are:
McN-A-343, 55-45-8, MCN A-343 chloride, McN-A 343, MCN A-343, UNII-CW55R761RE, (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride, CW55R761RE, A 343, 4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride, 2-Butyn-1-aminium, 4-((((3-chlorophenyl)amino)carbonyl)oxy)-N,N,N-trimethyl-, chloride, Butyl-1-aminium, 4-((((3-chlorophenyl)amino)carbonyl)oxy)-N,N,N-trimethyl-, chloride, Carbanilic acid, m-chloro-, ester with (4-hydroxy-2-butynyl)trimethylammonium chloride, 4-[(3-chlorophenyl)carbamoyloxy]but-2-ynyl-trimethylazanium chloride, CHEMBL74300, Ammonium, (4-hydroxy-2-butynyl)trimethyl-, chloride, m-chlorocarbanilate, AC1L1LFI, D02BOW, AC1Q1S2A, GTPL290, MLS000859939, SCHEMBL2977744, DTXSID80203532, MolPort-006-822-477, HMS2235M19, HMS3260H16, HMS3372P11, Tox21_500277, MFCD00055068, AKOS024456563, API0006795, CCG-221581, LP00277, 4-{[(3-chlorophenyl)carbamoyl]oxy}-n,n,n-trimethylbut-2-yn-1-aminium chloride, NCGC00093733-01, NCGC00260962-01, LS-18194, SMR000058673, B6715, EU-0100277, C 7041, SR-01000075310, SR-01000075310-1, (4-Hydroxy-2-butynyl)-1-trimethyl-ammonium-3-chloro-carbanilate chloride, (4-Hydroxy-2-butynyl)-1-trimethylammonium-m-chlorocarbanilate chloride, 4-[N-(3-Chlorophenyl)carbamoyloxy]-2--butynyl-trimethyl-ammonium chloride, 4-(N-[3-CHLOROPHENYL]-CARBAMOYLOXY)-2-BUTYNYLTRIMETHYLAMMONIUM CHLORIDE, 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride

ID: 400

InChIKey: CXOFVDLJLONNDW-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1775
synonyms found at PubChem are:
phenytoin, 5,5-DIPHENYLHYDANTOIN, 57-41-0, Diphenylhydantoin, Dilantin, Phenytoine, 5,5-diphenylimidazolidine-2,4-dione, Dihydantoin, Aleviatin, Dilabid, Diphantoin, Diphenylan, Zentropil, Epamin, Diphedan, Fenitoina, Fenylepsin, Lepitoin, Sodanton, Difenin, Dihycon, Lehydan, Diphenylhydatanoin, Dantoinal, Di-Hydan, Dilantine, Dillantin, Diphenine, Diphentyn, Ditoinate, Elepsindon, Epilantin, Fenytoine, Hidantilo, Hidantina, Hidantomin, Hydantoinal, Kessodanten, Phanantin, Phanatine, Phenatine, Phenatoine, Phentytoin, Sodantoin, Sylantoic, Thilophenyl, Zentronal, Auranile, Dantinal, Dantoine, Difetoin, Difhydan, Dintoin, Dintoina, Diphedal, Diphenin, Enkelfel, Epifenyl, Epihydan, Fentoin, Hidantal, Hydantal, Idantoil, Idantoin, Labopal, Phentoin, Ritmenal, Saceril, Sanepil, Silantin, Solantin, Danten, Denyl, Epelin, Epinat, Epised, Eptal, Hidan, Lepsin, Oxylan, Ekko, Ictalis simple, Toin unicelles, Dilantin acid, Dantoinal klinos, Om-Hydantoine, Di-Phetine, Epdantoine simple, Hidantina vitoria, Gerot-epilan-D, Epilan-D, Neosidantoina, Comitoina, Hidantina senosian, Hydantol, Minetoin, Novantoina, Causoin, Convul, Di-Lan, Ekko capsules, Neos-Hidantoina, Om hidantoina simple, TOIN, Epanutin, Phenhydanin, Phenytex, Phenytoinum, Sinergina, Sodanthon, Iphenylhydantoin, Phenytoin-Gerot, Difenilhidantoina, Fenytoin Dak, Didan TDC 250, Dilantin-125, Epdantoin Simple, Phenytoin AWD, Epilan D, 2,4-Imidazolidinedione, 5,5-diphenyl-, Novophenytoin, Antisacer, Diphenat, Hindatal, Hydantin, Fenitoina [INN-Spanish], Phenytoine [INN-French], Phenytoinum [INN-Latin], 5,5-Diphenyl-2,4-imidazolidinedione, Difenilhidantoina [Spanish], Diphenylhydantoine [French], Citrulliamon, 5,5-Dwufenylohydantoina, Diphentoin, Fenitoin, Phenitoin, Solantoin, Solantyl, Comital, Eptoin, Fenantoin Mn Pharma, Fenidantoin s, Diphenylhydantoine, Di-Lan (VAN), Epasmir 5, Diphenylhydantoin (VAN), DILANTIN-30, Sodium Diphenylhydantoinate, Citrullamon, DPH (VAN), Phenhydan, PHENYTEK, Tacosal, PHENYTOIN SODIUM, Fenidantoin "s", 5,5-Diphenylimidazolidin-2,4-dione, 5,5-Diphenyl-imidazolidine-2,4-dione, 5,5-Diphenylhydantoin (IUPAC), 5,5-Dwufenylohydantoina [Polish], Hydantoin, 5,5-diphenyl-, Epasmir "5", Didan-tdc-250, CCRIS 515, CHEBI:8107, elepsi ndon, phenat ine, Dihydan toin, fen toin, taco sal, ictalis simp le, NCI-C55765, 5,5-Diphenylhydantoin (phenytoin), phenytoin (PHN), Dilantin (TN), component of Mebroin, UNII-6158TKW0C5, fenidantoin ''s'', Diphenylan sodium, epasmir ''5'', AI3-52498, CXOFVDLJLONNDW-UHFFFAOYSA-N, Phenytoin [USAN:INN:BAN:JAN], NSC 8722, Extended Phenytoin Sodium, EINECS 200-328-6, MLS000069789, IFLab1_000214, 5,5-diphenyltetrahydro-1H-2,4-imidazoledione, NSC8722, PHENYTOIN SODIUM, EXTENDED, 6158TKW0C5, HSDB 3160, NCGC00021139-03, SMR000059026, PHENYTOIN (5,5-DIPHENYLHYDANTOIN), DSSTox_CID_541, D 4007, DSSTox_RID_75650, DSSTox_GSID_20541, 2-hydroxy-5,5-diphenyl-3,5-dihydro-4H-imidazol-4-one, CAS-57-41-0, 5,5-diphenyl-1,3-diazolidine-2,4-dione, 630-93-3, SR-01000075211, Fenidantoin 's', Fenidantoin (s), Epanutin (TN), Phenytek (TN), Episar (Salt/Mix), Eptoin (TN), Epasmir '5', Epasmir (5), Aladdin (Salt/Mix), Alepsin (Salt/Mix), Epsolin (Salt/Mix), Phenytoin (Lepitoin), Tacosal (Salt/Mix), Phenytoin [USAN:USP:INN:BAN:JAN], Antisacer (Salt/Mix), Epdantoin (Salt/Mix), Epileptin (Salt/Mix), Hydantoin,5-diphenyl-, Spectrum_001105, Fenigramon (Salt/Mix), 5,5-diphenyl hydantoin, Citrullamon (Salt/Mix), Opera_ID_394, 2, 5,5-diphenyl-, Dilantin Infatabs (TN), Dilantin Kapseals (TN), CHEMBL16, Spectrum2_001281, Spectrum3_000890, Spectrum4_000984, Spectrum5_001369, Lopac-D-4007, ACMC-1AMO9, D0E4DW, Epitope ID:117723, AC1L1C7L, SCHEMBL3440, BIDD:PXR0090, Lopac0_000329, Lopac0_000378, Oprea1_373280, BSPBio_001437, KBioGR_001387, KBioSS_001585, KSC493O2R, MLS001074087, MLS002454401, BIDD:GT0625, D4007_SIGMA, DivK1c_000507, Soluble phenytoin (Salt/Mix), SPBio_001281, Phenytoin (JP15/USP/INN), Phenytoin (JP17/USP/INN), AC1Q6G55, AC1Q6G56, GTPL2624, DTXSID8020541, CTK3J3728, KBio1_000507, KBio2_001585, KBio2_004153, KBio2_006721, KBio3_001780, WLN: T5MVMV EHJ ER& ER, 5,5-Diphenylhydantoin, >=99%, MolPort-001-785-683, MolPort-002-365-712, MolPort-023-220-142, NINDS_000507, Phenytoin 1.0 mg/ml in Methanol, HMS1412J16, HMS1694O05, HMS1791H19, HMS1989H19, HMS2089E11, HMS2236J06, HMS3261K17, HMS3402H19, HMS3657O03, Hydantoin, 5,5-diphenyl-(8CI), BCP05960, HY-B0448, Hydantoin, 5,5-diphenyl- (8CI), KS-00000C9F, NSC-8722, ZINC2510358, Tox21_110861, Tox21_202299, Tox21_300281, Tox21_500378, AC-376, ANW-32714, BBL027509, BDBM50003655, BDBM50101816, MFCD00005264, s2525, SBB057224, STK058029, STK182871, STL454130, AKOS000416887, AKOS003245432, Di-Hydan; Dihycon; Dilabid; Diphedan, Tox21_110861_1, CCG-104011, CCG-221682, CL12003, CS-2559, DB00252, LP00378, MCULE-2376673346, NE10390, RTR-037347, TRA0089622, 5,5-di(phenyl)imidazolidine-2,4-dione, IDI1_000507, IDI1_008433, NCGC00015342-01, NCGC00015342-02, NCGC00015342-03, NCGC00015342-04, NCGC00015342-05, NCGC00015342-06, NCGC00015342-07, NCGC00015342-08, NCGC00015342-09, NCGC00015342-10, NCGC00021139-01, NCGC00021139-02, NCGC00021139-04, NCGC00021139-05, NCGC00021139-06, NCGC00021139-07, NCGC00021139-08, NCGC00021139-09, NCGC00021139-10, NCGC00021139-11, NCGC00091492-01, NCGC00091492-02, NCGC00091492-03, NCGC00091492-04, NCGC00091492-05, NCGC00093810-01, NCGC00093810-02, NCGC00254135-01, NCGC00259848-01, NCGC00261063-01, 5,5-?Diphenyl-?2,4-?imidazolidinedione, AJ-36438, AN-15915, BAS 00281572, BC205386, CJ-08570, CPD000059026, SAM002554893, SC-16138, SC-39400, 5,5-Diphenyl-1H-imidazolidine-2,4-dione, AB1000452, KB-196262, TR-037347, D0894, EU-0100378, FT-0699999, ST45024762, EN300-16818, 2,4-Imidazolidinedione, 5,5-diphenyl-(9CI), C07443, D00512, 2,4-Imidazolidinedione, 5,5-diphenyl- (9CI), 5,5-diphenyl-1H-imidazole-2,4(3H,5H)-dione, AB00374253-10, AB00374253-11, AB00374253_13, A831435, SR-01000003141, I14-6452, SR-01000003141-8, SR-01000075211-2, W-105468, BRD-K55930204-001-02-7, BRD-K55930204-236-11-0, Z56786458, 4-hydroxy-5,5-diphenyl-1,5-dihydro-2H-imidazol-2-one, F0020-1370, Phenytoin, European Pharmacopoeia (EP) Reference Standard, Phenytoin, United States Pharmacopeia (USP) Reference Standard, 5,5-Diphenylhydantoin solution, drug standard, 1.0 mg/mL in methanol, Phenytoin, Pharmaceutical Secondary Standard; Certified Reference Material, Phenytoin for system suitability, European Pharmacopoeia (EP) Reference Standard, 125-59-7, InChI=1/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19

ID: 401

InChIKey: CYKYBWRSLLXBOW-CSFFQSOUSA-N
SMILES: C[C@]12CC[C@H](C[C@@H]1CCC3C2CC[C@]4(C3CC[C@@H]4C(=O)CO)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957655
synonyms found at PubChem are:
3-alpha,21-Dihydroxy-5-alpha-pregnan-20-one, 3alpha,21-dihydroxy-5alpha-pregnane-20-one, 21-Hydroxyallopregnanolone, Lopac0_000897, HMS3262D16, Tox21_500897, LMST02030132, CCG-204979, LP00897, NCGC00094213-01, NCGC00094213-02, NCGC00094213-03, NCGC00261582-01, EU-0100897, P 2016, SR-01000076060, SR-01000076060-1

ID: 402

InChIKey: CYRRBQKCXWDLQE-UHFFFAOYSA-N
SMILES: C(C1=CC(C2=CC=CC=C2)=CS1)1C(C(=O)OCC=C)=C(C)NC(C)=C1C(=O)OCC=C

biological descriptors:

CFTR relevance: CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"M Giampieri" "M Mazzei" "M Zacchigna" "P Fossa" "F Cateni" "LJ Galietta" "MT Mazzei" "N Pedemonte"

CID is 46227530
synonyms found at PubChem are:
CHEMBL606151

ID: 403

InChIKey: CYZVRAUHGNBXIO-UHFFFAOYSA-N
SMILES: COC1=C2C(=C(C(=C1)C(=O)O)O)OCO2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4012414
synonyms found at PubChem are:
KBio1_001359, Spectrum_000808, SpecPlus_000319, AC1N1WXI, Spectrum4_001451, Spectrum5_001778, KBioGR_001961, KBioSS_001288, 2-DEMETHYLAPIOLIC ACID, DivK1c_006415, KBio2_001288, KBio2_003856, KBio2_006424, 4-hydroxy-7-methoxy-1,3-benzodioxole-5-carboxylic acid, 4-hydroxy-7-methoxy-2H-1,3-benzodioxole-5-carboxylic acid

ID: 404

InChIKey: CZCIKBSVHDNIDH-UHFFFAOYSA-N
SMILES: CNC(CC1=CNC2=CC=CC=C21)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 914
synonyms found at PubChem are:
N-methyltryptophan, ABRINE (L), 3-(1H-indol-3-yl)-2-(methylamino)propanoic acid, AD-266/41884771, N-Methyltryptophah, methyl-dl-tryptophan, Spectrum_001182, SpecPlus_000633, AC1Q5SKU, Spectrum2_001996, Spectrum3_001529, Spectrum4_001849, Spectrum5_000358, ACMC-209l0p, DL-Tryptophan, N-methyl-, AC1L1AB8, Nalpha-Methyl-L -tryptophan, SCHEMBL18777, BSPBio_002918, KBioGR_002258, KBioSS_001662, DivK1c_006729, SPECTRUM1502236, SPBio_002211, AC1Q40U0, CHEMBL2360657, CHEBI:93824, CTK8G9097, KBio1_001673, KBio2_001662, KBio2_004230, KBio2_006798, KBio3_002418, CZCIKBSVHDNIDH-UHFFFAOYSA-N, HMS1921N12, BCP15809, ABRINE (N-METHYL TRYPTOPHAN), CCG-39534, AKOS023259420, MCULE-7141702170, SDCCGMLS-0066711.P001, VZ33358, NCGC00094555-01, NCGC00094555-02, NCGC00094555-03, NCGC00094555-04, SR-05000002457, 2-(Methylamino)-3-(1H-indole-3-yl)propionic acid, SR-05000002457-1, 3-(1H-indol-3-yl)-2-(methylammonio)propanoate, 3-(1H-indol-3-yl)-2-(methylazaniumyl)propanoate, A829179

ID: 405

InChIKey: CZCROZIJKBXZDP-QGELJSSUSA-N
SMILES: C[C@H]1C2C(CC3C2(CCC4C3CC=C5C4(CC[C@@H](C5)OC(=O)C)C)C)OC16CCC(CO6)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 73354265
synonyms found at PubChem are:
3beta-ACETOXYISOSPIROST-5-ENE

ID: 406

InChIKey: CZHZLRYJEQSRDM-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C=CC3=C2OC(=CC3=O)C4=CC=C(C=C4)[N+](=O)[O-]

biological descriptors:

CFTR relevance: effective CFTR activator

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 11381536
synonyms found at PubChem are:
CHEMBL179925, 71601-18-8, CTK2G2538, DTXSID30464191, BDBM50159605, 2-(4-Nitro-phenyl)-benzo[h]chromen-4-one, 2-(4-Nitrophenyl)-4H-naphtho[1,2-b]pyran-4-one, 4H-Naphtho[1,2-b]pyran-4-one, 2-(4-nitrophenyl)-

ID: 407

InChIKey: CZSAXNDACBPMAB-UHFFFAOYSA-N
SMILES: CN(CCCl)CC1=CC(=C(C(=C1)Cl)NC2=NCCN2)Cl.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957477
synonyms found at PubChem are:
Chloroethylclonidine dihydrochloride, CEC dihydrochloride, 98086-36-3, 70107-07-2, EU-0100195, CHEMBL1478857, LP00195, NCGC00093671-01, Chloroethylclonidine dihydrochloride, solid, SR-01000075727, SR-01000075727-1, 2-[2,6-Dichloro(N-|A-chloroethyl-N-methyl)-4-aminomethyl]phenylimino-2-imidazolidine dihydrochloride

ID: 408

InChIKey: CZTQZXZIADLWOZ-CRAIPNDOSA-N
SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5773
synonyms found at PubChem are:
cephaloridine, cefaloridine, Cefaloridin, Cephaloridin, Cephaloridinum, Cefalorizin, Cepaloridin, Cefaloridinum, Cephalomycine, Cefaloridina, Ceflorin, Cepalorin, Loridine, Kefloridin, 50-59-9, Glaxoridin, Ceporin, Intrasporin, Vioviantine, Ampligram, Ceporan, Ceporine, Cilifor, Deflorin, Faredina, Keflodin, Keflordin, Kefspor, Lloncefal, Sasperin, Sefacin, Verolgin, Betaine cephaloridine, CHEBI:3537, UNII-LVZ1VC61HB, Cefaloridinum [INN-Latin], Cefaloridina [INN-Spanish], N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate, SCH 11527, Aliporina, N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylate, 7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic acid, LILLY 40602, CEPH 87/4, HSDB 3023, EINECS 200-052-6, LVZ1VC61HB, Floridin, CER, C19H17N3O4S2, (6R,7R)-8-oxo-3-(pyridinium-1-ylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, 7-(alpha-(2-Thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine, 7-(Thiophene-2-acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine, (6R,7R)-1-((2-Carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)pyridinium hydroxide, inner salt, 1-((7'-beta-(2-(2-Thienyl)acetamido)-8'-oxo-1'-aza-5'-thiabicyclo(4.2.0)-oct-2'-en-3'-yl)methyl)pyridinium-2'-carboxylate, Pyridinium, 1-((2-carboxy-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, (6R-trans)-, 3-(pyridinium-1-ylmethyl)-7beta-[(2-thienylacetyl)amino]-3,4-didehydrocepham-4-carboxylate, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Pyridinium, 1-((2-carboxy-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)-oct-2-en-3-yl)methyl)-, hydroxide, inner salt, (6R-trans)-, Pyridinium, 1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, hydroxide, inner salt, Cephaloridine [USAN:BAN], Cephaloridine [USAN:USP], Kefloridin (TN), NCGC00094956-01, Cefaloridine [INN], Cephaloridine (USAN), Cefaloridine (JAN/INN), DSSTox_CID_2782, D0F8IO, Epitope ID:120366, AC1L1L3T, SCHEMBL3936, DSSTox_RID_76727, DSSTox_GSID_22782, CHEMBL316157, DTXSID9022782, CZTQZXZIADLWOZ-CRAIPNDOSA-N, Tox21_111368, BDBM50103624, AKOS016014429, DB09008, CAS-50-59-9, AX8120380, KB-277444, LS-132341, C11754, D01075, 7-[.alpha.(2-Thienyl)-acetoamido]-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Pyridinium,1-[[(6R,7R)-2-carboxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt

ID: 409

InChIKey: DANYIYRPLHHOCZ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5280442
synonyms found at PubChem are:
acacetin, 480-44-4, Linarigenin, 5,7-Dihydroxy-4'-methoxyflavone, Acacetine, 4'-Methoxyapigenin, Buddleoflavonol, Linarisenin, Akatsetin, 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, Apigenin 4'-methyl ether, 5,7-Dioxy-4'-methoxyflavone, Apisenin 4'-methyl ether, Apigenin 4'-dimethyl ether, UNII-KWI7J0A2CC, NSC 76061, Flavone, 5,7-dihydroxy-4'-methoxy-, 5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one, ACAETIN, 4'-Methoxy-5,7-dihydroxyflavone, NSC76061, EINECS 207-552-3, KWI7J0A2CC, 5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone, 4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-2-(4-METHOXYPHENYL)-, BRN 0277879, MLS002693970, CHEMBL243664, CHEBI:15335, NSC-76061, SMR001233299, SR-01000841189, Acaceztin, 4-Methylapigenin, 4'-Methylapigenin, Prestwick_49, 4'-O-Methylapigenin, 5,7-Dihydroxy-4, Kinome_3212, Spectrum_000135, Prestwick0_000695, Prestwick1_000695, Prestwick2_000695, Prestwick3_000695, Spectrum5_000930, D0NS1S, AC1NQX12, Acacetin, analytical standard, BSPBio_000849, KBioSS_000595, SPECTRUM200499, 5-18-04-00575 (Beilstein Handbook Reference), MLS002153960, DivK1c_000878, SCHEMBL107712, SPBio_002770, BPBio1_000935, 00017_FLUKA, BCBcMAP01_000082, BDBM23415, CTK8F7490, HMS502L20, KBio1_000878, KBio2_000595, KBio2_003163, KBio2_005731, KS-00001FMT, BIA1211, DTXSID00197383, DANYIYRPLHHOCZ-UHFFFAOYSA-N, Flavone,7-dihydroxy-4'-methoxy-, MolPort-003-665-819, NINDS_000878, ZX-AFC003048, HMS1570K11, HMS1922P12, HMS2097K11, HMS2234J17, HMS3374F03, Acacetin, >=97.0% (HPLC), BCP15815, HY-N0451, ZINC3871358, LMPK12110468, MFCD00016936, AKOS015903365, CCG-208517, CS-5336, MCULE-8773156096, IDI1_000878, SMP1_000001, NCGC00016458-01, NCGC00016458-02, NCGC00016458-03, NCGC00016458-04, NCGC00016458-05, NCGC00095213-01, NCGC00095213-02, NCGC00095213-03, NCGC00179402-01, 4CN-1068, AJ-46344, AK114502, AN-16725, CAS-480-44-4, CC-23624, LS-39600, ST066889, 5,7-DIHYDROXY-4'-METHOXY FLAVONE, WLN: T66 BO EVJ CR DO1& GQ IQ, AB0021899, AX8016262, KB-244293, FT-0645060, N2109, ST24044118, W1621, Flavone, 5,7-dihydroxy-4'-methoxy- (8CI), C01470, 480A444, C-17886, SR-01000841189-3, SR-01000841189-4, BRD-K77685744-001-03-6, BRD-K77685744-001-07-7, I14-19007, I14-21794, 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one #, 4H-1-Benzopyran-4-one,7-dihydroxy-2-(4-methoxyphenyl)-, 5,7-dihydroxy-4 inverted exclamation marka-methoxyflavone, BE7185D3-6331-4E84-8C8E-5D10E505E37A

ID: 410

InChIKey: DATAGRPVKZEWHA-YFKPBYRVSA-N
SMILES: CCNC(=O)CC[C@@H](C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 439378
synonyms found at PubChem are:
L-Theanine, 3081-61-6, Theanine, Theanin, (S)-2-Amino-5-(ethylamino)-5-oxopentanoic acid, N-Ethyl-L-glutamine, Suntheanine, N5-Ethyl-L-glutamine, L-gamma-Glutamylethylamide, N-gamma-Ethyl-L-glutamine, L- Theanine, UNII-8021PR16QO, CCRIS 7326, EINECS 221-379-0, N(5)-ethyl-L-glutamine, NSC 21308, (2S)-2-amino-5-(ethylamino)-5-oxopentanoic acid, CHEBI:17394, DATAGRPVKZEWHA-YFKPBYRVSA-N, 8021PR16QO, n-ethylglutamine, Q-201330, L-Theamine, HSDB 8166, (+)-Theanine, PubChem13022, Spectrum2_001693, Spectrum3_001137, Spectrum4_001984, Spectrum5_000897, Glutamine, N-gamma-ethyl-, Glutamine, N-ethyl-, L-, BSPBio_002633, KBioGR_002514, KSC491M8J, SCHEMBL190716, SPECTRUM1505254, SPBio_001646, AC1L978H, EBD678, CHEMBL3039113, CTK3J1684, KBio3_002133, DTXSID80184817, L-glutamic acid -r-monoethylamide, MolPort-002-317-364, L-Theanine, >=98% (HPLC), BCP28252, KS-00000AG7, ZINC1532828, ANW-26983, CCG-38778, CT-163, CT0238, GM8477, AKOS016842508, AM82649, API0003225, DB12444, RL03081, RTR-013196, SDCCGMLS-0066811.P001, NCGC00178565-01, AC-23939, AJ-26818, AK-87931, AS-12265, KB-53402, SY006013, AB0006097, AB1007083, AX8003929, DB-047911, LS-188302, ST2402786, TR-013196, FT-0628022, N2085, C01047, 081T616, A820634, SR-05000002409, SR-05000002409-1, N|A-Ethyl-L-glutamine, L-Glutamic acid |A-(ethylamide), (2S)-2-azanyl-5-(ethylamino)-5-oxidanylidene-pentanoic acid, C6B5A580-D410-4464-ADB8-543860137D4C, L-Theanine, United States Pharmacopeia (USP) Reference Standard, N5-ethylglutamine, theanine zwitterion, gamma-glutamylethylamide, gamma-glutamyl-ethylamide, SCHEMBL18630592, CHEBI:58128, N(5)-ethyl-L-glutamine zwitterion, CJ-05273, CJ-24266, (2S)-2-azaniumyl-5-(ethylamino)-5-oxopentanoate

ID: 411

InChIKey: DAUAQNGYDSHRET-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C(=O)O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 7121
synonyms found at PubChem are:
3,4-Dimethoxybenzoic acid, 93-07-2, VERATRIC ACID, Benzoic acid, 3,4-dimethoxy-, Dimethylprotocatechuic acid, Veratrylic acid, 3,4-Dimethylprotocatechuic acid, Veratrumenoic acid, 3,4-Dimethoxy-benzoic acid, NSC 7721, UNII-1YY04E7RR4, CHEBI:296881, EINECS 202-215-7, BRN 0518285, 3,4-Dimethoxybenzoic acid (Veratric acid), 1YY04E7RR4, CHEMBL118903, DAUAQNGYDSHRET-UHFFFAOYSA-N, 3,4-dimethoxybenzoes, PubChem13788, Spectrum_000512, AC1Q4FEP, Spectrum2_001082, Spectrum3_001774, Spectrum4_001582, Spectrum5_000264, 3,4 dimethoxybenzoic acid, 3,4-dimethoxybenzoic-acid, 3,4dimethoxy benzoic acid, bmse010207, Epitope ID:119695, EC 202-215-7, AC1Q46MI, 3,4-Dimethoxy benzoic acid, ACMC-1CA67, BSPBio_003267, KBioGR_002164, KBioSS_000992, SPECTRUM212140, KSC489M8H, MLS002207141, SCHEMBL114848, SPBio_001124, AC1L1O21, 3,4-bis(methyloxy)benzoic acid, DTXSID6059077, CTK3I9683, KBio2_000992, KBio2_003560, KBio2_006128, KBio3_002768, NSC7721, MolPort-000-871-567, Protocatechuic Acid Dimethyl Ether, ZINC392017, ACN-S002779, NSC-7721, ANW-13645, BBL025942, BDBM50336487, CCG-39276, CD0096, MFCD00002500, SBB040520, STK397279, 3,4-Dimethoxybenzoic acid, >=99%, AKOS000119433, BS-3989, MCULE-2108800864, RP24315, RTR-038447, SDCCGMLS-0066972.P001, TRA0004863, NCGC00095539-01, NCGC00095539-02, 3,4-Dimethoxybenzoic acid; Veratric acid, AC-10246, AJ-21207, AN-24252, KB-28352, LS-37122, SMR000112092, AB1002355, ST2410268, TL8000030, TR-038447, CS-0018327, D0631, FT-0648222, ST45103469, T8296, AZ0001-0140, SR-05000002417, I01-0178, SR-05000002417-1, W-100257, BRD-K14520048-001-02-6, BRD-K14520048-001-04-2, F2191-0107, Z235345619, InChI=1/C9H10O4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5H,1-2H3,(H,10,11, TWO

ID: 412

InChIKey: DAVNRFCJMIONPO-UKRRQHHQSA-N
SMILES: CN1CC(=C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CO

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 440904
synonyms found at PubChem are:
ELYMOCLAVINE, UNII-5LR46DLO0D, 548-43-6, 5LR46DLO0D, Dihydrolysergol, 8,9-Didehydro-6-methylergoline-8-methanol, EINECS 208-948-9, NSC 109431, BRN 0030650, Spectrum5_001634, AC1L9A5M, 4-23-00-02716 (Beilstein Handbook Reference), SCHEMBL183704, SPECTRUM1800052, CHEBI:4777, CHEMBL3706997, CTK3G5357, ZINC896007, 91106-37-5, C06068, Methanol, (8,9-didehydro-6-methylergolin-8-yl)-

ID: 413

InChIKey: DAXSYTVXDSOSIE-HNJRGHQBSA-N
SMILES: CC1=C([C@@]2(CC[C@H]([C@@]([C@H]2CC1)(C)CO)O)C)CCC3=CCOC3=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 21679042
synonyms found at PubChem are:
Deoxyandrographolide, 79233-15-1, ANDROGRAPHOLIDE, DEOXY-, DTXSID60616868, MolPort-005-938-522, HY-N0857, 9342AF, ZINC21992845, AKOS015965180, CS-3655, AC-20219, AN-36619, 3-{2-[(4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]ethyl}furan-2(5H)-one, 4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one

ID: 414

InChIKey: DAZAXBYJPXKJJL-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=NN=C(N2N)C3=CC=CC=C3

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 229821
synonyms found at PubChem are:
3,5-Diphenyl-4H-1,2,4-triazol-4-amine, 3049-45-4, 3,5-Diphenyl-[1,2,4]triazol-4-ylamine, CHEMBL1531266, 3,5-diphenyl-1,2,4-triazole-4-ylamine, diphenyltriazolamine, NSC23819, AC1Q4XCK, CBMicro_011722, AC1L5I5M, Cambridge id 5109711, MLS000532644, SCHEMBL12841647, CTK4G5321, ZINC54242, DTXSID50282011, DAZAXBYJPXKJJL-UHFFFAOYSA-N, MolPort-002-130-967, diphenyl-1,2,4-triazol-4-amine, HMS2163A19, KS-000020PA, SMSF0003334, 9640AD, BDBM50001684, NSC-23819, SBB052026, STK766340, AKOS001731206, diphenyl-4H-1,2,4-triazol-4-amine, ACM3049454, CB14925, MCULE-6645590961, RP13579, 3,5-diphenyl-1,2,4-triazol-4-amine, 4-amino-3,5-diphenyl-1,2,4-triazole, AJ-09184, SMR000137583, ZB001566, BIM-0011605.P001, ST4068143, TR-031221, FT-0680656, 4H-1,2,4-Triazol-4-amine,3,5-diphenyl-, 3,5-Diphenyl-4H-1,2,4-triazol-4-amine #, 8P-933, SR-01000535856, J-511374, SR-01000535856-1, A2681/0114261

ID: 415

InChIKey: DBABZHXKTCFAPX-UHFFFAOYSA-N
SMILES: CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4911
synonyms found at PubChem are:
probenecid, 57-66-9, 4-(Dipropylsulfamoyl)benzoic acid, Probenecid acid, Probecid, Benecid, Benemid, Benuryl, Probalan, Probenemid, Probexin, Prolongine, Tubophan, Uricosid, Apurina, Proben, Synergid R, p-(Dipropylsulfamoyl)benzoic acid, Probampacin, Probenecida, Probenecide, Probenecidum, 4-[(dipropylamino)sulfonyl]benzoic acid, Benemide, Probenid, Robenecid, Polycillin-BRB, probenicid, 4-((Dipropylamino)sulfonyl)benzoic acid, Polycillin-PRB, 4-(Di-n-propylsulfamoyl)benzoesaeure, 4-(N,N-Dipropylsulfamoyl)benzoesaeure, Benzoic acid, 4-[(dipropylamino)sulfonyl]-, Probenecide [INN-French], Probenecidum [INN-Latin], Probenecida [INN-Spanish], NCI-C56097, Benzoic acid, p-(dipropylsulfamoyl)-, Panuric, Parabenem, Sulprin, Bencid, Urocid, 4-(N,N-Dipropylsulfamoyl)benzoic Acid, p-(Dipropylsulfamyl)benzoic acid, NSC 18786, Benemid (TN), Probenecid [INN:BAN:JAN], Col-BENEMID, C13H19NO4S, CCRIS 3643, CHEBI:8426, Probenecid (Benemid), UNII-PO572Z7917, HSDB 3387, p-[Dipropylsulfamoyl]benzoic acid, Benzoic acid, 4-((dipropylamino)sulfonyl)-, EINECS 200-344-3, ColBenemid (component of), CHEMBL897, ColBenemid (co mponent of), BRN 2815775, AI3-50078, MLS000028496, Polycillin-PRB (component of), 4-Dipropylsulfamoyl-benzoic acid, DBABZHXKTCFAPX-UHFFFAOYSA-N, PO572Z7917, CAS-57-66-9, NCGC00016251-08, SMR000058280, DSSTox_CID_1188, DSSTox_RID_75998, DSSTox_GSID_21188, Probenecid Weimer, Pro-Cid, SR-01000003108, Probenecid [USP:INN:BAN:JAN], Prestwick_809, Benuryl (TN), Probenecid Major Brand, Probenecid Martec Brand, Probenecid Parmed Brand, Probenecid Zenith Brand, Spectrum_000834, ColBenemid (Salt/Mix), Opera_ID_677, ICN Brand of Probenecid, AC1Q2XQM, AC1Q2XQN, Prestwick0_000542, Prestwick1_000542, Prestwick2_000542, Prestwick3_000542, Spectrum2_001294, Spectrum3_000554, Spectrum4_000486, Spectrum5_001419, IDIS Brand of Probenecid, Major Brand of Probenecid, Merck Brand of Probenecid, D0L7FM, Epitope ID:180853, Martec Brand of Probenecid, Parmed Brand of Probenecid, Zenith Brand of Probenecid, SCHEMBL3663, Biokanol Brand of Probenecid, Polycillin-PRB (Salt/Mix), BIDD:PXR0092, Oprea1_416955, WLN: QVR DSWN3&3, BSPBio_000583, BSPBio_002227, KBioGR_000971, KBioSS_001314, MLS001076472, BIDD:GT0626, DivK1c_000056, SPECTRUM1500502, Ophthalmic Brand of Probenecid, SPBio_001327, SPBio_002504, Valdecasas Brand of Probenecid, AC1L1J86, BPBio1_000643, GTPL4357, Probenecid (JP15/USP/INN), Probenecid (JP17/USP/INN), ZINC1982, DTXSID9021188, CTK6E4293, HMS500C18, KBio1_000056, KBio2_001314, KBio2_003882, KBio2_006450, KBio3_001727, AOB5799, MolPort-000-145-935, NINDS_000056, HMS1569N05, HMS1920J22, HMS2092C03, HMS2096N05, HMS2233N05, HMS3259G04, HMS3369L18, HMS3652O17, HMS3713N05, LS-33, p-(Dipropylsulfamoyl) benzoic acid, Pharmakon1600-01500502, ALBB-025846, BCP21785, HY-B0545, NSC18786, Tox21_110328, Tox21_202110, Tox21_302928, BDBM50206509, CCG-39232, KM0133, MFCD00038402, NSC-18786, NSC757292, s4022, SBB028597, STL229614, 4-Dipropylsulfamoyl-benzoic acid anion, AKOS000165123, Tox21_110328_1, AC-2023, CS-2646, DB01032, MCULE-8664946016, NC00530, NSC-757292, IDI1_000056, NCGC00016251-01, NCGC00016251-02, NCGC00016251-03, NCGC00016251-04, NCGC00016251-05, NCGC00016251-06, NCGC00016251-07, NCGC00016251-09, NCGC00016251-10, NCGC00016251-13, NCGC00023829-03, NCGC00023829-04, NCGC00023829-05, NCGC00023829-06, NCGC00023829-07, NCGC00256441-01, NCGC00259659-01, AJ-08118, AN-14383, CPD000058280, SAM002554923, ST099094, 4-(N,N-dipropylaminosulphonyl)benzoic acid, SBI-0051492.P003, KB-110510, TX-016847, 4-[(di-n-propylamino)sulphonyl]benzoic acid, 4-Dipropylsulfamoyl-benzoic acid(probenecid), AB00052080, FT-0603239, P1975, ST24043114, EN300-69677, C07372, D00475, J10155, AB00052080_15, AB00052080_16, 038P402, AE-641/01663014, I01-1905, Q-201621, SR-01000003108-2, SR-01000003108-3, BRD-K95237249-001-05-9, BRD-K95237249-001-15-8, Z53037954, Probenecid, European Pharmacopoeia (EP) Reference Standard, Probenecid, United States Pharmacopeia (USP) Reference Standard

ID: 416

InChIKey: DBEPLOCGEIEOCV-WSBQPABSSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 57363
synonyms found at PubChem are:
finasteride, 98319-26-7, Proscar, Propecia, Finastid, Prostide, Chibro-Proscar, MK-906, Finasterida, Finasteridum, Finpecia, Finasteridum [INN-Latin], Finasterida [INN-Spanish], MK 906, Andozac, UNII-57GNO57U7G, Propecia (TN), Proscar (TN), MK 0906, MK-0906, Finasteride [USAN:INN:BAN], CCRIS 7438, HSDB 6793, MK906, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide, CHEMBL710, N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide, BRN 4269024, L-652,931, Prosteride, (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, 57GNO57U7G, CHEBI:5062, (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide, 17beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androst-1-en-3-one, C23H36N2O2, N-(2-Methyl-2-propyl)-3-oxo-4-aza-5-alpha-androst-1-ene-17-beta-carboxamide, YM-152, 4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha,17beta)-, KS-1058, DSSTox_CID_625, N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-en-17beta-carboxamide, N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide, DSSTox_RID_75699, DSSTox_GSID_20625, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-dimethylethyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide, Eucoprost, Propeshia, Chibro Proscar, (4AR,4BS,6AS,7S,9AS,9BS,11AR)-4A,6A-DIMETHYL-2-OXO-2,4A,4B,5,6,6A,7,8,9,9A,9B,10,11,11A-TETRADECAHYDRO-1H-INDENO[5,4-F]QUINOLINE-7-CARBOXYLIC ACID TERT-BUTYLAMIDE, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-Butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,1, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide, SMR000466304, SR-01000759414, Finasterid (TN), Prosteride (TN), Alternova (TN), NCGC00016965-01, Finpecia (TN), CPD000466304, Finasteride [USAN:USP:INN:BAN], Appecia (TN), CAS-98319-26-7, Finalo (TN), Finara (TN), Finast (TN), Fincar (TN), Gefina (TN), Finax (TN), Finasteride (Proscar), Finasterid IVAX (TN), AC1L1MUF, Finasteride (USP/INN), Prestwick0_000717, Prestwick1_000717, Prestwick2_000717, Prestwick3_000717, MSD Brand of Finasteride, D08IWD, Lipha Brand of Finasteride, AC1Q5L2C, SCHEMBL5509, BSPBio_000933, MLS000759404, MLS001165768, MLS001424046, Finasteride (JAN/USP/INN), Merck Brand 1 of Finasteride, Merck Brand 2 of Finasteride, SPBio_002854, Proscar, Propecia, Finasteride, BPBio1_001027, GTPL6818, DTXSID3020625, DBEPLOCGEIEOCV-WSBQPABSSA-N, MolPort-002-500-272, BCPP000229, HMS1570O15, HMS2051F09, HMS2090G22, HMS2097O15, HMS2235L23, HMS3714O15, 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, ACT02599, Frosst Iberica Brand of Finasteride, ZINC3782599, Tox21_110717, Tox21_201506, Tox21_302744, AN-615, BDBM50334788, Merck Frosst Brand 1 of Finasteride, Merck Frosst Brand 2 of Finasteride, MFCD00869737, MK 609, MSD Chibropharm Brand of Finasteride, NSC741485, s1197, AKOS015894916, Tox21_110717_1, AB07586, BCP9000685, CCG-100937, CS-1767, DB01216, Finasteride, >=98% (HPLC), powder, LS-7397, NC00187, NSC-741485, Cahill May Roberts Brand of Finasteride, NCGC00093560-05, NCGC00256334-01, NCGC00259057-01, AJ-45596, AK-72879, BC200264, BR-72879, CC-28426, HY-13635, SC-12178, BCP0726000222, AB1008360, ST2419391, AB00513901, FT-0082891, Merck Sharp & Dhome Brand 2 of Finasteride, Merck Sharp & Dohme Brand 1 of Finasteride, D00321, J10122, X-2990, 32329-EP2272827A1, 32329-EP2275420A1, 32329-EP2280012A2, 32329-EP2281815A1, 32329-EP2292615A1, 32329-EP2295055A2, 32329-EP2295416A2, 32329-EP2295426A1, 32329-EP2295427A1, 32329-EP2298748A2, 32329-EP2298764A1, 32329-EP2298765A1, 32329-EP2298768A1, 32329-EP2301928A1, 32329-EP2301933A1, 32329-EP2305640A2, 32329-EP2305642A2, 32329-EP2305671A1, 32329-EP2311453A1, 32329-EP2311808A1, 32329-EP2311825A1, 32329-EP2311827A1, 32329-EP2311829A1, 32329-EP2311840A1, AB00513901-07, AB00513901-08, AB00513901_09, Finasteride, VETRANAL(TM), analytical standard, 319F267, C-34893, SR-01000759414-4, SR-01000759414-6, BRD-K01095011-001-03-5, BRD-K01095011-001-15-9, Finasteride, British Pharmacopoeia (BP) Reference Standard, Finasteride, European Pharmacopoeia (EP) Reference Standard, (17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one, Finasteride, United States Pharmacopeia (USP) Reference Standard, 17BETA-(N-TERT-BUTYLCARBAMOYL)-4-AZA-5ALPHA-ANDROST-1-EN-3-ONE, (5ALPHA,17BETA)-N-(1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE, 1,(5ALPHA)-ANDROSTAN-4-AZA-3-ONE-17BETA-(N-TERT-BUTYL-CARBOXAMIDE), 4-azaandrost-1-ene-17-carboxamide, N -(1,1-dimethylethyl)-3-oxo-,(5(alpha),17(beta))-, 4-azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5alpha, 17beta)-, 4-Azaandrost-1-ene-17-carboxamide,1-dimethylethyl)-3-oxo-, (5.alpha., 17.beta.)-, Finasteride for peak identification, European Pharmacopoeia (EP) Reference Standard, (1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-3-ene-14-carboxamide, (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-isobutyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide, (4aR,4bS,6aS,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, (4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, (4aR,6aS,11aR)-4a,6a-Dimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, (4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, (4aR,6aS,7S,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, (R)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide, 4a,6a,9a-Trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (Finasteride), 4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid tert-butylamide(Finasteride), N-tert-Butyl-3-oxo-4-aza-5|A-androst-1-en-17|A-carboxamide; N-(2-Methyl-2-propyl)-3-oxo-4-aza-5|A-androst-1-ene-17|A-carboxamide

ID: 417

InChIKey: DBPWSSGDRRHUNT-CEGNMAFCSA-N
SMILES: CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6238
synonyms found at PubChem are:
17-Hydroxyprogesterone, 17ALPHA-HYDROXYPROGESTERONE, hydroxyprogesterone, 68-96-2, 17a-Hydroxyprogesterone, Prodix, Prodox, Gestageno gador, Setaderm, Oxiprogesteronum, 17-alpha-Hydroxyprogesterone, 17-Hydroxypregn-4-ene-3,20-dione, 17alpha-Hydroxy-4-pregnene-3,20-dione, 17alpha-Hydroxy-progesterone, Hidroxiprogesterona, Hydroxyprogesteronum, Pregn-4-ene-3,20-dione, 17-hydroxy-, Gestageno, Idrossiprogesterone [DCIT], Pregn-4-ene-3,20-dione-17-ol, delta(4)-Pregnene-17alpha-ol-3,20-dione, Hydroxyprogesteronum [INN-Latin], Hidroxiprogesterona [INN-Spanish], 17-OH Progesterone, HSDB 3343, 17-Hydroxypregn-4-en-3,20-dione, Hydroxyprogesterone [INN:BAN], CHEBI:17252, 17-Hydroxyprogeoterone, UNII-21807M87J2, EINECS 200-699-4, NSC 15468, 17alpha hydroxyprogesterone, BRN 2062088, 17OHP, 17.alpha.-Hydroxyprogesterone, 604-09-1, MLS000028453, 4-Pregnen-17a-ol-3,20-dione, DBPWSSGDRRHUNT-CEGNMAFCSA-N, U 3096, 4-Pregnen-17alpha-ol-3,20-dione, (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, Delta4-Pregnen-17alpha-ol-3,20-dione, NCGC00093949-03, alpha-17Hydroxypregn-4-ene-3,20-dione, SMR000058349, 21807M87J2, DSSTox_CID_20747, DSSTox_RID_79586, DSSTox_GSID_40747, Pregn-4-ene-3,20-dione, 17-hydroxy-, (17a)-, alpha Hydroxy progesterone, Idrossiprogesterone, CAS-68-96-2, 17alpha-Hydroxypregn-4-ene-3,20-dione, (9beta)-17-Hydroxypregn-4-Ene-3,20-Dione, hydroxyprogesterone;, 3QZ, 17-alpha-Hydroxypregn-4-ene-3,20-dione, 17-hydroxy-progesterone, 17-a-Hydroxyprogesterone, Opera_ID_1812, 17|A-Hydroxyprogesterone, Hydroxyprogesterone (INN), bmse000472, bmse000598, D06WBH, Epitope ID:152220, AC1L1M3C, SCHEMBL8068, CHEMBL1062, BIDD:PXR0103, Lopac0_000565, 17.alpha.-Hydoxyprogesterone, 4-08-00-02189 (Beilstein Handbook Reference), MLS001076300, MLS002695950, 17-OHP, GTPL5104, Progesterone, 17alpha-hydroxy-, DTXSID6040747, Pregn-4-ene-3,20-dione, 17-hydroxy-, (17.alpha.)-, 17|A-oC>>u>>AEIaI feminine, CTK8F3204, Pregn-4-ene-3, 17-hydroxy-, MolPort-002-507-146, HMS2090M08, HMS2234J04, HMS3261B12, D4-Pregnen-17a-ol-3,20-dione, EBD34989, HY-B0891, NSC15468, Pregn-4-en-17a-ol-3,20-dione, ZINC5434436, Tox21_111233, Tox21_301530, Tox21_500565, ABP000341, BDBM50423511, CH0032, LMST02030161, NSC-15468, s4507, 17alpha-Hydroxyprogesterone, >=95%, 17a-Hydroxypregn-4-ene-3,20-dione, AKOS015955623, Tox21_111233_1, ACN-031972, CCG-204655, CS-4354, KS-5312, LP00565, MCULE-1412596642, 4-Pregnen-17.alpha.-ol-3,20-dione, NCGC00093949-04, NCGC00093949-05, NCGC00255425-01, NCGC00261250-01, AJ-54084, AK103604, AN-41913, CC-03833, H581, SC-46850, 17alpha-hydroxy-pregn-4-ene-3,20-dione, LS-118696, 17.alpha.-Hydroxypregna-4-ene-3,20-dione, EU-0100565, ST24021390, ST50411345, V1408, C01176, D08052, H 5752, 92478-EP2295416A2, 92478-EP2295426A1, 92478-EP2295427A1, 92478-EP2298748A2, 92478-EP2305642A2, AB00490003-08, C-20028, W-104646, 17-Hydroxypregn-4-ene-3,20-dione-, (17.alpha.)-, 7A45BEF6-ADD0-4B3E-A014-2DE930D3B67B, 17alpha-Hydroxyprogesterone, VETRANAL(TM), analytical standard, 17|A-oC>>uOEthcThorn-4-I(c)-3,20- paragraph signthornI feminine, (1S,11S,15S,2R,10R,14R)-14-acetyl-14-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7 .0.0<2,7>.0<11,15>]heptadec-6-ene, (1S,2R,10R,11S,14R,15S)-14-acetyl-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, 1050677-68-3, 17alpha-Hydroxyprogesterone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, 67085-08-9, Hydroxyprogesterone / 17a-Hydroxyprogesterone; 4-Pregnen-17a-ol-3,20-dione; 17a-Hydroxypregn-4-ene-3,20-dione

ID: 418

InChIKey: DBQGNQJBIQYHIE-GAJAGNJQSA-N
SMILES: C/C=C(\C)/C(=O)O[C@@H]1[C@@H]2C=C3[C@H](CC[C@@]4([C@H]3CC(=O)O[C@H]4C5=CC(OC5=O)O)C)[C@@](C2=O)([C@H](C1(C)C)[C@H](C(=O)OC)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 76327465
synonyms found at PubChem are:
SWIETENINE PP, CHEMBL2288852

ID: 419

InChIKey: DBUCFOVFALNEOO-HWBIYQLFSA-N
SMILES: C/C=C(/C)\C(=O)O[C@H]1CC[C@]2([C@H]3[C@@]1(O[C@@]24C[C@]5([C@@H]6CN7C[C@H](CC[C@H]7[C@@]([C@]6([C@H](C[C@]5([C@@H]4CC3)O)O)O)(C)O)C)O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5380394
synonyms found at PubChem are:
CEVADINE, veratrine, 62-59-9, Cevadin, Cevadene, Veratrine (crystallized) (VAN), EINECS 200-545-6, NSC 93767, UNII-ERQ7M6C50B, BRN 0072445, ERQ7M6C50B, Veratrine (crystallized), (Z)-4-alpha,9-Epoxycevane-3-beta,4,12,14,16-beta,17,20-heptol 3-(2-methyl-2-butenoate), Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-(2-methyl-2-butenoate), (3beta(Z),4alpha,16beta)-, Cevane-3-beta,4-beta,12,14,16-beta,17,20-heptol, 4,9-epoxy-, 3-(2-methylcrotonate), (Z)-, NSC93767, Spectrum5_000608, Spectrum5_000732, BSPBio_002258, BSPBio_003121, 4-21-00-06820 (Beilstein Handbook Reference), SCHEMBL117846, CHEMBL2163790, DTXSID4058237, ZINC8214734, 6939AF, IDI1_000856, NCGC00178282-01, NCGC00178282-02, LS-52863, UNII-08TH0Z765Z component DBUCFOVFALNEOO-HWBIYQLFSA-N, UNII-4I27BB349X component DBUCFOVFALNEOO-HWBIYQLFSA-N, Cevane-3beta,4beta,12,14,16beta,17,20-heptol, 4,9-epoxy-, 3-(2-methylcrotonate), (Z)-, 51838-64-3, Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-((2Z)-2-methyl-2-butenoate), (3beta,4alpha,16beta)-, Cevane-3beta,4beta,12,14,16beta,17,20-heptol, 4,9-epoxy-, 3-(2-methylcrotonate), (Z)- (8CI)

ID: 420

InChIKey: DBZQFUNLCALWDY-PNHWDRBUSA-N
SMILES: C1=CN=C(C2=C1N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 23190
synonyms found at PubChem are:
3-DEAZAADENOSINE, 6736-58-9, 3-deaza-adenosine, (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, UNII-037V4520IY, 3DZA, Deaza-Ado, 037V4520IY, Adenosine, 3-deaza-, 3-Deaza Adenosine, AD3, NSC167897, 9-Deazaado, Cc3Ado, DHCDA, NSC 167897, C^3Ado, 1hp0, AC1L2LUJ, D0I7TN, 4-Amino-1-(|A-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine, 3-Deazaadenosine, 3-DeazaA, BIDD:GT0703, CHEMBL202701, GTPL5115, SCHEMBL1738519, DTXSID2040941, BDBM82055, CTK8F5031, MolPort-003-941-166, BW-91Y78, MFCD00153951, ZINC18193375, AKOS024260271, CS-W014048, DB04546, HY-W013332, AJ-70456, KB-31525, CAS_6736-58-9, FT-0665514, ST24033995, J-700350, 4-amino-1-beta-d-ribofuranosyl-1h-imidazo[4,5-c]pyridine, 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine, {1H-Imidazo[4,5-c]pyridine,} 4-amino-1-.beta.-D-ribofuranosyl-, 1H-Imidazo(4,5-c)pyridin-4-amine, 1-beta-D-ribofuranosyl- (9CI), 1H-Imidazo(4,5-c)pyridine, 4-amino-1-beta-D-ribofuranosyl- (8CI), (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol, (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, (2R,3R,4S,5R)-2-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)oxolane-3,4-diol, 86583-19-9

ID: 421

InChIKey: DCMROEHBFQFVFM-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=C(C(=C(C(=C1O)Cl)O)Cl)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6710753
synonyms found at PubChem are:
ethyl 3,5-dichloro-2,4-dihydroxy-6-methylbenzoate, KBio3_002440, Spectrum3_001690, BSPBio_003220, AC1O8K17, ETHYL DICHLOROORSELLINATE, NCGC00178199-01, 27808-83-9

ID: 422

InChIKey: DCTCLIJFMDOMSY-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2

biological descriptors:

CFTR relevance: CFTR inhibitor

Category:
Influence on CFTR function inhibits CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 776409
synonyms found at PubChem are:
4'-tert-Butylflavone, BAS 01121758, AC1LFDO2, Oprea1_103916, Oprea1_776434, SCHEMBL16375370, 2-(4-tert-butylphenyl)chromen-4-one, 2-(4-tert-Butyl-phenyl)-chromen-4-one

ID: 423

InChIKey: DCTLJGWMHPGCOS-UHFFFAOYSA-N
SMILES: CC(=CCC1=C(C2=C(C3=C1OC(C=C3)(C)C)OC=C(C2=O)C4=CC=C(C=C4)O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 95168
synonyms found at PubChem are:
Osajin, 482-53-1, UNII-83R5N9X74B, CHEBI:7797, 83R5N9X74B, NSC21565, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4h,8h-benzo[1,2-b:3,4-b']dipyran-4-one, Osaiin, NSC 21565, Spectrum_000234, SpecPlus_000197, AC1L3TPU, Spectrum2_000175, Spectrum3_000225, Spectrum4_001527, Spectrum5_000034, AC1Q6NL0, Oprea1_003228, Oprea1_066678, BSPBio_001869, KBioGR_001934, KBioSS_000714, SPECTRUM201595, MLS001049118, DivK1c_006293, SCHEMBL571689, SPBio_000069, CHEMBL238188, MEGxp0_001415, ACon1_002463, CTK8D4717, KBio1_001237, KBio2_000714, KBio2_003282, KBio2_005850, KBio3_001369, MolPort-001-741-965, HMS2269P11, ZINC538127, HY-N3125, BDBM50442397, CCG-38383, LMPK12050201, MFCD00076045, NSC-21565, STK396323, Osajin, >=95% (LC/MS-ELSD), AKOS000546821, MCULE-2006868290, SDCCGMLS-0066875.P001, NCGC00095510-01, NCGC00095510-02, NCGC00095510-03, NCGC00169822-01, NCGC00169822-02, 4CN-2684, BAS 00015472, SMR000386948, ST074911, ZB014361, CS-0023313, FT-0755262, C10511, C-54675, SR-01000738732, SR-01000738732-2, BRD-K01836637-001-03-6, BRD-K01836637-001-12-7, 4H,2-b:3,4-b']dipyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-, 4H,2-b:3,4-b']dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-, 4H,8H-Benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)- (8CI), 4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-4H,8H-pyrano[2,3-f]chromen-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)-4H,8H-pyrano[2,3-f]chromen-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)-8H-pyrano[2, 3-f]chromen-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one

ID: 424

InChIKey: DCYZWGKBLADIJE-VCDNCRAOSA-N
SMILES: C[C@]12CC[C@](CC1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)(O)Cl

biological descriptors:

CFTR relevance: weak CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "Y Luo" "KA Teske" "JW Hanrahan" "D Zhang" "DY Thomas"

CID is 91430428

ID: 425

InChIKey: DDFHQXAQWZWRSQ-UHFFFAOYSA-N
SMILES: C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957470
synonyms found at PubChem are:
BU224 hydrochloride, BU 224 hydrochloride, 2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride, 187173-05-3, 205437-64-5, BU-224, SR-01000075255, EU-0100167, BU224 hydrochloride, solid, SCHEMBL2492973, CHEMBL1255832, CTK8E6980, MolPort-003-940-410, Tox21_500167, AKOS024458619, API0008359, CCG-221471, LP00167, NCGC00093651-01, NCGC00260852-01, KB-222157, RT-011826, J-012044, SR-01000075255-1, SR-01000075255-3, 2-(4,5-Dihydroimidazol-2-yl)-quinoline hydrochloride, 2-(4,5-dihydro-1H-imidazol-2-yl)quinoline hydrochloride, 2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride (1:1)

ID: 426

InChIKey: DDFWVWUTJUSDMK-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C2=NNC(=O)C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 13040300
synonyms found at PubChem are:
66076-78-6, 2,4-DIHYDRO-5-(4-METHYLPHENYL)-3H-PYRAZOL-3-ONE, CTK5C3475, DTXSID20516037, AKOS004121316, ZINC100127696, 3-(p-tolyl)-1,4-dihydropyrazol-5-one, AN-38552, KB-164773, 076D786, 3H-Pyrazol-3-one,2,4-dihydro-5-(4-methylphenyl)-

ID: 427

InChIKey: DDMVHGULHRJOEC-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1N2CCNCC2.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9899402
synonyms found at PubChem are:
1-(2-Methoxyphenyl)piperazine hydrochloride, 5464-78-8, Ompp, UNII-3XQ74IHW73, 1-(2-Methoxyphenyl)piperazine HCl, 1-(2-methoxyphenyl)-pepipazine HCl, N-(2-Methoxyphenyl)piperazine hydrochloride, 3XQ74IHW73, NCGC00094390-01, 1(2-Methoxyphenyl)piperazine hydrochloride, 1-(2-methoxylphenyl)piperazine hydrochloride, DSSTox_CID_30037, DSSTox_RID_81139, DSSTox_GSID_51440, Piperazine, 1-(2-methoxyphenyl)-, monohydrochloride, W-105612, CAS-5464-78-8, 1-[2-methoxyphenyl)piperazine hydrochloride, MLS001056761, EINECS 226-762-6, 2-MPP hydrochloride, PubChem15274, 1-(2-Methoxyphenyl)piperazinium chloride, KSC269I3N, ARONIS25347, SCHEMBL246416, SPECTRUM2300348, CHEMBL1256365, DTXSID5051440, CTK1G9436, DDMVHGULHRJOEC-UHFFFAOYSA-N, MolPort-001-029-521, EBD10695, NSC28709, 1- pound 2-methoxyphenyl)piperazine, 1-(2-methoxyphenyl) piperazine hcl, Tox21_111273, Tox21_501122, ANW-32140, CCG-39603, MFCD00012762, NSC-28709, SBB003293, 1-(2-methoxy phenyl) piperazine hcl, 1-(2-methoxyphenyl)-piperazine, hcl, o-methoxyphenylpiperazine hydrochloride, 2-methoxyphenylpiperazine hydrochloride, AKOS003745112, Tox21_111273_1, CHM0117278, LF-0552, LP01122, MCULE-2187458555, o-methoxyphenyl piperazine hydrochloride, RTC-060898, TRA0049459, KS-0000477S, (2-methoxyphenyl)piperazine hydrochloride, 1-methoxy-2-piperazinylbenzene, chloride, 2-methoxy-1-piperazinylbenzene, chloride, NCGC00015906-04, NCGC00094390-02, NCGC00094390-03, NCGC00261807-01, AC-19721, AK-47281, BR-47281, KB-63864, SC-05244, SMR000326725, 1-[2-methoxyphenyl)piperazin hydrochloride, 1-[2-methoxyphenyl)piperizine hydrochloride, AB0010592, DB-018450, KB-213227, KB-213228, TC-060898, TL8003579, 1-(2'-methoxyphenyl)piperazine hydrochloride, 1-(2-methoxyphenyl) piperazine hydrochloride, 1-(2-methoxyphenyl)-piperazine hydrochloride, AM20060668, EU-0101122, FT-0605843, S-008, ST24026849, ST45054141, 1-(2-methoxy-phenyl)-piperazine hydrochloride, 1-(2-methoxyphenyl)piperazine monohydrochloride, M-7254, 1-(2-methoxylphenyl)piperazine monohydrochloride, 1-(2-methoxyphenyl)piperazine hydrochloride salt, 1-(2-Methoxyphenyl)piperazine hydrochloride, 97%, SR-01000075575, SR-01000075575-1, 1-(2-Methoxyphenyl)piperazine hydrochloride, 97% 25g, F0268-2979, AKOS016373576

ID: 428

InChIKey: DDNCQMVWWZOMLN-IRLDBZIGSA-N
SMILES: CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 443955
synonyms found at PubChem are:
vinpocetine, 42971-09-5, Cavinton, Ceractin, Apovincaminic acid ethyl ester, Ethyl apovincamin-22-oate, TCV-3B, Ethyl (+)-apovincaminate, Vinpocetinum, Bravinton, Vinpocetinum [INN-Latin], cis-Apovincaminic acid ethyl ester, RGH 4405, RGH-4405, (+)-Apovincaminic acid ethyl ester, Ethyl (+)-cis-apovincaminate, Apovincaminate d'ethyle, (+)-cis-Apovincaminic acid ethyl ester, Apovincaminate d'ethyle [French], Ultra-Vinca, AY 27,255, UNII-543512OBTC, 3-alpha,16-alpha-Apovincaminic acid ethyl ester, Vinpocetine [USAN:INN:JAN], Eburnamenine-14-carboxylic acid ethyl ester, Ethyl apovincaminate, EINECS 256-028-0, TCV 3B, BRN 0900803, CHEMBL71752, MLS000069635, Vinpocetine (JAN/USAN/INN), Vinpocetine-ethyl apovincaminate, ethyl apovincaminate, (3alpha,16alpha)-isomer, 543512OBTC, NCGC00018204-09, AY 27255, SMR000058241, Eburnamenine-14-carboxylic acid, ethyl ester, (3alpha,16alpha)-, DSSTox_CID_3740, V 6383, DSSTox_RID_77176, DSSTox_GSID_23740, Vinporal, ethyl (3alpha,16alpha)-eburnamenine-14-carboxylate, C22H26N2O2, (3alpha, 16alpha)-Eburnamenine-14-carboxylic acid ethyl ester, Eburnamenine-14-carboxylic acid, ethyl ester, (3-alpha,16-alpha)-, (41S,13aS)-ethyl 13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate, 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic acid deriv., SR-01000075633, Vinpocetin, Intelectol (TN), NCGC00016854-03, Cavinton (TN), Vinpocetine [USAN:INN:BAN:JAN], Prestwick_963, Vinpocetine 20mg, CAS-42971-09-5, Spectrum_001400, Vinpocetine (Cavinton), SpecPlus_000327, AC1L9FGV, Opera_ID_1325, Prestwick0_000268, Prestwick1_000268, Prestwick2_000268, Prestwick3_000268, Spectrum2_001529, Spectrum3_000961, Spectrum4_001075, Spectrum5_000966, D06BCB, ethyl apovincaminate tartrate, (3|A,16|A)-Eburnamenine-14-carboxylic acid ethyl ester, Ethyl(+)-cis-apovincaminate, Lopac0_001257, SCHEMBL50081, BSPBio_000116, BSPBio_002561, KBioGR_001430, KBioSS_001880, MLS001076294, ARONIS24464, DivK1c_006423, SPECTRUM1503115, V6383_SIGMA, Vinpocetine, >=98%, solid, SPBio_001318, SPBio_002335, BPBio1_000128, cid_443955, GTPL5285, Vinpocetine, analytical standard, DTXSID5023740, REGID_for_CID_443955, CHEBI:32297, KBio1_001367, KBio2_001880, KBio2_004448, KBio2_007016, KBio3_001781, DDNCQMVWWZOMLN-IRLDBZIGSA-N, MolPort-003-666-450, HMS1568F18, HMS1922G05, HMS2090J22, HMS2092L06, HMS2095F18, HMS3263L16, HMS3402D12, HMS3712F18, Pharmakon1600-01503115, BCP04123, Tox21_110648, Tox21_110839, Tox21_501257, BDBM50059033, CCG-39307, MFCD00211233, NSC760093, PD-185, s2110, ZINC19796031, AKOS015896480, Tox21_110648_1, 3A,16A-Apovincaminic acid ethyl ester, CS-0545, DB12131, LP01257, NSC-760093, RP18037, Vinpocetine 1.0 mg/ml in Acetonitrile, (3S,16S)-apovincaminic acid ethylester, NCGC00018204-05, NCGC00018204-06, NCGC00018204-07, NCGC00018204-08, NCGC00018204-10, NCGC00018204-11, NCGC00018204-13, NCGC00021727-04, NCGC00021727-05, NCGC00021727-06, NCGC00021727-07, NCGC00168782-01, NCGC00261942-01, NCGC00263865-01, AC-22612, AS-13868, AY-27255, CC-35596, HY-13295, KB-81447, LS-63711, SC-18612, ST056350, AB2000514, AY-27,255, Eburnamenine-14-carboxylic acid ethyl ester;, EU-0101257, D01371, J10479, W-5089, AB00052317_02, 971V095, C-20627, SR-01000000118, I06-1883, SR-01000000118-3, SR-01000075633-1, SR-01000075633-3, SR-01000075633-4, W-202748, BRD-K53318339-001-05-8, (3?,16?)-Eburnamenine-14-carboxylic acid ethyl ester, Vinpocetine, European Pharmacopoeia (EP) Reference Standard, (3alpha,16alpha)-Eburnamenine-14-carboxylic acid ethyl ester, Vinpocetine, United States Pharmacopeia (USP) Reference Standard, (11aS,11bS)-11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester, (3aS,11bS)-3a-ethyl-1,2,3,3a,10,11b-hexahydro-11H-5a,11a-diaza-benzo[cd]fluoranthene-5-carboxylic acid ethyl ester, 115986-87-3, 11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid 2-nitrooxy-ethyl ester(Vinpocetine), 80038-06-8, ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0^{2,7}.0^{8,18}.0^{15,19}]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate, ethyl (41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate

ID: 429

InChIKey: DDOQBQRIEWHWBT-UHFFFAOYSA-N
SMILES: C(CP(=O)(O)O)C(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2207
synonyms found at PubChem are:
2-amino-4-phosphonobutanoic acid, 6323-99-5, 2-Amino-4-phosphonobutyric acid, DL-AP4, DL-2-Amino-4-phosphonobutyric acid, 20263-07-4, NSC30079, NSC 30079, Butanoic acid, 2-amino-4-phosphono-, BRN 5255932, (+/-)-2-Amino-4-phosphonobutyric acid, CHEMBL285843, BUTYRIC ACID, 2-AMINO-4-PHOSPHONO-, 2-Amino-4-phosphono-butyric acid, IN1534, L-2-amino-4-phosphonobutyrate, Abu(P), L-AP4 cpd, butyric, SR-01000075414, NSC-30079, L-2-amino-4-phosphobutyric acid, L-2-amino-4-phosphonobutanoic acid, AC1Q6RPJ, 4-Amino Phosphonobutyrate, D00IGI, AC1L1D5X, 2 APB, Lopac0_000064, SCHEMBL56139, L -AP4, CTK5B8255, ( inverted question mark)-AP-4, DDOQBQRIEWHWBT-UHFFFAOYSA-N, MolPort-002-513-394, HMS3260M09, KS-000024GC, Tox21_500064, ( inverted exclamation markA)-AP-4, BDBM50004051, BN0082, MFCD00013999, NSC354086, PDSP1_000818, PDSP2_000805, (y)-2-Amino-4-phosphonobutyric acid, (?)-2-Amino-4-phosphonobutyric acid, AKOS015892998, DL-2-Amino-4-phosphono-butanoic acid, CCG-204159, DL-0710, FCH1114914, LP00064, NSC-354086, ACM20263074, NCGC00015041-03, NCGC00015041-04, NCGC00015041-05, NCGC00015041-06, NCGC00024466-02, NCGC00024466-03, NCGC00024466-04, NCGC00260749-01, 2-Amino-4-phosphono-butyric acid (AP4), AM807295, LS-47843, NCI60_002523, OR311226, (+/-)-AP-4, DL-2-Amino-4-phosphonobutanoic acid (AP4), EU-0100064, FT-0625388, Butanoic acid, 2-amino-4-phosphono- (9CI), L -(+)-2-Amino-4-phosphono- butanoic acid, (+/-)-2-Amino-4-phosphonobutyric acid, solid, L-(+)-2-AMINO-4-PHOSPHONO-BUTYRIC ACID, (+/-)-2-AMINO-4-PHOSPHONO-BUTYRIC ACID, C-51648, GlcN-6-P synthase inhibitor, 1 (racemic mixture), L000344, I04-1589, J-013164, SR-01000075414-1, SR-01000075414-3, ( inverted question mark)-2-Amino-4-phosphonobutyric acid

ID: 430

InChIKey: DDRJAANPRJIHGJ-UHFFFAOYSA-N
SMILES: CN1CC(=O)N=C1N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 588
synonyms found at PubChem are:
creatinine, 60-27-5, 2-Imino-1-methylimidazolidin-4-one, 1-Methylglycocyamidine, 1-Methylhydantoin-2-imide, Creatinine,heated, 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-, 2-amino-1-methylimidazolin-4-one, Kreatinin, UNII-AYI8EX34EU, 2-Imino-N-methylhydantoin, Creatine anhydride, Creatinine [NF], AI3-15321, EINECS 200-466-7, NSC 13123, AYI8EX34EU, 2-Amino-1-methyl-2-imidazolin-4-one, 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one, Creatinine (VAN) (8CI), CHEBI:16737, Creatinine (NF), DDRJAANPRJIHGJ-UHFFFAOYSA-N, 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, NSC13123, 2-amino-3-methyl-4H-imidazol-5-one, NCGC00095762-01, 2-Amino-1-Methyl-4-Imidazolidinone, DSSTox_CID_25987, DSSTox_RID_81274, DSSTox_GSID_45987, 4H-Imidazol-4-one, 2-imino-1,5-dihydro-1-methyl-, krebiozen, CAS-60-27-5, 82016-55-5, 2-Amino-1-methyl-1,5-dihydroimidazol-4-one, creatinina, Creatinine (VAN), Spectrum_000429, Spectrum2_000764, Spectrum3_001717, Spectrum4_001806, Spectrum5_000511, bmse000155, bmse000789, bmse001001, EC 200-466-7, AC1L19KD, AC1Q3ZL5, Creatinine, 98% 10g, SCHEMBL16295, BSPBio_003334, KBioGR_002415, KBioSS_000909, MLS001306430, CHEMBL65567, DivK1c_000351, SPECTRUM1600300, SPBio_000808, Creatinine, anhydrous, >=98%, DTXSID8045987, CTK5E9313, HMS501B13, KBio1_000351, KBio2_000909, KBio2_003477, KBio2_006045, KBio3_002554, MolPort-001-779-735, MolPort-003-803-357, NINDS_000351, 1-methyl-2-amino-imidazol-4-one, Creatinine, 98.5-102.0%, HMS2233P20, HMS3372L11, Pharmakon1600-01600300, ZINC967189, HY-B0504, KS-00000DF8, 2-imino-1-methyl-4-imidazolidinone, Tox21_111516, BBL009279, CCG-40153, KM0389, MFCD00059730, NSC-13123, NSC760435, s3102, STK530885, STL268897, 2-Imino-1-methyl-imidazolidin-4-one, AKOS000121140, AKOS005458367, Tox21_111516_1, 2-Imino-1-methyl-4-imidazolidinone #, Creatinine, NIST(R) SRM(R) 914a, CS-2705, DB11846, MCULE-8832153777, NSC-760435, RP19101, SDCCGMLS-0066864.P001, IDI1_000351, NCGC00095762-02, NCGC00095762-04, NCGC00247664-01, 4H-Imidazol-4-one,5-dihydro-1-methyl-, AJ-24426, AN-23634, AS-12671, KB-49127, SC-16445, SMR000718791, ZB015360, AB0012307, AB1002711, LS-168722, FT-0082659, FT-0624087, ST24028044, 2-amino-1-methyl-1,5-dihydro-imidazol-4-one, C00791, D03600, 92630-EP2277858A1, 92630-EP2292227A2, 92630-EP2295053A1, 92630-EP2305653A1, AB00052404_03, AB00052404_04, 059C730, 2-amino-1-methyl-4,5-dihydro-1H-imidazol-4-one, 2-amino-4,5-dihydro-1-methyl-1H-imidazol-4-one, 2-Imino-1,5-dihydro-1-methyl-4H-imidazol-4-one, SR-01000837526, S14-1090, SR-01000837526-3, W-203248, F0001-1578, C5CF605C-9352-48F2-A5A4-561B97D42C30, Creatinine, United States Pharmacopeia (USP) Reference Standard, 2-Amino-1-Methyl-4-Imidazolidinone;2-Imino-1-methylimidazolidin-4-one, Creatinine, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8, 15231-31-9, 2-Amino-1-methyl-2-imidazolin-4-one; 2-Imino-1-methylimidazolidin-4-one; 2-Imino-N-methylhydantoin, 45514-66-7, Creatinine solution, 2.0 mg/mL in methanol: water (1:1), certified reference material, ampule of 1 mL

ID: 431

InChIKey: DDSFKIFGAPZBSR-UHFFFAOYSA-N
SMILES: CC(=O)OC1=CC=CC=C1C(=O)OC2=CC=CC=C2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10745
synonyms found at PubChem are:
530-75-6, 2-((2-Acetoxybenzoyl)oxy)benzoic acid, ACETYLSALICYLSALICYLIC ACID, ACETYLSALICYLSALICYIC ACID, Acesalum, Diplosal Acetate, UNII-VBE72MCP5L, 2-Carboxyphenyl 2-(acetyloxy)benzoate, DIPLOSALSALATE, CCRIS 1740, Benzoic acid, 2-(acetyloxy)-, 2-carboxyphenyl ester, 2-Carboxyphenyl o-acetylsalicylate, EINECS 208-493-6, Salicylacetylsalicylic Acid, VBE72MCP5L, 2-(2-acetyloxybenzoyl)oxybenzoic acid, MLS002154199, DDSFKIFGAPZBSR-UHFFFAOYSA-N, SMR001233486, Prestwick_544, Diplosalacetat, Spectrum_001708, SpecPlus_000894, AC1L1VUW, Prestwick0_000098, Prestwick1_000098, Prestwick2_000098, Prestwick3_000098, Spectrum2_001664, Spectrum3_000725, Spectrum4_001118, Spectrum5_001849, ASPIRIN IMPURITY D, 2-(Acetyloxy)benzoic Acid 2-Carboxyphenyl Ester, SCHEMBL25398, BSPBio_000056, BSPBio_002250, KBioGR_001596, KBioSS_002188, cid_10745, DivK1c_006990, SPECTRUM1504209, SPBio_001847, SPBio_001995, BPBio1_000062, CHEMBL350343, ZINC2063, DTXSID5074977, BDBM66982, CHEBI:94629, KBio1_001934, KBio2_002188, KBio2_004756, KBio2_007324, KBio3_001470, 2-HYDROXYBENZOIC ACID ACETATE 2-CARBOXYPHENYL ESTER, ACETYSALICYLSALICYCLIC ACID, MolPort-003-666-541, HMS1568C18, HMS2095C18, HMS2231N10, HMS3372D03, HMS3712C18, BCP07875, 2-(2-acetoxybenzoyl)oxybenzoic acid, CCG-39089, STL193282, 2-((2-Acetoxybenzoyl)oxy)benzoicacid, ACETYLSALICYLIC ACID IMPURITY C, ACETYSALICYCLIC ACID IMPURITY C, AKOS016010380, AB03877, DS-2808, MCULE-7141811875, MP-1850, VZ31212, ACETYLSALICYLSALICYLIC ACID IMP D, KS-00000I06, 2-[2-(acetyloxy)benzoyloxy]benzoic acid, NCGC00016489-01, NCGC00016489-02, NCGC00095332-01, AJ-08130, AK116479, CAS-530-75-6, SC-54875, 2-(2-ACETOXYBENZOYLOXY)BENZOIC ACID, 2-{[2-(acetyloxy)benzoyl]oxy}benzoic acid, AX8016267, LS-175414, 2-(2-acetyloxyphenyl)carbonyloxybenzoic acid, 2-(2-acetyloxyphenylcarbonyloxy)benzoic acid, 4CH-008841, AB00053270, FT-0621819, ST24027405, ST50826140, Z4833, 2-([2-(Acetyloxy)benzoyl]oxy)benzoic acid #, 2-[(2-acetyloxyphenyl)-oxomethoxy]benzoic acid, C-18743, SR-01000841191, 2-({[2-(acetyloxy)phenyl]carbonyl}oxy)benzoic acid, 2-(2-methylcarbonyloxyphenylcarbonyloxy)benzoic acid, SR-01000841191-2, BRD-K46585355-001-05-1, BRD-K46585355-001-09-3, 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic Acid (Acetylsalicylsalicylic Acid)

ID: 432

InChIKey: DDUHZTYCFQRHIY-RBHXEPJQSA-N
SMILES: C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441140
synonyms found at PubChem are:
griseofulvin, (+)-Griseofulvin, 126-07-8, Amudane, Fulvicin, Grisactin, Grisefuline, Griseofulvina, Griseofulvinum, Griseofulvine, Grizeofulvin, Grifulvin, Grisofulvin, Grisovin, Spirofulvin, Fulcin, Grysio, Lamoryl, Likuden, Poncyl, Curling factor, Grifulvin V, Delmofulvina, Fulvistatin, Griscofulvin, Fulcine, Fulvina, Fulvinil, Fungivin, Greosin, Gresfeed, Grifulin, Griseomix, Grisetin, Guservin, Murfulvin, Gricin, Gris-PEG, Griseo, Grisactin Ultra, Neo-Fulcin, Biogrisin-FP, Fulvican grisactin, Griseofulvin forte, Griseofulvin-forte, Fulvicin P/G, Fulvicin-P/G, Fulvicin-U/F, Xuanjing, Griseofulvine [INN-French], Griseofulvinum [INN-Latin], Griseofulvina [INN-Spanish], GRISEOFULVIN, MICROCRYSTALLINE, Fulvidex (Veterinary), Fulvicin-U-F, ULTRAGRIS-165, ULTRAGRIS-330, USAF SC-2, Fulvicin-U/F (Veterinary), GRISEOFULVIN, ULTRAMICROCRYSTALLINE, Fulvicin Bolus (Veterinary), FULVICIN P/G 165, FULVICIN P/G 330, Caswell No. 471B, Griseostatin, Likunden, Grise ostatin, Sporostatin xan, curling fact or, Grisovin FP, Fulvicin U/F, UNII-32HRV3E3D5, C17H17ClO6, CCRIS 320, HSDB 1722, GRISEOFULVIN, ULTRAMICROSIZE, Griseofulvin [USAN:INN:BAN:JAN], EINECS 204-767-4, NSC 34533, EPA Pesticide Chemical Code 471400, Griseofulvin and Alpha-IFN, BRN 0095226, GRISEOFULVIN, MICROSIZE, AI3-51015, 32HRV3E3D5, 7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione, CHEBI:27779, (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione, NCGC00091120-01, CPD000718755, DSSTox_CID_674, 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy-6'-methylcyclohex-2'-en-4'-one), DSSTox_RID_75725, DSSTox_GSID_20674, (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione, (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (2S-trans)-, Fulvicin Bolus, Fulvidex, interacts with polymerized microtubules and associated proteins, FulvicinUF, Grisactin V, GrisPEG, Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-, Fulvicin U F, Gris PEG, (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione, SMR000718755, Griseofulvin microsize, SR-05000001535, grisefulin, fulvicin UF, Griseofulvin,(S), Griseofulvin [USP:INN:BAN:JAN], Grisovin (TN), (1'S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione, (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methyl-spiro[benzofuran-2,4'-cyclohex-2-ene]-1',3-dione, (2S-trans)-7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, Prestwick_247, Grisactin V (TN), Gris-peg (TN), PubChem17619, Spectrum_000816, SpecPlus_000336, AC1L9AMF, Prestwick3_000226, Spectrum2_000213, Spectrum3_000161, Spectrum4_000927, Spectrum5_000648, Griseofulvin [USP:INN], CHEMBL562, D0C1SF, SCHEMBL21988, BSPBio_000271, BSPBio_001621, KBioGR_001454, KBioSS_001296, SPECTRUM200046, 5-18-05-00150 (Beilstein Handbook Reference), MLS001304062, MLS002152905, MLS002154239, BIDD:GT0024, DivK1c_000154, DivK1c_006432, Griseofulvin (JAN/USP/INN), SPBio_000225, AC1Q496M, BPBio1_000299, MEGxm0_000184, DTXSID8020674, ACon0_000953, ACon1_001843, BDBM31775, Fulvicin-U/F Powder and Tablets, HMS500H16, KBio1_000154, KBio1_001376, KBio2_001296, KBio2_003864, KBio2_006432, KBio3_001121, DDUHZTYCFQRHIY-RBHXEPJQSA-N, MolPort-001-739-410, NINDS_000154, HMS1923E09, HMS2091A03, HMS2095N13, HMS2235F13, HMS3259D05, HMS3712N13, Pharmakon1600-00200046, ZINC622123, Tox21_111087, Tox21_202235, Tox21_303005, CCG-38416, LMPK13060001, LS-702, MFCD00082343, NSC755822, s4071, AKOS015896380, Tox21_111087_1, CS-3426, DB00400, MCULE-1983595404, NC00616, NE11198, NSC-755822, SDCCGMLS-0066450.P001, IDI1_000154, NCGC00091120-02, NCGC00091120-03, NCGC00091120-04, NCGC00091120-05, NCGC00091120-06, NCGC00091120-07, NCGC00091120-08, NCGC00091120-09, NCGC00091120-13, NCGC00256353-01, NCGC00259784-01, (1'S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, (1'S-trans)- 7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-cyclohex-2'-ene)-3,4'-dione, AN-22970, AS-13736, HY-17583, KB-62489, M542, SAM002548953, SAM002589940, SC-13647, AB0015270, AB1009300, NP-002466, FT-0082593, FT-0603329, G0384, EN300-52615, BIM-0051396.0001, C06686, D00209, J10209, AB00052005_07, Griseofulvin, VETRANAL(TM), analytical standard, SR-01000837512, Griseofulvin, Antibiotic for Culture Media Use Only, Q-201178, SR-01000837512-2, SR-05000001535-1, SR-05000001535-3, SR-05000001535-4, BRD-K08273968-001-05-9, BRD-K08273968-001-09-1, BRD-K08273968-001-19-0, Z1258578352, Griseofulvin, from Penicillium griseofulvum, 97.0-102.0%, Griseofulvin, European Pharmacopoeia (EP) Reference Standard, Griseofulvin, United States Pharmacopeia (USP) Reference Standard, 7-chloro-2',4,6-trimethoxy-6'-beta-spiro[benzofuran-2(3H),1'-(2)cyclohexene-3,4'-dione], 7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexene]-3,4'-dione, Griseofulvin Permeability Diameter, United States Pharmacopeia (USP) Reference Standard, Griseofulvin, Pharmaceutical Secondary Standard; Certified Reference Material, (2S)-trans-7-Chloro-2 inverted exclamation marka,4,6-trimethoxy-6 inverted exclamation marka-methylspiro(benzofuran-2[3H],1 inverted exclamation marka-[2]cyclohexene)-3,4 inverted exclamation marka-dione; Griseofulvin, (2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione, (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione, (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methylbenzofuran-2-spiro-1'-cyclohex-2'-ene-3,4'-dione, 11103-62-1, 24659-79-8, 2884-22-2, 3426-54-8, 7-chloro-2',4,6-trimethoxy-6'-beta-spiro[benzofuran-2(3H ),1'-(2)cyclohexene-3,4'-dione], 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1',- [2]cyclohexene]-3,4'-dione, 7-chloro-4,6-dimethox ycoumaran-3-one-2-spiro-1'-(2'-methoxy)-6'-methylcyclohex-2'-en-4'-one, 7-chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy)-6'-methylcyclohex-2'-en-4'-one, 7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1-(2'-methoxy-6'-methyl cyclohex-2'-en-4'-one), 8027-03-0, 8055-10-5, Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy- 6'-beta-methyl-, Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-beta-methyl-, Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2'4,6-trimethoxy-6'-beta-methyl-

ID: 433

InChIKey: DDXORDQKGIZAME-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 68589
synonyms found at PubChem are:
Econazole nitrate, 24169-02-6, Ifenec, Epi-pevaryl, Gyno-pevaryl, Econazole nitrate salt, Pevaryl, 68797-31-9, (+-)-Econazole nitrate, Spectazole, Econazolum Nitrate, Gyno-Pevaryl 150, Econazole (nitrate), ECONAZOL NITRATE, EcoNail, NSC 243115, GYNORYL, CCRIS 6031, R 14827, EINECS 246-053-5, Econazole nitrate (Spectazole), MLS000028626, 1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate, R 14,827, SMR000058732, Spectazole (TN), DSSTox_CID_5226, Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-, mononitrate, 1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid, DSSTox_RID_77708, DSSTox_GSID_25226, 1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazolium nitrate, 1-[2-([4-Chlorophenyl]methoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate, 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate, 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, nitrate, Econazole mononitrate, NSC243115, UNII-K60125XWSJ, SR-01000003142, NCGC00018258-03, UNII-954U9X7U4N, K60125XWSJ, 954U9X7U4N, Micogin, Ecoza, C18H15Cl3N2O.HNO3, Econazole nitrate [USAN:USP], Econazole/SEPA, 1-(2-((4-chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-(2-((4-CHLOROPHENYL)METHOXY)-2-(2,4-DICHLOROPHENYL)ETHYL)IMIDAZOLE NITRATE, 1-(2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate, 1-[2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole nitrate, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid, 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate, Prestwick_191, Econazole nitrate [USAN:BAN:JAN], EINECS 272-295-6, EINECS 277-281-3, EINECS 277-282-9, econazole; nitric acid, Econazole nitrate [USAN:USP:BAN:JAN], Econazole Nitrate,(S), ECOSTATIN NITRATE, Opera_ID_1393, Econazole nitrate, (R)-, Econazole nitrate, (S)-, D0J1CL, AC1L2A1Y, CAS-24169-02-6, SCHEMBL36213, MLS001076561, MLS002222182, MLS002415728, Econazole nitrate (JAN/USP), SPECTRUM1501185, REGID_for_CID_68589, C18H16Cl3N3O4, C18H16Cl2N2O.HNO3, CHEMBL1201049, DTXSID6025226, CTK2F3087, HMS500F15, KS-00000ZUY, MolPort-003-666-381, HMS1568N10, HMS1921P03, HMS2092L03, HMS2095N10, HMS2235C19, HMS3656C14, HMS3712N10, Pharmakon1600-01501185, 27220-47-9 (Parent), BCP12552, HY-B0453, Tox21_110852, Tox21_200771, Tox21_303391, CCG-38966, MFCD00058160, NSC757882, s2535, AKOS015895218, Tox21_110852_1, AB02338, AC-1113, API0002519, API0024947, CS-2564, LS-1039, NSC-243115, NSC-757882, (+)-1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazolium nitrate, (-)-1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazolium nitrate, NCGC00018258-10, NCGC00089813-02, NCGC00094926-01, NCGC00094926-02, NCGC00094926-03, NCGC00094926-04, NCGC00257500-01, NCGC00258325-01, 73094-38-9, 73094-40-3, AK163676, AN-15271, AN-51032, AS-13263, BC203888, CPD000058732, H755, SAM002554898, SC-75524, SQ-13050, AB0013234, AB2000632, AX8041492, LS-176697, E0957, FT-0625644, FT-0630510, ST24046673, VU0239797-5, C08069, D00881, Ecostatin; Epi-Pevaryl; Gyno-Pevaryl; Gynoryl, 1H-Imidazole,4-dichlorophenyl]ethyl)-, nitrate, A836253, I06-189, 1H-Imidazole,4-dichlorophenyl)ethyl]-, mononitrate, I06-0189, I06-1860, J-015380, SR-01000003142-2, SR-01000003142-3, 1-[2-(4-Chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Nitrate, Imidazole,4-dichloro-.beta.-[(p-chlorobenzyl)oxy]phenethyl]-, mononitrate, (+-)-1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-imidazole mononitrate, (1)-1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazolium nitrate, 1-[2-(4-CHLOROPHENYLMETHOXY)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE, Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-, mononitrate (8CI), 1-(2-((4-CHLOROPHENYL)METHOXY)-2-(2,4-DICHLOROPHENYL)-ETHYL)-1H-IMIDAZOLE MONONITRATE, 1-(2-[(4-CHLOROPHENYL)METHOXY]-2-[2,4-DICHLOROPHENYL]ETHYL)-1H-IMIDAZOLE NITRATE SALT, 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate (9CI), 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate, (+-)-

ID: 434

InChIKey: DECIPOUIJURFOJ-UHFFFAOYSA-N
SMILES: CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3293
synonyms found at PubChem are:
ethoxyquin, 91-53-2, 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline, Ethoxyquine, Santoquin, Santoquine, Niflex, Antioxidant EC, Santoflex A, Santoflex AW, Stop-Scald, Dawe's nutrigard, Nix-Scald, Nocrack AW, Quinol ED, Permanax 103, Aries Antox, Niflex D, Antage AW, Nocrac AW, Alterungsschutzmittel EC, (-)-Normetazocine, Ethoxychin, Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-, Usaf B-24, Amea 100, Ethoxyquin [ISO], Santoquine (VAN), 1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline, Ethoxychin [Czech], Caswell No. 427D, 1,2-Dihydro-2,2,4-trimethyl-6-ethoxyquinoline, 2,2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline, 6-ethoxy-2,2,4-trimethyl-1H-quinoline, NSC-6795, UNII-9T1410R4OR, CCRIS 2513, HSDB 400, EINECS 202-075-7, EMQ, EQ, EPA Pesticide Chemical Code 055501, AI3-17715, CHEBI:77323, DECIPOUIJURFOJ-UHFFFAOYSA-N, 9T1410R4OR, 6-(ethyloxy)-2,2,4-trimethyl-1,2-dihydroquinoline, CAS-91-53-2, NCGC00016348-02, E324, DSSTox_CID_582, DSSTox_RID_75672, DSSTox_GSID_20582, 16603-67-1, W-100306, Ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolinyl ether, 6-ETMDQ, Polyflex, Santoflex, SantoquinEQ, Ethoxy quinoline, Prestwick_1064, Spectrum_001214, AC1L1FLT, Prestwick0_000765, Prestwick1_000765, Prestwick2_000765, Prestwick3_000765, Spectrum2_001384, Spectrum3_001423, Spectrum4_000404, Spectrum5_001530, SCHEMBL21601, BSPBio_000810, BSPBio_003126, KBioGR_000668, KBioSS_001694, MLS001055488, BIDD:GT0822, DivK1c_000183, SPECTRUM1500998, SPBio_001368, SPBio_002749, BPBio1_000892, CHEMBL172064, DTXSID9020582, CTK8F1416, HMS500J05, KBio1_000183, KBio2_001694, KBio2_004262, KBio2_006830, KBio3_002346, KS-00000LXG, NSC6795, MolPort-002-720-734, NINDS_000183, HMS1570I12, HMS1923K03, HMS2097I12, HMS3714I12, 1,2,4-trimethyl-6-ethoxyquinoline, HY-B1425, NSC 6795, Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-, homopolymer, ZERO/001992, ZINC3872521, 6-Ethoxy-1,2,4-trimethylquinoline, Tox21_110388, Tox21_201336, Tox21_300328, CCG-39002, Ethoxyquin, >=75% (capillary GC), SBB012680, STK772149, AKOS000121441, CS-8200, LS-1921, MCULE-2419717294, IDI1_000183, NCGC00016348-01, NCGC00016348-03, NCGC00016348-04, NCGC00016348-05, NCGC00016348-06, NCGC00016348-07, NCGC00016348-08, NCGC00016348-09, NCGC00090792-01, NCGC00090792-02, NCGC00090792-03, NCGC00090792-04, NCGC00090792-05, NCGC00254395-01, NCGC00258888-01, 63301-91-7, AC-11742, AJ-46362, AK116687, AN-24213, AS-14741, BC203326, CC-27555, KB-73940, M384, SMR000686069, BC4134527, Ethoxyquin, Vetec(TM) reagent grade, 75%, ST2418944, ST4083901, TR-028835, WLN: T66 BM CHJ C1 C1 E1 HO2, E 324, E0237, FT-0621107, FT-0673108, 2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline, 6-Ethoxy-2,4-trimethyl-1,2-dihydroquinoline, Ethoxyquin, PESTANAL(R), analytical standard, 2,2, 4-Trimethyl-6-ethoxy-1,2-dihydroquinoline, 6-Ethoxy-1, 2-dihydro-2,2,4-trimethylquinoline, 6-Ethoxy-1,2-dihydro-2,2,4-trimethyl-Quinoline, 6-Ethoxy-2,2,4-trimethyl-1, 2-dihydroquinoline, C-27991, SR-01000854319, J-010251, SR-01000854319-2, BRD-K56792340-001-05-8, 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline, 9CI, 8CI, A10AE280-05F4-4846-ACAE-D565B0D263A2, Ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolinyl ether #, 124448-33-5, 8047-04-9, 8047-14-1

ID: 435

InChIKey: DEGAKNSWVGKMLS-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)CN(CC(=O)O)CC(=O)O)O)O)CN(CC(=O)O)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 65079
synonyms found at PubChem are:
calcein, 1461-15-0, Fluorexon, Oftasceine, Oftasceinum, Oftasceina, Fluorescein complexon, 2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid, UNII-V0YM2B16TS, V0YM2B16TS, CHEBI:51903, 2',7'-Bis((bis(carboxymethyl)amino)methyl)fluorescein, 2,7-Bis(N,N-bis(carboxymethyl)aminomethylene)fluorescein, N,N'-(3',6'-Dihydroxyspiro(phthalid-3,9'-xanthen)-2',7'-diyldimethyl)bis(iminodiessigsaeure), Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-, Oftasccine, 154071-48-4, Glycine, N,N'-((3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-2',7'-diyl)bis(methylene))bis(N-(carboxymethyl)-, Oftasceine [INN], Oftasceinum [INN-Latin], Oftasceina [INN-Spanish], Fluorexone, 2-{[(16-{[bis(carboxymethyl)amino]methyl}-12,15-dihydroxy-1-oxospiro[3-hydrois obenzofuran-3,9'-xanthene]-11-yl)methyl](carboxymethyl)amino}acetic acid, C30H26N2O13, EINECS 215-957-1, NSC 298193, AC1Q1HJI, AC1L22JM, SCHEMBL23435, CHEMBL1973733, DEGAKNSWVGKMLS-UHFFFAOYSA-N, MolPort-003-926-527, HY-D0040, KS-00000J6Y, ZINC4217203, MFCD00005049, NSC298193, SBB008848, AKOS015903938, CCG-214792, CS-7704, DB11184, MCULE-9834081696, NSC-298193, VZ32269, Fluorescein-bis(methyliminodiacetic acid), AK-72936, AN-22342, AS-35263, BR-72936, NCI60_002494, KB-224757, ST2408956, FT-0623371, ST50307393, W3190, M-7562, 2,N-bis(carboxymethyl)aminomethylene]fluorescein, Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein, SR-01000945252, SR-01000945252-1, Fluorescein,7'-bis[[bis(carboxymethyl)amino]methyl]-, I14-18258, Fluorescein, 2',7'-bis((bis(carboxymethyl)amino)methyl)- (8CI), Acetic acid,6'-dihydroxy-2',7'-fluorandiyl)bis(methylenenitrilo)]tetra-, 2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzo[b]furan-1,9'-xanthene]-2',7'-diyl)bis(methylene))bis(azanetriyl))tetraacetic acid, 2,2',2'',2'''-[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylenenitrilo)]tetraacetic acid, 2,2',2'',2'''-[(3',6'-dihydroxy-3-oxo-3h-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylenenitrilo)]tetraaceticacid, 2-[[7'-[[bis(carboxymethyl)amino]methyl]-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-2'-yl]methyl-(carboxymethyl)amino]acetic acid, 4370-08-5, Glycine,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-

ID: 436

InChIKey: DEMNUISBUXJRNU-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=O)C=C(O2)C3=CC(=CC=C3)F

biological descriptors:

CFTR relevance: inactive

Category:
Influence on CFTR function none
Order of interaction unknown
subcellular compartment unknown

reference list:

"MJ Kurth" "AS Verkman" "MF Springsteel" "M Eda" "EJ Niedzinski" "MH Nantz" "LJ Galietta" "K By" "MJ Haddadin"

CID is 261397
synonyms found at PubChem are:
2-(3-fluorophenyl)-4h-chromen-4-one, MLS002695201, 1744-33-8, 2-(3-fluorophenyl)chromen-4-one, 2-(3-Fluoro-phenyl)-chromen-4-one, NSC-93396, BAS 01121759, NSC93396, AC1Q4OK6, SCHEMBL8532, NCIOpen2_005865, Oprea1_329005, Oprea1_837330, CHEMBL54340, AC1L657Y, CTK0I0427, DTXSID40294002, HMS3087K23, ZINC266028, AKOS000603363, MB02193, SMR000117224, 2-(3-Fluorophenyl)-4H-1-benzopyran-4-one

ID: 437

InChIKey: DERJYEZSLHIUKF-UHFFFAOYSA-N
SMILES: CC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 9703
synonyms found at PubChem are:
Procarbazine hydrochloride, 366-70-1, PROCARBAZINE HCl, Matulane, Nathulane, Natunalar, MIH hydrochloride, PCB hydrochloride, Procarbazine.HCl, Ibenzmethyzine hydrochloride, Natulan hydrochloride, Procarbazine chloridrate, UNII-XH0NPH5ZX8, Ibenzmethyzin hydrochloride, NCI-C01810, Procarbazine (Hydrochloride), CCRIS 531, NSC-77213, EINECS 206-678-6, NSC 77213, XH0NPH5ZX8, p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide hydrochloride, AI3-50844, 1-(p-Isopropylcarbamoylbenzyl)-2-methylhydrazine hydrochloride, 1-Methyl-2-(p-isopropylcarbamoylbenzyl)hydrazine hydrochloride, 1-Methyl-2-p-(isopropylcarbamoyl)benzohydrazine hydrochloride, CHEBI:71428, N-Isopropyl-p-(2-methylhydrazinomethyl)benzamide hydrochloride, 2-(p-(Isopropylcarbamoyl)benzyl)-1-methylhydrazine hydrochloride, N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochloride, NSC77213, Procarbazine hydrochloride (Matulane), N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide hydrochloride, Matulane (TN), N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide monohydrochloride, p-Toluamide, N-isopropyl-alpha-(2-methylhydrazino)-, hydrochloride, DSSTox_CID_1190, N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide hydrochloride, 4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide hydrochloride, Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)-, monohydrochloride, Chlorhydrate de 1-methyl 2 p (isopropylcarbamoyl)benzyl-hydrazine [French], MBH, DSSTox_RID_76000, DSSTox_GSID_21190, N-isopropyl-4-((2-methylhydrazinyl)methyl)benzamide hydrochloride, p-Toluamide, N-isopropyl-alpha-(2-methylhydrazino)-, monohydrochloride, Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride, NCGC00016438-01, Ro-4646711, CAS-366-70-1, 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride, SR-01000763375, N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride, Procarbazine hydrochloride [USAN:JAN], Procarbazine hydrochloride [USAN:USP:JAN], AC1L1TMP, IBZ, SCHEMBL4012, C12H20ClN3O, C12H19N3O.HCl, methyl)benzamide hydrochloride, KSC962K8H, MLS001401414, p-Toluamide, monohydrochloride, 671-16-9 (Parent), CHEMBL1200410, DTXSID3021190, CTK8G2583, KS-00000XHF, DERJYEZSLHIUKF-UHFFFAOYSA-N, MolPort-003-849-975, HMS1571O06, LS-96, BCP02880, Chlorhydrate de 1-methyl 2 p (isopropylcarbamoyl)benzyl-hydrazine, Procarbazine hydrochloride (Natulan), Tox21_110439, Tox21_302318, MFCD00072082, s1995, WLN: 1Y1&MVR D1MM1 &GH, N-isopropyl-4-((2-methylhydrazinyl), AKOS015895395, Tox21_110439_1, CCG-100985, CS-2392, MCULE-2203793025, NC00235, Procarbazine hydrochloride (JP17/USP), 366-70-1 (HCl), NCGC00016438-04, NCGC00255389-01, Ro-46467/1, AC-12163, AN-44552, AS-13285, BC204134, CPD000469151, H809, HY-13733, Ro 4 6467/1, SAM001246564, SMR000469151, BCP0726000264, AB0013275, AB2000412, Procarbazine hydrochloride, >=98% (HPLC), FT-0083574, FT-0603386, P2550, C07376, D00478, K-8168, 366P701, A823326, I06-0654, SR-01000763375-4, Z1550675463, 1-methyl-2-p-(isopropylcarbamoyl)benzohydrazide hydrochloride, 4-[(methylhydrazo)methyl]-N-propan-2-ylbenzamide hydrochloride, 2-(p-(iso propylcarbamoyl)benzyl)-1-methylhydrazine hydrochloride, 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide hydrochloride, N-isopropyl-alp ha-(2-methylhydrazino)-p-toluamide hydrochloride, 4-[(2-methyl-hydrazino)-methyl]-benzoic acid isopropylamide hydrochloride, 4-[(2-methylhydrazinyl)methyl]-N-propan-2-yl-benzamide hydrochloride, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide monohydrochloride, N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride, Procarbazine hydrochloride, United States Pharmacopeia (USP) Reference Standard, Procarbazine Hydrochloride|||Natulan|||4-[(2-Methylhydrazinyl)methyl]-N-propan-2-ylbenzamide hydrochloride, AC1L9AV6, Methyl-[[4-(propan-2-ylcarbamoyl)phenyl]methylamino]azanium Chloride, SCHEMBL14973557, AKOS026750120

ID: 438

InChIKey: DERZBLKQOCDDDZ-JLHYYAGUSA-N
SMILES: C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1547484
synonyms found at PubChem are:
cinnarizine, Stugeron, 298-57-7, Dimitronal, Stutgin, Dimitron, Folcodal, Midronal, Mitronal, Stutgeron, Glanil, Labyrin, Lazeta, Marisan, Toliman, Sepan, Cinarizine, Cinnarizinum, Aplactan, Cinarizina, Cinnageron, Cinazyn, Cinaperazine, Libotasin, Senoger, Votegol, Zepamol, 1-Cinnamyl-4-(diphenylmethyl)piperazine, Cero-Aterin, R 516, 1-Benzhydryl-4-cinnamylpiperazin, Cinarizina [INN-Spanish], Cinnarizinum [INN-Latin], 516 MD, Processine, Sedatromin, Spaderizine, Aplexal, Apotomin, Carecin, Cerebolan, Cinnacet, Corathiem, Denapol, Giganten, Hilactan, Ixertol, Katoseran, Siptazin, Artate, Olamin, 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine, Eglen, R 1575, Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-, Cinnarizine [USAN:INN:BAN:JAN], UNII-3DI2E1X18L, Cerepar, (E)-1-Benzhydryl-4-cinnamylpiperazine, 16699-20-0, 1-trans-Cinnamyl-4-diphenylmethylpiperazine, R-516, C26H28N2, EINECS 206-064-8, MD 516, 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine, BRN 0626121, CHEMBL43064, Cinnarizine (JAN/USAN/INN), MLS000028498, 3DI2E1X18L, Piperazine, 1-cinnamyl-4-(diphenylmethyl)-, CHEBI:31403, 1-Benzhydryl-4-cinnamylpiperazine, DERZBLKQOCDDDZ-JLHYYAGUSA-N, N-Benzhydryl-N'-cinnamylpiperazine, 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine, Cinnipirine, 1-benzhydryl-4-[(E)-cinnamyl]piperazine, SMR000058307, DSSTox_CID_2821, C 5270, R-1575, DSSTox_RID_76744, DSSTox_GSID_22821, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine, 4-((2E)-3-phenylprop-2-enyl)-1-(diphenylmethyl)piperazine, Stonoron, Cinnarizine Stugeron, SR-01000003093, 1-(Diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)piperazine, Stunarone, 1-Cinnamyl-4-diphenylmethylpiperazine, Stunarone (TN), NCGC00015246-02, Stugeron (TN), CAS-298-57-7, Cinnarizine, powder, Prestwick_115, Piperazine, (E)-, AC1LU5GC, Opera_ID_1776, Prestwick2_000278, Prestwick3_000278, D0Q3YO, Lopac0_000314, SCHEMBL44957, SCHEMBL44958, BSPBio_000156, MLS001148649, MLS002207295, MLS002222167, ARONIS27007, BPBio1_000172, GTPL9072, DTXSID3022821, cid_1547484, AOB5321, CHEBI:131176, MolPort-002-056-760, HMS1568H18, HMS2095H18, HMS2234B20, HMS3260P10, HMS3712H18, component of Emesazine (Salt/Mix), 7002-58-6 (di-hydrochloride), EBD32904, HY-B1090, Tox21_110109, Tox21_500314, BDBM50017657, MFCD00056037, NSC290687, SBB057016, STK216257, ZINC19632891, AKOS002134299, Stugeron|Dimitronal|Stutgin|Cinarizine, Tox21_110109_1, CCG-204409, CS-4656, KS-5155, LP00314, NSC-290687, QTL1_000023, NCGC00018187-03, NCGC00018187-04, NCGC00018187-05, NCGC00018187-06, NCGC00018187-07, NCGC00018187-09, NCGC00021488-03, NCGC00021488-04, NCGC00021488-05, NCGC00260999-01, AN-25314, SC-14096, ST069378, LS-111394, EU-0100314, S4727, 1412-EP2275420A1, 1412-EP2280008A2, 1412-EP2298764A1, 1412-EP2298765A1, 1412-EP2305219A1, D01295, J10228, 298C577, A820077, L001227, 1-Benzhydryl-4-[3-phenyl-2-propenyl]piperazine #, I01-3582, SR-01000003093-2, SR-01000003093-6, W-106970, W-110442, 1-benzhydryl-4-[(2E)-3-phenylprop-2-enyl]piperazine, BRD-K07220430-001-03-6, BRD-K74927006-001-01-2, 1-[di(phenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine, 1-(diphenylmethyl)-4-(3-phenylprop-2-en-1-yl)piperazine, 1-(diphenylmethyl)-4-[(E)-3-phenylprop-2-enyl]piperazine, Cinnarizine, European Pharmacopoeia (EP) Reference Standard, Cinnarizine; 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine

ID: 439

InChIKey: DEUFHKWBUJBCRS-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(C(=C1O)C(=O)CC(C)C)OC3=C2C(=C(C(=C3C(=O)CC(C)C)O)C)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4445621
synonyms found at PubChem are:
RHODOMYRTOXIN, KBio2_001947, AC1NBMKV, Spectrum_001467, SpecPlus_000525, Spectrum2_001629, Spectrum3_001613, Spectrum4_001884, Spectrum5_000508, BSPBio_003245, KBioGR_002412, KBioSS_001947, DivK1c_006621, SPBio_001697, CHEMBL3039219, SCHEMBL12210330, CHEBI:92239, KBio1_001565, KBio2_004515, KBio2_007083, KBio3_002465, CCG-38749, ZINC03978776, NCGC00178189-01, BRD-K13725475-001-01-6, 3-methyl-1-[1,3,7,9-tetrahydroxy-2,8-dimethyl-6-(3-methylbutanoyl)dibenzofuran-4-yl]butan-1-one

ID: 440

InChIKey: DEYLVDCFTICBTB-WCBMZHEXSA-N
SMILES: CN1[C@@H]([C@H](CC1=O)C(=O)O)C2=CN=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 671220
synonyms found at PubChem are:
33224-01-0, trans-4-Cotininecarboxylic acid, trans-4'-Carboxycotinine, (2S,3S)-1-methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid, 3-Pyrrolidinecarboxylic acid, 1-methyl-5-oxo-2-(3-pyridinyl)-, (2S,3S)-, trans-1-Methyl-4-carboxy-5-(3-pyridyl)-2-pyrrolidinone, TimTec1_003237, (2S,3S)-1-methyl-5-oxo-2-(3-pyridyl)pyrrolidine-3-carboxylic acid, AC1LDOOP, AC1Q3XKX, SCHEMBL2637052, CHEMBL2165407, CTK1C0888, ZINC32345, DEYLVDCFTICBTB-WCBMZHEXSA-N, MolPort-001-790-918, HMS1543D03, BB_NC-01522, SBB003355, AKOS015955815, trans-4-Cotininecarboxylic acid, 97%, MCULE-3895723368, ST044506, M1053, KS-00001479, J-019095, I14-94540, (2S,3S)-1-methyl-5-oxo-2-pyridin-3-ylpyrrolidine-3-carboxylic acid, 3-Pyrrolidinecarboxylicacid, 1-methyl-5-oxo-2-(3-pyridinyl)-, (2S,3S)-

ID: 441

InChIKey: DEZFNHCVIZBHBI-ZHACJKMWSA-N
SMILES: CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)/C=C/C4=CC=CC=C4)OC(C=C3)(C)C)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281847
synonyms found at PubChem are:
rottlerin, Mallotoxin, 82-08-6, Kamalin, UNII-E29LP3ZMUH, EINECS 201-395-4, NSC 56346, NSC 94525, E29LP3ZMUH, BRN 0070757, CHEMBL34241, BMK1-F10, CHEBI:8899, NSC56346, NSC94525, R 5648, (E)-1-(6-((3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl)-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-phenyl-2-propen-1-one, 1-[6-(3-Acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenyl-propenone, 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one, 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl]-3-phenylprop-2-en-1-one, (2E)-1-[6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenylprop-2-en-1-one, (E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one, (E)-1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl]-3-phenylprop-2-en-1-one, Acetophenone, 3'-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl)-2',4',6'-trihydroxy-5'-methyl-, SR-01000076106, 1-{6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl}-3-phenylprop-2-en-1-one, R5648 (Rottlerin), AC1NQZ6C, BiomolKI_000058, BiomolKI2_000064, D0R1JI, Lopac0_001052, BSPBio_001080, 5-18-05-00695 (Beilstein Handbook Reference), MLS003370622, SCHEMBL148175, GTPL2611, SCHEMBL1537089, BCBcMAP01_000019, CHEBI:92065, DTXSID30231502, MolPort-003-959-457, HMS1362F21, HMS1792F21, HMS1990F21, HMS3263C06, HMS3403F21, 1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one, ZINC3874886, Tox21_501052, BDBM50126829, BS0167, CCG-36482, LMPK12120428, MFCD00017361, NSC-56346, NSC-94525, AKOS024282482, LP01052, IDI1_002135, NCGC00025228-02, NCGC00025228-03, NCGC00025228-04, NCGC00025228-05, NCGC00025228-06, NCGC00025228-07, NCGC00025228-08, NCGC00025228-09, NCGC00025228-10, NCGC00025228-11, NCGC00261737-01, 2-Propen-1-one, 1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-, (2E)-, HY-18980, LS-13446, SMR000058242, ST056358, CS-0014823, EU-0101052, C10721, SR-01000076106-2, SR-01000076106-3, SR-01000076106-6, BRD-K03816923-001-03-9, BRD-K39256324-001-01-5, I14-101598, (E)-1-[6-(3-Acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenyl-propenone, (E)-1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-chromen-8-yl]-3-phenyl-prop-2-en-1-one, (E)-1-[6-[(3-Acetyl-2,4,6-trihydroxy-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one, 3'-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl)-2',4',6'-trihydroxy-5'-methyl-acetophenone, 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone, 3-{[8-((2E)-3-phenylprop-2-enoyl)-5,7-dihydroxy-2,2-dimethyl(2H-chromen-6-yl)] methyl}-1-acetyl-2,4,6-trihydroxy-5-methylbenzene, 6-(3-Acetyl-2,4,6-trihydroxy-5-methylbenzyl)-2,2-dimethyl-8-(3-phenylpropenoyl)-2H-1-benzopyran-5,7-diol

ID: 442

InChIKey: DFAXGZYTCIFHEW-PUJYRUHLSA-N
SMILES: CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=CC(=C(C=C5CCN4)O)OC)OC)OC.O.O.O.O.O.O.O.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6420016
synonyms found at PubChem are:
Cephaeline dihydrochloride heptahydrate, UNII-H5P411P33C, H5P411P33C, 6487-30-5, Prestwick_784, AC1O4WHY, DTXSID20215159, HMS1569E18, (1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol heptahydrate dihydrochloride

ID: 443

InChIKey: DFHAXXVZCFXGOQ-UHFFFAOYSA-K
SMILES: C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 44561
synonyms found at PubChem are:
FOSCARNET SODIUM, 63585-09-1, Foscavir, Triapten, Trisodium phosphonoformate, Trisodium carboxyphosphate, Foscarnet sodique, Foscarneto sodico, Foscarnetum natricum, Foscarnet sodico, Foscarnet sodico [Spanish], Foscarnet sodique [French], Foscarnetum natricum [Latin], Virudin, Foscarnet sodique [INN-French], Foscarneto sodico [INN-Spanish], EHB 776, Foscarnetum natricum [INN-Latin], trisodium phosphonatoformate, UNII-8C5OQ81LWT, DRG-0017, Phosphonoformic acid, trisodium salt, Foscarnet trisodium, Foscavir (TN), EHB-776, CNa3O5P, Foscarnet sodium [USAN:INN:BAN], A 29622, 8C5OQ81LWT, Dihydroxyphosphinecarboxylic acid oxide trisodium salt, Foscarnet sodium (USAN/INN), CHEBI:141644, foscarnet sodium hexahydrate, trisodium carboxyphosphate (anhydrous), trisodium phosphonoformate (anhydrous), Forscarnet sodium, NCGC00094941-01, Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt, trisodium dioxidophosphanecarboxylate oxide, trisodium dioxidophosphinecarboxylate oxide, DSSTox_CID_3078, Trisodium phosphonoformate hexahydrate, DSSTox_RID_76865, A-29622, DSSTox_GSID_23078, Foscarnet sodium hydrate, PFA & rIFN.alpha.A, CHEMBL754, MSL & PFA, Gefin, Foscarnet sodium hydrate (JAN), CAS-63585-09-1, dihydroxyphosphanecarboxylic acid oxide, HS-0008, trisodium phosphonatoformate hexahydrate, Gefin Hydrate, Foscavir Hydrate, PFA Hydrate, sodium dioxidophosphanecarboxylate oxide hydrate(3:1:6), Triapten Hexahydrate, Phosphonoformate(trisodium) & Recombinant Alpha-A Interferon, EHB 776 Hydrate, Foscarnet sodium [USAN:USP:INN:BAN], Dihydroxyphosphinecarboxylic acid oxide and MSL, neutralizing monoclonal antibody, A 29622 Hydrate, Foscarnet & IFN-ALPHA, D0OT0O, AC1NB82R, ARONIS24504, SPECTRUM1502019, AC1L2C37, DTXSID6023078, CTK8F9927, HMS502N17, KS-00002WVP, 4428-95-9 (Parent), HMS1921D18, HMS2092N15, HMS3651J20, phosphonoformic acid trisodium salt, Phosphonoformic acid & IFN-ALPHA, BCP14044, Tox21_111364, CCG-40026, s3076, AKOS003599741, AKOS015951387, Tox21_111364_1, AC-2085, KS-1418, NCGC00094941-02, NCGC00178317-03, AC-19808, AN-14335, BC209202, H529, AB1009540, LS-105952, Phosphonoformic Acid Trisodium Salt Hydrate, FT-0626544, D00579, J10328, Phosphono-formic Acid Trisodium Salt Hexahydrate, 1,1-Dihydroxy-phosphinecarboxylic Acid 1-Oxide Sodium Salt Hydrate, 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt Hydrate, NCGC00168467-01

ID: 444

InChIKey: DFMAXQKDIGCMTL-UHFFFAOYSA-N
SMILES: COC1=C2C=COC2=C(C3=C1C=CC(=O)O3)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 68079
synonyms found at PubChem are:
Isopimpinellin, 482-27-9, 5,8-Dimethoxypsoralen, 5,8-Dimethoxypsoralene, 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one, 4,9-Dimethoxy-furo[3,2-g]chromen-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dimethoxy-, UNII-20GCF755G6, CCRIS 4347, 5,8-Dimethoxy-6,7-furanocoumarin, NSC401288, NSC 217988, NSC 401288, 4,9-dimethoxyfuro[3,2-g]chromen-7-one, 4,9-Dimethoxy-7H-furo(3,2-G) (1)benzopyran-7-one, CHEBI:28853, 20GCF755G6, 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one, Q-100529, 7H-Furo[3,2-g][1]benzopyran-7-one,4,9-dimethoxy-, 7H-Furo[3, 4,9-dimethoxy-, 7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dimethoxy- (8CI), Dimethylpsoralen, 5,9-Dimethoxypsoralen, Spectrum_000624, SpecPlus_000154, 5, 8-Dimethoxypsoralene, Spectrum2_000308, Spectrum3_001232, Spectrum4_001442, Spectrum5_000023, AC1L28ZK, AC1Q6AY5, Oprea1_132007, Oprea1_593894, BSPBio_002704, KBioGR_001923, KBioSS_001104, SPECTRUM300012, MLS000876836, DivK1c_006250, SCHEMBL498907, SPBio_000276, CHEMBL140796, MEGxp0_000706, ACon1_002361, CTK4J0725, DFMAXQKDIGCMTL-UHFFFAOYSA-, KBio1_001194, KBio2_001104, KBio2_003672, KBio2_006240, KBio3_002204, DTXSID30197457, DFMAXQKDIGCMTL-UHFFFAOYSA-N, MolPort-000-882-064, HMS2270M12, Isopimpinellin, analytical standard, ZINC314951, BDBM50361386, CCG-38585, NSC217988, STK368476, AKOS000278000, Isopimpinellin (4,9-Dimethoxypsoralen), MCULE-5163280216, NSC-217988, NSC-401288, SDCCGMLS-0066520.P001, NCGC00095569-01, NCGC00095569-02, NCGC00095569-03, 4CN-1065, AN-45204, BAS 00704724, CC-29668, LS-70709, NCI60_003765, SC-97796, SMR000440593, ZB010380, 4,9-Dimethoxy-7-oxofuro[3,2-g]chromene, 5,9-dimethoxyfurano[3,2-g]chromen-2-one, 4,9-Dimethoxyfuro[3,2-g]benzopyran-7-one, TR-031106, FT-0603412, I0861, ST50308983, W1277, 5,9-dimethoxy-2H-furo[3,2-g]chromen-2-one, C02162, 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one #, C-14994, SR-01000778471, SR-01000778471-2, BRD-K72253829-001-02-8, BRD-K72253829-001-03-6, BRD-K72253829-001-07-7, I14-13386, 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one, 9CI, 7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dimethoxy- (8CI)(9CI), InChI=1/C13H10O5/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11/h3-6H,1-2H3

ID: 445

InChIKey: DFURNQJNFBMYHM-UHFFFAOYSA-N
SMILES: C1=C(C=C(C(=C1O)O)O)C2=COC3=CC(=C(C(=C3C2=O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5781144
synonyms found at PubChem are:
IRIGENOL, KBio2_003741, AC1NXHQM, Spectrum_000693, Spectrum2_000801, Spectrum3_000207, Spectrum4_001603, Spectrum5_000325, BSPBio_001793, KBioGR_001945, KBioSS_001173, SPECTRUM201182, SPBio_000661, SCHEMBL2465996, CHEMBL1438439, KBio2_001173, KBio2_006309, KBio3_001293, CCG-39251, SDCCGMLS-0066397.P001, NCGC00095500-01, NCGC00095500-02, NCGC00179002-01, 3',4',5,5',6,7-Hexahydroxyisoflavone, BRD-K57398215-001-02-2, BRD-K57398215-001-03-0, 5,6,7-trihydroxy-3-(3,4,5-trihydroxyphenyl)chromen-4-one, 4935-93-7

ID: 446

InChIKey: DFWCPLGXFMSUCW-UHFFFAOYSA-N
SMILES: CN(C)CCCSC(=N)N.Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 90045
synonyms found at PubChem are:
Dimaprit Dihydrochloride, 23256-33-9, Dimaprit hydrochloride, Diamaprit-2HCl, Dimaprit-2HCl, USAF PD-40, 2-(3'-Dimethylaminopropylthio)pseudourea dihydrochloride, 2-(3-Dimethylaminopropyl)-2-thiopseudourea dihydrochloride, 3-(dimethylamino)propyl carbamimidothioate dihydrochloride, [3-(carbamimidoylsulfanyl)propyl]dimethylamine dihydrochloride, Pseudourea, 2-(3-(dimethylamino)propyl)-2-thio-, dihydrochloride, Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), SR-01000597945, S-(3-Dimethylaminopropyl)-isothiourea dihydrochloride, S-[3-dimethylaminopropyl]-isothiourea dihydrochloride, C6H15N3S.2ClH, AE-641/25069014, Dimaprit.2HCl, Dimaprit 2HCl, AC1L3J5I, AC1Q3A06, SCHEMBL7174665, CTK8F9221, DTXSID90177831, DFWCPLGXFMSUCW-UHFFFAOYSA-N, MolPort-003-983-556, HMS1571E07, 65119-89-3 (Parent), BCP27612, 2377AH, BN0189, MFCD00069260, AKOS015951329, Carbamimidothioic acid, 3-(dimethylamino)propyl ester, dihydrocloride (9CI), BCP9000610, CCG-220983, MCULE-2433505845, NE11168, Dimaprit dihydrochloride, >=98% (NMR), AB1009194, LS-126101, B6328, FT-0765520, EN300-133335, C-54147, J-015056, S-(3-Dimethylaminopropyl)isothiourea dihydrochloride, SR-01000597945-1, SR-01000597945-2, S-(3-Dimethylaminopropyl)- isothiourea dihydrochloride, S-[3-(Dimethylamino)propyl]isothiourea dihydrochloride, Z1649893059, Carbamimidothioic acid, 3-(dimethylamino)propyl ester, dihydrocloride

ID: 447

InChIKey: DGABKXLVXPYZII-SIBKNCMHSA-N
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5283820
synonyms found at PubChem are:
HYODEOXYCHOLIC ACID, 83-49-8, Iodeoxycholic acid, HDCA, 7-Deoxyhyocholic acid, Hyodesoxycholic acid, UNII-7A33Y6EHYK, Hyodeoxycholic acid (HDCA), alpha-Hyodeoxycholic acid, 6alpha-Hydroxylithocholate, NSC 60672, 7A33Y6EHYK, 3alpha,6alpha-Dihydroxy-5beta-cholanoic acid, CHEBI:52023, Hyodesoxycholsaeure, DGABKXLVXPYZII-SIBKNCMHSA-N, Hyodeoxycholate, 3alpha,6alpha-Dihydroxy-5beta-cholan-24-oic acid, 6|A-Dihydroxy-5|A-cholan-24-oic acid, 3alpha,6alpha-Dihydroxy-5beta-cholanic acid, Cholan-24-oic acid, 3,6-dihydroxy-, (3a,5b,6a)-, 6-alpha-Hydroxylithocholic acid, EINECS 201-483-2, 3alpha,6alpha-Dihydroxycholanic acid, BRN 3218394, 3|A, 5-beta-Cholanic acid-3-alpha,6-alpha-diol, .alpha.-Hyodeoxycholic acid, 3alpha,6alpha-Dihydroxy-5beta-cholan-24-saeure, 3-alpha,6-alpha-Dihydroxy-5-beta-cholan-24-oic acid, Cholan-24-oic acid, 3,6-dihydroxy-, (3alpha,5beta,6alpha)-, Hyodesoxycholsaure, 3.alpha.,6.alpha.-Dihydroxycholanic acid, 3|A,6|A-Dihydroxy-5|A-cholan-24-oic acid, 3.alpha.,6.alpha.-Dihydroxy-5.beta.-cholanic acid, 3alpha,6alpha-Dihydroxy-5 beta-cholan-24-oic acid, HYODEOXYCHOLIC_ACID, 3.alpha.,6.alpha.-Dihydroxy-5.beta.-cholanoic acid, 5-beta-Cholan-24-oic acid, 3-alpha,6-alpha-dihydroxy-, AC1NR33U, 4-10-00-01600 (Beilstein Handbook Reference), Hyodeoxycholic acid, >=98%, SCHEMBL207643, 5 beta-Cholan-24-oic acid-3alpha,6alpha-diol, AHRO-001, CHEMBL272621, Cholan-24-oic acid, 3,6-dihydroxy-, (3.alpha.,5.beta.,6.alpha.)-, MolPort-016-633-329, 6-.alpha.-Hydroxylithocholic acid, (R)-4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid, ZINC3918159, BDBM50375596, LMST04010024, MFCD00003681, s2311, 10421-49-5 (hydrochloride salt), AKOS022168200, DB11789, SMP1_000164, NCGC00386169-01, AJ-47432, AK323621, AS-14254, K489, AB0014249, C15517, 003H681, 5-.beta.-Cholanic acid-3-.alpha.,6-.alpha.-diol, W-104141, BRD-K44009692-001-02-3, (3alpha,5beta,6alpha)-3,6-Dihydroxycholan-24-oic acid, 5beta-Cholan-24-oic acid, 3alpha,6alpha-dihydroxy- (8CI), 3-.alpha.,6-.alpha.-Dihydroxy-5-.beta.-cholan-24-oic acid, 5.beta.-Cholan-24-oic acid, 3.alpha.,6.alpha.-dihydroxy-, 3,6-Dihydroxy-5.beta.-cholan-24-oic acid, (3.alpha.,6.alpha.)-, (4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

ID: 448

InChIKey: DGAIEPBNLOQYER-UHFFFAOYSA-N
SMILES: CN(CC(CO)O)C(=O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)NC(=O)COC)I

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3736
synonyms found at PubChem are:
iopromide, 73334-07-3, Ultravist, Iopromidum, Ultravist 300, Ultravist 370, Iopromida, SHL 414C, Iopromidum [INN-Latin], Iopromida [INN-Spanish], ZK 35760, EINECS 277-385-9, BRN 7085608, CHEBI:63578, N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N-methylisophthalamide, n,n'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-n-methylisophthalamide, ZK-35760, DSSTox_CID_3163, DSSTox_RID_76898, DSSTox_GSID_23163, iopromid, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylisophthalamide, 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-((methoxyacetyl)amino)-N-methyl-, 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino)-N-methyl-2,4,6-triiodo-, 1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-3-N-methylbenzene-1,3-dicarboxamide, Ultravist 150, Ultravist 240, Ultravist (pharmacy bulk), Proscope, Ultrakon, Iopromide [USAN:INN:BAN], Iopromide [USAN:USP:INN:BAN], Ultravist (TN), NCGC00016923-01, Proscope (TN), CAS-73334-07-3, BAY86-4877, N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide, BAY 86-4877, AC1L1GLH, Prestwick0_000872, Prestwick1_000872, Prestwick2_000872, Prestwick3_000872, D07GNP, AC1Q4PC5, CHEMBL1725, Iopromide (JAN/USP/INN), SCHEMBL24546, BSPBio_000943, MLS002154045, Iopromide, analytical standard, SPBio_002864, BPBio1_001039, DTXSID0023163, SH-L-414C, C18H24I3N3O8, DGAIEPBNLOQYER-UHFFFAOYSA-N, MolPort-005-932-395, HMS1570P05, HMS2097P05, HMS2233O23, HMS3370M05, HMS3714P05, BCP08449, HY-B1362, Tox21_110684, Ultravist 300 In Plastic Container, AC-535, AKOS025402129, Tox21_110684_1, CCG-220872, DB09156, NCGC00179367-01, NCGC00179367-03, AN-15741, BC200690, CC-29577, I661, LS-29729, SMR001233368, AB00513942, CS-0013103, FT-0627283, D01893, 334I073, C-23779, SR-01000841262, SR-01000841262-2, Iopromide, European Pharmacopoeia (EP) Reference Standard, Iopromide, United States Pharmacopeia (USP) Reference Standard, Iopromide for system suitability 1, European Pharmacopoeia (EP) Reference Standard, Iopromide for system suitability 2, European Pharmacopoeia (EP) Reference Standard, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-N-methyl-5-{[(methyloxy)acetyl]amino}benzene-1,3-dicarboxamide, N-(2,3-dihydroxypropyl)-3-[(2,3-dihydroxypropyl)(methyl)carbamoyl]-5-[(1-hydroxy-2-methoxyethylidene)amino]-2,4,6-triiodobenzene-1-carboximidic acid, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N3-methyl-benzene-1,3-dicarboxamide

ID: 449

InChIKey: DGFYECXYGUIODH-UHFFFAOYSA-N
SMILES: C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71401
synonyms found at PubChem are:
guanfacine hydrochloride, GUANFACINE HCL, 29110-48-3, Tenex, Estulic, Intuniv, N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride, Guanfacine (hydrochloride), Guanfacin hydrochloride, 29520-14-7, BS 100-141, Connexyn, N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride, LON 798, UNII-PML56A160O, N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride, Tenex (TN), N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride, EINECS 249-443-3, Guanfacine hydrochloride [USAN:JAN], SPD 503, MLS000069745, PML56A160O, BS-100-141, N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride, SPD-503, N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide hydrochloride, Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride, Guanfacine hydrochloride (JAN/USP), n-carbamimidoyl-2-(2,6-dichlorphenyl)acetamidhydrochlorid, SMR000058453, G 1043, DSSTox_CID_25157, DSSTox_RID_80708, DSSTox_GSID_45157, N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide, [(2,6-Dichlorophenyl)acetyl]guanidine Hydrochloride, N-(aminoiminomethyl)-2,6-dichloro-benzeneacetamide hydrochloride, CAS-29520-14-7, SR-01000075893, NCGC00015469-05, Guanfacin, SPD503, Prestwick_740, Intuniv (TN), GuanfacineHydrochloride, Guarfacine Hydrochloride, Guanfacine hydrochloride [USAN:USP:JAN], Guanfascine Hydrochloride, C9H9Cl2N3O.HCl, Opera_ID_1928, D0WD8M, AC1L2G3E, C9H10Cl3N3O, SCHEMBL41681, MLS001077329, MLS002222252, AC1Q3P39, CHEBI:5559, CHEMBL1200494, DTXSID2045157, SCHEMBL15603414, CTK8C3871, CTK8G0106, MolPort-003-666-686, MolPort-019-997-499, HMS1569C19, Pharmakon1600-01505435, 29110-47-2 (Parent), BCP21710, KS-000017QB, Tox21_110159, Tox21_500519, ANW-70740, BG0397, MFCD00798230, NSC759121, s4693, AKOS015966858, AKOS030242245, Tox21_110159_1, API0006740, CCG-213439, CCG-220339, CS-1254, LP00519, NSC-759121, NCGC00015469-09, NCGC00093914-01, NCGC00093914-02, NCGC00180965-01, NCGC00261204-01, AS-12253, BC202678, HY-17416, LS-28474, Guanfacine hydrochloride, >=98% (HPLC), AB0011596, AX8239284, KB-258655, TC-159485, EU-0100519, FT-0630546, FT-0698181, G0414, D00606, W-5123, A826918, J-017395, S-877503, SR-01000075893-1, SR-01000075893-3, SR-01000075893-6, Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1), Guanfacine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard, N-[bis(azanyl)methylidene]-2-[2,6-bis(chloranyl)phenyl]ethanamide hydrochloride, AKOS026750369

ID: 450

InChIKey: DGGOLFCPSUVVHX-RTHJTPBESA-N
SMILES: C1[C@H](OC2=C(C1=O)C=CC(=C2O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C4=CC(=C(C=C4)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 101781
synonyms found at PubChem are:
Flavanomarein, 577-38-8, (S)-2-(3,4-Dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one, isookanine-7-glucoside, EINECS 209-411-1, Isookanin-7-glucoside, Isookanin-7-O-glucoside, AC1Q6NLS, AC1L2RJ5, BIDF1015, SCHEMBL2490125, CHEMBL1405715, ZX-AFC001535, ZINC13827634, CCG-208625, NCGC00163555-01, 3',4',7,8-Tetrahydroxyflavanone-7-O-glucoside, SR-05000002161, SR-05000002161-2, (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl beta-D-glucopyranoside, (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one, (S)-2-(3,4-Dihydroxy-phenyl)-8-hydroxy-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chroman-4-one, (S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)chroman-4-one, 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (2S)-

ID: 451

InChIKey: DGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 60699
synonyms found at PubChem are:
TOPOTECAN HYDROCHLORIDE, 119413-54-6, Topotecan Hcl, Hycamtin, Hycamptamine hydrochloride, Topotecan (Hydrochloride), Topotecan monohydrochloride, UNII-956S425ZCY, Topotecan hydrochloride [USAN], Nogitecan hydrochloride, DRG-0288, SK&F S-104864-A, NSC 609699, NSC-609699, NSC609699, 956S425ZCY, SKF 104864A, NCGC00095189-01, DSSTox_CID_25952, DSSTox_RID_81248, DSSTox_GSID_45952, (S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione monohydrochloride, Topotecan hydrochloride (USAN), CHEMBL1607, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-, SMR000466344, CAS-119413-54-6, SK&F-S-104864A, Evotropin, Topetecan, Potactasol (TN), (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride, (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Hydrochloride, (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride, AC1L1TQW, AC1Q3EIA, Topotecan HCl - Hycamtin, D0Z4XW, SCHEMBL7247, Hycamtin (TN) (GlaxoSmith), MLS000759456, MLS001401447, C23H23N3O5.HCl, SPECTRUM1505820, Nogitecan hydrochloride (JAN), DTXSID1045952, AOB6645, DGHHQBMTXTWTJV-BQAIUKQQSA-N, MolPort-003-666-754, HMS1922H22, Pharmakon1600-01505820, 10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride, BCP00930, KS-00000HA7, SKF-S 104864-A, Tox21_111478, BG0599, CCG-37460, CT0202, HY-13768A, NCGC00014925, NCI609699, NK-211, NSC759263, s1231, SK&F-S-104864-A, AKOS015900415, SK&F 104864-A, Tox21_111478_1, AC-1551, AN-7238, CS-1498, KS-1410, NC00177, NSC-759263, RL00754, NCGC00014925-06, NCGC00095189-02, NCGC00095189-03, AK-48920, BC203930, BR-48920, CPD000466344, SAM001246651, AB0012839, AX8001571, LS-172415, FT-0631095, D02168, S-5061, 413T546, C-22572, I14-051, E-89/001, 9-Dimethylaminomethyl-10-hydroxycamptothecin, HCl salt, (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0(2),(1)(1).0?,?.0(1)?,(2)?]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione hydrochloride, (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride, (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride, 1H-Pyrano[3',7]indolizino[1,2-b]quinoline- 3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-

ID: 452

InChIKey: DGMKFQYCZXERLX-UHFFFAOYSA-N
SMILES: CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)C1=CC=CC=C1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4922
synonyms found at PubChem are:
proglumide, 6620-60-6, 4-benzamido-5-(dipropylamino)-5-oxopentanoic acid, Binoside, Xylamide, dl-proglumide, Milid, Nulsa, Gastrotopic, Proglumidum, Midelid, Proglumida, Ulcutin, Milide, Xyde, Proglumidum [INN-Latin], Proglumida [INN-Spanish], Promide (parasympatholytic), CR 242, W-5219, Xylamide (gastroprotective agent), C18H26N2O4, (+-)-4-Benzamido-N,N-dipropylglutaramic acid, EINECS 229-567-4, 242 DL, W 5219, BRN 4151696, CHEMBL316561, CHEBI:32058, Glutaramic acid, 4-benzamido-N,N-dipropyl-, DL-, 4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoic acid, Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, DSSTox_CID_3516, Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-, (+-)-, DSSTox_RID_77060, DSSTox_GSID_23516, KXM, W-104770, 4-BENZOYLAMINO-5-DIPROPYLAMINO-5-OXOPENTANOIC ACID SODIUM SALT, 24485-90-3, SR-01000002970, Progumide, Xilamide, 4-(N,N-dipropylcarbamoyl)-4-(phenylcarbonylamino)butanoic acid, racemic proglumide, (RS)-proglumide, Proglumide,(S), Proglumide [USAN:BAN:INN:JAN], Proglumide [USAN:INN:BAN:JAN], NCGC00016676-01, (+-)-proglumide, Prestwick_602, CAS-6620-60-6, N-Benzoyl-N',N'-dipropyl-DL-isoglutamine Sodium-Potassium salt, Nulsa (TN), Spectrum_001332, AC1Q5KVC, Prestwick0_000240, Prestwick1_000240, Prestwick2_000240, Prestwick3_000240, Spectrum2_001406, Spectrum3_001444, Spectrum4_000425, Spectrum5_001591, D04HQT, AC1L1J8S, Lopac0_000832, SCHEMBL93339, BSPBio_000319, BSPBio_002907, GTPL893, KBioGR_000750, KBioSS_001812, MLS002154246, DivK1c_000684, SPECTRUM1501119, SPBio_001452, SPBio_002240, BPBio1_000351, DTXSID7023516, Proglumide (JP17/USAN/INN), SCHEMBL19994752, CHEBI:76266, CTK8B7675, HMS502C06, KBio1_000684, KBio2_001812, KBio2_004380, KBio2_006948, KBio3_002407, AOB5334, DGMKFQYCZXERLX-UHFFFAOYSA-N, MolPort-003-666-356, NINDS_000684, HMS1568P21, HMS1921F19, HMS2092D13, HMS2095P21, HMS2235B24, HMS3262H05, HMS3369D14, HMS3712P21, Pharmakon1600-01501119, HY-B1330, Tox21_110557, Tox21_500832, ANW-58129, BDBM50014888, CCG-39024, CR-242, NSC757841, SBB058173, AKOS015895810, Tox21_110557_1, AC-1274, API0007251, CS-8029, KS-1212, LP00832, MCULE-2438450007, NSC-757841, 4-Benzamido-N,N-dipropylglutaramic acid, IDI1_000684, N2-Benzoyl-N,N-dipropyl-alpha-glutamine, NCGC00015623-03, NCGC00015623-04, NCGC00015623-05, NCGC00015623-06, NCGC00015623-07, NCGC00015623-10, NCGC00094163-01, NCGC00094163-02, NCGC00094163-03, NCGC00094163-04, NCGC00261517-01, AK-87654, AN-15100, BC207728, H786, LS-71949, SC-18334, SMR001233513, SBI-0050809.P003, AX8149133, KB-240288, N(2)-benzoyl-N,N-dipropyl-alpha-glutamine, TC-146874, TL8004691, AB00052206, EU-0100832, FT-0654938, M-001, ST24043276, ST51015098, N2-(phenylcarbonyl)-N,N-dipropyl-a-glutamine, 4-Benzoylamino-4-dipropylcarbamoyl-butyric acid, D01818, rac-N(2)-benzoyl-N,N-dipropyl-alpha-glutamine, AB00052206_08, 4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid, 620P606, 4-benzamido-5-(dipropylamino)-5-oxo-pentanoic acid, I06-1540, N~2~-(phenylcarbonyl)-N,N-dipropyl-alpha-glutamine, SR-01000002970-2, SR-01000002970-4, SR-01000002970-7, 4-(Benzoylamino)-5-(dipropylamino)-5-oxovaleric acid, BRD-A44863528-001-05-8, BRD-A44863528-001-08-2, 25727-74-6

ID: 453

InChIKey: DGMPVYSXXIOGJY-UHFFFAOYSA-N
SMILES: CCCCC1=CN=C(C=C1)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3442
synonyms found at PubChem are:
fusaric acid, 5-Butylpicolinic acid, 536-69-6, 5-Butylpyridine-2-carboxylic acid, Fusarinic acid, 5-Butyl-2-pyridinecarboxylic acid, 2-Pyridinecarboxylic acid, 5-butyl-, Picolinic acid, 5-butyl-, 5-n-Butylpyridine-2-carboxylic acid, UNII-JWJ963070N, HSDB 3487, 5-Butylpyridine-3-carboxylic acid, 5-Butyl-pyridine-2-carboxylic acid, EINECS 208-643-0, NSC 19870, BRN 0125804, CHEMBL24510, CHEBI:5199, DGMPVYSXXIOGJY-UHFFFAOYSA-N, JWJ963070N, NSC19870, TNP00268, NCGC00015441-04, CAS-536-69-6, F-9000, Prestwick_233, 5-Butyl-2-pyridinedicarboxylic Acid, 5-n-butylpicolinic acid, AC1Q2VFD, AC1Q2VLS, Prestwick0_000442, Prestwick1_000442, Prestwick2_000442, Prestwick3_000442, 5-n-butyl picolinic acid, Lopac-F-6513, DSSTox_CID_3085, ACMC-209l9f, AC1L1FY2, DSSTox_RID_76868, DSSTox_GSID_23085, Lopac0_000526, Oprea1_115508, WLN: T6NJ BVQ E4, BSPBio_000484, 5-22-02-00384 (Beilstein Handbook Reference), MLS002153813, SCHEMBL178006, SPBio_002423, BPBio1_000534, DTXSID5023085, CTK1G9873, MolPort-001-787-743, HMS1569I06, HMS2096I06, HMS2230M05, HMS3261J13, HMS3369P03, Picolinic acid, 5-butyl- (8CI), 2-Pyridinecarboxylicacid, 5-butyl-, ZINC1531682, Tox21_110149, Tox21_500526, 7659AB, ANW-31825, BDBM50000439, BG0500, MFCD00006298, NSC-19870, AKOS015891748, CCG-204616, Fusaric acid, from Gibberella fujikuroi, LP00526, MCULE-2488661517, VP14790, NCGC00015441-01, NCGC00015441-02, NCGC00015441-03, NCGC00015441-05, NCGC00015441-06, NCGC00015441-07, NCGC00015441-08, NCGC00015441-10, NCGC00093919-01, NCGC00093919-02, NCGC00093919-03, NCGC00261211-01, AJ-26731, BBV-39686440, CC-21428, KB-52222, SC-93977, SMR001233184, ST057174, AX8000202, DB-052375, LS-130745, TC-120570, EU-0100526, F0227, FT-0626585, A-8604, A19903, C10146, F 6513, 5-Butyl-pyridine-2-carboxylic acid (fusaric acid), C-06556, SR-01000075634, I02-1634, SR-01000075634-1, BRD-K87049188-001-03-6, Fusaric acid, for HPLC derivatization, >=99.0% (HPLC), InChI=1/C10H13NO2/c1-2-3-4-8-5-6-9(10(12)13)11-7-8/h5-7H,2-4H2,1H3,(H,12,13

ID: 454

InChIKey: DGOWDUFJCINDGI-UHFFFAOYSA-N
SMILES: CCC(=O)N1CCN(CC1)C(=O)C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 4223812
synonyms found at PubChem are:
SUNIFIRAM, 314728-85-3, DM 235, 1-(4-benzoylpiperazin-1-yl)propan-1-one, DM-235, Piperazine, 1-benzoyl-4-(1-oxopropyl)-, 1-(4-benzoyl-1-piperazinyl)-1-Propanone, UNII-66924E735K, 66924E735K, Sunifiram/DM235, Sunifiram/DM-235, DM 235, solid, AC1N6ZNX, Lopac-D-5689, Lopac0_000340, MLS002153160, SCHEMBL195641, CHEMBL309176, ZINC8819, CTK8E7496, DTXSID10400996, MolPort-003-941-103, HMS2235F24, HMS3261C21, HMS3369F12, KS-00001D9G, ZX-AH001740, Tox21_500340, AKOS008915318, API0008584, CCG-204435, CS-2193, HS-0093, LP00340, MCULE-5011831910, ABA-9502018, NCGC00015350-01, NCGC00015350-02, NCGC00015350-03, NCGC00015350-04, NCGC00093779-01, NCGC00093779-02, NCGC00261025-01, AK163811, DA-17321, HY-17550, KB-89724, SMR001230654, AX8294923, LS-110345, RT-012387, EU-0100340, FT-0699900, ST24037308, Y1295, 1-Propanone, 1-(4-benzoyl-1-piperazinyl)-, VU0474076-1, D 5689, SR-01000075821, J-018438, SR-01000075821-1

ID: 455

InChIKey: DGXLEDCXMIJNPJ-UHFFFAOYSA-N
SMILES: CCCCCC(=O)CC1=CC(=CC(=C1C(=O)OC2=CC(=C(C(=C2)CC(=O)CCCCC)C(=O)O)OC)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6710684
synonyms found at PubChem are:
ARTHONIOIC ACID, Arthonia acid, KBio3_002037, Spectrum_001548, AC1O8JWL, Spectrum2_001724, Spectrum3_001029, Spectrum4_001161, BSPBio_002817, KBioGR_001761, KBioSS_002028, SPECTRUM240942, SPBio_001768, CHEMBL1332204, KBio2_002028, KBio2_004596, KBio2_007164, CCG-38794, SDCCGMLS-0066521.P001, NCGC00095554-01, NCGC00095554-02, SR-05000002738, SR-05000002738-1, 4-[2,4-dihydroxy-6-(2-oxoheptyl)benzoyl]oxy-2-methoxy-6-(2-oxoheptyl)benzoic acid, 25556-24-5

ID: 456

InChIKey: DHZBEENLJMYSHQ-XCVPVQRUSA-N
SMILES: C[C@@]12[C@H]3CC[C@@H]([C@@]1(C(=O)OC2=O)C)O3

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5944
synonyms found at PubChem are:
cantharidin, 56-25-7, CANTHARIDINE, Cantharone, Kantaridin, Kantharidin, Cantharides camphor, Kantharidin [German], Caswell No. 157, 1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride, UNII-IGL471WQ8P, NSC61805, CCRIS 635, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione, BRN 0085302, AI3-04021, HSDB 2181, (3ar,4s,7r,7as)-3a,7a-dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione, exo-1,2-cis-Dimethyl-3,6-epoxyhexahydrophthalic anhydride, EINECS 200-263-3, NSC 61805, EPA Pesticide Chemical Code 013101, IGL471WQ8P, CHEMBL48449, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-rel-, CHEBI:64213, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, DHZBEENLJMYSHQ-XCVPVQRUSA-N, CAN [Alkaloid], MFCD00134968, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-, 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 2,3-Dimethyl-7-oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, 2,3-dimethyl-, (1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride, Hexahydro-3aalpha,7aalpha-dimethyl-4beta,7beta-epoxyisobenzofuran-1,3-dione, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3a-alpha,4-beta,7-beta,7a-alpha), Cantharides, (3a?,4?,7?,7a?)-Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, Cantharidin17, CAS-56-25-7, NCGC00016247-01, PubChem6009, Prestwick3_000885, 2,3-dicarboxylic anhydride, NCIMech_000301, BSPBio_000670, 5-19-05-00051 (Beilstein Handbook Reference), SCHEMBL152262, AC1Q296O, BPBio1_000738, Cantharides camphor, Cantharone, cid_6708701, CTK8E0309, MolPort-003-983-935, HMS2097B12, 1,6-epoxyperhydrophthalic anhydride, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3a.alpha.,4.beta.,7.beta.,7a.alpha.)-, ACT03236, BCP09819, HY-N0209, BDBM50090505, CCG-35382, CCG-36082, NSC-61805, ZINC17611186, AKOS015895930, AC-7967, API0001832, CS-4979, DB12328, FCH3878399, RL04124, 4,3-dione, hexahydro-3a,7a-dimethyl-, exo-1,6-epoxyhexahydrophthalic anhydride, NCGC00025212-02, NCGC00025212-03, NCGC00025212-04, NCGC00025212-05, AS-18735, LS-98756, NCI60_005413, SC-05366, WLN: T C555 A AO DVOVTJ C1 G1, AB00513946, Hexahydro-3a,7-epoxyisobenzofuran-1,3-dione, X1105, C16778, 7-Oxabicyclo[2.2.1]heptane-2, 2,3-dimethyl-, 134C968, SR-01000597585, I06-1213, SR-01000597585-1, BRD-K80684056-001-01-0, (1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione, (1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione, (1S,2R,6S,7R)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione, (1S,3S,4R,7R)-2,6-dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione, 4,3-dione, hexahydro-3a,7a-dimethyl-, (3a.alpha.,4.beta.,7.beta.,7a.alpha.)-, 1351357-43-1

ID: 457

InChIKey: DIAOGWYBBJCPAD-UHFFFAOYSA-N
SMILES: CCC1=C(C2=CC3=C(C(=C2C=C1)O)C(=O)C4=C(C=CC(=C4C3=O)O)O)C(=O)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 120369
synonyms found at PubChem are:
Cyclacidin, pi-Pyrromycinone, Bisanhydropyrromycinone, Bisanhydrorutilantinone, eta-Pyrromycinone, BRN 2711377, 1-Naphthacenecarboxylic acid, 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-, methyl ester, methyl 2-ethyl-5,7,10-trihydroxy-6,11-dioxo-6,11-dihydrotetracene-1-carboxylate, Methyl 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-1-naphthacenecarboxylate, 749-18-8, ciclacidine, Spectrum_001672, AC1L3QNA, AC1Q5ZQG, Spectrum2_000653, Spectrum3_000226, Spectrum4_000944, Spectrum5_000355, BSPBio_001871, KBioGR_001528, KBioSS_002152, SPECTRUM201605, 4-10-00-04135 (Beilstein Handbook Reference), SPBio_000685, CHEMBL1436035, CTK8D8810, KBio2_002152, KBio2_004720, KBio2_007288, KBio3_001371, DIAOGWYBBJCPAD-UHFFFAOYSA-N, HMS1923A17, CCG-39654, NCGC00095224-01, NCGC00095224-02, NCGC00095224-03, LS-94508, SR-05000002636, SR-05000002636-1, methyl 2-ethyl-5,7,10-trihydroxy-6,11-dioxotetracene-1-carboxylate

ID: 458

InChIKey: DIGWWZCEDODOMZ-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(N1CC3=CC=C(C=C3)F)C=CC(=C2)OC)CC(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3448892
synonyms found at PubChem are:
1-(4-Fluorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, NCGC00015432-01, Lopac-F-2927, AC1MQB55, Lopac0_000505, SCHEMBL1320560, CHEMBL1257014, ZINC2507398, CCG-204596, NCGC00015432-02, NCGC00015432-03, NCGC00093904-01, NCGC00093904-02, EU-0100505, F 2927, SR-01000075875, SR-01000075875-1, 2-[1-[(4-fluorophenyl)methyl]-5-methoxy-2-methylindol-3-yl]acetic acid, 1-(4-Fluorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, >=98% (HPLC), solid

ID: 459

InChIKey: DIOIOSKKIYDRIQ-UHFFFAOYSA-N
SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 62999
synonyms found at PubChem are:
Ciprofloxacin hydrochloride, Ciprofloxacin HCl, 93107-08-5, 86483-48-9, 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride, UNII-0MP32MFP6C, Cipro, CHEBI:310388, 0MP32MFP6C, ciprofloxacin hydrochloride (anh.), Cetraxal, Ciloxan, Ciprofloxacin monohydrochloride, 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid HCl, BAY-o 9867, DSSTox_CID_27768, DSSTox_RID_82545, DSSTox_GSID_47788, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride, 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride, 1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride, Q-200860, Bay-o-9867 monohydrate, Prestwick_67, 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride, 4-(3-Carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinolin-7-yl)-piperazin-1-ium; chloride, NSC620634, NCGC00016959-01, CAS-93107-08-5, Ciprofloxacin Hydrochloride Anhydrous, 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride, ciprofloxacine hydrochloride, Epitope ID:174846, AC1L1Y6P, AC1Q3E6U, Cambridge id 5807784, CHEMBL1202, SCHEMBL42310, C17H18FN3O3.HCl, ARONIS24122, CIPROFLOXACIN HCL/LACTATE, DTXSID1047788, HY-B0356A, BBC/258, DIOIOSKKIYDRIQ-UHFFFAOYSA-N, MolPort-002-338-774, BAY-O-9867, HMS1568G08, BCP13634, BCP14336, KS-000046JK, ZX-AS004472, Tox21_110712, 9311AF, BG0142, GP9406, SBB080619, AKOS005111008, ciprofloxacin hydrochloride (anhydrous), Tox21_110712_1, API0002028, CS-8134, KS-5012, NSC-620634, NCGC00016959-06, 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, hydrochloride, AC-23972, AK126819, AK176012, AN-35553, SC-12658, BIM-0048462.P001, AX8035163, KB-218801, LS-141564, FT-0623850, FT-0623851, Z-0831, F0001-2378, 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carboxylic acid hydrochloride, 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrochloride, 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride, 1-cyclopropyl-6-fluoro-4-oxo-7-piperazinylhydroquinoline-3-carboxylic acid, ch loride, 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylicacidhydrochloride, AKOS015896243, A841682, I06-2118, 1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; hydron; chloride, 1-cyclopropyl-6-fluoranyl-4-oxidanylidene-7-piperazin-1-yl-quinoline-3-carboxylic acid; hydron; chloride

ID: 460

InChIKey: DJDFFEBSKJCGHC-UHFFFAOYSA-N
SMILES: C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11079
synonyms found at PubChem are:
NAPHAZOLINE HYDROCHLORIDE, 550-99-2, Albalon, NAPHAZOLINE HCL, Rhinantin, Rhinoperd, Stricylon, Naphcon, Niazol, Rinofug, Vasocon, Opcon, Albalon Liquifilm, Clera hydrochloride, Naphazoline chloride, Privine hydrochloride, Prizole hydrochloride, Vasoclear, Coldan, Naphcon forte, Comfort Eye Drops, Degest-2, Naphazoliniumchlorid, Sanorin, Naphazolini chloridum, 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride, Naphthasolium chloride, 2-(1-Naphthylmethyl)imidazoline hydrochloride, Clear Eyes, NAFAZAIR, Naphazoline (hydrochloride), UNII-MZ1131787D, HSDB 2174, Naphthylmethylimidazolinhydrochlorid, EINECS 208-989-2, NSC 35711, MLS000028434, CHEBI:7470, 2-IMIDAZOLINE HYDROCHLORIDE, Naphazoline hydrochloride (Naphcon), 2-(1-Naphthylmethyl)-2-imidazoline monohydrochloride, MZ1131787D, 2-Imidazoline, 2-(1-naphthylmethyl)-, monohydrochloride, SMR000058292, 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, monohydrochloride, 2-(1-Naphthylmethyl)-2-Imidazoline Hydro- Chloride, W-105587, AC1LCWB1, 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride, CHEMBL1706, MolPort-000-703-064, 2-(naphthylmethyl)-2-imidazoline, chloride, Albacon, Naphcon;Albalon, 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride, SR-01000000067, Naphazoline hydrochloride [JAN], Prestwick_507, Albalon (TN), Vasocon (TN), component of Nasocon, Naphazoline hydrochloride [USP:JAN], Opera_ID_230, AC1L1WKK, SureCN1649580, SCHEMBL24153, C14H14N2.HCl, MLS001148448, MLS002222217, Naphazoline Hydrochloride,(S), SPECTRUM1500424, 835-31-4 (Parent), 2-Imidazoline, monohydrochloride, CTK5J7411, AOB5340, DJDFFEBSKJCGHC-UHFFFAOYSA-N, MolPort-002-904-680, HMS1568I13, HMS1920P11, Pharmakon1600-01500424, HY-B0446, NSC35711, BG0263, CCG-40122, MFCD00012554, NSC-35711, NSC757110, s2519, SBB017549, AKOS015908797, Naphazoline hydrochloride (JP17/USP), Naphazoline hydrochloride BP98 USP24, CS-2555, NC00523, NSC-757110, NCGC00094732-01, NCGC00094732-02, NCGC00094732-03, NCGC00094732-04, AN-15699, AS-16861, CPD000058292, LS-79667, SAM002554916, SC-46390, 2-(naphthalen-1-ylmethyl)-4,5-dihydro-, AB2000621, LS-175633, TR-019439, WLN: L66J B1- BT5M CN BUTJ &GH, FT-0603466, LT00114215, LT00233108, N0542, ST50319852, C07898, D00743, C-15060, I14-3428, SR-01000000067-3, 2-(1-naphthylmethyl)-4,5-dihydro-1H-imidazole hydrochloride, 4,5-Dihydro-2-(1-naphthylmethyl)-1H-imidazole Hydrochloride, 1H-Imidazole,5-dihydro-2-(1-naphthalenylmethyl)-, monohydrochloride, Naphazoline hydrochloride, European Pharmacopoeia (EP) Reference Standard, Naphazoline hydrochloride, United States Pharmacopeia (USP) Reference Standard, 35412-62-5, AKOS026749898, hydron; 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole; chloride, MCULE-8346078401

ID: 461

InChIKey: DJGAAPFSPWAYTJ-UHFFFAOYSA-M
SMILES: CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)CS(=O)(=O)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6236
synonyms found at PubChem are:
dipyrone, Analgin, Metamizole sodium, Methampyrone, Novalgin, 68-89-3, Methylmelubrin, Neomelurbrin, Algocalmin, sulpyrine, Metamizole, Novalgetol, Optalgin, Pyralgin, Sulpyrin, Narone, Algopyrine, Farmolisina, Nevralgina, Novamidazophen, Novaminsulfone, Pharmalgine, Alginodia, Analgine, Bonpyrin, Dimethone, Diprofarn, Feverall, Fevonil, Gifaril, Keypyrone, Metapyrin, Metilon, Noveltex, Paralgin, Pyretin, Pyrojec, Barone, Conmel, Sulpin, Neo-melubrine, Di-podil, Aminopyrine sodium sulfonate, Metamizolum natricum, Novaminsulfon, Novaminsulfonum, Analginum, Metamizolum, Sulpyrinum, Metamizolnatrium, Novaminsulfonium, ARPF, Novaminophenazone, Metamizole sodique, Novaminsulfone sodium, Metamizolo, Noraminophenazone sodium mesylate, Novaldin, Meamizol sodico, Metamizolo [Italian], Novamidazophenum, Sodium novaminsulfonate, Noraminophenazone, Pyretin (pharmaceutical), Sodium noramidopyrine methanesulfonate, Dipyrone [BAN], Metamizolo sodico [DCIT], Metamizol sodico [Spanish], Metamizolum natricum [Latin], Noramidopyrine methanesulfonate sodium, Sodium methylaminoantipyrine methanesulfonate, Noraminophenazone methanesulfonate sodium salt, Vetalgin, Sodium (antipyrinylmethylamino)methanesulfonate, Natrium novaminsulfonicum, Mexican aspirin, Metamizole sodique [INN-French], Dipyrone monohydrate, Metamizolum natricum [INN-Latin], Noramidopyrine methanesulfonate sodium salt, Metamizol monohydrate, UNII-VSU62Z74ON, Methylaminoantipyrine sodium methanesulfonate, Metamizole sodique [French], Noraminopyrine methanesulfonate sodium, CCRIS 4443, Dipyrone [anhydrous], Meamizol sodico [INN-Spanish], CHEBI:59033, Analgin (sodium salt), Methylaminophenyldimethylpyrazolone methanesulfonate sodium, EINECS 200-694-7, 4-Sodium methanesulfonate methylamine-antipyrine, Noramidopyrinium-methanesulphate natrium, VSU62Z74ON, (Antipyrinylmethylamino)methanesulfonic acid sodium salt, Dipyrone [USAN:BAN], Antipyrine, 4-(methylamino)-, monomethosulfate, sodium salt, Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt, Sodium phenyldimethylpyrazolon-methylamino-methane sulfonate, Phenyl dimethyl pyrazolon methyl aminomethane sodium sulfonate, Noramidopyrinium-methanesulphate natrium [German], 1-Phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate sodium, 4-Methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone sodium methanesulfonate, Dipyrone (BAN), Sodium 1-phenyl-2,3-dimethyl-4-methylaminopyrazolon-N-methanesulfonate, Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylamino methanesulfonate, 1-Phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonic acid sodium, CCRIS 272, Sodium 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone 4-methanesulfonate, Fenildimetil-pirazolon-metilaminometansolfonato sodico, Dipyrone (anhydrous), sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate, Metamizol sodium, Methanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)-, sodium salt, NCGC00017049-01, Fenildimetil-pirazolon-metilaminometansolfonato sodico [Italian], Methanesulfonic acid, (antipyrinylmethylamino)-, monosodium salt, DSSTox_CID_543, NSC 73205, 1-Phenyl-2,3-dimethyl-4-methylamino-5-pyrazolon-N-methanesulfonsaeuren natrium, 1-Phenyl-2,3-dimethyl-4-methylamino-5-pyrazolon-N-methanesulfonsaeuren natrium [German], DSSTox_RID_75651, DSSTox_GSID_20543, Dipyronium, Normelubrine, Algopyrin, Biopyrin, Prodolina, Metamizol sodico, Metamizolo sodico, Dipyrone anhydrous, Methamizole sodium, CAS-68-89-3, Sulpyrine [JAN], Sodium (antipyrinylmethylamino)methanesulfonate monohydrate, Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt, Sodium ((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino)methanesulfonate, Sodium ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)methanesulphonate, Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonate, (Antipyrinylmethylamino)methanesulfonic acid sodium salt monohydrate, Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt, monohydrate, Dipyrone [USAN:JAN], Methylmelubrine, dipyrone sodium, Noramidopyrine Methanesulfonate, Dipyrone,(S), Vetalgin (TN), [(2,3-dimethyl-5-oxo-1-phenyl(3-pyrazolin-4-yl))methylamino]methanesulfonic ac id, sodium salt, Prestwick_987, AC1LAWRC, Metamizole sodium [INN], Methanesulfonic acid, ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)-, sodium salt, monohydrate, D06JRD, D0K9LD, Epitope ID:124939, C13H16N3NaO4S, SCHEMBL24996, ARONIS24557, C13H16N3O4S.Na, SPECTRUM1503298, CHEMBL487894, DTXSID8020543, Metamizol sodico [INN-Spanish], CTK8F9257, HMS501P16, BBC/728, DJGAAPFSPWAYTJ-UHFFFAOYSA-M, MolPort-001-794-652, HMS1570O07, HMS1922A06, HMS2093C17, HMS2097O07, HMS3714O07, KS-000048IL, ZX-AS004928, Tox21_110759, Tox21_200497, CCG-39331, SBB058149, AKOS015904648, Noramidopyrine Methanesulphonate Sodium, Tox21_110759_1, API0002418, DB04817, LS-7367, NCGC00017049-02, NCGC00017049-03, NCGC00095040-01, NCGC00095040-02, NCGC00178220-05, NCGC00258051-01, AN-23779, LS-90303, CAS-5907-38-0, AB1009522, FT-0081369, FT-0602853, ST51014992, D08190, I14-16785, potassium [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)(methyl)amino]methanesulfonate, sodium [(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-methyl-amino]methanesulfonate, sodium [(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-methylamino]methanesulfonate, sodium;[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-methylamino]methanesulfonate, 57904-20-8, Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl) methylamino]methanesulfonate; Metamizole sodium

ID: 462

InChIKey: DJHCCTTVDRAMEH-DUUJBDRPSA-N
SMILES: CCC(=O)OCC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2[C@@H](CC4=CC(=O)C=C[C@]34C)Cl)O)C)C)OC(=O)CC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 636374
synonyms found at PubChem are:
ALCLOMETASONE DIPROPIONATE, Aclovate, 66734-13-2, Delonal, Vaderm, Aclosone, Modrasone, Legederm, Almeta, Sch 22219, Alclomethasone-17,21-dipropionate, UNII-S56PQL4N1V, S56PQL4N1V, Sch-22219, CHEBI:31184, CCRIS 1927, EINECS 266-464-3, BRN 2317658, (7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, (7alpha,11beta,16alpha)-7-chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate, NCGC00016984-01, 7alpha-Chloro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, Perderm (Salt/Mix), Modrasone (Salt/Mix), Alclometasone dipropionate [USAN:USP:JAN], AC1LCS4K, SCHEMBL6833, DSSTox_CID_25535, DSSTox_RID_80937, Ppropionic acid alclometasone, DSSTox_GSID_45535, CHEMBL1200989, DTXSID6045535, DJHCCTTVDRAMEH-DUUJBDRPSA-N, 7alpha-Chloro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate), Pregna-1,4-diene-3,20-dione, 7-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (7alpha,11beta,16alpha)-, ZINC4172330, Tox21_110726, Alclometasone dipropionate (JAN/USP), AKOS015896564, AC-3530, AN-12868, AX8046352, CAS-66734-13-2, D01820, 734A132, I06-2403, Q-101392, [2-[(7R,8S,9S,10R,11S,13S,14S,16R,17R)-7-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate, [2-[(7R,8S,9S,10R,11S,13S,14S,16R,17R)-7-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate, 7-Chloro-11-hydroxy-16-methyl-3,20-dioxo-17-(propionyloxy)pregna-1,4-dien-21-yl propionate, (7.alpha.,11.beta.,16.alpha.)- #, 7-Chloro-17,21-dipropionate-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, (7.alpha.,11.beta.,16.alpha.)-, 7.alpha.-Chloro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, Pregna-1,4-diene-3,20-dione, 7-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (7.alpha.,11.beta.,16.alpha.)-

ID: 463

InChIKey: DKGZKTPJOSAWFA-UHFFFAOYSA-N
SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCC(=O)C4=CC=C(C=C4)F

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5265
synonyms found at PubChem are:
spiperone, Spiroperidol, Spiropitan, 749-02-0, Espiperona, Spiperonum, [3H]spiperone, [3H]-spiperone, Spiroperidone, R 5147, Spiperonum [INN-Latin], Espiperona [INN-Spanish], E 525, UNII-4X6E73CJ0Q, NSC 170983, MLS000028615, Spiperone [USAN:INN:BAN:JAN], 8-(3-(p-Fluorobenzoyl)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one, 8-(3-p-Fluorobenzoyl-1-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decane, 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, EINECS 212-024-0, BRN 0632204, SMR000058674, 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-, 4X6E73CJ0Q, CHEBI:9233, CHEMBL267930, C23H26FN3O2, DKGZKTPJOSAWFA-UHFFFAOYSA-N, Butyrophenone, 4'-fluoro-4-(4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl)-, NSC170983, NCGC00015964-09, CAS-749-02-0, 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-1-phenyl-, 4-Phenyl-8-[3-(4-fluorobenzoyl)propyl]-1-oxo-2,4,8-triazaspiro[4,5]decane, 8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, R-5147, DSSTox_CID_25205, DSSTox_RID_80749, DSSTox_GSID_45205, Spiroperone, 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorobenzoyl)propyl]-1-phenyl-, 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-, 8-[4-(4-fluorophenyl)-4-oxobutyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one, SR-01000000261, Spiperone, solid, Spiropitan (TN), Prestwick_624, [3H]-Spiroperidol, Spectrum_001143, Tocris-0995, Spiperone (JAN/USAN), AC1L1JYU, regid855701, Opera_ID_1551, Prestwick0_000288, Prestwick1_000288, Prestwick2_000288, Prestwick3_000288, Spectrum2_001426, Spectrum3_001460, Spectrum4_000451, Spectrum5_000987, Lopac-S-7395, R 5147, Spiroperidol, D04TIH, D05EQG, GTPL99, cid_5265, Lopac0_001069, REGID_for_CID_5265, BSPBio_000196, BSPBio_002959, KBioGR_000862, KBioSS_001623, MLS001076321, DivK1c_000566, SCHEMBL116031, SPECTRUM1501152, SPBio_001532, SPBio_002415, BPBio1_000216, GTPL3300, DTXSID5045205, BDBM21397, HMS501M08, KBio1_000566, KBio2_001623, KBio2_004191, KBio2_006759, KBio3_002459, MolPort-003-666-371, NINDS_000566, HMS1568J18, HMS1921L09, HMS2089E16, HMS2092H17, HMS2095J18, HMS2235E11, HMS3371L01, HMS3712J18, Pharmakon1600-01501152, ZINC643233, Tox21_110269, BN0500, CCG-38975, MFCD00055099, NSC757864, AKOS024282958, Tox21_110269_1, API0004229, MCULE-7534168791, NSC-170983, NSC-757864, IDI1_000566, NCGC00015964-01, NCGC00015964-02, NCGC00015964-03, NCGC00015964-04, NCGC00015964-05, NCGC00015964-06, NCGC00015964-07, NCGC00015964-08, NCGC00015964-10, NCGC00015964-11, NCGC00015964-12, NCGC00015964-13, NCGC00015964-17, NCGC00016536-01, NCGC00022260-02, NCGC00022260-04, NCGC00022260-05, NCGC00022260-06, NCGC00022260-07, ST059306, SBI-0051039.P003, LS-154780, AB00052224, FT-0674639, D01051, 36693-EP2272537A2, 36693-EP2311801A1, 36693-EP2311802A1, 36693-EP2311803A1, 36693-EP2371814A1, AB00052224-15, AB00052224_16, L000569, SR-01000000261-5, SR-01000000261-8, BRD-K55468218-001-05-5, BRD-K55468218-003-01-0, WLN: T6N DXTJ A3VR DF& D-& CT5MVXN EHJ DR, 8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,8-triazaspiro[4.5]decan-4-one, 1,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorobenzoyl)propyl]-1-phenyl-, 1,8-Triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-, 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxo-butyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one, 1-(4-Fluorophenyl)-4-(4-hydroxy-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-en-8-yl)-1-butanone #

ID: 464

InChIKey: DKKJNZYHGRUXBS-BQYQJAHWSA-N
SMILES: COC1=CC(=O)OC(=C1)/C=C/C2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5273621
synonyms found at PubChem are:
Desmethoxyyangonin, 5,6-Dehydrokawain, Demethoxyyangonin, 15345-89-8, Desmethoxy Yangonin, UNII-F2MBQ8QRUN, (E)-4-Methoxy-6-styryl-2H-pyran-2-one, 4-Methoxy-6-styryl-2H-pyran-2-one, 5,6-Dehydrokavain, NSC 112161, F2MBQ8QRUN, trans-5,6-Dehydrokawain, (E)-4-Methoxy-6-(2-phenylethenyl)-2H-pyran-2-one, CHEBI:1995, 1952-41-6, 2H-Pyran-2-one, 4-methoxy-6-styryl-, (E)-, 4-methoxy-6-(2-phenylethenyl)-2h-pyran-2-one, 4-methoxy-6-[(E)-2-phenylethenyl]pyran-2-one, DMY, 2H-Pyran-2-one, 4-methoxy-6-(2-phenylethenyl)-, (E)-, 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-phenylethenyl]-, 2H-Pyran-2-one, 4-methoxy-6-(2-phenylethenyl)-, (E)- (9CI), 5,6-Dihydro-5-hydroxy-6-methyl-2H-pyran-2-one, 4-methoxy-6-[(E)-2-phenylvinyl]-2H-pyran-2-one, 4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one, 26531-51-1, CCRIS 9369, Desmethoxyangonin, 5,6-Dehydrokawin, Yangonin, demethoxy-, AC1NRVA2, DSSTox_CID_13390, DSSTox_RID_79070, DSSTox_GSID_33390, SCHEMBL236641, AC1Q69K8, CHEMBL254218, DTXSID4033390, DKKJNZYHGRUXBS-BQYQJAHWSA-N, MolPort-016-638-410, ZINC899562, HY-N0918, NSC68686, Tox21_200296, 8029AH, 9332AF, NSC 68686, NSC-68686, NSC112161, AKOS015896811, Desmethoxyyangonin, analytical standard, CCG-208562, CS-4242, MCULE-7908006221, NSC-112161, 4-methoxy-6-[(E)-styryl]pyran-2-one, NCGC00091904-01, NCGC00091904-02, NCGC00257850-01, CC-20905, ZB015163, 4-Methoxy-6-styryl-(E)-2H-Pyran-2-one, CAS-15345-89-8, KB-146069, LS-127466, 4-methoxy-6-[(E)-2-phenylvinyl]-2-pyranone, C09925, 4-methoxy-6-[(E)-2-phenylethenyl]-2-pyranone, 345D898, A809430, SR-05000002195, 2H-Pyran-2-one, 4-methoxy-6-(2-phenylethenyl)-, I07-0159, SR-05000002195-2, 4-Methoxy-6-(2-phenylethenyl)-(E)-2H-Pyran-2-one, 4-Methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one, 2H-Pyran-2-one, 4-methoxy-6-[(E)-2-phenylethenyl]-, NCGC00091904-06!4-methoxy-6-[(E)-2-phenylethenyl]pyran-2-one

ID: 465

InChIKey: DKYWVDODHFEZIM-UHFFFAOYSA-N
SMILES: CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3825
synonyms found at PubChem are:
ketoprofen, 22071-15-4, 2-(3-Benzoylphenyl)propanoic acid, Orudis, 2-(3-Benzoylphenyl)propionic acid, Ketoprofene, m-Benzoylhydratropic acid, Profenid, Actron, Oruvail, 3-Benzoylhydratropic acid, Alrheumat, Alrheumun, Capisten, Epatec, Aneol, Orudis (TN), Orudis KT, Ketoprofeno, Ketoprophene, Alrheumum, Kefenid, Ketopron, Menamin, Meprofen, Orugesic, Oscorel, Fastum, Lertus, Toprec, Toprek, Dexal, racemic-Ketoprofen, Iso-K, RP-19583, 2-[3-(phenylcarbonyl)phenyl]propanoic acid, Benzoylhydratropic Acid, Ketoprofenum, RP 19583, 2-(m-Benzoylphenyl)propionic acid, Ketoprofene [INN-French], Ketoprofenum [INN-Latin], Racemic ketoprofen, Ketoprofeno [INN-Spanish], 3-BENZOYL-ALPHA-METHYLBENZENEACETIC ACID, Ketoprofen (+-), RU 4733, Ketoprofen (Actron), CHEBI:6128, (+-)-m-Benzoylhydratropic acid, Benzeneacetic acid, 3-benzoyl-alpha-methyl-, 2-[3-Benzoylphenyl]propionic acid, Benzeneacetic acid, 3-benzoyl-.alpha.-methyl-, CHEMBL571, Propionic acid, 2-(3-benzoylphenyl)-, 19583 RP, L'Acide (benzoyl-3-phenyl)-2-propionique, MLS000079024, CCRIS 4508, (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid, DKYWVDODHFEZIM-UHFFFAOYSA-N, Ketoprofen [USAN:INN:BAN:JAN], Acide (benzoyl-3-phenyl)-2-propionique [French], EINECS 244-759-8, 2-[3-(benzoyl)phenyl]propanoic acid, 22161-86-0, Hydratropic acid, m-benzoyl-, (+-)-, Acide (benzoyl-3-phenyl)-2-propionique, SMR000040181, DSSTox_CID_771, K 1751, DSSTox_RID_75783, DSSTox_GSID_20771, Benzeneacetic acid, 3-benzoyl-alpha-methyl-, (+-)-, SR-01000075949, ketoprophen, Ketoflam, (+) ketoprofen, Ketospray (TN), Ketoprofene (TN), NCGC00016757-01, Ketoflam (TN), Ketoprofen ,(S), Ketoprofenas (TN), Ketoprofenum (TN), Prestwick_617, Arthril (TN), Ketomex (TN), Ketonal (TN), Ketorin (TN), Lasonil (TN), Oruvail (TN), Bi-Profnid (TN), Fastum Gel (TN), CAS-22071-15-4, Fastum (TN), Keto (TN), Spectrum_001309, Opera_ID_509, Oki (TN), Zon (TN), 19,583 RP, AC1L1GST, AC1Q1LGA, Prestwick0_000219, Prestwick1_000219, Prestwick2_000219, Prestwick3_000219, Spectrum2_000956, Spectrum3_001479, Spectrum4_000028, Spectrum5_001254, m-benzoyl-hydratropic acid, RP, 19,583, D0W9WF, Epitope ID:131783, SCHEMBL2896, Lopac0_000686, Oprea1_117113, BSPBio_000237, BSPBio_003037, KBioGR_000435, KBioSS_001789, MLS000028446, MLS001201752, MLS001306444, MLS002548889, MLS006011967, BIDD:GT0443, DivK1c_000598, SPECTRUM1501215, SPBio_000952, SPBio_002158, BPBio1_000261, GTPL4795, Ketoprofen (JP15/USP/INN), Ketoprofen (JP17/USP/INN), Ketoprofen, >=98% (TLC), DTXSID6020771, CTK8F2159, DKYWVDODHFEZIM-UHFFFAOYSA-, HMS501N20, KBio1_000598, KBio2_001789, KBio2_004357, KBio2_006925, KBio3_002537, KS-00000GGJ, (+-)-m-Benzoyl-hydratropic acid, (+/-)-m-Benzoylhydratropic acid, MolPort-001-684-346, NINDS_000598, HMS1568L19, HMS1921B12, HMS2089B16, HMS2092L19, HMS2095L19, HMS2234H16, HMS3259I05, HMS3262I13, HMS3372M08, HMS3373G09, HMS3649N10, HMS3655C15, HMS3712L19, Pharmakon1600-01501215, BCP23428, HY-B0227, 2-(3'-benzoylphenyl)propionic acid, 2-(3-benzoylphenyl) propionic acid, 2-(3-benzoylphenyl)-propionic acid, alpha(3-benzoylphenyl)propionic acid, Tox21_110594, Tox21_200847, Tox21_500686, (.+/-.)-m-Benzoylhydratropic acid, 2-(3-benzoylphenyl) propionoic acid, alpha-(m-benzoylphenyl)propionic acid, BDBM50022271, CCG-39685, MFCD00055790, NSC758144, s1645, SBB063946, STL450995, 2-(3-Benzoylphenyl)propanoic acid #, alpha-(3-benzoylphenyl)propionic acid, AKOS007930512, alpha-(m-benzoylphenyl) propionic acid, Tox21_110594_1, AC-1486, BCP9000810, CS-2175, DB01009, Ketoprofen [USAN:USP:INN:BAN:JAN], KS-5031, LP00686, LS-7470, MCULE-9740144074, NC00459, NSC-758144, IDI1_000598, TRA-0188004, (rs)-2-(3-benzoylphenyl)propanoic acid, Benzeneacetic acid, 3-benzoyl-?-methyl-, NCGC00015578-02, NCGC00015578-03, NCGC00015578-04, NCGC00015578-05, NCGC00015578-07, NCGC00015578-08, NCGC00015578-10, NCGC00015578-12, NCGC00094043-01, NCGC00094043-02, NCGC00094043-03, NCGC00094043-04, NCGC00258401-01, NCGC00261371-01, AN-14915, BC201672, BR-47496, CPD000040181, LS-28621, Orudis;Oruvail;Ketoflam;Orudis KT;Actron, SAM002264620, SC-17621, 3-Benzoyl-.alpha.-methylbenzeneacetic acid, BCP0726000302, SBI-0050664.P003, (+/-)-2-(3-Benzoylphenyl)propionic acid, AB2000190, KB-162618, L''Acide (benzoyl-3-phenyl)-2-propionique, ST2409293, UNM-0000306100, AB00052249, AM20060549, EU-0100686, FT-0082352, FT-0602834, K0038, Ketoprofen, meets USP testing specifications, Orudis, Profenid, Dexal, Keduril, Ketofen,, R.P. 19583, R.P. 19,583, BIM-0050664.0001, C01716, D00132, Ketoprofen, VETRANAL(TM), analytical standard, M-7468, AB00052249-17, AB00052249-19, AB00052249-20, AB00052249_21, AB00052249_22, 071K154, A815896, Orudis, Oruvail, Ketoflam, Orudis KT, Ketoprofen, I01-3439, Q-201268, SR-01000075949-1, SR-01000075949-6, SR-01000075949-9, (.+/-.)-3-Benzoyl-.alpha.-methylbenzeneacetic acid, Benzeneacetic acid, 3-benzoyl-alpha-methyl-, (+/-), BRD-A97739905-001-05-9, BRD-A97739905-001-15-8, SR-01000075949-18, F2173-0960, Z1695709452, Ketoprofen, British Pharmacopoeia (BP) Reference Standard, Ketoprofen, European Pharmacopoeia (EP) Reference Standard, Ketoprofen, United States Pharmacopeia (USP) Reference Standard, Ketoprofen, Pharmaceutical Secondary Standard; Certified Reference Material, 154907-35-4, 172964-50-0, InChI=1/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

ID: 466

InChIKey: DLCJNIBLOSKIQW-UHFFFAOYSA-N
SMILES: COC1=C2C(=C3C(=C1)C=CC(=O)O3)C=CO2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 108104
synonyms found at PubChem are:
Sphondin, 483-66-9, 6-Methoxyfuro[2,3-h]chromen-2-one, CHEBI:81486, 2H-Furo(2,3-h)-1-benzopyran-2-one, 6-methoxy-, 6-Methoxy-2H-furo[2,3-H]chromen-2-one, Sfondin, Spectrum_000598, SpecPlus_000144, Spectrum2_001759, Spectrum3_001238, Spectrum4_001600, Spectrum5_000320, AC1L33CH, 6-Methoxy-2H-furo(2,3-h)-1-benzopyran-2-one, BSPBio_002716, KBioGR_002220, KBioSS_001078, SPECTRUM300005, MLS000574845, DivK1c_006240, SPBio_001898, SCHEMBL9794931, CHEMBL1452868, CTK1D6743, KBio1_001184, KBio2_001078, KBio2_003646, KBio2_006214, KBio3_002216, DTXSID20197481, DLCJNIBLOSKIQW-UHFFFAOYSA-N, MolPort-000-882-157, HMS2218E05, HMS3340O03, ZINC3197732, CCG-38810, STK691970, 4-methoxyfurano[2,3-h]chromen-8-one, AKOS000277842, MCULE-1142431458, SDCCGMLS-0066509.P001, NCGC00095567-01, NCGC00095567-02, NCGC00178511-01, 4CN-1365, SMR000156215, ST097615, W1276, 6-Methoxy-2H-furo[2,3-H]chromen-2-one #, VU0243951-5, SR-01000711830, SR-01000711830-2, BRD-K33260002-001-02-0, BRD-K33260002-001-06-1

ID: 467

InChIKey: DLCVFIMWFKVRTM-UHFFFAOYSA-N
SMILES: COC1=CC(=O)C(=CC1=O)C(C=C)C2=CC=C(C=C2)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3950721
synonyms found at PubChem are:
DALBERGIONE, 4-METHOXY-4'-HYDROXY-, KBio2_005719, AC1MZQJO, Spectrum_000123, SpecPlus_000157, Spectrum2_000562, Spectrum3_000193, Spectrum4_001944, Spectrum5_000659, BSPBio_001745, KBioGR_002350, KBioSS_000583, SPECTRUM200798, DivK1c_006253, SPBio_000344, CHEMBL1374504, KBio1_001197, KBio2_000583, KBio2_003151, KBio3_001245, CCG-38728, SDCCGMLS-0066446.P001, NCGC00095491-01, NCGC00095491-02, NCGC00095491-03, SR-05000002517, SR-05000002517-1, 2-[1-(4-hydroxyphenyl)-2-propenyl]-5-methoxy-2,5-cyclohexadiene-1,4-dione, 2-[1-(4-hydroxyphenyl)prop-2-enyl]-5-methoxycyclohexa-2,5-diene-1,4-dione

ID: 468

InChIKey: DLFVBJFMPXGRIB-UHFFFAOYSA-N
SMILES: CC(=O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 178
synonyms found at PubChem are:
acetamide, 60-35-5, Ethanamide, Acetic acid amide, Methanecarboxamide, Acetimidic acid, Amide C2, Ethanimidic acid, acetamid, Amid kyseliny octove, Caswell No. 003H, Acetimidic acid (VAN), CCRIS 2, NCI-C02108, acetoamide, HSDB 4006, CH3CONH2, UNII-8XOE1JSO29, Amid kyseliny octove [Czech], AI3-02060, EINECS 200-473-5, NSC 25945, BRN 1071207, 8XOE1JSO29, CHEBI:27856, DLFVBJFMPXGRIB-UHFFFAOYSA-N, acetylamine, Essigsaeureamid, Ethanamid, imidoacetic acid, N-Methylformamde, DSSTox_CID_5, Acetamide, >=98%, Ethanimidic acid (9CI), ACETAMIDE, REAGENT, Lopac-A-0500, ACMC-1AWJ5, bmse000825, bmse000895, D0S6KY, EC 200-473-5, AC1L18NI, AC1Q2B5A, Acetamide, sublimed, 99%, WLN: ZV1, DSSTox_RID_75317, Acetamide, ~99% (GC), DSSTox_GSID_20005, Lopac0_000003, Acetamide, 99% 250g, 4-02-00-00399 (Beilstein Handbook Reference), KSC353G6F, MLS002153504, Acetamide, analytical standard, BIDD:ER0566, CHEMBL16081, GTPL4661, DTXSID7020005, Acetamide, crystalline, >=99%, CHEBI:49028, CTK1A5953, CTK2F3362, Acetamide, >=98.0% (GC), Acetamide, >=99.0% (GC), MolPort-001-779-697, HMS3260A07, Acetamide (6CI,7CI,8CI,9CI), BCP26153, NSC25945, STR01066, ZINC8034818, Tox21_300776, Tox21_500003, ANW-20374, MFCD00008023, NSC-25945, STL283915, AKOS000118788, AKOS015917387, CCG-204099, DB02736, LP00003, LS-1431, MCULE-9280264861, RL04274, RTR-037243, TRA0053610, CAS-60-35-5, KS-00000G57, NCGC00015030-01, NCGC00015030-02, NCGC00015030-03, NCGC00015030-04, NCGC00015030-05, NCGC00093530-01, NCGC00093530-02, NCGC00254680-01, NCGC00260688-01, 4CN-0956, 9015-82-1, AN-23637, KB-47044, SC-18410, SMR000326670, AB1002187, ST2412615, TR-037243, A0007, EU-0100003, FT-0603458, FT-0621721, FT-0621725, FT-0625737, 9745-EP2269990A1, 9745-EP2275407A1, 9745-EP2275469A1, 9745-EP2287940A1, 9745-EP2289890A1, 9745-EP2289965A1, 9745-EP2295402A2, 9745-EP2295550A2, 9745-EP2298744A2, 9745-EP2298749A1, 9745-EP2298761A1, 9745-EP2298776A1, 9745-EP2298777A2, 9745-EP2298828A1, 9745-EP2301918A1, 9745-EP2301933A1, 9745-EP2301983A1, 9745-EP2305640A2, 9745-EP2305648A1, 9745-EP2305687A1, 9745-EP2308872A1, 9745-EP2308873A1, 9745-EP2308880A1, 9745-EP2311808A1, 9745-EP2311827A1, 9745-EP2311829A1, 9745-EP2311842A2, 9745-EP2314593A1, 9745-EP2316829A1, 9745-EP2316831A1, 9745-EP2316834A1, A 0500, C06244, 25464-EP2284166A1, 25464-EP2314580A1, 25704-EP2298729A1, 25704-EP2315303A1, A832706, SR-01000076247, I14-9593, J-523678, S14-1087, SR-01000076247-1, Acetamide, zone-refined, purified by sublimation, 99%, InChI=1/C2H5NO/c1-2(3)4/h1H3,(H2,3,4, F1908-0077, ACETAMIDE (SEE ALSO N-(4-FLUORENYL)ACETAMIDE 28322-02-3), 02U, 27595-75-1, CNM

ID: 469

InChIKey: DLGOEMSEDOSKAD-UHFFFAOYSA-N
SMILES: C(CCl)NC(=O)N(CCCl)N=O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2578
synonyms found at PubChem are:
carmustine, 154-93-8, 1,3-Bis(2-chloroethyl)-1-nitrosourea, BCNU, Carmustin, Nitrumon, Carmubris, Gliadel, BiCNU, Bi CNU, Bischlorethylnitrosurea, Bischlorethylnitrosourea, Carmustina, Carmustinum, Becenum, Becenun, Bischloroethyl nitrosourea, N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA, Bis(2-chloroethyl)nitrosourea, Urea, N,N'-bis(2-chloroethyl)-N-nitroso-, Gliadel Wafer, Bischloroethylnitrosourea, FDA 0345, SRI 1720, 1,3-Bis(2-chloroethyl)nitrosourea, BiCNU (TN), Carmustinum [INN-Latin], Carmustina [INN-Spanish], DTI 015, NCI-C04773, SK 27702, FIVB, NSC-409962, Bis(2-chloroethyl)1-nitrosourea, Bis(chloroethyl)nitrosourea, Bis-N,N'-(chloroethyl)nitrosourea, CCRIS 810, Carmustine [USAN:INN:BAN], NSC 409962, UNII-U68WG3173Y, carmustine in ethanol, 1,3-Bis(beta-chloroethyl)-1-nitrosourea, BCNU [Chloroethyl nitrosoureas], EINECS 205-838-2, NSC409962, CHEMBL513, 1,3-bis(2-chloroethyl)-3-nitrosourea, BRN 2049744, 1,3-bis(2-chloroethyl)-1-nitroso-urea, AI3-52216, CHEBI:3423, Urea, 1,3-bis(2-chloroethyl)-1-nitroso-, DLGOEMSEDOSKAD-UHFFFAOYSA-N, U68WG3173Y, Bischloroethyl nitrosourea [Chloroethyl nitrosoureas], NCGC00015204-05, 1,3-Bis(.beta.-chloroethyl)-1-nitrosourea, 1,3-BIS(CHLOROETHYL)-1-NITROSOUREA, DSSTox_CID_2743, C 0400, DSSTox_RID_76712, DSSTox_GSID_22743, CAS-154-93-8, SR-01000075736, C5H9Cl2N3O2, Carustine, HSDB 7761, Carmustine [USAN:USP:INN:BAN], Carmustine(BiCNU), Prestwick_997, Gliadel (TN), Carmustine(BiCNU)/, Gliadel (MGI Pharm), Spectrum_000265, Carmustine, >=98%, AC1L1DZQ, Carmustine (USAN/INN), Spectrum4_000888, Spectrum5_000920, Lopac-C-0400, WLN: ONN2GVM2G, D0S9UT, SCHEMBL4503, Lopac0_000188, KBioGR_001296, KBioSS_000745, C5H11Cl2N3O2, MLS001333962, Carmustine (JAN/USAN/INN), DivK1c_000835, GTPL6800, DTXSID8022743, CTK8B8775, HMS502J17, KBio1_000835, KBio2_000745, KBio2_003313, KBio2_005881, AOB6824, MolPort-003-665-505, NINDS_000835, HMS2092J22, HMS2230I05, HMS3260F17, HMS3369D17, Pharmakon1600-01503110, BCP27690, ZINC3830387, Tox21_110097, Tox21_500188, ABP000292, ANW-61236, BDBM50015950, CCG-39925, LS-890, MFCD00057706, NSC758392, STK624770, AKOS005558013, Tox21_110097_1, AN-1123, BCP9000490, CS-2935, DB00262, LP00188, MCULE-3131772074, NSC-758392, IDI1_000835, Urea,3-bis(2-chloroethyl)-1-nitroso-, NCGC00015204-01, NCGC00015204-02, NCGC00015204-03, NCGC00015204-04, NCGC00015204-06, NCGC00015204-07, NCGC00015204-08, NCGC00015204-09, NCGC00093665-01, NCGC00093665-02, NCGC00093665-03, NCGC00093665-04, NCGC00260873-01, Urea,N'-bis(2-chloroethyl)-N-nitroso-, 4CA-0349, AC-24196, AS-12106, HY-13585, N,N''-Bis(2-chloroethyl)-N-nitrosourea, NCI60_003931, SC-17305, SMR000058426, 1,3-Bis(beta.-chloroethyl)-1-nitrosourea, SBI-0050176.P003, AB0011283, AB2000140, Gliadel;BCNU;NSC-409962;Becenun;BiCNU, KB-216399, TC-149981, EU-0100188, FT-0083563, FT-0602937, ST24036755, BCNU; 1,3-Bis(2-chloroethyl)-1-nitrosourea, C06873, D00254, 13167-EP2270014A1, 13167-EP2272827A1, 13167-EP2272832A1, 13167-EP2275420A1, 13167-EP2277876A1, 13167-EP2292614A1, 13167-EP2295055A2, 13167-EP2295416A2, 13167-EP2295426A1, 13167-EP2295427A1, 13167-EP2298748A2, 13167-EP2298764A1, 13167-EP2298765A1, 13167-EP2298768A1, 13167-EP2298778A1, 13167-EP2305642A2, 13167-EP2308861A1, 13167-EP2311453A1, 13167-EP2311808A1, 13167-EP2311825A1, 13167-EP2311829A1, 13167-EP2311842A2, 13167-EP2314590A1, 13167-EP2316832A1, 13167-EP2316833A1, 13167-EP2316834A1, 13167-EP2374454A1, 15164-EP2272827A1, 15164-EP2316832A1, 15164-EP2316833A1, AB00052431-07, AB00052431_08, 154C938, A809590, Gliadel, BCNU, NSC-409962, Becenun, Carmustine, SR-01000075736-1, SR-01000075736-3, W-108025, I14-11976, Z1563145982, Carmustine, United States Pharmacopeia (USP) Reference Standard, 1-(2-Chloroethyl)-1-([(2-chloroethyl)amino]carbonyl)-2-oxohydrazine #, 1159711-15-5, 1191292-23-5

ID: 470

InChIKey: DLIKSSGEMUFQOK-SFTVRKLSSA-N
SMILES: C1[C@H](OC2=CC(=CC(=C2C1=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C4=CC=C(C=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 92794
synonyms found at PubChem are:
Prunin, Naringenin-7-O-glucoside, 529-55-5, Naringenin 7-O-beta-D-glucoside, CHEBI:28327, (S)-7-(beta-D-Glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl beta-D-glucopyranoside, PRUNIN PROTEIN, PRUNUS, (-)-Naringenin 7-beta-D-glucoside, EINECS 208-464-8, NSC 135064, AC1L3OUJ, AC1Q6NLA, (s)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl b-d-glucopyranoside, SCHEMBL318229, CHEMBL469654, MolPort-006-069-106, Naringenin - 7 - O - glucoside, ZINC4097895, MFCD00210548, Prunin, >=95% (LC/MS-ELSD), API0003517, CCG-208407, NCGC00163599-01, ST24035510, W2798, C09099, SR-05000013703, SR-05000013703-1, (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one, (S)-5-Hydroxy-2-(4-hydroxy-phenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydropyran-2-yloxy)-chroman-4-one, (S)-5-hydroxy-2-(4-hydroxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)chroman-4-one, 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-

ID: 471

InChIKey: DLLKDLFPBARGCC-UHFFFAOYSA-N
SMILES: CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CSC(=N3)NC4=CC=CC=C4OC

biological descriptors:

CFTR relevance: CFTR corrector

Category:
Influence on CFTR function enhances CFTR function
Order of interaction unknown
subcellular compartment unknown

reference list:

"AS Verkman" "K Du" "O Zegarra-Moran" "E Caci" "LJ Galietta" "GL Lukacs" "N Pedemonte"

CID is 1117191
synonyms found at PubChem are:
N-[2-(2-Methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide, MLS000561133, AC1LLWE7, Oprea1_308767, Oprea1_707648, SCHEMBL837888, CHEMBL1306491, MolPort-000-690-613, HMS2197B19, HMS3331I07, ZINC853329, AKOS000565400, MCULE-7647996207, BAS 01247205, SMR000156158, SR-01000477242, SR-01000477242-1, N-(2-(2-Methoxyphenylamino)-4'-methyl-4,5'-bithiazol-2'-yl)benzamide, N-[5-[2-(2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide

ID: 472

InChIKey: DLNKOYKMWOXYQA-VXNVDRBHSA-N
SMILES: C[C@H]([C@H](C1=CC=CC=C1)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 26934
synonyms found at PubChem are:
Norephedrine, phenylpropanolamine, Rhindecon, dl-Norephedrine, (+)-Norephedrine, Dexatrim, Propagest, Mucron, d-Norephedrine, Super Odrinex, Propadrine, (+-)-Norephedrin, Phenyldrine, Phenylfenesin, Acutrim, Codimal, Contuss, Exponcit, Guaipax, Myminic, Partuss, Phenoxine, Snaplets, Cathinum [INN-Latin], Despec, Gentab, Rhymed, Conex, Nolex, Vanex, Dura-Vent, Ami-Tex, Katine, psi-Norephedrine, 14838-15-4, (1S,2R)-2-amino-1-phenylpropan-1-ol, dl-1-Phenyl-2-aminopropanol-1, Fenilpropanolamina, (+/-)-Norephedrin, UNII-7875H6443P, 1r,2s-phenylpropylamine, Phenylpropanolaminum, d-Norpseudoephedrine, Cathine [INN], d-Nor-psi-ephedrine, (+-)-Norephedrine, dl-Phenylpropanolamine, dl-2-Amino-1-hydroxy-1-phenylpropane, CHEBI:36, Cathina, Cathinum, Minusine, Naldecon, (+-)-Phenylpropanolamine, Norpseudoephedrine, NSC9920, Phenylpropanolamina, DLNKOYKMWOXYQA-VXNVDRBHSA-N, 37577-28-9, l-Nor-psi-ephedrin, l-Nor-psi-ephedrine, D-(+)-Norephedrine, Cathina [INN-Spanish], 7875H6443P, Phenylpropanolamine (VAN), PPA [Nasal Decongestant], C9H13NO, Fugoa, Phenylpropanolamine [INN:BAN], Fugoa Depot, HSDB 6485, Phenylpropanolaminum [INN-Latin], Phenylpropanolamina [INN-Spanish], NSC 9920, EINECS 207-754-1, EINECS 211-850-9, EINECS 238-900-2, Fansia (TN), dl-alpha-(1-Aminoethyl)benzyl alcohol, Benzyl alcohol, alpha-(1-aminoethyl)-, beta-hydroxyamphetamine, L-(-)-Norephedrine, BRN 2802895, BRN 3196918, dl-alpha-Hydroxy-beta-aminopropylbenzene, (+/-)-Norephedrine, TAVIST-D, ULR, Prestwick_388, Benzenemethanol, alpha-(1-aminoethyl)-, (R*,S*)-, DEA No. 1230, Norephedrin, Fansia, Norephedrine, (.+-.)-, Phenylpropanolamin, Propalin (TN), Proin (TN), L-Phenyl Propanolamine, SpecPlus_000934, (.+-.)-Norephedrine, (R*,S*)-(1)-alpha-(1-Aminoethyl)benzyl alcohol, Prestwick3_000324, Spectrum2_000516, Spectrum3_001706, Spectrum4_001685, Spectrum5_000330, DEA Code 1225, D04KKT, D09JXM, WLN: ZY1&YQR, AC1L1C6K, Benzenemethanol, alpha-((1S)-1-aminoethyl)-, (alphaS)-, Constituent of "Khat" plant, SCHEMBL26905, (.+-.)-Phenylpropanolamine, BSPBio_000327, BSPBio_003292, KBioGR_001950, Benzenemethanol, alpha-((1R)-1-aminoethyl)-, (alphaS)-rel-, BIDD:GT0376, DivK1c_007030, SPECTRUM2300253, SPBio_000471, BPBio1_000361, ZINC1930, CHEMBL2092846, DTXSID4023466, KBio1_001974, KBio3_002512, Benzenemethanol, alpha-(1-aminoethyl)-, (R*,S*)-(+-)-, Benzenemethanol, alpha-(1-aminoethyl)-, (S-(R*,S*))-, (1S,2R)-(+)-Phenylpropanolamine, 27818-48-0, NSC-9920, (1S,2R)-PHENYLPROPANOLAMINE, norpseudoephedrine, (R*,S*)-isomer, BDBM50405613, CCG-39586, PDSP1_001348, PDSP2_001332, AKOS027322360, (1S,2R)-(+)-Norephedrine, 98%, AN-5886, DB00397, SDCCGMLS-0066900.P001, Benzenemethanol, (R*,S*)-(.+-.)-, L-.alpha.-(1-Aminoethyl)benzyl alcohol, NCGC00178157-01, NCGC00178157-02, DL-.alpha.-(1-aminoethyl)benzyl alcohol, LS-97285, LS-97462, norpseudoephedrine, (S-(R*,R*))-isomer, (1S,2R)-2-amino-1-phenyl-propan-1-ol, Benzyl alcohol, .alpha.-(1-amino-ethyl), LS-176795, AB00375975, N0631, DL-.alpha.-hydroxy-.beta.-aminopropylbenzene, (1S,2R)-(+)-2-Amino-1-phenyl-1-propanol, C02343, AB00375975_05, I01-8913, BRD-K27853494-001-02-5, BRD-K27853494-003-04-7, UNII-33RU150WUN component DLNKOYKMWOXYQA-VXNVDRBHSA-N, UNII-683H0R9659 component DLNKOYKMWOXYQA-VXNVDRBHSA-N, 753492-51-2

ID: 473

InChIKey: DLNQCQJCIITVHC-UHFFFAOYSA-N
SMILES: CN1CCC2=CC3=C(C=C2C1O)OCO3.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71833
synonyms found at PubChem are:
Hydrastinine Hydrochloride, 4884-68-8, Hydrastinine (hydrochloride), HYDRASTININE HCL, SR-05000001543, Hydrastinine hydrochloride [NF], Prestwick_920, EINECS 225-497-3, Hydrastinine hydrochloirde, CAS-4884-68-8, AC1L2GW1, AC1Q3EV7, DSSTox_CID_27854, DSSTox_RID_82607, C11H13NO3.HCl, DSSTox_GSID_47878, SPECTRUM310006, CHEMBL1517651, DTXSID0047878, CTK4J1006, 6592-85-4 (Parent), HMS1568H11, Pharmakon1600-00310006, HY-B1181, NSC93766, Tox21_200396, 5864AF, CCG-40133, NSC-93766, NSC755892, AKOS030526822, CS-4790, NSC-755892, 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-ol hydrochloride(1:1), NCGC00095862-01, NCGC00257950-01, SR-05000001543-2, 1,5-g]isoquinolin-5-ol, 5,6,7,8-tetrahydro-6-methyl-, hydrochloride, 1,3-Dioxolo[4,5-g]isoquinolin-5-ol, 5, 6,7,8-tetrahydro-6-methyl-, hydrochloride, 6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-ol hydrochloride, ST025365, 6-methyl-5,6,7,8-tetrahydro-2H-1,3-dioxolano[4,5-g]isoquinolin-5-ol, chloride, SCHEMBL1650017, AKOS026750155

ID: 474

InChIKey: DLYVTEULDNMQAR-SRNOMOOLSA-N
SMILES: C[C@H](CCC(=O)OC)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 10960835
synonyms found at PubChem are:
Methyl cholate, Cholic acid, methyl ester, 1448-36-8, CHOLIC ACID METHYL ESTER, UNII-E1P59HQX4Q, E1P59HQX4Q, DLYVTEULDNMQAR-SRNOMOOLSA-N, NSC 126794, C25H42O5, Cholic acid methyl, EINECS 215-903-7, EC 215-903-7, SCHEMBL338241, CHEMBL1078052, MolPort-004-285-584, Methyl 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-ate, ZX-AT021390, 7142AA, BDBM50442869, ZINC49767861, AKOS016009904, OR28947, AS-10489, Cholan-24-oic acid, 3,7,12-trihydroxy-, methyl ester, (3.alpha.,5.beta.,7.alpha.,12.alpha.)-, SC-49728, Methyl 3,7,12-trihydroxycholan-24-oate #, ST24031189, A-7717, J-008013, Methyl 3.alpha.,7.alpha.,12.alpha.-trihydroxy-5.beta.-cholanate, Methyl 3.alpha.,7.alpha.,12.alpha.-trihydroxy-5.beta.-cholanoate, 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oic acid Methyl ester, Methyl 3.alpha.,7.alpha.,12.alpha.-trihydroxy-5.beta.-cholan-24-oate, 120909-93-5, methyl (4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanoate

ID: 475

InChIKey: DMCJLRGWPYVYCQ-MDZDMXLPSA-N
SMILES: C1=CC=C(C(=C1)C(=O)O)OC(=O)/C=C/C(=O)OC2=CC=CC=C2C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 16667734
synonyms found at PubChem are:
BISSALICYL FUMARATE, Bis(salicyl) fumarate, SPECTRUM1505324, CHEMBL1374986, SCHEMBL13351990, CCG-39984, NCGC00095913-01

ID: 476

InChIKey: DMDGGSIALPNSEE-UHFFFAOYSA-N
SMILES: C1NC2=C(C=C(C(=C2)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N1

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3647
synonyms found at PubChem are:
hydroflumethiazide, 135-09-1, Hidroflumetiazid, Diuredemina, Glomerulin, Hydroflumethizide, Diurometon, Flutizide, Hidroalogen, Spandiuril, Robezon, Saluron, Enjit, Trifluoromethylhydrothiazide, Bristurin, Diucardin, Elodrine, Hydrenox, Leodrine, Olmagran, Rodiuran, Vergonil, Bristab, Finuret, Rontyl, Sisuril, Hydol, NaClex, Di-ademil, Dihydroflumethazide, Dihydroflumethiazide, Trifluoromethylhydrazide, Hydroflumethazide, Elodrin, Hidroflumetiazida, Metforylthiadiazin, Hydroflumethiazidum, Metflorylthiazidine, Methforylthiazidine, Rivosil, Idroflumetiazide, Di-adenil, Metforylthiazidin, Naciex (glaxo), Idroflumetiazide [DCIT], component of Salutensin, 6-(Trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, Hidroflumetiazida [INN-Spanish], Hydroflumethiazidum [INN-Latin], NSC 44627, Saluron (TN), UNII-501CFL162R, C8H8F3N3O4S2, HSDB 3340, Hydroflumethiazide [INN:BAN:JAN], 6-Trifluoromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, EINECS 205-173-8, BRN 0342692, 3,4-Dihydro-6-trifluoromethyl-7-sulfamoylbenzo-1,2,4-thiadiazine 1,1-dioxide, 3,4-Dihydro-7-sulfamyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Trifluoromethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 7-Sulfamyl-6-trifluoromethyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide, 6-(Trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, MLS000028516, CHEBI:5784, 501CFL162R, Hydroflumethiazide (JAN/USP/INN), NSC44627, 7-Sulfamyl-6-trifluoromethyl-3,4-dihydro-1,2,4-benzothiadiazine 1, 1-dioxide, 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, NCGC00016401-01, CAS-135-09-1, SMR000058284, DSSTox_CID_3132, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, DSSTox_RID_76886, DSSTox_GSID_23132, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1, 6-Trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 7-Sulfamoyl-6-trifluoromethyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 2H-1,2, 4-Benzothiadiazine-7-sulfonamide, 3, 4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide, 3, 4-Dihydro-6-trifluoromethyl-7-sulfamoylbenzo-1,2,4-thiadiazine 1, 1-dioxide, 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulphonamide-1,1-dioxide, 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulphonamide-1,1-dioxide, 3,4-Dihydro-7-sulfamoyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-(Trifluoromethyl)-3,4-dihydro-2H-benzo-[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide, 6-Trifluoromethyl-3, 4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 6-Trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2, 4-benzothiadiazine-1,1-dioxide, SR-01000003094, River, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1?^{6},2,4-benzothiadiazine-7-sulfonamide, Prestwick_268, 7-Sulfamoyl-6-tri, adiazine 1,1-dioxide, Hydroflumethiazide [USP:INN:BAN:JAN], Spectrum_000905, Opera_ID_326, AC1L1GEH, AC1Q4JYO, Prestwick0_000013, Prestwick1_000013, Prestwick2_000013, Prestwick3_000013, Spectrum2_001010, Spectrum3_000460, Spectrum4_000010, Spectrum5_000832, D00WAM, cid_3647, CHEMBL1763, SCHEMBL27028, 3, 4-Dihydro-6-trifluorom, BSPBio_000045, BSPBio_002140, KBioGR_000359, KBioSS_001385, 4-27-00-08035 (Beilstein Handbook Reference), MLS001148090, DivK1c_000512, SPECTRUM1500341, BMCL182567 Compound 6b, SPBio_001139, SPBio_001966, BPBio1_000051, GTPL7197, DTXSID3023132, BDBM25897, CTK8C4452, HMS501J14, KBio1_000512, KBio2_001385, KBio2_003953, KBio2_006521, KBio3_001360, DMDGGSIALPNSEE-UHFFFAOYSA-N, MolPort-001-771-232, NINDS_000512, 3,2,4-thiadiazine 1,1-dioxide, HMS1568C07, HMS1920F05, HMS2091L13, HMS2095C07, HMS2235E09, HMS3259C15, HMS3371H03, HMS3712C07, Pharmakon1600-01500341, ZINC897225, ZX-AP007542, Tox21_110422, 6273AA, ANW-72013, CCG-40228, NSC-44627, NSC757071, PC0903, 3,2,4-benzothiadiazine 1,1-dioxide, AKOS015913797, Tox21_110422_1, DB00774, MCULE-8204847370, NC00496, NSC-757071, SB01887, VZ25545, IDI1_000512, NCGC00016401-02, NCGC00016401-03, NCGC00016401-04, NCGC00016401-05, NCGC00016401-06, NCGC00016401-09, NCGC00023353-03, NCGC00023353-04, AJ-24271, CC-13172, CPD000058284, KB-82360, LS-40451, SAM002703134, WLN: T66 BSWM EM DHJ HXFFF ISZW, ZB015131, SBI-0051411.P003, AX8006313, DB-042267, TC-160758, AB00052016, FT-0614319, Hydroflumethiazide, analytical standard, ~97%, C07763, D00654, AB00052016_15, A806882, C-20051, 3,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, J-006640, SR-01000003094-2, SR-01000003094-3, SR-01000003094-5, 6-Trifluoromethyl-3,2,4-benzothiadiazine 1,1-dioxide, BRD-K36862742-001-05-8, BRD-K36862742-001-15-7, BRD-K36862742-001-24-9, I14-45008, 3,4-Dihydro-7-sulfamoyl-6-trifluoromethyl-2H-1,2, 4-benzothi, ethyl-2H-1,2, 4-benzothiadiazine-7-sulfonamide 1,1-dioxide, fluoromethyl-3, 4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 6-Trifluoromethyl-7-sulfamoyl-3,2,4-benzothiadiazine-1,1-dioxide, 7-Sulfamoyl-6-trifluoromethyl-3,2,4-benzothiadiazine 1,1-dioxide, Hydroflumethiazide, United States Pharmacopeia (USP) Reference Standard, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1$l;{6},2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-16,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, 2H-1,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide, 3, 4-Dihydro-6-trifluoromethyl-2H-1,2, 4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, 3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7sulphonamide-1,1-dioxide, 3,4-Dihydro-7-sulfamoyl-6-trifluoromethyl-2H-1,2, 4-benzothiadiazine 1,1-dioxide, 6-(Trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide #, 7-Sulfamoyl-6-trifluoromethyl-3, 4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 1,1-bis(oxidanylidene)-6-(trifluoromethyl)-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide, 1,1-DIOXO-6-(TRIFLUOROMETHYL)-1,2,3,4-TETRAHYDRO-1L-6-2-4-BENZATHIADIAZINE-7-SULFONAMIDE, 1,1-Dioxo-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1lambda~6~,2,4-benzothiadiazine-7-sulfonamide

ID: 477

InChIKey: DMJNNHOOLUXYBV-PQTSNVLCSA-N
SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441130
synonyms found at PubChem are:
meropenem, 96036-03-2, Merrem, Meropenemum, Meropenem anhydrous, Antibiotic SM 7338, MERONEM, MEPM, 119478-56-7, Meropen, SM-7338, UNII-YOP6PX0BAO, CHEBI:43968, Meropenem (INN), Meropenem [INN], Meronem (TN), Meropenem Hydrate, YOP6PX0BAO, Merrem I.V. (TN), ICI-194660, SM 7338, (4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, NCGC00016962-01, Merrem (TN), ICI 194660, DSSTox_CID_25526, DSSTox_RID_80930, DSSTox_GSID_45526, (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate, (4r,5s,6s)-3-{[(3s,5s)-5-(Dimethylcarbamoyl)pyrrolidin-3-Yl]sulfanyl}-6-[(1r)-1-Hydroxyethyl]-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]hept-2-Ene-2-Carboxylic Acid, (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID, (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid, CAS-96036-03-2, SR-01000762894, Merrem;Meronem, HSDB 8019, Merrem IV, Meropenem,(S), Neopenem (TN), (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, Meropen (TN), M2279, Mepem (TN), Meropenemum trihydricum, PubChem17275, AC1L9ALL, Prestwick0_001106, Prestwick1_001106, Prestwick2_001106, Prestwick3_001106, CHEMBL127, D0O5FY, Epitope ID:195064, SCHEMBL34442, BSPBio_001212, MLS001401437, BIDD:GT0851, 4-methyl-7-oxo-1-azabicyclo, SPBio_003086, BPBio1_001334, DTXSID7045526, CTK8G0800, DMJNNHOOLUXYBV-PQTSNVLCSA-N, MolPort-006-709-417, HMS1571M14, HMS2051G08, HMS2090C05, HMS2098M14, HMS3715M14, (4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1S)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4R,5S,6S)-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, (4R,5S,6S)-, ZINC3808779, 96036-03-2 (anhydr.), Tox21_110715, Tox21_113794, BDBM50129062, MFCD08600005, AKOS015920140, Tox21_110715_1, CCG-100850, CS-1865, DB00760, KS-5224, NC00100, [3.2.0]hept-2-ene-2-carboxylic acid, NCGC00179259-01, NCGC00253670-01, NCGC00262579-02, AJ-45665, AN-14469, BR-50519, CPD000469184, HY-13678, SAM001246650, SC-18058, SC-45234, SMR000469184, AB0012458, AB1004614, AB2000075, AB00514051, FT-0630992, ST24025110, D08185, J10087, M05727, S-3680, AB00514051-02, AB00698370-05, pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-, 036M032, (4R,5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl), SR-01000762894-3, SR-01000762894-4, (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrol, Meropenem trihydrate, Antibiotic for Culture Media Use Only, (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid, (2S,3R,4R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, (4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4R,5S,6S)-3-[[(3S,5S)-5-(dimethylaminocarbonyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4R,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((S)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, FT-0631096

ID: 478

InChIKey: DMLAVOWQYNRWNQ-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)N=NC2=CC=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 2272
synonyms found at PubChem are:
azobenzene, 103-33-3, Diphenyldiazene, Diazene, diphenyl-, (E)-Diphenyldiazene, Azobisbenzene, Diazobenzene, Azofume, 1,2-Diphenyldiazene, Azodibenzeneazofume, Diphenyldiimide, Azobenzide, Azobenzol, Benzofume, Benzeneazobenzene, Azobenzeen, Azodibenzene, Benzene, azobis-, (E)-1,2-Diphenyldiazene, cis-Azobenzene, Diazene, 1,2-diphenyl-, Benzene, azodi, Azobenzen, trans-Azobenzene, USAF EK-704, (e)-azobenzene, Azobenzeen [Dutch], NCI-C02926, Caswell No. 064, ENT 14,611, Benzene, azodi-, UNII-F0U1H6UG5C, (E)-azobenzol, (E)-azodibenzene, NSC 2102, (Z)-Azobenzene, CCRIS 65, (E)-azobisbenzene, Diazene, diphenyl-, (E)-, HSDB 1513, EINECS 203-102-5, EPA Pesticide Chemical Code 007401, BRN 0742609, F0U1H6UG5C, AI3-14611, CHEBI:58996, CHEBI:190358, DMLAVOWQYNRWNQ-UHFFFAOYSA-N, 1080-16-6, 17082-12-1, DSSTox_CID_123, DSSTox_RID_75385, DSSTox_GSID_20123, diphenyl diimide, CAS-103-33-3, Azobenzene, (E)-, Diazene, diphenyl-, (Z)-, azobis-benzen, (Z)-azobenzol, (Z)-azodibenzene, (Z)-azobisbenzene, Azobenzene, 96%, Azobenzene, 98%, (Z)-diphenyldiazene, 4-(phenylazo)benzene, (E)-diphenyl-diazene, Spectrum_001987, WLN: RNUNR, Spectrum2_001433, Spectrum3_001476, Spectrum4_000448, Spectrum5_001109, ACMC-1C4VK, AC1L1DB6, SCHEMBL32032, BSPBio_003031, KBioGR_000836, KBioSS_002553, 1-16-00-00218 (Beilstein Handbook Reference), KSC177G1F, CHEMBL58835, DivK1c_000502, SCHEMBL565791, SPECTRUM1501172, SPBio_001566, Azobenzene, analytical standard, CHEMBL3184266, DTXSID8020123, CHEBI:58997, CTK0H7312, HMS501J04, KBio1_000502, KBio2_002544, KBio2_005112, KBio2_007680, KBio3_002531, NSC2102, DMLAVOWQYNRWNQ-BUHFOSPRSA-N, MolPort-001-780-130, MolPort-005-943-673, NINDS_000502, BDBM115180, HMS1921N05, HY-B2127, KS-000014FC, NSC-2102, ZINC3871618, Tox21_201458, Tox21_300495, ANW-14890, CCG-39013, LS-362, MFCD00003022, STL283927, ZINC12358663, Azobenzene 10 microg/mL in Isooctane, AKOS015903807, AKOS016042359, ZINC100005624, CS-6935, MCULE-3504085417, NE10253, RTR-000797, IDI1_000502, NCGC00091871-01, NCGC00091871-02, NCGC00091871-03, NCGC00091871-04, NCGC00091871-05, NCGC00091871-06, NCGC00094554-01, NCGC00094554-02, NCGC00094554-03, NCGC00254531-01, NCGC00259009-01, AN-24630, AS-48863, CJ-10996, CJ-13813, KB-47490, TR-000797, A0565, FT-0622525, ST50826964, Azobenzene, PESTANAL(R), analytical standard, EN300-83247, C19334, J-000939, I14-17785, I14-93093

ID: 479

InChIKey: DMRMZQATXPQOTP-XIIVPSJUSA-M
SMILES: C1C2[C@@H](C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957473
synonyms found at PubChem are:
8-Bromo-cAMP sodium, HMS3260F09, Tox21_500184, CCG-221488, LP00184, NCGC00260869-01, EU-0100184, 8-Bromoadenosine-3',5'-cyclophosphate sodium, B 7880

ID: 480

InChIKey: DNAGSRDCXSVFLX-YIONKMFJSA-N
SMILES: C1C[C@@H]2CC(C[C@H](C1)N2CC3=CC=CC=C3)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 14403180
synonyms found at PubChem are:
N-BENZYLTROPAN-4-OL, SCHEMBL910594, SCHEMBL911838, CHEMBL3084486, ZINC5683091, CS-0047169, (1R,3r,5S)-9-Benzyl-9-azabicyclo[3.3.1]nonan-3-ol

ID: 481

InChIKey: DNCAZYRLRMTVSF-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)C(=O)O)(C(=O)O)N

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 1222
synonyms found at PubChem are:
(RS)-MCPG, 146669-29-6, 4-(1-amino-1-carboxyethyl)benzoic acid, CHEMBL299683, alpha-Methyl-4-carboxyphenylglycine, alpha-Amino-4-carboxy-alpha-methylbenzeneacetic acid, (+/-)-alpha-Methyl-4-carboxyphenylglycine, (+/-)-alpha-Methyl-(4-carboxyphenyl)glycine, Benzeneacetic acid, a-amino-4-carboxy-a-methyl-, Benzeneacetic acid, alpha-amino-4-carboxy-alpha-methyl-, C10H11NO4, Benzeneacetic acid, alpha-amino-4-carboxy-alpha-methyl-, (+-)-, (R,S)-MCPG, (+/-)-MCPG, ACMC-20cchr, AC1L1AZT, AC1Q5S1R, Lopac0_000747, SCHEMBL715285, ( inverted question mark)-MCPG, (+-)-MCPG, (+/-)MCPG, CTK4C5052, KS-00001CLO, MolPort-003-958-752, HMS3262E16, BCP18268, Tox21_500747, BDBM50030627, BN0322, MFCD00210205, (RS)-?-Methyl-4-carboxyphenylglycine, AKOS005066801, CCG-204832, CS-5708, LP00747, (y)-alpha-Methyl-4-carboxyphenylglycine, (?)-alpha-Methyl-4-carboxyphenylglycine, alpha-Methyl-2-(4-carboxyphenyl)glycine, NCGC00015676-03, NCGC00015676-04, NCGC00015676-05, NCGC00015676-06, NCGC00024542-02, NCGC00024542-03, NCGC00024542-04, NCGC00261432-01, (r,s)-alpha-methyl-4-carboxyphenylglycine, HY-100371, LS-173280, RT-015311, EU-0100747, ST50825577, Benzeneacetic acid,a-amino-4-carboxy-a-methyl-, M 4796, L000020, SR-01000075733, J-008240, SR-01000075733-1, 4-(1-Amino-1-carboxy-ethyl)-benzoic acid(S-M4CPG), 4-(2-amino-1-hydroxy-1-oxopropan-2-yl)benzoic acid, ( inverted question mark)-alpha-Methyl-4-carboxyphenylglycine

ID: 482

InChIKey: DNFMJYXRIMLMBZ-UHFFFAOYSA-N
SMILES: C1CCN(C1)CC2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)Cl.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 14412
synonyms found at PubChem are:
Reactrol, Allercure hydrochloride, AL 20, EINECS 214-605-4, P 48, 1-p-Chlorobenzyl-pyrrolidyl-methylene-benzimidazole hydrochloride, 1-(p-Chlorobenzil)-2-pirrolidil-metil-benzimidazolo cloridato [Italian], 1-(p-Chlorobenzyl)-2-(1-pyrrolidinylmethyl)benzimidazole hydrochloride, BENZIMIDAZOLE, 1-(p-CHLOROBENZYL)-2-(1-PYRROLIDINYLMETHYL)-, MONOHYDROCHLORIDE, C19H20ClN3.HCl, AC1L23S7, LS-32751, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ium-1-ylmethyl)benzimidazole chloride, AC1LCWD7, AKOS026750222, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole; hydron; chloride, Clemizole hydrochloride, 1163-36-6, Allercur, Clemizole (hydrochloride), Clemizole HCl, UNII-85W6I13D8M, Clemizole hydrochloride [JAN], MLS000120342, 85W6I13D8M, SMR000058430, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole hydrochloride, DSSTox_CID_25136, DSSTox_RID_80695, DSSTox_GSID_45136, Clemizole hydrochloride (JAN), 1-p-Chlorobenzyl-2-(1-pyrrolidinyl)methylbenzimidazole hydrochloride, 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)-benzimidazolmonohydrochloride, 1-[(4-Chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-1H-benzimidazole hydrochloride, SR-01000000057, NCGC00015243-02, CAS-1163-36-6, Clemizole.HCl, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidinylmethyl)benzimidazole, chloride, Allercur (TN), Reactrol (TN), Prestwick_116, allercurehydrochloride, AC1NSGXI, Clemizole(hydrochloride), Opera_ID_1842, MLS000028396, MLS002222168, SCHEMBL210095, DTXSID9045136, CHEBI:31409, AOB4996, EX-A346, DNFMJYXRIMLMBZ-UHFFFAOYSA-N, MolPort-003-940-752, 1-(p-Chlorobenzil)-2-pirrolidil-metil-benzimidazolo cloridato, HMS1568N15, Pharmakon1600-01505990, BCP11344, KS-00001DL1, Tox21_110108, Tox21_500284, HY-30234A, NSC759290, SBB057808, AKOS024370943, Tox21_110108_1, CCG-213997, CS-1489, LP00284, MCULE-2180061700, NSC-759290, NCGC00015243-10, NCGC00093738-01, NCGC00093738-02, NCGC00180972-01, NCGC00260969-01, 1163-36-6 (HCl), AN-48749, BC635891, Clemizole hydrochloride, >=98% (HPLC), KB-151548, C3468, EU-0100284, FT-0607159, ST51007033, C 5040, D01705, W-5052, 163C366, A803600, SR-01000000057-2, SR-01000000057-8, SR-01000000057-10, 1-(p-chlorobenzil)-2-pirrolidil-metil-benzimidazolocloridato, 1-p-chlorobenzyl-pyrrolidyl-methylene-benzimidazolehydrochloride, 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)benzimidazole Hydrochloride, 1-p-chlorobenzyl-2-[1-pyrrolidinyl]-methylbenzimidazole hydrochloride, 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole hydrochloride, 1-[(4-chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)benzimidazole hydrochloride, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole;hydrochloride, 1-[(4-Chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzoimidazole hydrochloride

ID: 483

InChIKey: DNKCFBJMFIUNRS-UHFFFAOYSA-N
SMILES: CC(C)(CC1=CC=CC=C1)NC.CC(C)(CC1=CC=CC=C1)NC.OS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 71611
synonyms found at PubChem are:
Mephentermine sulfate, 1212-72-2, Wyamine sulfate, Fentermin, Mephentermine hemisulfate, Mephentermine hemisulfate salt, Mephentermine Hemisulphate, Mephentermine sulphate, UNII-580655Z8RR, EINECS 214-923-3, N,alpha,alpha-Trimethylphenethylamine sulfate (2:1), 580655Z8RR, DSSTox_CID_27760, DSSTox_RID_82537, DSSTox_GSID_47780, Phenethylamine, N,alpha,alpha-trimethyl-, sulfate (2:1), Benzeneethanamine, N,alpha,alpha-trimethyl-, sulfate (2:1), N,2-dimethyl-1-phenylpropan-2-amine;sulfuric acid, NCGC00016570-01, CAS-1212-72-2, Mephentermine sulfate [USP], N,2-dimethyl-1-phenylpropan-2-amine; sulfuric acid, Prestwick_94, Wyamine sulfate (TN), Mephentermine (sulfate), AC1L2GHF, SCHEMBL121177, CHEBI:6756, 100-92-5 (Parent), CHEMBL3184799, DTXSID1047780, 2C11H17N.H2O4S, HMS1570A14, HMS2097A14, HMS3714A14, Tox21_110501, AKOS030526078, Tox21_110501_1, CCG-220726, NCGC00016570-06, AN-17224, LS-103754, FT-0751658, D01018, N,|A,|A-Trimethylphenethylamine hemisulfate salt, N,2-dimethyl-1-phenylpropan-2-amine hemisulfate, C-55219, SR-01000872629, SR-01000872629-1, N,2-dimethyl-1-phenyl-propan-2-amine; sulfuric acid, Mephentermine Hemisulphate 1.0 mg/ml in Methanol (as free base), AC1LAP3Q, 2-Propanamine, 2,n-dimethyl-1-phenyl-, sulfate, methyl-(2-methyl-1-phenylpropan-2-yl)azanium sulfate

ID: 484

InChIKey: DNTDOBSIBZKFCP-UTONKHPSSA-N
SMILES: CC(C)(C)NC[C@H](COC1=CC=CC2=C1CCCC2=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6420066
synonyms found at PubChem are:
levobunolol hydrochloride, (+) -Levobunolol hydrochloride, 27867-05-6, ent-Levobunolol, Hydrochloride, d-Bunolol Hydrochloride, (+)-Bunolol Hydrochloride, UNII-2L31MJM4SE, 2L31MJM4SE, 27912-14-7, Prestwick_1033, AC1O4WIS, Dextrobunolol hydrochloride, (R-Bunolol Hydrochloride)"", MLS002154036, Bunolol hydrochloride, (+)-, CHEMBL1704116, CTK8F9458, DTXSID90423567, HMS1570L15, 47141-42-4 (acid), AKOS030242219, API0003157, CCG-220857, SMR001233363, FT-0670772, J-016904, ent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride), ent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride), UNII-W0Q9J8634Z component DNTDOBSIBZKFCP-UTONKHPSSA-N, (R)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro- 1(2H)-naphthalenone Hydrochloride, 1(2H)-Naphthalenone, 5-((2R)-3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, hydrochloride (1:1), 5-[(2R)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one hydrochloride, 5-[(2R)-3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone Hydrochloride, 5-{[(2R)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3,4-dihydro-1(2H)-naphthalenone hydrochloride

ID: 485

InChIKey: DNTDOBSIBZKFCP-YDALLXLXSA-N
SMILES: CC(C)(C)NC[C@@H](COC1=CC=CC2=C1CCCC2=O)O.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 441415
synonyms found at PubChem are:
Gotensin, Betagan, Vistagan, Akbeta, Levobunolol HCl, l-Bunolol hydrochloride, UNII-O90S49LDHH, O90S49LDHH, EINECS 248-725-3, W 7000A, (-)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalene-1(2H)-one hydrochloride, 1(2H)-Naphthalenone, 3,4-dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-, hydrochloride, (-)-, 1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, hydrochloride, (-)-, AC1L9B4G, Levobunolol hydrochloride [USAN:USP], tert-butyl-[(2S)-2-hydroxy-3-[(5-oxo-7,8-dihydro-6H-naphthalen-1-yl)oxy]propyl]azanium chloride, levobunolol hydrochloride, Levobunolol (hydrochloride), Levobunolol.HCl, (-) -Levobunolol hydrochloride, 27912-14-7, CHEBI:6439, l-Bunolol, DSSTox_CID_777, (-)-3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2H)-naphthalenone hydrochloride, (-)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone hydrochloride, DSSTox_RID_75784, DSSTox_GSID_20777, 5-({(2S)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl}oxy)-3,4-dihydronaphthalen-1(2H)-one hydrochloride, W-7000A, C17H25NO3.HCl, NCGC00016801-01, CAS-27912-14-7, Levobunolol hydrochloride [USAN], Prestwick_167, Betagan (TN), AC1NR4EJ, Levobunolol, Hydrochloride, levobunolol monohydrochloride, SCHEMBL42262, MLS002154030, CHEMBL1201177, DTXSID6020777, CTK8G0556, DNTDOBSIBZKFCP-YDALLXLXSA-N, MolPort-003-848-379, HMS1570J15, HY-B1035, Tox21_110617, Levobunolol hydrochloride (JAN/USP), AKOS030526127, Tox21_110617_1, CCG-220847, CS-4554, LS-7472, W 6421A, ACM27867056, NCGC00016801-05, AN-15275, SMR001233357, D01025, UNII-W0Q9J8634Z component DNTDOBSIBZKFCP-YDALLXLXSA-N, 5-[(2S)-3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one hydrochloride, 5-[(2S)-3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone, 5-{[3-(tert-butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one hydrochloride, (2S)-N-(tert-butyl)-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium chloride, 1(2H)-Naphthalenone, 3,4-dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-, hydrochloride,(-)-, 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one hydrochloride, 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one hydrochloride, FT-0630538

ID: 486

InChIKey: DNTGGZPQPQTDQF-XBXARRHUSA-N
SMILES: CCN(C1=CC=CC=C1C)C(=O)/C=C/C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 688020
synonyms found at PubChem are:
crotamiton, 483-63-6, N-Ethyl-o-crotonotoluidide, Crotamitone, Eurax, Veteusan, Eurasil, Euraxil, trans-Crotamiton, Crotamitonum, Crotan, Crotonyl-N-ethyl-o-toluidine, Crotalgin, 124236-29-9, Caswell No. 431B, Crotamitonum [INN-Latin], Crotamitex, UNII-2EEH27851Y, o-CROTONOTOLUIDIDE, N-ETHYL-, EINECS 207-596-3, EPA Pesticide Chemical Code 055701, BRN 3275497, N-Ethyl-N-(2-methylphenyl)-2-butenamide, AI3-17732, 2-Butenamide, N-ethyl-N-(2-methylphenyl)-, DNTGGZPQPQTDQF-XBXARRHUSA-N, 2EEH27851Y, (E)-N-Ethyl-N-(o-tolyl)but-2-enamide, N-ethyl-N-(2-methylphenyl)but-2-enamide, (E)-N-ethyl-N-(2-methylphenyl)but-2-enamide, Q-200893, Bestloid, SMR000059145, Crotamiton, (E)-, (2E)-N-ethyl-N-(2-methylphenyl)but-2-enamide, SR-01000759366, N-Crotonyl-N-ethyl-o-toluidine, CHEBI:31439, Crotamiton [INN:BAN:JAN], Crotamiton [USP:INN:BAN:JAN], Eurax (TN), AC1LEL5N, AC1Q2YLR, Prestwick2_000951, Prestwick3_000951, N-Ethyl-o-crotonotoluidine, D0T3NY, G 7857, AC1Q5IA6, N-Ethyl- o-crotonotoluidide, SCHEMBL32934, BSPBio_000942, BSPBio_002722, Crotamiton (JAN/USP/INN), 3-12-00-01856 (Beilstein Handbook Reference), MLS000759489, MLS001424003, MLS002222307, MLS002695895, N-Ethyl-ortho-crotonotoluidide, SPECTRUM1505271, 2-Butenamide, N-ethyl-N-(2-methylphenyl)-, (E)-, 2-Butenamide, N-ethyl-N-(2-methylphenyl)-, (2E)-, BPBio1_001038, component of Eurax (Salt/Mix), CHEMBL1200709, ZINC56427, MolPort-001-794-624, N-Ethyl-o-crotonotoluidide, 97%, HMS1570P04, HMS1922P21, HMS2051E10, HMS2090A10, HMS2093O12, HMS2097P04, HMS2234E16, HMS3714P04, Pharmakon1600-01505271, BCP13315, HY-B1177, NSC78382, CCG-39402, MFCD00026989, NSC-78382, NSC758951, SBB057407, (E)-N-ethyl-N-o-tolylbut-2-enamide, AKOS015892746, CS-4730, N-Ethyl-N-(2-methylphenyl)-butenamide, NC00107, NSC-758951, NCGC00094571-01, NCGC00094571-02, NCGC00094571-03, NCGC00094571-04, NCGC00094571-05, AK307309, AS-11641, BBV-42867418, CC-26001, CPD000059145, LS-55636, SAM001246702, SC-15884, SC-89488, trans-N-Ethyl-N-(o-tolyl)-2-butenamide, ZB001632, SBI-0206763.P001, 2-Butenamide,N-ethyl-N-(2-methylphenyl)-, AB2000238, AB00513973, E0814, N-Ethyl-N-(2-methylphenyl)-2-butenamide #, ST50409628, (E)-N-ethyl-N-(2-methylphenyl)-2-butenamide, D01381, AB00513973-09, AB00513973_10, 483C636, A827519, I04-0177, SR-01000759366-4, SR-01000759366-6, BRD-K13240564-001-01-8, BRD-K57179821-001-05-5, BRD-K57179821-001-08-9, I01-20166, Crotamiton, British Pharmacopoeia (BP) Reference Standard, Crotamiton, European Pharmacopoeia (EP) Reference Standard, UNII-D6S4O4XD0H component DNTGGZPQPQTDQF-XBXARRHUSA-N, Crotamiton, United States Pharmacopeia (USP) Reference Standard, InChI=1/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4

ID: 487

InChIKey: DNTNDFLIKUKKOC-UHFFFAOYSA-N
SMILES: CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 42080
synonyms found at PubChem are:
Gabexato mesilato [Spanish], Ethyl p-(6-guanidinohexanoxyloxy)benzoate methanesulfonate, Ethyl p-(6-guanidinohexanoyloxy) benzoate methanesulfonate, p-Hydroxybenzoic acid ethyl ester 6-guanidinohexanoate mesilate, [N'-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]carbamimidoyl]azanium; methanesulfonate, UNII-E3Q07L0649, Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester, monomethanesulfonate, E3Q07L0649, Gabexato mesilato, Gabexate mesilate [JAN], AC1L272G, CTK8F9977, C16H23N3O4.CH4O3S, MolPort-003-983-435, 39492-01-8 (Parent), AKOS026749879, LS-35906, [N'-[6-(4-ethoxycarbonylphenoxy)-6-oxo-hexyl]carbamimidoyl]ammonium, Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester,monomethanesulfonate, Gabexate mesylate, 56974-61-9, Gabexate mesilate, Gabexate monomethanesulfonate, Gabexate (mesylate), Megacart, Gabexate Methanesulfonate, FOY, NCGC00017121-01, CPD000058918, CAS-56974-61-9, DSSTox_CID_25591, DSSTox_RID_80986, DSSTox_GSID_45591, C17H27N3O7S, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid ethyl ester mesylate, 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxyl]benzoic acid ethyl ester mesylate salt, SMR000058918, SR-01000597763, Arodate, Megacert, Mesyl Gabexate, Arodate (TN), PubChem4068, AC1O7GMA, Gabexate mesilate (JP17), MLS001401400, MLS002222309, MLS006010132, SCHEMBL317799, CHEMBL1398351, DTXSID0045591, CHEBI:31641, FOY-S 983, KS-00000XPD, 56974-61-9 (mesylate), FOY 007, MolPort-006-822-562, HMS1571I17, HMS2051A22, HMS2098I17, HMS2230M20, HMS3268G12, HMS3370J02, HMS3393A22, HMS3655F19, HMS3715I17, BCP13557, HY-B0385, Tox21_110789, AC-467, MFCD00210299, AKOS015889904, AKOS025402087, Tox21_110789_1, API0024746, CCG-100903, CCG-221008, CS-2457, KS-1203, NC00153, VA10991, ACM39492018, NCGC00025297-04, BC208332, SAM001246730, SMR002530330, AB2000505, KB-188547, FT-0630694, G0464, D01672, J10214, 492G018, A831268, C-22025, I06-0358, SR-01000597763-1, SR-01000597763-2, 56974-61-9 39492-01-8(base), ethyl 4-(6-guanidinohexanoyloxy)benzoate methanesulfonate, Gabexate mesylate, analytical standard, for drug analysis, ethyl 4-((6-guanidinohexanoyl)oxy)benzoate methanesulfonate, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate, 4-[6-(diaminomethylideneamino)-1-oxohexoxy]benzoic acid ethyl ester; methanesulfonic acid, ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate; methanesulfonic acid, ethyl 4-[6-[bis(azanyl)methylideneamino]hexanoyloxy]benzoate; methanesulfonic acid, 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic Acid Ethyl Ester Monomethanesulfonate

ID: 488

InChIKey: DNTSIBUQMRRYIU-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 644213
synonyms found at PubChem are:
GW9662, 22978-25-2, 2-Chloro-5-nitro-N-phenylbenzamide, GW 9662, 2-Chloro-5-nitrobenzanilide, GW-9662, MLS001056751, CHEBI:79993, 2-Chloro-5-nitro-N-phenyl-benzamide, IN1303, 2-Chloro-5-nitro-N-4-phenylbenzamide, benzamide, 2-chloro-5-nitro-N-phenyl-, SMR000326735, (2-chloro-5-nitrophenyl)-N-benzamide, SR-01000075999, Tocris-1508, Spectrum5_001989, Lopac-M-6191, D00ACX, D05THB, AC1LD8S0, DSSTox_CID_20723, DSSTox_RID_79570, DSSTox_GSID_40723, Lopac0_000798, BSPBio_001021, KBioGR_000361, KBioSS_000361, SCHEMBL420231, CHEMBL375270, cid_644213, GTPL3442, DTXSID8040723, BCBcMAP01_000086, BDBM55936, CTK6H1023, KBio2_000361, KBio2_002929, KBio2_005497, KBio3_000701, KBio3_000702, ZINC39173, EX-A595, DNTSIBUQMRRYIU-UHFFFAOYSA-N, MolPort-001-526-073, Bio2_000341, Bio2_000821, HMS1362C03, HMS1792C03, HMS1990C03, HMS2235C11, HMS3262O18, HMS3267P20, HMS3372P17, HMS3403C03, HMS3649C18, HMS3651L10, AOB31774, BCP06354, 2-Chloro-5-nitrobenzanilide, 97%, Tox21_301993, Tox21_500798, MFCD01215270, s2915, SBB006523, STL260137, AKOS000155195, Benzamide,2-chloro-5-nitro-N-phenyl-, CCG-204882, CS-1102, DB07863, LP00798, MCULE-8174475490, 2-chloranyl-5-nitro-N-phenyl-benzamide, IDI1_002096, Benzanilide, 2-chloro-5-nitro- (8CI), NCGC00015688-01, NCGC00015688-02, NCGC00015688-03, NCGC00015688-04, NCGC00015688-05, NCGC00015688-06, NCGC00015688-07, NCGC00015688-08, NCGC00015688-09, NCGC00025193-01, NCGC00025193-02, NCGC00025193-03, NCGC00025193-04, NCGC00025193-05, NCGC00025193-06, NCGC00025193-07, NCGC00255683-01, NCGC00261483-01, AS-14069, GW9662, >98% (HPLC), HY-16578, SC-53751, ST055753, AB0109180, CAS-22978-25-2, TX-017635, EU-0100798, FT-0664839, TL80090868, Z6199, Benzamide, 2-chloro-5-nitro-N-phenyl- (9CI), C15627, J90030, M 6191, S-7731, J-014928, SR-01000075999-1, SR-01000075999-3, SR-01000075999-6, SR-01000075999-9, BRD-K93258693-001-02-5, BRD-K93258693-001-05-8, Z27782632

ID: 489

InChIKey: DNVPQKQSNYMLRS-APGDWVJJSA-N
SMILES: C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)O)C)C

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 444679
synonyms found at PubChem are:
ERGOSTEROL, 57-87-4, Provitamin D2, UNII-Z30RAY509F, Ergosterin, Ergosta-5,7,22E-trien-3beta-ol, Z30RAY509F, CHEBI:16933, 5,7,22-Ergostatrien-3beta-ol, 3beta-Hydroxy-5,7,22-ergostatriene, (22E,24S)-24-methylcholesta-5,7,22-trien-3beta-ol, (22E)-ergosta-5,7,22-trien-3beta-ol, Ergosta-5,7,22-trien-3-ol, (3b,22E)-, Ergosta-5,7,22-trien-3beta-ol, (3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, 14-((2E)(1R,4R)-1,4,5-trimethylhex-2-enyl)(1S,5S,2R,11R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-7,9-dien-5-ol, ERG, 24-Methylcholesta-5,7,22-trien-3beta-ol, NSC62791, CCRIS 7220, HSDB 395, Ergosta-5,7,22-trien-3-ol, (3beta,22E)-, (3S,9S,10R,13R,14R,17R)-10,13-dimethyl-17-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol, EINECS 200-352-7, 24alpha-Methyl-22E-dehydrocholesterol, Ergosterol, >=75%, AI3-18876, AC1L9GPL, 24R-Methylcholesta-5,7,2E-trien-3beta-ol, bmse000494, Ergosterol (Provitamin D2), SCHEMBL43194, MEGxm0_000450, CHEMBL1232562, ACon0_000429, ACon1_000637, DNVPQKQSNYMLRS-APGDWVJJSA-N, MolPort-001-740-045, Ergosterol, >=95.0% (HPLC), HY-N0181, ZINC4084618, BDBM50378884, LMST01030093, MFCD00003623, s2297, AKOS015918128, AC-8370, DB04038, DS-4956, NCGC00168889-01, NCGC00168889-02, AJ-47914, Ergosterol hydrate, 96% dry weight 5g, SC-77090, ST073383, KB-296250, CS-0007890, E0018, N2279, ST24046687, (22E)-Ergosta-5,7,22-trien-3.beta.-ol, 7068-EP2275422A1, 7068-EP2305825A1, C01694, Ergosta-5,7,22-trien-3-ol,(3|A,22E)-, 003E623, mixed with Plinia cauliflora ethyl acetate fraction, I14-7742, 45ED0A4C-6FDA-443F-B886-D6C805A76AF2, Ergosterol, 10 mg/mL in chloroform, analytical standard, Ergosterol, European Pharmacopoeia (EP) Reference Standard, Ergosterol, United States Pharmacopeia (USP) Reference Standard, mixed with active tannen enriched fraction of Plinia cauliflora, Ergosterol, Pharmaceutical Secondary Standard; Certified Reference Material, (3S,9S,10R,13R,14R,17R)-17-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 18844-74-1, 37571-51-0

ID: 490

InChIKey: DNXHEGUUPJUMQT-CBZIJGRNSA-N
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5870
synonyms found at PubChem are:
estrone, 53-16-7, folliculin, OESTRONE, Theelin, estrovarin, Estrugenone, follicular hormone, Kestrone, Estron, Follicunodis, Disynformon, Folliculine, Glandubolin, Hiestrone, Hormestrin, Oestroform, Oestronum, Oestroperos, Thelykinin, Femidyn, Folipex, Folisan, Kolpon, Menagen, Oestrin, Unden, Ketohydroxyestrin, Estrone-A, Ketohydroxyoestrin, Endofolliculina, Aquacrine, Crinovaryl, Cristallovar, Crystogen, Destrone, Estrusol, Folikrin, Follestrine, Follestrol, Hormofollin, Hormovarine, Ketodestrin, Menformon, Mestronaq, Ovifollin, Perlatan, Solliculin, Thelestrin, Thynestron, Wynestron, Tokokin, 3-Hydroxyestra-1,3,5(10)-trien-17-one, Ketohydroxy-Estratriene, Estrona, Estrona [Spanish], Femestrone injection, Folliculine benzoate, Ovex (tablets), Estronum [INN-Latin], estrol, 1,3,5(10)-Estratrien-3-ol-17-one, Estrona [INN-Spanish], Estrogenic Substance, Estronum, Fem-O-Gen, Unden (pharmaceutical), 3-Hydroxy-17-keto-estra-1,3,5-triene, Estrone [USAN:INN], Estra-1,3,5(10)-trien-17-one, 3-hydroxy-, E(sub 1), 3-Hydroxyestra-1,3,5(10)-triene-17-one, 3-Hydroxy-oestra-1,3,5(10)-trien-17-one, 1,3,5(10)-Oestratrien-3-ol-17-one, 3-Hydroxy-17-keto-oestra-1,3,5-triene, delta-1,3,5-Estratrien-3beta-ol-17-one, delta-1,3,5-estratrien-3-beta-ol-17-one, delta-1,3,5-Oestratrien-3beta-ol-17-one, delta-1,3,5-oestratrien-3-beta-ol-17-one, Unden (pharmaceutical) (VAN), Fermidyn, Estrin, Oestrone [Steroidal oestrogens], Femestrone inj., Ketophydroxyestrin, Penncap M, WynestronPencap M, 3-Hydroxy-1,3,5(10)-estratrien-17-one, UNII-2DI9HA706A, CCRIS 285, Estrone (TN), (+)-Estrone, Estrone (E1), HSDB 3324, NATURAL ESTROGENIC SUBSTANCE-ESTRONE, 3-hydroxy-estra-1,3,5(10)-trien-17-one, NSC 9699, EINECS 200-164-5, (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one, Estrone (JAN/USP/INN), BRN 1915077, CHEMBL1405, Esterone, MLS000028475, 2DI9HA706A, Menformon A, CHEBI:17263, DNXHEGUUPJUMQT-CBZIJGRNSA-N, CMC_13458, SMR000058338, E0026, DSSTox_CID_2367, E 9750, DSSTox_RID_76560, DSSTox_GSID_22367, (13S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one, [2,4,6,7-3H]-E1, 19973-76-3, hydroxyestrones, Unigen, Wehgen, (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-14-one, (8R,9S,13S,14S)-3-hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one, (+/-)-Oestrone, (+/-)-Estrone, Estrone DL-form [MI], Estrone, (+-)-Isomer, Estrone, (+/-)-, Estrone [USP:INN:BAN], Estrone, (9 beta)-Isomer, Estrone, (8 alpha)-Isomer, Aquest, Oestrone, Estrone, CAS-53-16-7, NCGC00015423-03, Hauck Brand of Estrone, Hyrex Brand of Estrone, Opera_ID_330, Estrone, >=99%, AC1L1LBE, Vortech Brand of Estrone, Prestwick0_000914, Prestwick1_000914, Prestwick2_000914, Prestwick3_000914, Spectrum5_002047, bmse000549, D00ZFP, EC 200-164-5, Lopac0_000513, SCHEMBL21702, BSPBio_000788, 3-08-00-01171 (Beilstein Handbook Reference), MLS001077340, MLS002695951, MLS006011890, BIDD:ER0145, SPBio_002977, BPBio1_000868, GTPL2818, MEGxm0_000444, SGCUT00128, DTXSID4022367, Estrone 1.0 mg/ml in Methanol, ACon0_000083, ACon1_000122, BDBM17289, CTK7J9741, [2,4,6,7-3H]-Estrone, Estra-1,3,5(10)-trien-17-one, 3-hydroxy-, (+/-)-, MolPort-001-742-529, HMS1570H10, HMS2090E22, HMS2097H10, HMS2232O15, HMS3261H07, HMS3714H10, ACT02603, BCP13336, HY-B0234, to_000049, Tox21_113567, Tox21_201375, Tox21_303651, Tox21_500513, AN-195, BBL033470, BL-090, LMST02010004, MFCD00003620, s1665, STK801833, ZINC13509425, AKOS005622512, AKOS007930641, Tox21_113567_1, AC-1395, ACN-032012, CCG-204604, CS-2202, DB00655, DS-6316, EBD2157889, Estrone 100 microg/mL in Acetonitrile, LP00513, SMP1_000123, NCGC00023643-03, NCGC00023643-04, NCGC00023643-05, NCGC00023643-06, NCGC00023643-07, NCGC00023643-08, NCGC00023643-09, NCGC00023643-10, NCGC00023643-11, NCGC00023643-12, NCGC00023643-13, NCGC00023643-15, NCGC00179433-01, NCGC00179433-02, NCGC00179433-03, NCGC00257402-01, NCGC00258926-01, NCGC00261198-01, AJ-63983, BC676705, Estrone, meets USP testing specifications, LS-64884, D1,3,5(10)-Estratrien-3-ol-17-one, AB2000203, 3-Hydroxyestra-1(10),2,4-trien-17-one, 3-hydroxyl-1,3,5(10)-estratien-17-one, 3-Hydroxyoestra-1,3,5(10)-trien-17-one, AB00382990, Estrone, VETRANAL(TM), analytical standard, EU-0100513, ST24046696, 3-hydroxy-estra-1,3,5(10)-triene-17-one, C00468, D00067, X-1332, AB00382990-16, AB00382990-17, AB00382990_18, estra-1(10),2,4-trien-17-one, 3-hydroxy-, 003E620, SR-01000000085, SR-01000075867, Q-201073, SR-01000000085-3, SR-01000075867-1, BRD-K81839095-001-04-6, BRD-K81839095-001-30-1, 86C77018-146D-4603-ACEA-CA0D8C4F1E2C, Estrone, European Pharmacopoeia (EP) Reference Standard, Z1695906713, UNII-X9XKA379T9 component DNXHEGUUPJUMQT-CBZIJGRNSA-N, Estrone, United States Pharmacopeia (USP) Reference Standard, Estrone, Pharmaceutical Secondary Standard; Certified Reference Material, Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-2,4,6-trien-14-one, (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-2,4,6-trien-14-one, 37242-41-4

ID: 491

InChIKey: DNXWUWRYEBKICC-GQCTYLIASA-N
SMILES: CCCC1=C(C(=O)C=CO1)/C=C/O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5955283
synonyms found at PubChem are:
2-PROPYL-3-HYDROXYETHYLENEPYRAN-4-ONE, AC1NZAD5, Spectrum5_000416, BSPBio_003234, CHEMBL3039146, SCHEMBL12998432, CCG-38764, NCGC00178195-01, 3-[(E)-2-hydroxyethenyl]-2-propylpyran-4-one

ID: 492

InChIKey: DOBMPNYZJYQDGZ-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C(=C(C(=O)O2)CC3=C(C4=CC=CC=C4OC3=O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 54676038
synonyms found at PubChem are:
dicumarol, dicoumarol, Bishydroxycoumarin, 66-76-2, dicoumarin, melitoxin, bis-hydroxycoumarin, Antitrombosin, Baracoumin, Dicoumal, Dicumarine, Acadyl, Acavyl, Dicuman, Trombosan, Dicumol, Dufalone, Kumoran, Temparin, Cumid, Cuma, Dicumaol R, Anathrombase, Dicoumarolum, Apekumarol, Dicoumerol, Dicumarinum, Dicumarolum, Bis-3,3'-(4-hydroxycoumarinyl)methane, Bis(4-hydroxycoumarin-3-yl)methane, Di-(4-hydroxy-3-coumarinyl)methane, 3,3'-Methylenebis(4-hydroxycoumarin), Dicumarolo [DCIT], Dwukumarol [Polish], Dicumarolo, Dikumarol, Dwukumarol, Di-4-hydroxy-3,3'-methylenedicoumarin, Dicumarol [INN-Spanish], Dicoumarolum [INN-Latin], 3,3'-Methylen-bis(4-hydroxy-cumarin), Dicumarol [USAN], 3,3'-Methylene-bis(4-hydroxycoumarine), 3,3'-methylenebis(4-hydroxy-2H-chromen-2-one), NC 034, 3,3'-Metilen-bis(4-idrossi-cumarina), 3,3'-Methylenebis(4-hydroxy-1,2-benzopyrone), 3,3'-Methyleen-bis(4-hydroxy-cumarine), 3,3'-methanediylbis(4-hydroxy-2H-chromen-2-one), UNII-7QID3E7BG7, 3,3'-Methylenebis(4-hydroxy-2H-1-benzopyran-2-one), Dicumarol (TN), NSC 17860, 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-, Dicoumarol (INN), 3,3'-Methylenebis[4-hydroxycoumarin], Dicumarol (USAN), NSC 221570, 3,3'-Methylene-bis(4-hydroxycoumarin), CCRIS 3713, Bis-3,3'-(4-oxycoumarinyl)ethylacetate, Coumarin, 3,3'-methylenebis(4-hydroxy-, HSDB 3223, 4,4'-Dihydroxy-3,3'-methylene bis coumarin, C19H12O6, EINECS 200-632-9, NSC 41834, 3,3'-Methylen-bis(4-hydroxy-cumarin) [German], 3,3'-methylenebis(2-hydroxy-4h-chromen-4-one), 3,3'-Methyleen-bis(4-hydroxy-cumarine) [Dutch], 3,3'-Methylene-bis(4-hydroxycoumarine) [French], 3,3'-Metilen-bis(4-idrossi-cumarina) [Italian], BRN 0335444, 7QID3E7BG7, CHEMBL1466, 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one, AI3-14546, CHEBI:4513, symmetric dicoumarol analogue, 1, uncoupler of oxidative respiration, DOBMPNYZJYQDGZ-UHFFFAOYSA-N, Dicoumarol [INN], NSC17860, NSC41834, 3,2-benzopyrone], 2H-1-Benzopyran-2-one), 3,3'-methylenebis(4-hydroxy-, CAS-66-76-2, NCGC00016296-01, 3,3′-Methylenebis(4-hydroxycoumarin), M0216, DSSTox_CID_1729, 3,3'-Methylenebis[4-hydroxy-1,2-benzopyrone], DSSTox_RID_76296, DSSTox_GSID_21729, CHEMBL43154, 3,3'-Methylenebis[4-hydroxy-2H-1-benzopyran-2-one], 2H-1-Benzopyran-2-one, 3,3'-methylenebis(4-hydroxy-, 2-hydroxy-3-[(2-hydroxy-4-oxochromen-3-yl)methyl]chromen-4-one, Coumarin,3'-methylenebis[4-hydroxy-, 3,3'-Methylene-bis[4-hydroxycoumarin], NSC221570, WLN: T66 BOVJ EQ D1- DT66 BOVJ EQ, SR-05000001605, Dicumarol [USAN:USP], 2H-1-Benzopyran-2-one,3'-methylenebis[4-hydroxy-, 2H-1-Benzopyran-2-one],3'-methylenebis[4-hydroxy-, 4-hydroxy-3-[(4-hydroxy-2-oxochromen-3-yl)methyl]chromen-2-one, 4-hydroxy-3-((4-hydroxy-2-oxo-2H-chromen-3-yl)methyl)-2H-chromen-2-one, Prestwick_90, 3,3&prime, Spectrum_000165, Prestwick0_000785, Prestwick1_000785, Prestwick2_000785, Prestwick3_000785, Spectrum2_000144, Spectrum3_000387, Spectrum4_000508, Spectrum5_000871, ChemDiv2_003436, D02TJS, AC1L19PT, Oprea1_150990, SCHEMBL33891, SCHEMBL33892, BSPBio_000890, BSPBio_002173, CBDivE_003005, KBioGR_001055, KBioSS_000645, 5-19-06-00682 (Beilstein Handbook Reference), DivK1c_000896, SPECTRUM1500239, SPBio_000248, SPBio_002829, AC1Q699Q, BPBio1_000980, GTPL6808, 2H-1-Benzopyran-2-one, 3,3'-methylenebis(4-hydroxy)-, DTXSID8021729, BDBM35525, CTK5C5178, HMS502M18, KBio1_000896, KBio2_000645, KBio2_003213, KBio2_005781, KBio3_001393, MolPort-000-422-589, NINDS_000896, HMS1378M04, HMS1570M12, HMS1920E20, HMS2091M10, HMS2097M12, HMS3652P10, HMS3714M12, Pharmakon1600-01500239, HY-N0645, ZINC3869855, Tox21_110357, BBL008904, CCG-34550, MFCD00006857, NSC-17860, NSC756733, s4299, STK801287, 3,3-Methylene-bis[4-hydroxycoumarin], AKOS000520650, Tox21_110357_1, CS-7962, DB00266, MCULE-8095183287, NSC-756733, VZ31493, 3,3 -Methylene-bis[4-hydroxycoumarin], IDI1_000896, NCGC00016296-02, NCGC00016296-03, NCGC00016296-04, NCGC00016296-05, NCGC00016296-07, NCGC00094650-01, NCGC00094650-02, AS-19619, LS-55258, SBI-0051343.P003, FT-0624734, H2893, Y1603, 3,3''''''''-methylenebis[4-hydroxycoumarin, 3,3'-Methylene-bis(4-hydroxycoumarin), 99%, C00796, Coumarin, 3,3'-methylenebis[4-hydroxy-(8CI), D03798, 3,3''''''''-methylenebis(4-hydroxy-coumarin, 3,3''''''''-methylenebis(4-hydroxycoumarin), AB00051966_05, Coumarin, 3,3'-methylenebis[4-hydroxy- (8CI), SR-05000001605-1, SR-05000001605-3, SR-05000001605-4, W-203471, 2H-1-Benzopyran-2-one,3,3'-methylenebis[4-hydroxy-, BRD-K82236179-001-05-0, BRD-K82236179-001-06-8, I14-52299, Z57170530, 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy- (9CI), 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-(9CI), Dicumarol, United States Pharmacopeia (USP) Reference Standard, 4-hydroxy-3-[(4-hydroxy-2-oxo-chromen-3-yl)methyl]chromen-2-one

ID: 493

InChIKey: DOBOYMKCRRLTRF-UHFFFAOYSA-N
SMILES: C1=C(NC=N1)CCSC(=N)N.Br.Br

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 11957573
synonyms found at PubChem are:
Imetit dihydrobromide, 32385-58-3, imetit hydrobromide, CHEBI:64151, S-[2-(Imidazol-4-yl)ethyl]isothiourea, S-{2-[1H-imidazol-4-yl]ethyl}isothiourea dihydrobromide, 2-(1H-imidazol-4-yl)ethyl carbamimidothioate dihydrobromide, W-202327, S-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide, SR-01000075275, EU-0100645, SCHEMBL7974417, CHEMBL1490875, DTXSID7042560, CTK8G0278, DOBOYMKCRRLTRF-UHFFFAOYSA-N, MolPort-003-941-773, Tox21_500645, BN0270, MFCD00153816, AKOS024458620, BCP9000778, CCG-221949, LP00645, ACM32385583, Imetit dihydrobromide, >=98% (HPLC), NCGC00094012-01, NCGC00261330-01, AN-16959, B6424, I-135, S-[2-(Imidazol-4-yl)ethyl]isothiourea 2HBr, SR-01000075275-1, SR-01000075275-3, S-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrochloride, 2-[2-(1H-imidazol-5-yl)ethyl]isothiourea dihydrobromide, [2-(1H-imidazol-4-yl)ethyl]sulfanylmethanimidamide dihydrobromide

ID: 494

InChIKey: DOIRQSBPFJWKBE-UHFFFAOYSA-N
SMILES: CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3026
synonyms found at PubChem are:
dibutyl phthalate, Di-n-butyl phthalate, 84-74-2, n-Butyl phthalate, Butyl phthalate, Celluflex DPB, Elaol, Genoplast B, Palatinol C, Polycizer DBP, Unimoll DB, Dibutyl-o-phthalate, Staflex DBP, Hexaplas M/B, Witcizer 300, Dibutyl 1,2-benzenedicarboxylate, Ergoplast FDB, DIBUTYLPHTHALATE, Kodaflex DBP, DBP (ester), N-Butylphthalate, Phthalic acid dibutyl ester, Ersoplast FDA, Phthalate, di-n-butyl, Uniflex DBP, Hatcol DBP, dibutyl benzene-1,2-dicarboxylate, Dibutyl o-phthalate, RC Plasticizer DBP, 1,2-Benzenedicarboxylic acid, dibutyl ester, Benzene-o-dicarboxylic acid di-n-butyl ester, Phthalic acid, dibutyl ester, o-Benzenedicarboxylic acid, dibutyl ester, RCRA waste number U069, Phthalate, dibutyl-, Caswell No. 292, PX 104, ortho-Dibutyl phthalate, Phthalic acid di-n-butyl ester, Di-n-butylorthophthalate, nutyl phthalate, Dibutyl-1,2-benzenedicarboxylate, Dibutylphthatlate, dibutyl-phthalate, Palatinol DBP, Dibutyl phthalated, NSC 6370, di-n-butyl phthalate (DBuP), UNII-2286E5R2KE, Morflex 240, Uniplex 150, CCRIS 2676, HSDB 922, Di-n-butylester kyseliny ftalove, CHEBI:34687, RAPIDCELLtrade markP, EINECS 201-557-4, 1,2-Benzenedicarboxylic acid, 1,2-dibutyl ester, RCRA waste no. U069, EPA Pesticide Chemical Code 028001, BRN 1914064, o-Benzenedicarboxylic acid dibutyl ester, Di-n-butylester kyseliny ftalove [Czech], 1,2-Benzenedicarboxylic acid dibutyl ester, CHEMBL272485, AI-3-00283, Benzene-o-dicarboxylic acid, di-n-butyl ester, DOIRQSBPFJWKBE-UHFFFAOYSA-N, 2286E5R2KE, Benzenedicarboxylic acid dibutyl ester, Benzenedicarboxylic acid, dibutyl ester, 1,2-dibutyl benzene-1,2-dicarboxylate, DSSTox_CID_1781, Dibutyl ester of 1,2-benzenedicarboxylic acid, DSSTox_RID_76324, DSSTox_GSID_21781, butyl 2-(butoxycarbonyl)benzoate, Phthalate, Butyl, CAS-84-74-2, Phthalate, Dibutyl, Di n Butyl Phthalate, Dibutyl phthalate [NF], SR-05000001549, Bufa, phthalate dibutyl, Dibutyll phthalate, Spectrum_001975, SpecPlus_000628, Dibutyl phthalate, 99%, Spectrum3_000874, Spectrum4_000714, Spectrum5_002068, ACMC-209pw7, D07FLG, Epitope ID:138714, EC 201-557-4, WLN: 4OVR BVO2, Dibutyl phthalate, >=99%, SCHEMBL24051, BSPBio_002547, KBioGR_001267, KBioSS_002541, SPECTRUM330086, KSC119E6H, MLS002177802, BIDD:ER0641, DivK1c_006724, Phthalic acid, bis-butyl ester, AC1L1F08, AC1Q66W8, GTPL6295, DTXSID2021781, CTK0B9263, KBio1_001668, KBio2_002532, KBio2_005100, KBio2_007668, KBio3_002047, NSC6370, Dibutyl phthalate, AR, >=99%, Dibutyl phthalate, LR, >=98%, MolPort-003-665-474, Di-n-butyl phthalate, 99% 5g, Dibutyl 1, 2-benzenedicarboxylate, HMS2091E09, HMS3041E18, Pharmakon1600-00330086, BCP24796, NSC-6370, ZINC1693431, Dibutyl phthalate, Selectophore(TM), Tox21_201729, Tox21_300980, ANW-37829, BBL011532, BDBM50371946, MFCD00009441, NSC755894, SBB060337, STL146650, AKOS005720807, CCG-230933, LS-1840, MCULE-8727957434, NSC-755894, RL05206, RTR-031465, NCGC00090769-01, NCGC00090769-02, NCGC00090769-03, NCGC00090769-04, NCGC00090769-05, NCGC00090769-06, NCGC00090769-07, NCGC00090769-08, NCGC00090769-09, NCGC00254882-01, NCGC00259278-01, AN-24078, CJ-28339, KB-49737, SC-74684, SMR000777923, SBI-0052568.P002, TR-031465, CS-0013564, Dibutyl phthalate, ReagentPlus(R), >=99%, FT-0624680, P0292, ST50406580, C14214, 1,2-Benzenedicarboxylicacid, 1,2-dibutyl ester, Dibutyl phthalate, SAJ special grade, >=98.0%, J-503795, SR-05000001549-1, SR-05000001549-3, BRD-K73477617-001-01-0, BRD-K73477617-001-04-4, Dibutyl phthalate, PESTANAL(R), analytical standard, I14-14981, F0001-2134, Z277540112, Dibutyl phthalate, certified reference material, TraceCERT(R), Dibutyl phthalate, European Pharmacopoeia (EP) Reference Standard, DIBUTYL PHTHALATE (SEE ALSO PEROXISOME PROJECT (DIBUTYL PHTHALATE)), Dibutyl phthalate, United States Pharmacopeia (USP) Reference Standard, PEROXISOME PROJECT (DIBUTYL PHTHALATE) (SEE ALSO DIBUTYL PHTHALATE), 1,2-benzenedicarboxylic acid dibutyl ester; benzenedicarboxylic acid dibutyl ester, Dibutyl Phthalate, Pharmaceutical Secondary Standard; Certified Reference Material, Oy paragraph sign inverted exclamation mark>>uAU+/-(1/2) paragraph signthorn(1/4)xEao yen, 137077-55-5, AU+/-(1/2) paragraph signthorn(1/4)xEa paragraph signthorn paragraph sign inverted exclamation mark>>uo yen, DB7

ID: 495

InChIKey: DOQPXTMNIUCOSY-UHFFFAOYSA-N
SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 62969
synonyms found at PubChem are:
Verapamil hydrochloride, 152-11-4, Verapamil HCl, Manidon, Calcan hydrochloride, Cordilox, Cardibeltin, Cardiabeltin, Cardioprotect, Veroptinstada, Calaptin, Caveril, Civicor, Coraver, Corpamil, Durasoptin, Harteze, Hexasoptin, Hormitol, Ikapress, Inselon, Isoptino, Jenapamil, Lodixal, Magotiron, Praecicor, Robatelan, Vasomil, Vasopten, Verabeta, Veracor, Verahexal, Veraloc, Veramil, Verapin, Verasal, Verasifar, Veratensin, Verdilac, Vetrimil, Elthon, Flamon, Ikacor, Univex, Vortac, Anpec, Ormil, Rapam, Verapamil Ebewe, Verapamil Riker, Verapamil Verla, Civicor Retard, Isoptin Retard, Manidon Retard, Vera-Sanorania, Verapamil Acis, Verapamil Atid, Verapamil Basics, Verapamil Nordic, Verapamil-AbZ, Novapamyl LP, Verapamil NM, Verapamil PB, Verapamil SR, Cordilox SR, Dilacoran HTA, Veracaps SR, Verapamil MSD, Hexasoptin Retard, Verapamil Henning, Arpamyl LP, Verelan SR, Verapamil Injection, (+/-)-VERAPAMIL HYDROCHLORIDE, Berkatens, Cardiagutt, Dignover, Geangin, Izoptin, Lekoptin, Veramex, Verpamil, Akilen, Quasar, Univer, Verapamil chloridrate, Verapamil NM Pharma, Calaptin 240 SR, Novo-Veramil, Verapress 240 SR, D-365 hydrochloride, Verapamil AL, Verapamyl hydrochloride, Apo-Verap, Isoptin SR, Nu-Verap, Covera-HS, Calan SR, 23313-68-0, Iproveratril hydrochloride, Verapamil (hydrochloride), HSDB 3928, (+/-)-Verapamil, Hydrochloride, EINECS 205-800-5, NSC 272366, LU 20175, MLS000069485, NSC 135784, IN1425, NSC657799, Verapamil Hydrochloride (Isoptin, Iproveratril, Calan), SMR000059109, Verelan (TN), Covera-hs (TN), Calan (TN), 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride, 5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride, Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride, Q-201923, (+-)-5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride, 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile hydrochloride, 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]methylamino}-2-(methy lethyl)pentanenitrile, chloride, Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride, (+-)-, Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride, NSC272366, SR-01000000050, 38176-10-2, (S)-(-)-Verapamil Hydrochloride, Covera, Verapamil, HCl, 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride, Prestwick_440, Vasolan (TN), Verapamil hydrochloride [USAN:JAN], Isotopin hydrochloride, Verapamil hydrochloride [USAN:USP:JAN], Opera_ID_1210, ()-Verapamil hydrochlorid, CAS-152-11-4, (y)-Verapamil hydrochloride, AC1L1Y4V, AC1Q3CE8, (?)-Verapamil hydrochloride, CHEMBL1280, DSSTox_CID_14095, DSSTox_RID_79114, Verapamil Hydrochloride,(S), DSSTox_GSID_34095, SCHEMBL33296, C27H39ClN2O4, MLS001055442, MLS002222213, (+-)-Verapamil hydrochloride, (??)-Verapamil hydrochloride, ARONIS24174, C27H38N2O4.HCl, SPECTRUM2300307, DTXSID2034095, BBC/320, BIV1326, DOQPXTMNIUCOSY-UHFFFAOYSA-N, MolPort-002-915-466, ZX-AFC000544, HMS1568M04, HMS1922J16, Pharmakon1600-02300307, BCP06465, HY-A0064, ZX-AS004533, Tox21_201180, Tox21_501237, BG0353, CCG-39491, MFCD00055208, NSC759589, s4202, Verapamil hydrochloride (JP17/USP), AKOS005267117, AC-8483, AN-7969, API0024301, CS-1685, LP01237, NSC-272366, NSC-657799, NSC-759589, NCGC00024710-03, NCGC00094479-01, NCGC00094479-02, NCGC00094479-03, NCGC00094479-04, NCGC00094479-05, NCGC00258732-01, NCGC00261922-01, AC-16228, AS-16018, BC210130, CC-35585, R853, SC-18887, ST066908, AB0018370, LS-161199, EU-0101237, FT-0603360, FT-0655647, ST24050346, 36622-29-4, D00619, EN300-124002, K-4825, V 4629, ( inverted question mark)-Verapamil hydrochloride, 54236-EP2305219A1, 54236-EP2308562A2, 152V114, A816666, I06-0615, SR-01000000050-2, SR-01000000050-4, SR-01000000050-11, Z2210978706, (+/-)-Verapamil hydrochloride, >=99% (titration), powder, Verapamil Hydrochloride 1.0 mg/ml in Methanol (as free base), Verapamil hydrochloride, European Pharmacopoeia (EP) Reference Standard, Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard, (+/-)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-isopropyl-pentanenitrile hydrochloride, 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile hydrochloride, 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride, 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride, 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxy phenyl)-2-isopropylvaleronitrile hydrochloride, 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride, Benzeneacetonitrile,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, monohydrochloride, Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-,monohydrochloride, AC1LCWGV, AKOS015896254, I06-2129, 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile; hydron; chloride, EINECS 245-579-2, SBB057397, AKOS000280876, AKOS025116941, MCULE-4314350683, (1)-(3-Cyano-3-(3,4-dimethoxyphenyl)hex-6-yl)(5,6-dimethoxyphenethyl)methylammonium chloride

ID: 496

InChIKey: DORDKDUSCNWFPJ-BDPMCISCSA-N
SMILES: CC(C)C1=C(C=CC2=C1CCC3[C@@]2(CCCC3(C)C)C)OC

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6708604
synonyms found at PubChem are:
KBio1_001247, SpecPlus_000207, AC1O8FFF, cis-Totarol, methyl ether, TOTAROL METHYL ETHER, DivK1c_006303, DORDKDUSCNWFPJ-BDPMCISCSA-N, (4aS)-7-methoxy-1,1,4a-trimethyl-8-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene

ID: 497

InChIKey: DOUMFZQKYFQNTF-WUTVXBCWSA-N
SMILES: C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 5281792
synonyms found at PubChem are:
rosmarinic acid, 20283-92-5, Rosemary acid, (R)-rosmarinic acid, UNII-MQE6XG29YI, Rosmarinate, MQE6XG29YI, CHEMBL324842, CHEBI:50371, Labiatenic acid, C18H16O8, (R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester, (2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]propanoic acid, 537-15-5, Rosemaric acid, (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-propanoic acid, (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxypropanoic acid, trans-Rosmarinic acid, Benzenepropanoic acid, alpha-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-, Meiji Red Perilla Polyphenol, Rosmarinicacid, Rosmarimic acid, Rosmarinic-acid, CCRIS 9361, RM 21A, 3,4-Dihydroxycinnamic acid 2-ester with 3-(3,4-dihydroxyphenyl)lactic acid, HSDB 7688, NPLC 0542, Rosmarinic acid, 2, Rosmarinic acid, 96%, AC1NQZ3E, bmse000648, D05PTT, AC1Q5R3O, MLS000697677, MEGxp0_000163, SCHEMBL1650675, SCHEMBL2028694, ACon1_001068, CHEBI:92370, cid_5281792, 3-(3,4-DIHYDROXYPHENYL)ACRYLIC ACID-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHYL ESTER, CINNAMIC ACID, 3,4-DIHYDROXY-, 2-ESTER with 3-(3,4-DIHYDROXYPHENYL)LACTIC ACID, DOUMFZQKYFQNTF-WUTVXBCWSA-N, MolPort-001-740-341, HMS2227A13, HMS3266D13, HMS3649C22, ZINC899870, Benzenepropanoic acid, alpha-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-, (R-(E))-, HY-N0529, BDBM50133496, MFCD00017740, AKOS015892734, CCG-207919, CCG-208268, MCULE-4098643324, NCGC00169708-01, AN-14557, AS-35341, SC-44350, SMR000445579, LS-175479, N1768, W1784, C01850, 225R532, SR-01000946599, I14-7740, Q-100246, SR-01000946599-1, (2R)-O-caffeoyl-3-(3,4-dihydroxyphenyl)lactic acid, F0001-0715, 93B6A3BF-927D-4C59-8A49-29BDBC87C194, Rosmarinic acid, primary pharmaceutical reference standard, Rosmarinic acid, European Pharmacopoeia (EP) Reference Standard, Rosmarinic acid, >=98% (HPLC), from Rosemarinus officinalis L., Rosmarinic acid, United States Pharmacopeia (USP) Reference Standard, (2r)-3-(3,4-dihydroxyphenyl)-2-{[3-(3,4-dihydroxyphenyl)acryloyl]oxy}propanoic acid, (R)-2-[3-(3,4-Dihydroxyphenyl)acryloyloxy]-3-(3,4-dihydroxyphenyl)propionic acid, (R,E)-3-(3,4-dihydroxyphenyl)-2-((3-(3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid, (R,E)-3-(3,4-dihydroxyphenyl)-2-(3-(3,4-dihydroxyphenyl)acryloyloxy)propanoic acid, 3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, alpha-(((3,4-Dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxybenzenepropanoic acid, [R-(+)]-?-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid, Benzenepropanoic acid, .alpha.-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-, (R-(E))-, Benzenepropanoic acid, .alpha.-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, (.alpha.R)-

ID: 498

InChIKey: DPJRMOMPQZCRJU-UHFFFAOYSA-M
SMILES: CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 6202
synonyms found at PubChem are:
THIAMINE HYDROCHLORIDE, 67-03-8, Aneurine hydrochloride, Thiamine HCL, Vitamin B1 hydrochloride, Thiamine dichloride, Thiamine chloride hydrochloride, Trophite, Thiamin chloride, vitamin B1, Thiaminium chloride, Beatine, Begiolan, Benerva, Bethiazine, Bevitex, Bevitine, Bithiamin, Bivatin, Clotiamina, Eskapen, Eskaphen, Metabolin, Slowten, Thiaminal, Thiamol, Thiavit, Tiamidon, Tiaminal, Vinothiam, Bedome, Beuion, Bivita, Berin, Biuno, Hybee, Apate drops, Betabion hydrochloride, Lixa-beta, Usaf cb-20, Thiamine chloride, Vetalin S, Vitamin B hydrochloride, Thiaminium chloride hydrochloride, Thiamin hydrochloride, thiamine, Vitaneurin, Thiamine monohydrochloride, Thiamine,hydrochloride, Vitamin b(sub 1) hydrochloride, UNII-M572600E5P, thiamine(2+) dichloride, CHEBI:49105, FEMA No. 3322, CCRIS 1906, M572600E5P, CAS-67-03-8, NCGC00017013-01, EINECS 200-641-8, NSC 36226, 3-((4-amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride, AI3-18993, Thiamine HCl (Vitamin B1), THD, Thiamine Hydrochloride (Vitamin B1), THIAZOLIUM,3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-5-(2-HYDROXYETHYL)-4-METHYL-, 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl}ethan- 1-ol, chloride, chloride, SMR000875246, Thiaminehydrochloride, NSC36226, Thiaminum hydrochloricum, Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride, monohydrochloride, vitamin Bl, Aneurine HCl, Thiamine hydrochloride [USP:JAN], Vitamin b(sup1), 108631-50-1, 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride, Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1), hydrochloride (1:1), Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl- chloride (1:1), hydrochloride (1:1), Prestwick_441, Thiamio hydrochloridum, Thiamine HCL (TN), Thiamine, hydrochloride, I notEuEOB1 NIEaNI, Thiazolium, hydrochloride, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride, Ao degrees .EO NIEaNI, Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride, C12H17ClN4OS.HCl, D02LDV, AC1L1M0I, DSSTox_CID_20622, DSSTox_RID_79516, Thiazolium, monohydrochloride, DSSTox_GSID_40622, SCHEMBL41101, MLS001332447, MLS001332448, Thiamine hydrochloride (USP), AC1Q1S14, CHEMBL1200941, DTXSID0040622, DPJRMOMPQZCRJU-UHFFFAOYSA-M, MolPort-001-798-473, HMS1569P04, Thiamine, monohydrochloride (8CI), BCP27971, HY-N0680, Tox21_110736, MFCD00012780, NSC-36226, s3211, SBB001377, Thiamine hydrochloride, p.a., 98%, AKOS015905506, CCG-220677, CS-8164, MCULE-4868090831, KS-00000W98, Thiamine chloride hydrochloride (JP17), NCGC00017013-02, AS-14151, K101, KB-81106, SC-18327, ST007553, AB0014031, Thiamine hydrochloride, >=98%, FCC, FG, FT-0631293, D02094, Aneurine hydrochloride, Vitamin B1 hydrochloride, Thiamine Hydrochloride (B1), analytical standard, Q-201928, Thiamine hydrochloride, tested according to Ph.Eur., Thiamine hydrochloride, reagent grade, >=99% (HPLC), Thiamine hydrochloride, SAJ special grade, >=98.5%, F0001-2415, F2173-0852, Thiamine hydrochloride, meets USP testing specifications, WLN: T6N CNJ B1 DZ E1- AT5K CSJ D2Q E1 &Q &G &GH, Thiamine Hydrochloride (Vitamin B1) 1.0 mg/ml in Methanol (as free base), Thiamine hydrochloride, European Pharmacopoeia (EP) Reference Standard, Thiamine hydrochloride, United States Pharmacopeia (USP) Reference Standard, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-chloridethiazolium, Thiamine for system suitability, European Pharmacopoeia (EP) Reference Standard, Thiamine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material, 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride hydrochloride, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium hydrochloride chloride, 3-[(4-azaniumyl-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium dichloride, 63-66-1, 70732-86-4, Thiamine HCl (Vitamin B1) solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Thiamine hydrochloride, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, Thiamine hydrochloride, PharmaGrade, EP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, THIAMINE HYDROCHLORIDE; 67-03-8; Aneurine hydrochloride; Thiamine HCL; Vitamin B1 hydrochloride; Thiamine dichloride, AC1LAODT, [5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride, AKOS015896335, I06-2065

ID: 499

InChIKey: DPNGWXJMIILTBS-UHFFFAOYSA-N
SMILES: C1CC(=NC1)C2=CN=CC=C2

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 442649
synonyms found at PubChem are:
Myosmine, 532-12-7, 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine, 3-(1-Pyrrolin-2-yl)pyridine, Miosmine, UNII-9O0A545W4L, 3-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine, 2-(3-Pyridyl)-1-pyrroline, CHEBI:7051, CHEMBL423429, 3-(2-Pyrrolin-2-yl)pyridine, DPNGWXJMIILTBS-UHFFFAOYSA-N, Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-, 9O0A545W4L, Pyridine, 3-(1-pyrrolin-2-yl)-, 3-(1-PYRROLIN-2-YL)-PYRIDINE, CCRIS 9356, Prestwick_202, Spectrum_001130, SpecPlus_000615, Prestwick0_000647, Prestwick1_000647, Prestwick2_000647, Prestwick3_000647, AC1L9D5K, BSPBio_000653, KBioSS_001610, Myosmine, 98% 100mg, 5-23-06-00466 (Beilstein Handbook Reference), DivK1c_006711, SPBio_002574, BPBio1_000719, SCHEMBL5319476, KBio1_001655, KBio2_001610, KBio2_004178, KBio2_006746, MolPort-001-763-158, US8609708, 79 Myosmine, HMS1570A15, HMS2097A15, ZINC159590, KS-000002EY, ZX-AT024658, 5048AE, BDBM50125053, MFCD00052019, 3-(1-Pyrrolin-2-yl)pyridine, 8CI, AKOS005254654, CCG-214475, CS-W001909, FCH1114078, GL-0072, MCULE-7478723183, NCGC00016493-01, NCGC00016493-02, NCGC00163359-01, CAS-532-12-7, KB-177531, TR-018818, 3-(3,4-Dihydro-2H-pyrrol-5-yl)-Pyridine, FT-0629049, ST50824026, 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine #, C10160, X-4253, 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine, 9CI, I07-345, 3-(4,5-Dihydro-3H-pyrrol-2-yl)pyridine (Myosmine), BRD-K67556876-001-03-1, BRD-K67556876-001-04-9, Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)- (9CI)

ID: 500

InChIKey: DPSPPJIUMHPXMA-UHFFFAOYSA-N
SMILES: CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O

biological descriptors:

CFTR relevance: unspecified

Category:
Influence on CFTR function unknown
Order of interaction unknown
subcellular compartment unknown

reference list:

"R Robert" "GW Carlile" "D Rotin" "J Goepp" "J Liao" "E Matthes" "JW Hanrahan" "B Kus" "SD Macknight" "DY Thomas"

CID is 3374
synonyms found at PubChem are:
flumequine, 42835-25-6, Flumigal, Apurone, 9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid, Flumequinum, Flumequino, Flumiquil, Flumisol, Imequyl, Flumix, R 802 (bactericide), Flumequinum [INN-Latin], Flumequino [INN-Spanish], HSDB 7034, R 802, EINECS 255-962-6, MLS000069546, CHEBI:85269, DPSPPJIUMHPXMA-UHFFFAOYSA-N, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-1h,5h-benzo[ij]quinolizine-2-carboxylic acid, NCGC00018211-03, SMR000058826, 1H,5H-Benzo(ij)quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-, 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid, DSSTox_CID_25623, DSSTox_RID_81008, DSSTox_GSID_45623, Q-201123, 6,7-Dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-quinolizine-2-carboxylic acid, 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-, 9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid, SR-01000000130, Fantacin, Flumequin, Flumequine [USAN:BAN:INN], Flumequine [USAN:INN:BAN], (RS)-9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, Prestwick_603, Apurone (TN), CAS-42835-25-6, (+/-)-Flumequine, Spectrum_000367, AC1L1FSH, Flumequine (USAN/INN), Opera_ID_1399, Prestwick0_000204, Prestwick1_000204, Prestwick2_000204, Prestwick3_000204, Spectrum2_001200, Spectrum3_001417, Spectrum4_000826, Spectrum5_001532, R-802, SCHEMBL49829, BSPBio_000187, BSPBio_003094, KBioGR_001371, KBioSS_000847, MLS001074120, DivK1c_000089, SPECTRUM1500992, SPBio_001279, SPBio_002108, BPBio1_000207, CHEMBL370252, DTXSID5045623, CHEBI:94431, CTK1D6186, HMS500E11, KBio1_000089, KBio2_000847, KBio2_003415, KBio2_005983, KBio3_002314, MolPort-003-666-337, NINDS_000089, HMS1568J09, HMS1921O10, HMS2092O08, HMS2095J09, HMS2230F14, HMS3373O15, HMS3652K09, HMS3712J09, Pharmakon1600-01500992, EBD52299, HY-B0526, KS-00000G9K, Tox21_110840, ANW-59991, CCG-40315, GA3854, MFCD00079298, NSC757806, s3181, SBB012470, fluoro-methyl-oxo-[?]carboxylic acid, 6,7-dihydro-9-fluoro-5-methyl-1-oxo- 1H,5H-quinolizine-2-carboxylic acid, AKOS015904879, Tox21_110840_1, AC-1284, API0002722, CS-2747, DB08972, HS-0096, MCULE-1576355150, NSC-757806, IDI1_000089, NCGC00018211-02, NCGC00018211-04, NCGC00018211-05, NCGC00018211-06, NCGC00018211-10, NCGC00089803-02, NCGC00089803-03, NCGC00178300-01, NCGC00178300-02, AK-27078, AN-15109, BC204036, CC-28464, LS-40210, ST072199, SBI-0051623.P002, AB1009285, AX8130483, KB-250572, TR-016689, F0832, FT-0626439, ST24045868, D02302, Flumequine, VETRANAL(TM), analytical standard, AB00052187_17, AB00052187_18, 835F256, C-16315, SR-01000000130-2, SR-01000000130-4, BRD-A69777949-001-05-1, BRD-A69777949-001-15-0, 1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)sulfonyl]-, Flumequine, European Pharmacopoeia (EP) Reference Standard, 42835-25-6,143984-63-8,42835-68-7(sodiumsalt), 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo, 1H,5H-Benzo[ij]quinolizine-2-carboxylicacid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-, 6,7Dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]-quinolizine-2-carboxylic acid, 9-Fluoro-1,5,6,7-tetrahydro-5-methyl-1-oxopyrido[3,2,1-ij]quinoline-2-carboxylic Acid, 143984-63-8, 7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.0;{5,13}]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid